TSH58p_29805 9a2fde30ee92f46c8249f3762c0ce6c1 88 Pfam PF13617 YnbE-like lipoprotein 14 67 3.3E-24 T 14-10-2018 IPR025985 YnbE-like lipoprotein TSH58p_29805 9a2fde30ee92f46c8249f3762c0ce6c1 88 ProDom PD052969 LIPOPROTEIN PRECURSOR SIGNAL YNBE MEMBRANE OUTER POSSIBLE SIMILAR ECS2004 SO2063 26 70 4.0E-10 T 14-10-2018 TSH58p_29895 108e225dafbf4e6cba46fee97593b474 318 SMART SM00729 72 279 8.9E-11 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSH58p_29895 108e225dafbf4e6cba46fee97593b474 318 Pfam PF04055 Radical SAM superfamily 79 238 1.5E-10 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSH58p_29895 108e225dafbf4e6cba46fee97593b474 318 Hamap MF_00206 Lipoyl synthase [lipA]. 1 310 157.073 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TSH58p_29895 108e225dafbf4e6cba46fee97593b474 318 SUPERFAMILY SSF102114 38 301 3.53E-62 T 14-10-2018 TSH58p_29895 108e225dafbf4e6cba46fee97593b474 318 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 14 61 1.6E-8 T 14-10-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TSH58p_29895 108e225dafbf4e6cba46fee97593b474 318 TIGRFAM TIGR00510 lipA: lipoyl synthase 15 307 4.3E-114 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TSH58p_29895 108e225dafbf4e6cba46fee97593b474 318 Gene3D G3DSA:3.20.20.70 70 293 1.1E-17 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_29895 108e225dafbf4e6cba46fee97593b474 318 PIRSF PIRSF005963 2 317 1.9E-136 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TSH58p_07410 b7e3855800f9c03f8aceb5d7a0163893 1210 Pfam PF13116 Protein of unknown function 526 791 1.9E-22 T 14-10-2018 IPR025263 Domain of unknown function DUF3971 TSH58p_07410 b7e3855800f9c03f8aceb5d7a0163893 1210 Pfam PF13502 AsmA-like C-terminal region 964 1172 4.3E-12 T 14-10-2018 IPR032712 AsmA-like, C-terminal TSH58p_09455 62bc94e49167d8db294bf13becd74089 459 SUPERFAMILY SSF55073 301 458 1.57E-44 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_09455 62bc94e49167d8db294bf13becd74089 459 Gene3D G3DSA:1.10.490.10 6 158 3.3E-37 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 TSH58p_09455 62bc94e49167d8db294bf13becd74089 459 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 293 458 1.2E-46 T 14-10-2018 IPR000160 GGDEF domain TSH58p_09455 62bc94e49167d8db294bf13becd74089 459 Gene3D G3DSA:3.30.70.270 288 459 5.2E-53 T 14-10-2018 TSH58p_09455 62bc94e49167d8db294bf13becd74089 459 SMART SM00267 285 459 8.0E-49 T 14-10-2018 IPR000160 GGDEF domain TSH58p_09455 62bc94e49167d8db294bf13becd74089 459 SUPERFAMILY SSF46458 35 155 3.45E-17 T 14-10-2018 IPR009050 Globin-like superfamily TSH58p_09455 62bc94e49167d8db294bf13becd74089 459 Pfam PF11563 Protoglobin 20 160 1.4E-12 T 14-10-2018 TSH58p_09455 62bc94e49167d8db294bf13becd74089 459 Pfam PF00990 Diguanylate cyclase, GGDEF domain 298 455 1.3E-42 T 14-10-2018 IPR000160 GGDEF domain TSH58p_25760 5e017ee5eb158e6ba334da9d6488e7fb 359 Gene3D G3DSA:3.40.50.12780 16 312 7.0E-12 T 14-10-2018 TSH58p_25760 5e017ee5eb158e6ba334da9d6488e7fb 359 SUPERFAMILY SSF56801 58 338 1.11E-6 T 14-10-2018 TSH58p_25760 5e017ee5eb158e6ba334da9d6488e7fb 359 Pfam PF04443 Acyl-protein synthetase, LuxE 17 351 1.1E-18 T 14-10-2018 IPR007534 Acyl-protein synthetase, LuxE GO:0008218|GO:0047474 MetaCyc: PWY-7723 TSH58p_07940 485a72eb0cd96635e27a151dd80af9c4 690 SMART SM00387 542 655 1.2E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_07940 485a72eb0cd96635e27a151dd80af9c4 690 SUPERFAMILY SSF158472 349 399 5.75E-6 T 14-10-2018 TSH58p_07940 485a72eb0cd96635e27a151dd80af9c4 690 SMART SM00388 427 495 1.1E-6 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_07940 485a72eb0cd96635e27a151dd80af9c4 690 SMART SM01358 71 320 2.9E-19 T 14-10-2018 IPR032255 Helical bimodular sensor domain TSH58p_07940 485a72eb0cd96635e27a151dd80af9c4 690 SUPERFAMILY SSF55874 485 660 9.43E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_07940 485a72eb0cd96635e27a151dd80af9c4 690 Gene3D G3DSA:3.30.565.10 497 656 8.5E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_07940 485a72eb0cd96635e27a151dd80af9c4 690 SUPERFAMILY SSF47384 414 497 8.63E-12 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_07940 485a72eb0cd96635e27a151dd80af9c4 690 PRINTS PR00344 Bacterial sensor protein C-terminal signature 639 652 5.9E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_07940 485a72eb0cd96635e27a151dd80af9c4 690 PRINTS PR00344 Bacterial sensor protein C-terminal signature 615 633 5.9E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_07940 485a72eb0cd96635e27a151dd80af9c4 690 PRINTS PR00344 Bacterial sensor protein C-terminal signature 582 596 5.9E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_07940 485a72eb0cd96635e27a151dd80af9c4 690 PRINTS PR00344 Bacterial sensor protein C-terminal signature 600 610 5.9E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_07940 485a72eb0cd96635e27a151dd80af9c4 690 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 545 653 5.6E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_07940 485a72eb0cd96635e27a151dd80af9c4 690 Gene3D G3DSA:1.20.1480.50 313 408 2.3E-10 T 14-10-2018 TSH58p_07940 485a72eb0cd96635e27a151dd80af9c4 690 Pfam PF00672 HAMP domain 349 396 1.8E-6 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_07940 485a72eb0cd96635e27a151dd80af9c4 690 SMART SM00304 349 402 1.2E-5 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_07940 485a72eb0cd96635e27a151dd80af9c4 690 Gene3D G3DSA:1.10.287.130 413 496 2.0E-12 T 14-10-2018 TSH58p_14430 ede0969d54894e792dd45bdb61ced720 711 PRINTS PR00344 Bacterial sensor protein C-terminal signature 518 528 4.1E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_14430 ede0969d54894e792dd45bdb61ced720 711 PRINTS PR00344 Bacterial sensor protein C-terminal signature 500 514 4.1E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_14430 ede0969d54894e792dd45bdb61ced720 711 PRINTS PR00344 Bacterial sensor protein C-terminal signature 555 568 4.1E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_14430 ede0969d54894e792dd45bdb61ced720 711 PRINTS PR00344 Bacterial sensor protein C-terminal signature 531 549 4.1E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_14430 ede0969d54894e792dd45bdb61ced720 711 Gene3D G3DSA:1.10.287.130 346 416 3.2E-18 T 14-10-2018 TSH58p_14430 ede0969d54894e792dd45bdb61ced720 711 SMART SM00388 354 418 1.1E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_14430 ede0969d54894e792dd45bdb61ced720 711 Gene3D G3DSA:3.40.50.2300 590 710 3.6E-27 T 14-10-2018 TSH58p_14430 ede0969d54894e792dd45bdb61ced720 711 Pfam PF00072 Response regulator receiver domain 594 701 3.1E-17 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_14430 ede0969d54894e792dd45bdb61ced720 711 SUPERFAMILY SSF47384 344 416 1.31E-9 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_14430 ede0969d54894e792dd45bdb61ced720 711 SUPERFAMILY SSF55874 408 569 1.03E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_14430 ede0969d54894e792dd45bdb61ced720 711 Gene3D G3DSA:3.30.450.20 195 284 1.9E-18 T 14-10-2018 TSH58p_14430 ede0969d54894e792dd45bdb61ced720 711 SUPERFAMILY SSF52172 590 706 6.12E-27 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_14430 ede0969d54894e792dd45bdb61ced720 711 Gene3D G3DSA:3.30.565.10 420 575 1.1E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_14430 ede0969d54894e792dd45bdb61ced720 711 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 460 569 4.6E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_14430 ede0969d54894e792dd45bdb61ced720 711 Pfam PF00512 His Kinase A (phospho-acceptor) domain 354 417 1.0E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_14430 ede0969d54894e792dd45bdb61ced720 711 SMART SM00387 459 571 3.5E-31 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_14430 ede0969d54894e792dd45bdb61ced720 711 Gene3D G3DSA:3.30.450.20 39 193 2.7E-27 T 14-10-2018 TSH58p_14430 ede0969d54894e792dd45bdb61ced720 711 SMART SM00448 591 701 1.8E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_12595 7a76b7e5c4f9f358c015bcb1525e61f8 517 PRINTS PR00419 Adrenodoxin reductase family signature 27 40 2.5E-7 T 14-10-2018 TSH58p_12595 7a76b7e5c4f9f358c015bcb1525e61f8 517 PRINTS PR00419 Adrenodoxin reductase family signature 4 26 2.5E-7 T 14-10-2018 TSH58p_12595 7a76b7e5c4f9f358c015bcb1525e61f8 517 Pfam PF01593 Flavin containing amine oxidoreductase 13 471 4.6E-28 T 14-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 TSH58p_12595 7a76b7e5c4f9f358c015bcb1525e61f8 517 Gene3D G3DSA:3.50.50.60 2 114 1.0E-22 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_12595 7a76b7e5c4f9f358c015bcb1525e61f8 517 Gene3D G3DSA:3.50.50.60 201 324 3.6E-17 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_12595 7a76b7e5c4f9f358c015bcb1525e61f8 517 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 5 492 4.5E-161 T 14-10-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 TSH58p_12595 7a76b7e5c4f9f358c015bcb1525e61f8 517 ProSitePatterns PS00982 Bacterial-type phytoene dehydrogenase signature. 459 479 - T 14-10-2018 IPR008150 Phytoene dehydrogenase, bacterial-type, conserved site TSH58p_12595 7a76b7e5c4f9f358c015bcb1525e61f8 517 SUPERFAMILY SSF51905 2 487 1.42E-64 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_04065 137768f38ea5124afc7d6950ee0049b5 420 Gene3D G3DSA:3.40.47.10 1 261 1.2E-87 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_04065 137768f38ea5124afc7d6950ee0049b5 420 SUPERFAMILY SSF53901 221 419 5.6E-73 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_04065 137768f38ea5124afc7d6950ee0049b5 420 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 2 417 1.2E-191 T 14-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 TSH58p_04065 137768f38ea5124afc7d6950ee0049b5 420 Gene3D G3DSA:3.40.47.10 267 420 3.5E-53 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_04065 137768f38ea5124afc7d6950ee0049b5 420 SUPERFAMILY SSF53901 1 260 6.29E-77 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_04065 137768f38ea5124afc7d6950ee0049b5 420 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 253 7.1E-63 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TSH58p_04065 137768f38ea5124afc7d6950ee0049b5 420 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 160 176 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site TSH58p_04065 137768f38ea5124afc7d6950ee0049b5 420 SMART SM00825 Beta-ketoacyl synthase 4 420 2.5E-17 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TSH58p_04065 137768f38ea5124afc7d6950ee0049b5 420 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 261 375 9.2E-40 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TSH58p_04065 137768f38ea5124afc7d6950ee0049b5 420 PIRSF PIRSF000447 1 420 2.1E-189 T 14-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 Gene3D G3DSA:2.150.10.10 266 337 9.7E-13 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 SUPERFAMILY SSF51120 96 180 3.79E-19 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 278 296 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 Gene3D G3DSA:2.150.10.10 216 265 9.0E-12 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 453 471 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 79 96 0.027 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 346 354 11.0 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 106 123 5.6E-4 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 264 280 0.11 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 218 235 0.012 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 246 262 0.0016 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 282 298 8.0E-4 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 466 481 2.2 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 53 69 2.9 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 366 383 0.033 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 134 150 7.0E-4 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 198 212 34.0 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 151 163 2.8 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 448 464 0.14 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 SUPERFAMILY SSF51120 411 561 9.42E-19 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 130 148 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 Gene3D G3DSA:2.150.10.10 132 207 1.0E-8 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 Gene3D G3DSA:2.150.10.10 91 131 1.8E-10 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 SUPERFAMILY SSF51120 260 331 1.16E-15 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 260 278 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 SUPERFAMILY SSF51120 152 268 2.75E-19 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 SUPERFAMILY SSF51120 28 114 1.31E-16 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 112 130 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 Gene3D G3DSA:2.150.10.10 341 396 1.2E-8 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 269 287 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 SUPERFAMILY SSF51120 315 399 4.84E-11 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 103 121 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 PRINTS PR00313 NodO calcium binding signature 125 133 1.5E-9 T 14-10-2018 TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 PRINTS PR00313 NodO calcium binding signature 152 160 1.5E-9 T 14-10-2018 TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 PRINTS PR00313 NodO calcium binding signature 170 179 1.5E-9 T 14-10-2018 TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 PRINTS PR00313 NodO calcium binding signature 113 124 1.5E-9 T 14-10-2018 TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 Gene3D G3DSA:2.150.10.10 28 90 6.0E-9 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_27690 9fa8661960d58e4e83ff054e238facee 579 Gene3D G3DSA:2.150.10.10 420 577 4.2E-28 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_11420 c91aa60c2677c27510c722ae97ef5f6a 707 Pfam PF00575 S1 RNA binding domain 617 688 7.6E-16 T 14-10-2018 IPR003029 S1 domain GO:0003676 TSH58p_11420 c91aa60c2677c27510c722ae97ef5f6a 707 SMART SM00316 618 688 5.7E-19 T 14-10-2018 IPR022967 RNA-binding domain, S1 TSH58p_11420 c91aa60c2677c27510c722ae97ef5f6a 707 SUPERFAMILY SSF55666 145 234 4.07E-29 T 14-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSH58p_11420 c91aa60c2677c27510c722ae97ef5f6a 707 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 242 318 9.7E-13 T 14-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TSH58p_11420 c91aa60c2677c27510c722ae97ef5f6a 707 Gene3D G3DSA:3.30.230.70 1 230 3.3E-87 T 14-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSH58p_11420 c91aa60c2677c27510c722ae97ef5f6a 707 SUPERFAMILY SSF54211 2 144 1.11E-53 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSH58p_11420 c91aa60c2677c27510c722ae97ef5f6a 707 Pfam PF00013 KH domain 554 611 1.1E-10 T 14-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 TSH58p_11420 c91aa60c2677c27510c722ae97ef5f6a 707 Pfam PF01138 3' exoribonuclease family, domain 1 14 144 5.2E-25 T 14-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSH58p_11420 c91aa60c2677c27510c722ae97ef5f6a 707 Pfam PF01138 3' exoribonuclease family, domain 1 322 454 1.1E-20 T 14-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSH58p_11420 c91aa60c2677c27510c722ae97ef5f6a 707 Gene3D G3DSA:3.30.1370.10 548 619 1.2E-18 T 14-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TSH58p_11420 c91aa60c2677c27510c722ae97ef5f6a 707 PIRSF PIRSF005499 1 707 2.4E-292 T 14-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TSH58p_11420 c91aa60c2677c27510c722ae97ef5f6a 707 SUPERFAMILY SSF54791 552 638 5.31E-22 T 14-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TSH58p_11420 c91aa60c2677c27510c722ae97ef5f6a 707 SMART SM00322 550 615 7.8E-12 T 14-10-2018 IPR004087 K Homology domain GO:0003676 TSH58p_11420 c91aa60c2677c27510c722ae97ef5f6a 707 SUPERFAMILY SSF54211 291 486 6.58E-47 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSH58p_11420 c91aa60c2677c27510c722ae97ef5f6a 707 Gene3D G3DSA:2.40.50.140 620 692 2.4E-28 T 14-10-2018 TSH58p_11420 c91aa60c2677c27510c722ae97ef5f6a 707 SUPERFAMILY SSF50249 618 701 6.71E-20 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_11420 c91aa60c2677c27510c722ae97ef5f6a 707 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 10 690 0.0 T 14-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TSH58p_11420 c91aa60c2677c27510c722ae97ef5f6a 707 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 3 691 30.658 T 14-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TSH58p_11420 c91aa60c2677c27510c722ae97ef5f6a 707 Gene3D G3DSA:3.30.230.70 237 547 2.1E-113 T 14-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSH58p_11420 c91aa60c2677c27510c722ae97ef5f6a 707 SUPERFAMILY SSF55666 448 544 3.75E-26 T 14-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSH58p_11420 c91aa60c2677c27510c722ae97ef5f6a 707 Pfam PF03725 3' exoribonuclease family, domain 2 147 211 3.2E-12 T 14-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSH58p_11420 c91aa60c2677c27510c722ae97ef5f6a 707 Pfam PF03725 3' exoribonuclease family, domain 2 458 527 2.0E-5 T 14-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSH58p_07115 6b2fe30da8734f84d05f3ef40b2dd600 251 Gene3D G3DSA:2.150.10.10 41 116 1.1E-14 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_07115 6b2fe30da8734f84d05f3ef40b2dd600 251 Gene3D G3DSA:2.150.10.10 117 239 6.7E-20 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_07115 6b2fe30da8734f84d05f3ef40b2dd600 251 SUPERFAMILY SSF51120 42 127 1.24E-19 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_07115 6b2fe30da8734f84d05f3ef40b2dd600 251 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 101 119 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_07115 6b2fe30da8734f84d05f3ef40b2dd600 251 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 149 166 0.0059 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_07115 6b2fe30da8734f84d05f3ef40b2dd600 251 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 89 103 0.0032 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_07115 6b2fe30da8734f84d05f3ef40b2dd600 251 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 122 139 0.0052 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_07115 6b2fe30da8734f84d05f3ef40b2dd600 251 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 105 121 0.0021 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_07115 6b2fe30da8734f84d05f3ef40b2dd600 251 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 69 85 0.0033 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_07115 6b2fe30da8734f84d05f3ef40b2dd600 251 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 119 137 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_07115 6b2fe30da8734f84d05f3ef40b2dd600 251 PRINTS PR00313 NodO calcium binding signature 159 168 3.9E-12 T 14-10-2018 TSH58p_07115 6b2fe30da8734f84d05f3ef40b2dd600 251 PRINTS PR00313 NodO calcium binding signature 150 158 3.9E-12 T 14-10-2018 TSH58p_07115 6b2fe30da8734f84d05f3ef40b2dd600 251 PRINTS PR00313 NodO calcium binding signature 111 122 3.9E-12 T 14-10-2018 TSH58p_07115 6b2fe30da8734f84d05f3ef40b2dd600 251 PRINTS PR00313 NodO calcium binding signature 132 140 3.9E-12 T 14-10-2018 TSH58p_07115 6b2fe30da8734f84d05f3ef40b2dd600 251 SUPERFAMILY SSF51120 112 239 4.97E-21 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_10380 4863eb84d119cd9d8ec059b85e63fbf3 244 SMART SM00382 40 232 4.6E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_10380 4863eb84d119cd9d8ec059b85e63fbf3 244 SUPERFAMILY SSF52540 12 232 1.01E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_10380 4863eb84d119cd9d8ec059b85e63fbf3 244 Pfam PF00005 ABC transporter 31 177 4.0E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_10380 4863eb84d119cd9d8ec059b85e63fbf3 244 Gene3D G3DSA:3.40.50.300 9 240 6.1E-73 T 14-10-2018 TSH58p_10380 4863eb84d119cd9d8ec059b85e63fbf3 244 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_18790 ac0568fba1e074193d0f4fcbcf40ce01 379 Gene3D G3DSA:1.10.760.10 274 366 3.4E-17 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_18790 ac0568fba1e074193d0f4fcbcf40ce01 379 SUPERFAMILY SSF46626 278 365 2.11E-12 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_18790 ac0568fba1e074193d0f4fcbcf40ce01 379 Gene3D G3DSA:1.10.760.10 64 158 5.7E-17 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_18790 ac0568fba1e074193d0f4fcbcf40ce01 379 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 70 151 5.5E-13 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_18790 ac0568fba1e074193d0f4fcbcf40ce01 379 Gene3D G3DSA:1.10.760.10 188 268 1.3E-17 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_18790 ac0568fba1e074193d0f4fcbcf40ce01 379 SUPERFAMILY SSF46626 55 164 5.38E-19 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_18790 ac0568fba1e074193d0f4fcbcf40ce01 379 SUPERFAMILY SSF46626 194 271 2.73E-14 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_16890 63290ea0ac6f4c67e966d1ebcbab5676 97 ProSitePatterns PS00202 Rubredoxin signature. 76 86 - T 14-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 TSH58p_16890 63290ea0ac6f4c67e966d1ebcbab5676 97 SUPERFAMILY SSF57802 51 95 3.73E-14 T 14-10-2018 TSH58p_16890 63290ea0ac6f4c67e966d1ebcbab5676 97 Pfam PF00301 Rubredoxin 51 92 6.5E-15 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 TSH58p_16890 63290ea0ac6f4c67e966d1ebcbab5676 97 Gene3D G3DSA:2.20.28.10 42 96 7.4E-21 T 14-10-2018 TSH58p_21680 35e8606f63a52e91ee9f8d7103c7ac28 368 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 46 325 4.3E-59 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 TSH58p_21680 35e8606f63a52e91ee9f8d7103c7ac28 368 PIRSF PIRSF039026 1 363 4.9E-124 T 14-10-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like TSH58p_21680 35e8606f63a52e91ee9f8d7103c7ac28 368 Gene3D G3DSA:3.40.190.10 158 329 5.5E-125 T 14-10-2018 TSH58p_21680 35e8606f63a52e91ee9f8d7103c7ac28 368 Gene3D G3DSA:3.40.190.170 39 342 5.5E-125 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily TSH58p_28940 cce0a613a9cef44270d912c1daa49dc7 95 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 95 5.3E-27 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 TSH58p_28940 cce0a613a9cef44270d912c1daa49dc7 95 SUPERFAMILY SSF141000 2 93 6.54E-29 T 14-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 TSH58p_28940 cce0a613a9cef44270d912c1daa49dc7 95 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 95 23.798 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 TSH58p_28940 cce0a613a9cef44270d912c1daa49dc7 95 Gene3D G3DSA:1.10.20.60 1 93 2.3E-26 T 14-10-2018 TSH58p_28940 cce0a613a9cef44270d912c1daa49dc7 95 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 90 7.2E-20 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 TSH58p_14490 999b541559b8239af08a2029058ec86c 695 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 3 693 6.7E-197 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TSH58p_14490 999b541559b8239af08a2029058ec86c 695 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 4 551 9.2E-213 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TSH58p_14490 999b541559b8239af08a2029058ec86c 695 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 1 693 24.676 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TSH58p_14490 999b541559b8239af08a2029058ec86c 695 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 243 258 1.5E-32 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TSH58p_14490 999b541559b8239af08a2029058ec86c 695 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 48 60 1.5E-32 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TSH58p_14490 999b541559b8239af08a2029058ec86c 695 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 5 18 1.5E-32 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TSH58p_14490 999b541559b8239af08a2029058ec86c 695 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 316 332 1.5E-32 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TSH58p_14490 999b541559b8239af08a2029058ec86c 695 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 392 411 1.5E-32 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TSH58p_14490 999b541559b8239af08a2029058ec86c 695 Pfam PF05746 DALR anticodon binding domain 581 686 1.7E-8 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 TSH58p_14490 999b541559b8239af08a2029058ec86c 695 SUPERFAMILY SSF109604 339 488 2.88E-20 T 14-10-2018 TSH58p_09450 00167ce862e1d233282a778576450991 748 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 620 731 2.6E-27 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_09450 00167ce862e1d233282a778576450991 748 Pfam PF02743 Cache domain 78 248 2.5E-12 T 14-10-2018 IPR033479 Double Cache domain 1 TSH58p_09450 00167ce862e1d233282a778576450991 748 SMART SM00091 356 422 1.1E-10 T 14-10-2018 IPR000014 PAS domain TSH58p_09450 00167ce862e1d233282a778576450991 748 Gene3D G3DSA:3.30.450.20 352 483 3.0E-32 T 14-10-2018 TSH58p_09450 00167ce862e1d233282a778576450991 748 SUPERFAMILY SSF47384 492 574 5.3E-22 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_09450 00167ce862e1d233282a778576450991 748 SUPERFAMILY SSF55874 563 730 2.49E-48 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_09450 00167ce862e1d233282a778576450991 748 SMART SM00387 619 732 1.7E-41 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_09450 00167ce862e1d233282a778576450991 748 SUPERFAMILY SSF55785 367 492 1.65E-24 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_09450 00167ce862e1d233282a778576450991 748 Gene3D G3DSA:1.10.287.130 484 571 1.6E-28 T 14-10-2018 TSH58p_09450 00167ce862e1d233282a778576450991 748 Gene3D G3DSA:3.30.450.20 218 303 1.8E-8 T 14-10-2018 TSH58p_09450 00167ce862e1d233282a778576450991 748 SMART SM00388 505 573 2.1E-24 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_09450 00167ce862e1d233282a778576450991 748 Pfam PF00989 PAS fold 357 456 3.1E-13 T 14-10-2018 IPR013767 PAS fold GO:0006355 TSH58p_09450 00167ce862e1d233282a778576450991 748 Gene3D G3DSA:3.30.450.20 55 211 5.7E-33 T 14-10-2018 TSH58p_09450 00167ce862e1d233282a778576450991 748 Pfam PF00512 His Kinase A (phospho-acceptor) domain 505 573 1.3E-20 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_09450 00167ce862e1d233282a778576450991 748 PRINTS PR00344 Bacterial sensor protein C-terminal signature 675 685 1.6E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_09450 00167ce862e1d233282a778576450991 748 PRINTS PR00344 Bacterial sensor protein C-terminal signature 692 710 1.6E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_09450 00167ce862e1d233282a778576450991 748 PRINTS PR00344 Bacterial sensor protein C-terminal signature 657 671 1.6E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_09450 00167ce862e1d233282a778576450991 748 PRINTS PR00344 Bacterial sensor protein C-terminal signature 716 729 1.6E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_09450 00167ce862e1d233282a778576450991 748 Gene3D G3DSA:3.30.565.10 572 734 1.5E-48 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_09450 00167ce862e1d233282a778576450991 748 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 356 492 5.5E-23 T 14-10-2018 IPR000014 PAS domain TSH58p_09495 76f879eb3607a9ad96ac3cd9cc59cbf1 371 SMART SM01329 6 362 1.9E-184 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 TSH58p_09495 76f879eb3607a9ad96ac3cd9cc59cbf1 371 SUPERFAMILY SSF53659 2 368 6.53E-114 T 14-10-2018 TSH58p_09495 76f879eb3607a9ad96ac3cd9cc59cbf1 371 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 5 366 49.739 T 14-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 TSH58p_09495 76f879eb3607a9ad96ac3cd9cc59cbf1 371 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 7 361 1.1E-144 T 14-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 TSH58p_09495 76f879eb3607a9ad96ac3cd9cc59cbf1 371 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 7 362 8.7E-131 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 TSH58p_09495 76f879eb3607a9ad96ac3cd9cc59cbf1 371 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 248 267 - T 14-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 TSH58p_09495 76f879eb3607a9ad96ac3cd9cc59cbf1 371 Gene3D G3DSA:3.40.718.10 4 371 4.2E-134 T 14-10-2018 TSH58p_06950 4638f313d90ec0ff72ea2feecd9f6107 466 PRINTS PR00145 Argininosuccinate lyase family signature 320 336 8.9E-8 T 14-10-2018 TSH58p_06950 4638f313d90ec0ff72ea2feecd9f6107 466 PRINTS PR00145 Argininosuccinate lyase family signature 178 198 8.9E-8 T 14-10-2018 TSH58p_06950 4638f313d90ec0ff72ea2feecd9f6107 466 PRINTS PR00145 Argininosuccinate lyase family signature 136 158 8.9E-8 T 14-10-2018 TSH58p_06950 4638f313d90ec0ff72ea2feecd9f6107 466 Pfam PF00206 Lyase 15 345 3.7E-119 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal TSH58p_06950 4638f313d90ec0ff72ea2feecd9f6107 466 Gene3D G3DSA:1.20.200.10 142 409 3.1E-123 T 14-10-2018 TSH58p_06950 4638f313d90ec0ff72ea2feecd9f6107 466 Pfam PF10415 Fumarase C C-terminus 411 463 1.4E-27 T 14-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSH58p_06950 4638f313d90ec0ff72ea2feecd9f6107 466 Gene3D G3DSA:1.10.275.10 8 141 5.4E-58 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal TSH58p_06950 4638f313d90ec0ff72ea2feecd9f6107 466 PRINTS PR00149 Fumarate lyase superfamily signature 320 336 8.3E-37 T 14-10-2018 IPR000362 Fumarate lyase family TSH58p_06950 4638f313d90ec0ff72ea2feecd9f6107 466 PRINTS PR00149 Fumarate lyase superfamily signature 137 155 8.3E-37 T 14-10-2018 IPR000362 Fumarate lyase family TSH58p_06950 4638f313d90ec0ff72ea2feecd9f6107 466 PRINTS PR00149 Fumarate lyase superfamily signature 274 301 8.3E-37 T 14-10-2018 IPR000362 Fumarate lyase family TSH58p_06950 4638f313d90ec0ff72ea2feecd9f6107 466 PRINTS PR00149 Fumarate lyase superfamily signature 183 201 8.3E-37 T 14-10-2018 IPR000362 Fumarate lyase family TSH58p_06950 4638f313d90ec0ff72ea2feecd9f6107 466 SUPERFAMILY SSF48557 7 466 8.48E-165 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 TSH58p_06950 4638f313d90ec0ff72ea2feecd9f6107 466 Gene3D G3DSA:1.10.40.30 411 466 1.5E-30 T 14-10-2018 TSH58p_06950 4638f313d90ec0ff72ea2feecd9f6107 466 Hamap MF_00743 Fumarate hydratase class II [fumC]. 7 465 92.908 T 14-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSH58p_06950 4638f313d90ec0ff72ea2feecd9f6107 466 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 7 464 4.0E-237 T 14-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSH58p_06950 4638f313d90ec0ff72ea2feecd9f6107 466 ProSitePatterns PS00163 Fumarate lyases signature. 320 329 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 TSH58p_27345 4910b4d3782eac5f52482684f6225167 324 Gene3D G3DSA:1.10.10.10 21 109 9.7E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_27345 4910b4d3782eac5f52482684f6225167 324 SUPERFAMILY SSF46785 21 128 1.13E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_27345 4910b4d3782eac5f52482684f6225167 324 Gene3D G3DSA:3.40.190.10 182 283 8.6E-52 T 14-10-2018 TSH58p_27345 4910b4d3782eac5f52482684f6225167 324 SUPERFAMILY SSF53850 110 312 5.43E-37 T 14-10-2018 TSH58p_27345 4910b4d3782eac5f52482684f6225167 324 Pfam PF03466 LysR substrate binding domain 108 311 6.7E-35 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_27345 4910b4d3782eac5f52482684f6225167 324 Gene3D G3DSA:3.40.190.10 111 310 8.6E-52 T 14-10-2018 TSH58p_27345 4910b4d3782eac5f52482684f6225167 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 49 8.5E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_27345 4910b4d3782eac5f52482684f6225167 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 49 59 8.5E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_27345 4910b4d3782eac5f52482684f6225167 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 59 70 8.5E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_27345 4910b4d3782eac5f52482684f6225167 324 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 23 82 5.6E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_30145 41d4cdafa576dd68b6f80914a7755d37 309 Pfam PF16280 Domain of unknown function (DUF4928) 20 304 5.2E-47 T 14-10-2018 IPR032564 Protein of unknown function DUF4928 TSH58p_29985 41d4cdafa576dd68b6f80914a7755d37 309 Pfam PF16280 Domain of unknown function (DUF4928) 20 304 5.2E-47 T 14-10-2018 IPR032564 Protein of unknown function DUF4928 TSH58p_24125 084ac41f7f9f9be884b220e3dbfcb58e 825 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 701 809 8.5E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_24125 084ac41f7f9f9be884b220e3dbfcb58e 825 Gene3D G3DSA:1.10.287.130 549 650 4.5E-20 T 14-10-2018 TSH58p_24125 084ac41f7f9f9be884b220e3dbfcb58e 825 Pfam PF13426 PAS domain 435 534 1.3E-7 T 14-10-2018 IPR000014 PAS domain TSH58p_24125 084ac41f7f9f9be884b220e3dbfcb58e 825 SUPERFAMILY SSF55874 652 812 1.44E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_24125 084ac41f7f9f9be884b220e3dbfcb58e 825 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 420 543 5.2E-17 T 14-10-2018 IPR000014 PAS domain TSH58p_24125 084ac41f7f9f9be884b220e3dbfcb58e 825 SMART SM00091 423 489 8.0E-7 T 14-10-2018 IPR000014 PAS domain TSH58p_24125 084ac41f7f9f9be884b220e3dbfcb58e 825 Gene3D G3DSA:3.30.565.10 658 815 1.4E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_24125 084ac41f7f9f9be884b220e3dbfcb58e 825 Gene3D G3DSA:3.30.450.20 410 534 8.3E-19 T 14-10-2018 TSH58p_24125 084ac41f7f9f9be884b220e3dbfcb58e 825 PRINTS PR00344 Bacterial sensor protein C-terminal signature 771 789 4.9E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_24125 084ac41f7f9f9be884b220e3dbfcb58e 825 PRINTS PR00344 Bacterial sensor protein C-terminal signature 740 754 4.9E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_24125 084ac41f7f9f9be884b220e3dbfcb58e 825 PRINTS PR00344 Bacterial sensor protein C-terminal signature 758 768 4.9E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_24125 084ac41f7f9f9be884b220e3dbfcb58e 825 PRINTS PR00344 Bacterial sensor protein C-terminal signature 796 809 4.9E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_24125 084ac41f7f9f9be884b220e3dbfcb58e 825 SMART SM00387 699 812 5.2E-25 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_24125 084ac41f7f9f9be884b220e3dbfcb58e 825 SUPERFAMILY SSF55785 408 534 2.62E-19 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_01280 7f620d4b68eb8d4457501d845e317df5 513 SMART SM00387 400 510 5.5E-30 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_01280 7f620d4b68eb8d4457501d845e317df5 513 Pfam PF00512 His Kinase A (phospho-acceptor) domain 289 355 2.9E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_01280 7f620d4b68eb8d4457501d845e317df5 513 SUPERFAMILY SSF55874 351 508 1.83E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_01280 7f620d4b68eb8d4457501d845e317df5 513 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 131 189 3.4E-9 T 14-10-2018 IPR000014 PAS domain TSH58p_01280 7f620d4b68eb8d4457501d845e317df5 513 Pfam PF08448 PAS fold 141 268 5.4E-9 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_01280 7f620d4b68eb8d4457501d845e317df5 513 SUPERFAMILY SSF47384 285 354 1.55E-8 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_01280 7f620d4b68eb8d4457501d845e317df5 513 Gene3D G3DSA:3.30.450.20 126 267 8.2E-22 T 14-10-2018 TSH58p_01280 7f620d4b68eb8d4457501d845e317df5 513 SUPERFAMILY SSF55785 126 264 2.9E-14 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_01280 7f620d4b68eb8d4457501d845e317df5 513 SMART SM00388 288 358 2.7E-7 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_01280 7f620d4b68eb8d4457501d845e317df5 513 Pfam PF00072 Response regulator receiver domain 6 116 8.8E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_01280 7f620d4b68eb8d4457501d845e317df5 513 SUPERFAMILY SSF52172 5 132 2.28E-34 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_01280 7f620d4b68eb8d4457501d845e317df5 513 SMART SM00091 134 202 3.3E-8 T 14-10-2018 IPR000014 PAS domain TSH58p_01280 7f620d4b68eb8d4457501d845e317df5 513 SMART SM00448 4 116 5.3E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_01280 7f620d4b68eb8d4457501d845e317df5 513 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 400 508 2.0E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_01280 7f620d4b68eb8d4457501d845e317df5 513 Gene3D G3DSA:1.10.287.130 268 352 5.2E-17 T 14-10-2018 TSH58p_01280 7f620d4b68eb8d4457501d845e317df5 513 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 455 4.8E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_01280 7f620d4b68eb8d4457501d845e317df5 513 PRINTS PR00344 Bacterial sensor protein C-terminal signature 470 488 4.8E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_01280 7f620d4b68eb8d4457501d845e317df5 513 PRINTS PR00344 Bacterial sensor protein C-terminal signature 494 507 4.8E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_01280 7f620d4b68eb8d4457501d845e317df5 513 Gene3D G3DSA:3.30.565.10 359 510 1.4E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_01280 7f620d4b68eb8d4457501d845e317df5 513 Gene3D G3DSA:3.40.50.2300 2 125 1.0E-33 T 14-10-2018 TSH58p_00365 fbcbd7663e076740cdf5f8d70a9f8d39 339 SUPERFAMILY SSF51735 1 329 1.41E-94 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_00365 fbcbd7663e076740cdf5f8d70a9f8d39 339 Gene3D G3DSA:3.40.50.720 7 254 6.8E-120 T 14-10-2018 TSH58p_00365 fbcbd7663e076740cdf5f8d70a9f8d39 339 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 254 5.5E-54 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TSH58p_00365 fbcbd7663e076740cdf5f8d70a9f8d39 339 Gene3D G3DSA:3.90.25.10 177 308 6.8E-120 T 14-10-2018 TSH58p_00365 fbcbd7663e076740cdf5f8d70a9f8d39 339 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 7 328 3.6E-123 T 14-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 TSH58p_18050 9eb7fa2f380b953b58bf5aa5c9a39fe8 467 SUPERFAMILY SSF53738 6 132 2.63E-41 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_18050 9eb7fa2f380b953b58bf5aa5c9a39fe8 467 SUPERFAMILY SSF53738 257 365 1.1E-33 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_18050 9eb7fa2f380b953b58bf5aa5c9a39fe8 467 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 258 366 2.5E-20 T 14-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_18050 9eb7fa2f380b953b58bf5aa5c9a39fe8 467 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 156 253 1.0E-20 T 14-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_18050 9eb7fa2f380b953b58bf5aa5c9a39fe8 467 Gene3D G3DSA:3.40.120.10 251 367 2.4E-37 T 14-10-2018 TSH58p_18050 9eb7fa2f380b953b58bf5aa5c9a39fe8 467 SUPERFAMILY SSF55957 366 452 6.28E-22 T 14-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_18050 9eb7fa2f380b953b58bf5aa5c9a39fe8 467 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 13 125 9.7E-37 T 14-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_18050 9eb7fa2f380b953b58bf5aa5c9a39fe8 467 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 99 113 7.0E-22 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_18050 9eb7fa2f380b953b58bf5aa5c9a39fe8 467 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 233 248 7.0E-22 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_18050 9eb7fa2f380b953b58bf5aa5c9a39fe8 467 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 170 189 7.0E-22 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_18050 9eb7fa2f380b953b58bf5aa5c9a39fe8 467 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 204 217 7.0E-22 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_18050 9eb7fa2f380b953b58bf5aa5c9a39fe8 467 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 373 451 1.4E-12 T 14-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_18050 9eb7fa2f380b953b58bf5aa5c9a39fe8 467 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 100 109 - T 14-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_18050 9eb7fa2f380b953b58bf5aa5c9a39fe8 467 Gene3D G3DSA:3.40.120.10 172 249 2.0E-26 T 14-10-2018 TSH58p_18050 9eb7fa2f380b953b58bf5aa5c9a39fe8 467 Gene3D G3DSA:3.40.120.10 2 152 6.4E-50 T 14-10-2018 TSH58p_18050 9eb7fa2f380b953b58bf5aa5c9a39fe8 467 SUPERFAMILY SSF53738 155 254 4.32E-27 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_18050 9eb7fa2f380b953b58bf5aa5c9a39fe8 467 Gene3D G3DSA:3.30.310.50 369 457 3.7E-23 T 14-10-2018 TSH58p_11840 2872f50daafdc15f44fad032acff4602 142 Pfam PF00571 CBS domain 72 124 3.2E-11 T 14-10-2018 IPR000644 CBS domain TSH58p_11840 2872f50daafdc15f44fad032acff4602 142 Pfam PF00571 CBS domain 13 56 1.6E-9 T 14-10-2018 IPR000644 CBS domain TSH58p_11840 2872f50daafdc15f44fad032acff4602 142 Gene3D G3DSA:3.10.580.10 1 137 2.0E-37 T 14-10-2018 TSH58p_11840 2872f50daafdc15f44fad032acff4602 142 SUPERFAMILY SSF54631 5 135 2.15E-31 T 14-10-2018 TSH58p_11840 2872f50daafdc15f44fad032acff4602 142 SMART SM00116 14 61 1.4E-10 T 14-10-2018 IPR000644 CBS domain TSH58p_11840 2872f50daafdc15f44fad032acff4602 142 SMART SM00116 79 126 7.7E-5 T 14-10-2018 IPR000644 CBS domain TSH58p_28435 c1320e122ff7b536ef4a954ed5dd6554 328 Gene3D G3DSA:3.40.50.720 15 305 1.8E-106 T 14-10-2018 TSH58p_28435 c1320e122ff7b536ef4a954ed5dd6554 328 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 120 296 4.7E-55 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TSH58p_28435 c1320e122ff7b536ef4a954ed5dd6554 328 SUPERFAMILY SSF51735 111 297 3.41E-59 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_28435 c1320e122ff7b536ef4a954ed5dd6554 328 Gene3D G3DSA:3.40.50.720 111 297 1.8E-106 T 14-10-2018 TSH58p_28435 c1320e122ff7b536ef4a954ed5dd6554 328 SUPERFAMILY SSF52283 9 145 1.36E-29 T 14-10-2018 TSH58p_28435 c1320e122ff7b536ef4a954ed5dd6554 328 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 38 327 7.1E-26 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 TSH58p_28435 c1320e122ff7b536ef4a954ed5dd6554 328 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 236 252 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TSH58p_16320 8a57e1c883b6300dbfa9ad9b087817f7 158 Gene3D G3DSA:3.30.1330.60 27 157 2.8E-40 T 14-10-2018 IPR036737 OmpA-like domain superfamily TSH58p_16320 8a57e1c883b6300dbfa9ad9b087817f7 158 SUPERFAMILY SSF103088 45 154 3.4E-37 T 14-10-2018 IPR036737 OmpA-like domain superfamily TSH58p_16320 8a57e1c883b6300dbfa9ad9b087817f7 158 Hamap MF_02204 Peptidoglycan-associated lipoprotein [pal]. 1 157 31.732 T 14-10-2018 IPR039001 Peptidoglycan-associated lipoprotein GO:0009279|GO:0051301 TSH58p_16320 8a57e1c883b6300dbfa9ad9b087817f7 158 Pfam PF00691 OmpA family 56 151 5.5E-23 T 14-10-2018 IPR006665 OmpA-like domain TSH58p_16320 8a57e1c883b6300dbfa9ad9b087817f7 158 ProSitePatterns PS01068 OmpA-like domain. 89 133 - T 14-10-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 TSH58p_16320 8a57e1c883b6300dbfa9ad9b087817f7 158 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 54 156 4.4E-44 T 14-10-2018 IPR014169 Peptidoglycan-associated lipoprotein, C-terminal GO:0009279 TSH58p_16320 8a57e1c883b6300dbfa9ad9b087817f7 158 PRINTS PR01021 OMPA domain signature 57 79 3.8E-19 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 TSH58p_16320 8a57e1c883b6300dbfa9ad9b087817f7 158 PRINTS PR01021 OMPA domain signature 87 102 3.8E-19 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 TSH58p_16320 8a57e1c883b6300dbfa9ad9b087817f7 158 PRINTS PR01021 OMPA domain signature 102 118 3.8E-19 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 TSH58p_12630 d80db6788bcc6154262e657356176f23 339 SUPERFAMILY SSF53335 107 324 2.48E-23 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_12630 d80db6788bcc6154262e657356176f23 339 Gene3D G3DSA:3.40.50.150 104 338 8.6E-20 T 14-10-2018 TSH58p_12630 d80db6788bcc6154262e657356176f23 339 Pfam PF13489 Methyltransferase domain 123 271 1.8E-8 T 14-10-2018 TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 TIGRFAM TIGR00593 pola: DNA polymerase I 26 970 3.7E-279 T 14-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 PRINTS PR00868 DNA-polymerase family A (pol I) signature 886 902 4.1E-70 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 PRINTS PR00868 DNA-polymerase family A (pol I) signature 771 784 4.1E-70 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 PRINTS PR00868 DNA-polymerase family A (pol I) signature 719 734 4.1E-70 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 PRINTS PR00868 DNA-polymerase family A (pol I) signature 917 930 4.1E-70 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 PRINTS PR00868 DNA-polymerase family A (pol I) signature 696 718 4.1E-70 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 PRINTS PR00868 DNA-polymerase family A (pol I) signature 832 843 4.1E-70 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 PRINTS PR00868 DNA-polymerase family A (pol I) signature 854 865 4.1E-70 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 PRINTS PR00868 DNA-polymerase family A (pol I) signature 741 764 4.1E-70 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 PRINTS PR00868 DNA-polymerase family A (pol I) signature 795 820 4.1E-70 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 SUPERFAMILY SSF47807 188 303 2.39E-29 T 14-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 SMART SM00475 24 279 2.0E-117 T 14-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 SUPERFAMILY SSF56672 562 970 2.45E-146 T 14-10-2018 TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 SMART SM00474 359 558 3.3E-34 T 14-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 Pfam PF00476 DNA polymerase family A 591 968 8.1E-143 T 14-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 SUPERFAMILY SSF53098 356 557 2.94E-48 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 SMART SM00482 727 934 3.9E-104 T 14-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 Gene3D G3DSA:3.30.70.370 705 966 2.3E-104 T 14-10-2018 TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 Gene3D G3DSA:1.10.150.20 750 893 2.3E-104 T 14-10-2018 TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 SUPERFAMILY SSF88723 25 187 7.85E-53 T 14-10-2018 IPR029060 PIN-like domain superfamily TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 Gene3D G3DSA:3.30.420.10 356 581 4.0E-65 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 Gene3D G3DSA:3.40.50.1010 26 295 4.3E-93 T 14-10-2018 TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 Gene3D G3DSA:1.20.1060.10 583 699 9.7E-38 T 14-10-2018 TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 188 283 1.5E-29 T 14-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 26 187 4.6E-56 T 14-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 SMART SM00279 190 225 1.7E-13 T 14-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 Pfam PF01612 3'-5' exonuclease 359 557 2.4E-33 T 14-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 ProSitePatterns PS00447 DNA polymerase family A signature. 795 814 - T 14-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSH58p_20460 fc490afd144dbc0519a81deca22996b4 970 Gene3D G3DSA:1.10.150.20 191 264 4.3E-93 T 14-10-2018 TSH58p_01600 b052445d16820577326d83aab651d460 172 Pfam PF08281 Sigma-70, region 4 111 162 5.1E-14 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_01600 b052445d16820577326d83aab651d460 172 SUPERFAMILY SSF88659 90 167 2.06E-14 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSH58p_01600 b052445d16820577326d83aab651d460 172 Gene3D G3DSA:1.10.10.10 95 168 7.8E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_01600 b052445d16820577326d83aab651d460 172 Gene3D G3DSA:1.10.1740.10 2 82 5.0E-10 T 14-10-2018 TSH58p_01600 b052445d16820577326d83aab651d460 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 163 3.1E-23 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TSH58p_01600 b052445d16820577326d83aab651d460 172 Pfam PF04542 Sigma-70 region 2 10 78 1.5E-11 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_01600 b052445d16820577326d83aab651d460 172 SUPERFAMILY SSF88946 9 93 8.63E-14 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_07490 558edcc0c8efc9864f80449a336461c5 495 SUPERFAMILY SSF56176 15 227 1.64E-68 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TSH58p_07490 558edcc0c8efc9864f80449a336461c5 495 Pfam PF02913 FAD linked oxidases, C-terminal domain 226 467 8.5E-66 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 TSH58p_07490 558edcc0c8efc9864f80449a336461c5 495 Gene3D G3DSA:3.30.465.40 15 235 1.4E-63 T 14-10-2018 TSH58p_07490 558edcc0c8efc9864f80449a336461c5 495 Gene3D G3DSA:3.30.70.2740 346 427 3.9E-6 T 14-10-2018 TSH58p_07490 558edcc0c8efc9864f80449a336461c5 495 SUPERFAMILY SSF55103 200 469 7.85E-73 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 TSH58p_07490 558edcc0c8efc9864f80449a336461c5 495 Pfam PF01565 FAD binding domain 52 191 3.3E-38 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TSH58p_07490 558edcc0c8efc9864f80449a336461c5 495 Gene3D G3DSA:1.10.45.10 428 468 1.6E-13 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 TSH58p_19910 86bdad48c4b5fab5e4fed3a83aed732b 127 SUPERFAMILY SSF54593 9 121 6.04E-24 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSH58p_19910 86bdad48c4b5fab5e4fed3a83aed732b 127 Gene3D G3DSA:3.10.180.10 2 121 6.3E-33 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSH58p_19910 86bdad48c4b5fab5e4fed3a83aed732b 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 118 1.6E-5 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TSH58p_24430 527f4041d2c1d0204e1ee03aadf77175 144 Pfam PF00376 MerR family regulatory protein 7 44 7.3E-16 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_24430 527f4041d2c1d0204e1ee03aadf77175 144 ProSitePatterns PS00552 MerR-type HTH domain signature. 9 31 - T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_24430 527f4041d2c1d0204e1ee03aadf77175 144 SUPERFAMILY SSF46955 6 131 6.59E-38 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily TSH58p_24430 527f4041d2c1d0204e1ee03aadf77175 144 SMART SM00422 6 75 7.9E-29 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_24430 527f4041d2c1d0204e1ee03aadf77175 144 TIGRFAM TIGR02044 CueR: Cu(I)-responsive transcriptional regulator 6 131 8.0E-51 T 14-10-2018 IPR011789 Cu(I)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0005507|GO:0045893 TSH58p_24430 527f4041d2c1d0204e1ee03aadf77175 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 7 18 2.3E-13 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_24430 527f4041d2c1d0204e1ee03aadf77175 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 42 62 2.3E-13 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_24430 527f4041d2c1d0204e1ee03aadf77175 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 18 31 2.3E-13 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_24430 527f4041d2c1d0204e1ee03aadf77175 144 Gene3D G3DSA:1.10.1660.10 3 130 1.5E-34 T 14-10-2018 TSH58p_24430 527f4041d2c1d0204e1ee03aadf77175 144 Pfam PF09278 MerR, DNA binding 52 113 3.7E-18 T 14-10-2018 IPR015358 Transcription regulator MerR, DNA binding TSH58p_13655 245b09416e058c82ca8479212d39e61d 509 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 509 51.647 T 14-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_13655 245b09416e058c82ca8479212d39e61d 509 Gene3D G3DSA:3.40.50.300 94 379 1.0E-131 T 14-10-2018 TSH58p_13655 245b09416e058c82ca8479212d39e61d 509 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 25 92 2.3E-16 T 14-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSH58p_13655 245b09416e058c82ca8479212d39e61d 509 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 379 504 3.1E-48 T 14-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_13655 245b09416e058c82ca8479212d39e61d 509 PIRSF PIRSF039088 1 509 2.2E-284 T 14-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_13655 245b09416e058c82ca8479212d39e61d 509 SUPERFAMILY SSF47917 380 508 1.67E-46 T 14-10-2018 TSH58p_13655 245b09416e058c82ca8479212d39e61d 509 Gene3D G3DSA:2.40.30.20 1 93 6.0E-40 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSH58p_13655 245b09416e058c82ca8479212d39e61d 509 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 372 1.4E-72 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSH58p_13655 245b09416e058c82ca8479212d39e61d 509 SUPERFAMILY SSF50615 10 94 6.8E-30 T 14-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSH58p_13655 245b09416e058c82ca8479212d39e61d 509 SUPERFAMILY SSF52540 96 378 8.35E-102 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_13655 245b09416e058c82ca8479212d39e61d 509 Gene3D G3DSA:1.20.150.20 380 509 2.1E-53 T 14-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_13655 245b09416e058c82ca8479212d39e61d 509 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 363 372 - T 14-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSH58p_13655 245b09416e058c82ca8479212d39e61d 509 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 508 2.1E-253 T 14-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_07830 73b567b3810f7ea05900f237f943c385 133 SUPERFAMILY SSF55248 19 112 4.05E-28 T 14-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 TSH58p_07830 73b567b3810f7ea05900f237f943c385 133 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 21 109 1.8E-26 T 14-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 TSH58p_07830 73b567b3810f7ea05900f237f943c385 133 Gene3D G3DSA:3.30.1360.20 22 117 1.3E-26 T 14-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 TSH58p_02775 009c24c8e488fe3efe7ac8077ce7e234 424 Gene3D G3DSA:3.40.630.10 25 418 4.0E-151 T 14-10-2018 TSH58p_02775 009c24c8e488fe3efe7ac8077ce7e234 424 Gene3D G3DSA:3.30.70.360 203 330 4.0E-151 T 14-10-2018 TSH58p_02775 009c24c8e488fe3efe7ac8077ce7e234 424 Pfam PF01546 Peptidase family M20/M25/M40 96 413 1.8E-36 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 TSH58p_02775 009c24c8e488fe3efe7ac8077ce7e234 424 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 18 408 1.1E-87 T 14-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase TSH58p_02775 009c24c8e488fe3efe7ac8077ce7e234 424 SUPERFAMILY SSF53187 5 418 6.0E-60 T 14-10-2018 TSH58p_02775 009c24c8e488fe3efe7ac8077ce7e234 424 SUPERFAMILY SSF55031 203 312 1.45E-11 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TSH58p_02775 009c24c8e488fe3efe7ac8077ce7e234 424 Pfam PF07687 Peptidase dimerisation domain 200 312 5.2E-17 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain TSH58p_04345 f7233706558c65d3c6eeee7eceafa43f 295 Pfam PF00581 Rhodanese-like domain 166 281 1.5E-11 T 14-10-2018 IPR001763 Rhodanese-like domain TSH58p_04345 f7233706558c65d3c6eeee7eceafa43f 295 Pfam PF00581 Rhodanese-like domain 18 137 1.1E-15 T 14-10-2018 IPR001763 Rhodanese-like domain TSH58p_04345 f7233706558c65d3c6eeee7eceafa43f 295 SMART SM00450 164 286 1.9E-17 T 14-10-2018 IPR001763 Rhodanese-like domain TSH58p_04345 f7233706558c65d3c6eeee7eceafa43f 295 SMART SM00450 15 141 7.0E-22 T 14-10-2018 IPR001763 Rhodanese-like domain TSH58p_04345 f7233706558c65d3c6eeee7eceafa43f 295 Gene3D G3DSA:3.40.250.10 8 158 1.1E-48 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily TSH58p_04345 f7233706558c65d3c6eeee7eceafa43f 295 SUPERFAMILY SSF52821 12 162 4.58E-43 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily TSH58p_04345 f7233706558c65d3c6eeee7eceafa43f 295 ProSitePatterns PS00683 Rhodanese C-terminal signature. 270 280 - T 14-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 TSH58p_04345 f7233706558c65d3c6eeee7eceafa43f 295 Gene3D G3DSA:3.40.250.10 162 286 3.8E-38 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily TSH58p_04345 f7233706558c65d3c6eeee7eceafa43f 295 ProSitePatterns PS00380 Rhodanese signature 1. 49 60 - T 14-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 TSH58p_04345 f7233706558c65d3c6eeee7eceafa43f 295 SUPERFAMILY SSF52821 166 294 9.17E-34 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily TSH58p_26670 ae2656e3e8bf76b8028ed408e38ddec2 526 Gene3D G3DSA:3.40.309.10 268 456 3.4E-211 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TSH58p_26670 ae2656e3e8bf76b8028ed408e38ddec2 526 Pfam PF00171 Aldehyde dehydrogenase family 19 459 3.2E-44 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TSH58p_26670 ae2656e3e8bf76b8028ed408e38ddec2 526 Gene3D G3DSA:3.40.605.10 43 521 3.4E-211 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TSH58p_26670 ae2656e3e8bf76b8028ed408e38ddec2 526 SUPERFAMILY SSF53720 19 519 6.02E-102 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSH58p_21755 bce1edf2fb31b87ca02c1ac085750d55 320 SUPERFAMILY SSF46785 1 111 1.26E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_21755 bce1edf2fb31b87ca02c1ac085750d55 320 Pfam PF03466 LysR substrate binding domain 88 286 2.7E-36 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_21755 bce1edf2fb31b87ca02c1ac085750d55 320 Gene3D G3DSA:1.10.10.10 1 84 4.1E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_21755 bce1edf2fb31b87ca02c1ac085750d55 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 7.8E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_21755 bce1edf2fb31b87ca02c1ac085750d55 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 7.8E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_21755 bce1edf2fb31b87ca02c1ac085750d55 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 7.8E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_21755 bce1edf2fb31b87ca02c1ac085750d55 320 SUPERFAMILY SSF53850 89 294 1.56E-36 T 14-10-2018 TSH58p_21755 bce1edf2fb31b87ca02c1ac085750d55 320 Gene3D G3DSA:3.40.190.290 90 289 1.3E-27 T 14-10-2018 TSH58p_21755 bce1edf2fb31b87ca02c1ac085750d55 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.9E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_24020 871a611a9c744e9088ff118f63fe7fa8 240 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_24020 871a611a9c744e9088ff118f63fe7fa8 240 Gene3D G3DSA:3.40.50.300 7 240 5.9E-54 T 14-10-2018 TSH58p_24020 871a611a9c744e9088ff118f63fe7fa8 240 Pfam PF00005 ABC transporter 27 168 4.0E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_24020 871a611a9c744e9088ff118f63fe7fa8 240 SMART SM00382 36 217 2.9E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_24020 871a611a9c744e9088ff118f63fe7fa8 240 SUPERFAMILY SSF52540 11 237 2.25E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_31560 950b1af3d914acaac0b6032bbd37930e 137 Pfam PF12903 Protein of unknown function (DUF3830) 11 135 7.4E-31 T 14-10-2018 IPR024532 Protein of unknown function DUF3830 TSH58p_31560 950b1af3d914acaac0b6032bbd37930e 137 Gene3D G3DSA:2.40.100.20 3 137 8.8E-35 T 14-10-2018 TSH58p_15155 6c02d3cb192688410dbd6a635edcebcb 396 Gene3D G3DSA:3.40.50.300 1 205 8.9E-71 T 14-10-2018 TSH58p_15155 6c02d3cb192688410dbd6a635edcebcb 396 SUPERFAMILY SSF50465 300 395 5.47E-35 T 14-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal TSH58p_15155 6c02d3cb192688410dbd6a635edcebcb 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 1.3E-16 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TSH58p_15155 6c02d3cb192688410dbd6a635edcebcb 396 Gene3D G3DSA:2.40.30.10 209 336 6.2E-52 T 14-10-2018 TSH58p_15155 6c02d3cb192688410dbd6a635edcebcb 396 Gene3D G3DSA:2.40.30.10 340 395 2.7E-28 T 14-10-2018 TSH58p_15155 6c02d3cb192688410dbd6a635edcebcb 396 SUPERFAMILY SSF52540 9 228 6.54E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_15155 6c02d3cb192688410dbd6a635edcebcb 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 2.3E-228 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TSH58p_15155 6c02d3cb192688410dbd6a635edcebcb 396 SUPERFAMILY SSF50447 205 303 1.24E-30 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSH58p_15155 6c02d3cb192688410dbd6a635edcebcb 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site TSH58p_15155 6c02d3cb192688410dbd6a635edcebcb 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 4.0E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_15155 6c02d3cb192688410dbd6a635edcebcb 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 4.0E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_15155 6c02d3cb192688410dbd6a635edcebcb 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 4.0E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_15155 6c02d3cb192688410dbd6a635edcebcb 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.0E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_15155 6c02d3cb192688410dbd6a635edcebcb 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 4.0E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_15155 6c02d3cb192688410dbd6a635edcebcb 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.145 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TSH58p_15155 6c02d3cb192688410dbd6a635edcebcb 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 2.3E-57 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_15155 6c02d3cb192688410dbd6a635edcebcb 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 150 1.4E-14 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSH58p_15155 6c02d3cb192688410dbd6a635edcebcb 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 2.9E-33 T 14-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal TSH58p_15085 6c02d3cb192688410dbd6a635edcebcb 396 Gene3D G3DSA:3.40.50.300 1 205 8.9E-71 T 14-10-2018 TSH58p_15085 6c02d3cb192688410dbd6a635edcebcb 396 SUPERFAMILY SSF50465 300 395 5.47E-35 T 14-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal TSH58p_15085 6c02d3cb192688410dbd6a635edcebcb 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 1.3E-16 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TSH58p_15085 6c02d3cb192688410dbd6a635edcebcb 396 Gene3D G3DSA:2.40.30.10 209 336 6.2E-52 T 14-10-2018 TSH58p_15085 6c02d3cb192688410dbd6a635edcebcb 396 Gene3D G3DSA:2.40.30.10 340 395 2.7E-28 T 14-10-2018 TSH58p_15085 6c02d3cb192688410dbd6a635edcebcb 396 SUPERFAMILY SSF52540 9 228 6.54E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_15085 6c02d3cb192688410dbd6a635edcebcb 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 2.3E-228 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TSH58p_15085 6c02d3cb192688410dbd6a635edcebcb 396 SUPERFAMILY SSF50447 205 303 1.24E-30 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSH58p_15085 6c02d3cb192688410dbd6a635edcebcb 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site TSH58p_15085 6c02d3cb192688410dbd6a635edcebcb 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 4.0E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_15085 6c02d3cb192688410dbd6a635edcebcb 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 4.0E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_15085 6c02d3cb192688410dbd6a635edcebcb 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 4.0E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_15085 6c02d3cb192688410dbd6a635edcebcb 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.0E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_15085 6c02d3cb192688410dbd6a635edcebcb 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 4.0E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_15085 6c02d3cb192688410dbd6a635edcebcb 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.145 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TSH58p_15085 6c02d3cb192688410dbd6a635edcebcb 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 2.3E-57 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_15085 6c02d3cb192688410dbd6a635edcebcb 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 150 1.4E-14 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSH58p_15085 6c02d3cb192688410dbd6a635edcebcb 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 2.9E-33 T 14-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal TSH58p_29880 0b4f14dfa4856879b1d01c4a7c99a186 465 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 TSH58p_29880 0b4f14dfa4856879b1d01c4a7c99a186 465 SUPERFAMILY SSF51230 1 95 3.01E-28 T 14-10-2018 IPR011053 Single hybrid motif TSH58p_29880 0b4f14dfa4856879b1d01c4a7c99a186 465 SMART SM00861 142 317 1.7E-57 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSH58p_29880 0b4f14dfa4856879b1d01c4a7c99a186 465 Gene3D G3DSA:2.40.50.100 2 99 2.1E-32 T 14-10-2018 TSH58p_29880 0b4f14dfa4856879b1d01c4a7c99a186 465 Gene3D G3DSA:3.40.50.970 141 328 1.8E-83 T 14-10-2018 TSH58p_29880 0b4f14dfa4856879b1d01c4a7c99a186 465 Gene3D G3DSA:3.40.50.920 329 462 3.0E-52 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSH58p_29880 0b4f14dfa4856879b1d01c4a7c99a186 465 Pfam PF02780 Transketolase, C-terminal domain 332 454 2.5E-45 T 14-10-2018 IPR033248 Transketolase, C-terminal domain TSH58p_29880 0b4f14dfa4856879b1d01c4a7c99a186 465 SUPERFAMILY SSF52922 326 461 7.07E-46 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSH58p_29880 0b4f14dfa4856879b1d01c4a7c99a186 465 Pfam PF02779 Transketolase, pyrimidine binding domain 142 316 3.2E-47 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSH58p_29880 0b4f14dfa4856879b1d01c4a7c99a186 465 Pfam PF00364 Biotin-requiring enzyme 4 77 6.4E-20 T 14-10-2018 IPR000089 Biotin/lipoyl attachment TSH58p_29880 0b4f14dfa4856879b1d01c4a7c99a186 465 SUPERFAMILY SSF52518 142 331 2.9E-66 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_31610 d02c6360f0710b7f5fe080530b091735 495 SMART SM00387 363 471 4.3E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_31610 d02c6360f0710b7f5fe080530b091735 495 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 363 462 3.5E-14 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_31610 d02c6360f0710b7f5fe080530b091735 495 Gene3D G3DSA:1.10.287.130 203 317 8.5E-15 T 14-10-2018 TSH58p_31610 d02c6360f0710b7f5fe080530b091735 495 Gene3D G3DSA:3.30.565.10 320 472 3.9E-27 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_31610 d02c6360f0710b7f5fe080530b091735 495 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 413 6.9E-5 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_31610 d02c6360f0710b7f5fe080530b091735 495 PRINTS PR00344 Bacterial sensor protein C-terminal signature 432 450 6.9E-5 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_31610 d02c6360f0710b7f5fe080530b091735 495 SMART SM00388 253 318 3.9E-4 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_31610 d02c6360f0710b7f5fe080530b091735 495 SUPERFAMILY SSF47384 236 318 3.53E-10 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_31610 d02c6360f0710b7f5fe080530b091735 495 SUPERFAMILY SSF55874 310 467 1.96E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_31610 d02c6360f0710b7f5fe080530b091735 495 SMART SM00304 199 252 1.7E-5 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_00050 49a93c3f25959ef547765a8f2385b243 1022 Gene3D G3DSA:1.20.120.160 813 928 9.6E-19 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_00050 49a93c3f25959ef547765a8f2385b243 1022 SUPERFAMILY SSF47226 763 909 2.22E-18 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_00050 49a93c3f25959ef547765a8f2385b243 1022 Pfam PF01627 Hpt domain 836 922 2.9E-11 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TSH58p_00050 49a93c3f25959ef547765a8f2385b243 1022 SMART SM00387 387 503 6.3E-36 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_00050 49a93c3f25959ef547765a8f2385b243 1022 SUPERFAMILY SSF55874 329 498 9.3E-41 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_00050 49a93c3f25959ef547765a8f2385b243 1022 SMART SM00388 275 340 1.3E-23 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_00050 49a93c3f25959ef547765a8f2385b243 1022 Pfam PF00512 His Kinase A (phospho-acceptor) domain 276 340 4.1E-19 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_00050 49a93c3f25959ef547765a8f2385b243 1022 Gene3D G3DSA:3.40.50.2300 667 788 4.4E-39 T 14-10-2018 TSH58p_00050 49a93c3f25959ef547765a8f2385b243 1022 Pfam PF00072 Response regulator receiver domain 670 778 5.6E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_00050 49a93c3f25959ef547765a8f2385b243 1022 Pfam PF00072 Response regulator receiver domain 522 635 9.0E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_00050 49a93c3f25959ef547765a8f2385b243 1022 SMART SM00448 519 637 6.1E-17 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_00050 49a93c3f25959ef547765a8f2385b243 1022 SMART SM00448 668 780 9.3E-35 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_00050 49a93c3f25959ef547765a8f2385b243 1022 SMART SM00073 825 923 6.7E-8 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TSH58p_00050 49a93c3f25959ef547765a8f2385b243 1022 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 387 501 1.6E-27 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_00050 49a93c3f25959ef547765a8f2385b243 1022 Gene3D G3DSA:3.40.50.12740 519 666 3.6E-23 T 14-10-2018 TSH58p_00050 49a93c3f25959ef547765a8f2385b243 1022 SUPERFAMILY SSF47384 260 341 4.9E-21 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_00050 49a93c3f25959ef547765a8f2385b243 1022 Gene3D G3DSA:1.10.287.130 244 338 1.3E-28 T 14-10-2018 TSH58p_00050 49a93c3f25959ef547765a8f2385b243 1022 Gene3D G3DSA:3.30.565.10 339 504 4.0E-48 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_00050 49a93c3f25959ef547765a8f2385b243 1022 SUPERFAMILY SSF52172 666 785 9.11E-38 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_00050 49a93c3f25959ef547765a8f2385b243 1022 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 481 2.1E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_00050 49a93c3f25959ef547765a8f2385b243 1022 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 456 2.1E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_00050 49a93c3f25959ef547765a8f2385b243 1022 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 442 2.1E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_00050 49a93c3f25959ef547765a8f2385b243 1022 PRINTS PR00344 Bacterial sensor protein C-terminal signature 487 500 2.1E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_00050 49a93c3f25959ef547765a8f2385b243 1022 SUPERFAMILY SSF52172 515 642 1.71E-23 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_03410 49a93c3f25959ef547765a8f2385b243 1022 Gene3D G3DSA:1.20.120.160 813 928 9.6E-19 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_03410 49a93c3f25959ef547765a8f2385b243 1022 SUPERFAMILY SSF47226 763 909 2.22E-18 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_03410 49a93c3f25959ef547765a8f2385b243 1022 Pfam PF01627 Hpt domain 836 922 2.9E-11 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TSH58p_03410 49a93c3f25959ef547765a8f2385b243 1022 SMART SM00387 387 503 6.3E-36 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_03410 49a93c3f25959ef547765a8f2385b243 1022 SUPERFAMILY SSF55874 329 498 9.3E-41 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_03410 49a93c3f25959ef547765a8f2385b243 1022 SMART SM00388 275 340 1.3E-23 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_03410 49a93c3f25959ef547765a8f2385b243 1022 Pfam PF00512 His Kinase A (phospho-acceptor) domain 276 340 4.1E-19 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_03410 49a93c3f25959ef547765a8f2385b243 1022 Gene3D G3DSA:3.40.50.2300 667 788 4.4E-39 T 14-10-2018 TSH58p_03410 49a93c3f25959ef547765a8f2385b243 1022 Pfam PF00072 Response regulator receiver domain 670 778 5.6E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_03410 49a93c3f25959ef547765a8f2385b243 1022 Pfam PF00072 Response regulator receiver domain 522 635 9.0E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_03410 49a93c3f25959ef547765a8f2385b243 1022 SMART SM00448 519 637 6.1E-17 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_03410 49a93c3f25959ef547765a8f2385b243 1022 SMART SM00448 668 780 9.3E-35 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_03410 49a93c3f25959ef547765a8f2385b243 1022 SMART SM00073 825 923 6.7E-8 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TSH58p_03410 49a93c3f25959ef547765a8f2385b243 1022 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 387 501 1.6E-27 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_03410 49a93c3f25959ef547765a8f2385b243 1022 Gene3D G3DSA:3.40.50.12740 519 666 3.6E-23 T 14-10-2018 TSH58p_03410 49a93c3f25959ef547765a8f2385b243 1022 SUPERFAMILY SSF47384 260 341 4.9E-21 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_03410 49a93c3f25959ef547765a8f2385b243 1022 Gene3D G3DSA:1.10.287.130 244 338 1.3E-28 T 14-10-2018 TSH58p_03410 49a93c3f25959ef547765a8f2385b243 1022 Gene3D G3DSA:3.30.565.10 339 504 4.0E-48 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_03410 49a93c3f25959ef547765a8f2385b243 1022 SUPERFAMILY SSF52172 666 785 9.11E-38 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_03410 49a93c3f25959ef547765a8f2385b243 1022 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 481 2.1E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_03410 49a93c3f25959ef547765a8f2385b243 1022 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 456 2.1E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_03410 49a93c3f25959ef547765a8f2385b243 1022 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 442 2.1E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_03410 49a93c3f25959ef547765a8f2385b243 1022 PRINTS PR00344 Bacterial sensor protein C-terminal signature 487 500 2.1E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_03410 49a93c3f25959ef547765a8f2385b243 1022 SUPERFAMILY SSF52172 515 642 1.71E-23 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_10285 2285d3d6b30b121e9c1268e311ca22e4 414 Gene3D G3DSA:3.50.50.60 19 401 4.0E-71 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_10285 2285d3d6b30b121e9c1268e311ca22e4 414 Gene3D G3DSA:1.10.8.260 283 337 4.0E-71 T 14-10-2018 IPR023166 HI0933-like insert domain superfamily TSH58p_10285 2285d3d6b30b121e9c1268e311ca22e4 414 Pfam PF03486 HI0933-like protein 16 406 1.1E-103 T 14-10-2018 TSH58p_10285 2285d3d6b30b121e9c1268e311ca22e4 414 PRINTS PR00419 Adrenodoxin reductase family signature 16 38 1.6E-6 T 14-10-2018 TSH58p_10285 2285d3d6b30b121e9c1268e311ca22e4 414 PRINTS PR00419 Adrenodoxin reductase family signature 39 52 1.6E-6 T 14-10-2018 TSH58p_10285 2285d3d6b30b121e9c1268e311ca22e4 414 Gene3D G3DSA:2.40.30.10 204 354 4.0E-71 T 14-10-2018 TSH58p_10285 2285d3d6b30b121e9c1268e311ca22e4 414 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 17 406 3.7E-88 T 14-10-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like TSH58p_10285 2285d3d6b30b121e9c1268e311ca22e4 414 SUPERFAMILY SSF160996 209 353 2.09E-13 T 14-10-2018 TSH58p_10285 2285d3d6b30b121e9c1268e311ca22e4 414 SUPERFAMILY SSF51905 16 412 1.51E-44 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_10285 2285d3d6b30b121e9c1268e311ca22e4 414 TIGRFAM TIGR03862 flavo_PP4765: flavoprotein, TIGR03862 family 39 412 4.8E-148 T 14-10-2018 IPR022460 Conserved hyptotheical protein CHP03862, flavoprotein, PP4765 TSH58p_28160 a492bc9d0cdbad23ff1f0ca0683fa80f 922 Gene3D G3DSA:3.20.20.80 9 100 2.3E-25 T 14-10-2018 TSH58p_28160 a492bc9d0cdbad23ff1f0ca0683fa80f 922 Gene3D G3DSA:3.30.1590.10 101 211 4.2E-19 T 14-10-2018 TSH58p_28160 a492bc9d0cdbad23ff1f0ca0683fa80f 922 SMART SM00642 23 632 1.2E-5 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSH58p_28160 a492bc9d0cdbad23ff1f0ca0683fa80f 922 Pfam PF00128 Alpha amylase, catalytic domain 32 100 2.4E-14 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSH58p_28160 a492bc9d0cdbad23ff1f0ca0683fa80f 922 Gene3D G3DSA:3.20.20.80 271 449 4.4E-37 T 14-10-2018 TSH58p_28160 a492bc9d0cdbad23ff1f0ca0683fa80f 922 Gene3D G3DSA:3.20.20.80 478 632 2.0E-6 T 14-10-2018 TSH58p_28160 a492bc9d0cdbad23ff1f0ca0683fa80f 922 Gene3D G3DSA:3.20.20.80 670 833 3.0E-42 T 14-10-2018 TSH58p_28160 a492bc9d0cdbad23ff1f0ca0683fa80f 922 SUPERFAMILY SSF51445 10 829 1.27E-130 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_28160 a492bc9d0cdbad23ff1f0ca0683fa80f 922 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 10 920 3.1E-302 T 14-10-2018 IPR012767 Maltooligosyl trehalose synthase KEGG: 00500+5.4.99.15|MetaCyc: PWY-2661 TSH58p_26975 90166dbeaac3f72b9768d1a8de6c8d25 392 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 392 84.64 T 14-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 TSH58p_26975 90166dbeaac3f72b9768d1a8de6c8d25 392 ProSitePatterns PS00617 RecF protein signature 1. 139 159 - T 14-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 TSH58p_26975 90166dbeaac3f72b9768d1a8de6c8d25 392 Gene3D G3DSA:1.20.1050.90 142 332 1.0E-75 T 14-10-2018 TSH58p_26975 90166dbeaac3f72b9768d1a8de6c8d25 392 ProSitePatterns PS00618 RecF protein signature 2. 333 351 - T 14-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 TSH58p_26975 90166dbeaac3f72b9768d1a8de6c8d25 392 Pfam PF02463 RecF/RecN/SMC N terminal domain 9 356 2.1E-14 T 14-10-2018 IPR003395 RecF/RecN/SMC, N-terminal TSH58p_26975 90166dbeaac3f72b9768d1a8de6c8d25 392 SUPERFAMILY SSF52540 10 371 9.31E-35 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_26975 90166dbeaac3f72b9768d1a8de6c8d25 392 SMART SM00382 28 388 9.8E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_26975 90166dbeaac3f72b9768d1a8de6c8d25 392 Gene3D G3DSA:3.40.50.300 12 368 1.0E-75 T 14-10-2018 TSH58p_01945 451f488eeb2aaaf4125615d287da7c83 750 Gene3D G3DSA:3.40.50.300 480 740 1.9E-60 T 14-10-2018 TSH58p_01945 451f488eeb2aaaf4125615d287da7c83 750 Pfam PF13807 G-rich domain on putative tyrosine kinase 412 485 5.1E-10 T 14-10-2018 IPR032807 Tyrosine kinase, G-rich domain TSH58p_01945 451f488eeb2aaaf4125615d287da7c83 750 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 555 727 1.0E-7 T 14-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TSH58p_01945 451f488eeb2aaaf4125615d287da7c83 750 Pfam PF02706 Chain length determinant protein 19 109 5.1E-8 T 14-10-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 TSH58p_01945 451f488eeb2aaaf4125615d287da7c83 750 SUPERFAMILY SSF52540 554 728 4.09E-33 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_00455 4b6321bbabd9a542ac9ea2672bd45639 393 Pfam PF02803 Thiolase, C-terminal domain 271 391 1.4E-43 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 TSH58p_00455 4b6321bbabd9a542ac9ea2672bd45639 393 Pfam PF00108 Thiolase, N-terminal domain 5 262 2.8E-87 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 TSH58p_00455 4b6321bbabd9a542ac9ea2672bd45639 393 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 14-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 TSH58p_00455 4b6321bbabd9a542ac9ea2672bd45639 393 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 14-10-2018 IPR020610 Thiolase, active site GO:0016747 TSH58p_00455 4b6321bbabd9a542ac9ea2672bd45639 393 SUPERFAMILY SSF53901 5 270 1.37E-79 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_00455 4b6321bbabd9a542ac9ea2672bd45639 393 Gene3D G3DSA:3.40.47.10 127 389 6.7E-142 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_00455 4b6321bbabd9a542ac9ea2672bd45639 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 391 1.7E-126 T 14-10-2018 IPR002155 Thiolase GO:0016747 TSH58p_00455 4b6321bbabd9a542ac9ea2672bd45639 393 PIRSF PIRSF000429 1 393 6.1E-111 T 14-10-2018 IPR002155 Thiolase GO:0016747 TSH58p_00455 4b6321bbabd9a542ac9ea2672bd45639 393 Gene3D G3DSA:3.40.47.10 6 276 6.7E-142 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_00455 4b6321bbabd9a542ac9ea2672bd45639 393 SUPERFAMILY SSF53901 272 392 7.88E-41 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_02445 2508bf80925f7ec385d64971f210b23b 346 PIRSF PIRSF006470 1 339 2.3E-75 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 TSH58p_02445 2508bf80925f7ec385d64971f210b23b 346 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 49 321 5.4E-62 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 TSH58p_02445 2508bf80925f7ec385d64971f210b23b 346 Gene3D G3DSA:3.40.190.170 27 336 2.1E-77 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily TSH58p_02445 2508bf80925f7ec385d64971f210b23b 346 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 48 266 3.4E-52 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 TSH58p_15390 1b47747c970bcbe68ae0abe96940c693 139 SUPERFAMILY SSF109635 5 97 1.7E-32 T 14-10-2018 IPR037187 DksA, N-terminal domain superfamily TSH58p_15390 1b47747c970bcbe68ae0abe96940c693 139 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 15 137 27.979 T 14-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 TSH58p_15390 1b47747c970bcbe68ae0abe96940c693 139 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 96 131 6.4E-11 T 14-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 TSH58p_15390 1b47747c970bcbe68ae0abe96940c693 139 Gene3D G3DSA:1.20.120.910 6 139 1.7E-37 T 14-10-2018 TSH58p_15390 1b47747c970bcbe68ae0abe96940c693 139 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 101 125 - T 14-10-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site TSH58p_15390 1b47747c970bcbe68ae0abe96940c693 139 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 19 128 3.5E-43 T 14-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 TSH58p_15390 1b47747c970bcbe68ae0abe96940c693 139 SUPERFAMILY SSF57716 98 136 2.42E-8 T 14-10-2018 TSH58p_28605 ef25fef38ba0ed03f0f3e0f93b05e4d0 379 ProSitePatterns PS00534 Ferrochelatase signature. 227 245 - T 14-10-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 TSH58p_28605 ef25fef38ba0ed03f0f3e0f93b05e4d0 379 Gene3D G3DSA:3.40.50.1400 36 358 4.0E-97 T 14-10-2018 TSH58p_28605 ef25fef38ba0ed03f0f3e0f93b05e4d0 379 TIGRFAM TIGR00109 hemH: ferrochelatase 34 358 2.0E-86 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 TSH58p_28605 ef25fef38ba0ed03f0f3e0f93b05e4d0 379 SUPERFAMILY SSF53800 34 363 4.74E-105 T 14-10-2018 TSH58p_28605 ef25fef38ba0ed03f0f3e0f93b05e4d0 379 Hamap MF_00323 Ferrochelatase [hemH]. 34 358 37.391 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 TSH58p_28605 ef25fef38ba0ed03f0f3e0f93b05e4d0 379 Pfam PF00762 Ferrochelatase 36 357 3.6E-111 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 TSH58p_28605 ef25fef38ba0ed03f0f3e0f93b05e4d0 379 Gene3D G3DSA:3.40.50.1400 200 339 4.0E-97 T 14-10-2018 TSH58p_29825 a8bf92819cdc0e34fee60a4048d6a40e 801 Pfam PF03968 OstA-like protein 98 143 5.4E-5 T 14-10-2018 IPR005653 Organic solvent tolerance-like, N-terminal TSH58p_29825 a8bf92819cdc0e34fee60a4048d6a40e 801 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 34 783 15.795 T 14-10-2018 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 TSH58p_29825 a8bf92819cdc0e34fee60a4048d6a40e 801 Gene3D G3DSA:2.60.450.10 86 154 8.4E-6 T 14-10-2018 TSH58p_29825 a8bf92819cdc0e34fee60a4048d6a40e 801 Pfam PF04453 Organic solvent tolerance protein 350 719 2.2E-50 T 14-10-2018 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 TSH58p_02880 c0571f00e600c5386084c044f2a93ca8 246 Pfam PF00196 Bacterial regulatory proteins, luxR family 177 231 1.1E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_02880 c0571f00e600c5386084c044f2a93ca8 246 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 191 3.3E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_02880 c0571f00e600c5386084c044f2a93ca8 246 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 207 3.3E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_02880 c0571f00e600c5386084c044f2a93ca8 246 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 207 219 3.3E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_02880 c0571f00e600c5386084c044f2a93ca8 246 SUPERFAMILY SSF52172 13 136 9.66E-8 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_02880 c0571f00e600c5386084c044f2a93ca8 246 SMART SM00421 174 231 3.0E-21 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_02880 c0571f00e600c5386084c044f2a93ca8 246 Gene3D G3DSA:3.40.50.2300 13 143 7.7E-7 T 14-10-2018 TSH58p_02880 c0571f00e600c5386084c044f2a93ca8 246 Gene3D G3DSA:1.10.10.10 175 241 3.1E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_02880 c0571f00e600c5386084c044f2a93ca8 246 SUPERFAMILY SSF46894 169 233 4.08E-18 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_19655 ef217acc7478bb0c20a3a8190d6f8b7b 125 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 123 3.1E-46 T 14-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 TSH58p_19655 ef217acc7478bb0c20a3a8190d6f8b7b 125 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 101 119 - T 14-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 TSH58p_19655 ef217acc7478bb0c20a3a8190d6f8b7b 125 Pfam PF01042 Endoribonuclease L-PSP 8 124 6.9E-37 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 TSH58p_19655 ef217acc7478bb0c20a3a8190d6f8b7b 125 SUPERFAMILY SSF55298 4 125 5.34E-41 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TSH58p_19655 ef217acc7478bb0c20a3a8190d6f8b7b 125 Gene3D G3DSA:3.30.1330.40 1 125 3.1E-47 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TSH58p_19810 67db98bdf9549e1f4d77b8f535526d14 497 PRINTS PR01874 DNA repair protein radA signature 399 427 1.0E-11 T 14-10-2018 TSH58p_19810 67db98bdf9549e1f4d77b8f535526d14 497 PRINTS PR01874 DNA repair protein radA signature 258 286 1.0E-11 T 14-10-2018 TSH58p_19810 67db98bdf9549e1f4d77b8f535526d14 497 PRINTS PR01874 DNA repair protein radA signature 300 317 1.0E-11 T 14-10-2018 TSH58p_19810 67db98bdf9549e1f4d77b8f535526d14 497 PIRSF PIRSF039117 1 493 6.4E-117 T 14-10-2018 IPR030665 Circadian clock protein kinase KaiC KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 TSH58p_19810 67db98bdf9549e1f4d77b8f535526d14 497 Gene3D G3DSA:3.40.50.300 241 484 3.6E-49 T 14-10-2018 TSH58p_19810 67db98bdf9549e1f4d77b8f535526d14 497 Gene3D G3DSA:3.40.50.300 1 239 2.4E-50 T 14-10-2018 TSH58p_19810 67db98bdf9549e1f4d77b8f535526d14 497 Pfam PF06745 KaiC 12 234 1.4E-40 T 14-10-2018 IPR014774 KaiC-like domain TSH58p_19810 67db98bdf9549e1f4d77b8f535526d14 497 Pfam PF06745 KaiC 252 468 7.7E-27 T 14-10-2018 IPR014774 KaiC-like domain TSH58p_19810 67db98bdf9549e1f4d77b8f535526d14 497 SUPERFAMILY SSF52540 6 243 3.28E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_19810 67db98bdf9549e1f4d77b8f535526d14 497 SMART SM00382 27 211 0.55 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_19810 67db98bdf9549e1f4d77b8f535526d14 497 SMART SM00382 266 430 0.0014 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_19810 67db98bdf9549e1f4d77b8f535526d14 497 SUPERFAMILY SSF52540 247 481 1.03E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_20570 f6c3f3f3ec8686bea0b1c6a1572b2efd 513 ProSitePatterns PS00211 ABC transporters family signature. 404 418 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_20570 f6c3f3f3ec8686bea0b1c6a1572b2efd 513 Gene3D G3DSA:3.40.50.300 250 494 2.9E-37 T 14-10-2018 TSH58p_20570 f6c3f3f3ec8686bea0b1c6a1572b2efd 513 Gene3D G3DSA:3.40.50.300 2 241 7.2E-58 T 14-10-2018 TSH58p_20570 f6c3f3f3ec8686bea0b1c6a1572b2efd 513 Pfam PF00005 ABC transporter 24 172 8.9E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_20570 f6c3f3f3ec8686bea0b1c6a1572b2efd 513 SMART SM00382 32 219 1.6E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_20570 f6c3f3f3ec8686bea0b1c6a1572b2efd 513 SMART SM00382 284 491 2.9 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_20570 f6c3f3f3ec8686bea0b1c6a1572b2efd 513 SUPERFAMILY SSF52540 257 488 6.45E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_20570 f6c3f3f3ec8686bea0b1c6a1572b2efd 513 Pfam PF00005 ABC transporter 275 431 1.1E-13 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_20570 f6c3f3f3ec8686bea0b1c6a1572b2efd 513 SUPERFAMILY SSF52540 7 229 4.17E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_20570 f6c3f3f3ec8686bea0b1c6a1572b2efd 513 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_15400 9a30372d50cc26a80b6175b227703a96 256 SMART SM00858 125 187 5.3E-8 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 TSH58p_15400 9a30372d50cc26a80b6175b227703a96 256 TIGRFAM TIGR03170 flgA_cterm: flagella basal body P-ring formation protein FlgA 115 248 8.4E-34 T 14-10-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal TSH58p_15400 9a30372d50cc26a80b6175b227703a96 256 Pfam PF13144 Chaperone for flagella basal body P-ring formation 50 248 2.1E-37 T 14-10-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal TSH58p_15400 9a30372d50cc26a80b6175b227703a96 256 Gene3D G3DSA:2.30.30.760 192 251 2.2E-10 T 14-10-2018 TSH58p_14880 da493acdb99fa5a5e61a462b871199f6 918 Pfam PF08239 Bacterial SH3 domain 595 636 1.2E-6 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type TSH58p_14880 da493acdb99fa5a5e61a462b871199f6 918 Pfam PF00656 Caspase domain 41 268 3.0E-27 T 14-10-2018 TSH58p_14880 da493acdb99fa5a5e61a462b871199f6 918 SUPERFAMILY SSF52129 33 270 4.64E-45 T 14-10-2018 IPR029030 Caspase-like domain superfamily TSH58p_14880 da493acdb99fa5a5e61a462b871199f6 918 Gene3D G3DSA:3.90.1580.10 677 918 1.7E-57 T 14-10-2018 TSH58p_14880 da493acdb99fa5a5e61a462b871199f6 918 SMART SM00115 32 270 0.0081 T 14-10-2018 IPR015917 Peptidase C14A, caspase catalytic domain GO:0008234 TSH58p_14880 da493acdb99fa5a5e61a462b871199f6 918 SUPERFAMILY SSF56436 688 917 2.59E-62 T 14-10-2018 IPR016187 C-type lectin fold TSH58p_14880 da493acdb99fa5a5e61a462b871199f6 918 Gene3D G3DSA:3.40.50.1460 31 272 3.7E-53 T 14-10-2018 TSH58p_14880 da493acdb99fa5a5e61a462b871199f6 918 Gene3D G3DSA:2.30.30.40 580 650 4.0E-5 T 14-10-2018 TSH58p_14880 da493acdb99fa5a5e61a462b871199f6 918 Pfam PF03781 Sulfatase-modifying factor enzyme 1 688 915 2.8E-55 T 14-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 TSH58p_05080 f4ae3dad31dd74920f96fd2d9030488d 577 Gene3D G3DSA:3.30.1490.20 54 285 2.6E-90 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSH58p_05080 f4ae3dad31dd74920f96fd2d9030488d 577 Gene3D G3DSA:3.30.470.20 286 387 6.9E-34 T 14-10-2018 TSH58p_05080 f4ae3dad31dd74920f96fd2d9030488d 577 Pfam PF00391 PEP-utilising enzyme, mobile domain 468 547 9.1E-21 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TSH58p_05080 f4ae3dad31dd74920f96fd2d9030488d 577 Gene3D G3DSA:1.10.189.10 391 573 2.5E-57 T 14-10-2018 TSH58p_05080 f4ae3dad31dd74920f96fd2d9030488d 577 SUPERFAMILY SSF52009 430 556 1.83E-31 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 TSH58p_05080 f4ae3dad31dd74920f96fd2d9030488d 577 Gene3D G3DSA:1.20.80.30 153 240 2.6E-90 T 14-10-2018 TSH58p_05080 f4ae3dad31dd74920f96fd2d9030488d 577 SUPERFAMILY SSF56059 41 417 4.59E-122 T 14-10-2018 TSH58p_05080 f4ae3dad31dd74920f96fd2d9030488d 577 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 104 330 2.1E-29 T 14-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 TSH58p_05080 f4ae3dad31dd74920f96fd2d9030488d 577 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 344 401 6.4E-10 T 14-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 TSH58p_05080 f4ae3dad31dd74920f96fd2d9030488d 577 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 61 92 1.2E-6 T 14-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 TSH58p_05080 f4ae3dad31dd74920f96fd2d9030488d 577 Gene3D G3DSA:3.50.30.10 429 553 2.5E-57 T 14-10-2018 TSH58p_11685 d83a7d92af506327d52f5bf4b83ea2ab 421 SUPERFAMILY SSF161098 195 414 5.23E-36 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_11685 d83a7d92af506327d52f5bf4b83ea2ab 421 Pfam PF11812 Domain of unknown function (DUF3333) 17 155 6.2E-51 T 14-10-2018 IPR024573 Domain of unknown function DUF3333 TSH58p_11685 d83a7d92af506327d52f5bf4b83ea2ab 421 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 218 417 2.2E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_11685 d83a7d92af506327d52f5bf4b83ea2ab 421 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 179 418 1.5E-65 T 14-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 TSH58p_11685 d83a7d92af506327d52f5bf4b83ea2ab 421 Gene3D G3DSA:1.10.3720.10 196 420 4.2E-34 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_28640 16508d43925d1526e07084babb5d1e85 326 SUPERFAMILY SSF50156 202 307 2.5E-12 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 TSH58p_28640 16508d43925d1526e07084babb5d1e85 326 SUPERFAMILY SSF50494 22 226 1.99E-27 T 14-10-2018 IPR009003 Peptidase S1, PA clan TSH58p_28640 16508d43925d1526e07084babb5d1e85 326 PRINTS PR00834 HtrA/DegQ protease family signature 180 197 1.8E-6 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_28640 16508d43925d1526e07084babb5d1e85 326 PRINTS PR00834 HtrA/DegQ protease family signature 63 75 1.8E-6 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_28640 16508d43925d1526e07084babb5d1e85 326 PRINTS PR00834 HtrA/DegQ protease family signature 261 273 1.8E-6 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_28640 16508d43925d1526e07084babb5d1e85 326 PRINTS PR00834 HtrA/DegQ protease family signature 84 104 1.8E-6 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_28640 16508d43925d1526e07084babb5d1e85 326 Pfam PF13180 PDZ domain 232 306 5.0E-9 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_28640 16508d43925d1526e07084babb5d1e85 326 Pfam PF13365 Trypsin-like peptidase domain 54 187 3.9E-12 T 14-10-2018 TSH58p_28640 16508d43925d1526e07084babb5d1e85 326 Gene3D G3DSA:2.30.42.10 230 322 2.0E-11 T 14-10-2018 TSH58p_28640 16508d43925d1526e07084babb5d1e85 326 Gene3D G3DSA:2.40.10.120 16 226 1.8E-20 T 14-10-2018 TSH58p_08465 7fc3f68625386f0af4b73e1a82eecbf6 341 SUPERFAMILY SSF51430 1 311 4.85E-102 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TSH58p_08465 7fc3f68625386f0af4b73e1a82eecbf6 341 PRINTS PR00069 Aldo-keto reductase signature 103 121 4.5E-8 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TSH58p_08465 7fc3f68625386f0af4b73e1a82eecbf6 341 PRINTS PR00069 Aldo-keto reductase signature 134 151 4.5E-8 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TSH58p_08465 7fc3f68625386f0af4b73e1a82eecbf6 341 PRINTS PR00069 Aldo-keto reductase signature 39 63 4.5E-8 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TSH58p_08465 7fc3f68625386f0af4b73e1a82eecbf6 341 Gene3D G3DSA:3.20.20.100 1 323 9.5E-116 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TSH58p_08465 7fc3f68625386f0af4b73e1a82eecbf6 341 Pfam PF00248 Aldo/keto reductase family 15 310 3.2E-72 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain TSH58p_10345 16b777fb0c5a28b916b00181c8929935 262 SUPERFAMILY SSF56219 26 262 6.41E-40 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TSH58p_10345 16b777fb0c5a28b916b00181c8929935 262 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 37 252 1.3E-16 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase TSH58p_10345 16b777fb0c5a28b916b00181c8929935 262 Gene3D G3DSA:3.60.10.10 33 262 5.7E-49 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TSH58p_28945 0aa0fc9f1586ee42024a088a71516f48 493 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 16 482 6.1E-171 T 14-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_28945 0aa0fc9f1586ee42024a088a71516f48 493 ProSitePatterns PS00571 Amidases signature. 159 190 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 TSH58p_28945 0aa0fc9f1586ee42024a088a71516f48 493 Pfam PF01425 Amidase 25 473 2.1E-145 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_28945 0aa0fc9f1586ee42024a088a71516f48 493 SUPERFAMILY SSF75304 4 491 2.49E-155 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_28945 0aa0fc9f1586ee42024a088a71516f48 493 Gene3D G3DSA:3.90.1300.10 4 492 1.0E-186 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_28945 0aa0fc9f1586ee42024a088a71516f48 493 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 12 484 91.531 T 14-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_25080 20ae857b75b04259ae9086cadfad8e42 938 SUPERFAMILY SSF53448 155 364 5.44E-29 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_25080 20ae857b75b04259ae9086cadfad8e42 938 Pfam PF00535 Glycosyl transferase family 2 155 296 9.2E-22 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_25080 20ae857b75b04259ae9086cadfad8e42 938 Gene3D G3DSA:1.25.40.10 6 131 3.7E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25080 20ae857b75b04259ae9086cadfad8e42 938 SMART SM00028 25 58 180.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25080 20ae857b75b04259ae9086cadfad8e42 938 SMART SM00028 582 615 170.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25080 20ae857b75b04259ae9086cadfad8e42 938 SMART SM00028 446 479 200.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25080 20ae857b75b04259ae9086cadfad8e42 938 SMART SM00028 514 547 1.7 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25080 20ae857b75b04259ae9086cadfad8e42 938 SMART SM00028 548 581 120.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25080 20ae857b75b04259ae9086cadfad8e42 938 SMART SM00028 616 649 20.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25080 20ae857b75b04259ae9086cadfad8e42 938 SMART SM00028 480 513 120.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25080 20ae857b75b04259ae9086cadfad8e42 938 SUPERFAMILY SSF48452 17 131 6.21E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25080 20ae857b75b04259ae9086cadfad8e42 938 Gene3D G3DSA:3.90.550.10 152 370 5.4E-28 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_25080 20ae857b75b04259ae9086cadfad8e42 938 SUPERFAMILY SSF48452 451 655 8.13E-25 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25080 20ae857b75b04259ae9086cadfad8e42 938 Gene3D G3DSA:1.25.40.10 432 661 5.1E-35 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25080 20ae857b75b04259ae9086cadfad8e42 938 Pfam PF13432 Tetratricopeptide repeat 589 646 0.0088 T 14-10-2018 TSH58p_25080 20ae857b75b04259ae9086cadfad8e42 938 Pfam PF13432 Tetratricopeptide repeat 452 507 2.5E-6 T 14-10-2018 TSH58p_09680 f3916b9b61934882620903046fd4627c 778 Gene3D G3DSA:3.30.450.20 229 299 1.7E-17 T 14-10-2018 TSH58p_09680 f3916b9b61934882620903046fd4627c 778 SMART SM00091 362 429 0.059 T 14-10-2018 IPR000014 PAS domain TSH58p_09680 f3916b9b61934882620903046fd4627c 778 SMART SM00091 233 301 0.0045 T 14-10-2018 IPR000014 PAS domain TSH58p_09680 f3916b9b61934882620903046fd4627c 778 Gene3D G3DSA:2.10.70.100 307 352 2.8E-11 T 14-10-2018 TSH58p_09680 f3916b9b61934882620903046fd4627c 778 Gene3D G3DSA:1.10.287.130 491 591 3.1E-18 T 14-10-2018 TSH58p_09680 f3916b9b61934882620903046fd4627c 778 Gene3D G3DSA:3.30.565.10 596 767 1.4E-32 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_09680 f3916b9b61934882620903046fd4627c 778 SMART SM00086 442 477 440.0 T 14-10-2018 IPR001610 PAC motif TSH58p_09680 f3916b9b61934882620903046fd4627c 778 SMART SM00086 308 350 2.6E-7 T 14-10-2018 IPR001610 PAC motif TSH58p_09680 f3916b9b61934882620903046fd4627c 778 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 641 760 3.2E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_09680 f3916b9b61934882620903046fd4627c 778 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 229 357 5.0E-13 T 14-10-2018 IPR000014 PAS domain TSH58p_09680 f3916b9b61934882620903046fd4627c 778 Pfam PF12860 PAS fold 368 481 9.2E-27 T 14-10-2018 TSH58p_09680 f3916b9b61934882620903046fd4627c 778 SMART SM00304 174 226 1.7E-4 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_09680 f3916b9b61934882620903046fd4627c 778 SUPERFAMILY SSF55785 346 463 7.5E-13 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_09680 f3916b9b61934882620903046fd4627c 778 SUPERFAMILY SSF55874 587 761 5.89E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_09680 f3916b9b61934882620903046fd4627c 778 SUPERFAMILY SSF55785 243 353 1.05E-19 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_09680 f3916b9b61934882620903046fd4627c 778 Pfam PF08447 PAS fold 257 344 6.8E-19 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 TSH58p_09680 f3916b9b61934882620903046fd4627c 778 Gene3D G3DSA:3.30.450.20 353 483 2.5E-11 T 14-10-2018 TSH58p_09680 f3916b9b61934882620903046fd4627c 778 PRINTS PR00344 Bacterial sensor protein C-terminal signature 698 708 2.8E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_09680 f3916b9b61934882620903046fd4627c 778 PRINTS PR00344 Bacterial sensor protein C-terminal signature 680 694 2.8E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_09680 f3916b9b61934882620903046fd4627c 778 PRINTS PR00344 Bacterial sensor protein C-terminal signature 711 729 2.8E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_09680 f3916b9b61934882620903046fd4627c 778 SMART SM00387 639 762 2.5E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_14090 520537cc3332f3410c439f39f40c96c3 288 Gene3D G3DSA:3.40.630.40 5 282 1.1E-102 T 14-10-2018 TSH58p_14090 520537cc3332f3410c439f39f40c96c3 288 SUPERFAMILY SSF53187 14 277 1.82E-83 T 14-10-2018 TSH58p_14090 520537cc3332f3410c439f39f40c96c3 288 Pfam PF05013 N-formylglutamate amidohydrolase 20 249 1.4E-66 T 14-10-2018 IPR007709 N-formylglutamate amidohydrolase TSH58p_27580 f6f7add701ef7ec45ac1cc93d17fc60b 504 SUPERFAMILY SSF46689 333 486 8.24E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_27580 f6f7add701ef7ec45ac1cc93d17fc60b 504 Gene3D G3DSA:1.10.8.60 291 368 2.5E-23 T 14-10-2018 TSH58p_27580 f6f7add701ef7ec45ac1cc93d17fc60b 504 SMART SM00382 140 284 2.0E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_27580 f6f7add701ef7ec45ac1cc93d17fc60b 504 Gene3D G3DSA:3.40.50.2300 1 112 2.2E-7 T 14-10-2018 TSH58p_27580 f6f7add701ef7ec45ac1cc93d17fc60b 504 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 452 469 2.7E-7 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_27580 f6f7add701ef7ec45ac1cc93d17fc60b 504 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 469 489 2.7E-7 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_27580 f6f7add701ef7ec45ac1cc93d17fc60b 504 SUPERFAMILY SSF52172 21 164 3.08E-15 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_27580 f6f7add701ef7ec45ac1cc93d17fc60b 504 Pfam PF00158 Sigma-54 interaction domain 120 286 2.4E-69 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 TSH58p_27580 f6f7add701ef7ec45ac1cc93d17fc60b 504 Gene3D G3DSA:3.40.50.300 113 290 2.4E-68 T 14-10-2018 TSH58p_27580 f6f7add701ef7ec45ac1cc93d17fc60b 504 SUPERFAMILY SSF52540 120 361 6.17E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_27580 f6f7add701ef7ec45ac1cc93d17fc60b 504 Pfam PF00072 Response regulator receiver domain 19 108 6.4E-5 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_27580 f6f7add701ef7ec45ac1cc93d17fc60b 504 Pfam PF02954 Bacterial regulatory protein, Fis family 446 486 3.7E-14 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_27580 f6f7add701ef7ec45ac1cc93d17fc60b 504 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 144 157 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 TSH58p_27580 f6f7add701ef7ec45ac1cc93d17fc60b 504 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 206 221 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 TSH58p_27580 f6f7add701ef7ec45ac1cc93d17fc60b 504 Gene3D G3DSA:1.10.10.60 428 487 4.2E-14 T 14-10-2018 TSH58p_24395 180f4b1dae9d66e131be7bb08669b3fd 643 SUPERFAMILY SSF48239 51 319 2.43E-72 T 14-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TSH58p_24395 180f4b1dae9d66e131be7bb08669b3fd 643 SUPERFAMILY SSF48239 22 639 1.8E-103 T 14-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TSH58p_24395 180f4b1dae9d66e131be7bb08669b3fd 643 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 323 639 4.8E-137 T 14-10-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 TSH58p_24395 180f4b1dae9d66e131be7bb08669b3fd 643 Gene3D G3DSA:1.50.10.20 47 322 5.3E-225 T 14-10-2018 TSH58p_24395 180f4b1dae9d66e131be7bb08669b3fd 643 Gene3D G3DSA:1.50.10.20 29 638 5.3E-225 T 14-10-2018 TSH58p_24395 180f4b1dae9d66e131be7bb08669b3fd 643 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 26 639 9.1E-180 T 14-10-2018 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 TSH58p_24395 180f4b1dae9d66e131be7bb08669b3fd 643 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 26 313 1.3E-117 T 14-10-2018 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 TSH58p_24395 180f4b1dae9d66e131be7bb08669b3fd 643 TIGRFAM TIGR01507 hopene_cyclase: squalene-hopene cyclase 16 642 2.3E-233 T 14-10-2018 IPR006400 Squalene hopene cyclase GO:0016866|GO:0019746 KEGG: 00909+4.2.1.129+5.4.99.17|MetaCyc: PWY-6098|MetaCyc: PWY-7072 TSH58p_20515 27a371214a673b6702bf4269760881d9 917 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 192 203 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_20515 27a371214a673b6702bf4269760881d9 917 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 664 681 - T 14-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 TSH58p_20515 27a371214a673b6702bf4269760881d9 917 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 3 81 3.0E-16 T 14-10-2018 TSH58p_20515 27a371214a673b6702bf4269760881d9 917 PIRSF PIRSF036643 1 917 0.0 T 14-10-2018 TSH58p_20515 27a371214a673b6702bf4269760881d9 917 Pfam PF01568 Molydopterin dinucleotide binding domain 805 908 4.2E-28 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TSH58p_20515 27a371214a673b6702bf4269760881d9 917 SUPERFAMILY SSF50692 770 916 3.84E-43 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TSH58p_20515 27a371214a673b6702bf4269760881d9 917 SUPERFAMILY SSF54292 5 127 4.21E-26 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TSH58p_20515 27a371214a673b6702bf4269760881d9 917 Gene3D G3DSA:3.10.20.740 6 107 4.9E-20 T 14-10-2018 TSH58p_20515 27a371214a673b6702bf4269760881d9 917 SUPERFAMILY SSF53706 224 754 7.72E-197 T 14-10-2018 TSH58p_20515 27a371214a673b6702bf4269760881d9 917 Pfam PF13187 4Fe-4S dicluster domain 148 206 1.2E-6 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_20515 27a371214a673b6702bf4269760881d9 917 Gene3D G3DSA:3.40.228.10 374 572 1.5E-176 T 14-10-2018 TSH58p_20515 27a371214a673b6702bf4269760881d9 917 Gene3D G3DSA:2.20.25.90 226 278 1.7E-21 T 14-10-2018 TSH58p_20515 27a371214a673b6702bf4269760881d9 917 SUPERFAMILY SSF54862 135 208 1.51E-14 T 14-10-2018 TSH58p_20515 27a371214a673b6702bf4269760881d9 917 SMART SM00926 225 278 1.1E-18 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_20515 27a371214a673b6702bf4269760881d9 917 Pfam PF00384 Molybdopterin oxidoreductase 281 717 2.1E-84 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_20515 27a371214a673b6702bf4269760881d9 917 Gene3D G3DSA:3.30.70.20 128 210 3.1E-20 T 14-10-2018 TSH58p_20515 27a371214a673b6702bf4269760881d9 917 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 231 913 6.0E-223 T 14-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 TSH58p_20515 27a371214a673b6702bf4269760881d9 917 Gene3D G3DSA:2.40.40.20 794 915 9.8E-42 T 14-10-2018 TSH58p_20515 27a371214a673b6702bf4269760881d9 917 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 227 278 2.0E-14 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_20515 27a371214a673b6702bf4269760881d9 917 Gene3D G3DSA:3.40.50.740 307 760 1.5E-176 T 14-10-2018 TSH58p_01640 5c01ee00c923ee3a4a8648fe8e1d6a79 1031 SUPERFAMILY SSF82714 704 785 2.49E-14 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_01640 5c01ee00c923ee3a4a8648fe8e1d6a79 1031 Pfam PF00873 AcrB/AcrD/AcrF family 7 1003 1.7E-154 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_01640 5c01ee00c923ee3a4a8648fe8e1d6a79 1031 SUPERFAMILY SSF82693 43 139 1.7E-16 T 14-10-2018 TSH58p_01640 5c01ee00c923ee3a4a8648fe8e1d6a79 1031 Gene3D G3DSA:3.30.2090.10 183 274 4.2E-236 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_01640 5c01ee00c923ee3a4a8648fe8e1d6a79 1031 SUPERFAMILY SSF82693 140 326 1.8E-18 T 14-10-2018 TSH58p_01640 5c01ee00c923ee3a4a8648fe8e1d6a79 1031 SUPERFAMILY SSF82714 188 266 6.54E-8 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_01640 5c01ee00c923ee3a4a8648fe8e1d6a79 1031 PRINTS PR00702 Acriflavin resistance protein family signature 333 356 9.3E-20 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_01640 5c01ee00c923ee3a4a8648fe8e1d6a79 1031 PRINTS PR00702 Acriflavin resistance protein family signature 41 59 9.3E-20 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_01640 5c01ee00c923ee3a4a8648fe8e1d6a79 1031 PRINTS PR00702 Acriflavin resistance protein family signature 537 554 9.3E-20 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_01640 5c01ee00c923ee3a4a8648fe8e1d6a79 1031 PRINTS PR00702 Acriflavin resistance protein family signature 440 463 9.3E-20 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_01640 5c01ee00c923ee3a4a8648fe8e1d6a79 1031 PRINTS PR00702 Acriflavin resistance protein family signature 465 488 9.3E-20 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_01640 5c01ee00c923ee3a4a8648fe8e1d6a79 1031 PRINTS PR00702 Acriflavin resistance protein family signature 387 411 9.3E-20 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_01640 5c01ee00c923ee3a4a8648fe8e1d6a79 1031 PRINTS PR00702 Acriflavin resistance protein family signature 13 37 9.3E-20 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_01640 5c01ee00c923ee3a4a8648fe8e1d6a79 1031 Gene3D G3DSA:3.30.70.1320 139 327 4.2E-236 T 14-10-2018 TSH58p_01640 5c01ee00c923ee3a4a8648fe8e1d6a79 1031 Gene3D G3DSA:3.30.70.1440 653 853 4.2E-236 T 14-10-2018 TSH58p_01640 5c01ee00c923ee3a4a8648fe8e1d6a79 1031 SUPERFAMILY SSF82866 300 493 2.22E-30 T 14-10-2018 TSH58p_01640 5c01ee00c923ee3a4a8648fe8e1d6a79 1031 Gene3D G3DSA:3.30.2090.10 704 792 4.2E-236 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_01640 5c01ee00c923ee3a4a8648fe8e1d6a79 1031 Gene3D G3DSA:1.20.1640.10 500 1002 4.2E-236 T 14-10-2018 TSH58p_01640 5c01ee00c923ee3a4a8648fe8e1d6a79 1031 Gene3D G3DSA:1.20.1640.10 13 499 4.2E-236 T 14-10-2018 TSH58p_01640 5c01ee00c923ee3a4a8648fe8e1d6a79 1031 Gene3D G3DSA:3.30.70.1430 43 800 4.2E-236 T 14-10-2018 TSH58p_01640 5c01ee00c923ee3a4a8648fe8e1d6a79 1031 Gene3D G3DSA:3.30.70.1430 554 652 4.2E-236 T 14-10-2018 TSH58p_01640 5c01ee00c923ee3a4a8648fe8e1d6a79 1031 SUPERFAMILY SSF82866 786 1008 5.36E-42 T 14-10-2018 TSH58p_11780 b3ac8c989603fa52edf0da565f5f7051 247 Gene3D G3DSA:2.40.30.90 157 245 1.1E-19 T 14-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal TSH58p_11780 b3ac8c989603fa52edf0da565f5f7051 247 SUPERFAMILY SSF101852 154 235 4.45E-17 T 14-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal TSH58p_11780 b3ac8c989603fa52edf0da565f5f7051 247 PIRSF PIRSF006779 1 236 5.3E-55 T 14-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase TSH58p_11780 b3ac8c989603fa52edf0da565f5f7051 247 SUPERFAMILY SSF102522 1 141 4.58E-50 T 14-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal TSH58p_11780 b3ac8c989603fa52edf0da565f5f7051 247 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 2 231 1.3E-70 T 14-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase TSH58p_11780 b3ac8c989603fa52edf0da565f5f7051 247 Gene3D G3DSA:3.40.50.10790 1 148 6.5E-51 T 14-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 SMART SM00028 854 887 0.012 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 SMART SM00028 684 717 26.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 SMART SM00028 1417 1450 6.9E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 SMART SM00028 1349 1382 23.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 SMART SM00028 718 751 12.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 SMART SM00028 102 135 0.17 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 SMART SM00028 136 169 0.057 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 SMART SM00028 68 101 0.0017 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 SMART SM00028 1213 1246 24.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 SMART SM00028 752 785 0.97 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 SMART SM00028 1281 1314 34.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 SMART SM00028 786 819 9.4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 SMART SM00028 820 853 3.4E-5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 SMART SM00028 1383 1416 0.02 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 SMART SM00028 34 67 80.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 SMART SM00028 1315 1348 0.34 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 SMART SM00028 616 649 200.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 SMART SM00028 238 271 0.011 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 SMART SM00028 204 237 0.0035 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 SMART SM00028 170 203 0.022 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 SMART SM00028 650 683 80.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 SUPERFAMILY SSF53756 323 575 2.7E-10 T 14-10-2018 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 Gene3D G3DSA:1.25.40.10 1187 1482 1.2E-47 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 Gene3D G3DSA:1.25.40.10 1 308 4.9E-63 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 SUPERFAMILY SSF48452 1213 1478 2.97E-33 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 SUPERFAMILY SSF48452 4 110 7.05E-16 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 Gene3D G3DSA:1.25.40.10 866 923 9.3E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 SUPERFAMILY SSF53756 941 1179 1.57E-9 T 14-10-2018 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 Pfam PF13414 TPR repeat 871 899 3.5E-7 T 14-10-2018 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 SUPERFAMILY SSF48452 621 913 2.11E-42 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 Gene3D G3DSA:1.25.40.10 620 721 7.7E-16 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 Pfam PF13432 Tetratricopeptide repeat 622 684 2.0E-6 T 14-10-2018 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 Pfam PF13432 Tetratricopeptide repeat 1387 1451 1.8E-7 T 14-10-2018 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 Pfam PF13432 Tetratricopeptide repeat 797 852 4.1E-6 T 14-10-2018 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 Pfam PF13432 Tetratricopeptide repeat 243 296 0.004 T 14-10-2018 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 Pfam PF13432 Tetratricopeptide repeat 117 170 2.3E-7 T 14-10-2018 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 Pfam PF13432 Tetratricopeptide repeat 44 101 3.4E-5 T 14-10-2018 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 Gene3D G3DSA:1.25.40.10 722 789 7.7E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 Gene3D G3DSA:1.25.40.10 790 865 2.7E-15 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 SUPERFAMILY SSF53756 1504 1730 4.39E-13 T 14-10-2018 TSH58p_29245 fbb1b62aeff0427aca6f8b1b9afb2e5a 1782 SUPERFAMILY SSF48452 82 300 2.95E-37 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_08720 01801490596581cf37bdfdd9b8374aa6 211 Gene3D G3DSA:1.10.1670.40 3 191 3.4E-59 T 14-10-2018 TSH58p_08720 01801490596581cf37bdfdd9b8374aa6 211 SUPERFAMILY SSF48150 24 192 2.04E-42 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TSH58p_08720 01801490596581cf37bdfdd9b8374aa6 211 Gene3D G3DSA:1.10.340.30 29 140 3.4E-59 T 14-10-2018 TSH58p_08720 01801490596581cf37bdfdd9b8374aa6 211 SMART SM00478 41 193 4.2E-18 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TSH58p_08720 01801490596581cf37bdfdd9b8374aa6 211 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 39 179 3.8E-16 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TSH58p_00105 0631c84e15babc9276dd8c99a3238db7 607 SMART SM00387 489 600 1.8E-28 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_00105 0631c84e15babc9276dd8c99a3238db7 607 SMART SM00388 378 447 2.5E-5 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_00105 0631c84e15babc9276dd8c99a3238db7 607 Pfam PF00512 His Kinase A (phospho-acceptor) domain 380 443 1.4E-6 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_00105 0631c84e15babc9276dd8c99a3238db7 607 SUPERFAMILY SSF47384 375 442 1.96E-7 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_00105 0631c84e15babc9276dd8c99a3238db7 607 Pfam PF05231 MASE1 81 357 1.3E-20 T 14-10-2018 IPR007895 MASE1 TSH58p_00105 0631c84e15babc9276dd8c99a3238db7 607 Gene3D G3DSA:1.10.287.130 354 442 3.4E-16 T 14-10-2018 TSH58p_00105 0631c84e15babc9276dd8c99a3238db7 607 PRINTS PR00344 Bacterial sensor protein C-terminal signature 560 578 8.0E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_00105 0631c84e15babc9276dd8c99a3238db7 607 PRINTS PR00344 Bacterial sensor protein C-terminal signature 531 545 8.0E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_00105 0631c84e15babc9276dd8c99a3238db7 607 PRINTS PR00344 Bacterial sensor protein C-terminal signature 584 597 8.0E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_00105 0631c84e15babc9276dd8c99a3238db7 607 PRINTS PR00344 Bacterial sensor protein C-terminal signature 549 559 8.0E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_00105 0631c84e15babc9276dd8c99a3238db7 607 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 490 598 9.2E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_00105 0631c84e15babc9276dd8c99a3238db7 607 Gene3D G3DSA:3.30.565.10 452 603 7.6E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_00105 0631c84e15babc9276dd8c99a3238db7 607 SUPERFAMILY SSF55874 439 600 3.93E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_28165 a584e74b258d3a11bf0f99dae42c797b 1879 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 543 604 2.0E-7 T 14-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 TSH58p_28165 a584e74b258d3a11bf0f99dae42c797b 1879 Gene3D G3DSA:3.20.20.80 1314 1845 2.0E-134 T 14-10-2018 TSH58p_28165 a584e74b258d3a11bf0f99dae42c797b 1879 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 554 1105 1.4E-219 T 14-10-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|MetaCyc: PWY-2661 TSH58p_28165 a584e74b258d3a11bf0f99dae42c797b 1879 SMART SM00642 653 1000 2.9E-12 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSH58p_28165 a584e74b258d3a11bf0f99dae42c797b 1879 Pfam PF00128 Alpha amylase, catalytic domain 665 752 1.9E-14 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSH58p_28165 a584e74b258d3a11bf0f99dae42c797b 1879 SUPERFAMILY SSF51445 1315 1845 1.17E-145 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_28165 a584e74b258d3a11bf0f99dae42c797b 1879 TIGRFAM TIGR02457 TreS_Cterm: putative maltokinase 18 506 1.1E-120 T 14-10-2018 IPR012811 Trehalose synthase/probable maltokinase, C-terminal domain TSH58p_28165 a584e74b258d3a11bf0f99dae42c797b 1879 Pfam PF02446 4-alpha-glucanotransferase 1321 1835 2.3E-123 T 14-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 TSH58p_28165 a584e74b258d3a11bf0f99dae42c797b 1879 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 1293 1840 6.7E-137 T 14-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 TSH58p_28165 a584e74b258d3a11bf0f99dae42c797b 1879 SUPERFAMILY SSF51445 628 1058 5.38E-110 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_28165 a584e74b258d3a11bf0f99dae42c797b 1879 Gene3D G3DSA:3.90.1200.10 233 517 6.6E-63 T 14-10-2018 TSH58p_28165 a584e74b258d3a11bf0f99dae42c797b 1879 SUPERFAMILY SSF81296 539 631 1.6E-19 T 14-10-2018 IPR014756 Immunoglobulin E-set TSH58p_28165 a584e74b258d3a11bf0f99dae42c797b 1879 Gene3D G3DSA:1.10.10.760 985 1029 2.0E-184 T 14-10-2018 TSH58p_28165 a584e74b258d3a11bf0f99dae42c797b 1879 SUPERFAMILY SSF56112 173 466 1.3E-12 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily TSH58p_28165 a584e74b258d3a11bf0f99dae42c797b 1879 Gene3D G3DSA:2.60.40.10 524 630 4.0E-25 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_28165 a584e74b258d3a11bf0f99dae42c797b 1879 Gene3D G3DSA:3.20.20.80 641 1057 2.0E-184 T 14-10-2018 TSH58p_28165 a584e74b258d3a11bf0f99dae42c797b 1879 Pfam PF11941 Domain of unknown function (DUF3459) 1048 1136 5.7E-16 T 14-10-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) TSH58p_03295 e7b3065c7d37bdb9a22968e339f0f410 98 Pfam PF14542 GCN5-related N-acetyl-transferase 13 89 4.4E-29 T 14-10-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase TSH58p_03295 e7b3065c7d37bdb9a22968e339f0f410 98 SUPERFAMILY SSF55729 5 90 8.31E-29 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_03295 e7b3065c7d37bdb9a22968e339f0f410 98 Gene3D G3DSA:3.40.630.30 3 94 6.1E-31 T 14-10-2018 TSH58p_21120 b805c99252394131545b4d94c3a573e7 414 Gene3D G3DSA:3.40.50.1100 8 307 1.7E-107 T 14-10-2018 TSH58p_21120 b805c99252394131545b4d94c3a573e7 414 Gene3D G3DSA:3.30.70.260 326 399 9.0E-7 T 14-10-2018 TSH58p_21120 b805c99252394131545b4d94c3a573e7 414 SUPERFAMILY SSF53686 4 310 3.14E-86 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TSH58p_21120 b805c99252394131545b4d94c3a573e7 414 Gene3D G3DSA:3.40.50.1100 51 147 1.7E-107 T 14-10-2018 TSH58p_21120 b805c99252394131545b4d94c3a573e7 414 SUPERFAMILY SSF55021 327 393 2.63E-7 T 14-10-2018 TSH58p_21120 b805c99252394131545b4d94c3a573e7 414 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 17 302 2.9E-71 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TSH58p_21120 b805c99252394131545b4d94c3a573e7 414 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 22 396 9.3E-119 T 14-10-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 TSH58p_14105 a62a522969de9a112ebc385fe38cb92e 696 Gene3D G3DSA:3.30.70.20 282 344 1.8E-14 T 14-10-2018 TSH58p_14105 a62a522969de9a112ebc385fe38cb92e 696 Gene3D G3DSA:3.30.70.20 521 588 1.8E-10 T 14-10-2018 TSH58p_14105 a62a522969de9a112ebc385fe38cb92e 696 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 527 538 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_14105 a62a522969de9a112ebc385fe38cb92e 696 Pfam PF12838 4Fe-4S dicluster domain 289 331 5.8E-8 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_14105 a62a522969de9a112ebc385fe38cb92e 696 SUPERFAMILY SSF54862 264 627 4.49E-41 T 14-10-2018 TSH58p_14105 a62a522969de9a112ebc385fe38cb92e 696 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 317 328 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_14105 a62a522969de9a112ebc385fe38cb92e 696 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 558 569 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_00060 409d488cca81f6217f23f06d9242e2c3 258 Gene3D G3DSA:3.40.190.10 41 251 6.8E-48 T 14-10-2018 TSH58p_00060 409d488cca81f6217f23f06d9242e2c3 258 Gene3D G3DSA:3.40.190.10 117 210 6.8E-48 T 14-10-2018 TSH58p_00060 409d488cca81f6217f23f06d9242e2c3 258 SUPERFAMILY SSF53850 33 255 5.2E-47 T 14-10-2018 TSH58p_00060 409d488cca81f6217f23f06d9242e2c3 258 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 54 67 - T 14-10-2018 IPR018313 Solute-binding protein family 3, conserved site TSH58p_00060 409d488cca81f6217f23f06d9242e2c3 258 SMART SM00062 32 256 2.7E-40 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_00060 409d488cca81f6217f23f06d9242e2c3 258 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 253 6.2E-45 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_11065 873519d0743a09a3bf61e8fcefb51ba6 202 Pfam PF02545 Maf-like protein 8 195 6.1E-37 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 TSH58p_11065 873519d0743a09a3bf61e8fcefb51ba6 202 Hamap MF_00528 Septum formation protein Maf [maf]. 7 201 24.114 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 TSH58p_11065 873519d0743a09a3bf61e8fcefb51ba6 202 SUPERFAMILY SSF52972 6 195 2.55E-46 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TSH58p_11065 873519d0743a09a3bf61e8fcefb51ba6 202 Gene3D G3DSA:3.90.950.10 6 201 1.3E-48 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TSH58p_11065 873519d0743a09a3bf61e8fcefb51ba6 202 PIRSF PIRSF006305 4 200 8.3E-40 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 TSH58p_12420 8769ae57ecccd157ce5d8834ea6590c6 330 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 37 262 2.7E-58 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 TSH58p_12420 8769ae57ecccd157ce5d8834ea6590c6 330 Gene3D G3DSA:3.40.190.170 16 329 2.0E-122 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily TSH58p_12420 8769ae57ecccd157ce5d8834ea6590c6 330 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 23 312 9.8E-75 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 TSH58p_12420 8769ae57ecccd157ce5d8834ea6590c6 330 SUPERFAMILY SSF53850 66 244 3.75E-7 T 14-10-2018 TSH58p_12420 8769ae57ecccd157ce5d8834ea6590c6 330 PIRSF PIRSF006470 1 327 2.3E-85 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 TSH58p_23965 73be10970f48ee7fa6f1848e910bb2e5 699 Gene3D G3DSA:3.40.50.880 340 519 1.3E-30 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_23965 73be10970f48ee7fa6f1848e910bb2e5 699 SUPERFAMILY SSF52317 267 520 1.65E-54 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_18560 c5c15bdc0aa7d1d5af68102e21de08df 346 SUPERFAMILY SSF51430 15 328 9.95E-93 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TSH58p_18560 c5c15bdc0aa7d1d5af68102e21de08df 346 Gene3D G3DSA:3.20.20.100 17 343 1.2E-118 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TSH58p_18560 c5c15bdc0aa7d1d5af68102e21de08df 346 Pfam PF00248 Aldo/keto reductase family 30 328 2.3E-72 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain TSH58p_12790 3257403fc71dc496be2d9bed5fe3d6bb 299 Gene3D G3DSA:1.20.120.30 12 119 2.3E-6 T 14-10-2018 TSH58p_12790 3257403fc71dc496be2d9bed5fe3d6bb 299 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 126 284 1.6E-43 T 14-10-2018 IPR000160 GGDEF domain TSH58p_12790 3257403fc71dc496be2d9bed5fe3d6bb 299 SUPERFAMILY SSF55073 130 286 1.26E-42 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_12790 3257403fc71dc496be2d9bed5fe3d6bb 299 Pfam PF00990 Diguanylate cyclase, GGDEF domain 127 282 2.0E-38 T 14-10-2018 IPR000160 GGDEF domain TSH58p_12790 3257403fc71dc496be2d9bed5fe3d6bb 299 Gene3D G3DSA:3.30.70.270 122 287 1.0E-48 T 14-10-2018 TSH58p_12790 3257403fc71dc496be2d9bed5fe3d6bb 299 SMART SM00267 113 286 2.0E-45 T 14-10-2018 IPR000160 GGDEF domain TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 SMART SM00086 629 671 0.0055 T 14-10-2018 IPR001610 PAC motif TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 SMART SM00086 763 805 1.5E-5 T 14-10-2018 IPR001610 PAC motif TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 SUPERFAMILY SSF52172 1075 1191 2.42E-21 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 691 812 3.8E-12 T 14-10-2018 IPR000014 PAS domain TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 553 677 2.2E-14 T 14-10-2018 IPR000014 PAS domain TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 SUPERFAMILY SSF47384 810 890 3.14E-13 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 Gene3D G3DSA:3.30.450.20 433 544 8.7E-27 T 14-10-2018 TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 Gene3D G3DSA:3.30.450.20 316 426 1.8E-21 T 14-10-2018 TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 SMART SM00091 439 505 1.5E-12 T 14-10-2018 IPR000014 PAS domain TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 SMART SM00091 690 757 1.2E-7 T 14-10-2018 IPR000014 PAS domain TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 SMART SM00091 323 388 2.8E-5 T 14-10-2018 IPR000014 PAS domain TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 SMART SM00091 557 623 6.2E-8 T 14-10-2018 IPR000014 PAS domain TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 Gene3D G3DSA:3.30.565.10 892 1046 2.5E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 SUPERFAMILY SSF55785 423 514 4.06E-19 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 Pfam PF08448 PAS fold 697 805 5.7E-15 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 Pfam PF08448 PAS fold 445 546 1.8E-12 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 SMART SM00388 825 890 4.1E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 Pfam PF00072 Response regulator receiver domain 1075 1185 1.9E-11 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 SMART SM00387 934 1045 3.1E-31 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 Gene3D G3DSA:3.40.50.2300 1070 1194 1.6E-22 T 14-10-2018 TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 Gene3D G3DSA:3.30.450.20 554 669 3.1E-28 T 14-10-2018 TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 Pfam PF13188 PAS domain 324 374 0.0055 T 14-10-2018 IPR000014 PAS domain TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 Gene3D G3DSA:3.30.450.20 679 815 5.0E-25 T 14-10-2018 TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 SUPERFAMILY SSF55785 679 803 8.72E-22 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 Gene3D G3DSA:1.10.287.130 816 891 5.3E-12 T 14-10-2018 TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 SMART SM00448 1072 1186 1.5E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 SUPERFAMILY SSF55785 542 669 7.09E-25 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 Pfam PF08447 PAS fold 581 664 9.7E-16 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1005 1023 2.7E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1029 1042 2.7E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 PRINTS PR00344 Bacterial sensor protein C-terminal signature 970 984 2.7E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 PRINTS PR00344 Bacterial sensor protein C-terminal signature 988 998 2.7E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 SUPERFAMILY SSF55785 311 424 8.55E-12 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 935 1044 3.6E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 SUPERFAMILY SSF55874 879 1043 9.04E-40 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_22020 3d02215204cc47acd7fd375087461a4d 1194 Pfam PF00512 His Kinase A (phospho-acceptor) domain 825 890 2.3E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_18685 31861ad8d67f81865114ee697385f9f1 200 Pfam PF01323 DSBA-like thioredoxin domain 5 193 4.5E-40 T 14-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 TSH58p_18685 31861ad8d67f81865114ee697385f9f1 200 SUPERFAMILY SSF52833 5 196 2.38E-45 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_18685 31861ad8d67f81865114ee697385f9f1 200 PIRSF PIRSF006386 1 200 3.9E-57 T 14-10-2018 IPR014440 HCCA isomerase/glutathione S-transferase kappa Reactome: R-HSA-156590|Reactome: R-HSA-9033241 TSH58p_18685 31861ad8d67f81865114ee697385f9f1 200 Gene3D G3DSA:3.40.30.10 4 198 6.4E-62 T 14-10-2018 TSH58p_12575 4c37ed69412afecab7f225f814a29e07 562 Gene3D G3DSA:3.30.450.20 43 196 2.2E-28 T 14-10-2018 TSH58p_12575 4c37ed69412afecab7f225f814a29e07 562 Gene3D G3DSA:3.30.565.10 408 561 3.4E-28 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_12575 4c37ed69412afecab7f225f814a29e07 562 SUPERFAMILY SSF55874 412 552 2.76E-18 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_12575 4c37ed69412afecab7f225f814a29e07 562 Gene3D G3DSA:3.30.450.20 318 402 8.6E-9 T 14-10-2018 TSH58p_12575 4c37ed69412afecab7f225f814a29e07 562 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 449 552 8.3E-11 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_12575 4c37ed69412afecab7f225f814a29e07 562 SMART SM00387 446 555 1.7E-14 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_12575 4c37ed69412afecab7f225f814a29e07 562 Pfam PF02743 Cache domain 59 238 3.5E-12 T 14-10-2018 IPR033479 Double Cache domain 1 TSH58p_12575 4c37ed69412afecab7f225f814a29e07 562 Pfam PF07568 Histidine kinase 352 425 7.0E-24 T 14-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain TSH58p_12575 4c37ed69412afecab7f225f814a29e07 562 PRINTS PR00344 Bacterial sensor protein C-terminal signature 513 531 7.1E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_12575 4c37ed69412afecab7f225f814a29e07 562 PRINTS PR00344 Bacterial sensor protein C-terminal signature 539 552 7.1E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_12575 4c37ed69412afecab7f225f814a29e07 562 PRINTS PR00344 Bacterial sensor protein C-terminal signature 487 501 7.1E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_05155 9ce41502c570fa8351ce9677fc87884a 398 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 266 291 - T 14-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSH58p_05155 9ce41502c570fa8351ce9677fc87884a 398 Gene3D G3DSA:3.30.470.20 1 243 1.7E-94 T 14-10-2018 TSH58p_05155 9ce41502c570fa8351ce9677fc87884a 398 PIRSF PIRSF001554 1 397 2.4E-153 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSH58p_05155 9ce41502c570fa8351ce9677fc87884a 398 Gene3D G3DSA:3.40.50.261 249 397 5.0E-61 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSH58p_05155 9ce41502c570fa8351ce9677fc87884a 398 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 394 2.1E-162 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSH58p_05155 9ce41502c570fa8351ce9677fc87884a 398 Pfam PF08442 ATP-grasp domain 2 211 1.6E-78 T 14-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSH58p_05155 9ce41502c570fa8351ce9677fc87884a 398 SUPERFAMILY SSF52210 248 394 1.83E-56 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSH58p_05155 9ce41502c570fa8351ce9677fc87884a 398 SUPERFAMILY SSF56059 1 247 2.79E-82 T 14-10-2018 TSH58p_05155 9ce41502c570fa8351ce9677fc87884a 398 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 395 45.096 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSH58p_05155 9ce41502c570fa8351ce9677fc87884a 398 Gene3D G3DSA:3.30.1490.20 21 113 1.7E-94 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSH58p_05155 9ce41502c570fa8351ce9677fc87884a 398 Pfam PF00549 CoA-ligase 271 391 2.3E-27 T 14-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSH58p_18630 d95a90963eaed541919f00c706bbde20 224 SMART SM00448 1 112 2.5E-36 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_18630 d95a90963eaed541919f00c706bbde20 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 217 1.3E-18 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_18630 d95a90963eaed541919f00c706bbde20 224 SUPERFAMILY SSF52172 1 175 9.25E-41 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_18630 d95a90963eaed541919f00c706bbde20 224 Gene3D G3DSA:3.40.50.2300 1 121 4.5E-36 T 14-10-2018 TSH58p_18630 d95a90963eaed541919f00c706bbde20 224 Pfam PF00072 Response regulator receiver domain 3 111 1.8E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_18630 d95a90963eaed541919f00c706bbde20 224 Gene3D G3DSA:1.10.10.10 122 222 2.8E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_18630 d95a90963eaed541919f00c706bbde20 224 SMART SM00862 145 218 1.3E-20 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_14080 98201067e7a38b7b87f5b6314e351fd6 353 PIRSF PIRSF038991 7 352 1.0E-85 T 14-10-2018 IPR007820 AbrB family GO:0010468|GO:0016021 TSH58p_14080 98201067e7a38b7b87f5b6314e351fd6 353 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 10 163 5.3E-34 T 14-10-2018 IPR017516 AbrB duplication TSH58p_14080 98201067e7a38b7b87f5b6314e351fd6 353 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 189 340 6.0E-35 T 14-10-2018 IPR017516 AbrB duplication TSH58p_14080 98201067e7a38b7b87f5b6314e351fd6 353 Pfam PF05145 Transition state regulatory protein AbrB 33 343 9.1E-88 T 14-10-2018 IPR007820 AbrB family GO:0010468|GO:0016021 TSH58p_21570 e38e69323c1773967f59f9686044aa72 269 TIGRFAM TIGR00444 mazG: MazG family protein 11 262 2.0E-95 T 14-10-2018 IPR011551 NTP pyrophosphohydrolase MazG TSH58p_21570 e38e69323c1773967f59f9686044aa72 269 SUPERFAMILY SSF101386 2 105 5.56E-25 T 14-10-2018 TSH58p_21570 e38e69323c1773967f59f9686044aa72 269 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 28 101 4.3E-26 T 14-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core TSH58p_21570 e38e69323c1773967f59f9686044aa72 269 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 171 231 3.9E-8 T 14-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core TSH58p_21570 e38e69323c1773967f59f9686044aa72 269 Gene3D G3DSA:1.10.287.1080 135 266 1.2E-46 T 14-10-2018 TSH58p_21570 e38e69323c1773967f59f9686044aa72 269 SUPERFAMILY SSF101386 143 242 2.8E-24 T 14-10-2018 TSH58p_21570 e38e69323c1773967f59f9686044aa72 269 Gene3D G3DSA:1.10.287.1080 1 126 2.6E-44 T 14-10-2018 TSH58p_18200 24fd5382710ffb58714b900558975c98 358 Pfam PF01609 Transposase DDE domain 202 348 5.9E-13 T 14-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TSH58p_18200 24fd5382710ffb58714b900558975c98 358 Pfam PF05598 Transposase domain (DUF772) 53 121 4.2E-22 T 14-10-2018 IPR008490 Transposase InsH, N-terminal TSH58p_31335 24fd5382710ffb58714b900558975c98 358 Pfam PF01609 Transposase DDE domain 202 348 5.9E-13 T 14-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TSH58p_31335 24fd5382710ffb58714b900558975c98 358 Pfam PF05598 Transposase domain (DUF772) 53 121 4.2E-22 T 14-10-2018 IPR008490 Transposase InsH, N-terminal TSH58p_20350 70d359914b43ddbee2641aa19189ca90 781 SUPERFAMILY SSF82689 650 752 3.14E-16 T 14-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 TSH58p_20350 70d359914b43ddbee2641aa19189ca90 781 SUPERFAMILY SSF82861 525 583 2.48E-12 T 14-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 TSH58p_20350 70d359914b43ddbee2641aa19189ca90 781 SUPERFAMILY SSF50182 585 645 2.65E-12 T 14-10-2018 IPR010920 LSM domain superfamily TSH58p_20350 70d359914b43ddbee2641aa19189ca90 781 Gene3D G3DSA:3.30.70.100 651 740 4.6E-23 T 14-10-2018 TSH58p_20350 70d359914b43ddbee2641aa19189ca90 781 Gene3D G3DSA:2.30.30.60 601 649 7.1E-16 T 14-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily TSH58p_20350 70d359914b43ddbee2641aa19189ca90 781 Pfam PF00924 Mechanosensitive ion channel 543 742 1.9E-40 T 14-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 TSH58p_16195 cfba4f5618bc06500f90a6e75a5cf3a4 350 TIGRFAM TIGR00462 genX: EF-P lysine aminoacylase GenX 22 344 3.1E-115 T 14-10-2018 IPR004525 Elongation factor P--(R)-beta-lysine ligase GO:0004824|GO:0005524|GO:0005737|GO:0006430 TSH58p_16195 cfba4f5618bc06500f90a6e75a5cf3a4 350 Gene3D G3DSA:3.30.930.10 6 349 3.8E-96 T 14-10-2018 TSH58p_16195 cfba4f5618bc06500f90a6e75a5cf3a4 350 SUPERFAMILY SSF55681 16 347 1.12E-76 T 14-10-2018 TSH58p_16195 cfba4f5618bc06500f90a6e75a5cf3a4 350 Pfam PF00152 tRNA synthetases class II (D, K and N) 19 346 1.7E-39 T 14-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_16195 cfba4f5618bc06500f90a6e75a5cf3a4 350 PRINTS PR00982 Lysyl-tRNA synthetase signature 35 45 1.6E-7 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TSH58p_16195 cfba4f5618bc06500f90a6e75a5cf3a4 350 PRINTS PR00982 Lysyl-tRNA synthetase signature 103 120 1.6E-7 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TSH58p_16195 cfba4f5618bc06500f90a6e75a5cf3a4 350 PRINTS PR00982 Lysyl-tRNA synthetase signature 233 249 1.6E-7 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TSH58p_16460 c897e3c375970570f69784c681284f2e 596 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 7 591 32.835 T 14-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 TSH58p_16460 c897e3c375970570f69784c681284f2e 596 Gene3D G3DSA:1.10.8.60 327 400 6.4E-25 T 14-10-2018 TSH58p_16460 c897e3c375970570f69784c681284f2e 596 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 190 323 5.7E-42 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSH58p_16460 c897e3c375970570f69784c681284f2e 596 SUPERFAMILY SSF140990 407 589 4.32E-63 T 14-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 TSH58p_16460 c897e3c375970570f69784c681284f2e 596 ProSitePatterns PS00674 AAA-protein family signature. 