locus-tag	class	description
E6C72_00035	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
E6C72_00050	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
E6C72_00060	COG2910	NAD(P)H-binding
E6C72_00085	COG0742	ribosomal rna small subunit methyltransferase
E6C72_00090	COG1187	pseudouridine synthase activity
E6C72_00095	COG0590	tRNA wobble adenosine to inosine editing
E6C72_00115	COG1570	exodeoxyribonuclease VII activity
E6C72_00130	COG0418	dihydroorotase activity
E6C72_00150	COG1404	Belongs to the peptidase S8 family
E6C72_00160	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
E6C72_00165	COG0193	aminoacyl-tRNA hydrolase activity
E6C72_00170	COG0012	GTP binding
E6C72_00175	COG1283	sodium-dependent phosphate transmembrane transporter activity
E6C72_00180	COG5001	Diguanylate cyclase
E6C72_00180	COG3300	MHYT domain
E6C72_00190	COG1454	alcohol dehydrogenase
E6C72_00210	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E6C72_00225	COG2945	thiolester hydrolase activity
E6C72_00230	COG1045	serine acetyltransferase
E6C72_00240	COG1104	cysteine desulfurase activity
E6C72_00245	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
E6C72_00255	COG0482	sulfurtransferase activity
E6C72_00265	COG0745	RESPONSE REGULATOR receiver
E6C72_00265	COG3706	GGDEF domain
E6C72_00270	COG3284	Transcriptional regulator
E6C72_00285	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
E6C72_00315	COG2001	Belongs to the MraZ family
E6C72_00335	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
E6C72_00345	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E6C72_00350	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
E6C72_00360	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
E6C72_00370	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
E6C72_00375	COG0812	UDP-N-acetylmuramate dehydrogenase activity
E6C72_00380	COG1181	Belongs to the D-alanine--D-alanine ligase family
E6C72_00385	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
E6C72_00390	COG0849	cell division
E6C72_00395	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
E6C72_00410	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
E6C72_00430	COG0248	Ppx GppA phosphatase
E6C72_00440	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
E6C72_00445	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
E6C72_00460	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
E6C72_00530	COG0354	folic acid binding
E6C72_00545	COG0546	phosphoglycolate phosphatase activity
E6C72_00550	COG0564	pseudouridine synthase activity
E6C72_00555	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
E6C72_00560	COG1335	isochorismatase
E6C72_00570	COG1136	(ABC) transporter
E6C72_00580	COG0442	prolyl-tRNA aminoacylation
E6C72_00595	COG0519	Catalyzes the synthesis of GMP from XMP
E6C72_00625	COG1007	ATP synthesis coupled electron transport
E6C72_00640	COG0713	ATP synthesis coupled electron transport
E6C72_00655	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
E6C72_00660	COG1034	ATP synthesis coupled electron transport
E6C72_00670	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
E6C72_00675	COG0649	NAD binding
E6C72_00680	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E6C72_00685	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E6C72_00690	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E6C72_00770	COG0500	methyltransferase
E6C72_00775	COG0140	phosphoribosyl-ATP diphosphatase activity
E6C72_00780	COG0704	Plays a role in the regulation of phosphate uptake
E6C72_00785	COG2862	Uncharacterized protein family, UPF0114
E6C72_00805	COG0768	penicillin binding
E6C72_00810	COG1215	transferase activity, transferring glycosyl groups
E6C72_00820	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
E6C72_00830	COG0028	Belongs to the TPP enzyme family
E6C72_00835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E6C72_00840	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
E6C72_00845	COG3830	Belongs to the UPF0237 family
E6C72_00845	COG0560	Phosphoserine phosphatase
E6C72_00855	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
E6C72_00870	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
E6C72_00875	COG0830	nickel cation binding
E6C72_00880	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
E6C72_00885	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
E6C72_00890	COG0804	urea catabolic process
E6C72_00895	COG0832	Belongs to the urease beta subunit family
E6C72_00900	COG0831	urea catabolic process
E6C72_00905	COG0829	nickel cation binding
E6C72_00910	COG2197	response regulator
E6C72_00915	COG2197	response regulator
E6C72_00920	COG0693	protein deglycase activity
E6C72_00935	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
E6C72_00940	COG0717	Belongs to the dCTP deaminase family
E6C72_00960	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E6C72_00995	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
E6C72_01005	COG0557	exoribonuclease II activity
E6C72_01010	COG0793	Belongs to the peptidase S41A family
E6C72_01015	COG0267	Belongs to the bacterial ribosomal protein bL33 family
E6C72_01020	COG1262	PFAM Formylglycine-generating sulfatase enzyme
E6C72_01035	COG1380	Effector of murein hydrolase LrgA
E6C72_01040	COG1346	cytolysis
E6C72_01070	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
E6C72_01100	COG4191	Histidine kinase
E6C72_01100	COG0784	Response regulator, receiver
E6C72_01120	COG1131	(ABC) transporter
E6C72_01130	COG1309	transcriptional regulator
E6C72_01150	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E6C72_01165	COG5554	nitrogen fixation
E6C72_01190	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E6C72_01215	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E6C72_01225	COG0745	RESPONSE REGULATOR receiver
E6C72_01230	COG2176	DNA-directed DNA polymerase activity
E6C72_01230	COG5002	protein histidine kinase activity
E6C72_01240	COG5002	protein histidine kinase activity
E6C72_01245	COG2204	response regulator
E6C72_01250	COG3852	Histidine kinase
E6C72_01260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E6C72_01305	COG0752	glycyl-tRNA synthetase alpha subunit
E6C72_01310	COG0751	glycine-tRNA ligase activity
E6C72_01340	COG3437	response regulator, receiver
E6C72_01340	COG2770	Histidine kinase
E6C72_01345	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
E6C72_01350	COG1234	tRNA 3'-trailer cleavage
E6C72_01355	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
E6C72_01360	COG0047	phosphoribosylformylglycinamidine synthase activity
E6C72_01365	COG0004	ammonium transporteR
E6C72_01370	COG0312	modulator of DNA gyrase
E6C72_01390	COG1846	Transcriptional regulator
E6C72_01400	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
E6C72_01440	COG0463	Glycosyl transferase, family 2
E6C72_01445	COG0840	transmembrane signaling receptor activity
E6C72_01455	COG0840	transmembrane signaling receptor activity
E6C72_01465	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
E6C72_01475	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
E6C72_01480	COG3118	belongs to the thioredoxin family
E6C72_01490	COG2835	tetraacyldisaccharide 4'-kinase activity
E6C72_01500	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
E6C72_01515	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_01520	COG0183	Belongs to the thiolase family
E6C72_01525	COG3243	poly(R)-hydroxyalkanoic acid synthase
E6C72_01530	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
E6C72_01565	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
E6C72_01570	COG0842	Transport permease protein
E6C72_01575	COG1132	(ABC) transporter
E6C72_01580	COG0254	rRNA binding
E6C72_01590	COG0071	Belongs to the small heat shock protein (HSP20) family
E6C72_01605	COG0261	This protein binds to 23S rRNA in the presence of protein L20
E6C72_01610	COG0211	Belongs to the bacterial ribosomal protein bL27 family
E6C72_01615	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
E6C72_01625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E6C72_01640	COG0793	Belongs to the peptidase S41A family
E6C72_01645	COG4942	peptidase
E6C72_01650	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
E6C72_01655	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
E6C72_01660	COG0799	negative regulation of ribosome biogenesis
E6C72_01680	COG1051	belongs to the nudix hydrolase family
E6C72_01690	COG0745	RESPONSE REGULATOR receiver
E6C72_01695	COG0643	Histidine kinase
E6C72_01695	COG2198	Histidine kinase
E6C72_01700	COG0835	chemotaxis
E6C72_01705	COG0840	transmembrane signaling receptor activity
E6C72_01715	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
E6C72_01720	COG2201	protein-glutamate methylesterase activity
E6C72_01725	COG0840	transmembrane signaling receptor activity
E6C72_01730	COG1366	Belongs to the anti-sigma-factor antagonist family
E6C72_01750	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
E6C72_01755	COG0579	oxidoreductase
E6C72_01760	COG0071	Belongs to the small heat shock protein (HSP20) family
E6C72_01780	COG0840	transmembrane signaling receptor activity
E6C72_01780	COG0840	transmembrane signaling receptor activity
E6C72_01790	COG1322	Protein conserved in bacteria
E6C72_01805	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_01855	COG1278	Cold shock
E6C72_01860	COG1902	pentaerythritol trinitrate reductase activity
E6C72_01865	COG0406	alpha-ribazole phosphatase activity
E6C72_01865	COG0328	RNA-DNA hybrid ribonuclease activity
E6C72_01870	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
E6C72_01890	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
E6C72_01900	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E6C72_01905	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
E6C72_01920	COG2193	ferroxidase activity
E6C72_01930	COG1192	Involved in chromosome partitioning
E6C72_01935	COG0009	L-threonylcarbamoyladenylate synthase
E6C72_01940	COG0277	FAD linked oxidase domain protein
E6C72_01945	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
E6C72_01950	COG0431	NADPH-dependent FMN reductase
E6C72_01955	COG0559	Belongs to the binding-protein-dependent transport system permease family
E6C72_01960	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E6C72_01965	COG0747	negative chemotaxis
E6C72_01980	COG0101	tRNA pseudouridine synthase activity
E6C72_01985	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
E6C72_01990	COG0242	peptide deformylase activity
E6C72_01995	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
E6C72_02010	COG0513	Belongs to the DEAD box helicase family
E6C72_02020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E6C72_02025	COG1199	ATP-dependent helicase activity
E6C72_02025	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E6C72_02030	COG0840	transmembrane signaling receptor activity
E6C72_02030	COG2972	Histidine kinase
E6C72_02040	COG0679	Auxin Efflux Carrier
E6C72_02050	COG2084	Dehydrogenase
E6C72_02060	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
E6C72_02075	COG1595	DNA-templated transcription, initiation
E6C72_02090	COG4251	negative regulation of phosphorylation
E6C72_02090	COG3706	GGDEF domain
E6C72_02090	COG2203	Gaf domain
E6C72_02090	COG5001	Diguanylate cyclase
E6C72_02110	COG3279	Response regulator of the LytR AlgR family
E6C72_02120	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
E6C72_02135	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
E6C72_02150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E6C72_02165	COG2350	Protein conserved in bacteria
E6C72_02185	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
E6C72_02190	COG2205	protein histidine kinase activity
E6C72_02200	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
E6C72_02210	COG2885	chlorophyll binding
E6C72_02220	COG0586	Pfam SNARE associated Golgi protein
E6C72_02240	COG1278	Cold shock
E6C72_02270	COG0410	ABC transporter
E6C72_02285	COG0559	Belongs to the binding-protein-dependent transport system permease family
E6C72_02300	COG3327	negative regulation of DNA-templated transcription, initiation
E6C72_02315	COG0840	transmembrane signaling receptor activity
E6C72_02325	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
E6C72_02340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E6C72_02355	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
E6C72_02360	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
E6C72_02370	COG0167	dihydroorotate dehydrogenase activity
E6C72_02435	COG2032	superoxide dismutase activity
E6C72_02440	COG0513	Belongs to the DEAD box helicase family
E6C72_02465	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
E6C72_02475	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
E6C72_02495	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
E6C72_02505	COG4974	Belongs to the 'phage' integrase family
E6C72_02510	COG0840	transmembrane signaling receptor activity
E6C72_02520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E6C72_02540	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_02545	COG0534	Mate efflux family protein
E6C72_02550	COG1309	transcriptional regulator
E6C72_02570	COG4191	Histidine kinase
E6C72_02580	COG4106	trans-aconitate 2-methyltransferase activity
E6C72_02595	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
E6C72_02605	COG0181	hydroxymethylbilane synthase activity
E6C72_02635	COG1442	glycosyl transferase family 8
E6C72_02635	COG1216	Glycosyl transferase, family 2
E6C72_02660	COG1842	Phage shock protein A
E6C72_02665	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
E6C72_02670	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
E6C72_02680	COG0825	malonyl-CoA metabolic process
E6C72_02685	COG2239	Acts as a magnesium transporter
E6C72_02700	COG0671	phosphoesterase, PA-phosphatase related
E6C72_02725	COG1254	Belongs to the acylphosphatase family
E6C72_02730	COG0318	PFAM AMP-dependent synthetase and ligase
E6C72_02745	COG2719	SpoVR family
E6C72_02750	COG2718	Belongs to the UPF0229 family
E6C72_02755	COG2766	serine protein kinase
E6C72_02770	COG3474	cytochrome
E6C72_02775	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
E6C72_02780	COG0077	Prephenate dehydratase
E6C72_02805	COG4166	transmembrane transport
E6C72_02810	COG4166	transmembrane transport
E6C72_02815	COG4174	ABC transporter (Permease)
E6C72_02820	COG4239	(ABC) transporter, permease
E6C72_02825	COG4172	Belongs to the ABC transporter superfamily
E6C72_02830	COG1703	isobutyryl-CoA mutase activity
E6C72_02840	COG0227	Belongs to the bacterial ribosomal protein bL28 family
E6C72_02845	COG2137	regulation of response to DNA damage stimulus
E6C72_02850	COG0842	Transport permease protein
E6C72_02855	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
E6C72_02860	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
E6C72_02865	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
E6C72_02890	COG3158	transport of potassium into the cell
E6C72_02915	COG0587	DNA-directed DNA polymerase activity
E6C72_02940	COG0126	phosphoglycerate kinase activity
E6C72_02955	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
E6C72_02980	COG1177	transmembrane transport
E6C72_02985	COG1176	ABC-type spermidine putrescine transport system, permease component I
E6C72_03000	COG0156	8-amino-7-oxononanoate synthase activity
E6C72_03010	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
E6C72_03015	COG3706	GGDEF domain
E6C72_03015	COG0745	RESPONSE REGULATOR receiver
E6C72_03020	COG0135	phosphoribosylanthranilate isomerase activity
E6C72_03040	COG0840	transmembrane signaling receptor activity
E6C72_03045	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_03060	COG1793	dna ligase
E6C72_03070	COG2313	pseudouridylate synthase activity
E6C72_03085	COG0753	catalase activity
E6C72_03095	COG1741	Belongs to the pirin family
E6C72_03100	COG0004	ammonium transporteR
E6C72_03105	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
E6C72_03110	COG0297	glycogen (starch) synthase activity
E6C72_03130	COG0574	Belongs to the PEP-utilizing enzyme family
E6C72_03130	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E6C72_03140	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E6C72_03150	COG0539	negative regulation of cytoplasmic translation
E6C72_03210	COG1238	metal cluster binding
E6C72_03215	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E6C72_03235	COG1674	ftsk spoiiie
E6C72_03240	COG2318	DinB family
E6C72_03250	COG5002	protein histidine kinase activity
E6C72_03255	COG2205	protein histidine kinase activity
E6C72_03275	COG0243	molybdopterin cofactor binding
E6C72_03285	COG3005	denitrification pathway
E6C72_03310	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
E6C72_03315	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E6C72_03330	COG1522	sequence-specific DNA binding
E6C72_03335	COG3660	Nucleoside-diphosphate-sugar epimerase
E6C72_03380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E6C72_03390	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
E6C72_03395	COG0861	Integral membrane protein TerC family
E6C72_03410	COG0583	DNA-binding transcription factor activity
E6C72_03430	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E6C72_03435	COG0138	bifunctional purine biosynthesis protein purh
E6C72_03445	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
E6C72_03445	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
E6C72_03455	COG1024	Enoyl-CoA hydratase
E6C72_03465	COG0477	Major facilitator Superfamily
E6C72_03470	COG0583	DNA-binding transcription factor activity
E6C72_03490	COG1272	protein, Hemolysin III
E6C72_03515	COG0137	argininosuccinate synthase activity
E6C72_03520	COG0840	transmembrane signaling receptor activity
E6C72_03525	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
E6C72_03530	COG0840	transmembrane signaling receptor activity
E6C72_03540	COG0783	Belongs to the Dps family
E6C72_03565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E6C72_03580	COG0776	regulation of translation
E6C72_03590	COG2423	ornithine cyclodeaminase activity
E6C72_03595	COG3920	Histidine kinase
E6C72_03690	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E6C72_03700	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E6C72_03725	COG0820	rRNA (adenine-C2-)-methyltransferase activity
E6C72_03740	COG3437	response regulator, receiver
E6C72_03740	COG2770	Histidine kinase
E6C72_03745	COG3813	Protein conserved in bacteria
E6C72_03750	COG0625	glutathione transferase activity
E6C72_03755	COG1473	amidohydrolase
E6C72_03765	COG5001	Diguanylate cyclase
E6C72_03805	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E6C72_03815	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
E6C72_03825	COG3162	membrane
E6C72_03850	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
E6C72_03860	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
E6C72_03865	COG0542	response to heat
E6C72_03885	COG2890	protein-(glutamine-N5) methyltransferase activity
E6C72_03895	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
E6C72_03900	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
E6C72_03940	COG0739	heme binding
E6C72_03960	COG0386	Belongs to the glutathione peroxidase family