295 313 - T 14-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TSH58p_16460 c897e3c375970570f69784c681284f2e 596 Gene3D G3DSA:3.40.50.300 140 326 5.1E-64 T 14-10-2018 TSH58p_16460 c897e3c375970570f69784c681284f2e 596 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 136 586 2.3E-179 T 14-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 TSH58p_16460 c897e3c375970570f69784c681284f2e 596 SUPERFAMILY SSF52540 151 395 6.26E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_16460 c897e3c375970570f69784c681284f2e 596 Pfam PF01434 Peptidase family M41 386 584 1.3E-67 T 14-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 TSH58p_16460 c897e3c375970570f69784c681284f2e 596 Gene3D G3DSA:1.20.58.760 401 595 4.2E-66 T 14-10-2018 TSH58p_16460 c897e3c375970570f69784c681284f2e 596 SMART SM00382 186 327 1.5E-23 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_09060 b954100309cb07066355efaa5c2123ac 144 PRINTS PR00608 Class II cytochrome C signature 131 142 2.4E-7 T 14-10-2018 IPR015984 Cytochrome c prime, subgroup TSH58p_09060 b954100309cb07066355efaa5c2123ac 144 PRINTS PR00608 Class II cytochrome C signature 108 131 2.4E-7 T 14-10-2018 IPR015984 Cytochrome c prime, subgroup TSH58p_09060 b954100309cb07066355efaa5c2123ac 144 Pfam PF01322 Cytochrome C' 26 142 1.3E-30 T 14-10-2018 IPR002321 Cytochrome c, class II GO:0005506|GO:0009055|GO:0020037 TSH58p_09060 b954100309cb07066355efaa5c2123ac 144 SUPERFAMILY SSF47175 25 144 3.24E-28 T 14-10-2018 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 TSH58p_09060 b954100309cb07066355efaa5c2123ac 144 PIRSF PIRSF000027 4 144 4.5E-29 T 14-10-2018 IPR012127 Cytochrome c prime GO:0005506|GO:0009055|GO:0020037|GO:0042597 TSH58p_09060 b954100309cb07066355efaa5c2123ac 144 Gene3D G3DSA:1.20.120.10 23 144 1.7E-31 T 14-10-2018 TSH58p_28280 f5a1b3e1b5ff68469f1ab8d566541b4c 764 Pfam PF00989 PAS fold 256 368 1.6E-15 T 14-10-2018 IPR013767 PAS fold GO:0006355 TSH58p_28280 f5a1b3e1b5ff68469f1ab8d566541b4c 764 SMART SM00388 405 470 6.5E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_28280 f5a1b3e1b5ff68469f1ab8d566541b4c 764 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 516 622 9.2E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_28280 f5a1b3e1b5ff68469f1ab8d566541b4c 764 SUPERFAMILY SSF47384 393 470 5.1E-12 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_28280 f5a1b3e1b5ff68469f1ab8d566541b4c 764 SMART SM00086 331 371 4.0E-4 T 14-10-2018 IPR001610 PAC motif TSH58p_28280 f5a1b3e1b5ff68469f1ab8d566541b4c 764 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 253 378 7.4E-36 T 14-10-2018 IPR000014 PAS domain TSH58p_28280 f5a1b3e1b5ff68469f1ab8d566541b4c 764 SMART SM00448 646 760 9.0E-16 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_28280 f5a1b3e1b5ff68469f1ab8d566541b4c 764 Gene3D G3DSA:3.30.565.10 475 623 3.1E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_28280 f5a1b3e1b5ff68469f1ab8d566541b4c 764 SUPERFAMILY SSF52172 648 763 4.27E-20 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_28280 f5a1b3e1b5ff68469f1ab8d566541b4c 764 SUPERFAMILY SSF55874 459 623 2.75E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_28280 f5a1b3e1b5ff68469f1ab8d566541b4c 764 SMART SM00387 514 625 9.1E-27 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_28280 f5a1b3e1b5ff68469f1ab8d566541b4c 764 Pfam PF03707 Bacterial signalling protein N terminal repeat 50 108 2.9E-16 T 14-10-2018 IPR005330 MHYT domain TSH58p_28280 f5a1b3e1b5ff68469f1ab8d566541b4c 764 Pfam PF03707 Bacterial signalling protein N terminal repeat 113 171 1.5E-18 T 14-10-2018 IPR005330 MHYT domain TSH58p_28280 f5a1b3e1b5ff68469f1ab8d566541b4c 764 Gene3D G3DSA:3.30.450.20 252 371 3.5E-39 T 14-10-2018 TSH58p_28280 f5a1b3e1b5ff68469f1ab8d566541b4c 764 Gene3D G3DSA:3.40.50.2300 646 764 2.6E-18 T 14-10-2018 TSH58p_28280 f5a1b3e1b5ff68469f1ab8d566541b4c 764 Gene3D G3DSA:1.10.287.130 372 468 1.7E-14 T 14-10-2018 TSH58p_28280 f5a1b3e1b5ff68469f1ab8d566541b4c 764 Pfam PF00512 His Kinase A (phospho-acceptor) domain 405 470 2.5E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_28280 f5a1b3e1b5ff68469f1ab8d566541b4c 764 SMART SM00091 255 321 3.8E-9 T 14-10-2018 IPR000014 PAS domain TSH58p_28280 f5a1b3e1b5ff68469f1ab8d566541b4c 764 Pfam PF00072 Response regulator receiver domain 648 760 2.2E-11 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_28280 f5a1b3e1b5ff68469f1ab8d566541b4c 764 SUPERFAMILY SSF55785 266 380 3.29E-31 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_28280 f5a1b3e1b5ff68469f1ab8d566541b4c 764 PRINTS PR00344 Bacterial sensor protein C-terminal signature 609 622 2.5E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_28280 f5a1b3e1b5ff68469f1ab8d566541b4c 764 PRINTS PR00344 Bacterial sensor protein C-terminal signature 585 603 2.5E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_28280 f5a1b3e1b5ff68469f1ab8d566541b4c 764 PRINTS PR00344 Bacterial sensor protein C-terminal signature 550 564 2.5E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_05105 59252e6a0771962dee99c6a9a68c2da7 589 SUPERFAMILY SSF52467 161 349 1.93E-48 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TSH58p_05105 59252e6a0771962dee99c6a9a68c2da7 589 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 193 327 5.5E-35 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 TSH58p_05105 59252e6a0771962dee99c6a9a68c2da7 589 Gene3D G3DSA:3.40.50.1220 192 358 3.3E-49 T 14-10-2018 TSH58p_05105 59252e6a0771962dee99c6a9a68c2da7 589 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 8 172 5.0E-52 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 TSH58p_05105 59252e6a0771962dee99c6a9a68c2da7 589 TIGRFAM TIGR01504 glyox_carbo_lig: glyoxylate carboligase 2 587 0.0 T 14-10-2018 IPR006397 Glyoxylate carboligase GO:0009028|GO:0009436 KEGG: 00630+4.1.1.47 TSH58p_05105 59252e6a0771962dee99c6a9a68c2da7 589 SUPERFAMILY SSF52518 2 185 1.04E-49 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_05105 59252e6a0771962dee99c6a9a68c2da7 589 Gene3D G3DSA:3.40.50.970 359 582 1.1E-63 T 14-10-2018 TSH58p_05105 59252e6a0771962dee99c6a9a68c2da7 589 Gene3D G3DSA:3.40.50.970 2 171 5.4E-66 T 14-10-2018 TSH58p_05105 59252e6a0771962dee99c6a9a68c2da7 589 SUPERFAMILY SSF52518 369 565 2.95E-52 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_05105 59252e6a0771962dee99c6a9a68c2da7 589 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 393 553 7.0E-34 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TSH58p_15160 b5bb49601bb69cd8bca8204b904573ff 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 7.6E-48 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15160 b5bb49601bb69cd8bca8204b904573ff 102 SUPERFAMILY SSF54999 6 102 1.44E-40 T 14-10-2018 IPR036838 Ribosomal protein S10 domain superfamily TSH58p_15160 b5bb49601bb69cd8bca8204b904573ff 102 Gene3D G3DSA:3.30.70.600 1 102 1.1E-40 T 14-10-2018 IPR036838 Ribosomal protein S10 domain superfamily TSH58p_15160 b5bb49601bb69cd8bca8204b904573ff 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 4.2E-38 T 14-10-2018 IPR027486 Ribosomal protein S10 domain TSH58p_15160 b5bb49601bb69cd8bca8204b904573ff 102 SMART SM01403 7 101 3.3E-61 T 14-10-2018 IPR027486 Ribosomal protein S10 domain TSH58p_15160 b5bb49601bb69cd8bca8204b904573ff 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 28.026 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15160 b5bb49601bb69cd8bca8204b904573ff 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 14-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15160 b5bb49601bb69cd8bca8204b904573ff 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 5.7E-19 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15160 b5bb49601bb69cd8bca8204b904573ff 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 5.7E-19 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15160 b5bb49601bb69cd8bca8204b904573ff 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 5.7E-19 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_19870 ce1abcf17091fa57ddb3391f57acd158 401 Gene3D G3DSA:3.30.750.44 54 341 7.0E-82 T 14-10-2018 TSH58p_19870 ce1abcf17091fa57ddb3391f57acd158 401 Pfam PF13180 PDZ domain 103 183 9.2E-13 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_19870 ce1abcf17091fa57ddb3391f57acd158 401 Gene3D G3DSA:3.90.226.10 191 362 7.0E-82 T 14-10-2018 TSH58p_19870 ce1abcf17091fa57ddb3391f57acd158 401 SMART SM00245 176 366 5.2E-58 T 14-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 TSH58p_19870 ce1abcf17091fa57ddb3391f57acd158 401 Gene3D G3DSA:2.30.42.10 103 190 7.0E-82 T 14-10-2018 TSH58p_19870 ce1abcf17091fa57ddb3391f57acd158 401 SUPERFAMILY SSF52096 44 370 4.14E-60 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_19870 ce1abcf17091fa57ddb3391f57acd158 401 Pfam PF03572 Peptidase family S41 201 364 5.2E-50 T 14-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 TSH58p_19870 ce1abcf17091fa57ddb3391f57acd158 401 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 65 371 4.7E-81 T 14-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 TSH58p_19870 ce1abcf17091fa57ddb3391f57acd158 401 SUPERFAMILY SSF50156 96 195 6.92E-19 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 TSH58p_19870 ce1abcf17091fa57ddb3391f57acd158 401 SMART SM00228 103 174 1.5E-14 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_21520 98aaa6a9c325d7ce6ba47b781c1c22a3 458 Gene3D G3DSA:3.30.70.1450 141 232 3.3E-17 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSH58p_21520 98aaa6a9c325d7ce6ba47b781c1c22a3 458 Gene3D G3DSA:3.30.70.1450 371 458 8.0E-25 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSH58p_21520 98aaa6a9c325d7ce6ba47b781c1c22a3 458 Pfam PF02254 TrkA-N domain 236 354 1.2E-22 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TSH58p_21520 98aaa6a9c325d7ce6ba47b781c1c22a3 458 Pfam PF02254 TrkA-N domain 3 126 1.4E-27 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TSH58p_21520 98aaa6a9c325d7ce6ba47b781c1c22a3 458 SUPERFAMILY SSF51735 234 380 3.23E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_21520 98aaa6a9c325d7ce6ba47b781c1c22a3 458 SUPERFAMILY SSF116726 365 451 8.24E-15 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSH58p_21520 98aaa6a9c325d7ce6ba47b781c1c22a3 458 Gene3D G3DSA:3.40.50.720 234 370 1.8E-34 T 14-10-2018 TSH58p_21520 98aaa6a9c325d7ce6ba47b781c1c22a3 458 Gene3D G3DSA:3.40.50.720 2 140 1.4E-44 T 14-10-2018 TSH58p_21520 98aaa6a9c325d7ce6ba47b781c1c22a3 458 Pfam PF02080 TrkA-C domain 162 227 6.4E-9 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TSH58p_21520 98aaa6a9c325d7ce6ba47b781c1c22a3 458 Pfam PF02080 TrkA-C domain 385 451 1.9E-15 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TSH58p_21520 98aaa6a9c325d7ce6ba47b781c1c22a3 458 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 3.0E-22 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TSH58p_21520 98aaa6a9c325d7ce6ba47b781c1c22a3 458 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 3.0E-22 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TSH58p_21520 98aaa6a9c325d7ce6ba47b781c1c22a3 458 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 3.0E-22 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TSH58p_21520 98aaa6a9c325d7ce6ba47b781c1c22a3 458 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 3.0E-22 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TSH58p_21520 98aaa6a9c325d7ce6ba47b781c1c22a3 458 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 3.0E-22 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TSH58p_21520 98aaa6a9c325d7ce6ba47b781c1c22a3 458 SUPERFAMILY SSF51735 2 153 1.18E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_21520 98aaa6a9c325d7ce6ba47b781c1c22a3 458 SUPERFAMILY SSF116726 136 227 3.14E-13 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSH58p_14035 99190bf7ea6f5a6fe897b5ae7e9dac2f 420 SUPERFAMILY SSF52172 38 179 2.99E-37 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_14035 99190bf7ea6f5a6fe897b5ae7e9dac2f 420 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 231 419 5.6E-36 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSH58p_14035 99190bf7ea6f5a6fe897b5ae7e9dac2f 420 Gene3D G3DSA:3.40.50.2300 41 167 3.9E-31 T 14-10-2018 TSH58p_14035 99190bf7ea6f5a6fe897b5ae7e9dac2f 420 SMART SM00331 204 419 1.2E-22 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSH58p_14035 99190bf7ea6f5a6fe897b5ae7e9dac2f 420 Pfam PF00072 Response regulator receiver domain 45 157 1.4E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_14035 99190bf7ea6f5a6fe897b5ae7e9dac2f 420 SMART SM00448 43 157 1.4E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_14035 99190bf7ea6f5a6fe897b5ae7e9dac2f 420 Gene3D G3DSA:3.60.40.10 168 420 4.1E-54 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSH58p_30960 f26af9994b0809b0a0d59bf3502b1dc2 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 246 1.2E-68 T 14-10-2018 TSH58p_30960 f26af9994b0809b0a0d59bf3502b1dc2 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.4E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30960 f26af9994b0809b0a0d59bf3502b1dc2 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.4E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30960 f26af9994b0809b0a0d59bf3502b1dc2 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.4E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30960 f26af9994b0809b0a0d59bf3502b1dc2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 7.5E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30960 f26af9994b0809b0a0d59bf3502b1dc2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 7.5E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30960 f26af9994b0809b0a0d59bf3502b1dc2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 7.5E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30960 f26af9994b0809b0a0d59bf3502b1dc2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 7.5E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30960 f26af9994b0809b0a0d59bf3502b1dc2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 7.5E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30960 f26af9994b0809b0a0d59bf3502b1dc2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 7.5E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30960 f26af9994b0809b0a0d59bf3502b1dc2 249 SUPERFAMILY SSF51735 5 248 9.25E-83 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_30960 f26af9994b0809b0a0d59bf3502b1dc2 249 Gene3D G3DSA:3.40.50.720 1 248 2.3E-81 T 14-10-2018 TSH58p_30960 f26af9994b0809b0a0d59bf3502b1dc2 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_30960 f26af9994b0809b0a0d59bf3502b1dc2 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 186 0.0067 T 14-10-2018 TSH58p_27180 4aece7f077fb7e23ca71a3b384bf4c32 236 SMART SM00100 16 137 4.2E-22 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_27180 4aece7f077fb7e23ca71a3b384bf4c32 236 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 84 101 - T 14-10-2018 IPR018488 Cyclic nucleotide-binding, conserved site TSH58p_27180 4aece7f077fb7e23ca71a3b384bf4c32 236 Pfam PF00027 Cyclic nucleotide-binding domain 36 122 1.3E-23 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_27180 4aece7f077fb7e23ca71a3b384bf4c32 236 Gene3D G3DSA:2.60.120.10 6 151 4.1E-39 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_27180 4aece7f077fb7e23ca71a3b384bf4c32 236 SUPERFAMILY SSF46785 151 231 4.59E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_27180 4aece7f077fb7e23ca71a3b384bf4c32 236 Pfam PF13545 Crp-like helix-turn-helix domain 155 227 6.7E-16 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_27180 4aece7f077fb7e23ca71a3b384bf4c32 236 SUPERFAMILY SSF51206 10 146 1.31E-33 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like TSH58p_27180 4aece7f077fb7e23ca71a3b384bf4c32 236 Gene3D G3DSA:1.10.10.10 152 234 1.1E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_27180 4aece7f077fb7e23ca71a3b384bf4c32 236 SMART SM00419 173 221 6.2E-8 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_05640 6894731cdc45b050b6948001767451ac 262 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 56 74 - T 14-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 TSH58p_05640 6894731cdc45b050b6948001767451ac 262 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 3 262 37.67 T 14-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 TSH58p_05640 6894731cdc45b050b6948001767451ac 262 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 260 3.5E-101 T 14-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 TSH58p_05640 6894731cdc45b050b6948001767451ac 262 Gene3D G3DSA:3.20.20.70 1 262 1.4E-101 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_05640 6894731cdc45b050b6948001767451ac 262 SUPERFAMILY SSF51366 12 261 1.18E-89 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TSH58p_22035 169c59d4d79aaeb0a93af06e0b0e1321 162 SUPERFAMILY SSF52833 6 155 1.11E-46 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_22035 169c59d4d79aaeb0a93af06e0b0e1321 162 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 14 152 2.6E-41 T 14-10-2018 TSH58p_22035 169c59d4d79aaeb0a93af06e0b0e1321 162 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 113 131 - T 14-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_22035 169c59d4d79aaeb0a93af06e0b0e1321 162 Gene3D G3DSA:1.10.10.1590 6 72 2.0E-12 T 14-10-2018 TSH58p_22035 169c59d4d79aaeb0a93af06e0b0e1321 162 Gene3D G3DSA:3.40.30.10 74 162 5.5E-23 T 14-10-2018 TSH58p_22035 169c59d4d79aaeb0a93af06e0b0e1321 162 PIRSF PIRSF000216 2 162 1.1E-45 T 14-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_18105 d8d6d954a7e9b9893d3c4ea2279aec9c 402 Pfam PF00534 Glycosyl transferases group 1 211 379 3.4E-15 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 TSH58p_18105 d8d6d954a7e9b9893d3c4ea2279aec9c 402 SUPERFAMILY SSF53756 37 400 1.15E-46 T 14-10-2018 TSH58p_18105 d8d6d954a7e9b9893d3c4ea2279aec9c 402 Pfam PF12000 Gkycosyl transferase family 4 group 26 191 8.1E-69 T 14-10-2018 IPR022623 Domain of unknown function DUF3495 TSH58p_18105 d8d6d954a7e9b9893d3c4ea2279aec9c 402 Gene3D G3DSA:3.40.50.2000 187 381 4.2E-35 T 14-10-2018 TSH58p_18105 d8d6d954a7e9b9893d3c4ea2279aec9c 402 Gene3D G3DSA:3.40.50.2000 15 394 4.2E-35 T 14-10-2018 TSH58p_31615 d785f84eeddeb34ed2c7a21822e6ef80 222 Gene3D G3DSA:3.40.50.2300 1 124 1.1E-31 T 14-10-2018 TSH58p_31615 d785f84eeddeb34ed2c7a21822e6ef80 222 Pfam PF00072 Response regulator receiver domain 3 111 2.3E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_31615 d785f84eeddeb34ed2c7a21822e6ef80 222 SUPERFAMILY SSF52172 2 174 5.58E-38 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_31615 d785f84eeddeb34ed2c7a21822e6ef80 222 Gene3D G3DSA:1.10.10.10 125 222 4.1E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_31615 d785f84eeddeb34ed2c7a21822e6ef80 222 SMART SM00862 146 221 7.7E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_31615 d785f84eeddeb34ed2c7a21822e6ef80 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 221 1.6E-23 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_31615 d785f84eeddeb34ed2c7a21822e6ef80 222 SMART SM00448 1 111 8.1E-38 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_21265 bcf068e0828e92409e4738c101901f4d 235 PIRSF PIRSF015000 3 219 6.9E-71 T 14-10-2018 IPR014470 Uncharacterised conserved protein UCP01500 TSH58p_21265 bcf068e0828e92409e4738c101901f4d 235 Pfam PF10028 Predicted integral membrane protein (DUF2270) 22 205 2.0E-68 T 14-10-2018 IPR014470 Uncharacterised conserved protein UCP01500 TSH58p_25310 713c181e8fbc45f0315422a5880e695f 260 Gene3D G3DSA:3.40.50.300 3 139 1.9E-7 T 14-10-2018 TSH58p_17470 a2e805cdcc8951127da450d4f77d3dae 139 Gene3D G3DSA:1.10.260.40 19 95 2.4E-15 T 14-10-2018 TSH58p_17470 a2e805cdcc8951127da450d4f77d3dae 139 SMART SM00530 34 89 1.4E-13 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_17470 a2e805cdcc8951127da450d4f77d3dae 139 Pfam PF13560 Helix-turn-helix domain 34 85 1.7E-10 T 14-10-2018 TSH58p_17470 a2e805cdcc8951127da450d4f77d3dae 139 SUPERFAMILY SSF47413 29 93 2.63E-14 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_07750 ec8032b3fa95a15f7376c69f4ea77327 433 Gene3D G3DSA:3.30.9.90 69 400 8.5E-67 T 14-10-2018 TSH58p_07750 ec8032b3fa95a15f7376c69f4ea77327 433 SUPERFAMILY SSF54373 182 285 1.22E-23 T 14-10-2018 TSH58p_07750 ec8032b3fa95a15f7376c69f4ea77327 433 SUPERFAMILY SSF51905 2 384 2.75E-47 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_07750 ec8032b3fa95a15f7376c69f4ea77327 433 Gene3D G3DSA:3.50.50.60 5 365 8.5E-67 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_07750 ec8032b3fa95a15f7376c69f4ea77327 433 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 311 9.3E-9 T 14-10-2018 TSH58p_07750 ec8032b3fa95a15f7376c69f4ea77327 433 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 9.3E-9 T 14-10-2018 TSH58p_07750 ec8032b3fa95a15f7376c69f4ea77327 433 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 154 169 9.3E-9 T 14-10-2018 TSH58p_07750 ec8032b3fa95a15f7376c69f4ea77327 433 Pfam PF01494 FAD binding domain 5 190 4.1E-7 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 TSH58p_32335 181c40bb1ccc2dabc67dde80f1edc5b3 469 SUPERFAMILY SSF51905 3 328 7.66E-35 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_32335 181c40bb1ccc2dabc67dde80f1edc5b3 469 Gene3D G3DSA:3.50.50.60 119 259 1.5E-40 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_32335 181c40bb1ccc2dabc67dde80f1edc5b3 469 Gene3D G3DSA:1.10.10.1100 367 436 4.1E-22 T 14-10-2018 TSH58p_32335 181c40bb1ccc2dabc67dde80f1edc5b3 469 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 309 2.7E-18 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSH58p_32335 181c40bb1ccc2dabc67dde80f1edc5b3 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 283 305 4.2E-15 T 14-10-2018 TSH58p_32335 181c40bb1ccc2dabc67dde80f1edc5b3 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 251 267 4.2E-15 T 14-10-2018 TSH58p_32335 181c40bb1ccc2dabc67dde80f1edc5b3 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 4.2E-15 T 14-10-2018 TSH58p_32335 181c40bb1ccc2dabc67dde80f1edc5b3 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 4.2E-15 T 14-10-2018 TSH58p_32335 181c40bb1ccc2dabc67dde80f1edc5b3 469 PIRSF PIRSF037495 1 465 8.8E-168 T 14-10-2018 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 TSH58p_32335 181c40bb1ccc2dabc67dde80f1edc5b3 469 Gene3D G3DSA:3.50.50.60 5 308 1.5E-40 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_32335 181c40bb1ccc2dabc67dde80f1edc5b3 469 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 1.5E-11 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_32335 181c40bb1ccc2dabc67dde80f1edc5b3 469 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 108 116 1.5E-11 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_32335 181c40bb1ccc2dabc67dde80f1edc5b3 469 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 293 311 1.5E-11 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_32335 181c40bb1ccc2dabc67dde80f1edc5b3 469 Pfam PF04324 BFD-like [2Fe-2S] binding domain 375 426 1.7E-11 T 14-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain TSH58p_10050 018024d2e19509c9c1335a14d3e32241 772 Pfam PF13426 PAS domain 377 473 1.3E-8 T 14-10-2018 IPR000014 PAS domain TSH58p_10050 018024d2e19509c9c1335a14d3e32241 772 Gene3D G3DSA:3.30.565.10 594 755 1.1E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_10050 018024d2e19509c9c1335a14d3e32241 772 Gene3D G3DSA:1.10.287.130 495 591 4.5E-17 T 14-10-2018 TSH58p_10050 018024d2e19509c9c1335a14d3e32241 772 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 640 753 2.5E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_10050 018024d2e19509c9c1335a14d3e32241 772 SMART SM00091 364 432 6.7E-4 T 14-10-2018 IPR000014 PAS domain TSH58p_10050 018024d2e19509c9c1335a14d3e32241 772 PRINTS PR00344 Bacterial sensor protein C-terminal signature 678 692 2.1E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_10050 018024d2e19509c9c1335a14d3e32241 772 PRINTS PR00344 Bacterial sensor protein C-terminal signature 696 706 2.1E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_10050 018024d2e19509c9c1335a14d3e32241 772 PRINTS PR00344 Bacterial sensor protein C-terminal signature 709 727 2.1E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_10050 018024d2e19509c9c1335a14d3e32241 772 PRINTS PR00344 Bacterial sensor protein C-terminal signature 738 751 2.1E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_10050 018024d2e19509c9c1335a14d3e32241 772 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 362 481 1.5E-9 T 14-10-2018 IPR000014 PAS domain TSH58p_10050 018024d2e19509c9c1335a14d3e32241 772 SMART SM00387 637 754 1.5E-25 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_10050 018024d2e19509c9c1335a14d3e32241 772 Gene3D G3DSA:3.30.450.20 361 492 3.4E-17 T 14-10-2018 TSH58p_10050 018024d2e19509c9c1335a14d3e32241 772 SUPERFAMILY SSF55785 352 473 2.27E-15 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_10050 018024d2e19509c9c1335a14d3e32241 772 SUPERFAMILY SSF55874 588 756 4.19E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_05915 be12802dbc9156e17e8bbc45e6c218ec 122 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 5 122 20.611 T 14-10-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 TSH58p_05915 be12802dbc9156e17e8bbc45e6c218ec 122 Gene3D G3DSA:1.20.58.1610 1 122 4.0E-47 T 14-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05915 be12802dbc9156e17e8bbc45e6c218ec 122 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 24 121 1.1E-41 T 14-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_07725 fda1879f5accf1de3f9efc880f332c53 381 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 14 30 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TSH58p_07725 fda1879f5accf1de3f9efc880f332c53 381 Pfam PF00682 HMGL-like 8 264 7.1E-84 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 TSH58p_07725 fda1879f5accf1de3f9efc880f332c53 381 Gene3D G3DSA:1.10.238.260 271 379 1.0E-26 T 14-10-2018 TSH58p_07725 fda1879f5accf1de3f9efc880f332c53 381 SUPERFAMILY SSF51569 3 281 2.75E-85 T 14-10-2018 TSH58p_07725 fda1879f5accf1de3f9efc880f332c53 381 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 193 206 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TSH58p_07725 fda1879f5accf1de3f9efc880f332c53 381 TIGRFAM TIGR02660 nifV_homocitr: homocitrate synthase 7 369 5.4E-161 T 14-10-2018 IPR013477 Homocitrate synthase NifV-like GO:0046912|GO:0051188 KEGG: 00300+2.3.3.14|KEGG: 00620+2.3.3.14|MetaCyc: PWY-3081|MetaCyc: PWY-7710 TSH58p_07725 fda1879f5accf1de3f9efc880f332c53 381 Gene3D G3DSA:3.20.20.70 3 269 2.1E-86 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_17640 e3707e3d932c0098cd1b511a1f795013 161 SUPERFAMILY SSF46955 7 51 3.3E-8 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily TSH58p_17640 e3707e3d932c0098cd1b511a1f795013 161 Gene3D G3DSA:1.10.1660.10 6 92 1.7E-7 T 14-10-2018 TSH58p_17640 e3707e3d932c0098cd1b511a1f795013 161 Pfam PF13411 MerR HTH family regulatory protein 8 68 9.7E-8 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_17715 e3707e3d932c0098cd1b511a1f795013 161 SUPERFAMILY SSF46955 7 51 3.3E-8 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily TSH58p_17715 e3707e3d932c0098cd1b511a1f795013 161 Gene3D G3DSA:1.10.1660.10 6 92 1.7E-7 T 14-10-2018 TSH58p_17715 e3707e3d932c0098cd1b511a1f795013 161 Pfam PF13411 MerR HTH family regulatory protein 8 68 9.7E-8 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_32535 620d74e0d4a52307030206be997e8e7e 454 ProSitePatterns PS00217 Sugar transport proteins signature 2. 121 146 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TSH58p_32535 620d74e0d4a52307030206be997e8e7e 454 ProSitePatterns PS00216 Sugar transport proteins signature 1. 79 95 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TSH58p_32535 620d74e0d4a52307030206be997e8e7e 454 SUPERFAMILY SSF103473 13 433 9.68E-73 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_32535 620d74e0d4a52307030206be997e8e7e 454 Gene3D G3DSA:1.20.1250.20 16 230 1.9E-40 T 14-10-2018 TSH58p_32535 620d74e0d4a52307030206be997e8e7e 454 Gene3D G3DSA:1.20.1250.20 259 437 5.1E-22 T 14-10-2018 TSH58p_32535 620d74e0d4a52307030206be997e8e7e 454 Pfam PF07690 Major Facilitator Superfamily 30 398 3.1E-41 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_28635 e038ba05913f0cd6d4ca63ac9c68accd 161 Gene3D G3DSA:3.10.350.10 110 158 2.2E-15 T 14-10-2018 IPR036779 LysM domain superfamily TSH58p_28635 e038ba05913f0cd6d4ca63ac9c68accd 161 Pfam PF01476 LysM domain 111 159 4.8E-13 T 14-10-2018 IPR018392 LysM domain TSH58p_28635 e038ba05913f0cd6d4ca63ac9c68accd 161 Pfam PF04972 BON domain 19 83 1.1E-10 T 14-10-2018 IPR007055 BON domain TSH58p_28635 e038ba05913f0cd6d4ca63ac9c68accd 161 SMART SM00257 110 159 3.2E-13 T 14-10-2018 IPR018392 LysM domain TSH58p_28635 e038ba05913f0cd6d4ca63ac9c68accd 161 SUPERFAMILY SSF54106 108 159 1.83E-8 T 14-10-2018 TSH58p_24775 051c43512c970acc15e48d6a19ad7620 216 Gene3D G3DSA:3.40.190.10 3 200 5.0E-62 T 14-10-2018 TSH58p_24775 051c43512c970acc15e48d6a19ad7620 216 SUPERFAMILY SSF53850 1 212 3.04E-60 T 14-10-2018 TSH58p_24775 051c43512c970acc15e48d6a19ad7620 216 Gene3D G3DSA:3.40.190.10 94 180 5.0E-62 T 14-10-2018 TSH58p_24775 051c43512c970acc15e48d6a19ad7620 216 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 1 212 46.692 T 14-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 TSH58p_24775 051c43512c970acc15e48d6a19ad7620 216 Pfam PF01634 ATP phosphoribosyltransferase 52 208 1.4E-44 T 14-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 TSH58p_24775 051c43512c970acc15e48d6a19ad7620 216 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 1 188 1.5E-52 T 14-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 TSH58p_00905 9e12da8c90de0733f3086fc4524d5fa1 615 Gene3D G3DSA:1.20.1600.10 61 480 6.2E-42 T 14-10-2018 TSH58p_00905 9e12da8c90de0733f3086fc4524d5fa1 615 SUPERFAMILY SSF56954 13 479 1.31E-53 T 14-10-2018 TSH58p_00905 9e12da8c90de0733f3086fc4524d5fa1 615 Pfam PF02321 Outer membrane efflux protein 295 473 1.2E-8 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 TSH58p_00905 9e12da8c90de0733f3086fc4524d5fa1 615 Pfam PF02321 Outer membrane efflux protein 68 267 3.8E-20 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 TSH58p_24720 573e19eedbf689109bdba57606c68537 325 Pfam PF00852 Glycosyltransferase family 10 (fucosyltransferase) C-term 179 298 1.8E-17 T 14-10-2018 IPR001503 Glycosyl transferase family 10 GO:0006486|GO:0008417|GO:0016020 TSH58p_24720 573e19eedbf689109bdba57606c68537 325 Gene3D G3DSA:3.40.50.11660 123 312 1.0E-40 T 14-10-2018 IPR038577 GT10-like superfamily TSH58p_24720 573e19eedbf689109bdba57606c68537 325 SUPERFAMILY SSF53756 60 300 5.34E-41 T 14-10-2018 TSH58p_17190 0f71d30139b160ab94dee44db101ff3b 525 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 226 234 - T 14-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 TSH58p_17190 0f71d30139b160ab94dee44db101ff3b 525 Pfam PF01068 ATP dependent DNA ligase domain 205 398 1.5E-29 T 14-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 TSH58p_17190 0f71d30139b160ab94dee44db101ff3b 525 Pfam PF04675 DNA ligase N terminus 17 158 2.1E-6 T 14-10-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 TSH58p_17190 0f71d30139b160ab94dee44db101ff3b 525 Gene3D G3DSA:3.30.470.30 202 398 3.9E-44 T 14-10-2018 TSH58p_17190 0f71d30139b160ab94dee44db101ff3b 525 SUPERFAMILY SSF50249 403 522 5.48E-32 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_17190 0f71d30139b160ab94dee44db101ff3b 525 TIGRFAM TIGR04120 DNA_lig_bact: DNA ligase, ATP-dependent, PP_1105 family 2 523 1.1E-245 T 14-10-2018 IPR026333 ATP-dependent DNA ligase, PP_1105 family TSH58p_17190 0f71d30139b160ab94dee44db101ff3b 525 Gene3D G3DSA:2.40.50.140 402 524 8.3E-31 T 14-10-2018 TSH58p_17190 0f71d30139b160ab94dee44db101ff3b 525 SUPERFAMILY SSF56091 203 398 4.56E-52 T 14-10-2018 TSH58p_17190 0f71d30139b160ab94dee44db101ff3b 525 Pfam PF04679 ATP dependent DNA ligase C terminal region 419 508 3.8E-13 T 14-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 721 793 3.8E-12 T 14-10-2018 IPR001357 BRCT domain TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 SMART SM00532 23 468 3.4E-253 T 14-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 SMART SM00292 719 795 2.7E-10 T 14-10-2018 IPR001357 BRCT domain TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 PIRSF PIRSF001604 616 795 3.6E-38 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 PIRSF PIRSF001604 16 621 2.4E-202 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 341 418 1.2E-34 T 14-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 Gene3D G3DSA:3.30.470.90 91 337 4.4E-97 T 14-10-2018 TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 SUPERFAMILY SSF47781 620 708 2.5E-13 T 14-10-2018 IPR010994 RuvA domain 2-like TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 Hamap MF_01588 DNA ligase [ligA]. 22 793 51.442 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 23 338 9.0E-119 T 14-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 SUPERFAMILY SSF50249 337 421 4.45E-27 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 SUPERFAMILY SSF52113 718 793 1.87E-18 T 14-10-2018 IPR036420 BRCT domain superfamily TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 SUPERFAMILY SSF56091 19 336 2.24E-116 T 14-10-2018 TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 31 613 1.6E-205 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 Gene3D G3DSA:1.10.150.20 621 711 6.5E-16 T 14-10-2018 TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 Gene3D G3DSA:1.10.150.20 533 614 1.5E-14 T 14-10-2018 TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 427 454 6.7E-10 T 14-10-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 137 166 - T 14-10-2018 IPR018239 NAD-dependent DNA ligase, active site TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 Gene3D G3DSA:2.40.50.140 338 410 5.8E-33 T 14-10-2018 TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 Gene3D G3DSA:2.20.70.80 411 451 2.4E-17 T 14-10-2018 TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 SMART SM00278 539 558 560.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 SMART SM00278 582 601 14.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 SMART SM00278 669 688 95.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 Gene3D G3DSA:1.10.287.610 19 90 5.8E-24 T 14-10-2018 TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 Pfam PF12826 Helix-hairpin-helix motif 627 698 2.6E-8 T 14-10-2018 TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 Pfam PF12826 Helix-hairpin-helix motif 537 607 1.1E-10 T 14-10-2018 TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 SUPERFAMILY SSF47781 423 612 2.45E-46 T 14-10-2018 IPR010994 RuvA domain 2-like TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 Gene3D G3DSA:1.10.150.20 452 531 1.3E-26 T 14-10-2018 TSH58p_14270 001c6d4dd37ffaed268be4603cf47de1 795 Gene3D G3DSA:3.40.50.10190 718 795 6.6E-26 T 14-10-2018 IPR036420 BRCT domain superfamily TSH58p_05630 58b78e6d0aaada09cef3bddbc1ff4a76 196 Gene3D G3DSA:3.40.50.880 1 191 1.2E-62 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_05630 58b78e6d0aaada09cef3bddbc1ff4a76 196 SUPERFAMILY SSF52317 1 190 3.91E-58 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_05630 58b78e6d0aaada09cef3bddbc1ff4a76 196 Pfam PF00117 Glutamine amidotransferase class-I 3 186 6.0E-56 T 14-10-2018 IPR017926 Glutamine amidotransferase TSH58p_05630 58b78e6d0aaada09cef3bddbc1ff4a76 196 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 1.9E-8 T 14-10-2018 TSH58p_05630 58b78e6d0aaada09cef3bddbc1ff4a76 196 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 75 91 1.9E-8 T 14-10-2018 TSH58p_05630 58b78e6d0aaada09cef3bddbc1ff4a76 196 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 1.4E-13 T 14-10-2018 TSH58p_05630 58b78e6d0aaada09cef3bddbc1ff4a76 196 PRINTS PR00096 Glutamine amidotransferase superfamily signature 165 178 1.4E-13 T 14-10-2018 TSH58p_05630 58b78e6d0aaada09cef3bddbc1ff4a76 196 PRINTS PR00096 Glutamine amidotransferase superfamily signature 75 86 1.4E-13 T 14-10-2018 TSH58p_05630 58b78e6d0aaada09cef3bddbc1ff4a76 196 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 187 3.5E-69 T 14-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TSH58p_05630 58b78e6d0aaada09cef3bddbc1ff4a76 196 PRINTS PR00097 Anthranilate synthase component II signature 120 132 6.8E-34 T 14-10-2018 TSH58p_05630 58b78e6d0aaada09cef3bddbc1ff4a76 196 PRINTS PR00097 Anthranilate synthase component II signature 100 108 6.8E-34 T 14-10-2018 TSH58p_05630 58b78e6d0aaada09cef3bddbc1ff4a76 196 PRINTS PR00097 Anthranilate synthase component II signature 2 16 6.8E-34 T 14-10-2018 TSH58p_05630 58b78e6d0aaada09cef3bddbc1ff4a76 196 PRINTS PR00097 Anthranilate synthase component II signature 47 56 6.8E-34 T 14-10-2018 TSH58p_05630 58b78e6d0aaada09cef3bddbc1ff4a76 196 PRINTS PR00097 Anthranilate synthase component II signature 165 178 6.8E-34 T 14-10-2018 TSH58p_05630 58b78e6d0aaada09cef3bddbc1ff4a76 196 PRINTS PR00097 Anthranilate synthase component II signature 75 86 6.8E-34 T 14-10-2018 TSH58p_12735 4aff559ffb09028b3660c205c8faa8b5 445 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 17 440 5.3E-119 T 14-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TSH58p_12735 4aff559ffb09028b3660c205c8faa8b5 445 Gene3D G3DSA:3.65.10.10 25 239 1.1E-140 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 TSH58p_12735 4aff559ffb09028b3660c205c8faa8b5 445 PIRSF PIRSF000505 1 445 2.0E-118 T 14-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TSH58p_12735 4aff559ffb09028b3660c205c8faa8b5 445 ProSitePatterns PS00104 EPSP synthase signature 1. 92 106 - T 14-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TSH58p_12735 4aff559ffb09028b3660c205c8faa8b5 445 SUPERFAMILY SSF55205 12 441 2.29E-122 T 14-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 TSH58p_12735 4aff559ffb09028b3660c205c8faa8b5 445 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 13 433 2.7E-104 T 14-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 TSH58p_12735 4aff559ffb09028b3660c205c8faa8b5 445 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 13 441 30.098 T 14-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TSH58p_12735 4aff559ffb09028b3660c205c8faa8b5 445 Gene3D G3DSA:3.65.10.10 15 435 1.1E-140 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 TSH58p_03965 59432dcae68a6257c7886893fa4d0a1e 467 Gene3D G3DSA:3.40.50.300 1 175 1.2E-43 T 14-10-2018 TSH58p_03965 59432dcae68a6257c7886893fa4d0a1e 467 SUPERFAMILY SSF52540 3 170 7.99E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_03965 59432dcae68a6257c7886893fa4d0a1e 467 Hamap MF_00195 GTPase Der [der]. 2 461 37.18 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 TSH58p_03965 59432dcae68a6257c7886893fa4d0a1e 467 SUPERFAMILY SSF52540 138 465 4.28E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_03965 59432dcae68a6257c7886893fa4d0a1e 467 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 457 6.1E-165 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 TSH58p_03965 59432dcae68a6257c7886893fa4d0a1e 467 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 124 3.3E-23 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSH58p_03965 59432dcae68a6257c7886893fa4d0a1e 467 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 200 368 6.6E-29 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSH58p_03965 59432dcae68a6257c7886893fa4d0a1e 467 Gene3D G3DSA:3.40.50.300 195 373 3.6E-50 T 14-10-2018 TSH58p_03965 59432dcae68a6257c7886893fa4d0a1e 467 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 378 458 1.4E-31 T 14-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like TSH58p_03965 59432dcae68a6257c7886893fa4d0a1e 467 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 273 291 2.5E-7 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 TSH58p_03965 59432dcae68a6257c7886893fa4d0a1e 467 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 203 223 2.5E-7 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 TSH58p_03965 59432dcae68a6257c7886893fa4d0a1e 467 Gene3D G3DSA:3.30.300.20 378 461 1.6E-31 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta TSH58p_03965 59432dcae68a6257c7886893fa4d0a1e 467 SMART SM00382 199 340 0.22 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_03965 59432dcae68a6257c7886893fa4d0a1e 467 SMART SM00382 1 142 4.3 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_03965 59432dcae68a6257c7886893fa4d0a1e 467 PIRSF PIRSF006485 1 466 5.2E-161 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 TSH58p_03965 59432dcae68a6257c7886893fa4d0a1e 467 Pfam PF01926 50S ribosome-binding GTPase 5 120 1.4E-26 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 TSH58p_03965 59432dcae68a6257c7886893fa4d0a1e 467 Pfam PF01926 50S ribosome-binding GTPase 202 320 2.4E-24 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 TSH58p_00475 980c9e02039c6df1972256b67dbafac2 667 SUPERFAMILY SSF56059 83 346 1.22E-71 T 14-10-2018 TSH58p_00475 980c9e02039c6df1972256b67dbafac2 667 Gene3D G3DSA:3.30.700.40 443 582 8.0E-7 T 14-10-2018 TSH58p_00475 980c9e02039c6df1972256b67dbafac2 667 Gene3D G3DSA:3.30.470.20 204 442 1.3E-110 T 14-10-2018 TSH58p_00475 980c9e02039c6df1972256b67dbafac2 667 SMART SM00878 335 442 6.9E-57 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TSH58p_00475 980c9e02039c6df1972256b67dbafac2 667 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TSH58p_00475 980c9e02039c6df1972256b67dbafac2 667 SUPERFAMILY SSF51246 330 446 2.56E-39 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TSH58p_00475 980c9e02039c6df1972256b67dbafac2 667 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TSH58p_00475 980c9e02039c6df1972256b67dbafac2 667 Pfam PF02785 Biotin carboxylase C-terminal domain 335 443 4.0E-38 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TSH58p_00475 980c9e02039c6df1972256b67dbafac2 667 Gene3D G3DSA:2.40.50.100 596 664 2.2E-24 T 14-10-2018 TSH58p_00475 980c9e02039c6df1972256b67dbafac2 667 Gene3D G3DSA:3.40.50.20 1 131 2.2E-55 T 14-10-2018 TSH58p_00475 980c9e02039c6df1972256b67dbafac2 667 SUPERFAMILY SSF51230 582 662 1.26E-21 T 14-10-2018 IPR011053 Single hybrid motif TSH58p_00475 980c9e02039c6df1972256b67dbafac2 667 Gene3D G3DSA:3.30.1490.20 132 202 8.6E-28 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSH58p_00475 980c9e02039c6df1972256b67dbafac2 667 Pfam PF00364 Biotin-requiring enzyme 597 660 1.9E-16 T 14-10-2018 IPR000089 Biotin/lipoyl attachment TSH58p_00475 980c9e02039c6df1972256b67dbafac2 667 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 4.5E-46 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TSH58p_00475 980c9e02039c6df1972256b67dbafac2 667 SUPERFAMILY SSF52440 1 113 5.9E-51 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TSH58p_00475 980c9e02039c6df1972256b67dbafac2 667 SMART SM01209 114 292 0.0097 T 14-10-2018 TSH58p_00475 980c9e02039c6df1972256b67dbafac2 667 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 321 1.3E-77 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TSH58p_32490 389bb555bc8e728a968b8c09a4bdda43 69 Gene3D G3DSA:2.40.50.140 1 68 8.3E-24 T 14-10-2018 TSH58p_32490 389bb555bc8e728a968b8c09a4bdda43 69 SUPERFAMILY SSF50249 1 68 3.64E-21 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_32490 389bb555bc8e728a968b8c09a4bdda43 69 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 1.2E-22 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_32490 389bb555bc8e728a968b8c09a4bdda43 69 PIRSF PIRSF002599 1 69 2.7E-21 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 TSH58p_32490 389bb555bc8e728a968b8c09a4bdda43 69 PRINTS PR00050 Cold shock protein signature 40 58 2.0E-11 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_32490 389bb555bc8e728a968b8c09a4bdda43 69 PRINTS PR00050 Cold shock protein signature 4 19 2.0E-11 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_32490 389bb555bc8e728a968b8c09a4bdda43 69 PRINTS PR00050 Cold shock protein signature 25 34 2.0E-11 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_32490 389bb555bc8e728a968b8c09a4bdda43 69 SMART SM00357 3 69 2.8E-22 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 TSH58p_32490 389bb555bc8e728a968b8c09a4bdda43 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 14-10-2018 IPR019844 Cold-shock conserved site TSH58p_00935 bd26506ef5024c737e8a10cba702a3af 609 Pfam PF12146 Serine aminopeptidase, S33 51 185 5.7E-9 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 TSH58p_00935 bd26506ef5024c737e8a10cba702a3af 609 Pfam PF12146 Serine aminopeptidase, S33 310 419 2.5E-8 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 TSH58p_00935 bd26506ef5024c737e8a10cba702a3af 609 SUPERFAMILY SSF53474 291 574 1.52E-21 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_00935 bd26506ef5024c737e8a10cba702a3af 609 Gene3D G3DSA:3.40.50.1820 18 203 2.1E-21 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_00935 bd26506ef5024c737e8a10cba702a3af 609 Gene3D G3DSA:3.40.50.1820 289 576 4.5E-23 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_00935 bd26506ef5024c737e8a10cba702a3af 609 SUPERFAMILY SSF53474 24 236 1.2E-19 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_27035 8fa6e93f434120b32b22e80ca79ef187 542 Gene3D G3DSA:3.30.565.10 374 534 4.6E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_27035 8fa6e93f434120b32b22e80ca79ef187 542 SMART SM00387 416 527 3.2E-30 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_27035 8fa6e93f434120b32b22e80ca79ef187 542 Pfam PF17158 Membrane-associated sensor, integral membrane domain 53 284 1.3E-26 T 14-10-2018 IPR033424 Membrane-associated sensor domain TSH58p_27035 8fa6e93f434120b32b22e80ca79ef187 542 SUPERFAMILY SSF55874 366 525 4.06E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_27035 8fa6e93f434120b32b22e80ca79ef187 542 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 418 525 4.2E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_27035 8fa6e93f434120b32b22e80ca79ef187 542 SUPERFAMILY SSF47384 295 370 1.22E-5 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_27035 8fa6e93f434120b32b22e80ca79ef187 542 SMART SM00388 304 374 1.1E-4 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_27035 8fa6e93f434120b32b22e80ca79ef187 542 PRINTS PR00344 Bacterial sensor protein C-terminal signature 458 472 6.0E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_27035 8fa6e93f434120b32b22e80ca79ef187 542 PRINTS PR00344 Bacterial sensor protein C-terminal signature 487 505 6.0E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_27035 8fa6e93f434120b32b22e80ca79ef187 542 PRINTS PR00344 Bacterial sensor protein C-terminal signature 511 524 6.0E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_27035 8fa6e93f434120b32b22e80ca79ef187 542 PRINTS PR00344 Bacterial sensor protein C-terminal signature 476 486 6.0E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_27035 8fa6e93f434120b32b22e80ca79ef187 542 Gene3D G3DSA:1.10.287.130 309 371 4.3E-16 T 14-10-2018 TSH58p_27035 8fa6e93f434120b32b22e80ca79ef187 542 Pfam PF00512 His Kinase A (phospho-acceptor) domain 304 367 3.1E-6 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_12765 ebf5baadcf26182cbf5dbd6e5bad1ab2 318 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 17 311 1.0E-72 T 14-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 TSH58p_12765 ebf5baadcf26182cbf5dbd6e5bad1ab2 318 PIRSF PIRSF001439 3 317 9.3E-79 T 14-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 TSH58p_12765 ebf5baadcf26182cbf5dbd6e5bad1ab2 318 Gene3D G3DSA:3.40.50.720 122 295 3.3E-92 T 14-10-2018 TSH58p_12765 ebf5baadcf26182cbf5dbd6e5bad1ab2 318 Gene3D G3DSA:3.30.1780.10 6 309 3.3E-92 T 14-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 TSH58p_12765 ebf5baadcf26182cbf5dbd6e5bad1ab2 318 SUPERFAMILY SSF51735 1 312 5.3E-94 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_10420 48e85b8297c977527523ef03dd4daa47 841 Pfam PF09397 Ftsk gamma domain 776 836 8.5E-26 T 14-10-2018 IPR018541 FtsK gamma domain TSH58p_10420 48e85b8297c977527523ef03dd4daa47 841 SMART SM00843 774 839 3.0E-36 T 14-10-2018 IPR018541 FtsK gamma domain TSH58p_10420 48e85b8297c977527523ef03dd4daa47 841 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 41 200 9.9E-30 T 14-10-2018 IPR025199 DNA translocase FtsK, 4TM region TSH58p_10420 48e85b8297c977527523ef03dd4daa47 841 Gene3D G3DSA:1.10.10.10 778 840 1.5E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_10420 48e85b8297c977527523ef03dd4daa47 841 Pfam PF01580 FtsK/SpoIIIE family 452 671 2.2E-64 T 14-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 TSH58p_10420 48e85b8297c977527523ef03dd4daa47 841 SMART SM00382 487 692 9.0E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_10420 48e85b8297c977527523ef03dd4daa47 841 SUPERFAMILY SSF52540 431 742 3.68E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_10420 48e85b8297c977527523ef03dd4daa47 841 Gene3D G3DSA:3.30.980.40 343 448 2.1E-30 T 14-10-2018 TSH58p_10420 48e85b8297c977527523ef03dd4daa47 841 Gene3D G3DSA:3.40.50.300 449 756 6.0E-113 T 14-10-2018 TSH58p_10420 48e85b8297c977527523ef03dd4daa47 841 SUPERFAMILY SSF46785 774 837 2.34E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_06925 00b83ee9650f184161c2d26eea4b041b 360 Gene3D G3DSA:3.30.470.20 182 360 8.9E-76 T 14-10-2018 TSH58p_06925 00b83ee9650f184161c2d26eea4b041b 360 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 11 356 7.2E-116 T 14-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 TSH58p_06925 00b83ee9650f184161c2d26eea4b041b 360 Gene3D G3DSA:3.40.50.20 5 112 2.2E-35 T 14-10-2018 TSH58p_06925 00b83ee9650f184161c2d26eea4b041b 360 Gene3D G3DSA:3.30.1490.20 113 181 1.2E-21 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSH58p_06925 00b83ee9650f184161c2d26eea4b041b 360 SUPERFAMILY SSF51246 311 357 1.26E-12 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TSH58p_06925 00b83ee9650f184161c2d26eea4b041b 360 Pfam PF02222 ATP-grasp domain 118 286 7.7E-59 T 14-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type TSH58p_06925 00b83ee9650f184161c2d26eea4b041b 360 SUPERFAMILY SSF52440 5 104 5.04E-22 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TSH58p_06925 00b83ee9650f184161c2d26eea4b041b 360 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 11 360 40.694 T 14-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 TSH58p_06925 00b83ee9650f184161c2d26eea4b041b 360 SUPERFAMILY SSF56059 108 305 9.72E-63 T 14-10-2018 TSH58p_09765 199b10ec0a9474496646b78c498f0acb 158 Pfam PF02308 MgtC family 16 144 1.3E-28 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 TSH58p_09765 199b10ec0a9474496646b78c498f0acb 158 PRINTS PR01837 MgtC/SapB protein signature 75 97 1.8E-36 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 TSH58p_09765 199b10ec0a9474496646b78c498f0acb 158 PRINTS PR01837 MgtC/SapB protein signature 102 126 1.8E-36 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 TSH58p_09765 199b10ec0a9474496646b78c498f0acb 158 PRINTS PR01837 MgtC/SapB protein signature 19 38 1.8E-36 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 TSH58p_09765 199b10ec0a9474496646b78c498f0acb 158 PRINTS PR01837 MgtC/SapB protein signature 38 56 1.8E-36 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 TSH58p_05050 8dce0fac3605068bad9f73e08ca36e13 436 SUPERFAMILY SSF54373 270 360 5.49E-17 T 14-10-2018 TSH58p_05050 8dce0fac3605068bad9f73e08ca36e13 436 Gene3D G3DSA:3.50.50.60 107 404 4.2E-58 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_05050 8dce0fac3605068bad9f73e08ca36e13 436 Hamap MF_01202 D-amino acid dehydrogenase [dadA]. 1 411 48.72 T 14-10-2018 IPR023080 D-amino acid dehydrogenase DadA GO:0008718|GO:0019478|GO:0055114 TSH58p_05050 8dce0fac3605068bad9f73e08ca36e13 436 Gene3D G3DSA:3.30.9.10 134 362 4.2E-58 T 14-10-2018 TSH58p_05050 8dce0fac3605068bad9f73e08ca36e13 436 SUPERFAMILY SSF51905 1 419 5.05E-58 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_05050 8dce0fac3605068bad9f73e08ca36e13 436 Pfam PF01266 FAD dependent oxidoreductase 2 397 1.6E-76 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TSH58p_05050 8dce0fac3605068bad9f73e08ca36e13 436 Gene3D G3DSA:3.50.50.60 1 76 2.2E-12 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_21610 c619cf1a7fcccbfb5634b5f696811460 788 SMART SM00732 324 423 8.5E-37 T 14-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 TSH58p_21610 c619cf1a7fcccbfb5634b5f696811460 788 Gene3D G3DSA:1.10.3500.10 113 497 3.4E-152 T 14-10-2018 IPR023323 Tex-like domain superfamily TSH58p_21610 c619cf1a7fcccbfb5634b5f696811460 788 SUPERFAMILY SSF53098 320 468 4.02E-50 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily TSH58p_21610 c619cf1a7fcccbfb5634b5f696811460 788 Pfam PF12836 Helix-hairpin-helix motif 490 554 2.9E-28 T 14-10-2018 TSH58p_21610 c619cf1a7fcccbfb5634b5f696811460 788 Gene3D G3DSA:1.10.150.310 498 629 2.3E-50 T 14-10-2018 TSH58p_21610 c619cf1a7fcccbfb5634b5f696811460 788 SUPERFAMILY SSF158832 4 319 1.7E-119 T 14-10-2018 TSH58p_21610 c619cf1a7fcccbfb5634b5f696811460 788 SUPERFAMILY SSF47781 469 557 2.67E-27 T 14-10-2018 IPR010994 RuvA domain 2-like TSH58p_21610 c619cf1a7fcccbfb5634b5f696811460 788 SUPERFAMILY SSF50249 636 725 7.46E-25 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_21610 c619cf1a7fcccbfb5634b5f696811460 788 Gene3D G3DSA:2.40.50.140 630 723 5.2E-28 T 14-10-2018 TSH58p_21610 c619cf1a7fcccbfb5634b5f696811460 788 SUPERFAMILY SSF47781 559 631 5.78E-20 T 14-10-2018 IPR010994 RuvA domain 2-like TSH58p_21610 c619cf1a7fcccbfb5634b5f696811460 788 SMART SM00316 648 719 1.2E-23 T 14-10-2018 IPR022967 RNA-binding domain, S1 TSH58p_21610 c619cf1a7fcccbfb5634b5f696811460 788 Pfam PF16921 Tex protein YqgF-like domain 325 450 9.3E-51 T 14-10-2018 IPR032639 Tex protein, YqgF-like domain TSH58p_21610 c619cf1a7fcccbfb5634b5f696811460 788 Pfam PF09371 Tex-like protein N-terminal domain 10 194 1.2E-69 T 14-10-2018 IPR018974 Tex-like protein, N-terminal TSH58p_21610 c619cf1a7fcccbfb5634b5f696811460 788 Pfam PF00575 S1 RNA binding domain 647 719 4.7E-20 T 14-10-2018 IPR003029 S1 domain GO:0003676 TSH58p_21610 c619cf1a7fcccbfb5634b5f696811460 788 Gene3D G3DSA:3.30.420.140 323 450 3.4E-152 T 14-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 TSH58p_21610 c619cf1a7fcccbfb5634b5f696811460 788 Gene3D G3DSA:1.10.10.650 3 110 3.0E-41 T 14-10-2018 IPR023319 Tex-like protein, HTH domain superfamily TSH58p_09385 c57414a4918e708239c59641eb628d80 559 SUPERFAMILY SSF58104 239 552 6.15E-60 T 14-10-2018 TSH58p_09385 c57414a4918e708239c59641eb628d80 559 SMART SM00283 299 553 2.0E-45 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_09385 c57414a4918e708239c59641eb628d80 559 Pfam PF00672 HAMP domain 212 258 3.1E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_09385 c57414a4918e708239c59641eb628d80 559 Gene3D G3DSA:1.20.1480.50 170 268 2.2E-14 T 14-10-2018 TSH58p_09385 c57414a4918e708239c59641eb628d80 559 Pfam PF12729 Four helix bundle sensory module for signal transduction 4 183 1.9E-30 T 14-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain TSH58p_09385 c57414a4918e708239c59641eb628d80 559 Gene3D G3DSA:1.10.287.950 269 556 2.6E-53 T 14-10-2018 TSH58p_09385 c57414a4918e708239c59641eb628d80 559 SMART SM00304 210 263 3.5E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_09385 c57414a4918e708239c59641eb628d80 559 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 474 503 1.7E-21 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_09385 c57414a4918e708239c59641eb628d80 559 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 1 24 1.7E-21 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_09385 c57414a4918e708239c59641eb628d80 559 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 426 455 1.7E-21 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_09385 c57414a4918e708239c59641eb628d80 559 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 397 424 1.7E-21 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_09385 c57414a4918e708239c59641eb628d80 559 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 366 521 1.7E-30 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_05665 fa082f5c659edac1c557036820b63d50 726 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 281 474 5.8E-25 T 14-10-2018 IPR004477 ComEC/Rec2-related protein TSH58p_05665 fa082f5c659edac1c557036820b63d50 726 Pfam PF03772 Competence protein 260 543 1.5E-61 T 14-10-2018 IPR004477 ComEC/Rec2-related protein TSH58p_05665 fa082f5c659edac1c557036820b63d50 726 Pfam PF13567 Domain of unknown function (DUF4131) 60 214 4.3E-14 T 14-10-2018 IPR025405 Domain of unknown function DUF4131 TSH58p_26690 e515f89ee6d584d6617496135a462b19 415 SUPERFAMILY SSF89796 5 396 1.83E-121 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily TSH58p_26690 e515f89ee6d584d6617496135a462b19 415 Pfam PF02515 CoA-transferase family III 8 373 1.7E-109 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 TSH58p_26690 e515f89ee6d584d6617496135a462b19 415 Gene3D G3DSA:3.30.1540.10 232 325 1.6E-123 T 14-10-2018 TSH58p_26690 e515f89ee6d584d6617496135a462b19 415 Gene3D G3DSA:3.40.50.10540 8 390 1.6E-123 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily TSH58p_11635 a6e7eaef313f1509991e0eb43dbb9450 295 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 109 196 7.3E-11 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_11635 a6e7eaef313f1509991e0eb43dbb9450 295 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 207 288 8.1E-16 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_11635 a6e7eaef313f1509991e0eb43dbb9450 295 Gene3D G3DSA:1.20.58.1490 1 69 4.3E-20 T 14-10-2018 IPR038414 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal domain superfamily TSH58p_11635 a6e7eaef313f1509991e0eb43dbb9450 295 PIRSF PIRSF000006 1 295 2.8E-112 T 14-10-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III TSH58p_11635 a6e7eaef313f1509991e0eb43dbb9450 295 SUPERFAMILY SSF46626 204 293 6.49E-26 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_11635 a6e7eaef313f1509991e0eb43dbb9450 295 SUPERFAMILY SSF46626 30 202 1.95E-27 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_11635 a6e7eaef313f1509991e0eb43dbb9450 295 TIGRFAM TIGR00782 ccoP: cytochrome c oxidase, cbb3-type, subunit III 7 294 1.4E-100 T 14-10-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III TSH58p_11635 a6e7eaef313f1509991e0eb43dbb9450 295 Pfam PF14715 N-terminal domain of cytochrome oxidase-cbb3, FixP 11 57 1.5E-24 T 14-10-2018 IPR032858 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal TSH58p_11635 a6e7eaef313f1509991e0eb43dbb9450 295 Gene3D G3DSA:1.10.760.10 175 268 2.6E-62 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_11635 a6e7eaef313f1509991e0eb43dbb9450 295 PRINTS PR00605 Class IC cytochrome C signature 266 288 5.1E-9 T 14-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 TSH58p_11635 a6e7eaef313f1509991e0eb43dbb9450 295 PRINTS PR00605 Class IC cytochrome C signature 119 130 5.1E-9 T 14-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 TSH58p_11635 a6e7eaef313f1509991e0eb43dbb9450 295 Gene3D G3DSA:1.10.760.10 82 291 2.6E-62 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_27740 221e29733a7c0eb424b0436522d4927e 424 PIRSF PIRSF006066 1 424 1.2E-124 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSH58p_27740 221e29733a7c0eb424b0436522d4927e 424 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 8 418 9.4E-104 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TSH58p_27740 221e29733a7c0eb424b0436522d4927e 424 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 21 422 1.4E-116 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSH58p_06380 7c23f951060623d914e38e8a29deacce 613 PRINTS PR00762 Chloride channel signature 142 161 5.9E-5 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 TSH58p_06380 7c23f951060623d914e38e8a29deacce 613 PRINTS PR00762 Chloride channel signature 193 212 5.9E-5 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 TSH58p_06380 7c23f951060623d914e38e8a29deacce 613 Pfam PF00654 Voltage gated chloride channel 100 439 1.1E-54 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 TSH58p_06380 7c23f951060623d914e38e8a29deacce 613 Gene3D G3DSA:3.10.580.10 469 590 1.7E-5 T 14-10-2018 TSH58p_06380 7c23f951060623d914e38e8a29deacce 613 Gene3D G3DSA:1.10.3080.10 43 453 6.8E-61 T 14-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 TSH58p_06380 7c23f951060623d914e38e8a29deacce 613 SUPERFAMILY SSF54631 470 599 5.47E-8 T 14-10-2018 TSH58p_06380 7c23f951060623d914e38e8a29deacce 613 SUPERFAMILY SSF81340 28 462 9.42E-79 T 14-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 TSH58p_21750 208b14a7dc624207cb936dab9d1f9a80 409 Gene3D G3DSA:2.40.30.170 75 318 1.4E-91 T 14-10-2018 TSH58p_21750 208b14a7dc624207cb936dab9d1f9a80 409 Gene3D G3DSA:2.40.50.100 86 230 1.4E-91 T 14-10-2018 TSH58p_21750 208b14a7dc624207cb936dab9d1f9a80 409 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 87 308 1.0E-18 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain TSH58p_21750 208b14a7dc624207cb936dab9d1f9a80 409 SUPERFAMILY SSF111369 78 312 3.79E-58 T 14-10-2018 TSH58p_21750 208b14a7dc624207cb936dab9d1f9a80 409 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 62 389 4.7E-82 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 TSH58p_21750 208b14a7dc624207cb936dab9d1f9a80 409 Gene3D G3DSA:1.10.287.470 121 194 1.4E-91 T 14-10-2018 TSH58p_21750 208b14a7dc624207cb936dab9d1f9a80 409 Gene3D G3DSA:2.40.420.20 319 387 1.4E-91 T 14-10-2018 TSH58p_26595 fda1775339d9b21625f958a05b6abbad 257 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 256 1.1E-28 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_26595 fda1775339d9b21625f958a05b6abbad 257 Gene3D G3DSA:3.40.190.10 44 254 3.2E-31 T 14-10-2018 TSH58p_26595 fda1775339d9b21625f958a05b6abbad 257 Gene3D G3DSA:3.40.190.10 122 217 3.2E-31 T 14-10-2018 TSH58p_26595 fda1775339d9b21625f958a05b6abbad 257 SUPERFAMILY SSF53850 40 255 5.92E-41 T 14-10-2018 TSH58p_26595 fda1775339d9b21625f958a05b6abbad 257 SMART SM00062 38 257 4.5E-12 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_21830 97df6e24d5017ec5baeb35eba58631ed 493 Pfam PF08443 RimK-like ATP-grasp domain 284 458 1.2E-8 T 14-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 TSH58p_21830 97df6e24d5017ec5baeb35eba58631ed 493 Gene3D G3DSA:3.40.50.20 214 298 3.8E-6 T 14-10-2018 TSH58p_21830 97df6e24d5017ec5baeb35eba58631ed 493 SUPERFAMILY SSF56059 275 480 1.71E-37 T 14-10-2018 TSH58p_21830 97df6e24d5017ec5baeb35eba58631ed 493 Pfam PF14401 RimK-like ATPgrasp N-terminal domain 27 174 3.7E-46 T 14-10-2018 IPR025839 RimK-like ATPgrasp N-terminal domain TSH58p_21830 97df6e24d5017ec5baeb35eba58631ed 493 Gene3D G3DSA:3.30.1490.20 300 363 1.8E-8 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSH58p_21830 97df6e24d5017ec5baeb35eba58631ed 493 Gene3D G3DSA:3.30.470.20 364 476 1.6E-16 T 14-10-2018 TSH58p_25735 243d43cee5977ea519df52fec0eec95e 972 SUPERFAMILY SSF50692 769 972 1.47E-38 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TSH58p_25735 243d43cee5977ea519df52fec0eec95e 972 SUPERFAMILY SSF53706 74 625 7.33E-190 T 14-10-2018 TSH58p_25735 243d43cee5977ea519df52fec0eec95e 972 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 80 97 - T 14-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 TSH58p_25735 243d43cee5977ea519df52fec0eec95e 972 Gene3D G3DSA:3.40.228.10 209 408 1.5E-132 T 14-10-2018 TSH58p_25735 243d43cee5977ea519df52fec0eec95e 972 Gene3D G3DSA:2.20.25.90 77 128 3.4E-9 T 14-10-2018 TSH58p_25735 243d43cee5977ea519df52fec0eec95e 972 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 78 126 9.2E-10 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_25735 243d43cee5977ea519df52fec0eec95e 972 Pfam PF01568 Molydopterin dinucleotide binding domain 837 965 1.8E-20 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TSH58p_25735 243d43cee5977ea519df52fec0eec95e 972 Gene3D G3DSA:3.40.50.740 141 625 1.5E-132 T 14-10-2018 TSH58p_25735 243d43cee5977ea519df52fec0eec95e 972 Gene3D G3DSA:2.40.40.20 783 972 9.1E-41 T 14-10-2018 TSH58p_25735 243d43cee5977ea519df52fec0eec95e 972 SMART SM00926 75 129 3.4E-10 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_25735 243d43cee5977ea519df52fec0eec95e 972 Pfam PF00384 Molybdopterin oxidoreductase 132 577 9.8E-56 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_25735 243d43cee5977ea519df52fec0eec95e 972 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 34 66 2.6E-4 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal TSH58p_29750 e852fdd5baeb36d8f7678b9303390aa3 373 Gene3D G3DSA:2.40.420.20 296 363 3.8E-75 T 14-10-2018 TSH58p_29750 e852fdd5baeb36d8f7678b9303390aa3 373 SUPERFAMILY SSF111369 74 290 2.35E-42 T 14-10-2018 TSH58p_29750 e852fdd5baeb36d8f7678b9303390aa3 373 Gene3D G3DSA:1.10.287.470 119 178 3.8E-75 T 14-10-2018 TSH58p_29750 e852fdd5baeb36d8f7678b9303390aa3 373 Gene3D G3DSA:2.40.50.100 84 212 3.8E-75 T 14-10-2018 TSH58p_29750 e852fdd5baeb36d8f7678b9303390aa3 373 Gene3D G3DSA:2.40.30.170 71 295 3.8E-75 T 14-10-2018 TSH58p_29750 e852fdd5baeb36d8f7678b9303390aa3 373 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 70 285 1.9E-30 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain TSH58p_29750 e852fdd5baeb36d8f7678b9303390aa3 373 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 61 365 1.6E-79 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 TSH58p_02425 b617961abef4ef76b96992df1464212f 159 SUPERFAMILY SSF46785 2 148 6.4E-36 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_02425 b617961abef4ef76b96992df1464212f 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 92 108 3.4E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_02425 b617961abef4ef76b96992df1464212f 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 73 88 3.4E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_02425 b617961abef4ef76b96992df1464212f 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 56 72 3.4E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_02425 b617961abef4ef76b96992df1464212f 159 SMART SM00347 32 132 8.8E-24 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_02425 b617961abef4ef76b96992df1464212f 159 Gene3D G3DSA:1.10.10.10 4 147 3.8E-36 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_02425 b617961abef4ef76b96992df1464212f 159 Pfam PF01047 MarR family 39 97 1.9E-16 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_01695 bc58976225be7d328f211ac47fe52e9e 572 Gene3D G3DSA:1.10.443.10 365 547 7.3E-14 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TSH58p_01695 bc58976225be7d328f211ac47fe52e9e 572 SUPERFAMILY SSF56349 383 541 2.74E-14 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TSH58p_01695 bc58976225be7d328f211ac47fe52e9e 572 Pfam PF00589 Phage integrase family 371 540 2.5E-10 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TSH58p_04780 f35f29d766b1601541b327dc4b57f41a 487 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 44 104 1.9E-8 T 14-10-2018 IPR029095 NarX-like, N-terminal TSH58p_04780 f35f29d766b1601541b327dc4b57f41a 487 Pfam PF00512 His Kinase A (phospho-acceptor) domain 259 324 1.7E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_04780 f35f29d766b1601541b327dc4b57f41a 487 Gene3D G3DSA:1.10.287.130 219 322 2.2E-16 T 14-10-2018 TSH58p_04780 f35f29d766b1601541b327dc4b57f41a 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 457 7.2E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_04780 f35f29d766b1601541b327dc4b57f41a 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 418 7.2E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_04780 f35f29d766b1601541b327dc4b57f41a 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 476 7.2E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_04780 f35f29d766b1601541b327dc4b57f41a 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 432 7.2E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_04780 f35f29d766b1601541b327dc4b57f41a 487 SUPERFAMILY SSF55874 313 477 9.95E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_04780 f35f29d766b1601541b327dc4b57f41a 487 SMART SM00388 259 324 1.6E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_04780 f35f29d766b1601541b327dc4b57f41a 487 SUPERFAMILY SSF47384 245 324 3.73E-13 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_04780 f35f29d766b1601541b327dc4b57f41a 487 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 370 477 2.1E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_04780 f35f29d766b1601541b327dc4b57f41a 487 Gene3D G3DSA:3.30.565.10 331 482 9.9E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_04780 f35f29d766b1601541b327dc4b57f41a 487 SMART SM00387 368 479 3.3E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_18865 b1b9e6f5aa7a6d8a4116114671bd423f 515 Gene3D G3DSA:2.60.40.420 393 512 3.2E-37 T 14-10-2018 IPR008972 Cupredoxin TSH58p_18865 b1b9e6f5aa7a6d8a4116114671bd423f 515 Pfam PF00394 Multicopper oxidase 253 354 1.7E-13 T 14-10-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 TSH58p_18865 b1b9e6f5aa7a6d8a4116114671bd423f 515 Pfam PF07731 Multicopper oxidase 401 511 7.8E-29 T 14-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 TSH58p_18865 b1b9e6f5aa7a6d8a4116114671bd423f 515 Gene3D G3DSA:2.60.40.420 160 372 2.7E-23 T 14-10-2018 IPR008972 Cupredoxin TSH58p_18865 b1b9e6f5aa7a6d8a4116114671bd423f 515 ProSitePatterns PS00079 Multicopper oxidases signature 1. 489 509 - T 14-10-2018 IPR033138 Multicopper oxidases, conserved site TSH58p_18865 b1b9e6f5aa7a6d8a4116114671bd423f 515 Gene3D G3DSA:2.60.40.420 39 156 4.5E-16 T 14-10-2018 IPR008972 Cupredoxin TSH58p_18865 b1b9e6f5aa7a6d8a4116114671bd423f 515 SUPERFAMILY SSF49503 40 156 5.26E-15 T 14-10-2018 IPR008972 Cupredoxin TSH58p_18865 b1b9e6f5aa7a6d8a4116114671bd423f 515 Pfam PF07732 Multicopper oxidase 72 154 1.6E-13 T 14-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 TSH58p_18865 b1b9e6f5aa7a6d8a4116114671bd423f 515 ProSitePatterns PS00080 Multicopper oxidases signature 2. 494 505 - T 14-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 TSH58p_18865 b1b9e6f5aa7a6d8a4116114671bd423f 515 SUPERFAMILY SSF49503 381 509 3.51E-36 T 14-10-2018 IPR008972 Cupredoxin TSH58p_18865 b1b9e6f5aa7a6d8a4116114671bd423f 515 SUPERFAMILY SSF49503 162 350 1.44E-21 T 14-10-2018 IPR008972 Cupredoxin TSH58p_20965 e89e88350aa49c567ec7e2b49c984e98 256 SMART SM00866 106 248 5.3E-20 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 TSH58p_20965 e89e88350aa49c567ec7e2b49c984e98 256 Gene3D G3DSA:1.10.10.10 12 86 1.5E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_20965 e89e88350aa49c567ec7e2b49c984e98 256 SUPERFAMILY SSF46785 19 89 2.58E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_20965 e89e88350aa49c567ec7e2b49c984e98 256 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 83 3.6E-21 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_20965 e89e88350aa49c567ec7e2b49c984e98 256 Gene3D G3DSA:3.40.1410.10 93 253 3.0E-30 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TSH58p_20965 e89e88350aa49c567ec7e2b49c984e98 256 SMART SM00345 26 85 2.9E-22 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_20965 e89e88350aa49c567ec7e2b49c984e98 256 Pfam PF07702 UTRA domain 112 247 1.1E-22 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 TSH58p_20965 e89e88350aa49c567ec7e2b49c984e98 256 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 59 5.4E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_20965 e89e88350aa49c567ec7e2b49c984e98 256 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 59 75 5.4E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_20965 e89e88350aa49c567ec7e2b49c984e98 256 SUPERFAMILY SSF64288 73 255 1.15E-33 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TSH58p_06830 9e2cf57bfac109620fd011fd3772a4a0 271 Gene3D G3DSA:3.40.50.720 3 165 1.3E-36 T 14-10-2018 TSH58p_06830 9e2cf57bfac109620fd011fd3772a4a0 271 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 9 269 3.6E-72 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TSH58p_06830 9e2cf57bfac109620fd011fd3772a4a0 271 PIRSF PIRSF000193 5 271 5.2E-56 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TSH58p_06830 9e2cf57bfac109620fd011fd3772a4a0 271 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 5 269 24.74 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TSH58p_06830 9e2cf57bfac109620fd011fd3772a4a0 271 Gene3D G3DSA:1.10.3730.10 166 271 2.9E-37 T 14-10-2018 TSH58p_06830 9e2cf57bfac109620fd011fd3772a4a0 271 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 11 100 3.9E-6 T 14-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal TSH58p_06830 9e2cf57bfac109620fd011fd3772a4a0 271 SUPERFAMILY SSF51735 7 161 1.21E-24 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_06830 9e2cf57bfac109620fd011fd3772a4a0 271 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 164 269 4.7E-33 T 14-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TSH58p_06830 9e2cf57bfac109620fd011fd3772a4a0 271 SUPERFAMILY SSF48179 163 270 1.36E-30 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_28000 2465ab50c11f2388e4984632882b2bf3 482 Gene3D G3DSA:3.30.750.44 97 387 2.1E-88 T 14-10-2018 TSH58p_28000 2465ab50c11f2388e4984632882b2bf3 482 SMART SM00228 139 212 1.2E-14 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_28000 2465ab50c11f2388e4984632882b2bf3 482 Pfam PF13180 PDZ domain 139 213 1.2E-11 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_28000 2465ab50c11f2388e4984632882b2bf3 482 Gene3D G3DSA:3.90.226.10 236 409 2.1E-88 T 14-10-2018 TSH58p_28000 2465ab50c11f2388e4984632882b2bf3 482 Pfam PF03572 Peptidase family S41 245 410 8.3E-45 T 14-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 TSH58p_28000 2465ab50c11f2388e4984632882b2bf3 482 SUPERFAMILY SSF52096 91 416 7.46E-65 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_28000 2465ab50c11f2388e4984632882b2bf3 482 SUPERFAMILY SSF50156 127 213 5.84E-19 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 TSH58p_28000 2465ab50c11f2388e4984632882b2bf3 482 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 102 420 3.9E-86 T 14-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 TSH58p_28000 2465ab50c11f2388e4984632882b2bf3 482 SMART SM00245 221 412 1.4E-58 T 14-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 TSH58p_28000 2465ab50c11f2388e4984632882b2bf3 482 Gene3D G3DSA:2.30.42.10 139 235 2.1E-88 T 14-10-2018 TSH58p_31725 92304c2e4557faa97e260d3ea6fbdf99 370 Pfam PF00005 ABC transporter 19 161 1.7E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_31725 92304c2e4557faa97e260d3ea6fbdf99 370 Gene3D G3DSA:3.40.50.300 1 238 2.4E-78 T 14-10-2018 TSH58p_31725 92304c2e4557faa97e260d3ea6fbdf99 370 SMART SM00382 28 211 3.1E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_31725 92304c2e4557faa97e260d3ea6fbdf99 370 SUPERFAMILY SSF50331 274 363 2.55E-6 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSH58p_31725 92304c2e4557faa97e260d3ea6fbdf99 370 Pfam PF08402 TOBE domain 294 362 2.6E-4 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TSH58p_31725 92304c2e4557faa97e260d3ea6fbdf99 370 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_31725 92304c2e4557faa97e260d3ea6fbdf99 370 SUPERFAMILY SSF52540 4 242 1.69E-82 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_05200 22a2c80feb74c5750781eaf6e6ee03c4 340 Gene3D G3DSA:3.40.50.720 1 193 4.7E-66 T 14-10-2018 TSH58p_05200 22a2c80feb74c5750781eaf6e6ee03c4 340 SUPERFAMILY SSF48179 197 316 5.95E-30 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_05200 22a2c80feb74c5750781eaf6e6ee03c4 340 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 197 316 4.7E-28 T 14-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain TSH58p_05200 22a2c80feb74c5750781eaf6e6ee03c4 340 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 104 8.0E-24 T 14-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain TSH58p_05200 22a2c80feb74c5750781eaf6e6ee03c4 340 Gene3D G3DSA:1.10.1040.10 196 330 1.4E-43 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSH58p_05200 22a2c80feb74c5750781eaf6e6ee03c4 340 SUPERFAMILY SSF51735 1 184 3.94E-16 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_15765 ee4ac4ec14fc40decbdf1b8cbcb6fb65 883 SUPERFAMILY SSF51445 43 308 4.08E-41 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_15765 ee4ac4ec14fc40decbdf1b8cbcb6fb65 883 SUPERFAMILY SSF53448 415 670 4.58E-47 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_15765 ee4ac4ec14fc40decbdf1b8cbcb6fb65 883 Gene3D G3DSA:3.90.550.10 417 639 8.3E-58 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_15765 ee4ac4ec14fc40decbdf1b8cbcb6fb65 883 Pfam PF13641 Glycosyltransferase like family 2 427 655 1.9E-29 T 14-10-2018 TSH58p_15765 ee4ac4ec14fc40decbdf1b8cbcb6fb65 883 Gene3D G3DSA:3.20.20.80 113 309 1.2E-9 T 14-10-2018 TSH58p_09540 c312ac50f3acdb2f81b55feea67e9f03 509 TIGRFAM TIGR01717 AMP-nucleosdse: AMP nucleosidase 23 509 1.8E-194 T 14-10-2018 IPR011271 AMP nucleosidase GO:0008714|GO:0009116|GO:0044209 KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 TSH58p_09540 c312ac50f3acdb2f81b55feea67e9f03 509 Pfam PF10423 Bacterial AMP nucleoside phosphorylase N-terminus 24 175 2.9E-51 T 14-10-2018 IPR018953 AMP nucleoside phosphorylase, N-terminal KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 TSH58p_09540 c312ac50f3acdb2f81b55feea67e9f03 509 Hamap MF_01932 AMP nucleosidase [amn]. 15 509 60.624 T 14-10-2018 IPR011271 AMP nucleosidase GO:0008714|GO:0009116|GO:0044209 KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 TSH58p_09540 c312ac50f3acdb2f81b55feea67e9f03 509 SUPERFAMILY SSF53167 20 509 4.9E-145 T 14-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TSH58p_09540 c312ac50f3acdb2f81b55feea67e9f03 509 Gene3D G3DSA:3.30.1730.10 17 183 1.2E-48 T 14-10-2018 IPR037109 AMP nucleoside phosphorylase, N-terminal domain superfamily KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 TSH58p_09540 c312ac50f3acdb2f81b55feea67e9f03 509 Gene3D G3DSA:3.40.50.1580 184 509 1.6E-98 T 14-10-2018 TSH58p_09540 c312ac50f3acdb2f81b55feea67e9f03 509 Pfam PF01048 Phosphorylase superfamily 264 456 3.5E-14 T 14-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 SMART SM00448 928 1042 1.8E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 SMART SM00387 797 908 4.3E-30 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 Gene3D G3DSA:3.40.50.2300 925 1054 1.4E-19 T 14-10-2018 TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 SMART SM00388 686 751 3.0E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 SUPERFAMILY SSF55785 315 417 1.92E-10 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 Pfam PF00512 His Kinase A (phospho-acceptor) domain 686 751 1.7E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 Gene3D G3DSA:2.10.70.100 622 665 9.7E-9 T 14-10-2018 TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 Gene3D G3DSA:2.10.70.100 495 539 9.7E-13 T 14-10-2018 TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 SMART SM00086 625 666 7.0E-5 T 14-10-2018 IPR001610 PAC motif TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 SMART SM00086 496 538 0.0056 T 14-10-2018 IPR001610 PAC motif TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 Gene3D G3DSA:1.10.287.130 666 749 1.0E-16 T 14-10-2018 TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 Pfam PF02743 Cache domain 39 209 3.3E-17 T 14-10-2018 IPR033479 Double Cache domain 1 TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 Gene3D G3DSA:3.30.450.20 416 485 9.1E-17 T 14-10-2018 TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 Gene3D G3DSA:3.30.450.20 546 617 1.5E-20 T 14-10-2018 TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 444 545 1.1E-5 T 14-10-2018 IPR000014 PAS domain TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 546 673 6.5E-12 T 14-10-2018 IPR000014 PAS domain TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 PRINTS PR00344 Bacterial sensor protein C-terminal signature 868 886 2.4E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 PRINTS PR00344 Bacterial sensor protein C-terminal signature 892 905 2.4E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 PRINTS PR00344 Bacterial sensor protein C-terminal signature 851 861 2.4E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 PRINTS PR00344 Bacterial sensor protein C-terminal signature 833 847 2.4E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 800 906 2.3E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 SUPERFAMILY SSF52172 931 1050 5.55E-20 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 Pfam PF08447 PAS fold 573 659 3.9E-17 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 Pfam PF08447 PAS fold 444 531 4.2E-13 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 Pfam PF00072 Response regulator receiver domain 931 1042 3.3E-11 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 SUPERFAMILY SSF55874 740 909 1.83E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 SUPERFAMILY SSF55785 405 536 2.97E-16 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 Gene3D G3DSA:3.30.450.20 295 407 6.8E-20 T 14-10-2018 TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 Gene3D G3DSA:3.30.450.20 22 164 2.5E-21 T 14-10-2018 TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 SUPERFAMILY SSF47384 669 751 3.73E-15 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 SUPERFAMILY SSF55785 535 664 4.19E-25 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 SMART SM00091 550 618 3.0E-5 T 14-10-2018 IPR000014 PAS domain TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 SMART SM00091 304 370 0.008 T 14-10-2018 IPR000014 PAS domain TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 SMART SM00091 420 490 13.0 T 14-10-2018 IPR000014 PAS domain TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 Gene3D G3DSA:3.30.565.10 759 909 1.0E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_02940 2dc8c3563f8178a68eb4408ec3100a89 1056 Pfam PF08448 PAS fold 312 410 1.5E-6 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_28480 516e8d5eb96f3a1541560d2622569daf 956 Gene3D G3DSA:3.30.65.10 610 651 5.2E-5 T 14-10-2018 TSH58p_28480 516e8d5eb96f3a1541560d2622569daf 956 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 288 310 - T 14-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 TSH58p_28480 516e8d5eb96f3a1541560d2622569daf 956 Pfam PF01751 Toprim domain 6 118 9.0E-26 T 14-10-2018 IPR006171 TOPRIM domain TSH58p_28480 516e8d5eb96f3a1541560d2622569daf 956 SUPERFAMILY SSF57783 609 647 7.31E-9 T 14-10-2018 TSH58p_28480 516e8d5eb96f3a1541560d2622569daf 956 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 610 644 9.2E-12 T 14-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 TSH58p_28480 516e8d5eb96f3a1541560d2622569daf 956 Gene3D G3DSA:3.40.50.140 3 139 1.0E-48 T 14-10-2018 TSH58p_28480 516e8d5eb96f3a1541560d2622569daf 956 Pfam PF01131 DNA topoisomerase 134 560 6.0E-126 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TSH58p_28480 516e8d5eb96f3a1541560d2622569daf 956 Gene3D G3DSA:1.10.460.10 143 563 2.4E-168 T 14-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 TSH58p_28480 516e8d5eb96f3a1541560d2622569daf 956 Gene3D G3DSA:2.70.20.10 189 470 2.4E-168 T 14-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 TSH58p_28480 516e8d5eb96f3a1541560d2622569daf 956 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 7 643 2.3E-237 T 14-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 TSH58p_28480 516e8d5eb96f3a1541560d2622569daf 956 SMART SM00436 109 197 1.1E-41 T 14-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 TSH58p_28480 516e8d5eb96f3a1541560d2622569daf 956 Pfam PF13368 Topoisomerase C-terminal repeat 753 805 1.2E-18 T 14-10-2018 IPR025589 Topoisomerase C-terminal repeat TSH58p_28480 516e8d5eb96f3a1541560d2622569daf 956 Pfam PF13368 Topoisomerase C-terminal repeat 664 749 7.1E-13 T 14-10-2018 IPR025589 Topoisomerase C-terminal repeat TSH58p_28480 516e8d5eb96f3a1541560d2622569daf 956 Pfam PF13368 Topoisomerase C-terminal repeat 815 867 8.3E-22 T 14-10-2018 IPR025589 Topoisomerase C-terminal repeat TSH58p_28480 516e8d5eb96f3a1541560d2622569daf 956 SUPERFAMILY SSF56712 5 617 1.31E-185 T 14-10-2018 IPR023405 DNA topoisomerase, type IA, core domain TSH58p_28480 516e8d5eb96f3a1541560d2622569daf 956 SMART SM00437 251 523 2.4E-123 T 14-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 TSH58p_28480 516e8d5eb96f3a1541560d2622569daf 956 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 301 310 9.2E-35 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TSH58p_28480 516e8d5eb96f3a1541560d2622569daf 956 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 486 500 9.2E-35 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TSH58p_28480 516e8d5eb96f3a1541560d2622569daf 956 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 78 91 9.2E-35 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TSH58p_28480 516e8d5eb96f3a1541560d2622569daf 956 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 379 395 9.2E-35 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TSH58p_28480 516e8d5eb96f3a1541560d2622569daf 956 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 167 185 9.2E-35 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TSH58p_28480 516e8d5eb96f3a1541560d2622569daf 956 Gene3D G3DSA:1.10.290.10 259 394 2.4E-168 T 14-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 TSH58p_28480 516e8d5eb96f3a1541560d2622569daf 956 Hamap MF_00952 DNA topoisomerase 1 [topA]. 4 774 54.649 T 14-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 TSH58p_28480 516e8d5eb96f3a1541560d2622569daf 956 SMART SM00493 4 104 3.4E-29 T 14-10-2018 IPR006171 TOPRIM domain TSH58p_28825 2002c361037d5cccdc128dfa0ab95104 187 PIRSF PIRSF000239 1 187 2.9E-53 T 14-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TSH58p_28825 2002c361037d5cccdc128dfa0ab95104 187 Pfam PF00578 AhpC/TSA family 6 132 6.0E-34 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TSH58p_28825 2002c361037d5cccdc128dfa0ab95104 187 Gene3D G3DSA:3.40.30.10 1 186 5.1E-61 T 14-10-2018 TSH58p_28825 2002c361037d5cccdc128dfa0ab95104 187 SUPERFAMILY SSF52833 1 186 3.37E-57 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_28825 2002c361037d5cccdc128dfa0ab95104 187 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 187 1.9E-104 T 14-10-2018 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TSH58p_28825 2002c361037d5cccdc128dfa0ab95104 187 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 156 181 8.0E-7 T 14-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TSH58p_12695 2b8b1b7ca577847e6ee1bc72472f59fc 410 SUPERFAMILY SSF53218 197 325 5.1E-19 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSH58p_12695 2b8b1b7ca577847e6ee1bc72472f59fc 410 Gene3D G3DSA:3.90.105.10 65 192 8.1E-46 T 14-10-2018 TSH58p_12695 2b8b1b7ca577847e6ee1bc72472f59fc 410 Gene3D G3DSA:2.170.190.11 81 159 8.1E-46 T 14-10-2018 TSH58p_12695 2b8b1b7ca577847e6ee1bc72472f59fc 410 Gene3D G3DSA:3.40.980.10 193 322 8.1E-46 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSH58p_12695 2b8b1b7ca577847e6ee1bc72472f59fc 410 SMART SM00852 187 323 4.0E-6 T 14-10-2018 IPR001453 MoaB/Mog domain TSH58p_12695 2b8b1b7ca577847e6ee1bc72472f59fc 410 Pfam PF00994 Probable molybdopterin binding domain 210 317 1.9E-9 T 14-10-2018 IPR001453 MoaB/Mog domain TSH58p_12695 2b8b1b7ca577847e6ee1bc72472f59fc 410 SUPERFAMILY SSF63867 334 406 4.58E-10 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_12695 2b8b1b7ca577847e6ee1bc72472f59fc 410 Pfam PF03453 MoeA N-terminal region (domain I and II) 60 185 3.8E-27 T 14-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_12695 2b8b1b7ca577847e6ee1bc72472f59fc 410 Gene3D G3DSA:2.40.340.10 335 406 6.4E-10 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_12695 2b8b1b7ca577847e6ee1bc72472f59fc 410 SUPERFAMILY SSF63882 60 191 9.55E-31 T 14-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_05160 d5affdac9732aca3f1016a5a3a625519 425 TIGRFAM TIGR03253 oxalate_frc: formyl-CoA transferase 3 414 7.9E-224 T 14-10-2018 IPR017659 Formyl-CoA:oxalate CoA-transferase GO:0033608 MetaCyc: PWY-6695 TSH58p_05160 d5affdac9732aca3f1016a5a3a625519 425 SUPERFAMILY SSF89796 3 414 8.89E-125 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily TSH58p_05160 d5affdac9732aca3f1016a5a3a625519 425 Hamap MF_00742 Formyl-CoA:oxalate CoA-transferase [frc]. 1 415 66.301 T 14-10-2018 IPR017659 Formyl-CoA:oxalate CoA-transferase GO:0033608 MetaCyc: PWY-6695 TSH58p_05160 d5affdac9732aca3f1016a5a3a625519 425 Gene3D G3DSA:3.30.1540.10 241 337 2.4E-156 T 14-10-2018 TSH58p_05160 d5affdac9732aca3f1016a5a3a625519 425 Gene3D G3DSA:3.40.50.10540 5 406 2.4E-156 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily TSH58p_05160 d5affdac9732aca3f1016a5a3a625519 425 Pfam PF02515 CoA-transferase family III 5 391 2.0E-103 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 TSH58p_09930 0e3c3bad7286215b7e16db2db5ba91e4 646 Pfam PF13193 AMP-binding enzyme C-terminal domain 528 606 1.6E-25 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSH58p_09930 0e3c3bad7286215b7e16db2db5ba91e4 646 SUPERFAMILY SSF56801 13 638 2.09E-188 T 14-10-2018 TSH58p_09930 0e3c3bad7286215b7e16db2db5ba91e4 646 Pfam PF00501 AMP-binding enzyme 82 519 1.8E-95 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_09930 0e3c3bad7286215b7e16db2db5ba91e4 646 Gene3D G3DSA:3.30.300.30 515 646 2.6E-31 T 14-10-2018 TSH58p_09930 0e3c3bad7286215b7e16db2db5ba91e4 646 ProSitePatterns PS00455 Putative AMP-binding domain signature. 258 269 - T 14-10-2018 IPR020845 AMP-binding, conserved site TSH58p_09930 0e3c3bad7286215b7e16db2db5ba91e4 646 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 2 642 54.346 T 14-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 TSH58p_09930 0e3c3bad7286215b7e16db2db5ba91e4 646 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 24 80 5.3E-22 T 14-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 TSH58p_09930 0e3c3bad7286215b7e16db2db5ba91e4 646 Gene3D G3DSA:3.40.50.12780 52 512 1.6E-109 T 14-10-2018 TSH58p_09930 0e3c3bad7286215b7e16db2db5ba91e4 646 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 21 640 0.0 T 14-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 TSH58p_00700 7acf5520cbf05577ca3cfe920ae0ded9 501 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 362 382 - T 14-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 TSH58p_00700 7acf5520cbf05577ca3cfe920ae0ded9 501 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 6 497 1.1E-208 T 14-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 TSH58p_00700 7acf5520cbf05577ca3cfe920ae0ded9 501 PIRSF PIRSF000538 5 500 3.7E-175 T 14-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 TSH58p_00700 7acf5520cbf05577ca3cfe920ae0ded9 501 SUPERFAMILY SSF53067 255 499 9.32E-80 T 14-10-2018 TSH58p_00700 7acf5520cbf05577ca3cfe920ae0ded9 501 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 262 454 1.9E-54 T 14-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 TSH58p_00700 7acf5520cbf05577ca3cfe920ae0ded9 501 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 252 6.0E-77 T 14-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 TSH58p_00700 7acf5520cbf05577ca3cfe920ae0ded9 501 Gene3D G3DSA:3.30.420.40 5 253 2.6E-107 T 14-10-2018 TSH58p_00700 7acf5520cbf05577ca3cfe920ae0ded9 501 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 136 148 - T 14-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 TSH58p_00700 7acf5520cbf05577ca3cfe920ae0ded9 501 Gene3D G3DSA:3.30.420.40 254 501 6.4E-85 T 14-10-2018 TSH58p_00700 7acf5520cbf05577ca3cfe920ae0ded9 501 Hamap MF_00186 Glycerol kinase [glpK]. 4 501 54.811 T 14-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 TSH58p_00700 7acf5520cbf05577ca3cfe920ae0ded9 501 SUPERFAMILY SSF53067 6 255 3.71E-95 T 14-10-2018 TSH58p_15245 d485b32494d199dc9eb648a54c832f75 120 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 5 120 7.7E-44 T 14-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_15245 d485b32494d199dc9eb648a54c832f75 120 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 3 120 29.212 T 14-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15245 d485b32494d199dc9eb648a54c832f75 120 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 5 120 2.8E-41 T 14-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15245 d485b32494d199dc9eb648a54c832f75 120 SUPERFAMILY SSF53137 5 118 1.53E-54 T 14-10-2018 TSH58p_15245 d485b32494d199dc9eb648a54c832f75 120 Gene3D G3DSA:3.30.420.100 3 120 2.2E-47 T 14-10-2018 TSH58p_13540 1e68dd7c02180d725e409989dd4332cb 107 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 3 103 3.1E-30 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family TSH58p_13540 1e68dd7c02180d725e409989dd4332cb 107 Gene3D G3DSA:3.30.1310.10 1 107 7.1E-40 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily TSH58p_13540 1e68dd7c02180d725e409989dd4332cb 107 SUPERFAMILY SSF82607 8 101 2.49E-32 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily TSH58p_13540 1e68dd7c02180d725e409989dd4332cb 107 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 2 96 22.105 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family TSH58p_13540 1e68dd7c02180d725e409989dd4332cb 107 PIRSF PIRSF004555 1 107 3.0E-38 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family TSH58p_13540 1e68dd7c02180d725e409989dd4332cb 107 Pfam PF02575 YbaB/EbfC DNA-binding family 8 97 9.8E-33 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family TSH58p_23270 693f109ec91d1424e9f5cd6c2f679cc7 243 Pfam PF04402 Protein of unknown function (DUF541) 39 207 9.7E-18 T 14-10-2018 IPR007497 Protein of unknown function DUF541 TSH58p_23270 693f109ec91d1424e9f5cd6c2f679cc7 243 PIRSF PIRSF029033 2 243 1.8E-55 T 14-10-2018 IPR016907 Uncharacterised conserved protein UCP029033, periplasmic protein TSH58p_11475 f93dba82855f67a7c7deec4435e7e7c0 184 Pfam PF06347 Bacterial SH3 domain 128 176 1.5E-11 T 14-10-2018 IPR010466 Protein of unknown function DUF1058 TSH58p_11475 f93dba82855f67a7c7deec4435e7e7c0 184 Pfam PF06347 Bacterial SH3 domain 60 115 2.7E-16 T 14-10-2018 IPR010466 Protein of unknown function DUF1058 TSH58p_11475 f93dba82855f67a7c7deec4435e7e7c0 184 Gene3D G3DSA:2.30.30.40 59 114 1.3E-6 T 14-10-2018 TSH58p_11475 f93dba82855f67a7c7deec4435e7e7c0 184 Gene3D G3DSA:2.30.30.40 115 173 1.7E-5 T 14-10-2018 TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 Pfam PF00512 His Kinase A (phospho-acceptor) domain 609 674 1.1E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 Pfam PF08448 PAS fold 356 463 5.2E-8 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 SUPERFAMILY SSF47384 595 675 1.75E-19 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 Gene3D G3DSA:1.20.120.160 994 1100 1.7E-15 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 Gene3D G3DSA:3.30.565.10 673 837 1.0E-47 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 721 834 9.6E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 Gene3D G3DSA:3.30.450.20 199 287 1.8E-20 T 14-10-2018 TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 SUPERFAMILY SSF47226 993 1099 1.27E-15 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 Gene3D G3DSA:1.10.287.130 588 672 1.6E-25 T 14-10-2018 TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 SUPERFAMILY SSF55785 458 586 5.58E-27 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 Pfam PF00989 PAS fold 474 585 3.3E-15 T 14-10-2018 IPR013767 PAS fold GO:0006355 TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 SUPERFAMILY SSF55874 663 834 1.24E-43 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 Gene3D G3DSA:3.40.50.2300 843 979 7.1E-39 T 14-10-2018 TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 PRINTS PR00344 Bacterial sensor protein C-terminal signature 763 777 6.2E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 PRINTS PR00344 Bacterial sensor protein C-terminal signature 798 816 6.2E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 PRINTS PR00344 Bacterial sensor protein C-terminal signature 822 835 6.2E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 PRINTS PR00344 Bacterial sensor protein C-terminal signature 781 791 6.2E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 SMART SM00448 859 975 2.1E-37 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 SMART SM00388 609 674 6.7E-22 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 SMART SM00091 346 412 75.0 T 14-10-2018 IPR000014 PAS domain TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 SMART SM00091 473 539 1.4E-10 T 14-10-2018 IPR000014 PAS domain TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 SMART SM00086 549 589 6.9 T 14-10-2018 IPR001610 PAC motif TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 SMART SM00086 419 461 0.0036 T 14-10-2018 IPR001610 PAC motif TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 Pfam PF00072 Response regulator receiver domain 861 975 1.0E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 Gene3D G3DSA:3.30.450.20 50 196 9.5E-33 T 14-10-2018 TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 Gene3D G3DSA:3.30.450.20 331 470 1.2E-20 T 14-10-2018 TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 Gene3D G3DSA:3.30.450.20 471 587 1.1E-27 T 14-10-2018 TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 343 468 1.2E-6 T 14-10-2018 IPR000014 PAS domain TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 470 596 1.0E-27 T 14-10-2018 IPR000014 PAS domain TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 Pfam PF01627 Hpt domain 1023 1099 9.6E-8 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 SMART SM00387 721 838 2.8E-38 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 SUPERFAMILY SSF55785 336 459 6.63E-14 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_02405 57248f6ad35c46d981413de55f621bea 1107 SUPERFAMILY SSF52172 857 980 6.69E-37 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_22150 cca9dfd61f82247d437c95d5783c08df 478 PIRSF PIRSF006603 38 473 2.8E-50 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TSH58p_22150 cca9dfd61f82247d437c95d5783c08df 478 TIGRFAM TIGR00797 matE: MATE efflux family protein 47 445 1.5E-55 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TSH58p_22150 cca9dfd61f82247d437c95d5783c08df 478 Pfam PF01554 MatE 278 432 3.7E-22 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TSH58p_22150 cca9dfd61f82247d437c95d5783c08df 478 Pfam PF01554 MatE 47 206 1.4E-21 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TSH58p_10390 912275a48e19470dab0cf390d05162f9 391 Pfam PF10442 FIST C domain 238 376 2.1E-26 T 14-10-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 TSH58p_10390 912275a48e19470dab0cf390d05162f9 391 Pfam PF08495 FIST N domain 44 236 4.9E-26 T 14-10-2018 IPR013702 FIST domain, N-terminal TSH58p_10390 912275a48e19470dab0cf390d05162f9 391 SMART SM00897 43 237 2.5E-24 T 14-10-2018 IPR013702 FIST domain, N-terminal TSH58p_10390 912275a48e19470dab0cf390d05162f9 391 SMART SM01204 238 378 7.6E-38 T 14-10-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 TSH58p_10390 912275a48e19470dab0cf390d05162f9 391 PIRSF PIRSF018953 7 391 8.3E-52 T 14-10-2018 IPR016741 Uncharacterised conserved protein UCP018953 TSH58p_10035 39097e2179a94ac416868454a4ab83ed 464 SUPERFAMILY SSF58104 128 382 1.7E-32 T 14-10-2018 TSH58p_10035 39097e2179a94ac416868454a4ab83ed 464 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 280 380 8.7E-22 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_10035 39097e2179a94ac416868454a4ab83ed 464 Gene3D G3DSA:1.10.287.950 158 418 2.5E-29 T 14-10-2018 TSH58p_10035 39097e2179a94ac416868454a4ab83ed 464 SMART SM00283 204 447 2.1E-4 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_02835 4e3eb687831f5a5d4a51807827746f97 532 Gene3D G3DSA:3.40.50.720 194 323 5.2E-14 T 14-10-2018 TSH58p_02835 4e3eb687831f5a5d4a51807827746f97 532 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 95 532 4.6E-125 T 14-10-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase TSH58p_02835 4e3eb687831f5a5d4a51807827746f97 532 Pfam PF13727 CoA-binding domain 109 302 1.3E-22 T 14-10-2018 TSH58p_02835 4e3eb687831f5a5d4a51807827746f97 532 Pfam PF02397 Bacterial sugar transferase 338 524 5.7E-65 T 14-10-2018 IPR003362 Bacterial sugar transferase TSH58p_02835 4e3eb687831f5a5d4a51807827746f97 532 TIGRFAM TIGR03023 WcaJ_sugtrans: undecaprenyl-phosphate glucose phosphotransferase 97 532 1.5E-130 T 14-10-2018 IPR017473 Undecaprenyl-phosphate glucose phosphotransferase, WcaJ MetaCyc: PWY-6655|MetaCyc: PWY-6658 TSH58p_07685 8a40a20200f4610c4cd7db264666b9a1 68 Pfam PF05082 Rop-like 2 65 5.3E-30 T 14-10-2018 IPR007774 Putative nitrogen fixation protein TSH58p_07685 8a40a20200f4610c4cd7db264666b9a1 68 PIRSF PIRSF037676 1 67 1.0E-26 T 14-10-2018 IPR007774 Putative nitrogen fixation protein TSH58p_07685 8a40a20200f4610c4cd7db264666b9a1 68 Gene3D G3DSA:1.10.287.660 1 68 1.7E-28 T 14-10-2018 IPR029012 Helix hairpin bin domain superfamily TSH58p_04965 81fd8961b1001e42162fbabcb630b105 139 Pfam PF11127 Protein of unknown function (DUF2892) 24 79 4.5E-11 T 14-10-2018 IPR021309 Protein of unknown function DUF2892 TSH58p_03945 745a3a8f879b4b45591e71a1801d6303 215 SMART SM00448 1 115 4.8E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_03945 745a3a8f879b4b45591e71a1801d6303 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 209 1.1E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_03945 745a3a8f879b4b45591e71a1801d6303 215 SUPERFAMILY SSF46894 146 211 8.16E-20 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_03945 745a3a8f879b4b45591e71a1801d6303 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 1.0E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_03945 745a3a8f879b4b45591e71a1801d6303 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 1.0E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_03945 745a3a8f879b4b45591e71a1801d6303 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 1.0E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_03945 745a3a8f879b4b45591e71a1801d6303 215 Pfam PF00072 Response regulator receiver domain 3 115 1.4E-18 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_03945 745a3a8f879b4b45591e71a1801d6303 215 Gene3D G3DSA:3.40.50.12740 1 214 6.0E-51 T 14-10-2018 TSH58p_03945 745a3a8f879b4b45591e71a1801d6303 215 SMART SM00421 153 210 1.5E-25 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_03945 745a3a8f879b4b45591e71a1801d6303 215 SUPERFAMILY SSF52172 1 127 5.41E-26 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_27230 ca39ea60effc26fb69b8754fba1f06a1 165 TIGRFAM TIGR01935 NOT-MenG: RraA family 7 155 1.1E-62 T 14-10-2018 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 TSH58p_27230 ca39ea60effc26fb69b8754fba1f06a1 165 SUPERFAMILY SSF89562 6 159 1.7E-48 T 14-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily TSH58p_27230 ca39ea60effc26fb69b8754fba1f06a1 165 Gene3D G3DSA:3.50.30.40 2 163 2.5E-61 T 14-10-2018 TSH58p_27230 ca39ea60effc26fb69b8754fba1f06a1 165 Pfam PF03737 Aldolase/RraA 7 155 2.9E-44 T 14-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein TSH58p_25990 7b3f51f95c80db4ed9a8ef28ee6b4fce 695 SUPERFAMILY SSF158472 211 255 5.23E-7 T 14-10-2018 TSH58p_25990 7b3f51f95c80db4ed9a8ef28ee6b4fce 695 SUPERFAMILY SSF103190 82 175 3.65E-10 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily TSH58p_25990 7b3f51f95c80db4ed9a8ef28ee6b4fce 695 Pfam PF00672 HAMP domain 207 255 2.8E-6 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_25990 7b3f51f95c80db4ed9a8ef28ee6b4fce 695 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 401 430 3.0E-50 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_25990 7b3f51f95c80db4ed9a8ef28ee6b4fce 695 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 478 505 3.0E-50 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_25990 7b3f51f95c80db4ed9a8ef28ee6b4fce 695 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 507 536 3.0E-50 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_25990 7b3f51f95c80db4ed9a8ef28ee6b4fce 695 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 555 584 3.0E-50 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_25990 7b3f51f95c80db4ed9a8ef28ee6b4fce 695 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 439 595 3.2E-51 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_25990 7b3f51f95c80db4ed9a8ef28ee6b4fce 695 Gene3D G3DSA:1.10.287.950 328 629 2.9E-81 T 14-10-2018 TSH58p_25990 7b3f51f95c80db4ed9a8ef28ee6b4fce 695 Gene3D G3DSA:1.10.8.500 213 261 3.8E-12 T 14-10-2018 TSH58p_25990 7b3f51f95c80db4ed9a8ef28ee6b4fce 695 SUPERFAMILY SSF58104 347 628 6.19E-71 T 14-10-2018 TSH58p_25990 7b3f51f95c80db4ed9a8ef28ee6b4fce 695 SMART SM00283 380 627 1.2E-97 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_25990 7b3f51f95c80db4ed9a8ef28ee6b4fce 695 Pfam PF17202 Single cache domain 3 77 181 5.8E-33 T 14-10-2018 IPR033463 Single cache domain 3 TSH58p_25990 7b3f51f95c80db4ed9a8ef28ee6b4fce 695 SMART SM00304 207 260 9.3E-6 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_25990 7b3f51f95c80db4ed9a8ef28ee6b4fce 695 SMART SM00304 327 379 0.15 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_00795 54bc693dae60ae141270769aa4fe6793 664 Pfam PF17202 Single cache domain 3 79 181 8.9E-34 T 14-10-2018 IPR033463 Single cache domain 3 TSH58p_00795 54bc693dae60ae141270769aa4fe6793 664 SMART SM00283 299 553 7.4E-45 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_00795 54bc693dae60ae141270769aa4fe6793 664 Gene3D G3DSA:1.10.287.950 267 562 7.3E-53 T 14-10-2018 TSH58p_00795 54bc693dae60ae141270769aa4fe6793 664 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 365 520 4.4E-30 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_00795 54bc693dae60ae141270769aa4fe6793 664 SUPERFAMILY SSF103190 82 174 3.66E-11 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily TSH58p_00795 54bc693dae60ae141270769aa4fe6793 664 SUPERFAMILY SSF141371 560 613 9.02E-5 T 14-10-2018 TSH58p_00795 54bc693dae60ae141270769aa4fe6793 664 SMART SM00304 209 262 0.026 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_00795 54bc693dae60ae141270769aa4fe6793 664 SMART SM00304 494 550 28.0 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_00795 54bc693dae60ae141270769aa4fe6793 664 SUPERFAMILY SSF58104 237 548 3.14E-57 T 14-10-2018 TSH58p_00795 54bc693dae60ae141270769aa4fe6793 664 Gene3D G3DSA:1.10.8.500 213 258 9.3E-11 T 14-10-2018 TSH58p_00795 54bc693dae60ae141270769aa4fe6793 664 Pfam PF07238 PilZ domain 561 644 1.4E-8 T 14-10-2018 IPR009875 PilZ domain GO:0035438 TSH58p_20245 58031333760777f174b3f9963682c744 342 Gene3D G3DSA:1.10.220.30 98 198 3.8E-22 T 14-10-2018 TSH58p_20245 58031333760777f174b3f9963682c744 342 Pfam PF14841 FliG middle domain 125 195 5.8E-21 T 14-10-2018 IPR032779 Flagellar motor switch protein FliG, middle domain TSH58p_20245 58031333760777f174b3f9963682c744 342 PRINTS PR00954 Flagellar motor switch protein FliG signature 43 69 1.3E-45 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 TSH58p_20245 58031333760777f174b3f9963682c744 342 PRINTS PR00954 Flagellar motor switch protein FliG signature 202 227 1.3E-45 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 TSH58p_20245 58031333760777f174b3f9963682c744 342 PRINTS PR00954 Flagellar motor switch protein FliG signature 255 275 1.3E-45 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 TSH58p_20245 58031333760777f174b3f9963682c744 342 PRINTS PR00954 Flagellar motor switch protein FliG signature 279 305 1.3E-45 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 TSH58p_20245 58031333760777f174b3f9963682c744 342 PRINTS PR00954 Flagellar motor switch protein FliG signature 233 253 1.3E-45 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 TSH58p_20245 58031333760777f174b3f9963682c744 342 PRINTS PR00954 Flagellar motor switch protein FliG signature 14 30 1.3E-45 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 TSH58p_20245 58031333760777f174b3f9963682c744 342 PRINTS PR00954 Flagellar motor switch protein FliG signature 122 145 1.3E-45 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 TSH58p_20245 58031333760777f174b3f9963682c744 342 Gene3D G3DSA:1.10.220.30 8 92 1.4E-14 T 14-10-2018 TSH58p_20245 58031333760777f174b3f9963682c744 342 Pfam PF01706 FliG C-terminal domain 225 331 1.5E-33 T 14-10-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal TSH58p_20245 58031333760777f174b3f9963682c744 342 SUPERFAMILY SSF48029 10 121 6.02E-18 T 14-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical TSH58p_20245 58031333760777f174b3f9963682c744 342 SUPERFAMILY SSF48029 124 331 6.8E-56 T 14-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical TSH58p_20245 58031333760777f174b3f9963682c744 342 Pfam PF14842 FliG N-terminal domain 14 115 1.1E-22 T 14-10-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain TSH58p_20245 58031333760777f174b3f9963682c744 342 Gene3D G3DSA:1.10.220.30 203 341 4.3E-38 T 14-10-2018 TSH58p_01425 385bd2e457e797f9b4c73b6ff5dd484d 504 Gene3D G3DSA:3.30.300.310 397 499 1.2E-33 T 14-10-2018 TSH58p_01425 385bd2e457e797f9b4c73b6ff5dd484d 504 SUPERFAMILY SSF56801 4 497 5.49E-149 T 14-10-2018 TSH58p_01425 385bd2e457e797f9b4c73b6ff5dd484d 504 Pfam PF00501 AMP-binding enzyme 12 401 7.7E-99 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_01425 385bd2e457e797f9b4c73b6ff5dd484d 504 Pfam PF13193 AMP-binding enzyme C-terminal domain 410 485 2.3E-19 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSH58p_01425 385bd2e457e797f9b4c73b6ff5dd484d 504 Gene3D G3DSA:3.40.50.12780 1 394 3.3E-111 T 14-10-2018 TSH58p_02505 59c9c2a4feb813648e2fb005aad2fe94 241 Pfam PF07277 SapC 19 232 8.8E-70 T 14-10-2018 IPR010836 SapC TSH58p_31835 1cb3c08c1d1bf80290e321783fa005b4 764 Pfam PF13450 NAD(P)-binding Rossmann-like domain 8 78 1.7E-13 T 14-10-2018 TSH58p_31835 1cb3c08c1d1bf80290e321783fa005b4 764 Gene3D G3DSA:3.50.50.60 2 104 8.5E-7 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_31835 1cb3c08c1d1bf80290e321783fa005b4 764 SUPERFAMILY SSF51905 1 748 2.46E-14 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_05885 6a03af8c5259158234857542043bd32c 690 Gene3D G3DSA:3.30.70.20 125 204 1.0E-6 T 14-10-2018 TSH58p_05885 6a03af8c5259158234857542043bd32c 690 SMART SM00929 83 123 6.4E-22 T 14-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05885 6a03af8c5259158234857542043bd32c 690 Pfam PF09326 NADH-ubiquinone oxidoreductase subunit G, C-terminal 635 671 2.2E-14 T 14-10-2018 IPR015405 NADH-quinone oxidoreductase, chain G, C-terminal GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05885 6a03af8c5259158234857542043bd32c 690 Gene3D G3DSA:3.10.20.740 1 123 1.2E-43 T 14-10-2018 TSH58p_05885 6a03af8c5259158234857542043bd32c 690 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 145 155 - T 14-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05885 6a03af8c5259158234857542043bd32c 690 SUPERFAMILY SSF54862 75 211 1.26E-38 T 14-10-2018 TSH58p_05885 6a03af8c5259158234857542043bd32c 690 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 4 596 1.8E-229 T 14-10-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05885 6a03af8c5259158234857542043bd32c 690 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 98 110 - T 14-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05885 6a03af8c5259158234857542043bd32c 690 Gene3D G3DSA:3.40.50.740 277 345 3.9E-10 T 14-10-2018 TSH58p_05885 6a03af8c5259158234857542043bd32c 690 SUPERFAMILY SSF53706 213 628 7.85E-107 T 14-10-2018 TSH58p_05885 6a03af8c5259158234857542043bd32c 690 Gene3D G3DSA:3.40.228.10 346 399 3.9E-10 T 14-10-2018 TSH58p_05885 6a03af8c5259158234857542043bd32c 690 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 3 76 4.6E-18 T 14-10-2018 TSH58p_05885 6a03af8c5259158234857542043bd32c 690 Gene3D G3DSA:3.40.50.740 420 630 4.2E-20 T 14-10-2018 TSH58p_05885 6a03af8c5259158234857542043bd32c 690 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 83 120 9.0E-18 T 14-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05885 6a03af8c5259158234857542043bd32c 690 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 14-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05885 6a03af8c5259158234857542043bd32c 690 SUPERFAMILY SSF54292 1 74 5.91E-21 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TSH58p_05885 6a03af8c5259158234857542043bd32c 690 Pfam PF00384 Molybdopterin oxidoreductase 271 598 1.2E-74 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_16240 8f147a8b2d1467a5ed9572e2a0da3f5b 335 SUPERFAMILY SSF51735 1 172 1.23E-64 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_16240 8f147a8b2d1467a5ed9572e2a0da3f5b 335 PIRSF PIRSF000149 1 335 5.5E-140 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_16240 8f147a8b2d1467a5ed9572e2a0da3f5b 335 Gene3D G3DSA:3.40.50.720 4 326 9.9E-153 T 14-10-2018 TSH58p_16240 8f147a8b2d1467a5ed9572e2a0da3f5b 335 Gene3D G3DSA:3.30.360.10 152 316 9.9E-153 T 14-10-2018 TSH58p_16240 8f147a8b2d1467a5ed9572e2a0da3f5b 335 SUPERFAMILY SSF55347 153 315 1.88E-69 T 14-10-2018 TSH58p_16240 8f147a8b2d1467a5ed9572e2a0da3f5b 335 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 104 8.8E-40 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_16240 8f147a8b2d1467a5ed9572e2a0da3f5b 335 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 3.9E-133 T 14-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_16240 8f147a8b2d1467a5ed9572e2a0da3f5b 335 SMART SM00846 3 153 1.8E-99 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_16240 8f147a8b2d1467a5ed9572e2a0da3f5b 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 111 124 4.2E-38 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_16240 8f147a8b2d1467a5ed9572e2a0da3f5b 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 270 285 4.2E-38 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_16240 8f147a8b2d1467a5ed9572e2a0da3f5b 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 4.2E-38 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_16240 8f147a8b2d1467a5ed9572e2a0da3f5b 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 147 165 4.2E-38 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_16240 8f147a8b2d1467a5ed9572e2a0da3f5b 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 174 190 4.2E-38 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_16240 8f147a8b2d1467a5ed9572e2a0da3f5b 335 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 158 314 3.0E-65 T 14-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_16240 8f147a8b2d1467a5ed9572e2a0da3f5b 335 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 151 158 - T 14-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_17260 3461a849df841e8fdccfe373a9583ea8 195 Gene3D G3DSA:2.40.30.20 100 195 2.2E-38 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSH58p_17260 3461a849df841e8fdccfe373a9583ea8 195 SUPERFAMILY SSF63380 1 91 8.25E-24 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TSH58p_17260 3461a849df841e8fdccfe373a9583ea8 195 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 191 7.6E-62 T 14-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TSH58p_17260 3461a849df841e8fdccfe373a9583ea8 195 Gene3D G3DSA:2.40.30.20 1 87 3.3E-26 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSH58p_17260 3461a849df841e8fdccfe373a9583ea8 195 PIRSF PIRSF000498 1 195 2.0E-75 T 14-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TSH58p_17260 3461a849df841e8fdccfe373a9583ea8 195 SUPERFAMILY SSF63380 92 191 1.87E-35 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TSH58p_17260 3461a849df841e8fdccfe373a9583ea8 195 Pfam PF00677 Lumazine binding domain 3 85 3.5E-22 T 14-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TSH58p_17260 3461a849df841e8fdccfe373a9583ea8 195 Pfam PF00677 Lumazine binding domain 98 182 2.7E-27 T 14-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TSH58p_04975 422a740ca59de0c1c0fe4b001ecdcb9c 212 SUPERFAMILY SSF52540 4 203 1.1E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_04975 422a740ca59de0c1c0fe4b001ecdcb9c 212 PIRSF PIRSF005624 6 207 7.8E-49 T 14-10-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 TSH58p_04975 422a740ca59de0c1c0fe4b001ecdcb9c 212 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 15 185 2.4E-37 T 14-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain TSH58p_04975 422a740ca59de0c1c0fe4b001ecdcb9c 212 Hamap MF_01389 Urease accessory protein UreG [ureG]. 11 209 47.665 T 14-10-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 TSH58p_04975 422a740ca59de0c1c0fe4b001ecdcb9c 212 Gene3D G3DSA:3.40.50.300 13 206 4.3E-50 T 14-10-2018 TSH58p_04975 422a740ca59de0c1c0fe4b001ecdcb9c 212 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 13 204 8.9E-105 T 14-10-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 TSH58p_28125 1f51a4c926dc791fd58becd2dc8c920b 310 SUPERFAMILY SSF103481 78 160 3.53E-8 T 14-10-2018 TSH58p_28125 1f51a4c926dc791fd58becd2dc8c920b 310 SUPERFAMILY SSF103481 207 303 1.7E-6 T 14-10-2018 TSH58p_28125 1f51a4c926dc791fd58becd2dc8c920b 310 Pfam PF00892 EamA-like transporter family 171 302 8.5E-12 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_28125 1f51a4c926dc791fd58becd2dc8c920b 310 Pfam PF00892 EamA-like transporter family 29 157 4.2E-11 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_09330 d5ef5066a869ec535cacbe6736b8559f 131 Gene3D G3DSA:1.20.1300.10 14 127 2.2E-27 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_09330 d5ef5066a869ec535cacbe6736b8559f 131 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 9 116 3.3E-17 T 14-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_09330 d5ef5066a869ec535cacbe6736b8559f 131 SUPERFAMILY SSF81343 16 127 6.7E-29 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_09330 d5ef5066a869ec535cacbe6736b8559f 131 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 21 124 2.4E-25 T 14-10-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 TSH58p_00165 d2a1f79c186e42d544bb384f9235c89f 239 Pfam PF04397 LytTr DNA-binding domain 143 236 7.2E-18 T 14-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 TSH58p_00165 d2a1f79c186e42d544bb384f9235c89f 239 SMART SM00448 2 112 2.6E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_00165 d2a1f79c186e42d544bb384f9235c89f 239 SUPERFAMILY SSF52172 1 122 1.07E-34 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_00165 d2a1f79c186e42d544bb384f9235c89f 239 Gene3D G3DSA:2.40.50.1020 138 237 1.7E-8 T 14-10-2018 TSH58p_00165 d2a1f79c186e42d544bb384f9235c89f 239 SMART SM00850 142 237 3.5E-22 T 14-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 TSH58p_00165 d2a1f79c186e42d544bb384f9235c89f 239 Gene3D G3DSA:3.40.50.2300 1 124 4.3E-33 T 14-10-2018 TSH58p_00165 d2a1f79c186e42d544bb384f9235c89f 239 Pfam PF00072 Response regulator receiver domain 4 112 8.7E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_13240 8b35fe5986793e9ef846e6c65828e21d 406 SMART SM00228 320 390 1.3E-10 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_13240 8b35fe5986793e9ef846e6c65828e21d 406 SUPERFAMILY SSF50156 319 395 2.76E-15 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 TSH58p_13240 8b35fe5986793e9ef846e6c65828e21d 406 SUPERFAMILY SSF159501 50 306 1.83E-67 T 14-10-2018 TSH58p_13240 8b35fe5986793e9ef846e6c65828e21d 406 Pfam PF04187 Haem-binding uptake, Tiki superfamily, ChaN 68 274 5.5E-65 T 14-10-2018 IPR007314 Haem-binding uptake, Tiki superfamily, ChaN TSH58p_13240 8b35fe5986793e9ef846e6c65828e21d 406 Pfam PF13180 PDZ domain 320 394 1.6E-9 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_13240 8b35fe5986793e9ef846e6c65828e21d 406 Gene3D G3DSA:1.10.8.760 173 238 4.4E-27 T 14-10-2018 TSH58p_13240 8b35fe5986793e9ef846e6c65828e21d 406 Gene3D G3DSA:2.30.42.10 311 401 7.8E-16 T 14-10-2018 TSH58p_13240 8b35fe5986793e9ef846e6c65828e21d 406 Gene3D G3DSA:3.40.50.11550 61 286 4.4E-27 T 14-10-2018 TSH58p_22395 1656d9712354b2ced16e114ece851cd3 311 SUPERFAMILY SSF48576 19 307 6.76E-65 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily TSH58p_22395 1656d9712354b2ced16e114ece851cd3 311 Gene3D G3DSA:1.10.600.10 8 284 1.0E-63 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily TSH58p_22395 1656d9712354b2ced16e114ece851cd3 311 Pfam PF00494 Squalene/phytoene synthase 27 294 9.4E-59 T 14-10-2018 TSH58p_22395 1656d9712354b2ced16e114ece851cd3 311 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 178 203 - T 14-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TSH58p_11915 a51982ea123a20203be686cb2a8fc9ee 798 Gene3D G3DSA:3.30.56.10 5 181 1.7E-66 T 14-10-2018 TSH58p_11915 a51982ea123a20203be686cb2a8fc9ee 798 Pfam PF03484 tRNA synthetase B5 domain 404 470 9.9E-16 T 14-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TSH58p_11915 a51982ea123a20203be686cb2a8fc9ee 798 Gene3D G3DSA:3.30.70.380 705 798 2.3E-25 T 14-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 TSH58p_11915 a51982ea123a20203be686cb2a8fc9ee 798 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 791 42.375 T 14-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 TSH58p_11915 a51982ea123a20203be686cb2a8fc9ee 798 Gene3D G3DSA:3.50.40.10 199 392 3.5E-72 T 14-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 TSH58p_11915 a51982ea123a20203be686cb2a8fc9ee 798 Pfam PF01588 Putative tRNA binding domain 45 145 5.5E-24 T 14-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 TSH58p_11915 a51982ea123a20203be686cb2a8fc9ee 798 Pfam PF03483 B3/4 domain 212 384 1.3E-62 T 14-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 TSH58p_11915 a51982ea123a20203be686cb2a8fc9ee 798 SUPERFAMILY SSF50249 36 195 5.88E-44 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_11915 a51982ea123a20203be686cb2a8fc9ee 798 SMART SM00896 704 797 1.3E-41 T 14-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 TSH58p_11915 a51982ea123a20203be686cb2a8fc9ee 798 SUPERFAMILY SSF55681 466 687 6.96E-40 T 14-10-2018 TSH58p_11915 a51982ea123a20203be686cb2a8fc9ee 798 Gene3D G3DSA:3.30.56.10 400 475 4.6E-21 T 14-10-2018 TSH58p_11915 a51982ea123a20203be686cb2a8fc9ee 798 SMART SM00873 212 384 1.9E-84 T 14-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 TSH58p_11915 a51982ea123a20203be686cb2a8fc9ee 798 SUPERFAMILY SSF46955 401 474 4.94E-16 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily TSH58p_11915 a51982ea123a20203be686cb2a8fc9ee 798 Gene3D G3DSA:3.30.930.10 489 688 2.8E-40 T 14-10-2018 TSH58p_11915 a51982ea123a20203be686cb2a8fc9ee 798 SMART SM00874 400 470 1.1E-25 T 14-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TSH58p_11915 a51982ea123a20203be686cb2a8fc9ee 798 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 797 2.6E-216 T 14-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 TSH58p_11915 a51982ea123a20203be686cb2a8fc9ee 798 SUPERFAMILY SSF56037 197 395 5.49E-71 T 14-10-2018 TSH58p_11915 a51982ea123a20203be686cb2a8fc9ee 798 Gene3D G3DSA:2.40.50.140 39 154 1.7E-66 T 14-10-2018 TSH58p_11915 a51982ea123a20203be686cb2a8fc9ee 798 Pfam PF03147 Ferredoxin-fold anticodon binding domain 704 797 4.0E-26 T 14-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 TSH58p_11915 a51982ea123a20203be686cb2a8fc9ee 798 SUPERFAMILY SSF54991 701 797 9.15E-28 T 14-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 TSH58p_24735 73671097fc56d6c8f2fcd21ffa9b171f 418 SUPERFAMILY SSF50249 46 129 1.37E-11 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_24735 73671097fc56d6c8f2fcd21ffa9b171f 418 Pfam PF10150 Ribonuclease E/G family 125 394 2.0E-69 T 14-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 TSH58p_24735 73671097fc56d6c8f2fcd21ffa9b171f 418 Gene3D G3DSA:2.40.50.140 38 129 1.8E-19 T 14-10-2018 TSH58p_24735 73671097fc56d6c8f2fcd21ffa9b171f 418 SMART SM00316 44 123 1.6E-6 T 14-10-2018 IPR022967 RNA-binding domain, S1 TSH58p_03765 3d87bf35dd464ca06091a6f3241448c8 592 SUPERFAMILY SSF51206 447 571 1.31E-29 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like TSH58p_03765 3d87bf35dd464ca06091a6f3241448c8 592 Pfam PF00027 Cyclic nucleotide-binding domain 478 557 4.9E-18 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_03765 3d87bf35dd464ca06091a6f3241448c8 592 Pfam PF00999 Sodium/hydrogen exchanger family 14 397 8.5E-70 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TSH58p_03765 3d87bf35dd464ca06091a6f3241448c8 592 SMART SM00100 457 572 7.7E-21 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_03765 3d87bf35dd464ca06091a6f3241448c8 592 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 484 500 - T 14-10-2018 IPR018488 Cyclic nucleotide-binding, conserved site TSH58p_03765 3d87bf35dd464ca06091a6f3241448c8 592 Gene3D G3DSA:1.20.1530.20 6 410 2.5E-75 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily TSH58p_03765 3d87bf35dd464ca06091a6f3241448c8 592 Gene3D G3DSA:2.60.120.10 420 583 2.3E-31 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_25825 b4b34df06e6a89f1c79e76b17a1db4be 1515 Pfam PF01493 GXGXG motif 1270 1453 1.6E-75 T 14-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 TSH58p_25825 b4b34df06e6a89f1c79e76b17a1db4be 1515 Gene3D G3DSA:3.20.20.70 817 1229 3.5E-182 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_25825 b4b34df06e6a89f1c79e76b17a1db4be 1515 Gene3D G3DSA:3.20.20.70 459 816 4.0E-137 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_25825 b4b34df06e6a89f1c79e76b17a1db4be 1515 SUPERFAMILY SSF56235 37 457 2.55E-147 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_25825 b4b34df06e6a89f1c79e76b17a1db4be 1515 Pfam PF00310 Glutamine amidotransferases class-II 37 455 6.5E-156 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain TSH58p_25825 b4b34df06e6a89f1c79e76b17a1db4be 1515 Pfam PF01645 Conserved region in glutamate synthase 829 1192 4.3E-161 T 14-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 TSH58p_25825 b4b34df06e6a89f1c79e76b17a1db4be 1515 SUPERFAMILY SSF51395 461 1228 6.87E-259 T 14-10-2018 TSH58p_25825 b4b34df06e6a89f1c79e76b17a1db4be 1515 Gene3D G3DSA:2.160.20.60 1242 1515 8.3E-115 T 14-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 TSH58p_25825 b4b34df06e6a89f1c79e76b17a1db4be 1515 Pfam PF04898 Glutamate synthase central domain 485 767 8.0E-100 T 14-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 TSH58p_25825 b4b34df06e6a89f1c79e76b17a1db4be 1515 Gene3D G3DSA:3.60.20.10 37 458 1.6E-165 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_25825 b4b34df06e6a89f1c79e76b17a1db4be 1515 SUPERFAMILY SSF69336 1241 1504 7.46E-92 T 14-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 TSH58p_27395 4862bb8aa6890e8ec4717da0c6dae65e 206 Gene3D G3DSA:1.10.10.60 10 62 5.5E-20 T 14-10-2018 TSH58p_27395 4862bb8aa6890e8ec4717da0c6dae65e 206 SUPERFAMILY SSF48498 87 197 3.29E-9 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TSH58p_27395 4862bb8aa6890e8ec4717da0c6dae65e 206 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 150 204 4.9E-16 T 14-10-2018 IPR039536 Transcriptional regulator TetR, C-terminal, Proteobacteria type TSH58p_27395 4862bb8aa6890e8ec4717da0c6dae65e 206 Gene3D G3DSA:1.10.357.10 68 206 4.1E-38 T 14-10-2018 TSH58p_27395 4862bb8aa6890e8ec4717da0c6dae65e 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 2.2E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_27395 4862bb8aa6890e8ec4717da0c6dae65e 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 2.2E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_27395 4862bb8aa6890e8ec4717da0c6dae65e 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 62 9.0E-19 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_27395 4862bb8aa6890e8ec4717da0c6dae65e 206 SUPERFAMILY SSF46689 11 70 1.25E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_27395 4862bb8aa6890e8ec4717da0c6dae65e 206 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 60 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site TSH58p_12265 28ac2196eef98bda954eabebbe56aa54 459 SUPERFAMILY SSF47384 239 312 2.35E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_12265 28ac2196eef98bda954eabebbe56aa54 459 Gene3D G3DSA:1.10.287.130 199 309 6.9E-20 T 14-10-2018 TSH58p_12265 28ac2196eef98bda954eabebbe56aa54 459 SMART SM00387 352 459 2.2E-25 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_12265 28ac2196eef98bda954eabebbe56aa54 459 Gene3D G3DSA:3.30.565.10 318 459 1.2E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_12265 28ac2196eef98bda954eabebbe56aa54 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 400 8.9E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_12265 28ac2196eef98bda954eabebbe56aa54 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 458 8.9E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_12265 28ac2196eef98bda954eabebbe56aa54 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 414 8.9E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_12265 28ac2196eef98bda954eabebbe56aa54 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 439 8.9E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_12265 28ac2196eef98bda954eabebbe56aa54 459 SMART SM00388 255 313 1.0E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_12265 28ac2196eef98bda954eabebbe56aa54 459 Pfam PF00512 His Kinase A (phospho-acceptor) domain 256 311 2.1E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_12265 28ac2196eef98bda954eabebbe56aa54 459 SUPERFAMILY SSF55874 312 459 6.42E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_12265 28ac2196eef98bda954eabebbe56aa54 459 Pfam PF00672 HAMP domain 202 250 3.9E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_12265 28ac2196eef98bda954eabebbe56aa54 459 SMART SM00304 202 254 2.8E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_12265 28ac2196eef98bda954eabebbe56aa54 459 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 354 458 1.6E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_21700 bf5ba6df2c77109202c5d3e0ec2c9fd1 329 SUPERFAMILY SSF53335 61 197 7.07E-14 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_21700 bf5ba6df2c77109202c5d3e0ec2c9fd1 329 Gene3D G3DSA:3.40.50.150 19 221 3.2E-10 T 14-10-2018 TSH58p_21700 bf5ba6df2c77109202c5d3e0ec2c9fd1 329 Pfam PF09243 Mitochondrial small ribosomal subunit Rsm22 50 321 2.1E-97 T 14-10-2018 IPR015324 Ribosomal protein Rsm22-like GO:0006412|GO:0008168 TSH58p_27695 8ef30e3d1814d2a188e4bc942f915d2b 300 Gene3D G3DSA:3.40.190.290 92 291 1.3E-64 T 14-10-2018 TSH58p_27695 8ef30e3d1814d2a188e4bc942f915d2b 300 Gene3D G3DSA:1.10.10.10 3 91 4.2E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_27695 8ef30e3d1814d2a188e4bc942f915d2b 300 SUPERFAMILY SSF46785 4 87 1.36E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_27695 8ef30e3d1814d2a188e4bc942f915d2b 300 SUPERFAMILY SSF53850 89 296 1.7E-47 T 14-10-2018 TSH58p_27695 8ef30e3d1814d2a188e4bc942f915d2b 300 Pfam PF03466 LysR substrate binding domain 88 293 4.4E-47 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_27695 8ef30e3d1814d2a188e4bc942f915d2b 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.6E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_27695 8ef30e3d1814d2a188e4bc942f915d2b 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.6E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_27695 8ef30e3d1814d2a188e4bc942f915d2b 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.6E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_27695 8ef30e3d1814d2a188e4bc942f915d2b 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 63 5.6E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_07525 ad379046fbf413a8f08963b8350785f2 313 SUPERFAMILY SSF52540 3 228 1.04E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_07525 ad379046fbf413a8f08963b8350785f2 313 SMART SM00382 31 210 1.2E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_07525 ad379046fbf413a8f08963b8350785f2 313 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_07525 ad379046fbf413a8f08963b8350785f2 313 Gene3D G3DSA:3.40.50.300 1 231 6.7E-68 T 14-10-2018 TSH58p_07525 ad379046fbf413a8f08963b8350785f2 313 Pfam PF00005 ABC transporter 23 164 3.7E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_15150 bd5bbf6d90ed4817fcfb4de696c6e8d7 692 Pfam PF00009 Elongation factor Tu GTP binding domain 9 281 1.1E-68 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_15150 bd5bbf6d90ed4817fcfb4de696c6e8d7 692 SMART SM00838 600 687 1.1E-51 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like TSH58p_15150 bd5bbf6d90ed4817fcfb4de696c6e8d7 692 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 179 4.6E-34 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSH58p_15150 bd5bbf6d90ed4817fcfb4de696c6e8d7 692 Gene3D G3DSA:3.30.70.870 406 483 3.7E-33 T 14-10-2018 TSH58p_15150 bd5bbf6d90ed4817fcfb4de696c6e8d7 692 SUPERFAMILY SSF54980 402 480 5.4E-25 T 14-10-2018 IPR035647 EF-G domain III/V-like TSH58p_15150 bd5bbf6d90ed4817fcfb4de696c6e8d7 692 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.2E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_15150 bd5bbf6d90ed4817fcfb4de696c6e8d7 692 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.2E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_15150 bd5bbf6d90ed4817fcfb4de696c6e8d7 692 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.2E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_15150 bd5bbf6d90ed4817fcfb4de696c6e8d7 692 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.2E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_15150 bd5bbf6d90ed4817fcfb4de696c6e8d7 692 PRINTS PR00315 GTP-binding elongation factor signature 130 139 1.2E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_15150 bd5bbf6d90ed4817fcfb4de696c6e8d7 692 SUPERFAMILY SSF54980 603 687 1.06E-28 T 14-10-2018 IPR035647 EF-G domain III/V-like TSH58p_15150 bd5bbf6d90ed4817fcfb4de696c6e8d7 692 Pfam PF00679 Elongation factor G C-terminus 601 685 2.0E-29 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like TSH58p_15150 bd5bbf6d90ed4817fcfb4de696c6e8d7 692 Pfam PF03764 Elongation factor G, domain IV 479 597 1.7E-45 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TSH58p_15150 bd5bbf6d90ed4817fcfb4de696c6e8d7 692 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 690 0.0 T 14-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TSH58p_15150 bd5bbf6d90ed4817fcfb4de696c6e8d7 692 Pfam PF03144 Elongation factor Tu domain 2 324 391 8.0E-15 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TSH58p_15150 bd5bbf6d90ed4817fcfb4de696c6e8d7 692 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site TSH58p_15150 bd5bbf6d90ed4817fcfb4de696c6e8d7 692 SMART SM00889 480 598 2.2E-67 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TSH58p_15150 bd5bbf6d90ed4817fcfb4de696c6e8d7 692 SUPERFAMILY SSF52540 6 281 1.57E-106 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_15150 bd5bbf6d90ed4817fcfb4de696c6e8d7 692 Hamap MF_00054_B Elongation factor G [fusA]. 6 691 110.561 T 14-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TSH58p_15150 bd5bbf6d90ed4817fcfb4de696c6e8d7 692 SUPERFAMILY SSF50447 250 402 2.78E-36 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSH58p_15150 bd5bbf6d90ed4817fcfb4de696c6e8d7 692 Pfam PF14492 Elongation Factor G, domain II 404 477 7.1E-34 T 14-10-2018 TSH58p_15150 bd5bbf6d90ed4817fcfb4de696c6e8d7 692 Gene3D G3DSA:3.30.70.240 604 674 7.1E-90 T 14-10-2018 TSH58p_15150 bd5bbf6d90ed4817fcfb4de696c6e8d7 692 Gene3D G3DSA:3.30.230.10 484 687 7.1E-90 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSH58p_15150 bd5bbf6d90ed4817fcfb4de696c6e8d7 692 Gene3D G3DSA:3.40.50.300 1 287 1.2E-110 T 14-10-2018 TSH58p_15150 bd5bbf6d90ed4817fcfb4de696c6e8d7 692 Gene3D G3DSA:2.40.30.10 291 405 7.2E-42 T 14-10-2018 TSH58p_15150 bd5bbf6d90ed4817fcfb4de696c6e8d7 692 SUPERFAMILY SSF54211 479 599 1.52E-43 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSH58p_12030 369ac8c46448aef662c99bc04514c42b 411 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 15 23 - T 14-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TSH58p_12030 369ac8c46448aef662c99bc04514c42b 411 TIGRFAM TIGR00032 argG: argininosuccinate synthase 11 401 9.9E-142 T 14-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TSH58p_12030 369ac8c46448aef662c99bc04514c42b 411 Pfam PF00764 Arginosuccinate synthase 13 401 7.8E-154 T 14-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TSH58p_12030 369ac8c46448aef662c99bc04514c42b 411 Gene3D G3DSA:3.40.50.620 10 181 7.5E-68 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_12030 369ac8c46448aef662c99bc04514c42b 411 Hamap MF_00005 Argininosuccinate synthase [argG]. 9 408 52.658 T 14-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TSH58p_12030 369ac8c46448aef662c99bc04514c42b 411 SUPERFAMILY SSF52402 10 175 2.43E-47 T 14-10-2018 TSH58p_12030 369ac8c46448aef662c99bc04514c42b 411 SUPERFAMILY SSF69864 182 408 1.31E-93 T 14-10-2018 TSH58p_12030 369ac8c46448aef662c99bc04514c42b 411 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 125 136 - T 14-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TSH58p_12030 369ac8c46448aef662c99bc04514c42b 411 Gene3D G3DSA:3.90.1260.10 185 410 3.6E-98 T 14-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TSH58p_31785 c0f6b7e3c2b852a76d90dbf85b6e9e6c 233 SUPERFAMILY SSF46785 23 89 1.12E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_31785 c0f6b7e3c2b852a76d90dbf85b6e9e6c 233 Gene3D G3DSA:1.20.120.530 89 229 2.5E-29 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_31785 c0f6b7e3c2b852a76d90dbf85b6e9e6c 233 Gene3D G3DSA:1.10.10.10 17 86 8.8E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_31785 c0f6b7e3c2b852a76d90dbf85b6e9e6c 233 SUPERFAMILY SSF48008 91 225 6.28E-26 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_31785 c0f6b7e3c2b852a76d90dbf85b6e9e6c 233 SMART SM00895 95 222 2.9E-19 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_31785 c0f6b7e3c2b852a76d90dbf85b6e9e6c 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 85 3.3E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_31785 c0f6b7e3c2b852a76d90dbf85b6e9e6c 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 59 1.8E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_31785 c0f6b7e3c2b852a76d90dbf85b6e9e6c 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 59 75 1.8E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_31785 c0f6b7e3c2b852a76d90dbf85b6e9e6c 233 Pfam PF07729 FCD domain 95 221 1.6E-25 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_31785 c0f6b7e3c2b852a76d90dbf85b6e9e6c 233 SMART SM00345 27 85 4.3E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_01435 ca3ca8cf4d5270714d8c37a556946f24 221 Gene3D G3DSA:1.10.357.10 14 210 1.8E-26 T 14-10-2018 TSH58p_01435 ca3ca8cf4d5270714d8c37a556946f24 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 73 1.5E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_01435 ca3ca8cf4d5270714d8c37a556946f24 221 SUPERFAMILY SSF46689 15 96 3.8E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_01435 ca3ca8cf4d5270714d8c37a556946f24 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 4.7E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_01435 ca3ca8cf4d5270714d8c37a556946f24 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 4.7E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_02370 02561b3583008c8605fe63cecca87baa 457 Pfam PF13533 Biotin-lipoyl like 119 166 4.1E-14 T 14-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain TSH58p_02370 02561b3583008c8605fe63cecca87baa 457 Gene3D G3DSA:2.40.50.100 118 262 4.2E-68 T 14-10-2018 TSH58p_02370 02561b3583008c8605fe63cecca87baa 457 SUPERFAMILY SSF111369 111 345 2.22E-57 T 14-10-2018 TSH58p_02370 02561b3583008c8605fe63cecca87baa 457 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 94 423 2.1E-73 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 TSH58p_02370 02561b3583008c8605fe63cecca87baa 457 Gene3D G3DSA:1.10.287.470 153 226 4.2E-68 T 14-10-2018 TSH58p_02370 02561b3583008c8605fe63cecca87baa 457 Gene3D G3DSA:2.40.420.20 331 424 3.2E-20 T 14-10-2018 TSH58p_02370 02561b3583008c8605fe63cecca87baa 457 Gene3D G3DSA:2.40.30.170 112 330 4.2E-68 T 14-10-2018 TSH58p_02370 02561b3583008c8605fe63cecca87baa 457 Pfam PF13437 HlyD family secretion protein 230 331 3.7E-5 T 14-10-2018 TSH58p_25190 d1dbac0f820560bd00dc18e0f0fd85d3 149 Gene3D G3DSA:1.10.10.10 8 90 1.3E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_25190 d1dbac0f820560bd00dc18e0f0fd85d3 149 Pfam PF01475 Ferric uptake regulator family 18 136 1.1E-35 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 TSH58p_25190 d1dbac0f820560bd00dc18e0f0fd85d3 149 Gene3D G3DSA:3.30.1490.190 93 142 1.2E-13 T 14-10-2018 TSH58p_25190 d1dbac0f820560bd00dc18e0f0fd85d3 149 SUPERFAMILY SSF46785 12 139 3.98E-36 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_05115 cde2b82a8d9d99068b5944f3a0499fda 302 SUPERFAMILY SSF51735 1 160 2.92E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_05115 cde2b82a8d9d99068b5944f3a0499fda 302 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 160 2.2E-52 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 TSH58p_05115 cde2b82a8d9d99068b5944f3a0499fda 302 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 163 283 9.3E-39 T 14-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 TSH58p_05115 cde2b82a8d9d99068b5944f3a0499fda 302 PIRSF PIRSF000103 1 292 2.3E-73 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 TSH58p_05115 cde2b82a8d9d99068b5944f3a0499fda 302 Gene3D G3DSA:1.10.1040.10 159 292 1.8E-38 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSH58p_05115 cde2b82a8d9d99068b5944f3a0499fda 302 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 5 18 - T 14-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 TSH58p_05115 cde2b82a8d9d99068b5944f3a0499fda 302 TIGRFAM TIGR01505 tartro_sem_red: 2-hydroxy-3-oxopropionate reductase 3 291 1.1E-126 T 14-10-2018 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 TSH58p_05115 cde2b82a8d9d99068b5944f3a0499fda 302 Gene3D G3DSA:3.40.50.720 1 158 2.3E-57 T 14-10-2018 TSH58p_05115 cde2b82a8d9d99068b5944f3a0499fda 302 SUPERFAMILY SSF48179 162 291 5.33E-36 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_24335 87cf13713eefaf3253238cd1d6ecbb9c 146 SUPERFAMILY SSF46785 16 138 3.51E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_24335 87cf13713eefaf3253238cd1d6ecbb9c 146 Gene3D G3DSA:1.10.10.10 7 143 7.9E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_24335 87cf13713eefaf3253238cd1d6ecbb9c 146 SMART SM00347 23 122 5.2E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_24335 87cf13713eefaf3253238cd1d6ecbb9c 146 Pfam PF12802 MarR family 29 89 3.3E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_16780 4e00ce449b9a3cbb4be46508f8151b2f 1163 Gene3D G3DSA:3.20.20.20 332 625 7.5E-99 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSH58p_16780 4e00ce449b9a3cbb4be46508f8151b2f 1163 PIRSF PIRSF000381 1 1163 0.0 T 14-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSH58p_16780 4e00ce449b9a3cbb4be46508f8151b2f 1163 Pfam PF02574 Homocysteine S-methyltransferase 13 301 7.4E-60 T 14-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 TSH58p_16780 4e00ce449b9a3cbb4be46508f8151b2f 1163 Gene3D G3DSA:3.20.20.330 2 313 2.6E-86 T 14-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 TSH58p_16780 4e00ce449b9a3cbb4be46508f8151b2f 1163 Pfam PF00809 Pterin binding enzyme 346 579 1.1E-39 T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSH58p_16780 4e00ce449b9a3cbb4be46508f8151b2f 1163 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 917 1163 1.2E-42 T 14-10-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSH58p_16780 4e00ce449b9a3cbb4be46508f8151b2f 1163 SUPERFAMILY SSF82282 2 385 1.07E-101 T 14-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 TSH58p_16780 4e00ce449b9a3cbb4be46508f8151b2f 1163 SUPERFAMILY SSF52242 718 847 1.7E-37 T 14-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 TSH58p_16780 4e00ce449b9a3cbb4be46508f8151b2f 1163 Gene3D G3DSA:1.10.1240.10 626 713 1.3E-31 T 14-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSH58p_16780 4e00ce449b9a3cbb4be46508f8151b2f 1163 SMART SM01018 634 716 1.1E-42 T 14-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSH58p_16780 4e00ce449b9a3cbb4be46508f8151b2f 1163 SUPERFAMILY SSF56507 888 1163 1.31E-90 T 14-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSH58p_16780 4e00ce449b9a3cbb4be46508f8151b2f 1163 Gene3D G3DSA:3.10.196.10 899 1163 1.2E-59 T 14-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSH58p_16780 4e00ce449b9a3cbb4be46508f8151b2f 1163 SUPERFAMILY SSF51717 342 611 1.18E-73 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSH58p_16780 4e00ce449b9a3cbb4be46508f8151b2f 1163 Gene3D G3DSA:3.40.50.280 718 868 1.9E-41 T 14-10-2018 TSH58p_16780 4e00ce449b9a3cbb4be46508f8151b2f 1163 Pfam PF02607 B12 binding domain 636 709 2.7E-25 T 14-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSH58p_16780 4e00ce449b9a3cbb4be46508f8151b2f 1163 Gene3D G3DSA:1.10.288.10 915 973 1.2E-59 T 14-10-2018 TSH58p_16780 4e00ce449b9a3cbb4be46508f8151b2f 1163 TIGRFAM TIGR02082 metH: methionine synthase 9 1163 0.0 T 14-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSH58p_16780 4e00ce449b9a3cbb4be46508f8151b2f 1163 Pfam PF02310 B12 binding domain 723 815 3.9E-19 T 14-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 TSH58p_16780 4e00ce449b9a3cbb4be46508f8151b2f 1163 SUPERFAMILY SSF47644 631 714 5.62E-25 T 14-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSH58p_03260 5bd4df390743587f7be227109439dc77 553 SUPERFAMILY SSF58104 231 546 1.31E-59 T 14-10-2018 TSH58p_03260 5bd4df390743587f7be227109439dc77 553 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 362 524 1.0E-29 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_03260 5bd4df390743587f7be227109439dc77 553 SUPERFAMILY SSF103190 77 171 1.94E-12 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily TSH58p_03260 5bd4df390743587f7be227109439dc77 553 Gene3D G3DSA:1.10.287.950 253 548 8.6E-52 T 14-10-2018 TSH58p_03260 5bd4df390743587f7be227109439dc77 553 Pfam PF17202 Single cache domain 3 74 177 4.4E-34 T 14-10-2018 IPR033463 Single cache domain 3 TSH58p_03260 5bd4df390743587f7be227109439dc77 553 Pfam PF00672 HAMP domain 203 253 7.2E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_03260 5bd4df390743587f7be227109439dc77 553 Gene3D G3DSA:1.10.8.500 204 252 2.4E-16 T 14-10-2018 TSH58p_03260 5bd4df390743587f7be227109439dc77 553 SMART SM00283 293 547 3.6E-40 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_03260 5bd4df390743587f7be227109439dc77 553 SMART SM00304 488 544 95.0 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_03260 5bd4df390743587f7be227109439dc77 553 SMART SM00304 203 256 7.3E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_13405 14c7b21668122716308d3634bd54d78c 191 Pfam PF04955 HupE / UreJ protein 21 184 8.0E-19 T 14-10-2018 IPR007038 Hydrogenase/Urease accessory protein HupE/UreJ protein TSH58p_00445 49cac1bb78384a34d1e8fc82dcb1f9ab 497 Pfam PF00171 Aldehyde dehydrogenase family 31 492 1.1E-159 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TSH58p_00445 49cac1bb78384a34d1e8fc82dcb1f9ab 497 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 TSH58p_00445 49cac1bb78384a34d1e8fc82dcb1f9ab 497 Gene3D G3DSA:3.40.309.10 267 461 2.0E-165 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TSH58p_00445 49cac1bb78384a34d1e8fc82dcb1f9ab 497 SUPERFAMILY SSF53720 18 495 6.15E-158 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSH58p_00445 49cac1bb78384a34d1e8fc82dcb1f9ab 497 Gene3D G3DSA:3.40.605.10 25 489 2.0E-165 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TSH58p_00445 49cac1bb78384a34d1e8fc82dcb1f9ab 497 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 291 302 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 TSH58p_00525 62dda054cfc42e207f78aa01e8490fc6 441 SUPERFAMILY SSF51445 3 436 5.88E-152 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_00525 62dda054cfc42e207f78aa01e8490fc6 441 TIGRFAM TIGR03356 BGL: beta-galactosidase 5 430 5.8E-168 T 14-10-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092|MetaCyc: PWY-7913 TSH58p_00525 62dda054cfc42e207f78aa01e8490fc6 441 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 8 22 - T 14-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site TSH58p_00525 62dda054cfc42e207f78aa01e8490fc6 441 Gene3D G3DSA:3.20.20.80 1 439 2.2E-157 T 14-10-2018 TSH58p_00525 62dda054cfc42e207f78aa01e8490fc6 441 Pfam PF00232 Glycosyl hydrolase family 1 3 436 1.2E-144 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSH58p_00525 62dda054cfc42e207f78aa01e8490fc6 441 PRINTS PR00131 Glycosyl hydrolase family 1 signature 384 401 1.4E-18 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSH58p_00525 62dda054cfc42e207f78aa01e8490fc6 441 PRINTS PR00131 Glycosyl hydrolase family 1 signature 408 420 1.4E-18 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSH58p_00525 62dda054cfc42e207f78aa01e8490fc6 441 PRINTS PR00131 Glycosyl hydrolase family 1 signature 280 294 1.4E-18 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSH58p_00525 62dda054cfc42e207f78aa01e8490fc6 441 PRINTS PR00131 Glycosyl hydrolase family 1 signature 363 374 1.4E-18 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSH58p_00525 62dda054cfc42e207f78aa01e8490fc6 441 PRINTS PR00131 Glycosyl hydrolase family 1 signature 342 350 1.4E-18 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSH58p_23915 cde96d84804c0e24a3d70ee1a027e224 189 Gene3D G3DSA:1.20.5.510 14 53 8.5E-19 T 14-10-2018 TSH58p_23915 cde96d84804c0e24a3d70ee1a027e224 189 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 22 189 9.8E-71 T 14-10-2018 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 TSH58p_23915 cde96d84804c0e24a3d70ee1a027e224 189 Pfam PF00355 Rieske [2Fe-2S] domain 115 174 9.1E-11 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TSH58p_23915 cde96d84804c0e24a3d70ee1a027e224 189 SUPERFAMILY SSF50022 44 185 1.31E-40 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TSH58p_23915 cde96d84804c0e24a3d70ee1a027e224 189 Gene3D G3DSA:2.102.10.10 54 186 5.1E-53 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TSH58p_23915 cde96d84804c0e24a3d70ee1a027e224 189 Pfam PF10399 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal 18 53 2.6E-20 T 14-10-2018 IPR019470 Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signal GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 TSH58p_23915 cde96d84804c0e24a3d70ee1a027e224 189 PRINTS PR00162 Rieske 2Fe-2S subunit signature 122 133 9.7E-17 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 TSH58p_23915 cde96d84804c0e24a3d70ee1a027e224 189 PRINTS PR00162 Rieske 2Fe-2S subunit signature 149 161 9.7E-17 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 TSH58p_23915 cde96d84804c0e24a3d70ee1a027e224 189 PRINTS PR00162 Rieske 2Fe-2S subunit signature 161 173 9.7E-17 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 TSH58p_23915 cde96d84804c0e24a3d70ee1a027e224 189 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 22 46 1.6E-5 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal TSH58p_07785 de25f4857e1c7e7767d65482493cf86c 729 Pfam PF13538 UvrD-like helicase C-terminal domain 653 699 2.2E-17 T 14-10-2018 IPR027785 UvrD-like helicase C-terminal domain TSH58p_07785 de25f4857e1c7e7767d65482493cf86c 729 Gene3D G3DSA:1.10.10.2220 194 290 1.3E-15 T 14-10-2018 TSH58p_07785 de25f4857e1c7e7767d65482493cf86c 729 SUPERFAMILY SSF52540 192 491 6.49E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_07785 de25f4857e1c7e7767d65482493cf86c 729 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 16 724 1.1E-212 T 14-10-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 TSH58p_07785 de25f4857e1c7e7767d65482493cf86c 729 Gene3D G3DSA:3.40.50.300 491 716 6.5E-153 T 14-10-2018 TSH58p_07785 de25f4857e1c7e7767d65482493cf86c 729 Gene3D G3DSA:2.30.30.940 582 653 6.5E-153 T 14-10-2018 TSH58p_07785 de25f4857e1c7e7767d65482493cf86c 729 SUPERFAMILY SSF52540 443 716 1.24E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_07785 de25f4857e1c7e7767d65482493cf86c 729 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 13 729 28.193 T 14-10-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 TSH58p_07785 de25f4857e1c7e7767d65482493cf86c 729 SMART SM00382 346 526 1.7E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_07785 de25f4857e1c7e7767d65482493cf86c 729 Pfam PF14490 Helix-hairpin-helix containing domain 153 241 1.3E-29 T 14-10-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain TSH58p_07785 de25f4857e1c7e7767d65482493cf86c 729 Gene3D G3DSA:3.40.50.300 319 722 6.5E-153 T 14-10-2018 TSH58p_07785 de25f4857e1c7e7767d65482493cf86c 729 SUPERFAMILY SSF47781 97 169 5.56E-12 T 14-10-2018 IPR010994 RuvA domain 2-like TSH58p_07785 de25f4857e1c7e7767d65482493cf86c 729 Gene3D G3DSA:1.10.150.20 86 154 3.5E-11 T 14-10-2018 TSH58p_07785 de25f4857e1c7e7767d65482493cf86c 729 Pfam PF14520 Helix-hairpin-helix domain 102 151 2.1E-11 T 14-10-2018 TSH58p_07785 de25f4857e1c7e7767d65482493cf86c 729 SMART SM00278 130 149 0.079 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TSH58p_07785 de25f4857e1c7e7767d65482493cf86c 729 SMART SM00278 194 213 71.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TSH58p_07785 de25f4857e1c7e7767d65482493cf86c 729 Pfam PF13604 AAA domain 332 514 7.6E-47 T 14-10-2018 TSH58p_17255 5b0e9e88b0710cea496a54485931d96f 372 SUPERFAMILY SSF53927 10 151 6.67E-45 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TSH58p_17255 5b0e9e88b0710cea496a54485931d96f 372 Gene3D G3DSA:3.40.430.10 149 369 1.1E-66 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TSH58p_17255 5b0e9e88b0710cea496a54485931d96f 372 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 14 365 7.0E-98 T 14-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 TSH58p_17255 5b0e9e88b0710cea496a54485931d96f 372 Gene3D G3DSA:3.40.140.10 3 148 2.3E-43 T 14-10-2018 TSH58p_17255 5b0e9e88b0710cea496a54485931d96f 372 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 153 365 2.4E-50 T 14-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 TSH58p_17255 5b0e9e88b0710cea496a54485931d96f 372 Pfam PF01872 RibD C-terminal domain 157 341 1.2E-43 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 TSH58p_17255 5b0e9e88b0710cea496a54485931d96f 372 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 11 106 1.6E-14 T 14-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain TSH58p_17255 5b0e9e88b0710cea496a54485931d96f 372 PIRSF PIRSF006769 6 372 1.4E-125 T 14-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 TSH58p_17255 5b0e9e88b0710cea496a54485931d96f 372 SUPERFAMILY SSF53597 152 367 3.93E-58 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TSH58p_04645 78d5722ec43f54c576b57e9986e29e7a 296 PRINTS PR00046 Major sigma-70 factor signature 74 87 2.7E-21 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_04645 78d5722ec43f54c576b57e9986e29e7a 296 PRINTS PR00046 Major sigma-70 factor signature 231 243 2.7E-21 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_04645 78d5722ec43f54c576b57e9986e29e7a 296 PRINTS PR00046 Major sigma-70 factor signature 98 106 2.7E-21 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_04645 78d5722ec43f54c576b57e9986e29e7a 296 PRINTS PR00046 Major sigma-70 factor signature 250 265 2.7E-21 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_04645 78d5722ec43f54c576b57e9986e29e7a 296 PRINTS PR00046 Major sigma-70 factor signature 265 276 2.7E-21 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_04645 78d5722ec43f54c576b57e9986e29e7a 296 Gene3D G3DSA:1.10.10.10 210 284 4.4E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_04645 78d5722ec43f54c576b57e9986e29e7a 296 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 12 281 4.4E-100 T 14-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_04645 78d5722ec43f54c576b57e9986e29e7a 296 Pfam PF04545 Sigma-70, region 4 227 278 8.3E-13 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 TSH58p_04645 78d5722ec43f54c576b57e9986e29e7a 296 Gene3D G3DSA:1.10.10.10 132 204 8.8E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_04645 78d5722ec43f54c576b57e9986e29e7a 296 Pfam PF04542 Sigma-70 region 2 50 114 2.0E-17 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_04645 78d5722ec43f54c576b57e9986e29e7a 296 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 45 279 1.9E-29 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TSH58p_04645 78d5722ec43f54c576b57e9986e29e7a 296 SUPERFAMILY SSF88946 10 118 8.77E-36 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_04645 78d5722ec43f54c576b57e9986e29e7a 296 SUPERFAMILY SSF88659 188 280 8.78E-17 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSH58p_04645 78d5722ec43f54c576b57e9986e29e7a 296 Gene3D G3DSA:1.20.120.1810 2 117 3.1E-32 T 14-10-2018 TSH58p_13680 4a0d8677a745967409d990ab0eb82cd2 165 PRINTS PR00502 NUDIX hydrolase family signature 54 69 1.9E-5 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TSH58p_13680 4a0d8677a745967409d990ab0eb82cd2 165 PRINTS PR00502 NUDIX hydrolase family signature 40 54 1.9E-5 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TSH58p_13680 4a0d8677a745967409d990ab0eb82cd2 165 Pfam PF00293 NUDIX domain 13 149 1.3E-25 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TSH58p_13680 4a0d8677a745967409d990ab0eb82cd2 165 SUPERFAMILY SSF55811 5 157 1.76E-32 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TSH58p_13680 4a0d8677a745967409d990ab0eb82cd2 165 Gene3D G3DSA:3.90.79.10 3 159 2.7E-45 T 14-10-2018 TSH58p_13680 4a0d8677a745967409d990ab0eb82cd2 165 ProSitePatterns PS00893 Nudix box signature. 45 66 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TSH58p_13680 4a0d8677a745967409d990ab0eb82cd2 165 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 7 160 34.364 T 14-10-2018 IPR022927 RNA pyrophosphohydrolase RppH TSH58p_31175 21b49f30e0be71492896771a380d1883 153 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 51 1.1E-16 T 14-10-2018 TSH58p_31175 21b49f30e0be71492896771a380d1883 153 SUPERFAMILY SSF54909 64 153 1.74E-24 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel TSH58p_31175 21b49f30e0be71492896771a380d1883 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 8.9E-17 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSH58p_31175 21b49f30e0be71492896771a380d1883 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 8.9E-17 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSH58p_31175 21b49f30e0be71492896771a380d1883 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 8.9E-17 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSH58p_31175 21b49f30e0be71492896771a380d1883 153 Pfam PF01037 Lrp/AsnC ligand binding domain 70 144 2.1E-23 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TSH58p_31175 21b49f30e0be71492896771a380d1883 153 Gene3D G3DSA:1.10.10.10 1 57 1.3E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_31175 21b49f30e0be71492896771a380d1883 153 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 14-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site TSH58p_31175 21b49f30e0be71492896771a380d1883 153 Gene3D G3DSA:3.30.70.920 58 141 1.3E-25 T 14-10-2018 TSH58p_31175 21b49f30e0be71492896771a380d1883 153 SUPERFAMILY SSF46785 3 93 7.77E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_31175 21b49f30e0be71492896771a380d1883 153 SMART SM00344 4 113 1.6E-44 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TSH58p_11945 01dea6be61e83ce1bbae2a95cc75e0fe 600 SUPERFAMILY SSF52540 1 220 6.9E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_11945 01dea6be61e83ce1bbae2a95cc75e0fe 600 Hamap MF_00071 Elongation factor 4 [lepA]. 1 600 304.045 T 14-10-2018 IPR006297 Elongation factor 4 GO:0005525 TSH58p_11945 01dea6be61e83ce1bbae2a95cc75e0fe 600 SUPERFAMILY SSF54980 402 496 3.41E-24 T 14-10-2018 IPR035647 EF-G domain III/V-like TSH58p_11945 01dea6be61e83ce1bbae2a95cc75e0fe 600 Pfam PF06421 GTP-binding protein LepA C-terminus 490 596 8.6E-51 T 14-10-2018 IPR013842 GTP-binding protein LepA, C-terminal TSH58p_11945 01dea6be61e83ce1bbae2a95cc75e0fe 600 SUPERFAMILY SSF54980 296 373 1.94E-18 T 14-10-2018 IPR035647 EF-G domain III/V-like TSH58p_11945 01dea6be61e83ce1bbae2a95cc75e0fe 600 Pfam PF00009 Elongation factor Tu GTP binding domain 6 184 7.3E-53 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_11945 01dea6be61e83ce1bbae2a95cc75e0fe 600 Pfam PF00679 Elongation factor G C-terminus 402 487 1.0E-20 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like TSH58p_11945 01dea6be61e83ce1bbae2a95cc75e0fe 600 TIGRFAM TIGR01393 lepA: elongation factor 4 6 597 2.3E-292 T 14-10-2018 IPR006297 Elongation factor 4 GO:0005525 TSH58p_11945 01dea6be61e83ce1bbae2a95cc75e0fe 600 Gene3D G3DSA:3.30.70.870 289 370 2.1E-34 T 14-10-2018 TSH58p_11945 01dea6be61e83ce1bbae2a95cc75e0fe 600 Gene3D G3DSA:3.40.50.300 3 188 6.9E-73 T 14-10-2018 TSH58p_11945 01dea6be61e83ce1bbae2a95cc75e0fe 600 PRINTS PR00315 GTP-binding elongation factor signature 52 60 1.0E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_11945 01dea6be61e83ce1bbae2a95cc75e0fe 600 PRINTS PR00315 GTP-binding elongation factor signature 9 22 1.0E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_11945 01dea6be61e83ce1bbae2a95cc75e0fe 600 PRINTS PR00315 GTP-binding elongation factor signature 93 104 1.0E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_11945 01dea6be61e83ce1bbae2a95cc75e0fe 600 PRINTS PR00315 GTP-binding elongation factor signature 129 138 1.0E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_11945 01dea6be61e83ce1bbae2a95cc75e0fe 600 PRINTS PR00315 GTP-binding elongation factor signature 77 87 1.0E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_11945 01dea6be61e83ce1bbae2a95cc75e0fe 600 Pfam PF03144 Elongation factor Tu domain 2 208 278 1.6E-7 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TSH58p_11945 01dea6be61e83ce1bbae2a95cc75e0fe 600 Gene3D G3DSA:3.30.70.2570 482 556 6.5E-36 T 14-10-2018 IPR038363 LepA, C-terminal domain superfamily TSH58p_11945 01dea6be61e83ce1bbae2a95cc75e0fe 600 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 179 3.3E-20 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSH58p_11945 01dea6be61e83ce1bbae2a95cc75e0fe 600 Gene3D G3DSA:2.40.30.10 189 288 4.4E-30 T 14-10-2018 TSH58p_11945 01dea6be61e83ce1bbae2a95cc75e0fe 600 SUPERFAMILY SSF50447 191 283 4.35E-16 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSH58p_11945 01dea6be61e83ce1bbae2a95cc75e0fe 600 SMART SM00838 401 492 0.0066 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like TSH58p_11945 01dea6be61e83ce1bbae2a95cc75e0fe 600 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 45 60 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site TSH58p_11945 01dea6be61e83ce1bbae2a95cc75e0fe 600 Gene3D G3DSA:3.30.70.3380 371 481 7.3E-41 T 14-10-2018 TSH58p_13595 8ac1dc382a45852231e9962d1abe547a 481 Pfam PF00294 pfkB family carbohydrate kinase 14 307 1.7E-35 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB TSH58p_13595 8ac1dc382a45852231e9962d1abe547a 481 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 54 77 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TSH58p_13595 8ac1dc382a45852231e9962d1abe547a 481 TIGRFAM TIGR02198 rfaE_dom_I: bifunctional protein RfaE, domain I 9 318 1.3E-111 T 14-10-2018 IPR011913 RfaE bifunctional protein, domain I GO:0005975|GO:0016773|GO:0016779 KEGG: 00540+2.7.7.70+2.7.1.167 TSH58p_13595 8ac1dc382a45852231e9962d1abe547a 481 Hamap MF_01603 Bifunctional protein HldE [hldE]. 7 481 41.82 T 14-10-2018 IPR023030 Bifunctional protein HldE GO:0016773|GO:0016779 KEGG: 00540+2.7.7.70+2.7.1.167 TSH58p_13595 8ac1dc382a45852231e9962d1abe547a 481 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 350 415 1.5E-14 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TSH58p_13595 8ac1dc382a45852231e9962d1abe547a 481 SUPERFAMILY SSF52374 348 479 4.79E-23 T 14-10-2018 TSH58p_13595 8ac1dc382a45852231e9962d1abe547a 481 Pfam PF01467 Cytidylyltransferase-like 353 445 1.3E-13 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TSH58p_13595 8ac1dc382a45852231e9962d1abe547a 481 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 340 480 1.2E-63 T 14-10-2018 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00540+2.7.7.70+2.7.1.167 TSH58p_13595 8ac1dc382a45852231e9962d1abe547a 481 Gene3D G3DSA:3.40.50.620 328 481 1.5E-38 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_13595 8ac1dc382a45852231e9962d1abe547a 481 Gene3D G3DSA:3.40.1190.20 5 316 7.0E-103 T 14-10-2018 IPR029056 Ribokinase-like TSH58p_13595 8ac1dc382a45852231e9962d1abe547a 481 SUPERFAMILY SSF53613 16 321 2.81E-56 T 14-10-2018 IPR029056 Ribokinase-like TSH58p_30595 d0de621edf3d5ea0e234f9f49ab4d2fe 290 Gene3D G3DSA:1.10.3720.10 91 282 1.5E-17 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_30595 d0de621edf3d5ea0e234f9f49ab4d2fe 290 SUPERFAMILY SSF161098 90 274 4.97E-26 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_30595 d0de621edf3d5ea0e234f9f49ab4d2fe 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 282 1.3E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_20790 75052c1ac7019163ef73c0752919e211 355 SUPERFAMILY SSF89733 24 352 3.53E-101 T 14-10-2018 IPR036111 Malate/L-sulfolactate/L-lactate dehydrogenase-like superfamily GO:0016491|GO:0055114 TSH58p_20790 75052c1ac7019163ef73c0752919e211 355 Gene3D G3DSA:1.10.1530.10 32 348 7.1E-112 T 14-10-2018 TSH58p_20790 75052c1ac7019163ef73c0752919e211 355 Gene3D G3DSA:3.30.1370.60 82 321 7.1E-112 T 14-10-2018 TSH58p_20790 75052c1ac7019163ef73c0752919e211 355 Gene3D G3DSA:3.30.60.50 198 246 7.1E-112 T 14-10-2018 TSH58p_20790 75052c1ac7019163ef73c0752919e211 355 Pfam PF02615 Malate/L-lactate dehydrogenase 25 348 4.5E-104 T 14-10-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0016491|GO:0055114 TSH58p_28815 8676547feadf6a509f501a7f3462ed73 203 SMART SM00530 29 84 5.1E-8 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_28815 8676547feadf6a509f501a7f3462ed73 203 SUPERFAMILY SSF47413 25 86 3.1E-12 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_28815 8676547feadf6a509f501a7f3462ed73 203 SUPERFAMILY SSF51182 77 201 1.35E-22 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_28815 8676547feadf6a509f501a7f3462ed73 203 Gene3D G3DSA:1.10.260.40 21 90 8.8E-13 T 14-10-2018 TSH58p_28815 8676547feadf6a509f501a7f3462ed73 203 Gene3D G3DSA:2.60.120.10 112 202 4.4E-26 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_28815 8676547feadf6a509f501a7f3462ed73 203 Pfam PF07883 Cupin domain 130 198 4.1E-11 T 14-10-2018 IPR013096 Cupin 2, conserved barrel TSH58p_28815 8676547feadf6a509f501a7f3462ed73 203 Pfam PF01381 Helix-turn-helix 30 82 1.0E-8 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_19310 760e55a1eb5353ee989283d7571fe791 343 Pfam PF01497 Periplasmic binding protein 87 274 9.6E-20 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain TSH58p_19310 760e55a1eb5353ee989283d7571fe791 343 Gene3D G3DSA:3.40.50.1980 182 284 1.1E-54 T 14-10-2018 TSH58p_19310 760e55a1eb5353ee989283d7571fe791 343 Gene3D G3DSA:3.40.50.1980 18 152 1.4E-34 T 14-10-2018 TSH58p_19310 760e55a1eb5353ee989283d7571fe791 343 SUPERFAMILY SSF53807 24 337 1.84E-51 T 14-10-2018 TSH58p_19310 760e55a1eb5353ee989283d7571fe791 343 Gene3D G3DSA:1.20.58.2180 157 330 1.1E-54 T 14-10-2018 TSH58p_14465 951740af075c209a99912c23f9870dcf 254 Gene3D G3DSA:3.40.50.150 8 250 1.0E-62 T 14-10-2018 TSH58p_14465 951740af075c209a99912c23f9870dcf 254 Pfam PF05175 Methyltransferase small domain 33 135 3.0E-11 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 TSH58p_14465 951740af075c209a99912c23f9870dcf 254 SUPERFAMILY SSF53335 17 217 5.97E-34 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_06260 e7555b6c0cb644f06f99f55fa7d2b577 179 Gene3D G3DSA:3.40.980.10 2 179 1.1E-61 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSH58p_06260 e7555b6c0cb644f06f99f55fa7d2b577 179 Pfam PF00994 Probable molybdopterin binding domain 10 154 2.8E-32 T 14-10-2018 IPR001453 MoaB/Mog domain TSH58p_06260 e7555b6c0cb644f06f99f55fa7d2b577 179 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 72 85 - T 14-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 TSH58p_06260 e7555b6c0cb644f06f99f55fa7d2b577 179 SMART SM00852 10 156 2.3E-31 T 14-10-2018 IPR001453 MoaB/Mog domain TSH58p_06260 e7555b6c0cb644f06f99f55fa7d2b577 179 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 8 149 3.2E-40 T 14-10-2018 IPR001453 MoaB/Mog domain TSH58p_06260 e7555b6c0cb644f06f99f55fa7d2b577 179 SUPERFAMILY SSF53218 6 178 1.83E-48 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSH58p_29025 da9037af457b2595b81025bbb3894ace 1247 Pfam PF03797 Autotransporter beta-domain 975 1227 7.1E-66 T 14-10-2018 IPR005546 Autotransporter beta-domain TSH58p_29025 da9037af457b2595b81025bbb3894ace 1247 SUPERFAMILY SSF103515 922 1247 1.96E-64 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily TSH58p_29025 da9037af457b2595b81025bbb3894ace 1247 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 738 1247 4.6E-41 T 14-10-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 TSH58p_29025 da9037af457b2595b81025bbb3894ace 1247 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 514 651 2.7E-5 T 14-10-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 TSH58p_29025 da9037af457b2595b81025bbb3894ace 1247 SMART SM00869 972 1237 1.9E-56 T 14-10-2018 IPR005546 Autotransporter beta-domain TSH58p_29025 da9037af457b2595b81025bbb3894ace 1247 SUPERFAMILY SSF51126 190 610 2.29E-5 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor TSH58p_29025 da9037af457b2595b81025bbb3894ace 1247 Gene3D G3DSA:2.40.128.130 954 1247 2.2E-74 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily TSH58p_20730 16f7029b1c0a133f8cbe697094f687ca 482 Pfam PF00263 Bacterial type II and III secretion system protein 256 417 6.5E-45 T 14-10-2018 IPR004846 Type II/III secretion system GO:0009306 TSH58p_20730 16f7029b1c0a133f8cbe697094f687ca 482 Pfam PF04972 BON domain 117 175 5.8E-9 T 14-10-2018 IPR007055 BON domain TSH58p_20730 16f7029b1c0a133f8cbe697094f687ca 482 Pfam PF13629 Pilus formation protein N terminal region 41 111 2.4E-15 T 14-10-2018 IPR032789 Pilus formation protein, N-terminal TSH58p_20730 16f7029b1c0a133f8cbe697094f687ca 482 PRINTS PR00811 Bacterial general secretion pathway protein D signature 381 399 6.1E-12 T 14-10-2018 IPR001775 GspD/PilQ family TSH58p_20730 16f7029b1c0a133f8cbe697094f687ca 482 PRINTS PR00811 Bacterial general secretion pathway protein D signature 404 418 6.1E-12 T 14-10-2018 IPR001775 GspD/PilQ family TSH58p_20730 16f7029b1c0a133f8cbe697094f687ca 482 PRINTS PR00811 Bacterial general secretion pathway protein D signature 179 189 6.1E-12 T 14-10-2018 IPR001775 GspD/PilQ family TSH58p_20730 16f7029b1c0a133f8cbe697094f687ca 482 PRINTS PR00811 Bacterial general secretion pathway protein D signature 252 276 6.1E-12 T 14-10-2018 IPR001775 GspD/PilQ family TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Gene3D G3DSA:3.30.559.30 1849 2092 1.9E-66 T 14-10-2018 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Gene3D G3DSA:3.30.300.30 427 527 1.6E-21 T 14-10-2018 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2292 2303 - T 14-10-2018 IPR020845 AMP-binding, conserved site TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 SMART SM00823 Phosphopantetheine attachment site 3707 3774 0.0017 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 SMART SM00823 Phosphopantetheine attachment site 2648 2717 5.7E-5 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 SMART SM00823 Phosphopantetheine attachment site 540 608 0.027 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 SMART SM00823 Phosphopantetheine attachment site 1594 1662 1.3E-4 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Gene3D G3DSA:3.30.559.30 2901 3159 4.7E-65 T 14-10-2018 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 SUPERFAMILY SSF52777 804 1064 4.78E-33 T 14-10-2018 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Gene3D G3DSA:3.30.559.30 802 1058 8.6E-61 T 14-10-2018 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Pfam PF00550 Phosphopantetheine attachment site 2650 2713 9.4E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Pfam PF00550 Phosphopantetheine attachment site 3708 3767 4.2E-9 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Pfam PF00550 Phosphopantetheine attachment site 542 604 2.6E-5 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Pfam PF00550 Phosphopantetheine attachment site 1596 1656 3.3E-12 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Pfam PF07993 Male sterility protein 3836 4079 1.1E-37 T 14-10-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 SUPERFAMILY SSF51735 3834 4104 4.09E-27 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 SUPERFAMILY SSF52777 2906 3165 1.33E-33 T 14-10-2018 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 SUPERFAMILY SSF56801 1064 1606 2.09E-138 T 14-10-2018 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3347 3358 - T 14-10-2018 IPR020845 AMP-binding, conserved site TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Gene3D G3DSA:3.40.50.720 3801 4202 3.1E-65 T 14-10-2018 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2672 2687 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 SUPERFAMILY SSF47336 534 605 1.16E-11 T 14-10-2018 IPR036736 ACP-like superfamily TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Gene3D G3DSA:3.30.300.30 1475 1581 4.7E-28 T 14-10-2018 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Gene3D G3DSA:3.30.300.30 2531 2634 5.6E-28 T 14-10-2018 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 SUPERFAMILY SSF52777 2731 2917 1.05E-25 T 14-10-2018 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 SUPERFAMILY SSF52777 1698 1864 4.0E-24 T 14-10-2018 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1234 1245 - T 14-10-2018 IPR020845 AMP-binding, conserved site TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1617 1632 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 SUPERFAMILY SSF56801 22 548 4.84E-129 T 14-10-2018 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2166 2561 1.1E-113 T 14-10-2018 IPR010071 Amino acid adenylation domain TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3222 3615 1.1E-110 T 14-10-2018 IPR010071 Amino acid adenylation domain TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1117 1505 6.7E-108 T 14-10-2018 IPR010071 Amino acid adenylation domain TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Gene3D G3DSA:3.40.50.12780 2137 2530 3.6E-113 T 14-10-2018 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 SUPERFAMILY SSF56801 3170 3718 2.49E-143 T 14-10-2018 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Gene3D G3DSA:3.40.50.12780 1085 1474 1.4E-113 T 14-10-2018 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Gene3D G3DSA:3.40.50.12780 24 426 9.8E-102 T 14-10-2018 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Gene3D G3DSA:3.40.50.12780 3191 3585 9.8E-111 T 14-10-2018 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 SUPERFAMILY SSF47336 2641 2713 3.14E-16 T 14-10-2018 IPR036736 ACP-like superfamily TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Gene3D G3DSA:3.30.559.10 2731 3102 4.7E-65 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Pfam PF13193 AMP-binding enzyme C-terminal domain 2545 2621 7.8E-11 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Pfam PF13193 AMP-binding enzyme C-terminal domain 3599 3675 2.0E-8 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Pfam PF13193 AMP-binding enzyme C-terminal domain 1489 1565 4.2E-9 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Gene3D G3DSA:3.30.559.10 1698 2050 1.9E-66 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 SUPERFAMILY SSF56801 2114 2660 1.31E-141 T 14-10-2018 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 SUPERFAMILY SSF47336 3699 3767 2.75E-13 T 14-10-2018 IPR036736 ACP-like superfamily TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Gene3D G3DSA:3.30.300.30 3586 3691 6.3E-31 T 14-10-2018 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Gene3D G3DSA:1.10.1200.10 2635 2719 4.2E-23 T 14-10-2018 IPR036736 ACP-like superfamily TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Gene3D G3DSA:1.10.1200.10 528 613 1.4E-17 T 14-10-2018 IPR036736 ACP-like superfamily TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Gene3D G3DSA:1.10.1200.10 3692 3779 5.9E-19 T 14-10-2018 IPR036736 ACP-like superfamily TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 SUPERFAMILY SSF47336 1588 1658 1.7E-14 T 14-10-2018 IPR036736 ACP-like superfamily TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 SUPERFAMILY SSF52777 621 817 4.34E-22 T 14-10-2018 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Gene3D G3DSA:1.10.1200.10 1582 1664 8.3E-22 T 14-10-2018 IPR036736 ACP-like superfamily TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Gene3D G3DSA:3.30.559.10 621 1001 8.6E-61 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Pfam PF00501 AMP-binding enzyme 1095 1480 9.0E-87 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Pfam PF00501 AMP-binding enzyme 3205 3591 2.0E-86 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Pfam PF00501 AMP-binding enzyme 2151 2536 5.9E-91 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Pfam PF00501 AMP-binding enzyme 34 432 3.6E-80 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 ProSitePatterns PS00455 Putative AMP-binding domain signature. 187 198 - T 14-10-2018 IPR020845 AMP-binding, conserved site TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Pfam PF00668 Condensation domain 621 1062 8.2E-35 T 14-10-2018 IPR001242 Condensation domain TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Pfam PF00668 Condensation domain 2731 3151 4.2E-48 T 14-10-2018 IPR001242 Condensation domain TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 Pfam PF00668 Condensation domain 1707 2092 2.9E-41 T 14-10-2018 IPR001242 Condensation domain TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3731 3746 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site TSH58p_00750 6332d987b9918efd251d34830bddf7eb 4204 SUPERFAMILY SSF52777 1854 2105 3.89E-34 T 14-10-2018 TSH58p_02820 7d711d168b5a9779245616aaa6437c30 753 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 139 202 3.5E-7 T 14-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 TSH58p_02820 7d711d168b5a9779245616aaa6437c30 753 Gene3D G3DSA:3.40.50.720 2 134 2.1E-30 T 14-10-2018 TSH58p_02820 7d711d168b5a9779245616aaa6437c30 753 SUPERFAMILY SSF51735 7 156 3.94E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_02820 7d711d168b5a9779245616aaa6437c30 753 Gene3D G3DSA:3.30.360.10 135 332 3.7E-37 T 14-10-2018 TSH58p_02820 7d711d168b5a9779245616aaa6437c30 753 SUPERFAMILY SSF55347 134 304 1.37E-23 T 14-10-2018 TSH58p_02820 7d711d168b5a9779245616aaa6437c30 753 Gene3D G3DSA:3.40.50.720 346 637 3.1E-57 T 14-10-2018 TSH58p_02820 7d711d168b5a9779245616aaa6437c30 753 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 126 1.5E-21 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 TSH58p_02820 7d711d168b5a9779245616aaa6437c30 753 SUPERFAMILY SSF51735 351 715 1.13E-55 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_02820 7d711d168b5a9779245616aaa6437c30 753 Pfam PF01370 NAD dependent epimerase/dehydratase family 356 572 6.8E-25 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TSH58p_02700 f7fbafd8a74d3e60a5a04b5efff14361 423 SUPERFAMILY SSF54966 3 133 2.88E-36 T 14-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TSH58p_02700 f7fbafd8a74d3e60a5a04b5efff14361 423 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 139 419 2.5E-78 T 14-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TSH58p_02700 f7fbafd8a74d3e60a5a04b5efff14361 423 ProSitePatterns PS00157 Ribulose bisphosphate carboxylase large chain active site. 181 189 - T 14-10-2018 IPR020878 Ribulose bisphosphate carboxylase, large chain, active site GO:0000287|GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TSH58p_02700 f7fbafd8a74d3e60a5a04b5efff14361 423 SUPERFAMILY SSF51649 133 420 6.15E-91 T 14-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TSH58p_02700 f7fbafd8a74d3e60a5a04b5efff14361 423 Gene3D G3DSA:3.20.20.110 134 422 1.9E-104 T 14-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TSH58p_02700 f7fbafd8a74d3e60a5a04b5efff14361 423 Gene3D G3DSA:3.30.70.150 1 133 4.0E-47 T 14-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TSH58p_02700 f7fbafd8a74d3e60a5a04b5efff14361 423 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 16 129 5.4E-7 T 14-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TSH58p_11265 c1bd0a39d2920e9886edf973eb7e68f2 336 SUPERFAMILY SSF53613 6 319 6.55E-77 T 14-10-2018 IPR029056 Ribokinase-like TSH58p_11265 c1bd0a39d2920e9886edf973eb7e68f2 336 Pfam PF00294 pfkB family carbohydrate kinase 58 317 2.0E-48 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB TSH58p_11265 c1bd0a39d2920e9886edf973eb7e68f2 336 Gene3D G3DSA:3.40.1190.20 13 315 4.1E-89 T 14-10-2018 IPR029056 Ribokinase-like TSH58p_11265 c1bd0a39d2920e9886edf973eb7e68f2 336 Gene3D G3DSA:3.30.1110.10 16 132 4.1E-89 T 14-10-2018 TSH58p_11265 c1bd0a39d2920e9886edf973eb7e68f2 336 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 273 286 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TSH58p_31975 bda3d3e15e6e8ad2f125ff33958827cb 317 SUPERFAMILY SSF53633 1 306 6.68E-71 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSH58p_31975 bda3d3e15e6e8ad2f125ff33958827cb 317 PRINTS PR01469 Bacterial carbamate kinase signature 71 89 6.0E-58 T 14-10-2018 TSH58p_31975 bda3d3e15e6e8ad2f125ff33958827cb 317 PRINTS PR01469 Bacterial carbamate kinase signature 103 122 6.0E-58 T 14-10-2018 TSH58p_31975 bda3d3e15e6e8ad2f125ff33958827cb 317 PRINTS PR01469 Bacterial carbamate kinase signature 174 192 6.0E-58 T 14-10-2018 TSH58p_31975 bda3d3e15e6e8ad2f125ff33958827cb 317 PRINTS PR01469 Bacterial carbamate kinase signature 41 60 6.0E-58 T 14-10-2018 TSH58p_31975 bda3d3e15e6e8ad2f125ff33958827cb 317 PRINTS PR01469 Bacterial carbamate kinase signature 263 278 6.0E-58 T 14-10-2018 TSH58p_31975 bda3d3e15e6e8ad2f125ff33958827cb 317 PRINTS PR01469 Bacterial carbamate kinase signature 151 170 6.0E-58 T 14-10-2018 TSH58p_31975 bda3d3e15e6e8ad2f125ff33958827cb 317 Pfam PF00696 Amino acid kinase family 1 285 5.7E-21 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TSH58p_31975 bda3d3e15e6e8ad2f125ff33958827cb 317 Gene3D G3DSA:3.40.1160.10 1 308 9.0E-104 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSH58p_31975 bda3d3e15e6e8ad2f125ff33958827cb 317 PIRSF PIRSF000723 1 308 2.1E-98 T 14-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 TSH58p_31975 bda3d3e15e6e8ad2f125ff33958827cb 317 TIGRFAM TIGR00746 arcC: carbamate kinase 1 306 1.3E-113 T 14-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 TSH58p_23635 b912865f8869c2e89016a239fc13e245 720 Gene3D G3DSA:1.20.1480.50 331 430 4.3E-16 T 14-10-2018 TSH58p_23635 b912865f8869c2e89016a239fc13e245 720 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 481 510 9.4E-19 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_23635 b912865f8869c2e89016a239fc13e245 720 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 587 616 9.4E-19 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_23635 b912865f8869c2e89016a239fc13e245 720 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 558 585 9.4E-19 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_23635 b912865f8869c2e89016a239fc13e245 720 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 536 681 2.6E-26 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_23635 b912865f8869c2e89016a239fc13e245 720 SUPERFAMILY SSF58104 400 713 6.15E-55 T 14-10-2018 TSH58p_23635 b912865f8869c2e89016a239fc13e245 720 SMART SM00283 460 714 1.5E-37 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_23635 b912865f8869c2e89016a239fc13e245 720 Pfam PF00672 HAMP domain 371 420 6.3E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_23635 b912865f8869c2e89016a239fc13e245 720 Gene3D G3DSA:1.10.287.950 479 716 5.4E-42 T 14-10-2018 TSH58p_23635 b912865f8869c2e89016a239fc13e245 720 SMART SM00304 371 424 2.6E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_23170 e8e58bcfd55b5fceef88c7206e15aa3d 506 SUPERFAMILY SSF53335 1 473 2.13E-77 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_23170 e8e58bcfd55b5fceef88c7206e15aa3d 506 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 135 149 6.9E-7 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 TSH58p_23170 e8e58bcfd55b5fceef88c7206e15aa3d 506 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 181 194 6.9E-7 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 TSH58p_23170 e8e58bcfd55b5fceef88c7206e15aa3d 506 Pfam PF00145 C-5 cytosine-specific DNA methylase 1 470 1.5E-57 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 TSH58p_23170 e8e58bcfd55b5fceef88c7206e15aa3d 506 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 1 218 1.9E-38 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 TSH58p_23170 e8e58bcfd55b5fceef88c7206e15aa3d 506 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 452 470 - T 14-10-2018 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 TSH58p_23170 e8e58bcfd55b5fceef88c7206e15aa3d 506 Gene3D G3DSA:3.40.50.150 1 241 1.2E-51 T 14-10-2018 TSH58p_23170 e8e58bcfd55b5fceef88c7206e15aa3d 506 Gene3D G3DSA:3.90.120.10 327 458 2.0E-21 T 14-10-2018 TSH58p_04185 43ccddb062a5c4e035c0c57810da9254 104 Pfam PF02625 XdhC and CoxI family 12 79 3.1E-28 T 14-10-2018 IPR003777 XdhC- CoxI TSH58p_02420 73e787a3dd9c9e1c3fb0147d9fc0e8b4 139 Gene3D G3DSA:2.20.25.10 1 44 1.2E-20 T 14-10-2018 TSH58p_02420 73e787a3dd9c9e1c3fb0147d9fc0e8b4 139 Pfam PF02566 OsmC-like protein 38 136 2.3E-17 T 14-10-2018 IPR003718 OsmC/Ohr family TSH58p_02420 73e787a3dd9c9e1c3fb0147d9fc0e8b4 139 SUPERFAMILY SSF82784 1 136 2.22E-42 T 14-10-2018 IPR036102 OsmC/Ohr superfamily TSH58p_02420 73e787a3dd9c9e1c3fb0147d9fc0e8b4 139 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 4 136 1.8E-56 T 14-10-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 TSH58p_02420 73e787a3dd9c9e1c3fb0147d9fc0e8b4 139 Gene3D G3DSA:3.30.300.20 45 138 4.1E-33 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta TSH58p_14655 bfe4847155ad47fc18b2fe71cfe64a25 213 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 10 192 3.3E-61 T 14-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 TSH58p_14655 bfe4847155ad47fc18b2fe71cfe64a25 213 Gene3D G3DSA:3.40.630.70 35 206 1.5E-62 T 14-10-2018 TSH58p_14655 bfe4847155ad47fc18b2fe71cfe64a25 213 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 213 84.17 T 14-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 TSH58p_14655 bfe4847155ad47fc18b2fe71cfe64a25 213 SUPERFAMILY SSF55729 4 197 1.91E-78 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_14655 bfe4847155ad47fc18b2fe71cfe64a25 213 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 8 178 3.0E-70 T 14-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 TSH58p_18905 2498b718e1d356e146c6c5f32af03920 311 SUPERFAMILY SSF53850 94 299 4.81E-35 T 14-10-2018 TSH58p_18905 2498b718e1d356e146c6c5f32af03920 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.6E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_18905 2498b718e1d356e146c6c5f32af03920 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.6E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_18905 2498b718e1d356e146c6c5f32af03920 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.6E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_18905 2498b718e1d356e146c6c5f32af03920 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 2.4E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_18905 2498b718e1d356e146c6c5f32af03920 311 Gene3D G3DSA:3.40.190.10 97 292 1.5E-63 T 14-10-2018 TSH58p_18905 2498b718e1d356e146c6c5f32af03920 311 SUPERFAMILY SSF46785 7 90 4.19E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_18905 2498b718e1d356e146c6c5f32af03920 311 Pfam PF03466 LysR substrate binding domain 92 297 2.9E-40 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_18905 2498b718e1d356e146c6c5f32af03920 311 Gene3D G3DSA:3.40.190.10 166 269 1.5E-63 T 14-10-2018 TSH58p_18905 2498b718e1d356e146c6c5f32af03920 311 Gene3D G3DSA:1.10.10.10 2 89 1.3E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_31030 10965fabd3a758e40c2df103c9abe803 309 Gene3D G3DSA:1.10.1040.10 172 303 1.1E-45 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSH58p_31030 10965fabd3a758e40c2df103c9abe803 309 Gene3D G3DSA:3.40.50.720 1 171 1.7E-55 T 14-10-2018 TSH58p_31030 10965fabd3a758e40c2df103c9abe803 309 SUPERFAMILY SSF48179 172 300 4.13E-41 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_31030 10965fabd3a758e40c2df103c9abe803 309 TIGRFAM TIGR01692 HIBADH: 3-hydroxyisobutyrate dehydrogenase 6 299 4.2E-110 T 14-10-2018 IPR011548 3-hydroxyisobutyrate dehydrogenase GO:0008442|GO:0051287|GO:0055114 KEGG: 00280+1.1.1.31|Reactome: R-HSA-70895 TSH58p_31030 10965fabd3a758e40c2df103c9abe803 309 PIRSF PIRSF000103 1 308 2.3E-82 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 TSH58p_31030 10965fabd3a758e40c2df103c9abe803 309 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 170 1.8E-48 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 TSH58p_31030 10965fabd3a758e40c2df103c9abe803 309 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 173 299 1.8E-37 T 14-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 TSH58p_31030 10965fabd3a758e40c2df103c9abe803 309 SUPERFAMILY SSF51735 1 170 2.06E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_15215 2c26ded3b233f1adc85854608a8b6d83 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 1.8E-58 T 14-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 TSH58p_15215 2c26ded3b233f1adc85854608a8b6d83 122 Gene3D G3DSA:2.40.150.20 1 122 6.6E-56 T 14-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 TSH58p_15215 2c26ded3b233f1adc85854608a8b6d83 122 SMART SM01374 1 122 3.3E-87 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TSH58p_15215 2c26ded3b233f1adc85854608a8b6d83 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 14-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15215 2c26ded3b233f1adc85854608a8b6d83 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 2.0E-56 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TSH58p_15215 2c26ded3b233f1adc85854608a8b6d83 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 28.442 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TSH58p_15215 2c26ded3b233f1adc85854608a8b6d83 122 SUPERFAMILY SSF50193 1 122 3.53E-53 T 14-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 TSH58p_10295 42860b06a08ed21e4178d3bfffbe84f7 382 SUPERFAMILY SSF48695 15 181 4.2E-51 T 14-10-2018 IPR036280 Multiheme cytochrome superfamily TSH58p_10295 42860b06a08ed21e4178d3bfffbe84f7 382 SUPERFAMILY SSF46626 304 379 4.56E-7 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_10295 42860b06a08ed21e4178d3bfffbe84f7 382 PIRSF PIRSF000014 5 382 4.2E-127 T 14-10-2018 IPR009154 Membrane-bound tetrahaem cytochrome TorC/YecK GO:0005506|GO:0009055|GO:0009276|GO:0016021|GO:0020037 TSH58p_10295 42860b06a08ed21e4178d3bfffbe84f7 382 Gene3D G3DSA:1.10.3820.10 11 185 1.9E-38 T 14-10-2018 IPR038266 NapC/NirT cytochrome c superfamily TSH58p_10295 42860b06a08ed21e4178d3bfffbe84f7 382 Pfam PF03264 NapC/NirT cytochrome c family, N-terminal region 16 180 1.5E-71 T 14-10-2018 IPR005126 NapC/NirT cytochrome c, N-terminal TSH58p_06255 797da49371d154dea4476198a461cd0e 487 Pfam PF13746 4Fe-4S dicluster domain 214 321 7.7E-41 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_06255 797da49371d154dea4476198a461cd0e 487 Gene3D G3DSA:2.60.40.10 360 484 6.6E-17 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_06255 797da49371d154dea4476198a461cd0e 487 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 357 484 9.3E-29 T 14-10-2018 IPR032879 FixG, C-terminal immunoglobulin-like domain TSH58p_06255 797da49371d154dea4476198a461cd0e 487 SUPERFAMILY SSF54862 100 358 1.02E-27 T 14-10-2018 TSH58p_06255 797da49371d154dea4476198a461cd0e 487 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 269 280 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_06255 797da49371d154dea4476198a461cd0e 487 Pfam PF12801 4Fe-4S binding domain 91 130 1.1E-8 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_06255 797da49371d154dea4476198a461cd0e 487 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 30 481 3.2E-149 T 14-10-2018 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021|GO:0055114 TSH58p_25700 906200abce175913a8da39f79eabe945 336 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 39 333 1.9E-94 T 14-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TSH58p_25700 906200abce175913a8da39f79eabe945 336 Gene3D G3DSA:3.40.50.10800 205 289 9.5E-112 T 14-10-2018 TSH58p_25700 906200abce175913a8da39f79eabe945 336 Gene3D G3DSA:3.40.50.10800 122 331 9.5E-112 T 14-10-2018 TSH58p_25700 906200abce175913a8da39f79eabe945 336 Gene3D G3DSA:3.40.50.10800 41 314 9.5E-112 T 14-10-2018 TSH58p_25700 906200abce175913a8da39f79eabe945 336 Pfam PF02445 Quinolinate synthetase A protein 42 332 2.9E-110 T 14-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TSH58p_25700 906200abce175913a8da39f79eabe945 336 SUPERFAMILY SSF142754 39 332 4.45E-108 T 14-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TSH58p_25700 906200abce175913a8da39f79eabe945 336 Hamap MF_00568 Quinolinate synthase A [nadA]. 37 333 44.763 T 14-10-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TSH58p_26135 77d8f02dc610faeb2cf32a33581c6f49 1022 Gene3D G3DSA:3.30.565.10 468 639 1.6E-50 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_26135 77d8f02dc610faeb2cf32a33581c6f49 1022 SMART SM00387 516 635 2.0E-36 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_26135 77d8f02dc610faeb2cf32a33581c6f49 1022 Gene3D G3DSA:1.10.287.130 370 467 2.7E-28 T 14-10-2018 TSH58p_26135 77d8f02dc610faeb2cf32a33581c6f49 1022 Gene3D G3DSA:3.40.50.2300 659 788 2.2E-36 T 14-10-2018 TSH58p_26135 77d8f02dc610faeb2cf32a33581c6f49 1022 SMART SM00388 404 469 4.6E-22 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_26135 77d8f02dc610faeb2cf32a33581c6f49 1022 Gene3D G3DSA:1.20.120.160 822 922 3.7E-12 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_26135 77d8f02dc610faeb2cf32a33581c6f49 1022 SUPERFAMILY SSF52172 666 794 7.97E-37 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_26135 77d8f02dc610faeb2cf32a33581c6f49 1022 SUPERFAMILY SSF47226 766 913 9.03E-17 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_26135 77d8f02dc610faeb2cf32a33581c6f49 1022 Pfam PF00512 His Kinase A (phospho-acceptor) domain 404 469 4.1E-19 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_26135 77d8f02dc610faeb2cf32a33581c6f49 1022 Pfam PF01627 Hpt domain 852 913 1.6E-7 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TSH58p_26135 77d8f02dc610faeb2cf32a33581c6f49 1022 SUPERFAMILY SSF55874 458 631 2.49E-44 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_26135 77d8f02dc610faeb2cf32a33581c6f49 1022 PRINTS PR00344 Bacterial sensor protein C-terminal signature 619 632 1.5E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_26135 77d8f02dc610faeb2cf32a33581c6f49 1022 PRINTS PR00344 Bacterial sensor protein C-terminal signature 595 613 1.5E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_26135 77d8f02dc610faeb2cf32a33581c6f49 1022 PRINTS PR00344 Bacterial sensor protein C-terminal signature 578 588 1.5E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_26135 77d8f02dc610faeb2cf32a33581c6f49 1022 PRINTS PR00344 Bacterial sensor protein C-terminal signature 560 574 1.5E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_26135 77d8f02dc610faeb2cf32a33581c6f49 1022 SUPERFAMILY SSF47384 389 469 1.88E-21 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_26135 77d8f02dc610faeb2cf32a33581c6f49 1022 Pfam PF00072 Response regulator receiver domain 670 783 6.0E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_26135 77d8f02dc610faeb2cf32a33581c6f49 1022 SMART SM00448 668 783 1.0E-35 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_26135 77d8f02dc610faeb2cf32a33581c6f49 1022 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 516 631 1.1E-27 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_16395 9fcb089892f1ffb54062b8da10a289a9 343 SUPERFAMILY SSF51735 10 265 9.19E-62 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_16395 9fcb089892f1ffb54062b8da10a289a9 343 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_16395 9fcb089892f1ffb54062b8da10a289a9 343 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.2E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_16395 9fcb089892f1ffb54062b8da10a289a9 343 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 1.2E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_16395 9fcb089892f1ffb54062b8da10a289a9 343 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 1.2E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_16395 9fcb089892f1ffb54062b8da10a289a9 343 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 4.6E-20 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_16395 9fcb089892f1ffb54062b8da10a289a9 343 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 4.6E-20 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_16395 9fcb089892f1ffb54062b8da10a289a9 343 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 4.6E-20 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_16395 9fcb089892f1ffb54062b8da10a289a9 343 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 4.6E-20 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_16395 9fcb089892f1ffb54062b8da10a289a9 343 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 4.6E-20 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_16395 9fcb089892f1ffb54062b8da10a289a9 343 Pfam PF00106 short chain dehydrogenase 13 201 1.3E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_16395 9fcb089892f1ffb54062b8da10a289a9 343 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 207 7.4E-4 T 14-10-2018 TSH58p_16395 9fcb089892f1ffb54062b8da10a289a9 343 Gene3D G3DSA:3.40.50.720 8 268 1.4E-60 T 14-10-2018 TSH58p_10315 b90b29350f701ff702611bdd574876e6 96 SMART SM00883 2 94 3.3E-61 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TSH58p_10315 b90b29350f701ff702611bdd574876e6 96 Gene3D G3DSA:2.30.33.40 1 96 1.9E-40 T 14-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 TSH58p_10315 b90b29350f701ff702611bdd574876e6 96 PRINTS PR00297 10kDa chaperonin signature 81 94 1.5E-34 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TSH58p_10315 b90b29350f701ff702611bdd574876e6 96 PRINTS PR00297 10kDa chaperonin signature 3 18 1.5E-34 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TSH58p_10315 b90b29350f701ff702611bdd574876e6 96 PRINTS PR00297 10kDa chaperonin signature 60 72 1.5E-34 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TSH58p_10315 b90b29350f701ff702611bdd574876e6 96 PRINTS PR00297 10kDa chaperonin signature 25 46 1.5E-34 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TSH58p_10315 b90b29350f701ff702611bdd574876e6 96 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 27.403 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TSH58p_10315 b90b29350f701ff702611bdd574876e6 96 Pfam PF00166 Chaperonin 10 Kd subunit 2 94 3.4E-37 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TSH58p_10315 b90b29350f701ff702611bdd574876e6 96 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 14-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 TSH58p_10315 b90b29350f701ff702611bdd574876e6 96 SUPERFAMILY SSF50129 1 95 2.64E-36 T 14-10-2018 IPR011032 GroES-like superfamily TSH58p_07825 0d7579268af1bf9c57cc6e1520e27d6b 201 SMART SM00986 15 193 5.7E-15 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSH58p_07825 0d7579268af1bf9c57cc6e1520e27d6b 201 SMART SM00987 15 193 5.7E-15 T 14-10-2018 TSH58p_07825 0d7579268af1bf9c57cc6e1520e27d6b 201 Pfam PF03167 Uracil DNA glycosylase superfamily 119 192 1.8E-7 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSH58p_07825 0d7579268af1bf9c57cc6e1520e27d6b 201 Pfam PF03167 Uracil DNA glycosylase superfamily 20 88 6.6E-16 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSH58p_07825 0d7579268af1bf9c57cc6e1520e27d6b 201 SUPERFAMILY SSF52141 20 193 1.18E-29 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSH58p_07825 0d7579268af1bf9c57cc6e1520e27d6b 201 Gene3D G3DSA:3.40.470.10 11 201 6.0E-41 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSH58p_28415 2a131d6219c9ba51dbc1cadb0e13478f 388 Gene3D G3DSA:1.10.150.80 196 291 6.7E-22 T 14-10-2018 TSH58p_28415 2a131d6219c9ba51dbc1cadb0e13478f 388 SUPERFAMILY SSF53098 2 203 5.2E-66 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily TSH58p_28415 2a131d6219c9ba51dbc1cadb0e13478f 388 Gene3D G3DSA:3.30.420.10 1 190 1.8E-61 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TSH58p_28415 2a131d6219c9ba51dbc1cadb0e13478f 388 SMART SM00474 1 170 1.2E-33 T 14-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 TSH58p_28415 2a131d6219c9ba51dbc1cadb0e13478f 388 SUPERFAMILY SSF47819 190 299 7.29E-27 T 14-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 TSH58p_28415 2a131d6219c9ba51dbc1cadb0e13478f 388 TIGRFAM TIGR01388 rnd: ribonuclease D 3 364 2.8E-130 T 14-10-2018 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 TSH58p_28415 2a131d6219c9ba51dbc1cadb0e13478f 388 SMART SM00341 208 289 1.1E-15 T 14-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 TSH58p_28415 2a131d6219c9ba51dbc1cadb0e13478f 388 Pfam PF01612 3'-5' exonuclease 3 169 1.6E-34 T 14-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 TSH58p_28415 2a131d6219c9ba51dbc1cadb0e13478f 388 Hamap MF_01899 Ribonuclease D [rnd]. 1 365 47.571 T 14-10-2018 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 TSH58p_28415 2a131d6219c9ba51dbc1cadb0e13478f 388 Pfam PF00570 HRDC domain 212 279 7.2E-20 T 14-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 TSH58p_28415 2a131d6219c9ba51dbc1cadb0e13478f 388 SUPERFAMILY SSF47819 300 368 2.62E-14 T 14-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 TSH58p_02380 2ac18c62089774b535e1e48af31c4f69 177 Gene3D G3DSA:2.60.120.10 103 157 8.8E-47 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_02380 2ac18c62089774b535e1e48af31c4f69 177 Gene3D G3DSA:2.60.120.10 1 102 8.8E-47 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_02380 2ac18c62089774b535e1e48af31c4f69 177 Pfam PF05962 HutD 1 158 1.3E-47 T 14-10-2018 IPR010282 Uncharacterised protein family HutD/Ves TSH58p_02380 2ac18c62089774b535e1e48af31c4f69 177 SUPERFAMILY SSF51182 1 159 1.42E-46 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_26930 aee85c9903b7342c027883b4f60f8174 1048 Gene3D G3DSA:2.60.60.40 149 270 1.7E-7 T 14-10-2018 TSH58p_26930 aee85c9903b7342c027883b4f60f8174 1048 Gene3D G3DSA:2.60.60.40 293 407 9.1E-7 T 14-10-2018 TSH58p_26930 aee85c9903b7342c027883b4f60f8174 1048 Pfam PF13229 Right handed beta helix region 685 825 4.7E-10 T 14-10-2018 IPR039448 Right handed beta helix domain TSH58p_26930 aee85c9903b7342c027883b4f60f8174 1048 Gene3D G3DSA:2.160.20.10 870 1017 7.3E-9 T 14-10-2018 IPR012334 Pectin lyase fold TSH58p_26930 aee85c9903b7342c027883b4f60f8174 1048 Gene3D G3DSA:2.160.20.10 655 830 6.4E-14 T 14-10-2018 IPR012334 Pectin lyase fold TSH58p_26930 aee85c9903b7342c027883b4f60f8174 1048 SUPERFAMILY SSF51126 786 1027 1.4E-17 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor TSH58p_26930 aee85c9903b7342c027883b4f60f8174 1048 SMART SM00710 854 891 1700.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_26930 aee85c9903b7342c027883b4f60f8174 1048 SMART SM00710 793 815 6.5 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_26930 aee85c9903b7342c027883b4f60f8174 1048 SMART SM00710 718 739 9900.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_26930 aee85c9903b7342c027883b4f60f8174 1048 SMART SM00710 693 717 1000.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_26930 aee85c9903b7342c027883b4f60f8174 1048 SMART SM00710 893 915 220.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_26930 aee85c9903b7342c027883b4f60f8174 1048 SMART SM00710 741 763 1600.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_26930 aee85c9903b7342c027883b4f60f8174 1048 SMART SM00710 822 849 470.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_26930 aee85c9903b7342c027883b4f60f8174 1048 SUPERFAMILY SSF51126 452 836 2.6E-18 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor TSH58p_26930 aee85c9903b7342c027883b4f60f8174 1048 Pfam PF16841 Ca-dependent carbohydrate-binding module xylan-binding 295 387 8.2E-32 T 14-10-2018 IPR031768 Carbohydrate binding module, xylan-binding domain MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSH58p_26930 aee85c9903b7342c027883b4f60f8174 1048 Pfam PF16841 Ca-dependent carbohydrate-binding module xylan-binding 153 243 2.6E-30 T 14-10-2018 IPR031768 Carbohydrate binding module, xylan-binding domain MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSH58p_26930 aee85c9903b7342c027883b4f60f8174 1048 Pfam PF16841 Ca-dependent carbohydrate-binding module xylan-binding 12 104 4.9E-27 T 14-10-2018 IPR031768 Carbohydrate binding module, xylan-binding domain MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSH58p_26930 aee85c9903b7342c027883b4f60f8174 1048 Gene3D G3DSA:2.160.20.10 429 594 2.5E-15 T 14-10-2018 IPR012334 Pectin lyase fold TSH58p_26035 8382e0fd407847db8e95f47eb6c28a89 384 PIRSF PIRSF000521 5 147 2.6E-7 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSH58p_26035 8382e0fd407847db8e95f47eb6c28a89 384 PIRSF PIRSF000521 157 383 4.3E-38 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSH58p_26035 8382e0fd407847db8e95f47eb6c28a89 384 SUPERFAMILY SSF53383 2 382 8.02E-122 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_26035 8382e0fd407847db8e95f47eb6c28a89 384 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 206 243 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSH58p_26035 8382e0fd407847db8e95f47eb6c28a89 384 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 1 378 1.2E-139 T 14-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 TSH58p_26035 8382e0fd407847db8e95f47eb6c28a89 384 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 1 383 67.569 T 14-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 TSH58p_26035 8382e0fd407847db8e95f47eb6c28a89 384 Gene3D G3DSA:3.90.1150.10 9 373 6.2E-137 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_26035 8382e0fd407847db8e95f47eb6c28a89 384 Pfam PF00202 Aminotransferase class-III 8 378 1.6E-111 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSH58p_26035 8382e0fd407847db8e95f47eb6c28a89 384 Gene3D G3DSA:3.40.640.10 43 288 6.2E-137 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_16910 fe9d262a23ab6206868f34041b57af28 451 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 389 417 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 TSH58p_16910 fe9d262a23ab6206868f34041b57af28 451 Gene3D G3DSA:2.160.10.10 251 426 3.5E-47 T 14-10-2018 TSH58p_16910 fe9d262a23ab6206868f34041b57af28 451 SUPERFAMILY SSF53448 7 254 1.17E-55 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_16910 fe9d262a23ab6206868f34041b57af28 451 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 6 438 37.828 T 14-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 TSH58p_16910 fe9d262a23ab6206868f34041b57af28 451 SUPERFAMILY SSF51161 263 424 4.18E-44 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily TSH58p_16910 fe9d262a23ab6206868f34041b57af28 451 Pfam PF12804 MobA-like NTP transferase domain 9 131 3.8E-24 T 14-10-2018 IPR025877 MobA-like NTP transferase TSH58p_16910 fe9d262a23ab6206868f34041b57af28 451 Gene3D G3DSA:3.90.550.10 1 250 2.2E-66 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_16910 fe9d262a23ab6206868f34041b57af28 451 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 382 414 1.6E-7 T 14-10-2018 IPR001451 Hexapeptide repeat TSH58p_16910 fe9d262a23ab6206868f34041b57af28 451 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 8 439 5.8E-150 T 14-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 TSH58p_16910 fe9d262a23ab6206868f34041b57af28 451 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 307 338 3.5E-6 T 14-10-2018 IPR001451 Hexapeptide repeat TSH58p_16910 fe9d262a23ab6206868f34041b57af28 451 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 268 301 2.8E-5 T 14-10-2018 IPR001451 Hexapeptide repeat TSH58p_13410 6263e0532b9badeb62268ccf41a2010f 367 SUPERFAMILY SSF53850 50 353 2.59E-65 T 14-10-2018 TSH58p_13410 6263e0532b9badeb62268ccf41a2010f 367 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 23 352 2.6E-84 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family TSH58p_13410 6263e0532b9badeb62268ccf41a2010f 367 Gene3D G3DSA:3.40.190.10 150 287 6.1E-94 T 14-10-2018 TSH58p_13410 6263e0532b9badeb62268ccf41a2010f 367 Gene3D G3DSA:3.40.190.10 52 352 6.1E-94 T 14-10-2018 TSH58p_13410 6263e0532b9badeb62268ccf41a2010f 367 Pfam PF16868 NMT1-like family 52 352 1.6E-101 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family TSH58p_18995 90f2757a4ba2559e162e0452f1a9b483 425 Hamap MF_00318 Enolase [eno]. 2 411 44.637 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_18995 90f2757a4ba2559e162e0452f1a9b483 425 PRINTS PR00148 Enolase signature 37 51 3.3E-48 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_18995 90f2757a4ba2559e162e0452f1a9b483 425 PRINTS PR00148 Enolase signature 363 380 3.3E-48 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_18995 90f2757a4ba2559e162e0452f1a9b483 425 PRINTS PR00148 Enolase signature 334 348 3.3E-48 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_18995 90f2757a4ba2559e162e0452f1a9b483 425 PRINTS PR00148 Enolase signature 107 123 3.3E-48 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_18995 90f2757a4ba2559e162e0452f1a9b483 425 PRINTS PR00148 Enolase signature 161 174 3.3E-48 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_18995 90f2757a4ba2559e162e0452f1a9b483 425 PRINTS PR00148 Enolase signature 311 322 3.3E-48 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_18995 90f2757a4ba2559e162e0452f1a9b483 425 ProSitePatterns PS00164 Enolase signature. 334 347 - T 14-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_18995 90f2757a4ba2559e162e0452f1a9b483 425 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 423 3.8E-129 T 14-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_18995 90f2757a4ba2559e162e0452f1a9b483 425 Gene3D G3DSA:3.20.20.120 128 425 1.3E-129 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TSH58p_18995 90f2757a4ba2559e162e0452f1a9b483 425 SUPERFAMILY SSF54826 3 138 8.17E-55 T 14-10-2018 TSH58p_18995 90f2757a4ba2559e162e0452f1a9b483 425 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 421 9.9E-205 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_18995 90f2757a4ba2559e162e0452f1a9b483 425 Pfam PF03952 Enolase, N-terminal domain 4 134 1.0E-58 T 14-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_18995 90f2757a4ba2559e162e0452f1a9b483 425 PIRSF PIRSF001400 1 424 3.0E-185 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_18995 90f2757a4ba2559e162e0452f1a9b483 425 SUPERFAMILY SSF51604 141 422 5.09E-126 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TSH58p_18995 90f2757a4ba2559e162e0452f1a9b483 425 SMART SM01193 4 134 8.8E-94 T 14-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_18995 90f2757a4ba2559e162e0452f1a9b483 425 Gene3D G3DSA:3.30.390.10 1 127 1.3E-56 T 14-10-2018 IPR029017 Enolase-like, N-terminal TSH58p_18995 90f2757a4ba2559e162e0452f1a9b483 425 SMART SM01192 139 425 6.1E-219 T 14-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_00610 9c84ac56e2d5da4dd47643aed7f28b9a 617 Pfam PF08448 PAS fold 277 390 1.1E-7 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_00610 9c84ac56e2d5da4dd47643aed7f28b9a 617 Pfam PF08448 PAS fold 16 128 2.7E-8 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_00610 9c84ac56e2d5da4dd47643aed7f28b9a 617 Gene3D G3DSA:3.30.450.20 264 401 2.1E-13 T 14-10-2018 TSH58p_00610 9c84ac56e2d5da4dd47643aed7f28b9a 617 SUPERFAMILY SSF55785 138 250 3.32E-20 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_00610 9c84ac56e2d5da4dd47643aed7f28b9a 617 Pfam PF00989 PAS fold 143 249 1.7E-11 T 14-10-2018 IPR013767 PAS fold GO:0006355 TSH58p_00610 9c84ac56e2d5da4dd47643aed7f28b9a 617 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 12 135 1.3E-7 T 14-10-2018 IPR000014 PAS domain TSH58p_00610 9c84ac56e2d5da4dd47643aed7f28b9a 617 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 139 259 1.7E-21 T 14-10-2018 IPR000014 PAS domain TSH58p_00610 9c84ac56e2d5da4dd47643aed7f28b9a 617 SMART SM00091 142 207 2.7E-8 T 14-10-2018 IPR000014 PAS domain TSH58p_00610 9c84ac56e2d5da4dd47643aed7f28b9a 617 SMART SM00091 10 76 0.0035 T 14-10-2018 IPR000014 PAS domain TSH58p_00610 9c84ac56e2d5da4dd47643aed7f28b9a 617 SUPERFAMILY SSF55785 248 366 3.32E-8 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_00610 9c84ac56e2d5da4dd47643aed7f28b9a 617 Gene3D G3DSA:3.30.450.20 8 134 8.0E-22 T 14-10-2018 TSH58p_00610 9c84ac56e2d5da4dd47643aed7f28b9a 617 SMART SM00387 506 602 9.7E-7 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_00610 9c84ac56e2d5da4dd47643aed7f28b9a 617 Gene3D G3DSA:3.30.450.20 140 263 1.1E-23 T 14-10-2018 TSH58p_00610 9c84ac56e2d5da4dd47643aed7f28b9a 617 Pfam PF07568 Histidine kinase 411 484 6.4E-23 T 14-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain TSH58p_00610 9c84ac56e2d5da4dd47643aed7f28b9a 617 Gene3D G3DSA:3.30.565.10 467 605 2.6E-24 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_00610 9c84ac56e2d5da4dd47643aed7f28b9a 617 SUPERFAMILY SSF55874 475 598 7.33E-12 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_00610 9c84ac56e2d5da4dd47643aed7f28b9a 617 SUPERFAMILY SSF55785 11 112 3.32E-15 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_00610 9c84ac56e2d5da4dd47643aed7f28b9a 617 SMART SM00086 212 252 0.0083 T 14-10-2018 IPR001610 PAC motif TSH58p_00610 9c84ac56e2d5da4dd47643aed7f28b9a 617 SMART SM00086 89 129 140.0 T 14-10-2018 IPR001610 PAC motif TSH58p_23645 ad044bccf35a7556e8c460afe7c5ac27 138 Gene3D G3DSA:3.40.50.2300 1 137 4.2E-28 T 14-10-2018 TSH58p_23645 ad044bccf35a7556e8c460afe7c5ac27 138 SMART SM00448 1 121 2.4E-16 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_23645 ad044bccf35a7556e8c460afe7c5ac27 138 Pfam PF00072 Response regulator receiver domain 2 121 3.0E-17 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_23645 ad044bccf35a7556e8c460afe7c5ac27 138 SUPERFAMILY SSF52172 2 124 3.56E-25 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_32405 4bf946c4dad9b19400aff5eee41536e9 230 Pfam PF01381 Helix-turn-helix 52 101 3.2E-14 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_32405 4bf946c4dad9b19400aff5eee41536e9 230 SUPERFAMILY SSF51182 118 225 7.34E-22 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_32405 4bf946c4dad9b19400aff5eee41536e9 230 SUPERFAMILY SSF47413 47 110 5.09E-17 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_32405 4bf946c4dad9b19400aff5eee41536e9 230 Gene3D G3DSA:1.10.260.40 46 109 1.8E-16 T 14-10-2018 TSH58p_32405 4bf946c4dad9b19400aff5eee41536e9 230 Gene3D G3DSA:2.60.120.10 118 226 1.4E-17 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_32405 4bf946c4dad9b19400aff5eee41536e9 230 SMART SM00530 51 106 4.5E-15 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_32405 4bf946c4dad9b19400aff5eee41536e9 230 Pfam PF07883 Cupin domain 175 226 2.0E-9 T 14-10-2018 IPR013096 Cupin 2, conserved barrel TSH58p_11195 96cdb18c8ac7281f7a05cdd844c2573c 478 Pfam PF02589 LUD domain 69 296 5.3E-51 T 14-10-2018 IPR003741 LUD domain TSH58p_11195 96cdb18c8ac7281f7a05cdd844c2573c 478 Gene3D G3DSA:3.40.50.10420 138 296 2.6E-17 T 14-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily TSH58p_11195 96cdb18c8ac7281f7a05cdd844c2573c 478 Pfam PF11870 Domain of unknown function (DUF3390) 399 470 1.3E-9 T 14-10-2018 IPR024569 4Fe-4S binding protein, C-terminal TSH58p_11195 96cdb18c8ac7281f7a05cdd844c2573c 478 SUPERFAMILY SSF100950 62 297 7.11E-41 T 14-10-2018 IPR037171 NagB/RpiA transferase-like TSH58p_11195 96cdb18c8ac7281f7a05cdd844c2573c 478 SUPERFAMILY SSF46548 275 394 2.09E-17 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSH58p_11195 96cdb18c8ac7281f7a05cdd844c2573c 478 Pfam PF13534 4Fe-4S dicluster domain 313 378 4.6E-7 T 14-10-2018 TSH58p_11195 96cdb18c8ac7281f7a05cdd844c2573c 478 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 314 325 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_11195 96cdb18c8ac7281f7a05cdd844c2573c 478 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 18 455 7.8E-140 T 14-10-2018 IPR004452 4Fe-4S binding protein GO:0019516 TSH58p_22000 0f6a5159245bb18e231af4b5388da116 519 Gene3D G3DSA:3.40.50.300 345 519 1.9E-31 T 14-10-2018 TSH58p_22000 0f6a5159245bb18e231af4b5388da116 519 Pfam PF13671 AAA domain 348 488 1.9E-22 T 14-10-2018 TSH58p_22000 0f6a5159245bb18e231af4b5388da116 519 SUPERFAMILY SSF52540 339 484 8.49E-20 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_22000 0f6a5159245bb18e231af4b5388da116 519 Pfam PF01636 Phosphotransferase enzyme family 124 293 1.3E-10 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase TSH58p_22000 0f6a5159245bb18e231af4b5388da116 519 SUPERFAMILY SSF56112 13 314 3.21E-21 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily TSH58p_21675 031d8f17f101594462f426b6fec6e362 212 SUPERFAMILY SSF47616 91 210 7.1E-26 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily TSH58p_21675 031d8f17f101594462f426b6fec6e362 212 Gene3D G3DSA:3.40.30.10 1 88 6.2E-25 T 14-10-2018 TSH58p_21675 031d8f17f101594462f426b6fec6e362 212 Pfam PF00043 Glutathione S-transferase, C-terminal domain 109 197 2.6E-12 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal TSH58p_21675 031d8f17f101594462f426b6fec6e362 212 Gene3D G3DSA:1.20.1050.10 92 200 1.1E-22 T 14-10-2018 TSH58p_21675 031d8f17f101594462f426b6fec6e362 212 SUPERFAMILY SSF52833 11 87 2.07E-21 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_21675 031d8f17f101594462f426b6fec6e362 212 Pfam PF02798 Glutathione S-transferase, N-terminal domain 10 84 2.2E-16 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 TSH58p_16695 7da6cf45c63c6f9b1402b907a77fe827 754 SUPERFAMILY SSF81296 158 214 5.32E-10 T 14-10-2018 IPR014756 Immunoglobulin E-set TSH58p_16695 7da6cf45c63c6f9b1402b907a77fe827 754 SUPERFAMILY SSF51011 647 752 1.1E-36 T 14-10-2018 TSH58p_16695 7da6cf45c63c6f9b1402b907a77fe827 754 SUPERFAMILY SSF51445 200 640 2.3E-117 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_16695 7da6cf45c63c6f9b1402b907a77fe827 754 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 121 752 45.994 T 14-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 TSH58p_16695 7da6cf45c63c6f9b1402b907a77fe827 754 Gene3D G3DSA:2.60.40.1180 647 753 8.3E-41 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta TSH58p_16695 7da6cf45c63c6f9b1402b907a77fe827 754 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 129 749 3.6E-295 T 14-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 TSH58p_16695 7da6cf45c63c6f9b1402b907a77fe827 754 PIRSF PIRSF000463 26 754 2.6E-294 T 14-10-2018 IPR037439 1,4-alpha-glucan-branching enzyme GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 TSH58p_16695 7da6cf45c63c6f9b1402b907a77fe827 754 Gene3D G3DSA:2.60.40.10 22 242 3.2E-70 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_16695 7da6cf45c63c6f9b1402b907a77fe827 754 Pfam PF00128 Alpha amylase, catalytic domain 300 370 3.6E-8 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSH58p_16695 7da6cf45c63c6f9b1402b907a77fe827 754 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 652 751 5.7E-25 T 14-10-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 TSH58p_16695 7da6cf45c63c6f9b1402b907a77fe827 754 Gene3D G3DSA:3.20.20.80 255 636 1.2E-168 T 14-10-2018 TSH58p_16695 7da6cf45c63c6f9b1402b907a77fe827 754 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 145 228 8.4E-23 T 14-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 TSH58p_16695 7da6cf45c63c6f9b1402b907a77fe827 754 SMART SM00642 272 641 1.1E-6 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSH58p_16695 7da6cf45c63c6f9b1402b907a77fe827 754 SUPERFAMILY SSF81296 33 134 2.1E-15 T 14-10-2018 IPR014756 Immunoglobulin E-set TSH58p_07055 a5b3cc2ed028c971355a379437c5844e 134 Pfam PF00072 Response regulator receiver domain 13 127 1.7E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_07055 a5b3cc2ed028c971355a379437c5844e 134 SUPERFAMILY SSF52172 10 132 1.27E-32 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_07055 a5b3cc2ed028c971355a379437c5844e 134 SMART SM00448 11 127 1.1E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_07055 a5b3cc2ed028c971355a379437c5844e 134 Gene3D G3DSA:3.40.50.2300 7 134 7.3E-31 T 14-10-2018 TSH58p_08820 8eb43be9ab61335fde48e21a8bfe85a3 534 SUPERFAMILY SSF110921 422 520 4.84E-19 T 14-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TSH58p_08820 8eb43be9ab61335fde48e21a8bfe85a3 534 SUPERFAMILY SSF51569 3 296 5.13E-78 T 14-10-2018 TSH58p_08820 8eb43be9ab61335fde48e21a8bfe85a3 534 Pfam PF00682 HMGL-like 6 255 1.1E-42 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 TSH58p_08820 8eb43be9ab61335fde48e21a8bfe85a3 534 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 6 527 3.3E-199 T 14-10-2018 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 TSH58p_08820 8eb43be9ab61335fde48e21a8bfe85a3 534 SMART SM00917 378 525 1.9E-35 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TSH58p_08820 8eb43be9ab61335fde48e21a8bfe85a3 534 Pfam PF08502 LeuA allosteric (dimerisation) domain 380 521 5.7E-27 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TSH58p_08820 8eb43be9ab61335fde48e21a8bfe85a3 534 Gene3D G3DSA:3.30.160.270 404 523 1.1E-6 T 14-10-2018 TSH58p_08820 8eb43be9ab61335fde48e21a8bfe85a3 534 Gene3D G3DSA:3.20.20.70 5 329 1.5E-102 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_08820 8eb43be9ab61335fde48e21a8bfe85a3 534 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 13 29 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TSH58p_00635 8c3ca96c1e5bf1657fff9afb860ce2e8 285 PRINTS PR00996 Glutamate methyltransferase family signature 239 262 1.3E-39 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_00635 8c3ca96c1e5bf1657fff9afb860ce2e8 285 PRINTS PR00996 Glutamate methyltransferase family signature 36 49 1.3E-39 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_00635 8c3ca96c1e5bf1657fff9afb860ce2e8 285 PRINTS PR00996 Glutamate methyltransferase family signature 75 87 1.3E-39 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_00635 8c3ca96c1e5bf1657fff9afb860ce2e8 285 PRINTS PR00996 Glutamate methyltransferase family signature 150 166 1.3E-39 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_00635 8c3ca96c1e5bf1657fff9afb860ce2e8 285 PRINTS PR00996 Glutamate methyltransferase family signature 220 234 1.3E-39 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_00635 8c3ca96c1e5bf1657fff9afb860ce2e8 285 PRINTS PR00996 Glutamate methyltransferase family signature 115 135 1.3E-39 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_00635 8c3ca96c1e5bf1657fff9afb860ce2e8 285 SMART SM00138 14 280 7.5E-91 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_00635 8c3ca96c1e5bf1657fff9afb860ce2e8 285 Gene3D G3DSA:1.10.155.10 5 80 1.5E-13 T 14-10-2018 IPR036804 Chemotaxis receptor methyltransferase CheR, N-terminal domain superfamily TSH58p_00635 8c3ca96c1e5bf1657fff9afb860ce2e8 285 Pfam PF03705 CheR methyltransferase, all-alpha domain 15 64 1.7E-13 T 14-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal TSH58p_00635 8c3ca96c1e5bf1657fff9afb860ce2e8 285 SUPERFAMILY SSF53335 82 274 5.38E-45 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_00635 8c3ca96c1e5bf1657fff9afb860ce2e8 285 Gene3D G3DSA:3.40.50.150 81 282 1.2E-57 T 14-10-2018 TSH58p_00635 8c3ca96c1e5bf1657fff9afb860ce2e8 285 Pfam PF01739 CheR methyltransferase, SAM binding domain 82 269 4.3E-56 T 14-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal TSH58p_00635 8c3ca96c1e5bf1657fff9afb860ce2e8 285 SUPERFAMILY SSF47757 10 81 7.85E-18 T 14-10-2018 TSH58p_23275 01ccdd574ae276d0c3bbadd3f8ce07db 313 Gene3D G3DSA:1.20.58.390 194 313 1.7E-13 T 14-10-2018 TSH58p_23275 01ccdd574ae276d0c3bbadd3f8ce07db 313 Gene3D G3DSA:2.70.170.10 86 192 1.1E-9 T 14-10-2018 IPR036734 Neurotransmitter-gated ion-channel ligand-binding domain superfamily GO:0005230|GO:0006811|GO:0016021 TSH58p_23275 01ccdd574ae276d0c3bbadd3f8ce07db 313 SUPERFAMILY SSF90112 207 307 2.75E-5 T 14-10-2018 IPR036719 Neurotransmitter-gated ion-channel transmembrane domain superfamily GO:0006811|GO:0016021 TSH58p_23275 01ccdd574ae276d0c3bbadd3f8ce07db 313 SUPERFAMILY SSF63712 17 191 2.22E-8 T 14-10-2018 IPR036734 Neurotransmitter-gated ion-channel ligand-binding domain superfamily GO:0005230|GO:0006811|GO:0016021 TSH58p_09240 f36d599b6b932564e43e9d39c9404800 189 Pfam PF17212 Tail tubular protein 11 168 6.9E-6 T 14-10-2018 IPR033767 Tail tubular protein Gp11 TSH58p_01530 66f0734c33077aa235688953cf598c30 397 SUPERFAMILY SSF53187 1 393 7.71E-69 T 14-10-2018 TSH58p_01530 66f0734c33077aa235688953cf598c30 397 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 10 391 7.1E-78 T 14-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 TSH58p_01530 66f0734c33077aa235688953cf598c30 397 SUPERFAMILY SSF55031 197 313 2.09E-16 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TSH58p_01530 66f0734c33077aa235688953cf598c30 397 Pfam PF01546 Peptidase family M20/M25/M40 73 390 2.6E-25 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 TSH58p_01530 66f0734c33077aa235688953cf598c30 397 Gene3D G3DSA:3.30.70.360 197 312 7.9E-104 T 14-10-2018 TSH58p_01530 66f0734c33077aa235688953cf598c30 397 PIRSF PIRSF001235 1 397 2.2E-103 T 14-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 TSH58p_01530 66f0734c33077aa235688953cf598c30 397 Gene3D G3DSA:3.40.630.10 24 388 7.9E-104 T 14-10-2018 TSH58p_18410 5c64e267159312b749f974bd26d8a045 327 Hamap MF_00956 GDP-L-fucose synthase [fcl]. 12 313 46.778 T 14-10-2018 IPR028614 GDP-L-fucose synthase/GDP-L-colitose synthase GO:0009226|GO:0016491 KEGG: 00051+1.1.1.271|KEGG: 00520+1.1.1.271|MetaCyc: PWY-66|Reactome: R-HSA-6787639 TSH58p_18410 5c64e267159312b749f974bd26d8a045 327 Gene3D G3DSA:3.90.25.10 176 311 2.2E-93 T 14-10-2018 TSH58p_18410 5c64e267159312b749f974bd26d8a045 327 SUPERFAMILY SSF51735 8 315 1.23E-72 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_18410 5c64e267159312b749f974bd26d8a045 327 Gene3D G3DSA:3.40.50.720 15 302 2.2E-93 T 14-10-2018 TSH58p_18410 5c64e267159312b749f974bd26d8a045 327 Pfam PF01370 NAD dependent epimerase/dehydratase family 16 245 5.7E-68 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TSH58p_20885 15d526af118f27a291936647c24231ab 199 Pfam PF04542 Sigma-70 region 2 37 103 1.0E-19 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_20885 15d526af118f27a291936647c24231ab 199 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 58 90 - T 14-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_20885 15d526af118f27a291936647c24231ab 199 SUPERFAMILY SSF88946 13 116 2.04E-29 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_20885 15d526af118f27a291936647c24231ab 199 SUPERFAMILY SSF88659 126 188 5.98E-14 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSH58p_20885 15d526af118f27a291936647c24231ab 199 Gene3D G3DSA:1.10.1740.10 11 126 6.3E-29 T 14-10-2018 TSH58p_20885 15d526af118f27a291936647c24231ab 199 Pfam PF08281 Sigma-70, region 4 132 181 1.2E-13 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_20885 15d526af118f27a291936647c24231ab 199 Gene3D G3DSA:1.10.10.10 127 189 4.8E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_20885 15d526af118f27a291936647c24231ab 199 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 32 187 2.9E-26 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TSH58p_27920 607a81ac5659e5ec01a382d2cd23cdbb 144 SMART SM00116 13 61 5.9E-7 T 14-10-2018 IPR000644 CBS domain TSH58p_27920 607a81ac5659e5ec01a382d2cd23cdbb 144 SMART SM00116 79 126 6.8E-12 T 14-10-2018 IPR000644 CBS domain TSH58p_27920 607a81ac5659e5ec01a382d2cd23cdbb 144 Gene3D G3DSA:3.10.580.10 1 142 3.2E-47 T 14-10-2018 TSH58p_27920 607a81ac5659e5ec01a382d2cd23cdbb 144 Pfam PF00571 CBS domain 12 61 1.3E-10 T 14-10-2018 IPR000644 CBS domain TSH58p_27920 607a81ac5659e5ec01a382d2cd23cdbb 144 Pfam PF00571 CBS domain 72 126 2.6E-13 T 14-10-2018 IPR000644 CBS domain TSH58p_27920 607a81ac5659e5ec01a382d2cd23cdbb 144 SUPERFAMILY SSF54631 9 141 2.91E-34 T 14-10-2018 TSH58p_31225 1bf91cd25bbafe18adeb9dfa88341e2f 287 SMART SM00419 173 221 1.3E-8 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_31225 1bf91cd25bbafe18adeb9dfa88341e2f 287 SMART SM00100 15 136 2.6E-9 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_31225 1bf91cd25bbafe18adeb9dfa88341e2f 287 Pfam PF13545 Crp-like helix-turn-helix domain 153 227 2.8E-15 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_31225 1bf91cd25bbafe18adeb9dfa88341e2f 287 Pfam PF00027 Cyclic nucleotide-binding domain 35 120 4.9E-13 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_31225 1bf91cd25bbafe18adeb9dfa88341e2f 287 Gene3D G3DSA:1.10.10.10 150 236 6.9E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_31225 1bf91cd25bbafe18adeb9dfa88341e2f 287 SUPERFAMILY SSF51206 8 140 3.14E-24 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like TSH58p_31225 1bf91cd25bbafe18adeb9dfa88341e2f 287 Gene3D G3DSA:2.60.120.10 30 147 1.6E-24 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_31225 1bf91cd25bbafe18adeb9dfa88341e2f 287 SUPERFAMILY SSF46785 151 231 4.71E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_07745 a1e9deb6e38b86024210a8381087c314 359 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 229 311 4.7E-34 T 14-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 TSH58p_07745 a1e9deb6e38b86024210a8381087c314 359 PIRSF PIRSF000089 20 353 2.8E-106 T 14-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 TSH58p_07745 a1e9deb6e38b86024210a8381087c314 359 Gene3D G3DSA:3.40.50.620 15 218 1.7E-66 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_07745 a1e9deb6e38b86024210a8381087c314 359 Pfam PF01012 Electron transfer flavoprotein domain 24 203 7.6E-43 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 TSH58p_07745 a1e9deb6e38b86024210a8381087c314 359 SUPERFAMILY SSF52467 229 347 6.07E-45 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TSH58p_07745 a1e9deb6e38b86024210a8381087c314 359 SMART SM00893 24 216 2.1E-44 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 TSH58p_07745 a1e9deb6e38b86024210a8381087c314 359 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 292 318 - T 14-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 TSH58p_07745 a1e9deb6e38b86024210a8381087c314 359 Gene3D G3DSA:3.40.50.1220 223 356 3.7E-50 T 14-10-2018 TSH58p_07745 a1e9deb6e38b86024210a8381087c314 359 SUPERFAMILY SSF52402 22 220 7.67E-53 T 14-10-2018 TSH58p_10805 286fc1bfa16033a6b0a3fee7e1b7dc2d 291 Pfam PF01564 Spermine/spermidine synthase domain 62 247 1.1E-52 T 14-10-2018 TSH58p_10805 286fc1bfa16033a6b0a3fee7e1b7dc2d 291 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 7 291 36.963 T 14-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TSH58p_10805 286fc1bfa16033a6b0a3fee7e1b7dc2d 291 TIGRFAM TIGR00417 speE: spermidine synthase 8 285 1.6E-93 T 14-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TSH58p_10805 286fc1bfa16033a6b0a3fee7e1b7dc2d 291 SUPERFAMILY SSF53335 7 290 1.48E-80 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_10805 286fc1bfa16033a6b0a3fee7e1b7dc2d 291 Gene3D G3DSA:2.30.140.10 4 56 5.0E-17 T 14-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TSH58p_10805 286fc1bfa16033a6b0a3fee7e1b7dc2d 291 Gene3D G3DSA:3.40.50.150 57 291 2.8E-72 T 14-10-2018 TSH58p_10805 286fc1bfa16033a6b0a3fee7e1b7dc2d 291 Pfam PF17284 Spermidine synthase tetramerisation domain 7 59 1.3E-11 T 14-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TSH58p_06390 8bd93822d6c473a9a54a2ccf80b7096d 235 SUPERFAMILY SSF52540 3 225 1.63E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_06390 8bd93822d6c473a9a54a2ccf80b7096d 235 Gene3D G3DSA:3.40.50.300 1 234 1.2E-58 T 14-10-2018 TSH58p_06390 8bd93822d6c473a9a54a2ccf80b7096d 235 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_06390 8bd93822d6c473a9a54a2ccf80b7096d 235 SMART SM00382 30 213 2.9E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_06390 8bd93822d6c473a9a54a2ccf80b7096d 235 Pfam PF00005 ABC transporter 22 164 7.9E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_22920 24a65ce8b750ba594720d6cd4d4c7363 479 Gene3D G3DSA:1.10.4100.10 42 435 9.6E-86 T 14-10-2018 TSH58p_22920 24a65ce8b750ba594720d6cd4d4c7363 479 SUPERFAMILY SSF103378 25 463 4.05E-92 T 14-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 TSH58p_22920 24a65ce8b750ba594720d6cd4d4c7363 479 Gene3D G3DSA:3.30.1330.120 286 418 9.6E-86 T 14-10-2018 TSH58p_22920 24a65ce8b750ba594720d6cd4d4c7363 479 Pfam PF03972 MmgE/PrpD family 28 458 4.5E-92 T 14-10-2018 IPR005656 MmgE/PrpD GO:0016829 TSH58p_25510 973a1955e5dc2c17bcad6931dae55977 411 PRINTS PR00839 V8 serine protease family signature 29 46 2.4E-10 T 14-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 TSH58p_25510 973a1955e5dc2c17bcad6931dae55977 411 PRINTS PR00839 V8 serine protease family signature 133 146 2.4E-10 T 14-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 TSH58p_25510 973a1955e5dc2c17bcad6931dae55977 411 PRINTS PR00839 V8 serine protease family signature 168 184 2.4E-10 T 14-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 TSH58p_25510 973a1955e5dc2c17bcad6931dae55977 411 Pfam PF13365 Trypsin-like peptidase domain 29 188 9.1E-14 T 14-10-2018 TSH58p_25510 973a1955e5dc2c17bcad6931dae55977 411 SUPERFAMILY SSF50494 9 204 8.42E-23 T 14-10-2018 IPR009003 Peptidase S1, PA clan TSH58p_25510 973a1955e5dc2c17bcad6931dae55977 411 SUPERFAMILY SSF51120 163 378 5.23E-14 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_25510 973a1955e5dc2c17bcad6931dae55977 411 Gene3D G3DSA:2.40.10.10 11 126 2.7E-26 T 14-10-2018 TSH58p_25510 973a1955e5dc2c17bcad6931dae55977 411 Gene3D G3DSA:2.150.10.10 214 392 8.0E-17 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_25510 973a1955e5dc2c17bcad6931dae55977 411 Gene3D G3DSA:2.40.10.10 8 198 2.7E-26 T 14-10-2018 TSH58p_24550 fc59f790e587f367173fb4d1d83c2b98 397 SUPERFAMILY SSF103473 3 380 9.42E-59 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_24550 fc59f790e587f367173fb4d1d83c2b98 397 Gene3D G3DSA:1.20.1250.20 2 378 1.3E-48 T 14-10-2018 TSH58p_24550 fc59f790e587f367173fb4d1d83c2b98 397 Pfam PF07690 Major Facilitator Superfamily 9 324 8.6E-38 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_27525 890dee8d00be41d7c20dd229b37076dc 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 2.6E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_27525 890dee8d00be41d7c20dd229b37076dc 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 2.6E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_27525 890dee8d00be41d7c20dd229b37076dc 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 2.6E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_27525 890dee8d00be41d7c20dd229b37076dc 317 Gene3D G3DSA:3.40.190.10 101 287 5.1E-60 T 14-10-2018 TSH58p_27525 890dee8d00be41d7c20dd229b37076dc 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 6.5E-22 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_27525 890dee8d00be41d7c20dd229b37076dc 317 SUPERFAMILY SSF46785 3 82 4.57E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_27525 890dee8d00be41d7c20dd229b37076dc 317 Pfam PF03466 LysR substrate binding domain 89 290 1.1E-38 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_27525 890dee8d00be41d7c20dd229b37076dc 317 SUPERFAMILY SSF53850 89 292 1.23E-38 T 14-10-2018 TSH58p_27525 890dee8d00be41d7c20dd229b37076dc 317 Gene3D G3DSA:3.40.190.10 162 260 5.1E-60 T 14-10-2018 TSH58p_27525 890dee8d00be41d7c20dd229b37076dc 317 Gene3D G3DSA:1.10.10.10 5 93 3.9E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_12885 7b25e3aeb45c45105935ed1a11ea110a 534 ProSitePatterns PS00510 Malate synthase signature. 264 279 - T 14-10-2018 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TSH58p_12885 7b25e3aeb45c45105935ed1a11ea110a 534 Gene3D G3DSA:3.20.20.360 2 408 1.1E-195 T 14-10-2018 TSH58p_12885 7b25e3aeb45c45105935ed1a11ea110a 534 Gene3D G3DSA:1.20.1220.12 410 529 5.4E-47 T 14-10-2018 TSH58p_12885 7b25e3aeb45c45105935ed1a11ea110a 534 Pfam PF01274 Malate synthase 10 530 4.1E-212 T 14-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TSH58p_12885 7b25e3aeb45c45105935ed1a11ea110a 534 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 21 529 5.5E-248 T 14-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TSH58p_12885 7b25e3aeb45c45105935ed1a11ea110a 534 PIRSF PIRSF001363 1 531 3.1E-250 T 14-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TSH58p_12885 7b25e3aeb45c45105935ed1a11ea110a 534 SUPERFAMILY SSF51645 8 531 1.28E-200 T 14-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TSH58p_30255 dbae827893883c08524374de6c8ada3c 717 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 78 715 3.0E-108 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 TSH58p_30255 dbae827893883c08524374de6c8ada3c 717 Gene3D G3DSA:2.40.170.20 189 717 8.5E-120 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily TSH58p_30255 dbae827893883c08524374de6c8ada3c 717 Pfam PF00593 TonB dependent receptor 250 716 7.7E-57 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel TSH58p_30255 dbae827893883c08524374de6c8ada3c 717 Gene3D G3DSA:2.170.130.10 52 188 1.5E-40 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily TSH58p_30255 dbae827893883c08524374de6c8ada3c 717 SUPERFAMILY SSF56935 27 717 1.8E-136 T 14-10-2018 TSH58p_30255 dbae827893883c08524374de6c8ada3c 717 Pfam PF07715 TonB-dependent Receptor Plug Domain 76 177 1.3E-24 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain TSH58p_32470 093f060525b0029e628cdeada3c1e6fe 1047 Gene3D G3DSA:1.20.1640.10 512 1020 0.0 T 14-10-2018 TSH58p_32470 093f060525b0029e628cdeada3c1e6fe 1047 SUPERFAMILY SSF82866 829 1024 1.96E-42 T 14-10-2018 TSH58p_32470 093f060525b0029e628cdeada3c1e6fe 1047 SUPERFAMILY SSF82714 184 274 1.96E-23 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_32470 093f060525b0029e628cdeada3c1e6fe 1047 Gene3D G3DSA:3.30.2090.10 180 277 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_32470 093f060525b0029e628cdeada3c1e6fe 1047 SUPERFAMILY SSF82693 136 332 4.36E-27 T 14-10-2018 TSH58p_32470 093f060525b0029e628cdeada3c1e6fe 1047 SUPERFAMILY SSF82693 669 854 1.18E-23 T 14-10-2018 TSH58p_32470 093f060525b0029e628cdeada3c1e6fe 1047 Pfam PF00873 AcrB/AcrD/AcrF family 3 1023 0.0 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_32470 093f060525b0029e628cdeada3c1e6fe 1047 SUPERFAMILY SSF82693 39 133 2.17E-26 T 14-10-2018 TSH58p_32470 093f060525b0029e628cdeada3c1e6fe 1047 PRINTS PR00702 Acriflavin resistance protein family signature 448 471 6.1E-92 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_32470 093f060525b0029e628cdeada3c1e6fe 1047 PRINTS PR00702 Acriflavin resistance protein family signature 551 568 6.1E-92 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_32470 093f060525b0029e628cdeada3c1e6fe 1047 PRINTS PR00702 Acriflavin resistance protein family signature 9 33 6.1E-92 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_32470 093f060525b0029e628cdeada3c1e6fe 1047 PRINTS PR00702 Acriflavin resistance protein family signature 338 361 6.1E-92 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_32470 093f060525b0029e628cdeada3c1e6fe 1047 PRINTS PR00702 Acriflavin resistance protein family signature 393 417 6.1E-92 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_32470 093f060525b0029e628cdeada3c1e6fe 1047 PRINTS PR00702 Acriflavin resistance protein family signature 365 386 6.1E-92 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_32470 093f060525b0029e628cdeada3c1e6fe 1047 PRINTS PR00702 Acriflavin resistance protein family signature 37 55 6.1E-92 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_32470 093f060525b0029e628cdeada3c1e6fe 1047 PRINTS PR00702 Acriflavin resistance protein family signature 619 633 6.1E-92 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_32470 093f060525b0029e628cdeada3c1e6fe 1047 PRINTS PR00702 Acriflavin resistance protein family signature 473 496 6.1E-92 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_32470 093f060525b0029e628cdeada3c1e6fe 1047 Gene3D G3DSA:3.30.70.1430 39 814 0.0 T 14-10-2018 TSH58p_32470 093f060525b0029e628cdeada3c1e6fe 1047 SUPERFAMILY SSF82714 719 802 2.75E-20 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_32470 093f060525b0029e628cdeada3c1e6fe 1047 Gene3D G3DSA:1.20.1640.10 9 511 0.0 T 14-10-2018 TSH58p_32470 093f060525b0029e628cdeada3c1e6fe 1047 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 3 1033 0.0 T 14-10-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0006855|GO:0015562|GO:0016021 TSH58p_32470 093f060525b0029e628cdeada3c1e6fe 1047 Gene3D G3DSA:3.30.70.1430 566 665 0.0 T 14-10-2018 TSH58p_32470 093f060525b0029e628cdeada3c1e6fe 1047 SUPERFAMILY SSF82866 298 501 1.57E-46 T 14-10-2018 TSH58p_32470 093f060525b0029e628cdeada3c1e6fe 1047 Gene3D G3DSA:3.30.70.1320 134 334 0.0 T 14-10-2018 TSH58p_32470 093f060525b0029e628cdeada3c1e6fe 1047 Gene3D G3DSA:3.30.70.1440 666 863 0.0 T 14-10-2018 TSH58p_32470 093f060525b0029e628cdeada3c1e6fe 1047 Gene3D G3DSA:3.30.2090.10 718 806 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_32470 093f060525b0029e628cdeada3c1e6fe 1047 SUPERFAMILY SSF82693 564 668 7.85E-30 T 14-10-2018 TSH58p_24075 b8add2fef501235ee84e7c005a8b9f4e 253 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 3 249 4.4E-94 T 14-10-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 TSH58p_24075 b8add2fef501235ee84e7c005a8b9f4e 253 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 6 20 - T 14-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TSH58p_24075 b8add2fef501235ee84e7c005a8b9f4e 253 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 76 109 - T 14-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TSH58p_24075 b8add2fef501235ee84e7c005a8b9f4e 253 Gene3D G3DSA:3.30.950.10 111 230 2.5E-43 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 TSH58p_24075 b8add2fef501235ee84e7c005a8b9f4e 253 Gene3D G3DSA:3.40.1010.10 1 110 3.7E-28 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 TSH58p_24075 b8add2fef501235ee84e7c005a8b9f4e 253 SUPERFAMILY SSF53790 2 247 7.46E-62 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 TSH58p_24075 b8add2fef501235ee84e7c005a8b9f4e 253 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 208 1.6E-40 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 TSH58p_08700 570a0a9ea929078fde1c43ce8d536548 106 Pfam PF07345 Domain of unknown function (DUF1476) 1 102 2.3E-37 T 14-10-2018 IPR009945 Protein of unknown function DUF1476 TSH58p_08700 570a0a9ea929078fde1c43ce8d536548 106 PIRSF PIRSF031780 1 106 3.9E-31 T 14-10-2018 IPR009945 Protein of unknown function DUF1476 TSH58p_08700 570a0a9ea929078fde1c43ce8d536548 106 Gene3D G3DSA:1.10.790.20 1 106 1.7E-34 T 14-10-2018 TSH58p_01210 acb87189a10b8d8514979b4b61418d9b 295 Gene3D G3DSA:3.40.50.20 7 121 7.6E-24 T 14-10-2018 TSH58p_01210 acb87189a10b8d8514979b4b61418d9b 295 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 9 286 2.4E-47 T 14-10-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 TSH58p_01210 acb87189a10b8d8514979b4b61418d9b 295 Gene3D G3DSA:3.30.470.80 186 293 1.5E-34 T 14-10-2018 TSH58p_01210 acb87189a10b8d8514979b4b61418d9b 295 SUPERFAMILY SSF56059 108 292 1.73E-39 T 14-10-2018 TSH58p_01210 acb87189a10b8d8514979b4b61418d9b 295 Pfam PF08443 RimK-like ATP-grasp domain 106 286 2.6E-20 T 14-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 TSH58p_32375 2171fd4d500ed187e09f4b25823ed7d3 254 SMART SM00382 30 224 1.5E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_32375 2171fd4d500ed187e09f4b25823ed7d3 254 Gene3D G3DSA:3.40.50.300 2 253 4.4E-75 T 14-10-2018 TSH58p_32375 2171fd4d500ed187e09f4b25823ed7d3 254 SUPERFAMILY SSF52540 6 246 3.03E-75 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_32375 2171fd4d500ed187e09f4b25823ed7d3 254 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_32375 2171fd4d500ed187e09f4b25823ed7d3 254 PIRSF PIRSF039085 2 252 8.4E-109 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 TSH58p_32375 2171fd4d500ed187e09f4b25823ed7d3 254 Pfam PF00005 ABC transporter 21 176 2.5E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_20510 00e9bd629e8ad67606cb8458e6494bf7 576 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 508 519 - T 14-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_20510 00e9bd629e8ad67606cb8458e6494bf7 576 Pfam PF10531 SLBB domain 410 458 1.3E-8 T 14-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_20510 00e9bd629e8ad67606cb8458e6494bf7 576 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 43 180 1.6E-23 T 14-10-2018 TSH58p_20510 00e9bd629e8ad67606cb8458e6494bf7 576 SUPERFAMILY SSF140490 492 573 8.11E-25 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_20510 00e9bd629e8ad67606cb8458e6494bf7 576 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 497 572 3.7E-21 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_20510 00e9bd629e8ad67606cb8458e6494bf7 576 Gene3D G3DSA:3.10.20.600 398 492 1.3E-25 T 14-10-2018 TSH58p_20510 00e9bd629e8ad67606cb8458e6494bf7 576 SMART SM00928 495 540 2.6E-15 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_20510 00e9bd629e8ad67606cb8458e6494bf7 576 Gene3D G3DSA:1.10.10.1590 37 102 2.4E-6 T 14-10-2018 TSH58p_20510 00e9bd629e8ad67606cb8458e6494bf7 576 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 333 348 - T 14-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_20510 00e9bd629e8ad67606cb8458e6494bf7 576 Gene3D G3DSA:3.40.50.11540 228 397 1.7E-69 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_20510 00e9bd629e8ad67606cb8458e6494bf7 576 SUPERFAMILY SSF142019 189 405 3.53E-72 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_20510 00e9bd629e8ad67606cb8458e6494bf7 576 SUPERFAMILY SSF142984 407 490 6.02E-21 T 14-10-2018 TSH58p_20510 00e9bd629e8ad67606cb8458e6494bf7 576 Gene3D G3DSA:3.40.30.10 110 181 2.6E-10 T 14-10-2018 TSH58p_20510 00e9bd629e8ad67606cb8458e6494bf7 576 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 226 384 1.7E-43 T 14-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_20510 00e9bd629e8ad67606cb8458e6494bf7 576 SUPERFAMILY SSF52833 35 199 7.16E-33 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_20510 00e9bd629e8ad67606cb8458e6494bf7 576 Gene3D G3DSA:1.20.1440.230 493 576 2.1E-22 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05865 da83b3715c0b893ce106209b16842dff 102 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 3 102 19.608 T 14-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 TSH58p_05865 da83b3715c0b893ce106209b16842dff 102 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 8 97 1.1E-23 T 14-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like TSH58p_31255 48b9a9cb0d93e464b30b97183e39c571 313 SUPERFAMILY SSF52402 39 184 1.93E-8 T 14-10-2018 TSH58p_31255 48b9a9cb0d93e464b30b97183e39c571 313 PRINTS PR01438 Universal stress protein signature 273 285 2.2E-5 T 14-10-2018 IPR006015 Universal stress protein A TSH58p_31255 48b9a9cb0d93e464b30b97183e39c571 313 PRINTS PR01438 Universal stress protein signature 291 313 2.2E-5 T 14-10-2018 IPR006015 Universal stress protein A TSH58p_31255 48b9a9cb0d93e464b30b97183e39c571 313 Pfam PF00582 Universal stress protein family 193 313 5.5E-8 T 14-10-2018 IPR006016 UspA TSH58p_31255 48b9a9cb0d93e464b30b97183e39c571 313 SUPERFAMILY SSF52402 191 313 2.26E-17 T 14-10-2018 TSH58p_31255 48b9a9cb0d93e464b30b97183e39c571 313 Gene3D G3DSA:3.40.50.12370 44 313 1.6E-28 T 14-10-2018 TSH58p_14135 1f8f257392c0a16db6742e3fa3197b4b 766 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 394 516 1.9E-8 T 14-10-2018 IPR000014 PAS domain TSH58p_14135 1f8f257392c0a16db6742e3fa3197b4b 766 Gene3D G3DSA:3.30.450.20 384 518 8.4E-17 T 14-10-2018 TSH58p_14135 1f8f257392c0a16db6742e3fa3197b4b 766 Gene3D G3DSA:3.30.450.350 80 304 1.6E-8 T 14-10-2018 TSH58p_14135 1f8f257392c0a16db6742e3fa3197b4b 766 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 639 744 1.6E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_14135 1f8f257392c0a16db6742e3fa3197b4b 766 SUPERFAMILY SSF55785 386 507 7.61E-15 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_14135 1f8f257392c0a16db6742e3fa3197b4b 766 Gene3D G3DSA:3.30.565.10 593 746 2.0E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_14135 1f8f257392c0a16db6742e3fa3197b4b 766 SMART SM00388 529 594 2.9E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_14135 1f8f257392c0a16db6742e3fa3197b4b 766 SMART SM00387 638 749 5.0E-26 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_14135 1f8f257392c0a16db6742e3fa3197b4b 766 SUPERFAMILY SSF55874 583 745 2.23E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_14135 1f8f257392c0a16db6742e3fa3197b4b 766 Pfam PF08448 PAS fold 404 508 1.2E-10 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_14135 1f8f257392c0a16db6742e3fa3197b4b 766 Gene3D G3DSA:1.10.287.130 519 592 1.0E-13 T 14-10-2018 TSH58p_14135 1f8f257392c0a16db6742e3fa3197b4b 766 PRINTS PR00344 Bacterial sensor protein C-terminal signature 709 727 2.3E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_14135 1f8f257392c0a16db6742e3fa3197b4b 766 PRINTS PR00344 Bacterial sensor protein C-terminal signature 733 746 2.3E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_14135 1f8f257392c0a16db6742e3fa3197b4b 766 PRINTS PR00344 Bacterial sensor protein C-terminal signature 674 688 2.3E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_14135 1f8f257392c0a16db6742e3fa3197b4b 766 PRINTS PR00344 Bacterial sensor protein C-terminal signature 692 702 2.3E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_14135 1f8f257392c0a16db6742e3fa3197b4b 766 SUPERFAMILY SSF47384 514 595 2.55E-13 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_14135 1f8f257392c0a16db6742e3fa3197b4b 766 Pfam PF03924 CHASE domain 80 288 4.0E-27 T 14-10-2018 IPR006189 CHASE domain TSH58p_14135 1f8f257392c0a16db6742e3fa3197b4b 766 Pfam PF00512 His Kinase A (phospho-acceptor) domain 529 594 1.6E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_14135 1f8f257392c0a16db6742e3fa3197b4b 766 SMART SM01079 76 296 3.7E-15 T 14-10-2018 IPR006189 CHASE domain TSH58p_28195 781f3f3a476f5713c75777b460effdca 453 Gene3D G3DSA:1.10.287.130 201 309 1.7E-20 T 14-10-2018 TSH58p_28195 781f3f3a476f5713c75777b460effdca 453 SUPERFAMILY SSF47384 234 306 2.35E-13 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_28195 781f3f3a476f5713c75777b460effdca 453 Gene3D G3DSA:3.30.565.10 310 453 4.4E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_28195 781f3f3a476f5713c75777b460effdca 453 Pfam PF00672 HAMP domain 197 246 1.0E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_28195 781f3f3a476f5713c75777b460effdca 453 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 351 452 2.2E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_28195 781f3f3a476f5713c75777b460effdca 453 SMART SM00304 197 249 4.6E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_28195 781f3f3a476f5713c75777b460effdca 453 SMART SM00388 250 308 3.5E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_28195 781f3f3a476f5713c75777b460effdca 453 SUPERFAMILY SSF55874 301 453 1.96E-32 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_28195 781f3f3a476f5713c75777b460effdca 453 SMART SM00387 346 453 9.0E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_28195 781f3f3a476f5713c75777b460effdca 453 Pfam PF00512 His Kinase A (phospho-acceptor) domain 251 306 3.6E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_28195 781f3f3a476f5713c75777b460effdca 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 433 4.8E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_28195 781f3f3a476f5713c75777b460effdca 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 380 394 4.8E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_28195 781f3f3a476f5713c75777b460effdca 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 408 4.8E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_28195 781f3f3a476f5713c75777b460effdca 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 452 4.8E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_09885 ca2fbc0dd4082ecd999232e804291177 534 SMART SM00851 29 141 7.1E-51 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain TSH58p_09885 ca2fbc0dd4082ecd999232e804291177 534 SMART SM00798 146 459 1.7E-209 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSH58p_09885 ca2fbc0dd4082ecd999232e804291177 534 Gene3D G3DSA:3.40.140.20 392 534 1.6E-55 T 14-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSH58p_09885 ca2fbc0dd4082ecd999232e804291177 534 Gene3D G3DSA:3.40.50.1380 10 209 6.9E-84 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily TSH58p_09885 ca2fbc0dd4082ecd999232e804291177 534 Gene3D G3DSA:3.40.140.20 216 370 2.8E-58 T 14-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSH58p_09885 ca2fbc0dd4082ecd999232e804291177 534 SUPERFAMILY SSF52335 17 207 6.72E-67 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily TSH58p_09885 ca2fbc0dd4082ecd999232e804291177 534 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 19 534 1.0E-210 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSH58p_09885 ca2fbc0dd4082ecd999232e804291177 534 Pfam PF02142 MGS-like domain 29 140 1.4E-24 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain TSH58p_09885 ca2fbc0dd4082ecd999232e804291177 534 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 17 534 44.525 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSH58p_09885 ca2fbc0dd4082ecd999232e804291177 534 PIRSF PIRSF000414 13 534 8.0E-214 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSH58p_09885 ca2fbc0dd4082ecd999232e804291177 534 Pfam PF01808 AICARFT/IMPCHase bienzyme 146 458 3.0E-121 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSH58p_09885 ca2fbc0dd4082ecd999232e804291177 534 SUPERFAMILY SSF53927 222 534 5.72E-130 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TSH58p_19120 33943b9f8890caccb46d3bece6e47020 410 SUPERFAMILY SSF117143 82 370 3.27E-56 T 14-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like TSH58p_19120 33943b9f8890caccb46d3bece6e47020 410 Pfam PF00460 Flagella basal body rod protein 7 37 1.1E-8 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 TSH58p_19120 33943b9f8890caccb46d3bece6e47020 410 Pfam PF07559 Flagellar basal body protein FlaE 186 280 4.5E-9 T 14-10-2018 IPR011491 Flagellar hook protein FlgE TSH58p_19120 33943b9f8890caccb46d3bece6e47020 410 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 331 408 2.1E-16 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain TSH58p_19120 33943b9f8890caccb46d3bece6e47020 410 Gene3D G3DSA:2.60.98.20 166 285 3.4E-8 T 14-10-2018 IPR037058 Flagellar hook protein FlgE superfamily TSH58p_19120 33943b9f8890caccb46d3bece6e47020 410 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 14-10-2018 IPR019776 Flagellar basal body rod protein, conserved site TSH58p_19120 33943b9f8890caccb46d3bece6e47020 410 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 5 391 2.5E-84 T 14-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G TSH58p_31355 df195c181da95a664db08633003a74d0 301 Pfam PF02195 ParB-like nuclease domain 43 127 1.0E-17 T 14-10-2018 IPR003115 ParB/Sulfiredoxin TSH58p_31355 df195c181da95a664db08633003a74d0 301 SUPERFAMILY SSF109709 123 227 7.19E-18 T 14-10-2018 TSH58p_31355 df195c181da95a664db08633003a74d0 301 Gene3D G3DSA:3.90.1530.30 55 118 4.1E-20 T 14-10-2018 TSH58p_31355 df195c181da95a664db08633003a74d0 301 SUPERFAMILY SSF110849 33 134 1.34E-22 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily TSH58p_31355 df195c181da95a664db08633003a74d0 301 Gene3D G3DSA:1.10.10.2830 119 232 4.8E-19 T 14-10-2018 TSH58p_31355 df195c181da95a664db08633003a74d0 301 SMART SM00470 42 130 2.3E-24 T 14-10-2018 IPR003115 ParB/Sulfiredoxin TSH58p_31355 df195c181da95a664db08633003a74d0 301 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 41 193 1.1E-37 T 14-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 TSH58p_11150 8931abced13195a8dafd298e6324252d 207 Gene3D G3DSA:3.30.230.40 98 205 7.1E-42 T 14-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 TSH58p_11150 8931abced13195a8dafd298e6324252d 207 SUPERFAMILY SSF54211 10 94 6.96E-33 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSH58p_11150 8931abced13195a8dafd298e6324252d 207 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 164 176 - T 14-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 TSH58p_11150 8931abced13195a8dafd298e6324252d 207 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 10 203 43.65 T 14-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 TSH58p_11150 8931abced13195a8dafd298e6324252d 207 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 39 182 1.7E-66 T 14-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 TSH58p_11150 8931abced13195a8dafd298e6324252d 207 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 69 82 - T 14-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 TSH58p_11150 8931abced13195a8dafd298e6324252d 207 SUPERFAMILY SSF54211 96 186 6.83E-38 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSH58p_11150 8931abced13195a8dafd298e6324252d 207 Gene3D G3DSA:3.30.230.40 1 97 8.8E-37 T 14-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 TSH58p_26815 a86e7cdae1c3c08327666f308c62d727 328 SUPERFAMILY SSF51735 1 309 1.89E-84 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_26815 a86e7cdae1c3c08327666f308c62d727 328 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 12 304 2.5E-74 T 14-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 TSH58p_26815 a86e7cdae1c3c08327666f308c62d727 328 Gene3D G3DSA:3.30.1780.10 6 310 8.2E-91 T 14-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 TSH58p_26815 a86e7cdae1c3c08327666f308c62d727 328 Gene3D G3DSA:3.40.50.720 124 293 8.2E-91 T 14-10-2018 TSH58p_26815 a86e7cdae1c3c08327666f308c62d727 328 PIRSF PIRSF001439 1 320 1.6E-83 T 14-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 TSH58p_07510 01272ed6a9f270b60c5415e9235bda78 314 PIRSF PIRSF018455 9 303 3.5E-98 T 14-10-2018 IPR005073 Peptidase M74, penicillin-insensitive murein endopeptidase GO:0004252|GO:0006508|GO:0030288 TSH58p_07510 01272ed6a9f270b60c5415e9235bda78 314 SUPERFAMILY SSF55166 45 296 7.22E-87 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSH58p_07510 01272ed6a9f270b60c5415e9235bda78 314 Pfam PF03411 Penicillin-insensitive murein endopeptidase 59 294 3.1E-92 T 14-10-2018 IPR005073 Peptidase M74, penicillin-insensitive murein endopeptidase GO:0004252|GO:0006508|GO:0030288 TSH58p_07510 01272ed6a9f270b60c5415e9235bda78 314 Gene3D G3DSA:3.30.1380.10 43 298 5.0E-90 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSH58p_16025 2aa198924d93de1a8b5e75c0a2f8baef 286 Gene3D G3DSA:1.10.287.90 28 123 7.3E-36 T 14-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16025 2aa198924d93de1a8b5e75c0a2f8baef 286 Gene3D G3DSA:2.60.40.420 124 259 1.1E-61 T 14-10-2018 IPR008972 Cupredoxin TSH58p_16025 2aa198924d93de1a8b5e75c0a2f8baef 286 PRINTS PR01166 Cytochrome c oxidase subunit II signature 210 227 9.0E-57 T 14-10-2018 TSH58p_16025 2aa198924d93de1a8b5e75c0a2f8baef 286 PRINTS PR01166 Cytochrome c oxidase subunit II signature 123 142 9.0E-57 T 14-10-2018 TSH58p_16025 2aa198924d93de1a8b5e75c0a2f8baef 286 PRINTS PR01166 Cytochrome c oxidase subunit II signature 166 187 9.0E-57 T 14-10-2018 TSH58p_16025 2aa198924d93de1a8b5e75c0a2f8baef 286 PRINTS PR01166 Cytochrome c oxidase subunit II signature 89 101 9.0E-57 T 14-10-2018 TSH58p_16025 2aa198924d93de1a8b5e75c0a2f8baef 286 PRINTS PR01166 Cytochrome c oxidase subunit II signature 190 210 9.0E-57 T 14-10-2018 TSH58p_16025 2aa198924d93de1a8b5e75c0a2f8baef 286 PRINTS PR01166 Cytochrome c oxidase subunit II signature 228 245 9.0E-57 T 14-10-2018 TSH58p_16025 2aa198924d93de1a8b5e75c0a2f8baef 286 PRINTS PR01166 Cytochrome c oxidase subunit II signature 101 121 9.0E-57 T 14-10-2018 TSH58p_16025 2aa198924d93de1a8b5e75c0a2f8baef 286 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 191 239 - T 14-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16025 2aa198924d93de1a8b5e75c0a2f8baef 286 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 127 246 2.6E-58 T 14-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16025 2aa198924d93de1a8b5e75c0a2f8baef 286 SUPERFAMILY SSF49503 123 260 4.51E-59 T 14-10-2018 IPR008972 Cupredoxin TSH58p_16025 2aa198924d93de1a8b5e75c0a2f8baef 286 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 40 256 4.5E-62 T 14-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16025 2aa198924d93de1a8b5e75c0a2f8baef 286 SUPERFAMILY SSF81464 27 121 3.43E-30 T 14-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16025 2aa198924d93de1a8b5e75c0a2f8baef 286 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 29 115 5.7E-24 T 14-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_24710 1353cf0d53073ecc90323c900ef80fee 833 SUPERFAMILY SSF48452 12 288 7.11E-45 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_24710 1353cf0d53073ecc90323c900ef80fee 833 Pfam PF13374 Tetratricopeptide repeat 247 276 3.9E-4 T 14-10-2018 TSH58p_24710 1353cf0d53073ecc90323c900ef80fee 833 Gene3D G3DSA:1.25.40.10 282 414 1.1E-16 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_24710 1353cf0d53073ecc90323c900ef80fee 833 Pfam PF13844 Glycosyl transferase family 41 630 821 6.4E-48 T 14-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 TSH58p_24710 1353cf0d53073ecc90323c900ef80fee 833 Pfam PF13844 Glycosyl transferase family 41 469 619 1.5E-40 T 14-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 TSH58p_24710 1353cf0d53073ecc90323c900ef80fee 833 Gene3D G3DSA:3.40.50.11380 459 812 4.5E-158 T 14-10-2018 TSH58p_24710 1353cf0d53073ecc90323c900ef80fee 833 Pfam PF13432 Tetratricopeptide repeat 286 325 0.0069 T 14-10-2018 TSH58p_24710 1353cf0d53073ecc90323c900ef80fee 833 Pfam PF13432 Tetratricopeptide repeat 329 381 0.0043 T 14-10-2018 TSH58p_24710 1353cf0d53073ecc90323c900ef80fee 833 Pfam PF13432 Tetratricopeptide repeat 52 109 4.5E-6 T 14-10-2018 TSH58p_24710 1353cf0d53073ecc90323c900ef80fee 833 Gene3D G3DSA:1.25.40.10 241 281 1.5E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_24710 1353cf0d53073ecc90323c900ef80fee 833 Gene3D G3DSA:1.25.40.10 3 174 5.0E-35 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_24710 1353cf0d53073ecc90323c900ef80fee 833 Gene3D G3DSA:1.25.40.10 175 240 1.7E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_24710 1353cf0d53073ecc90323c900ef80fee 833 SUPERFAMILY SSF53756 471 821 1.02E-9 T 14-10-2018 TSH58p_24710 1353cf0d53073ecc90323c900ef80fee 833 Gene3D G3DSA:3.40.50.2000 626 805 4.5E-158 T 14-10-2018 TSH58p_24710 1353cf0d53073ecc90323c900ef80fee 833 SUPERFAMILY SSF48452 239 386 4.27E-20 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_24710 1353cf0d53073ecc90323c900ef80fee 833 SMART SM00028 179 212 210.