E6C72_03965	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E6C72_03970	COG4133	protoheme IX ABC transporter activity
E6C72_04005	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
E6C72_04010	COG0792	nuclease activity
E6C72_04025	COG0180	Tryptophanyl-tRNA synthetase
E6C72_04030	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
E6C72_04045	COG0606	chelatase, subunit chli
E6C72_04070	COG1420	regulation of RNA biosynthetic process
E6C72_04080	COG0745	RESPONSE REGULATOR receiver
E6C72_04090	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
E6C72_04105	COG0730	response to heat
E6C72_04120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E6C72_04135	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E6C72_04155	COG0668	transmembrane transport
E6C72_04160	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
E6C72_04170	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E6C72_04175	COG0302	gtp cyclohydrolase
E6C72_04180	COG2967	ApaG domain
E6C72_04190	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
E6C72_04195	COG1702	phosphate starvation-inducible protein PhoH
E6C72_04205	COG1253	flavin adenine dinucleotide binding
E6C72_04210	COG0815	Transfers the fatty acyl group on membrane lipoproteins
E6C72_04215	COG1396	sequence-specific DNA binding
E6C72_04220	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
E6C72_04225	COG0220	tRNA (guanine-N7-)-methyltransferase activity
E6C72_04230	COG2329	Antibiotic biosynthesis monooxygenase
E6C72_04235	COG0779	Required for maturation of 30S ribosomal subunits
E6C72_04260	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
E6C72_04265	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
E6C72_04270	COG1185	polyribonucleotide nucleotidyltransferase activity
E6C72_04275	COG2378	regulation of single-species biofilm formation
E6C72_04290	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E6C72_04300	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
E6C72_04305	COG1138	Cytochrome C-type biogenesis protein
E6C72_04310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E6C72_04315	COG3088	subunit of a heme lyase
E6C72_04320	COG4235	cytochrome complex assembly
E6C72_04325	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
E6C72_04385	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
E6C72_04390	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
E6C72_04395	COG4395	Tim44
E6C72_04405	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
E6C72_04410	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
E6C72_04420	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
E6C72_04445	COG0237	dephospho-CoA kinase activity
E6C72_04450	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E6C72_04460	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E6C72_04465	COG1331	Highly conserved protein containing a thioredoxin domain
E6C72_04485	COG0445	tRNA wobble uridine modification
E6C72_04490	COG0357	Ribosomal RNA small subunit methyltransferase G
E6C72_04495	COG1192	Involved in chromosome partitioning
E6C72_04500	COG1475	DNA binding
E6C72_04505	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
E6C72_04510	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E6C72_04515	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
E6C72_04520	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
E6C72_04525	COG2814	Major facilitator Superfamily
E6C72_04530	COG0280	phosphate acetyltransferase
E6C72_04530	COG0281	malic enzyme
E6C72_04555	COG5002	protein histidine kinase activity
E6C72_04560	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
E6C72_04565	COG0573	inorganic phosphate transmembrane transporter activity
E6C72_04575	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
E6C72_04580	COG0745	RESPONSE REGULATOR receiver
E6C72_04590	COG0670	Belongs to the BI1 family
E6C72_04605	COG4181	ATPase activity
E6C72_04620	COG0667	Aldo Keto reductase
E6C72_04625	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
E6C72_04630	COG3706	GGDEF domain
E6C72_04635	COG0484	heat shock protein binding
E6C72_04640	COG0443	Heat shock 70 kDa protein
E6C72_04660	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
E6C72_04670	COG0456	acetyltransferase
E6C72_04725	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
E6C72_04735	COG0745	RESPONSE REGULATOR receiver
E6C72_04740	COG0642	Histidine kinase
E6C72_04760	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E6C72_04760	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E6C72_04770	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E6C72_04785	COG0501	Belongs to the peptidase M48B family
E6C72_04790	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
E6C72_04810	COG0271	Belongs to the BolA IbaG family
E6C72_04835	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
E6C72_04855	COG4974	Belongs to the 'phage' integrase family
E6C72_04865	COG2154	pterin-4-alpha-carbinolamine dehydratase
E6C72_04875	COG1573	uracil-dna glycosylase
E6C72_04885	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
E6C72_04890	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E6C72_04905	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E6C72_04910	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
E6C72_04915	COG3706	GGDEF domain
E6C72_04970	COG0517	IMP dehydrogenase activity
E6C72_04970	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
E6C72_04985	COG1137	ATPase activity
E6C72_04990	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
E6C72_04995	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
E6C72_05000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E6C72_05005	COG4636	protein conserved in cyanobacteria
E6C72_05010	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
E6C72_05020	COG2070	2-Nitropropane dioxygenase
E6C72_05030	COG1733	regulation of RNA biosynthetic process
E6C72_05035	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
E6C72_05040	COG0187	DNA topoisomerase II activity
E6C72_05045	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
E6C72_05050	COG0592	DNA-directed DNA polymerase activity
E6C72_05070	COG3118	belongs to the thioredoxin family
E6C72_05075	COG1074	ATP-dependent DNA helicase activity
E6C72_05080	COG2887	Belongs to the helicase family. UvrD subfamily
E6C72_05085	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
E6C72_05090	COG3178	'Phosphotransferase
E6C72_05095	COG0802	atpase or kinase
E6C72_05110	COG2205	protein histidine kinase activity
E6C72_05115	COG5002	protein histidine kinase activity
E6C72_05115	COG2205	protein histidine kinase activity
E6C72_05115	COG0784	Response regulator, receiver
E6C72_05120	COG0756	dUTP diphosphatase activity
E6C72_05125	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
E6C72_05130	COG2204	response regulator
E6C72_05135	COG1278	Cold shock
E6C72_05140	COG2205	protein histidine kinase activity
E6C72_05140	COG0784	Response regulator, receiver
E6C72_05145	COG0133	tryptophan synthase activity
E6C72_05155	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
E6C72_05160	COG0285	dihydrofolate synthase activity
E6C72_05175	COG1872	DUF167
E6C72_05180	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
E6C72_05185	COG0598	Magnesium transport protein CorA
E6C72_05205	COG0039	L-malate dehydrogenase activity
E6C72_05230	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
E6C72_05235	COG4166	transmembrane transport
E6C72_05240	COG0747	negative chemotaxis
E6C72_05250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E6C72_05260	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
E6C72_05270	COG0840	transmembrane signaling receptor activity
E6C72_05285	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
E6C72_05295	COG1024	Enoyl-CoA hydratase
E6C72_05300	COG0268	Binds directly to 16S ribosomal RNA
E6C72_05305	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
E6C72_05310	COG3706	GGDEF domain
E6C72_05315	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E6C72_05320	COG3842	ATPase activity
E6C72_05330	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
E6C72_05350	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
E6C72_05360	COG0745	RESPONSE REGULATOR receiver
E6C72_05380	COG2264	protein methyltransferase activity
E6C72_05410	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
E6C72_05480	COG0406	alpha-ribazole phosphatase activity
E6C72_05500	COG0745	RESPONSE REGULATOR receiver
E6C72_05580	COG1509	lysine 2,3-aminomutase activity
E6C72_05585	COG0584	glycerophosphoryl diester phosphodiesterase
E6C72_05610	COG2205	protein histidine kinase activity
E6C72_05610	COG2202	Pas domain
E6C72_05620	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E6C72_05625	COG3162	membrane
E6C72_05640	COG0318	PFAM AMP-dependent synthetase and ligase
E6C72_05655	COG1960	acyl-CoA dehydrogenase activity
E6C72_05660	COG1187	pseudouridine synthase activity
E6C72_05670	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
E6C72_05680	COG0291	Belongs to the bacterial ribosomal protein bL35 family
E6C72_05685	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
E6C72_05690	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
E6C72_05705	COG0784	Response regulator, receiver
E6C72_05705	COG3437	response regulator, receiver
E6C72_05715	COG0583	DNA-binding transcription factor activity
E6C72_05725	COG0252	asparaginase activity
E6C72_05750	COG1643	Atp-dependent helicase
E6C72_05785	COG4191	Histidine kinase
E6C72_05800	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E6C72_05805	COG0045	succinate-CoA ligase (ADP-forming) activity
E6C72_05810	COG0039	L-malate dehydrogenase activity
E6C72_05830	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
E6C72_05840	COG0640	Transcriptional regulator
E6C72_05855	COG1970	mechanosensitive ion channel activity
E6C72_05860	COG0653	protein targeting
E6C72_05865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E6C72_05870	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
E6C72_05875	COG0494	nUDIX hydrolase
E6C72_05885	COG0514	ATP-dependent DNA helicase (RecQ)
E6C72_05895	COG0024	Methionine aminopeptidase
E6C72_05900	COG1489	DNA binding
E6C72_05905	COG1058	Belongs to the CinA family
E6C72_05905	COG1546	Belongs to the CinA family
E6C72_05925	COG0745	RESPONSE REGULATOR receiver
E6C72_05950	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E6C72_05955	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E6C72_05965	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
E6C72_05970	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
E6C72_05980	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
E6C72_05990	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
E6C72_06005	COG3278	Belongs to the heme-copper respiratory oxidase family
E6C72_06040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E6C72_06045	COG1612	heme a metabolic process
E6C72_06050	COG3772	lysozyme
E6C72_06060	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
E6C72_06065	COG0459	protein refolding
E6C72_06080	COG4566	intracellular signal transduction
E6C72_06100	COG0583	DNA-binding transcription factor activity
E6C72_06120	COG4608	Belongs to the ABC transporter superfamily
E6C72_06125	COG0444	Belongs to the ABC transporter superfamily
E6C72_06135	COG0601	transmembrane transport
E6C72_06140	COG0492	ferredoxin-NADP+ reductase activity
E6C72_06150	COG1695	Transcriptional regulator
E6C72_06165	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
E6C72_06175	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E6C72_06190	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E6C72_06195	COG1595	DNA-templated transcription, initiation
E6C72_06205	COG0560	Phosphoserine phosphatase
E6C72_06205	COG3830	Belongs to the UPF0237 family
E6C72_06220	COG2202	Pas domain
E6C72_06220	COG2205	protein histidine kinase activity
E6C72_06240	COG0454	-acetyltransferase
E6C72_06240	COG0456	acetyltransferase
E6C72_06260	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
E6C72_06265	COG3290	protein histidine kinase activity
E6C72_06265	COG0840	transmembrane signaling receptor activity
E6C72_06270	COG2022	thiamine diphosphate biosynthetic process
E6C72_06270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E6C72_06280	COG2022	thiamine diphosphate biosynthetic process
E6C72_06365	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
E6C72_06370	COG3108	Peptidase M15
E6C72_06380	COG3038	cytochrome b561
E6C72_06390	COG2205	protein histidine kinase activity
E6C72_06395	COG0745	RESPONSE REGULATOR receiver
E6C72_06400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E6C72_06420	COG0257	Belongs to the bacterial ribosomal protein bL36 family
E6C72_06425	COG0277	FAD linked oxidase domain protein
E6C72_06430	COG0277	FAD linked oxidase domain protein
E6C72_06435	COG0247	lactate metabolic process
E6C72_06460	COG1454	alcohol dehydrogenase
E6C72_06465	COG1960	acyl-CoA dehydrogenase activity
E6C72_06485	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E6C72_06490	COG2171	N-acyltransferase activity
E6C72_06525	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E6C72_06530	COG0228	four-way junction DNA binding
E6C72_06535	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
E6C72_06540	COG0336	Belongs to the RNA methyltransferase TrmD family
E6C72_06545	COG0335	large ribosomal subunit rRNA binding
E6C72_06550	COG0230	Belongs to the bacterial ribosomal protein bL34 family
E6C72_06560	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
E6C72_06565	COG0706	membrane insertase activity
E6C72_06570	COG0218	Necessary for normal cell division and for the maintenance of normal septation
E6C72_06580	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
E6C72_06595	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
E6C72_06605	COG1530	ribonuclease E activity
E6C72_06610	COG0860	N-Acetylmuramoyl-L-alanine amidase
E6C72_06660	COG1940	carbohydrate kinase activity
E6C72_06690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E6C72_06695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E6C72_06725	COG0411	ABC transporter
E6C72_06795	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
E6C72_06815	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
E6C72_06820	COG0081	regulation of translation
E6C72_06825	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
E6C72_06835	COG0085	RNA polymerase activity
E6C72_06840	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
E6C72_06850	COG0049	tRNA binding
E6C72_06860	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
E6C72_06865	COG0051	transcription antitermination factor activity, RNA binding
E6C72_06875	COG0088	Forms part of the polypeptide exit tunnel
E6C72_06880	COG0089	rRNA binding
E6C72_06885	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
E6C72_06890	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
E6C72_06895	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
E6C72_06900	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
E6C72_06905	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
E6C72_06910	COG0255	Belongs to the universal ribosomal protein uL29 family
E6C72_06915	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
E6C72_06925	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
E6C72_06935	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
E6C72_06940	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
E6C72_06945	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
E6C72_06955	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
E6C72_06960	COG1841	ribosomal large subunit assembly
E6C72_06965	COG0200	Binds to the 23S rRNA
E6C72_06975	COG0563	adenylate kinase activity
E6C72_06985	COG0697	spore germination
E6C72_07000	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
E6C72_07005	COG3842	ATPase activity
E6C72_07025	COG2267	carboxylic ester hydrolase activity
E6C72_07035	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
E6C72_07080	COG1285	pathogenesis
E6C72_07090	COG0196	riboflavin kinase activity
E6C72_07095	COG2030	dehydratase
E6C72_07100	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
E6C72_07105	COG2267	carboxylic ester hydrolase activity
E6C72_07115	COG0628	permease
E6C72_07145	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
E6C72_07150	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
E6C72_07160	COG1597	lipid kinase activity
E6C72_07175	COG1280	lysine exporter protein (LysE YggA)
E6C72_07180	COG3706	GGDEF domain
E6C72_07180	COG2203	Gaf domain
E6C72_07180	COG4251	negative regulation of phosphorylation
E6C72_07180	COG5001	Diguanylate cyclase
E6C72_07185	COG0220	tRNA (guanine-N7-)-methyltransferase activity
E6C72_07185	COG1519	Transferase
E6C72_07190	COG1663	tetraacyldisaccharide 4'-kinase activity
E6C72_07200	COG1280	lysine exporter protein (LysE YggA)
E6C72_07210	COG2205	protein histidine kinase activity
E6C72_07210	COG0784	Response regulator, receiver
E6C72_07210	COG5002	protein histidine kinase activity
E6C72_07220	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
E6C72_07225	COG0644	oxidoreductase
E6C72_07280	COG1902	pentaerythritol trinitrate reductase activity
E6C72_07290	COG2962	Rard protein
E6C72_07295	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
E6C72_07305	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
E6C72_07320	COG2205	protein histidine kinase activity
E6C72_07335	COG0395	ABC-type sugar transport system, permease component
E6C72_07340	COG3842	ATPase activity
E6C72_07345	COG5508	conserved small protein
E6C72_07350	COG0501	Belongs to the peptidase M48B family
E6C72_07400	COG1366	Belongs to the anti-sigma-factor antagonist family
E6C72_07425	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
E6C72_07450	COG1686	Belongs to the peptidase S11 family
E6C72_07465	COG2205	protein histidine kinase activity
E6C72_07465	COG2202	Pas domain
E6C72_07470	COG5002	protein histidine kinase activity
E6C72_07475	COG2205	protein histidine kinase activity
E6C72_07485	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
E6C72_07500	COG0166	Belongs to the GPI family
E6C72_07505	COG0612	Peptidase, M16
E6C72_07510	COG0612	Peptidase, M16
E6C72_07520	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
E6C72_07555	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
E6C72_07560	COG2703	oxygen carrier activity
E6C72_07565	COG0840	transmembrane signaling receptor activity
E6C72_07575	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
E6C72_07590	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E6C72_07605	COG0840	transmembrane signaling receptor activity
E6C72_07620	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
E6C72_07625	COG0746	molybdenum cofactor guanylyltransferase activity
E6C72_07650	COG3383	formate dehydrogenase (NAD+) activity
E6C72_07655	COG0437	4 iron, 4 sulfur cluster binding
E6C72_07670	COG0235	Class ii aldolase
E6C72_07675	COG0784	Response regulator, receiver
E6C72_07675	COG5002	protein histidine kinase activity
E6C72_07680	COG3384	dioxygenase
E6C72_07685	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
E6C72_07690	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
E6C72_07695	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
E6C72_07700	COG0356	it plays a direct role in the translocation of protons across the membrane
E6C72_07710	COG1999	signal sequence binding
E6C72_07715	COG0840	transmembrane signaling receptor activity
E6C72_07720	COG1702	phosphate starvation-inducible protein PhoH
E6C72_07725	COG0850	regulation of cytokinetic process
E6C72_07730	COG2894	cell division
E6C72_07735	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
E6C72_07750	COG0840	transmembrane signaling receptor activity
E6C72_07750	COG5278	phosphoserine phosphatase activity
E6C72_07760	COG4948	Mandelate Racemase Muconate Lactonizing
E6C72_07770	COG1573	uracil-dna glycosylase
E6C72_07795	COG1385	rRNA (uridine-N3-)-methyltransferase activity
E6C72_07805	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
E6C72_07810	COG5420	small protein containing a coiled-coil domain
E6C72_07825	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
E6C72_07830	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
E6C72_07880	COG0121	glutamine amidotransferase
E6C72_07890	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
E6C72_07895	COG0552	protein localization to endoplasmic reticulum
E6C72_07900	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
E6C72_07905	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
E6C72_07925	COG0583	DNA-binding transcription factor activity
E6C72_07960	COG2301	Belongs to the HpcH HpaI aldolase family
E6C72_07965	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
E6C72_07970	COG2205	protein histidine kinase activity
E6C72_07970	COG2202	Pas domain
E6C72_07975	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
E6C72_07985	COG2972	Histidine kinase
E6C72_07985	COG0840	transmembrane signaling receptor activity
E6C72_07995	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
E6C72_08000	COG1063	alcohol dehydrogenase
E6C72_08010	COG0596	Alpha beta hydrolase
E6C72_08010	COG0508	dehydrogenase complex catalyzes the overall conversion of
E6C72_08015	COG0022	dehydrogenase e1 component
E6C72_08020	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
E6C72_08025	COG3199	ATP-NAD kinase
E6C72_08030	COG0277	FAD linked oxidase domain protein
E6C72_08040	COG1671	Belongs to the UPF0178 family
E6C72_08045	COG0488	(ABC) transporter
E6C72_08075	COG2853	Lipoprotein
E6C72_08085	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
E6C72_08095	COG1410	methionine synthase
E6C72_08095	COG0646	methionine synthase
E6C72_08120	COG3706	GGDEF domain
E6C72_08125	COG2070	2-Nitropropane dioxygenase
E6C72_08130	COG0488	(ABC) transporter
E6C72_08135	COG0583	DNA-binding transcription factor activity
E6C72_08140	COG2814	Major facilitator Superfamily
E6C72_08165	COG0175	sulfate reduction
E6C72_08170	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
E6C72_08170	COG1648	precorrin-2 dehydrogenase activity
E6C72_08180	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
E6C72_08190	COG3108	Peptidase M15
E6C72_08200	COG2202	Pas domain
E6C72_08200	COG2205	protein histidine kinase activity
E6C72_08205	COG4566	intracellular signal transduction
E6C72_08235	COG0243	molybdopterin cofactor binding
E6C72_08240	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
E6C72_08240	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
E6C72_08250	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E6C72_08260	COG0612	Peptidase, M16
E6C72_08290	COG0483	inositol monophosphate 1-phosphatase activity
E6C72_08295	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
E6C72_08310	COG0730	response to heat
E6C72_08315	COG0352	thiamine-phosphate diphosphorylase activity
E6C72_08320	COG1830	Aldolase
E6C72_08340	COG0840	transmembrane signaling receptor activity
E6C72_08370	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
E6C72_08375	COG1692	metallophosphoesterase
E6C72_08380	COG0217	transcriptional regulatory protein
E6C72_08390	COG0632	four-way junction helicase activity
E6C72_08395	COG2255	four-way junction helicase activity
E6C72_08400	COG0824	Thioesterase
E6C72_08410	COG0848	biopolymer transport protein
E6C72_08425	COG2885	chlorophyll binding
E6C72_08435	COG0037	tRNA processing
E6C72_08440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E6C72_08450	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
E6C72_08455	COG1295	ribonuclease BN
E6C72_08475	COG0259	pyridoxamine-phosphate oxidase activity
E6C72_08500	COG0840	transmembrane signaling receptor activity
E6C72_08505	COG2153	protein acetylation
E6C72_08520	COG3685	Protein conserved in bacteria
E6C72_08535	COG4957	zinc ion binding
E6C72_08540	COG0698	ribose 5-phosphate isomerase
E6C72_08545	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
E6C72_08550	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
E6C72_08555	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
E6C72_08570	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
E6C72_08575	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
E6C72_08580	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
E6C72_08580	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
E6C72_08590	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E6C72_08590	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E6C72_08610	COG0333	Belongs to the bacterial ribosomal protein bL32 family
E6C72_08615	COG0416	fatty acid biosynthetic process
E6C72_08620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
E6C72_08640	COG1764	response to oxidative stress
E6C72_08645	COG1846	Transcriptional regulator
E6C72_08650	COG0456	acetyltransferase
E6C72_08660	COG2890	protein-(glutamine-N5) methyltransferase activity
E6C72_08665	COG1393	Belongs to the ArsC family
E6C72_08670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E6C72_08680	COG1403	HNH endonuclease
E6C72_08705	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E6C72_08750	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
E6C72_08775	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
E6C72_08785	COG3108	Peptidase M15
E6C72_08810	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
E6C72_08815	COG0511	ligase activity, forming carbon-carbon bonds
E6C72_08820	COG0439	Biotin carboxylase
E6C72_08825	COG0840	transmembrane signaling receptor activity
E6C72_08830	COG4251	negative regulation of phosphorylation
E6C72_08835	COG4251	negative regulation of phosphorylation
E6C72_08840	COG0784	Response regulator, receiver
E6C72_08845	COG0745	RESPONSE REGULATOR receiver
E6C72_08845	COG3706	GGDEF domain
E6C72_08855	COG0745	RESPONSE REGULATOR receiver
E6C72_08875	COG0432	Pfam Uncharacterised protein family UPF0047
E6C72_08880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E6C72_08890	COG2205	protein histidine kinase activity
E6C72_08895	COG0628	permease
E6C72_08905	COG0616	signal peptide processing
E6C72_08915	COG0745	RESPONSE REGULATOR receiver
E6C72_08925	COG0436	Aminotransferase
E6C72_08935	COG1494	fructose-1,6-bisphosphatase
E6C72_08955	COG1324	tolerance protein
E6C72_08960	COG0303	'Molybdopterin
E6C72_08965	COG0583	DNA-binding transcription factor activity
E6C72_08980	COG2373	Large extracellular alpha-helical protein
E6C72_08985	COG4953	penicillin-binding protein 1C
E6C72_09000	COG2132	Multicopper oxidase
E6C72_09010	COG1914	H( )-stimulated, divalent metal cation uptake system
E6C72_09055	COG0518	GMP synthase (glutamine-hydrolyzing) activity
E6C72_09055	COG0519	Catalyzes the synthesis of GMP from XMP
E6C72_09060	COG1247	-acetyltransferase
E6C72_09070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E6C72_09075	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
E6C72_09085	COG1758	RNA polymerase activity
E6C72_09100	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
E6C72_09105	COG0736	holo-[acyl-carrier-protein] synthase activity
E6C72_09110	COG0681	Belongs to the peptidase S26 family
E6C72_09115	COG0571	ribonuclease III activity
E6C72_09120	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
E6C72_09135	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
E6C72_09145	COG1752	Esterase of the alpha-beta hydrolase superfamily
E6C72_09170	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
E6C72_09180	COG1338	Plays a role in the flagellum-specific transport system
E6C72_09195	COG2257	FlhB HrpN YscU SpaS Family
E6C72_09200	COG1815	bacterial-type flagellum-dependent cell motility
E6C72_09205	COG1558	bacterial-type flagellum-dependent cell motility
E6C72_09210	COG1677	Flagellar hook-basal body complex protein FliE
E6C72_09225	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
E6C72_09260	COG2010	Cytochrome c
E6C72_09275	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
E6C72_09285	COG2076	Multidrug Resistance protein
E6C72_09290	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
E6C72_09305	COG0312	modulator of DNA gyrase
E6C72_09315	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
E6C72_09320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
E6C72_09325	COG0109	protoheme IX farnesyltransferase activity
E6C72_09335	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
E6C72_09340	COG1845	cytochrome c oxidase, subunit III
E6C72_09350	COG3346	SURF1 family
E6C72_09360	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E6C72_09365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E6C72_09370	COG3237	CsbD-like
E6C72_09385	COG1742	UPF0060 membrane protein
E6C72_09395	COG5001	Diguanylate cyclase
E6C72_09400	COG1840	ABC-type Fe3 transport system, periplasmic component
E6C72_09405	COG3842	ATPase activity
E6C72_09410	COG1132	(ABC) transporter
E6C72_09415	COG1752	Esterase of the alpha-beta hydrolase superfamily
E6C72_09435	COG1178	ABC-type Fe3 transport system permease component
E6C72_09455	COG2226	methyltransferase
E6C72_09470	COG1196	nuclear chromosome segregation
E6C72_09470	COG0741	lytic transglycosylase activity
E6C72_09470	COG0739	heme binding
E6C72_09480	COG5487	UPF0391 membrane protein
E6C72_09490	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E6C72_09495	COG1765	OsmC-like protein
E6C72_09515	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
E6C72_09520	COG0728	peptidoglycan biosynthetic process
E6C72_09525	COG2205	protein histidine kinase activity
E6C72_09530	COG4191	Histidine kinase
E6C72_09545	COG2086	electron transfer activity
E6C72_09555	COG0789	Transcriptional regulator
E6C72_09560	COG0318	PFAM AMP-dependent synthetase and ligase
E6C72_09580	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
E6C72_09585	COG1360	Flagellar Motor Protein
E6C72_09590	COG2308	Evidence 4 Homologs of previously reported genes of
E6C72_09630	COG0626	cystathionine gamma-synthase activity
E6C72_09635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E6C72_09640	COG4597	amino acid ABC transporter
E6C72_09645	COG0765	amino acid transport
E6C72_09650	COG1126	abc transporter atp-binding protein
E6C72_09655	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
E6C72_09670	COG0454	-acetyltransferase
E6C72_09670	COG0456	acetyltransferase
E6C72_09675	COG2897	thiosulfate sulfurtransferase activity
E6C72_09690	COG0494	nUDIX hydrolase
E6C72_09695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E6C72_09725	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
E6C72_09735	COG1538	Outer membrane efflux protein
E6C72_09745	COG0525	valine-tRNA ligase activity
E6C72_09755	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
E6C72_09760	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
E6C72_09770	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
E6C72_09775	COG0628	permease
E6C72_09785	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_09790	COG1846	Transcriptional regulator
E6C72_09830	COG1396	sequence-specific DNA binding
E6C72_09870	COG0704	Plays a role in the regulation of phosphate uptake
E6C72_09885	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
E6C72_09890	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
E6C72_09895	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
E6C72_09915	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
E6C72_09920	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
E6C72_09955	COG1366	Belongs to the anti-sigma-factor antagonist family
E6C72_09960	COG2208	phosphoserine phosphatase activity
E6C72_09970	COG0784	Response regulator, receiver
E6C72_09970	COG5002	protein histidine kinase activity
E6C72_09970	COG2205	protein histidine kinase activity
E6C72_09975	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
E6C72_10000	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_10005	COG0443	Heat shock 70 kDa protein
E6C72_10010	COG0489	protein tyrosine kinase activity
E6C72_10015	COG0330	HflC and HflK could
E6C72_10020	COG0330	HflC and HflK could
E6C72_10025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E6C72_10035	COG2197	response regulator
E6C72_10040	COG2205	protein histidine kinase activity
E6C72_10045	COG0745	RESPONSE REGULATOR receiver
E6C72_10055	COG1846	Transcriptional regulator
E6C72_10065	COG0149	triose-phosphate isomerase activity
E6C72_10100	COG1566	PFAM secretion protein HlyD family protein
E6C72_10105	COG1136	(ABC) transporter
E6C72_10110	COG1136	(ABC) transporter
E6C72_10110	COG0577	efflux transmembrane transporter activity
E6C72_10140	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
E6C72_10145	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
E6C72_10150	COG0534	Mate efflux family protein
E6C72_10165	COG0741	lytic transglycosylase activity
E6C72_10170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E6C72_10175	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
E6C72_10180	COG2813	Specifically methylates the guanine in position
E6C72_10185	COG0667	Aldo Keto reductase
E6C72_10200	COG1881	PFAM PEBP family protein
E6C72_10205	COG0113	porphobilinogen synthase activity
E6C72_10220	COG1024	Enoyl-CoA hydratase
E6C72_10225	COG1846	Transcriptional regulator
E6C72_10240	COG0559	Belongs to the binding-protein-dependent transport system permease family
E6C72_10255	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
E6C72_10280	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_10285	COG0840	transmembrane signaling receptor activity
E6C72_10285	COG2972	Histidine kinase
E6C72_10295	COG0456	acetyltransferase
E6C72_10300	COG0058	SHG alpha-glucan phosphorylase activity
E6C72_10305	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E6C72_10315	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
E6C72_10320	COG4191	Histidine kinase
E6C72_10325	COG0745	RESPONSE REGULATOR receiver
E6C72_10335	COG2308	Evidence 4 Homologs of previously reported genes of
E6C72_10335	COG2307	Protein conserved in bacteria
E6C72_10365	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
E6C72_10395	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
E6C72_10410	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
E6C72_10415	COG2814	Major facilitator Superfamily
E6C72_10420	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
E6C72_10430	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
E6C72_10450	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E6C72_10460	COG3737	Protein of unknown function (DUF498/DUF598)
E6C72_10475	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
E6C72_10480	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
E6C72_10485	COG1562	ergosterol biosynthetic process
E6C72_10490	COG1562	ergosterol biosynthetic process
E6C72_10510	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
E6C72_10520	COG2062	phosphohistidine phosphatase, SixA
E6C72_10525	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
E6C72_10535	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_10545	COG0617	tRNA 3'-terminal CCA addition
E6C72_10560	COG0714	Associated with various cellular activities
E6C72_10590	COG2226	methyltransferase
E6C72_10595	COG2814	Major facilitator Superfamily
E6C72_10600	COG0583	DNA-binding transcription factor activity
E6C72_10605	COG0629	single-stranded DNA binding
E6C72_10635	COG0123	including yeast histone deacetylase and acetoin utilization protein
E6C72_10640	COG1116	anion transmembrane transporter activity
E6C72_10645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E6C72_10650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
E6C72_10660	COG0483	inositol monophosphate 1-phosphatase activity
E6C72_10675	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
E6C72_10680	COG1923	regulation of RNA biosynthetic process
E6C72_10700	COG2204	response regulator
E6C72_10740	COG1942	4-Oxalocrotonate Tautomerase
E6C72_10745	COG2867	negative regulation of translational initiation
E6C72_10750	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
E6C72_10760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E6C72_10770	COG0508	dehydrogenase complex catalyzes the overall conversion of
E6C72_10775	COG0508	dehydrogenase complex catalyzes the overall conversion of
E6C72_10775	COG0022	dehydrogenase e1 component
E6C72_10780	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
E6C72_10800	COG4149	molybdate abc transporter
E6C72_10805	COG0725	ABC transporter, periplasmic molybdate-binding protein
E6C72_10810	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E6C72_10815	COG2261	transglycosylase associated protein
E6C72_10830	COG2135	peptidase activity
E6C72_10840	COG2199	diguanylate cyclase activity
E6C72_10840	COG2200	EAL domain
E6C72_10840	COG3287	FIST C domain
E6C72_10850	COG1218	3'(2'),5'-bisphosphate nucleotidase
E6C72_10855	COG2833	Protein of unknown function (DUF455)
E6C72_10860	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
E6C72_10865	COG0328	RNA-DNA hybrid ribonuclease activity
E6C72_10870	COG0678	peroxiredoxin activity
E6C72_10875	COG2824	Alkylphosphonate utilization operon protein PhnA
E6C72_10880	COG4232	protein-disulfide reductase activity
E6C72_10885	COG1678	Uncharacterized ACR, COG1678
E6C72_10890	COG0314	molybdopterin synthase activity
E6C72_10895	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
E6C72_10905	COG0546	phosphoglycolate phosphatase activity
E6C72_10910	COG1763	Mo-molybdopterin cofactor biosynthetic process
E6C72_10915	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
E6C72_10925	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_10950	COG4120	Belongs to the binding-protein-dependent transport system permease family
E6C72_10955	COG0410	ABC transporter
E6C72_10990	COG0583	DNA-binding transcription factor activity
E6C72_10995	COG0540	Belongs to the ATCase OTCase family
E6C72_11000	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
E6C72_11010	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E6C72_11025	COG0776	regulation of translation
E6C72_11030	COG4957	zinc ion binding
E6C72_11035	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E6C72_11070	COG0741	lytic transglycosylase activity
E6C72_11075	COG0556	nucleotide-excision repair
E6C72_11080	COG2203	Gaf domain
E6C72_11080	COG2199	diguanylate cyclase activity
E6C72_11105	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
E6C72_11110	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