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24710 1353cf0d53073ecc90323c900ef80fee 833 SMART SM00028 145 178 6.3E-5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24710 1353cf0d53073ecc90323c900ef80fee 833 SMART SM00028 349 382 150.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24710 1353cf0d53073ecc90323c900ef80fee 833 SMART SM00028 77 110 3.5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24710 1353cf0d53073ecc90323c900ef80fee 833 SMART SM00028 315 348 19.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24710 1353cf0d53073ecc90323c900ef80fee 833 SMART SM00028 247 280 0.18 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24710 1353cf0d53073ecc90323c900ef80fee 833 SMART SM00028 111 144 9.8E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24710 1353cf0d53073ecc90323c900ef80fee 833 SMART SM00028 281 314 160.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24710 1353cf0d53073ecc90323c900ef80fee 833 SMART SM00028 10 43 0.59 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24710 1353cf0d53073ecc90323c900ef80fee 833 Pfam PF13424 Tetratricopeptide repeat 113 174 5.2E-9 T 14-10-2018 TSH58p_24710 1353cf0d53073ecc90323c900ef80fee 833 Pfam PF13176 Tetratricopeptide repeat 12 44 0.0023 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_20890 aead1e5ac1f27ed871a03bc64f31fdcd 879 SUPERFAMILY SSF48452 10 179 1.04E-25 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_20890 aead1e5ac1f27ed871a03bc64f31fdcd 879 Pfam PF13432 Tetratricopeptide repeat 290 350 6.9E-8 T 14-10-2018 TSH58p_20890 aead1e5ac1f27ed871a03bc64f31fdcd 879 Pfam PF13432 Tetratricopeptide repeat 390 455 2.5E-6 T 14-10-2018 TSH58p_20890 aead1e5ac1f27ed871a03bc64f31fdcd 879 Pfam PF13432 Tetratricopeptide repeat 120 181 9.1E-4 T 14-10-2018 TSH58p_20890 aead1e5ac1f27ed871a03bc64f31fdcd 879 Pfam PF13432 Tetratricopeptide repeat 17 76 8.0E-7 T 14-10-2018 TSH58p_20890 aead1e5ac1f27ed871a03bc64f31fdcd 879 Pfam PF13432 Tetratricopeptide repeat 186 247 7.2E-5 T 14-10-2018 TSH58p_20890 aead1e5ac1f27ed871a03bc64f31fdcd 879 SUPERFAMILY SSF53756 509 840 1.43E-5 T 14-10-2018 TSH58p_20890 aead1e5ac1f27ed871a03bc64f31fdcd 879 SUPERFAMILY SSF48452 145 281 8.54E-16 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_20890 aead1e5ac1f27ed871a03bc64f31fdcd 879 Gene3D G3DSA:1.25.40.10 424 477 1.0E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_20890 aead1e5ac1f27ed871a03bc64f31fdcd 879 Pfam PF13844 Glycosyl transferase family 41 508 650 2.1E-15 T 14-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 TSH58p_20890 aead1e5ac1f27ed871a03bc64f31fdcd 879 Pfam PF13844 Glycosyl transferase family 41 680 862 3.9E-25 T 14-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 TSH58p_20890 aead1e5ac1f27ed871a03bc64f31fdcd 879 Gene3D G3DSA:1.25.40.10 284 423 1.1E-27 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_20890 aead1e5ac1f27ed871a03bc64f31fdcd 879 Gene3D G3DSA:1.25.40.10 1 124 1.7E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_20890 aead1e5ac1f27ed871a03bc64f31fdcd 879 Gene3D G3DSA:1.25.40.10 125 283 1.0E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_20890 aead1e5ac1f27ed871a03bc64f31fdcd 879 SUPERFAMILY SSF48452 283 458 7.3E-31 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_20890 aead1e5ac1f27ed871a03bc64f31fdcd 879 SMART SM00028 80 113 4.3 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_20890 aead1e5ac1f27ed871a03bc64f31fdcd 879 SMART SM00028 148 181 17.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_20890 aead1e5ac1f27ed871a03bc64f31fdcd 879 SMART SM00028 12 45 20.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_20890 aead1e5ac1f27ed871a03bc64f31fdcd 879 SMART SM00028 385 418 11.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_20890 aead1e5ac1f27ed871a03bc64f31fdcd 879 SMART SM00028 46 79 46.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_20890 aead1e5ac1f27ed871a03bc64f31fdcd 879 SMART SM00028 114 147 30.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_20890 aead1e5ac1f27ed871a03bc64f31fdcd 879 SMART SM00028 317 350 0.019 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_20890 aead1e5ac1f27ed871a03bc64f31fdcd 879 SMART SM00028 182 215 2.6 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_20890 aead1e5ac1f27ed871a03bc64f31fdcd 879 SMART SM00028 421 454 6.5E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_20890 aead1e5ac1f27ed871a03bc64f31fdcd 879 SMART SM00028 351 384 26.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_20890 aead1e5ac1f27ed871a03bc64f31fdcd 879 SMART SM00028 283 316 11.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_20890 aead1e5ac1f27ed871a03bc64f31fdcd 879 Gene3D G3DSA:3.40.50.2000 666 844 9.8E-112 T 14-10-2018 TSH58p_20890 aead1e5ac1f27ed871a03bc64f31fdcd 879 Gene3D G3DSA:3.40.50.11380 499 850 9.8E-112 T 14-10-2018 TSH58p_22470 8a34b2ad6da9b2b901701f0a9e3afc23 92 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 48 8.1E-22 T 14-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 TSH58p_22470 8a34b2ad6da9b2b901701f0a9e3afc23 92 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 85 21.061 T 14-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 TSH58p_22470 8a34b2ad6da9b2b901701f0a9e3afc23 92 Pfam PF02416 mttA/Hcf106 family 5 49 1.4E-14 T 14-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 TSH58p_04015 bbe122e713c82f1f37b42b7dfc7d7cc0 378 SUPERFAMILY SSF51419 19 237 4.11E-57 T 14-10-2018 IPR029066 PLP-binding barrel TSH58p_04015 bbe122e713c82f1f37b42b7dfc7d7cc0 378 Pfam PF00842 Alanine racemase, C-terminal domain 246 369 1.4E-35 T 14-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_04015 bbe122e713c82f1f37b42b7dfc7d7cc0 378 Pfam PF01168 Alanine racemase, N-terminal domain 19 233 1.7E-56 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_04015 bbe122e713c82f1f37b42b7dfc7d7cc0 378 SUPERFAMILY SSF50621 239 371 4.53E-41 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TSH58p_04015 bbe122e713c82f1f37b42b7dfc7d7cc0 378 PRINTS PR00992 Alanine racemase signature 73 91 2.8E-44 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_04015 bbe122e713c82f1f37b42b7dfc7d7cc0 378 PRINTS PR00992 Alanine racemase signature 206 233 2.8E-44 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_04015 bbe122e713c82f1f37b42b7dfc7d7cc0 378 PRINTS PR00992 Alanine racemase signature 135 147 2.8E-44 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_04015 bbe122e713c82f1f37b42b7dfc7d7cc0 378 PRINTS PR00992 Alanine racemase signature 37 53 2.8E-44 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_04015 bbe122e713c82f1f37b42b7dfc7d7cc0 378 PRINTS PR00992 Alanine racemase signature 352 365 2.8E-44 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_04015 bbe122e713c82f1f37b42b7dfc7d7cc0 378 PRINTS PR00992 Alanine racemase signature 169 180 2.8E-44 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_04015 bbe122e713c82f1f37b42b7dfc7d7cc0 378 PRINTS PR00992 Alanine racemase signature 298 315 2.8E-44 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_04015 bbe122e713c82f1f37b42b7dfc7d7cc0 378 PRINTS PR00992 Alanine racemase signature 277 292 2.8E-44 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_04015 bbe122e713c82f1f37b42b7dfc7d7cc0 378 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 42 52 - T 14-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_04015 bbe122e713c82f1f37b42b7dfc7d7cc0 378 Hamap MF_01201 Alanine racemase. 12 370 29.13 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_04015 bbe122e713c82f1f37b42b7dfc7d7cc0 378 Gene3D G3DSA:3.20.20.10 21 231 1.9E-114 T 14-10-2018 IPR029066 PLP-binding barrel TSH58p_04015 bbe122e713c82f1f37b42b7dfc7d7cc0 378 Gene3D G3DSA:2.40.37.10 20 369 1.9E-114 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TSH58p_04015 bbe122e713c82f1f37b42b7dfc7d7cc0 378 SMART SM01005 244 370 2.7E-53 T 14-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_04015 bbe122e713c82f1f37b42b7dfc7d7cc0 378 TIGRFAM TIGR00492 alr: alanine racemase 15 369 2.9E-74 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_05375 3e5bc89759a9681b97bc2781e9355a62 290 Gene3D G3DSA:3.40.50.1820 12 260 2.5E-37 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_05375 3e5bc89759a9681b97bc2781e9355a62 290 SUPERFAMILY SSF53474 11 262 1.58E-39 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_05375 3e5bc89759a9681b97bc2781e9355a62 290 Pfam PF12697 Alpha/beta hydrolase family 20 251 1.2E-21 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_20230 c7ccc48853da0779f514babc31c0838f 113 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 35 106 1.2E-22 T 14-10-2018 IPR001543 Surface presentation of antigen (SpoA) TSH58p_20230 c7ccc48853da0779f514babc31c0838f 113 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 33 108 3.4E-28 T 14-10-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 TSH58p_20230 c7ccc48853da0779f514babc31c0838f 113 SUPERFAMILY SSF101801 33 108 1.44E-20 T 14-10-2018 IPR036429 SpoA-like superfamily TSH58p_20230 c7ccc48853da0779f514babc31c0838f 113 PRINTS PR00956 Flagellar motor switch protein FliN signature 35 51 1.5E-23 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 TSH58p_20230 c7ccc48853da0779f514babc31c0838f 113 PRINTS PR00956 Flagellar motor switch protein FliN signature 68 81 1.5E-23 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 TSH58p_20230 c7ccc48853da0779f514babc31c0838f 113 PRINTS PR00956 Flagellar motor switch protein FliN signature 52 68 1.5E-23 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 TSH58p_20230 c7ccc48853da0779f514babc31c0838f 113 PRINTS PR00956 Flagellar motor switch protein FliN signature 81 96 1.5E-23 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 TSH58p_20230 c7ccc48853da0779f514babc31c0838f 113 Gene3D G3DSA:2.30.330.10 25 112 2.3E-28 T 14-10-2018 IPR036429 SpoA-like superfamily TSH58p_00790 f936867591dd8358e8af4e2c567c2e9f 664 Gene3D G3DSA:1.20.120.30 543 651 8.0E-7 T 14-10-2018 TSH58p_00790 f936867591dd8358e8af4e2c567c2e9f 664 Pfam PF07238 PilZ domain 455 526 7.0E-5 T 14-10-2018 IPR009875 PilZ domain GO:0035438 TSH58p_00790 f936867591dd8358e8af4e2c567c2e9f 664 Gene3D G3DSA:1.10.490.10 12 166 1.7E-38 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 TSH58p_00790 f936867591dd8358e8af4e2c567c2e9f 664 Gene3D G3DSA:1.10.287.950 167 454 3.5E-49 T 14-10-2018 TSH58p_00790 f936867591dd8358e8af4e2c567c2e9f 664 Pfam PF11563 Protoglobin 14 164 4.2E-29 T 14-10-2018 TSH58p_00790 f936867591dd8358e8af4e2c567c2e9f 664 SUPERFAMILY SSF58104 154 439 1.7E-53 T 14-10-2018 TSH58p_00790 f936867591dd8358e8af4e2c567c2e9f 664 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 256 415 1.4E-29 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_00790 f936867591dd8358e8af4e2c567c2e9f 664 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 366 395 5.3E-9 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_00790 f936867591dd8358e8af4e2c567c2e9f 664 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 219 248 5.3E-9 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_00790 f936867591dd8358e8af4e2c567c2e9f 664 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 318 347 5.3E-9 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_00790 f936867591dd8358e8af4e2c567c2e9f 664 Pfam PF13682 Chemoreceptor zinc-binding domain 553 618 2.2E-12 T 14-10-2018 IPR025991 Chemoreceptor zinc-binding domain TSH58p_00790 f936867591dd8358e8af4e2c567c2e9f 664 SMART SM00283 187 438 3.5E-33 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_00790 f936867591dd8358e8af4e2c567c2e9f 664 SUPERFAMILY SSF46458 14 158 1.44E-29 T 14-10-2018 IPR009050 Globin-like superfamily TSH58p_07855 75e235215ecd6ddc42c3ceb21532564f 368 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 22 98 6.8E-18 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_07855 75e235215ecd6ddc42c3ceb21532564f 368 Gene3D G3DSA:1.10.287.950 3 122 9.1E-23 T 14-10-2018 TSH58p_07855 75e235215ecd6ddc42c3ceb21532564f 368 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 54 83 1.8E-11 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_07855 75e235215ecd6ddc42c3ceb21532564f 368 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 25 52 1.8E-11 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_07855 75e235215ecd6ddc42c3ceb21532564f 368 SUPERFAMILY SSF58104 20 93 2.22E-23 T 14-10-2018 TSH58p_07855 75e235215ecd6ddc42c3ceb21532564f 368 Gene3D G3DSA:3.30.450.20 124 248 1.1E-6 T 14-10-2018 TSH58p_09800 374ae81dd85f434e81cfc0ac651474a6 78 Gene3D G3DSA:2.20.25.10 26 77 2.4E-24 T 14-10-2018 TSH58p_09800 374ae81dd85f434e81cfc0ac651474a6 78 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 19 72 28.056 T 14-10-2018 IPR038053 Uncharacterised protein family UPF0434 TSH58p_09800 374ae81dd85f434e81cfc0ac651474a6 78 SUPERFAMILY SSF158997 19 72 3.27E-21 T 14-10-2018 TSH58p_09800 374ae81dd85f434e81cfc0ac651474a6 78 Pfam PF03966 Trm112p-like protein 20 59 3.4E-10 T 14-10-2018 IPR005651 Trm112-like TSH58p_17320 6c0b7e25c5f684458532d03d5a9c0d84 323 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 107 190 7.3E-32 T 14-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TSH58p_17320 6c0b7e25c5f684458532d03d5a9c0d84 323 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 3 323 71.226 T 14-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TSH58p_17320 6c0b7e25c5f684458532d03d5a9c0d84 323 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 234 323 3.7E-38 T 14-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TSH58p_17320 6c0b7e25c5f684458532d03d5a9c0d84 323 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 4 323 4.0E-128 T 14-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TSH58p_17320 6c0b7e25c5f684458532d03d5a9c0d84 323 SUPERFAMILY SSF53901 3 323 4.83E-74 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_17320 6c0b7e25c5f684458532d03d5a9c0d84 323 Gene3D G3DSA:3.40.47.10 2 323 1.6E-129 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_03150 2fcbaf78eac18c7597f9df776c503a00 265 Pfam PF00455 DeoR C terminal sensor domain 76 232 2.2E-53 T 14-10-2018 IPR014036 DeoR C-terminal sensor domain TSH58p_03150 2fcbaf78eac18c7597f9df776c503a00 265 Pfam PF08220 DeoR-like helix-turn-helix domain 7 59 1.4E-14 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TSH58p_03150 2fcbaf78eac18c7597f9df776c503a00 265 SUPERFAMILY SSF46785 4 68 3.62E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_03150 2fcbaf78eac18c7597f9df776c503a00 265 Gene3D G3DSA:1.10.10.10 2 68 4.0E-5 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_03150 2fcbaf78eac18c7597f9df776c503a00 265 SUPERFAMILY SSF100950 76 234 1.1E-29 T 14-10-2018 IPR037171 NagB/RpiA transferase-like TSH58p_03150 2fcbaf78eac18c7597f9df776c503a00 265 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 25 39 1.9E-8 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TSH58p_03150 2fcbaf78eac18c7597f9df776c503a00 265 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 39 57 1.9E-8 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TSH58p_03150 2fcbaf78eac18c7597f9df776c503a00 265 SMART SM01134 73 234 4.1E-71 T 14-10-2018 TSH58p_03150 2fcbaf78eac18c7597f9df776c503a00 265 SMART SM00420 7 59 4.3E-14 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TSH58p_31795 33c51c465906a19f0d1dae90e6809c09 476 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 4 466 8.6E-206 T 14-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 TSH58p_31795 33c51c465906a19f0d1dae90e6809c09 476 Gene3D G3DSA:3.30.499.20 6 288 3.8E-92 T 14-10-2018 TSH58p_31795 33c51c465906a19f0d1dae90e6809c09 476 PRINTS PR00415 Aconitase family signature 121 134 1.1E-42 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_31795 33c51c465906a19f0d1dae90e6809c09 476 PRINTS PR00415 Aconitase family signature 197 210 1.1E-42 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_31795 33c51c465906a19f0d1dae90e6809c09 476 PRINTS PR00415 Aconitase family signature 288 302 1.1E-42 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_31795 33c51c465906a19f0d1dae90e6809c09 476 PRINTS PR00415 Aconitase family signature 211 224 1.1E-42 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_31795 33c51c465906a19f0d1dae90e6809c09 476 PRINTS PR00415 Aconitase family signature 345 356 1.1E-42 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_31795 33c51c465906a19f0d1dae90e6809c09 476 PRINTS PR00415 Aconitase family signature 135 150 1.1E-42 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_31795 33c51c465906a19f0d1dae90e6809c09 476 PRINTS PR00415 Aconitase family signature 401 414 1.1E-42 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_31795 33c51c465906a19f0d1dae90e6809c09 476 PRINTS PR00415 Aconitase family signature 110 118 1.1E-42 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_31795 33c51c465906a19f0d1dae90e6809c09 476 SUPERFAMILY SSF53732 4 469 2.49E-162 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 TSH58p_31795 33c51c465906a19f0d1dae90e6809c09 476 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 3 468 55.366 T 14-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 TSH58p_31795 33c51c465906a19f0d1dae90e6809c09 476 ProSitePatterns PS00450 Aconitase family signature 1. 341 357 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 TSH58p_31795 33c51c465906a19f0d1dae90e6809c09 476 Pfam PF00330 Aconitase family (aconitate hydratase) 9 459 3.6E-152 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_31795 33c51c465906a19f0d1dae90e6809c09 476 Gene3D G3DSA:3.30.499.10 329 474 1.2E-52 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 TSH58p_18670 519b550ef727a33a1d0d541cd3bbd3d5 488 SMART SM00345 37 96 4.0E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_18670 519b550ef727a33a1d0d541cd3bbd3d5 488 Gene3D G3DSA:3.90.1150.10 141 475 6.4E-67 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_18670 519b550ef727a33a1d0d541cd3bbd3d5 488 Pfam PF00392 Bacterial regulatory proteins, gntR family 36 96 5.6E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_18670 519b550ef727a33a1d0d541cd3bbd3d5 488 Pfam PF00155 Aminotransferase class I and II 126 472 8.0E-23 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSH58p_18670 519b550ef727a33a1d0d541cd3bbd3d5 488 SUPERFAMILY SSF53383 90 477 4.3E-74 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_18670 519b550ef727a33a1d0d541cd3bbd3d5 488 Gene3D G3DSA:3.40.640.10 159 375 6.4E-67 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_18670 519b550ef727a33a1d0d541cd3bbd3d5 488 SUPERFAMILY SSF46785 29 106 2.9E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_18670 519b550ef727a33a1d0d541cd3bbd3d5 488 Gene3D G3DSA:1.10.10.10 26 97 2.8E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_15575 bde80cd5647e3d65c2212924321d2642 563 Gene3D G3DSA:1.10.287.950 273 558 7.0E-53 T 14-10-2018 TSH58p_15575 bde80cd5647e3d65c2212924321d2642 563 SMART SM00304 214 267 2.9E-6 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_15575 bde80cd5647e3d65c2212924321d2642 563 Gene3D G3DSA:1.10.8.500 215 264 1.8E-14 T 14-10-2018 TSH58p_15575 bde80cd5647e3d65c2212924321d2642 563 SMART SM00283 303 557 1.6E-48 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_15575 bde80cd5647e3d65c2212924321d2642 563 Pfam PF12729 Four helix bundle sensory module for signal transduction 8 182 1.0E-8 T 14-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain TSH58p_15575 bde80cd5647e3d65c2212924321d2642 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 478 507 5.4E-24 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_15575 bde80cd5647e3d65c2212924321d2642 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 8 33 5.4E-24 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_15575 bde80cd5647e3d65c2212924321d2642 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 430 459 5.4E-24 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_15575 bde80cd5647e3d65c2212924321d2642 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 401 428 5.4E-24 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_15575 bde80cd5647e3d65c2212924321d2642 563 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 367 527 1.1E-29 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_15575 bde80cd5647e3d65c2212924321d2642 563 Pfam PF00672 HAMP domain 216 263 5.3E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_15575 bde80cd5647e3d65c2212924321d2642 563 SUPERFAMILY SSF58104 243 556 3.53E-61 T 14-10-2018 TSH58p_09500 40d26c8c79108f8fa6de7dcff134c1eb 203 Gene3D G3DSA:3.20.19.10 1 175 1.1E-76 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 TSH58p_09500 40d26c8c79108f8fa6de7dcff134c1eb 203 Pfam PF00694 Aconitase C-terminal domain 1 123 2.0E-38 T 14-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 TSH58p_09500 40d26c8c79108f8fa6de7dcff134c1eb 203 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 201 42.109 T 14-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 TSH58p_09500 40d26c8c79108f8fa6de7dcff134c1eb 203 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 184 3.3E-79 T 14-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 TSH58p_09500 40d26c8c79108f8fa6de7dcff134c1eb 203 SUPERFAMILY SSF52016 1 191 4.91E-59 T 14-10-2018 TSH58p_32580 c1c8e37c52c2c6d1b815d56fdebd2549 107 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 91 1.8E-13 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 TSH58p_32580 c1c8e37c52c2c6d1b815d56fdebd2549 107 PRINTS PR00355 Adrenodoxin signature 40 50 9.8E-10 T 14-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 TSH58p_32580 c1c8e37c52c2c6d1b815d56fdebd2549 107 PRINTS PR00355 Adrenodoxin signature 59 73 9.8E-10 T 14-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 TSH58p_32580 c1c8e37c52c2c6d1b815d56fdebd2549 107 PRINTS PR00355 Adrenodoxin signature 83 91 9.8E-10 T 14-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 TSH58p_32580 c1c8e37c52c2c6d1b815d56fdebd2549 107 Gene3D G3DSA:3.10.20.30 1 107 9.5E-37 T 14-10-2018 IPR012675 Beta-grasp domain superfamily TSH58p_32580 c1c8e37c52c2c6d1b815d56fdebd2549 107 SUPERFAMILY SSF54292 3 105 3.44E-34 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TSH58p_32580 c1c8e37c52c2c6d1b815d56fdebd2549 107 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 40 50 - T 14-10-2018 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 TSH58p_24850 af7edd24bbf88229a95301713aa6b368 825 Gene3D G3DSA:2.60.60.40 10 131 1.6E-5 T 14-10-2018 TSH58p_24850 af7edd24bbf88229a95301713aa6b368 825 Gene3D G3DSA:2.60.60.40 146 260 2.3E-7 T 14-10-2018 TSH58p_24850 af7edd24bbf88229a95301713aa6b368 825 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 322 641 9.6E-54 T 14-10-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 TSH58p_24850 af7edd24bbf88229a95301713aa6b368 825 Pfam PF16841 Ca-dependent carbohydrate-binding module xylan-binding 149 239 2.0E-27 T 14-10-2018 IPR031768 Carbohydrate binding module, xylan-binding domain MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSH58p_24850 af7edd24bbf88229a95301713aa6b368 825 Pfam PF16841 Ca-dependent carbohydrate-binding module xylan-binding 12 103 8.8E-30 T 14-10-2018 IPR031768 Carbohydrate binding module, xylan-binding domain MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSH58p_24850 af7edd24bbf88229a95301713aa6b368 825 Gene3D G3DSA:3.20.20.80 309 665 3.2E-109 T 14-10-2018 TSH58p_24850 af7edd24bbf88229a95301713aa6b368 825 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 465 474 - T 14-10-2018 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 TSH58p_24850 af7edd24bbf88229a95301713aa6b368 825 SMART SM00237 658 750 1.5E-11 T 14-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 TSH58p_24850 af7edd24bbf88229a95301713aa6b368 825 SUPERFAMILY SSF51445 311 666 3.22E-78 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_24850 af7edd24bbf88229a95301713aa6b368 825 SUPERFAMILY SSF141072 679 772 2.62E-27 T 14-10-2018 IPR038081 CalX-like domain superfamily TSH58p_24850 af7edd24bbf88229a95301713aa6b368 825 Pfam PF03160 Calx-beta domain 681 750 5.9E-19 T 14-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 TSH58p_24850 af7edd24bbf88229a95301713aa6b368 825 Gene3D G3DSA:2.60.40.2030 669 792 4.6E-28 T 14-10-2018 IPR038081 CalX-like domain superfamily TSH58p_29635 c6a771868ec9a6be2fb07c419c017ea3 814 PIRSF PIRSF001174 26 804 1.0E-284 T 14-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 TSH58p_29635 c6a771868ec9a6be2fb07c419c017ea3 814 Gene3D G3DSA:1.10.8.60 521 613 3.7E-27 T 14-10-2018 TSH58p_29635 c6a771868ec9a6be2fb07c419c017ea3 814 SUPERFAMILY SSF54211 624 799 2.81E-51 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSH58p_29635 c6a771868ec9a6be2fb07c419c017ea3 814 SMART SM00382 377 522 2.9E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_29635 c6a771868ec9a6be2fb07c419c017ea3 814 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 599 801 1.5E-83 T 14-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 TSH58p_29635 c6a771868ec9a6be2fb07c419c017ea3 814 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 381 518 1.2E-20 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSH58p_29635 c6a771868ec9a6be2fb07c419c017ea3 814 TIGRFAM TIGR00763 lon: endopeptidase La 40 799 2.3E-275 T 14-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 TSH58p_29635 c6a771868ec9a6be2fb07c419c017ea3 814 Gene3D G3DSA:2.30.130.40 34 146 2.4E-31 T 14-10-2018 TSH58p_29635 c6a771868ec9a6be2fb07c419c017ea3 814 SUPERFAMILY SSF52540 337 585 1.89E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_29635 c6a771868ec9a6be2fb07c419c017ea3 814 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 705 713 - T 14-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 TSH58p_29635 c6a771868ec9a6be2fb07c419c017ea3 814 Gene3D G3DSA:3.30.230.10 623 812 8.5E-78 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSH58p_29635 c6a771868ec9a6be2fb07c419c017ea3 814 SUPERFAMILY SSF88697 38 228 1.29E-42 T 14-10-2018 IPR015947 PUA-like superfamily TSH58p_29635 c6a771868ec9a6be2fb07c419c017ea3 814 Hamap MF_01973 Lon protease [lon]. 39 801 67.457 T 14-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 TSH58p_29635 c6a771868ec9a6be2fb07c419c017ea3 814 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 38 229 1.2E-39 T 14-10-2018 IPR003111 Lon, substrate-binding domain TSH58p_29635 c6a771868ec9a6be2fb07c419c017ea3 814 SMART SM00464 38 230 1.7E-50 T 14-10-2018 IPR003111 Lon, substrate-binding domain TSH58p_29635 c6a771868ec9a6be2fb07c419c017ea3 814 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 702 721 1.4E-52 T 14-10-2018 TSH58p_29635 c6a771868ec9a6be2fb07c419c017ea3 814 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 755 773 1.4E-52 T 14-10-2018 TSH58p_29635 c6a771868ec9a6be2fb07c419c017ea3 814 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 624 640 1.4E-52 T 14-10-2018 TSH58p_29635 c6a771868ec9a6be2fb07c419c017ea3 814 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 732 751 1.4E-52 T 14-10-2018 TSH58p_29635 c6a771868ec9a6be2fb07c419c017ea3 814 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 385 404 1.4E-52 T 14-10-2018 TSH58p_29635 c6a771868ec9a6be2fb07c419c017ea3 814 Gene3D G3DSA:3.40.50.300 343 520 6.3E-66 T 14-10-2018 TSH58p_29635 c6a771868ec9a6be2fb07c419c017ea3 814 Gene3D G3DSA:1.20.58.1480 149 273 3.8E-36 T 14-10-2018 TSH58p_09910 5a71fe5877a1f865b61a502b2a950693 296 Hamap MF_00188 Protease HtpX [htpX]. 4 284 28.886 T 14-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 TSH58p_09910 5a71fe5877a1f865b61a502b2a950693 296 Pfam PF01435 Peptidase family M48 73 284 1.1E-38 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 TSH58p_09910 5a71fe5877a1f865b61a502b2a950693 296 Gene3D G3DSA:3.30.2010.10 60 149 2.9E-31 T 14-10-2018 TSH58p_09705 d234368564d264553bf9a2def6271acf 477 SMART SM00487 21 223 6.1E-59 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSH58p_09705 d234368564d264553bf9a2def6271acf 477 Gene3D G3DSA:3.40.50.300 214 378 2.8E-51 T 14-10-2018 TSH58p_09705 d234368564d264553bf9a2def6271acf 477 Gene3D G3DSA:3.40.50.300 1 211 1.1E-73 T 14-10-2018 TSH58p_09705 d234368564d264553bf9a2def6271acf 477 SUPERFAMILY SSF52540 76 362 2.73E-76 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_09705 d234368564d264553bf9a2def6271acf 477 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 154 162 - T 14-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site TSH58p_09705 d234368564d264553bf9a2def6271acf 477 SMART SM00490 259 340 1.8E-34 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_09705 d234368564d264553bf9a2def6271acf 477 Pfam PF00271 Helicase conserved C-terminal domain 232 340 2.1E-28 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_09705 d234368564d264553bf9a2def6271acf 477 Pfam PF00270 DEAD/DEAH box helicase 26 194 7.8E-49 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TSH58p_05760 c1fee6bbbee4ff9b4e004722356ccd57 251 Pfam PF00696 Amino acid kinase family 17 226 1.2E-26 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TSH58p_05760 c1fee6bbbee4ff9b4e004722356ccd57 251 PIRSF PIRSF005650 12 251 8.3E-95 T 14-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 TSH58p_05760 c1fee6bbbee4ff9b4e004722356ccd57 251 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 17 247 5.9E-100 T 14-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 TSH58p_05760 c1fee6bbbee4ff9b4e004722356ccd57 251 Hamap MF_01220_B Uridylate kinase [pyrH]. 14 247 44.501 T 14-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 TSH58p_05760 c1fee6bbbee4ff9b4e004722356ccd57 251 Gene3D G3DSA:3.40.1160.10 13 251 4.3E-77 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSH58p_05760 c1fee6bbbee4ff9b4e004722356ccd57 251 SUPERFAMILY SSF53633 15 246 1.7E-70 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSH58p_31895 5dc1e5a435660f52ee2bbb717d9e7d42 1418 Gene3D G3DSA:3.40.50.2000 569 668 2.1E-5 T 14-10-2018 TSH58p_31895 5dc1e5a435660f52ee2bbb717d9e7d42 1418 Pfam PF13432 Tetratricopeptide repeat 1074 1116 9.6E-4 T 14-10-2018 TSH58p_31895 5dc1e5a435660f52ee2bbb717d9e7d42 1418 Pfam PF13432 Tetratricopeptide repeat 827 886 0.0043 T 14-10-2018 TSH58p_31895 5dc1e5a435660f52ee2bbb717d9e7d42 1418 Pfam PF13432 Tetratricopeptide repeat 935 991 2.1E-6 T 14-10-2018 TSH58p_31895 5dc1e5a435660f52ee2bbb717d9e7d42 1418 Pfam PF13432 Tetratricopeptide repeat 118 182 1.1E-4 T 14-10-2018 TSH58p_31895 5dc1e5a435660f52ee2bbb717d9e7d42 1418 Pfam PF13181 Tetratricopeptide repeat 994 1024 0.064 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_31895 5dc1e5a435660f52ee2bbb717d9e7d42 1418 SUPERFAMILY SSF53756 435 680 8.0E-22 T 14-10-2018 TSH58p_31895 5dc1e5a435660f52ee2bbb717d9e7d42 1418 SUPERFAMILY SSF48452 885 1123 2.77E-32 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_31895 5dc1e5a435660f52ee2bbb717d9e7d42 1418 SMART SM00028 957 990 0.36 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_31895 5dc1e5a435660f52ee2bbb717d9e7d42 1418 SMART SM00028 1025 1062 87.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_31895 5dc1e5a435660f52ee2bbb717d9e7d42 1418 SMART SM00028 923 956 3.2 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_31895 5dc1e5a435660f52ee2bbb717d9e7d42 1418 SMART SM00028 991 1024 6.7E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_31895 5dc1e5a435660f52ee2bbb717d9e7d42 1418 SMART SM00028 855 888 30.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_31895 5dc1e5a435660f52ee2bbb717d9e7d42 1418 SMART SM00028 148 181 0.015 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_31895 5dc1e5a435660f52ee2bbb717d9e7d42 1418 SMART SM00028 250 283 310.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_31895 5dc1e5a435660f52ee2bbb717d9e7d42 1418 SMART SM00028 787 820 11.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_31895 5dc1e5a435660f52ee2bbb717d9e7d42 1418 SMART SM00028 114 147 6.1 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_31895 5dc1e5a435660f52ee2bbb717d9e7d42 1418 SMART SM00028 889 922 38.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_31895 5dc1e5a435660f52ee2bbb717d9e7d42 1418 SMART SM00028 284 317 260.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_31895 5dc1e5a435660f52ee2bbb717d9e7d42 1418 SMART SM00028 1063 1096 120.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_31895 5dc1e5a435660f52ee2bbb717d9e7d42 1418 SUPERFAMILY SSF48452 164 410 1.24E-26 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_31895 5dc1e5a435660f52ee2bbb717d9e7d42 1418 SUPERFAMILY SSF53756 1147 1392 6.91E-21 T 14-10-2018 TSH58p_31895 5dc1e5a435660f52ee2bbb717d9e7d42 1418 Gene3D G3DSA:1.25.40.10 899 1128 1.6E-49 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_31895 5dc1e5a435660f52ee2bbb717d9e7d42 1418 Gene3D G3DSA:1.25.40.10 91 415 1.4E-46 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_31895 5dc1e5a435660f52ee2bbb717d9e7d42 1418 SUPERFAMILY SSF48452 97 196 1.21E-13 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_31895 5dc1e5a435660f52ee2bbb717d9e7d42 1418 Gene3D G3DSA:1.25.40.10 827 898 3.9E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_31895 5dc1e5a435660f52ee2bbb717d9e7d42 1418 SUPERFAMILY SSF48452 341 955 4.55E-30 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_31895 5dc1e5a435660f52ee2bbb717d9e7d42 1418 Gene3D G3DSA:1.25.40.10 721 826 3.2E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_03285 330b82ab75b4741ff4e92b8f890c33e9 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 254 5.6E-60 T 14-10-2018 TSH58p_03285 330b82ab75b4741ff4e92b8f890c33e9 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 6.6E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03285 330b82ab75b4741ff4e92b8f890c33e9 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 6.6E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03285 330b82ab75b4741ff4e92b8f890c33e9 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 6.6E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03285 330b82ab75b4741ff4e92b8f890c33e9 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 6.6E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03285 330b82ab75b4741ff4e92b8f890c33e9 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 6.6E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03285 330b82ab75b4741ff4e92b8f890c33e9 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 6.6E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03285 330b82ab75b4741ff4e92b8f890c33e9 261 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 188 0.0078 T 14-10-2018 TSH58p_03285 330b82ab75b4741ff4e92b8f890c33e9 261 Gene3D G3DSA:3.40.50.720 6 259 8.3E-82 T 14-10-2018 TSH58p_03285 330b82ab75b4741ff4e92b8f890c33e9 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 8.3E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03285 330b82ab75b4741ff4e92b8f890c33e9 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 8.3E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03285 330b82ab75b4741ff4e92b8f890c33e9 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 8.3E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03285 330b82ab75b4741ff4e92b8f890c33e9 261 SUPERFAMILY SSF51735 4 255 1.72E-76 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_30200 bfce1d5d7ff4ec29414f2cf9e4f008df 262 Pfam PF00005 ABC transporter 28 172 3.2E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_30200 bfce1d5d7ff4ec29414f2cf9e4f008df 262 SMART SM00382 33 221 4.6E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_30200 bfce1d5d7ff4ec29414f2cf9e4f008df 262 Gene3D G3DSA:3.40.50.300 2 260 8.0E-65 T 14-10-2018 TSH58p_30200 bfce1d5d7ff4ec29414f2cf9e4f008df 262 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_30200 bfce1d5d7ff4ec29414f2cf9e4f008df 262 SUPERFAMILY SSF52540 7 235 1.13E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_11535 f55e60fcbca1109bacc405b3bef79559 258 Gene3D G3DSA:1.10.12.10 201 257 1.6E-26 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal TSH58p_11535 f55e60fcbca1109bacc405b3bef79559 258 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 99 119 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 TSH58p_11535 f55e60fcbca1109bacc405b3bef79559 258 Gene3D G3DSA:3.90.226.10 2 199 2.1E-78 T 14-10-2018 TSH58p_11535 f55e60fcbca1109bacc405b3bef79559 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 257 7.7E-87 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TSH58p_11535 f55e60fcbca1109bacc405b3bef79559 258 SUPERFAMILY SSF52096 1 258 2.64E-92 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_02085 b7c031460d8639a89d4d01dad8028b5a 196 SUPERFAMILY SSF64288 49 183 7.59E-11 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TSH58p_02085 b7c031460d8639a89d4d01dad8028b5a 196 Gene3D G3DSA:3.40.1410.10 47 189 8.8E-10 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TSH58p_26965 a02fed31795c610e77a2978b65ecb4b1 170 Gene3D G3DSA:3.40.630.30 1 141 2.9E-23 T 14-10-2018 TSH58p_26965 a02fed31795c610e77a2978b65ecb4b1 170 SUPERFAMILY SSF55729 1 136 6.86E-27 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_26965 a02fed31795c610e77a2978b65ecb4b1 170 Pfam PF00583 Acetyltransferase (GNAT) family 27 134 2.4E-15 T 14-10-2018 IPR000182 GNAT domain TSH58p_22045 67f8e7fe00175930131e0494f31d95ac 942 Gene3D G3DSA:3.40.50.740 298 767 7.8E-167 T 14-10-2018 TSH58p_22045 67f8e7fe00175930131e0494f31d95ac 942 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 17 93 6.5E-25 T 14-10-2018 TSH58p_22045 67f8e7fe00175930131e0494f31d95ac 942 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 209 220 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_22045 67f8e7fe00175930131e0494f31d95ac 942 Pfam PF00384 Molybdopterin oxidoreductase 293 724 4.5E-71 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_22045 67f8e7fe00175930131e0494f31d95ac 942 SUPERFAMILY SSF50692 792 920 6.33E-37 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TSH58p_22045 67f8e7fe00175930131e0494f31d95ac 942 SUPERFAMILY SSF53706 237 759 6.54E-184 T 14-10-2018 TSH58p_22045 67f8e7fe00175930131e0494f31d95ac 942 Gene3D G3DSA:3.10.20.740 18 139 5.4E-39 T 14-10-2018 TSH58p_22045 67f8e7fe00175930131e0494f31d95ac 942 SMART SM00926 236 290 1.1E-13 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_22045 67f8e7fe00175930131e0494f31d95ac 942 Gene3D G3DSA:3.40.228.10 373 580 7.8E-167 T 14-10-2018 TSH58p_22045 67f8e7fe00175930131e0494f31d95ac 942 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 100 139 3.6E-17 T 14-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_22045 67f8e7fe00175930131e0494f31d95ac 942 SUPERFAMILY SSF54292 18 91 1.13E-19 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TSH58p_22045 67f8e7fe00175930131e0494f31d95ac 942 Gene3D G3DSA:2.20.25.90 237 289 6.0E-15 T 14-10-2018 TSH58p_22045 67f8e7fe00175930131e0494f31d95ac 942 Gene3D G3DSA:3.30.70.20 145 227 8.2E-24 T 14-10-2018 TSH58p_22045 67f8e7fe00175930131e0494f31d95ac 942 SUPERFAMILY SSF54862 93 232 1.13E-38 T 14-10-2018 TSH58p_22045 67f8e7fe00175930131e0494f31d95ac 942 Pfam PF00037 4Fe-4S binding domain 206 223 1.7E-5 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_22045 67f8e7fe00175930131e0494f31d95ac 942 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 237 288 4.4E-14 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_22045 67f8e7fe00175930131e0494f31d95ac 942 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 241 920 1.1E-272 T 14-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 TSH58p_22045 67f8e7fe00175930131e0494f31d95ac 942 Pfam PF01568 Molydopterin dinucleotide binding domain 812 916 2.7E-25 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TSH58p_22045 67f8e7fe00175930131e0494f31d95ac 942 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 850 877 - T 14-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 TSH58p_22045 67f8e7fe00175930131e0494f31d95ac 942 SMART SM00929 100 140 3.1E-19 T 14-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_22045 67f8e7fe00175930131e0494f31d95ac 942 PIRSF PIRSF036643 14 939 0.0 T 14-10-2018 TSH58p_22045 67f8e7fe00175930131e0494f31d95ac 942 Gene3D G3DSA:2.40.40.20 810 922 4.1E-33 T 14-10-2018 TSH58p_31755 f478586e2d8cc9980be17acc6420ca9b 319 Gene3D G3DSA:1.10.10.60 209 316 7.6E-33 T 14-10-2018 TSH58p_31755 f478586e2d8cc9980be17acc6420ca9b 319 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 281 296 6.6E-6 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TSH58p_31755 f478586e2d8cc9980be17acc6420ca9b 319 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 296 312 6.6E-6 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TSH58p_31755 f478586e2d8cc9980be17acc6420ca9b 319 SUPERFAMILY SSF46689 265 314 3.49E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_31755 f478586e2d8cc9980be17acc6420ca9b 319 SMART SM00342 229 312 2.2E-29 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TSH58p_31755 f478586e2d8cc9980be17acc6420ca9b 319 Pfam PF12833 Helix-turn-helix domain 235 313 8.1E-26 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TSH58p_31755 f478586e2d8cc9980be17acc6420ca9b 319 SUPERFAMILY SSF46689 212 263 5.2E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_31755 f478586e2d8cc9980be17acc6420ca9b 319 Gene3D G3DSA:3.40.50.880 1 199 1.7E-48 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_31755 f478586e2d8cc9980be17acc6420ca9b 319 Pfam PF01965 DJ-1/PfpI family 9 172 4.5E-13 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 TSH58p_31755 f478586e2d8cc9980be17acc6420ca9b 319 SUPERFAMILY SSF52317 2 191 3.21E-39 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 Pfam PF08448 PAS fold 371 483 3.3E-16 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 Pfam PF08448 PAS fold 504 607 1.1E-11 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 SUPERFAMILY SSF55785 354 480 5.76E-17 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 Gene3D G3DSA:3.40.50.2300 860 989 7.6E-21 T 14-10-2018 TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 PRINTS PR00344 Bacterial sensor protein C-terminal signature 827 840 4.8E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 PRINTS PR00344 Bacterial sensor protein C-terminal signature 803 821 4.8E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 PRINTS PR00344 Bacterial sensor protein C-terminal signature 789 799 4.8E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 PRINTS PR00344 Bacterial sensor protein C-terminal signature 771 785 4.8E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 Gene3D G3DSA:1.20.1480.50 267 362 4.6E-8 T 14-10-2018 TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 Gene3D G3DSA:3.30.565.10 691 845 2.3E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 Pfam PF02743 Cache domain 51 210 1.3E-12 T 14-10-2018 IPR033479 Double Cache domain 1 TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 SUPERFAMILY SSF158472 306 354 1.83E-7 T 14-10-2018 TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 SMART SM00388 625 690 1.3E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 SMART SM00448 870 984 9.5E-16 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 Gene3D G3DSA:3.30.450.20 371 492 4.6E-23 T 14-10-2018 TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 734 840 3.1E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 363 489 3.6E-11 T 14-10-2018 IPR000014 PAS domain TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 494 612 3.4E-9 T 14-10-2018 IPR000014 PAS domain TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 SMART SM00387 734 843 7.9E-28 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 Pfam PF00512 His Kinase A (phospho-acceptor) domain 626 690 1.6E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 Gene3D G3DSA:3.30.450.20 493 615 3.5E-19 T 14-10-2018 TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 SMART SM00091 365 431 5.8E-9 T 14-10-2018 IPR000014 PAS domain TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 SUPERFAMILY SSF55785 478 597 1.68E-15 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 Pfam PF00072 Response regulator receiver domain 872 984 1.3E-11 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 SUPERFAMILY SSF55874 680 845 1.7E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 SUPERFAMILY SSF52172 872 987 4.13E-21 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 SUPERFAMILY SSF47384 611 691 3.34E-13 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 SUPERFAMILY SSF103190 47 181 2.9E-5 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 Gene3D G3DSA:3.30.450.20 26 178 8.4E-23 T 14-10-2018 TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 Gene3D G3DSA:1.10.287.130 616 690 1.4E-12 T 14-10-2018 TSH58p_10075 05b098b1b4a643ee40a126a01c6744a2 990 SMART SM00304 305 358 4.0E-6 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_12415 58c13927dcd4fd5d6442e7667bedc011 225 SUPERFAMILY SSF103088 104 221 7.19E-29 T 14-10-2018 IPR036737 OmpA-like domain superfamily TSH58p_12415 58c13927dcd4fd5d6442e7667bedc011 225 Pfam PF00691 OmpA family 121 215 4.0E-21 T 14-10-2018 IPR006665 OmpA-like domain TSH58p_12415 58c13927dcd4fd5d6442e7667bedc011 225 PRINTS PR01021 OMPA domain signature 121 143 2.9E-16 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 TSH58p_12415 58c13927dcd4fd5d6442e7667bedc011 225 PRINTS PR01021 OMPA domain signature 153 168 2.9E-16 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 TSH58p_12415 58c13927dcd4fd5d6442e7667bedc011 225 PRINTS PR01021 OMPA domain signature 168 184 2.9E-16 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 TSH58p_12415 58c13927dcd4fd5d6442e7667bedc011 225 Gene3D G3DSA:3.30.1330.60 98 224 1.3E-30 T 14-10-2018 IPR036737 OmpA-like domain superfamily TSH58p_12415 58c13927dcd4fd5d6442e7667bedc011 225 ProSitePatterns PS01068 OmpA-like domain. 155 200 - T 14-10-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 TSH58p_18205 0e0fda13b5862146ccea2f2fdd2df2d6 375 Gene3D G3DSA:3.40.640.10 2 249 6.6E-75 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_18205 0e0fda13b5862146ccea2f2fdd2df2d6 375 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 22 368 3.9E-110 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase TSH58p_18205 0e0fda13b5862146ccea2f2fdd2df2d6 375 PIRSF PIRSF000390 2 375 3.3E-92 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase TSH58p_18205 0e0fda13b5862146ccea2f2fdd2df2d6 375 SUPERFAMILY SSF53383 19 372 3.54E-100 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_18205 0e0fda13b5862146ccea2f2fdd2df2d6 375 Gene3D G3DSA:3.90.1150.10 253 372 2.5E-38 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_10040 4f83aa34654511f7d07217c0bca3c323 527 SUPERFAMILY SSF56024 15 253 4.29E-29 T 14-10-2018 TSH58p_10040 4f83aa34654511f7d07217c0bca3c323 527 Pfam PF00614 Phospholipase D Active site motif 137 161 1.4E-5 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 TSH58p_10040 4f83aa34654511f7d07217c0bca3c323 527 Gene3D G3DSA:3.30.870.10 20 221 1.2E-23 T 14-10-2018 TSH58p_10040 4f83aa34654511f7d07217c0bca3c323 527 Gene3D G3DSA:3.30.870.10 258 416 8.5E-19 T 14-10-2018 TSH58p_10040 4f83aa34654511f7d07217c0bca3c323 527 Pfam PF13091 PLD-like domain 270 394 7.8E-11 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 TSH58p_10040 4f83aa34654511f7d07217c0bca3c323 527 SUPERFAMILY SSF56024 265 421 2.62E-24 T 14-10-2018 TSH58p_10040 4f83aa34654511f7d07217c0bca3c323 527 SMART SM00155 354 381 3.7E-6 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 TSH58p_10040 4f83aa34654511f7d07217c0bca3c323 527 SMART SM00155 134 161 0.0027 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 TSH58p_21980 8ed7bd7f50eed1a4166cf0f8c203c190 138 SMART SM00905 26 132 0.0035 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TSH58p_21980 8ed7bd7f50eed1a4166cf0f8c203c190 138 Pfam PF02152 Dihydroneopterin aldolase 45 131 3.6E-5 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TSH58p_21980 8ed7bd7f50eed1a4166cf0f8c203c190 138 SUPERFAMILY SSF55620 43 134 2.78E-9 T 14-10-2018 TSH58p_21980 8ed7bd7f50eed1a4166cf0f8c203c190 138 Gene3D G3DSA:3.30.1130.10 15 138 1.9E-14 T 14-10-2018 TSH58p_19030 96d801fe4132f6fcc8654486a821a706 241 SUPERFAMILY SSF46689 38 115 2.29E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_19030 96d801fe4132f6fcc8654486a821a706 241 SUPERFAMILY SSF48498 121 238 9.64E-10 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TSH58p_19030 96d801fe4132f6fcc8654486a821a706 241 Pfam PF00440 Bacterial regulatory proteins, tetR family 48 94 1.2E-15 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_19030 96d801fe4132f6fcc8654486a821a706 241 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 185 237 2.8E-14 T 14-10-2018 IPR039536 Transcriptional regulator TetR, C-terminal, Proteobacteria type TSH58p_19030 96d801fe4132f6fcc8654486a821a706 241 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 69 92 5.8E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_19030 96d801fe4132f6fcc8654486a821a706 241 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 61 5.8E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_19030 96d801fe4132f6fcc8654486a821a706 241 Gene3D G3DSA:1.10.357.10 37 241 1.4E-56 T 14-10-2018 TSH58p_19040 41a8c61bff0486c024a6eebdfb6c8292 921 SMART SM00387 670 781 1.3E-27 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_19040 41a8c61bff0486c024a6eebdfb6c8292 921 Pfam PF00512 His Kinase A (phospho-acceptor) domain 560 625 7.0E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_19040 41a8c61bff0486c024a6eebdfb6c8292 921 Pfam PF00072 Response regulator receiver domain 802 913 5.9E-10 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_19040 41a8c61bff0486c024a6eebdfb6c8292 921 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 433 553 7.3E-13 T 14-10-2018 IPR000014 PAS domain TSH58p_19040 41a8c61bff0486c024a6eebdfb6c8292 921 SUPERFAMILY SSF55785 422 544 1.71E-24 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_19040 41a8c61bff0486c024a6eebdfb6c8292 921 PRINTS PR00344 Bacterial sensor protein C-terminal signature 765 778 3.2E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_19040 41a8c61bff0486c024a6eebdfb6c8292 921 PRINTS PR00344 Bacterial sensor protein C-terminal signature 706 720 3.2E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_19040 41a8c61bff0486c024a6eebdfb6c8292 921 PRINTS PR00344 Bacterial sensor protein C-terminal signature 741 759 3.2E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_19040 41a8c61bff0486c024a6eebdfb6c8292 921 PRINTS PR00344 Bacterial sensor protein C-terminal signature 724 734 3.2E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_19040 41a8c61bff0486c024a6eebdfb6c8292 921 SUPERFAMILY SSF47384 548 625 2.55E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_19040 41a8c61bff0486c024a6eebdfb6c8292 921 SMART SM00091 437 500 0.053 T 14-10-2018 IPR000014 PAS domain TSH58p_19040 41a8c61bff0486c024a6eebdfb6c8292 921 SMART SM00091 309 374 16.0 T 14-10-2018 IPR000014 PAS domain TSH58p_19040 41a8c61bff0486c024a6eebdfb6c8292 921 Gene3D G3DSA:1.10.287.130 544 623 3.4E-16 T 14-10-2018 TSH58p_19040 41a8c61bff0486c024a6eebdfb6c8292 921 Gene3D G3DSA:3.30.450.20 297 432 7.3E-19 T 14-10-2018 TSH58p_19040 41a8c61bff0486c024a6eebdfb6c8292 921 SUPERFAMILY SSF52172 802 917 1.02E-17 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_19040 41a8c61bff0486c024a6eebdfb6c8292 921 Pfam PF08447 PAS fold 461 541 1.1E-9 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 TSH58p_19040 41a8c61bff0486c024a6eebdfb6c8292 921 Pfam PF08448 PAS fold 315 426 1.2E-6 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_19040 41a8c61bff0486c024a6eebdfb6c8292 921 Gene3D G3DSA:3.40.50.2300 800 920 4.0E-18 T 14-10-2018 TSH58p_19040 41a8c61bff0486c024a6eebdfb6c8292 921 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 671 780 6.3E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_19040 41a8c61bff0486c024a6eebdfb6c8292 921 Gene3D G3DSA:3.30.450.20 433 543 1.9E-24 T 14-10-2018 TSH58p_19040 41a8c61bff0486c024a6eebdfb6c8292 921 Gene3D G3DSA:3.30.565.10 631 784 2.2E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_19040 41a8c61bff0486c024a6eebdfb6c8292 921 SMART SM00448 799 913 6.7E-11 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_19040 41a8c61bff0486c024a6eebdfb6c8292 921 SUPERFAMILY SSF55785 328 434 3.32E-9 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_19040 41a8c61bff0486c024a6eebdfb6c8292 921 SMART SM00086 384 425 6.5 T 14-10-2018 IPR001610 PAC motif TSH58p_19040 41a8c61bff0486c024a6eebdfb6c8292 921 SMART SM00086 506 547 0.0015 T 14-10-2018 IPR001610 PAC motif TSH58p_19040 41a8c61bff0486c024a6eebdfb6c8292 921 Gene3D G3DSA:3.30.450.20 24 157 7.9E-11 T 14-10-2018 TSH58p_19040 41a8c61bff0486c024a6eebdfb6c8292 921 SUPERFAMILY SSF55874 614 779 1.26E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_19040 41a8c61bff0486c024a6eebdfb6c8292 921 SMART SM00388 560 625 7.0E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_26685 02b0f5e34f6a6fb2d60ef1b1f436c11f 387 SUPERFAMILY SSF53850 34 376 3.1E-27 T 14-10-2018 TSH58p_26685 02b0f5e34f6a6fb2d60ef1b1f436c11f 387 Gene3D G3DSA:3.40.190.10 58 334 4.9E-23 T 14-10-2018 TSH58p_26685 02b0f5e34f6a6fb2d60ef1b1f436c11f 387 Gene3D G3DSA:3.40.190.10 120 373 4.9E-23 T 14-10-2018 TSH58p_26685 02b0f5e34f6a6fb2d60ef1b1f436c11f 387 Pfam PF01547 Bacterial extracellular solute-binding protein 59 171 1.7E-5 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSH58p_30420 94121c7c767820818d4317f2e6c52c2a 474 Pfam PF04324 BFD-like [2Fe-2S] binding domain 390 438 1.0E-10 T 14-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain TSH58p_30420 94121c7c767820818d4317f2e6c52c2a 474 Gene3D G3DSA:3.50.50.60 122 273 8.6E-42 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_30420 94121c7c767820818d4317f2e6c52c2a 474 PIRSF PIRSF037495 1 474 3.4E-112 T 14-10-2018 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 TSH58p_30420 94121c7c767820818d4317f2e6c52c2a 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 8.2E-19 T 14-10-2018 TSH58p_30420 94121c7c767820818d4317f2e6c52c2a 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 8.2E-19 T 14-10-2018 TSH58p_30420 94121c7c767820818d4317f2e6c52c2a 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 297 319 8.2E-19 T 14-10-2018 TSH58p_30420 94121c7c767820818d4317f2e6c52c2a 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 110 128 8.2E-19 T 14-10-2018 TSH58p_30420 94121c7c767820818d4317f2e6c52c2a 474 Gene3D G3DSA:1.10.10.1100 380 447 8.8E-18 T 14-10-2018 TSH58p_30420 94121c7c767820818d4317f2e6c52c2a 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 154 179 3.8E-9 T 14-10-2018 TSH58p_30420 94121c7c767820818d4317f2e6c52c2a 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 3.8E-9 T 14-10-2018 TSH58p_30420 94121c7c767820818d4317f2e6c52c2a 474 SUPERFAMILY SSF51905 3 340 5.74E-37 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_30420 94121c7c767820818d4317f2e6c52c2a 474 Gene3D G3DSA:3.50.50.60 6 331 8.6E-42 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_30420 94121c7c767820818d4317f2e6c52c2a 474 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 182 1.3E-17 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSH58p_10125 5ad77dcdecc8809afb9b82bf5eeb3c27 210 Gene3D G3DSA:3.30.1130.10 72 205 3.3E-57 T 14-10-2018 TSH58p_10125 5ad77dcdecc8809afb9b82bf5eeb3c27 210 SUPERFAMILY SSF55620 13 203 6.37E-78 T 14-10-2018 TSH58p_10125 5ad77dcdecc8809afb9b82bf5eeb3c27 210 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 130 140 - T 14-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 TSH58p_10125 5ad77dcdecc8809afb9b82bf5eeb3c27 210 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 25 202 3.5E-68 T 14-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 TSH58p_10125 5ad77dcdecc8809afb9b82bf5eeb3c27 210 Pfam PF01227 GTP cyclohydrolase I 25 202 5.1E-76 T 14-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 TSH58p_10125 5ad77dcdecc8809afb9b82bf5eeb3c27 210 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 20 203 39.501 T 14-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 TSH58p_10125 5ad77dcdecc8809afb9b82bf5eeb3c27 210 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 82 98 - T 14-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 TSH58p_10125 5ad77dcdecc8809afb9b82bf5eeb3c27 210 Gene3D G3DSA:1.10.286.10 7 68 3.0E-18 T 14-10-2018 TSH58p_10850 16106937c68735998e2d84494552e22a 424 Pfam PF00534 Glycosyl transferases group 1 223 383 3.6E-30 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 TSH58p_10850 16106937c68735998e2d84494552e22a 424 Gene3D G3DSA:3.40.50.2000 202 390 1.2E-51 T 14-10-2018 TSH58p_10850 16106937c68735998e2d84494552e22a 424 SUPERFAMILY SSF53756 15 403 4.08E-60 T 14-10-2018 TSH58p_10850 16106937c68735998e2d84494552e22a 424 Gene3D G3DSA:3.40.50.2000 110 201 1.2E-51 T 14-10-2018 TSH58p_19550 7e284d99eea63dcb037bcd5940504419 848 Gene3D G3DSA:1.10.274.10 302 424 8.3E-60 T 14-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 TSH58p_19550 7e284d99eea63dcb037bcd5940504419 848 Gene3D G3DSA:3.30.1340.10 171 254 3.7E-18 T 14-10-2018 IPR035895 HPr-like superfamily TSH58p_19550 7e284d99eea63dcb037bcd5940504419 848 Pfam PF05524 PEP-utilising enzyme, N-terminal 285 403 1.2E-19 T 14-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 TSH58p_19550 7e284d99eea63dcb037bcd5940504419 848 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 530 818 1.2E-104 T 14-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 TSH58p_19550 7e284d99eea63dcb037bcd5940504419 848 Gene3D G3DSA:3.40.930.10 14 154 2.1E-31 T 14-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 TSH58p_19550 7e284d99eea63dcb037bcd5940504419 848 Pfam PF00391 PEP-utilising enzyme, mobile domain 433 504 3.5E-20 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TSH58p_19550 7e284d99eea63dcb037bcd5940504419 848 Gene3D G3DSA:3.20.20.60 513 847 1.6E-111 T 14-10-2018 TSH58p_19550 7e284d99eea63dcb037bcd5940504419 848 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 181 188 - T 14-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site TSH58p_19550 7e284d99eea63dcb037bcd5940504419 848 SUPERFAMILY SSF52009 403 522 3.92E-27 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 TSH58p_19550 7e284d99eea63dcb037bcd5940504419 848 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 60 76 - T 14-10-2018 IPR002178 PTS EIIA type-2 domain TSH58p_19550 7e284d99eea63dcb037bcd5940504419 848 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 726 744 - T 14-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 TSH58p_19550 7e284d99eea63dcb037bcd5940504419 848 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 16 152 8.3E-29 T 14-10-2018 IPR002178 PTS EIIA type-2 domain TSH58p_19550 7e284d99eea63dcb037bcd5940504419 848 SUPERFAMILY SSF55804 15 152 1.1E-34 T 14-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 TSH58p_19550 7e284d99eea63dcb037bcd5940504419 848 SUPERFAMILY SSF51621 530 821 4.45E-98 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSH58p_19550 7e284d99eea63dcb037bcd5940504419 848 PRINTS PR00107 Phosphocarrier protein signature 221 238 1.4E-9 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like TSH58p_19550 7e284d99eea63dcb037bcd5940504419 848 PRINTS PR00107 Phosphocarrier protein signature 181 197 1.4E-9 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like TSH58p_19550 7e284d99eea63dcb037bcd5940504419 848 PRINTS PR00107 Phosphocarrier protein signature 206 221 1.4E-9 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like TSH58p_19550 7e284d99eea63dcb037bcd5940504419 848 Pfam PF00381 PTS HPr component phosphorylation site 174 249 2.5E-18 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like TSH58p_19550 7e284d99eea63dcb037bcd5940504419 848 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 175 249 1.2E-14 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like TSH58p_19550 7e284d99eea63dcb037bcd5940504419 848 Gene3D G3DSA:3.50.30.10 285 512 8.3E-60 T 14-10-2018 TSH58p_19550 7e284d99eea63dcb037bcd5940504419 848 SUPERFAMILY SSF47831 319 418 2.35E-22 T 14-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 TSH58p_19550 7e284d99eea63dcb037bcd5940504419 848 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 463 474 - T 14-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 TSH58p_19550 7e284d99eea63dcb037bcd5940504419 848 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 779 791 1.4E-20 T 14-10-2018 TSH58p_19550 7e284d99eea63dcb037bcd5940504419 848 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 572 591 1.4E-20 T 14-10-2018 TSH58p_19550 7e284d99eea63dcb037bcd5940504419 848 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 726 741 1.4E-20 T 14-10-2018 TSH58p_19550 7e284d99eea63dcb037bcd5940504419 848 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 743 758 1.4E-20 T 14-10-2018 TSH58p_19550 7e284d99eea63dcb037bcd5940504419 848 SUPERFAMILY SSF55594 172 250 3.14E-18 T 14-10-2018 IPR035895 HPr-like superfamily TSH58p_19550 7e284d99eea63dcb037bcd5940504419 848 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 285 843 3.6E-136 T 14-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 TSH58p_10610 127f33bd0bf98ee2e0f8a272702be820 346 SUPERFAMILY SSF55781 75 345 6.47E-55 T 14-10-2018 TSH58p_10610 127f33bd0bf98ee2e0f8a272702be820 346 Gene3D G3DSA:3.30.450.40 109 343 5.0E-35 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_10610 127f33bd0bf98ee2e0f8a272702be820 346 PIRSF PIRSF005485 2 346 5.4E-109 T 14-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 TSH58p_10610 127f33bd0bf98ee2e0f8a272702be820 346 SUPERFAMILY SSF46785 4 85 3.53E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_10610 127f33bd0bf98ee2e0f8a272702be820 346 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 4 338 28.686 T 14-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 TSH58p_10610 127f33bd0bf98ee2e0f8a272702be820 346 Gene3D G3DSA:3.30.390.60 131 234 5.0E-35 T 14-10-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain superfamily TSH58p_10610 127f33bd0bf98ee2e0f8a272702be820 346 Pfam PF01628 HrcA protein C terminal domain 107 331 9.4E-57 T 14-10-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 TSH58p_10610 127f33bd0bf98ee2e0f8a272702be820 346 Gene3D G3DSA:1.10.10.10 1 87 6.2E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_10610 127f33bd0bf98ee2e0f8a272702be820 346 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 7 344 8.5E-97 T 14-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 TSH58p_11190 e4856a70bfab184e3ce0ee33b65a2f72 228 Gene3D G3DSA:3.40.50.10420 45 226 2.0E-43 T 14-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily TSH58p_11190 e4856a70bfab184e3ce0ee33b65a2f72 228 SUPERFAMILY SSF100950 47 227 2.59E-41 T 14-10-2018 IPR037171 NagB/RpiA transferase-like TSH58p_11190 e4856a70bfab184e3ce0ee33b65a2f72 228 Pfam PF02589 LUD domain 124 226 4.3E-27 T 14-10-2018 IPR003741 LUD domain TSH58p_08570 c67a0fbaf35480fef7e59647fd5e10d8 562 SMART SM00642 14 416 7.9E-91 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSH58p_08570 c67a0fbaf35480fef7e59647fd5e10d8 562 Gene3D G3DSA:2.60.40.1180 461 543 2.1E-10 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta TSH58p_08570 c67a0fbaf35480fef7e59647fd5e10d8 562 Pfam PF00128 Alpha amylase, catalytic domain 29 384 6.0E-73 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSH58p_08570 c67a0fbaf35480fef7e59647fd5e10d8 562 Gene3D G3DSA:3.90.400.10 104 173 7.4E-184 T 14-10-2018 TSH58p_08570 c67a0fbaf35480fef7e59647fd5e10d8 562 SUPERFAMILY SSF51011 461 542 6.77E-12 T 14-10-2018 TSH58p_08570 c67a0fbaf35480fef7e59647fd5e10d8 562 Gene3D G3DSA:3.20.20.80 6 456 7.4E-184 T 14-10-2018 TSH58p_08570 c67a0fbaf35480fef7e59647fd5e10d8 562 Pfam PF16657 Maltogenic Amylase, C-terminal domain 461 539 7.2E-8 T 14-10-2018 IPR032091 Maltogenic Amylase, C-terminal TSH58p_08570 c67a0fbaf35480fef7e59647fd5e10d8 562 SUPERFAMILY SSF51445 5 458 3.43E-114 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_26025 853f6c9685aedfdfe54cdab7f0419ab1 186 Gene3D G3DSA:1.10.10.10 79 122 1.5E-5 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_26025 853f6c9685aedfdfe54cdab7f0419ab1 186 Pfam PF02631 RecX family 62 179 1.0E-17 T 14-10-2018 IPR003783 Regulatory protein RecX GO:0006282 TSH58p_26025 853f6c9685aedfdfe54cdab7f0419ab1 186 Hamap MF_01114 Regulatory protein RecX [recX]. 12 184 11.191 T 14-10-2018 IPR003783 Regulatory protein RecX GO:0006282 TSH58p_04095 1079451a9ca7fa1a2dab5a2e7ff5e66f 342 Gene3D G3DSA:3.40.50.150 164 341 5.3E-35 T 14-10-2018 TSH58p_04095 1079451a9ca7fa1a2dab5a2e7ff5e66f 342 Pfam PF08468 Methyltransferase small domain N-terminal 67 159 1.4E-8 T 14-10-2018 IPR013675 Methyltransferase small, N-terminal GO:0006364|GO:0008990 TSH58p_04095 1079451a9ca7fa1a2dab5a2e7ff5e66f 342 Gene3D G3DSA:3.40.50.150 24 152 1.6E-9 T 14-10-2018 TSH58p_04095 1079451a9ca7fa1a2dab5a2e7ff5e66f 342 SUPERFAMILY SSF53335 182 309 1.96E-20 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_04095 1079451a9ca7fa1a2dab5a2e7ff5e66f 342 Pfam PF05175 Methyltransferase small domain 173 337 6.3E-37 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 TSH58p_09430 8daad85d5e3cfafd31eca70987b0297c 398 Pfam PF00549 CoA-ligase 271 391 2.5E-28 T 14-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSH58p_09430 8daad85d5e3cfafd31eca70987b0297c 398 SUPERFAMILY SSF52210 248 394 5.76E-57 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSH58p_09430 8daad85d5e3cfafd31eca70987b0297c 398 SUPERFAMILY SSF56059 1 247 3.72E-83 T 14-10-2018 TSH58p_09430 8daad85d5e3cfafd31eca70987b0297c 398 Gene3D G3DSA:3.30.1490.20 21 113 1.8E-94 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSH58p_09430 8daad85d5e3cfafd31eca70987b0297c 398 PIRSF PIRSF001554 1 397 4.1E-153 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSH58p_09430 8daad85d5e3cfafd31eca70987b0297c 398 Gene3D G3DSA:3.40.50.261 249 397 2.9E-61 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSH58p_09430 8daad85d5e3cfafd31eca70987b0297c 398 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 266 291 - T 14-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSH58p_09430 8daad85d5e3cfafd31eca70987b0297c 398 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 394 9.3E-162 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSH58p_09430 8daad85d5e3cfafd31eca70987b0297c 398 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 395 44.944 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSH58p_09430 8daad85d5e3cfafd31eca70987b0297c 398 Pfam PF08442 ATP-grasp domain 2 211 1.9E-77 T 14-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSH58p_09430 8daad85d5e3cfafd31eca70987b0297c 398 Gene3D G3DSA:3.30.470.20 1 243 1.8E-94 T 14-10-2018 TSH58p_03215 30447b1a3183317a49214947cdeabce7 193 SUPERFAMILY SSF46689 6 77 2.99E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_03215 30447b1a3183317a49214947cdeabce7 193 ProSitePatterns PS01081 TetR-type HTH domain signature. 25 55 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site TSH58p_03215 30447b1a3183317a49214947cdeabce7 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 2.5E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_03215 30447b1a3183317a49214947cdeabce7 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 2.5E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_03215 30447b1a3183317a49214947cdeabce7 193 SUPERFAMILY SSF48498 80 190 2.08E-7 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TSH58p_03215 30447b1a3183317a49214947cdeabce7 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 59 1.4E-18 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_03215 30447b1a3183317a49214947cdeabce7 193 Gene3D G3DSA:1.10.10.60 1 54 8.8E-18 T 14-10-2018 TSH58p_03215 30447b1a3183317a49214947cdeabce7 193 Gene3D G3DSA:1.10.357.10 55 189 6.0E-14 T 14-10-2018 TSH58p_23535 d30d9b67d4e59ba053bed4aa9ea3c0ff 584 SUPERFAMILY SSF55874 424 579 2.49E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_23535 d30d9b67d4e59ba053bed4aa9ea3c0ff 584 SMART SM00388 361 429 1.2E-7 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_23535 d30d9b67d4e59ba053bed4aa9ea3c0ff 584 PIRSF PIRSF036431 3 584 1.1E-178 T 14-10-2018 IPR017055 Signal transduction histidine kinase, DctB (C4-dicarboxylate transport system regulator) TSH58p_23535 d30d9b67d4e59ba053bed4aa9ea3c0ff 584 Gene3D G3DSA:1.10.287.130 338 424 8.8E-20 T 14-10-2018 TSH58p_23535 d30d9b67d4e59ba053bed4aa9ea3c0ff 584 SUPERFAMILY SSF47384 356 429 2.35E-11 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_23535 d30d9b67d4e59ba053bed4aa9ea3c0ff 584 Pfam PF00512 His Kinase A (phospho-acceptor) domain 361 428 5.4E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_23535 d30d9b67d4e59ba053bed4aa9ea3c0ff 584 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 473 579 9.9E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_23535 d30d9b67d4e59ba053bed4aa9ea3c0ff 584 SMART SM00387 471 581 4.2E-31 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_23535 d30d9b67d4e59ba053bed4aa9ea3c0ff 584 Gene3D G3DSA:3.30.450.20 59 183 1.1E-63 T 14-10-2018 TSH58p_23535 d30d9b67d4e59ba053bed4aa9ea3c0ff 584 Gene3D G3DSA:3.30.450.20 46 281 1.1E-63 T 14-10-2018 TSH58p_23535 d30d9b67d4e59ba053bed4aa9ea3c0ff 584 Gene3D G3DSA:3.30.565.10 433 583 1.7E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_23535 d30d9b67d4e59ba053bed4aa9ea3c0ff 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 541 559 4.9E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_23535 d30d9b67d4e59ba053bed4aa9ea3c0ff 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 510 524 4.9E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_23535 d30d9b67d4e59ba053bed4aa9ea3c0ff 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 565 578 4.9E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_23535 d30d9b67d4e59ba053bed4aa9ea3c0ff 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 528 538 4.9E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_23535 d30d9b67d4e59ba053bed4aa9ea3c0ff 584 Pfam PF02743 Cache domain 37 280 9.1E-12 T 14-10-2018 IPR033479 Double Cache domain 1 TSH58p_23535 d30d9b67d4e59ba053bed4aa9ea3c0ff 584 SUPERFAMILY SSF103190 58 194 1.2E-16 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily TSH58p_01825 7e883d8c5a8cbc697a56be6a4cc3d8bb 269 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_01825 7e883d8c5a8cbc697a56be6a4cc3d8bb 269 SMART SM00382 26 218 3.3E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_01825 7e883d8c5a8cbc697a56be6a4cc3d8bb 269 PIRSF PIRSF039085 1 246 4.0E-114 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 TSH58p_01825 7e883d8c5a8cbc697a56be6a4cc3d8bb 269 Gene3D G3DSA:3.40.50.300 1 264 2.7E-79 T 14-10-2018 TSH58p_01825 7e883d8c5a8cbc697a56be6a4cc3d8bb 269 Pfam PF00005 ABC transporter 17 170 3.4E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_01825 7e883d8c5a8cbc697a56be6a4cc3d8bb 269 SUPERFAMILY SSF52540 1 240 2.48E-79 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_24305 68344f27053fcc8a3c4316ec1a7b1272 139 SUPERFAMILY SSF47188 2 125 2.75E-29 T 14-10-2018 IPR035938 Hemerythrin-like superfamily TSH58p_24305 68344f27053fcc8a3c4316ec1a7b1272 139 Pfam PF01814 Hemerythrin HHE cation binding domain 13 120 1.1E-10 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 TSH58p_24305 68344f27053fcc8a3c4316ec1a7b1272 139 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 2 125 6.4E-31 T 14-10-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 TSH58p_24305 68344f27053fcc8a3c4316ec1a7b1272 139 Gene3D G3DSA:1.20.120.50 1 130 5.6E-31 T 14-10-2018 IPR035938 Hemerythrin-like superfamily TSH58p_24305 68344f27053fcc8a3c4316ec1a7b1272 139 ProSitePatterns PS00550 Hemerythrin family signature. 55 78 - T 14-10-2018 IPR016131 Haemerythrin, iron-binding site GO:0046872 TSH58p_05890 2ce8f90fefbcd15d952db66c58cc9964 430 Gene3D G3DSA:3.10.20.600 232 328 1.7E-43 T 14-10-2018 TSH58p_05890 2ce8f90fefbcd15d952db66c58cc9964 430 Pfam PF10531 SLBB domain 243 292 1.2E-9 T 14-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05890 2ce8f90fefbcd15d952db66c58cc9964 430 SUPERFAMILY SSF140490 327 423 1.44E-36 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05890 2ce8f90fefbcd15d952db66c58cc9964 430 SUPERFAMILY SSF142984 241 326 1.22E-24 T 14-10-2018 TSH58p_05890 2ce8f90fefbcd15d952db66c58cc9964 430 SMART SM00928 331 376 5.8E-26 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05890 2ce8f90fefbcd15d952db66c58cc9964 430 Gene3D G3DSA:1.20.1440.230 329 429 5.3E-39 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05890 2ce8f90fefbcd15d952db66c58cc9964 430 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 47 219 3.3E-50 T 14-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05890 2ce8f90fefbcd15d952db66c58cc9964 430 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 333 415 3.5E-30 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05890 2ce8f90fefbcd15d952db66c58cc9964 430 Gene3D G3DSA:3.40.50.11540 52 230 1.0E-83 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05890 2ce8f90fefbcd15d952db66c58cc9964 430 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 8 417 5.8E-199 T 14-10-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05890 2ce8f90fefbcd15d952db66c58cc9964 430 SUPERFAMILY SSF142019 3 240 2.09E-86 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05890 2ce8f90fefbcd15d952db66c58cc9964 430 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 344 355 - T 14-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05890 2ce8f90fefbcd15d952db66c58cc9964 430 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 167 182 - T 14-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_04805 ad061a0dc4bd3faa8c37b42f91359b1f 366 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 87 97 9.5E-23 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_04805 ad061a0dc4bd3faa8c37b42f91359b1f 366 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 327 342 9.5E-23 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_04805 ad061a0dc4bd3faa8c37b42f91359b1f 366 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 25 41 9.5E-23 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_04805 ad061a0dc4bd3faa8c37b42f91359b1f 366 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 66 84 9.5E-23 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_04805 ad061a0dc4bd3faa8c37b42f91359b1f 366 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 47 63 9.5E-23 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_04805 ad061a0dc4bd3faa8c37b42f91359b1f 366 Gene3D G3DSA:3.40.50.2300 32 343 7.6E-118 T 14-10-2018 TSH58p_04805 ad061a0dc4bd3faa8c37b42f91359b1f 366 SUPERFAMILY SSF53822 24 365 2.55E-94 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_04805 ad061a0dc4bd3faa8c37b42f91359b1f 366 Pfam PF13458 Periplasmic binding protein 25 361 1.0E-56 T 14-10-2018 IPR028081 Leucine-binding protein domain TSH58p_04805 ad061a0dc4bd3faa8c37b42f91359b1f 366 Gene3D G3DSA:3.40.50.2300 143 271 7.6E-118 T 14-10-2018 TSH58p_18740 87c4e779ee3e714f3f6b87f17017858d 479 TIGRFAM TIGR00400 mgtE: magnesium transporter 49 478 3.4E-91 T 14-10-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 TSH58p_18740 87c4e779ee3e714f3f6b87f17017858d 479 SUPERFAMILY SSF158791 39 164 1.44E-30 T 14-10-2018 TSH58p_18740 87c4e779ee3e714f3f6b87f17017858d 479 Pfam PF03448 MgtE intracellular N domain 64 164 4.8E-25 T 14-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain TSH58p_18740 87c4e779ee3e714f3f6b87f17017858d 479 Gene3D G3DSA:3.10.580.10 163 291 1.1E-38 T 14-10-2018 TSH58p_18740 87c4e779ee3e714f3f6b87f17017858d 479 SUPERFAMILY SSF161093 308 478 1.57E-49 T 14-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 TSH58p_18740 87c4e779ee3e714f3f6b87f17017858d 479 SMART SM00924 64 167 1.6E-31 T 14-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain TSH58p_18740 87c4e779ee3e714f3f6b87f17017858d 479 Gene3D G3DSA:1.25.60.10 36 162 3.5E-23 T 14-10-2018 IPR038076 MgtE, N-terminal domain superfamily TSH58p_18740 87c4e779ee3e714f3f6b87f17017858d 479 SMART SM00116 239 287 3.4E-9 T 14-10-2018 IPR000644 CBS domain TSH58p_18740 87c4e779ee3e714f3f6b87f17017858d 479 Pfam PF00571 CBS domain 233 286 4.4E-7 T 14-10-2018 IPR000644 CBS domain TSH58p_18740 87c4e779ee3e714f3f6b87f17017858d 479 Pfam PF01769 Divalent cation transporter 351 471 2.6E-26 T 14-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 TSH58p_18740 87c4e779ee3e714f3f6b87f17017858d 479 SUPERFAMILY SSF54631 166 301 9.69E-26 T 14-10-2018 TSH58p_18740 87c4e779ee3e714f3f6b87f17017858d 479 Gene3D G3DSA:1.10.357.20 304 478 4.2E-51 T 14-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain TSH58p_10750 254c26eeb0f076974270555784b98cca 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 140 161 1.5E-26 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TSH58p_10750 254c26eeb0f076974270555784b98cca 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 194 204 1.5E-26 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TSH58p_10750 254c26eeb0f076974270555784b98cca 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 14 30 1.5E-26 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TSH58p_10750 254c26eeb0f076974270555784b98cca 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 64 83 1.5E-26 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TSH58p_10750 254c26eeb0f076974270555784b98cca 332 Gene3D G3DSA:1.10.240.10 187 299 5.9E-133 T 14-10-2018 TSH58p_10750 254c26eeb0f076974270555784b98cca 332 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 1 330 38.845 T 14-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 TSH58p_10750 254c26eeb0f076974270555784b98cca 332 Pfam PF00579 tRNA synthetases class I (W and Y) 3 270 4.0E-78 T 14-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_10750 254c26eeb0f076974270555784b98cca 332 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 3 329 1.2E-96 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TSH58p_10750 254c26eeb0f076974270555784b98cca 332 SUPERFAMILY SSF52374 3 329 1.86E-93 T 14-10-2018 TSH58p_10750 254c26eeb0f076974270555784b98cca 332 Gene3D G3DSA:3.40.50.620 4 328 5.9E-133 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_15885 c1f2f2d35de7703bdc3de121a2917284 358 Pfam PF01264 Chorismate synthase 10 350 3.5E-141 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TSH58p_15885 c1f2f2d35de7703bdc3de121a2917284 358 Gene3D G3DSA:3.60.150.10 1 357 1.7E-151 T 14-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TSH58p_15885 c1f2f2d35de7703bdc3de121a2917284 358 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TSH58p_15885 c1f2f2d35de7703bdc3de121a2917284 358 TIGRFAM TIGR00033 aroC: chorismate synthase 10 354 1.9E-139 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TSH58p_15885 c1f2f2d35de7703bdc3de121a2917284 358 ProSitePatterns PS00789 Chorismate synthase signature 3. 324 340 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TSH58p_15885 c1f2f2d35de7703bdc3de121a2917284 358 PIRSF PIRSF001456 3 357 5.5E-142 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TSH58p_15885 c1f2f2d35de7703bdc3de121a2917284 358 Hamap MF_00300 Chorismate synthase [aroC]. 10 357 37.642 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TSH58p_15885 c1f2f2d35de7703bdc3de121a2917284 358 SUPERFAMILY SSF103263 4 354 4.84E-147 T 14-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TSH58p_15885 c1f2f2d35de7703bdc3de121a2917284 358 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TSH58p_22240 71ef5cdcbfdc499cfc38baca33b21616 219 Gene3D G3DSA:2.60.40.420 88 218 3.0E-23 T 14-10-2018 IPR008972 Cupredoxin TSH58p_22240 71ef5cdcbfdc499cfc38baca33b21616 219 SUPERFAMILY SSF49503 109 218 3.24E-17 T 14-10-2018 IPR008972 Cupredoxin TSH58p_24755 4c01a9d55ea204d34ac58d9b2a55d43a 768 PRINTS PR00344 Bacterial sensor protein C-terminal signature 534 548 4.8E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_24755 4c01a9d55ea204d34ac58d9b2a55d43a 768 PRINTS PR00344 Bacterial sensor protein C-terminal signature 565 583 4.8E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_24755 4c01a9d55ea204d34ac58d9b2a55d43a 768 PRINTS PR00344 Bacterial sensor protein C-terminal signature 589 602 4.8E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_24755 4c01a9d55ea204d34ac58d9b2a55d43a 768 PRINTS PR00344 Bacterial sensor protein C-terminal signature 552 562 4.8E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_24755 4c01a9d55ea204d34ac58d9b2a55d43a 768 Pfam PF00512 His Kinase A (phospho-acceptor) domain 381 446 1.0E-18 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_24755 4c01a9d55ea204d34ac58d9b2a55d43a 768 Gene3D G3DSA:3.30.565.10 447 607 8.8E-51 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_24755 4c01a9d55ea204d34ac58d9b2a55d43a 768 SMART SM00448 629 743 5.8E-33 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_24755 4c01a9d55ea204d34ac58d9b2a55d43a 768 SUPERFAMILY SSF47384 366 447 7.06E-21 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_24755 4c01a9d55ea204d34ac58d9b2a55d43a 768 Pfam PF02743 Cache domain 69 233 6.5E-16 T 14-10-2018 IPR033479 Double Cache domain 1 TSH58p_24755 4c01a9d55ea204d34ac58d9b2a55d43a 768 Gene3D G3DSA:1.10.287.130 371 446 4.5E-25 T 14-10-2018 TSH58p_24755 4c01a9d55ea204d34ac58d9b2a55d43a 768 SUPERFAMILY SSF52172 628 748 1.85E-34 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_24755 4c01a9d55ea204d34ac58d9b2a55d43a 768 Pfam PF00072 Response regulator receiver domain 631 743 1.8E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_24755 4c01a9d55ea204d34ac58d9b2a55d43a 768 Gene3D G3DSA:3.30.450.20 197 276 6.6E-6 T 14-10-2018 TSH58p_24755 4c01a9d55ea204d34ac58d9b2a55d43a 768 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 493 604 1.8E-32 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_24755 4c01a9d55ea204d34ac58d9b2a55d43a 768 SUPERFAMILY SSF158472 316 363 2.48E-5 T 14-10-2018 TSH58p_24755 4c01a9d55ea204d34ac58d9b2a55d43a 768 SMART SM00304 313 366 1.5E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_24755 4c01a9d55ea204d34ac58d9b2a55d43a 768 Gene3D G3DSA:1.20.1480.50 280 370 9.8E-8 T 14-10-2018 TSH58p_24755 4c01a9d55ea204d34ac58d9b2a55d43a 768 SMART SM00388 381 446 5.0E-25 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_24755 4c01a9d55ea204d34ac58d9b2a55d43a 768 SMART SM00387 493 605 4.7E-42 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_24755 4c01a9d55ea204d34ac58d9b2a55d43a 768 Gene3D G3DSA:3.30.450.20 42 188 1.9E-19 T 14-10-2018 TSH58p_24755 4c01a9d55ea204d34ac58d9b2a55d43a 768 Pfam PF00672 HAMP domain 319 363 6.8E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_24755 4c01a9d55ea204d34ac58d9b2a55d43a 768 Gene3D G3DSA:3.40.50.12740 628 767 7.2E-38 T 14-10-2018 TSH58p_24755 4c01a9d55ea204d34ac58d9b2a55d43a 768 SUPERFAMILY SSF55874 435 607 4.19E-47 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_25995 805b1ae4d9b1b1a12e6fd86f26120d5c 619 ProSitePatterns PS00211 ABC transporters family signature. 504 518 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_25995 805b1ae4d9b1b1a12e6fd86f26120d5c 619 Pfam PF00664 ABC transporter transmembrane region 47 321 1.7E-40 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TSH58p_25995 805b1ae4d9b1b1a12e6fd86f26120d5c 619 SUPERFAMILY SSF52540 357 602 1.94E-92 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_25995 805b1ae4d9b1b1a12e6fd86f26120d5c 619 SMART SM00382 392 578 8.3E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_25995 805b1ae4d9b1b1a12e6fd86f26120d5c 619 Gene3D G3DSA:1.20.1560.10 33 355 2.5E-126 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_25995 805b1ae4d9b1b1a12e6fd86f26120d5c 619 Pfam PF00005 ABC transporter 383 532 1.4E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_25995 805b1ae4d9b1b1a12e6fd86f26120d5c 619 Gene3D G3DSA:3.40.50.300 357 611 4.7E-95 T 14-10-2018 TSH58p_25995 805b1ae4d9b1b1a12e6fd86f26120d5c 619 SUPERFAMILY SSF90123 30 350 3.79E-62 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_04310 c157b09503c9ee8e18bf7c1d8235fefc 399 SUPERFAMILY SSF161098 190 383 8.5E-26 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_04310 c157b09503c9ee8e18bf7c1d8235fefc 399 SUPERFAMILY SSF161098 91 158 6.87E-13 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_04310 c157b09503c9ee8e18bf7c1d8235fefc 399 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 90 155 2.3E-16 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 TSH58p_04310 c157b09503c9ee8e18bf7c1d8235fefc 399 Gene3D G3DSA:1.10.3720.10 186 395 1.0E-32 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_04310 c157b09503c9ee8e18bf7c1d8235fefc 399 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 394 9.3E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_04310 c157b09503c9ee8e18bf7c1d8235fefc 399 Gene3D G3DSA:1.10.3720.10 86 183 5.1E-8 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_02985 adc784217096061700a5fb298233bd7b 398 PIRSF PIRSF028704 1 384 4.3E-125 T 14-10-2018 IPR014550 Uncharacterised conserved protein UCP028704, OpgC TSH58p_02985 adc784217096061700a5fb298233bd7b 398 Pfam PF10129 OpgC protein 7 363 1.2E-118 T 14-10-2018 IPR014550 Uncharacterised conserved protein UCP028704, OpgC TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 707 725 - T 14-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 760 772 1.6E-18 T 14-10-2018 TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 707 722 1.6E-18 T 14-10-2018 TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 559 578 1.6E-18 T 14-10-2018 TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 724 739 1.6E-18 T 14-10-2018 TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 Gene3D G3DSA:3.50.30.10 274 498 1.1E-67 T 14-10-2018 TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 140 7.3E-30 T 14-10-2018 IPR002178 PTS EIIA type-2 domain TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 Gene3D G3DSA:3.40.930.10 1 142 5.6E-37 T 14-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 196 211 - T 14-10-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 PRINTS PR00107 Phosphocarrier protein signature 195 210 3.3E-15 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 PRINTS PR00107 Phosphocarrier protein signature 170 186 3.3E-15 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 PRINTS PR00107 Phosphocarrier protein signature 210 227 3.3E-15 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 SUPERFAMILY SSF51621 523 809 6.28E-97 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 Gene3D G3DSA:3.20.20.60 499 832 4.7E-111 T 14-10-2018 TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 166 239 4.9E-21 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 47 63 - T 14-10-2018 IPR002178 PTS EIIA type-2 domain TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 170 177 - T 14-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 SUPERFAMILY SSF47831 299 407 2.22E-27 T 14-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 Pfam PF00381 PTS HPr component phosphorylation site 163 239 4.0E-22 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 Pfam PF05524 PEP-utilising enzyme, N-terminal 274 392 1.2E-25 T 14-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 SUPERFAMILY SSF52009 392 503 3.53E-28 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 450 461 - T 14-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 Gene3D G3DSA:3.30.1340.10 160 244 3.8E-24 T 14-10-2018 IPR035895 HPr-like superfamily TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 SUPERFAMILY SSF55804 4 141 6.15E-37 T 14-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 272 825 1.6E-154 T 14-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 Pfam PF00391 PEP-utilising enzyme, mobile domain 420 491 3.3E-20 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 Gene3D G3DSA:1.10.274.10 291 412 1.1E-67 T 14-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 522 800 5.0E-106 T 14-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 TSH58p_21035 efa1a88369fa868e9184fc91bdad0e18 836 SUPERFAMILY SSF55594 163 244 5.63E-23 T 14-10-2018 IPR035895 HPr-like superfamily TSH58p_11960 44696b3290856784997a3ee14329cbea 492 Hamap MF_00484 Glycogen synthase [glgA]. 1 486 45.323 T 14-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 TSH58p_11960 44696b3290856784997a3ee14329cbea 492 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 1 485 3.7E-161 T 14-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 TSH58p_11960 44696b3290856784997a3ee14329cbea 492 SUPERFAMILY SSF53756 3 488 9.42E-120 T 14-10-2018 TSH58p_11960 44696b3290856784997a3ee14329cbea 492 Pfam PF00534 Glycosyl transferases group 1 300 458 1.5E-11 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 TSH58p_11960 44696b3290856784997a3ee14329cbea 492 Pfam PF08323 Starch synthase catalytic domain 2 245 1.6E-71 T 14-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 TSH58p_11960 44696b3290856784997a3ee14329cbea 492 Gene3D G3DSA:3.40.50.2000 3 483 3.2E-173 T 14-10-2018 TSH58p_11960 44696b3290856784997a3ee14329cbea 492 Gene3D G3DSA:3.40.50.2000 259 468 3.2E-173 T 14-10-2018 TSH58p_28680 8efad4958062c84f3620f83c8c82d1fa 350 Pfam PF00356 Bacterial regulatory proteins, lacI family 14 59 9.1E-16 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TSH58p_28680 8efad4958062c84f3620f83c8c82d1fa 350 Gene3D G3DSA:3.40.50.2300 70 160 2.5E-19 T 14-10-2018 TSH58p_28680 8efad4958062c84f3620f83c8c82d1fa 350 Gene3D G3DSA:3.40.50.2300 166 340 1.7E-51 T 14-10-2018 TSH58p_28680 8efad4958062c84f3620f83c8c82d1fa 350 SUPERFAMILY SSF53822 72 341 3.77E-72 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_28680 8efad4958062c84f3620f83c8c82d1fa 350 SUPERFAMILY SSF47413 12 70 1.05E-16 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_28680 8efad4958062c84f3620f83c8c82d1fa 350 ProSitePatterns PS00356 LacI-type HTH domain signature. 15 33 - T 14-10-2018 TSH58p_28680 8efad4958062c84f3620f83c8c82d1fa 350 Gene3D G3DSA:1.10.260.40 7 69 7.5E-20 T 14-10-2018 TSH58p_28680 8efad4958062c84f3620f83c8c82d1fa 350 Pfam PF13377 Periplasmic binding protein-like domain 180 339 2.6E-39 T 14-10-2018 TSH58p_28680 8efad4958062c84f3620f83c8c82d1fa 350 SMART SM00354 12 82 9.7E-26 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TSH58p_30465 9cabf6d669a8ed1f7c2c72c2f4e024a2 996 TIGRFAM TIGR01372 soxA: sarcosine oxidase, alpha subunit family 5 995 0.0 T 14-10-2018 IPR006277 Sarcosine oxidase, alpha subunit GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 TSH58p_30465 9cabf6d669a8ed1f7c2c72c2f4e024a2 996 Pfam PF01571 Aminomethyltransferase folate-binding domain 614 876 2.2E-67 T 14-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain TSH58p_30465 9cabf6d669a8ed1f7c2c72c2f4e024a2 996 Gene3D G3DSA:3.50.50.60 171 587 2.7E-97 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_30465 9cabf6d669a8ed1f7c2c72c2f4e024a2 996 PIRSF PIRSF037980 1 996 0.0 T 14-10-2018 IPR006277 Sarcosine oxidase, alpha subunit GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 TSH58p_30465 9cabf6d669a8ed1f7c2c72c2f4e024a2 996 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 171 423 5.7E-12 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSH58p_30465 9cabf6d669a8ed1f7c2c72c2f4e024a2 996 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 277 285 3.1E-11 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_30465 9cabf6d669a8ed1f7c2c72c2f4e024a2 996 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 366 382 3.1E-11 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_30465 9cabf6d669a8ed1f7c2c72c2f4e024a2 996 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 171 193 3.1E-11 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_30465 9cabf6d669a8ed1f7c2c72c2f4e024a2 996 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 316 340 3.1E-11 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_30465 9cabf6d669a8ed1f7c2c72c2f4e024a2 996 SUPERFAMILY SSF101790 897 994 3.76E-18 T 14-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal TSH58p_30465 9cabf6d669a8ed1f7c2c72c2f4e024a2 996 Gene3D G3DSA:3.50.50.60 288 417 2.7E-97 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_30465 9cabf6d669a8ed1f7c2c72c2f4e024a2 996 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 18 97 8.7E-18 T 14-10-2018 TSH58p_30465 9cabf6d669a8ed1f7c2c72c2f4e024a2 996 SUPERFAMILY SSF103025 606 896 1.57E-85 T 14-10-2018 TSH58p_30465 9cabf6d669a8ed1f7c2c72c2f4e024a2 996 Gene3D G3DSA:3.10.20.440 13 75 4.9E-6 T 14-10-2018 TSH58p_30465 9cabf6d669a8ed1f7c2c72c2f4e024a2 996 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 276 294 1.6E-9 T 14-10-2018 TSH58p_30465 9cabf6d669a8ed1f7c2c72c2f4e024a2 996 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 191 1.6E-9 T 14-10-2018 TSH58p_30465 9cabf6d669a8ed1f7c2c72c2f4e024a2 996 Gene3D G3DSA:3.30.1360.120 602 986 5.2E-93 T 14-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 TSH58p_30465 9cabf6d669a8ed1f7c2c72c2f4e024a2 996 SUPERFAMILY SSF51905 160 478 2.04E-30 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_30465 9cabf6d669a8ed1f7c2c72c2f4e024a2 996 Gene3D G3DSA:1.10.10.1100 504 580 2.7E-97 T 14-10-2018 TSH58p_30465 9cabf6d669a8ed1f7c2c72c2f4e024a2 996 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 885 983 2.2E-17 T 14-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 TSH58p_16170 141cf0993fa598bc75f5ed1d1490a922 439 SUPERFAMILY SSF103088 302 435 1.31E-29 T 14-10-2018 IPR036737 OmpA-like domain superfamily TSH58p_16170 141cf0993fa598bc75f5ed1d1490a922 439 Pfam PF00691 OmpA family 325 430 4.0E-19 T 14-10-2018 IPR006665 OmpA-like domain TSH58p_16170 141cf0993fa598bc75f5ed1d1490a922 439 Gene3D G3DSA:3.30.1330.60 246 439 1.4E-43 T 14-10-2018 IPR036737 OmpA-like domain superfamily TSH58p_23565 865ac230f7f43198b151dc68eb6a7189 510 Gene3D G3DSA:3.90.226.10 1 255 4.9E-96 T 14-10-2018 TSH58p_23565 865ac230f7f43198b151dc68eb6a7189 510 Pfam PF01039 Carboxyl transferase domain 27 508 4.1E-200 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 TSH58p_23565 865ac230f7f43198b151dc68eb6a7189 510 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 163 180 6.0E-5 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSH58p_23565 865ac230f7f43198b151dc68eb6a7189 510 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 127 145 6.0E-5 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSH58p_23565 865ac230f7f43198b151dc68eb6a7189 510 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 93 107 6.0E-5 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSH58p_23565 865ac230f7f43198b151dc68eb6a7189 510 SUPERFAMILY SSF52096 4 249 1.19E-79 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_23565 865ac230f7f43198b151dc68eb6a7189 510 SUPERFAMILY SSF52096 252 510 3.73E-90 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_23565 865ac230f7f43198b151dc68eb6a7189 510 Gene3D G3DSA:3.90.226.10 257 510 1.5E-95 T 14-10-2018 TSH58p_24865 a55e03552da84325d91fd83220dd1504 481 Pfam PF02397 Bacterial sugar transferase 285 476 3.2E-59 T 14-10-2018 IPR003362 Bacterial sugar transferase TSH58p_24865 a55e03552da84325d91fd83220dd1504 481 SUPERFAMILY SSF51735 154 233 1.38E-7 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_24865 a55e03552da84325d91fd83220dd1504 481 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 32 480 9.9E-98 T 14-10-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase TSH58p_24865 a55e03552da84325d91fd83220dd1504 481 Pfam PF13727 CoA-binding domain 77 210 3.9E-9 T 14-10-2018 TSH58p_24865 a55e03552da84325d91fd83220dd1504 481 Gene3D G3DSA:3.40.50.720 151 251 1.2E-11 T 14-10-2018 TSH58p_25225 0eb9c5d9496cfad9a68b303a0a9fd564 157 Pfam PF05433 Glycine zipper 2TM domain 30 71 5.3E-8 T 14-10-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 TSH58p_25225 0eb9c5d9496cfad9a68b303a0a9fd564 157 PIRSF PIRSF002721 1 157 1.4E-35 T 14-10-2018 IPR016364 Surface antigen, Rickettsia type TSH58p_25225 0eb9c5d9496cfad9a68b303a0a9fd564 157 Pfam PF16998 17 kDa outer membrane surface antigen 75 157 4.2E-13 T 14-10-2018 IPR032635 Surface antigen domain TSH58p_02580 d4825b6380c9565e8a2dd0180a1f736d 668 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 291 345 - T 14-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_02580 d4825b6380c9565e8a2dd0180a1f736d 668 Gene3D G3DSA:1.20.210.10 28 577 6.9E-189 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_02580 d4825b6380c9565e8a2dd0180a1f736d 668 SUPERFAMILY SSF81442 54 571 1.57E-177 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_02580 d4825b6380c9565e8a2dd0180a1f736d 668 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 67 515 7.6E-138 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_02580 d4825b6380c9565e8a2dd0180a1f736d 668 PRINTS PR01165 Cytochrome c oxidase subunit I signature 472 493 8.8E-91 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_02580 d4825b6380c9565e8a2dd0180a1f736d 668 PRINTS PR01165 Cytochrome c oxidase subunit I signature 289 310 8.8E-91 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_02580 d4825b6380c9565e8a2dd0180a1f736d 668 PRINTS PR01165 Cytochrome c oxidase subunit I signature 422 441 8.8E-91 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_02580 d4825b6380c9565e8a2dd0180a1f736d 668 PRINTS PR01165 Cytochrome c oxidase subunit I signature 394 412 8.8E-91 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_02580 d4825b6380c9565e8a2dd0180a1f736d 668 PRINTS PR01165 Cytochrome c oxidase subunit I signature 238 257 8.8E-91 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_02580 d4825b6380c9565e8a2dd0180a1f736d 668 PRINTS PR01165 Cytochrome c oxidase subunit I signature 177 189 8.8E-91 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_02580 d4825b6380c9565e8a2dd0180a1f736d 668 PRINTS PR01165 Cytochrome c oxidase subunit I signature 359 380 8.8E-91 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_02580 d4825b6380c9565e8a2dd0180a1f736d 668 PRINTS PR01165 Cytochrome c oxidase subunit I signature 135 159 8.8E-91 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_02580 d4825b6380c9565e8a2dd0180a1f736d 668 PRINTS PR01165 Cytochrome c oxidase subunit I signature 209 227 8.8E-91 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_02580 d4825b6380c9565e8a2dd0180a1f736d 668 PRINTS PR01165 Cytochrome c oxidase subunit I signature 58 83 8.8E-91 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_02580 d4825b6380c9565e8a2dd0180a1f736d 668 PRINTS PR01165 Cytochrome c oxidase subunit I signature 108 131 8.8E-91 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_02580 d4825b6380c9565e8a2dd0180a1f736d 668 PRINTS PR01165 Cytochrome c oxidase subunit I signature 335 350 8.8E-91 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_02580 d4825b6380c9565e8a2dd0180a1f736d 668 TIGRFAM TIGR02843 CyoB: cytochrome o ubiquinol oxidase, subunit I 13 657 0.0 T 14-10-2018 IPR014207 Cytochrome o ubiquinol oxidase, subunit I GO:0016682|GO:0055114 MetaCyc: PWY-7544 TSH58p_16805 4e1644294770e2cf67c0cac1a3946c77 683 Gene3D G3DSA:3.40.50.740 73 476 3.2E-114 T 14-10-2018 TSH58p_16805 4e1644294770e2cf67c0cac1a3946c77 683 SMART SM00926 3 59 2.8E-10 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_16805 4e1644294770e2cf67c0cac1a3946c77 683 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 7 58 4.4E-6 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_16805 4e1644294770e2cf67c0cac1a3946c77 683 Gene3D G3DSA:3.40.228.10 139 353 3.2E-114 T 14-10-2018 TSH58p_16805 4e1644294770e2cf67c0cac1a3946c77 683 Gene3D G3DSA:2.40.40.20 547 683 7.9E-23 T 14-10-2018 TSH58p_16805 4e1644294770e2cf67c0cac1a3946c77 683 Pfam PF00384 Molybdopterin oxidoreductase 62 471 1.9E-47 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_16805 4e1644294770e2cf67c0cac1a3946c77 683 SUPERFAMILY SSF50692 560 682 3.62E-30 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TSH58p_16805 4e1644294770e2cf67c0cac1a3946c77 683 Gene3D G3DSA:3.30.2070.10 431 512 3.2E-114 T 14-10-2018 TSH58p_16805 4e1644294770e2cf67c0cac1a3946c77 683 Gene3D G3DSA:2.20.25.90 3 64 4.1E-7 T 14-10-2018 TSH58p_16805 4e1644294770e2cf67c0cac1a3946c77 683 Pfam PF01568 Molydopterin dinucleotide binding domain 567 676 7.7E-19 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TSH58p_16805 4e1644294770e2cf67c0cac1a3946c77 683 SUPERFAMILY SSF53706 7 568 6.15E-140 T 14-10-2018 TSH58p_28790 4edd974feef16d4bf74387a73f335d76 383 Hamap MF_00296 Homoserine O-acetyltransferase [metXA]. 2 369 31.8 T 14-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 TSH58p_28790 4edd974feef16d4bf74387a73f335d76 383 PIRSF PIRSF000443 2 378 2.9E-139 T 14-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 TSH58p_28790 4edd974feef16d4bf74387a73f335d76 383 SUPERFAMILY SSF53474 11 369 3.38E-104 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_28790 4edd974feef16d4bf74387a73f335d76 383 Pfam PF00561 alpha/beta hydrolase fold 41 356 9.1E-30 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_28790 4edd974feef16d4bf74387a73f335d76 383 Gene3D G3DSA:3.40.50.1820 16 357 1.0E-139 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_28790 4edd974feef16d4bf74387a73f335d76 383 Gene3D G3DSA:1.10.1740.110 176 282 1.0E-139 T 14-10-2018 TSH58p_28790 4edd974feef16d4bf74387a73f335d76 383 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 12 368 7.2E-143 T 14-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 TSH58p_21735 e273f04ba50a8448a7dd75ffdb339177 249 Pfam PF01925 Sulfite exporter TauE/SafE 13 242 4.1E-27 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TSH58p_08215 205a5bf9697164d979fc0886fb8cb0cc 377 Gene3D G3DSA:2.40.50.100 4 105 2.0E-21 T 14-10-2018 TSH58p_08215 205a5bf9697164d979fc0886fb8cb0cc 377 Pfam PF12697 Alpha/beta hydrolase family 139 367 1.1E-26 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_08215 205a5bf9697164d979fc0886fb8cb0cc 377 PRINTS PR00111 Alpha/beta hydrolase fold signature 322 336 8.0E-17 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_08215 205a5bf9697164d979fc0886fb8cb0cc 377 PRINTS PR00111 Alpha/beta hydrolase fold signature 206 219 8.0E-17 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_08215 205a5bf9697164d979fc0886fb8cb0cc 377 PRINTS PR00111 Alpha/beta hydrolase fold signature 220 233 8.0E-17 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_08215 205a5bf9697164d979fc0886fb8cb0cc 377 PRINTS PR00111 Alpha/beta hydrolase fold signature 162 177 8.0E-17 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_08215 205a5bf9697164d979fc0886fb8cb0cc 377 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 33 62 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 TSH58p_08215 205a5bf9697164d979fc0886fb8cb0cc 377 SUPERFAMILY SSF53474 114 372 2.03E-57 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_08215 205a5bf9697164d979fc0886fb8cb0cc 377 SUPERFAMILY SSF51230 8 97 8.64E-21 T 14-10-2018 IPR011053 Single hybrid motif TSH58p_08215 205a5bf9697164d979fc0886fb8cb0cc 377 Gene3D G3DSA:3.40.50.1820 108 377 6.7E-63 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_08215 205a5bf9697164d979fc0886fb8cb0cc 377 Pfam PF00364 Biotin-requiring enzyme 10 81 5.0E-13 T 14-10-2018 IPR000089 Biotin/lipoyl attachment TSH58p_27670 e1ea8acde52c7d801ea0403fd1d6009c 364 SMART SM00382 38 225 4.6E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_27670 e1ea8acde52c7d801ea0403fd1d6009c 364 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_27670 e1ea8acde52c7d801ea0403fd1d6009c 364 SUPERFAMILY SSF52540 14 251 4.78E-79 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_27670 e1ea8acde52c7d801ea0403fd1d6009c 364 Pfam PF08402 TOBE domain 291 359 2.6E-7 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TSH58p_27670 e1ea8acde52c7d801ea0403fd1d6009c 364 SUPERFAMILY SSF50331 260 359 4.08E-9 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSH58p_27670 e1ea8acde52c7d801ea0403fd1d6009c 364 Pfam PF00005 ABC transporter 30 175 3.1E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_27670 e1ea8acde52c7d801ea0403fd1d6009c 364 Gene3D G3DSA:3.40.50.300 12 258 2.1E-69 T 14-10-2018 TSH58p_21080 be991af743f15317c3adb39fb3923e63 294 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 110 269 2.1E-72 T 14-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 TSH58p_21080 be991af743f15317c3adb39fb3923e63 294 Gene3D G3DSA:1.10.3130.10 25 169 3.7E-46 T 14-10-2018 TSH58p_21080 be991af743f15317c3adb39fb3923e63 294 SMART SM00971 36 140 3.2E-36 T 14-10-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 TSH58p_21080 be991af743f15317c3adb39fb3923e63 294 Pfam PF06426 Serine acetyltransferase, N-terminal 36 139 1.0E-31 T 14-10-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 TSH58p_21080 be991af743f15317c3adb39fb3923e63 294 Gene3D G3DSA:2.160.10.10 170 290 5.7E-36 T 14-10-2018 TSH58p_21080 be991af743f15317c3adb39fb3923e63 294 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 220 254 1.6E-6 T 14-10-2018 IPR001451 Hexapeptide repeat TSH58p_21080 be991af743f15317c3adb39fb3923e63 294 PIRSF PIRSF000441 103 291 8.2E-66 T 14-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 TSH58p_21080 be991af743f15317c3adb39fb3923e63 294 SUPERFAMILY SSF51161 34 271 4.02E-58 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily TSH58p_07580 304fcae61533f04c508e2f115e54f0c1 383 Pfam PF00266 Aminotransferase class-V 2 369 3.4E-71 T 14-10-2018 IPR000192 Aminotransferase class V domain TSH58p_07580 304fcae61533f04c508e2f115e54f0c1 383 Gene3D G3DSA:3.40.640.10 59 235 4.2E-133 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_07580 304fcae61533f04c508e2f115e54f0c1 383 PIRSF PIRSF005572 1 382 5.3E-122 T 14-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 TSH58p_07580 304fcae61533f04c508e2f115e54f0c1 383 Gene3D G3DSA:3.90.1150.10 2 373 4.2E-133 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_07580 304fcae61533f04c508e2f115e54f0c1 383 Gene3D G3DSA:1.10.260.50 13 278 4.2E-133 T 14-10-2018 TSH58p_07580 304fcae61533f04c508e2f115e54f0c1 383 SUPERFAMILY SSF53383 1 377 1.05E-93 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_16455 3d8a5eb7c91d38b1f88bb4fca702fa98 270 Gene3D G3DSA:3.40.190.10 126 229 4.4E-11 T 14-10-2018 TSH58p_16455 3d8a5eb7c91d38b1f88bb4fca702fa98 270 SUPERFAMILY SSF53850 46 264 1.09E-20 T 14-10-2018 TSH58p_16455 3d8a5eb7c91d38b1f88bb4fca702fa98 270 SMART SM00062 45 270 0.0052 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_16455 3d8a5eb7c91d38b1f88bb4fca702fa98 270 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 74 262 1.6E-8 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_16455 3d8a5eb7c91d38b1f88bb4fca702fa98 270 Gene3D G3DSA:3.40.190.10 52 263 4.4E-11 T 14-10-2018 TSH58p_21380 74ad83b73fee92691c155f3f8144da3e 527 SUPERFAMILY SSF52540 258 505 2.19E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_21380 74ad83b73fee92691c155f3f8144da3e 527 SUPERFAMILY SSF52540 13 239 6.02E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_21380 74ad83b73fee92691c155f3f8144da3e 527 Gene3D G3DSA:3.40.50.300 9 252 1.2E-53 T 14-10-2018 TSH58p_21380 74ad83b73fee92691c155f3f8144da3e 527 Pfam PF00005 ABC transporter 290 445 1.1E-15 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_21380 74ad83b73fee92691c155f3f8144da3e 527 SMART SM00382 298 494 3.0E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_21380 74ad83b73fee92691c155f3f8144da3e 527 SMART SM00382 39 229 6.9E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_21380 74ad83b73fee92691c155f3f8144da3e 527 ProSitePatterns PS00211 ABC transporters family signature. 418 432 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_21380 74ad83b73fee92691c155f3f8144da3e 527 Pfam PF00005 ABC transporter 30 181 2.5E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_21380 74ad83b73fee92691c155f3f8144da3e 527 Gene3D G3DSA:3.40.50.300 258 520 1.5E-40 T 14-10-2018 TSH58p_07610 ff4753acbbc3f0aeb7bc0582c10f3cd8 255 Gene3D G3DSA:3.60.20.10 1 255 3.7E-100 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_07610 ff4753acbbc3f0aeb7bc0582c10f3cd8 255 SUPERFAMILY SSF56235 2 251 5.53E-47 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_07610 ff4753acbbc3f0aeb7bc0582c10f3cd8 255 Pfam PF13230 Glutamine amidotransferases class-II 1 252 1.8E-114 T 14-10-2018 IPR026869 Putative glutamine amidotransferase type 2 TSH58p_11955 cfbdadce48116992704c60644493fad3 562 Gene3D G3DSA:3.40.50.720 146 352 7.1E-39 T 14-10-2018 TSH58p_11955 cfbdadce48116992704c60644493fad3 562 SUPERFAMILY SSF48179 349 442 2.38E-14 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_11955 cfbdadce48116992704c60644493fad3 562 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 147 331 1.2E-23 T 14-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSH58p_11955 cfbdadce48116992704c60644493fad3 562 Gene3D G3DSA:3.40.50.720 381 529 7.0E-24 T 14-10-2018 TSH58p_11955 cfbdadce48116992704c60644493fad3 562 Gene3D G3DSA:1.20.5.100 353 379 1.7E-5 T 14-10-2018 TSH58p_11955 cfbdadce48116992704c60644493fad3 562 SUPERFAMILY SSF51735 147 342 3.63E-30 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_11955 cfbdadce48116992704c60644493fad3 562 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 349 442 1.9E-20 T 14-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSH58p_11955 cfbdadce48116992704c60644493fad3 562 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 147 506 4.6E-63 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 TSH58p_11955 cfbdadce48116992704c60644493fad3 562 SUPERFAMILY SSF52413 463 508 4.32E-7 T 14-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 TSH58p_11955 cfbdadce48116992704c60644493fad3 562 SMART SM00984 462 545 0.0061 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSH58p_28060 104742f244cd12a4cc5909886c5c22f6 333 Pfam PF00753 Metallo-beta-lactamase superfamily 96 290 3.7E-18 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_28060 104742f244cd12a4cc5909886c5c22f6 333 SUPERFAMILY SSF56281 38 324 6.94E-52 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_28060 104742f244cd12a4cc5909886c5c22f6 333 Gene3D G3DSA:3.60.15.10 36 331 6.7E-102 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_28060 104742f244cd12a4cc5909886c5c22f6 333 SMART SM00849 97 303 1.1E-17 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_26305 eb79121f57f76e35aa074d1a30f2cde6 231 Gene3D G3DSA:1.10.10.10 133 231 3.8E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_26305 eb79121f57f76e35aa074d1a30f2cde6 231 SMART SM00448 3 113 5.8E-41 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_26305 eb79121f57f76e35aa074d1a30f2cde6 231 SMART SM00862 153 229 1.4E-23 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_26305 eb79121f57f76e35aa074d1a30f2cde6 231 Gene3D G3DSA:3.40.50.2300 1 130 5.6E-39 T 14-10-2018 TSH58p_26305 eb79121f57f76e35aa074d1a30f2cde6 231 SUPERFAMILY SSF52172 3 174 5.98E-41 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_26305 eb79121f57f76e35aa074d1a30f2cde6 231 Pfam PF00072 Response regulator receiver domain 5 114 3.5E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_26305 eb79121f57f76e35aa074d1a30f2cde6 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 228 3.8E-23 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_10545 61a913ce50e8feff1e96f6dcc52401a9 257 Pfam PF00970 Oxidoreductase FAD-binding domain 19 90 4.2E-6 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 TSH58p_10545 61a913ce50e8feff1e96f6dcc52401a9 257 Gene3D G3DSA:2.40.30.10 1 97 1.7E-29 T 14-10-2018 TSH58p_10545 61a913ce50e8feff1e96f6dcc52401a9 257 Pfam PF00175 Oxidoreductase NAD-binding domain 112 228 2.9E-6 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 TSH58p_10545 61a913ce50e8feff1e96f6dcc52401a9 257 Gene3D G3DSA:3.40.50.80 98 256 1.3E-39 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TSH58p_10545 61a913ce50e8feff1e96f6dcc52401a9 257 SUPERFAMILY SSF52343 103 255 1.83E-37 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TSH58p_10545 61a913ce50e8feff1e96f6dcc52401a9 257 SUPERFAMILY SSF63380 4 99 3.05E-24 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TSH58p_11215 3f67195466a1e0e789ce213b57b4fd14 294 Gene3D G3DSA:1.10.10.10 1 82 5.5E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_11215 3f67195466a1e0e789ce213b57b4fd14 294 Pfam PF03466 LysR substrate binding domain 93 279 7.7E-20 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_11215 3f67195466a1e0e789ce213b57b4fd14 294 SUPERFAMILY SSF53850 85 277 1.07E-23 T 14-10-2018 TSH58p_11215 3f67195466a1e0e789ce213b57b4fd14 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 61 2.4E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_11215 3f67195466a1e0e789ce213b57b4fd14 294 Gene3D G3DSA:3.40.190.290 89 291 7.3E-78 T 14-10-2018 TSH58p_11215 3f67195466a1e0e789ce213b57b4fd14 294 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 2 290 2.2E-113 T 14-10-2018 IPR017685 HTH-type transcriptional regulator ArgP TSH58p_11215 3f67195466a1e0e789ce213b57b4fd14 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 9.4E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_11215 3f67195466a1e0e789ce213b57b4fd14 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 9.4E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_11215 3f67195466a1e0e789ce213b57b4fd14 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 9.4E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_11215 3f67195466a1e0e789ce213b57b4fd14 294 SUPERFAMILY SSF46785 1 111 3.11E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_12035 72204c2ada7d668b8f3c001bd7d0c231 594 Gene3D G3DSA:1.10.287.950 302 588 1.2E-56 T 14-10-2018 TSH58p_12035 72204c2ada7d668b8f3c001bd7d0c231 594 SUPERFAMILY SSF58104 273 587 7.72E-63 T 14-10-2018 TSH58p_12035 72204c2ada7d668b8f3c001bd7d0c231 594 Pfam PF00672 HAMP domain 246 294 2.1E-6 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_12035 72204c2ada7d668b8f3c001bd7d0c231 594 Gene3D G3DSA:1.20.1480.50 206 301 7.3E-12 T 14-10-2018 TSH58p_12035 72204c2ada7d668b8f3c001bd7d0c231 594 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 354 383 1.7E-23 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_12035 72204c2ada7d668b8f3c001bd7d0c231 594 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 42 67 1.7E-23 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_12035 72204c2ada7d668b8f3c001bd7d0c231 594 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 432 459 1.7E-23 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_12035 72204c2ada7d668b8f3c001bd7d0c231 594 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 461 490 1.7E-23 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_12035 72204c2ada7d668b8f3c001bd7d0c231 594 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 509 538 1.7E-23 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_12035 72204c2ada7d668b8f3c001bd7d0c231 594 SMART SM00283 334 588 5.3E-45 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_12035 72204c2ada7d668b8f3c001bd7d0c231 594 SMART SM00304 245 298 5.4E-5 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_12035 72204c2ada7d668b8f3c001bd7d0c231 594 Pfam PF12729 Four helix bundle sensory module for signal transduction 41 218 2.1E-18 T 14-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain TSH58p_12035 72204c2ada7d668b8f3c001bd7d0c231 594 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 398 556 7.9E-30 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_24175 6cc3227f55b46020e7c658b89d06c535 570 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 485 514 3.4E-18 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_24175 6cc3227f55b46020e7c658b89d06c535 570 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 330 359 3.4E-18 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_24175 6cc3227f55b46020e7c658b89d06c535 570 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 408 435 3.4E-18 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_24175 6cc3227f55b46020e7c658b89d06c535 570 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 437 466 3.4E-18 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_24175 6cc3227f55b46020e7c658b89d06c535 570 SMART SM00283 310 564 1.5E-37 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_24175 6cc3227f55b46020e7c658b89d06c535 570 Pfam PF00672 HAMP domain 221 267 4.6E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_24175 6cc3227f55b46020e7c658b89d06c535 570 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 373 534 5.2E-29 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_24175 6cc3227f55b46020e7c658b89d06c535 570 SUPERFAMILY SSF58104 249 563 2.88E-56 T 14-10-2018 TSH58p_24175 6cc3227f55b46020e7c658b89d06c535 570 SMART SM00304 221 274 2.3E-12 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_24175 6cc3227f55b46020e7c658b89d06c535 570 SMART SM00304 491 554 67.0 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_24175 6cc3227f55b46020e7c658b89d06c535 570 Gene3D G3DSA:1.10.287.950 281 564 3.0E-49 T 14-10-2018 TSH58p_24175 6cc3227f55b46020e7c658b89d06c535 570 Gene3D G3DSA:1.20.1480.50 182 280 1.4E-16 T 14-10-2018 TSH58p_09785 78da07dcdae1db078daa866c07ed1695 118 Pfam PF05899 Protein of unknown function (DUF861) 41 113 2.3E-20 T 14-10-2018 IPR008579 Domain of unknown function DUF861, cupin-3 KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 TSH58p_09785 78da07dcdae1db078daa866c07ed1695 118 SUPERFAMILY SSF51182 13 115 1.62E-17 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_09785 78da07dcdae1db078daa866c07ed1695 118 Gene3D G3DSA:2.60.120.10 5 115 4.6E-26 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_14125 897fbe387a66b9faff60b60c285bc380 378 SUPERFAMILY SSF55874 192 358 1.83E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_14125 897fbe387a66b9faff60b60c285bc380 378 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 248 359 2.5E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_14125 897fbe387a66b9faff60b60c285bc380 378 SUPERFAMILY SSF47384 126 200 6.28E-17 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_14125 897fbe387a66b9faff60b60c285bc380 378 Pfam PF00512 His Kinase A (phospho-acceptor) domain 133 201 9.0E-17 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_14125 897fbe387a66b9faff60b60c285bc380 378 PRINTS PR00344 Bacterial sensor protein C-terminal signature 321 339 4.8E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_14125 897fbe387a66b9faff60b60c285bc380 378 PRINTS PR00344 Bacterial sensor protein C-terminal signature 304 314 4.8E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_14125 897fbe387a66b9faff60b60c285bc380 378 PRINTS PR00344 Bacterial sensor protein C-terminal signature 286 300 4.8E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_14125 897fbe387a66b9faff60b60c285bc380 378 PRINTS PR00344 Bacterial sensor protein C-terminal signature 345 358 4.8E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_14125 897fbe387a66b9faff60b60c285bc380 378 SMART SM00388 133 202 1.2E-18 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_14125 897fbe387a66b9faff60b60c285bc380 378 SMART SM00387 248 361 8.4E-33 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_14125 897fbe387a66b9faff60b60c285bc380 378 Gene3D G3DSA:1.10.287.130 120 203 2.1E-20 T 14-10-2018 TSH58p_14125 897fbe387a66b9faff60b60c285bc380 378 Gene3D G3DSA:3.30.565.10 204 361 6.1E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_15100 a550f9312a461539179dda0e98ddc87a 176 Pfam PF02357 Transcription termination factor nusG 4 106 1.1E-28 T 14-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TSH58p_15100 a550f9312a461539179dda0e98ddc87a 176 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 1.9E-20 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 TSH58p_15100 a550f9312a461539179dda0e98ddc87a 176 PRINTS PR00338 Transcription termination factor NUSG signature 134 149 1.9E-20 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 TSH58p_15100 a550f9312a461539179dda0e98ddc87a 176 PRINTS PR00338 Transcription termination factor NUSG signature 152 168 1.9E-20 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 TSH58p_15100 a550f9312a461539179dda0e98ddc87a 176 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 176 6.6E-72 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 TSH58p_15100 a550f9312a461539179dda0e98ddc87a 176 SUPERFAMILY SSF50104 120 176 2.41E-19 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily TSH58p_15100 a550f9312a461539179dda0e98ddc87a 176 Gene3D G3DSA:2.30.30.30 117 176 1.7E-26 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 TSH58p_15100 a550f9312a461539179dda0e98ddc87a 176 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 176 25.932 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 TSH58p_15100 a550f9312a461539179dda0e98ddc87a 176 SMART SM00738 2 110 2.7E-50 T 14-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TSH58p_15100 a550f9312a461539179dda0e98ddc87a 176 SUPERFAMILY SSF82679 4 112 5.89E-41 T 14-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TSH58p_15100 a550f9312a461539179dda0e98ddc87a 176 Gene3D G3DSA:3.30.70.940 1 116 3.9E-46 T 14-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TSH58p_15100 a550f9312a461539179dda0e98ddc87a 176 SMART SM00739 122 149 1.5E-5 T 14-10-2018 IPR005824 KOW TSH58p_15100 a550f9312a461539179dda0e98ddc87a 176 Pfam PF00467 KOW motif 125 155 6.5E-6 T 14-10-2018 IPR005824 KOW TSH58p_15100 a550f9312a461539179dda0e98ddc87a 176 ProSitePatterns PS01014 Transcription termination factor nusG signature. 159 168 - T 14-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site TSH58p_25695 19b4684df7184edf2c235e2949238a6f 540 SUPERFAMILY SSF46977 428 519 1.7E-23 T 14-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_25695 19b4684df7184edf2c235e2949238a6f 540 Gene3D G3DSA:3.50.50.60 12 390 1.8E-130 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_25695 19b4684df7184edf2c235e2949238a6f 540 Gene3D G3DSA:1.20.58.100 411 509 7.8E-20 T 14-10-2018 TSH58p_25695 19b4684df7184edf2c235e2949238a6f 540 SUPERFAMILY SSF56425 228 338 1.33E-30 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_25695 19b4684df7184edf2c235e2949238a6f 540 SUPERFAMILY SSF51905 10 399 1.02E-57 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_25695 19b4684df7184edf2c235e2949238a6f 540 Pfam PF02910 Fumarate reductase flavoprotein C-term 428 512 1.4E-12 T 14-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_25695 19b4684df7184edf2c235e2949238a6f 540 Gene3D G3DSA:3.90.700.10 237 344 1.8E-130 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_25695 19b4684df7184edf2c235e2949238a6f 540 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 341 363 2.0E-9 T 14-10-2018 TSH58p_25695 19b4684df7184edf2c235e2949238a6f 540 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 2.0E-9 T 14-10-2018 TSH58p_25695 19b4684df7184edf2c235e2949238a6f 540 Pfam PF00890 FAD binding domain 12 378 1.3E-75 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_25695 19b4684df7184edf2c235e2949238a6f 540 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 10 508 6.7E-149 T 14-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 TSH58p_26045 445cbda260b90afcc4f44bd27e672343 324 PIRSF PIRSF005261 10 323 2.0E-79 T 14-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 TSH58p_26045 445cbda260b90afcc4f44bd27e672343 324 SUPERFAMILY SSF64397 20 273 1.14E-63 T 14-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 TSH58p_26045 445cbda260b90afcc4f44bd27e672343 324 Gene3D G3DSA:1.10.287.480 215 264 9.7E-10 T 14-10-2018 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain superfamily TSH58p_26045 445cbda260b90afcc4f44bd27e672343 324 Gene3D G3DSA:3.90.1280.10 265 323 2.4E-20 T 14-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 TSH58p_26045 445cbda260b90afcc4f44bd27e672343 324 Pfam PF01430 Hsp33 protein 21 312 2.7E-83 T 14-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 TSH58p_26045 445cbda260b90afcc4f44bd27e672343 324 Gene3D G3DSA:3.55.30.10 17 206 3.5E-63 T 14-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 TSH58p_26045 445cbda260b90afcc4f44bd27e672343 324 SUPERFAMILY SSF118352 265 320 7.06E-18 T 14-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 TSH58p_02830 33bf0b0f5ad1a9372ffce3bbc9d2db7a 315 SUPERFAMILY SSF51735 4 313 2.21E-89 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_02830 33bf0b0f5ad1a9372ffce3bbc9d2db7a 315 Gene3D G3DSA:3.40.50.720 7 297 1.5E-106 T 14-10-2018 TSH58p_02830 33bf0b0f5ad1a9372ffce3bbc9d2db7a 315 Gene3D G3DSA:3.90.25.10 187 310 1.5E-106 T 14-10-2018 TSH58p_02830 33bf0b0f5ad1a9372ffce3bbc9d2db7a 315 Pfam PF16363 GDP-mannose 4,6 dehydratase 9 306 3.4E-54 T 14-10-2018 IPR016040 NAD(P)-binding domain TSH58p_11995 2f62c165247ce60eb809e023599631a5 269 Pfam PF13489 Methyltransferase domain 43 116 3.8E-7 T 14-10-2018 TSH58p_11995 2f62c165247ce60eb809e023599631a5 269 SUPERFAMILY SSF53335 16 186 3.73E-14 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_11995 2f62c165247ce60eb809e023599631a5 269 Gene3D G3DSA:3.40.50.150 14 171 3.4E-13 T 14-10-2018 TSH58p_19350 2d60ba4bde9af57a649b363a91915475 566 Gene3D G3DSA:1.10.540.10 175 293 3.0E-33 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TSH58p_19350 2d60ba4bde9af57a649b363a91915475 566 Gene3D G3DSA:1.20.140.10 420 565 1.1E-43 T 14-10-2018 TSH58p_19350 2d60ba4bde9af57a649b363a91915475 566 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 182 292 4.5E-30 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TSH58p_19350 2d60ba4bde9af57a649b363a91915475 566 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 520 539 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TSH58p_19350 2d60ba4bde9af57a649b363a91915475 566 Gene3D G3DSA:2.40.110.10 296 419 1.9E-30 T 14-10-2018 TSH58p_19350 2d60ba4bde9af57a649b363a91915475 566 SUPERFAMILY SSF56645 180 424 3.01E-68 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TSH58p_19350 2d60ba4bde9af57a649b363a91915475 566 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 299 398 3.5E-16 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TSH58p_19350 2d60ba4bde9af57a649b363a91915475 566 SUPERFAMILY SSF47203 412 563 2.9E-46 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TSH58p_19350 2d60ba4bde9af57a649b363a91915475 566 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 413 561 2.8E-39 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TSH58p_04355 8fd3563e772b5fbbe38050f02c822f72 334 Gene3D G3DSA:3.40.50.1100 38 151 7.4E-117 T 14-10-2018 TSH58p_04355 8fd3563e772b5fbbe38050f02c822f72 334 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 306 4.1E-70 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TSH58p_04355 8fd3563e772b5fbbe38050f02c822f72 334 Gene3D G3DSA:3.40.50.1100 10 312 7.4E-117 T 14-10-2018 TSH58p_04355 8fd3563e772b5fbbe38050f02c822f72 334 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 14-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 TSH58p_04355 8fd3563e772b5fbbe38050f02c822f72 334 SUPERFAMILY SSF53686 6 327 1.1E-95 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TSH58p_25140 e6ece68ec8d6751a5b3ddcada11c8bbc 389 Gene3D G3DSA:3.40.50.10540 4 347 1.1E-111 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily TSH58p_25140 e6ece68ec8d6751a5b3ddcada11c8bbc 389 Pfam PF02515 CoA-transferase family III 5 365 6.1E-106 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 TSH58p_25140 e6ece68ec8d6751a5b3ddcada11c8bbc 389 Gene3D G3DSA:3.30.1540.10 223 316 1.1E-111 T 14-10-2018 TSH58p_25140 e6ece68ec8d6751a5b3ddcada11c8bbc 389 SUPERFAMILY SSF89796 1 372 2.75E-112 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily TSH58p_25925 3c7a9cd22bbe1b2c45361f0b581d0d46 451 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 4 414 22.753 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TSH58p_25925 3c7a9cd22bbe1b2c45361f0b581d0d46 451 Gene3D G3DSA:3.30.460.30 3 159 1.2E-42 T 14-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TSH58p_25925 3c7a9cd22bbe1b2c45361f0b581d0d46 451 PIRSF PIRSF000445 3 422 1.3E-107 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TSH58p_25925 3c7a9cd22bbe1b2c45361f0b581d0d46 451 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 322 405 2.4E-8 T 14-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TSH58p_25925 3c7a9cd22bbe1b2c45361f0b581d0d46 451 SUPERFAMILY SSF51735 162 315 1.55E-23 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_25925 3c7a9cd22bbe1b2c45361f0b581d0d46 451 SUPERFAMILY SSF69742 4 159 3.79E-34 T 14-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TSH58p_25925 3c7a9cd22bbe1b2c45361f0b581d0d46 451 SUPERFAMILY SSF69075 319 396 8.89E-9 T 14-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TSH58p_25925 3c7a9cd22bbe1b2c45361f0b581d0d46 451 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 173 307 3.6E-21 T 14-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase TSH58p_25925 3c7a9cd22bbe1b2c45361f0b581d0d46 451 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 8 157 2.0E-34 T 14-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TSH58p_25925 3c7a9cd22bbe1b2c45361f0b581d0d46 451 Gene3D G3DSA:3.40.50.720 162 312 2.0E-30 T 14-10-2018 TSH58p_25925 3c7a9cd22bbe1b2c45361f0b581d0d46 451 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 5 398 3.5E-84 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TSH58p_22590 a45d16f0535b7b4c6e46d54990b4c811 80 Gene3D G3DSA:1.10.3990.20 1 79 3.2E-19 T 14-10-2018 IPR038268 Ribbon-helix-helix domain superfamily TSH58p_22590 a45d16f0535b7b4c6e46d54990b4c811 80 Pfam PF13467 Ribbon-helix-helix domain 1 61 1.5E-23 T 14-10-2018 IPR027373 Ribbon-helix-helix domain TSH58p_29260 e155f372ad63ff8c8d88fedf7098f290 429 SUPERFAMILY SSF53335 227 412 1.06E-27 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_29260 e155f372ad63ff8c8d88fedf7098f290 429 SMART SM00028 134 167 0.0097 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29260 e155f372ad63ff8c8d88fedf7098f290 429 SMART SM00028 32 65 25.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29260 e155f372ad63ff8c8d88fedf7098f290 429 SMART SM00028 66 99 4.9E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29260 e155f372ad63ff8c8d88fedf7098f290 429 SMART SM00028 100 133 0.6 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29260 e155f372ad63ff8c8d88fedf7098f290 429 Gene3D G3DSA:3.40.50.150 226 406 6.0E-26 T 14-10-2018 TSH58p_29260 e155f372ad63ff8c8d88fedf7098f290 429 SUPERFAMILY SSF48452 40 208 8.63E-28 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29260 e155f372ad63ff8c8d88fedf7098f290 429 Gene3D G3DSA:1.25.40.10 104 143 7.4E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29260 e155f372ad63ff8c8d88fedf7098f290 429 Gene3D G3DSA:1.25.40.10 74 103 7.3E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29260 e155f372ad63ff8c8d88fedf7098f290 429 Gene3D G3DSA:1.25.40.10 144 180 8.6E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29260 e155f372ad63ff8c8d88fedf7098f290 429 Gene3D G3DSA:1.25.40.10 35 73 6.1E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29260 e155f372ad63ff8c8d88fedf7098f290 429 Pfam PF13432 Tetratricopeptide repeat 36 96 3.5E-8 T 14-10-2018 TSH58p_29260 e155f372ad63ff8c8d88fedf7098f290 429 Pfam PF13432 Tetratricopeptide repeat 104 166 0.0036 T 14-10-2018 TSH58p_29260 e155f372ad63ff8c8d88fedf7098f290 429 Pfam PF13489 Methyltransferase domain 253 367 2.0E-12 T 14-10-2018 TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 SMART SM00267 388 561 1.9E-53 T 14-10-2018 IPR000160 GGDEF domain TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 Gene3D G3DSA:3.30.450.20 4 72 4.0E-15 T 14-10-2018 TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 Gene3D G3DSA:3.30.450.20 267 340 2.3E-21 T 14-10-2018 TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 Gene3D G3DSA:3.30.450.20 139 209 2.2E-21 T 14-10-2018 TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 SUPERFAMILY SSF55785 256 386 6.6E-24 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 Pfam PF00563 EAL domain 578 814 3.9E-72 T 14-10-2018 IPR001633 EAL domain TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 268 395 2.5E-15 T 14-10-2018 IPR000014 PAS domain TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 139 266 5.8E-14 T 14-10-2018 IPR000014 PAS domain TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 Gene3D G3DSA:2.10.70.100 77 133 3.5E-8 T 14-10-2018 TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 Gene3D G3DSA:2.10.70.100 344 390 1.9E-9 T 14-10-2018 TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 Gene3D G3DSA:2.10.70.100 213 261 5.5E-14 T 14-10-2018 TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 Pfam PF08447 PAS fold 29 124 1.4E-10 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 Pfam PF08447 PAS fold 166 251 4.0E-20 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 Pfam PF08447 PAS fold 294 381 3.6E-17 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 SUPERFAMILY SSF141868 576 826 6.93E-89 T 14-10-2018 IPR035919 EAL domain superfamily TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 SMART SM00091 6 73 2.0E-4 T 14-10-2018 IPR000014 PAS domain TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 SMART SM00091 143 211 1.8E-4 T 14-10-2018 IPR000014 PAS domain TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 SMART SM00091 271 339 1.4E-4 T 14-10-2018 IPR000014 PAS domain TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 398 561 1.9E-35 T 14-10-2018 IPR000160 GGDEF domain TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 SUPERFAMILY SSF55785 16 133 5.8E-16 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 Pfam PF00990 Diguanylate cyclase, GGDEF domain 399 556 2.5E-42 T 14-10-2018 IPR000160 GGDEF domain TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 SUPERFAMILY SSF55785 128 257 2.42E-25 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 SMART SM00052 571 819 1.3E-115 T 14-10-2018 IPR001633 EAL domain TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 SMART SM00086 217 259 6.2E-8 T 14-10-2018 IPR001610 PAC motif TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 SMART SM00086 346 388 2.5E-7 T 14-10-2018 IPR001610 PAC motif TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 SMART SM00086 80 131 1.0 T 14-10-2018 IPR001610 PAC motif TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 Gene3D G3DSA:3.20.20.450 575 831 7.5E-103 T 14-10-2018 IPR035919 EAL domain superfamily TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 Gene3D G3DSA:3.30.70.270 394 574 7.1E-52 T 14-10-2018 TSH58p_27420 34fb1ea1dc1b273f82f620a09f72e72d 838 SUPERFAMILY SSF55073 404 563 4.47E-42 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_00530 8b4fd59e190eb7f7bfb3236ed5f31aed 456 PRINTS PR00131 Glycosyl hydrolase family 1 signature 294 308 6.0E-20 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSH58p_00530 8b4fd59e190eb7f7bfb3236ed5f31aed 456 PRINTS PR00131 Glycosyl hydrolase family 1 signature 356 364 6.0E-20 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSH58p_00530 8b4fd59e190eb7f7bfb3236ed5f31aed 456 PRINTS PR00131 Glycosyl hydrolase family 1 signature 424 436 6.0E-20 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSH58p_00530 8b4fd59e190eb7f7bfb3236ed5f31aed 456 PRINTS PR00131 Glycosyl hydrolase family 1 signature 379 390 6.0E-20 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSH58p_00530 8b4fd59e190eb7f7bfb3236ed5f31aed 456 PRINTS PR00131 Glycosyl hydrolase family 1 signature 400 417 6.0E-20 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSH58p_00530 8b4fd59e190eb7f7bfb3236ed5f31aed 456 Pfam PF00232 Glycosyl hydrolase family 1 17 450 3.6E-145 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSH58p_00530 8b4fd59e190eb7f7bfb3236ed5f31aed 456 Gene3D G3DSA:3.20.20.80 3 454 4.9E-160 T 14-10-2018 TSH58p_00530 8b4fd59e190eb7f7bfb3236ed5f31aed 456 TIGRFAM TIGR03356 BGL: beta-galactosidase 18 446 7.0E-169 T 14-10-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092|MetaCyc: PWY-7913 TSH58p_00530 8b4fd59e190eb7f7bfb3236ed5f31aed 456 SUPERFAMILY SSF51445 17 451 5.77E-156 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_00530 8b4fd59e190eb7f7bfb3236ed5f31aed 456 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 22 36 - T 14-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site TSH58p_12730 31fa0fc3c1a351e5bd302d2ad925344b 600 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 69 592 9.0E-123 T 14-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 TSH58p_12730 31fa0fc3c1a351e5bd302d2ad925344b 600 Gene3D G3DSA:1.10.246.130 300 419 1.7E-37 T 14-10-2018 TSH58p_12730 31fa0fc3c1a351e5bd302d2ad925344b 600 Pfam PF01019 Gamma-glutamyltranspeptidase 83 595 1.3E-154 T 14-10-2018 TSH58p_12730 31fa0fc3c1a351e5bd302d2ad925344b 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 284 300 5.5E-68 T 14-10-2018 TSH58p_12730 31fa0fc3c1a351e5bd302d2ad925344b 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 503 520 5.5E-68 T 14-10-2018 TSH58p_12730 31fa0fc3c1a351e5bd302d2ad925344b 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 90 115 5.5E-68 T 14-10-2018 TSH58p_12730 31fa0fc3c1a351e5bd302d2ad925344b 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 479 494 5.5E-68 T 14-10-2018 TSH58p_12730 31fa0fc3c1a351e5bd302d2ad925344b 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 314 333 5.5E-68 T 14-10-2018 TSH58p_12730 31fa0fc3c1a351e5bd302d2ad925344b 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 421 439 5.5E-68 T 14-10-2018 TSH58p_12730 31fa0fc3c1a351e5bd302d2ad925344b 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 165 183 5.5E-68 T 14-10-2018 TSH58p_12730 31fa0fc3c1a351e5bd302d2ad925344b 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 183 202 5.5E-68 T 14-10-2018 TSH58p_12730 31fa0fc3c1a351e5bd302d2ad925344b 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 443 461 5.5E-68 T 14-10-2018 TSH58p_12730 31fa0fc3c1a351e5bd302d2ad925344b 600 ProSitePatterns PS00462 Gamma-glutamyltranspeptidase signature. 421 445 - T 14-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 TSH58p_12730 31fa0fc3c1a351e5bd302d2ad925344b 600 SUPERFAMILY SSF56235 61 599 1.1E-168 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_12730 31fa0fc3c1a351e5bd302d2ad925344b 600 Gene3D G3DSA:3.60.20.40 421 600 1.4E-57 T 14-10-2018 TSH58p_06865 1c13b754d20e9e2036697749f822f3f1 335 SUPERFAMILY SSF50129 9 148 2.74E-37 T 14-10-2018 IPR011032 GroES-like superfamily TSH58p_06865 1c13b754d20e9e2036697749f822f3f1 335 Gene3D G3DSA:3.90.180.10 21 330 1.8E-112 T 14-10-2018 TSH58p_06865 1c13b754d20e9e2036697749f822f3f1 335 Gene3D G3DSA:3.40.50.720 128 270 1.8E-112 T 14-10-2018 TSH58p_06865 1c13b754d20e9e2036697749f822f3f1 335 Pfam PF00107 Zinc-binding dehydrogenase 159 274 3.6E-33 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TSH58p_06865 1c13b754d20e9e2036697749f822f3f1 335 SUPERFAMILY SSF51735 120 295 2.39E-55 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_06865 1c13b754d20e9e2036697749f822f3f1 335 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 9 333 9.6E-151 T 14-10-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 TSH58p_06865 1c13b754d20e9e2036697749f822f3f1 335 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 35 107 6.1E-8 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TSH58p_06865 1c13b754d20e9e2036697749f822f3f1 335 SMART SM00829 18 331 3.0E-55 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TSH58p_31670 af07fe69de83e2b5ce481c2e9b44c759 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 4.4E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_31670 af07fe69de83e2b5ce481c2e9b44c759 296 Gene3D G3DSA:1.10.10.10 3 85 6.7E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_31670 af07fe69de83e2b5ce481c2e9b44c759 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 8.4E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_31670 af07fe69de83e2b5ce481c2e9b44c759 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 8.4E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_31670 af07fe69de83e2b5ce481c2e9b44c759 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 8.4E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_31670 af07fe69de83e2b5ce481c2e9b44c759 296 SUPERFAMILY SSF53850 90 292 9.41E-40 T 14-10-2018 TSH58p_31670 af07fe69de83e2b5ce481c2e9b44c759 296 Pfam PF03466 LysR substrate binding domain 89 289 2.1E-37 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_31670 af07fe69de83e2b5ce481c2e9b44c759 296 Gene3D G3DSA:3.40.190.10 92 285 7.1E-56 T 14-10-2018 TSH58p_31670 af07fe69de83e2b5ce481c2e9b44c759 296 SUPERFAMILY SSF46785 3 111 1.28E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_31670 af07fe69de83e2b5ce481c2e9b44c759 296 Gene3D G3DSA:3.40.190.10 163 260 7.1E-56 T 14-10-2018 TSH58p_03220 081ea32dc8c6c672fd83267991d236ee 1136 Pfam PF00501 AMP-binding enzyme 637 1035 3.4E-72 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_03220 081ea32dc8c6c672fd83267991d236ee 1136 Gene3D G3DSA:1.20.1250.20 7 419 8.7E-23 T 14-10-2018 TSH58p_03220 081ea32dc8c6c672fd83267991d236ee 1136 SUPERFAMILY SSF103473 9 417 2.22E-22 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_03220 081ea32dc8c6c672fd83267991d236ee 1136 Gene3D G3DSA:3.40.50.12780 624 1030 6.5E-80 T 14-10-2018 TSH58p_03220 081ea32dc8c6c672fd83267991d236ee 1136 SUPERFAMILY SSF56801 619 1130 1.57E-100 T 14-10-2018 TSH58p_03220 081ea32dc8c6c672fd83267991d236ee 1136 SMART SM00563 453 562 3.9E-22 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TSH58p_03220 081ea32dc8c6c672fd83267991d236ee 1136 ProSitePatterns PS00455 Putative AMP-binding domain signature. 795 806 - T 14-10-2018 IPR020845 AMP-binding, conserved site TSH58p_03220 081ea32dc8c6c672fd83267991d236ee 1136 Gene3D G3DSA:3.30.300.30 1032 1132 2.3E-9 T 14-10-2018 TSH58p_03220 081ea32dc8c6c672fd83267991d236ee 1136 Pfam PF07690 Major Facilitator Superfamily 16 311 3.9E-11 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_03220 081ea32dc8c6c672fd83267991d236ee 1136 Pfam PF01553 Acyltransferase 438 559 5.1E-14 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TSH58p_03220 081ea32dc8c6c672fd83267991d236ee 1136 SUPERFAMILY SSF69593 429 605 1.24E-21 T 14-10-2018 TSH58p_21510 f3a332e1b4711a582cd5f34c5fd6d046 466 SMART SM00448 3 116 1.1E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_21510 f3a332e1b4711a582cd5f34c5fd6d046 466 Pfam PF00158 Sigma-54 interaction domain 142 306 6.8E-54 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 TSH58p_21510 f3a332e1b4711a582cd5f34c5fd6d046 466 Gene3D G3DSA:3.40.50.2300 2 130 4.6E-35 T 14-10-2018 TSH58p_21510 f3a332e1b4711a582cd5f34c5fd6d046 466 SUPERFAMILY SSF52540 141 374 3.82E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_21510 f3a332e1b4711a582cd5f34c5fd6d046 466 Gene3D G3DSA:1.10.8.60 312 387 1.3E-23 T 14-10-2018 TSH58p_21510 f3a332e1b4711a582cd5f34c5fd6d046 466 Gene3D G3DSA:3.40.50.300 131 311 2.3E-53 T 14-10-2018 TSH58p_21510 f3a332e1b4711a582cd5f34c5fd6d046 466 SUPERFAMILY SSF52172 4 186 3.98E-40 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_21510 f3a332e1b4711a582cd5f34c5fd6d046 466 Pfam PF02954 Bacterial regulatory protein, Fis family 413 451 2.9E-9 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_21510 f3a332e1b4711a582cd5f34c5fd6d046 466 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 353 362 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site TSH58p_21510 f3a332e1b4711a582cd5f34c5fd6d046 466 Pfam PF00072 Response regulator receiver domain 5 116 2.8E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_21510 f3a332e1b4711a582cd5f34c5fd6d046 466 Gene3D G3DSA:1.10.10.60 405 456 1.5E-12 T 14-10-2018 TSH58p_21510 f3a332e1b4711a582cd5f34c5fd6d046 466 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 226 241 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 TSH58p_21510 f3a332e1b4711a582cd5f34c5fd6d046 466 SMART SM00382 162 303 1.9E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_21510 f3a332e1b4711a582cd5f34c5fd6d046 466 SUPERFAMILY SSF46689 353 455 7.62E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_29940 f3a332e1b4711a582cd5f34c5fd6d046 466 SMART SM00448 3 116 1.1E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_29940 f3a332e1b4711a582cd5f34c5fd6d046 466 Pfam PF00158 Sigma-54 interaction domain 142 306 6.8E-54 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 TSH58p_29940 f3a332e1b4711a582cd5f34c5fd6d046 466 Gene3D G3DSA:3.40.50.2300 2 130 4.6E-35 T 14-10-2018 TSH58p_29940 f3a332e1b4711a582cd5f34c5fd6d046 466 SUPERFAMILY SSF52540 141 374 3.82E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_29940 f3a332e1b4711a582cd5f34c5fd6d046 466 Gene3D G3DSA:1.10.8.60 312 387 1.3E-23 T 14-10-2018 TSH58p_29940 f3a332e1b4711a582cd5f34c5fd6d046 466 Gene3D G3DSA:3.40.50.300 131 311 2.3E-53 T 14-10-2018 TSH58p_29940 f3a332e1b4711a582cd5f34c5fd6d046 466 SUPERFAMILY SSF52172 4 186 3.98E-40 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_29940 f3a332e1b4711a582cd5f34c5fd6d046 466 Pfam PF02954 Bacterial regulatory protein, Fis family 413 451 2.9E-9 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_29940 f3a332e1b4711a582cd5f34c5fd6d046 466 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 353 362 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site TSH58p_29940 f3a332e1b4711a582cd5f34c5fd6d046 466 Pfam PF00072 Response regulator receiver domain 5 116 2.8E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_29940 f3a332e1b4711a582cd5f34c5fd6d046 466 Gene3D G3DSA:1.10.10.60 405 456 1.5E-12 T 14-10-2018 TSH58p_29940 f3a332e1b4711a582cd5f34c5fd6d046 466 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 226 241 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 TSH58p_29940 f3a332e1b4711a582cd5f34c5fd6d046 466 SMART SM00382 162 303 1.9E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_29940 f3a332e1b4711a582cd5f34c5fd6d046 466 SUPERFAMILY SSF46689 353 455 7.62E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_11090 7754db7dd1fea17b4c25bebc6356a1ab 418 SMART SM00382 170 349 8.8E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_11090 7754db7dd1fea17b4c25bebc6356a1ab 418 Gene3D G3DSA:2.40.50.140 47 123 1.4E-34 T 14-10-2018 TSH58p_11090 7754db7dd1fea17b4c25bebc6356a1ab 418 SMART SM00959 5 47 3.1E-17 T 14-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 TSH58p_11090 7754db7dd1fea17b4c25bebc6356a1ab 418 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 3.0E-32 T 14-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 TSH58p_11090 7754db7dd1fea17b4c25bebc6356a1ab 418 SUPERFAMILY SSF52540 90 371 1.77E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_11090 7754db7dd1fea17b4c25bebc6356a1ab 418 Pfam PF07498 Rho termination factor, N-terminal domain 5 46 2.3E-16 T 14-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 TSH58p_11090 7754db7dd1fea17b4c25bebc6356a1ab 418 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 418 5.9E-214 T 14-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 TSH58p_11090 7754db7dd1fea17b4c25bebc6356a1ab 418 Gene3D G3DSA:3.40.50.300 130 417 1.1E-127 T 14-10-2018 TSH58p_11090 7754db7dd1fea17b4c25bebc6356a1ab 418 SUPERFAMILY SSF68912 1 45 1.02E-11 T 14-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily TSH58p_11090 7754db7dd1fea17b4c25bebc6356a1ab 418 SUPERFAMILY SSF50249 49 125 1.03E-29 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_11090 7754db7dd1fea17b4c25bebc6356a1ab 418 SMART SM00357 52 118 1.4E-17 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 TSH58p_11090 7754db7dd1fea17b4c25bebc6356a1ab 418 Gene3D G3DSA:1.10.720.10 1 45 2.8E-16 T 14-10-2018 TSH58p_11090 7754db7dd1fea17b4c25bebc6356a1ab 418 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 160 363 1.5E-23 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSH58p_11090 7754db7dd1fea17b4c25bebc6356a1ab 418 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 418 250.1 T 14-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 TSH58p_30785 5f93c49e5d9cf103c9467f18e26321e7 397 SUPERFAMILY SSF51604 101 368 1.14E-79 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TSH58p_30785 5f93c49e5d9cf103c9467f18e26321e7 397 Gene3D G3DSA:3.30.390.10 9 368 3.2E-115 T 14-10-2018 IPR029017 Enolase-like, N-terminal TSH58p_30785 5f93c49e5d9cf103c9467f18e26321e7 397 Pfam PF13378 Enolase C-terminal domain-like 140 359 2.7E-60 T 14-10-2018 IPR029065 Enolase C-terminal domain-like TSH58p_30785 5f93c49e5d9cf103c9467f18e26321e7 397 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 18 113 5.0E-18 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain TSH58p_30785 5f93c49e5d9cf103c9467f18e26321e7 397 Gene3D G3DSA:3.20.20.120 108 350 3.2E-115 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TSH58p_30785 5f93c49e5d9cf103c9467f18e26321e7 397 SMART SM00922 134 240 1.1E-26 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal TSH58p_30785 5f93c49e5d9cf103c9467f18e26321e7 397 SUPERFAMILY SSF54826 1 118 2.92E-27 T 14-10-2018 TSH58p_13635 85424935bf56e876c9ddbfb367a275fa 750 TIGRFAM TIGR00595 priA: primosomal protein N' 242 747 2.8E-196 T 14-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 TSH58p_13635 85424935bf56e876c9ddbfb367a275fa 750 SMART SM00490 520 613 1.2E-4 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_13635 85424935bf56e876c9ddbfb367a275fa 750 Gene3D G3DSA:3.40.50.300 210 399 2.7E-67 T 14-10-2018 TSH58p_13635 85424935bf56e876c9ddbfb367a275fa 750 Pfam PF00270 DEAD/DEAH box helicase 240 381 7.7E-15 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TSH58p_13635 85424935bf56e876c9ddbfb367a275fa 750 SUPERFAMILY SSF52540 241 638 3.01E-28 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_13635 85424935bf56e876c9ddbfb367a275fa 750 Gene3D G3DSA:1.10.8.630 31 137 2.8E-22 T 14-10-2018 TSH58p_13635 85424935bf56e876c9ddbfb367a275fa 750 SUPERFAMILY SSF52540 215 392 1.25E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_13635 85424935bf56e876c9ddbfb367a275fa 750 SMART SM00487 214 413 1.7E-26 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSH58p_13635 85424935bf56e876c9ddbfb367a275fa 750 Hamap MF_00983 Probable primosomal protein N' [priA]. 34 749 23.814 T 14-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 TSH58p_13635 85424935bf56e876c9ddbfb367a275fa 750 Pfam PF00271 Helicase conserved C-terminal domain 545 612 2.2E-4 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_27145 2aa99a68b6103c53faba41361149ef60 291 SUPERFAMILY SSF46785 7 116 1.24E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_27145 2aa99a68b6103c53faba41361149ef60 291 Gene3D G3DSA:3.40.190.10 100 265 1.6E-57 T 14-10-2018 TSH58p_27145 2aa99a68b6103c53faba41361149ef60 291 SUPERFAMILY SSF53850 96 286 1.14E-24 T 14-10-2018 TSH58p_27145 2aa99a68b6103c53faba41361149ef60 291 Pfam PF03466 LysR substrate binding domain 95 264 5.8E-28 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_27145 2aa99a68b6103c53faba41361149ef60 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 9.4E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_27145 2aa99a68b6103c53faba41361149ef60 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 9.4E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_27145 2aa99a68b6103c53faba41361149ef60 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 9.4E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_27145 2aa99a68b6103c53faba41361149ef60 291 Gene3D G3DSA:1.10.10.10 5 89 6.8E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_27145 2aa99a68b6103c53faba41361149ef60 291 Gene3D G3DSA:3.40.190.10 166 259 1.6E-57 T 14-10-2018 TSH58p_27145 2aa99a68b6103c53faba41361149ef60 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 3.6E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_10180 84768d11c2e1a39d181963c1fbccb5cf 606 SMART SM00028 183 216 32.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_10180 84768d11c2e1a39d181963c1fbccb5cf 606 SMART SM00028 106 144 18.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_10180 84768d11c2e1a39d181963c1fbccb5cf 606 SMART SM00028 72 105 390.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_10180 84768d11c2e1a39d181963c1fbccb5cf 606 SMART SM00028 38 71 8.5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_10180 84768d11c2e1a39d181963c1fbccb5cf 606 Gene3D G3DSA:1.25.40.10 166 362 4.7E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_10180 84768d11c2e1a39d181963c1fbccb5cf 606 Gene3D G3DSA:1.25.40.10 6 158 7.4E-23 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_10180 84768d11c2e1a39d181963c1fbccb5cf 606 SUPERFAMILY SSF48452 4 229 1.71E-23 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_18395 022aa117d413067a336fed8a6bfbec8a 452 Gene3D G3DSA:1.10.287.470 111 199 1.0E-7 T 14-10-2018 TSH58p_18395 022aa117d413067a336fed8a6bfbec8a 452 Gene3D G3DSA:2.40.30.170 65 75 1.0E-7 T 14-10-2018 TSH58p_18395 022aa117d413067a336fed8a6bfbec8a 452 Pfam PF13437 HlyD family secretion protein 299 403 1.9E-9 T 14-10-2018 TSH58p_18395 022aa117d413067a336fed8a6bfbec8a 452 Gene3D G3DSA:2.40.50.100 76 110 1.0E-7 T 14-10-2018 TSH58p_18395 022aa117d413067a336fed8a6bfbec8a 452 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 47 70 5.5E-23 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_18395 022aa117d413067a336fed8a6bfbec8a 452 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 89 109 5.5E-23 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_18395 022aa117d413067a336fed8a6bfbec8a 452 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 431 451 5.5E-23 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_18395 022aa117d413067a336fed8a6bfbec8a 452 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 416 431 5.5E-23 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_18395 022aa117d413067a336fed8a6bfbec8a 452 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 311 332 5.5E-23 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_18395 022aa117d413067a336fed8a6bfbec8a 452 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 344 368 5.5E-23 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_18395 022aa117d413067a336fed8a6bfbec8a 452 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 39 451 4.5E-96 T 14-10-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 TSH58p_18395 022aa117d413067a336fed8a6bfbec8a 452 Gene3D G3DSA:2.40.30.170 314 434 3.6E-9 T 14-10-2018 TSH58p_18395 022aa117d413067a336fed8a6bfbec8a 452 Pfam PF13533 Biotin-lipoyl like 89 125 7.1E-6 T 14-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain TSH58p_23360 e441714cad6f3a6e6e1d40d1e1e33425 489 TIGRFAM TIGR03355 VI_chp_2: type VI secretion protein, EvpB/VC_A0108 family 13 485 5.8E-211 T 14-10-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath TSH58p_23360 e441714cad6f3a6e6e1d40d1e1e33425 489 Pfam PF05943 Type VI secretion protein, EvpB/VC_A0108, tail sheath 64 485 7.6E-194 T 14-10-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath TSH58p_30845 4027d49c00758d212b33e0b3e4deb02b 277 Gene3D G3DSA:1.10.3720.10 43 275 1.2E-46 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_30845 4027d49c00758d212b33e0b3e4deb02b 277 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 54 125 1.0E-15 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 TSH58p_30845 4027d49c00758d212b33e0b3e4deb02b 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 272 6.8E-16 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_30845 4027d49c00758d212b33e0b3e4deb02b 277 SUPERFAMILY SSF161098 54 260 4.97E-39 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_02625 370ca2c0c72cf85fe9aa9e6fa539896a 164 Gene3D G3DSA:1.10.1130.10 68 135 7.2E-29 T 14-10-2018 TSH58p_02625 370ca2c0c72cf85fe9aa9e6fa539896a 164 SUPERFAMILY SSF48695 37 155 8.68E-43 T 14-10-2018 IPR036280 Multiheme cytochrome superfamily TSH58p_02625 370ca2c0c72cf85fe9aa9e6fa539896a 164 Pfam PF03892 Nitrate reductase cytochrome c-type subunit (NapB) 38 149 1.4E-46 T 14-10-2018 IPR005591 Nitrate reductase cytochrome c-type subunit NapB TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 PRINTS PR00344 Bacterial sensor protein C-terminal signature 715 725 6.4E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 PRINTS PR00344 Bacterial sensor protein C-terminal signature 697 711 6.4E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 PRINTS PR00344 Bacterial sensor protein C-terminal signature 733 751 6.4E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 PRINTS PR00344 Bacterial sensor protein C-terminal signature 757 770 6.4E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 SUPERFAMILY SSF52172 794 911 9.39E-22 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 SMART SM00387 649 773 1.6E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 SUPERFAMILY SSF55785 233 349 4.54E-8 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 Pfam PF00512 His Kinase A (phospho-acceptor) domain 540 605 8.9E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 SMART SM00388 540 605 1.6E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 SUPERFAMILY SSF55785 348 479 3.84E-24 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 Gene3D G3DSA:3.30.450.20 237 305 3.1E-6 T 14-10-2018 TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 SMART SM00091 246 314 3.5 T 14-10-2018 IPR000014 PAS domain TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 SMART SM00091 363 429 6.0E-5 T 14-10-2018 IPR000014 PAS domain TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 SMART SM00091 113 174 47.0 T 14-10-2018 IPR000014 PAS domain TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 650 771 8.2E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 Gene3D G3DSA:3.30.450.20 322 364 1.0E-5 T 14-10-2018 TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 Pfam PF08448 PAS fold 370 482 1.1E-16 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 Pfam PF00072 Response regulator receiver domain 797 906 1.1E-13 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 SUPERFAMILY SSF55785 103 227 1.74E-9 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 SUPERFAMILY SSF47384 525 605 2.55E-12 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 SUPERFAMILY SSF55874 596 771 5.11E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 SMART SM00448 795 907 1.7E-14 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 Gene3D G3DSA:3.40.50.2300 786 912 6.2E-20 T 14-10-2018 TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 Gene3D G3DSA:3.30.450.20 365 497 4.2E-22 T 14-10-2018 TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 Gene3D G3DSA:1.10.287.130 503 603 3.0E-13 T 14-10-2018 TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 Gene3D G3DSA:3.30.565.10 614 775 6.4E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 Pfam PF12860 PAS fold 252 356 7.4E-24 T 14-10-2018 TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 Pfam PF12860 PAS fold 119 233 5.0E-19 T 14-10-2018 TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 Gene3D G3DSA:3.30.450.20 100 236 6.7E-10 T 14-10-2018 TSH58p_08850 97b0967ab04300bfd961122538a1c5ab 912 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 359 488 1.4E-10 T 14-10-2018 IPR000014 PAS domain TSH58p_30840 5c0392d695fa62bcec1f0070f9c803be 280 Gene3D G3DSA:3.40.190.10 31 253 1.9E-52 T 14-10-2018 TSH58p_30840 5c0392d695fa62bcec1f0070f9c803be 280 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 34 260 9.0E-47 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_30840 5c0392d695fa62bcec1f0070f9c803be 280 SMART SM00062 33 263 1.5E-30 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_30840 5c0392d695fa62bcec1f0070f9c803be 280 SUPERFAMILY SSF53850 23 260 6.29E-49 T 14-10-2018 TSH58p_30840 5c0392d695fa62bcec1f0070f9c803be 280 Gene3D G3DSA:3.40.190.10 120 223 1.9E-52 T 14-10-2018 TSH58p_27720 fa2c3d4f13b9a40d492a00350b55ade5 337 PIRSF PIRSF026760 3 336 3.0E-96 T 14-10-2018 IPR011669 Uncharacterised conserved protein UCP026760 TSH58p_27720 fa2c3d4f13b9a40d492a00350b55ade5 337 Pfam PF17396 Domain of unknown function (DUF1611_N) Rossmann-like domain 39 124 3.5E-27 T 14-10-2018 IPR035402 Domain of unknown function DUF1611-N, Rossmann-like domain TSH58p_27720 fa2c3d4f13b9a40d492a00350b55ade5 337 Gene3D G3DSA:3.40.50.720 3 126 1.3E-21 T 14-10-2018 TSH58p_27720 fa2c3d4f13b9a40d492a00350b55ade5 337 SUPERFAMILY SSF52540 2 332 1.38E-108 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_27720 fa2c3d4f13b9a40d492a00350b55ade5 337 Gene3D G3DSA:3.40.50.300 127 333 1.2E-70 T 14-10-2018 TSH58p_27720 fa2c3d4f13b9a40d492a00350b55ade5 337 Pfam PF07755 Domain of unknown function (DUF1611_C) P-loop domain 130 327 1.4E-70 T 14-10-2018 IPR035086 Domain of unknown function DUF1611, P-loop TSH58p_04130 2d684a250879734b66aa8b2888615212 240 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_04130 2d684a250879734b66aa8b2888615212 240 Gene3D G3DSA:3.40.50.300 7 240 1.3E-52 T 14-10-2018 TSH58p_04130 2d684a250879734b66aa8b2888615212 240 SMART SM00382 36 217 4.6E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_04130 2d684a250879734b66aa8b2888615212 240 Pfam PF00005 ABC transporter 27 168 8.1E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_04130 2d684a250879734b66aa8b2888615212 240 SUPERFAMILY SSF52540 11 237 2.83E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_14245 3065a7d098085ef4e9d600b6f429e00f 556 Pfam PF02463 RecF/RecN/SMC N terminal domain 16 509 4.6E-14 T 14-10-2018 IPR003395 RecF/RecN/SMC, N-terminal TSH58p_14245 3065a7d098085ef4e9d600b6f429e00f 556 SUPERFAMILY SSF52540 3 499 1.86E-24 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_14245 3065a7d098085ef4e9d600b6f429e00f 556 SUPERFAMILY SSF52540 1 217 3.54E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_14245 3065a7d098085ef4e9d600b6f429e00f 556 PIRSF PIRSF003128 1 555 3.4E-154 T 14-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 TSH58p_14245 3065a7d098085ef4e9d600b6f429e00f 556 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 552 5.6E-142 T 14-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 TSH58p_14245 3065a7d098085ef4e9d600b6f429e00f 556 Gene3D G3DSA:3.40.50.300 275 554 2.9E-51 T 14-10-2018 TSH58p_14245 3065a7d098085ef4e9d600b6f429e00f 556 Gene3D G3DSA:3.40.50.300 1 274 2.6E-44 T 14-10-2018 TSH58p_24830 dad264e42562059c0559ea421e9161b8 230 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 35 196 6.4E-43 T 14-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 TSH58p_24830 dad264e42562059c0559ea421e9161b8 230 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 33 198 6.8E-22 T 14-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 TSH58p_05500 709d9792d4a2eb7fb019607026016fec 508 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 140 156 - T 14-10-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 TSH58p_05500 709d9792d4a2eb7fb019607026016fec 508 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 6 502 7.3E-204 T 14-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 TSH58p_05500 709d9792d4a2eb7fb019607026016fec 508 Pfam PF00221 Aromatic amino acid lyase 12 471 8.8E-185 T 14-10-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 TSH58p_05500 709d9792d4a2eb7fb019607026016fec 508 SUPERFAMILY SSF48557 1 500 5.18E-190 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 TSH58p_05500 709d9792d4a2eb7fb019607026016fec 508 Gene3D G3DSA:1.20.200.10 199 506 1.1E-118 T 14-10-2018 TSH58p_05500 709d9792d4a2eb7fb019607026016fec 508 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 4 505 44.116 T 14-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 TSH58p_05500 709d9792d4a2eb7fb019607026016fec 508 Gene3D G3DSA:1.10.275.10 3 198 2.7E-65 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal TSH58p_00280 b7774974114f3eeb400bbefe771285f7 357 Gene3D G3DSA:3.40.190.10 150 282 6.9E-66 T 14-10-2018 TSH58p_00280 b7774974114f3eeb400bbefe771285f7 357 PIRSF PIRSF017082 19 357 1.2E-99 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 TSH58p_00280 b7774974114f3eeb400bbefe771285f7 357 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 73 353 2.4E-25 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 TSH58p_00280 b7774974114f3eeb400bbefe771285f7 357 Gene3D G3DSA:3.40.190.150 53 343 6.9E-66 T 14-10-2018 TSH58p_29180 4b7ed7d1d690c6a6a4e2841a88e1468f 648 SUPERFAMILY SSF53756 389 627 1.13E-24 T 14-10-2018 TSH58p_29180 4b7ed7d1d690c6a6a4e2841a88e1468f 648 SUPERFAMILY SSF48452 126 347 2.11E-30 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29180 4b7ed7d1d690c6a6a4e2841a88e1468f 648 Gene3D G3DSA:1.25.40.10 111 204 6.3E-16 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29180 4b7ed7d1d690c6a6a4e2841a88e1468f 648 Gene3D G3DSA:1.25.40.10 7 110 3.1E-18 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29180 4b7ed7d1d690c6a6a4e2841a88e1468f 648 SUPERFAMILY SSF48452 8 178 6.32E-26 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29180 4b7ed7d1d690c6a6a4e2841a88e1468f 648 Gene3D G3DSA:3.40.50.2000 515 638 3.3E-7 T 14-10-2018 TSH58p_29180 4b7ed7d1d690c6a6a4e2841a88e1468f 648 Pfam PF13432 Tetratricopeptide repeat 77 131 0.014 T 14-10-2018 TSH58p_29180 4b7ed7d1d690c6a6a4e2841a88e1468f 648 Pfam PF13432 Tetratricopeptide repeat 8 71 7.2E-6 T 14-10-2018 TSH58p_29180 4b7ed7d1d690c6a6a4e2841a88e1468f 648 Pfam PF13432 Tetratricopeptide repeat 146 196 1.5E-4 T 14-10-2018 TSH58p_29180 4b7ed7d1d690c6a6a4e2841a88e1468f 648 Pfam PF13432 Tetratricopeptide repeat 309 357 0.015 T 14-10-2018 TSH58p_29180 4b7ed7d1d690c6a6a4e2841a88e1468f 648 Gene3D G3DSA:1.25.40.10 205 284 9.3E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29180 4b7ed7d1d690c6a6a4e2841a88e1468f 648 Gene3D G3DSA:1.25.40.10 285 376 1.2E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29180 4b7ed7d1d690c6a6a4e2841a88e1468f 648 SMART SM00028 72 105 0.2 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29180 4b7ed7d1d690c6a6a4e2841a88e1468f 648 SMART SM00028 207 240 0.011 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29180 4b7ed7d1d690c6a6a4e2841a88e1468f 648 SMART SM00028 174 206 330.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29180 4b7ed7d1d690c6a6a4e2841a88e1468f 648 SMART SM00028 140 173 9.9 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29180 4b7ed7d1d690c6a6a4e2841a88e1468f 648 SMART SM00028 38 71 57.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29180 4b7ed7d1d690c6a6a4e2841a88e1468f 648 SMART SM00028 303 336 75.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_28360 1bce8a7119e42846025e2f0226cf370d 360 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 11 340 1.7E-136 T 14-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSH58p_28360 1bce8a7119e42846025e2f0226cf370d 360 SUPERFAMILY SSF56042 176 345 1.94E-61 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSH58p_28360 1bce8a7119e42846025e2f0226cf370d 360 Pfam PF02769 AIR synthase related protein, C-terminal domain 180 349 9.1E-38 T 14-10-2018 IPR010918 PurM-like, C-terminal domain TSH58p_28360 1bce8a7119e42846025e2f0226cf370d 360 Gene3D G3DSA:3.30.1330.10 9 173 7.8E-68 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSH58p_28360 1bce8a7119e42846025e2f0226cf370d 360 Gene3D G3DSA:3.90.650.10 176 359 3.0E-72 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSH58p_28360 1bce8a7119e42846025e2f0226cf370d 360 Pfam PF00586 AIR synthase related protein, N-terminal domain 57 166 2.8E-15 T 14-10-2018 IPR016188 PurM-like, N-terminal domain TSH58p_28360 1bce8a7119e42846025e2f0226cf370d 360 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 10 354 45.311 T 14-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSH58p_28360 1bce8a7119e42846025e2f0226cf370d 360 SUPERFAMILY SSF55326 11 172 3.89E-49 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSH58p_08210 0e88fecdefb55125685d861fb01dee92 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 258 7.0E-61 T 14-10-2018 TSH58p_08210 0e88fecdefb55125685d861fb01dee92 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 2.4E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_08210 0e88fecdefb55125685d861fb01dee92 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 2.4E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_08210 0e88fecdefb55125685d861fb01dee92 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 2.4E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_08210 0e88fecdefb55125685d861fb01dee92 261 Gene3D G3DSA:3.40.50.720 6 261 5.7E-84 T 14-10-2018 TSH58p_08210 0e88fecdefb55125685d861fb01dee92 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_08210 0e88fecdefb55125685d861fb01dee92 261 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 172 7.4E-4 T 14-10-2018 TSH58p_08210 0e88fecdefb55125685d861fb01dee92 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 3.2E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_08210 0e88fecdefb55125685d861fb01dee92 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 3.2E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_08210 0e88fecdefb55125685d861fb01dee92 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 3.2E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_08210 0e88fecdefb55125685d861fb01dee92 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.2E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_08210 0e88fecdefb55125685d861fb01dee92 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 3.2E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_08210 0e88fecdefb55125685d861fb01dee92 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 3.2E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_08210 0e88fecdefb55125685d861fb01dee92 261 SUPERFAMILY SSF51735 5 259 1.52E-79 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_11165 a2dab9630b52275fe1963df7920e5d3e 449 SMART SM00382 62 338 1.4E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_11165 a2dab9630b52275fe1963df7920e5d3e 449 SMART SM01086 341 435 2.7E-25 T 14-10-2018 IPR019489 Clp ATPase, C-terminal TSH58p_11165 a2dab9630b52275fe1963df7920e5d3e 449 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 18 449 1.5E-186 T 14-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 TSH58p_11165 a2dab9630b52275fe1963df7920e5d3e 449 Gene3D G3DSA:1.10.8.60 341 446 7.9E-40 T 14-10-2018 TSH58p_11165 a2dab9630b52275fe1963df7920e5d3e 449 SUPERFAMILY SSF52540 19 445 2.99E-87 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_11165 a2dab9630b52275fe1963df7920e5d3e 449 Pfam PF07724 AAA domain (Cdc48 subfamily) 204 335 2.7E-38 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSH58p_11165 a2dab9630b52275fe1963df7920e5d3e 449 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 341 411 1.3E-7 T 14-10-2018 IPR019489 Clp ATPase, C-terminal TSH58p_11165 a2dab9630b52275fe1963df7920e5d3e 449 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 14 449 42.119 T 14-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 TSH58p_11165 a2dab9630b52275fe1963df7920e5d3e 449 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 66 116 1.7E-6 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSH58p_03795 333ef4c00f237cf95e15ab61740e4129 185 Gene3D G3DSA:3.40.50.720 1 106 6.1E-16 T 14-10-2018 TSH58p_03795 333ef4c00f237cf95e15ab61740e4129 185 Pfam PF13241 Putative NAD(P)-binding 5 110 2.0E-15 T 14-10-2018 TSH58p_03795 333ef4c00f237cf95e15ab61740e4129 185 SUPERFAMILY SSF51735 2 107 5.25E-8 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_03795 333ef4c00f237cf95e15ab61740e4129 185 Gene3D G3DSA:3.30.160.110 108 143 3.0E-13 T 14-10-2018 TSH58p_03795 333ef4c00f237cf95e15ab61740e4129 185 SUPERFAMILY SSF75615 103 165 4.71E-14 T 14-10-2018 TSH58p_03795 333ef4c00f237cf95e15ab61740e4129 185 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 9 162 1.4E-24 T 14-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TSH58p_03795 333ef4c00f237cf95e15ab61740e4129 185 Pfam PF14824 Sirohaem biosynthesis protein central 114 139 5.4E-8 T 14-10-2018 IPR028281 Siroheme synthase, central domain KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TSH58p_19800 de6fc8e6fac0c95f32343a4d69affdf5 880 SMART SM00448 762 876 1.3E-16 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_19800 de6fc8e6fac0c95f32343a4d69affdf5 880 SMART SM00387 632 743 2.2E-30 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_19800 de6fc8e6fac0c95f32343a4d69affdf5 880 Gene3D G3DSA:1.10.287.130 484 586 6.0E-15 T 14-10-2018 TSH58p_19800 de6fc8e6fac0c95f32343a4d69affdf5 880 SUPERFAMILY SSF52172 764 879 2.42E-21 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_19800 de6fc8e6fac0c95f32343a4d69affdf5 880 SUPERFAMILY SSF55785 377 489 1.18E-30 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_19800 de6fc8e6fac0c95f32343a4d69affdf5 880 SUPERFAMILY SSF55874 578 741 1.31E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_19800 de6fc8e6fac0c95f32343a4d69affdf5 880 Pfam PF00989 PAS fold 367 479 8.0E-18 T 14-10-2018 IPR013767 PAS fold GO:0006355 TSH58p_19800 de6fc8e6fac0c95f32343a4d69affdf5 880 Gene3D G3DSA:3.30.450.20 362 483 2.9E-40 T 14-10-2018 TSH58p_19800 de6fc8e6fac0c95f32343a4d69affdf5 880 Gene3D G3DSA:3.30.450.20 41 183 8.9E-12 T 14-10-2018 TSH58p_19800 de6fc8e6fac0c95f32343a4d69affdf5 880 Gene3D G3DSA:3.40.50.2300 754 880 2.6E-19 T 14-10-2018 TSH58p_19800 de6fc8e6fac0c95f32343a4d69affdf5 880 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 364 489 1.1E-37 T 14-10-2018 IPR000014 PAS domain TSH58p_19800 de6fc8e6fac0c95f32343a4d69affdf5 880 SMART SM00388 523 588 8.6E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_19800 de6fc8e6fac0c95f32343a4d69affdf5 880 PRINTS PR00344 Bacterial sensor protein C-terminal signature 686 696 4.7E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_19800 de6fc8e6fac0c95f32343a4d69affdf5 880 PRINTS PR00344 Bacterial sensor protein C-terminal signature 668 682 4.7E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_19800 de6fc8e6fac0c95f32343a4d69affdf5 880 PRINTS PR00344 Bacterial sensor protein C-terminal signature 727 740 4.7E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_19800 de6fc8e6fac0c95f32343a4d69affdf5 880 PRINTS PR00344 Bacterial sensor protein C-terminal signature 703 721 4.7E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_19800 de6fc8e6fac0c95f32343a4d69affdf5 880 Pfam PF00072 Response regulator receiver domain 764 876 2.2E-11 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_19800 de6fc8e6fac0c95f32343a4d69affdf5 880 SMART SM00091 366 432 6.1E-13 T 14-10-2018 IPR000014 PAS domain TSH58p_19800 de6fc8e6fac0c95f32343a4d69affdf5 880 Pfam PF00512 His Kinase A (phospho-acceptor) domain 523 588 6.1E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_19800 de6fc8e6fac0c95f32343a4d69affdf5 880 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 633 740 6.3E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_19800 de6fc8e6fac0c95f32343a4d69affdf5 880 SUPERFAMILY SSF47384 509 588 8.63E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_19800 de6fc8e6fac0c95f32343a4d69affdf5 880 Gene3D G3DSA:3.30.565.10 598 746 2.6E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_04995 581cac5ee0532735ce4a101fdc3b6e6a 569 ProSitePatterns PS00145 Urease active site. 319 335 - T 14-10-2018 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 TSH58p_04995 581cac5ee0532735ce4a101fdc3b6e6a 569 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 429 442 3.5E-34 T 14-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 TSH58p_04995 581cac5ee0532735ce4a101fdc3b6e6a 569 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 403 418 3.5E-34 T 14-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 TSH58p_04995 581cac5ee0532735ce4a101fdc3b6e6a 569 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 297 314 3.5E-34 T 14-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 TSH58p_04995 581cac5ee0532735ce4a101fdc3b6e6a 569 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 336 352 3.5E-34 T 14-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 TSH58p_04995 581cac5ee0532735ce4a101fdc3b6e6a 569 Gene3D G3DSA:2.30.40.10 5 482 1.1E-300 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_04995 581cac5ee0532735ce4a101fdc3b6e6a 569 SUPERFAMILY SSF51338 427 479 1.34E-5 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_04995 581cac5ee0532735ce4a101fdc3b6e6a 569 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 4 569 4.4E-300 T 14-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 TSH58p_04995 581cac5ee0532735ce4a101fdc3b6e6a 569 Gene3D G3DSA:3.20.20.140 131 569 1.1E-300 T 14-10-2018 TSH58p_04995 581cac5ee0532735ce4a101fdc3b6e6a 569 Hamap MF_01953 Urease subunit alpha [ureC]. 3 569 57.718 T 14-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 TSH58p_04995 581cac5ee0532735ce4a101fdc3b6e6a 569 Pfam PF01979 Amidohydrolase family 127 455 4.5E-83 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TSH58p_04995 581cac5ee0532735ce4a101fdc3b6e6a 569 SUPERFAMILY SSF51338 4 179 1.61E-61 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_04995 581cac5ee0532735ce4a101fdc3b6e6a 569 SUPERFAMILY SSF51556 131 569 2.92E-203 T 14-10-2018 IPR032466 Metal-dependent hydrolase TSH58p_04995 581cac5ee0532735ce4a101fdc3b6e6a 569 ProSitePatterns PS01120 Urease nickel ligands signature. 129 142 - T 14-10-2018 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 TSH58p_04995 581cac5ee0532735ce4a101fdc3b6e6a 569 Pfam PF00449 Urease alpha-subunit, N-terminal domain 4 121 3.5E-55 T 14-10-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 TSH58p_15810 a99e5a9ff33eb4bfb354b73c82badbb0 518 Pfam PF13180 PDZ domain 307 395 4.7E-20 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_15810 a99e5a9ff33eb4bfb354b73c82badbb0 518 SUPERFAMILY SSF50156 425 516 1.71E-9 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 TSH58p_15810 a99e5a9ff33eb4bfb354b73c82badbb0 518 Gene3D G3DSA:2.40.10.120 54 300 2.1E-82 T 14-10-2018 TSH58p_15810 a99e5a9ff33eb4bfb354b73c82badbb0 518 SUPERFAMILY SSF50156 289 395 6.2E-24 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 TSH58p_15810 a99e5a9ff33eb4bfb354b73c82badbb0 518 Pfam PF13365 Trypsin-like peptidase domain 134 268 2.8E-33 T 14-10-2018 TSH58p_15810 a99e5a9ff33eb4bfb354b73c82badbb0 518 SMART SM00228 423 506 0.21 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_15810 a99e5a9ff33eb4bfb354b73c82badbb0 518 SMART SM00228 307 389 6.8E-17 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_15810 a99e5a9ff33eb4bfb354b73c82badbb0 518 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 56 511 3.2E-151 T 14-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 TSH58p_15810 a99e5a9ff33eb4bfb354b73c82badbb0 518 Gene3D G3DSA:2.30.42.60 415 518 1.8E-12 T 14-10-2018 TSH58p_15810 a99e5a9ff33eb4bfb354b73c82badbb0 518 Gene3D G3DSA:2.30.42.10 302 407 2.2E-31 T 14-10-2018 TSH58p_15810 a99e5a9ff33eb4bfb354b73c82badbb0 518 PRINTS PR00834 HtrA/DegQ protease family signature 143 155 1.2E-54 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_15810 a99e5a9ff33eb4bfb354b73c82badbb0 518 PRINTS PR00834 HtrA/DegQ protease family signature 164 184 1.2E-54 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_15810 a99e5a9ff33eb4bfb354b73c82badbb0 518 PRINTS PR00834 HtrA/DegQ protease family signature 347 359 1.2E-54 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_15810 a99e5a9ff33eb4bfb354b73c82badbb0 518 PRINTS PR00834 HtrA/DegQ protease family signature 261 278 1.2E-54 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_15810 a99e5a9ff33eb4bfb354b73c82badbb0 518 PRINTS PR00834 HtrA/DegQ protease family signature 205 229 1.2E-54 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_15810 a99e5a9ff33eb4bfb354b73c82badbb0 518 PRINTS PR00834 HtrA/DegQ protease family signature 239 256 1.2E-54 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_15810 a99e5a9ff33eb4bfb354b73c82badbb0 518 SUPERFAMILY SSF50494 41 316 6.74E-64 T 14-10-2018 IPR009003 Peptidase S1, PA clan TSH58p_15985 b395ffea73bd0a0125ff3977e627e378 336 Pfam PF08238 Sel1 repeat 64 99 5.6E-6 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_15985 b395ffea73bd0a0125ff3977e627e378 336 Pfam PF08238 Sel1 repeat 100 136 2.7E-7 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_15985 b395ffea73bd0a0125ff3977e627e378 336 SUPERFAMILY SSF81901 48 139 1.83E-15 T 14-10-2018 TSH58p_15985 b395ffea73bd0a0125ff3977e627e378 336 Gene3D G3DSA:1.10.530.10 164 300 4.8E-40 T 14-10-2018 TSH58p_15985 b395ffea73bd0a0125ff3977e627e378 336 Pfam PF01464 Transglycosylase SLT domain 184 282 1.3E-24 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 TSH58p_15985 b395ffea73bd0a0125ff3977e627e378 336 SMART SM00671 64 99 1.2E-7 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_15985 b395ffea73bd0a0125ff3977e627e378 336 SMART SM00671 100 136 6.1E-6 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_15985 b395ffea73bd0a0125ff3977e627e378 336 Gene3D G3DSA:1.25.40.10 19 161 9.4E-22 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_15985 b395ffea73bd0a0125ff3977e627e378 336 SUPERFAMILY SSF53955 174 299 7.13E-43 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily TSH58p_24650 26221e716de2bfd5dd486d4aa548ec66 144 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 4 130 1.6E-5 T 14-10-2018 IPR028973 PhnB-like TSH58p_24650 26221e716de2bfd5dd486d4aa548ec66 144 SUPERFAMILY SSF54593 3 133 6.42E-28 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSH58p_24650 26221e716de2bfd5dd486d4aa548ec66 144 Gene3D G3DSA:3.10.180.10 7 139 4.4E-37 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSH58p_31880 facd07cfe04e4c17de521d474a62552d 564 Gene3D G3DSA:1.10.3720.10 307 559 4.8E-21 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_31880 facd07cfe04e4c17de521d474a62552d 564 Gene3D G3DSA:1.10.3720.10 26 289 7.2E-59 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_31880 facd07cfe04e4c17de521d474a62552d 564 SUPERFAMILY SSF161098 27 284 5.98E-55 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_31880 facd07cfe04e4c17de521d474a62552d 564 SUPERFAMILY SSF161098 316 549 1.5E-25 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_31880 facd07cfe04e4c17de521d474a62552d 564 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 276 2.2E-13 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_09645 459c085aa6647d4c3130c00eb751d451 404 SUPERFAMILY SSF81606 252 400 3.92E-5 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSH58p_09645 459c085aa6647d4c3130c00eb751d451 404 Gene3D G3DSA:3.60.40.10 141 403 3.6E-44 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSH58p_09645 459c085aa6647d4c3130c00eb751d451 404 SMART SM00448 13 127 5.1E-38 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_09645 459c085aa6647d4c3130c00eb751d451 404 SUPERFAMILY SSF52172 6 146 3.98E-42 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_09645 459c085aa6647d4c3130c00eb751d451 404 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 215 402 2.9E-36 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSH58p_09645 459c085aa6647d4c3130c00eb751d451 404 Pfam PF00072 Response regulator receiver domain 15 127 9.2E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_09645 459c085aa6647d4c3130c00eb751d451 404 Gene3D G3DSA:3.40.50.2300 9 140 1.8E-40 T 14-10-2018 TSH58p_09645 459c085aa6647d4c3130c00eb751d451 404 SMART SM00331 174 402 1.0E-8 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSH58p_01605 b59e03214193e15fd5cb081d947ff754 190 SMART SM01266 10 64 5.3E-20 T 14-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 TSH58p_01605 b59e03214193e15fd5cb081d947ff754 190 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 143 171 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 TSH58p_01605 b59e03214193e15fd5cb081d947ff754 190 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 135 169 1.2E-9 T 14-10-2018 IPR001451 Hexapeptide repeat TSH58p_01605 b59e03214193e15fd5cb081d947ff754 190 SUPERFAMILY SSF51161 9 189 6.79E-48 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily TSH58p_01605 b59e03214193e15fd5cb081d947ff754 190 Gene3D G3DSA:2.160.10.10 4 189 5.7E-65 T 14-10-2018 TSH58p_01605 b59e03214193e15fd5cb081d947ff754 190 Pfam PF12464 Maltose acetyltransferase 12 62 2.6E-17 T 14-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 TSH58p_24320 f4e2cd9392f48c9cfae8c236e4dc6d14 390 Pfam PF01098 Cell cycle protein 36 378 8.8E-98 T 14-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_24320 f4e2cd9392f48c9cfae8c236e4dc6d14 390 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 30 378 3.5E-124 T 14-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_24320 f4e2cd9392f48c9cfae8c236e4dc6d14 390 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 336 360 - T 14-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_24320 f4e2cd9392f48c9cfae8c236e4dc6d14 390 Hamap MF_02079 Peptidoglycan glycosyltransferase MrdB [mrdB]. 24 381 26.799 T 14-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_27990 152fe22eacd679cfecaf3f06817f6f64 165 SUPERFAMILY SSF103642 143 164 1.1E-8 T 14-10-2018 TSH58p_27990 152fe22eacd679cfecaf3f06817f6f64 165 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 5 133 26.33 T 14-10-2018 IPR023006 Uncharacterised protein family UPF0225 TSH58p_27990 152fe22eacd679cfecaf3f06817f6f64 165 SUPERFAMILY SSF54427 29 133 6.1E-39 T 14-10-2018 IPR032710 NTF2-like domain superfamily TSH58p_27990 152fe22eacd679cfecaf3f06817f6f64 165 Pfam PF02810 SEC-C motif 146 163 3.1E-11 T 14-10-2018 IPR004027 SEC-C motif TSH58p_27990 152fe22eacd679cfecaf3f06817f6f64 165 Gene3D G3DSA:3.10.450.50 5 165 1.7E-59 T 14-10-2018 TSH58p_28730 b8688d0cc9a068810f10a01d8552d3f2 349 Gene3D G3DSA:3.40.50.720 3 269 8.5E-76 T 14-10-2018 TSH58p_28730 b8688d0cc9a068810f10a01d8552d3f2 349 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 193 5.4E-5 T 14-10-2018 TSH58p_28730 b8688d0cc9a068810f10a01d8552d3f2 349 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 2.8E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_28730 b8688d0cc9a068810f10a01d8552d3f2 349 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 2.8E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_28730 b8688d0cc9a068810f10a01d8552d3f2 349 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.8E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_28730 b8688d0cc9a068810f10a01d8552d3f2 349 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.8E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_28730 b8688d0cc9a068810f10a01d8552d3f2 349 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.8E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_28730 b8688d0cc9a068810f10a01d8552d3f2 349 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.8E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_28730 b8688d0cc9a068810f10a01d8552d3f2 349 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_28730 b8688d0cc9a068810f10a01d8552d3f2 349 Pfam PF00106 short chain dehydrogenase 8 196 2.4E-57 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_28730 b8688d0cc9a068810f10a01d8552d3f2 349 SUPERFAMILY SSF51735 7 261 8.89E-74 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_28730 b8688d0cc9a068810f10a01d8552d3f2 349 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.1E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_28730 b8688d0cc9a068810f10a01d8552d3f2 349 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.1E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_28730 b8688d0cc9a068810f10a01d8552d3f2 349 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.1E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_26450 0c1c6cf4b3de3f13b2528168b095626f 212 Gene3D G3DSA:2.40.50.180 98 163 1.6E-9 T 14-10-2018 TSH58p_26450 0c1c6cf4b3de3f13b2528168b095626f 212 Gene3D G3DSA:2.30.30.40 87 184 1.6E-9 T 14-10-2018 TSH58p_26450 0c1c6cf4b3de3f13b2528168b095626f 212 SUPERFAMILY SSF50341 85 205 1.7E-16 T 14-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 TSH58p_26450 0c1c6cf4b3de3f13b2528168b095626f 212 SMART SM00260 72 203 2.3E-4 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TSH58p_26450 0c1c6cf4b3de3f13b2528168b095626f 212 Pfam PF01584 CheW-like domain 87 205 3.0E-14 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TSH58p_11830 265722a1321b5fdcd45c37d62550afe5 145 SUPERFAMILY SSF55174 22 107 3.01E-24 T 14-10-2018 TSH58p_11830 265722a1321b5fdcd45c37d62550afe5 145 Pfam PF01479 S4 domain 24 70 7.4E-12 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_11830 265722a1321b5fdcd45c37d62550afe5 145 Gene3D G3DSA:3.10.290.10 17 118 1.2E-34 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TSH58p_11830 265722a1321b5fdcd45c37d62550afe5 145 SMART SM00363 23 85 2.3E-10 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_07205 d024d894d32c53fc8f06a92ca46d4a4d 150 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 11 93 3.3E-6 T 14-10-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component TSH58p_07205 d024d894d32c53fc8f06a92ca46d4a4d 150 TIGRFAM TIGR01725 phge_HK97_gp10: phage protein, HK97 gp10 family 11 140 2.1E-9 T 14-10-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component TSH58p_11730 44edeb94139caadbf214535e5055bd0b 151 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 3 131 1.2E-31 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type TSH58p_11730 44edeb94139caadbf214535e5055bd0b 151 SUPERFAMILY SSF46785 3 131 1.77E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_11730 44edeb94139caadbf214535e5055bd0b 151 Pfam PF02082 Transcriptional regulator 3 84 7.8E-23 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type TSH58p_11730 44edeb94139caadbf214535e5055bd0b 151 Gene3D G3DSA:1.10.10.10 1 145 4.1E-35 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_25570 e2d2292cf3a2854e6b74ff67abd8c368 937 SUPERFAMILY SSF50692 632 777 6.01E-38 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TSH58p_25570 e2d2292cf3a2854e6b74ff67abd8c368 937 Gene3D G3DSA:3.40.228.10 187 621 9.5E-164 T 14-10-2018 TSH58p_25570 e2d2292cf3a2854e6b74ff67abd8c368 937 Pfam PF01568 Molydopterin dinucleotide binding domain 636 747 3.4E-28 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TSH58p_25570 e2d2292cf3a2854e6b74ff67abd8c368 937 SUPERFAMILY SSF53706 54 623 1.22E-184 T 14-10-2018 TSH58p_25570 e2d2292cf3a2854e6b74ff67abd8c368 937 Pfam PF04324 BFD-like [2Fe-2S] binding domain 880 929 4.8E-15 T 14-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain TSH58p_25570 e2d2292cf3a2854e6b74ff67abd8c368 937 Pfam PF00384 Molybdopterin oxidoreductase 119 537 6.3E-76 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_25570 e2d2292cf3a2854e6b74ff67abd8c368 937 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 56 104 2.0E-18 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_25570 e2d2292cf3a2854e6b74ff67abd8c368 937 Gene3D G3DSA:1.10.10.1100 880 933 4.6E-8 T 14-10-2018 TSH58p_25570 e2d2292cf3a2854e6b74ff67abd8c368 937 PIRSF PIRSF036643 39 759 1.2E-134 T 14-10-2018 TSH58p_25570 e2d2292cf3a2854e6b74ff67abd8c368 937 Gene3D G3DSA:3.40.50.740 121 617 9.5E-164 T 14-10-2018 TSH58p_25570 e2d2292cf3a2854e6b74ff67abd8c368 937 Gene3D G3DSA:2.20.25.90 51 106 1.0E-16 T 14-10-2018 TSH58p_25570 e2d2292cf3a2854e6b74ff67abd8c368 937 Gene3D G3DSA:2.40.40.20 632 757 3.0E-31 T 14-10-2018 TSH58p_25570 e2d2292cf3a2854e6b74ff67abd8c368 937 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 58 76 - T 14-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 TSH58p_25570 e2d2292cf3a2854e6b74ff67abd8c368 937 SMART SM00926 53 107 1.2E-17 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_02720 45b3941c45d37f889b36ec4bb94fdcf0 361 SUPERFAMILY SSF47413 19 65 3.31E-13 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_02720 45b3941c45d37f889b36ec4bb94fdcf0 361 Pfam PF13407 Periplasmic binding protein domain 134 332 5.2E-40 T 14-10-2018 IPR025997 Periplasmic binding protein TSH58p_02720 45b3941c45d37f889b36ec4bb94fdcf0 361 SMART SM00354 18 88 2.6E-13 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TSH58p_02720 45b3941c45d37f889b36ec4bb94fdcf0 361 ProSitePatterns PS00356 LacI-type HTH domain signature. 21 39 - T 14-10-2018 TSH58p_02720 45b3941c45d37f889b36ec4bb94fdcf0 361 Gene3D G3DSA:3.40.50.2300 182 315 8.8E-41 T 14-10-2018 TSH58p_02720 45b3941c45d37f889b36ec4bb94fdcf0 361 Gene3D G3DSA:3.40.50.2300 134 324 8.8E-41 T 14-10-2018 TSH58p_02720 45b3941c45d37f889b36ec4bb94fdcf0 361 Pfam PF00356 Bacterial regulatory proteins, lacI family 21 64 2.1E-16 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TSH58p_02720 45b3941c45d37f889b36ec4bb94fdcf0 361 SUPERFAMILY SSF53822 77 340 9.62E-44 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_02720 45b3941c45d37f889b36ec4bb94fdcf0 361 Gene3D G3DSA:1.10.260.40 13 72 1.4E-16 T 14-10-2018 TSH58p_31690 0db282219cc3108db6e978045ade397e 243 SMART SM00895 102 224 7.9E-17 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_31690 0db282219cc3108db6e978045ade397e 243 SUPERFAMILY SSF48008 101 226 2.07E-22 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_31690 0db282219cc3108db6e978045ade397e 243 SUPERFAMILY SSF46785 29 118 7.36E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_31690 0db282219cc3108db6e978045ade397e 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 33 86 2.6E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_31690 0db282219cc3108db6e978045ade397e 243 Gene3D G3DSA:1.10.10.10 27 93 5.1E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_31690 0db282219cc3108db6e978045ade397e 243 SMART SM00345 34 92 7.3E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_31690 0db282219cc3108db6e978045ade397e 243 Gene3D G3DSA:1.20.120.530 98 225 2.2E-25 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_31690 0db282219cc3108db6e978045ade397e 243 Pfam PF07729 FCD domain 102 220 2.8E-23 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_08315 8faf105aac025ba5e92ec38a14940d2b 242 Pfam PF00005 ABC transporter 19 167 2.4E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_08315 8faf105aac025ba5e92ec38a14940d2b 242 SUPERFAMILY SSF52540 3 236 2.96E-77 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_08315 8faf105aac025ba5e92ec38a14940d2b 242 SMART SM00382 28 215 2.6E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_08315 8faf105aac025ba5e92ec38a14940d2b 242 Gene3D G3DSA:3.40.50.300 3 242 5.6E-78 T 14-10-2018 TSH58p_08315 8faf105aac025ba5e92ec38a14940d2b 242 PIRSF PIRSF039085 1 242 7.2E-109 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 TSH58p_08315 8faf105aac025ba5e92ec38a14940d2b 242 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_26140 e7b50addc21c43e8573f5f504c6806d2 410 Pfam PF00512 His Kinase A (phospho-acceptor) domain 168 228 1.8E-7 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_26140 e7b50addc21c43e8573f5f504c6806d2 410 SUPERFAMILY SSF55874 255 404 1.15E-29 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_26140 e7b50addc21c43e8573f5f504c6806d2 410 Gene3D G3DSA:3.30.565.10 253 407 8.0E-28 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_26140 e7b50addc21c43e8573f5f504c6806d2 410 Gene3D G3DSA:3.40.50.2300 9 145 2.2E-35 T 14-10-2018 TSH58p_26140 e7b50addc21c43e8573f5f504c6806d2 410 SMART SM00448 15 127 1.1E-35 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_26140 e7b50addc21c43e8573f5f504c6806d2 410 Pfam PF00072 Response regulator receiver domain 17 127 3.5E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_26140 e7b50addc21c43e8573f5f504c6806d2 410 SMART SM00387 293 406 5.4E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_26140 e7b50addc21c43e8573f5f504c6806d2 410 SUPERFAMILY SSF47384 155 212 6.47E-8 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_26140 e7b50addc21c43e8573f5f504c6806d2 410 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 299 405 8.9E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_26140 e7b50addc21c43e8573f5f504c6806d2 410 Gene3D G3DSA:1.10.287.130 146 246 9.5E-15 T 14-10-2018 TSH58p_26140 e7b50addc21c43e8573f5f504c6806d2 410 SUPERFAMILY SSF52172 13 148 3.84E-38 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_26140 e7b50addc21c43e8573f5f504c6806d2 410 PRINTS PR00344 Bacterial sensor protein C-terminal signature 334 348 8.0E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_26140 e7b50addc21c43e8573f5f504c6806d2 410 PRINTS PR00344 Bacterial sensor protein C-terminal signature 390 403 8.0E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_26140 e7b50addc21c43e8573f5f504c6806d2 410 PRINTS PR00344 Bacterial sensor protein C-terminal signature 352 362 8.0E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_26140 e7b50addc21c43e8573f5f504c6806d2 410 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 383 8.0E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_26140 e7b50addc21c43e8573f5f504c6806d2 410 SMART SM00388 168 239 7.2E-5 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_08005 f3ae935a9bcf54833bfed7957a870162 293 Pfam PF02634 FdhD/NarQ family 37 268 2.6E-70 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 TSH58p_08005 f3ae935a9bcf54833bfed7957a870162 293 SUPERFAMILY SSF53927 19 268 1.99E-71 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TSH58p_08005 f3ae935a9bcf54833bfed7957a870162 293 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 15 269 26.063 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 TSH58p_08005 f3ae935a9bcf54833bfed7957a870162 293 PIRSF PIRSF015626 7 273 1.7E-83 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 TSH58p_08005 f3ae935a9bcf54833bfed7957a870162 293 Gene3D G3DSA:3.10.20.10 38 120 8.3E-9 T 14-10-2018 TSH58p_08005 f3ae935a9bcf54833bfed7957a870162 293 Gene3D G3DSA:3.40.140.10 125 274 2.1E-37 T 14-10-2018 TSH58p_08005 f3ae935a9bcf54833bfed7957a870162 293 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 34 262 2.2E-43 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 TSH58p_26460 cc6d5058af942463cd0dc13f0aa0f85c 188 SMART SM00260 5 144 2.7E-8 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TSH58p_26460 cc6d5058af942463cd0dc13f0aa0f85c 188 Pfam PF01584 CheW-like domain 10 147 1.2E-17 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TSH58p_26460 cc6d5058af942463cd0dc13f0aa0f85c 188 SUPERFAMILY SSF50341 4 148 9.16E-22 T 14-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 TSH58p_26460 cc6d5058af942463cd0dc13f0aa0f85c 188 Gene3D G3DSA:2.30.30.40 11 110 3.9E-14 T 14-10-2018 TSH58p_26460 cc6d5058af942463cd0dc13f0aa0f85c 188 Gene3D G3DSA:2.40.50.180 28 94 3.9E-14 T 14-10-2018 TSH58p_32220 75d7592308f4239caeace64c307336c1 313 SUPERFAMILY SSF51445 15 276 6.21E-19 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_32220 75d7592308f4239caeace64c307336c1 313 Pfam PF00704 Glycosyl hydrolases family 18 16 167 2.5E-7 T 14-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 TSH58p_32220 75d7592308f4239caeace64c307336c1 313 Gene3D G3DSA:3.20.20.80 8 277 1.8E-17 T 14-10-2018 TSH58p_24240 2b4e3ccf29026c1bb9140ded15750b76 482 TIGRFAM TIGR03356 BGL: beta-galactosidase 40 469 2.3E-173 T 14-10-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092|MetaCyc: PWY-7913 TSH58p_24240 2b4e3ccf29026c1bb9140ded15750b76 482 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 27 9.6E-4 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal TSH58p_24240 2b4e3ccf29026c1bb9140ded15750b76 482 Gene3D G3DSA:3.20.20.80 34 479 1.5E-159 T 14-10-2018 TSH58p_24240 2b4e3ccf29026c1bb9140ded15750b76 482 Pfam PF00232 Glycosyl hydrolase family 1 39 477 5.0E-143 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSH58p_24240 2b4e3ccf29026c1bb9140ded15750b76 482 PRINTS PR00131 Glycosyl hydrolase family 1 signature 381 389 4.3E-20 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSH58p_24240 2b4e3ccf29026c1bb9140ded15750b76 482 PRINTS PR00131 Glycosyl hydrolase family 1 signature 402 413 4.3E-20 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSH58p_24240 2b4e3ccf29026c1bb9140ded15750b76 482 PRINTS PR00131 Glycosyl hydrolase family 1 signature 447 459 4.3E-20 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSH58p_24240 2b4e3ccf29026c1bb9140ded15750b76 482 PRINTS PR00131 Glycosyl hydrolase family 1 signature 423 440 4.3E-20 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSH58p_24240 2b4e3ccf29026c1bb9140ded15750b76 482 PRINTS PR00131 Glycosyl hydrolase family 1 signature 318 332 4.3E-20 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSH58p_24240 2b4e3ccf29026c1bb9140ded15750b76 482 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 381 389 - T 14-10-2018 IPR018120 Glycoside hydrolase family 1, active site TSH58p_24240 2b4e3ccf29026c1bb9140ded15750b76 482 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 44 58 - T 14-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site TSH58p_24240 2b4e3ccf29026c1bb9140ded15750b76 482 SUPERFAMILY SSF51445 39 479 6.35E-154 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_10575 efca551e807b199e492cf8d68768633d 639 Gene3D G3DSA:2.60.34.10 378 518 3.7E-66 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 TSH58p_10575 efca551e807b199e492cf8d68768633d 639 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 631 37.887 T 14-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 TSH58p_10575 efca551e807b199e492cf8d68768633d 639 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 332 346 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 TSH58p_10575 efca551e807b199e492cf8d68768633d 639 Gene3D G3DSA:3.30.420.40 184 357 3.7E-163 T 14-10-2018 TSH58p_10575 efca551e807b199e492cf8d68768633d 639 SUPERFAMILY SSF53067 1 183 2.54E-65 T 14-10-2018 TSH58p_10575 efca551e807b199e492cf8d68768633d 639 SUPERFAMILY SSF100920 379 535 7.32E-63 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 TSH58p_10575 efca551e807b199e492cf8d68768633d 639 SUPERFAMILY SSF53067 187 377 1.23E-67 T 14-10-2018 TSH58p_10575 efca551e807b199e492cf8d68768633d 639 Gene3D G3DSA:3.30.420.40 5 372 3.7E-163 T 14-10-2018 TSH58p_10575 efca551e807b199e492cf8d68768633d 639 Gene3D G3DSA:3.30.30.30 67 118 3.7E-163 T 14-10-2018 TSH58p_10575 efca551e807b199e492cf8d68768633d 639 Gene3D G3DSA:1.20.1270.10 519 601 1.8E-28 T 14-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 TSH58p_10575 efca551e807b199e492cf8d68768633d 639 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 191 204 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 TSH58p_10575 efca551e807b199e492cf8d68768633d 639 Pfam PF00012 Hsp70 protein 4 599 1.1E-276 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TSH58p_10575 efca551e807b199e492cf8d68768633d 639 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 599 1.6E-301 T 14-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 TSH58p_10575 efca551e807b199e492cf8d68768633d 639 PRINTS PR00301 70kDa heat shock protein signature 31 43 6.1E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TSH58p_10575 efca551e807b199e492cf8d68768633d 639 PRINTS PR00301 70kDa heat shock protein signature 360 380 6.1E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TSH58p_10575 efca551e807b199e492cf8d68768633d 639 PRINTS PR00301 70kDa heat shock protein signature 54 62 6.1E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TSH58p_10575 efca551e807b199e492cf8d68768633d 639 PRINTS PR00301 70kDa heat shock protein signature 197 207 6.1E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TSH58p_10575 efca551e807b199e492cf8d68768633d 639 PRINTS PR00301 70kDa heat shock protein signature 138 158 6.1E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TSH58p_10575 efca551e807b199e492cf8d68768633d 639 PRINTS PR00301 70kDa heat shock protein signature 464 480 6.1E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TSH58p_10575 efca551e807b199e492cf8d68768633d 639 PRINTS PR00301 70kDa heat shock protein signature 3 16 6.1E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TSH58p_10575 efca551e807b199e492cf8d68768633d 639 PRINTS PR00301 70kDa heat shock protein signature 329 345 6.1E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TSH58p_10575 efca551e807b199e492cf8d68768633d 639 PRINTS PR00301 70kDa heat shock protein signature 383 402 6.1E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TSH58p_10575 efca551e807b199e492cf8d68768633d 639 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 TSH58p_10575 efca551e807b199e492cf8d68768633d 639 SUPERFAMILY SSF100934 502 600 8.63E-20 T 14-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 TSH58p_10575 efca551e807b199e492cf8d68768633d 639 Gene3D G3DSA:3.90.640.10 223 310 3.7E-163 T 14-10-2018 TSH58p_08885 4351c5fabf9433c6177ab6ff948a9ef3 506 Gene3D G3DSA:3.40.309.10 266 464 7.6E-168 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TSH58p_08885 4351c5fabf9433c6177ab6ff948a9ef3 506 Pfam PF00171 Aldehyde dehydrogenase family 27 493 4.6E-170 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TSH58p_08885 4351c5fabf9433c6177ab6ff948a9ef3 506 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 261 268 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 TSH58p_08885 4351c5fabf9433c6177ab6ff948a9ef3 506 SUPERFAMILY SSF53720 11 498 8.12E-167 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSH58p_08885 4351c5fabf9433c6177ab6ff948a9ef3 506 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 294 305 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 TSH58p_08885 4351c5fabf9433c6177ab6ff948a9ef3 506 Gene3D G3DSA:3.40.605.10 23 492 7.6E-168 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TSH58p_09130 31f6b023932f4a76cad68999e151791c 530 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 331 338 8.5E-8 T 14-10-2018 TSH58p_09130 31f6b023932f4a76cad68999e151791c 530 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 8.5E-8 T 14-10-2018 TSH58p_09130 31f6b023932f4a76cad68999e151791c 530 Gene3D G3DSA:1.20.58.100 397 498 1.4E-13 T 14-10-2018 TSH58p_09130 31f6b023932f4a76cad68999e151791c 530 Pfam PF00890 FAD binding domain 11 217 3.5E-14 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_09130 31f6b023932f4a76cad68999e151791c 530 PIRSF PIRSF000171 1 224 2.7E-22 T 14-10-2018 TSH58p_09130 31f6b023932f4a76cad68999e151791c 530 PIRSF PIRSF000171 307 528 7.3E-10 T 14-10-2018 TSH58p_09130 31f6b023932f4a76cad68999e151791c 530 SUPERFAMILY SSF51905 7 375 1.05E-43 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_09130 31f6b023932f4a76cad68999e151791c 530 Pfam PF02910 Fumarate reductase flavoprotein C-term 427 499 6.6E-7 T 14-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_09130 31f6b023932f4a76cad68999e151791c 530 Gene3D G3DSA:3.50.50.60 307 367 5.6E-6 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_09130 31f6b023932f4a76cad68999e151791c 530 SUPERFAMILY SSF46977 426 523 4.06E-19 T 14-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_09130 31f6b023932f4a76cad68999e151791c 530 Gene3D G3DSA:3.50.50.60 3 242 1.1E-44 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_09130 31f6b023932f4a76cad68999e151791c 530 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 316 338 8.9E-18 T 14-10-2018 TSH58p_09130 31f6b023932f4a76cad68999e151791c 530 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 8.9E-18 T 14-10-2018 TSH58p_09130 31f6b023932f4a76cad68999e151791c 530 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 175 193 8.9E-18 T 14-10-2018 TSH58p_28670 a42aa35f630f8f812de3b977d3308e3a 599 SUPERFAMILY SSF52016 417 597 5.41E-58 T 14-10-2018 TSH58p_28670 a42aa35f630f8f812de3b977d3308e3a 599 Pfam PF00920 Dehydratase family 69 595 3.7E-161 T 14-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TSH58p_28670 a42aa35f630f8f812de3b977d3308e3a 599 Gene3D G3DSA:3.50.30.80 417 566 7.3E-52 T 14-10-2018 TSH58p_28670 a42aa35f630f8f812de3b977d3308e3a 599 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 503 514 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TSH58p_28670 a42aa35f630f8f812de3b977d3308e3a 599 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 157 167 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TSH58p_28670 a42aa35f630f8f812de3b977d3308e3a 599 SUPERFAMILY SSF143975 3 416 3.92E-134 T 14-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TSH58p_28670 a42aa35f630f8f812de3b977d3308e3a 599 TIGRFAM TIGR01196 edd: phosphogluconate dehydratase 4 598 2.5E-280 T 14-10-2018 IPR004786 6-phosphogluconate dehydratase GO:0004456|GO:0009255 KEGG: 00030+4.2.1.12 TSH58p_28670 a42aa35f630f8f812de3b977d3308e3a 599 Hamap MF_02094 Phosphogluconate dehydratase [edd]. 3 599 56.376 T 14-10-2018 TSH58p_06435 52ddca1f6030cc42726cddf8fb870308 277 SUPERFAMILY SSF53167 4 267 1.81E-85 T 14-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TSH58p_06435 52ddca1f6030cc42726cddf8fb870308 277 PIRSF PIRSF000477 1 269 4.9E-102 T 14-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 TSH58p_06435 52ddca1f6030cc42726cddf8fb870308 277 Pfam PF01048 Phosphorylase superfamily 20 267 1.8E-49 T 14-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TSH58p_06435 52ddca1f6030cc42726cddf8fb870308 277 Gene3D G3DSA:3.40.50.1580 1 269 1.9E-102 T 14-10-2018 TSH58p_06435 52ddca1f6030cc42726cddf8fb870308 277 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 20 265 6.2E-98 T 14-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 TSH58p_26990 71418cd25f7d432f49d1b0ffcaff008e 283 Pfam PF13432 Tetratricopeptide repeat 197 247 2.6E-5 T 14-10-2018 TSH58p_26990 71418cd25f7d432f49d1b0ffcaff008e 283 Pfam PF13371 Tetratricopeptide repeat 120 188 1.1E-10 T 14-10-2018 TSH58p_26990 71418cd25f7d432f49d1b0ffcaff008e 283 Gene3D G3DSA:1.25.40.10 16 154 2.4E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_26990 71418cd25f7d432f49d1b0ffcaff008e 283 SUPERFAMILY SSF48452 116 250 1.93E-25 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_26990 71418cd25f7d432f49d1b0ffcaff008e 283 SMART SM00028 112 145 0.1 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_26990 71418cd25f7d432f49d1b0ffcaff008e 283 SMART SM00028 214 247 4.4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_26990 71418cd25f7d432f49d1b0ffcaff008e 283 SMART SM00028 180 213 0.01 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_26990 71418cd25f7d432f49d1b0ffcaff008e 283 SMART SM00028 146 179 19.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_26990 71418cd25f7d432f49d1b0ffcaff008e 283 Gene3D G3DSA:1.25.40.10 155 277 4.9E-20 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_20440 a461ca964c80801b308bc48db774cfb7 366 SUPERFAMILY SSF81271 282 363 2.83E-35 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 TSH58p_20440 a461ca964c80801b308bc48db774cfb7 366 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 366 44.25 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 TSH58p_20440 a461ca964c80801b308bc48db774cfb7 366 Gene3D G3DSA:1.10.150.300 114 201 2.6E-152 T 14-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 TSH58p_20440 a461ca964c80801b308bc48db774cfb7 366 SUPERFAMILY SSF52540 3 304 3.78E-82 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_20440 a461ca964c80801b308bc48db774cfb7 366 Pfam PF01926 50S ribosome-binding GTPase 5 117 1.0E-23 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 TSH58p_20440 a461ca964c80801b308bc48db774cfb7 366 Gene3D G3DSA:3.40.50.300 4 281 2.6E-152 T 14-10-2018 TSH58p_20440 a461ca964c80801b308bc48db774cfb7 366 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 366 1.0E-153 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 TSH58p_20440 a461ca964c80801b308bc48db774cfb7 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.0E-33 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 TSH58p_20440 a461ca964c80801b308bc48db774cfb7 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 71 86 1.0E-33 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 TSH58p_20440 a461ca964c80801b308bc48db774cfb7 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 27 45 1.0E-33 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 TSH58p_20440 a461ca964c80801b308bc48db774cfb7 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 88 106 1.0E-33 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 TSH58p_20440 a461ca964c80801b308bc48db774cfb7 366 PIRSF PIRSF006641 1 366 9.6E-158 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 TSH58p_20440 a461ca964c80801b308bc48db774cfb7 366 Pfam PF06071 Protein of unknown function (DUF933) 282 365 3.0E-39 T 14-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 TSH58p_20440 a461ca964c80801b308bc48db774cfb7 366 Gene3D G3DSA:3.10.20.30 49 364 2.6E-152 T 14-10-2018 IPR012675 Beta-grasp domain superfamily TSH58p_19245 677f1a9c645e7daa76491b16910a65df 418 SUPERFAMILY SSF64518 1 418 2.09E-55 T 14-10-2018 TSH58p_19245 677f1a9c645e7daa76491b16910a65df 418 Pfam PF00669 Bacterial flagellin N-terminal helical region 4 134 2.7E-21 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 TSH58p_19245 677f1a9c645e7daa76491b16910a65df 418 Gene3D G3DSA:3.30.70.2120 182 315 1.4E-7 T 14-10-2018 TSH58p_19245 677f1a9c645e7daa76491b16910a65df 418 PRINTS PR00207 Flagellin signature 36 53 1.2E-6 T 14-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 TSH58p_19245 677f1a9c645e7daa76491b16910a65df 418 PRINTS PR00207 Flagellin signature 75 94 1.2E-6 T 14-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 TSH58p_19245 677f1a9c645e7daa76491b16910a65df 418 PRINTS PR00207 Flagellin signature 107 130 1.2E-6 T 14-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 TSH58p_19245 677f1a9c645e7daa76491b16910a65df 418 Gene3D G3DSA:1.10.8.410 371 418 1.4E-6 T 14-10-2018 TSH58p_19245 677f1a9c645e7daa76491b16910a65df 418 Gene3D G3DSA:1.20.1330.10 44 358 1.4E-7 T 14-10-2018 TSH58p_19245 677f1a9c645e7daa76491b16910a65df 418 Pfam PF00700 Bacterial flagellin C-terminal helical region 344 417 2.4E-16 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 TSH58p_21920 f7682c74b062aa97939fada914f6b892 424 Gene3D G3DSA:3.90.1150.10 19 414 9.0E-167 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_21920 f7682c74b062aa97939fada914f6b892 424 SUPERFAMILY SSF53383 14 418 9.85E-123 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_21920 f7682c74b062aa97939fada914f6b892 424 Pfam PF00266 Aminotransferase class-V 42 411 8.5E-143 T 14-10-2018 IPR000192 Aminotransferase class V domain TSH58p_21920 f7682c74b062aa97939fada914f6b892 424 Gene3D G3DSA:3.40.640.10 53 313 9.0E-167 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_21920 f7682c74b062aa97939fada914f6b892 424 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 18 423 3.4E-173 T 14-10-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 TSH58p_02265 528b20974d846be13229dcebe88a3705 215 SMART SM00345 2 58 3.2E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_02265 528b20974d846be13229dcebe88a3705 215 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 58 9.9E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_02265 528b20974d846be13229dcebe88a3705 215 SMART SM00895 68 200 2.6E-14 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_02265 528b20974d846be13229dcebe88a3705 215 Pfam PF07729 FCD domain 68 199 6.1E-20 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_02265 528b20974d846be13229dcebe88a3705 215 SUPERFAMILY SSF46785 3 62 3.0E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_02265 528b20974d846be13229dcebe88a3705 215 Gene3D G3DSA:1.20.120.530 59 204 6.5E-22 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_02265 528b20974d846be13229dcebe88a3705 215 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 18 32 2.1E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_02265 528b20974d846be13229dcebe88a3705 215 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 48 2.1E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_02265 528b20974d846be13229dcebe88a3705 215 Gene3D G3DSA:1.10.10.10 1 58 3.1E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_02265 528b20974d846be13229dcebe88a3705 215 SUPERFAMILY SSF48008 64 208 1.23E-18 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_27360 bbe7054728b0b2c16d0b4711f0063b5a 757 Gene3D G3DSA:3.20.70.20 2 566 1.4E-185 T 14-10-2018 TSH58p_27360 bbe7054728b0b2c16d0b4711f0063b5a 757 Pfam PF02867 Ribonucleotide reductase, barrel domain 84 551 2.2E-133 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSH58p_27360 bbe7054728b0b2c16d0b4711f0063b5a 757 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 7 77 2.0E-9 T 14-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSH58p_27360 bbe7054728b0b2c16d0b4711f0063b5a 757 PRINTS PR01183 Ribonucleotide reductase large chain signature 420 447 1.1E-24 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSH58p_27360 bbe7054728b0b2c16d0b4711f0063b5a 757 PRINTS PR01183 Ribonucleotide reductase large chain signature 299 322 1.1E-24 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSH58p_27360 bbe7054728b0b2c16d0b4711f0063b5a 757 PRINTS PR01183 Ribonucleotide reductase large chain signature 337 359 1.1E-24 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSH58p_27360 bbe7054728b0b2c16d0b4711f0063b5a 757 PRINTS PR01183 Ribonucleotide reductase large chain signature 159 178 1.1E-24 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSH58p_27360 bbe7054728b0b2c16d0b4711f0063b5a 757 PRINTS PR01183 Ribonucleotide reductase large chain signature 365 388 1.1E-24 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSH58p_27360 bbe7054728b0b2c16d0b4711f0063b5a 757 SUPERFAMILY SSF51998 5 569 8.24E-166 T 14-10-2018 TSH58p_27360 bbe7054728b0b2c16d0b4711f0063b5a 757 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 10 559 2.0E-171 T 14-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSH58p_20940 355620f21a446b430a64e6f46523bbdd 254 Gene3D G3DSA:1.10.10.10 12 86 1.9E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_20940 355620f21a446b430a64e6f46523bbdd 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 3.3E-8 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_20940 355620f21a446b430a64e6f46523bbdd 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 3.3E-8 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_20940 355620f21a446b430a64e6f46523bbdd 254 Pfam PF07702 UTRA domain 109 245 1.7E-19 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 TSH58p_20940 355620f21a446b430a64e6f46523bbdd 254 SUPERFAMILY SSF64288 70 252 1.88E-33 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TSH58p_20940 355620f21a446b430a64e6f46523bbdd 254 SUPERFAMILY SSF46785 16 86 6.93E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_20940 355620f21a446b430a64e6f46523bbdd 254 Gene3D G3DSA:3.40.1410.10 92 254 3.2E-28 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TSH58p_20940 355620f21a446b430a64e6f46523bbdd 254 SMART SM00345 23 82 1.6E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_20940 355620f21a446b430a64e6f46523bbdd 254 SMART SM00866 103 245 8.8E-16 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 TSH58p_20940 355620f21a446b430a64e6f46523bbdd 254 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 82 3.9E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_26270 88645f89b9a62414ba39c89f1e010690 590 Pfam PF00391 PEP-utilising enzyme, mobile domain 168 240 1.6E-19 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TSH58p_26270 88645f89b9a62414ba39c89f1e010690 590 SUPERFAMILY SSF51621 264 566 2.62E-97 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSH58p_26270 88645f89b9a62414ba39c89f1e010690 590 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 308 327 1.7E-27 T 14-10-2018 TSH58p_26270 88645f89b9a62414ba39c89f1e010690 590 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 482 497 1.7E-27 T 14-10-2018 TSH58p_26270 88645f89b9a62414ba39c89f1e010690 590 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 518 530 1.7E-27 T 14-10-2018 TSH58p_26270 88645f89b9a62414ba39c89f1e010690 590 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 465 480 1.7E-27 T 14-10-2018 TSH58p_26270 88645f89b9a62414ba39c89f1e010690 590 Gene3D G3DSA:3.20.20.60 249 588 3.6E-111 T 14-10-2018 TSH58p_26270 88645f89b9a62414ba39c89f1e010690 590 Gene3D G3DSA:3.50.30.10 16 248 1.5E-75 T 14-10-2018 TSH58p_26270 88645f89b9a62414ba39c89f1e010690 590 SUPERFAMILY SSF52009 141 260 2.22E-33 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 TSH58p_26270 88645f89b9a62414ba39c89f1e010690 590 Gene3D G3DSA:1.10.274.10 33 161 1.5E-75 T 14-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 TSH58p_26270 88645f89b9a62414ba39c89f1e010690 590 SUPERFAMILY SSF47831 37 157 3.27E-26 T 14-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 TSH58p_26270 88645f89b9a62414ba39c89f1e010690 590 PIRSF PIRSF000732 9 588 3.8E-198 T 14-10-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 TSH58p_26270 88645f89b9a62414ba39c89f1e010690 590 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 266 559 8.4E-97 T 14-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 TSH58p_26270 88645f89b9a62414ba39c89f1e010690 590 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 465 483 - T 14-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 TSH58p_26270 88645f89b9a62414ba39c89f1e010690 590 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 15 583 6.6E-164 T 14-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 TSH58p_26270 88645f89b9a62414ba39c89f1e010690 590 Pfam PF05524 PEP-utilising enzyme, N-terminal 15 141 3.6E-29 T 14-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 TSH58p_04510 62b897b5369f9a4d703c69ad4152cf67 314 SUPERFAMILY SSF50685 57 151 3.45E-10 T 14-10-2018 IPR036908 RlpA-like domain superfamily TSH58p_04510 62b897b5369f9a4d703c69ad4152cf67 314 Pfam PF05036 Sporulation related domain 241 302 2.0E-12 T 14-10-2018 IPR007730 Sporulation-like domain GO:0042834 TSH58p_04510 62b897b5369f9a4d703c69ad4152cf67 314 SUPERFAMILY SSF110997 239 312 3.27E-15 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 TSH58p_04510 62b897b5369f9a4d703c69ad4152cf67 314 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 20 155 24.779 T 14-10-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 TSH58p_04510 62b897b5369f9a4d703c69ad4152cf67 314 Gene3D G3DSA:2.40.40.10 62 156 2.9E-37 T 14-10-2018 IPR036908 RlpA-like domain superfamily TSH58p_04510 62b897b5369f9a4d703c69ad4152cf67 314 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 65 161 9.0E-43 T 14-10-2018 IPR012997 Rare lipoprotein A TSH58p_04510 62b897b5369f9a4d703c69ad4152cf67 314 Pfam PF03330 Lytic transglycolase 63 152 1.6E-23 T 14-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain TSH58p_04510 62b897b5369f9a4d703c69ad4152cf67 314 Gene3D G3DSA:3.30.70.1070 235 313 7.6E-10 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 TSH58p_23540 aa42efcc55db11e37b73f24f5c66b0bf 459 SUPERFAMILY SSF46689 363 452 1.94E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_23540 aa42efcc55db11e37b73f24f5c66b0bf 459 Gene3D G3DSA:3.40.50.300 145 322 2.0E-61 T 14-10-2018 TSH58p_23540 aa42efcc55db11e37b73f24f5c66b0bf 459 Gene3D G3DSA:1.10.10.60 402 455 1.2E-11 T 14-10-2018 TSH58p_23540 aa42efcc55db11e37b73f24f5c66b0bf 459 Gene3D G3DSA:1.10.8.60 323 391 4.0E-19 T 14-10-2018 TSH58p_23540 aa42efcc55db11e37b73f24f5c66b0bf 459 SUPERFAMILY SSF52540 151 381 9.25E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_23540 aa42efcc55db11e37b73f24f5c66b0bf 459 SMART SM00382 172 315 2.6E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_23540 aa42efcc55db11e37b73f24f5c66b0bf 459 SMART SM00448 10 121 3.1E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_23540 aa42efcc55db11e37b73f24f5c66b0bf 459 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 238 253 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 TSH58p_23540 aa42efcc55db11e37b73f24f5c66b0bf 459 Pfam PF02954 Bacterial regulatory protein, Fis family 411 450 9.6E-7 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_23540 aa42efcc55db11e37b73f24f5c66b0bf 459 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 365 374 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site TSH58p_23540 aa42efcc55db11e37b73f24f5c66b0bf 459 Pfam PF00158 Sigma-54 interaction domain 152 318 5.2E-67 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 TSH58p_23540 aa42efcc55db11e37b73f24f5c66b0bf 459 Gene3D G3DSA:3.40.50.2300 10 144 5.0E-36 T 14-10-2018 TSH58p_23540 aa42efcc55db11e37b73f24f5c66b0bf 459 SUPERFAMILY SSF52172 11 195 8.68E-41 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_23540 aa42efcc55db11e37b73f24f5c66b0bf 459 Pfam PF00072 Response regulator receiver domain 12 120 1.5E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_23540 aa42efcc55db11e37b73f24f5c66b0bf 459 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 176 189 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 TSH58p_12565 e16e7c11fed05c461b689e181f1741b1 609 Gene3D G3DSA:3.10.580.10 145 282 2.5E-22 T 14-10-2018 TSH58p_12565 e16e7c11fed05c461b689e181f1741b1 609 Gene3D G3DSA:2.60.120.10 11 141 2.5E-13 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_12565 e16e7c11fed05c461b689e181f1741b1 609 SUPERFAMILY SSF51206 12 134 1.06E-16 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like TSH58p_12565 e16e7c11fed05c461b689e181f1741b1 609 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 464 605 1.6E-42 T 14-10-2018 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding TSH58p_12565 e16e7c11fed05c461b689e181f1741b1 609 SUPERFAMILY SSF54631 150 273 6.06E-21 T 14-10-2018 TSH58p_12565 e16e7c11fed05c461b689e181f1741b1 609 Pfam PF00027 Cyclic nucleotide-binding domain 35 113 1.3E-7 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_12565 e16e7c11fed05c461b689e181f1741b1 609 Pfam PF03445 Putative nucleotidyltransferase DUF294 299 427 7.7E-39 T 14-10-2018 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 TSH58p_12565 e16e7c11fed05c461b689e181f1741b1 609 Pfam PF00571 CBS domain 225 272 1.1E-5 T 14-10-2018 IPR000644 CBS domain TSH58p_12565 e16e7c11fed05c461b689e181f1741b1 609 SMART SM00100 15 130 1.6E-4 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_12565 e16e7c11fed05c461b689e181f1741b1 609 SMART SM00116 225 272 3.7E-4 T 14-10-2018 IPR000644 CBS domain TSH58p_12565 e16e7c11fed05c461b689e181f1741b1 609 SMART SM00116 157 208 0.29 T 14-10-2018 IPR000644 CBS domain TSH58p_13670 16fd84498b17b172304eb078d4f69c3a 137 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 10 80 5.0E-23 T 14-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_13670 16fd84498b17b172304eb078d4f69c3a 137 SUPERFAMILY SSF51344 5 85 1.31E-22 T 14-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_13670 16fd84498b17b172304eb078d4f69c3a 137 Gene3D G3DSA:2.60.15.10 1 130 4.9E-36 T 14-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_13670 16fd84498b17b172304eb078d4f69c3a 137 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 3 131 19.671 T 14-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_13670 16fd84498b17b172304eb078d4f69c3a 137 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 6 84 5.7E-26 T 14-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_13670 16fd84498b17b172304eb078d4f69c3a 137 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 5 132 3.4E-32 T 14-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_12280 6093bca3689cc004a36768a9d1b79220 1217 Pfam PF00072 Response regulator receiver domain 951 1078 2.5E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_12280 6093bca3689cc004a36768a9d1b79220 1217 SUPERFAMILY SSF47384 513 594 1.41E-20 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_12280 6093bca3689cc004a36768a9d1b79220 1217 Pfam PF01627 Hpt domain 1124 1206 2.6E-11 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TSH58p_12280 6093bca3689cc004a36768a9d1b79220 1217 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 640 757 1.2E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_12280 6093bca3689cc004a36768a9d1b79220 1217 Gene3D G3DSA:1.20.1480.50 300 392 1.6E-6 T 14-10-2018 TSH58p_12280 6093bca3689cc004a36768a9d1b79220 1217 SMART SM00387 640 758 2.5E-39 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_12280 6093bca3689cc004a36768a9d1b79220 1217 Gene3D G3DSA:1.10.287.130 506 591 1.9E-26 T 14-10-2018 TSH58p_12280 6093bca3689cc004a36768a9d1b79220 1217 PRINTS PR00344 Bacterial sensor protein C-terminal signature 718 736 4.1E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_12280 6093bca3689cc004a36768a9d1b79220 1217 PRINTS PR00344 Bacterial sensor protein C-terminal signature 742 755 4.1E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_12280 6093bca3689cc004a36768a9d1b79220 1217 PRINTS PR00344 Bacterial sensor protein C-terminal signature 701 711 4.1E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_12280 6093bca3689cc004a36768a9d1b79220 1217 PRINTS PR00344 Bacterial sensor protein C-terminal signature 683 697 4.1E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_12280 6093bca3689cc004a36768a9d1b79220 1217 Pfam PF00512 His Kinase A (phospho-acceptor) domain 528 593 7.8E-18 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_12280 6093bca3689cc004a36768a9d1b79220 1217 SUPERFAMILY SSF47226 1061 1201 4.32E-20 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_12280 6093bca3689cc004a36768a9d1b79220 1217 SUPERFAMILY SSF52172 949 1083 5.83E-33 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_12280 6093bca3689cc004a36768a9d1b79220 1217 SUPERFAMILY SSF55874 582 756 2.36E-45 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_12280 6093bca3689cc004a36768a9d1b79220 1217 Gene3D G3DSA:3.30.450.20 393 505 2.7E-10 T 14-10-2018 TSH58p_12280 6093bca3689cc004a36768a9d1b79220 1217 Gene3D G3DSA:1.20.120.160 1101 1212 1.4E-15 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_12280 6093bca3689cc004a36768a9d1b79220 1217 Pfam PF00672 HAMP domain 340 387 9.0E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_12280 6093bca3689cc004a36768a9d1b79220 1217 Gene3D G3DSA:3.40.50.2300 945 1082 3.2E-36 T 14-10-2018 TSH58p_12280 6093bca3689cc004a36768a9d1b79220 1217 Gene3D G3DSA:1.20.58.920 50 169 2.0E-9 T 14-10-2018 IPR038188 TorS, sensor domain superfamily TSH58p_12280 6093bca3689cc004a36768a9d1b79220 1217 Gene3D G3DSA:3.30.565.10 592 758 1.5E-51 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_12280 6093bca3689cc004a36768a9d1b79220 1217 SMART SM00388 528 593 3.3E-23 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_12280 6093bca3689cc004a36768a9d1b79220 1217 SMART SM00448 949 1078 6.2E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_12280 6093bca3689cc004a36768a9d1b79220 1217 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 395 515 1.4E-9 T 14-10-2018 IPR000014 PAS domain TSH58p_12280 6093bca3689cc004a36768a9d1b79220 1217 Pfam PF08448 PAS fold 404 510 1.2E-6 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_12280 6093bca3689cc004a36768a9d1b79220 1217 SUPERFAMILY SSF55785 387 506 1.22E-14 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Pfam PF14252 Domain of unknown function (DUF4347) 115 277 2.2E-51 T 14-10-2018 IPR025592 Domain of unknown function DUF4347 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.10 4534 4609 2.6E-10 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.10 4012 4109 9.1E-23 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.10 4111 4209 1.1E-21 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Pfam PF12245 Bacterial Ig-like domain (group 3) 4183 4209 0.067 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Pfam PF12245 Bacterial Ig-like domain (group 3) 4498 4525 0.17 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.2700 1205 1298 1.2E-17 T 14-10-2018 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.2700 1704 1800 1.6E-17 T 14-10-2018 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.2700 1100 1194 2.3E-18 T 14-10-2018 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.2700 3003 3100 3.4E-18 T 14-10-2018 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.2700 1001 1094 1.2E-17 T 14-10-2018 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.2700 896 990 2.1E-18 T 14-10-2018 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.2700 1303 1400 2.6E-18 T 14-10-2018 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.2700 3403 3500 1.1E-17 T 14-10-2018 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.2700 1904 2000 1.6E-17 T 14-10-2018 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.2700 3304 3400 2.0E-17 T 14-10-2018 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.2700 1403 1500 1.1E-17 T 14-10-2018 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.2700 1803 1900 1.1E-17 T 14-10-2018 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.2700 2504 2600 1.6E-17 T 14-10-2018 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.2700 1603 1700 3.5E-17 T 14-10-2018 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.2700 2903 3000 1.1E-17 T 14-10-2018 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.2700 3503 3599 5.3E-18 T 14-10-2018 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.2700 2703 2800 1.1E-17 T 14-10-2018 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.2700 3104 3200 3.8E-18 T 14-10-2018 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.2700 1504 1600 1.6E-17 T 14-10-2018 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.2700 2304 2400 1.6E-17 T 14-10-2018 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.2700 2804 2900 2.6E-17 T 14-10-2018 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.2700 2403 2500 1.1E-17 T 14-10-2018 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.2700 3204 3300 1.6E-17 T 14-10-2018 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.2700 2104 2200 1.6E-17 T 14-10-2018 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.2700 2203 2300 1.1E-17 T 14-10-2018 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.2700 2004 2100 2.6E-17 T 14-10-2018 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.2700 794 890 8.9E-18 T 14-10-2018 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.2700 2604 2700 1.3E-17 T 14-10-2018 TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.10 3908 4011 2.2E-8 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.10 4434 4533 4.6E-18 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 Gene3D G3DSA:2.60.40.10 4334 4433 1.4E-17 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_00910 9f0fb8882c6240a8462599bdfc19747a 4996 SUPERFAMILY SSF51126 279 644 4.59E-18 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor TSH58p_26440 b3d459ef50f322308fbd309438db5ab6 748 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 335 473 3.7E-15 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_26440 b3d459ef50f322308fbd309438db5ab6 748 Gene3D G3DSA:3.30.565.10 285 473 2.7E-47 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_26440 b3d459ef50f322308fbd309438db5ab6 748 Gene3D G3DSA:2.30.30.40 480 602 1.4E-15 T 14-10-2018 TSH58p_26440 b3d459ef50f322308fbd309438db5ab6 748 PRINTS PR00344 Bacterial sensor protein C-terminal signature 458 471 8.7E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_26440 b3d459ef50f322308fbd309438db5ab6 748 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 452 8.7E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_26440 b3d459ef50f322308fbd309438db5ab6 748 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 390 8.7E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_26440 b3d459ef50f322308fbd309438db5ab6 748 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 428 8.7E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_26440 b3d459ef50f322308fbd309438db5ab6 748 Pfam PF00072 Response regulator receiver domain 631 743 7.2E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_26440 b3d459ef50f322308fbd309438db5ab6 748 SUPERFAMILY SSF55874 291 472 1.92E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_26440 b3d459ef50f322308fbd309438db5ab6 748 SMART SM00448 629 744 1.0E-33 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_26440 b3d459ef50f322308fbd309438db5ab6 748 Gene3D G3DSA:2.40.50.180 497 562 1.4E-15 T 14-10-2018 TSH58p_26440 b3d459ef50f322308fbd309438db5ab6 748 Pfam PF01584 CheW-like domain 479 606 7.0E-11 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TSH58p_26440 b3d459ef50f322308fbd309438db5ab6 748 SUPERFAMILY SSF50341 477 606 4.19E-16 T 14-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 TSH58p_26440 b3d459ef50f322308fbd309438db5ab6 748 Pfam PF01627 Hpt domain 8 99 6.1E-11 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TSH58p_26440 b3d459ef50f322308fbd309438db5ab6 748 SUPERFAMILY SSF47226 6 123 1.7E-20 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_26440 b3d459ef50f322308fbd309438db5ab6 748 SMART SM00387 331 474 4.5E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_26440 b3d459ef50f322308fbd309438db5ab6 748 Gene3D G3DSA:3.40.50.12740 629 748 2.0E-37 T 14-10-2018 TSH58p_26440 b3d459ef50f322308fbd309438db5ab6 748 Gene3D G3DSA:1.20.120.160 2 137 3.7E-19 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_26440 b3d459ef50f322308fbd309438db5ab6 748 SMART SM00260 466 607 6.2E-6 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TSH58p_26440 b3d459ef50f322308fbd309438db5ab6 748 SUPERFAMILY SSF52172 625 748 5.69E-34 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_26440 b3d459ef50f322308fbd309438db5ab6 748 SMART SM00073 5 102 1.7E-11 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TSH58p_08275 333abc11f93da20db9d5a7450b75adf7 294 Pfam PF01575 MaoC like domain 169 247 2.4E-5 T 14-10-2018 IPR002539 MaoC-like dehydratase domain TSH58p_08275 333abc11f93da20db9d5a7450b75adf7 294 SUPERFAMILY SSF54637 61 143 3.82E-6 T 14-10-2018 IPR029069 HotDog domain superfamily TSH58p_08275 333abc11f93da20db9d5a7450b75adf7 294 Gene3D G3DSA:3.10.129.10 59 276 6.9E-28 T 14-10-2018 TSH58p_08275 333abc11f93da20db9d5a7450b75adf7 294 SUPERFAMILY SSF54637 167 269 3.97E-13 T 14-10-2018 IPR029069 HotDog domain superfamily TSH58p_28560 ede26895414fe54a5630053f858ad867 652 SUPERFAMILY SSF53756 357 647 6.28E-10 T 14-10-2018 TSH58p_28560 ede26895414fe54a5630053f858ad867 652 Gene3D G3DSA:1.25.40.10 219 274 7.3E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_28560 ede26895414fe54a5630053f858ad867 652 Gene3D G3DSA:1.25.40.10 179 218 1.9E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_28560 ede26895414fe54a5630053f858ad867 652 Gene3D G3DSA:3.40.50.11380 286 638 1.3E-132 T 14-10-2018 TSH58p_28560 ede26895414fe54a5630053f858ad867 652 Pfam PF00515 Tetratricopeptide repeat 210 243 1.4E-7 T 14-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 TSH58p_28560 ede26895414fe54a5630053f858ad867 652 Pfam PF13432 Tetratricopeptide repeat 20 68 5.9E-8 T 14-10-2018 TSH58p_28560 ede26895414fe54a5630053f858ad867 652 Pfam PF13432 Tetratricopeptide repeat 78 140 3.8E-9 T 14-10-2018 TSH58p_28560 ede26895414fe54a5630053f858ad867 652 Pfam PF13432 Tetratricopeptide repeat 147 208 2.3E-7 T 14-10-2018 TSH58p_28560 ede26895414fe54a5630053f858ad867 652 SUPERFAMILY SSF48452 14 257 6.35E-45 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_28560 ede26895414fe54a5630053f858ad867 652 Gene3D G3DSA:1.25.40.10 76 178 1.2E-24 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_28560 ede26895414fe54a5630053f858ad867 652 Gene3D G3DSA:1.25.40.10 14 75 2.8E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_28560 ede26895414fe54a5630053f858ad867 652 Gene3D G3DSA:3.40.50.2000 449 631 1.3E-132 T 14-10-2018 TSH58p_28560 ede26895414fe54a5630053f858ad867 652 Pfam PF13844 Glycosyl transferase family 41 295 440 4.9E-29 T 14-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 TSH58p_28560 ede26895414fe54a5630053f858ad867 652 Pfam PF13844 Glycosyl transferase family 41 467 649 5.7E-19 T 14-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 TSH58p_28560 ede26895414fe54a5630053f858ad867 652 SMART SM00028 7 40 46.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_28560 ede26895414fe54a5630053f858ad867 652 SMART SM00028 176 209 0.019 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_28560 ede26895414fe54a5630053f858ad867 652 SMART SM00028 210 243 2.4E-6 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_28560 ede26895414fe54a5630053f858ad867 652 SMART SM00028 108 141 4.5E-5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_28560 ede26895414fe54a5630053f858ad867 652 SMART SM00028 41 74 10.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_28560 ede26895414fe54a5630053f858ad867 652 SMART SM00028 75 107 29.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_28560 ede26895414fe54a5630053f858ad867 652 SMART SM00028 142 175 0.0022 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_09535 6b47266d840ed1b248187388615cbc92 417 Gene3D G3DSA:3.40.50.300 212 401 9.7E-110 T 14-10-2018 TSH58p_09535 6b47266d840ed1b248187388615cbc92 417 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 141 413 59.234 T 14-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 TSH58p_09535 6b47266d840ed1b248187388615cbc92 417 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 141 411 7.6E-100 T 14-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 TSH58p_09535 6b47266d840ed1b248187388615cbc92 417 SUPERFAMILY SSF47364 113 190 4.97E-20 T 14-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 TSH58p_09535 6b47266d840ed1b248187388615cbc92 417 Pfam PF02881 SRP54-type protein, helical bundle domain 129 190 1.8E-9 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSH58p_09535 6b47266d840ed1b248187388615cbc92 417 SMART SM00963 118 197 8.4E-18 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSH58p_09535 6b47266d840ed1b248187388615cbc92 417 Pfam PF00448 SRP54-type protein, GTPase domain 212 412 3.5E-72 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSH58p_09535 6b47266d840ed1b248187388615cbc92 417 SMART SM00382 211 391 4.1E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_09535 6b47266d840ed1b248187388615cbc92 417 SMART SM00962 212 413 1.9E-113 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSH58p_09535 6b47266d840ed1b248187388615cbc92 417 Gene3D G3DSA:1.20.120.140 115 411 9.7E-110 T 14-10-2018 TSH58p_09535 6b47266d840ed1b248187388615cbc92 417 SUPERFAMILY SSF52540 211 413 7.8E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_01405 97182ed5fdf320081d8eaafca4bbcd38 324 Gene3D G3DSA:3.40.50.970 3 194 9.5E-82 T 14-10-2018 TSH58p_01405 97182ed5fdf320081d8eaafca4bbcd38 324 SUPERFAMILY SSF52922 189 323 1.07E-39 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSH58p_01405 97182ed5fdf320081d8eaafca4bbcd38 324 SMART SM00861 5 180 3.6E-62 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSH58p_01405 97182ed5fdf320081d8eaafca4bbcd38 324 Pfam PF02779 Transketolase, pyrimidine binding domain 5 179 9.6E-50 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSH58p_01405 97182ed5fdf320081d8eaafca4bbcd38 324 SUPERFAMILY SSF52518 4 183 3.14E-66 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_01405 97182ed5fdf320081d8eaafca4bbcd38 324 Gene3D G3DSA:3.40.50.920 195 324 4.8E-46 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSH58p_01405 97182ed5fdf320081d8eaafca4bbcd38 324 Pfam PF02780 Transketolase, C-terminal domain 193 315 9.7E-40 T 14-10-2018 IPR033248 Transketolase, C-terminal domain TSH58p_12405 b115979da79b86e3a5a12907d796b601 687 Pfam PF06761 Intracellular multiplication and human macrophage-killing 524 672 6.4E-30 T 14-10-2018 IPR009612 ImcF-related TSH58p_12405 b115979da79b86e3a5a12907d796b601 687 TIGRFAM TIGR03348 VI_IcmF: type VI secretion protein IcmF 64 672 3.4E-167 T 14-10-2018 IPR017731 Type VI secretion system, IcmF TSH58p_12405 b115979da79b86e3a5a12907d796b601 687 SUPERFAMILY SSF52540 156 329 2.45E-12 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_12405 b115979da79b86e3a5a12907d796b601 687 Pfam PF14331 ImcF-related N-terminal domain 231 463 1.7E-74 T 14-10-2018 IPR025743 ImcF-related, N-terminal domain TSH58p_26210 a26a41fd36836502ff53b7008b962fbd 712 Pfam PF00122 E1-E2 ATPase 199 361 4.6E-33 T 14-10-2018 TSH58p_26210 a26a41fd36836502ff53b7008b962fbd 712 SUPERFAMILY SSF81653 200 296 1.83E-25 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 TSH58p_26210 a26a41fd36836502ff53b7008b962fbd 712 Gene3D G3DSA:3.40.50.1000 369 639 2.2E-76 T 14-10-2018 IPR023214 HAD superfamily TSH58p_26210 a26a41fd36836502ff53b7008b962fbd 712 SUPERFAMILY SSF56784 386 690 1.78E-39 T 14-10-2018 IPR036412 HAD-like superfamily TSH58p_26210 a26a41fd36836502ff53b7008b962fbd 712 Gene3D G3DSA:2.70.150.20 190 300 9.1E-30 T 14-10-2018 TSH58p_26210 a26a41fd36836502ff53b7008b962fbd 712 Pfam PF00702 haloacid dehalogenase-like hydrolase 385 603 1.3E-28 T 14-10-2018 TSH58p_26210 a26a41fd36836502ff53b7008b962fbd 712 ProSitePatterns PS01229 Hypothetical cof family signature 2. 590 612 - T 14-10-2018 TSH58p_26210 a26a41fd36836502ff53b7008b962fbd 712 Gene3D G3DSA:3.40.1110.10 399 521 2.2E-76 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TSH58p_26210 a26a41fd36836502ff53b7008b962fbd 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 514 525 4.2E-24 T 14-10-2018 TSH58p_26210 a26a41fd36836502ff53b7008b962fbd 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 613 625 4.2E-24 T 14-10-2018 TSH58p_26210 a26a41fd36836502ff53b7008b962fbd 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 590 609 4.2E-24 T 14-10-2018 TSH58p_26210 a26a41fd36836502ff53b7008b962fbd 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 246 260 4.2E-24 T 14-10-2018 TSH58p_26210 a26a41fd36836502ff53b7008b962fbd 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 537 547 4.2E-24 T 14-10-2018 TSH58p_26210 a26a41fd36836502ff53b7008b962fbd 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 388 402 4.2E-24 T 14-10-2018 TSH58p_26210 a26a41fd36836502ff53b7008b962fbd 712 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 147 691 2.3E-139 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TSH58p_26210 a26a41fd36836502ff53b7008b962fbd 712 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 169 666 3.3E-66 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TSH58p_26210 a26a41fd36836502ff53b7008b962fbd 712 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 390 396 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 TSH58p_21020 e9c938353c55b50007104c3ee1194454 759 Gene3D G3DSA:1.10.287.130 502 593 8.4E-16 T 14-10-2018 TSH58p_21020 e9c938353c55b50007104c3ee1194454 759 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 636 746 1.1E-14 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_21020 e9c938353c55b50007104c3ee1194454 759 Gene3D G3DSA:3.30.450.270 327 501 4.1E-163 T 14-10-2018 TSH58p_21020 e9c938353c55b50007104c3ee1194454 759 Gene3D G3DSA:3.30.565.10 600 751 2.2E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_21020 e9c938353c55b50007104c3ee1194454 759 SMART SM00065 152 331 1.1E-5 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_21020 e9c938353c55b50007104c3ee1194454 759 Gene3D G3DSA:3.30.450.20 15 258 4.1E-163 T 14-10-2018 TSH58p_21020 e9c938353c55b50007104c3ee1194454 759 SUPERFAMILY SSF55781 140 319 9.25E-55 T 14-10-2018 TSH58p_21020 e9c938353c55b50007104c3ee1194454 759 Pfam PF00512 His Kinase A (phospho-acceptor) domain 529 593 2.8E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_21020 e9c938353c55b50007104c3ee1194454 759 Pfam PF01590 GAF domain 156 318 1.3E-14 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_21020 e9c938353c55b50007104c3ee1194454 759 SUPERFAMILY SSF55781 329 513 6.47E-56 T 14-10-2018 TSH58p_21020 e9c938353c55b50007104c3ee1194454 759 Pfam PF08446 PAS fold 11 92 3.4E-11 T 14-10-2018 IPR013654 PAS fold-2 GO:0006355 TSH58p_21020 e9c938353c55b50007104c3ee1194454 759 SUPERFAMILY SSF55785 2 124 6.8E-22 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_21020 e9c938353c55b50007104c3ee1194454 759 PRINTS PR01033 Phytochrome signature 470 488 2.0E-8 T 14-10-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 TSH58p_21020 e9c938353c55b50007104c3ee1194454 759 PRINTS PR01033 Phytochrome signature 47 69 2.0E-8 T 14-10-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 TSH58p_21020 e9c938353c55b50007104c3ee1194454 759 PRINTS PR01033 Phytochrome signature 438 457 2.0E-8 T 14-10-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 TSH58p_21020 e9c938353c55b50007104c3ee1194454 759 PRINTS PR01033 Phytochrome signature 353 373 2.0E-8 T 14-10-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 TSH58p_21020 e9c938353c55b50007104c3ee1194454 759 SMART SM00388 527 595 1.5E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_21020 e9c938353c55b50007104c3ee1194454 759 SMART SM00387 636 748 5.3E-25 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_21020 e9c938353c55b50007104c3ee1194454 759 SUPERFAMILY SSF47384 512 594 1.18E-15 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_21020 e9c938353c55b50007104c3ee1194454 759 Pfam PF00360 Phytochrome region 334 511 1.4E-59 T 14-10-2018 IPR013515 Phytochrome, central region GO:0006355|GO:0009584|GO:0018298 TSH58p_21020 e9c938353c55b50007104c3ee1194454 759 Gene3D G3DSA:3.30.450.40 11 483 4.1E-163 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_21020 e9c938353c55b50007104c3ee1194454 759 SUPERFAMILY SSF55874 594 748 2.62E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_22060 37cfa290352a4407783002d08fce0d7e 145 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 102 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site TSH58p_22060 37cfa290352a4407783002d08fce0d7e 145 Gene3D G3DSA:1.10.10.10 1 140 5.8E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_22060 37cfa290352a4407783002d08fce0d7e 145 Pfam PF12802 MarR family 33 92 1.8E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_22060 37cfa290352a4407783002d08fce0d7e 145 SUPERFAMILY SSF46785 13 140 7.14E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_22060 37cfa290352a4407783002d08fce0d7e 145 SMART SM00347 27 126 1.5E-4 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_28650 4cfa3027f736ad688c1cdf20064149e8 267 Gene3D G3DSA:1.10.12.10 211 265 1.3E-12 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal TSH58p_28650 4cfa3027f736ad688c1cdf20064149e8 267 SUPERFAMILY SSF52096 14 265 1.61E-70 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_28650 4cfa3027f736ad688c1cdf20064149e8 267 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 109 129 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 TSH58p_28650 4cfa3027f736ad688c1cdf20064149e8 267 Gene3D G3DSA:3.90.226.10 11 209 3.0E-58 T 14-10-2018 TSH58p_28650 4cfa3027f736ad688c1cdf20064149e8 267 Pfam PF00378 Enoyl-CoA hydratase/isomerase 19 264 9.7E-48 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TSH58p_31830 c54a7dcf5f4761c1e542dc205ba36b20 1927 Pfam PF13191 AAA ATPase domain 307 495 7.9E-41 T 14-10-2018 TSH58p_31830 c54a7dcf5f4761c1e542dc205ba36b20 1927 SMART SM00388 1681 1765 0.0083 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_31830 c54a7dcf5f4761c1e542dc205ba36b20 1927 Pfam PF01590 GAF domain 1367 1508 1.3E-14 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_31830 c54a7dcf5f4761c1e542dc205ba36b20 1927 SUPERFAMILY SSF55781 1350 1529 2.18E-27 T 14-10-2018 TSH58p_31830 c54a7dcf5f4761c1e542dc205ba36b20 1927 Gene3D G3DSA:3.30.565.10 1758 1918 7.1E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_31830 c54a7dcf5f4761c1e542dc205ba36b20 1927 Pfam PF12860 PAS fold 1546 1649 5.1E-20 T 14-10-2018 TSH58p_31830 c54a7dcf5f4761c1e542dc205ba36b20 1927 SUPERFAMILY SSF47384 1675 1753 7.06E-6 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_31830 c54a7dcf5f4761c1e542dc205ba36b20 1927 Gene3D G3DSA:1.10.510.10 107 284 2.6E-36 T 14-10-2018 TSH58p_31830 c54a7dcf5f4761c1e542dc205ba36b20 1927 Pfam PF00069 Protein kinase domain 18 266 2.1E-32 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TSH58p_31830 c54a7dcf5f4761c1e542dc205ba36b20 1927 SMART SM00387 1807 1920 5.3E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_31830 c54a7dcf5f4761c1e542dc205ba36b20 1927 Pfam PF00512 His Kinase A (phospho-acceptor) domain 1681 1762 1.4E-6 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_31830 c54a7dcf5f4761c1e542dc205ba36b20 1927 Gene3D G3DSA:3.30.450.20 1528 1646 9.2E-9 T 14-10-2018 TSH58p_31830 c54a7dcf5f4761c1e542dc205ba36b20 1927 SUPERFAMILY SSF55874 1757 1918 2.49E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_31830 c54a7dcf5f4761c1e542dc205ba36b20 1927 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1866 1876 1.8E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_31830 c54a7dcf5f4761c1e542dc205ba36b20 1927 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1848 1862 1.8E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_31830 c54a7dcf5f4761c1e542dc205ba36b20 1927 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1879 1897 1.8E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_31830 c54a7dcf5f4761c1e542dc205ba36b20 1927 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1904 1917 1.8E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_31830 c54a7dcf5f4761c1e542dc205ba36b20 1927 SUPERFAMILY SSF56112 13 277 3.51E-51 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily TSH58p_31830 c54a7dcf5f4761c1e542dc205ba36b20 1927 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1812 1918 1.3E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_31830 c54a7dcf5f4761c1e542dc205ba36b20 1927 Gene3D G3DSA:1.10.287.130 1658 1757 1.2E-22 T 14-10-2018 TSH58p_31830 c54a7dcf5f4761c1e542dc205ba36b20 1927 SMART SM00065 1364 1518 6.2E-19 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_31830 c54a7dcf5f4761c1e542dc205ba36b20 1927 Gene3D G3DSA:3.30.200.20 14 93 8.2E-7 T 14-10-2018 TSH58p_31830 c54a7dcf5f4761c1e542dc205ba36b20 1927 Gene3D G3DSA:3.30.450.40 1346 1521 1.6E-32 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_31830 c54a7dcf5f4761c1e542dc205ba36b20 1927 SUPERFAMILY SSF52540 304 577 2.73E-11 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_15485 db80f25428c8108bf9411425d51eb055 134 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 9 131 3.5E-22 T 14-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 TSH58p_15485 db80f25428c8108bf9411425d51eb055 134 PIRSF PIRSF002889 1 133 8.3E-23 T 14-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 TSH58p_15485 db80f25428c8108bf9411425d51eb055 134 Pfam PF00460 Flagella basal body rod protein 22 39 8.1E-7 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 TSH58p_26380 04efaaea3b689af66451c741b5fc746f 247 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 16 195 1.1E-45 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal TSH58p_26380 04efaaea3b689af66451c741b5fc746f 247 SUPERFAMILY SSF53639 7 219 1.53E-61 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TSH58p_26380 04efaaea3b689af66451c741b5fc746f 247 SMART SM01007 15 195 6.8E-58 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal TSH58p_26380 04efaaea3b689af66451c741b5fc746f 247 Gene3D G3DSA:3.40.225.10 4 247 1.7E-78 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TSH58p_13535 ad3a1f47c362073c1c9d4b956cee2789 619 SUPERFAMILY SSF48019 267 393 4.85E-28 T 14-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 TSH58p_13535 ad3a1f47c362073c1c9d4b956cee2789 619 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 22 382 8.9E-127 T 14-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 TSH58p_13535 ad3a1f47c362073c1c9d4b956cee2789 619 Pfam PF12362 DNA polymerase III gamma and tau subunits C terminal 465 578 1.7E-38 T 14-10-2018 IPR022107 DNA polymerase III, subunit gamma/ tau, C-terminal TSH58p_13535 ad3a1f47c362073c1c9d4b956cee2789 619 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 256 397 2.1E-51 T 14-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 TSH58p_13535 ad3a1f47c362073c1c9d4b956cee2789 619 Pfam PF13177 DNA polymerase III, delta subunit 39 202 2.4E-37 T 14-10-2018 TSH58p_13535 ad3a1f47c362073c1c9d4b956cee2789 619 Gene3D G3DSA:1.20.272.10 266 385 1.3E-14 T 14-10-2018 TSH58p_13535 ad3a1f47c362073c1c9d4b956cee2789 619 SUPERFAMILY SSF52540 22 265 8.75E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_13535 ad3a1f47c362073c1c9d4b956cee2789 619 SMART SM00382 56 203 1.6E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_13535 ad3a1f47c362073c1c9d4b956cee2789 619 Gene3D G3DSA:3.40.50.300 32 201 2.1E-102 T 14-10-2018 TSH58p_13535 ad3a1f47c362073c1c9d4b956cee2789 619 Gene3D G3DSA:1.10.8.60 27 264 2.1E-102 T 14-10-2018 TSH58p_29765 67d2fe41b2abab1b5dcd479779dfb0a7 843 SUPERFAMILY SSF56059 32 466 9.89E-25 T 14-10-2018 TSH58p_29765 67d2fe41b2abab1b5dcd479779dfb0a7 843 Gene3D G3DSA:3.40.50.11290 227 323 3.8E-43 T 14-10-2018 TSH58p_29765 67d2fe41b2abab1b5dcd479779dfb0a7 843 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 518 835 8.4E-72 T 14-10-2018 IPR007296 Domain of unknown function DUF403 TSH58p_29765 67d2fe41b2abab1b5dcd479779dfb0a7 843 Pfam PF14403 Circularly permuted ATP-grasp type 2 89 465 6.1E-157 T 14-10-2018 IPR025841 Circularly permuted ATP-grasp type 2 TSH58p_29765 67d2fe41b2abab1b5dcd479779dfb0a7 843 Gene3D G3DSA:3.30.1490.270 360 419 8.1E-7 T 14-10-2018 TSH58p_16770 c6c8bce3bec8addda212cf147b570d69 293 Pfam PF02219 Methylenetetrahydrofolate reductase 3 284 7.4E-98 T 14-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 TSH58p_16770 c6c8bce3bec8addda212cf147b570d69 293 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 8 283 1.6E-106 T 14-10-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 TSH58p_16770 c6c8bce3bec8addda212cf147b570d69 293 SUPERFAMILY SSF51730 3 285 4.32E-99 T 14-10-2018 IPR029041 FAD-linked oxidoreductase-like TSH58p_16770 c6c8bce3bec8addda212cf147b570d69 293 Gene3D G3DSA:3.20.20.220 1 292 1.1E-107 T 14-10-2018 TSH58p_25220 16c40a65813cce4f49fa5f0ff2779542 933 Pfam PF16841 Ca-dependent carbohydrate-binding module xylan-binding 12 104 8.3E-31 T 14-10-2018 IPR031768 Carbohydrate binding module, xylan-binding domain MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSH58p_25220 16c40a65813cce4f49fa5f0ff2779542 933 Pfam PF16841 Ca-dependent carbohydrate-binding module xylan-binding 147 238 6.2E-29 T 14-10-2018 IPR031768 Carbohydrate binding module, xylan-binding domain MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSH58p_25220 16c40a65813cce4f49fa5f0ff2779542 933 Gene3D G3DSA:2.60.60.40 10 124 3.5E-7 T 14-10-2018 TSH58p_25220 16c40a65813cce4f49fa5f0ff2779542 933 Gene3D G3DSA:2.60.60.40 145 259 2.4E-8 T 14-10-2018 TSH58p_25220 16c40a65813cce4f49fa5f0ff2779542 933 Pfam PF13229 Right handed beta helix region 737 854 2.9E-10 T 14-10-2018 IPR039448 Right handed beta helix domain TSH58p_25220 16c40a65813cce4f49fa5f0ff2779542 933 Pfam PF13229 Right handed beta helix region 556 718 1.6E-16 T 14-10-2018 IPR039448 Right handed beta helix domain TSH58p_25220 16c40a65813cce4f49fa5f0ff2779542 933 SMART SM00710 606 628 39.