E6C72_11135	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
E6C72_11140	COG1492	cobalamin metabolic process
E6C72_11205	COG0315	cyclic pyranopterin monophosphate synthase activity
E6C72_11210	COG0303	'Molybdopterin
E6C72_11215	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
E6C72_11220	COG2333	competence protein COMEC
E6C72_11220	COG0658	competence protein
E6C72_11225	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
E6C72_11240	COG4977	sequence-specific DNA binding
E6C72_11250	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
E6C72_11255	COG3494	Protein of unknown function (DUF1009)
E6C72_11260	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
E6C72_11280	COG0750	zinc metalloprotease
E6C72_11285	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
E6C72_11290	COG0575	Belongs to the CDS family
E6C72_11295	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
E6C72_11300	COG0233	cytoplasmic translational termination
E6C72_11305	COG0528	UMP kinase activity
E6C72_11310	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
E6C72_11315	COG0052	Belongs to the universal ribosomal protein uS2 family
E6C72_11320	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
E6C72_11325	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
E6C72_11335	COG4221	oxidoreductase activity
E6C72_11340	COG1561	YicC-like family, N-terminal region
E6C72_11355	COG0840	transmembrane signaling receptor activity
E6C72_11375	COG0513	Belongs to the DEAD box helicase family
E6C72_11400	COG0187	DNA topoisomerase II activity
E6C72_11405	COG1607	acyl-coa hydrolase
E6C72_11415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
E6C72_11420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E6C72_11450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E6C72_11450	COG4191	Histidine kinase
E6C72_11465	COG3437	response regulator, receiver
E6C72_11465	COG0784	Response regulator, receiver
E6C72_11475	COG0140	phosphoribosyl-ATP diphosphatase activity
E6C72_11505	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
E6C72_11510	COG2198	Histidine kinase
E6C72_11510	COG0643	Histidine kinase
E6C72_11515	COG2201	protein-glutamate methylesterase activity
E6C72_11520	COG2201	protein-glutamate methylesterase activity
E6C72_11535	COG0840	transmembrane signaling receptor activity
E6C72_11540	COG0840	transmembrane signaling receptor activity
E6C72_11555	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
E6C72_11560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E6C72_11575	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
E6C72_11585	COG0360	Binds together with S18 to 16S ribosomal RNA
E6C72_11590	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
E6C72_11600	COG0359	binds to the 23S rRNA
E6C72_11610	COG0538	isocitrate dehydrogenase activity
E6C72_11620	COG0330	HflC and HflK could
E6C72_11640	COG1595	DNA-templated transcription, initiation
E6C72_11645	COG0473	3-isopropylmalate dehydrogenase activity
E6C72_11675	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E6C72_11710	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
E6C72_11715	COG4221	oxidoreductase activity
E6C72_11720	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
E6C72_11740	COG0024	Methionine aminopeptidase
E6C72_11750	COG4636	protein conserved in cyanobacteria
E6C72_11760	COG1160	GTP binding
E6C72_11775	COG2197	response regulator
E6C72_11785	COG0840	transmembrane signaling receptor activity
E6C72_11790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E6C72_11845	COG0604	alcohol dehydrogenase
E6C72_11845	COG3321	synthase
E6C72_11845	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_11855	COG0163	prenyltransferase activity
E6C72_11860	COG0288	reversible hydration of carbon dioxide
E6C72_11885	COG0205	6-phosphofructokinase activity
E6C72_11900	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
E6C72_11905	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
E6C72_11910	COG5001	Diguanylate cyclase
E6C72_11930	COG0114	fumarate hydratase activity
E6C72_11955	COG2951	lytic endotransglycosylase activity
E6C72_11965	COG2197	response regulator
E6C72_11980	COG0784	Response regulator, receiver
E6C72_11980	COG4191	Histidine kinase
E6C72_11985	COG3706	GGDEF domain
E6C72_11990	COG4191	Histidine kinase
E6C72_12005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E6C72_12035	COG1366	Belongs to the anti-sigma-factor antagonist family
E6C72_12095	COG0105	UTP biosynthetic process
E6C72_12105	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
E6C72_12115	COG0488	(ABC) transporter
E6C72_12120	COG3932	Exopolysaccharide synthesis, ExoD
E6C72_12125	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
E6C72_12145	COG1686	Belongs to the peptidase S11 family
E6C72_12150	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
E6C72_12155	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
E6C72_12160	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E6C72_12165	COG0084	hydrolase, TatD family'
E6C72_12170	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
E6C72_12170	COG0321	lipoyl(octanoyl) transferase activity
E6C72_12175	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
E6C72_12205	COG1381	Involved in DNA repair and RecF pathway recombination
E6C72_12210	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
E6C72_12235	COG4786	Flagellar basal body rod
E6C72_12240	COG4786	Flagellar basal body rod
E6C72_12250	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
E6C72_12270	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E6C72_12315	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
E6C72_12320	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
E6C72_12330	COG1024	Enoyl-CoA hydratase
E6C72_12340	COG0758	DNA mediated transformation
E6C72_12345	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E6C72_12380	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
E6C72_12395	COG1024	Enoyl-CoA hydratase
E6C72_12400	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
E6C72_12410	COG0745	RESPONSE REGULATOR receiver
E6C72_12410	COG3706	GGDEF domain
E6C72_12420	COG5001	Diguanylate cyclase
E6C72_12420	COG3447	MASE1 domain protein
E6C72_12420	COG5002	protein histidine kinase activity
E6C72_12450	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E6C72_12465	COG1238	metal cluster binding
E6C72_12470	COG0203	ribosomal protein L17
E6C72_12485	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
E6C72_12500	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
E6C72_12505	COG0251	oxidation-reduction process
E6C72_12540	COG2972	Histidine kinase
E6C72_12540	COG0840	transmembrane signaling receptor activity
E6C72_12570	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
E6C72_12570	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
E6C72_12600	COG0154	amidase activity
E6C72_12605	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
E6C72_12620	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
E6C72_12630	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
E6C72_12660	COG0242	peptide deformylase activity
E6C72_12665	COG0828	Belongs to the bacterial ribosomal protein bS21 family
E6C72_12670	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
E6C72_12675	COG1201	RNA secondary structure unwinding
E6C72_12685	COG0415	Belongs to the DNA photolyase family
E6C72_12690	COG0735	belongs to the Fur family
E6C72_12695	COG0523	cobalamin synthesis protein
E6C72_12705	COG0840	transmembrane signaling receptor activity
E6C72_12710	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
E6C72_12725	COG2205	protein histidine kinase activity
E6C72_12730	COG2927	DNA polymerase III (CHI subunit)
E6C72_12735	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
E6C72_12740	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
E6C72_12740	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
E6C72_12755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E6C72_12755	COG0357	Ribosomal RNA small subunit methyltransferase G
E6C72_12760	COG4251	negative regulation of phosphorylation
E6C72_12765	COG0494	nUDIX hydrolase
E6C72_12770	COG0583	DNA-binding transcription factor activity
E6C72_12775	COG0497	DNA recombination
E6C72_12780	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E6C72_12795	COG0745	RESPONSE REGULATOR receiver
E6C72_12800	COG0006	proline dipeptidase activity
E6C72_12810	COG2264	protein methyltransferase activity
E6C72_12820	COG0210	DNA helicase
E6C72_12825	COG2197	response regulator
E6C72_12830	COG2197	response regulator
E6C72_12845	COG1749	Flagellar hook protein flgE
E6C72_12845	COG1749	Flagellar hook protein flgE
E6C72_12860	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
E6C72_12865	COG0366	Alpha amylase catalytic
E6C72_12875	COG0631	protein serine/threonine phosphatase activity
E6C72_12880	COG1558	bacterial-type flagellum-dependent cell motility
E6C72_12905	COG0457	Tetratricopeptide repeat
E6C72_12905	COG0859	PFAM glycosyl transferase family 9
E6C72_12920	COG0457	Tetratricopeptide repeat
E6C72_12920	COG0859	PFAM glycosyl transferase family 9
E6C72_12935	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
E6C72_12940	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_12965	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
E6C72_12970	COG2089	acid synthase
E6C72_12990	COG5002	protein histidine kinase activity
E6C72_13005	COG0588	phosphoglycerate mutase activity
E6C72_13025	COG3693	PFAM glycoside hydrolase, family 10
E6C72_13035	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
E6C72_13040	COG1045	serine acetyltransferase
E6C72_13055	COG3307	-O-antigen
E6C72_13060	COG1216	Glycosyl transferase, family 2
E6C72_13065	COG0438	transferase activity, transferring glycosyl groups
E6C72_13070	COG0438	transferase activity, transferring glycosyl groups
E6C72_13085	COG0318	PFAM AMP-dependent synthetase and ligase
E6C72_13090	COG0367	asparagine synthase
E6C72_13095	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
E6C72_13120	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
E6C72_13125	COG4208	sulfate ABC transporter
E6C72_13135	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
E6C72_13155	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
E6C72_13185	COG2226	methyltransferase
E6C72_13200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E6C72_13210	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
E6C72_13215	COG1846	Transcriptional regulator
E6C72_13225	COG3707	response regulator
E6C72_13235	COG1304	FMN binding
E6C72_13265	COG3833	ABC-type maltose transport systems, permease component
E6C72_13270	COG1840	ABC-type Fe3 transport system, periplasmic component
E6C72_13285	COG1529	Aldehyde oxidase and xanthine dehydrogenase
E6C72_13290	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
E6C72_13295	COG2080	2 iron, 2 sulfur cluster binding
E6C72_13300	COG3791	Glutathione-dependent formaldehyde-activating
E6C72_13315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E6C72_13320	COG0367	asparagine synthase
E6C72_13335	COG1363	Peptidase, m42
E6C72_13340	COG0784	Response regulator, receiver
E6C72_13340	COG5002	protein histidine kinase activity
E6C72_13345	COG0745	RESPONSE REGULATOR receiver
E6C72_13360	COG0840	transmembrane signaling receptor activity
E6C72_13370	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
E6C72_13380	COG1012	belongs to the aldehyde dehydrogenase family
E6C72_13380	COG2030	dehydratase
E6C72_13395	COG2198	Histidine kinase
E6C72_13395	COG5002	protein histidine kinase activity
E6C72_13395	COG0784	Response regulator, receiver
E6C72_13410	COG1253	flavin adenine dinucleotide binding
E6C72_13425	COG2205	protein histidine kinase activity
E6C72_13425	COG0784	Response regulator, receiver
E6C72_13425	COG2198	Histidine kinase
E6C72_13435	COG1396	sequence-specific DNA binding
E6C72_13440	COG1766	The M ring may be actively involved in energy transduction
E6C72_13450	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E6C72_13455	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
E6C72_13460	COG2204	response regulator
E6C72_13465	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
E6C72_13475	COG0455	bacterial-type flagellum organization
E6C72_13515	COG0745	RESPONSE REGULATOR receiver
E6C72_13520	COG2205	protein histidine kinase activity
E6C72_13545	COG0469	pyruvate kinase activity
E6C72_13550	COG3437	response regulator, receiver
E6C72_13550	COG0784	Response regulator, receiver
E6C72_13555	COG5001	Diguanylate cyclase
E6C72_13565	COG1609	Transcriptional regulator
E6C72_13570	COG3842	ATPase activity
E6C72_13585	COG1177	transmembrane transport
E6C72_13590	COG1234	tRNA 3'-trailer cleavage
E6C72_13595	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
E6C72_13600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E6C72_13605	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
E6C72_13610	COG0583	DNA-binding transcription factor activity
E6C72_13620	COG3842	ATPase activity
E6C72_13625	COG1840	ABC-type Fe3 transport system, periplasmic component
E6C72_13635	COG1609	Transcriptional regulator
E6C72_13645	COG1176	ABC-type spermidine putrescine transport system, permease component I
E6C72_13650	COG1177	transmembrane transport
E6C72_13655	COG3842	ATPase activity
E6C72_13660	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
E6C72_13665	COG1840	ABC-type Fe3 transport system, periplasmic component
E6C72_13670	COG1176	ABC-type spermidine putrescine transport system, permease component I
E6C72_13675	COG0673	inositol 2-dehydrogenase activity
E6C72_13690	COG0395	ABC-type sugar transport system, permease component
E6C72_13715	COG0745	RESPONSE REGULATOR receiver
E6C72_13725	COG1063	alcohol dehydrogenase
E6C72_13730	COG2133	pyrroloquinoline quinone binding
E6C72_13760	COG0798	PFAM Bile acid sodium symporter
E6C72_13765	COG1454	alcohol dehydrogenase
E6C72_13765	COG1012	belongs to the aldehyde dehydrogenase family
E6C72_13790	COG1172	Belongs to the binding-protein-dependent transport system permease family
E6C72_13795	COG1129	ABC transporter
E6C72_13800	COG3718	enzyme involved in inositol metabolism
E6C72_13810	COG1737	Transcriptional regulator
E6C72_13830	COG3962	Belongs to the TPP enzyme family
E6C72_13835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E6C72_13840	COG1082	Xylose isomerase domain protein TIM barrel
E6C72_13850	COG0673	inositol 2-dehydrogenase activity
E6C72_13855	COG1609	Transcriptional regulator
E6C72_13860	COG2814	Major facilitator Superfamily
E6C72_13875	COG5001	Diguanylate cyclase
E6C72_13875	COG4251	negative regulation of phosphorylation
E6C72_13875	COG3706	GGDEF domain
E6C72_13875	COG2203	Gaf domain
E6C72_13880	COG5383	Protein conserved in bacteria
E6C72_13895	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
E6C72_13925	COG0601	transmembrane transport
E6C72_13935	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
E6C72_13950	COG0444	Belongs to the ABC transporter superfamily
E6C72_13980	COG1446	asparaginase
E6C72_13985	COG2362	D-Aminopeptidase
E6C72_13995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E6C72_14000	COG0601	transmembrane transport
E6C72_14010	COG0747	negative chemotaxis
E6C72_14015	COG4172	Belongs to the ABC transporter superfamily
E6C72_14030	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E6C72_14045	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
E6C72_14050	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
E6C72_14055	COG1984	allophanate hydrolase subunit 2
E6C72_14060	COG3706	GGDEF domain
E6C72_14060	COG0745	RESPONSE REGULATOR receiver
E6C72_14070	COG0246	Mannitol dehydrogenase
E6C72_14075	COG1312	Catalyzes the dehydration of D-mannonate
E6C72_14095	COG3852	Histidine kinase
E6C72_14100	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
E6C72_14115	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E6C72_14125	COG0728	peptidoglycan biosynthetic process
E6C72_14130	COG0596	Alpha beta hydrolase
E6C72_14135	COG0148	phosphopyruvate hydratase activity
E6C72_14150	COG0678	peroxiredoxin activity
E6C72_14160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E6C72_14170	COG3243	poly(R)-hydroxyalkanoic acid synthase
E6C72_14175	COG3064	Membrane
E6C72_14175	COG4991	sh3 domain protein
E6C72_14175	COG0515	serine threonine protein kinase
E6C72_14225	COG0559	Belongs to the binding-protein-dependent transport system permease family
E6C72_14240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E6C72_14245	COG1309	transcriptional regulator
E6C72_14250	COG0840	transmembrane signaling receptor activity
E6C72_14260	COG2205	protein histidine kinase activity
E6C72_14285	COG1024	Enoyl-CoA hydratase
E6C72_14290	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
E6C72_14295	COG1960	acyl-CoA dehydrogenase activity
E6C72_14300	COG0183	Belongs to the thiolase family
E6C72_14305	COG1960	acyl-CoA dehydrogenase activity
E6C72_14330	COG3135	benzoate transporter
E6C72_14335	COG1802	Transcriptional regulator
E6C72_14340	COG2205	protein histidine kinase activity
E6C72_14340	COG0784	Response regulator, receiver
E6C72_14365	COG4585	Histidine kinase
E6C72_14370	COG2197	response regulator
E6C72_14405	COG2814	Major facilitator Superfamily
E6C72_14430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E6C72_14440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E6C72_14455	COG0583	DNA-binding transcription factor activity
E6C72_14460	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
E6C72_14480	COG3254	rhamnose metabolic process
E6C72_14490	COG1172	Belongs to the binding-protein-dependent transport system permease family
E6C72_14495	COG1129	ABC transporter
E6C72_14510	COG3347	Dehydrogenase
E6C72_14510	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_14515	COG4952	isomerase
E6C72_14570	COG2205	protein histidine kinase activity
E6C72_14570	COG0784	Response regulator, receiver
E6C72_14580	COG3012	SEC-C Motif Domain Protein
E6C72_14590	COG1749	Flagellar hook protein flgE
E6C72_14590	COG1749	Flagellar hook protein flgE
E6C72_14595	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
E6C72_14605	COG2076	Multidrug Resistance protein
E6C72_14610	COG1022	Amp-dependent synthetase and ligase
E6C72_14610	COG3320	Male sterility
E6C72_14620	COG2814	Major facilitator Superfamily
E6C72_14630	COG1609	Transcriptional regulator
E6C72_14655	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E6C72_14660	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
E6C72_14685	COG0671	phosphoesterase, PA-phosphatase related
E6C72_14690	COG2204	response regulator
E6C72_14695	COG4191	Histidine kinase
E6C72_14720	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
E6C72_14770	COG0235	Class ii aldolase
E6C72_14780	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E6C72_14795	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
E6C72_14810	COG3384	dioxygenase
E6C72_14820	COG3971	2-oxopent-4-enoate hydratase activity
E6C72_14830	COG1846	Transcriptional regulator
E6C72_14835	COG1012	belongs to the aldehyde dehydrogenase family
E6C72_14850	COG2205	protein histidine kinase activity
E6C72_14855	COG0745	RESPONSE REGULATOR receiver
E6C72_14865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E6C72_14875	COG0745	RESPONSE REGULATOR receiver
E6C72_14880	COG2205	protein histidine kinase activity
E6C72_14900	COG1116	anion transmembrane transporter activity
E6C72_14925	COG1760	l-serine dehydratase
E6C72_14930	COG0814	amino acid
E6C72_14935	COG3275	phosphorelay sensor kinase activity
E6C72_14940	COG3279	Response regulator of the LytR AlgR family
E6C72_14950	COG0583	DNA-binding transcription factor activity
E6C72_14955	COG0375	protein maturation
E6C72_14960	COG3383	formate dehydrogenase (NAD+) activity
E6C72_14965	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E6C72_14970	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E6C72_14975	COG0651	ATP synthesis coupled electron transport
E6C72_14980	COG0650	Formate hydrogenlyase subunit 4
E6C72_14985	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E6C72_14990	COG4237	Hydrogenase 4 membrane
E6C72_14995	COG0651	ATP synthesis coupled electron transport
E6C72_15000	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
E6C72_15000	COG3261	NADH dehydrogenase
E6C72_15010	COG3260	NADH ubiquinone oxidoreductase 20
E6C72_15020	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E6C72_15025	COG2116	formate transmembrane transporter activity
E6C72_15035	COG0375	protein maturation
E6C72_15095	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
E6C72_15180	COG4974	Belongs to the 'phage' integrase family
E6C72_15190	COG1640	4-alpha-glucanotransferase
E6C72_15205	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
E6C72_15210	COG0366	Alpha amylase catalytic
E6C72_15230	COG2885	chlorophyll binding
E6C72_15230	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
E6C72_15235	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E6C72_15240	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
E6C72_15245	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
E6C72_15250	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
E6C72_15270	COG1262	PFAM Formylglycine-generating sulfatase enzyme
E6C72_15270	COG0515	serine threonine protein kinase
E6C72_15280	COG0583	DNA-binding transcription factor activity
E6C72_15285	COG0625	glutathione transferase activity
E6C72_15295	COG0410	ABC transporter
E6C72_15300	COG0411	ABC transporter
E6C72_15335	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
E6C72_15340	COG3383	formate dehydrogenase (NAD+) activity
E6C72_15355	COG0583	DNA-binding transcription factor activity
E6C72_15390	COG0784	Response regulator, receiver
E6C72_15390	COG2205	protein histidine kinase activity
E6C72_15390	COG5002	protein histidine kinase activity
E6C72_15400	COG0747	negative chemotaxis
E6C72_15405	COG1475	DNA binding
E6C72_15410	COG1192	Involved in chromosome partitioning
E6C72_15445	COG2902	Dehydrogenase
E6C72_15460	COG2814	Major facilitator Superfamily
E6C72_15470	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_15520	COG0667	Aldo Keto reductase
E6C72_15530	COG4221	oxidoreductase activity
E6C72_15535	COG2814	Major facilitator Superfamily
E6C72_15540	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_15570	COG2995	paraquat-inducible protein a
E6C72_15585	COG0745	RESPONSE REGULATOR receiver
E6C72_15590	COG2205	protein histidine kinase activity
E6C72_15600	COG2186	Transcriptional regulator
E6C72_15605	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_15610	COG4948	Mandelate Racemase Muconate Lactonizing
E6C72_15615	COG1063	alcohol dehydrogenase
E6C72_15640	COG1120	ATPase activity
E6C72_15645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E6C72_15650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E6C72_15655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E6C72_15675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E6C72_15680	COG4172	Belongs to the ABC transporter superfamily
E6C72_15695	COG0165	Argininosuccinate lyase
E6C72_15715	COG2079	MmgE PrpD family protein
E6C72_15720	COG0726	polysaccharide deacetylase
E6C72_15730	COG0028	Belongs to the TPP enzyme family
E6C72_15745	COG0765	amino acid transport
E6C72_15760	COG0583	DNA-binding transcription factor activity
E6C72_15765	COG0842	Transport permease protein
E6C72_15770	COG1131	(ABC) transporter
E6C72_15775	COG5000	phosphorelay sensor kinase activity
E6C72_15775	COG5002	protein histidine kinase activity
E6C72_15780	COG0745	RESPONSE REGULATOR receiver
E6C72_15845	COG1116	anion transmembrane transporter activity
E6C72_15850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E6C72_15870	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
E6C72_15875	COG4221	oxidoreductase activity
E6C72_15885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E6C72_15895	COG4521	taurine ABC transporter
E6C72_15900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E6C72_15905	COG0583	DNA-binding transcription factor activity
E6C72_15925	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
E6C72_15930	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E6C72_15935	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E6C72_15955	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E6C72_15965	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
E6C72_15970	COG2814	Major facilitator Superfamily
E6C72_15990	COG4566	intracellular signal transduction
E6C72_15995	COG4566	intracellular signal transduction
E6C72_16010	COG0583	DNA-binding transcription factor activity
E6C72_16015	COG2828	Protein conserved in bacteria
E6C72_16025	COG3384	dioxygenase
E6C72_16030	COG2159	amidohydrolase
E6C72_16045	COG0668	transmembrane transport
E6C72_16065	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
E6C72_16080	COG4166	transmembrane transport
E6C72_16085	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
E6C72_16090	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
E6C72_16095	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
E6C72_16100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E6C72_16130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E6C72_16140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
E6C72_16145	COG1116	anion transmembrane transporter activity
E6C72_16150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E6C72_16155	COG0583	DNA-binding transcription factor activity
E6C72_16175	COG1116	anion transmembrane transporter activity
E6C72_16180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E6C72_16190	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
E6C72_16230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E6C72_16235	COG2188	Transcriptional regulator
E6C72_16240	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
E6C72_16340	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
E6C72_16360	COG0582	viral genome integration into host DNA
E6C72_16365	COG4396	Host-nuclease inhibitor protein Gam
E6C72_16400	COG0740	serine-type endopeptidase activity
E6C72_16490	COG0546	phosphoglycolate phosphatase activity
E6C72_16530	COG0352	thiamine-phosphate diphosphorylase activity
E6C72_16535	COG1802	Transcriptional regulator
E6C72_16540	COG0469	pyruvate kinase activity
E6C72_16550	COG2084	Dehydrogenase
E6C72_16565	COG0517	IMP dehydrogenase activity
E6C72_16590	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E6C72_16600	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
E6C72_16605	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
E6C72_16610	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
E6C72_16615	COG3195	allantoin biosynthetic process
E6C72_16615	COG3648	Uricase
E6C72_16625	COG2351	hydroxyisourate hydrolase activity
E6C72_16630	COG3960	tartronate-semialdehyde synthase activity
E6C72_16640	COG1414	Transcriptional regulator
E6C72_16645	COG1802	Transcriptional regulator
E6C72_16650	COG0028	Belongs to the TPP enzyme family
E6C72_16655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E6C72_16660	COG0045	succinate-CoA ligase (ADP-forming) activity
E6C72_16665	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E6C72_16670	COG1414	Transcriptional regulator
E6C72_16690	COG0860	N-Acetylmuramoyl-L-alanine amidase
E6C72_16705	COG0784	Response regulator, receiver
E6C72_16725	COG0697	spore germination
E6C72_16730	COG0747	negative chemotaxis
E6C72_16735	COG0601	transmembrane transport
E6C72_16740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E6C72_16745	COG0444	Belongs to the ABC transporter superfamily
E6C72_16750	COG4608	Belongs to the ABC transporter superfamily
E6C72_16760	COG1666	GTP binding
E6C72_16785	COG2890	protein-(glutamine-N5) methyltransferase activity
E6C72_16795	COG0142	geranyltranstransferase activity
E6C72_16815	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
E6C72_16825	COG2860	membrane
E6C72_16835	COG2217	Heavy metal translocating P-type atpase
E6C72_16840	COG0789	Transcriptional regulator
E6C72_16855	COG2814	Major facilitator Superfamily
E6C72_16875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
E6C72_16885	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
E6C72_16895	COG0402	S-adenosylhomocysteine deaminase activity
E6C72_16905	COG4603	Belongs to the binding-protein-dependent transport system permease family
E6C72_16925	COG1414	Transcriptional regulator
E6C72_16930	COG3842	ATPase activity
E6C72_16935	COG1176	ABC-type spermidine putrescine transport system, permease component I
E6C72_16940	COG1177	transmembrane transport
E6C72_16955	COG0579	oxidoreductase
E6C72_16965	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
E6C72_16970	COG2223	nitrite transmembrane transporter activity
E6C72_16975	COG3546	catalase activity
E6C72_17000	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
E6C72_17005	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
E6C72_17010	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
E6C72_17015	COG0295	cytidine deaminase activity
E6C72_17030	COG3411	Ferredoxin
E6C72_17045	COG0559	Belongs to the binding-protein-dependent transport system permease family
E6C72_17050	COG0411	ABC transporter
E6C72_17085	COG0740	serine-type endopeptidase activity
E6C72_17090	COG0463	Glycosyl transferase, family 2
E6C72_17105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E6C72_17120	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E6C72_17140	COG0308	aminopeptidase N
E6C72_17165	COG0316	Belongs to the HesB IscA family
E6C72_17170	COG0232	Belongs to the dGTPase family. Type 2 subfamily
E6C72_17185	COG1472	Belongs to the glycosyl hydrolase 3 family
E6C72_17190	COG1994	Peptidase M50
E6C72_17195	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
E6C72_17200	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
E6C72_17205	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E6C72_17210	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E6C72_17215	COG0805	protein transport
E6C72_17240	COG0420	3'-5' exonuclease activity
E6C72_17275	COG0028	Belongs to the TPP enzyme family
E6C72_17280	COG0745	RESPONSE REGULATOR receiver
E6C72_17290	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
E6C72_17295	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
E6C72_17300	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
E6C72_17315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E6C72_17320	COG2342	PFAM TM1410 hypothetical-related protein
E6C72_17355	COG0297	glycogen (starch) synthase activity
E6C72_17375	COG3106	COG3106 Predicted ATPase
E6C72_17380	COG3768	UPF0283 membrane protein
E6C72_17390	COG1741	Belongs to the pirin family
E6C72_17395	COG2205	protein histidine kinase activity
E6C72_17400	COG0564	pseudouridine synthase activity
E6C72_17415	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E6C72_17415	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E6C72_17435	COG2271	Major facilitator Superfamily
E6C72_17440	COG1522	sequence-specific DNA binding
E6C72_17485	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E6C72_17485	COG2169	Transcriptional regulator
E6C72_17500	COG1131	(ABC) transporter
E6C72_17555	COG0559	Belongs to the binding-protein-dependent transport system permease family
E6C72_17560	COG1172	Belongs to the binding-protein-dependent transport system permease family
E6C72_17565	COG0411	ABC transporter
E6C72_17570	COG2273	Hydrolase Family 16
E6C72_17575	COG0772	Belongs to the SEDS family
E6C72_17580	COG3706	GGDEF domain
E6C72_17585	COG1309	transcriptional regulator
E6C72_17605	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
E6C72_17610	COG0393	Putative heavy-metal-binding
E6C72_17640	COG1280	lysine exporter protein (LysE YggA)
E6C72_17645	COG2183	response to ionizing radiation
E6C72_17670	COG4251	negative regulation of phosphorylation
E6C72_17675	COG0784	Response regulator, receiver
E6C72_17685	COG0784	Response regulator, receiver
E6C72_17700	COG2847	Copper chaperone PCu(A)C
E6C72_17735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E6C72_17770	COG0280	phosphate acetyltransferase
E6C72_17770	COG0281	malic enzyme
E6C72_17775	COG1301	dicarboxylic acid transport
E6C72_17780	COG4191	Histidine kinase
E6C72_17785	COG2204	response regulator
E6C72_17815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E6C72_17825	COG0765	amino acid transport
E6C72_17830	COG1126	abc transporter atp-binding protein
E6C72_17835	COG2079	MmgE PrpD family protein
E6C72_17845	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
E6C72_17875	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E6C72_17885	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_17900	COG1012	belongs to the aldehyde dehydrogenase family
E6C72_17905	COG0583	DNA-binding transcription factor activity
E6C72_17910	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_17920	COG3181	Tripartite tricarboxylate transporter family receptor
E6C72_17950	COG1064	alcohol dehydrogenase
E6C72_17995	COG0583	DNA-binding transcription factor activity
E6C72_18000	COG0583	DNA-binding transcription factor activity
E6C72_18005	COG0473	3-isopropylmalate dehydrogenase activity
E6C72_18030	COG1320	monovalent cation:proton antiporter activity
E6C72_18035	COG2212	antiporter activity
E6C72_18040	COG1863	multisubunit Na H antiporter MnhE subunit
E6C72_18045	COG0651	ATP synthesis coupled electron transport
E6C72_18050	COG1006	Multisubunit Na H antiporter MnhC subunit
E6C72_18055	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E6C72_18055	COG2111	Na H antiporter
E6C72_18060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E6C72_18070	COG4191	Histidine kinase
E6C72_18075	COG4566	intracellular signal transduction
E6C72_18085	COG1760	l-serine dehydratase
E6C72_18090	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
E6C72_18100	COG0404	The glycine cleavage system catalyzes the degradation of glycine
E6C72_18100	COG0446	pyridine nucleotide-disulphide oxidoreductase
E6C72_18140	COG4175	Glycine betaine
E6C72_18145	COG2113	Glycine betaine
E6C72_18165	COG1902	pentaerythritol trinitrate reductase activity
E6C72_18165	COG0446	pyridine nucleotide-disulphide oxidoreductase
E6C72_18170	COG2181	nitrate reductase activity
E6C72_18170	COG0247	lactate metabolic process
E6C72_18185	COG4175	Glycine betaine
E6C72_18190	COG4176	ABC-type proline glycine betaine transport system permease component
E6C72_18210	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E6C72_18225	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
E6C72_18230	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
E6C72_18240	COG0189	ligase activity
E6C72_18245	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
E6C72_18255	COG0702	epimerase
E6C72_18265	COG1029	Formylmethanofuran dehydrogenase, subunit B
E6C72_18270	COG1229	Formylmethanofuran dehydrogenase subunit A
E6C72_18275	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
E6C72_18315	COG1891	lyase activity
E6C72_18320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E6C72_18330	COG2807	transmembrane transport
E6C72_18335	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
E6C72_18340	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
E6C72_18350	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
E6C72_18355	COG1609	Transcriptional regulator
E6C72_18360	COG0583	DNA-binding transcription factor activity
E6C72_18365	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_18370	COG3959	Transketolase, thiamine diphosphate binding domain
E6C72_18375	COG3958	Transketolase
E6C72_18380	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
E6C72_18390	COG2084	Dehydrogenase
E6C72_18400	COG1840	ABC-type Fe3 transport system, periplasmic component
E6C72_18415	COG4191	Histidine kinase
E6C72_18415	COG0784	Response regulator, receiver
E6C72_18420	COG0840	transmembrane signaling receptor activity
E6C72_18430	COG0183	Belongs to the thiolase family
E6C72_18435	COG2031	fatty acid transporter
E6C72_18440	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
E6C72_18445	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
E6C72_18450	COG2204	response regulator
E6C72_18455	COG3852	Histidine kinase
E6C72_18500	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
E6C72_18510	COG1737	Transcriptional regulator
E6C72_18540	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
E6C72_18560	COG1335	isochorismatase
E6C72_18565	COG1732	Glycine betaine
E6C72_18570	COG1174	glycine betaine transport
E6C72_18575	COG1125	glycine betaine transport
E6C72_18580	COG1174	glycine betaine transport
E6C72_18595	COG3008	intermembrane lipid transfer
E6C72_18600	COG2995	paraquat-inducible protein a
E6C72_18605	COG2188	Transcriptional regulator
E6C72_18615	COG0765	amino acid transport
E6C72_18620	COG0765	amino acid transport
E6C72_18625	COG1126	abc transporter atp-binding protein
E6C72_18630	COG2226	methyltransferase
E6C72_18635	COG1122	ATPase activity
E6C72_18640	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
E6C72_18645	COG1268	BioY protein
E6C72_18650	COG0318	PFAM AMP-dependent synthetase and ligase
E6C72_18670	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
E6C72_18700	COG5002	protein histidine kinase activity
E6C72_18700	COG0784	Response regulator, receiver
E6C72_18710	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
E6C72_18715	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
E6C72_18735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E6C72_18740	COG0765	amino acid transport
E6C72_18745	COG1126	abc transporter atp-binding protein
E6C72_18760	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
E6C72_18770	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
E6C72_18785	COG0123	including yeast histone deacetylase and acetoin utilization protein
E6C72_18800	COG0640	Transcriptional regulator
E6C72_18805	COG2363	Small membrane protein
E6C72_18850	COG0697	spore germination
E6C72_18865	COG0028	Belongs to the TPP enzyme family
E6C72_18870	COG1012	belongs to the aldehyde dehydrogenase family
E6C72_18895	COG1755	Isoprenylcysteine carboxyl methyltransferase
E6C72_18900	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
E6C72_18920	COG0356	it plays a direct role in the translocation of protons across the membrane
E6C72_18930	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
E6C72_18935	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