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_25220 16c40a65813cce4f49fa5f0ff2779542 933 SMART SM00710 822 844 1000.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_25220 16c40a65813cce4f49fa5f0ff2779542 933 SMART SM00710 584 605 0.28 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_25220 16c40a65813cce4f49fa5f0ff2779542 933 SMART SM00710 658 680 110.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_25220 16c40a65813cce4f49fa5f0ff2779542 933 SMART SM00710 688 715 260.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_25220 16c40a65813cce4f49fa5f0ff2779542 933 SMART SM00710 788 816 4600.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_25220 16c40a65813cce4f49fa5f0ff2779542 933 SMART SM00710 630 657 2100.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_25220 16c40a65813cce4f49fa5f0ff2779542 933 SMART SM00710 559 583 650.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_25220 16c40a65813cce4f49fa5f0ff2779542 933 SMART SM00710 766 787 3.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_25220 16c40a65813cce4f49fa5f0ff2779542 933 Gene3D G3DSA:2.160.20.10 753 865 1.3E-7 T 14-10-2018 IPR012334 Pectin lyase fold TSH58p_25220 16c40a65813cce4f49fa5f0ff2779542 933 Gene3D G3DSA:2.160.20.10 286 403 1.3E-11 T 14-10-2018 IPR012334 Pectin lyase fold TSH58p_25220 16c40a65813cce4f49fa5f0ff2779542 933 SUPERFAMILY SSF51126 323 875 8.93E-35 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor TSH58p_25220 16c40a65813cce4f49fa5f0ff2779542 933 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 759 801 1.5E-7 T 14-10-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 TSH58p_25220 16c40a65813cce4f49fa5f0ff2779542 933 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 579 616 3.7E-6 T 14-10-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 TSH58p_25220 16c40a65813cce4f49fa5f0ff2779542 933 Gene3D G3DSA:2.160.20.10 482 748 3.0E-16 T 14-10-2018 IPR012334 Pectin lyase fold TSH58p_25645 1c894b9f98483ad5677788d8ac11d5dc 306 SUPERFAMILY SSF53850 90 297 1.32E-45 T 14-10-2018 TSH58p_25645 1c894b9f98483ad5677788d8ac11d5dc 306 Pfam PF03466 LysR substrate binding domain 88 293 7.0E-46 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_25645 1c894b9f98483ad5677788d8ac11d5dc 306 Gene3D G3DSA:3.40.190.10 163 264 3.6E-66 T 14-10-2018 TSH58p_25645 1c894b9f98483ad5677788d8ac11d5dc 306 Gene3D G3DSA:3.40.190.10 92 291 3.6E-66 T 14-10-2018 TSH58p_25645 1c894b9f98483ad5677788d8ac11d5dc 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 3.8E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_25645 1c894b9f98483ad5677788d8ac11d5dc 306 SUPERFAMILY SSF46785 5 86 4.42E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_25645 1c894b9f98483ad5677788d8ac11d5dc 306 Gene3D G3DSA:1.10.10.10 3 86 1.7E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_25590 1d1aa9b241afbd17365cec00b0e1fbd7 698 Gene3D G3DSA:3.80.30.20 347 601 2.7E-16 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TSH58p_25590 1d1aa9b241afbd17365cec00b0e1fbd7 698 SMART SM00729 348 604 4.4E-11 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSH58p_25590 1d1aa9b241afbd17365cec00b0e1fbd7 698 TIGRFAM TIGR03904 SAM_YgiQ: uncharacterized radical SAM protein YgiQ 33 617 2.5E-261 T 14-10-2018 IPR022946 Uncharacterised protein family UPF0313 TSH58p_25590 1d1aa9b241afbd17365cec00b0e1fbd7 698 Hamap MF_01251 UPF0313 protein YgiQ [ygiQ]. 33 619 48.862 T 14-10-2018 IPR022946 Uncharacterised protein family UPF0313 TSH58p_25590 1d1aa9b241afbd17365cec00b0e1fbd7 698 Pfam PF04055 Radical SAM superfamily 352 557 2.4E-22 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSH58p_25590 1d1aa9b241afbd17365cec00b0e1fbd7 698 Pfam PF08497 Radical SAM N-terminal 33 351 1.0E-143 T 14-10-2018 IPR013704 Uncharacterised protein family UPF0313, N-terminal TSH58p_25590 1d1aa9b241afbd17365cec00b0e1fbd7 698 SUPERFAMILY SSF102114 349 585 3.14E-14 T 14-10-2018 TSH58p_25590 1d1aa9b241afbd17365cec00b0e1fbd7 698 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 352 372 - T 14-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 TSH58p_25590 1d1aa9b241afbd17365cec00b0e1fbd7 698 Pfam PF11842 Domain of unknown function (DUF3362) 566 670 9.7E-42 T 14-10-2018 IPR024560 Uncharacterised protein family UPF0313, C-terminal TSH58p_28985 9289c0f9e9a86ae00e579ec23dfba349 340 SUPERFAMILY SSF53850 34 270 3.15E-29 T 14-10-2018 TSH58p_28985 9289c0f9e9a86ae00e579ec23dfba349 340 Pfam PF13379 NMT1-like family 31 274 5.4E-28 T 14-10-2018 TSH58p_28985 9289c0f9e9a86ae00e579ec23dfba349 340 Gene3D G3DSA:3.40.190.10 30 142 9.7E-12 T 14-10-2018 TSH58p_28985 9289c0f9e9a86ae00e579ec23dfba349 340 Gene3D G3DSA:3.40.190.10 152 334 1.2E-17 T 14-10-2018 TSH58p_21710 c19c95f964ede8c616d397b8171d5dc4 641 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 449 602 7.1E-30 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_21710 c19c95f964ede8c616d397b8171d5dc4 641 SMART SM00304 293 345 0.0021 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_21710 c19c95f964ede8c616d397b8171d5dc4 641 SMART SM00283 382 636 7.7E-33 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_21710 c19c95f964ede8c616d397b8171d5dc4 641 Gene3D G3DSA:1.10.287.950 294 637 7.2E-48 T 14-10-2018 TSH58p_21710 c19c95f964ede8c616d397b8171d5dc4 641 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 509 538 5.5E-18 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_21710 c19c95f964ede8c616d397b8171d5dc4 641 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 399 428 5.5E-18 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_21710 c19c95f964ede8c616d397b8171d5dc4 641 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 480 507 5.5E-18 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_21710 c19c95f964ede8c616d397b8171d5dc4 641 SUPERFAMILY SSF58104 360 635 7.98E-54 T 14-10-2018 TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 SUPERFAMILY SSF55874 530 683 1.7E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 SMART SM00387 571 684 2.7E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 47 163 1.2E-5 T 14-10-2018 IPR000014 PAS domain TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 298 415 6.6E-11 T 14-10-2018 IPR000014 PAS domain TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 193 293 8.4E-15 T 14-10-2018 IPR000014 PAS domain TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 Gene3D G3DSA:3.30.450.20 49 161 4.1E-12 T 14-10-2018 TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 SUPERFAMILY SSF55785 47 157 9.42E-12 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 SMART SM00091 171 238 1.4E-4 T 14-10-2018 IPR000014 PAS domain TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 SMART SM00091 49 116 6.4 T 14-10-2018 IPR000014 PAS domain TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 SMART SM00091 299 366 9.0E-4 T 14-10-2018 IPR000014 PAS domain TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 SUPERFAMILY SSF47384 440 503 4.32E-5 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 Pfam PF08447 PAS fold 195 281 2.8E-21 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 SUPERFAMILY SSF55785 284 406 2.09E-19 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 SUPERFAMILY SSF55785 177 289 9.42E-25 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 PRINTS PR00344 Bacterial sensor protein C-terminal signature 612 626 9.6E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 PRINTS PR00344 Bacterial sensor protein C-terminal signature 643 661 9.6E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 PRINTS PR00344 Bacterial sensor protein C-terminal signature 668 681 9.6E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 PRINTS PR00344 Bacterial sensor protein C-terminal signature 630 640 9.6E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 SMART SM00086 245 287 6.2E-12 T 14-10-2018 IPR001610 PAC motif TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 SMART SM00086 369 409 0.013 T 14-10-2018 IPR001610 PAC motif TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 574 682 2.5E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 Gene3D G3DSA:3.30.565.10 529 687 2.5E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 Pfam PF13426 PAS domain 60 158 0.0019 T 14-10-2018 IPR000014 PAS domain TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 Gene3D G3DSA:3.30.450.20 288 406 2.4E-19 T 14-10-2018 TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 Pfam PF00512 His Kinase A (phospho-acceptor) domain 445 520 7.9E-7 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 Gene3D G3DSA:1.10.287.130 421 523 1.6E-19 T 14-10-2018 TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 Gene3D G3DSA:2.10.70.100 242 287 2.5E-14 T 14-10-2018 TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 Pfam PF00989 PAS fold 300 390 3.2E-7 T 14-10-2018 IPR013767 PAS fold GO:0006355 TSH58p_28955 a5ac1c90a7a07d7c62ad505dd09701a4 704 Gene3D G3DSA:3.30.450.20 170 239 3.2E-15 T 14-10-2018 TSH58p_22140 7b196fd345a79e45c736edf089d070e8 182 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 7 163 4.8E-56 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TSH58p_22140 7b196fd345a79e45c736edf089d070e8 182 Gene3D G3DSA:3.40.50.620 2 170 4.4E-52 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_22140 7b196fd345a79e45c736edf089d070e8 182 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 6 59 1.1E-18 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TSH58p_22140 7b196fd345a79e45c736edf089d070e8 182 SUPERFAMILY SSF52374 4 162 4.02E-40 T 14-10-2018 TSH58p_22140 7b196fd345a79e45c736edf089d070e8 182 Pfam PF01467 Cytidylyltransferase-like 8 138 4.0E-17 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TSH58p_22140 7b196fd345a79e45c736edf089d070e8 182 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 119 141 1.0E-34 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TSH58p_22140 7b196fd345a79e45c736edf089d070e8 182 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 23 44 1.0E-34 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TSH58p_22140 7b196fd345a79e45c736edf089d070e8 182 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 5 23 1.0E-34 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TSH58p_22140 7b196fd345a79e45c736edf089d070e8 182 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 92 108 1.0E-34 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TSH58p_22140 7b196fd345a79e45c736edf089d070e8 182 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 5 165 33.499 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TSH58p_20325 e1053389e55ed72305ea5307f2bbf070 278 PIRSF PIRSF006625 3 278 6.6E-134 T 14-10-2018 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 TSH58p_20325 e1053389e55ed72305ea5307f2bbf070 278 Pfam PF04962 KduI/IolB family 39 270 2.5E-35 T 14-10-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 TSH58p_20325 e1053389e55ed72305ea5307f2bbf070 278 Hamap MF_00687 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase [kduI]. 3 278 54.867 T 14-10-2018 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 TSH58p_20325 e1053389e55ed72305ea5307f2bbf070 278 Gene3D G3DSA:2.60.120.10 12 264 4.3E-116 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_20325 e1053389e55ed72305ea5307f2bbf070 278 SUPERFAMILY SSF51182 4 262 1.54E-106 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_20325 e1053389e55ed72305ea5307f2bbf070 278 Gene3D G3DSA:2.60.120.520 32 144 4.3E-116 T 14-10-2018 IPR027449 5-keto-4-deoxyuronate isomerase, N-terminal KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 TSH58p_19005 183186616c551bf9d6bdc3aef273f1ab 278 Gene3D G3DSA:1.10.10.10 1 76 5.2E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_19005 183186616c551bf9d6bdc3aef273f1ab 278 SUPERFAMILY SSF53697 93 268 1.3E-39 T 14-10-2018 TSH58p_19005 183186616c551bf9d6bdc3aef273f1ab 278 ProSitePatterns PS00356 LacI-type HTH domain signature. 35 53 - T 14-10-2018 TSH58p_19005 183186616c551bf9d6bdc3aef273f1ab 278 Pfam PF01380 SIS domain 122 243 2.4E-18 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TSH58p_19005 183186616c551bf9d6bdc3aef273f1ab 278 Gene3D G3DSA:3.40.50.10490 90 273 2.3E-43 T 14-10-2018 TSH58p_19005 183186616c551bf9d6bdc3aef273f1ab 278 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 74 2.8E-22 T 14-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 TSH58p_19005 183186616c551bf9d6bdc3aef273f1ab 278 SUPERFAMILY SSF46689 2 76 3.23E-20 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_06910 6b6a5fcba2c6e69e5899d9f87d7e3dab 361 Pfam PF00365 Phosphofructokinase 6 311 2.8E-97 T 14-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TSH58p_06910 6b6a5fcba2c6e69e5899d9f87d7e3dab 361 Gene3D G3DSA:3.40.50.450 7 336 2.7E-99 T 14-10-2018 TSH58p_06910 6b6a5fcba2c6e69e5899d9f87d7e3dab 361 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 5 360 40.654 T 14-10-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 TSH58p_06910 6b6a5fcba2c6e69e5899d9f87d7e3dab 361 Gene3D G3DSA:3.40.50.460 156 291 2.7E-99 T 14-10-2018 TSH58p_06910 6b6a5fcba2c6e69e5899d9f87d7e3dab 361 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 9 28 1.9E-68 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TSH58p_06910 6b6a5fcba2c6e69e5899d9f87d7e3dab 361 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 174 190 1.9E-68 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TSH58p_06910 6b6a5fcba2c6e69e5899d9f87d7e3dab 361 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 192 209 1.9E-68 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TSH58p_06910 6b6a5fcba2c6e69e5899d9f87d7e3dab 361 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 35 48 1.9E-68 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TSH58p_06910 6b6a5fcba2c6e69e5899d9f87d7e3dab 361 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 275 297 1.9E-68 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TSH58p_06910 6b6a5fcba2c6e69e5899d9f87d7e3dab 361 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 136 153 1.9E-68 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TSH58p_06910 6b6a5fcba2c6e69e5899d9f87d7e3dab 361 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 154 172 1.9E-68 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TSH58p_06910 6b6a5fcba2c6e69e5899d9f87d7e3dab 361 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 108 124 1.9E-68 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TSH58p_06910 6b6a5fcba2c6e69e5899d9f87d7e3dab 361 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 228 240 1.9E-68 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TSH58p_06910 6b6a5fcba2c6e69e5899d9f87d7e3dab 361 SUPERFAMILY SSF53784 4 352 5.36E-103 T 14-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TSH58p_06910 6b6a5fcba2c6e69e5899d9f87d7e3dab 361 PIRSF PIRSF000532 3 361 1.1E-120 T 14-10-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 TSH58p_12530 5783de19c1c824fc94c01f89d556e3a9 87 SUPERFAMILY SSF52833 1 84 1.25E-29 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_12530 5783de19c1c824fc94c01f89d556e3a9 87 Gene3D G3DSA:3.40.30.10 1 84 1.4E-29 T 14-10-2018 TSH58p_12530 5783de19c1c824fc94c01f89d556e3a9 87 ProSitePatterns PS00195 Glutaredoxin active site. 6 22 - T 14-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 TSH58p_12530 5783de19c1c824fc94c01f89d556e3a9 87 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 4 83 1.9E-33 T 14-10-2018 IPR011900 Glutaredoxin, GrxC GO:0045454 TSH58p_12530 5783de19c1c824fc94c01f89d556e3a9 87 Pfam PF00462 Glutaredoxin 4 62 1.2E-24 T 14-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 TSH58p_12530 5783de19c1c824fc94c01f89d556e3a9 87 PRINTS PR00160 Glutaredoxin signature 61 74 1.7E-14 T 14-10-2018 IPR014025 Glutaredoxin subgroup TSH58p_12530 5783de19c1c824fc94c01f89d556e3a9 87 PRINTS PR00160 Glutaredoxin signature 4 22 1.7E-14 T 14-10-2018 IPR014025 Glutaredoxin subgroup TSH58p_12530 5783de19c1c824fc94c01f89d556e3a9 87 PRINTS PR00160 Glutaredoxin signature 47 60 1.7E-14 T 14-10-2018 IPR014025 Glutaredoxin subgroup TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 SUPERFAMILY SSF55785 119 246 2.79E-32 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 Pfam PF13426 PAS domain 271 375 2.5E-7 T 14-10-2018 IPR000014 PAS domain TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 SUPERFAMILY SSF47384 383 466 2.16E-18 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 Pfam PF00512 His Kinase A (phospho-acceptor) domain 396 465 6.0E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 Gene3D G3DSA:3.30.565.10 464 623 8.1E-45 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 Gene3D G3DSA:3.30.450.20 257 375 1.3E-25 T 14-10-2018 TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 SUPERFAMILY SSF55874 454 621 1.15E-45 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 130 254 6.1E-19 T 14-10-2018 IPR000014 PAS domain TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 259 382 2.4E-16 T 14-10-2018 IPR000014 PAS domain TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 9 129 8.5E-13 T 14-10-2018 IPR000014 PAS domain TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 Pfam PF08448 PAS fold 142 248 1.7E-19 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 Pfam PF08448 PAS fold 13 123 6.3E-9 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 SUPERFAMILY SSF55785 271 383 2.23E-20 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 SMART SM00091 6 72 3.0E-7 T 14-10-2018 IPR000014 PAS domain TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 SMART SM00091 134 200 7.1E-11 T 14-10-2018 IPR000014 PAS domain TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 SMART SM00091 260 325 0.49 T 14-10-2018 IPR000014 PAS domain TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 511 622 2.4E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 SMART SM00388 396 465 3.0E-17 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 PRINTS PR00344 Bacterial sensor protein C-terminal signature 549 563 6.4E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 PRINTS PR00344 Bacterial sensor protein C-terminal signature 584 602 6.4E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 PRINTS PR00344 Bacterial sensor protein C-terminal signature 608 621 6.4E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 SUPERFAMILY SSF55785 17 130 1.16E-16 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 SMART SM00387 511 624 4.9E-38 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 Gene3D G3DSA:3.30.450.20 1 126 1.5E-16 T 14-10-2018 TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 Gene3D G3DSA:1.10.287.130 376 463 6.3E-24 T 14-10-2018 TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 SMART SM00086 336 376 0.63 T 14-10-2018 IPR001610 PAC motif TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 SMART SM00086 81 122 2.0 T 14-10-2018 IPR001610 PAC motif TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 SMART SM00086 206 248 2.9E-5 T 14-10-2018 IPR001610 PAC motif TSH58p_15305 d324794a78ebe7bbb0571f767471266a 629 Gene3D G3DSA:3.30.450.20 127 246 1.1E-28 T 14-10-2018 TSH58p_21050 77ff293d98d7f8cc40dce1b607458a50 695 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 565 687 3.9E-17 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_21050 77ff293d98d7f8cc40dce1b607458a50 695 PRINTS PR00344 Bacterial sensor protein C-terminal signature 616 630 8.3E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_21050 77ff293d98d7f8cc40dce1b607458a50 695 PRINTS PR00344 Bacterial sensor protein C-terminal signature 634 644 8.3E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_21050 77ff293d98d7f8cc40dce1b607458a50 695 PRINTS PR00344 Bacterial sensor protein C-terminal signature 673 686 8.3E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_21050 77ff293d98d7f8cc40dce1b607458a50 695 PRINTS PR00344 Bacterial sensor protein C-terminal signature 647 665 8.3E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_21050 77ff293d98d7f8cc40dce1b607458a50 695 SUPERFAMILY SSF158472 355 402 7.45E-8 T 14-10-2018 TSH58p_21050 77ff293d98d7f8cc40dce1b607458a50 695 Pfam PF00672 HAMP domain 355 402 1.9E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_21050 77ff293d98d7f8cc40dce1b607458a50 695 Gene3D G3DSA:1.20.1480.50 319 412 4.3E-10 T 14-10-2018 TSH58p_21050 77ff293d98d7f8cc40dce1b607458a50 695 Gene3D G3DSA:1.10.287.130 413 515 5.7E-19 T 14-10-2018 TSH58p_21050 77ff293d98d7f8cc40dce1b607458a50 695 SMART SM00387 563 689 3.1E-26 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_21050 77ff293d98d7f8cc40dce1b607458a50 695 SUPERFAMILY SSF47384 431 495 3.73E-6 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_21050 77ff293d98d7f8cc40dce1b607458a50 695 SMART SM00304 353 406 8.5E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_21050 77ff293d98d7f8cc40dce1b607458a50 695 SUPERFAMILY SSF55874 521 687 6.29E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_21050 77ff293d98d7f8cc40dce1b607458a50 695 Gene3D G3DSA:3.30.565.10 521 692 1.4E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_25575 b9a9746f67653c7824f7af6e29535bb3 312 Gene3D G3DSA:3.30.950.10 172 298 1.7E-33 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 TSH58p_25575 b9a9746f67653c7824f7af6e29535bb3 312 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 57 268 3.6E-47 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 TSH58p_25575 b9a9746f67653c7824f7af6e29535bb3 312 Gene3D G3DSA:3.40.1010.10 55 171 3.1E-42 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 TSH58p_25575 b9a9746f67653c7824f7af6e29535bb3 312 SUPERFAMILY SSF53790 53 290 7.98E-69 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 TSH58p_25575 b9a9746f67653c7824f7af6e29535bb3 312 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 57 288 4.5E-78 T 14-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TSH58p_01610 75647361910f5afc136dfddbf61ab8bc 1124 Pfam PF02559 CarD-like/TRCF domain 463 556 2.0E-14 T 14-10-2018 IPR003711 CarD-like/TRCF domain TSH58p_01610 75647361910f5afc136dfddbf61ab8bc 1124 SMART SM01058 462 558 3.1E-15 T 14-10-2018 IPR003711 CarD-like/TRCF domain TSH58p_01610 75647361910f5afc136dfddbf61ab8bc 1124 SMART SM00982 980 1079 2.8E-20 T 14-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 TSH58p_01610 75647361910f5afc136dfddbf61ab8bc 1124 Pfam PF00270 DEAD/DEAH box helicase 590 744 2.9E-16 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TSH58p_01610 75647361910f5afc136dfddbf61ab8bc 1124 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 59 1098 23.221 T 14-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 TSH58p_01610 75647361910f5afc136dfddbf61ab8bc 1124 Gene3D G3DSA:2.30.30.840 466 523 3.3E-180 T 14-10-2018 TSH58p_01610 75647361910f5afc136dfddbf61ab8bc 1124 SMART SM00490 808 892 1.6E-16 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_01610 75647361910f5afc136dfddbf61ab8bc 1124 Gene3D G3DSA:3.40.50.300 524 763 3.3E-180 T 14-10-2018 TSH58p_01610 75647361910f5afc136dfddbf61ab8bc 1124 Gene3D G3DSA:3.40.50.11180 66 322 6.6E-52 T 14-10-2018 TSH58p_01610 75647361910f5afc136dfddbf61ab8bc 1124 SUPERFAMILY SSF143517 972 1115 1.16E-24 T 14-10-2018 IPR037235 TRCF-like, C-terminal domain TSH58p_01610 75647361910f5afc136dfddbf61ab8bc 1124 Gene3D G3DSA:3.40.50.300 462 969 3.3E-180 T 14-10-2018 TSH58p_01610 75647361910f5afc136dfddbf61ab8bc 1124 Pfam PF03461 TRCF domain 982 1067 4.5E-20 T 14-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 TSH58p_01610 75647361910f5afc136dfddbf61ab8bc 1124 Gene3D G3DSA:3.90.1150.50 977 1117 6.1E-22 T 14-10-2018 IPR037235 TRCF-like, C-terminal domain TSH58p_01610 75647361910f5afc136dfddbf61ab8bc 1124 Pfam PF00271 Helicase conserved C-terminal domain 787 892 4.0E-15 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_01610 75647361910f5afc136dfddbf61ab8bc 1124 SUPERFAMILY SSF52540 634 905 1.25E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_01610 75647361910f5afc136dfddbf61ab8bc 1124 Gene3D G3DSA:3.30.2060.10 156 242 6.6E-52 T 14-10-2018 TSH58p_01610 75647361910f5afc136dfddbf61ab8bc 1124 SUPERFAMILY SSF52540 45 329 1.4E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_01610 75647361910f5afc136dfddbf61ab8bc 1124 SUPERFAMILY SSF141259 460 523 9.55E-14 T 14-10-2018 IPR036101 CarD-like/TRCF domain superfamily TSH58p_01610 75647361910f5afc136dfddbf61ab8bc 1124 SMART SM00487 582 772 1.5E-29 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSH58p_22300 22b1e0db687752fbe55e5b3471405f2a 800 SUPERFAMILY SSF47240 34 75 1.11E-7 T 14-10-2018 IPR009078 Ferritin-like superfamily TSH58p_22300 22b1e0db687752fbe55e5b3471405f2a 800 Gene3D G3DSA:3.40.1110.10 498 618 7.6E-91 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TSH58p_22300 22b1e0db687752fbe55e5b3471405f2a 800 Gene3D G3DSA:1.10.620.20 30 92 1.3E-7 T 14-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 TSH58p_22300 22b1e0db687752fbe55e5b3471405f2a 800 Pfam PF00122 E1-E2 ATPase 285 465 1.5E-54 T 14-10-2018 TSH58p_22300 22b1e0db687752fbe55e5b3471405f2a 800 Gene3D G3DSA:2.70.150.20 278 390 4.8E-44 T 14-10-2018 TSH58p_22300 22b1e0db687752fbe55e5b3471405f2a 800 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 213 795 7.0E-190 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TSH58p_22300 22b1e0db687752fbe55e5b3471405f2a 800 PRINTS PR00943 Copper-transporting ATPase signature 470 485 3.0E-15 T 14-10-2018 TSH58p_22300 22b1e0db687752fbe55e5b3471405f2a 800 PRINTS PR00943 Copper-transporting ATPase signature 663 680 3.0E-15 T 14-10-2018 TSH58p_22300 22b1e0db687752fbe55e5b3471405f2a 800 PRINTS PR00943 Copper-transporting ATPase signature 254 273 3.0E-15 T 14-10-2018 TSH58p_22300 22b1e0db687752fbe55e5b3471405f2a 800 PRINTS PR00943 Copper-transporting ATPase signature 274 292 3.0E-15 T 14-10-2018 TSH58p_22300 22b1e0db687752fbe55e5b3471405f2a 800 PRINTS PR00943 Copper-transporting ATPase signature 196 215 3.0E-15 T 14-10-2018 TSH58p_22300 22b1e0db687752fbe55e5b3471405f2a 800 PRINTS PR00943 Copper-transporting ATPase signature 408 422 3.0E-15 T 14-10-2018 TSH58p_22300 22b1e0db687752fbe55e5b3471405f2a 800 Gene3D G3DSA:3.40.50.1000 468 738 7.6E-91 T 14-10-2018 IPR023214 HAD superfamily TSH58p_22300 22b1e0db687752fbe55e5b3471405f2a 800 SUPERFAMILY SSF81665 250 772 3.27E-13 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 TSH58p_22300 22b1e0db687752fbe55e5b3471405f2a 800 Pfam PF04945 YHS domain 32 77 3.8E-16 T 14-10-2018 IPR007029 YHS domain TSH58p_22300 22b1e0db687752fbe55e5b3471405f2a 800 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 256 765 3.1E-87 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TSH58p_22300 22b1e0db687752fbe55e5b3471405f2a 800 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 686 705 4.4E-28 T 14-10-2018 TSH58p_22300 22b1e0db687752fbe55e5b3471405f2a 800 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 611 622 4.4E-28 T 14-10-2018 TSH58p_22300 22b1e0db687752fbe55e5b3471405f2a 800 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 335 349 4.4E-28 T 14-10-2018 TSH58p_22300 22b1e0db687752fbe55e5b3471405f2a 800 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 709 721 4.4E-28 T 14-10-2018 TSH58p_22300 22b1e0db687752fbe55e5b3471405f2a 800 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 487 501 4.4E-28 T 14-10-2018 TSH58p_22300 22b1e0db687752fbe55e5b3471405f2a 800 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 633 643 4.4E-28 T 14-10-2018 TSH58p_22300 22b1e0db687752fbe55e5b3471405f2a 800 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 489 495 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 TSH58p_22300 22b1e0db687752fbe55e5b3471405f2a 800 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 192 796 3.7E-178 T 14-10-2018 TSH58p_22300 22b1e0db687752fbe55e5b3471405f2a 800 SUPERFAMILY SSF56784 485 793 9.62E-58 T 14-10-2018 IPR036412 HAD-like superfamily TSH58p_22300 22b1e0db687752fbe55e5b3471405f2a 800 SMART SM00746 34 72 9.1E-10 T 14-10-2018 IPR011017 TRASH domain TSH58p_22300 22b1e0db687752fbe55e5b3471405f2a 800 SUPERFAMILY SSF81653 287 385 5.49E-26 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 TSH58p_22300 22b1e0db687752fbe55e5b3471405f2a 800 Pfam PF00702 haloacid dehalogenase-like hydrolase 483 700 2.8E-46 T 14-10-2018 TSH58p_16680 ebf785a39e4e5f3b1de99d2c9442cca3 144 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 9 129 2.2E-23 T 14-10-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 TSH58p_16680 ebf785a39e4e5f3b1de99d2c9442cca3 144 SUPERFAMILY SSF47188 5 131 5.49E-23 T 14-10-2018 IPR035938 Hemerythrin-like superfamily TSH58p_16680 ebf785a39e4e5f3b1de99d2c9442cca3 144 Pfam PF01814 Hemerythrin HHE cation binding domain 18 130 1.9E-7 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 TSH58p_16680 ebf785a39e4e5f3b1de99d2c9442cca3 144 Gene3D G3DSA:1.20.120.50 3 137 3.6E-24 T 14-10-2018 IPR035938 Hemerythrin-like superfamily TSH58p_20165 a50b1cd8615caf2cbd7e71a7f6e50fe8 206 TIGRFAM TIGR02161 napC_nirT: periplasmic nitrate (or nitrite) reductase c-type cytochrome, NapC/NirT family 9 193 4.9E-97 T 14-10-2018 IPR011885 Periplasmic nitrate reductase c-type cytochrome, NapC/NirT GO:0016021|GO:0019333|GO:0020037 TSH58p_20165 a50b1cd8615caf2cbd7e71a7f6e50fe8 206 Pfam PF03264 NapC/NirT cytochrome c family, N-terminal region 18 192 1.7E-76 T 14-10-2018 IPR005126 NapC/NirT cytochrome c, N-terminal TSH58p_20165 a50b1cd8615caf2cbd7e71a7f6e50fe8 206 SUPERFAMILY SSF48695 16 195 2.61E-65 T 14-10-2018 IPR036280 Multiheme cytochrome superfamily TSH58p_20165 a50b1cd8615caf2cbd7e71a7f6e50fe8 206 Gene3D G3DSA:1.10.3820.10 19 195 4.8E-37 T 14-10-2018 IPR038266 NapC/NirT cytochrome c superfamily TSH58p_20165 a50b1cd8615caf2cbd7e71a7f6e50fe8 206 PIRSF PIRSF000013 2 202 1.2E-109 T 14-10-2018 IPR024717 Denitrification system component NapC/NirT/NrfH GO:0016021|GO:0019333|GO:0020037 TSH58p_05945 054d7b2af6130138016d7ff081906ff8 211 SUPERFAMILY SSF52096 18 200 2.7E-74 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_05945 054d7b2af6130138016d7ff081906ff8 211 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 98 109 - T 14-10-2018 IPR018215 ClpP, Ser active site TSH58p_05945 054d7b2af6130138016d7ff081906ff8 211 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 120 133 - T 14-10-2018 IPR033135 ClpP, histidine active site TSH58p_05945 054d7b2af6130138016d7ff081906ff8 211 PRINTS PR00127 Clp protease catalytic subunit P signature 67 87 1.3E-51 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TSH58p_05945 054d7b2af6130138016d7ff081906ff8 211 PRINTS PR00127 Clp protease catalytic subunit P signature 176 195 1.3E-51 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TSH58p_05945 054d7b2af6130138016d7ff081906ff8 211 PRINTS PR00127 Clp protease catalytic subunit P signature 119 138 1.3E-51 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TSH58p_05945 054d7b2af6130138016d7ff081906ff8 211 PRINTS PR00127 Clp protease catalytic subunit P signature 27 42 1.3E-51 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TSH58p_05945 054d7b2af6130138016d7ff081906ff8 211 PRINTS PR00127 Clp protease catalytic subunit P signature 98 115 1.3E-51 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TSH58p_05945 054d7b2af6130138016d7ff081906ff8 211 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 11 201 43.105 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TSH58p_05945 054d7b2af6130138016d7ff081906ff8 211 Pfam PF00574 Clp protease 21 200 4.0E-88 T 14-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA TSH58p_05945 054d7b2af6130138016d7ff081906ff8 211 Gene3D G3DSA:3.90.226.10 2 203 1.2E-86 T 14-10-2018 TSH58p_05945 054d7b2af6130138016d7ff081906ff8 211 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 10 200 2.5E-98 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TSH58p_01835 4988ce45bd53f024c6b8937c7e6bbf8d 398 Pfam PF13538 UvrD-like helicase C-terminal domain 334 380 7.5E-16 T 14-10-2018 IPR027785 UvrD-like helicase C-terminal domain TSH58p_01835 4988ce45bd53f024c6b8937c7e6bbf8d 398 Gene3D G3DSA:3.40.50.300 6 168 3.6E-29 T 14-10-2018 TSH58p_01835 4988ce45bd53f024c6b8937c7e6bbf8d 398 SUPERFAMILY SSF52540 2 386 7.19E-33 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_01835 4988ce45bd53f024c6b8937c7e6bbf8d 398 Pfam PF13604 AAA domain 31 194 3.6E-18 T 14-10-2018 TSH58p_01835 4988ce45bd53f024c6b8937c7e6bbf8d 398 Gene3D G3DSA:3.40.50.300 311 388 7.5E-14 T 14-10-2018 TSH58p_15125 6debe731651a9e7d81280cf795c06ff6 1397 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 9 1392 0.0 T 14-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_15125 6debe731651a9e7d81280cf795c06ff6 1397 Pfam PF04560 RNA polymerase Rpb2, domain 7 1319 1393 6.8E-27 T 14-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_15125 6debe731651a9e7d81280cf795c06ff6 1397 Pfam PF04563 RNA polymerase beta subunit 27 530 6.9E-34 T 14-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_15125 6debe731651a9e7d81280cf795c06ff6 1397 Gene3D G3DSA:2.40.270.10 1052 1295 5.7E-81 T 14-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_15125 6debe731651a9e7d81280cf795c06ff6 1397 Pfam PF00562 RNA polymerase Rpb2, domain 6 750 1317 3.9E-169 T 14-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_15125 6debe731651a9e7d81280cf795c06ff6 1397 Gene3D G3DSA:3.90.1110.10 164 268 3.0E-23 T 14-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_15125 6debe731651a9e7d81280cf795c06ff6 1397 Gene3D G3DSA:3.90.1100.10 475 659 2.1E-73 T 14-10-2018 TSH58p_15125 6debe731651a9e7d81280cf795c06ff6 1397 Gene3D G3DSA:2.40.270.10 825 864 4.2E-7 T 14-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_15125 6debe731651a9e7d81280cf795c06ff6 1397 Gene3D G3DSA:3.90.1800.10 1305 1358 8.9E-11 T 14-10-2018 TSH58p_15125 6debe731651a9e7d81280cf795c06ff6 1397 Gene3D G3DSA:2.40.50.100 747 824 1.5E-30 T 14-10-2018 TSH58p_15125 6debe731651a9e7d81280cf795c06ff6 1397 SUPERFAMILY SSF64484 12 1394 0.0 T 14-10-2018 TSH58p_15125 6debe731651a9e7d81280cf795c06ff6 1397 Gene3D G3DSA:3.90.1110.10 355 474 1.1E-32 T 14-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_15125 6debe731651a9e7d81280cf795c06ff6 1397 Gene3D G3DSA:2.40.50.150 865 986 9.0E-46 T 14-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_15125 6debe731651a9e7d81280cf795c06ff6 1397 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1108 1120 - T 14-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_15125 6debe731651a9e7d81280cf795c06ff6 1397 Pfam PF04565 RNA polymerase Rpb2, domain 3 546 614 2.9E-32 T 14-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_15125 6debe731651a9e7d81280cf795c06ff6 1397 Pfam PF04561 RNA polymerase Rpb2, domain 2 383 487 6.4E-20 T 14-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_15125 6debe731651a9e7d81280cf795c06ff6 1397 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1395 12.462 T 14-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_15125 6debe731651a9e7d81280cf795c06ff6 1397 Pfam PF10385 RNA polymerase beta subunit external 1 domain 624 689 3.6E-24 T 14-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_15125 6debe731651a9e7d81280cf795c06ff6 1397 Gene3D G3DSA:3.90.1100.10 682 746 1.8E-20 T 14-10-2018 TSH58p_15125 6debe731651a9e7d81280cf795c06ff6 1397 Gene3D G3DSA:3.90.1100.10 18 163 4.4E-57 T 14-10-2018 TSH58p_29615 698046b2d3636db1f393a4b6ed6b4f33 274 Gene3D G3DSA:3.40.50.12370 5 273 1.8E-29 T 14-10-2018 TSH58p_29615 698046b2d3636db1f393a4b6ed6b4f33 274 SUPERFAMILY SSF52402 150 272 1.84E-14 T 14-10-2018 TSH58p_29615 698046b2d3636db1f393a4b6ed6b4f33 274 SUPERFAMILY SSF52402 1 140 1.76E-13 T 14-10-2018 TSH58p_29615 698046b2d3636db1f393a4b6ed6b4f33 274 Pfam PF00582 Universal stress protein family 150 272 5.9E-7 T 14-10-2018 IPR006016 UspA TSH58p_29615 698046b2d3636db1f393a4b6ed6b4f33 274 Pfam PF00582 Universal stress protein family 3 140 8.5E-8 T 14-10-2018 IPR006016 UspA TSH58p_29615 698046b2d3636db1f393a4b6ed6b4f33 274 PRINTS PR01438 Universal stress protein signature 3 21 1.9E-5 T 14-10-2018 IPR006015 Universal stress protein A TSH58p_29615 698046b2d3636db1f393a4b6ed6b4f33 274 PRINTS PR01438 Universal stress protein signature 234 246 1.9E-5 T 14-10-2018 IPR006015 Universal stress protein A TSH58p_29615 698046b2d3636db1f393a4b6ed6b4f33 274 PRINTS PR01438 Universal stress protein signature 252 274 1.9E-5 T 14-10-2018 IPR006015 Universal stress protein A TSH58p_32485 0a7c5fadb4cad7946ac30a60cded09ec 67 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 56 1.3E-18 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_32485 0a7c5fadb4cad7946ac30a60cded09ec 67 Gene3D G3DSA:1.20.5.1150 14 52 3.5E-7 T 14-10-2018 IPR038380 Ribosomal protein S21 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_32485 0a7c5fadb4cad7946ac30a60cded09ec 67 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 13 51 4.0E-10 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_32485 0a7c5fadb4cad7946ac30a60cded09ec 67 Pfam PF01165 Ribosomal protein S21 3 55 1.6E-17 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_32485 0a7c5fadb4cad7946ac30a60cded09ec 67 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 55 11.643 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 SUPERFAMILY SSF51120 233 400 2.88E-26 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 SUPERFAMILY SSF141072 2155 2274 4.84E-23 T 14-10-2018 IPR038081 CalX-like domain superfamily TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 614 632 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 285 303 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 95 113 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 980 998 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF03160 Calx-beta domain 2169 2250 7.8E-6 T 14-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF03160 Calx-beta domain 2020 2127 5.4E-5 T 14-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF03160 Calx-beta domain 1910 2004 0.002 T 14-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF03160 Calx-beta domain 1502 1597 8.8E-7 T 14-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 971 989 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1173 1191 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 452 470 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1164 1182 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Gene3D G3DSA:2.150.10.10 2495 2554 1.3E-10 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 461 479 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 SUPERFAMILY SSF51120 1112 1229 1.05E-19 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00094 von Willebrand factor type D domain 1637 1793 8.9E-14 T 14-10-2018 IPR001846 von Willebrand factor, type D domain TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 SUPERFAMILY SSF141072 1502 1623 1.7E-24 T 14-10-2018 IPR038081 CalX-like domain superfamily TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 SUPERFAMILY SSF141072 1909 2030 1.06E-18 T 14-10-2018 IPR038081 CalX-like domain superfamily TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 SMART SM00539 1349 1495 0.0032 T 14-10-2018 IPR003886 NIDO domain GO:0007160 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 989 1007 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Gene3D G3DSA:2.150.10.10 2604 2719 4.1E-24 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Gene3D G3DSA:2.150.10.10 1110 1161 5.0E-11 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 SUPERFAMILY SSF51120 52 208 2.75E-28 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Gene3D G3DSA:2.150.10.10 2555 2603 8.9E-13 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Gene3D G3DSA:2.150.10.10 1162 1264 1.6E-14 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 276 294 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 596 614 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 SUPERFAMILY SSF51120 908 1044 3.66E-24 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 PRINTS PR00313 NodO calcium binding signature 90 98 1.1E-9 T 14-10-2018 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 PRINTS PR00313 NodO calcium binding signature 69 80 1.1E-9 T 14-10-2018 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 PRINTS PR00313 NodO calcium binding signature 271 279 1.1E-9 T 14-10-2018 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 PRINTS PR00313 NodO calcium binding signature 307 316 1.1E-9 T 14-10-2018 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 104 122 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 2634 2652 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 SMART SM00216 1622 1792 4.5E-6 T 14-10-2018 IPR001846 von Willebrand factor, type D domain TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Gene3D G3DSA:2.150.10.10 451 566 1.8E-23 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Gene3D G3DSA:2.150.10.10 615 731 1.8E-21 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 797 815 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 2589 2607 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 587 605 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 SUPERFAMILY SSF51120 576 729 3.27E-25 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Gene3D G3DSA:2.60.40.2030 2159 2271 9.1E-18 T 14-10-2018 IPR038081 CalX-like domain superfamily TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Gene3D G3DSA:2.60.40.2030 1910 2029 7.4E-13 T 14-10-2018 IPR038081 CalX-like domain superfamily TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Gene3D G3DSA:2.60.40.2030 2034 2146 3.0E-15 T 14-10-2018 IPR038081 CalX-like domain superfamily TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Gene3D G3DSA:2.60.40.2030 1503 1622 5.5E-19 T 14-10-2018 IPR038081 CalX-like domain superfamily TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 788 806 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 806 824 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 2598 2616 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Gene3D G3DSA:2.150.10.10 931 1097 4.5E-27 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Gene3D G3DSA:2.150.10.10 803 930 1.5E-25 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Gene3D G3DSA:2.150.10.10 571 614 2.1E-10 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Gene3D G3DSA:2.150.10.10 273 402 7.4E-25 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 SUPERFAMILY SSF51120 741 806 2.62E-14 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 SUPERFAMILY SSF51120 414 561 4.45E-23 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Gene3D G3DSA:2.150.10.10 226 272 6.7E-11 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 2580 2598 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 SUPERFAMILY SSF51120 2568 2707 2.22E-26 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 443 461 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 288 304 0.76 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 993 1009 0.015 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 234 251 0.71 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 98 115 0.13 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 792 808 0.096 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2495 2510 1.3 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 590 607 0.015 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 446 463 0.056 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 428 445 0.039 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 270 287 0.032 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 975 991 0.085 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2530 2546 0.029 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 464 481 0.0062 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2619 2636 0.0021 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2583 2600 0.14 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 957 973 0.09 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 608 625 0.071 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1168 1184 0.022 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 627 643 0.0087 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2565 2582 0.016 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 755 772 5.2 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 827 844 0.013 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 774 790 0.64 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2640 2654 3.4 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 116 133 0.19 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1150 1166 0.084 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 253 269 0.75 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2511 2528 61.0 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 63 79 0.073 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2602 2618 2.2 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 81 97 3.8 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1132 1148 0.15 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 809 826 0.61 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2548 2564 1.1 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 SMART SM00237 2020 2127 0.0036 T 14-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 SMART SM00237 1889 2004 0.036 T 14-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 SMART SM00237 2145 2250 0.0016 T 14-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 SMART SM00237 1497 1598 1.4E-5 T 14-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Pfam PF06119 Nidogen-like 1403 1490 2.0E-8 T 14-10-2018 IPR003886 NIDO domain GO:0007160 TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 SUPERFAMILY SSF51120 2454 2554 6.54E-17 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Gene3D G3DSA:2.150.10.10 732 802 4.8E-14 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 605 623 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Gene3D G3DSA:2.150.10.10 94 218 1.3E-29 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Gene3D G3DSA:2.150.10.10 413 450 1.6E-7 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 Gene3D G3DSA:2.150.10.10 40 93 2.0E-9 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 113 131 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 SUPERFAMILY SSF51120 795 930 4.84E-20 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20185 ea13f4891c4df8d0521c724d3952d72f 2722 SUPERFAMILY SSF141072 2035 2147 6.67E-20 T 14-10-2018 IPR038081 CalX-like domain superfamily TSH58p_06700 172a07aa838b1a27341e172ee23b46d7 1171 SUPERFAMILY SSF52518 17 240 9.42E-20 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_06700 172a07aa838b1a27341e172ee23b46d7 1171 Gene3D G3DSA:3.40.50.970 9 220 6.6E-25 T 14-10-2018 TSH58p_06700 172a07aa838b1a27341e172ee23b46d7 1171 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 451 600 4.3E-6 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TSH58p_06700 172a07aa838b1a27341e172ee23b46d7 1171 SUPERFAMILY SSF52518 431 618 6.15E-15 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_06700 172a07aa838b1a27341e172ee23b46d7 1171 SUPERFAMILY SSF53323 717 972 7.32E-31 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TSH58p_06700 172a07aa838b1a27341e172ee23b46d7 1171 Gene3D G3DSA:3.40.920.10 715 918 2.6E-17 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TSH58p_06700 172a07aa838b1a27341e172ee23b46d7 1171 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 725 912 4.8E-24 T 14-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TSH58p_06700 172a07aa838b1a27341e172ee23b46d7 1171 SUPERFAMILY SSF52922 266 395 4.19E-10 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSH58p_11400 448cb90be253b5fdf96f70c288820804 909 Pfam PF00009 Elongation factor Tu GTP binding domain 411 567 1.9E-33 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_11400 448cb90be253b5fdf96f70c288820804 909 Gene3D G3DSA:2.40.30.10 811 908 6.0E-33 T 14-10-2018 TSH58p_11400 448cb90be253b5fdf96f70c288820804 909 Pfam PF11987 Translation-initiation factor 2 693 799 2.7E-39 T 14-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 TSH58p_11400 448cb90be253b5fdf96f70c288820804 909 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 9 907 17.41 T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 TSH58p_11400 448cb90be253b5fdf96f70c288820804 909 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 331 380 6.1E-16 T 14-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal TSH58p_11400 448cb90be253b5fdf96f70c288820804 909 SUPERFAMILY SSF50447 580 663 4.12E-25 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSH58p_11400 448cb90be253b5fdf96f70c288820804 909 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 20 57 2.3E-8 T 14-10-2018 IPR013575 Initiation factor 2 associated domain, bacterial TSH58p_11400 448cb90be253b5fdf96f70c288820804 909 Gene3D G3DSA:3.40.50.300 403 578 1.3E-71 T 14-10-2018 TSH58p_11400 448cb90be253b5fdf96f70c288820804 909 SUPERFAMILY SSF50447 811 907 2.95E-32 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSH58p_11400 448cb90be253b5fdf96f70c288820804 909 SUPERFAMILY SSF52540 404 579 1.42E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_11400 448cb90be253b5fdf96f70c288820804 909 SUPERFAMILY SSF52156 690 816 1.29E-37 T 14-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily TSH58p_11400 448cb90be253b5fdf96f70c288820804 909 Gene3D G3DSA:3.40.50.10050 702 810 5.5E-39 T 14-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily TSH58p_11400 448cb90be253b5fdf96f70c288820804 909 Gene3D G3DSA:2.40.30.10 579 695 6.6E-41 T 14-10-2018 TSH58p_11400 448cb90be253b5fdf96f70c288820804 909 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 323 907 2.5E-252 T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 TSH58p_11400 448cb90be253b5fdf96f70c288820804 909 ProSitePatterns PS01176 Initiation factor 2 signature. 860 882 - T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 TSH58p_11400 448cb90be253b5fdf96f70c288820804 909 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 409 563 5.3E-34 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSH58p_10695 cfb89830d1bdfbb81f637d11b1f36d34 880 Gene3D G3DSA:1.10.1420.10 386 511 1.5E-82 T 14-10-2018 TSH58p_10695 cfb89830d1bdfbb81f637d11b1f36d34 880 Pfam PF00488 MutS domain V 622 809 1.0E-82 T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 TSH58p_10695 cfb89830d1bdfbb81f637d11b1f36d34 880 SUPERFAMILY SSF52540 575 809 4.97E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_10695 cfb89830d1bdfbb81f637d11b1f36d34 880 Pfam PF05190 MutS family domain IV 432 526 1.1E-15 T 14-10-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 TSH58p_10695 cfb89830d1bdfbb81f637d11b1f36d34 880 SUPERFAMILY SSF48334 266 572 8.5E-75 T 14-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily TSH58p_10695 cfb89830d1bdfbb81f637d11b1f36d34 880 Gene3D G3DSA:3.40.50.300 578 825 6.2E-92 T 14-10-2018 TSH58p_10695 cfb89830d1bdfbb81f637d11b1f36d34 880 Gene3D G3DSA:1.10.1420.10 265 567 1.5E-82 T 14-10-2018 TSH58p_10695 cfb89830d1bdfbb81f637d11b1f36d34 880 Pfam PF01624 MutS domain I 1 115 2.8E-42 T 14-10-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 TSH58p_10695 cfb89830d1bdfbb81f637d11b1f36d34 880 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 1 876 6.8E-259 T 14-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 TSH58p_10695 cfb89830d1bdfbb81f637d11b1f36d34 880 PIRSF PIRSF037677 241 824 3.3E-112 T 14-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 TSH58p_10695 cfb89830d1bdfbb81f637d11b1f36d34 880 PIRSF PIRSF037677 1 200 1.8E-32 T 14-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 TSH58p_10695 cfb89830d1bdfbb81f637d11b1f36d34 880 SUPERFAMILY SSF53150 113 279 1.03E-35 T 14-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 TSH58p_10695 cfb89830d1bdfbb81f637d11b1f36d34 880 Gene3D G3DSA:3.40.1170.10 1 117 1.5E-47 T 14-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 TSH58p_10695 cfb89830d1bdfbb81f637d11b1f36d34 880 SUPERFAMILY SSF55271 1 111 8.37E-40 T 14-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 TSH58p_10695 cfb89830d1bdfbb81f637d11b1f36d34 880 Gene3D G3DSA:3.30.420.110 123 256 6.6E-24 T 14-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 TSH58p_10695 cfb89830d1bdfbb81f637d11b1f36d34 880 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 700 716 - T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 TSH58p_10695 cfb89830d1bdfbb81f637d11b1f36d34 880 Pfam PF05188 MutS domain II 124 249 2.2E-20 T 14-10-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 TSH58p_10695 cfb89830d1bdfbb81f637d11b1f36d34 880 SMART SM00534 619 806 2.9E-110 T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 TSH58p_10695 cfb89830d1bdfbb81f637d11b1f36d34 880 Pfam PF05192 MutS domain III 268 567 6.6E-40 T 14-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 TSH58p_10695 cfb89830d1bdfbb81f637d11b1f36d34 880 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 1 871 23.12 T 14-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 TSH58p_10695 cfb89830d1bdfbb81f637d11b1f36d34 880 SMART SM00533 282 599 8.6E-73 T 14-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 TSH58p_22855 9cc236359f6b2ea3a97515b973484aa2 253 Gene3D G3DSA:3.30.1330.30 7 96 1.5E-7 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like TSH58p_22855 9cc236359f6b2ea3a97515b973484aa2 253 SUPERFAMILY SSF75217 120 250 1.31E-24 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases TSH58p_22855 9cc236359f6b2ea3a97515b973484aa2 253 SUPERFAMILY SSF55315 7 85 4.24E-7 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like TSH58p_22855 9cc236359f6b2ea3a97515b973484aa2 253 Pfam PF00588 SpoU rRNA Methylase family 121 246 5.5E-22 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TSH58p_22855 9cc236359f6b2ea3a97515b973484aa2 253 Gene3D G3DSA:3.40.1280.10 112 253 1.8E-29 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TSH58p_27430 4f3a6b3494b2f601d92ef945b2e4d077 756 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 622 650 0.028 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TSH58p_27430 4f3a6b3494b2f601d92ef945b2e4d077 756 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 569 607 0.91 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TSH58p_27430 4f3a6b3494b2f601d92ef945b2e4d077 756 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 667 703 2.5E-4 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TSH58p_27430 4f3a6b3494b2f601d92ef945b2e4d077 756 SMART SM00434 17 484 2.3E-217 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TSH58p_27430 4f3a6b3494b2f601d92ef945b2e4d077 756 SUPERFAMILY SSF101904 520 754 1.96E-47 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal TSH58p_27430 4f3a6b3494b2f601d92ef945b2e4d077 756 Gene3D G3DSA:3.90.199.10 38 505 2.4E-179 T 14-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 TSH58p_27430 4f3a6b3494b2f601d92ef945b2e4d077 756 Gene3D G3DSA:1.10.268.10 392 477 2.4E-179 T 14-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 TSH58p_27430 4f3a6b3494b2f601d92ef945b2e4d077 756 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 16 755 1.1E-257 T 14-10-2018 TSH58p_27430 4f3a6b3494b2f601d92ef945b2e4d077 756 Gene3D G3DSA:2.120.10.90 523 716 6.5E-15 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal TSH58p_27430 4f3a6b3494b2f601d92ef945b2e4d077 756 Gene3D G3DSA:3.30.1360.40 258 354 2.4E-179 T 14-10-2018 TSH58p_27430 4f3a6b3494b2f601d92ef945b2e4d077 756 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 10 756 32.093 T 14-10-2018 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TSH58p_27430 4f3a6b3494b2f601d92ef945b2e4d077 756 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 38 479 7.2E-136 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TSH58p_27430 4f3a6b3494b2f601d92ef945b2e4d077 756 SUPERFAMILY SSF56719 37 505 6.8E-151 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 TSH58p_30225 00169f842b098addfd863f4410b9e50e 332 Pfam PF03466 LysR substrate binding domain 89 292 1.8E-45 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_30225 00169f842b098addfd863f4410b9e50e 332 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 4.3E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_30225 00169f842b098addfd863f4410b9e50e 332 Gene3D G3DSA:3.40.190.10 163 264 1.2E-68 T 14-10-2018 TSH58p_30225 00169f842b098addfd863f4410b9e50e 332 Gene3D G3DSA:1.10.10.10 3 89 6.5E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_30225 00169f842b098addfd863f4410b9e50e 332 SUPERFAMILY SSF46785 4 86 1.75E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_30225 00169f842b098addfd863f4410b9e50e 332 Gene3D G3DSA:3.40.190.10 91 291 1.2E-68 T 14-10-2018 TSH58p_30225 00169f842b098addfd863f4410b9e50e 332 SUPERFAMILY SSF53850 90 296 3.26E-48 T 14-10-2018 TSH58p_09725 7db5cde5e563b2b659752319cc5c22f9 357 SUPERFAMILY SSF50331 236 355 6.8E-30 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSH58p_09725 7db5cde5e563b2b659752319cc5c22f9 357 SMART SM00382 28 211 6.0E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_09725 7db5cde5e563b2b659752319cc5c22f9 357 Pfam PF00005 ABC transporter 20 161 1.1E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_09725 7db5cde5e563b2b659752319cc5c22f9 357 Gene3D G3DSA:2.40.50.140 284 339 5.2E-32 T 14-10-2018 TSH58p_09725 7db5cde5e563b2b659752319cc5c22f9 357 Gene3D G3DSA:2.40.50.940 222 348 5.2E-32 T 14-10-2018 TSH58p_09725 7db5cde5e563b2b659752319cc5c22f9 357 Gene3D G3DSA:3.40.50.300 4 221 2.1E-62 T 14-10-2018 TSH58p_09725 7db5cde5e563b2b659752319cc5c22f9 357 SUPERFAMILY SSF52540 4 243 4.78E-87 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_09725 7db5cde5e563b2b659752319cc5c22f9 357 Pfam PF08402 TOBE domain 277 347 6.5E-12 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TSH58p_09725 7db5cde5e563b2b659752319cc5c22f9 357 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_32165 9e50d518ae3b1dc6e5291d675393963a 239 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 236 2.2E-38 T 14-10-2018 TSH58p_32165 9e50d518ae3b1dc6e5291d675393963a 239 Gene3D G3DSA:3.40.50.720 8 238 6.6E-56 T 14-10-2018 TSH58p_32165 9e50d518ae3b1dc6e5291d675393963a 239 SUPERFAMILY SSF51735 14 238 2.06E-54 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_32165 9e50d518ae3b1dc6e5291d675393963a 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 8.5E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_32165 9e50d518ae3b1dc6e5291d675393963a 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 8.5E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_32165 9e50d518ae3b1dc6e5291d675393963a 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 8.5E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_32165 9e50d518ae3b1dc6e5291d675393963a 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 1.2E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_32165 9e50d518ae3b1dc6e5291d675393963a 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 1.2E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_32165 9e50d518ae3b1dc6e5291d675393963a 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 1.2E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_32165 9e50d518ae3b1dc6e5291d675393963a 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 200 220 1.2E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_32165 9e50d518ae3b1dc6e5291d675393963a 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 1.2E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_12015 6ded748a7ecdb1d0e078935cd58e77c5 389 Pfam PF04055 Radical SAM superfamily 124 294 2.9E-18 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSH58p_12015 6ded748a7ecdb1d0e078935cd58e77c5 389 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 20 367 73.226 T 14-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 TSH58p_12015 6ded748a7ecdb1d0e078935cd58e77c5 389 PIRSF PIRSF006004 15 381 4.0E-144 T 14-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 TSH58p_12015 6ded748a7ecdb1d0e078935cd58e77c5 389 SUPERFAMILY SSF102114 117 325 1.01E-14 T 14-10-2018 TSH58p_12015 6ded748a7ecdb1d0e078935cd58e77c5 389 Gene3D G3DSA:1.10.150.530 20 80 8.2E-20 T 14-10-2018 TSH58p_12015 6ded748a7ecdb1d0e078935cd58e77c5 389 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 18 365 1.7E-125 T 14-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 TSH58p_12015 6ded748a7ecdb1d0e078935cd58e77c5 389 Gene3D G3DSA:3.20.20.70 82 352 3.6E-108 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_26105 06cdd8bc6328189384bf1b35badf8b6c 317 Gene3D G3DSA:1.10.3470.10 1 317 8.1E-51 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_26105 06cdd8bc6328189384bf1b35badf8b6c 317 SUPERFAMILY SSF81345 3 313 3.27E-51 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_26105 06cdd8bc6328189384bf1b35badf8b6c 317 Pfam PF01032 FecCD transport family 23 313 1.3E-49 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TSH58p_30895 ce3e520769d16e480cfb65889426a692 326 SUPERFAMILY SSF53850 31 257 1.28E-43 T 14-10-2018 TSH58p_30895 ce3e520769d16e480cfb65889426a692 326 Gene3D G3DSA:3.40.190.10 116 215 7.1E-73 T 14-10-2018 TSH58p_30895 ce3e520769d16e480cfb65889426a692 326 Gene3D G3DSA:3.40.190.10 32 311 7.1E-73 T 14-10-2018 TSH58p_30895 ce3e520769d16e480cfb65889426a692 326 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 33 319 7.5E-60 T 14-10-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 TSH58p_30895 ce3e520769d16e480cfb65889426a692 326 Pfam PF09084 NMT1/THI5 like 43 256 8.0E-22 T 14-10-2018 IPR015168 SsuA/THI5-like TSH58p_30895 ce3e520769d16e480cfb65889426a692 326 SMART SM00062 31 259 0.007 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_30895 ce3e520769d16e480cfb65889426a692 326 Gene3D G3DSA:1.10.8.450 247 280 7.1E-73 T 14-10-2018 TSH58p_10870 e90e173f24bebcfab2484019b569fb88 389 Gene3D G3DSA:3.40.50.2000 199 356 1.7E-20 T 14-10-2018 TSH58p_10870 e90e173f24bebcfab2484019b569fb88 389 SUPERFAMILY SSF53756 1 354 2.51E-20 T 14-10-2018 TSH58p_10870 e90e173f24bebcfab2484019b569fb88 389 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 276 350 6.1E-10 T 14-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 TSH58p_18065 21ea2eaba12056a50b425d7b23806b35 419 TIGRFAM TIGR03588 PseC: UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase 16 413 6.3E-143 T 14-10-2018 IPR020026 UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase TSH58p_18065 21ea2eaba12056a50b425d7b23806b35 419 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 24 409 3.3E-112 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase TSH58p_18065 21ea2eaba12056a50b425d7b23806b35 419 Gene3D G3DSA:3.90.1150.10 288 414 7.5E-33 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_18065 21ea2eaba12056a50b425d7b23806b35 419 PIRSF PIRSF000390 12 417 8.8E-110 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase TSH58p_18065 21ea2eaba12056a50b425d7b23806b35 419 Gene3D G3DSA:3.40.640.10 12 287 3.9E-88 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_18065 21ea2eaba12056a50b425d7b23806b35 419 SUPERFAMILY SSF53383 16 413 6.4E-103 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_18265 a4d4b8eecd92d11fdecac5e450d54acf 496 Pfam PF13489 Methyltransferase domain 51 208 1.1E-19 T 14-10-2018 TSH58p_18265 a4d4b8eecd92d11fdecac5e450d54acf 496 Gene3D G3DSA:3.40.50.150 27 222 4.8E-31 T 14-10-2018 TSH58p_18265 a4d4b8eecd92d11fdecac5e450d54acf 496 SUPERFAMILY SSF53448 261 493 4.88E-49 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_18265 a4d4b8eecd92d11fdecac5e450d54acf 496 Gene3D G3DSA:3.90.550.10 242 487 3.9E-37 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_18265 a4d4b8eecd92d11fdecac5e450d54acf 496 SUPERFAMILY SSF53335 32 214 2.28E-29 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_18265 a4d4b8eecd92d11fdecac5e450d54acf 496 Pfam PF00535 Glycosyl transferase family 2 262 389 4.0E-22 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_18755 eb6eb32a053013319c1478ee51495373 251 SUPERFAMILY SSF55681 33 241 5.8E-67 T 14-10-2018 TSH58p_18755 eb6eb32a053013319c1478ee51495373 251 Hamap MF_00013 Octanoyltransferase [lipB]. 30 242 36.055 T 14-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TSH58p_18755 eb6eb32a053013319c1478ee51495373 251 Gene3D G3DSA:3.30.930.10 29 239 1.1E-65 T 14-10-2018 TSH58p_18755 eb6eb32a053013319c1478ee51495373 251 Pfam PF03099 Biotin/lipoate A/B protein ligase family 83 195 2.5E-10 T 14-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 TSH58p_18755 eb6eb32a053013319c1478ee51495373 251 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 102 154 1.0E-13 T 14-10-2018 TSH58p_18755 eb6eb32a053013319c1478ee51495373 251 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 97 112 - T 14-10-2018 IPR020605 Octanoyltransferase, conserved site GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 TSH58p_18755 eb6eb32a053013319c1478ee51495373 251 PIRSF PIRSF016262 27 243 2.7E-58 T 14-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TSH58p_18755 eb6eb32a053013319c1478ee51495373 251 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 63 240 7.9E-50 T 14-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TSH58p_01165 3a2cc15b96951714366192c9221af3b6 274 TIGRFAM TIGR03122 one_C_dehyd_C: formylmethanofuran dehydrogenase subunit C 6 270 2.9E-63 T 14-10-2018 IPR017550 Formylmethanofuran dehydrogenase subunit C GO:0015948|GO:0018493|GO:0046914|GO:0055114 KEGG: 00680+1.2.7.12|MetaCyc: PWY-5209|MetaCyc: PWY-7784 TSH58p_01165 3a2cc15b96951714366192c9221af3b6 274 Pfam PF01493 GXGXG motif 142 208 8.6E-6 T 14-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 TSH58p_01165 3a2cc15b96951714366192c9221af3b6 274 SUPERFAMILY SSF69336 15 227 5.75E-31 T 14-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 TSH58p_01165 3a2cc15b96951714366192c9221af3b6 274 Gene3D G3DSA:2.160.20.60 140 221 3.6E-8 T 14-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 TSH58p_30540 a2d1a69f841161d2cd1487074474d4ba 644 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 242 638 1.8E-170 T 14-10-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 TSH58p_30540 a2d1a69f841161d2cd1487074474d4ba 644 SUPERFAMILY SSF53383 238 636 3.62E-125 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_30540 a2d1a69f841161d2cd1487074474d4ba 644 Gene3D G3DSA:3.40.640.10 270 530 1.6E-166 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_30540 a2d1a69f841161d2cd1487074474d4ba 644 Pfam PF00266 Aminotransferase class-V 259 628 3.9E-143 T 14-10-2018 IPR000192 Aminotransferase class V domain TSH58p_30540 a2d1a69f841161d2cd1487074474d4ba 644 Gene3D G3DSA:3.90.1150.10 243 632 1.6E-166 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_30540 a2d1a69f841161d2cd1487074474d4ba 644 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 451 470 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site TSH58p_10815 c9040c1234f89d85bbce1e04aece5622 253 SUPERFAMILY SSF52317 3 240 4.59E-41 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_10815 c9040c1234f89d85bbce1e04aece5622 253 Gene3D G3DSA:3.40.50.880 2 252 7.1E-66 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_10815 c9040c1234f89d85bbce1e04aece5622 253 Pfam PF07722 Peptidase C26 5 224 4.5E-72 T 14-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 TSH58p_18035 6a50327bc5ec05781fd3403271a61a91 770 Pfam PF14252 Domain of unknown function (DUF4347) 4 156 3.7E-30 T 14-10-2018 IPR025592 Domain of unknown function DUF4347 TSH58p_18035 6a50327bc5ec05781fd3403271a61a91 770 Gene3D G3DSA:2.150.10.10 130 244 2.2E-17 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_18035 6a50327bc5ec05781fd3403271a61a91 770 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 185 203 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_18035 6a50327bc5ec05781fd3403271a61a91 770 Gene3D G3DSA:2.150.10.10 306 454 3.7E-13 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_18035 6a50327bc5ec05781fd3403271a61a91 770 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 309 327 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_18035 6a50327bc5ec05781fd3403271a61a91 770 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 194 212 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_18035 6a50327bc5ec05781fd3403271a61a91 770 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 179 196 4.3E-4 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18035 6a50327bc5ec05781fd3403271a61a91 770 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 286 302 0.0012 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18035 6a50327bc5ec05781fd3403271a61a91 770 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 321 338 0.015 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18035 6a50327bc5ec05781fd3403271a61a91 770 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 197 212 0.19 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18035 6a50327bc5ec05781fd3403271a61a91 770 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 367 379 0.13 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18035 6a50327bc5ec05781fd3403271a61a91 770 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 651 668 0.037 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18035 6a50327bc5ec05781fd3403271a61a91 770 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 303 320 0.62 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18035 6a50327bc5ec05781fd3403271a61a91 770 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 270 284 0.028 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18035 6a50327bc5ec05781fd3403271a61a91 770 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 340 356 1.8 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18035 6a50327bc5ec05781fd3403271a61a91 770 SUPERFAMILY SSF51120 157 225 1.57E-13 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_18035 6a50327bc5ec05781fd3403271a61a91 770 SUPERFAMILY SSF51120 249 362 4.97E-23 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_18035 6a50327bc5ec05781fd3403271a61a91 770 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 318 336 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_18035 6a50327bc5ec05781fd3403271a61a91 770 PRINTS PR00313 NodO calcium binding signature 277 285 2.2E-12 T 14-10-2018 TSH58p_18035 6a50327bc5ec05781fd3403271a61a91 770 PRINTS PR00313 NodO calcium binding signature 372 381 2.2E-12 T 14-10-2018 TSH58p_18035 6a50327bc5ec05781fd3403271a61a91 770 PRINTS PR00313 NodO calcium binding signature 177 188 2.2E-12 T 14-10-2018 TSH58p_18035 6a50327bc5ec05781fd3403271a61a91 770 PRINTS PR00313 NodO calcium binding signature 331 339 2.2E-12 T 14-10-2018 TSH58p_18035 6a50327bc5ec05781fd3403271a61a91 770 SUPERFAMILY SSF51120 471 738 1.44E-20 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_18035 6a50327bc5ec05781fd3403271a61a91 770 Gene3D G3DSA:2.150.10.10 245 305 4.5E-12 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_18035 6a50327bc5ec05781fd3403271a61a91 770 Gene3D G3DSA:2.150.10.10 589 751 4.3E-13 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_28080 c415d7b61bb4ee522bb0bf33cc8126c7 384 Pfam PF03916 Polysulphide reductase, NrfD 47 329 3.3E-11 T 14-10-2018 IPR005614 NrfD family TSH58p_05620 672236ccafba54555d73f19cedd465c5 384 SUPERFAMILY SSF88713 161 377 1.62E-72 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TSH58p_05620 672236ccafba54555d73f19cedd465c5 384 Pfam PF04748 Divergent polysaccharide deacetylase 166 377 3.6E-80 T 14-10-2018 IPR006837 Divergent polysaccharide deacetylase TSH58p_05620 672236ccafba54555d73f19cedd465c5 384 Gene3D G3DSA:3.20.20.370 147 383 1.2E-91 T 14-10-2018 TSH58p_19840 40818a1ce4459da0b9f71a9842a44553 500 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 251 258 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 TSH58p_19840 40818a1ce4459da0b9f71a9842a44553 500 Gene3D G3DSA:3.40.309.10 255 449 1.4E-136 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TSH58p_19840 40818a1ce4459da0b9f71a9842a44553 500 Gene3D G3DSA:3.40.605.10 21 474 1.4E-136 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TSH58p_19840 40818a1ce4459da0b9f71a9842a44553 500 SUPERFAMILY SSF53720 17 485 2.36E-132 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSH58p_19840 40818a1ce4459da0b9f71a9842a44553 500 Pfam PF00171 Aldehyde dehydrogenase family 21 479 3.9E-124 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TSH58p_26320 2dcd60f625c266ebbecbd5446ad3b8c6 607 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 15 234 7.0E-106 T 14-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TSH58p_26320 2dcd60f625c266ebbecbd5446ad3b8c6 607 PIRSF PIRSF001348 1 601 8.9E-279 T 14-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TSH58p_26320 2dcd60f625c266ebbecbd5446ad3b8c6 607 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 3 598 50.481 T 14-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TSH58p_26320 2dcd60f625c266ebbecbd5446ad3b8c6 607 SUPERFAMILY SSF68923 4 237 7.85E-106 T 14-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 TSH58p_26320 2dcd60f625c266ebbecbd5446ad3b8c6 607 Gene3D G3DSA:3.40.449.10 14 237 1.3E-264 T 14-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 TSH58p_26320 2dcd60f625c266ebbecbd5446ad3b8c6 607 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 238 597 3.3E-167 T 14-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TSH58p_26320 2dcd60f625c266ebbecbd5446ad3b8c6 607 Gene3D G3DSA:3.90.228.20 238 590 1.3E-264 T 14-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 TSH58p_26320 2dcd60f625c266ebbecbd5446ad3b8c6 607 Gene3D G3DSA:2.170.8.10 50 393 1.3E-264 T 14-10-2018 TSH58p_26320 2dcd60f625c266ebbecbd5446ad3b8c6 607 SUPERFAMILY SSF53795 238 598 1.03E-155 T 14-10-2018 TSH58p_26320 2dcd60f625c266ebbecbd5446ad3b8c6 607 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 262 270 - T 14-10-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TSH58p_04155 79ecf6f29aef732abfaac0abb6ac1ffb 372 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 3.1E-83 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain TSH58p_04155 79ecf6f29aef732abfaac0abb6ac1ffb 372 SUPERFAMILY SSF52283 1 360 3.74E-67 T 14-10-2018 TSH58p_04155 79ecf6f29aef732abfaac0abb6ac1ffb 372 SMART SM01002 149 297 4.9E-88 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain TSH58p_04155 79ecf6f29aef732abfaac0abb6ac1ffb 372 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 8.5E-47 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal TSH58p_04155 79ecf6f29aef732abfaac0abb6ac1ffb 372 SMART SM01003 4 137 4.9E-78 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal TSH58p_04155 79ecf6f29aef732abfaac0abb6ac1ffb 372 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 4.0E-155 T 14-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 TSH58p_04155 79ecf6f29aef732abfaac0abb6ac1ffb 372 Gene3D G3DSA:3.40.50.720 130 305 2.4E-137 T 14-10-2018 TSH58p_04155 79ecf6f29aef732abfaac0abb6ac1ffb 372 PIRSF PIRSF000183 1 371 2.8E-154 T 14-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 TSH58p_04155 79ecf6f29aef732abfaac0abb6ac1ffb 372 SUPERFAMILY SSF51735 137 303 8.14E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_04155 79ecf6f29aef732abfaac0abb6ac1ffb 372 Gene3D G3DSA:3.40.50.720 3 353 2.4E-137 T 14-10-2018 TSH58p_01430 58aa2316a2186a0861cad9df456d07f3 467 Gene3D G3DSA:1.10.4100.10 3 312 2.0E-67 T 14-10-2018 TSH58p_01430 58aa2316a2186a0861cad9df456d07f3 467 Pfam PF03972 MmgE/PrpD family 15 396 4.3E-72 T 14-10-2018 IPR005656 MmgE/PrpD GO:0016829 TSH58p_01430 58aa2316a2186a0861cad9df456d07f3 467 SUPERFAMILY SSF103378 9 439 1.7E-76 T 14-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 TSH58p_29100 938857dd9c9a875a07f45f19ad20323b 394 Pfam PF02405 Permease MlaE 179 388 3.7E-72 T 14-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 TSH58p_29100 938857dd9c9a875a07f45f19ad20323b 394 SUPERFAMILY SSF52091 31 113 2.94E-8 T 14-10-2018 IPR036513 STAS domain superfamily TSH58p_29100 938857dd9c9a875a07f45f19ad20323b 394 Gene3D G3DSA:3.30.750.24 26 141 5.5E-7 T 14-10-2018 IPR036513 STAS domain superfamily TSH58p_29100 938857dd9c9a875a07f45f19ad20323b 394 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 158 390 1.1E-73 T 14-10-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria TSH58p_29100 938857dd9c9a875a07f45f19ad20323b 394 Pfam PF13466 STAS domain 40 113 1.4E-7 T 14-10-2018 IPR002645 STAS domain TSH58p_14925 9a1db2a7ec816259ea3302105d4eb85e 390 Gene3D G3DSA:3.20.20.500 1 383 3.2E-177 T 14-10-2018 TSH58p_14925 9a1db2a7ec816259ea3302105d4eb85e 390 SUPERFAMILY SSF51569 58 333 6.91E-11 T 14-10-2018 TSH58p_14925 9a1db2a7ec816259ea3302105d4eb85e 390 Pfam PF06187 Protein of unknown function (DUF993) 5 387 5.7E-189 T 14-10-2018 IPR009334 Protein of unknown function DUF993 TSH58p_14960 978e83b4829c980fbef2041d54624973 466 Pfam PF01546 Peptidase family M20/M25/M40 90 461 5.0E-33 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 TSH58p_14960 978e83b4829c980fbef2041d54624973 466 Gene3D G3DSA:3.40.630.10 24 455 1.8E-149 T 14-10-2018 TSH58p_14960 978e83b4829c980fbef2041d54624973 466 Gene3D G3DSA:3.30.70.360 213 383 1.8E-149 T 14-10-2018 TSH58p_14960 978e83b4829c980fbef2041d54624973 466 SUPERFAMILY SSF53187 9 464 5.71E-62 T 14-10-2018 TSH58p_14960 978e83b4829c980fbef2041d54624973 466 Pfam PF07687 Peptidase dimerisation domain 212 364 1.6E-23 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain TSH58p_01220 b917cd69f8c829ab4d790c8fa84cae13 173 SUPERFAMILY SSF54211 9 171 1.97E-69 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSH58p_01220 b917cd69f8c829ab4d790c8fa84cae13 173 Gene3D G3DSA:3.30.230.60 7 173 5.7E-76 T 14-10-2018 IPR037075 Formaldehyde-activating enzyme superfamily GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 TSH58p_01220 b917cd69f8c829ab4d790c8fa84cae13 173 Pfam PF08714 Formaldehyde-activating enzyme (Fae) 14 171 5.7E-73 T 14-10-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 TSH58p_01220 b917cd69f8c829ab4d790c8fa84cae13 173 TIGRFAM TIGR03126 one_C_fae: formaldehyde-activating enzyme 13 171 7.6E-77 T 14-10-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 TSH58p_26160 b7bd377d2313f02a1d5f8dbf003e7e3b 260 SUPERFAMILY SSF52540 14 238 2.66E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_26160 b7bd377d2313f02a1d5f8dbf003e7e3b 260 SMART SM00382 42 222 1.9E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_26160 b7bd377d2313f02a1d5f8dbf003e7e3b 260 Gene3D G3DSA:3.40.50.300 13 236 9.8E-64 T 14-10-2018 TSH58p_26160 b7bd377d2313f02a1d5f8dbf003e7e3b 260 Pfam PF00005 ABC transporter 33 171 9.8E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_26160 b7bd377d2313f02a1d5f8dbf003e7e3b 260 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_05345 739c57f26ac1a0b940aac3008e70dbae 175 SUPERFAMILY SSF52540 9 120 4.3E-16 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_05345 739c57f26ac1a0b940aac3008e70dbae 175 Pfam PF01745 Isopentenyl transferase 11 41 8.5E-5 T 14-10-2018 IPR002648 Adenylate dimethylallyltransferase GO:0004161|GO:0009058 KEGG: 00908+2.5.1.27|MetaCyc: PWY-2681 TSH58p_05345 739c57f26ac1a0b940aac3008e70dbae 175 Gene3D G3DSA:3.40.50.300 4 159 2.2E-11 T 14-10-2018 TSH58p_01285 2fff3c86bb0618ba281f0a3dcb4ffba0 1682 SUPERFAMILY SSF56112 56 274 2.37E-37 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily TSH58p_01285 2fff3c86bb0618ba281f0a3dcb4ffba0 1682 Pfam PF00069 Protein kinase domain 116 265 1.1E-17 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TSH58p_01285 2fff3c86bb0618ba281f0a3dcb4ffba0 1682 Gene3D G3DSA:3.30.565.10 1540 1680 1.5E-25 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_01285 2fff3c86bb0618ba281f0a3dcb4ffba0 1682 SUPERFAMILY SSF52540 299 565 2.06E-14 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_01285 2fff3c86bb0618ba281f0a3dcb4ffba0 1682 SUPERFAMILY SSF55781 1328 1477 4.8E-22 T 14-10-2018 TSH58p_01285 2fff3c86bb0618ba281f0a3dcb4ffba0 1682 Pfam PF07568 Histidine kinase 1483 1558 5.5E-26 T 14-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain TSH58p_01285 2fff3c86bb0618ba281f0a3dcb4ffba0 1682 Pfam PF13191 AAA ATPase domain 305 493 2.4E-35 T 14-10-2018 TSH58p_01285 2fff3c86bb0618ba281f0a3dcb4ffba0 1682 Gene3D G3DSA:1.10.510.10 106 278 7.9E-36 T 14-10-2018 TSH58p_01285 2fff3c86bb0618ba281f0a3dcb4ffba0 1682 SUPERFAMILY SSF55874 1546 1674 1.57E-13 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_01285 2fff3c86bb0618ba281f0a3dcb4ffba0 1682 Gene3D G3DSA:3.30.450.40 1312 1476 7.0E-26 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_01285 2fff3c86bb0618ba281f0a3dcb4ffba0 1682 SMART SM00065 1326 1479 1.1E-13 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_01285 2fff3c86bb0618ba281f0a3dcb4ffba0 1682 SMART SM00387 1579 1676 9.1E-6 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_01285 2fff3c86bb0618ba281f0a3dcb4ffba0 1682 Gene3D G3DSA:3.40.50.300 301 484 3.6E-5 T 14-10-2018 TSH58p_01285 2fff3c86bb0618ba281f0a3dcb4ffba0 1682 Pfam PF01590 GAF domain 1328 1469 5.4E-12 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_28465 e0080ce15ce1a9188be75ae4195eaddc 507 Pfam PF03572 Peptidase family S41 256 419 2.2E-43 T 14-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 TSH58p_28465 e0080ce15ce1a9188be75ae4195eaddc 507 Gene3D G3DSA:2.30.42.10 159 245 1.7E-72 T 14-10-2018 TSH58p_28465 e0080ce15ce1a9188be75ae4195eaddc 507 SMART SM00228 159 230 1.1E-12 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_28465 e0080ce15ce1a9188be75ae4195eaddc 507 Gene3D G3DSA:3.90.226.10 246 418 1.7E-72 T 14-10-2018 TSH58p_28465 e0080ce15ce1a9188be75ae4195eaddc 507 Gene3D G3DSA:3.30.750.44 120 397 1.7E-72 T 14-10-2018 TSH58p_28465 e0080ce15ce1a9188be75ae4195eaddc 507 SMART SM00245 231 422 3.4E-46 T 14-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 TSH58p_28465 e0080ce15ce1a9188be75ae4195eaddc 507 SUPERFAMILY SSF52096 115 423 4.97E-56 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_28465 e0080ce15ce1a9188be75ae4195eaddc 507 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 156 226 1.4E-8 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_28465 e0080ce15ce1a9188be75ae4195eaddc 507 SUPERFAMILY SSF50156 153 235 3.86E-17 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 TSH58p_28465 e0080ce15ce1a9188be75ae4195eaddc 507 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 118 421 1.3E-68 T 14-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 TSH58p_23390 7fc7a53a1f729943f12caa109251c7cc 691 Pfam PF05954 Phage late control gene D protein (GPD) 31 328 8.8E-85 T 14-10-2018 TSH58p_23390 7fc7a53a1f729943f12caa109251c7cc 691 SUPERFAMILY SSF69349 432 626 9.42E-43 T 14-10-2018 TSH58p_23390 7fc7a53a1f729943f12caa109251c7cc 691 Gene3D G3DSA:3.30.1920.30 229 287 8.2E-100 T 14-10-2018 TSH58p_23390 7fc7a53a1f729943f12caa109251c7cc 691 Gene3D G3DSA:3.55.50.10 103 194 8.2E-100 T 14-10-2018 TSH58p_23390 7fc7a53a1f729943f12caa109251c7cc 691 SUPERFAMILY SSF69279 200 349 7.31E-25 T 14-10-2018 TSH58p_23390 7fc7a53a1f729943f12caa109251c7cc 691 SUPERFAMILY SSF69255 354 442 9.94E-36 T 14-10-2018 TSH58p_23390 7fc7a53a1f729943f12caa109251c7cc 691 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 26 495 6.1E-129 T 14-10-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein TSH58p_23390 7fc7a53a1f729943f12caa109251c7cc 691 SUPERFAMILY SSF69279 13 189 8.08E-56 T 14-10-2018 TSH58p_23390 7fc7a53a1f729943f12caa109251c7cc 691 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 13 512 7.9E-179 T 14-10-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset TSH58p_23390 7fc7a53a1f729943f12caa109251c7cc 691 Gene3D G3DSA:2.40.50.230 345 447 4.1E-46 T 14-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily TSH58p_23390 7fc7a53a1f729943f12caa109251c7cc 691 Gene3D G3DSA:2.30.110.50 16 328 8.2E-100 T 14-10-2018 TSH58p_20825 61a3be4938b40896a8ca2beaa5ed7787 780 Gene3D G3DSA:3.40.50.720 666 757 5.4E-21 T 14-10-2018 TSH58p_20825 61a3be4938b40896a8ca2beaa5ed7787 780 Gene3D G3DSA:3.40.50.720 384 486 1.2E-31 T 14-10-2018 TSH58p_20825 61a3be4938b40896a8ca2beaa5ed7787 780 Pfam PF13450 NAD(P)-binding Rossmann-like domain 392 459 5.9E-15 T 14-10-2018 TSH58p_20825 61a3be4938b40896a8ca2beaa5ed7787 780 SUPERFAMILY SSF51971 388 749 1.07E-51 T 14-10-2018 TSH58p_20825 61a3be4938b40896a8ca2beaa5ed7787 780 Pfam PF03275 UDP-galactopyranose mutase 533 730 2.4E-81 T 14-10-2018 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 TSH58p_20825 61a3be4938b40896a8ca2beaa5ed7787 780 Gene3D G3DSA:3.40.50.2000 160 313 8.4E-33 T 14-10-2018 TSH58p_20825 61a3be4938b40896a8ca2beaa5ed7787 780 Pfam PF13692 Glycosyl transferases group 1 172 307 3.1E-12 T 14-10-2018 TSH58p_20825 61a3be4938b40896a8ca2beaa5ed7787 780 SUPERFAMILY SSF54373 632 697 2.94E-20 T 14-10-2018 TSH58p_20825 61a3be4938b40896a8ca2beaa5ed7787 780 SUPERFAMILY SSF53756 87 341 7.33E-19 T 14-10-2018 TSH58p_20825 61a3be4938b40896a8ca2beaa5ed7787 780 Gene3D G3DSA:3.40.50.720 538 652 1.7E-29 T 14-10-2018 TSH58p_20825 61a3be4938b40896a8ca2beaa5ed7787 780 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 388 744 8.9E-118 T 14-10-2018 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 TSH58p_24420 cded4830faef7ba7ce4b6edc348a7f17 333 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 185 0.0056 T 14-10-2018 TSH58p_24420 cded4830faef7ba7ce4b6edc348a7f17 333 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 241 1.2E-26 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TSH58p_24420 cded4830faef7ba7ce4b6edc348a7f17 333 Gene3D G3DSA:3.40.50.720 3 333 1.5E-87 T 14-10-2018 TSH58p_24420 cded4830faef7ba7ce4b6edc348a7f17 333 SUPERFAMILY SSF51735 4 331 3.72E-57 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_07375 b487114bd194dfbcef0c6c09b1eae190 370 PIRSF PIRSF005572 1 367 1.0E-112 T 14-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 TSH58p_07375 b487114bd194dfbcef0c6c09b1eae190 370 Gene3D G3DSA:1.10.260.50 15 266 2.9E-119 T 14-10-2018 TSH58p_07375 b487114bd194dfbcef0c6c09b1eae190 370 Gene3D G3DSA:3.90.1150.10 4 355 2.9E-119 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_07375 b487114bd194dfbcef0c6c09b1eae190 370 Pfam PF00266 Aminotransferase class-V 4 353 9.6E-61 T 14-10-2018 IPR000192 Aminotransferase class V domain TSH58p_07375 b487114bd194dfbcef0c6c09b1eae190 370 SUPERFAMILY SSF53383 3 356 5.79E-87 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_07375 b487114bd194dfbcef0c6c09b1eae190 370 Gene3D G3DSA:3.40.640.10 60 223 2.9E-119 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_28690 651aa8eb5794d05dc2e176782fdadc4e 262 Pfam PF00005 ABC transporter 37 185 1.6E-38 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_28690 651aa8eb5794d05dc2e176782fdadc4e 262 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_28690 651aa8eb5794d05dc2e176782fdadc4e 262 SMART SM00382 46 233 4.6E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_28690 651aa8eb5794d05dc2e176782fdadc4e 262 Gene3D G3DSA:3.40.50.300 18 261 3.0E-79 T 14-10-2018 TSH58p_28690 651aa8eb5794d05dc2e176782fdadc4e 262 PIRSF PIRSF039085 18 261 3.3E-110 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 TSH58p_28690 651aa8eb5794d05dc2e176782fdadc4e 262 SUPERFAMILY SSF52540 21 255 1.0E-81 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_15755 efd60d8fd99414e0ac31fd6f05a71f38 240 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 39 168 2.0E-6 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TSH58p_15755 efd60d8fd99414e0ac31fd6f05a71f38 240 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 208 224 - T 14-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 TSH58p_15755 efd60d8fd99414e0ac31fd6f05a71f38 240 SMART SM00478 43 206 4.1E-13 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TSH58p_15755 efd60d8fd99414e0ac31fd6f05a71f38 240 Gene3D G3DSA:1.10.340.30 28 148 1.5E-58 T 14-10-2018 TSH58p_15755 efd60d8fd99414e0ac31fd6f05a71f38 240 PIRSF PIRSF001435 6 232 1.0E-36 T 14-10-2018 TSH58p_15755 efd60d8fd99414e0ac31fd6f05a71f38 240 SUPERFAMILY SSF48150 13 227 7.07E-43 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TSH58p_15755 efd60d8fd99414e0ac31fd6f05a71f38 240 Gene3D G3DSA:1.10.1670.10 10 224 1.5E-58 T 14-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 TSH58p_01535 bb8d510ed361c9d947d99b2697f01c4c 192 SUPERFAMILY SSF51182 66 192 9.62E-28 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_01535 bb8d510ed361c9d947d99b2697f01c4c 192 Gene3D G3DSA:1.10.260.40 6 77 2.0E-17 T 14-10-2018 TSH58p_01535 bb8d510ed361c9d947d99b2697f01c4c 192 SUPERFAMILY SSF47413 4 73 3.1E-16 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_01535 bb8d510ed361c9d947d99b2697f01c4c 192 Pfam PF07883 Cupin domain 119 186 1.2E-18 T 14-10-2018 IPR013096 Cupin 2, conserved barrel TSH58p_01535 bb8d510ed361c9d947d99b2697f01c4c 192 Gene3D G3DSA:2.60.120.10 78 189 2.8E-20 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_01535 bb8d510ed361c9d947d99b2697f01c4c 192 SMART SM00530 14 69 2.2E-11 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_01535 bb8d510ed361c9d947d99b2697f01c4c 192 Pfam PF13560 Helix-turn-helix domain 11 65 2.0E-11 T 14-10-2018 TSH58p_14790 45715d39c5efa223397d7602990a89a7 438 Pfam PF01435 Peptidase family M48 32 219 1.5E-29 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 TSH58p_14790 45715d39c5efa223397d7602990a89a7 438 Gene3D G3DSA:1.25.40.10 228 435 6.1E-15 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_14790 45715d39c5efa223397d7602990a89a7 438 Gene3D G3DSA:3.30.2010.10 22 107 1.7E-7 T 14-10-2018 TSH58p_14790 45715d39c5efa223397d7602990a89a7 438 SUPERFAMILY SSF48452 260 392 1.48E-14 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_10920 81eda741968879be64c530b4c338ee16 453 Gene3D G3DSA:2.120.10.30 54 432 8.6E-15 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TSH58p_10920 81eda741968879be64c530b4c338ee16 453 Pfam PF07995 Glucose / Sorbosone dehydrogenase 161 354 6.0E-10 T 14-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase TSH58p_10920 81eda741968879be64c530b4c338ee16 453 SUPERFAMILY SSF50952 59 428 8.37E-42 T 14-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 TSH58p_16280 aaa2b82a48fdee2c849922134abe41c0 351 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 122 141 8.7E-31 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TSH58p_16280 aaa2b82a48fdee2c849922134abe41c0 351 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 98 114 8.7E-31 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TSH58p_16280 aaa2b82a48fdee2c849922134abe41c0 351 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 153 165 8.7E-31 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TSH58p_16280 aaa2b82a48fdee2c849922134abe41c0 351 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 19 32 8.7E-31 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TSH58p_16280 aaa2b82a48fdee2c849922134abe41c0 351 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 76 92 8.7E-31 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TSH58p_16280 aaa2b82a48fdee2c849922134abe41c0 351 Gene3D G3DSA:3.40.960.10 239 338 1.5E-29 T 14-10-2018 TSH58p_16280 aaa2b82a48fdee2c849922134abe41c0 351 Gene3D G3DSA:3.30.420.10 18 173 1.5E-45 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TSH58p_16280 aaa2b82a48fdee2c849922134abe41c0 351 Pfam PF04480 Protein of unknown function (DUF559) 230 334 1.5E-35 T 14-10-2018 IPR007569 Protein of unknown function DUF559 TSH58p_16280 aaa2b82a48fdee2c849922134abe41c0 351 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 16 168 45.662 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TSH58p_16280 aaa2b82a48fdee2c849922134abe41c0 351 SUPERFAMILY SSF52980 227 336 2.31E-21 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TSH58p_16280 aaa2b82a48fdee2c849922134abe41c0 351 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 18 171 2.0E-43 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TSH58p_16280 aaa2b82a48fdee2c849922134abe41c0 351 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 19 165 2.0E-43 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TSH58p_16280 aaa2b82a48fdee2c849922134abe41c0 351 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 128 162 - T 14-10-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 TSH58p_16280 aaa2b82a48fdee2c849922134abe41c0 351 SUPERFAMILY SSF53098 17 172 3.41E-49 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily TSH58p_08645 acdba37c4bd95816e0133a2cf669b21c 495 SUPERFAMILY SSF53383 120 491 2.33E-82 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_08645 acdba37c4bd95816e0133a2cf669b21c 495 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 87 9.8E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_08645 acdba37c4bd95816e0133a2cf669b21c 495 SMART SM00345 28 87 8.2E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_08645 acdba37c4bd95816e0133a2cf669b21c 495 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 61 5.5E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_08645 acdba37c4bd95816e0133a2cf669b21c 495 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 61 77 5.5E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_08645 acdba37c4bd95816e0133a2cf669b21c 495 SUPERFAMILY SSF46785 19 94 6.95E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_08645 acdba37c4bd95816e0133a2cf669b21c 495 Pfam PF00155 Aminotransferase class I and II 167 410 4.7E-18 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSH58p_08645 acdba37c4bd95816e0133a2cf669b21c 495 Gene3D G3DSA:3.40.640.10 127 485 1.1E-111 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_08645 acdba37c4bd95816e0133a2cf669b21c 495 Gene3D G3DSA:1.10.10.10 15 96 6.7E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_09895 f850c24e102e3e3575b83a4f1d41e95c 442 Gene3D G3DSA:1.10.940.10 4 144 4.9E-33 T 14-10-2018 IPR035926 NusB-like superfamily TSH58p_09895 f850c24e102e3e3575b83a4f1d41e95c 442 SUPERFAMILY SSF53335 145 439 4.22E-60 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_09895 f850c24e102e3e3575b83a4f1d41e95c 442 SUPERFAMILY SSF48013 8 149 2.29E-29 T 14-10-2018 IPR035926 NusB-like superfamily TSH58p_09895 f850c24e102e3e3575b83a4f1d41e95c 442 Gene3D G3DSA:3.40.50.150 151 439 2.0E-64 T 14-10-2018 TSH58p_09895 f850c24e102e3e3575b83a4f1d41e95c 442 Pfam PF01029 NusB family 8 127 8.0E-22 T 14-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 TSH58p_09895 f850c24e102e3e3575b83a4f1d41e95c 442 Pfam PF01189 16S rRNA methyltransferase RsmB/F 241 438 1.0E-47 T 14-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 TSH58p_09895 f850c24e102e3e3575b83a4f1d41e95c 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 422 439 8.3E-26 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSH58p_09895 f850c24e102e3e3575b83a4f1d41e95c 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 353 369 8.3E-26 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSH58p_09895 f850c24e102e3e3575b83a4f1d41e95c 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 213 227 8.3E-26 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSH58p_09895 f850c24e102e3e3575b83a4f1d41e95c 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 242 252 8.3E-26 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSH58p_09895 f850c24e102e3e3575b83a4f1d41e95c 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 303 315 8.3E-26 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSH58p_28140 02eb60025af6c2a29958780e4d5cf29a 233 Gene3D G3DSA:3.40.30.10 2 203 1.7E-80 T 14-10-2018 TSH58p_28140 02eb60025af6c2a29958780e4d5cf29a 233 Gene3D G3DSA:1.20.1050.10 88 196 1.7E-80 T 14-10-2018 TSH58p_28140 02eb60025af6c2a29958780e4d5cf29a 233 SUPERFAMILY SSF47616 78 206 3.55E-37 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily TSH58p_28140 02eb60025af6c2a29958780e4d5cf29a 233 Pfam PF00043 Glutathione S-transferase, C-terminal domain 131 197 9.0E-12 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal TSH58p_28140 02eb60025af6c2a29958780e4d5cf29a 233 SUPERFAMILY SSF52833 1 84 3.28E-22 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_28140 02eb60025af6c2a29958780e4d5cf29a 233 Pfam PF02798 Glutathione S-transferase, N-terminal domain 5 81 1.4E-13 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 TSH58p_01065 acfd0f0257631243424852c046343fcd 466 SUPERFAMILY SSF52141 292 455 1.01E-43 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSH58p_01065 acfd0f0257631243424852c046343fcd 466 TIGRFAM TIGR03915 SAM_7_link_chp: probable DNA metabolism protein 10 235 2.3E-60 T 14-10-2018 IPR023875 DNA metabolism protein, putative TSH58p_01065 acfd0f0257631243424852c046343fcd 466 SMART SM00987 302 460 1.9E-35 T 14-10-2018 TSH58p_01065 acfd0f0257631243424852c046343fcd 466 Pfam PF03167 Uracil DNA glycosylase superfamily 303 460 2.1E-33 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSH58p_01065 acfd0f0257631243424852c046343fcd 466 Gene3D G3DSA:3.40.470.10 278 466 4.7E-47 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSH58p_01065 acfd0f0257631243424852c046343fcd 466 SMART SM00986 302 460 1.9E-35 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSH58p_01065 acfd0f0257631243424852c046343fcd 466 TIGRFAM TIGR03914 UDG_fam_dom: uracil-DNA glycosylase family domain 238 461 4.8E-88 T 14-10-2018 IPR005273 Uracil-DNA glycosylase family 4 TSH58p_01065 acfd0f0257631243424852c046343fcd 466 Pfam PF13566 Domain of unknown function (DUF4130 74 234 2.7E-42 T 14-10-2018 IPR025404 Domain of unknown function DUF4130 TSH58p_29195 62b04529dad150616004f3b145fa8bef 252 Gene3D G3DSA:3.90.550.10 9 217 2.4E-31 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_29195 62b04529dad150616004f3b145fa8bef 252 Pfam PF02348 Cytidylyltransferase 11 182 2.4E-21 T 14-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 TSH58p_29195 62b04529dad150616004f3b145fa8bef 252 SUPERFAMILY SSF53448 10 218 2.15E-26 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_24255 1b07dba12255185e8bbbfe0e20fa32b8 249 SUPERFAMILY SSF52402 1 242 6.58E-89 T 14-10-2018 TSH58p_24255 1b07dba12255185e8bbbfe0e20fa32b8 249 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 14-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 TSH58p_24255 1b07dba12255185e8bbbfe0e20fa32b8 249 PIRSF PIRSF000090 1 249 5.1E-90 T 14-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 TSH58p_24255 1b07dba12255185e8bbbfe0e20fa32b8 249 Pfam PF01012 Electron transfer flavoprotein domain 26 206 2.1E-51 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 TSH58p_24255 1b07dba12255185e8bbbfe0e20fa32b8 249 SMART SM00893 23 211 1.7E-72 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 TSH58p_24255 1b07dba12255185e8bbbfe0e20fa32b8 249 Gene3D G3DSA:3.40.50.620 1 247 1.7E-91 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_10755 ef8399b7ce7d5598b25d2178899b2c36 205 Pfam PF01470 Pyroglutamyl peptidase 5 191 3.1E-48 T 14-10-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like MetaCyc: PWY-7942 TSH58p_10755 ef8399b7ce7d5598b25d2178899b2c36 205 Gene3D G3DSA:3.40.630.20 3 200 1.4E-60 T 14-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 TSH58p_10755 ef8399b7ce7d5598b25d2178899b2c36 205 SUPERFAMILY SSF53182 5 197 4.97E-54 T 14-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 TSH58p_10755 ef8399b7ce7d5598b25d2178899b2c36 205 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 77 97 7.7E-24 T 14-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TSH58p_10755 ef8399b7ce7d5598b25d2178899b2c36 205 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 129 145 7.7E-24 T 14-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TSH58p_10755 ef8399b7ce7d5598b25d2178899b2c36 205 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 5 28 7.7E-24 T 14-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TSH58p_10755 ef8399b7ce7d5598b25d2178899b2c36 205 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 159 171 7.7E-24 T 14-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TSH58p_10755 ef8399b7ce7d5598b25d2178899b2c36 205 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 59 71 7.7E-24 T 14-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TSH58p_10755 ef8399b7ce7d5598b25d2178899b2c36 205 PIRSF PIRSF015592 2 199 1.1E-54 T 14-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TSH58p_04085 c5fb7a43cdc0921f2225f6e510a07266 291 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 4 286 5.0E-103 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSH58p_04085 c5fb7a43cdc0921f2225f6e510a07266 291 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 132 162 - T 14-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 TSH58p_04085 c5fb7a43cdc0921f2225f6e510a07266 291 SMART SM01130 1 288 3.9E-148 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_04085 c5fb7a43cdc0921f2225f6e510a07266 291 PIRSF PIRSF001365 1 291 9.4E-93 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_04085 c5fb7a43cdc0921f2225f6e510a07266 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 34 55 8.1E-37 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_04085 c5fb7a43cdc0921f2225f6e510a07266 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 127 144 8.1E-37 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_04085 c5fb7a43cdc0921f2225f6e510a07266 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 102 118 8.1E-37 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_04085 c5fb7a43cdc0921f2225f6e510a07266 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 70 88 8.1E-37 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_04085 c5fb7a43cdc0921f2225f6e510a07266 291 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 37 54 - T 14-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSH58p_04085 c5fb7a43cdc0921f2225f6e510a07266 291 SUPERFAMILY SSF51569 2 288 1.67E-107 T 14-10-2018 TSH58p_04085 c5fb7a43cdc0921f2225f6e510a07266 291 Gene3D G3DSA:3.20.20.70 1 290 1.6E-113 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_04085 c5fb7a43cdc0921f2225f6e510a07266 291 Pfam PF00701 Dihydrodipicolinate synthetase family 3 286 3.2E-97 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_04085 c5fb7a43cdc0921f2225f6e510a07266 291 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 286 66.642 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSH58p_32495 ae70cb336e8af72e294d2ec69eed858d 577 Pfam PF07568 Histidine kinase 378 452 3.2E-19 T 14-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain TSH58p_32495 ae70cb336e8af72e294d2ec69eed858d 577 Pfam PF02743 Cache domain 36 272 1.0E-14 T 14-10-2018 IPR033479 Double Cache domain 1 TSH58p_32495 ae70cb336e8af72e294d2ec69eed858d 577 SUPERFAMILY SSF55874 442 564 1.2E-16 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_32495 ae70cb336e8af72e294d2ec69eed858d 577 Gene3D G3DSA:3.30.565.10 436 572 1.1E-28 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_32495 ae70cb336e8af72e294d2ec69eed858d 577 Pfam PF13581 Histidine kinase-like ATPase domain 468 530 3.2E-8 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_32495 ae70cb336e8af72e294d2ec69eed858d 577 Gene3D G3DSA:3.30.450.20 347 431 2.4E-7 T 14-10-2018 TSH58p_32495 ae70cb336e8af72e294d2ec69eed858d 577 SMART SM00387 473 567 1.4E-9 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_32495 ae70cb336e8af72e294d2ec69eed858d 577 Gene3D G3DSA:3.30.450.20 81 184 2.7E-16 T 14-10-2018 TSH58p_23845 a3fc626497c686f465f6651d1f782869 246 SMART SM00363 4 66 2.4E-5 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_23845 a3fc626497c686f465f6651d1f782869 246 SUPERFAMILY SSF55174 4 69 1.12E-9 T 14-10-2018 TSH58p_23845 a3fc626497c686f465f6651d1f782869 246 Pfam PF01479 S4 domain 5 43 1.5E-7 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_23845 a3fc626497c686f465f6651d1f782869 246 Gene3D G3DSA:3.10.290.10 1 62 1.1E-21 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TSH58p_23845 a3fc626497c686f465f6651d1f782869 246 SUPERFAMILY SSF53335 59 241 1.73E-27 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_23845 a3fc626497c686f465f6651d1f782869 246 Pfam PF01728 FtsJ-like methyltransferase 60 241 2.3E-23 T 14-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 TSH58p_23845 a3fc626497c686f465f6651d1f782869 246 PIRSF PIRSF005578 1 246 4.7E-99 T 14-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 TSH58p_23845 a3fc626497c686f465f6651d1f782869 246 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 5 237 3.8E-67 T 14-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 TSH58p_23845 a3fc626497c686f465f6651d1f782869 246 Gene3D G3DSA:3.40.50.150 63 245 4.6E-74 T 14-10-2018 TSH58p_28550 a5ec2070e4284835b11dc4775014ba2a 356 Gene3D G3DSA:3.40.50.2300 41 167 3.2E-11 T 14-10-2018 TSH58p_28550 a5ec2070e4284835b11dc4775014ba2a 356 SMART SM00448 43 155 4.7E-4 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_28550 a5ec2070e4284835b11dc4775014ba2a 356 SUPERFAMILY SSF46785 284 351 2.12E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_28550 a5ec2070e4284835b11dc4775014ba2a 356 Pfam PF00072 Response regulator receiver domain 45 155 1.6E-8 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_28550 a5ec2070e4284835b11dc4775014ba2a 356 Pfam PF13463 Winged helix DNA-binding domain 284 341 5.6E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_28550 a5ec2070e4284835b11dc4775014ba2a 356 SUPERFAMILY SSF52172 43 161 1.05E-13 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_28550 a5ec2070e4284835b11dc4775014ba2a 356 Gene3D G3DSA:1.10.10.10 250 353 8.7E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_11000 d077d14fe13b355c23c39417133216a6 305 Gene3D G3DSA:1.10.10.2830 121 231 3.8E-40 T 14-10-2018 TSH58p_11000 d077d14fe13b355c23c39417133216a6 305 SMART SM00470 42 134 8.0E-34 T 14-10-2018 IPR003115 ParB/Sulfiredoxin TSH58p_11000 d077d14fe13b355c23c39417133216a6 305 Gene3D G3DSA:3.90.1530.30 55 120 1.3E-27 T 14-10-2018 TSH58p_11000 d077d14fe13b355c23c39417133216a6 305 Pfam PF02195 ParB-like nuclease domain 43 134 4.5E-26 T 14-10-2018 IPR003115 ParB/Sulfiredoxin TSH58p_11000 d077d14fe13b355c23c39417133216a6 305 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 40 207 4.0E-61 T 14-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 TSH58p_11000 d077d14fe13b355c23c39417133216a6 305 SUPERFAMILY SSF109709 126 231 1.44E-33 T 14-10-2018 TSH58p_11000 d077d14fe13b355c23c39417133216a6 305 SUPERFAMILY SSF110849 43 136 2.62E-28 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily TSH58p_29690 6eba8e3a81df356a759c9201f0d393d6 151 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 136 4.6E-25 T 14-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 TSH58p_29690 6eba8e3a81df356a759c9201f0d393d6 151 SUPERFAMILY SSF56214 1 134 4.19E-25 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TSH58p_29690 6eba8e3a81df356a759c9201f0d393d6 151 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 1 136 1.3E-20 T 14-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 TSH58p_29690 6eba8e3a81df356a759c9201f0d393d6 151 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 106 5.0E-34 T 14-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 TSH58p_29690 6eba8e3a81df356a759c9201f0d393d6 151 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 136 24.105 T 14-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 TSH58p_29690 6eba8e3a81df356a759c9201f0d393d6 151 Gene3D G3DSA:3.90.470.20 1 145 3.0E-31 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TSH58p_29690 6eba8e3a81df356a759c9201f0d393d6 151 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 102 5.1E-17 T 14-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TSH58p_04990 edcfcf037c74688aefd5f9209f3691b0 283 Hamap MF_00258 Glutamate racemase [murI]. 1 275 28.119 T 14-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TSH58p_04990 edcfcf037c74688aefd5f9209f3691b0 283 Pfam PF01177 Asp/Glu/Hydantoin racemase 2 230 1.8E-25 T 14-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TSH58p_04990 edcfcf037c74688aefd5f9209f3691b0 283 Gene3D G3DSA:3.40.50.1860 97 224 7.8E-78 T 14-10-2018 TSH58p_04990 edcfcf037c74688aefd5f9209f3691b0 283 SUPERFAMILY SSF53681 124 279 6.98E-29 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TSH58p_04990 edcfcf037c74688aefd5f9209f3691b0 283 TIGRFAM TIGR00067 glut_race: glutamate racemase 2 262 4.8E-45 T 14-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TSH58p_04990 edcfcf037c74688aefd5f9209f3691b0 283 SUPERFAMILY SSF53681 2 106 3.14E-26 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TSH58p_04990 edcfcf037c74688aefd5f9209f3691b0 283 Gene3D G3DSA:3.40.50.1860 2 273 7.8E-78 T 14-10-2018 TSH58p_30550 81484b8e2553b8b745bedc9f2d629bd0 543 Hamap MF_00600 60 kDa chaperonin [groL]. 2 541 41.704 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TSH58p_30550 81484b8e2553b8b745bedc9f2d629bd0 543 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 527 4.3E-253 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TSH58p_30550 81484b8e2553b8b745bedc9f2d629bd0 543 Gene3D G3DSA:1.10.560.10 7 522 8.7E-233 T 14-10-2018 IPR027413 GroEL-like equatorial domain superfamily TSH58p_30550 81484b8e2553b8b745bedc9f2d629bd0 543 PRINTS PR00298 60kDa chaperonin signature 268 291 6.6E-73 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TSH58p_30550 81484b8e2553b8b745bedc9f2d629bd0 543 PRINTS PR00298 60kDa chaperonin signature 398 419 6.6E-73 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TSH58p_30550 81484b8e2553b8b745bedc9f2d629bd0 543 PRINTS PR00298 60kDa chaperonin signature 27 53 6.6E-73 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TSH58p_30550 81484b8e2553b8b745bedc9f2d629bd0 543 PRINTS PR00298 60kDa chaperonin signature 83 110 6.6E-73 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TSH58p_30550 81484b8e2553b8b745bedc9f2d629bd0 543 PRINTS PR00298 60kDa chaperonin signature 350 375 6.6E-73 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TSH58p_30550 81484b8e2553b8b745bedc9f2d629bd0 543 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 525 1.1E-98 T 14-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 TSH58p_30550 81484b8e2553b8b745bedc9f2d629bd0 543 Gene3D G3DSA:3.50.7.10 192 373 8.7E-233 T 14-10-2018 IPR027409 GroEL-like apical domain superfamily TSH58p_30550 81484b8e2553b8b745bedc9f2d629bd0 543 SUPERFAMILY SSF54849 138 203 3.2E-21 T 14-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TSH58p_30550 81484b8e2553b8b745bedc9f2d629bd0 543 SUPERFAMILY SSF48592 7 522 3.66E-74 T 14-10-2018 IPR027413 GroEL-like equatorial domain superfamily TSH58p_30550 81484b8e2553b8b745bedc9f2d629bd0 543 Gene3D G3DSA:3.30.260.10 137 410 8.7E-233 T 14-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TSH58p_30550 81484b8e2553b8b745bedc9f2d629bd0 543 SUPERFAMILY SSF52029 184 376 5.06E-83 T 14-10-2018 IPR027409 GroEL-like apical domain superfamily TSH58p_16355 0d5a04f03575986cc09d991a170101d8 327 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 253 1.6E-54 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TSH58p_16355 0d5a04f03575986cc09d991a170101d8 327 SUPERFAMILY SSF51735 1 324 2.63E-89 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_16355 0d5a04f03575986cc09d991a170101d8 327 PRINTS PR01713 Nucleotide sugar epimerase signature 218 233 2.8E-22 T 14-10-2018 TSH58p_16355 0d5a04f03575986cc09d991a170101d8 327 PRINTS PR01713 Nucleotide sugar epimerase signature 247 262 2.8E-22 T 14-10-2018 TSH58p_16355 0d5a04f03575986cc09d991a170101d8 327 PRINTS PR01713 Nucleotide sugar epimerase signature 29 45 2.8E-22 T 14-10-2018 TSH58p_16355 0d5a04f03575986cc09d991a170101d8 327 PRINTS PR01713 Nucleotide sugar epimerase signature 286 303 2.8E-22 T 14-10-2018 TSH58p_16355 0d5a04f03575986cc09d991a170101d8 327 Gene3D G3DSA:3.40.50.720 1 325 1.2E-94 T 14-10-2018 TSH58p_09905 2995052229bcb9fb903d73e88f13c28f 310 SUPERFAMILY SSF64182 9 304 2.09E-7 T 14-10-2018 IPR038763 DHH phosphoesterase superfamily TSH58p_09905 2995052229bcb9fb903d73e88f13c28f 310 PIRSF PIRSF028235 1 310 5.6E-149 T 14-10-2018 IPR016877 Uncharacterised conserved protein UCP028235 TSH58p_29485 c365c75e07008ba4e27b78920db39b8b 597 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_29485 c365c75e07008ba4e27b78920db39b8b 597 SUPERFAMILY SSF90123 21 338 3.66E-69 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_29485 c365c75e07008ba4e27b78920db39b8b 597 SMART SM00382 375 561 1.1E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_29485 c365c75e07008ba4e27b78920db39b8b 597 Pfam PF00664 ABC transporter transmembrane region 35 291 2.6E-42 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TSH58p_29485 c365c75e07008ba4e27b78920db39b8b 597 Gene3D G3DSA:1.20.1560.10 8 336 1.6E-73 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_29485 c365c75e07008ba4e27b78920db39b8b 597 Gene3D G3DSA:3.40.50.300 341 593 2.4E-92 T 14-10-2018 TSH58p_29485 c365c75e07008ba4e27b78920db39b8b 597 Pfam PF00005 ABC transporter 366 515 3.0E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_29485 c365c75e07008ba4e27b78920db39b8b 597 SUPERFAMILY SSF52540 341 586 3.91E-91 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_03210 9f984e09497ee3500374d9b72cccfe14 390 Gene3D G3DSA:3.40.630.10 16 371 2.7E-139 T 14-10-2018 TSH58p_03210 9f984e09497ee3500374d9b72cccfe14 390 Pfam PF01546 Peptidase family M20/M25/M40 72 383 3.5E-38 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 TSH58p_03210 9f984e09497ee3500374d9b72cccfe14 390 PIRSF PIRSF005962 2 389 1.5E-130 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 TSH58p_03210 9f984e09497ee3500374d9b72cccfe14 390 Gene3D G3DSA:3.30.70.360 181 295 2.7E-139 T 14-10-2018 TSH58p_03210 9f984e09497ee3500374d9b72cccfe14 390 SUPERFAMILY SSF53187 6 386 1.83E-88 T 14-10-2018 TSH58p_03210 9f984e09497ee3500374d9b72cccfe14 390 Pfam PF07687 Peptidase dimerisation domain 186 279 4.8E-6 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain TSH58p_03210 9f984e09497ee3500374d9b72cccfe14 390 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 15 374 2.0E-111 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 TSH58p_03210 9f984e09497ee3500374d9b72cccfe14 390 SUPERFAMILY SSF55031 184 296 2.22E-28 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TSH58p_06440 65cd22611c9c7ce7037ae94f73b80ad9 140 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 58 101 - T 14-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 TSH58p_06440 65cd22611c9c7ce7037ae94f73b80ad9 140 SUPERFAMILY SSF53927 8 138 1.02E-43 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TSH58p_06440 65cd22611c9c7ce7037ae94f73b80ad9 140 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 8 105 1.3E-12 T 14-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain TSH58p_06440 65cd22611c9c7ce7037ae94f73b80ad9 140 Gene3D G3DSA:3.40.140.10 3 139 3.8E-48 T 14-10-2018 TSH58p_06440 65cd22611c9c7ce7037ae94f73b80ad9 140 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 11 137 4.9E-43 T 14-10-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 TSH58p_10600 c4946f5b57258f43c69acad5b6285436 121 Pfam PF00072 Response regulator receiver domain 5 116 1.0E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_10600 c4946f5b57258f43c69acad5b6285436 121 Gene3D G3DSA:3.40.50.12740 2 120 2.5E-37 T 14-10-2018 TSH58p_10600 c4946f5b57258f43c69acad5b6285436 121 SMART SM00448 3 116 8.8E-39 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_10600 c4946f5b57258f43c69acad5b6285436 121 SUPERFAMILY SSF52172 3 120 6.12E-37 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_13970 7d293f97d732c902831313c075b93b04 542 SUPERFAMILY SSF52172 420 538 9.82E-24 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_13970 7d293f97d732c902831313c075b93b04 542 Pfam PF00512 His Kinase A (phospho-acceptor) domain 180 244 1.4E-6 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_13970 7d293f97d732c902831313c075b93b04 542 SUPERFAMILY SSF55785 41 137 1.2E-12 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_13970 7d293f97d732c902831313c075b93b04 542 Gene3D G3DSA:1.10.287.130 147 242 6.8E-14 T 14-10-2018 TSH58p_13970 7d293f97d732c902831313c075b93b04 542 SUPERFAMILY SSF55874 234 399 6.81E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_13970 7d293f97d732c902831313c075b93b04 542 Gene3D G3DSA:3.30.565.10 250 402 2.6E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_13970 7d293f97d732c902831313c075b93b04 542 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 289 397 9.5E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_13970 7d293f97d732c902831313c075b93b04 542 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 41 147 1.8E-9 T 14-10-2018 IPR000014 PAS domain TSH58p_13970 7d293f97d732c902831313c075b93b04 542 SUPERFAMILY SSF47384 165 244 6.47E-11 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_13970 7d293f97d732c902831313c075b93b04 542 SMART SM00091 39 106 3.4E-5 T 14-10-2018 IPR000014 PAS domain TSH58p_13970 7d293f97d732c902831313c075b93b04 542 Pfam PF00072 Response regulator receiver domain 421 532 1.9E-13 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_13970 7d293f97d732c902831313c075b93b04 542 Pfam PF08448 PAS fold 45 146 2.6E-10 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_13970 7d293f97d732c902831313c075b93b04 542 PRINTS PR00344 Bacterial sensor protein C-terminal signature 342 352 5.7E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_13970 7d293f97d732c902831313c075b93b04 542 PRINTS PR00344 Bacterial sensor protein C-terminal signature 324 338 5.7E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_13970 7d293f97d732c902831313c075b93b04 542 PRINTS PR00344 Bacterial sensor protein C-terminal signature 359 377 5.7E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_13970 7d293f97d732c902831313c075b93b04 542 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 396 5.7E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_13970 7d293f97d732c902831313c075b93b04 542 Gene3D G3DSA:3.30.450.20 35 146 2.2E-12 T 14-10-2018 TSH58p_13970 7d293f97d732c902831313c075b93b04 542 Gene3D G3DSA:3.40.50.2300 416 542 9.8E-23 T 14-10-2018 TSH58p_13970 7d293f97d732c902831313c075b93b04 542 SMART SM00388 179 244 4.2E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_13970 7d293f97d732c902831313c075b93b04 542 SMART SM00387 288 399 1.7E-30 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_13970 7d293f97d732c902831313c075b93b04 542 SMART SM00448 418 532 1.8E-18 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_16810 c172defb14d561f9d7bbed01be4804da 277 Gene3D G3DSA:3.40.190.10 77 275 1.9E-12 T 14-10-2018 TSH58p_16810 c172defb14d561f9d7bbed01be4804da 277 Gene3D G3DSA:3.40.190.10 154 248 1.9E-12 T 14-10-2018 TSH58p_16810 c172defb14d561f9d7bbed01be4804da 277 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 72 261 4.6E-8 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_16810 c172defb14d561f9d7bbed01be4804da 277 SUPERFAMILY SSF53850 69 268 1.03E-17 T 14-10-2018 TSH58p_00680 09ba9a973036ab1fe2fbc493611adfc2 446 Gene3D G3DSA:1.10.580.10 73 428 3.8E-144 T 14-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 TSH58p_00680 09ba9a973036ab1fe2fbc493611adfc2 446 Gene3D G3DSA:2.20.28.60 13 66 3.3E-17 T 14-10-2018 TSH58p_00680 09ba9a973036ab1fe2fbc493611adfc2 446 Pfam PF00285 Citrate synthase, C-terminal domain 62 428 4.3E-131 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 TSH58p_00680 09ba9a973036ab1fe2fbc493611adfc2 446 PRINTS PR00143 Citrate synthase signature 235 250 2.0E-56 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 TSH58p_00680 09ba9a973036ab1fe2fbc493611adfc2 446 PRINTS PR00143 Citrate synthase signature 396 410 2.0E-56 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 TSH58p_00680 09ba9a973036ab1fe2fbc493611adfc2 446 PRINTS PR00143 Citrate synthase signature 181 194 2.0E-56 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 TSH58p_00680 09ba9a973036ab1fe2fbc493611adfc2 446 PRINTS PR00143 Citrate synthase signature 257 285 2.0E-56 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 TSH58p_00680 09ba9a973036ab1fe2fbc493611adfc2 446 PRINTS PR00143 Citrate synthase signature 376 392 2.0E-56 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 TSH58p_00680 09ba9a973036ab1fe2fbc493611adfc2 446 PRINTS PR00143 Citrate synthase signature 312 332 2.0E-56 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 TSH58p_00680 09ba9a973036ab1fe2fbc493611adfc2 446 PIRSF PIRSF001369 53 446 3.2E-169 T 14-10-2018 IPR024176 Citrate synthase, bacterial-type TSH58p_00680 09ba9a973036ab1fe2fbc493611adfc2 446 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 30 438 2.6E-235 T 14-10-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 TSH58p_00680 09ba9a973036ab1fe2fbc493611adfc2 446 Gene3D G3DSA:1.10.230.10 284 393 3.8E-144 T 14-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain TSH58p_00680 09ba9a973036ab1fe2fbc493611adfc2 446 SUPERFAMILY SSF48256 26 445 1.96E-166 T 14-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 TSH58p_00680 09ba9a973036ab1fe2fbc493611adfc2 446 ProSitePatterns PS00480 Citrate synthase signature. 