E6C72_18940	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
E6C72_18950	COG1529	Aldehyde oxidase and xanthine dehydrogenase
E6C72_18955	COG2080	2 iron, 2 sulfur cluster binding
E6C72_18965	COG1294	oxidase, subunit
E6C72_18970	COG1271	oxidase subunit
E6C72_19000	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
E6C72_19010	COG0745	RESPONSE REGULATOR receiver
E6C72_19035	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
E6C72_19040	COG0408	coproporphyrinogen oxidase activity
E6C72_19070	COG0435	Glutathione S-transferase
E6C72_19075	COG0655	NAD(P)H dehydrogenase (quinone) activity
E6C72_19080	COG0583	DNA-binding transcription factor activity
E6C72_19105	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_19110	COG0542	response to heat
E6C72_19175	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
E6C72_19205	COG0745	RESPONSE REGULATOR receiver
E6C72_19215	COG5002	protein histidine kinase activity
E6C72_19235	COG2863	cytochrome
E6C72_19270	COG1104	cysteine desulfurase activity
E6C72_19280	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
E6C72_19290	COG1984	allophanate hydrolase subunit 2
E6C72_19295	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
E6C72_19305	COG4336	lyase activity
E6C72_19310	COG0410	ABC transporter
E6C72_19315	COG0411	ABC transporter
E6C72_19375	COG2986	histidine ammonia-lyase
E6C72_19380	COG0402	S-adenosylhomocysteine deaminase activity
E6C72_19385	COG1228	amidohydrolase
E6C72_19390	COG2188	Transcriptional regulator
E6C72_19395	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
E6C72_19400	COG2723	6-phospho-beta-galactosidase activity
E6C72_19410	COG1196	nuclear chromosome segregation
E6C72_19410	COG0741	lytic transglycosylase activity
E6C72_19410	COG0739	heme binding
E6C72_19425	COG0583	DNA-binding transcription factor activity
E6C72_19445	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
E6C72_19450	COG3842	ATPase activity
E6C72_19460	COG1176	ABC-type spermidine putrescine transport system, permease component I
E6C72_19470	COG1396	sequence-specific DNA binding
E6C72_19470	COG1917	Cupin 2, conserved barrel domain protein
E6C72_19475	COG1012	belongs to the aldehyde dehydrogenase family
E6C72_19485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E6C72_19525	COG3273	potassium ion transport
E6C72_19525	COG0471	metal ion transport
E6C72_19555	COG2205	protein histidine kinase activity
E6C72_19555	COG2202	Pas domain
E6C72_19560	COG2373	Large extracellular alpha-helical protein
E6C72_19575	COG0183	Belongs to the thiolase family
E6C72_19580	COG1024	Enoyl-CoA hydratase
E6C72_19580	COG1250	3-hydroxyacyl-CoA dehydrogenase
E6C72_19585	COG1960	acyl-CoA dehydrogenase activity
E6C72_19590	COG2197	response regulator
E6C72_19595	COG0516	GMP reductase activity
E6C72_19595	COG0517	IMP dehydrogenase activity
E6C72_19600	COG3047	cAMP biosynthetic process
E6C72_19630	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E6C72_19635	COG1196	nuclear chromosome segregation
E6C72_19645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E6C72_19650	COG0174	glutamine synthetase
E6C72_19660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E6C72_19665	COG0765	amino acid transport
E6C72_19670	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
E6C72_19670	COG0546	phosphoglycolate phosphatase activity
E6C72_19675	COG2076	Multidrug Resistance protein
E6C72_19685	COG3842	ATPase activity
E6C72_19690	COG1176	ABC-type spermidine putrescine transport system, permease component I
E6C72_19695	COG1177	transmembrane transport
E6C72_19700	COG3119	arylsulfatase activity
E6C72_19720	COG3706	GGDEF domain
E6C72_19720	COG0745	RESPONSE REGULATOR receiver
E6C72_19725	COG2205	protein histidine kinase activity
E6C72_19755	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E6C72_19755	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E6C72_19760	COG0243	molybdopterin cofactor binding
E6C72_19765	COG2201	protein-glutamate methylesterase activity
E6C72_19775	COG5002	protein histidine kinase activity
E6C72_19780	COG2197	response regulator
E6C72_19785	COG0827	DNA restriction-modification system
E6C72_19790	COG0827	DNA restriction-modification system
E6C72_19805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E6C72_19825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E6C72_19835	COG2271	Major facilitator Superfamily
E6C72_19840	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
E6C72_19840	COG0674	pyruvate-flavodoxin oxidoreductase activity
E6C72_19840	COG1013	pyruvate-flavodoxin oxidoreductase activity
E6C72_19845	COG0246	Mannitol dehydrogenase
E6C72_19855	COG1609	Transcriptional regulator
E6C72_19870	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E6C72_19875	COG1882	Formate acetyltransferase
E6C72_19890	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
E6C72_19900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E6C72_19905	COG1755	Isoprenylcysteine carboxyl methyltransferase
E6C72_19910	COG0800	Aldolase
E6C72_19915	COG3734	2-keto-3-deoxy-galactonokinase
E6C72_19920	COG1414	Transcriptional regulator
E6C72_19940	COG1741	Belongs to the pirin family
E6C72_19945	COG0316	Belongs to the HesB IscA family
E6C72_19950	COG2151	metal-sulfur cluster biosynthetic enzyme
E6C72_19955	COG0822	iron-sulfur transferase activity
E6C72_19960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
E6C72_19965	COG0719	Fe-S assembly protein
E6C72_19970	COG0396	ATPase activity
E6C72_19975	COG0719	Fe-S assembly protein
E6C72_20025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E6C72_20030	COG1959	2 iron, 2 sulfur cluster binding
E6C72_20035	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_20040	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
E6C72_20045	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
E6C72_20055	COG0704	Plays a role in the regulation of phosphate uptake
E6C72_20065	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
E6C72_20115	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
E6C72_20170	COG3459	Glycosyltransferase 36 associated
E6C72_20175	COG3239	Fatty acid desaturase
E6C72_20255	COG2197	response regulator
E6C72_20270	COG1538	Outer membrane efflux protein
E6C72_20280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E6C72_20295	COG2814	Major facilitator Superfamily
E6C72_20305	COG0583	DNA-binding transcription factor activity
E6C72_20310	COG2159	amidohydrolase
E6C72_20315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E6C72_20330	COG0179	Fumarylacetoacetate (FAA) hydrolase
E6C72_20370	COG0625	glutathione transferase activity
E6C72_20395	COG0179	Fumarylacetoacetate (FAA) hydrolase
E6C72_20400	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E6C72_20410	COG2188	Transcriptional regulator
E6C72_20420	COG2267	carboxylic ester hydrolase activity
E6C72_20430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E6C72_20435	COG1012	belongs to the aldehyde dehydrogenase family
E6C72_20450	COG1176	ABC-type spermidine putrescine transport system, permease component I
E6C72_20455	COG0395	ABC-type sugar transport system, permease component
E6C72_20460	COG3842	ATPase activity
E6C72_20475	COG2912	Transglutaminase-like superfamily
E6C72_20490	COG3493	citrate carrier protein
E6C72_20500	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
E6C72_20520	COG3052	prosthetic group binding
E6C72_20525	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
E6C72_20530	COG0281	malic enzyme
E6C72_20530	COG0280	phosphate acetyltransferase
E6C72_20550	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
E6C72_20555	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
E6C72_20560	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
E6C72_20565	COG1982	Orn Lys Arg decarboxylase major
E6C72_20620	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
E6C72_20665	COG1250	3-hydroxyacyl-CoA dehydrogenase
E6C72_20665	COG1024	Enoyl-CoA hydratase
E6C72_20670	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_20680	COG3806	Anti-sigma factor
E6C72_20685	COG1595	DNA-templated transcription, initiation
E6C72_20695	COG1024	Enoyl-CoA hydratase
E6C72_20705	COG4176	ABC-type proline glycine betaine transport system permease component
E6C72_20710	COG1309	transcriptional regulator
E6C72_20720	COG4191	Histidine kinase
E6C72_20720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E6C72_20725	COG0747	negative chemotaxis
E6C72_20730	COG0784	Response regulator, receiver
E6C72_20730	COG3437	response regulator, receiver
E6C72_20735	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
E6C72_20760	COG0737	Belongs to the 5'-nucleotidase family
E6C72_20765	COG0505	Belongs to the CarA family
E6C72_20770	COG2068	MobA-Related Protein
E6C72_20775	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
E6C72_20850	COG3437	response regulator, receiver
E6C72_20855	COG3012	SEC-C Motif Domain Protein
E6C72_20865	COG1448	Aminotransferase
E6C72_20875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E6C72_20880	COG0583	DNA-binding transcription factor activity
E6C72_20890	COG3483	tryptophan 2,3-dioxygenase activity
E6C72_20910	COG1845	cytochrome c oxidase, subunit III
E6C72_20920	COG3256	nitric oxide reductase
E6C72_20925	COG0714	Associated with various cellular activities
E6C72_20935	COG0521	Mo-molybdopterin cofactor biosynthetic process
E6C72_20945	COG4221	oxidoreductase activity
E6C72_20950	COG1755	Isoprenylcysteine carboxyl methyltransferase
E6C72_20955	COG3424	synthase
E6C72_20965	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
E6C72_20970	COG2272	Belongs to the type-B carboxylesterase lipase family
E6C72_20985	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E6C72_20995	COG2204	response regulator
E6C72_21000	COG0375	protein maturation
E6C72_21040	COG3852	Histidine kinase
E6C72_21055	COG1566	PFAM secretion protein HlyD family protein
E6C72_21070	COG3956	TIGRFAM MazG family protein
E6C72_21115	COG3180	Ammonia monooxygenase
E6C72_21130	COG2132	Multicopper oxidase
E6C72_21150	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
E6C72_21155	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
E6C72_21160	COG0583	DNA-binding transcription factor activity
E6C72_21170	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E6C72_21170	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E6C72_21175	COG1105	Belongs to the carbohydrate kinase PfkB family
E6C72_21180	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
E6C72_21180	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E6C72_21185	COG1609	Transcriptional regulator
E6C72_21205	COG3206	protein involved in exopolysaccharide biosynthesis
E6C72_21205	COG0489	protein tyrosine kinase activity
E6C72_21225	COG0438	transferase activity, transferring glycosyl groups
E6C72_21240	COG0438	transferase activity, transferring glycosyl groups
E6C72_21275	COG2116	formate transmembrane transporter activity
E6C72_21280	COG2815	serine threonine protein kinase
E6C72_21280	COG0515	serine threonine protein kinase
E6C72_21290	COG1131	(ABC) transporter
E6C72_21305	COG0366	Alpha amylase catalytic
E6C72_21315	COG0066	3-isopropylmalate dehydratase activity
E6C72_21320	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
E6C72_21325	COG1053	succinate dehydrogenase
E6C72_21330	COG1335	isochorismatase
E6C72_21365	COG0559	Belongs to the binding-protein-dependent transport system permease family
E6C72_21375	COG2188	Transcriptional regulator
E6C72_21380	COG0668	transmembrane transport
E6C72_21400	COG0583	DNA-binding transcription factor activity
E6C72_21405	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_21420	COG1064	alcohol dehydrogenase
E6C72_21440	COG0459	protein refolding
E6C72_21445	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
E6C72_21460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E6C72_21465	COG1116	anion transmembrane transporter activity
E6C72_21495	COG1464	Belongs to the NlpA lipoprotein family
E6C72_21500	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
E6C72_21505	COG2011	ABC-type metal ion transport system permease component
E6C72_21515	COG1574	metal-dependent hydrolase with the TIM-barrel fold
E6C72_21520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E6C72_21525	COG1116	anion transmembrane transporter activity
E6C72_21540	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
E6C72_21560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E6C72_21565	COG4597	amino acid ABC transporter
E6C72_21570	COG0765	amino acid transport
E6C72_21575	COG1396	sequence-specific DNA binding
E6C72_21585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E6C72_21590	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
E6C72_21600	COG1116	anion transmembrane transporter activity
E6C72_21610	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E6C72_21620	COG3220	belongs to the UPF0276 family
E6C72_21650	COG2205	protein histidine kinase activity
E6C72_21655	COG0745	RESPONSE REGULATOR receiver
E6C72_21660	COG1538	Outer membrane efflux protein
E6C72_21670	COG1136	(ABC) transporter
E6C72_21695	COG1192	Involved in chromosome partitioning
E6C72_21700	COG1475	DNA binding
E6C72_21705	COG3005	denitrification pathway
E6C72_21720	COG3062	negative regulation of establishment of protein localization
E6C72_21730	COG4459	periplasmic nitrate reductase
E6C72_21740	COG4263	nitrous-oxide reductase activity
E6C72_21755	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
E6C72_21765	COG1477	protein flavinylation
E6C72_21770	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E6C72_21815	COG1802	Transcriptional regulator
E6C72_21825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E6C72_21830	COG1116	anion transmembrane transporter activity
E6C72_21835	COG0402	S-adenosylhomocysteine deaminase activity
E6C72_21850	COG1802	Transcriptional regulator
E6C72_21855	COG0154	amidase activity
E6C72_21870	COG1177	transmembrane transport
E6C72_21875	COG1176	ABC-type spermidine putrescine transport system, permease component I
E6C72_21880	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E6C72_21885	COG3842	ATPase activity
E6C72_21890	COG0154	amidase activity
E6C72_21895	COG1802	Transcriptional regulator
E6C72_21900	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
E6C72_21920	COG0318	PFAM AMP-dependent synthetase and ligase
E6C72_21935	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_21965	COG0400	carboxylic ester hydrolase activity
E6C72_21970	COG0435	Glutathione S-transferase
E6C72_21975	COG2353	YceI-like domain
E6C72_21995	COG1609	Transcriptional regulator
E6C72_22000	COG1070	Carbohydrate kinase
E6C72_22005	COG2115	Belongs to the xylose isomerase family
E6C72_22010	COG4213	ABC transporter substrate-binding protein
E6C72_22015	COG4214	carbohydrate transport
E6C72_22020	COG1129	ABC transporter
E6C72_22050	COG4626	Terminase
E6C72_22050	COG1802	Transcriptional regulator
E6C72_22065	COG4191	Histidine kinase
E6C72_22070	COG4566	intracellular signal transduction
E6C72_22075	COG4566	intracellular signal transduction
E6C72_22080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E6C72_22085	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
E6C72_22100	COG1309	transcriptional regulator
E6C72_22115	COG0673	inositol 2-dehydrogenase activity
E6C72_22125	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
E6C72_22135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E6C72_22140	COG1177	transmembrane transport
E6C72_22145	COG1176	ABC-type spermidine putrescine transport system, permease component I
E6C72_22190	COG0251	oxidation-reduction process
E6C72_22195	COG0251	oxidation-reduction process
E6C72_22210	COG1850	ribulose-bisphosphate carboxylase activity
E6C72_22220	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
E6C72_22225	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
E6C72_22230	COG1609	Transcriptional regulator
E6C72_22250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E6C72_22280	COG2233	PERMEase
E6C72_22295	COG1069	ribulokinase activity
E6C72_22300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E6C72_22310	COG1172	Belongs to the binding-protein-dependent transport system permease family
E6C72_22315	COG1172	Belongs to the binding-protein-dependent transport system permease family
E6C72_22320	COG1129	ABC transporter
E6C72_22325	COG1879	ABC-type sugar transport system periplasmic component
E6C72_22330	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
E6C72_22335	COG1349	DNA-binding transcription factor activity
E6C72_22345	COG3383	formate dehydrogenase (NAD+) activity
E6C72_22385	COG1131	(ABC) transporter
E6C72_22390	COG0189	ligase activity
E6C72_22390	COG0569	domain protein
E6C72_22405	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
E6C72_22430	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
E6C72_22435	COG1229	Formylmethanofuran dehydrogenase subunit A
E6C72_22440	COG1029	Formylmethanofuran dehydrogenase, subunit B
E6C72_22450	COG0702	epimerase
E6C72_22455	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
E6C72_22500	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
E6C72_22505	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
E6C72_22540	COG0437	4 iron, 4 sulfur cluster binding
E6C72_22605	COG2186	Transcriptional regulator
E6C72_22610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E6C72_22615	COG2271	Major facilitator Superfamily
E6C72_22620	COG1312	Catalyzes the dehydration of D-mannonate
E6C72_22635	COG2721	sulfolactate sulfo-lyase activity
E6C72_22640	COG2706	6-phosphogluconolactonase activity
E6C72_22645	COG1529	Aldehyde oxidase and xanthine dehydrogenase
E6C72_22645	COG2010	Cytochrome c
E6C72_22650	COG2080	2 iron, 2 sulfur cluster binding
E6C72_22655	COG1846	Transcriptional regulator
E6C72_22660	COG2309	aminopeptidase activity
E6C72_22665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E6C72_22670	COG0596	Alpha beta hydrolase
E6C72_22675	COG3473	Maleate cis-trans isomerase
E6C72_22680	COG1335	isochorismatase
E6C72_22685	COG2271	Major facilitator Superfamily
E6C72_22705	COG1522	sequence-specific DNA binding
E6C72_22730	COG2855	membrane
E6C72_22760	COG0583	DNA-binding transcription factor activity
E6C72_22770	COG1522	sequence-specific DNA binding
E6C72_22775	COG4172	Belongs to the ABC transporter superfamily
E6C72_22780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E6C72_22785	COG0601	transmembrane transport
E6C72_22805	COG0454	-acetyltransferase
E6C72_22815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E6C72_22830	COG1012	belongs to the aldehyde dehydrogenase family
E6C72_22840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E6C72_22860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E6C72_22885	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
E6C72_22890	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
E6C72_22895	COG1802	Transcriptional regulator
E6C72_22900	COG1250	3-hydroxyacyl-CoA dehydrogenase
E6C72_22935	COG3842	ATPase activity
E6C72_22945	COG4154	Belongs to the RbsD FucU family
E6C72_22955	COG2721	sulfolactate sulfo-lyase activity
E6C72_22970	COG1879	ABC-type sugar transport system periplasmic component
E6C72_22975	COG4214	carbohydrate transport