319 331 - T 14-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 TSH58p_12005 bd0e75062b60d1caf19f2eb28bf5f77e 191 Gene3D G3DSA:1.10.1740.10 15 96 6.2E-27 T 14-10-2018 TSH58p_12005 bd0e75062b60d1caf19f2eb28bf5f77e 191 Pfam PF04545 Sigma-70, region 4 136 185 2.5E-11 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 TSH58p_12005 bd0e75062b60d1caf19f2eb28bf5f77e 191 Gene3D G3DSA:1.10.10.10 97 188 3.0E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_12005 bd0e75062b60d1caf19f2eb28bf5f77e 191 SUPERFAMILY SSF88946 16 116 1.31E-23 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_12005 bd0e75062b60d1caf19f2eb28bf5f77e 191 SUPERFAMILY SSF88659 112 189 9.72E-14 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSH58p_12005 bd0e75062b60d1caf19f2eb28bf5f77e 191 Pfam PF04542 Sigma-70 region 2 34 102 1.4E-17 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_12005 bd0e75062b60d1caf19f2eb28bf5f77e 191 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 30 187 2.1E-26 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TSH58p_32595 184eb1d98794f511e879417ee7792e31 306 Pfam PF09130 Domain of unknown function (DUF1932) 205 275 1.1E-16 T 14-10-2018 IPR015814 Phosphogluconate dehydrogenase, NAD-binding, putative, C-terminal TSH58p_32595 184eb1d98794f511e879417ee7792e31 306 SUPERFAMILY SSF48179 177 282 3.74E-28 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_32595 184eb1d98794f511e879417ee7792e31 306 PIRSF PIRSF000103 4 302 3.6E-20 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 TSH58p_32595 184eb1d98794f511e879417ee7792e31 306 Gene3D G3DSA:3.40.50.720 10 183 8.0E-31 T 14-10-2018 TSH58p_32595 184eb1d98794f511e879417ee7792e31 306 Gene3D G3DSA:1.10.1040.10 185 304 5.1E-37 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSH58p_32595 184eb1d98794f511e879417ee7792e31 306 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 10 152 7.8E-8 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 TSH58p_32595 184eb1d98794f511e879417ee7792e31 306 SUPERFAMILY SSF51735 10 170 6.61E-29 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_10530 8ea01f9bcdb7c80d8029a69053065f37 187 Gene3D G3DSA:3.40.50.880 1 185 3.0E-39 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_10530 8ea01f9bcdb7c80d8029a69053065f37 187 SUPERFAMILY SSF52317 8 176 7.55E-31 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_10530 8ea01f9bcdb7c80d8029a69053065f37 187 Pfam PF01965 DJ-1/PfpI family 8 175 5.2E-34 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 TSH58p_00735 d780619d19cd28e3e84218a57f8ba5b3 513 Gene3D G3DSA:3.30.9.10 83 324 1.1E-134 T 14-10-2018 TSH58p_00735 d780619d19cd28e3e84218a57f8ba5b3 513 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 394 495 9.7E-15 T 14-10-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TSH58p_00735 d780619d19cd28e3e84218a57f8ba5b3 513 Pfam PF01266 FAD dependent oxidoreductase 6 362 4.2E-51 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TSH58p_00735 d780619d19cd28e3e84218a57f8ba5b3 513 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 10 27 - T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TSH58p_00735 d780619d19cd28e3e84218a57f8ba5b3 513 SUPERFAMILY SSF51905 5 301 1.45E-34 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_00735 d780619d19cd28e3e84218a57f8ba5b3 513 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 357 367 - T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TSH58p_00735 d780619d19cd28e3e84218a57f8ba5b3 513 Gene3D G3DSA:1.10.8.870 402 470 1.7E-23 T 14-10-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TSH58p_00735 d780619d19cd28e3e84218a57f8ba5b3 513 Gene3D G3DSA:3.50.50.60 6 371 1.1E-134 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_00735 d780619d19cd28e3e84218a57f8ba5b3 513 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 79 91 1.7E-27 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TSH58p_00735 d780619d19cd28e3e84218a57f8ba5b3 513 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 5 17 1.7E-27 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TSH58p_00735 d780619d19cd28e3e84218a57f8ba5b3 513 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 352 364 1.7E-27 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TSH58p_00735 d780619d19cd28e3e84218a57f8ba5b3 513 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 317 323 1.7E-27 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TSH58p_00735 d780619d19cd28e3e84218a57f8ba5b3 513 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 18 28 1.7E-27 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TSH58p_00735 d780619d19cd28e3e84218a57f8ba5b3 513 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 34 46 1.7E-27 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TSH58p_15410 b778624808e5fc3b6b5f379fa9f64328 240 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 14-10-2018 IPR019776 Flagellar basal body rod protein, conserved site TSH58p_15410 b778624808e5fc3b6b5f379fa9f64328 240 SUPERFAMILY SSF117143 77 197 2.22E-22 T 14-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like TSH58p_15410 b778624808e5fc3b6b5f379fa9f64328 240 TIGRFAM TIGR02490 flgF: flagellar basal-body rod protein FlgF 5 216 1.2E-60 T 14-10-2018 IPR012836 Flagellar basal-body rod FlgF GO:0030694|GO:0071973 TSH58p_15410 b778624808e5fc3b6b5f379fa9f64328 240 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 166 234 2.4E-18 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain TSH58p_15410 b778624808e5fc3b6b5f379fa9f64328 240 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 5 120 8.1E-40 T 14-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G TSH58p_15410 b778624808e5fc3b6b5f379fa9f64328 240 Pfam PF00460 Flagella basal body rod protein 5 35 1.0E-12 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 TSH58p_08690 eb0eb8a4c37de781f3433b6fd3711be3 1084 SUPERFAMILY SSF55785 528 635 5.06E-28 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_08690 eb0eb8a4c37de781f3433b6fd3711be3 1084 SMART SM00267 637 809 8.7E-65 T 14-10-2018 IPR000160 GGDEF domain TSH58p_08690 eb0eb8a4c37de781f3433b6fd3711be3 1084 Pfam PF00990 Diguanylate cyclase, GGDEF domain 648 804 3.0E-47 T 14-10-2018 IPR000160 GGDEF domain TSH58p_08690 eb0eb8a4c37de781f3433b6fd3711be3 1084 SUPERFAMILY SSF55785 425 523 2.27E-14 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_08690 eb0eb8a4c37de781f3433b6fd3711be3 1084 SUPERFAMILY SSF141868 824 1072 7.32E-88 T 14-10-2018 IPR035919 EAL domain superfamily TSH58p_08690 eb0eb8a4c37de781f3433b6fd3711be3 1084 Gene3D G3DSA:3.30.70.270 647 822 6.8E-60 T 14-10-2018 TSH58p_08690 eb0eb8a4c37de781f3433b6fd3711be3 1084 Pfam PF00563 EAL domain 825 1059 4.8E-70 T 14-10-2018 IPR001633 EAL domain TSH58p_08690 eb0eb8a4c37de781f3433b6fd3711be3 1084 SMART SM00052 819 1064 4.3E-110 T 14-10-2018 IPR001633 EAL domain TSH58p_08690 eb0eb8a4c37de781f3433b6fd3711be3 1084 SMART SM01049 86 180 4.5E-18 T 14-10-2018 IPR033480 Single Cache domain 2 TSH58p_08690 eb0eb8a4c37de781f3433b6fd3711be3 1084 SMART SM01049 221 293 2.0 T 14-10-2018 IPR033480 Single Cache domain 2 TSH58p_08690 eb0eb8a4c37de781f3433b6fd3711be3 1084 SMART SM00086 475 515 0.17 T 14-10-2018 IPR001610 PAC motif TSH58p_08690 eb0eb8a4c37de781f3433b6fd3711be3 1084 SMART SM00086 595 637 4.1E-5 T 14-10-2018 IPR001610 PAC motif TSH58p_08690 eb0eb8a4c37de781f3433b6fd3711be3 1084 SUPERFAMILY SSF55073 653 811 1.02E-48 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_08690 eb0eb8a4c37de781f3433b6fd3711be3 1084 Pfam PF13426 PAS domain 534 636 7.5E-17 T 14-10-2018 IPR000014 PAS domain TSH58p_08690 eb0eb8a4c37de781f3433b6fd3711be3 1084 Pfam PF13426 PAS domain 426 514 0.24 T 14-10-2018 IPR000014 PAS domain TSH58p_08690 eb0eb8a4c37de781f3433b6fd3711be3 1084 SMART SM00091 414 484 29.0 T 14-10-2018 IPR000014 PAS domain TSH58p_08690 eb0eb8a4c37de781f3433b6fd3711be3 1084 SMART SM00091 523 589 8.9E-7 T 14-10-2018 IPR000014 PAS domain TSH58p_08690 eb0eb8a4c37de781f3433b6fd3711be3 1084 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 645 806 5.0E-41 T 14-10-2018 IPR000160 GGDEF domain TSH58p_08690 eb0eb8a4c37de781f3433b6fd3711be3 1084 Gene3D G3DSA:3.30.450.20 525 646 3.8E-34 T 14-10-2018 TSH58p_08690 eb0eb8a4c37de781f3433b6fd3711be3 1084 Gene3D G3DSA:3.30.450.20 93 236 2.1E-32 T 14-10-2018 TSH58p_08690 eb0eb8a4c37de781f3433b6fd3711be3 1084 Pfam PF08269 Cache domain 51 345 1.4E-70 T 14-10-2018 IPR004010 Double Cache domain 2 TSH58p_08690 eb0eb8a4c37de781f3433b6fd3711be3 1084 Gene3D G3DSA:3.30.450.20 237 364 6.2E-22 T 14-10-2018 TSH58p_08690 eb0eb8a4c37de781f3433b6fd3711be3 1084 Gene3D G3DSA:3.20.20.450 823 1072 2.0E-95 T 14-10-2018 IPR035919 EAL domain superfamily TSH58p_08690 eb0eb8a4c37de781f3433b6fd3711be3 1084 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 462 522 4.4E-8 T 14-10-2018 IPR000014 PAS domain TSH58p_08690 eb0eb8a4c37de781f3433b6fd3711be3 1084 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 527 643 4.7E-21 T 14-10-2018 IPR000014 PAS domain TSH58p_08690 eb0eb8a4c37de781f3433b6fd3711be3 1084 Gene3D G3DSA:3.30.450.20 419 524 8.8E-13 T 14-10-2018 TSH58p_00840 0d49ab2d85352cea6d1fbf1b3319b159 323 Gene3D G3DSA:3.40.50.720 21 322 9.0E-76 T 14-10-2018 TSH58p_00840 0d49ab2d85352cea6d1fbf1b3319b159 323 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 224 9.0E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00840 0d49ab2d85352cea6d1fbf1b3319b159 323 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 32 49 9.0E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00840 0d49ab2d85352cea6d1fbf1b3319b159 323 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 102 113 9.0E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00840 0d49ab2d85352cea6d1fbf1b3319b159 323 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 163 9.0E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00840 0d49ab2d85352cea6d1fbf1b3319b159 323 SUPERFAMILY SSF51735 28 286 2.5E-51 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_00840 0d49ab2d85352cea6d1fbf1b3319b159 323 Pfam PF00106 short chain dehydrogenase 32 229 1.0E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_16715 d628b5dfebf1d4d411c8e8e51eca0486 161 PIRSF PIRSF002560 1 157 3.9E-69 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSH58p_16715 d628b5dfebf1d4d411c8e8e51eca0486 161 Gene3D G3DSA:1.20.1260.10 1 158 2.6E-67 T 14-10-2018 IPR012347 Ferritin-like TSH58p_16715 d628b5dfebf1d4d411c8e8e51eca0486 161 TIGRFAM TIGR00754 bfr: bacterioferritin 1 154 1.2E-72 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSH58p_16715 d628b5dfebf1d4d411c8e8e51eca0486 161 PRINTS PR00601 Bacterioferritin signature 128 149 5.0E-65 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSH58p_16715 d628b5dfebf1d4d411c8e8e51eca0486 161 PRINTS PR00601 Bacterioferritin signature 23 43 5.0E-65 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSH58p_16715 d628b5dfebf1d4d411c8e8e51eca0486 161 PRINTS PR00601 Bacterioferritin signature 3 22 5.0E-65 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSH58p_16715 d628b5dfebf1d4d411c8e8e51eca0486 161 PRINTS PR00601 Bacterioferritin signature 44 64 5.0E-65 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSH58p_16715 d628b5dfebf1d4d411c8e8e51eca0486 161 PRINTS PR00601 Bacterioferritin signature 86 106 5.0E-65 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSH58p_16715 d628b5dfebf1d4d411c8e8e51eca0486 161 PRINTS PR00601 Bacterioferritin signature 107 127 5.0E-65 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSH58p_16715 d628b5dfebf1d4d411c8e8e51eca0486 161 PRINTS PR00601 Bacterioferritin signature 65 85 5.0E-65 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSH58p_16715 d628b5dfebf1d4d411c8e8e51eca0486 161 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSH58p_16715 d628b5dfebf1d4d411c8e8e51eca0486 161 SUPERFAMILY SSF47240 1 154 6.37E-50 T 14-10-2018 IPR009078 Ferritin-like superfamily TSH58p_16715 d628b5dfebf1d4d411c8e8e51eca0486 161 Pfam PF00210 Ferritin-like domain 9 144 3.4E-38 T 14-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 TSH58p_00160 a4ce15e516853546293b417ec7e308bc 569 SMART SM00387 461 561 0.0013 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_00160 a4ce15e516853546293b417ec7e308bc 569 SUPERFAMILY SSF55874 428 559 6.02E-15 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_00160 a4ce15e516853546293b417ec7e308bc 569 Gene3D G3DSA:3.30.565.10 420 561 5.6E-14 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_00160 a4ce15e516853546293b417ec7e308bc 569 SMART SM00065 220 367 0.0071 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_00160 a4ce15e516853546293b417ec7e308bc 569 SUPERFAMILY SSF55781 245 365 2.94E-7 T 14-10-2018 TSH58p_00160 a4ce15e516853546293b417ec7e308bc 569 Pfam PF06580 Histidine kinase 373 449 4.3E-23 T 14-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 TSH58p_00160 a4ce15e516853546293b417ec7e308bc 569 Pfam PF07694 5TMR of 5TMR-LYT 30 198 1.0E-56 T 14-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 TSH58p_28325 00e0699bc78a0462ba6ec1faf6889b63 204 Gene3D G3DSA:3.40.50.150 41 176 4.5E-11 T 14-10-2018 TSH58p_28325 00e0699bc78a0462ba6ec1faf6889b63 204 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 61 91 - T 14-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 TSH58p_28325 00e0699bc78a0462ba6ec1faf6889b63 204 SUPERFAMILY SSF53335 27 169 5.78E-18 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_25390 73d95469d5497ace014633049470ed62 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.6E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_25390 73d95469d5497ace014633049470ed62 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.6E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_25390 73d95469d5497ace014633049470ed62 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.6E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_25390 73d95469d5497ace014633049470ed62 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.6E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_25390 73d95469d5497ace014633049470ed62 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.6E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_25390 73d95469d5497ace014633049470ed62 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.6E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_25390 73d95469d5497ace014633049470ed62 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 250 5.1E-59 T 14-10-2018 TSH58p_25390 73d95469d5497ace014633049470ed62 254 SUPERFAMILY SSF51735 4 252 2.82E-76 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_25390 73d95469d5497ace014633049470ed62 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 9.3E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_25390 73d95469d5497ace014633049470ed62 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 9.3E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_25390 73d95469d5497ace014633049470ed62 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 9.3E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_25390 73d95469d5497ace014633049470ed62 254 Gene3D G3DSA:3.40.50.720 1 254 7.3E-77 T 14-10-2018 TSH58p_25805 45a47e7757567475664c03b2df24cc08 448 SMART SM00387 339 446 6.8E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_25805 45a47e7757567475664c03b2df24cc08 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 389 2.7E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_25805 45a47e7757567475664c03b2df24cc08 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 424 2.7E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_25805 45a47e7757567475664c03b2df24cc08 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 443 2.7E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_25805 45a47e7757567475664c03b2df24cc08 448 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 341 444 5.4E-13 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_25805 45a47e7757567475664c03b2df24cc08 448 SUPERFAMILY SSF55874 312 444 9.3E-26 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_25805 45a47e7757567475664c03b2df24cc08 448 Gene3D G3DSA:3.30.565.10 303 446 3.2E-25 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_17265 ed52d059084f62bbb20f19abc697af1c 374 SUPERFAMILY SSF55821 3 209 2.52E-86 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily TSH58p_17265 ed52d059084f62bbb20f19abc697af1c 374 PIRSF PIRSF001259 8 374 7.9E-126 T 14-10-2018 TSH58p_17265 ed52d059084f62bbb20f19abc697af1c 374 Pfam PF00925 GTP cyclohydrolase II 217 365 5.1E-33 T 14-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TSH58p_17265 ed52d059084f62bbb20f19abc697af1c 374 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 13 205 1.2E-71 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TSH58p_17265 ed52d059084f62bbb20f19abc697af1c 374 Gene3D G3DSA:3.90.870.10 1 212 4.6E-87 T 14-10-2018 TSH58p_17265 ed52d059084f62bbb20f19abc697af1c 374 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 7 209 38.154 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TSH58p_17265 ed52d059084f62bbb20f19abc697af1c 374 SUPERFAMILY SSF142695 211 370 5.62E-42 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TSH58p_17265 ed52d059084f62bbb20f19abc697af1c 374 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 13 204 4.5E-83 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TSH58p_17265 ed52d059084f62bbb20f19abc697af1c 374 Gene3D G3DSA:3.40.50.10990 213 370 3.8E-30 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TSH58p_25105 a87843d04f38c5f74141fda274f4471f 600 Gene3D G3DSA:3.40.50.2000 383 597 4.0E-20 T 14-10-2018 TSH58p_25105 a87843d04f38c5f74141fda274f4471f 600 SMART SM00028 69 102 90.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25105 a87843d04f38c5f74141fda274f4471f 600 SMART SM00028 35 68 8.4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25105 a87843d04f38c5f74141fda274f4471f 600 SMART SM00028 171 204 4.6E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25105 a87843d04f38c5f74141fda274f4471f 600 SMART SM00028 103 136 0.15 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25105 a87843d04f38c5f74141fda274f4471f 600 SMART SM00028 137 170 10.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25105 a87843d04f38c5f74141fda274f4471f 600 Pfam PF13432 Tetratricopeptide repeat 151 203 9.6E-10 T 14-10-2018 TSH58p_25105 a87843d04f38c5f74141fda274f4471f 600 Pfam PF13432 Tetratricopeptide repeat 6 68 1.1E-6 T 14-10-2018 TSH58p_25105 a87843d04f38c5f74141fda274f4471f 600 Gene3D G3DSA:1.25.40.10 5 229 6.9E-45 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25105 a87843d04f38c5f74141fda274f4471f 600 SUPERFAMILY SSF48452 7 223 1.52E-33 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25105 a87843d04f38c5f74141fda274f4471f 600 SUPERFAMILY SSF53756 245 596 1.99E-20 T 14-10-2018 TSH58p_31745 f6f5ac9eaf8ae7fd6d821b17c03c0fec 215 SMART SM00421 151 208 2.0E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_31745 f6f5ac9eaf8ae7fd6d821b17c03c0fec 215 SUPERFAMILY SSF52172 2 135 1.85E-30 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_31745 f6f5ac9eaf8ae7fd6d821b17c03c0fec 215 Gene3D G3DSA:3.40.50.2300 2 146 6.1E-33 T 14-10-2018 TSH58p_31745 f6f5ac9eaf8ae7fd6d821b17c03c0fec 215 Gene3D G3DSA:1.10.10.10 147 215 8.2E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_31745 f6f5ac9eaf8ae7fd6d821b17c03c0fec 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 3.7E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_31745 f6f5ac9eaf8ae7fd6d821b17c03c0fec 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 3.7E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_31745 f6f5ac9eaf8ae7fd6d821b17c03c0fec 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 3.7E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_31745 f6f5ac9eaf8ae7fd6d821b17c03c0fec 215 SMART SM00448 3 121 2.9E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_31745 f6f5ac9eaf8ae7fd6d821b17c03c0fec 215 Pfam PF00072 Response regulator receiver domain 5 122 2.8E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_31745 f6f5ac9eaf8ae7fd6d821b17c03c0fec 215 SUPERFAMILY SSF46894 143 213 6.12E-18 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_31745 f6f5ac9eaf8ae7fd6d821b17c03c0fec 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 208 1.3E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_31750 5daa7f25c0b9b8737e04b18ada83a8d9 687 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 493 645 4.8E-28 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_31750 5daa7f25c0b9b8737e04b18ada83a8d9 687 Pfam PF00672 HAMP domain 340 387 8.3E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_31750 5daa7f25c0b9b8737e04b18ada83a8d9 687 Gene3D G3DSA:1.10.287.950 412 686 3.5E-53 T 14-10-2018 TSH58p_31750 5daa7f25c0b9b8737e04b18ada83a8d9 687 SUPERFAMILY SSF103190 142 220 8.89E-8 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily TSH58p_31750 5daa7f25c0b9b8737e04b18ada83a8d9 687 Gene3D G3DSA:1.10.8.500 339 390 8.2E-16 T 14-10-2018 TSH58p_31750 5daa7f25c0b9b8737e04b18ada83a8d9 687 Gene3D G3DSA:3.30.450.20 61 211 2.2E-39 T 14-10-2018 TSH58p_31750 5daa7f25c0b9b8737e04b18ada83a8d9 687 SMART SM00283 427 681 5.7E-43 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_31750 5daa7f25c0b9b8737e04b18ada83a8d9 687 Pfam PF02743 Cache domain 45 299 1.7E-21 T 14-10-2018 IPR033479 Double Cache domain 1 TSH58p_31750 5daa7f25c0b9b8737e04b18ada83a8d9 687 Gene3D G3DSA:3.30.450.20 52 309 2.2E-39 T 14-10-2018 TSH58p_31750 5daa7f25c0b9b8737e04b18ada83a8d9 687 SMART SM00304 338 391 1.8E-6 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_31750 5daa7f25c0b9b8737e04b18ada83a8d9 687 SUPERFAMILY SSF58104 366 680 5.1E-61 T 14-10-2018 TSH58p_01235 ca49dc99ecf8c5b423faf5d047f6f51b 365 Pfam PF01968 Hydantoinase/oxoprolinase 61 308 4.3E-12 T 14-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 TSH58p_01235 ca49dc99ecf8c5b423faf5d047f6f51b 365 Gene3D G3DSA:3.30.420.40 5 119 1.5E-17 T 14-10-2018 TSH58p_01235 ca49dc99ecf8c5b423faf5d047f6f51b 365 Gene3D G3DSA:3.30.420.190 121 350 5.6E-59 T 14-10-2018 TSH58p_01235 ca49dc99ecf8c5b423faf5d047f6f51b 365 TIGRFAM TIGR03123 one_C_unchar_1: probable H4MPT-linked C1 transfer pathway protein 7 320 3.3E-94 T 14-10-2018 IPR002756 4-[[4-(2-aminoethyl)phenoxy]-methyl]-2-furanmethanamine-glutamate synthase KEGG: 00680+2.5.1.131|MetaCyc: PWY-5254 TSH58p_01235 ca49dc99ecf8c5b423faf5d047f6f51b 365 SUPERFAMILY SSF53067 7 164 7.5E-9 T 14-10-2018 TSH58p_23115 9662adde40b806b77f4d88b4e26f358f 446 Gene3D G3DSA:3.40.50.2300 2 137 9.8E-31 T 14-10-2018 TSH58p_23115 9662adde40b806b77f4d88b4e26f358f 446 SUPERFAMILY SSF52172 2 183 3.27E-39 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_23115 9662adde40b806b77f4d88b4e26f358f 446 Pfam PF00072 Response regulator receiver domain 5 110 2.7E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_23115 9662adde40b806b77f4d88b4e26f358f 446 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 405 422 8.1E-7 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_23115 9662adde40b806b77f4d88b4e26f358f 446 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 422 442 8.1E-7 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_23115 9662adde40b806b77f4d88b4e26f358f 446 SMART SM00448 2 113 4.4E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_23115 9662adde40b806b77f4d88b4e26f358f 446 Pfam PF00158 Sigma-54 interaction domain 139 303 1.6E-63 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 TSH58p_23115 9662adde40b806b77f4d88b4e26f358f 446 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 225 240 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 TSH58p_23115 9662adde40b806b77f4d88b4e26f358f 446 Gene3D G3DSA:1.10.10.60 387 443 6.8E-11 T 14-10-2018 TSH58p_23115 9662adde40b806b77f4d88b4e26f358f 446 SUPERFAMILY SSF52540 139 377 1.09E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_23115 9662adde40b806b77f4d88b4e26f358f 446 SMART SM00382 159 302 8.5E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_23115 9662adde40b806b77f4d88b4e26f358f 446 Gene3D G3DSA:1.10.8.60 310 384 6.1E-16 T 14-10-2018 TSH58p_23115 9662adde40b806b77f4d88b4e26f358f 446 Gene3D G3DSA:3.40.50.300 138 309 9.6E-60 T 14-10-2018 TSH58p_23115 9662adde40b806b77f4d88b4e26f358f 446 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 348 357 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site TSH58p_23115 9662adde40b806b77f4d88b4e26f358f 446 SUPERFAMILY SSF46689 348 441 3.76E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_23115 9662adde40b806b77f4d88b4e26f358f 446 Pfam PF02954 Bacterial regulatory protein, Fis family 399 432 9.6E-9 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_14680 b850213774f5f2cb66f0252e6940917c 223 Pfam PF01810 LysE type translocator 19 217 4.2E-37 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 TSH58p_14680 b850213774f5f2cb66f0252e6940917c 223 PIRSF PIRSF006324 5 220 7.3E-55 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 TSH58p_00340 3399dcce1c5db74aa074b40945cb7648 273 Gene3D G3DSA:2.150.10.10 1 56 2.9E-11 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_00340 3399dcce1c5db74aa074b40945cb7648 273 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 20 38 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_00340 3399dcce1c5db74aa074b40945cb7648 273 PRINTS PR00313 NodO calcium binding signature 87 95 1.8E-11 T 14-10-2018 TSH58p_00340 3399dcce1c5db74aa074b40945cb7648 273 PRINTS PR00313 NodO calcium binding signature 96 104 1.8E-11 T 14-10-2018 TSH58p_00340 3399dcce1c5db74aa074b40945cb7648 273 PRINTS PR00313 NodO calcium binding signature 141 150 1.8E-11 T 14-10-2018 TSH58p_00340 3399dcce1c5db74aa074b40945cb7648 273 PRINTS PR00313 NodO calcium binding signature 66 77 1.8E-11 T 14-10-2018 TSH58p_00340 3399dcce1c5db74aa074b40945cb7648 273 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 6 22 0.15 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_00340 3399dcce1c5db74aa074b40945cb7648 273 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 177 193 0.0015 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_00340 3399dcce1c5db74aa074b40945cb7648 273 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 60 76 0.0024 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_00340 3399dcce1c5db74aa074b40945cb7648 273 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 87 103 0.0039 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_00340 3399dcce1c5db74aa074b40945cb7648 273 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 113 130 0.019 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_00340 3399dcce1c5db74aa074b40945cb7648 273 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 159 175 0.0032 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_00340 3399dcce1c5db74aa074b40945cb7648 273 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 42 58 0.07 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_00340 3399dcce1c5db74aa074b40945cb7648 273 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 24 40 0.04 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_00340 3399dcce1c5db74aa074b40945cb7648 273 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 141 157 0.006 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_00340 3399dcce1c5db74aa074b40945cb7648 273 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 173 191 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_00340 3399dcce1c5db74aa074b40945cb7648 273 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 29 47 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_00340 3399dcce1c5db74aa074b40945cb7648 273 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 164 182 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_00340 3399dcce1c5db74aa074b40945cb7648 273 SUPERFAMILY SSF51120 4 119 1.01E-23 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_00340 3399dcce1c5db74aa074b40945cb7648 273 Gene3D G3DSA:2.150.10.10 153 269 7.3E-27 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_00340 3399dcce1c5db74aa074b40945cb7648 273 Gene3D G3DSA:2.150.10.10 111 152 6.5E-12 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_00340 3399dcce1c5db74aa074b40945cb7648 273 Gene3D G3DSA:2.150.10.10 57 110 2.6E-14 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_00340 3399dcce1c5db74aa074b40945cb7648 273 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 155 173 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_00340 3399dcce1c5db74aa074b40945cb7648 273 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 38 56 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_00340 3399dcce1c5db74aa074b40945cb7648 273 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 56 74 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_00340 3399dcce1c5db74aa074b40945cb7648 273 SUPERFAMILY SSF51120 93 265 4.11E-34 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_00340 3399dcce1c5db74aa074b40945cb7648 273 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 146 164 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_00340 3399dcce1c5db74aa074b40945cb7648 273 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 47 65 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_20295 1dbe9d8bbf8ca09033e546bd6320a853 352 SUPERFAMILY SSF51735 148 351 2.85E-54 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_20295 1dbe9d8bbf8ca09033e546bd6320a853 352 PIRSF PIRSF000188 2 352 1.7E-145 T 14-10-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 TSH58p_20295 1dbe9d8bbf8ca09033e546bd6320a853 352 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 223 306 5.9E-9 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSH58p_20295 1dbe9d8bbf8ca09033e546bd6320a853 352 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 181 201 2.2E-17 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSH58p_20295 1dbe9d8bbf8ca09033e546bd6320a853 352 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 66 80 2.2E-17 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSH58p_20295 1dbe9d8bbf8ca09033e546bd6320a853 352 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 291 302 2.2E-17 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSH58p_20295 1dbe9d8bbf8ca09033e546bd6320a853 352 Gene3D G3DSA:3.40.50.720 134 341 7.9E-142 T 14-10-2018 TSH58p_20295 1dbe9d8bbf8ca09033e546bd6320a853 352 SMART SM00839 149 352 1.3E-78 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSH58p_20295 1dbe9d8bbf8ca09033e546bd6320a853 352 SUPERFAMILY SSF53223 4 136 1.82E-43 T 14-10-2018 TSH58p_20295 1dbe9d8bbf8ca09033e546bd6320a853 352 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 74 87 - T 14-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSH58p_20295 1dbe9d8bbf8ca09033e546bd6320a853 352 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 14 131 3.0E-25 T 14-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSH58p_20295 1dbe9d8bbf8ca09033e546bd6320a853 352 Gene3D G3DSA:3.40.50.10860 11 348 7.9E-142 T 14-10-2018 TSH58p_16010 ab11d0e119e55d2fde6d0f612f43910e 174 Gene3D G3DSA:3.30.70.260 92 172 1.0E-10 T 14-10-2018 TSH58p_16010 ab11d0e119e55d2fde6d0f612f43910e 174 SUPERFAMILY SSF55021 93 171 1.45E-10 T 14-10-2018 TSH58p_16010 ab11d0e119e55d2fde6d0f612f43910e 174 Pfam PF13740 ACT domain 97 169 2.3E-5 T 14-10-2018 TSH58p_16010 ab11d0e119e55d2fde6d0f612f43910e 174 SUPERFAMILY SSF55021 4 82 1.49E-11 T 14-10-2018 TSH58p_16010 ab11d0e119e55d2fde6d0f612f43910e 174 Gene3D G3DSA:3.30.70.260 3 82 7.0E-11 T 14-10-2018 TSH58p_01760 818349aa7a8368213a7338ec1f4e86b2 367 Gene3D G3DSA:3.40.50.300 22 241 2.5E-64 T 14-10-2018 TSH58p_01760 818349aa7a8368213a7338ec1f4e86b2 367 Gene3D G3DSA:2.40.50.940 242 300 4.1E-10 T 14-10-2018 TSH58p_01760 818349aa7a8368213a7338ec1f4e86b2 367 Pfam PF00005 ABC transporter 40 180 1.1E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_01760 818349aa7a8368213a7338ec1f4e86b2 367 SUPERFAMILY SSF50331 257 362 2.35E-14 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSH58p_01760 818349aa7a8368213a7338ec1f4e86b2 367 Gene3D G3DSA:2.40.50.140 301 357 4.1E-10 T 14-10-2018 TSH58p_01760 818349aa7a8368213a7338ec1f4e86b2 367 Pfam PF08402 TOBE domain 294 365 5.6E-16 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TSH58p_01760 818349aa7a8368213a7338ec1f4e86b2 367 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_01760 818349aa7a8368213a7338ec1f4e86b2 367 SUPERFAMILY SSF52540 23 262 2.27E-84 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_01760 818349aa7a8368213a7338ec1f4e86b2 367 SMART SM00382 47 230 2.9E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_21090 fb5878fe5fc9b89212325feb08777d9d 373 SUPERFAMILY SSF53850 47 373 1.7E-52 T 14-10-2018 TSH58p_21090 fb5878fe5fc9b89212325feb08777d9d 373 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 119 132 2.5E-5 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSH58p_21090 fb5878fe5fc9b89212325feb08777d9d 373 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 278 297 2.5E-5 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSH58p_21090 fb5878fe5fc9b89212325feb08777d9d 373 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 174 188 2.5E-5 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSH58p_21090 fb5878fe5fc9b89212325feb08777d9d 373 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 72 93 2.5E-5 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSH58p_21090 fb5878fe5fc9b89212325feb08777d9d 373 Pfam PF13416 Bacterial extracellular solute-binding protein 69 332 3.4E-31 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSH58p_21090 fb5878fe5fc9b89212325feb08777d9d 373 Gene3D G3DSA:3.40.190.10 159 284 3.3E-57 T 14-10-2018 TSH58p_21090 fb5878fe5fc9b89212325feb08777d9d 373 Gene3D G3DSA:3.40.190.10 63 342 3.3E-57 T 14-10-2018 TSH58p_00830 45560f1acadf8d19e2911fb196ac2e22 703 SUPERFAMILY SSF52172 30 183 6.12E-37 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_00830 45560f1acadf8d19e2911fb196ac2e22 703 Pfam PF00072 Response regulator receiver domain 574 685 1.8E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_00830 45560f1acadf8d19e2911fb196ac2e22 703 Pfam PF00072 Response regulator receiver domain 33 145 2.5E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_00830 45560f1acadf8d19e2911fb196ac2e22 703 PRINTS PR00344 Bacterial sensor protein C-terminal signature 496 506 2.3E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_00830 45560f1acadf8d19e2911fb196ac2e22 703 PRINTS PR00344 Bacterial sensor protein C-terminal signature 478 492 2.3E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_00830 45560f1acadf8d19e2911fb196ac2e22 703 PRINTS PR00344 Bacterial sensor protein C-terminal signature 533 546 2.3E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_00830 45560f1acadf8d19e2911fb196ac2e22 703 PRINTS PR00344 Bacterial sensor protein C-terminal signature 509 527 2.3E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_00830 45560f1acadf8d19e2911fb196ac2e22 703 SMART SM00086 266 308 2.6E-4 T 14-10-2018 IPR001610 PAC motif TSH58p_00830 45560f1acadf8d19e2911fb196ac2e22 703 SUPERFAMILY SSF55874 380 549 2.88E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_00830 45560f1acadf8d19e2911fb196ac2e22 703 Gene3D G3DSA:3.40.50.2300 29 178 2.0E-34 T 14-10-2018 TSH58p_00830 45560f1acadf8d19e2911fb196ac2e22 703 Pfam PF00512 His Kinase A (phospho-acceptor) domain 325 387 4.4E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_00830 45560f1acadf8d19e2911fb196ac2e22 703 SMART SM00448 31 145 5.1E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_00830 45560f1acadf8d19e2911fb196ac2e22 703 SMART SM00448 572 685 5.7E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_00830 45560f1acadf8d19e2911fb196ac2e22 703 Pfam PF08447 PAS fold 217 302 2.6E-16 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 TSH58p_00830 45560f1acadf8d19e2911fb196ac2e22 703 Gene3D G3DSA:1.10.287.130 315 388 1.0E-17 T 14-10-2018 TSH58p_00830 45560f1acadf8d19e2911fb196ac2e22 703 Gene3D G3DSA:3.30.450.20 181 306 1.2E-24 T 14-10-2018 TSH58p_00830 45560f1acadf8d19e2911fb196ac2e22 703 SUPERFAMILY SSF52172 574 690 7.97E-26 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_00830 45560f1acadf8d19e2911fb196ac2e22 703 SMART SM00388 323 389 2.2E-7 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_00830 45560f1acadf8d19e2911fb196ac2e22 703 Gene3D G3DSA:3.40.50.2300 570 693 3.1E-25 T 14-10-2018 TSH58p_00830 45560f1acadf8d19e2911fb196ac2e22 703 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 432 546 1.6E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_00830 45560f1acadf8d19e2911fb196ac2e22 703 SUPERFAMILY SSF47384 316 386 5.3E-10 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_00830 45560f1acadf8d19e2911fb196ac2e22 703 SMART SM00387 430 549 1.2E-28 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_00830 45560f1acadf8d19e2911fb196ac2e22 703 Gene3D G3DSA:3.30.565.10 390 557 3.7E-44 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_00830 45560f1acadf8d19e2911fb196ac2e22 703 SUPERFAMILY SSF55785 178 306 1.36E-17 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_05150 a44506a42a123d2cdf8b48f14ea76b7c 291 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 237 250 - T 14-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site TSH58p_05150 a44506a42a123d2cdf8b48f14ea76b7c 291 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 14-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site TSH58p_05150 a44506a42a123d2cdf8b48f14ea76b7c 291 Pfam PF02629 CoA binding domain 6 99 4.6E-32 T 14-10-2018 IPR003781 CoA-binding GO:0048037 TSH58p_05150 a44506a42a123d2cdf8b48f14ea76b7c 291 Gene3D G3DSA:3.40.50.261 124 290 3.2E-70 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSH58p_05150 a44506a42a123d2cdf8b48f14ea76b7c 291 Gene3D G3DSA:3.40.50.720 2 123 2.4E-53 T 14-10-2018 TSH58p_05150 a44506a42a123d2cdf8b48f14ea76b7c 291 SUPERFAMILY SSF51735 1 122 5.78E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_05150 a44506a42a123d2cdf8b48f14ea76b7c 291 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 289 42.562 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSH58p_05150 a44506a42a123d2cdf8b48f14ea76b7c 291 PIRSF PIRSF001553 1 291 2.5E-131 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSH58p_05150 a44506a42a123d2cdf8b48f14ea76b7c 291 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 3.4E-37 T 14-10-2018 TSH58p_05150 a44506a42a123d2cdf8b48f14ea76b7c 291 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 3.4E-37 T 14-10-2018 TSH58p_05150 a44506a42a123d2cdf8b48f14ea76b7c 291 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 3.4E-37 T 14-10-2018 TSH58p_05150 a44506a42a123d2cdf8b48f14ea76b7c 291 PRINTS PR01798 Succinyl-CoA synthase signature 241 258 3.4E-37 T 14-10-2018 TSH58p_05150 a44506a42a123d2cdf8b48f14ea76b7c 291 SUPERFAMILY SSF52210 123 288 1.83E-51 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSH58p_05150 a44506a42a123d2cdf8b48f14ea76b7c 291 SMART SM00881 4 100 1.2E-37 T 14-10-2018 IPR003781 CoA-binding GO:0048037 TSH58p_05150 a44506a42a123d2cdf8b48f14ea76b7c 291 Pfam PF00549 CoA-ligase 151 265 6.9E-18 T 14-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSH58p_05150 a44506a42a123d2cdf8b48f14ea76b7c 291 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 288 1.2E-138 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSH58p_27350 13c6fcf4d7a3c8f64ff1a0a6dba5e552 316 SUPERFAMILY SSF50129 1 150 7.0E-40 T 14-10-2018 IPR011032 GroES-like superfamily TSH58p_27350 13c6fcf4d7a3c8f64ff1a0a6dba5e552 316 Pfam PF13602 Zinc-binding dehydrogenase 187 312 1.1E-24 T 14-10-2018 TSH58p_27350 13c6fcf4d7a3c8f64ff1a0a6dba5e552 316 Gene3D G3DSA:3.90.180.10 8 311 1.9E-96 T 14-10-2018 TSH58p_27350 13c6fcf4d7a3c8f64ff1a0a6dba5e552 316 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 92 2.7E-10 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TSH58p_27350 13c6fcf4d7a3c8f64ff1a0a6dba5e552 316 Gene3D G3DSA:3.40.50.720 128 263 1.9E-96 T 14-10-2018 TSH58p_27350 13c6fcf4d7a3c8f64ff1a0a6dba5e552 316 SUPERFAMILY SSF51735 117 282 4.63E-40 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_27350 13c6fcf4d7a3c8f64ff1a0a6dba5e552 316 SMART SM00829 10 312 3.2E-29 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TSH58p_27350 13c6fcf4d7a3c8f64ff1a0a6dba5e552 316 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 145 166 - T 14-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 TSH58p_25940 a890184ce859e5b1b6baaf79a1534043 284 SUPERFAMILY SSF53335 5 280 2.52E-54 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_25940 a890184ce859e5b1b6baaf79a1534043 284 Gene3D G3DSA:1.10.8.10 3 87 2.1E-23 T 14-10-2018 TSH58p_25940 a890184ce859e5b1b6baaf79a1534043 284 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 27 278 6.9E-81 T 14-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 TSH58p_25940 a890184ce859e5b1b6baaf79a1534043 284 Pfam PF13847 Methyltransferase domain 117 192 7.2E-12 T 14-10-2018 IPR025714 Methyltransferase domain TSH58p_25940 a890184ce859e5b1b6baaf79a1534043 284 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 5 282 44.342 T 14-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 TSH58p_25940 a890184ce859e5b1b6baaf79a1534043 284 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 8 283 3.7E-60 T 14-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 TSH58p_25940 a890184ce859e5b1b6baaf79a1534043 284 Gene3D G3DSA:3.40.50.150 88 284 3.6E-59 T 14-10-2018 TSH58p_25940 a890184ce859e5b1b6baaf79a1534043 284 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 186 192 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TSH58p_07125 0134de8a5acf0a6b63856313bc819297 445 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 28 444 1.6E-111 T 14-10-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 TSH58p_07125 0134de8a5acf0a6b63856313bc819297 445 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 424 444 2.2E-51 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_07125 0134de8a5acf0a6b63856313bc819297 445 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 342 366 2.2E-51 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_07125 0134de8a5acf0a6b63856313bc819297 445 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 36 59 2.2E-51 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_07125 0134de8a5acf0a6b63856313bc819297 445 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 366 389 2.2E-51 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_07125 0134de8a5acf0a6b63856313bc819297 445 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 78 98 2.2E-51 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_07125 0134de8a5acf0a6b63856313bc819297 445 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 309 330 2.2E-51 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_07125 0134de8a5acf0a6b63856313bc819297 445 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 409 424 2.2E-51 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_07125 0134de8a5acf0a6b63856313bc819297 445 Gene3D G3DSA:2.40.50.100 297 333 3.3E-17 T 14-10-2018 TSH58p_07125 0134de8a5acf0a6b63856313bc819297 445 Gene3D G3DSA:1.10.287.470 224 296 3.3E-17 T 14-10-2018 TSH58p_07125 0134de8a5acf0a6b63856313bc819297 445 Pfam PF13437 HlyD family secretion protein 297 395 1.4E-12 T 14-10-2018 TSH58p_07125 0134de8a5acf0a6b63856313bc819297 445 Gene3D G3DSA:2.40.50.100 73 136 1.2E-6 T 14-10-2018 TSH58p_07125 0134de8a5acf0a6b63856313bc819297 445 Gene3D G3DSA:2.40.30.170 334 421 3.3E-17 T 14-10-2018 TSH58p_07125 0134de8a5acf0a6b63856313bc819297 445 SUPERFAMILY SSF111369 238 327 3.79E-5 T 14-10-2018 TSH58p_07125 0134de8a5acf0a6b63856313bc819297 445 Pfam PF13533 Biotin-lipoyl like 76 107 9.3E-6 T 14-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain TSH58p_29910 af330e6ddf9004a52faca34e7a6b303b 402 Gene3D G3DSA:3.30.1330.50 243 401 2.7E-66 T 14-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TSH58p_29910 af330e6ddf9004a52faca34e7a6b303b 402 Gene3D G3DSA:3.90.550.10 6 242 1.5E-74 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_29910 af330e6ddf9004a52faca34e7a6b303b 402 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 16 236 3.5E-69 T 14-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 TSH58p_29910 af330e6ddf9004a52faca34e7a6b303b 402 SUPERFAMILY SSF69765 245 399 2.49E-63 T 14-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TSH58p_29910 af330e6ddf9004a52faca34e7a6b303b 402 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 245 400 33.541 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TSH58p_29910 af330e6ddf9004a52faca34e7a6b303b 402 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 279 294 - T 14-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TSH58p_29910 af330e6ddf9004a52faca34e7a6b303b 402 SUPERFAMILY SSF53448 14 238 1.64E-59 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_29910 af330e6ddf9004a52faca34e7a6b303b 402 Hamap MF_01520 Bifunctional enzyme IspD/IspF [ispDF]. 12 401 44.346 T 14-10-2018 IPR026596 Bifunctional enzyme IspD/IspF KEGG: 00900+4.6.1.12+2.7.7.60|MetaCyc: PWY-7560 TSH58p_29910 af330e6ddf9004a52faca34e7a6b303b 402 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 13 238 42.086 T 14-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 TSH58p_29910 af330e6ddf9004a52faca34e7a6b303b 402 Pfam PF02542 YgbB family 245 398 2.1E-61 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TSH58p_29910 af330e6ddf9004a52faca34e7a6b303b 402 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 246 398 5.9E-63 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TSH58p_29910 af330e6ddf9004a52faca34e7a6b303b 402 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 15 236 4.9E-67 T 14-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 TSH58p_29910 af330e6ddf9004a52faca34e7a6b303b 402 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 110 117 - T 14-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 TSH58p_27260 64b562cff0aee4df14b4c0b3c7d0bb69 266 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 223 238 7.4E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TSH58p_27260 64b562cff0aee4df14b4c0b3c7d0bb69 266 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 238 254 7.4E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TSH58p_27260 64b562cff0aee4df14b4c0b3c7d0bb69 266 Pfam PF02311 AraC-like ligand binding domain 22 143 7.6E-8 T 14-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 TSH58p_27260 64b562cff0aee4df14b4c0b3c7d0bb69 266 Gene3D G3DSA:1.10.10.60 219 260 4.3E-8 T 14-10-2018 TSH58p_27260 64b562cff0aee4df14b4c0b3c7d0bb69 266 SMART SM00342 172 254 1.5E-19 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TSH58p_27260 64b562cff0aee4df14b4c0b3c7d0bb69 266 Gene3D G3DSA:1.10.10.60 155 217 1.2E-7 T 14-10-2018 TSH58p_27260 64b562cff0aee4df14b4c0b3c7d0bb69 266 SUPERFAMILY SSF46689 213 255 2.78E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_27260 64b562cff0aee4df14b4c0b3c7d0bb69 266 SUPERFAMILY SSF51182 23 180 4.89E-12 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_27260 64b562cff0aee4df14b4c0b3c7d0bb69 266 Pfam PF12833 Helix-turn-helix domain 179 255 7.3E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TSH58p_27260 64b562cff0aee4df14b4c0b3c7d0bb69 266 SUPERFAMILY SSF46689 168 207 2.27E-5 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_24840 6936ddfef9eb7a46eca4ca4f14df2370 419 SUPERFAMILY SSF51445 52 414 1.96E-53 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_24840 6936ddfef9eb7a46eca4ca4f14df2370 419 Gene3D G3DSA:3.20.20.80 53 413 1.4E-54 T 14-10-2018 TSH58p_24840 6936ddfef9eb7a46eca4ca4f14df2370 419 PRINTS PR00134 Glycosyl hydrolase family 10 signature 194 205 6.0E-6 T 14-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSH58p_24840 6936ddfef9eb7a46eca4ca4f14df2370 419 PRINTS PR00134 Glycosyl hydrolase family 10 signature 253 264 6.0E-6 T 14-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSH58p_24840 6936ddfef9eb7a46eca4ca4f14df2370 419 PRINTS PR00134 Glycosyl hydrolase family 10 signature 286 298 6.0E-6 T 14-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSH58p_24840 6936ddfef9eb7a46eca4ca4f14df2370 419 SMART SM00633 99 412 7.5E-6 T 14-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSH58p_24840 6936ddfef9eb7a46eca4ca4f14df2370 419 Pfam PF00331 Glycosyl hydrolase family 10 56 410 1.1E-40 T 14-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSH58p_08395 fa1801c9e1d10f51fc56fe2ccc2f244f 390 Gene3D G3DSA:3.30.420.40 2 190 4.2E-57 T 14-10-2018 TSH58p_08395 fa1801c9e1d10f51fc56fe2ccc2f244f 390 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 5 16 - T 14-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_08395 fa1801c9e1d10f51fc56fe2ccc2f244f 390 Pfam PF00871 Acetokinase family 5 377 6.6E-98 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_08395 fa1801c9e1d10f51fc56fe2ccc2f244f 390 SUPERFAMILY SSF53067 154 385 1.3E-75 T 14-10-2018 TSH58p_08395 fa1801c9e1d10f51fc56fe2ccc2f244f 390 PIRSF PIRSF000722 1 388 9.4E-129 T 14-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_08395 fa1801c9e1d10f51fc56fe2ccc2f244f 390 PRINTS PR00471 Acetate kinase family signature 5 16 2.5E-38 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_08395 fa1801c9e1d10f51fc56fe2ccc2f244f 390 PRINTS PR00471 Acetate kinase family signature 291 304 2.5E-38 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_08395 fa1801c9e1d10f51fc56fe2ccc2f244f 390 PRINTS PR00471 Acetate kinase family signature 169 182 2.5E-38 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_08395 fa1801c9e1d10f51fc56fe2ccc2f244f 390 PRINTS PR00471 Acetate kinase family signature 365 377 2.5E-38 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_08395 fa1801c9e1d10f51fc56fe2ccc2f244f 390 PRINTS PR00471 Acetate kinase family signature 313 329 2.5E-38 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_08395 fa1801c9e1d10f51fc56fe2ccc2f244f 390 PRINTS PR00471 Acetate kinase family signature 198 219 2.5E-38 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_08395 fa1801c9e1d10f51fc56fe2ccc2f244f 390 SUPERFAMILY SSF53067 4 190 3.32E-56 T 14-10-2018 TSH58p_08395 fa1801c9e1d10f51fc56fe2ccc2f244f 390 TIGRFAM TIGR00016 ackA: acetate kinase 3 380 4.4E-97 T 14-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_08395 fa1801c9e1d10f51fc56fe2ccc2f244f 390 Hamap MF_00020 Acetate kinase [ackA]. 1 387 152.846 T 14-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_08395 fa1801c9e1d10f51fc56fe2ccc2f244f 390 Gene3D G3DSA:3.30.420.40 194 389 2.0E-70 T 14-10-2018 TSH58p_08395 fa1801c9e1d10f51fc56fe2ccc2f244f 390 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 198 215 - T 14-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_16710 03ca32cba9b5a84fa42234ce73a70c14 729 SUPERFAMILY SSF51445 170 727 4.8E-142 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_16710 03ca32cba9b5a84fa42234ce73a70c14 729 Pfam PF02446 4-alpha-glucanotransferase 189 704 1.1E-118 T 14-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 TSH58p_16710 03ca32cba9b5a84fa42234ce73a70c14 729 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 137 722 3.8E-136 T 14-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 TSH58p_16710 03ca32cba9b5a84fa42234ce73a70c14 729 Gene3D G3DSA:3.20.20.80 182 724 4.4E-126 T 14-10-2018 TSH58p_08685 4f1c53efd5d96beb05a241089f52ac0b 141 Gene3D G3DSA:1.10.3680.10 7 136 8.2E-15 T 14-10-2018 IPR029024 TerB-like TSH58p_08685 4f1c53efd5d96beb05a241089f52ac0b 141 SUPERFAMILY SSF158682 2 124 1.83E-19 T 14-10-2018 IPR029024 TerB-like TSH58p_08685 4f1c53efd5d96beb05a241089f52ac0b 141 Pfam PF05099 Tellurite resistance protein TerB 17 122 2.5E-9 T 14-10-2018 IPR007791 Co-chaperone DjlA, N-terminal TSH58p_26335 65a6f6e1bc3d7c601607f789b4ad2bfc 447 Gene3D G3DSA:3.10.450.350 168 411 1.9E-85 T 14-10-2018 TSH58p_26335 65a6f6e1bc3d7c601607f789b4ad2bfc 447 Gene3D G3DSA:2.70.70.10 266 396 1.9E-85 T 14-10-2018 IPR011055 Duplicated hybrid motif TSH58p_26335 65a6f6e1bc3d7c601607f789b4ad2bfc 447 SUPERFAMILY SSF51261 147 391 3.87E-66 T 14-10-2018 IPR011055 Duplicated hybrid motif TSH58p_26335 65a6f6e1bc3d7c601607f789b4ad2bfc 447 Pfam PF01551 Peptidase family M23 294 390 1.2E-31 T 14-10-2018 IPR016047 Peptidase M23 TSH58p_00645 7f12accc395532b0f138855c23b1d7e6 361 Gene3D G3DSA:3.40.50.180 169 359 4.2E-56 T 14-10-2018 IPR035909 Methylesterase CheB, C-terminal TSH58p_00645 7f12accc395532b0f138855c23b1d7e6 361 PIRSF PIRSF000876 1 361 1.4E-110 T 14-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 TSH58p_00645 7f12accc395532b0f138855c23b1d7e6 361 Pfam PF01339 CheB methylesterase 175 354 8.0E-50 T 14-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 TSH58p_00645 7f12accc395532b0f138855c23b1d7e6 361 Gene3D G3DSA:3.40.50.2300 1 131 3.8E-29 T 14-10-2018 TSH58p_00645 7f12accc395532b0f138855c23b1d7e6 361 Pfam PF00072 Response regulator receiver domain 4 110 9.5E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_00645 7f12accc395532b0f138855c23b1d7e6 361 SMART SM00448 2 114 1.9E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_00645 7f12accc395532b0f138855c23b1d7e6 361 SUPERFAMILY SSF52172 1 125 1.71E-28 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_00645 7f12accc395532b0f138855c23b1d7e6 361 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 2 360 34.429 T 14-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 TSH58p_00645 7f12accc395532b0f138855c23b1d7e6 361 SUPERFAMILY SSF52738 172 360 4.84E-54 T 14-10-2018 IPR035909 Methylesterase CheB, C-terminal TSH58p_05380 e18ec2b5a65f1c77252e8b09fea3b249 561 Gene3D G3DSA:1.10.8.500 214 259 3.3E-8 T 14-10-2018 TSH58p_05380 e18ec2b5a65f1c77252e8b09fea3b249 561 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 428 457 4.9E-11 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_05380 e18ec2b5a65f1c77252e8b09fea3b249 561 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 476 505 4.9E-11 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_05380 e18ec2b5a65f1c77252e8b09fea3b249 561 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 329 358 4.9E-11 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_05380 e18ec2b5a65f1c77252e8b09fea3b249 561 SMART SM00283 301 555 3.7E-44 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_05380 e18ec2b5a65f1c77252e8b09fea3b249 561 Gene3D G3DSA:3.30.450.20 33 189 1.5E-39 T 14-10-2018 TSH58p_05380 e18ec2b5a65f1c77252e8b09fea3b249 561 Pfam PF17200 Single Cache domain 2 39 188 6.8E-33 T 14-10-2018 IPR033480 Single Cache domain 2 TSH58p_05380 e18ec2b5a65f1c77252e8b09fea3b249 561 SMART SM01049 34 127 4.4E-25 T 14-10-2018 IPR033480 Single Cache domain 2 TSH58p_05380 e18ec2b5a65f1c77252e8b09fea3b249 561 Gene3D G3DSA:1.10.287.950 260 555 3.4E-50 T 14-10-2018 TSH58p_05380 e18ec2b5a65f1c77252e8b09fea3b249 561 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 364 523 2.8E-28 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_05380 e18ec2b5a65f1c77252e8b09fea3b249 561 SUPERFAMILY SSF58104 239 554 1.96E-58 T 14-10-2018 TSH58p_14725 860d259a5c7c9929b1471086f7781df5 150 Gene3D G3DSA:3.10.450.160 54 150 1.7E-21 T 14-10-2018 TSH58p_31925 d715f6e1a1add9f46897390741d7f359 269 Gene3D G3DSA:1.10.12.10 212 269 6.3E-14 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal TSH58p_31925 d715f6e1a1add9f46897390741d7f359 269 SUPERFAMILY SSF52096 13 268 1.13E-68 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_31925 d715f6e1a1add9f46897390741d7f359 269 Gene3D G3DSA:3.90.226.10 7 211 5.2E-59 T 14-10-2018 TSH58p_31925 d715f6e1a1add9f46897390741d7f359 269 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 110 130 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 TSH58p_31925 d715f6e1a1add9f46897390741d7f359 269 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 268 4.7E-45 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TSH58p_17240 77fa5dd63f2e7b092d5dcdd388c8a62e 143 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 4 142 1.6E-48 T 14-10-2018 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 TSH58p_17240 77fa5dd63f2e7b092d5dcdd388c8a62e 143 Pfam PF02502 Ribose/Galactose Isomerase 4 142 2.3E-56 T 14-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 TSH58p_17240 77fa5dd63f2e7b092d5dcdd388c8a62e 143 SUPERFAMILY SSF89623 2 142 1.96E-56 T 14-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 TSH58p_17240 77fa5dd63f2e7b092d5dcdd388c8a62e 143 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 4 142 1.8E-53 T 14-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 TSH58p_17240 77fa5dd63f2e7b092d5dcdd388c8a62e 143 PIRSF PIRSF005384 2 143 7.5E-58 T 14-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 TSH58p_17240 77fa5dd63f2e7b092d5dcdd388c8a62e 143 Gene3D G3DSA:3.40.1400.10 1 143 1.2E-58 T 14-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 TSH58p_10785 abc55072ebf29bb58e76eff4e69ed1f6 225 SUPERFAMILY SSF46689 21 93 7.7E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_10785 abc55072ebf29bb58e76eff4e69ed1f6 225 Gene3D G3DSA:1.10.357.10 93 219 1.0E-30 T 14-10-2018 TSH58p_10785 abc55072ebf29bb58e76eff4e69ed1f6 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 35 79 4.2E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_10785 abc55072ebf29bb58e76eff4e69ed1f6 225 Gene3D G3DSA:1.10.10.60 20 87 4.9E-29 T 14-10-2018 TSH58p_10785 abc55072ebf29bb58e76eff4e69ed1f6 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 55 78 3.8E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_10785 abc55072ebf29bb58e76eff4e69ed1f6 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 47 3.8E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_10785 abc55072ebf29bb58e76eff4e69ed1f6 225 SUPERFAMILY SSF48498 100 215 1.84E-24 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TSH58p_10785 abc55072ebf29bb58e76eff4e69ed1f6 225 ProSitePatterns PS01081 TetR-type HTH domain signature. 46 76 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site TSH58p_24595 4fabfed8e2a216c442cdc0e1903b40f1 400 SUPERFAMILY SSF47203 252 397 3.22E-40 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TSH58p_24595 4fabfed8e2a216c442cdc0e1903b40f1 400 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 145 157 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TSH58p_24595 4fabfed8e2a216c442cdc0e1903b40f1 400 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 352 371 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TSH58p_24595 4fabfed8e2a216c442cdc0e1903b40f1 400 Gene3D G3DSA:2.40.110.10 142 246 5.4E-39 T 14-10-2018 TSH58p_24595 4fabfed8e2a216c442cdc0e1903b40f1 400 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 143 234 4.2E-21 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TSH58p_24595 4fabfed8e2a216c442cdc0e1903b40f1 400 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 28 139 3.2E-31 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TSH58p_24595 4fabfed8e2a216c442cdc0e1903b40f1 400 Gene3D G3DSA:1.20.140.10 249 400 5.4E-39 T 14-10-2018 TSH58p_24595 4fabfed8e2a216c442cdc0e1903b40f1 400 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 253 393 3.0E-26 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TSH58p_24595 4fabfed8e2a216c442cdc0e1903b40f1 400 SUPERFAMILY SSF56645 15 245 5.24E-77 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TSH58p_24595 4fabfed8e2a216c442cdc0e1903b40f1 400 Gene3D G3DSA:1.10.540.10 14 140 2.1E-39 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TSH58p_07665 0dde5b596b0a3b6ab0a5fa6f0f043568 471 Gene3D G3DSA:3.40.50.12380 178 450 5.9E-99 T 14-10-2018 TSH58p_07665 0dde5b596b0a3b6ab0a5fa6f0f043568 471 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 43 442 1.7E-105 T 14-10-2018 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 TSH58p_07665 0dde5b596b0a3b6ab0a5fa6f0f043568 471 ProSitePatterns PS00699 Nitrogenases component 1 alpha and beta subunits signature 1. 61 68 - T 14-10-2018 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 TSH58p_07665 0dde5b596b0a3b6ab0a5fa6f0f043568 471 SUPERFAMILY SSF53807 18 457 3.6E-138 T 14-10-2018 TSH58p_07665 0dde5b596b0a3b6ab0a5fa6f0f043568 471 Gene3D G3DSA:3.40.50.1980 29 177 2.7E-50 T 14-10-2018 TSH58p_07665 0dde5b596b0a3b6ab0a5fa6f0f043568 471 ProSitePatterns PS00090 Nitrogenases component 1 alpha and beta subunits signature 2. 127 141 - T 14-10-2018 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 TSH58p_07665 0dde5b596b0a3b6ab0a5fa6f0f043568 471 TIGRFAM TIGR01283 nifE: nitrogenase MoFe cofactor biosynthesis protein NifE 3 456 1.5E-192 T 14-10-2018 IPR005973 Nitrogenase MoFe cofactor biosynthesis protein NifE GO:0009399|GO:0065003 TSH58p_11340 603e753a5567422c1485535e26f9075b 462 SMART SM00729 152 372 1.3E-55 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSH58p_11340 603e753a5567422c1485535e26f9075b 462 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 4 443 3.3E-146 T 14-10-2018 TSH58p_11340 603e753a5567422c1485535e26f9075b 462 Pfam PF00919 Uncharacterized protein family UPF0004 4 108 3.4E-29 T 14-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 TSH58p_11340 603e753a5567422c1485535e26f9075b 462 SUPERFAMILY SSF102114 128 376 4.05E-58 T 14-10-2018 TSH58p_11340 603e753a5567422c1485535e26f9075b 462 Gene3D G3DSA:3.80.30.20 151 386 8.3E-79 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TSH58p_11340 603e753a5567422c1485535e26f9075b 462 Pfam PF01938 TRAM domain 383 443 9.5E-8 T 14-10-2018 IPR002792 TRAM domain TSH58p_11340 603e753a5567422c1485535e26f9075b 462 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 3 444 71.666 T 14-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 TSH58p_11340 603e753a5567422c1485535e26f9075b 462 Gene3D G3DSA:3.40.50.12160 3 140 6.6E-33 T 14-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily TSH58p_11340 603e753a5567422c1485535e26f9075b 462 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 4 441 3.0E-142 T 14-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 TSH58p_11340 603e753a5567422c1485535e26f9075b 462 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 156 176 - T 14-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 TSH58p_11340 603e753a5567422c1485535e26f9075b 462 Pfam PF04055 Radical SAM superfamily 158 330 1.4E-27 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSH58p_11450 7257e22a57bec2e417be1b6ba8e7188d 249 Gene3D G3DSA:3.20.20.190 1 245 1.5E-81 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TSH58p_11450 7257e22a57bec2e417be1b6ba8e7188d 249 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 11 237 6.9E-44 T 14-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 TSH58p_11450 7257e22a57bec2e417be1b6ba8e7188d 249 SUPERFAMILY SSF51695 6 240 5.76E-70 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TSH58p_05010 5ea915dde3431e4c655ba820b5cc2b48 421 Gene3D G3DSA:3.40.50.2000 2 399 5.1E-125 T 14-10-2018 TSH58p_05010 5ea915dde3431e4c655ba820b5cc2b48 421 SUPERFAMILY SSF53756 1 413 5.89E-99 T 14-10-2018 TSH58p_05010 5ea915dde3431e4c655ba820b5cc2b48 421 Gene3D G3DSA:3.40.50.2000 231 397 5.1E-125 T 14-10-2018 TSH58p_05010 5ea915dde3431e4c655ba820b5cc2b48 421 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 255 378 7.7E-5 T 14-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 TSH58p_05010 5ea915dde3431e4c655ba820b5cc2b48 421 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 4 143 2.9E-10 T 14-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_25100 57c72fb1fcaf46bc94769666a6a39c3b 516 SMART SM00028 86 119 220.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25100 57c72fb1fcaf46bc94769666a6a39c3b 516 SMART SM00028 120 153 0.52 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25100 57c72fb1fcaf46bc94769666a6a39c3b 516 SMART SM00028 154 187 0.24 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25100 57c72fb1fcaf46bc94769666a6a39c3b 516 SMART SM00028 52 85 0.67 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25100 57c72fb1fcaf46bc94769666a6a39c3b 516 Gene3D G3DSA:1.25.40.10 21 122 2.4E-17 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25100 57c72fb1fcaf46bc94769666a6a39c3b 516 SUPERFAMILY SSF53756 240 481 7.53E-24 T 14-10-2018 TSH58p_25100 57c72fb1fcaf46bc94769666a6a39c3b 516 Pfam PF13432 Tetratricopeptide repeat 165 211 1.4E-5 T 14-10-2018 TSH58p_25100 57c72fb1fcaf46bc94769666a6a39c3b 516 Pfam PF13432 Tetratricopeptide repeat 25 85 4.0E-7 T 14-10-2018 TSH58p_25100 57c72fb1fcaf46bc94769666a6a39c3b 516 Pfam PF13432 Tetratricopeptide repeat 91 147 0.0014 T 14-10-2018 TSH58p_25100 57c72fb1fcaf46bc94769666a6a39c3b 516 SUPERFAMILY SSF48452 22 212 4.55E-30 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25100 57c72fb1fcaf46bc94769666a6a39c3b 516 Gene3D G3DSA:1.25.40.10 159 229 2.1E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25100 57c72fb1fcaf46bc94769666a6a39c3b 516 Gene3D G3DSA:1.25.40.10 123 158 1.6E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 Pfam PF13193 AMP-binding enzyme C-terminal domain 1942 2024 9.1E-10 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 Pfam PF13193 AMP-binding enzyme C-terminal domain 887 961 4.7E-12 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 Gene3D G3DSA:3.30.300.30 873 970 3.1E-29 T 14-10-2018 TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 Gene3D G3DSA:3.30.559.10 1083 1448 5.9E-102 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1671 1682 - T 14-10-2018 IPR020845 AMP-binding, conserved site TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 Pfam PF00501 AMP-binding enzyme 468 879 3.2E-88 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 Pfam PF00501 AMP-binding enzyme 1535 1934 5.8E-102 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 SUPERFAMILY SSF52777 195 430 1.78E-38 T 14-10-2018 TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 Gene3D G3DSA:3.40.50.12780 1522 1926 4.2E-141 T 14-10-2018 TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 ProSitePatterns PS00455 Putative AMP-binding domain signature. 616 627 - T 14-10-2018 IPR020845 AMP-binding, conserved site TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 Gene3D G3DSA:1.10.1200.10 971 1051 1.9E-19 T 14-10-2018 IPR036736 ACP-like superfamily TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 Pfam PF00668 Condensation domain 3 429 8.8E-56 T 14-10-2018 IPR001242 Condensation domain TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 Pfam PF00668 Condensation domain 1079 1513 2.4E-60 T 14-10-2018 IPR001242 Condensation domain TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 Gene3D G3DSA:3.30.559.10 7 209 2.2E-46 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 SUPERFAMILY SSF52777 9 186 5.56E-26 T 14-10-2018 TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 Gene3D G3DSA:3.30.559.30 1264 1510 5.9E-102 T 14-10-2018 TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 SUPERFAMILY SSF53474 2130 2375 1.18E-43 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 Gene3D G3DSA:3.40.50.12780 453 872 1.9E-120 T 14-10-2018 TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 Gene3D G3DSA:3.40.50.1820 2040 2378 1.1E-101 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 Gene3D G3DSA:3.30.559.30 214 438 5.3E-53 T 14-10-2018 TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 SUPERFAMILY SSF47336 978 1048 9.42E-13 T 14-10-2018 IPR036736 ACP-like superfamily TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1553 1958 2.8E-130 T 14-10-2018 IPR010071 Amino acid adenylation domain TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 490 903 5.7E-112 T 14-10-2018 IPR010071 Amino acid adenylation domain TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 Pfam PF00975 Thioesterase domain 2148 2363 3.1E-26 T 14-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 SMART SM00824 Thioesterase 2150 2373 4.6E-4 T 14-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 SUPERFAMILY SSF52777 1265 1497 5.56E-44 T 14-10-2018 TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 SMART SM00823 Phosphopantetheine attachment site 2050 2120 6.8E-4 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 SMART SM00823 Phosphopantetheine attachment site 984 1052 0.0049 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 SUPERFAMILY SSF52777 1074 1278 1.11E-34 T 14-10-2018 TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 Pfam PF00550 Phosphopantetheine attachment site 987 1045 9.8E-10 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 Pfam PF00550 Phosphopantetheine attachment site 2054 2115 6.2E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1008 1023 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2075 2090 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 SUPERFAMILY SSF56801 430 996 9.68E-135 T 14-10-2018 TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 SUPERFAMILY SSF47336 2045 2117 1.07E-15 T 14-10-2018 IPR036736 ACP-like superfamily TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 Gene3D G3DSA:3.30.300.30 1928 2039 1.0E-32 T 14-10-2018 TSH58p_23470 9a02f3d1474a5b8e654b18e794fcae76 2394 SUPERFAMILY SSF56801 1493 2063 1.57E-156 T 14-10-2018 TSH58p_24330 c42255affd345b3a8c039f3dfe6ead93 123 SMART SM00448 1 116 3.3E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_24330 c42255affd345b3a8c039f3dfe6ead93 123 Pfam PF00072 Response regulator receiver domain 3 117 2.1E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_24330 c42255affd345b3a8c039f3dfe6ead93 123 SUPERFAMILY SSF52172 1 119 4.41E-31 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_24330 c42255affd345b3a8c039f3dfe6ead93 123 Gene3D G3DSA:3.40.50.2300 1 123 1.4E-30 T 14-10-2018 TSH58p_23640 e8095e5b8673d8300550f5378c1a7b26 346 SMART SM00387 248 345 8.6E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_23640 e8095e5b8673d8300550f5378c1a7b26 346 Gene3D G3DSA:3.40.50.2300 5 158 1.7E-30 T 14-10-2018 TSH58p_23640 e8095e5b8673d8300550f5378c1a7b26 346 SUPERFAMILY SSF55874 231 343 3.54E-19 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_23640 e8095e5b8673d8300550f5378c1a7b26 346 SMART SM00448 6 120 8.2E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_23640 e8095e5b8673d8300550f5378c1a7b26 346 PRINTS PR00344 Bacterial sensor protein C-terminal signature 329 342 1.8E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_23640 e8095e5b8673d8300550f5378c1a7b26 346 PRINTS PR00344 Bacterial sensor protein C-terminal signature 288 302 1.8E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_23640 e8095e5b8673d8300550f5378c1a7b26 346 PRINTS PR00344 Bacterial sensor protein C-terminal signature 306 324 1.8E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_23640 e8095e5b8673d8300550f5378c1a7b26 346 Pfam PF00072 Response regulator receiver domain 8 109 2.6E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_23640 e8095e5b8673d8300550f5378c1a7b26 346 Gene3D G3DSA:3.30.565.10 210 345 1.5E-28 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_23640 e8095e5b8673d8300550f5378c1a7b26 346 Pfam PF07568 Histidine kinase 153 224 2.4E-19 T 14-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain TSH58p_23640 e8095e5b8673d8300550f5378c1a7b26 346 Pfam PF13581 Histidine kinase-like ATPase domain 236 340 1.9E-12 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_23640 e8095e5b8673d8300550f5378c1a7b26 346 SUPERFAMILY SSF52172 6 155 2.99E-29 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_06170 025044e1794b926bea2258cf41cde106 229 Gene3D G3DSA:1.20.120.530 86 228 1.3E-32 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_06170 025044e1794b926bea2258cf41cde106 229 SMART SM00345 25 83 3.5E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_06170 025044e1794b926bea2258cf41cde106 229 SMART SM00895 93 214 1.7E-18 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_06170 025044e1794b926bea2258cf41cde106 229 Pfam PF07729 FCD domain 94 212 1.1E-25 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_06170 025044e1794b926bea2258cf41cde106 229 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 83 9.7E-20 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_06170 025044e1794b926bea2258cf41cde106 229 SUPERFAMILY SSF46785 17 106 6.45E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_06170 025044e1794b926bea2258cf41cde106 229 Gene3D G3DSA:1.10.10.10 3 84 2.5E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_06170 025044e1794b926bea2258cf41cde106 229 SUPERFAMILY SSF48008 92 222 3.14E-26 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_19570 de16900f06e878922af3df33ce8b156e 534 Gene3D G3DSA:3.30.450.20 190 306 9.0E-17 T 14-10-2018 TSH58p_19570 de16900f06e878922af3df33ce8b156e 534 Gene3D G3DSA:3.30.450.40 34 189 5.3E-29 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_19570 de16900f06e878922af3df33ce8b156e 534 SUPERFAMILY SSF55785 177 306 1.27E-18 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_19570 de16900f06e878922af3df33ce8b156e 534 SUPERFAMILY SSF55874 411 533 5.76E-20 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_19570 de16900f06e878922af3df33ce8b156e 534 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 187 316 5.1E-14 T 14-10-2018 IPR000014 PAS domain TSH58p_19570 de16900f06e878922af3df33ce8b156e 534 SMART SM00086 267 309 6.3E-4 T 14-10-2018 IPR001610 PAC motif TSH58p_19570 de16900f06e878922af3df33ce8b156e 534 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 438 533 9.0E-11 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_19570 de16900f06e878922af3df33ce8b156e 534 Pfam PF13185 GAF domain 35 177 1.0E-14 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_19570 de16900f06e878922af3df33ce8b156e 534 SMART SM00387 430 534 1.8E-14 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_19570 de16900f06e878922af3df33ce8b156e 534 Gene3D G3DSA:3.30.565.10 391 534 3.9E-26 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_19570 de16900f06e878922af3df33ce8b156e 534 SUPERFAMILY SSF55781 36 188 1.01E-24 T 14-10-2018 TSH58p_19570 de16900f06e878922af3df33ce8b156e 534 Pfam PF08448 PAS fold 196 310 2.0E-9 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_19570 de16900f06e878922af3df33ce8b156e 534 Pfam PF07568 Histidine kinase 332 406 1.1E-15 T 14-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain TSH58p_19570 de16900f06e878922af3df33ce8b156e 534 SMART SM00065 18 186 3.9E-7 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_19570 de16900f06e878922af3df33ce8b156e 534 PRINTS PR00344 Bacterial sensor protein C-terminal signature 520 533 1.6E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_19570 de16900f06e878922af3df33ce8b156e 534 PRINTS PR00344 Bacterial sensor protein C-terminal signature 493 511 1.6E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_19570 de16900f06e878922af3df33ce8b156e 534 PRINTS PR00344 Bacterial sensor protein C-terminal signature 470 484 1.6E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_23020 7afda25f84d305fc23b56b8151e16293 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_23020 7afda25f84d305fc23b56b8151e16293 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 7.3E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_23020 7afda25f84d305fc23b56b8151e16293 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 7.3E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_23020 7afda25f84d305fc23b56b8151e16293 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 7.3E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_23020 7afda25f84d305fc23b56b8151e16293 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 7.3E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_23020 7afda25f84d305fc23b56b8151e16293 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 7.3E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_23020 7afda25f84d305fc23b56b8151e16293 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 6.4E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_23020 7afda25f84d305fc23b56b8151e16293 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 6.4E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_23020 7afda25f84d305fc23b56b8151e16293 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 6.4E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_23020 7afda25f84d305fc23b56b8151e16293 252 SUPERFAMILY SSF51735 1 210 1.04E-51 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_23020 7afda25f84d305fc23b56b8151e16293 252 Pfam PF00106 short chain dehydrogenase 6 191 4.2E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_23020 7afda25f84d305fc23b56b8151e16293 252 Gene3D G3DSA:3.40.50.720 1 242 2.2E-52 T 14-10-2018 TSH58p_15140 71e866f556d1ad395b7cb842a48cd628 123 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15140 71e866f556d1ad395b7cb842a48cd628 123 Gene3D G3DSA:2.40.50.140 1 123 4.2E-65 T 14-10-2018 TSH58p_15140 71e866f556d1ad395b7cb842a48cd628 123 PRINTS PR01034 Ribosomal protein S12 signature 27 42 1.9E-62 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15140 71e866f556d1ad395b7cb842a48cd628 123 PRINTS PR01034 Ribosomal protein S12 signature 58 77 1.9E-62 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15140 71e866f556d1ad395b7cb842a48cd628 123 PRINTS PR01034 Ribosomal protein S12 signature 42 57 1.9E-62 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15140 71e866f556d1ad395b7cb842a48cd628 123 PRINTS PR01034 Ribosomal protein S12 signature 77 94 1.9E-62 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15140 71e866f556d1ad395b7cb842a48cd628 123 PRINTS PR01034 Ribosomal protein S12 signature 94 110 1.9E-62 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15140 71e866f556d1ad395b7cb842a48cd628 123 PRINTS PR01034 Ribosomal protein S12 signature 110 122 1.9E-62 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15140 71e866f556d1ad395b7cb842a48cd628 123 SUPERFAMILY SSF50249 2 123 7.54E-54 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_15140 71e866f556d1ad395b7cb842a48cd628 123 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.821 T 14-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_15140 71e866f556d1ad395b7cb842a48cd628 123 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 123 1.6E-69 T 14-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_15140 71e866f556d1ad395b7cb842a48cd628 123 Pfam PF00164 Ribosomal protein S12/S23 13 123 4.4E-44 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15140 71e866f556d1ad395b7cb842a48cd628 123 PIRSF PIRSF002133 1 123 3.0E-55 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_24700 d3393912781424d9420b99f18b17b49c 359 Pfam PF13614 AAA domain 18 191 8.8E-43 T 14-10-2018 IPR025669 AAA domain TSH58p_24700 d3393912781424d9420b99f18b17b49c 359 Gene3D G3DSA:3.40.50.300 10 265 1.3E-60 T 14-10-2018 TSH58p_24700 d3393912781424d9420b99f18b17b49c 359 SUPERFAMILY SSF52540 16 263 4.62E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_03775 40afd5e6bb5c244d45c36ef7aad9e6fb 165 Pfam PF06073 Bacterial protein of unknown function (DUF934) 51 156 1.3E-36 T 14-10-2018 IPR008318 Uncharacterised conserved protein UCP030820 TSH58p_03775 40afd5e6bb5c244d45c36ef7aad9e6fb 165 PIRSF PIRSF030820 2 164 8.7E-45 T 14-10-2018 IPR008318 Uncharacterised conserved protein UCP030820 TSH58p_24030 342b65951512f0708ab6c61232d2c840 357 TIGRFAM TIGR02475 CobW: cobalamin biosynthesis protein CobW 10 356 2.5E-155 T 14-10-2018 IPR012824 Cobalamin (vitamin B12) biosynthesis CobW GO:0009236 TSH58p_24030 342b65951512f0708ab6c61232d2c840 357 SUPERFAMILY SSF90002 267 356 5.1E-19 T 14-10-2018 TSH58p_24030 342b65951512f0708ab6c61232d2c840 357 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 267 356 3.0E-18 T 14-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal TSH58p_24030 342b65951512f0708ab6c61232d2c840 357 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 12 207 5.3E-56 T 14-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain TSH58p_24030 342b65951512f0708ab6c61232d2c840 357 SMART SM00833 267 356 1.5E-10 T 14-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal TSH58p_24030 342b65951512f0708ab6c61232d2c840 357 Gene3D G3DSA:3.30.1220.10 245 357 1.2E-19 T 14-10-2018 IPR036627 CobW-like, C-terminal domain superfamily TSH58p_24030 342b65951512f0708ab6c61232d2c840 357 SUPERFAMILY SSF52540 11 207 2.6E-30 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_24030 342b65951512f0708ab6c61232d2c840 357 Gene3D G3DSA:3.40.50.300 8 243 2.7E-56 T 14-10-2018 TSH58p_29590 200ee52a0aa29cc46d8835b74e0ad1e8 302 Pfam PF01556 DnaJ C terminal domain 133 275 7.9E-33 T 14-10-2018 IPR002939 Chaperone DnaJ, C-terminal TSH58p_29590 200ee52a0aa29cc46d8835b74e0ad1e8 302 PRINTS PR00625 DnaJ domain signature 23 38 3.9E-21 T 14-10-2018 IPR001623 DnaJ domain TSH58p_29590 200ee52a0aa29cc46d8835b74e0ad1e8 302 PRINTS PR00625 DnaJ domain signature 5 23 3.9E-21 T 14-10-2018 IPR001623 DnaJ domain TSH58p_29590 200ee52a0aa29cc46d8835b74e0ad1e8 302 PRINTS PR00625 DnaJ domain signature 40 60 3.9E-21 T 14-10-2018 IPR001623 DnaJ domain TSH58p_29590 200ee52a0aa29cc46d8835b74e0ad1e8 302 SUPERFAMILY SSF46565 2 118 3.14E-28 T 14-10-2018 IPR036869 Chaperone J-domain superfamily TSH58p_29590 200ee52a0aa29cc46d8835b74e0ad1e8 302 SMART SM00271 2 60 1.7E-29 T 14-10-2018 IPR001623 DnaJ domain TSH58p_29590 200ee52a0aa29cc46d8835b74e0ad1e8 302 SUPERFAMILY SSF49493 125 203 4.97E-19 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TSH58p_29590 200ee52a0aa29cc46d8835b74e0ad1e8 302 SUPERFAMILY SSF49493 201 277 7.33E-22 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TSH58p_29590 200ee52a0aa29cc46d8835b74e0ad1e8 302 Gene3D G3DSA:2.60.260.20 127 195 1.3E-16 T 14-10-2018 TSH58p_29590 200ee52a0aa29cc46d8835b74e0ad1e8 302 Gene3D G3DSA:2.60.260.20 197 275 1.5E-29 T 14-10-2018 TSH58p_29590 200ee52a0aa29cc46d8835b74e0ad1e8 302 Gene3D G3DSA:1.10.287.110 1 125 1.3E-30 T 14-10-2018 IPR036869 Chaperone J-domain superfamily TSH58p_29590 200ee52a0aa29cc46d8835b74e0ad1e8 302 ProSitePatterns PS00636 Nt-dnaJ domain signature. 45 64 - T 14-10-2018 IPR018253 DnaJ domain, conserved site TSH58p_29590 200ee52a0aa29cc46d8835b74e0ad1e8 302 Pfam PF00226 DnaJ domain 3 65 5.5E-26 T 14-10-2018 IPR001623 DnaJ domain TSH58p_32410 6a1e6f042b6f848f1655749faa909167 84 SUPERFAMILY SSF143011 1 81 7.72E-19 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily TSH58p_32410 6a1e6f042b6f848f1655749faa909167 84 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 4 80 1.8E-11 T 14-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family TSH58p_32410 6a1e6f042b6f848f1655749faa909167 84 Gene3D G3DSA:3.30.2310.20 3 84 5.3E-17 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily TSH58p_23035 04fe630f6e33dab785985bc014724073 335 SUPERFAMILY SSF52540 11 259 5.1E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_23035 04fe630f6e33dab785985bc014724073 335 Pfam PF00005 ABC transporter 31 188 1.8E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_23035 04fe630f6e33dab785985bc014724073 335 Gene3D G3DSA:3.40.50.300 8 334 2.9E-98 T 14-10-2018 TSH58p_23035 04fe630f6e33dab785985bc014724073 335 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 240 327 1.3E-19 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_23035 04fe630f6e33dab785985bc014724073 335 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 240 309 7.4E-18 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_23035 04fe630f6e33dab785985bc014724073 335 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_23035 04fe630f6e33dab785985bc014724073 335 SMART SM00382 39 238 1.6E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_29175 b826c15ad376c32c816fb2e7f182e5c0 241 Gene3D G3DSA:3.90.550.10 11 238 4.0E-46 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_29175 b826c15ad376c32c816fb2e7f182e5c0 241 Pfam PF00483 Nucleotidyl transferase 14 197 9.5E-22 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TSH58p_29175 b826c15ad376c32c816fb2e7f182e5c0 241 SUPERFAMILY SSF53448 14 234 1.45E-46 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 Gene3D G3DSA:3.30.450.20 738 858 2.2E-10 T 14-10-2018 TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 Pfam PF03705 CheR methyltransferase, all-alpha domain 236 288 1.0E-10 T 14-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 SMART SM00448 1418 1531 1.8E-16 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 Pfam PF00072 Response regulator receiver domain 1420 1531 2.7E-13 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 Gene3D G3DSA:3.30.565.10 1247 1397 3.6E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 SUPERFAMILY SSF55785 738 858 3.26E-6 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 SMART SM00091 751 816 15.0 T 14-10-2018 IPR000014 PAS domain TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 SMART SM00091 533 598 210.0 T 14-10-2018 IPR000014 PAS domain TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 SMART SM00091 1045 1111 0.055 T 14-10-2018 IPR000014 PAS domain TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 SUPERFAMILY SSF47757 232 303 1.96E-11 T 14-10-2018 TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 SMART SM00138 235 496 5.8E-80 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 SUPERFAMILY SSF55874 1234 1397 4.71E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 SMART SM00387 1288 1399 1.7E-27 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 SUPERFAMILY SSF55781 892 1043 4.14E-19 T 14-10-2018 TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 Pfam PF00512 His Kinase A (phospho-acceptor) domain 1180 1244 4.4E-7 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 Pfam PF08448 PAS fold 1052 1160 9.4E-8 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 SUPERFAMILY SSF55785 1032 1157 3.21E-10 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 Gene3D G3DSA:3.40.50.150 300 498 2.2E-60 T 14-10-2018 TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 SUPERFAMILY SSF52172 1417 1536 5.98E-24 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 Gene3D G3DSA:3.30.450.40 867 1043 5.9E-21 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 Pfam PF13185 GAF domain 891 1032 8.0E-14 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 Gene3D G3DSA:3.30.450.20 1044 1155 3.3E-7 T 14-10-2018 TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1289 1398 6.1E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 SUPERFAMILY SSF47384 1164 1244 1.1E-9 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 Gene3D G3DSA:3.40.50.2300 1415 1542 9.8E-22 T 14-10-2018 TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 Pfam PF13596 PAS domain 753 858 7.7E-25 T 14-10-2018 TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 SMART SM00388 1179 1244 2.8E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 Pfam PF01739 CheR methyltransferase, SAM binding domain 302 491 3.9E-52 T 14-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 Gene3D G3DSA:1.10.287.130 1156 1242 5.6E-12 T 14-10-2018 TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 PRINTS PR00996 Glutamate methyltransferase family signature 334 354 1.7E-22 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 PRINTS PR00996 Glutamate methyltransferase family signature 436 450 1.7E-22 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 PRINTS PR00996 Glutamate methyltransferase family signature 370 386 1.7E-22 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 PRINTS PR00996 Glutamate methyltransferase family signature 294 306 1.7E-22 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 PRINTS PR00996 Glutamate methyltransferase family signature 455 478 1.7E-22 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 SMART SM00065 889 1041 6.7E-8 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 Gene3D G3DSA:3.40.50.180 26 216 1.3E-62 T 14-10-2018 IPR035909 Methylesterase CheB, C-terminal TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 SUPERFAMILY SSF52738 29 214 6.67E-53 T 14-10-2018 IPR035909 Methylesterase CheB, C-terminal TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 Pfam PF01339 CheB methylesterase 33 207 2.0E-55 T 14-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 TSH58p_18015 93caeeee5c84038b0b2020e8a2fcbbc5 1546 SUPERFAMILY SSF53335 302 495 1.12E-47 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_26230 138fa50d649627b77703f2bf9115e272 290 Gene3D G3DSA:3.40.50.1980 29 158 1.1E-18 T 14-10-2018 TSH58p_26230 138fa50d649627b77703f2bf9115e272 290 SUPERFAMILY SSF53807 37 284 1.41E-34 T 14-10-2018 TSH58p_26230 138fa50d649627b77703f2bf9115e272 290 Gene3D G3DSA:3.40.50.1980 167 286 8.6E-13 T 14-10-2018 TSH58p_26230 138fa50d649627b77703f2bf9115e272 290 Pfam PF01497 Periplasmic binding protein 41 234 3.7E-16 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain TSH58p_15350 b373dae9c00687edd6ffeec30a94b55a 151 Pfam PF01575 MaoC like domain 17 114 7.1E-16 T 14-10-2018 IPR002539 MaoC-like dehydratase domain TSH58p_15350 b373dae9c00687edd6ffeec30a94b55a 151 SUPERFAMILY SSF54637 2 149 1.07E-39 T 14-10-2018 IPR029069 HotDog domain superfamily TSH58p_15350 b373dae9c00687edd6ffeec30a94b55a 151 Gene3D G3DSA:3.10.129.10 1 151 9.2E-47 T 14-10-2018 TSH58p_14100 fc0c5be5d04afe412bac4278aa385f38 341 Gene3D G3DSA:3.20.20.70 9 341 3.5E-84 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_14100 fc0c5be5d04afe412bac4278aa385f38 341 Pfam PF04055 Radical SAM superfamily 25 186 1.4E-27 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSH58p_14100 fc0c5be5d04afe412bac4278aa385f38 341 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 12 341 5.8E-110 T 14-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_14100 fc0c5be5d04afe412bac4278aa385f38 341 Pfam PF06463 Molybdenum Cofactor Synthesis C 194 320 4.6E-38 T 14-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_14100 fc0c5be5d04afe412bac4278aa385f38 341 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 12 341 39.545 T 14-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_14100 fc0c5be5d04afe412bac4278aa385f38 341 Pfam PF13353 4Fe-4S single cluster domain 28 130 1.2E-8 T 14-10-2018 TSH58p_14100 fc0c5be5d04afe412bac4278aa385f38 341 SMART SM00729 21 229 3.6E-6 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSH58p_14100 fc0c5be5d04afe412bac4278aa385f38 341 SUPERFAMILY SSF102114 11 286 6.93E-80 T 14-10-2018 TSH58p_14100 fc0c5be5d04afe412bac4278aa385f38 341 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 27 38 - T 14-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_12250 16ed656f80ebf893ff4b3d671bf50f68 340 SUPERFAMILY SSF51905 8 316 5.48E-39 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_12250 16ed656f80ebf893ff4b3d671bf50f68 340 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 153 177 2.7E-22 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_12250 16ed656f80ebf893ff4b3d671bf50f68 340 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 208 224 2.7E-22 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_12250 16ed656f80ebf893ff4b3d671bf50f68 340 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 114 122 2.7E-22 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_12250 16ed656f80ebf893ff4b3d671bf50f68 340 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 2.7E-22 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_12250 16ed656f80ebf893ff4b3d671bf50f68 340 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 66 76 2.7E-22 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_12250 16ed656f80ebf893ff4b3d671bf50f68 340 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 281 299 2.7E-22 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_12250 16ed656f80ebf893ff4b3d671bf50f68 340 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 2.2E-14 T 14-10-2018 TSH58p_12250 16ed656f80ebf893ff4b3d671bf50f68 340 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 175 2.2E-14 T 14-10-2018 TSH58p_12250 16ed656f80ebf893ff4b3d671bf50f68 340 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 113 131 2.2E-14 T 14-10-2018 TSH58p_12250 16ed656f80ebf893ff4b3d671bf50f68 340 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 293 2.2E-14 T 14-10-2018 TSH58p_12250 16ed656f80ebf893ff4b3d671bf50f68 340 Gene3D G3DSA:3.50.50.60 9 313 2.8E-98 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_12250 16ed656f80ebf893ff4b3d671bf50f68 340 Hamap MF_01685 Ferredoxin--NADP reductase. 7 334 41.206 T 14-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 TSH58p_12250 16ed656f80ebf893ff4b3d671bf50f68 340 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 296 8.3E-27 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSH58p_12250 16ed656f80ebf893ff4b3d671bf50f68 340 Gene3D G3DSA:3.50.50.60 129 251 2.8E-98 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_08240 91c705e270a43e08f0d151d66c2675bf 331 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 92 2.4E-6 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TSH58p_08240 91c705e270a43e08f0d151d66c2675bf 331 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 6 329 1.2E-123 T 14-10-2018 IPR014188 Acrylyl-CoA reductase AcuI TSH58p_08240 91c705e270a43e08f0d151d66c2675bf 331 SUPERFAMILY SSF51735 121 290 4.1E-34 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_08240 91c705e270a43e08f0d151d66c2675bf 331 SUPERFAMILY SSF50129 5 146 7.46E-39 T 14-10-2018 IPR011032 GroES-like superfamily TSH58p_08240 91c705e270a43e08f0d151d66c2675bf 331 Gene3D G3DSA:3.90.180.10 21 327 3.4E-114 T 14-10-2018 TSH58p_08240 91c705e270a43e08f0d151d66c2675bf 331 SMART SM00829 19 327 1.6E-6 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TSH58p_08240 91c705e270a43e08f0d151d66c2675bf 331 Gene3D G3DSA:3.40.50.720 129 297 3.4E-114 T 14-10-2018 TSH58p_08240 91c705e270a43e08f0d151d66c2675bf 331 Pfam PF00107 Zinc-binding dehydrogenase 163 275 5.7E-10 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TSH58p_11850 97eb66657142fd23f4d0cd2ad594547c 395 Pfam PF06779 Uncharacterised MFS-type transporter YbfB 13 371 2.2E-86 T 14-10-2018 IPR010645 Uncharacterised MFS-type transporter YbfB TSH58p_11850 97eb66657142fd23f4d0cd2ad594547c 395 Gene3D G3DSA:1.20.1250.20 3 380 1.1E-27 T 14-10-2018 TSH58p_11850 97eb66657142fd23f4d0cd2ad594547c 395 SUPERFAMILY SSF103473 4 378 9.29E-39 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_29130 a23593895aab3f4007a1309f4d1f60fa 469 PIRSF PIRSF006446 1 460 8.8E-188 T 14-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 TSH58p_29130 a23593895aab3f4007a1309f4d1f60fa 469 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 8 434 2.8E-159 T 14-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 TSH58p_14050 a15552b5daa9a703b5ed19c7a7d15969 138 Pfam PF00570 HRDC domain 67 129 4.9E-10 T 14-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 TSH58p_14050 a15552b5daa9a703b5ed19c7a7d15969 138 SUPERFAMILY SSF47819 63 133 3.49E-12 T 14-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 TSH58p_14050 a15552b5daa9a703b5ed19c7a7d15969 138 Gene3D G3DSA:1.10.150.80 47 136 4.8E-11 T 14-10-2018 TSH58p_10640 449dee148d2bcf11f614f22f8472e569 300 SMART SM00530 40 111 2.1E-7 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_10640 449dee148d2bcf11f614f22f8472e569 300 Gene3D G3DSA:3.30.450.180 134 298 1.3E-17 T 14-10-2018 TSH58p_10640 449dee148d2bcf11f614f22f8472e569 300 Pfam PF13560 Helix-turn-helix domain 36 114 1.2E-17 T 14-10-2018 TSH58p_10640 449dee148d2bcf11f614f22f8472e569 300 Gene3D G3DSA:1.10.260.40 50 121 4.1E-9 T 14-10-2018 TSH58p_10640 449dee148d2bcf11f614f22f8472e569 300 SUPERFAMILY SSF47413 58 106 7.11E-9 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_07285 76c9e956656981876352f8bd992a7bd6 111 SUPERFAMILY SSF55486 1 74 1.25E-5 T 14-10-2018 TSH58p_12385 e88abcd27166ac0c048391f4f4c1f825 164 SUPERFAMILY SSF51316 25 154 3.31E-52 T 14-10-2018 IPR011057 Mss4-like superfamily TSH58p_12385 e88abcd27166ac0c048391f4f4c1f825 164 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 26 146 1.1E-43 T 14-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 TSH58p_12385 e88abcd27166ac0c048391f4f4c1f825 164 Gene3D G3DSA:2.170.150.20 20 162 9.4E-56 T 14-10-2018 TSH58p_12385 e88abcd27166ac0c048391f4f4c1f825 164 Pfam PF01641 SelR domain 29 144 2.1E-45 T 14-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 TSH58p_27510 e646934ac2a3c96d5e0c1e226e8b60d4 121 Pfam PF00072 Response regulator receiver domain 5 114 2.9E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_27510 e646934ac2a3c96d5e0c1e226e8b60d4 121 SMART SM00448 2 115 8.8E-35 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_27510 e646934ac2a3c96d5e0c1e226e8b60d4 121 SUPERFAMILY SSF52172 4 118 3.7E-35 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_27510 e646934ac2a3c96d5e0c1e226e8b60d4 121 Gene3D G3DSA:3.40.50.12740 3 119 1.2E-35 T 14-10-2018 TSH58p_02630 59e53305a37f98e7b587c47143e365c7 830 Gene3D G3DSA:3.30.200.210 41 668 0.0 T 14-10-2018 TSH58p_02630 59e53305a37f98e7b587c47143e365c7 830 SUPERFAMILY SSF50692 690 828 1.04E-41 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TSH58p_02630 59e53305a37f98e7b587c47143e365c7 830 Pfam PF00384 Molybdopterin oxidoreductase 97 570 9.6E-94 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_02630 59e53305a37f98e7b587c47143e365c7 830 SMART SM00926 40 94 3.2E-11 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_02630 59e53305a37f98e7b587c47143e365c7 830 SUPERFAMILY SSF53706 38 703 7.59E-202 T 14-10-2018 TSH58p_02630 59e53305a37f98e7b587c47143e365c7 830 Gene3D G3DSA:3.40.50.740 97 625 0.0 T 14-10-2018 TSH58p_02630 59e53305a37f98e7b587c47143e365c7 830 Pfam PF01568 Molydopterin dinucleotide binding domain 716 824 4.9E-26 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TSH58p_02630 59e53305a37f98e7b587c47143e365c7 830 TIGRFAM TIGR01706 NAPA: periplasmic nitrate reductase, large subunit 2 830 0.0 T 14-10-2018 IPR010051 Periplasmic nitrate reductase, large subunit GO:0008940|GO:0030151|GO:0042597|GO:0055114 KEGG: 00910+1.9.6.1|MetaCyc: PWY-5674 TSH58p_02630 59e53305a37f98e7b587c47143e365c7 830 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 42 93 3.5E-15 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_02630 59e53305a37f98e7b587c47143e365c7 830 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 45 63 - T 14-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 TSH58p_02630 59e53305a37f98e7b587c47143e365c7 830 Gene3D G3DSA:3.40.228.10 176 705 0.0 T 14-10-2018 TSH58p_02630 59e53305a37f98e7b587c47143e365c7 830 Hamap MF_01630 Periplasmic nitrate reductase [napA]. 1 830 31.897 T 14-10-2018 IPR010051 Periplasmic nitrate reductase, large subunit GO:0008940|GO:0030151|GO:0042597|GO:0055114 KEGG: 00910+1.9.6.1|MetaCyc: PWY-5674 TSH58p_02630 59e53305a37f98e7b587c47143e365c7 830 Gene3D G3DSA:2.40.40.20 706 830 4.0E-47 T 14-10-2018 TSH58p_02630 59e53305a37f98e7b587c47143e365c7 830 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 2 28 5.2E-5 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal TSH58p_16530 dafc66097d1ffbec5f6b224f7e2505cd 677 SUPERFAMILY SSF63829 329 629 5.69E-9 T 14-10-2018 TSH58p_16530 dafc66097d1ffbec5f6b224f7e2505cd 677 Pfam PF05787 Bacterial protein of unknown function (DUF839) 87 626 4.6E-191 T 14-10-2018 IPR008557 Protein of unknown function DUF839 TSH58p_17275 614086482d4ed32e504c308c541eb1d9 190 Gene3D G3DSA:1.10.940.10 23 177 1.2E-33 T 14-10-2018 IPR035926 NusB-like superfamily TSH58p_17275 614086482d4ed32e504c308c541eb1d9 190 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 27 173 18.358 T 14-10-2018 IPR011605 NusB antitermination factor GO:0006353 TSH58p_17275 614086482d4ed32e504c308c541eb1d9 190 SUPERFAMILY SSF48013 28 175 2.22E-27 T 14-10-2018 IPR035926 NusB-like superfamily TSH58p_17275 614086482d4ed32e504c308c541eb1d9 190 Pfam PF01029 NusB family 31 170 2.1E-25 T 14-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 TSH58p_17275 614086482d4ed32e504c308c541eb1d9 190 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 29 171 1.0E-31 T 14-10-2018 IPR011605 NusB antitermination factor GO:0006353 TSH58p_31635 20ef941e0863191b4564e473642987ab 327 Gene3D G3DSA:3.40.1570.10 27 263 1.3E-90 T 14-10-2018 TSH58p_31635 20ef941e0863191b4564e473642987ab 327 SUPERFAMILY SSF144064 27 321 7.75E-81 T 14-10-2018 TSH58p_31635 20ef941e0863191b4564e473642987ab 327 Pfam PF05171 Haemin-degrading HemS.ChuX domain 27 133 4.9E-22 T 14-10-2018 IPR007845 Haemin-degrading HemS/ChuX domain GO:0006826 TSH58p_31635 20ef941e0863191b4564e473642987ab 327 Pfam PF05171 Haemin-degrading HemS.ChuX domain 188 320 1.4E-24 T 14-10-2018 IPR007845 Haemin-degrading HemS/ChuX domain GO:0006826 TSH58p_31635 20ef941e0863191b4564e473642987ab 327 Gene3D G3DSA:3.40.1570.10 65 316 1.3E-90 T 14-10-2018 TSH58p_05845 32d0fdc38e3797823e3b8c1cfefe9e3e 264 SUPERFAMILY SSF50037 214 258 3.3E-5 T 14-10-2018 IPR008988 Transcriptional repressor, C-terminal TSH58p_05845 32d0fdc38e3797823e3b8c1cfefe9e3e 264 Gene3D G3DSA:2.30.30.100 212 258 5.5E-8 T 14-10-2018 TSH58p_05845 32d0fdc38e3797823e3b8c1cfefe9e3e 264 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 20 256 1.6E-46 T 14-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TSH58p_05845 32d0fdc38e3797823e3b8c1cfefe9e3e 264 Pfam PF16917 Biotin/lipoate A/B protein ligase family 68 206 7.0E-18 T 14-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 TSH58p_05845 32d0fdc38e3797823e3b8c1cfefe9e3e 264 Pfam PF02237 Biotin protein ligase C terminal domain 212 258 5.3E-9 T 14-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TSH58p_05845 32d0fdc38e3797823e3b8c1cfefe9e3e 264 SUPERFAMILY SSF55681 12 208 1.37E-53 T 14-10-2018 TSH58p_05845 32d0fdc38e3797823e3b8c1cfefe9e3e 264 Gene3D G3DSA:3.30.930.10 25 210 1.3E-55 T 14-10-2018 TSH58p_21240 0cc17275e74e98c225d5501bb4e0d0e6 393 Pfam PF00155 Aminotransferase class I and II 42 384 2.1E-58 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSH58p_21240 0cc17275e74e98c225d5501bb4e0d0e6 393 Gene3D G3DSA:3.90.1150.10 42 382 1.0E-127 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_21240 0cc17275e74e98c225d5501bb4e0d0e6 393 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 21 385 4.4E-131 T 14-10-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 TSH58p_21240 0cc17275e74e98c225d5501bb4e0d0e6 393 Gene3D G3DSA:3.40.640.10 58 292 1.0E-127 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_21240 0cc17275e74e98c225d5501bb4e0d0e6 393 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 241 250 - T 14-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 TSH58p_21240 0cc17275e74e98c225d5501bb4e0d0e6 393 SUPERFAMILY SSF53383 5 390 8.78E-105 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_19705 cd5952b1ed7572cb5533fb3cf8518d88 302 SUPERFAMILY SSF52210 121 288 1.96E-42 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSH58p_19705 cd5952b1ed7572cb5533fb3cf8518d88 302 PRINTS PR01798 Succinyl-CoA synthase signature 80 97 2.3E-28 T 14-10-2018 TSH58p_19705 cd5952b1ed7572cb5533fb3cf8518d88 302 PRINTS PR01798 Succinyl-CoA synthase signature 178 196 2.3E-28 T 14-10-2018 TSH58p_19705 cd5952b1ed7572cb5533fb3cf8518d88 302 PRINTS PR01798 Succinyl-CoA synthase signature 209 222 2.3E-28 T 14-10-2018 TSH58p_19705 cd5952b1ed7572cb5533fb3cf8518d88 302 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 2.3E-28 T 14-10-2018 TSH58p_19705 cd5952b1ed7572cb5533fb3cf8518d88 302 PIRSF PIRSF001553 1 291 1.6E-100 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSH58p_19705 cd5952b1ed7572cb5533fb3cf8518d88 302 Gene3D G3DSA:3.40.50.261 122 289 2.9E-53 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSH58p_19705 cd5952b1ed7572cb5533fb3cf8518d88 302 Gene3D G3DSA:3.40.50.720 1 121 3.9E-45 T 14-10-2018 TSH58p_19705 cd5952b1ed7572cb5533fb3cf8518d88 302 SMART SM00881 2 98 2.4E-25 T 14-10-2018 IPR003781 CoA-binding GO:0048037 TSH58p_19705 cd5952b1ed7572cb5533fb3cf8518d88 302 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 288 33.387 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSH58p_19705 cd5952b1ed7572cb5533fb3cf8518d88 302 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 146 284 3.6E-12 T 14-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain TSH58p_19705 cd5952b1ed7572cb5533fb3cf8518d88 302 Pfam PF02629 CoA binding domain 5 97 1.2E-23 T 14-10-2018 IPR003781 CoA-binding GO:0048037 TSH58p_19705 cd5952b1ed7572cb5533fb3cf8518d88 302 SUPERFAMILY SSF51735 3 120 3.52E-37 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_26100 48dfa2f44d84e9d18f4001548637378c 252 SMART SM00382 26 213 5.4E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_26100 48dfa2f44d84e9d18f4001548637378c 252 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_26100 48dfa2f44d84e9d18f4001548637378c 252 Gene3D G3DSA:3.40.50.300 1 251 1.2E-67 T 14-10-2018 TSH58p_26100 48dfa2f44d84e9d18f4001548637378c 252 SUPERFAMILY SSF52540 2 225 2.83E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_26100 48dfa2f44d84e9d18f4001548637378c 252 Pfam PF00005 ABC transporter 18 164 2.1E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_18635 27d3752ac6f9678a3a4368ba0738044b 846 Pfam PF08521 Two-component sensor kinase N-terminal 21 171 3.3E-39 T 14-10-2018 IPR013727 Two-component sensor kinase, N-terminal TSH58p_18635 27d3752ac6f9678a3a4368ba0738044b 846 Pfam PF13343 Bacterial extracellular solute-binding protein 577 789 1.0E-15 T 14-10-2018 TSH58p_18635 27d3752ac6f9678a3a4368ba0738044b 846 Gene3D G3DSA:3.40.190.10 625 840 3.2E-130 T 14-10-2018 TSH58p_18635 27d3752ac6f9678a3a4368ba0738044b 846 Gene3D G3DSA:1.10.287.130 199 312 1.9E-15 T 14-10-2018 TSH58p_18635 27d3752ac6f9678a3a4368ba0738044b 846 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 358 467 1.9E-17 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_18635 27d3752ac6f9678a3a4368ba0738044b 846 SUPERFAMILY SSF47384 230 307 8.63E-13 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_18635 27d3752ac6f9678a3a4368ba0738044b 846 SMART SM00388 247 312 2.0E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_18635 27d3752ac6f9678a3a4368ba0738044b 846 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 411 9.9E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_18635 27d3752ac6f9678a3a4368ba0738044b 846 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 448 9.9E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_18635 27d3752ac6f9678a3a4368ba0738044b 846 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 467 9.9E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_18635 27d3752ac6f9678a3a4368ba0738044b 846 Gene3D G3DSA:3.30.565.10 317 472 6.1E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_18635 27d3752ac6f9678a3a4368ba0738044b 846 SUPERFAMILY SSF53850 516 798 7.48E-42 T 14-10-2018 TSH58p_18635 27d3752ac6f9678a3a4368ba0738044b 846 SMART SM00387 358 470 1.4E-27 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_18635 27d3752ac6f9678a3a4368ba0738044b 846 SUPERFAMILY SSF55874 302 468 7.99E-33 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_18635 27d3752ac6f9678a3a4368ba0738044b 846 Pfam PF00512 His Kinase A (phospho-acceptor) domain 248 305 3.9E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_18635 27d3752ac6f9678a3a4368ba0738044b 846 Gene3D G3DSA:3.40.190.10 516 827 3.2E-130 T 14-10-2018 TSH58p_12680 5b0d7da0c905083b023e856c9b30ceef 885 SMART SM00086 307 348 6.3E-4 T 14-10-2018 IPR001610 PAC motif TSH58p_12680 5b0d7da0c905083b023e856c9b30ceef 885 SUPERFAMILY SSF52172 613 733 2.13E-34 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_12680 5b0d7da0c905083b023e856c9b30ceef 885 Pfam PF00072 Response regulator receiver domain 616 728 4.3E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_12680 5b0d7da0c905083b023e856c9b30ceef 885 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 250 355 6.3E-8 T 14-10-2018 IPR000014 PAS domain TSH58p_12680 5b0d7da0c905083b023e856c9b30ceef 885 Pfam PF07694 5TMR of 5TMR-LYT 66 213 4.3E-22 T 14-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 TSH58p_12680 5b0d7da0c905083b023e856c9b30ceef 885 SMART SM00388 368 433 1.7E-21 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_12680 5b0d7da0c905083b023e856c9b30ceef 885 Gene3D G3DSA:3.30.565.10 432 593 4.6E-49 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_12680 5b0d7da0c905083b023e856c9b30ceef 885 Gene3D G3DSA:3.30.450.20 228 344 3.4E-26 T 14-10-2018 TSH58p_12680 5b0d7da0c905083b023e856c9b30ceef 885 SUPERFAMILY SSF47384 353 434 1.63E-19 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_12680 5b0d7da0c905083b023e856c9b30ceef 885 PRINTS PR00344 Bacterial sensor protein C-terminal signature 576 589 6.6E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_12680 5b0d7da0c905083b023e856c9b30ceef 885 PRINTS PR00344 Bacterial sensor protein C-terminal signature 552 570 6.6E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_12680 5b0d7da0c905083b023e856c9b30ceef 885 PRINTS PR00344 Bacterial sensor protein C-terminal signature 521 535 6.6E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_12680 5b0d7da0c905083b023e856c9b30ceef 885 PRINTS PR00344 Bacterial sensor protein C-terminal signature 539 549 6.6E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_12680 5b0d7da0c905083b023e856c9b30ceef 885 Gene3D G3DSA:1.20.120.160 753 869 1.3E-9 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_12680 5b0d7da0c905083b023e856c9b30ceef 885 SUPERFAMILY SSF47226 756 865 1.5E-9 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_12680 5b0d7da0c905083b023e856c9b30ceef 885 Pfam PF08447 PAS fold 258 339 8.0E-17 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 TSH58p_12680 5b0d7da0c905083b023e856c9b30ceef 885 Gene3D G3DSA:1.10.287.130 345 431 7.1E-27 T 14-10-2018 TSH58p_12680 5b0d7da0c905083b023e856c9b30ceef 885 SUPERFAMILY SSF55874 422 588 6.42E-46 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_12680 5b0d7da0c905083b023e856c9b30ceef 885 Pfam PF00512 His Kinase A (phospho-acceptor) domain 368 433 9.4E-18 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_12680 5b0d7da0c905083b023e856c9b30ceef 885 SUPERFAMILY SSF55785 217 346 1.92E-19 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_12680 5b0d7da0c905083b023e856c9b30ceef 885 SMART SM00387 480 592 3.0E-36 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_12680 5b0d7da0c905083b023e856c9b30ceef 885 Gene3D G3DSA:3.40.50.2300 612 747 9.7E-35 T 14-10-2018 TSH58p_12680 5b0d7da0c905083b023e856c9b30ceef 885 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 480 590 6.2E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_12680 5b0d7da0c905083b023e856c9b30ceef 885 SMART SM00448 614 728 1.1E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_32355 ab34f21187eea86c4696f79557e7095f 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 140 304 5.1E-9 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_32355 ab34f21187eea86c4696f79557e7095f 310 Gene3D G3DSA:1.10.3720.10 32 307 4.5E-59 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_32355 ab34f21187eea86c4696f79557e7095f 310 SUPERFAMILY SSF161098 28 304 2.8E-55 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_02355 509c32ca4b80690221e2ca98d580fb5d 500 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 19 495 1.5E-121 T 14-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 TSH58p_02355 509c32ca4b80690221e2ca98d580fb5d 500 Gene3D G3DSA:1.20.1600.10 79 495 9.0E-125 T 14-10-2018 TSH58p_02355 509c32ca4b80690221e2ca98d580fb5d 500 Gene3D G3DSA:2.20.200.10 126 385 9.0E-125 T 14-10-2018 TSH58p_02355 509c32ca4b80690221e2ca98d580fb5d 500 SUPERFAMILY SSF56954 6 498 9.02E-107 T 14-10-2018 TSH58p_02355 509c32ca4b80690221e2ca98d580fb5d 500 Pfam PF02321 Outer membrane efflux protein 89 287 8.0E-31 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 TSH58p_02355 509c32ca4b80690221e2ca98d580fb5d 500 Pfam PF02321 Outer membrane efflux protein 314 494 1.1E-22 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 TSH58p_10450 9e90bbf36213b8e9dafd52086100b636 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 312 3.0E-35 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_10450 9e90bbf36213b8e9dafd52086100b636 315 SUPERFAMILY SSF161098 91 297 6.8E-21 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_10450 9e90bbf36213b8e9dafd52086100b636 315 Gene3D G3DSA:1.10.3720.10 84 307 2.6E-25 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_20210 5c6b4e68c6a47d5b47a30586f3f99003 376 SUPERFAMILY SSF103039 87 271 1.91E-8 T 14-10-2018 IPR028976 CheC-like superfamily TSH58p_20210 5c6b4e68c6a47d5b47a30586f3f99003 376 PIRSF PIRSF002888 48 370 2.6E-78 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 TSH58p_20210 5c6b4e68c6a47d5b47a30586f3f99003 376 Pfam PF02154 Flagellar motor switch protein FliM 84 271 2.8E-52 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 TSH58p_20210 5c6b4e68c6a47d5b47a30586f3f99003 376 PRINTS PR00955 Flagellar motor switch protein FliM signature 253 271 4.3E-16 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 TSH58p_20210 5c6b4e68c6a47d5b47a30586f3f99003 376 PRINTS PR00955 Flagellar motor switch protein FliM signature 49 62 4.3E-16 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 TSH58p_20210 5c6b4e68c6a47d5b47a30586f3f99003 376 PRINTS PR00955 Flagellar motor switch protein FliM signature 130 146 4.3E-16 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 TSH58p_20210 5c6b4e68c6a47d5b47a30586f3f99003 376 PRINTS PR00955 Flagellar motor switch protein FliM signature 155 174 4.3E-16 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 TSH58p_20210 5c6b4e68c6a47d5b47a30586f3f99003 376 Gene3D G3DSA:3.40.1550.10 85 272 7.4E-46 T 14-10-2018 IPR028976 CheC-like superfamily TSH58p_20210 5c6b4e68c6a47d5b47a30586f3f99003 376 SUPERFAMILY SSF101801 290 368 1.31E-10 T 14-10-2018 IPR036429 SpoA-like superfamily TSH58p_20210 5c6b4e68c6a47d5b47a30586f3f99003 376 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 52 362 4.1E-73 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 TSH58p_20210 5c6b4e68c6a47d5b47a30586f3f99003 376 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 293 360 6.9E-14 T 14-10-2018 IPR001543 Surface presentation of antigen (SpoA) TSH58p_02105 2eda607f46445dce143343716f069a5c 153 Gene3D G3DSA:3.40.1260.10 33 153 4.5E-28 T 14-10-2018 IPR027396 DsrEFH-like TSH58p_02105 2eda607f46445dce143343716f069a5c 153 SUPERFAMILY SSF75169 34 153 7.3E-20 T 14-10-2018 IPR027396 DsrEFH-like TSH58p_00245 1faa5b564bd4f4981fa4255d69775c07 252 SUPERFAMILY SSF46785 12 86 5.22E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_00245 1faa5b564bd4f4981fa4255d69775c07 252 SMART SM00895 92 216 1.4E-18 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_00245 1faa5b564bd4f4981fa4255d69775c07 252 Pfam PF07729 FCD domain 98 213 8.3E-26 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_00245 1faa5b564bd4f4981fa4255d69775c07 252 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 1.2E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_00245 1faa5b564bd4f4981fa4255d69775c07 252 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 1.2E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_00245 1faa5b564bd4f4981fa4255d69775c07 252 SMART SM00345 21 82 2.5E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_00245 1faa5b564bd4f4981fa4255d69775c07 252 Gene3D G3DSA:1.10.10.10 14 83 5.9E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_00245 1faa5b564bd4f4981fa4255d69775c07 252 Gene3D G3DSA:1.20.120.530 86 220 5.7E-28 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_00245 1faa5b564bd4f4981fa4255d69775c07 252 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 82 7.7E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_00245 1faa5b564bd4f4981fa4255d69775c07 252 SUPERFAMILY SSF48008 89 221 1.36E-25 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_08605 6aa8a8b56127af84fd5b42fc8ccc2555 429 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 333 425 8.8E-28 T 14-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSH58p_08605 6aa8a8b56127af84fd5b42fc8ccc2555 429 SMART SM01209 101 298 1.6E-130 T 14-10-2018 TSH58p_08605 6aa8a8b56127af84fd5b42fc8ccc2555 429 SMART SM01210 332 427 1.6E-53 T 14-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSH58p_08605 6aa8a8b56127af84fd5b42fc8ccc2555 429 Gene3D G3DSA:3.30.470.20 189 331 1.4E-55 T 14-10-2018 TSH58p_08605 6aa8a8b56127af84fd5b42fc8ccc2555 429 SUPERFAMILY SSF52440 1 101 5.32E-35 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TSH58p_08605 6aa8a8b56127af84fd5b42fc8ccc2555 429 Gene3D G3DSA:3.90.600.10 332 428 5.1E-32 T 14-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSH58p_08605 6aa8a8b56127af84fd5b42fc8ccc2555 429 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 298 1.7E-79 T 14-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSH58p_08605 6aa8a8b56127af84fd5b42fc8ccc2555 429 SUPERFAMILY SSF51246 331 427 3.3E-31 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TSH58p_08605 6aa8a8b56127af84fd5b42fc8ccc2555 429 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 427 42.41 T 14-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSH58p_08605 6aa8a8b56127af84fd5b42fc8ccc2555 429 Gene3D G3DSA:3.40.50.20 2 93 1.1E-35 T 14-10-2018 TSH58p_08605 6aa8a8b56127af84fd5b42fc8ccc2555 429 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 292 299 - T 14-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSH58p_08605 6aa8a8b56127af84fd5b42fc8ccc2555 429 Gene3D G3DSA:3.30.1490.20 119 188 5.1E-26 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSH58p_08605 6aa8a8b56127af84fd5b42fc8ccc2555 429 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 3.1E-34 T 14-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSH58p_08605 6aa8a8b56127af84fd5b42fc8ccc2555 429 SUPERFAMILY SSF56059 102 325 4.95E-63 T 14-10-2018 TSH58p_08605 6aa8a8b56127af84fd5b42fc8ccc2555 429 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 427 2.4E-165 T 14-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSH58p_08090 880cc3036be90fbf2aa9122afdac3ddd 530 Gene3D G3DSA:3.40.50.1820 93 317 6.6E-19 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_08090 880cc3036be90fbf2aa9122afdac3ddd 530 SUPERFAMILY SSF53474 65 516 1.94E-70 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_08090 880cc3036be90fbf2aa9122afdac3ddd 530 Pfam PF00450 Serine carboxypeptidase 112 492 1.5E-16 T 14-10-2018 IPR001563 Peptidase S10, serine carboxypeptidase GO:0004185|GO:0006508 TSH58p_08090 880cc3036be90fbf2aa9122afdac3ddd 530 Gene3D G3DSA:3.40.50.1820 366 528 3.2E-5 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_08090 880cc3036be90fbf2aa9122afdac3ddd 530 ProSitePatterns PS00131 Serine carboxypeptidases, serine active site. 232 239 - T 14-10-2018 IPR018202 Serine carboxypeptidase, serine active site TSH58p_06140 249f9c79843bcb50930b39994c50fa6e 301 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 169 235 2.8E-22 T 14-10-2018 IPR017703 YgfZ/GcvT conserved site TSH58p_06140 249f9c79843bcb50930b39994c50fa6e 301 SUPERFAMILY SSF103025 3 224 2.04E-57 T 14-10-2018 TSH58p_06140 249f9c79843bcb50930b39994c50fa6e 301 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 210 279 3.9E-9 T 14-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 TSH58p_06140 249f9c79843bcb50930b39994c50fa6e 301 Pfam PF01571 Aminomethyltransferase folate-binding domain 15 113 4.1E-11 T 14-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain TSH58p_06140 249f9c79843bcb50930b39994c50fa6e 301 Gene3D G3DSA:3.30.1360.120 1 294 2.2E-61 T 14-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 TSH58p_06140 249f9c79843bcb50930b39994c50fa6e 301 PIRSF PIRSF006487 150 269 0.0086 T 14-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 TSH58p_06140 249f9c79843bcb50930b39994c50fa6e 301 PIRSF PIRSF006487 2 118 1.8E-9 T 14-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 TSH58p_30770 9efea37de452cef9a696fb60ea67bc9b 296 Gene3D G3DSA:3.40.50.300 10 286 5.6E-77 T 14-10-2018 TSH58p_30770 9efea37de452cef9a696fb60ea67bc9b 296 SUPERFAMILY SSF52540 12 256 5.09E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_30770 9efea37de452cef9a696fb60ea67bc9b 296 Pfam PF00005 ABC transporter 29 185 6.5E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_30770 9efea37de452cef9a696fb60ea67bc9b 296 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_30770 9efea37de452cef9a696fb60ea67bc9b 296 SMART SM00382 37 235 4.0E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_30760 41d8a706d1d609bd49fdc732309111e7 534 Gene3D G3DSA:3.90.76.10 58 195 6.2E-130 T 14-10-2018 TSH58p_30760 41d8a706d1d609bd49fdc732309111e7 534 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 443 7.6E-89 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain TSH58p_30760 41d8a706d1d609bd49fdc732309111e7 534 Gene3D G3DSA:3.40.190.10 196 513 6.2E-130 T 14-10-2018 TSH58p_30760 41d8a706d1d609bd49fdc732309111e7 534 Gene3D G3DSA:3.10.105.10 273 504 6.2E-130 T 14-10-2018 TSH58p_30760 41d8a706d1d609bd49fdc732309111e7 534 SUPERFAMILY SSF53850 32 530 3.44E-131 T 14-10-2018 TSH58p_30760 41d8a706d1d609bd49fdc732309111e7 534 PIRSF PIRSF002741 3 532 1.3E-129 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 553 671 4.6E-13 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 Pfam PF13188 PAS domain 318 364 6.1E-6 T 14-10-2018 IPR000014 PAS domain TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 SUPERFAMILY SSF55785 288 424 9.07E-11 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 Pfam PF12860 PAS fold 181 296 2.1E-17 T 14-10-2018 TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 SUPERFAMILY SSF47384 434 504 3.34E-11 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 Gene3D G3DSA:1.10.287.130 436 505 7.8E-19 T 14-10-2018 TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 Gene3D G3DSA:3.30.450.20 304 435 1.8E-12 T 14-10-2018 TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 Gene3D G3DSA:3.30.450.20 169 303 2.3E-8 T 14-10-2018 TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 Gene3D G3DSA:3.40.50.2300 688 812 7.6E-30 T 14-10-2018 TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 SMART SM00448 693 806 7.4E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 SUPERFAMILY SSF55874 497 673 6.68E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 SMART SM00387 549 673 3.1E-26 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 SMART SM00388 441 507 1.3E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 Gene3D G3DSA:3.30.565.10 509 677 1.3E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 Gene3D G3DSA:3.30.450.20 38 161 2.4E-17 T 14-10-2018 TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 PRINTS PR00344 Bacterial sensor protein C-terminal signature 601 615 1.3E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 PRINTS PR00344 Bacterial sensor protein C-terminal signature 632 650 1.3E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 PRINTS PR00344 Bacterial sensor protein C-terminal signature 657 670 1.3E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 PRINTS PR00344 Bacterial sensor protein C-terminal signature 619 629 1.3E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 314 433 7.8E-11 T 14-10-2018 IPR000014 PAS domain TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 SMART SM00091 48 115 1.8 T 14-10-2018 IPR000014 PAS domain TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 SMART SM00091 175 242 120.0 T 14-10-2018 IPR000014 PAS domain TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 SMART SM00091 317 383 41.0 T 14-10-2018 IPR000014 PAS domain TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 Pfam PF08448 PAS fold 65 163 3.5E-5 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 SUPERFAMILY SSF52172 693 811 2.7E-31 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 SMART SM00086 121 163 0.52 T 14-10-2018 IPR001610 PAC motif TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 SMART SM00086 386 426 5.1 T 14-10-2018 IPR001610 PAC motif TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 Pfam PF00072 Response regulator receiver domain 695 807 8.5E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 SUPERFAMILY SSF55785 37 157 2.44E-16 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_05390 153d96110f6cea58b246752e8be6e7c6 812 Pfam PF00512 His Kinase A (phospho-acceptor) domain 442 504 5.2E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_31875 025fae3130cc9e17926ba411d238fcb0 335 SUPERFAMILY SSF50331 259 331 7.23E-7 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSH58p_31875 025fae3130cc9e17926ba411d238fcb0 335 Pfam PF08402 TOBE domain 266 331 1.2E-7 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TSH58p_31875 025fae3130cc9e17926ba411d238fcb0 335 Pfam PF00005 ABC transporter 18 160 1.9E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_31875 025fae3130cc9e17926ba411d238fcb0 335 SUPERFAMILY SSF52540 3 241 1.09E-84 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_31875 025fae3130cc9e17926ba411d238fcb0 335 Gene3D G3DSA:3.40.50.300 1 237 1.7E-74 T 14-10-2018 TSH58p_31875 025fae3130cc9e17926ba411d238fcb0 335 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_31875 025fae3130cc9e17926ba411d238fcb0 335 SMART SM00382 27 210 3.9E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_19320 05a78efcebb50d168db79f376a2ae9c9 389 Hamap MF_01643 Formate-dependent phosphoribosylglycinamide formyltransferase [purT]. 