E6C72_22980	COG1129	ABC transporter
E6C72_22985	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_23040	COG0577	efflux transmembrane transporter activity
E6C72_23040	COG1136	(ABC) transporter
E6C72_23120	COG3002	Belongs to the UPF0753 family
E6C72_23125	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E6C72_23155	COG1132	(ABC) transporter
E6C72_23170	COG0641	radical SAM
E6C72_23205	COG2070	2-Nitropropane dioxygenase
E6C72_23205	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
E6C72_23240	COG0251	oxidation-reduction process
E6C72_23285	COG1262	PFAM Formylglycine-generating sulfatase enzyme
E6C72_23295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E6C72_23330	COG3273	potassium ion transport
E6C72_23330	COG0471	metal ion transport
E6C72_23335	COG0517	IMP dehydrogenase activity
E6C72_23350	COG2205	protein histidine kinase activity
E6C72_23350	COG0784	Response regulator, receiver
E6C72_23355	COG3023	N-Acetylmuramoyl-L-alanine amidase
E6C72_23395	COG1914	H( )-stimulated, divalent metal cation uptake system
E6C72_23400	COG1321	iron dependent repressor
E6C72_23410	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
E6C72_23410	COG1918	ferrous iron import across plasma membrane
E6C72_23420	COG2814	Major facilitator Superfamily
E6C72_23435	COG0840	transmembrane signaling receptor activity
E6C72_23440	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
E6C72_23460	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E6C72_23465	COG0375	protein maturation
E6C72_23475	COG2414	aldehyde ferredoxin oxidoreductase
E6C72_23490	COG0651	ATP synthesis coupled electron transport
E6C72_23495	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E6C72_23500	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
E6C72_23510	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E6C72_23515	COG0649	NAD binding
E6C72_23560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E6C72_23605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E6C72_23610	COG0348	domain, Protein
E6C72_23675	COG0025	NhaP-type Na H and K H
E6C72_23690	COG1574	metal-dependent hydrolase with the TIM-barrel fold
E6C72_23700	COG1335	isochorismatase
E6C72_23710	COG0673	inositol 2-dehydrogenase activity
E6C72_23720	COG1879	ABC-type sugar transport system periplasmic component
E6C72_23725	COG1172	Belongs to the binding-protein-dependent transport system permease family
E6C72_23730	COG1129	ABC transporter
E6C72_23735	COG1940	carbohydrate kinase activity
E6C72_23740	COG0840	transmembrane signaling receptor activity
E6C72_23760	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E6C72_23760	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
E6C72_23770	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
E6C72_23775	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E6C72_23780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E6C72_23790	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
E6C72_23795	COG1263	PTS System
E6C72_23795	COG2190	(PTS) system
E6C72_23795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E6C72_23800	COG0840	transmembrane signaling receptor activity
E6C72_23810	COG3842	ATPase activity
E6C72_23820	COG1176	ABC-type spermidine putrescine transport system, permease component I
E6C72_23825	COG0395	ABC-type sugar transport system, permease component
E6C72_23850	COG4191	Histidine kinase
E6C72_23855	COG1301	dicarboxylic acid transport
E6C72_23860	COG1027	Aspartate ammonia-lyase
E6C72_23865	COG2258	MOSC domain
E6C72_23870	COG0840	transmembrane signaling receptor activity
E6C72_23880	COG0604	alcohol dehydrogenase
E6C72_23895	COG0784	Response regulator, receiver
E6C72_23895	COG2205	protein histidine kinase activity
E6C72_23900	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
E6C72_23910	COG0583	DNA-binding transcription factor activity
E6C72_23915	COG0667	Aldo Keto reductase
E6C72_23920	COG2223	nitrite transmembrane transporter activity
E6C72_23930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E6C72_23940	COG4191	Histidine kinase
E6C72_23960	COG0346	lactoylglutathione lyase activity
E6C72_23965	COG3474	cytochrome
E6C72_23975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E6C72_23990	COG0459	protein refolding
E6C72_24020	COG0154	amidase activity
E6C72_24045	COG3119	arylsulfatase activity
E6C72_24055	COG0038	chloride channel
E6C72_24070	COG0765	amino acid transport
E6C72_24085	COG1802	Transcriptional regulator
E6C72_24090	COG0405	Gamma-glutamyltransferase
E6C72_24105	COG3842	ATPase activity
E6C72_24130	COG4615	Cyclic peptide transporter
E6C72_24140	COG0367	asparagine synthase
E6C72_24195	COG2186	Transcriptional regulator
E6C72_24200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E6C72_24210	COG1126	abc transporter atp-binding protein
E6C72_24220	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
E6C72_24235	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
E6C72_24240	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
E6C72_24245	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
E6C72_24250	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
E6C72_24255	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
E6C72_24260	COG1309	transcriptional regulator
E6C72_24310	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_24330	COG0022	dehydrogenase e1 component
E6C72_24335	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
E6C72_24340	COG1172	Belongs to the binding-protein-dependent transport system permease family
E6C72_24360	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
E6C72_24365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E6C72_24375	COG0642	Histidine kinase
E6C72_24380	COG0745	RESPONSE REGULATOR receiver
E6C72_24415	COG1116	anion transmembrane transporter activity
E6C72_24415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
E6C72_24420	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_24430	COG0179	Fumarylacetoacetate (FAA) hydrolase
E6C72_24435	COG1802	Transcriptional regulator
E6C72_24445	COG1213	nucleotidyl transferase
E6C72_24445	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
E6C72_24455	COG4589	Belongs to the CDS family
E6C72_24460	COG0501	Belongs to the peptidase M48B family
E6C72_24475	COG4221	oxidoreductase activity
E6C72_24495	COG1301	dicarboxylic acid transport
E6C72_24500	COG2828	Protein conserved in bacteria
E6C72_24505	COG0583	DNA-binding transcription factor activity
E6C72_24515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E6C72_24515	COG1017	nitric oxide dioxygenase activity
E6C72_24520	COG0625	glutathione transferase activity
E6C72_24530	COG1869	D-ribose catabolic process
E6C72_24540	COG1172	Belongs to the binding-protein-dependent transport system permease family
E6C72_24545	COG1879	ABC-type sugar transport system periplasmic component
E6C72_24550	COG1609	Transcriptional regulator
E6C72_24555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E6C72_24560	COG0659	secondary active sulfate transmembrane transporter activity
E6C72_24570	COG1473	amidohydrolase
E6C72_24575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E6C72_24590	COG0559	Belongs to the binding-protein-dependent transport system permease family
E6C72_24625	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_24630	COG0583	DNA-binding transcription factor activity
E6C72_24645	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_24650	COG1309	transcriptional regulator
E6C72_24655	COG2226	methyltransferase
E6C72_24660	COG2814	Major facilitator Superfamily
E6C72_24665	COG0583	DNA-binding transcription factor activity
E6C72_24670	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
E6C72_24675	COG2186	Transcriptional regulator
E6C72_24685	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
E6C72_24690	COG1454	alcohol dehydrogenase
E6C72_24695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E6C72_24715	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_24720	COG4221	oxidoreductase activity
E6C72_24730	COG0697	spore germination
E6C72_24735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E6C72_24745	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E6C72_24750	COG0235	Class ii aldolase
E6C72_24760	COG0601	transmembrane transport
E6C72_24775	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E6C72_24820	COG3052	prosthetic group binding
E6C72_24840	COG1802	Transcriptional regulator
E6C72_24845	COG5001	Diguanylate cyclase
E6C72_24850	COG2116	formate transmembrane transporter activity
E6C72_24855	COG0148	phosphopyruvate hydratase activity
E6C72_24865	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
E6C72_24875	COG0126	phosphoglycerate kinase activity
E6C72_24910	COG0252	asparaginase activity
E6C72_24930	COG3290	protein histidine kinase activity
E6C72_24930	COG0840	transmembrane signaling receptor activity
E6C72_24935	COG4566	intracellular signal transduction
E6C72_24945	COG2815	serine threonine protein kinase
E6C72_24945	COG0515	serine threonine protein kinase
E6C72_24950	COG4977	sequence-specific DNA binding
E6C72_24970	COG0395	ABC-type sugar transport system, permease component
E6C72_24975	COG1175	transmembrane transport
E6C72_24985	COG1609	Transcriptional regulator
E6C72_25010	COG2814	Major facilitator Superfamily
E6C72_25020	COG1024	Enoyl-CoA hydratase
E6C72_25025	COG1012	belongs to the aldehyde dehydrogenase family
E6C72_25030	COG0840	transmembrane signaling receptor activity
E6C72_25030	COG2203	Gaf domain
E6C72_25040	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
E6C72_25055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E6C72_25070	COG1012	belongs to the aldehyde dehydrogenase family
E6C72_25080	COG2814	Major facilitator Superfamily
E6C72_25095	COG2188	Transcriptional regulator
E6C72_25110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E6C72_25125	COG0431	NADPH-dependent FMN reductase
E6C72_25135	COG0411	ABC transporter
E6C72_25155	COG0410	ABC transporter
E6C72_25165	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
E6C72_25190	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
E6C72_25190	COG0438	transferase activity, transferring glycosyl groups
E6C72_25225	COG0463	Glycosyl transferase, family 2
E6C72_25240	COG0489	protein tyrosine kinase activity
E6C72_25240	COG3206	protein involved in exopolysaccharide biosynthesis
E6C72_25245	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E6C72_25250	COG0438	transferase activity, transferring glycosyl groups
E6C72_25255	COG0438	transferase activity, transferring glycosyl groups
E6C72_25305	COG0242	peptide deformylase activity
E6C72_25335	COG4638	Rieske (2fe-2S)
E6C72_25340	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
E6C72_25345	COG2146	nitrite reductase [NAD(P)H] activity
E6C72_25370	COG1137	ATPase activity
E6C72_25380	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_25405	COG1172	Belongs to the binding-protein-dependent transport system permease family
E6C72_25410	COG1879	ABC-type sugar transport system periplasmic component
E6C72_25460	COG0564	pseudouridine synthase activity
E6C72_25465	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E6C72_25470	COG0454	-acetyltransferase
E6C72_25475	COG1280	lysine exporter protein (LysE YggA)
E6C72_25520	COG0667	Aldo Keto reductase
E6C72_25525	COG1902	pentaerythritol trinitrate reductase activity
E6C72_25535	COG1192	Involved in chromosome partitioning
E6C72_25550	COG1960	acyl-CoA dehydrogenase activity
E6C72_25580	COG3210	domain, Protein
E6C72_25585	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
E6C72_25610	COG0601	transmembrane transport
E6C72_25615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E6C72_25630	COG0438	transferase activity, transferring glycosyl groups
E6C72_25635	COG0588	phosphoglycerate mutase activity
E6C72_25655	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
E6C72_25670	COG1126	abc transporter atp-binding protein
E6C72_25680	COG0765	amino acid transport
E6C72_25685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E6C72_25725	COG0667	Aldo Keto reductase
E6C72_25730	COG2814	Major facilitator Superfamily
E6C72_25740	COG0583	DNA-binding transcription factor activity
E6C72_25755	COG0626	cystathionine gamma-synthase activity
E6C72_25765	COG0583	DNA-binding transcription factor activity
E6C72_25805	COG0318	PFAM AMP-dependent synthetase and ligase
E6C72_25805	COG0204	Acyl-transferase
E6C72_25810	COG2884	Cell division ATP-binding protein ftsE
E6C72_25830	COG2217	Heavy metal translocating P-type atpase
E6C72_25835	COG2610	gluconate transmembrane transporter activity
E6C72_25840	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
E6C72_25845	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
E6C72_25850	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_25885	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
E6C72_25885	COG1672	PFAM Archaeal ATPase
E6C72_25890	COG0129	dihydroxy-acid dehydratase activity
E6C72_25900	COG1566	PFAM secretion protein HlyD family protein
E6C72_25955	COG0564	pseudouridine synthase activity
E6C72_25965	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
E6C72_25975	COG0842	Transport permease protein
E6C72_25980	COG0842	Transport permease protein
E6C72_25980	COG1129	ABC transporter
E6C72_25985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E6C72_25990	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
E6C72_25995	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
E6C72_26000	COG1609	Transcriptional regulator
E6C72_26005	COG3265	gluconokinase activity
E6C72_26015	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
E6C72_26020	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
E6C72_26025	COG0840	transmembrane signaling receptor activity
E6C72_26030	COG3485	protocatechuate 3,4-dioxygenase
E6C72_26035	COG3485	protocatechuate 3,4-dioxygenase
E6C72_26045	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E6C72_26050	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
E6C72_26055	COG0183	Belongs to the thiolase family
E6C72_26060	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
E6C72_26065	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
E6C72_26070	COG0683	leucine binding
E6C72_26100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E6C72_26115	COG1126	abc transporter atp-binding protein
E6C72_26120	COG0765	amino acid transport
E6C72_26125	COG4597	amino acid ABC transporter
E6C72_26130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E6C72_26145	COG2814	Major facilitator Superfamily
E6C72_26160	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
E6C72_26175	COG3634	alkyl hydroperoxide reductase activity
E6C72_26180	COG0450	alkyl hydroperoxide reductase
E6C72_26185	COG0583	DNA-binding transcription factor activity
E6C72_26190	COG0287	Prephenate dehydrogenase
E6C72_26200	COG0693	protein deglycase activity
E6C72_26205	COG2224	Isocitrate lyase
E6C72_26210	COG1396	sequence-specific DNA binding
E6C72_26210	COG3800	Transcriptional regulator
E6C72_26235	COG0306	phosphate transporter
E6C72_26245	COG2205	protein histidine kinase activity
E6C72_26280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E6C72_26285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E6C72_26290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E6C72_26295	COG4774	siderophore transport
E6C72_26320	COG0668	transmembrane transport
E6C72_26330	COG1181	Belongs to the D-alanine--D-alanine ligase family
E6C72_26330	COG2918	glutathione biosynthetic process
E6C72_26340	COG1960	acyl-CoA dehydrogenase activity
E6C72_26345	COG0840	transmembrane signaling receptor activity
E6C72_26360	COG0411	ABC transporter
E6C72_26380	COG0686	Belongs to the AlaDH PNT family
E6C72_26385	COG1522	sequence-specific DNA binding
E6C72_26390	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E6C72_26395	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
E6C72_26405	COG2198	Histidine kinase
E6C72_26405	COG0784	Response regulator, receiver
E6C72_26405	COG2205	protein histidine kinase activity
E6C72_26425	COG1280	lysine exporter protein (LysE YggA)
E6C72_26430	COG0784	Response regulator, receiver
E6C72_26430	COG3437	response regulator, receiver
E6C72_26435	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
E6C72_26445	COG1121	(ABC) transporter
E6C72_26450	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E6C72_26470	COG0347	Belongs to the P(II) protein family
E6C72_26475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E6C72_26490	COG1733	regulation of RNA biosynthetic process
E6C72_26520	COG1045	serine acetyltransferase
E6C72_26555	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
E6C72_26605	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
E6C72_26610	COG1530	ribonuclease E activity
E6C72_26640	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
E6C72_26650	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
E6C72_26670	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
E6C72_26675	COG2011	ABC-type metal ion transport system permease component
E6C72_26680	COG1464	Belongs to the NlpA lipoprotein family
E6C72_26685	COG0859	PFAM glycosyl transferase family 9
E6C72_26685	COG0457	Tetratricopeptide repeat
E6C72_26690	COG2201	protein-glutamate methylesterase activity
E6C72_26695	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E6C72_26695	COG1776	CheC inhibitor of MCP methylation
E6C72_26700	COG0840	transmembrane signaling receptor activity
E6C72_26705	COG0835	chemotaxis
E6C72_26710	COG2201	protein-glutamate methylesterase activity
E6C72_26720	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
E6C72_26730	COG2198	Histidine kinase
E6C72_26730	COG0643	Histidine kinase
E6C72_26740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E6C72_26745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E6C72_26750	COG1309	transcriptional regulator
E6C72_26760	COG0402	S-adenosylhomocysteine deaminase activity
E6C72_26765	COG1971	Probably functions as a manganese efflux pump
E6C72_26770	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
E6C72_26780	COG1131	(ABC) transporter
E6C72_26790	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
E6C72_26805	COG0489	protein tyrosine kinase activity
E6C72_26805	COG3206	protein involved in exopolysaccharide biosynthesis
E6C72_26815	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
E6C72_26820	COG1088	dTDP-glucose 4,6-dehydratase activity
E6C72_26825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E6C72_26840	COG0438	transferase activity, transferring glycosyl groups
E6C72_26845	COG1522	sequence-specific DNA binding
E6C72_26875	COG0784	Response regulator, receiver
E6C72_26885	COG3214	Protein conserved in bacteria
E6C72_26895	COG4608	Belongs to the ABC transporter superfamily
E6C72_26910	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E6C72_26930	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
E6C72_26935	COG0583	DNA-binding transcription factor activity
E6C72_26985	COG0559	Belongs to the binding-protein-dependent transport system permease family
E6C72_27050	COG2099	Precorrin-6x reductase
E6C72_27080	COG1797	cobyrinic acid a,c-diamide synthase activity
E6C72_27085	COG0778	Nitroreductase
E6C72_27090	COG1172	Belongs to the binding-protein-dependent transport system permease family
E6C72_27095	COG1129	ABC transporter
E6C72_27100	COG1879	ABC-type sugar transport system periplasmic component
E6C72_27105	COG1984	allophanate hydrolase subunit 2
E6C72_27115	COG0439	Biotin carboxylase
E6C72_27120	COG0511	ligase activity, forming carbon-carbon bonds
E6C72_27125	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
E6C72_27185	COG2189	Belongs to the N(4) N(6)-methyltransferase family
E6C72_27195	COG3012	SEC-C Motif Domain Protein
E6C72_27200	COG1278	Cold shock
E6C72_27205	COG1522	sequence-specific DNA binding
E6C72_27210	COG0586	Pfam SNARE associated Golgi protein
E6C72_27225	COG0427	acetyl-CoA hydrolase
E6C72_27245	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E6C72_27250	COG2202	Pas domain
E6C72_27250	COG2205	protein histidine kinase activity
E6C72_27265	COG1012	belongs to the aldehyde dehydrogenase family
E6C72_27270	COG2864	formate dehydrogenase
E6C72_27275	COG0437	4 iron, 4 sulfur cluster binding
E6C72_27280	COG0243	molybdopterin cofactor binding
E6C72_27280	COG3383	formate dehydrogenase (NAD+) activity
E6C72_27305	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
E6C72_27325	COG4948	Mandelate Racemase Muconate Lactonizing
E6C72_27330	COG0583	DNA-binding transcription factor activity
E6C72_27350	COG1157	protein secretion by the type III secretion system
E6C72_27355	COG0745	RESPONSE REGULATOR receiver
E6C72_27360	COG1278	Cold shock
E6C72_27385	COG0745	RESPONSE REGULATOR receiver
E6C72_27390	COG0835	chemotaxis
E6C72_27395	COG2198	Histidine kinase
E6C72_27395	COG0643	Histidine kinase
E6C72_27410	COG2205	protein histidine kinase activity
E6C72_27425	COG3920	Histidine kinase
E6C72_27435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E6C72_27450	COG0531	amino acid
E6C72_27460	COG4303	Ethanolamine ammonia lyase large subunit
E6C72_27480	COG1280	lysine exporter protein (LysE YggA)
E6C72_27495	COG2233	PERMEase
E6C72_27505	COG2723	6-phospho-beta-galactosidase activity
E6C72_27525	COG1295	ribonuclease BN
E6C72_27565	COG0793	Belongs to the peptidase S41A family
E6C72_27570	COG0736	holo-[acyl-carrier-protein] synthase activity
E6C72_27575	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
E6C72_27580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E6C72_27585	COG0671	phosphoesterase, PA-phosphatase related
E6C72_27605	COG0848	biopolymer transport protein
E6C72_27620	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_27635	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
E6C72_27650	COG1595	DNA-templated transcription, initiation
E6C72_27655	COG3806	Anti-sigma factor
E6C72_27700	COG0405	Gamma-glutamyltransferase
E6C72_27730	COG0587	DNA-directed DNA polymerase activity
E6C72_27750	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
E6C72_27770	COG1764	response to oxidative stress
E6C72_27790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E6C72_27795	COG3396	Phenylacetate-CoA oxygenase
E6C72_27800	COG3460	Phenylacetate-CoA oxygenase
E6C72_27805	COG3396	Phenylacetate-CoA oxygenase
E6C72_27810	COG2151	metal-sulfur cluster biosynthetic enzyme
E6C72_27815	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E6C72_27825	COG1024	Enoyl-CoA hydratase
E6C72_27830	COG1250	3-hydroxyacyl-CoA dehydrogenase
E6C72_27835	COG2050	protein possibly involved in aromatic compounds catabolism
E6C72_27840	COG0183	Belongs to the thiolase family
E6C72_27855	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
E6C72_27860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E6C72_27865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E6C72_27875	COG1802	Transcriptional regulator
E6C72_27880	COG1803	Methylglyoxal synthase
E6C72_27885	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
E6C72_27890	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_27895	COG1917	Cupin 2, conserved barrel domain protein
E6C72_27900	COG1802	Transcriptional regulator
E6C72_27905	COG1904	glucuronate isomerase
E6C72_27910	COG2721	sulfolactate sulfo-lyase activity
E6C72_27920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E6C72_27925	COG1309	transcriptional regulator
E6C72_27930	COG1028	Short-chain dehydrogenase reductase Sdr
E6C72_27935	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E6C72_27960	COG1309	transcriptional regulator
E6C72_27975	COG0604	alcohol dehydrogenase
E6C72_27980	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
E6C72_27990	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
E6C72_27995	COG0861	Integral membrane protein TerC family
E6C72_28000	COG0673	inositol 2-dehydrogenase activity
E6C72_28005	COG1802	Transcriptional regulator
E6C72_28010	COG1902	pentaerythritol trinitrate reductase activity
E6C72_28010	COG0446	pyridine nucleotide-disulphide oxidoreductase
E6C72_28015	COG3622	Belongs to the hyi family
E6C72_28020	COG2084	Dehydrogenase
E6C72_28030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E6C72_28030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E6C72_28035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E6C72_28055	COG2972	Histidine kinase
E6C72_28055	COG0840	transmembrane signaling receptor activity
E6C72_28060	COG0300	oxidoreductase activity
E6C72_28065	COG0116	Belongs to the methyltransferase superfamily
E6C72_28065	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
E6C72_28075	COG0840	transmembrane signaling receptor activity
E6C72_28085	COG4178	(ABC) transporter
E6C72_28120	COG1988	membrane-bound metal-dependent
E6C72_28160	COG0477	Major facilitator Superfamily
E6C72_28165	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
E6C72_28170	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
E6C72_28175	COG1845	cytochrome c oxidase, subunit III
E6C72_28180	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
E6C72_28195	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
E6C72_28200	COG0351	phosphomethylpyrimidine kinase
E6C72_28205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
E6C72_28220	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
E6C72_28230	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
E6C72_28255	COG1677	Flagellar hook-basal body complex protein FliE
E6C72_28260	COG1558	bacterial-type flagellum-dependent cell motility
E6C72_28265	COG1815	bacterial-type flagellum-dependent cell motility
E6C72_28270	COG1157	protein secretion by the type III secretion system
E6C72_28310	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
E6C72_28315	COG0745	RESPONSE REGULATOR receiver
E6C72_28350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E6C72_28355	COG2017	converts alpha-aldose to the beta-anomer
E6C72_28360	COG1172	Belongs to the binding-protein-dependent transport system permease family
E6C72_28365	COG1172	Belongs to the binding-protein-dependent transport system permease family
E6C72_28370	COG1129	ABC transporter
E6C72_28375	COG1879	ABC-type sugar transport system periplasmic component
E6C72_28410	COG1129	ABC transporter
E6C72_28415	COG4214	carbohydrate transport
E6C72_28430	COG0129	dihydroxy-acid dehydratase activity
E6C72_28440	COG0251	oxidation-reduction process
E6C72_28450	COG1966	Carbon starvation protein
E6C72_28465	COG1295	ribonuclease BN
E6C72_28470	COG3279	Response regulator of the LytR AlgR family
E6C72_28475	COG3275	phosphorelay sensor kinase activity
E6C72_28480	COG2853	Lipoprotein
E6C72_28505	COG4615	Cyclic peptide transporter
E6C72_28565	COG0318	PFAM AMP-dependent synthetase and ligase
E6C72_28575	COG0644	oxidoreductase
E6C72_28580	COG0583	DNA-binding transcription factor activity
E6C72_28590	COG1475	DNA binding
E6C72_28595	COG1192	Involved in chromosome partitioning
E6C72_28630	COG1686	Belongs to the peptidase S11 family
E6C72_28640	COG1609	Transcriptional regulator
E6C72_28645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
E6C72_28650	COG1126	abc transporter atp-binding protein
E6C72_28655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E6C72_28660	COG0765	amino acid transport
E6C72_28665	COG0765	amino acid transport
E6C72_28670	COG2814	Major facilitator Superfamily
E6C72_28675	COG2271	Major facilitator Superfamily
E6C72_28690	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
E6C72_28730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E6C72_28735	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E6C72_28750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E6C72_28800	COG1706	bacterial-type flagellum-dependent cell motility
E6C72_28810	COG1256	bacterial-type flagellum assembly
E6C72_28815	COG1749	Flagellar hook protein flgE
E6C72_28825	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
E6C72_28835	COG4786	Flagellar basal body rod
E6C72_28840	COG4786	Flagellar basal body rod
E6C72_28845	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
E6C72_28850	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
E6C72_28860	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
E6C72_28890	COG1766	The M ring may be actively involved in energy transduction
E6C72_28900	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E6C72_28905	COG1338	Plays a role in the flagellum-specific transport system
E6C72_28915	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E6C72_28925	COG0656	L-ascorbic acid biosynthetic process
E6C72_28930	COG1116	anion transmembrane transporter activity
E6C72_28940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
E6C72_28940	COG1116	anion transmembrane transporter activity
E6C72_28945	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
E6C72_28955	COG0243	molybdopterin cofactor binding
E6C72_28960	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
E6C72_28960	COG1648	precorrin-2 dehydrogenase activity
E6C72_28965	COG0791	NLP P60 protein
E6C72_28990	COG0406	alpha-ribazole phosphatase activity
E6C72_29005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E6C72_29010	COG1032	radical SAM domain protein
E6C72_29035	COG1250	3-hydroxyacyl-CoA dehydrogenase
E6C72_29040	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
E6C72_29045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E6C72_29050	COG1116	anion transmembrane transporter activity
E6C72_29055	COG0583	DNA-binding transcription factor activity
E6C72_29070	COG3663	DNA glycosylase
E6C72_29100	COG0697	spore germination
E6C72_29150	COG0516	GMP reductase activity
E6C72_29155	COG1349	DNA-binding transcription factor activity
E6C72_29175	COG3842	ATPase activity
E6C72_29180	COG3842	ATPase activity
E6C72_29205	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
E6C72_29210	COG0318	PFAM AMP-dependent synthetase and ligase
E6C72_29215	COG0789	Transcriptional regulator
E6C72_29220	COG0840	transmembrane signaling receptor activity
E6C72_29235	COG4191	Histidine kinase
E6C72_29260	COG1238	metal cluster binding
E6C72_29265	COG3852	Histidine kinase
E6C72_29270	COG0583	DNA-binding transcription factor activity
E6C72_29305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E6C72_29310	COG0463	Glycosyl transferase, family 2
E6C72_29330	COG1940	carbohydrate kinase activity
E6C72_29350	COG0411	ABC transporter
E6C72_29385	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
E6C72_29385	COG2885	chlorophyll binding
E6C72_29390	COG2197	response regulator
E6C72_29400	COG1538	Outer membrane efflux protein
E6C72_29405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E6C72_29430	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E6C72_29445	COG2814	Major facilitator Superfamily
E6C72_29480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E6C72_29485	COG0625	glutathione transferase activity
E6C72_29495	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
E6C72_29500	COG0573	inorganic phosphate transmembrane transporter activity
E6C72_29505	COG0581	inorganic phosphate transmembrane transporter activity
E6C72_29510	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
E6C72_29515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E6C72_29515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E6C72_29520	COG1280	lysine exporter protein (LysE YggA)
E6C72_29535	COG1032	radical SAM domain protein
E6C72_29540	COG5265	(ABC) transporter
E6C72_29545	COG0300	oxidoreductase activity
E6C72_29555	COG3920	Histidine kinase
E6C72_29565	COG3416	Protein conserved in bacteria
E6C72_29580	COG0784	Response regulator, receiver
E6C72_29580	COG5002	protein histidine kinase activity
E6C72_29580	COG2205	protein histidine kinase activity
E6C72_29600	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
E6C72_29615	COG3842	ATPase activity
E6C72_29625	COG1176	ABC-type spermidine putrescine transport system, permease component I
E6C72_29630	COG1802	Transcriptional regulator
E6C72_29635	COG0246	Mannitol dehydrogenase
E6C72_29640	COG1063	alcohol dehydrogenase
E6C72_29645	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
E6C72_29655	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
E6C72_29660	COG1312	Catalyzes the dehydration of D-mannonate
E6C72_29665	COG3290	protein histidine kinase activity
E6C72_29665	COG3829	transcription factor binding
E6C72_29675	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
E6C72_29690	COG3604	Transcriptional regulator
E6C72_29705	COG1737	Transcriptional regulator
E6C72_29720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E6C72_29735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E6C72_29735	COG2205	protein histidine kinase activity
E6C72_29740	COG0528	UMP kinase activity
E6C72_29745	COG0528	UMP kinase activity
E6C72_29760	COG0372	Belongs to the citrate synthase family
E6C72_29780	COG2205	protein histidine kinase activity
E6C72_29780	COG0784	Response regulator, receiver
E6C72_29780	COG5002	protein histidine kinase activity
E6C72_29785	COG2204	response regulator
E6C72_29790	COG2186	Transcriptional regulator
E6C72_29795	COG1620	l-lactate permease
E6C72_29805	COG0247	lactate metabolic process
E6C72_29810	COG1139	Iron-sulfur cluster binding protein
E6C72_29825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E6C72_29830	COG3283	Transcriptional regulator of aromatic amino acids metabolism
E6C72_29845	COG1573	uracil-dna glycosylase
E6C72_29850	COG0741	lytic transglycosylase activity
E6C72_29855	COG0521	Mo-molybdopterin cofactor biosynthetic process
E6C72_29870	COG2703	oxygen carrier activity
E6C72_29885	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
E6C72_29895	COG2202	Pas domain
E6C72_29895	COG2205	protein histidine kinase activity
E6C72_29915	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E6C72_29915	COG3218	ABC-type transport auxiliary lipoprotein component
E6C72_29920	COG1127	ABC transporter
E6C72_29925	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E6C72_29930	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
E6C72_29950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E6C72_29960	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
E6C72_29965	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
E6C72_29980	COG0640	Transcriptional regulator
E6C72_29995	COG0840	transmembrane signaling receptor activity
E6C72_30010	COG0598	Magnesium transport protein CorA
E6C72_30040	COG0305	Participates in initiation and elongation during chromosome replication
E6C72_30045	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
E6C72_30060	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E6C72_30065	COG1127	ABC transporter
E6C72_30070	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E6C72_30095	COG2723	6-phospho-beta-galactosidase activity
E6C72_30110	COG2086	electron transfer activity
E6C72_30120	COG1250	3-hydroxyacyl-CoA dehydrogenase
E6C72_30130	COG4993	Dehydrogenase
E6C72_30175	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
E6C72_30185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
E6C72_30200	COG0175	sulfate reduction
E6C72_30220	COG1216	Glycosyl transferase, family 2
E6C72_30220	COG0438	transferase activity, transferring glycosyl groups
E6C72_30225	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
E6C72_30235	COG1091	dTDP-4-dehydrorhamnose reductase activity
E6C72_30245	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E6C72_30260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E6C72_30265	COG2274	protein secretion by the type I secretion system
E6C72_30280	COG0662	Cupin 2, conserved barrel domain protein
E6C72_30280	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
E6C72_30320	COG1086	Polysaccharide biosynthesis protein
E6C72_30390	COG0189	ligase activity
E6C72_30395	COG0438	transferase activity, transferring glycosyl groups
E6C72_30420	COG2818	Glycosylase
E6C72_30435	COG1733	regulation of RNA biosynthetic process
E6C72_30455	COG0463	Glycosyl transferase, family 2
E6C72_30510	COG4638	Rieske (2fe-2S)
E6C72_30525	COG3622	Belongs to the hyi family
E6C72_30550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
E6C72_30585	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
E6C72_30640	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
E6C72_30670	COG0438	transferase activity, transferring glycosyl groups
E6C72_30680	COG1215	transferase activity, transferring glycosyl groups
E6C72_30730	COG2850	peptidyl-arginine hydroxylation
E6C72_30775	COG1132	(ABC) transporter
E6C72_30860	COG0494	nUDIX hydrolase
E6C72_30925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E6C72_30950	COG0438	transferase activity, transferring glycosyl groups
E6C72_30970	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
E6C72_30975	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
E6C72_30985	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
E6C72_31015	COG0438	transferase activity, transferring glycosyl groups
E6C72_31015	COG1216	Glycosyl transferase, family 2
E6C72_31020	COG1216	Glycosyl transferase, family 2
E6C72_31040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E6C72_31060	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
E6C72_31065	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
E6C72_31080	COG0463	Glycosyl transferase, family 2
E6C72_31115	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
E6C72_31120	COG2264	protein methyltransferase activity
E6C72_31150	COG0297	glycogen (starch) synthase activity
E6C72_31150	COG0438	transferase activity, transferring glycosyl groups
E6C72_31175	COG1192	Involved in chromosome partitioning
E6C72_31200	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E6C72_31205	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
E6C72_31220	COG1937	Protein conserved in bacteria
E6C72_31230	COG2217	Heavy metal translocating P-type atpase
E6C72_31240	COG0789	Transcriptional regulator
E6C72_31255	COG1686	Belongs to the peptidase S11 family
E6C72_31265	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
E6C72_31275	COG2321	neutral zinc metallopeptidase
E6C72_31285	COG3416	Protein conserved in bacteria
E6C72_31290	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
E6C72_31315	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
E6C72_31490	COG3916	Acyl-homoserine-lactone synthase
E6C72_31575	COG1192	Involved in chromosome partitioning