1 387 50.106 T 14-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 TSH58p_19320 05a78efcebb50d168db79f376a2ae9c9 389 SUPERFAMILY SSF52440 5 103 5.61E-30 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TSH58p_19320 05a78efcebb50d168db79f376a2ae9c9 389 SUPERFAMILY SSF51246 310 386 2.67E-17 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TSH58p_19320 05a78efcebb50d168db79f376a2ae9c9 389 SUPERFAMILY SSF56059 104 306 3.01E-58 T 14-10-2018 TSH58p_19320 05a78efcebb50d168db79f376a2ae9c9 389 Pfam PF02222 ATP-grasp domain 115 285 6.4E-56 T 14-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type TSH58p_19320 05a78efcebb50d168db79f376a2ae9c9 389 Gene3D G3DSA:3.30.470.20 188 386 1.0E-62 T 14-10-2018 TSH58p_19320 05a78efcebb50d168db79f376a2ae9c9 389 Gene3D G3DSA:3.40.50.20 2 114 1.5E-46 T 14-10-2018 TSH58p_19320 05a78efcebb50d168db79f376a2ae9c9 389 Gene3D G3DSA:3.30.1490.20 115 187 2.0E-28 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSH58p_19320 05a78efcebb50d168db79f376a2ae9c9 389 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 5 386 4.6E-170 T 14-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 TSH58p_01330 3e57fb7b7f81cb9569201dd82ff1c623 567 Gene3D G3DSA:3.40.50.300 317 567 1.0E-61 T 14-10-2018 TSH58p_01330 3e57fb7b7f81cb9569201dd82ff1c623 567 SUPERFAMILY SSF52540 315 560 1.98E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_01330 3e57fb7b7f81cb9569201dd82ff1c623 567 Pfam PF02653 Branched-chain amino acid transport system / permease component 4 275 4.2E-45 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_01330 3e57fb7b7f81cb9569201dd82ff1c623 567 Pfam PF00005 ABC transporter 337 496 1.0E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_01330 3e57fb7b7f81cb9569201dd82ff1c623 567 SMART SM00382 345 544 5.6E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_19815 6e1e4ad4b640597cbd49b259a7774646 555 Gene3D G3DSA:3.40.50.2300 431 554 2.9E-22 T 14-10-2018 TSH58p_19815 6e1e4ad4b640597cbd49b259a7774646 555 SUPERFAMILY SSF47384 172 243 8.63E-9 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_19815 6e1e4ad4b640597cbd49b259a7774646 555 SUPERFAMILY SSF52172 433 551 2.13E-24 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_19815 6e1e4ad4b640597cbd49b259a7774646 555 Gene3D G3DSA:3.30.565.10 248 413 2.7E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_19815 6e1e4ad4b640597cbd49b259a7774646 555 SMART SM00387 287 410 1.6E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_19815 6e1e4ad4b640597cbd49b259a7774646 555 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 288 408 5.0E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_19815 6e1e4ad4b640597cbd49b259a7774646 555 SMART SM00388 180 246 1.5E-4 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_19815 6e1e4ad4b640597cbd49b259a7774646 555 Pfam PF00512 His Kinase A (phospho-acceptor) domain 181 244 6.2E-7 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_19815 6e1e4ad4b640597cbd49b259a7774646 555 Gene3D G3DSA:1.10.287.130 172 244 5.0E-20 T 14-10-2018 TSH58p_19815 6e1e4ad4b640597cbd49b259a7774646 555 Pfam PF00072 Response regulator receiver domain 436 546 1.3E-14 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_19815 6e1e4ad4b640597cbd49b259a7774646 555 SUPERFAMILY SSF55874 237 408 3.93E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_19815 6e1e4ad4b640597cbd49b259a7774646 555 SUPERFAMILY SSF52172 4 132 6.55E-8 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_19815 6e1e4ad4b640597cbd49b259a7774646 555 SMART SM00448 434 546 1.6E-13 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_19815 6e1e4ad4b640597cbd49b259a7774646 555 PRINTS PR00344 Bacterial sensor protein C-terminal signature 370 388 1.4E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_19815 6e1e4ad4b640597cbd49b259a7774646 555 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 367 1.4E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_19815 6e1e4ad4b640597cbd49b259a7774646 555 PRINTS PR00344 Bacterial sensor protein C-terminal signature 339 353 1.4E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_19815 6e1e4ad4b640597cbd49b259a7774646 555 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 407 1.4E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_04050 c2a2730a87633e2f23267a3089cfe337 318 PIRSF PIRSF000446 1 318 1.3E-93 T 14-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 TSH58p_04050 c2a2730a87633e2f23267a3089cfe337 318 SUPERFAMILY SSF55048 131 205 1.16E-14 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TSH58p_04050 c2a2730a87633e2f23267a3089cfe337 318 SUPERFAMILY SSF52151 3 316 1.31E-77 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TSH58p_04050 c2a2730a87633e2f23267a3089cfe337 318 Pfam PF00698 Acyl transferase domain 5 283 2.5E-37 T 14-10-2018 IPR014043 Acyl transferase TSH58p_04050 c2a2730a87633e2f23267a3089cfe337 318 Gene3D G3DSA:3.30.70.250 130 207 1.8E-98 T 14-10-2018 TSH58p_04050 c2a2730a87633e2f23267a3089cfe337 318 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6 308 1.8E-47 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TSH58p_04050 c2a2730a87633e2f23267a3089cfe337 318 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 299 3.3E-96 T 14-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 TSH58p_04050 c2a2730a87633e2f23267a3089cfe337 318 Gene3D G3DSA:3.40.366.10 5 294 1.8E-98 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TSH58p_23010 4566c2627a9d97a4d26195f31b341b49 265 SUPERFAMILY SSF52540 29 231 1.52E-30 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_23010 4566c2627a9d97a4d26195f31b341b49 265 Gene3D G3DSA:3.40.50.300 18 185 1.2E-29 T 14-10-2018 TSH58p_23010 4566c2627a9d97a4d26195f31b341b49 265 Pfam PF07728 AAA domain (dynein-related subfamily) 33 167 3.6E-31 T 14-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 TSH58p_23010 4566c2627a9d97a4d26195f31b341b49 265 Pfam PF08406 CbbQ/NirQ/NorQ C-terminal 180 262 3.6E-29 T 14-10-2018 IPR013615 CbbQ/NirQ/NorQ, C-terminal TSH58p_32270 7e120bfbf12eb47f4470927759a03ca8 89 Gene3D G3DSA:3.40.1620.10 1 39 3.2E-10 T 14-10-2018 TSH58p_32270 7e120bfbf12eb47f4470927759a03ca8 89 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 52 2.9E-8 T 14-10-2018 TSH58p_32270 7e120bfbf12eb47f4470927759a03ca8 89 SUPERFAMILY SSF143120 1 43 1.14E-9 T 14-10-2018 IPR036165 YefM-like superfamily TSH58p_32270 7e120bfbf12eb47f4470927759a03ca8 89 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 2 42 7.7E-9 T 14-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM TSH58p_23385 2b04b9d7c1c479f2eb0c83799d162909 872 Gene3D G3DSA:1.10.1780.10 1 159 1.2E-29 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 TSH58p_23385 2b04b9d7c1c479f2eb0c83799d162909 872 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 600 618 1.1E-31 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 TSH58p_23385 2b04b9d7c1c479f2eb0c83799d162909 872 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 645 663 1.1E-31 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 TSH58p_23385 2b04b9d7c1c479f2eb0c83799d162909 872 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 707 721 1.1E-31 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 TSH58p_23385 2b04b9d7c1c479f2eb0c83799d162909 872 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 674 692 1.1E-31 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 TSH58p_23385 2b04b9d7c1c479f2eb0c83799d162909 872 Gene3D G3DSA:3.40.50.300 373 543 1.6E-41 T 14-10-2018 TSH58p_23385 2b04b9d7c1c479f2eb0c83799d162909 872 SMART SM00382 223 368 1.9E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_23385 2b04b9d7c1c479f2eb0c83799d162909 872 SMART SM00382 596 738 1.7E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_23385 2b04b9d7c1c479f2eb0c83799d162909 872 SUPERFAMILY SSF52540 185 510 1.37E-71 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_23385 2b04b9d7c1c479f2eb0c83799d162909 872 SUPERFAMILY SSF81923 16 127 1.27E-12 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 TSH58p_23385 2b04b9d7c1c479f2eb0c83799d162909 872 Gene3D G3DSA:1.10.8.60 772 868 7.1E-11 T 14-10-2018 TSH58p_23385 2b04b9d7c1c479f2eb0c83799d162909 872 Pfam PF07724 AAA domain (Cdc48 subfamily) 595 766 1.3E-38 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSH58p_23385 2b04b9d7c1c479f2eb0c83799d162909 872 Gene3D G3DSA:3.40.50.300 183 372 4.1E-62 T 14-10-2018 TSH58p_23385 2b04b9d7c1c479f2eb0c83799d162909 872 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 26 74 8.8E-6 T 14-10-2018 IPR004176 Clp, N-terminal TSH58p_23385 2b04b9d7c1c479f2eb0c83799d162909 872 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 319 331 - T 14-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 TSH58p_23385 2b04b9d7c1c479f2eb0c83799d162909 872 SUPERFAMILY SSF52540 545 831 9.58E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_23385 2b04b9d7c1c479f2eb0c83799d162909 872 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 772 845 3.2E-12 T 14-10-2018 IPR019489 Clp ATPase, C-terminal TSH58p_23385 2b04b9d7c1c479f2eb0c83799d162909 872 Gene3D G3DSA:3.40.50.300 549 770 3.7E-66 T 14-10-2018 TSH58p_23385 2b04b9d7c1c479f2eb0c83799d162909 872 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 228 340 2.2E-8 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSH58p_23385 2b04b9d7c1c479f2eb0c83799d162909 872 TIGRFAM TIGR03345 VI_ClpV1: type VI secretion ATPase, ClpV1 family 12 856 0.0 T 14-10-2018 IPR017729 Type VI secretion system, ATPase ClpV1 TSH58p_23385 2b04b9d7c1c479f2eb0c83799d162909 872 SMART SM01086 772 865 2.1E-9 T 14-10-2018 IPR019489 Clp ATPase, C-terminal TSH58p_04865 d636dd006a979a7738ae8267ea406ced 499 SUPERFAMILY SSF50494 33 278 8.8E-64 T 14-10-2018 IPR009003 Peptidase S1, PA clan TSH58p_04865 d636dd006a979a7738ae8267ea406ced 499 Gene3D G3DSA:2.30.42.10 276 384 6.9E-28 T 14-10-2018 TSH58p_04865 d636dd006a979a7738ae8267ea406ced 499 Pfam PF13365 Trypsin-like peptidase domain 108 242 1.4E-33 T 14-10-2018 TSH58p_04865 d636dd006a979a7738ae8267ea406ced 499 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 35 490 2.3E-147 T 14-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 TSH58p_04865 d636dd006a979a7738ae8267ea406ced 499 Pfam PF13180 PDZ domain 281 372 1.7E-15 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_04865 d636dd006a979a7738ae8267ea406ced 499 Pfam PF13180 PDZ domain 401 491 1.9E-9 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_04865 d636dd006a979a7738ae8267ea406ced 499 SUPERFAMILY SSF50156 400 494 6.05E-14 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 TSH58p_04865 d636dd006a979a7738ae8267ea406ced 499 SUPERFAMILY SSF50156 239 364 9.73E-25 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 TSH58p_04865 d636dd006a979a7738ae8267ea406ced 499 PRINTS PR00834 HtrA/DegQ protease family signature 235 252 6.8E-55 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_04865 d636dd006a979a7738ae8267ea406ced 499 PRINTS PR00834 HtrA/DegQ protease family signature 321 333 6.8E-55 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_04865 d636dd006a979a7738ae8267ea406ced 499 PRINTS PR00834 HtrA/DegQ protease family signature 179 203 6.8E-55 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_04865 d636dd006a979a7738ae8267ea406ced 499 PRINTS PR00834 HtrA/DegQ protease family signature 138 158 6.8E-55 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_04865 d636dd006a979a7738ae8267ea406ced 499 PRINTS PR00834 HtrA/DegQ protease family signature 117 129 6.8E-55 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_04865 d636dd006a979a7738ae8267ea406ced 499 PRINTS PR00834 HtrA/DegQ protease family signature 213 230 6.8E-55 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_04865 d636dd006a979a7738ae8267ea406ced 499 Gene3D G3DSA:2.40.10.120 33 274 8.3E-81 T 14-10-2018 TSH58p_04865 d636dd006a979a7738ae8267ea406ced 499 SMART SM00228 281 363 1.5E-12 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_04865 d636dd006a979a7738ae8267ea406ced 499 SMART SM00228 400 485 3.2E-6 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_04865 d636dd006a979a7738ae8267ea406ced 499 Gene3D G3DSA:2.30.42.60 389 499 1.3E-16 T 14-10-2018 TSH58p_19020 d47acc8abc3c0fe2c326b199ea3c32e9 1050 SUPERFAMILY SSF82714 723 810 1.27E-21 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_19020 d47acc8abc3c0fe2c326b199ea3c32e9 1050 Gene3D G3DSA:3.30.70.1430 38 818 0.0 T 14-10-2018 TSH58p_19020 d47acc8abc3c0fe2c326b199ea3c32e9 1050 Gene3D G3DSA:3.30.2090.10 179 275 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_19020 d47acc8abc3c0fe2c326b199ea3c32e9 1050 SUPERFAMILY SSF82866 296 497 4.32E-49 T 14-10-2018 TSH58p_19020 d47acc8abc3c0fe2c326b199ea3c32e9 1050 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1036 0.0 T 14-10-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0006855|GO:0015562|GO:0016021 TSH58p_19020 d47acc8abc3c0fe2c326b199ea3c32e9 1050 SUPERFAMILY SSF82866 832 1027 4.45E-46 T 14-10-2018 TSH58p_19020 d47acc8abc3c0fe2c326b199ea3c32e9 1050 SUPERFAMILY SSF82714 183 272 3.66E-21 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_19020 d47acc8abc3c0fe2c326b199ea3c32e9 1050 SUPERFAMILY SSF82693 135 330 1.59E-27 T 14-10-2018 TSH58p_19020 d47acc8abc3c0fe2c326b199ea3c32e9 1050 SUPERFAMILY SSF82693 566 672 4.55E-30 T 14-10-2018 TSH58p_19020 d47acc8abc3c0fe2c326b199ea3c32e9 1050 SUPERFAMILY SSF82693 38 131 9.68E-26 T 14-10-2018 TSH58p_19020 d47acc8abc3c0fe2c326b199ea3c32e9 1050 Gene3D G3DSA:3.30.2090.10 722 810 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_19020 d47acc8abc3c0fe2c326b199ea3c32e9 1050 Gene3D G3DSA:3.30.70.1320 133 332 0.0 T 14-10-2018 TSH58p_19020 d47acc8abc3c0fe2c326b199ea3c32e9 1050 SUPERFAMILY SSF82693 673 857 1.86E-29 T 14-10-2018 TSH58p_19020 d47acc8abc3c0fe2c326b199ea3c32e9 1050 Gene3D G3DSA:1.20.1640.10 8 513 0.0 T 14-10-2018 TSH58p_19020 d47acc8abc3c0fe2c326b199ea3c32e9 1050 Pfam PF00873 AcrB/AcrD/AcrF family 1 1026 0.0 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_19020 d47acc8abc3c0fe2c326b199ea3c32e9 1050 Gene3D G3DSA:3.30.70.1430 568 669 0.0 T 14-10-2018 TSH58p_19020 d47acc8abc3c0fe2c326b199ea3c32e9 1050 Gene3D G3DSA:1.20.1640.10 514 1023 0.0 T 14-10-2018 TSH58p_19020 d47acc8abc3c0fe2c326b199ea3c32e9 1050 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 9.9E-112 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_19020 d47acc8abc3c0fe2c326b199ea3c32e9 1050 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 9.9E-112 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_19020 d47acc8abc3c0fe2c326b199ea3c32e9 1050 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 9.9E-112 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_19020 d47acc8abc3c0fe2c326b199ea3c32e9 1050 PRINTS PR00702 Acriflavin resistance protein family signature 622 636 9.9E-112 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_19020 d47acc8abc3c0fe2c326b199ea3c32e9 1050 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 9.9E-112 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_19020 d47acc8abc3c0fe2c326b199ea3c32e9 1050 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 9.9E-112 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_19020 d47acc8abc3c0fe2c326b199ea3c32e9 1050 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 9.9E-112 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_19020 d47acc8abc3c0fe2c326b199ea3c32e9 1050 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 9.9E-112 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_19020 d47acc8abc3c0fe2c326b199ea3c32e9 1050 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 9.9E-112 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_19020 d47acc8abc3c0fe2c326b199ea3c32e9 1050 Gene3D G3DSA:3.30.70.1440 670 866 0.0 T 14-10-2018 TSH58p_16075 d3fdebdbc7e61b2f75c9ad6a392d81cf 470 TIGRFAM TIGR00260 thrC: threonine synthase 69 427 1.1E-79 T 14-10-2018 IPR004450 Threonine synthase-like TSH58p_16075 d3fdebdbc7e61b2f75c9ad6a392d81cf 470 Pfam PF14821 Threonine synthase N terminus 2 80 1.2E-27 T 14-10-2018 IPR029144 Threonine synthase, N-terminal TSH58p_16075 d3fdebdbc7e61b2f75c9ad6a392d81cf 470 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 94 409 6.8E-20 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TSH58p_16075 d3fdebdbc7e61b2f75c9ad6a392d81cf 470 Gene3D G3DSA:3.90.1380.10 1 86 2.8E-29 T 14-10-2018 IPR037158 Threonine synthase, N-terminal domain superfamily TSH58p_16075 d3fdebdbc7e61b2f75c9ad6a392d81cf 470 Gene3D G3DSA:3.40.50.1100 96 431 7.7E-150 T 14-10-2018 TSH58p_16075 d3fdebdbc7e61b2f75c9ad6a392d81cf 470 SUPERFAMILY SSF53686 2 461 2.03E-161 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TSH58p_16075 d3fdebdbc7e61b2f75c9ad6a392d81cf 470 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 102 116 - T 14-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 TSH58p_16075 d3fdebdbc7e61b2f75c9ad6a392d81cf 470 Gene3D G3DSA:3.40.50.1100 108 444 7.7E-150 T 14-10-2018 TSH58p_32175 b593340d5c03d2b3d248e7f7e6200fc9 143 Gene3D G3DSA:1.10.1660.10 1 131 6.2E-35 T 14-10-2018 TSH58p_32175 b593340d5c03d2b3d248e7f7e6200fc9 143 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 7 18 8.2E-11 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_32175 b593340d5c03d2b3d248e7f7e6200fc9 143 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 42 62 8.2E-11 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_32175 b593340d5c03d2b3d248e7f7e6200fc9 143 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 18 31 8.2E-11 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_32175 b593340d5c03d2b3d248e7f7e6200fc9 143 Pfam PF09278 MerR, DNA binding 49 113 6.6E-21 T 14-10-2018 IPR015358 Transcription regulator MerR, DNA binding TSH58p_32175 b593340d5c03d2b3d248e7f7e6200fc9 143 SMART SM00422 6 75 2.5E-26 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_32175 b593340d5c03d2b3d248e7f7e6200fc9 143 Pfam PF00376 MerR family regulatory protein 7 44 4.1E-14 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_32175 b593340d5c03d2b3d248e7f7e6200fc9 143 SUPERFAMILY SSF46955 6 131 1.03E-35 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily TSH58p_21935 cfa848afb6359b0b8524c50eda4e44da 118 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 14 118 2.2E-36 T 14-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 TSH58p_21935 cfa848afb6359b0b8524c50eda4e44da 118 Pfam PF01521 Iron-sulphur cluster biosynthesis 13 114 1.6E-19 T 14-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 TSH58p_21935 cfa848afb6359b0b8524c50eda4e44da 118 Gene3D G3DSA:2.60.300.12 12 118 1.8E-36 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 TSH58p_21935 cfa848afb6359b0b8524c50eda4e44da 118 SUPERFAMILY SSF89360 11 104 4.32E-28 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 TSH58p_21935 cfa848afb6359b0b8524c50eda4e44da 118 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 99 116 - T 14-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 TSH58p_02435 b84bba5e083aea026505556811d6e20c 336 Gene3D G3DSA:1.10.10.10 79 163 7.8E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_02435 b84bba5e083aea026505556811d6e20c 336 Pfam PF13730 Helix-turn-helix domain 95 141 4.3E-11 T 14-10-2018 TSH58p_02435 b84bba5e083aea026505556811d6e20c 336 SUPERFAMILY SSF46785 100 147 2.38E-6 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_20865 924687d47f0570be5e3c99666d356c7c 306 Gene3D G3DSA:3.40.190.10 162 260 2.1E-53 T 14-10-2018 TSH58p_20865 924687d47f0570be5e3c99666d356c7c 306 SUPERFAMILY SSF46785 3 83 9.79E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_20865 924687d47f0570be5e3c99666d356c7c 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 1.1E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_20865 924687d47f0570be5e3c99666d356c7c 306 Gene3D G3DSA:3.40.190.10 101 286 2.1E-53 T 14-10-2018 TSH58p_20865 924687d47f0570be5e3c99666d356c7c 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 2.2E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_20865 924687d47f0570be5e3c99666d356c7c 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 2.2E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_20865 924687d47f0570be5e3c99666d356c7c 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 2.2E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_20865 924687d47f0570be5e3c99666d356c7c 306 Pfam PF03466 LysR substrate binding domain 91 290 6.5E-37 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_20865 924687d47f0570be5e3c99666d356c7c 306 Gene3D G3DSA:1.10.10.10 7 96 1.5E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_20865 924687d47f0570be5e3c99666d356c7c 306 SUPERFAMILY SSF53850 93 295 4.34E-35 T 14-10-2018 TSH58p_26455 7c1b1b63a474ecc0a1b201d3a15ba196 484 Gene3D G3DSA:1.25.40.10 353 450 2.5E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_26455 7c1b1b63a474ecc0a1b201d3a15ba196 484 SUPERFAMILY SSF48452 366 447 1.72E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_26455 7c1b1b63a474ecc0a1b201d3a15ba196 484 Pfam PF01739 CheR methyltransferase, SAM binding domain 80 274 2.2E-45 T 14-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal TSH58p_26455 7c1b1b63a474ecc0a1b201d3a15ba196 484 PRINTS PR00996 Glutamate methyltransferase family signature 32 45 1.8E-31 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_26455 7c1b1b63a474ecc0a1b201d3a15ba196 484 PRINTS PR00996 Glutamate methyltransferase family signature 148 164 1.8E-31 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_26455 7c1b1b63a474ecc0a1b201d3a15ba196 484 PRINTS PR00996 Glutamate methyltransferase family signature 112 132 1.8E-31 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_26455 7c1b1b63a474ecc0a1b201d3a15ba196 484 PRINTS PR00996 Glutamate methyltransferase family signature 239 262 1.8E-31 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_26455 7c1b1b63a474ecc0a1b201d3a15ba196 484 PRINTS PR00996 Glutamate methyltransferase family signature 72 84 1.8E-31 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_26455 7c1b1b63a474ecc0a1b201d3a15ba196 484 PRINTS PR00996 Glutamate methyltransferase family signature 220 234 1.8E-31 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_26455 7c1b1b63a474ecc0a1b201d3a15ba196 484 SUPERFAMILY SSF47757 8 78 2.48E-6 T 14-10-2018 TSH58p_26455 7c1b1b63a474ecc0a1b201d3a15ba196 484 SUPERFAMILY SSF53335 79 274 1.76E-44 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_26455 7c1b1b63a474ecc0a1b201d3a15ba196 484 Gene3D G3DSA:3.40.50.150 78 283 1.0E-53 T 14-10-2018 TSH58p_26455 7c1b1b63a474ecc0a1b201d3a15ba196 484 SMART SM00138 10 280 7.8E-59 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_14250 3678bb7ce1e256eb8734ba60de293eec 374 Gene3D G3DSA:2.60.60.40 29 142 4.0E-12 T 14-10-2018 TSH58p_14250 3678bb7ce1e256eb8734ba60de293eec 374 Gene3D G3DSA:2.60.60.40 161 275 1.1E-8 T 14-10-2018 TSH58p_14250 3678bb7ce1e256eb8734ba60de293eec 374 Pfam PF16841 Ca-dependent carbohydrate-binding module xylan-binding 164 255 6.8E-29 T 14-10-2018 IPR031768 Carbohydrate binding module, xylan-binding domain MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSH58p_14250 3678bb7ce1e256eb8734ba60de293eec 374 Pfam PF16841 Ca-dependent carbohydrate-binding module xylan-binding 32 123 3.4E-31 T 14-10-2018 IPR031768 Carbohydrate binding module, xylan-binding domain MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSH58p_16445 79a0d28d1611c5b4ae3d45062f4a28d1 243 Pfam PF00072 Response regulator receiver domain 6 113 1.9E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_16445 79a0d28d1611c5b4ae3d45062f4a28d1 243 Gene3D G3DSA:3.40.50.2300 1 128 5.2E-29 T 14-10-2018 TSH58p_16445 79a0d28d1611c5b4ae3d45062f4a28d1 243 SUPERFAMILY SSF46894 144 238 2.83E-16 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_16445 79a0d28d1611c5b4ae3d45062f4a28d1 243 SUPERFAMILY SSF52172 4 125 1.42E-32 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_16445 79a0d28d1611c5b4ae3d45062f4a28d1 243 SMART SM00448 4 114 1.8E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_16445 79a0d28d1611c5b4ae3d45062f4a28d1 243 Pfam PF00486 Transcriptional regulatory protein, C terminal 162 236 1.1E-14 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_16445 79a0d28d1611c5b4ae3d45062f4a28d1 243 Gene3D G3DSA:1.10.10.10 138 240 3.9E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_16445 79a0d28d1611c5b4ae3d45062f4a28d1 243 SMART SM00862 160 236 1.6E-13 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_11510 fcafe863319a3d36bcb87d883c231d18 512 Gene3D G3DSA:1.10.510.10 254 331 3.8E-5 T 14-10-2018 TSH58p_11510 fcafe863319a3d36bcb87d883c231d18 512 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 9 438 1.6E-170 T 14-10-2018 IPR010232 Probable protein kinase UbiB GO:0006744 TSH58p_11510 fcafe863319a3d36bcb87d883c231d18 512 Pfam PF03109 ABC1 family 109 227 2.4E-33 T 14-10-2018 IPR004147 UbiB domain TSH58p_11510 fcafe863319a3d36bcb87d883c231d18 512 SUPERFAMILY SSF56112 92 429 2.68E-39 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily TSH58p_21655 011201ac5cf6f8b3c334774c0302caeb 398 SUPERFAMILY SSF53474 31 397 1.88E-72 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_21655 011201ac5cf6f8b3c334774c0302caeb 398 PIRSF PIRSF000443 12 398 5.2E-107 T 14-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 TSH58p_21655 011201ac5cf6f8b3c334774c0302caeb 398 Gene3D G3DSA:3.40.50.1820 44 383 1.3E-115 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_21655 011201ac5cf6f8b3c334774c0302caeb 398 Pfam PF00561 alpha/beta hydrolase fold 137 361 4.2E-18 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_21655 011201ac5cf6f8b3c334774c0302caeb 398 Hamap MF_00296 Homoserine O-acetyltransferase [metXA]. 27 397 24.96 T 14-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 TSH58p_21655 011201ac5cf6f8b3c334774c0302caeb 398 Gene3D G3DSA:1.10.1740.110 209 315 1.3E-115 T 14-10-2018 TSH58p_28410 4dc21d2357b0d3430e3bfcde50c79de9 420 SUPERFAMILY SSF141868 244 399 6.67E-7 T 14-10-2018 IPR035919 EAL domain superfamily TSH58p_31330 3a63796d1df33f4411c654ed622bca41 857 Pfam PF00689 Cation transporting ATPase, C-terminus 675 838 3.1E-13 T 14-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 TSH58p_31330 3a63796d1df33f4411c654ed622bca41 857 Gene3D G3DSA:3.40.50.1000 326 338 1.8E-86 T 14-10-2018 IPR023214 HAD superfamily TSH58p_31330 3a63796d1df33f4411c654ed622bca41 857 Gene3D G3DSA:3.40.50.1000 500 636 2.0E-70 T 14-10-2018 IPR023214 HAD superfamily TSH58p_31330 3a63796d1df33f4411c654ed622bca41 857 Gene3D G3DSA:1.20.1110.10 637 836 2.0E-70 T 14-10-2018 TSH58p_31330 3a63796d1df33f4411c654ed622bca41 857 Gene3D G3DSA:1.20.1110.10 60 325 1.8E-86 T 14-10-2018 TSH58p_31330 3a63796d1df33f4411c654ed622bca41 857 PRINTS PR01836 Magnesium-transporting ATPase signature 259 278 6.1E-47 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 TSH58p_31330 3a63796d1df33f4411c654ed622bca41 857 PRINTS PR01836 Magnesium-transporting ATPase signature 363 376 6.1E-47 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 TSH58p_31330 3a63796d1df33f4411c654ed622bca41 857 PRINTS PR01836 Magnesium-transporting ATPase signature 751 772 6.1E-47 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 TSH58p_31330 3a63796d1df33f4411c654ed622bca41 857 PRINTS PR01836 Magnesium-transporting ATPase signature 720 736 6.1E-47 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 TSH58p_31330 3a63796d1df33f4411c654ed622bca41 857 PRINTS PR01836 Magnesium-transporting ATPase signature 242 258 6.1E-47 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 TSH58p_31330 3a63796d1df33f4411c654ed622bca41 857 PRINTS PR01836 Magnesium-transporting ATPase signature 800 821 6.1E-47 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 TSH58p_31330 3a63796d1df33f4411c654ed622bca41 857 PRINTS PR01836 Magnesium-transporting ATPase signature 650 665 6.1E-47 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 TSH58p_31330 3a63796d1df33f4411c654ed622bca41 857 PRINTS PR01836 Magnesium-transporting ATPase signature 668 679 6.1E-47 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 TSH58p_31330 3a63796d1df33f4411c654ed622bca41 857 PRINTS PR01836 Magnesium-transporting ATPase signature 700 713 6.1E-47 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 TSH58p_31330 3a63796d1df33f4411c654ed622bca41 857 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 89 358 7.9E-36 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TSH58p_31330 3a63796d1df33f4411c654ed622bca41 857 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 561 681 4.3E-27 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TSH58p_31330 3a63796d1df33f4411c654ed622bca41 857 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 17 841 2.9E-269 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 TSH58p_31330 3a63796d1df33f4411c654ed622bca41 857 Gene3D G3DSA:2.70.150.10 25 232 1.8E-86 T 14-10-2018 TSH58p_31330 3a63796d1df33f4411c654ed622bca41 857 Gene3D G3DSA:3.40.1110.10 389 499 2.0E-70 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TSH58p_31330 3a63796d1df33f4411c654ed622bca41 857 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 331 337 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 TSH58p_31330 3a63796d1df33f4411c654ed622bca41 857 SUPERFAMILY SSF56784 327 691 7.91E-38 T 14-10-2018 IPR036412 HAD-like superfamily TSH58p_31330 3a63796d1df33f4411c654ed622bca41 857 Pfam PF00702 haloacid dehalogenase-like hydrolase 325 606 3.0E-12 T 14-10-2018 TSH58p_31330 3a63796d1df33f4411c654ed622bca41 857 SUPERFAMILY SSF81653 121 228 2.75E-28 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 TSH58p_31330 3a63796d1df33f4411c654ed622bca41 857 Pfam PF00122 E1-E2 ATPase 120 307 8.5E-44 T 14-10-2018 TSH58p_31330 3a63796d1df33f4411c654ed622bca41 857 SUPERFAMILY SSF81665 11 842 1.44E-95 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 TSH58p_31330 3a63796d1df33f4411c654ed622bca41 857 Pfam PF00690 Cation transporter/ATPase, N-terminus 12 77 8.8E-16 T 14-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 TSH58p_31330 3a63796d1df33f4411c654ed622bca41 857 SMART SM00831 9 82 9.1E-22 T 14-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 Gene3D G3DSA:3.30.565.10 12 219 1.4E-74 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 Pfam PF01751 Toprim domain 436 540 2.9E-17 T 14-10-2018 IPR006171 TOPRIM domain TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 SUPERFAMILY SSF55874 15 217 1.23E-60 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 SMART SM00387 40 185 1.3E-27 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 12 657 42.541 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 579 649 5.0E-23 T 14-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 SUPERFAMILY SSF56719 411 659 3.92E-78 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 41 184 3.2E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 Gene3D G3DSA:3.40.50.670 416 662 1.0E-90 T 14-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 PRINTS PR01159 DNA gyrase subunit B signature 604 616 4.0E-15 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 PRINTS PR01159 DNA gyrase subunit B signature 392 412 4.0E-15 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 PRINTS PR01159 DNA gyrase subunit B signature 487 496 4.0E-15 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 PRINTS PR01159 DNA gyrase subunit B signature 15 25 4.0E-15 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 PRINTS PR01159 DNA gyrase subunit B signature 238 260 4.0E-15 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 PRINTS PR01159 DNA gyrase subunit B signature 378 392 4.0E-15 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 PRINTS PR00418 DNA topoisomerase II family signature 521 538 9.7E-63 T 14-10-2018 TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 PRINTS PR00418 DNA topoisomerase II family signature 44 59 9.7E-63 T 14-10-2018 TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 PRINTS PR00418 DNA topoisomerase II family signature 503 519 9.7E-63 T 14-10-2018 TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 PRINTS PR00418 DNA topoisomerase II family signature 79 92 9.7E-63 T 14-10-2018 TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 PRINTS PR00418 DNA topoisomerase II family signature 437 451 9.7E-63 T 14-10-2018 TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 PRINTS PR00418 DNA topoisomerase II family signature 583 599 9.7E-63 T 14-10-2018 TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 PRINTS PR00418 DNA topoisomerase II family signature 288 301 9.7E-63 T 14-10-2018 TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 PRINTS PR00418 DNA topoisomerase II family signature 541 553 9.7E-63 T 14-10-2018 TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 PRINTS PR00418 DNA topoisomerase II family signature 123 137 9.7E-63 T 14-10-2018 TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 SMART SM00433 44 653 6.4E-280 T 14-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 SUPERFAMILY SSF54211 239 409 5.69E-41 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 Gene3D G3DSA:3.30.230.10 239 413 5.3E-46 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 ProSitePatterns PS00177 DNA topoisomerase II signature. 439 447 - T 14-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 TIGRFAM TIGR01055 parE_Gneg: DNA topoisomerase IV, B subunit 13 652 6.1E-238 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TSH58p_29860 a21d527ebe4eb61d1d9404b1b82ed301 662 Pfam PF00204 DNA gyrase B 239 408 1.1E-40 T 14-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TSH58p_03310 5f33e22c5c71850b475af2f64ae4cbe3 474 Pfam PF13183 4Fe-4S dicluster domain 310 376 1.1E-11 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_03310 5f33e22c5c71850b475af2f64ae4cbe3 474 Pfam PF02589 LUD domain 68 293 2.0E-56 T 14-10-2018 IPR003741 LUD domain TSH58p_03310 5f33e22c5c71850b475af2f64ae4cbe3 474 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 312 323 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_03310 5f33e22c5c71850b475af2f64ae4cbe3 474 SUPERFAMILY SSF46548 310 390 1.15E-17 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSH58p_03310 5f33e22c5c71850b475af2f64ae4cbe3 474 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 362 373 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_03310 5f33e22c5c71850b475af2f64ae4cbe3 474 SUPERFAMILY SSF100950 63 294 7.95E-41 T 14-10-2018 IPR037171 NagB/RpiA transferase-like TSH58p_03310 5f33e22c5c71850b475af2f64ae4cbe3 474 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 16 455 8.8E-147 T 14-10-2018 IPR004452 4Fe-4S binding protein GO:0019516 TSH58p_03310 5f33e22c5c71850b475af2f64ae4cbe3 474 Gene3D G3DSA:3.40.50.10420 124 281 6.3E-16 T 14-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily TSH58p_03310 5f33e22c5c71850b475af2f64ae4cbe3 474 Pfam PF11870 Domain of unknown function (DUF3390) 384 470 5.1E-24 T 14-10-2018 IPR024569 4Fe-4S binding protein, C-terminal TSH58p_19940 b58b45bc996e2d26d65bd2003bcd5d13 806 Gene3D G3DSA:1.10.287.130 559 646 1.1E-18 T 14-10-2018 TSH58p_19940 b58b45bc996e2d26d65bd2003bcd5d13 806 SUPERFAMILY SSF47384 580 648 1.94E-9 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_19940 b58b45bc996e2d26d65bd2003bcd5d13 806 Pfam PF00512 His Kinase A (phospho-acceptor) domain 583 648 1.4E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_19940 b58b45bc996e2d26d65bd2003bcd5d13 806 SMART SM00304 361 413 2.1E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_19940 b58b45bc996e2d26d65bd2003bcd5d13 806 Pfam PF08448 PAS fold 421 530 1.4E-6 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_19940 b58b45bc996e2d26d65bd2003bcd5d13 806 Gene3D G3DSA:3.30.565.10 653 806 1.0E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_19940 b58b45bc996e2d26d65bd2003bcd5d13 806 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 699 803 5.8E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_19940 b58b45bc996e2d26d65bd2003bcd5d13 806 PRINTS PR00344 Bacterial sensor protein C-terminal signature 736 750 8.1E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_19940 b58b45bc996e2d26d65bd2003bcd5d13 806 PRINTS PR00344 Bacterial sensor protein C-terminal signature 791 804 8.1E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_19940 b58b45bc996e2d26d65bd2003bcd5d13 806 PRINTS PR00344 Bacterial sensor protein C-terminal signature 754 764 8.1E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_19940 b58b45bc996e2d26d65bd2003bcd5d13 806 PRINTS PR00344 Bacterial sensor protein C-terminal signature 767 785 8.1E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_19940 b58b45bc996e2d26d65bd2003bcd5d13 806 Pfam PF00672 HAMP domain 361 408 1.2E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_19940 b58b45bc996e2d26d65bd2003bcd5d13 806 SMART SM00388 583 651 3.9E-5 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_19940 b58b45bc996e2d26d65bd2003bcd5d13 806 Gene3D G3DSA:1.20.58.920 60 191 1.8E-8 T 14-10-2018 IPR038188 TorS, sensor domain superfamily TSH58p_19940 b58b45bc996e2d26d65bd2003bcd5d13 806 SMART SM00086 489 529 0.0012 T 14-10-2018 IPR001610 PAC motif TSH58p_19940 b58b45bc996e2d26d65bd2003bcd5d13 806 Gene3D G3DSA:1.20.1480.50 319 418 4.7E-10 T 14-10-2018 TSH58p_19940 b58b45bc996e2d26d65bd2003bcd5d13 806 SUPERFAMILY SSF55785 426 538 1.19E-12 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_19940 b58b45bc996e2d26d65bd2003bcd5d13 806 SMART SM00387 697 806 1.5E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_19940 b58b45bc996e2d26d65bd2003bcd5d13 806 PIRSF PIRSF037119 14 806 7.1E-124 T 14-10-2018 IPR017116 Signal transduction histidine kinase, PgtB TSH58p_19940 b58b45bc996e2d26d65bd2003bcd5d13 806 SUPERFAMILY SSF158472 361 407 1.44E-6 T 14-10-2018 TSH58p_19940 b58b45bc996e2d26d65bd2003bcd5d13 806 Gene3D G3DSA:3.30.450.20 424 537 1.3E-12 T 14-10-2018 TSH58p_19940 b58b45bc996e2d26d65bd2003bcd5d13 806 SUPERFAMILY SSF55874 640 803 9.69E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_05715 796417ad63358f75663088949c9a161e 262 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 15 49 3.8E-8 T 14-10-2018 IPR001451 Hexapeptide repeat TSH58p_05715 796417ad63358f75663088949c9a161e 262 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 106 140 2.0E-5 T 14-10-2018 IPR001451 Hexapeptide repeat TSH58p_05715 796417ad63358f75663088949c9a161e 262 PIRSF PIRSF000456 1 261 1.5E-107 T 14-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 TSH58p_05715 796417ad63358f75663088949c9a161e 262 SUPERFAMILY SSF51161 3 251 1.23E-74 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily TSH58p_05715 796417ad63358f75663088949c9a161e 262 Gene3D G3DSA:1.20.1180.10 195 261 7.0E-14 T 14-10-2018 IPR037157 UDP-N-acetylglucosamine O-acyltransferase, C-terminal domain superfamily KEGG: 00540+2.3.1.129 TSH58p_05715 796417ad63358f75663088949c9a161e 262 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 2 258 44.372 T 14-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 TSH58p_05715 796417ad63358f75663088949c9a161e 262 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 17 45 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 TSH58p_05715 796417ad63358f75663088949c9a161e 262 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 5 254 4.3E-105 T 14-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 TSH58p_05715 796417ad63358f75663088949c9a161e 262 Gene3D G3DSA:2.160.10.10 1 192 2.0E-52 T 14-10-2018 TSH58p_05715 796417ad63358f75663088949c9a161e 262 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 132 160 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 TSH58p_05715 796417ad63358f75663088949c9a161e 262 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 177 254 1.3E-22 T 14-10-2018 IPR029098 UDP N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00540+2.3.1.129 TSH58p_23550 5969a9e774903aa41d0614ed94214536 717 Gene3D G3DSA:3.20.20.240 1 563 1.6E-249 T 14-10-2018 TSH58p_23550 5969a9e774903aa41d0614ed94214536 717 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 31 551 2.2E-275 T 14-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TSH58p_23550 5969a9e774903aa41d0614ed94214536 717 Pfam PF02310 B12 binding domain 587 698 8.4E-14 T 14-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 TSH58p_23550 5969a9e774903aa41d0614ed94214536 717 SUPERFAMILY SSF51703 2 547 1.12E-226 T 14-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TSH58p_23550 5969a9e774903aa41d0614ed94214536 717 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 584 714 7.9E-61 T 14-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TSH58p_23550 5969a9e774903aa41d0614ed94214536 717 SUPERFAMILY SSF52242 551 712 8.24E-60 T 14-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 TSH58p_23550 5969a9e774903aa41d0614ed94214536 717 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 374 399 - T 14-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TSH58p_23550 5969a9e774903aa41d0614ed94214536 717 Gene3D G3DSA:3.40.50.280 569 717 3.2E-51 T 14-10-2018 TSH58p_23550 5969a9e774903aa41d0614ed94214536 717 Pfam PF01642 Methylmalonyl-CoA mutase 32 544 2.2E-243 T 14-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TSH58p_03130 c6b6b5e5f33252647afc56d98260bea7 423 Pfam PF01547 Bacterial extracellular solute-binding protein 45 321 5.3E-26 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSH58p_03130 c6b6b5e5f33252647afc56d98260bea7 423 Gene3D G3DSA:3.40.190.10 137 409 2.5E-79 T 14-10-2018 TSH58p_03130 c6b6b5e5f33252647afc56d98260bea7 423 Gene3D G3DSA:3.40.190.10 52 369 2.5E-79 T 14-10-2018 TSH58p_03130 c6b6b5e5f33252647afc56d98260bea7 423 SUPERFAMILY SSF53850 25 397 1.89E-68 T 14-10-2018 TSH58p_14130 2f87f88d7f78bf904024e704af6ad334 490 SMART SM00388 102 185 8.3E-7 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_14130 2f87f88d7f78bf904024e704af6ad334 490 Gene3D G3DSA:3.30.565.10 196 342 6.2E-16 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_14130 2f87f88d7f78bf904024e704af6ad334 490 Pfam PF00512 His Kinase A (phospho-acceptor) domain 104 185 8.1E-7 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_14130 2f87f88d7f78bf904024e704af6ad334 490 SUPERFAMILY SSF47384 104 185 1.14E-7 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_14130 2f87f88d7f78bf904024e704af6ad334 490 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 230 335 2.6E-5 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_14130 2f87f88d7f78bf904024e704af6ad334 490 Gene3D G3DSA:3.40.50.2300 360 490 4.2E-21 T 14-10-2018 TSH58p_14130 2f87f88d7f78bf904024e704af6ad334 490 SUPERFAMILY SSF52172 363 488 1.25E-23 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_14130 2f87f88d7f78bf904024e704af6ad334 490 SMART SM00448 365 479 2.5E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_14130 2f87f88d7f78bf904024e704af6ad334 490 Gene3D G3DSA:1.10.287.130 100 187 6.1E-7 T 14-10-2018 TSH58p_14130 2f87f88d7f78bf904024e704af6ad334 490 SUPERFAMILY SSF55874 198 340 2.84E-18 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_14130 2f87f88d7f78bf904024e704af6ad334 490 Pfam PF00072 Response regulator receiver domain 367 479 4.0E-14 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_32320 64a47dfb613130f2e11e64f9864f624a 259 SMART SM00062 29 256 2.1E-55 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_32320 64a47dfb613130f2e11e64f9864f624a 259 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 30 253 6.1E-58 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_32320 64a47dfb613130f2e11e64f9864f624a 259 SUPERFAMILY SSF53850 1 253 5.49E-61 T 14-10-2018 TSH58p_32320 64a47dfb613130f2e11e64f9864f624a 259 Gene3D G3DSA:3.40.190.10 32 252 1.2E-70 T 14-10-2018 TSH58p_32320 64a47dfb613130f2e11e64f9864f624a 259 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 52 65 - T 14-10-2018 IPR018313 Solute-binding protein family 3, conserved site TSH58p_32320 64a47dfb613130f2e11e64f9864f624a 259 Gene3D G3DSA:3.40.190.10 115 212 1.2E-70 T 14-10-2018 TSH58p_15335 c10f800a9c702554f33260182f1d24b9 508 Pfam PF10119 Predicted methyltransferase regulatory domain 219 301 3.3E-30 T 14-10-2018 IPR018773 Methyltransferase regulatory domain, predicted TSH58p_15335 c10f800a9c702554f33260182f1d24b9 508 Pfam PF13649 Methyltransferase domain 50 146 4.4E-10 T 14-10-2018 TSH58p_15335 c10f800a9c702554f33260182f1d24b9 508 SUPERFAMILY SSF53335 41 178 1.06E-21 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_15335 c10f800a9c702554f33260182f1d24b9 508 Gene3D G3DSA:3.40.50.150 32 209 4.2E-17 T 14-10-2018 TSH58p_15165 ad10b4416b1bdb93971fcbeaa39955af 236 SUPERFAMILY SSF50447 1 213 4.15E-83 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSH58p_15165 ad10b4416b1bdb93971fcbeaa39955af 236 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 208 37.092 T 14-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_15165 ad10b4416b1bdb93971fcbeaa39955af 236 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 205 1.8E-87 T 14-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_15165 ad10b4416b1bdb93971fcbeaa39955af 236 Gene3D G3DSA:2.40.30.10 130 211 9.7E-16 T 14-10-2018 TSH58p_15165 ad10b4416b1bdb93971fcbeaa39955af 236 ProSitePatterns PS00474 Ribosomal protein L3 signature. 102 125 - T 14-10-2018 IPR019926 Ribosomal protein L3, conserved site TSH58p_15165 ad10b4416b1bdb93971fcbeaa39955af 236 Pfam PF00297 Ribosomal protein L3 88 183 8.2E-16 T 14-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15165 ad10b4416b1bdb93971fcbeaa39955af 236 Gene3D G3DSA:2.40.50.620 32 97 2.8E-28 T 14-10-2018 TSH58p_28420 2df6ec8308b09e67a184c851204b39b1 609 Pfam PF00152 tRNA synthetases class II (D, K and N) 122 567 1.1E-91 T 14-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_28420 2df6ec8308b09e67a184c851204b39b1 609 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 5 592 3.6E-184 T 14-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 TSH58p_28420 2df6ec8308b09e67a184c851204b39b1 609 SUPERFAMILY SSF55681 114 593 5.57E-95 T 14-10-2018 TSH58p_28420 2df6ec8308b09e67a184c851204b39b1 609 Gene3D G3DSA:3.30.930.10 120 592 1.1E-162 T 14-10-2018 TSH58p_28420 2df6ec8308b09e67a184c851204b39b1 609 Pfam PF02938 GAD domain 322 409 5.7E-17 T 14-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 TSH58p_28420 2df6ec8308b09e67a184c851204b39b1 609 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 4 594 30.503 T 14-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 TSH58p_28420 2df6ec8308b09e67a184c851204b39b1 609 SUPERFAMILY SSF50249 4 107 2.86E-29 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_28420 2df6ec8308b09e67a184c851204b39b1 609 Gene3D G3DSA:2.40.50.140 1 105 6.7E-35 T 14-10-2018 TSH58p_28420 2df6ec8308b09e67a184c851204b39b1 609 Pfam PF01336 OB-fold nucleic acid binding domain 21 100 5.9E-14 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TSH58p_28420 2df6ec8308b09e67a184c851204b39b1 609 Gene3D G3DSA:3.30.1360.30 284 429 1.1E-162 T 14-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 TSH58p_28420 2df6ec8308b09e67a184c851204b39b1 609 PRINTS PR01042 Aspartyl-tRNA synthetase signature 528 542 9.3E-21 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_28420 2df6ec8308b09e67a184c851204b39b1 609 PRINTS PR01042 Aspartyl-tRNA synthetase signature 194 206 9.3E-21 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_28420 2df6ec8308b09e67a184c851204b39b1 609 PRINTS PR01042 Aspartyl-tRNA synthetase signature 484 500 9.3E-21 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_28420 2df6ec8308b09e67a184c851204b39b1 609 PRINTS PR01042 Aspartyl-tRNA synthetase signature 211 224 9.3E-21 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_28420 2df6ec8308b09e67a184c851204b39b1 609 SUPERFAMILY SSF55261 301 429 1.11E-33 T 14-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 TSH58p_07645 a0d8be65e9cfe41b5261561e1476d614 519 Pfam PF11844 Domain of unknown function (DUF3364) 6 60 7.6E-25 T 14-10-2018 IPR024564 Nitrogenase molybdenum-iron protein beta chain, N-terminal KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 TSH58p_07645 a0d8be65e9cfe41b5261561e1476d614 519 Gene3D G3DSA:1.20.89.10 324 519 1.3E-87 T 14-10-2018 TSH58p_07645 a0d8be65e9cfe41b5261561e1476d614 519 Gene3D G3DSA:3.40.50.1980 368 480 1.3E-87 T 14-10-2018 TSH58p_07645 a0d8be65e9cfe41b5261561e1476d614 519 TIGRFAM TIGR01286 nifK: nitrogenase molybdenum-iron protein beta chain 6 519 2.3E-254 T 14-10-2018 IPR005976 Nitrogenase molybdenum-iron protein beta chain GO:0009399|GO:0016163|GO:0016612|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 TSH58p_07645 a0d8be65e9cfe41b5261561e1476d614 519 Gene3D G3DSA:3.40.50.1980 221 323 7.4E-31 T 14-10-2018 TSH58p_07645 a0d8be65e9cfe41b5261561e1476d614 519 ProSitePatterns PS00090 Nitrogenases component 1 alpha and beta subunits signature 2. 155 169 - T 14-10-2018 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 TSH58p_07645 a0d8be65e9cfe41b5261561e1476d614 519 ProSitePatterns PS00699 Nitrogenases component 1 alpha and beta subunits signature 1. 92 99 - T 14-10-2018 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 TSH58p_07645 a0d8be65e9cfe41b5261561e1476d614 519 Gene3D G3DSA:3.40.50.1980 74 215 1.6E-42 T 14-10-2018 TSH58p_07645 a0d8be65e9cfe41b5261561e1476d614 519 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 74 497 4.2E-114 T 14-10-2018 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 TSH58p_07645 a0d8be65e9cfe41b5261561e1476d614 519 SUPERFAMILY SSF53807 7 518 8.18E-170 T 14-10-2018 TSH58p_05490 c5379b875daa0f5c3c000b535629e026 453 Gene3D G3DSA:2.40.50.100 77 133 5.1E-9 T 14-10-2018 TSH58p_05490 c5379b875daa0f5c3c000b535629e026 453 Pfam PF13437 HlyD family secretion protein 305 415 3.4E-12 T 14-10-2018 TSH58p_05490 c5379b875daa0f5c3c000b535629e026 453 Gene3D G3DSA:1.10.287.470 243 304 7.7E-12 T 14-10-2018 TSH58p_05490 c5379b875daa0f5c3c000b535629e026 453 Pfam PF13533 Biotin-lipoyl like 83 114 5.2E-8 T 14-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain TSH58p_05490 c5379b875daa0f5c3c000b535629e026 453 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 417 432 3.9E-40 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_05490 c5379b875daa0f5c3c000b535629e026 453 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 350 374 3.9E-40 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_05490 c5379b875daa0f5c3c000b535629e026 453 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 432 452 3.9E-40 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_05490 c5379b875daa0f5c3c000b535629e026 453 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 41 64 3.9E-40 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_05490 c5379b875daa0f5c3c000b535629e026 453 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 83 103 3.9E-40 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_05490 c5379b875daa0f5c3c000b535629e026 453 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 317 338 3.9E-40 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_05490 c5379b875daa0f5c3c000b535629e026 453 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 374 397 3.9E-40 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_05490 c5379b875daa0f5c3c000b535629e026 453 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 35 450 1.3E-86 T 14-10-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 TSH58p_05490 c5379b875daa0f5c3c000b535629e026 453 Gene3D G3DSA:2.40.30.170 342 430 7.7E-12 T 14-10-2018 TSH58p_05490 c5379b875daa0f5c3c000b535629e026 453 Gene3D G3DSA:2.40.50.100 305 341 7.7E-12 T 14-10-2018 TSH58p_27535 68ac8137809257935bb2757e6b0acad9 243 Gene3D G3DSA:1.10.10.10 119 228 3.9E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_27535 68ac8137809257935bb2757e6b0acad9 243 SMART SM00862 145 221 7.3E-19 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_27535 68ac8137809257935bb2757e6b0acad9 243 Pfam PF00072 Response regulator receiver domain 3 113 5.3E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_27535 68ac8137809257935bb2757e6b0acad9 243 Gene3D G3DSA:3.40.50.2300 1 118 4.8E-37 T 14-10-2018 TSH58p_27535 68ac8137809257935bb2757e6b0acad9 243 SMART SM00448 1 112 6.6E-40 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_27535 68ac8137809257935bb2757e6b0acad9 243 SUPERFAMILY SSF52172 1 173 3.27E-40 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_27535 68ac8137809257935bb2757e6b0acad9 243 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 5.7E-20 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_12180 90c81b6d4b5cbf9c6356471069bc030b 117 Gene3D G3DSA:3.30.2010.20 1 113 2.1E-31 T 14-10-2018 IPR038555 Zincin-like metallopeptidase superfamily TSH58p_12180 90c81b6d4b5cbf9c6356471069bc030b 117 Pfam PF06262 Zincin-like metallopeptidase 18 113 4.1E-36 T 14-10-2018 IPR010428 Zincin-like metallopeptidase TSH58p_12180 90c81b6d4b5cbf9c6356471069bc030b 117 SUPERFAMILY SSF55486 1 113 4.67E-33 T 14-10-2018 TSH58p_09115 2ef36741ad600ce79d99cc28afb9ab85 356 Gene3D G3DSA:3.40.190.10 39 346 1.5E-111 T 14-10-2018 TSH58p_09115 2ef36741ad600ce79d99cc28afb9ab85 356 SUPERFAMILY SSF53850 60 264 2.05E-38 T 14-10-2018 TSH58p_09115 2ef36741ad600ce79d99cc28afb9ab85 356 Gene3D G3DSA:3.40.190.10 123 224 1.5E-111 T 14-10-2018 TSH58p_09115 2ef36741ad600ce79d99cc28afb9ab85 356 Pfam PF09084 NMT1/THI5 like 66 256 1.6E-15 T 14-10-2018 IPR015168 SsuA/THI5-like TSH58p_08640 6c81ff58fa9d862ea505fd852a5e67ee 158 Gene3D G3DSA:1.20.1260.10 1 158 7.3E-66 T 14-10-2018 IPR012347 Ferritin-like TSH58p_08640 6c81ff58fa9d862ea505fd852a5e67ee 158 SUPERFAMILY SSF47240 2 153 2.5E-50 T 14-10-2018 IPR009078 Ferritin-like superfamily TSH58p_08640 6c81ff58fa9d862ea505fd852a5e67ee 158 PIRSF PIRSF002560 1 157 3.2E-68 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSH58p_08640 6c81ff58fa9d862ea505fd852a5e67ee 158 Pfam PF00210 Ferritin-like domain 9 144 6.8E-39 T 14-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 TSH58p_08640 6c81ff58fa9d862ea505fd852a5e67ee 158 PRINTS PR00601 Bacterioferritin signature 107 127 4.3E-65 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSH58p_08640 6c81ff58fa9d862ea505fd852a5e67ee 158 PRINTS PR00601 Bacterioferritin signature 3 22 4.3E-65 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSH58p_08640 6c81ff58fa9d862ea505fd852a5e67ee 158 PRINTS PR00601 Bacterioferritin signature 128 149 4.3E-65 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSH58p_08640 6c81ff58fa9d862ea505fd852a5e67ee 158 PRINTS PR00601 Bacterioferritin signature 65 85 4.3E-65 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSH58p_08640 6c81ff58fa9d862ea505fd852a5e67ee 158 PRINTS PR00601 Bacterioferritin signature 86 106 4.3E-65 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSH58p_08640 6c81ff58fa9d862ea505fd852a5e67ee 158 PRINTS PR00601 Bacterioferritin signature 23 43 4.3E-65 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSH58p_08640 6c81ff58fa9d862ea505fd852a5e67ee 158 PRINTS PR00601 Bacterioferritin signature 44 64 4.3E-65 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSH58p_08640 6c81ff58fa9d862ea505fd852a5e67ee 158 TIGRFAM TIGR00754 bfr: bacterioferritin 2 155 6.7E-71 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSH58p_07090 b2538e85af97a00cbd95059c9a96f3d6 248 SUPERFAMILY SSF53335 6 244 9.73E-43 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_07090 b2538e85af97a00cbd95059c9a96f3d6 248 PIRSF PIRSF034653 1 248 2.1E-114 T 14-10-2018 IPR017031 Predicted S-adenosyl-L-methionine dependent methyltransferase, YjhP-type TSH58p_07090 b2538e85af97a00cbd95059c9a96f3d6 248 Gene3D G3DSA:3.40.50.150 1 248 1.9E-97 T 14-10-2018 TSH58p_07090 b2538e85af97a00cbd95059c9a96f3d6 248 Pfam PF13847 Methyltransferase domain 35 159 6.3E-9 T 14-10-2018 IPR025714 Methyltransferase domain TSH58p_07890 9975225fa3af906cbb337dcf9df6c662 246 Gene3D G3DSA:3.40.50.300 42 246 3.3E-69 T 14-10-2018 TSH58p_07890 9975225fa3af906cbb337dcf9df6c662 246 Pfam PF02562 PhoH-like protein 44 244 4.7E-81 T 14-10-2018 IPR003714 PhoH-like protein GO:0005524 TSH58p_07890 9975225fa3af906cbb337dcf9df6c662 246 SUPERFAMILY SSF52540 44 223 6.27E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_18005 302584051116ec8b464d6fc47de87e01 309 Gene3D G3DSA:1.10.10.10 3 84 7.7E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_18005 302584051116ec8b464d6fc47de87e01 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 4.7E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_18005 302584051116ec8b464d6fc47de87e01 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 4.7E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_18005 302584051116ec8b464d6fc47de87e01 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 4.7E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_18005 302584051116ec8b464d6fc47de87e01 309 Gene3D G3DSA:3.40.190.290 91 286 1.2E-32 T 14-10-2018 TSH58p_18005 302584051116ec8b464d6fc47de87e01 309 SUPERFAMILY SSF46785 1 111 5.44E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_18005 302584051116ec8b464d6fc47de87e01 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 4.3E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_18005 302584051116ec8b464d6fc47de87e01 309 Pfam PF03466 LysR substrate binding domain 89 285 1.5E-27 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_18005 302584051116ec8b464d6fc47de87e01 309 SUPERFAMILY SSF53850 90 291 1.74E-31 T 14-10-2018 TSH58p_17915 27ce0a4c2d19b5227eee0cd6f0ed9080 379 Gene3D G3DSA:3.30.565.10 248 379 1.3E-27 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_17915 27ce0a4c2d19b5227eee0cd6f0ed9080 379 Pfam PF13426 PAS domain 50 144 4.0E-12 T 14-10-2018 IPR000014 PAS domain TSH58p_17915 27ce0a4c2d19b5227eee0cd6f0ed9080 379 Pfam PF07568 Histidine kinase 191 264 5.2E-17 T 14-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain TSH58p_17915 27ce0a4c2d19b5227eee0cd6f0ed9080 379 Pfam PF13581 Histidine kinase-like ATPase domain 280 339 4.1E-7 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_17915 27ce0a4c2d19b5227eee0cd6f0ed9080 379 SMART SM00387 287 379 9.8E-8 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_17915 27ce0a4c2d19b5227eee0cd6f0ed9080 379 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 52 152 7.9E-13 T 14-10-2018 IPR000014 PAS domain TSH58p_17915 27ce0a4c2d19b5227eee0cd6f0ed9080 379 Gene3D G3DSA:3.30.450.20 42 242 7.4E-37 T 14-10-2018 TSH58p_17915 27ce0a4c2d19b5227eee0cd6f0ed9080 379 SMART SM00911 191 280 9.5E-4 T 14-10-2018 IPR011102 Signal transduction histidine kinase, HWE region GO:0004673 TSH58p_17915 27ce0a4c2d19b5227eee0cd6f0ed9080 379 SUPERFAMILY SSF55874 251 378 1.57E-18 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_17915 27ce0a4c2d19b5227eee0cd6f0ed9080 379 SUPERFAMILY SSF55785 40 146 4.71E-20 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_22975 7894c0251240a792bceba09a34ebf388 248 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 247 1.8E-6 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSH58p_22975 7894c0251240a792bceba09a34ebf388 248 Gene3D G3DSA:3.40.50.300 4 248 5.1E-58 T 14-10-2018 TSH58p_22975 7894c0251240a792bceba09a34ebf388 248 Pfam PF00005 ABC transporter 25 178 2.1E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_22975 7894c0251240a792bceba09a34ebf388 248 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 8 248 3.1E-113 T 14-10-2018 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD TSH58p_22975 7894c0251240a792bceba09a34ebf388 248 SUPERFAMILY SSF52540 7 246 4.15E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_14755 e0dd62007caa9e79f111e4c3d31c2a72 219 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 76 146 4.5E-9 T 14-10-2018 TSH58p_14755 e0dd62007caa9e79f111e4c3d31c2a72 219 SUPERFAMILY SSF53335 44 184 1.3E-22 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_14755 e0dd62007caa9e79f111e4c3d31c2a72 219 Gene3D G3DSA:3.40.50.150 39 213 1.4E-20 T 14-10-2018 TSH58p_11520 26238094f2c7b74d19f2dd783cb68622 634 Pfam PF13432 Tetratricopeptide repeat 284 331 0.0012 T 14-10-2018 TSH58p_11520 26238094f2c7b74d19f2dd783cb68622 634 Gene3D G3DSA:1.25.40.10 3 182 2.5E-25 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_11520 26238094f2c7b74d19f2dd783cb68622 634 Gene3D G3DSA:1.25.40.10 183 340 1.4E-27 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_11520 26238094f2c7b74d19f2dd783cb68622 634 SUPERFAMILY SSF48452 186 333 5.52E-23 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_11520 26238094f2c7b74d19f2dd783cb68622 634 SMART SM00028 106 139 120.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_11520 26238094f2c7b74d19f2dd783cb68622 634 SMART SM00028 202 235 14.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_11520 26238094f2c7b74d19f2dd783cb68622 634 SMART SM00028 72 105 30.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_11520 26238094f2c7b74d19f2dd783cb68622 634 SMART SM00028 140 173 35.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_11520 26238094f2c7b74d19f2dd783cb68622 634 SMART SM00028 270 303 91.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_11520 26238094f2c7b74d19f2dd783cb68622 634 SMART SM00028 236 269 7.8E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_11520 26238094f2c7b74d19f2dd783cb68622 634 SUPERFAMILY SSF53756 357 627 1.26E-17 T 14-10-2018 TSH58p_11520 26238094f2c7b74d19f2dd783cb68622 634 Pfam PF14559 Tetratricopeptide repeat 215 272 4.7E-6 T 14-10-2018 TSH58p_11520 26238094f2c7b74d19f2dd783cb68622 634 Gene3D G3DSA:3.40.50.2000 484 604 1.6E-8 T 14-10-2018 TSH58p_11520 26238094f2c7b74d19f2dd783cb68622 634 SUPERFAMILY SSF48452 8 174 2.9E-23 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_11520 26238094f2c7b74d19f2dd783cb68622 634 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 495 578 3.4E-5 T 14-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 TSH58p_20155 5ba6b39328c4180b9b86081d953f1818 836 TIGRFAM TIGR01706 NAPA: periplasmic nitrate reductase, large subunit 3 835 0.0 T 14-10-2018 IPR010051 Periplasmic nitrate reductase, large subunit GO:0008940|GO:0030151|GO:0042597|GO:0055114 KEGG: 00910+1.9.6.1|MetaCyc: PWY-5674 TSH58p_20155 5ba6b39328c4180b9b86081d953f1818 836 SUPERFAMILY SSF50692 696 834 2.68E-42 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TSH58p_20155 5ba6b39328c4180b9b86081d953f1818 836 Gene3D G3DSA:2.40.40.20 711 835 1.0E-47 T 14-10-2018 TSH58p_20155 5ba6b39328c4180b9b86081d953f1818 836 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 47 98 2.2E-15 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_20155 5ba6b39328c4180b9b86081d953f1818 836 SMART SM00926 45 99 1.1E-11 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_20155 5ba6b39328c4180b9b86081d953f1818 836 Hamap MF_01630 Periplasmic nitrate reductase [napA]. 1 835 32.506 T 14-10-2018 IPR010051 Periplasmic nitrate reductase, large subunit GO:0008940|GO:0030151|GO:0042597|GO:0055114 KEGG: 00910+1.9.6.1|MetaCyc: PWY-5674 TSH58p_20155 5ba6b39328c4180b9b86081d953f1818 836 Gene3D G3DSA:3.40.50.740 102 630 0.0 T 14-10-2018 TSH58p_20155 5ba6b39328c4180b9b86081d953f1818 836 Pfam PF01568 Molydopterin dinucleotide binding domain 721 829 1.9E-25 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TSH58p_20155 5ba6b39328c4180b9b86081d953f1818 836 SUPERFAMILY SSF53706 44 707 7.33E-204 T 14-10-2018 TSH58p_20155 5ba6b39328c4180b9b86081d953f1818 836 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 50 67 - T 14-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 TSH58p_20155 5ba6b39328c4180b9b86081d953f1818 836 Pfam PF00384 Molybdopterin oxidoreductase 102 575 5.9E-95 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_20155 5ba6b39328c4180b9b86081d953f1818 836 Gene3D G3DSA:3.30.200.210 46 673 0.0 T 14-10-2018 TSH58p_20155 5ba6b39328c4180b9b86081d953f1818 836 Gene3D G3DSA:3.40.228.10 181 710 0.0 T 14-10-2018 TSH58p_27330 f328ee48b1570067e88401bfb39ec276 264 SUPERFAMILY SSF46689 182 214 7.17E-5 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_27330 f328ee48b1570067e88401bfb39ec276 264 Pfam PF07883 Cupin domain 65 110 3.8E-9 T 14-10-2018 IPR013096 Cupin 2, conserved barrel TSH58p_27330 f328ee48b1570067e88401bfb39ec276 264 Gene3D G3DSA:1.10.10.60 159 223 7.4E-9 T 14-10-2018 TSH58p_27330 f328ee48b1570067e88401bfb39ec276 264 SMART SM00342 179 262 2.3E-24 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TSH58p_27330 f328ee48b1570067e88401bfb39ec276 264 Gene3D G3DSA:1.10.10.60 224 264 2.8E-12 T 14-10-2018 TSH58p_27330 f328ee48b1570067e88401bfb39ec276 264 Gene3D G3DSA:2.60.120.10 49 131 2.5E-12 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_27330 f328ee48b1570067e88401bfb39ec276 264 Pfam PF12833 Helix-turn-helix domain 187 263 5.0E-23 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TSH58p_27330 f328ee48b1570067e88401bfb39ec276 264 SUPERFAMILY SSF46689 217 263 4.08E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_27330 f328ee48b1570067e88401bfb39ec276 264 SUPERFAMILY SSF51182 63 127 8.9E-15 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_27330 f328ee48b1570067e88401bfb39ec276 264 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 217 258 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 TSH58p_13815 7dac855d0d701c70d1f34e7326afe20a 669 Gene3D G3DSA:1.10.287.950 378 663 5.4E-57 T 14-10-2018 TSH58p_13815 7dac855d0d701c70d1f34e7326afe20a 669 SUPERFAMILY SSF58104 348 662 3.79E-65 T 14-10-2018 TSH58p_13815 7dac855d0d701c70d1f34e7326afe20a 669 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 430 459 1.2E-22 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_13815 7dac855d0d701c70d1f34e7326afe20a 669 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 536 565 1.2E-22 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_13815 7dac855d0d701c70d1f34e7326afe20a 669 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 179 194 1.2E-22 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_13815 7dac855d0d701c70d1f34e7326afe20a 669 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 507 534 1.2E-22 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_13815 7dac855d0d701c70d1f34e7326afe20a 669 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 584 613 1.2E-22 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_13815 7dac855d0d701c70d1f34e7326afe20a 669 Pfam PF12729 Four helix bundle sensory module for signal transduction 7 143 1.1E-6 T 14-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain TSH58p_13815 7dac855d0d701c70d1f34e7326afe20a 669 SMART SM00283 409 663 5.3E-51 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_13815 7dac855d0d701c70d1f34e7326afe20a 669 Pfam PF00672 HAMP domain 321 368 4.6E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_13815 7dac855d0d701c70d1f34e7326afe20a 669 Gene3D G3DSA:1.20.1480.50 280 377 4.9E-18 T 14-10-2018 TSH58p_13815 7dac855d0d701c70d1f34e7326afe20a 669 SMART SM01358 39 291 4.2E-45 T 14-10-2018 IPR032255 Helical bimodular sensor domain TSH58p_13815 7dac855d0d701c70d1f34e7326afe20a 669 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 472 633 1.3E-29 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_13815 7dac855d0d701c70d1f34e7326afe20a 669 SMART SM00304 320 373 6.4E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_03145 21755e1626f6a8e26531d39a20ff3f1f 358 SMART SM00382 28 211 3.5E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_03145 21755e1626f6a8e26531d39a20ff3f1f 358 Pfam PF08402 TOBE domain 281 351 6.0E-12 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TSH58p_03145 21755e1626f6a8e26531d39a20ff3f1f 358 SUPERFAMILY SSF50331 236 358 1.02E-26 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSH58p_03145 21755e1626f6a8e26531d39a20ff3f1f 358 Gene3D G3DSA:2.40.50.940 222 351 3.5E-31 T 14-10-2018 TSH58p_03145 21755e1626f6a8e26531d39a20ff3f1f 358 SUPERFAMILY SSF52540 4 244 1.73E-85 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_03145 21755e1626f6a8e26531d39a20ff3f1f 358 Gene3D G3DSA:2.40.50.140 288 343 3.5E-31 T 14-10-2018 TSH58p_03145 21755e1626f6a8e26531d39a20ff3f1f 358 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_03145 21755e1626f6a8e26531d39a20ff3f1f 358 Gene3D G3DSA:3.40.50.300 4 221 9.5E-65 T 14-10-2018 TSH58p_03145 21755e1626f6a8e26531d39a20ff3f1f 358 Pfam PF00005 ABC transporter 20 161 1.9E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_31765 8ad3a4307ec22b83a7919139f59a613c 365 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_31765 8ad3a4307ec22b83a7919139f59a613c 365 Gene3D G3DSA:3.40.50.300 8 223 6.7E-69 T 14-10-2018 TSH58p_31765 8ad3a4307ec22b83a7919139f59a613c 365 SMART SM00382 35 218 5.2E-23 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_31765 8ad3a4307ec22b83a7919139f59a613c 365 Pfam PF00005 ABC transporter 26 168 2.0E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_31765 8ad3a4307ec22b83a7919139f59a613c 365 Gene3D G3DSA:2.40.50.940 227 354 6.6E-9 T 14-10-2018 TSH58p_31765 8ad3a4307ec22b83a7919139f59a613c 365 SUPERFAMILY SSF52540 10 248 3.0E-87 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_31765 8ad3a4307ec22b83a7919139f59a613c 365 SUPERFAMILY SSF50331 243 355 6.05E-13 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSH58p_31765 8ad3a4307ec22b83a7919139f59a613c 365 Pfam PF08402 TOBE domain 280 354 4.6E-8 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TSH58p_31765 8ad3a4307ec22b83a7919139f59a613c 365 Gene3D G3DSA:2.40.50.140 286 347 6.6E-9 T 14-10-2018 TSH58p_05145 e204f7e266be7de0b372b73d8cd0da2a 420 TIGRFAM TIGR04259 oxa_formateAnti: oxalate/formate antiporter 1 403 1.5E-187 T 14-10-2018 IPR026355 Oxalate/formate antiporter GO:0016021|GO:0019531|GO:0019532 TSH58p_05145 e204f7e266be7de0b372b73d8cd0da2a 420 Pfam PF07690 Major Facilitator Superfamily 7 260 3.0E-28 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_05145 e204f7e266be7de0b372b73d8cd0da2a 420 Gene3D G3DSA:1.20.1250.20 2 404 4.4E-49 T 14-10-2018 TSH58p_05145 e204f7e266be7de0b372b73d8cd0da2a 420 SUPERFAMILY SSF103473 3 398 1.12E-50 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_14600 8ba88d661146dee8085a9685ca9587ff 812 Gene3D G3DSA:1.10.287.950 441 744 1.5E-81 T 14-10-2018 TSH58p_14600 8ba88d661146dee8085a9685ca9587ff 812 SUPERFAMILY SSF158472 322 370 1.7E-10 T 14-10-2018 TSH58p_14600 8ba88d661146dee8085a9685ca9587ff 812 Gene3D G3DSA:1.20.1480.50 286 382 3.6E-16 T 14-10-2018 TSH58p_14600 8ba88d661146dee8085a9685ca9587ff 812 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 516 545 2.4E-50 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_14600 8ba88d661146dee8085a9685ca9587ff 812 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 593 620 2.4E-50 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_14600 8ba88d661146dee8085a9685ca9587ff 812 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 622 651 2.4E-50 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_14600 8ba88d661146dee8085a9685ca9587ff 812 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 670 699 2.4E-50 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_14600 8ba88d661146dee8085a9685ca9587ff 812 SMART SM00283 495 742 2.2E-99 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_14600 8ba88d661146dee8085a9685ca9587ff 812 Pfam PF00672 HAMP domain 322 370 1.3E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_14600 8ba88d661146dee8085a9685ca9587ff 812 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 554 710 2.9E-51 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_14600 8ba88d661146dee8085a9685ca9587ff 812 SMART SM00304 442 494 0.07 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_14600 8ba88d661146dee8085a9685ca9587ff 812 SMART SM00304 322 375 1.5E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_14600 8ba88d661146dee8085a9685ca9587ff 812 SMART SM01358 42 293 2.6E-31 T 14-10-2018 IPR032255 Helical bimodular sensor domain TSH58p_14600 8ba88d661146dee8085a9685ca9587ff 812 SUPERFAMILY SSF58104 462 743 3.27E-72 T 14-10-2018 TSH58p_05335 d74346696d60b16e8499f01e554509e1 104 Pfam PF03091 CutA1 divalent ion tolerance protein 5 101 8.7E-37 T 14-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 TSH58p_05335 d74346696d60b16e8499f01e554509e1 104 Gene3D G3DSA:3.30.70.120 1 104 2.3E-40 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TSH58p_05335 d74346696d60b16e8499f01e554509e1 104 SUPERFAMILY SSF54913 2 103 1.85E-35 T 14-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TSH58p_27975 e877925a2d37f4c3b0a55a8687d4450c 361 SUPERFAMILY SSF53335 202 353 2.97E-6 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_27975 e877925a2d37f4c3b0a55a8687d4450c 361 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 27 33 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TSH58p_27975 e877925a2d37f4c3b0a55a8687d4450c 361 SUPERFAMILY SSF53335 2 251 3.72E-71 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_27975 e877925a2d37f4c3b0a55a8687d4450c 361 Gene3D G3DSA:3.40.50.150 1 253 8.3E-69 T 14-10-2018 TSH58p_27975 e877925a2d37f4c3b0a55a8687d4450c 361 Pfam PF01555 DNA methylase 24 244 1.4E-55 T 14-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 TSH58p_27975 e877925a2d37f4c3b0a55a8687d4450c 361 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 229 249 5.9E-38 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 TSH58p_27975 e877925a2d37f4c3b0a55a8687d4450c 361 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 23 37 5.9E-38 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 TSH58p_27975 e877925a2d37f4c3b0a55a8687d4450c 361 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 206 224 5.9E-38 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 TSH58p_27975 e877925a2d37f4c3b0a55a8687d4450c 361 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 72 92 5.9E-38 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 TSH58p_27975 e877925a2d37f4c3b0a55a8687d4450c 361 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 187 204 5.9E-38 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 TSH58p_01775 fb513c930fb6e7b705e6f50eeaf4dc04 567 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 385 532 4.0E-29 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_01775 fb513c930fb6e7b705e6f50eeaf4dc04 567 Pfam PF00672 HAMP domain 219 261 3.1E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_01775 fb513c930fb6e7b705e6f50eeaf4dc04 567 Gene3D G3DSA:1.20.1480.50 176 275 1.2E-13 T 14-10-2018 TSH58p_01775 fb513c930fb6e7b705e6f50eeaf4dc04 567 SMART SM00283 307 561 5.9E-46 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_01775 fb513c930fb6e7b705e6f50eeaf4dc04 567 Pfam PF12729 Four helix bundle sensory module for signal transduction 14 186 2.3E-7 T 14-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain TSH58p_01775 fb513c930fb6e7b705e6f50eeaf4dc04 567 Gene3D G3DSA:1.10.287.950 276 561 2.0E-52 T 14-10-2018 TSH58p_01775 fb513c930fb6e7b705e6f50eeaf4dc04 567 SUPERFAMILY SSF58104 237 560 3.92E-61 T 14-10-2018 TSH58p_01775 fb513c930fb6e7b705e6f50eeaf4dc04 567 SMART SM00304 217 270 1.1E-5 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_24065 ec649b5796d29bd8d1ea899c5f167fb3 408 PIRSF PIRSF036428 5 408 1.8E-143 T 14-10-2018 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00860+2.1.1.132 TSH58p_24065 ec649b5796d29bd8d1ea899c5f167fb3 408 Gene3D G3DSA:3.40.50.150 221 406 2.9E-72 T 14-10-2018 TSH58p_24065 ec649b5796d29bd8d1ea899c5f167fb3 408 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 10 196 7.1E-21 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 TSH58p_24065 ec649b5796d29bd8d1ea899c5f167fb3 408 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 12 204 1.5E-45 T 14-10-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 TSH58p_24065 ec649b5796d29bd8d1ea899c5f167fb3 408 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 237 358 2.7E-33 T 14-10-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00860+2.1.1.196|MetaCyc: PWY-7377 TSH58p_24065 ec649b5796d29bd8d1ea899c5f167fb3 408 Gene3D G3DSA:3.40.1010.10 7 110 1.3E-16 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 TSH58p_24065 ec649b5796d29bd8d1ea899c5f167fb3 408 SUPERFAMILY SSF53790 9 211 4.71E-45 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 TSH58p_24065 ec649b5796d29bd8d1ea899c5f167fb3 408 SUPERFAMILY SSF53335 210 404 3.66E-29 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_32285 1a7fc199aec9e0f52244267bac474d63 648 Gene3D G3DSA:3.20.20.80 335 635 9.0E-73 T 14-10-2018 TSH58p_32285 1a7fc199aec9e0f52244267bac474d63 648 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 78 242 1.5E-22 T 14-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TSH58p_32285 1a7fc199aec9e0f52244267bac474d63 648 SUPERFAMILY SSF49785 72 242 1.42E-46 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily TSH58p_32285 1a7fc199aec9e0f52244267bac474d63 648 PRINTS PR00132 Glycosyl hydrolase family 2 signature 533 548 1.4E-10 T 14-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 TSH58p_32285 1a7fc199aec9e0f52244267bac474d63 648 PRINTS PR00132 Glycosyl hydrolase family 2 signature 344 358 1.4E-10 T 14-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 TSH58p_32285 1a7fc199aec9e0f52244267bac474d63 648 PRINTS PR00132 Glycosyl hydrolase family 2 signature 375 393 1.4E-10 T 14-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 TSH58p_32285 1a7fc199aec9e0f52244267bac474d63 648 PRINTS PR00132 Glycosyl hydrolase family 2 signature 168 183 1.4E-10 T 14-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 TSH58p_32285 1a7fc199aec9e0f52244267bac474d63 648 PRINTS PR00132 Glycosyl hydrolase family 2 signature 441 456 1.4E-10 T 14-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 TSH58p_32285 1a7fc199aec9e0f52244267bac474d63 648 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 335 621 1.8E-31 T 14-10-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 TSH58p_32285 1a7fc199aec9e0f52244267bac474d63 648 SUPERFAMILY SSF49303 245 334 6.12E-9 T 14-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily TSH58p_32285 1a7fc199aec9e0f52244267bac474d63 648 Gene3D G3DSA:2.60.40.10 256 333 1.9E-6 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_32285 1a7fc199aec9e0f52244267bac474d63 648 SUPERFAMILY SSF51445 335 626 3.84E-62 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_32285 1a7fc199aec9e0f52244267bac474d63 648 Gene3D G3DSA:2.60.120.260 70 242 9.3E-44 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily TSH58p_11865 f36167a6a1c3149eaa1058fa4609589b 166 SMART SM01058 6 116 5.9E-34 T 14-10-2018 IPR003711 CarD-like/TRCF domain TSH58p_11865 f36167a6a1c3149eaa1058fa4609589b 166 Pfam PF02559 CarD-like/TRCF domain 7 115 1.9E-19 T 14-10-2018 IPR003711 CarD-like/TRCF domain TSH58p_11865 f36167a6a1c3149eaa1058fa4609589b 166 Gene3D G3DSA:1.20.58.1290 68 163 2.3E-25 T 14-10-2018 TSH58p_11865 f36167a6a1c3149eaa1058fa4609589b 166 Gene3D G3DSA:2.30.30.840 1 67 1.2E-23 T 14-10-2018 TSH58p_11865 f36167a6a1c3149eaa1058fa4609589b 166 SUPERFAMILY SSF141259 3 72 1.01E-15 T 14-10-2018 IPR036101 CarD-like/TRCF domain superfamily TSH58p_02375 055e8b5c006c10c9bb5ed8e1e8658382 204 SUPERFAMILY SSF141488 124 200 1.57E-13 T 14-10-2018 IPR036328 C-type lysozyme inhibitor superfamily TSH58p_02375 055e8b5c006c10c9bb5ed8e1e8658382 204 Pfam PF09864 Membrane-bound lysozyme-inhibitor of c-type lysozyme 129 197 2.7E-13 T 14-10-2018 IPR018660 C-type lysozyme inhibitor TSH58p_02375 055e8b5c006c10c9bb5ed8e1e8658382 204 Gene3D G3DSA:2.40.128.200 125 202 6.6E-11 T 14-10-2018 IPR036328 C-type lysozyme inhibitor superfamily TSH58p_02375 055e8b5c006c10c9bb5ed8e1e8658382 204 Pfam PF07007 Lysozyme inhibitor LprI 38 114 2.0E-6 T 14-10-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal TSH58p_08490 09c01a5a136af0e5df613f1459ea6f61 436 SUPERFAMILY SSF117143 80 396 6.15E-65 T 14-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like TSH58p_08490 09c01a5a136af0e5df613f1459ea6f61 436 Pfam PF00460 Flagella basal body rod protein 7 37 1.0E-10 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 TSH58p_08490 09c01a5a136af0e5df613f1459ea6f61 436 Pfam PF07559 Flagellar basal body protein FlaE 182 316 1.1E-12 T 14-10-2018 IPR011491 Flagellar hook protein FlgE TSH58p_08490 09c01a5a136af0e5df613f1459ea6f61 436 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 357 434 6.4E-17 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain TSH58p_08490 09c01a5a136af0e5df613f1459ea6f61 436 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 14-10-2018 IPR019776 Flagellar basal body rod protein, conserved site TSH58p_08490 09c01a5a136af0e5df613f1459ea6f61 436 Gene3D G3DSA:2.60.98.20 152 317 3.4E-10 T 14-10-2018 IPR037058 Flagellar hook protein FlgE superfamily TSH58p_08490 09c01a5a136af0e5df613f1459ea6f61 436 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 5 416 1.4E-85 T 14-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G TSH58p_01995 02ea0ec6ad7c9641f39a468628e061ed 1252 PIRSF PIRSF000197 32 1252 0.0 T 14-10-2018 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 TSH58p_01995 02ea0ec6ad7c9641f39a468628e061ed 1252 Gene3D G3DSA:3.20.20.220 171 554 1.8E-146 T 14-10-2018 TSH58p_01995 02ea0ec6ad7c9641f39a468628e061ed 1252 Pfam PF01619 Proline dehydrogenase 224 517 3.7E-98 T 14-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 TSH58p_01995 02ea0ec6ad7c9641f39a468628e061ed 1252 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 853 864 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 TSH58p_01995 02ea0ec6ad7c9641f39a468628e061ed 1252 Gene3D G3DSA:3.40.605.10 580 1051 8.9E-142 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TSH58p_01995 02ea0ec6ad7c9641f39a468628e061ed 1252 Gene3D G3DSA:3.20.20.220 46 139 2.2E-14 T 14-10-2018 TSH58p_01995 02ea0ec6ad7c9641f39a468628e061ed 1252 Pfam PF14850 DNA-binding domain of Proline dehydrogenase 101 212 1.5E-44 T 14-10-2018 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 TSH58p_01995 02ea0ec6ad7c9641f39a468628e061ed 1252 TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase 554 1050 4.0E-230 T 14-10-2018 IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 GO:0003842|GO:0006561|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 TSH58p_01995 02ea0ec6ad7c9641f39a468628e061ed 1252 SUPERFAMILY SSF53720 590 1051 4.71E-127 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSH58p_01995 02ea0ec6ad7c9641f39a468628e061ed 1252 Pfam PF00171 Aldehyde dehydrogenase family 603 1046 2.5E-114 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TSH58p_01995 02ea0ec6ad7c9641f39a468628e061ed 1252 SUPERFAMILY SSF51730 215 562 1.49E-118 T 14-10-2018 IPR029041 FAD-linked oxidoreductase-like TSH58p_01995 02ea0ec6ad7c9641f39a468628e061ed 1252 Gene3D G3DSA:3.40.309.10 828 1020 8.9E-142 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TSH58p_01995 02ea0ec6ad7c9641f39a468628e061ed 1252 SUPERFAMILY SSF81935 46 214 1.31E-61 T 14-10-2018 IPR024089 Proline dehydrogenase PutA, domain I/II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 TSH58p_25935 870bb1d42321be4491846f030c478855 120 Gene3D G3DSA:3.40.960.10 15 112 5.9E-33 T 14-10-2018 TSH58p_25935 870bb1d42321be4491846f030c478855 120 SUPERFAMILY SSF52980 4 111 6.43E-24 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TSH58p_25935 870bb1d42321be4491846f030c478855 120 Pfam PF04480 Protein of unknown function (DUF559) 7 111 1.5E-36 T 14-10-2018 IPR007569 Protein of unknown function DUF559 TSH58p_04080 e670f1180da56915c0776c537f68e6e5 658 SUPERFAMILY SSF48435 37 486 6.93E-63 T 14-10-2018 IPR008939 Lytic transglycosylase, superhelical U-shaped GO:0004553|GO:0042597 TSH58p_04080 e670f1180da56915c0776c537f68e6e5 658 Gene3D G3DSA:1.25.20.10 33 400 1.1E-8 T 14-10-2018 TSH58p_04080 e670f1180da56915c0776c537f68e6e5 658 Pfam PF01464 Transglycosylase SLT domain 507 606 3.7E-26 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 TSH58p_04080 e670f1180da56915c0776c537f68e6e5 658 SUPERFAMILY SSF53955 506 644 3.87E-44 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily TSH58p_04080 e670f1180da56915c0776c537f68e6e5 658 Gene3D G3DSA:1.10.530.10 502 657 3.3E-46 T 14-10-2018 TSH58p_31820 83602207b9a66a3b3619e9a91e1d7f61 245 Gene3D G3DSA:1.10.3720.10 44 242 6.2E-19 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_31820 83602207b9a66a3b3619e9a91e1d7f61 245 SUPERFAMILY SSF161098 48 242 3.27E-22 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_31820 83602207b9a66a3b3619e9a91e1d7f61 245 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 71 240 1.8E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_18700 d9d54cf08cca748083a9f982cefd7067 133 SUPERFAMILY SSF55298 33 132 5.5E-28 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TSH58p_18700 d9d54cf08cca748083a9f982cefd7067 133 Pfam PF01042 Endoribonuclease L-PSP 33 132 3.1E-23 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 TSH58p_18700 d9d54cf08cca748083a9f982cefd7067 133 Gene3D G3DSA:3.30.1330.40 20 133 9.3E-31 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TSH58p_24440 f348dab49a2b1f09c603ae57a4318322 279 TIGRFAM TIGR02587 TIGR02587: putative integral membrane protein TIGR02587 15 279 7.0E-90 T 14-10-2018 IPR013416 Conserved hypothetical protein CHP02587, putative integral membrane TSH58p_24440 f348dab49a2b1f09c603ae57a4318322 279 Pfam PF09622 Putative integral membrane protein (DUF2391) 20 279 5.1E-93 T 14-10-2018 IPR024464 Protein of unknown function DUF2391 TSH58p_29735 4c9aa525f6bb4c26ea628100e8702653 208 SUPERFAMILY SSF52096 31 207 4.69E-56 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_29735 4c9aa525f6bb4c26ea628100e8702653 208 Gene3D G3DSA:3.90.226.10 25 207 1.1E-58 T 14-10-2018 TSH58p_29735 4c9aa525f6bb4c26ea628100e8702653 208 Pfam PF00574 Clp protease 31 203 4.0E-63 T 14-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA TSH58p_29735 4c9aa525f6bb4c26ea628100e8702653 208 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 15 204 32.536 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TSH58p_29735 4c9aa525f6bb4c26ea628100e8702653 208 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 123 136 - T 14-10-2018 IPR033135 ClpP, histidine active site TSH58p_29735 4c9aa525f6bb4c26ea628100e8702653 208 PRINTS PR00127 Clp protease catalytic subunit P signature 101 118 1.8E-24 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TSH58p_29735 4c9aa525f6bb4c26ea628100e8702653 208 PRINTS PR00127 Clp protease catalytic subunit P signature 70 90 1.8E-24 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TSH58p_29735 4c9aa525f6bb4c26ea628100e8702653 208 PRINTS PR00127 Clp protease catalytic subunit P signature 122 141 1.8E-24 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TSH58p_29735 4c9aa525f6bb4c26ea628100e8702653 208 PRINTS PR00127 Clp protease catalytic subunit P signature 179 198 1.8E-24 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TSH58p_29735 4c9aa525f6bb4c26ea628100e8702653 208 PRINTS PR00127 Clp protease catalytic subunit P signature 31 46 1.8E-24 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TSH58p_21805 78aae819d98aee31eb6a9c0d65a10e1f 525 Gene3D G3DSA:3.30.565.10 349 522 3.0E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_21805 78aae819d98aee31eb6a9c0d65a10e1f 525 Pfam PF00512 His Kinase A (phospho-acceptor) domain 280 348 2.0E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_21805 78aae819d98aee31eb6a9c0d65a10e1f 525 SUPERFAMILY SSF55785 137 257 1.24E-15 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_21805 78aae819d98aee31eb6a9c0d65a10e1f 525 PRINTS PR00344 Bacterial sensor protein C-terminal signature 498 511 2.1E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_21805 78aae819d98aee31eb6a9c0d65a10e1f 525 PRINTS PR00344 Bacterial sensor protein C-terminal signature 457 467 2.1E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_21805 78aae819d98aee31eb6a9c0d65a10e1f 525 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 453 2.1E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_21805 78aae819d98aee31eb6a9c0d65a10e1f 525 PRINTS PR00344 Bacterial sensor protein C-terminal signature 470 488 2.1E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_21805 78aae819d98aee31eb6a9c0d65a10e1f 525 SMART SM00388 279 349 4.2E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_21805 78aae819d98aee31eb6a9c0d65a10e1f 525 Gene3D G3DSA:1.10.287.130 284 346 6.2E-18 T 14-10-2018 TSH58p_21805 78aae819d98aee31eb6a9c0d65a10e1f 525 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 392 512 3.7E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_21805 78aae819d98aee31eb6a9c0d65a10e1f 525 Gene3D G3DSA:3.30.450.20 132 276 4.0E-23 T 14-10-2018 TSH58p_21805 78aae819d98aee31eb6a9c0d65a10e1f 525 SUPERFAMILY SSF55874 345 516 1.09E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_21805 78aae819d98aee31eb6a9c0d65a10e1f 525 SMART SM00387 390 514 2.4E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_21805 78aae819d98aee31eb6a9c0d65a10e1f 525 Pfam PF08448 PAS fold 154 266 2.0E-15 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_21805 78aae819d98aee31eb6a9c0d65a10e1f 525 SUPERFAMILY SSF47384 276 347 3.34E-11 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_21805 78aae819d98aee31eb6a9c0d65a10e1f 525 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 146 271 1.2E-12 T 14-10-2018 IPR000014 PAS domain TSH58p_07250 db410233265d338e17b152544bb98fb3 131 Pfam PF01844 HNH endonuclease 67 111 1.7E-6 T 14-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 TSH58p_07250 db410233265d338e17b152544bb98fb3 131 SMART SM00507 55 110 7.6E-5 T 14-10-2018 IPR003615 HNH nuclease TSH58p_21230 3a6ad427ecee9449f342e0886cd58b1d 379 Gene3D G3DSA:3.40.50.2300 151 370 7.6E-68 T 14-10-2018 TSH58p_21230 3a6ad427ecee9449f342e0886cd58b1d 379 Gene3D G3DSA:3.40.50.2300 47 305 7.6E-68 T 14-10-2018 TSH58p_21230 3a6ad427ecee9449f342e0886cd58b1d 379 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 47 292 2.9E-17 T 14-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 TSH58p_15790 458455ac3d4076603de86f8d93394e9d 258 Gene3D G3DSA:2.40.10.10 23 201 3.0E-22 T 14-10-2018 TSH58p_15790 458455ac3d4076603de86f8d93394e9d 258 Pfam PF13365 Trypsin-like peptidase domain 53 200 4.3E-10 T 14-10-2018 TSH58p_15790 458455ac3d4076603de86f8d93394e9d 258 Gene3D G3DSA:2.40.10.10 38 138 3.0E-22 T 14-10-2018 TSH58p_15790 458455ac3d4076603de86f8d93394e9d 258 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 64 69 - T 14-10-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 TSH58p_15790 458455ac3d4076603de86f8d93394e9d 258 SUPERFAMILY SSF50494 7 244 8.51E-25 T 14-10-2018 IPR009003 Peptidase S1, PA clan TSH58p_15790 458455ac3d4076603de86f8d93394e9d 258 PRINTS PR00839 V8 serine protease family signature 147 160 4.3E-9 T 14-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 TSH58p_15790 458455ac3d4076603de86f8d93394e9d 258 PRINTS PR00839 V8 serine protease family signature 53 70 4.3E-9 T 14-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 TSH58p_15790 458455ac3d4076603de86f8d93394e9d 258 PRINTS PR00839 V8 serine protease family signature 184 200 4.3E-9 T 14-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 TSH58p_15790 458455ac3d4076603de86f8d93394e9d 258 PRINTS PR00839 V8 serine protease family signature 28 45 4.3E-9 T 14-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 TSH58p_32465 bcc4e73ec72a1c3accdc3b30c14deaa7 475 SUPERFAMILY SSF52540 160 404 7.59E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_32465 bcc4e73ec72a1c3accdc3b30c14deaa7 475 SUPERFAMILY SSF46689 374 469 2.69E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_32465 bcc4e73ec72a1c3accdc3b30c14deaa7 475 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 184 197 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 TSH58p_32465 bcc4e73ec72a1c3accdc3b30c14deaa7 475 SUPERFAMILY SSF55785 14 117 7.67E-8 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_32465 bcc4e73ec72a1c3accdc3b30c14deaa7 475 Gene3D G3DSA:3.40.50.300 148 331 6.4E-63 T 14-10-2018 TSH58p_32465 bcc4e73ec72a1c3accdc3b30c14deaa7 475 Pfam PF02954 Bacterial regulatory protein, Fis family 427 467 2.6E-12 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_32465 bcc4e73ec72a1c3accdc3b30c14deaa7 475 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 247 262 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 TSH58p_32465 bcc4e73ec72a1c3accdc3b30c14deaa7 475 SMART SM00382 180 325 2.1E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_32465 bcc4e73ec72a1c3accdc3b30c14deaa7 475 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 450 470 3.1E-12 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_32465 bcc4e73ec72a1c3accdc3b30c14deaa7 475 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 433 450 3.1E-12 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_32465 bcc4e73ec72a1c3accdc3b30c14deaa7 475 Pfam PF08448 PAS fold 21 118 4.4E-7 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_32465 bcc4e73ec72a1c3accdc3b30c14deaa7 475 Pfam PF00158 Sigma-54 interaction domain 160 328 3.5E-65 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 TSH58p_32465 bcc4e73ec72a1c3accdc3b30c14deaa7 475 Gene3D G3DSA:1.10.8.60 332 409 6.9E-19 T 14-10-2018 TSH58p_32465 bcc4e73ec72a1c3accdc3b30c14deaa7 475 Gene3D G3DSA:1.10.10.60 418 472 3.1E-15 T 14-10-2018 TSH58p_32465 bcc4e73ec72a1c3accdc3b30c14deaa7 475 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 374 383 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site TSH58p_32465 bcc4e73ec72a1c3accdc3b30c14deaa7 475 Gene3D G3DSA:3.30.450.20 3 118 4.3E-9 T 14-10-2018 TSH58p_04025 171694a6bbfed919dcba9aec0b0635dd 417 Gene3D G3DSA:3.40.50.150 117 383 4.6E-96 T 14-10-2018 TSH58p_04025 171694a6bbfed919dcba9aec0b0635dd 417 SUPERFAMILY SSF53335 119 379 1.84E-80 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_04025 171694a6bbfed919dcba9aec0b0635dd 417 Pfam PF02353 Mycolic acid cyclopropane synthetase 111 374 1.3E-89 T 14-10-2018 TSH58p_04025 171694a6bbfed919dcba9aec0b0635dd 417 PIRSF PIRSF003085 1 396 1.8E-137 T 14-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 TSH58p_15530 21dde6422038a2db717da25265efcee6 889 Pfam PF02272 DHHA1 domain 742 883 4.3E-20 T 14-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TSH58p_15530 21dde6422038a2db717da25265efcee6 889 SMART SM00863 654 705 6.5E-22 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TSH58p_15530 21dde6422038a2db717da25265efcee6 889 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 654 705 7.9E-18 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TSH58p_15530 21dde6422038a2db717da25265efcee6 889 SUPERFAMILY SSF101353 246 461 6.41E-59 T 14-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 TSH58p_15530 21dde6422038a2db717da25265efcee6 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 274 290 7.5E-33 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TSH58p_15530 21dde6422038a2db717da25265efcee6 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 298 311 7.5E-33 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TSH58p_15530 21dde6422038a2db717da25265efcee6 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 75 86 7.5E-33 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TSH58p_15530 21dde6422038a2db717da25265efcee6 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 7.5E-33 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TSH58p_15530 21dde6422038a2db717da25265efcee6 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 226 239 7.5E-33 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TSH58p_15530 21dde6422038a2db717da25265efcee6 889 Pfam PF01411 tRNA synthetases class II (A) 6 557 4.3E-220 T 14-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 TSH58p_15530 21dde6422038a2db717da25265efcee6 889 Gene3D G3DSA:3.30.54.20 625 686 7.0E-47 T 14-10-2018 TSH58p_15530 21dde6422038a2db717da25265efcee6 889 SUPERFAMILY SSF50447 453 553 1.46E-20 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSH58p_15530 21dde6422038a2db717da25265efcee6 889 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 887 198.608 T 14-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 TSH58p_15530 21dde6422038a2db717da25265efcee6 889 Gene3D G3DSA:2.40.30.130 460 553 1.4E-9 T 14-10-2018 TSH58p_15530 21dde6422038a2db717da25265efcee6 889 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 6 866 1.6E-294 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TSH58p_15530 21dde6422038a2db717da25265efcee6 889 SUPERFAMILY SSF55186 553 721 1.27E-47 T 14-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 TSH58p_15530 21dde6422038a2db717da25265efcee6 889 Gene3D G3DSA:3.30.980.10 564 706 7.0E-47 T 14-10-2018 TSH58p_15530 21dde6422038a2db717da25265efcee6 889 Gene3D G3DSA:3.10.310.40 774 885 2.0E-28 T 14-10-2018 TSH58p_15530 21dde6422038a2db717da25265efcee6 889 Gene3D G3DSA:3.30.930.10 1 241 3.8E-109 T 14-10-2018 TSH58p_15530 21dde6422038a2db717da25265efcee6 889 SUPERFAMILY SSF55681 3 245 4.97E-109 T 14-10-2018 TSH58p_28030 0858e9aa8030ac9bbaf2b9e0fdc707c4 113 TIGRFAM TIGR00100 hypA: hydrogenase nickel insertion protein HypA 1 113 1.7E-28 T 14-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 TSH58p_28030 0858e9aa8030ac9bbaf2b9e0fdc707c4 113 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 112 3.3E-31 T 14-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 TSH58p_28030 0858e9aa8030ac9bbaf2b9e0fdc707c4 113 Hamap MF_00213 Hydrogenase maturation factor HypA [hypA]. 1 113 22.029 T 14-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 TSH58p_28030 0858e9aa8030ac9bbaf2b9e0fdc707c4 113 PIRSF PIRSF004761 1 113 4.2E-34 T 14-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 TSH58p_28030 0858e9aa8030ac9bbaf2b9e0fdc707c4 113 Gene3D G3DSA:3.30.2320.80 1 113 2.1E-29 T 14-10-2018 TSH58p_13830 562e70074f30178f4f2bdfa93e32acdb 392 Gene3D G3DSA:3.40.710.10 32 378 2.4E-75 T 14-10-2018 TSH58p_13830 562e70074f30178f4f2bdfa93e32acdb 392 Pfam PF00144 Beta-lactamase 38 371 3.8E-54 T 14-10-2018 IPR001466 Beta-lactamase-related TSH58p_13830 562e70074f30178f4f2bdfa93e32acdb 392 SUPERFAMILY SSF56601 31 370 1.82E-68 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TSH58p_09105 8686d4907ae7d4c076c2e48e718c0e9c 529 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 2.0E-13 T 14-10-2018 TSH58p_09105 8686d4907ae7d4c076c2e48e718c0e9c 529 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 326 348 2.0E-13 T 14-10-2018 TSH58p_09105 8686d4907ae7d4c076c2e48e718c0e9c 529 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 208 226 2.0E-13 T 14-10-2018 TSH58p_09105 8686d4907ae7d4c076c2e48e718c0e9c 529 Pfam PF00890 FAD binding domain 12 221 1.5E-14 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_09105 8686d4907ae7d4c076c2e48e718c0e9c 529 SUPERFAMILY SSF51905 6 386 1.2E-45 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_09105 8686d4907ae7d4c076c2e48e718c0e9c 529 SUPERFAMILY SSF46977 419 504 1.01E-14 T 14-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_09105 8686d4907ae7d4c076c2e48e718c0e9c 529 Gene3D G3DSA:3.50.50.60 3 272 4.9E-43 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_09105 8686d4907ae7d4c076c2e48e718c0e9c 529 Gene3D G3DSA:1.20.58.100 406 499 7.8E-7 T 14-10-2018 TSH58p_09105 8686d4907ae7d4c076c2e48e718c0e9c 529 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 12 34 3.9E-8 T 14-10-2018 TSH58p_09105 8686d4907ae7d4c076c2e48e718c0e9c 529 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 341 348 3.9E-8 T 14-10-2018 TSH58p_16490 37d89a0624ec50b21f9b9c446616d0a6 344 SUPERFAMILY SSF58104 17 83 2.35E-20 T 14-10-2018 TSH58p_16490 37d89a0624ec50b21f9b9c446616d0a6 344 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 20 76 2.6E-15 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_16490 37d89a0624ec50b21f9b9c446616d0a6 344 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 22 49 7.5E-10 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_16490 37d89a0624ec50b21f9b9c446616d0a6 344 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 51 80 7.5E-10 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_16490 37d89a0624ec50b21f9b9c446616d0a6 344 Gene3D G3DSA:1.10.287.950 3 110 2.3E-19 T 14-10-2018 TSH58p_16490 37d89a0624ec50b21f9b9c446616d0a6 344 Gene3D G3DSA:3.30.450.20 121 245 6.4E-10 T 14-10-2018 TSH58p_05740 92d36e8b1fd91278de63b60e20da4875 396 SUPERFAMILY SSF69055 300 391 6.54E-29 T 14-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TSH58p_05740 92d36e8b1fd91278de63b60e20da4875 396 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 15 140 4.1E-41 T 14-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TSH58p_05740 92d36e8b1fd91278de63b60e20da4875 396 Pfam PF13288 DXP reductoisomerase C-terminal domain 269 385 7.3E-40 T 14-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TSH58p_05740 92d36e8b1fd91278de63b60e20da4875 396 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 15 390 45.816 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TSH58p_05740 92d36e8b1fd91278de63b60e20da4875 396 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 154 237 1.5E-36 T 14-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TSH58p_05740 92d36e8b1fd91278de63b60e20da4875 396 SUPERFAMILY SSF51735 12 158 3.74E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_05740 92d36e8b1fd91278de63b60e20da4875 396 Gene3D G3DSA:1.10.1740.10 311 396 9.8E-26 T 14-10-2018 TSH58p_05740 92d36e8b1fd91278de63b60e20da4875 396 SUPERFAMILY SSF55347 134 272 1.41E-58 T 14-10-2018 TSH58p_05740 92d36e8b1fd91278de63b60e20da4875 396 Gene3D G3DSA:3.40.50.720 10 158 1.7E-52 T 14-10-2018 TSH58p_05740 92d36e8b1fd91278de63b60e20da4875 396 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 14 394 2.1E-138 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TSH58p_05740 92d36e8b1fd91278de63b60e20da4875 396 PIRSF PIRSF006205 12 395 2.7E-147 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TSH58p_23500 94e65351ddf6fb8e161afd61da4c2080 211 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 53 207 1.4E-35 T 14-10-2018 IPR005586 ABC-type transport auxiliary lipoprotein component TSH58p_23500 94e65351ddf6fb8e161afd61da4c2080 211 SUPERFAMILY SSF159594 34 210 4.45E-27 T 14-10-2018 TSH58p_23500 94e65351ddf6fb8e161afd61da4c2080 211 Gene3D G3DSA:3.40.50.10610 25 210 3.9E-8 T 14-10-2018 TSH58p_12105 78a3cd8d7a6537bce0c2ffc0074aa8ab 234 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 219 6.9E-19 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_12105 78a3cd8d7a6537bce0c2ffc0074aa8ab 234 Gene3D G3DSA:1.10.3720.10 11 231 9.0E-41 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_12105 78a3cd8d7a6537bce0c2ffc0074aa8ab 234 SUPERFAMILY SSF161098 14 213 6.93E-36 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_12105 78a3cd8d7a6537bce0c2ffc0074aa8ab 234 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 15 122 3.2E-17 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 TSH58p_03930 582cb84bcde592a230492438015ebad9 520 SUPERFAMILY SSF52540 155 410 1.51E-24 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_03930 582cb84bcde592a230492438015ebad9 520 SMART SM00382 174 343 0.0035 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_03930 582cb84bcde592a230492438015ebad9 520 Pfam PF13401 AAA domain 174 324 4.4E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_03930 582cb84bcde592a230492438015ebad9 520 Gene3D G3DSA:3.40.50.300 146 338 1.9E-14 T 14-10-2018 TSH58p_30855 628abfe47b5d606b57d407d6733c37ea 243 SMART SM00895 109 232 2.4E-23 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_30855 628abfe47b5d606b57d407d6733c37ea 243 Gene3D G3DSA:1.10.10.10 38 97 9.6E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_30855 628abfe47b5d606b57d407d6733c37ea 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 41 96 3.6E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_30855 628abfe47b5d606b57d407d6733c37ea 243 SMART SM00345 43 99 1.1E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_30855 628abfe47b5d606b57d407d6733c37ea 243 Gene3D G3DSA:1.20.120.530 98 239 5.3E-29 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_30855 628abfe47b5d606b57d407d6733c37ea 243 SUPERFAMILY SSF46785 39 103 6.54E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_30855 628abfe47b5d606b57d407d6733c37ea 243 Pfam PF07729 FCD domain 110 231 1.8E-25 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_30855 628abfe47b5d606b57d407d6733c37ea 243 SUPERFAMILY SSF48008 106 241 3.4E-26 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_30285 8f6cf765c387ca9f6ad5446f629ae90a 237 SMART SM00419 173 221 1.0E-13 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_30285 8f6cf765c387ca9f6ad5446f629ae90a 237 Pfam PF00027 Cyclic nucleotide-binding domain 35 122 2.6E-16 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_30285 8f6cf765c387ca9f6ad5446f629ae90a 237 SUPERFAMILY SSF46785 152 230 3.87E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_30285 8f6cf765c387ca9f6ad5446f629ae90a 237 Pfam PF13545 Crp-like helix-turn-helix domain 155 227 3.2E-18 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_30285 8f6cf765c387ca9f6ad5446f629ae90a 237 Gene3D G3DSA:1.10.10.10 151 233 7.5E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_30285 8f6cf765c387ca9f6ad5446f629ae90a 237 Gene3D G3DSA:2.60.120.10 5 150 2.7E-34 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_30285 8f6cf765c387ca9f6ad5446f629ae90a 237 SUPERFAMILY SSF51206 10 148 8.12E-32 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like TSH58p_30285 8f6cf765c387ca9f6ad5446f629ae90a 237 SMART SM00100 16 134 8.4E-19 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_30285 8f6cf765c387ca9f6ad5446f629ae90a 237 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 195 210 6.2E-6 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_30285 8f6cf765c387ca9f6ad5446f629ae90a 237 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 179 195 6.2E-6 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_05935 1d36253273b453ffa3442f0283f93ea4 804 Gene3D G3DSA:3.30.230.10 593 779 2.1E-79 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSH58p_05935 1d36253273b453ffa3442f0283f93ea4 804 TIGRFAM TIGR00763 lon: endopeptidase La 11 771 8.8E-303 T 14-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 TSH58p_05935 1d36253273b453ffa3442f0283f93ea4 804 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 595 611 1.9E-54 T 14-10-2018 TSH58p_05935 1d36253273b453ffa3442f0283f93ea4 804 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 673 692 1.9E-54 T 14-10-2018 TSH58p_05935 1d36253273b453ffa3442f0283f93ea4 804 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 703 722 1.9E-54 T 14-10-2018 TSH58p_05935 1d36253273b453ffa3442f0283f93ea4 804 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 355 374 1.9E-54 T 14-10-2018 TSH58p_05935 1d36253273b453ffa3442f0283f93ea4 804 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 726 744 1.9E-54 T 14-10-2018 TSH58p_05935 1d36253273b453ffa3442f0283f93ea4 804 Hamap MF_01973 Lon protease [lon]. 10 772 72.101 T 14-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 TSH58p_05935 1d36253273b453ffa3442f0283f93ea4 804 SUPERFAMILY SSF88697 11 200 1.47E-50 T 14-10-2018 IPR015947 PUA-like superfamily TSH58p_05935 1d36253273b453ffa3442f0283f93ea4 804 Gene3D G3DSA:3.40.50.300 313 489 2.4E-63 T 14-10-2018 TSH58p_05935 1d36253273b453ffa3442f0283f93ea4 804 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 351 487 1.9E-20 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSH58p_05935 1d36253273b453ffa3442f0283f93ea4 804 SUPERFAMILY SSF52540 313 586 1.44E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_05935 1d36253273b453ffa3442f0283f93ea4 804 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 10 200 1.2E-42 T 14-10-2018 IPR003111 Lon, substrate-binding domain TSH58p_05935 1d36253273b453ffa3442f0283f93ea4 804 Gene3D G3DSA:1.10.8.60 490 584 5.7E-30 T 14-10-2018 TSH58p_05935 1d36253273b453ffa3442f0283f93ea4 804 SMART SM00382 347 504 7.8E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_05935 1d36253273b453ffa3442f0283f93ea4 804 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 676 684 - T 14-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 TSH58p_05935 1d36253273b453ffa3442f0283f93ea4 804 SMART SM00464 9 201 7.7E-87 T 14-10-2018 IPR003111 Lon, substrate-binding domain TSH58p_05935 1d36253273b453ffa3442f0283f93ea4 804 Gene3D G3DSA:1.20.58.1480 120 244 1.0E-45 T 14-10-2018 TSH58p_05935 1d36253273b453ffa3442f0283f93ea4 804 PIRSF PIRSF001174 2 775 0.0 T 14-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 TSH58p_05935 1d36253273b453ffa3442f0283f93ea4 804 SUPERFAMILY SSF54211 595 770 8.34E-58 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSH58p_05935 1d36253273b453ffa3442f0283f93ea4 804 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 570 772 2.4E-98 T 14-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 TSH58p_05935 1d36253273b453ffa3442f0283f93ea4 804 Gene3D G3DSA:2.30.130.40 8 116 1.9E-33 T 14-10-2018 TSH58p_02010 faa9b43dd720e90905baddff3dc95beb 235 Pfam PF06904 Extensin-like protein C-terminus 63 235 2.8E-64 T 14-10-2018 IPR009683 Extensin-like, C-terminal TSH58p_26920 431aeb82ce673488513384d5980114c8 165 Gene3D G3DSA:1.20.1260.10 1 164 3.4E-65 T 14-10-2018 IPR012347 Ferritin-like TSH58p_26920 431aeb82ce673488513384d5980114c8 165 Pfam PF05974 Domain of unknown function (DUF892) 6 161 4.8E-59 T 14-10-2018 IPR010287 Domain of unknown function DUF892 TSH58p_26920 431aeb82ce673488513384d5980114c8 165 SUPERFAMILY SSF47240 1 154 9.53E-53 T 14-10-2018 IPR009078 Ferritin-like superfamily TSH58p_20815 df73011a032280822bce6ab8b0a0bdab 588 Gene3D G3DSA:3.40.50.300 341 587 6.9E-89 T 14-10-2018 TSH58p_20815 df73011a032280822bce6ab8b0a0bdab 588 SMART SM00382 371 557 8.1E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_20815 df73011a032280822bce6ab8b0a0bdab 588 Pfam PF00664 ABC transporter transmembrane region 33 292 3.7E-17 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TSH58p_20815 df73011a032280822bce6ab8b0a0bdab 588 SUPERFAMILY SSF52540 339 581 1.3E-85 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_20815 df73011a032280822bce6ab8b0a0bdab 588 Pfam PF00005 ABC transporter 362 511 4.9E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_20815 df73011a032280822bce6ab8b0a0bdab 588 ProSitePatterns PS00211 ABC transporters family signature. 483 497 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_20815 df73011a032280822bce6ab8b0a0bdab 588 Gene3D G3DSA:1.20.1560.10 12 333 1.9E-43 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_20815 df73011a032280822bce6ab8b0a0bdab 588 SUPERFAMILY SSF90123 15 335 5.23E-46 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_22040 1559b3206d7a3084ca9de0e1c41a8b85 526 Gene3D G3DSA:1.20.1440.230 432 525 2.1E-26 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_22040 1559b3206d7a3084ca9de0e1c41a8b85 526 SUPERFAMILY SSF142019 105 345 9.29E-87 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_22040 1559b3206d7a3084ca9de0e1c41a8b85 526 SUPERFAMILY SSF142984 348 429 4.71E-20 T 14-10-2018 TSH58p_22040 1559b3206d7a3084ca9de0e1c41a8b85 526 Gene3D G3DSA:3.10.20.600 337 431 3.2E-22 T 14-10-2018 TSH58p_22040 1559b3206d7a3084ca9de0e1c41a8b85 526 Gene3D G3DSA:3.40.50.11540 158 336 2.1E-70 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_22040 1559b3206d7a3084ca9de0e1c41a8b85 526 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 272 287 - T 14-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_22040 1559b3206d7a3084ca9de0e1c41a8b85 526 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 447 458 - T 14-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_22040 1559b3206d7a3084ca9de0e1c41a8b85 526 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 153 324 5.7E-44 T 14-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_22040 1559b3206d7a3084ca9de0e1c41a8b85 526 SUPERFAMILY SSF140490 430 518 7.06E-30 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_22040 1559b3206d7a3084ca9de0e1c41a8b85 526 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 436 517 4.1E-30 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_22040 1559b3206d7a3084ca9de0e1c41a8b85 526 SMART SM00928 434 479 1.6E-19 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_21360 c6e7eaa495452c56a255ff5251967763 308 PIRSF PIRSF001365 4 307 1.4E-46 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_21360 c6e7eaa495452c56a255ff5251967763 308 SMART SM01130 7 300 6.3E-59 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_21360 c6e7eaa495452c56a255ff5251967763 308 Gene3D G3DSA:3.20.20.70 1 308 3.9E-104 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_21360 c6e7eaa495452c56a255ff5251967763 308 SUPERFAMILY SSF51569 5 302 8.58E-65 T 14-10-2018 TSH58p_21360 c6e7eaa495452c56a255ff5251967763 308 Pfam PF00701 Dihydrodipicolinate synthetase family 9 283 3.2E-27 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_11885 90e4e838de874de24c4042f1692683ab 507 Pfam PF01435 Peptidase family M48 85 268 2.7E-34 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 TSH58p_11885 90e4e838de874de24c4042f1692683ab 507 Gene3D G3DSA:3.30.2010.10 79 159 8.5E-6 T 14-10-2018 TSH58p_16125 aeda564814d62d93a6db01e2af93fcf1 190 SUPERFAMILY SSF52980 9 184 5.04E-22 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TSH58p_16125 aeda564814d62d93a6db01e2af93fcf1 190 Gene3D G3DSA:3.90.1570.10 6 188 6.7E-18 T 14-10-2018 TSH58p_16125 aeda564814d62d93a6db01e2af93fcf1 190 Pfam PF05685 Putative restriction endonuclease 17 172 7.4E-25 T 14-10-2018 IPR008538 Domain of unknown function DUF820 TSH58p_26830 e9f609f4dbfabc254e2cc8d0d894b6ba 334 Gene3D G3DSA:3.40.190.10 41 294 4.1E-35 T 14-10-2018 TSH58p_26830 e9f609f4dbfabc254e2cc8d0d894b6ba 334 Pfam PF09084 NMT1/THI5 like 46 251 6.1E-28 T 14-10-2018 IPR015168 SsuA/THI5-like TSH58p_26830 e9f609f4dbfabc254e2cc8d0d894b6ba 334 SUPERFAMILY SSF53850 31 254 1.57E-31 T 14-10-2018 TSH58p_26830 e9f609f4dbfabc254e2cc8d0d894b6ba 334 Gene3D G3DSA:3.40.190.10 111 214 4.1E-35 T 14-10-2018 TSH58p_08140 e81cf4580e5f63ee1fde30ab843f9faf 318 Gene3D G3DSA:2.40.30.30 187 317 6.8E-41 T 14-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 TSH58p_08140 e81cf4580e5f63ee1fde30ab843f9faf 318 SMART SM00904 184 311 1.8E-60 T 14-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 TSH58p_08140 e81cf4580e5f63ee1fde30ab843f9faf 318 Pfam PF06574 FAD synthetase 12 166 2.8E-52 T 14-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 TSH58p_08140 e81cf4580e5f63ee1fde30ab843f9faf 318 SUPERFAMILY SSF52374 17 178 1.41E-32 T 14-10-2018 TSH58p_08140 e81cf4580e5f63ee1fde30ab843f9faf 318 SUPERFAMILY SSF82114 175 313 8.5E-42 T 14-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 TSH58p_08140 e81cf4580e5f63ee1fde30ab843f9faf 318 Pfam PF01687 Riboflavin kinase 185 310 1.8E-36 T 14-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 TSH58p_08140 e81cf4580e5f63ee1fde30ab843f9faf 318 Gene3D G3DSA:3.40.50.620 1 186 1.7E-58 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_08140 e81cf4580e5f63ee1fde30ab843f9faf 318 PIRSF PIRSF004491 1 317 2.7E-97 T 14-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 TSH58p_08140 e81cf4580e5f63ee1fde30ab843f9faf 318 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 19 310 2.7E-79 T 14-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 TSH58p_29160 62f1c8abbc8e8bfa3b6b1493a6faafd4 375 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 25 50 3.5E-7 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 TSH58p_29160 62f1c8abbc8e8bfa3b6b1493a6faafd4 375 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 95 115 3.5E-7 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 TSH58p_29160 62f1c8abbc8e8bfa3b6b1493a6faafd4 375 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 55 70 3.5E-7 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 TSH58p_29160 62f1c8abbc8e8bfa3b6b1493a6faafd4 375 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 139 165 3.5E-7 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 TSH58p_29160 62f1c8abbc8e8bfa3b6b1493a6faafd4 375 SUPERFAMILY SSF55961 156 374 1.26E-25 T 14-10-2018 TSH58p_29160 62f1c8abbc8e8bfa3b6b1493a6faafd4 375 Gene3D G3DSA:2.102.10.10 38 164 1.3E-28 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TSH58p_29160 62f1c8abbc8e8bfa3b6b1493a6faafd4 375 Pfam PF00355 Rieske [2Fe-2S] domain 41 122 1.5E-13 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TSH58p_29160 62f1c8abbc8e8bfa3b6b1493a6faafd4 375 SUPERFAMILY SSF50022 12 153 3.01E-34 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TSH58p_29160 62f1c8abbc8e8bfa3b6b1493a6faafd4 375 Gene3D G3DSA:3.90.380.10 214 375 1.1E-10 T 14-10-2018 TSH58p_29160 62f1c8abbc8e8bfa3b6b1493a6faafd4 375 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 185 373 4.9E-23 T 14-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 TSH58p_31855 d501e9ab7cffdcf6125e84fdc41159b7 270 PIRSF PIRSF018982 5 263 1.5E-91 T 14-10-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 TSH58p_31855 d501e9ab7cffdcf6125e84fdc41159b7 270 Pfam PF05985 Ethanolamine ammonia-lyase light chain (EutC) 21 253 3.2E-90 T 14-10-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 TSH58p_31855 d501e9ab7cffdcf6125e84fdc41159b7 270 Gene3D G3DSA:3.40.50.11240 75 253 5.9E-64 T 14-10-2018 TSH58p_31855 d501e9ab7cffdcf6125e84fdc41159b7 270 Gene3D G3DSA:1.10.30.40 11 65 1.2E-9 T 14-10-2018 TSH58p_19905 0c0fa1dcc871606aea9cae46d434749d 142 SMART SM00344 2 108 2.8E-27 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TSH58p_19905 0c0fa1dcc871606aea9cae46d434749d 142 SUPERFAMILY SSF54909 64 141 1.61E-17 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel TSH58p_19905 0c0fa1dcc871606aea9cae46d434749d 142 Gene3D G3DSA:1.10.10.10 1 53 4.2E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_19905 0c0fa1dcc871606aea9cae46d434749d 142 Pfam PF01037 Lrp/AsnC ligand binding domain 68 137 2.7E-16 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TSH58p_19905 0c0fa1dcc871606aea9cae46d434749d 142 SUPERFAMILY SSF46785 1 58 2.44E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_19905 0c0fa1dcc871606aea9cae46d434749d 142 Pfam PF13404 AsnC-type helix-turn-helix domain 2 43 7.9E-15 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSH58p_19905 0c0fa1dcc871606aea9cae46d434749d 142 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 2.1E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSH58p_19905 0c0fa1dcc871606aea9cae46d434749d 142 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 2.1E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSH58p_19905 0c0fa1dcc871606aea9cae46d434749d 142 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 2.1E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSH58p_19905 0c0fa1dcc871606aea9cae46d434749d 142 Gene3D G3DSA:3.30.70.920 55 142 7.5E-19 T 14-10-2018 TSH58p_11545 540007cc33658fceda2cce1e2c6b9a5d 509 Gene3D G3DSA:3.30.300.180 9 105 7.9E-13 T 14-10-2018 IPR038454 DnaA, N-terminal domain superfamily TSH58p_11545 540007cc33658fceda2cce1e2c6b9a5d 509 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 8 508 32.516 T 14-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 TSH58p_11545 540007cc33658fceda2cce1e2c6b9a5d 509 Pfam PF00308 Bacterial dnaA protein 174 390 4.2E-91 T 14-10-2018 IPR013317 Chromosomal replication initiator protein DnaA TSH58p_11545 540007cc33658fceda2cce1e2c6b9a5d 509 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 418 486 4.6E-31 T 14-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 TSH58p_11545 540007cc33658fceda2cce1e2c6b9a5d 509 SUPERFAMILY SSF52540 173 386 2.23E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_11545 540007cc33658fceda2cce1e2c6b9a5d 509 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 11 507 6.9E-170 T 14-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 TSH58p_11545 540007cc33658fceda2cce1e2c6b9a5d 509 SMART SM00760 417 486 8.7E-42 T 14-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 TSH58p_11545 540007cc33658fceda2cce1e2c6b9a5d 509 Gene3D G3DSA:1.10.1750.10 410 508 2.4E-36 T 14-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 TSH58p_11545 540007cc33658fceda2cce1e2c6b9a5d 509 ProSitePatterns PS01008 DnaA protein signature. 467 486 - T 14-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 TSH58p_11545 540007cc33658fceda2cce1e2c6b9a5d 509 Gene3D G3DSA:1.10.8.60 340 409 3.7E-20 T 14-10-2018 TSH58p_11545 540007cc33658fceda2cce1e2c6b9a5d 509 SUPERFAMILY SSF48295 404 508 3.14E-39 T 14-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 TSH58p_11545 540007cc33658fceda2cce1e2c6b9a5d 509 Gene3D G3DSA:3.40.50.300 159 338 9.5E-53 T 14-10-2018 TSH58p_11545 540007cc33658fceda2cce1e2c6b9a5d 509 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 467 486 7.5E-50 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like TSH58p_11545 540007cc33658fceda2cce1e2c6b9a5d 509 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 239 253 7.5E-50 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like TSH58p_11545 540007cc33658fceda2cce1e2c6b9a5d 509 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 271 285 7.5E-50 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like TSH58p_11545 540007cc33658fceda2cce1e2c6b9a5d 509 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 207 227 7.5E-50 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like TSH58p_11545 540007cc33658fceda2cce1e2c6b9a5d 509 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 305 332 7.5E-50 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like TSH58p_11545 540007cc33658fceda2cce1e2c6b9a5d 509 SMART SM00382 206 334 1.8E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_11545 540007cc33658fceda2cce1e2c6b9a5d 509 Pfam PF11638 DnaA N-terminal domain 9 70 3.2E-20 T 14-10-2018 IPR024633 DnaA N-terminal domain TSH58p_13850 b0ba7157ff3c88eed280e89876c866f6 554 SUPERFAMILY SSF52402 259 535 7.15E-75 T 14-10-2018 TSH58p_13850 b0ba7157ff3c88eed280e89876c866f6 554 Gene3D G3DSA:3.40.50.620 268 553 3.9E-114 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_13850 b0ba7157ff3c88eed280e89876c866f6 554 SUPERFAMILY SSF56317 4 243 6.93E-63 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TSH58p_13850 b0ba7157ff3c88eed280e89876c866f6 554 Hamap MF_02090 Glutamine-dependent NAD(+) synthetase [nadE]. 5 552 28.858 T 14-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 TSH58p_13850 b0ba7157ff3c88eed280e89876c866f6 554 TIGRFAM TIGR00552 nadE: NAD+ synthetase 276 534 1.4E-57 T 14-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 TSH58p_13850 b0ba7157ff3c88eed280e89876c866f6 554 Gene3D G3DSA:3.60.110.10 2 254 3.7E-85 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TSH58p_13850 b0ba7157ff3c88eed280e89876c866f6 554 Pfam PF02540 NAD synthase 270 527 3.2E-70 T 14-10-2018 IPR022310 NAD/GMP synthase TSH58p_13850 b0ba7157ff3c88eed280e89876c866f6 554 Pfam PF00795 Carbon-nitrogen hydrolase 7 242 1.3E-29 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 TSH58p_13850 b0ba7157ff3c88eed280e89876c866f6 554 PIRSF PIRSF006630 2 553 1.4E-183 T 14-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 TSH58p_05805 57621f766538eb4348d1fd821787949f 437 Pfam PF03129 Anticodon binding domain 348 436 9.0E-21 T 14-10-2018 IPR004154 Anticodon-binding TSH58p_05805 57621f766538eb4348d1fd821787949f 437 SUPERFAMILY SSF55681 9 347 3.45E-94 T 14-10-2018 TSH58p_05805 57621f766538eb4348d1fd821787949f 437 SUPERFAMILY SSF52954 333 436 2.62E-31 T 14-10-2018 TSH58p_05805 57621f766538eb4348d1fd821787949f 437 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 5.6E-15 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TSH58p_05805 57621f766538eb4348d1fd821787949f 437 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 5.6E-15 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TSH58p_05805 57621f766538eb4348d1fd821787949f 437 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 5.6E-15 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TSH58p_05805 57621f766538eb4348d1fd821787949f 437 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 5.6E-15 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TSH58p_05805 57621f766538eb4348d1fd821787949f 437 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 328 8.1E-36 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_05805 57621f766538eb4348d1fd821787949f 437 Hamap MF_01570 Proline--tRNA ligase [proS]. 1 437 63.118 T 14-10-2018 IPR023716 Proline-tRNA ligase, class IIa, type 2 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 TSH58p_05805 57621f766538eb4348d1fd821787949f 437 Gene3D G3DSA:3.40.50.800 331 437 3.4E-31 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily TSH58p_05805 57621f766538eb4348d1fd821787949f 437 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 223 2.6E-102 T 14-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 TSH58p_05805 57621f766538eb4348d1fd821787949f 437 Gene3D G3DSA:3.30.930.10 1 330 7.5E-114 T 14-10-2018 TSH58p_16905 3526a5a287f576491d873b7c3c4ae0f3 608 Gene3D G3DSA:3.40.50.10490 445 593 2.6E-144 T 14-10-2018 TSH58p_16905 3526a5a287f576491d873b7c3c4ae0f3 608 Pfam PF13522 Glutamine amidotransferase domain 62 193 5.0E-23 T 14-10-2018 TSH58p_16905 3526a5a287f576491d873b7c3c4ae0f3 608 Gene3D G3DSA:3.60.20.10 2 240 5.3E-71 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_16905 3526a5a287f576491d873b7c3c4ae0f3 608 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 608 39.472 T 14-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 TSH58p_16905 3526a5a287f576491d873b7c3c4ae0f3 608 SUPERFAMILY SSF56235 2 234 6.18E-71 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_16905 3526a5a287f576491d873b7c3c4ae0f3 608 Pfam PF01380 SIS domain 461 590 4.9E-23 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TSH58p_16905 3526a5a287f576491d873b7c3c4ae0f3 608 Pfam PF01380 SIS domain 288 415 1.6E-30 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TSH58p_16905 3526a5a287f576491d873b7c3c4ae0f3 608 Gene3D G3DSA:3.40.50.10490 248 607 2.6E-144 T 14-10-2018 TSH58p_16905 3526a5a287f576491d873b7c3c4ae0f3 608 SUPERFAMILY SSF53697 246 608 3.39E-112 T 14-10-2018 TSH58p_16905 3526a5a287f576491d873b7c3c4ae0f3 608 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 608 3.2E-244 T 14-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 TSH58p_18625 6cfdbfb52d89704fe088dc926fda5005 292 SUPERFAMILY SSF52402 1 161 7.53E-11 T 14-10-2018 TSH58p_18625 6cfdbfb52d89704fe088dc926fda5005 292 Gene3D G3DSA:3.40.50.620 170 292 1.2E-11 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_18625 6cfdbfb52d89704fe088dc926fda5005 292 SUPERFAMILY SSF52402 174 290 2.09E-14 T 14-10-2018 TSH58p_18625 6cfdbfb52d89704fe088dc926fda5005 292 Gene3D G3DSA:3.40.50.620 1 161 3.3E-12 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_17780 21da099d2fd721f8edd6e38ded3281c9 242 SUPERFAMILY SSF75005 3 200 8.42E-24 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TSH58p_17780 21da099d2fd721f8edd6e38ded3281c9 242 Gene3D G3DSA:2.115.10.20 3 193 4.3E-18 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TSH58p_10150 811ce85627a0ab38f41dc154faaff17d 258 SMART SM00382 30 225 2.7E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_10150 811ce85627a0ab38f41dc154faaff17d 258 Pfam PF00005 ABC transporter 22 167 7.8E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_10150 811ce85627a0ab38f41dc154faaff17d 258 SUPERFAMILY SSF52540 1 229 1.28E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_10150 811ce85627a0ab38f41dc154faaff17d 258 Gene3D G3DSA:3.40.50.300 1 256 9.9E-77 T 14-10-2018 TSH58p_10150 811ce85627a0ab38f41dc154faaff17d 258 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_08625 5f6fec3f9352bdc827d93f5796037ef0 641 Gene3D G3DSA:3.40.50.2000 507 609 1.0E-6 T 14-10-2018 TSH58p_08625 5f6fec3f9352bdc827d93f5796037ef0 641 Pfam PF07719 Tetratricopeptide repeat 182 214 1.4E-6 T 14-10-2018 IPR013105 Tetratricopeptide repeat 2 TSH58p_08625 5f6fec3f9352bdc827d93f5796037ef0 641 Gene3D G3DSA:1.25.40.10 292 359 9.5E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_08625 5f6fec3f9352bdc827d93f5796037ef0 641 Gene3D G3DSA:1.25.40.10 141 283 3.5E-27 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_08625 5f6fec3f9352bdc827d93f5796037ef0 641 SUPERFAMILY SSF53756 371 616 3.01E-25 T 14-10-2018 TSH58p_08625 5f6fec3f9352bdc827d93f5796037ef0 641 Gene3D G3DSA:1.25.40.10 2 140 1.2E-17 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_08625 5f6fec3f9352bdc827d93f5796037ef0 641 Pfam PF13432 Tetratricopeptide repeat 221 281 0.0014 T 14-10-2018 TSH58p_08625 5f6fec3f9352bdc827d93f5796037ef0 641 Pfam PF13432 Tetratricopeptide repeat 17 65 0.017 T 14-10-2018 TSH58p_08625 5f6fec3f9352bdc827d93f5796037ef0 641 SUPERFAMILY SSF48452 8 139 1.46E-15 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_08625 5f6fec3f9352bdc827d93f5796037ef0 641 SMART SM00028 182 215 1.1E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_08625 5f6fec3f9352bdc827d93f5796037ef0 641 SMART SM00028 72 108 170.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_08625 5f6fec3f9352bdc827d93f5796037ef0 641 SMART SM00028 4 37 5.9 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_08625 5f6fec3f9352bdc827d93f5796037ef0 641 SMART SM00028 148 181 67.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_08625 5f6fec3f9352bdc827d93f5796037ef0 641 SMART SM00028 284 317 14.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_08625 5f6fec3f9352bdc827d93f5796037ef0 641 SMART SM00028 216 249 0.72 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_08625 5f6fec3f9352bdc827d93f5796037ef0 641 SUPERFAMILY SSF48452 148 346 1.08E-33 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_31905 890aaafd95209088d5b8ccf4aa9acc23 300 Gene3D G3DSA:3.20.20.370 7 296 8.3E-53 T 14-10-2018 TSH58p_31905 890aaafd95209088d5b8ccf4aa9acc23 300 Pfam PF01522 Polysaccharide deacetylase 65 173 4.8E-10 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 TSH58p_31905 890aaafd95209088d5b8ccf4aa9acc23 300 SUPERFAMILY SSF88713 4 287 1.01E-52 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TSH58p_10645 f8889a9b94dbf2321a9bf5bbea2aead6 297 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 74 1.4E-11 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TSH58p_10645 f8889a9b94dbf2321a9bf5bbea2aead6 297 SUPERFAMILY SSF51735 1 283 2.22E-40 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_10645 f8889a9b94dbf2321a9bf5bbea2aead6 297 Gene3D G3DSA:3.40.50.720 1 259 1.6E-39 T 14-10-2018 TSH58p_13020 813b841a41afcce8a40d63ce06e440c6 451 SMART SM00984 320 425 4.7E-13 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSH58p_13020 813b841a41afcce8a40d63ce06e440c6 451 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 10 419 3.3E-101 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 TSH58p_13020 813b841a41afcce8a40d63ce06e440c6 451 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 321 423 5.1E-13 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSH58p_13020 813b841a41afcce8a40d63ce06e440c6 451 Gene3D G3DSA:3.40.50.720 3 200 6.3E-58 T 14-10-2018 TSH58p_13020 813b841a41afcce8a40d63ce06e440c6 451 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 10 178 2.9E-39 T 14-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSH58p_13020 813b841a41afcce8a40d63ce06e440c6 451 SUPERFAMILY SSF51735 9 196 2.1E-37 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_13020 813b841a41afcce8a40d63ce06e440c6 451 SUPERFAMILY SSF52413 315 425 2.75E-11 T 14-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 TSH58p_13020 813b841a41afcce8a40d63ce06e440c6 451 Gene3D G3DSA:3.40.50.720 203 448 4.0E-45 T 14-10-2018 TSH58p_13020 813b841a41afcce8a40d63ce06e440c6 451 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 203 293 2.9E-21 T 14-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSH58p_13020 813b841a41afcce8a40d63ce06e440c6 451 SUPERFAMILY SSF48179 203 295 5.95E-20 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_13020 813b841a41afcce8a40d63ce06e440c6 451 PIRSF PIRSF500136 3 437 8.5E-94 T 14-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 TSH58p_13020 813b841a41afcce8a40d63ce06e440c6 451 PIRSF PIRSF000124 9 441 4.1E-63 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 TSH58p_15385 056bd058e26b07114c02d3a0a45136f0 138 Pfam PF10768 Class II flagellar assembly regulator 1 136 2.9E-40 T 14-10-2018 IPR019704 Flagellar assembly regulator FliX, class II GO:0044781 TSH58p_16160 445b3f72fc254672be5aa6158116484f 446 SUPERFAMILY SSF53383 1 446 6.6E-113 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_16160 445b3f72fc254672be5aa6158116484f 446 Gene3D G3DSA:3.90.1150.10 72 442 7.4E-156 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_16160 445b3f72fc254672be5aa6158116484f 446 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 1 445 45.566 T 14-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 TSH58p_16160 445b3f72fc254672be5aa6158116484f 446 PIRSF PIRSF006815 1 446 1.6E-167 T 14-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 TSH58p_16160 445b3f72fc254672be5aa6158116484f 446 Pfam PF02347 Glycine cleavage system P-protein 1 438 2.5E-119 T 14-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 TSH58p_16160 445b3f72fc254672be5aa6158116484f 446 Gene3D G3DSA:3.40.640.10 83 347 7.4E-156 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_21965 dad032cc41e25732b4560aa9c68e044c 224 SUPERFAMILY SSF55961 1 147 7.86E-47 T 14-10-2018 TSH58p_21965 dad032cc41e25732b4560aa9c68e044c 224 Gene3D G3DSA:3.30.530.20 1 151 9.0E-49 T 14-10-2018 IPR023393 START-like domain superfamily TSH58p_21965 dad032cc41e25732b4560aa9c68e044c 224 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 5 145 2.4E-46 T 14-10-2018 IPR010419 Carbon monoxide dehydrogenase subunit G TSH58p_26660 7e34ba1be87d34f00752a33326581fa3 312 SUPERFAMILY SSF161098 68 297 9.68E-60 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_26660 7e34ba1be87d34f00752a33326581fa3 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 304 5.1E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_26660 7e34ba1be87d34f00752a33326581fa3 312 Gene3D G3DSA:1.10.3720.10 64 309 3.6E-68 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_15865 fca5bd27bbcd67e7981848723e7dc90a 583 PIRSF PIRSF001217 1 566 3.6E-145 T 14-10-2018 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 TSH58p_15865 fca5bd27bbcd67e7981848723e7dc90a 583 Pfam PF01343 Peptidase family S49 130 261 1.8E-27 T 14-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 TSH58p_15865 fca5bd27bbcd67e7981848723e7dc90a 583 Pfam PF01343 Peptidase family S49 361 512 2.0E-45 T 14-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 TSH58p_15865 fca5bd27bbcd67e7981848723e7dc90a 583 SUPERFAMILY SSF52096 283 498 1.65E-41 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_15865 fca5bd27bbcd67e7981848723e7dc90a 583 SUPERFAMILY SSF52096 65 255 1.85E-19 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_15865 fca5bd27bbcd67e7981848723e7dc90a 583 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 292 510 5.4E-50 T 14-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 TSH58p_15865 fca5bd27bbcd67e7981848723e7dc90a 583 Gene3D G3DSA:3.90.226.10 283 511 2.5E-138 T 14-10-2018 TSH58p_15865 fca5bd27bbcd67e7981848723e7dc90a 583 TIGRFAM TIGR00705 SppA_67K: signal peptide peptidase SppA, 67K type 37 550 5.3E-98 T 14-10-2018 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 TSH58p_15865 fca5bd27bbcd67e7981848723e7dc90a 583 Gene3D G3DSA:3.90.226.10 67 282 2.5E-138 T 14-10-2018 TSH58p_15865 fca5bd27bbcd67e7981848723e7dc90a 583 Gene3D G3DSA:3.40.1750.10 162 468 2.5E-138 T 14-10-2018 TSH58p_26885 927ba777a5eea46bfe0599db7609d8a8 306 PIRSF PIRSF001365 2 304 1.6E-75 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_26885 927ba777a5eea46bfe0599db7609d8a8 306 SUPERFAMILY SSF51569 4 292 4.08E-80 T 14-10-2018 TSH58p_26885 927ba777a5eea46bfe0599db7609d8a8 306 Gene3D G3DSA:3.20.20.70 4 298 2.1E-84 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_26885 927ba777a5eea46bfe0599db7609d8a8 306 PRINTS PR00146 Dihydrodipicolinate synthase signature 76 94 2.3E-15 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_26885 927ba777a5eea46bfe0599db7609d8a8 306 PRINTS PR00146 Dihydrodipicolinate synthase signature 133 150 2.3E-15 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_26885 927ba777a5eea46bfe0599db7609d8a8 306 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 2.3E-15 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_26885 927ba777a5eea46bfe0599db7609d8a8 306 PRINTS PR00146 Dihydrodipicolinate synthase signature 108 124 2.3E-15 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_26885 927ba777a5eea46bfe0599db7609d8a8 306 Pfam PF00701 Dihydrodipicolinate synthetase family 7 290 3.6E-59 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_26885 927ba777a5eea46bfe0599db7609d8a8 306 SMART SM01130 6 294 1.6E-84 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_30090 ad3dad363be4b4209fc22a06c1be7fe3 327 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 45 111 2.6E-11 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 TSH58p_30090 ad3dad363be4b4209fc22a06c1be7fe3 327 Pfam PF00589 Phage integrase family 138 311 4.1E-21 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TSH58p_30090 ad3dad363be4b4209fc22a06c1be7fe3 327 SUPERFAMILY SSF56349 35 312 1.68E-41 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TSH58p_30090 ad3dad363be4b4209fc22a06c1be7fe3 327 Gene3D G3DSA:1.10.150.130 30 131 6.6E-14 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal TSH58p_30090 ad3dad363be4b4209fc22a06c1be7fe3 327 Gene3D G3DSA:1.10.443.10 135 315 3.0E-30 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TSH58p_19920 2c9f1bf35eb0b78a90597149caa4273a 152 SUPERFAMILY SSF54292 2 77 5.77E-27 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TSH58p_19920 2c9f1bf35eb0b78a90597149caa4273a 152 Gene3D G3DSA:1.10.150.120 77 152 2.9E-24 T 14-10-2018 TSH58p_19920 2c9f1bf35eb0b78a90597149caa4273a 152 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 TSH58p_19920 2c9f1bf35eb0b78a90597149caa4273a 152 SUPERFAMILY SSF47741 72 150 8.37E-30 T 14-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily TSH58p_19920 2c9f1bf35eb0b78a90597149caa4273a 152 Gene3D G3DSA:3.10.20.30 1 75 1.7E-28 T 14-10-2018 IPR012675 Beta-grasp domain superfamily TSH58p_19920 2c9f1bf35eb0b78a90597149caa4273a 152 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 62 7.0E-8 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 TSH58p_19920 2c9f1bf35eb0b78a90597149caa4273a 152 Pfam PF01799 [2Fe-2S] binding domain 72 144 9.1E-25 T 14-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 TSH58p_26700 c55d7285295d119066454c95ae208536 353 Gene3D G3DSA:1.10.260.40 14 80 3.9E-19 T 14-10-2018 TSH58p_26700 c55d7285295d119066454c95ae208536 353 Pfam PF00356 Bacterial regulatory proteins, lacI family 24 69 1.3E-13 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TSH58p_26700 c55d7285295d119066454c95ae208536 353 ProSitePatterns PS00356 LacI-type HTH domain signature. 25 43 - T 14-10-2018 TSH58p_26700 c55d7285295d119066454c95ae208536 353 Pfam PF13377 Periplasmic binding protein-like domain 189 352 3.6E-30 T 14-10-2018 TSH58p_26700 c55d7285295d119066454c95ae208536 353 SUPERFAMILY SSF53822 79 339 4.93E-50 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_26700 c55d7285295d119066454c95ae208536 353 SUPERFAMILY SSF47413 22 80 5.63E-16 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_26700 c55d7285295d119066454c95ae208536 353 Gene3D G3DSA:3.40.50.2300 84 329 4.7E-60 T 14-10-2018 TSH58p_26700 c55d7285295d119066454c95ae208536 353 Gene3D G3DSA:3.40.50.2300 180 313 4.7E-60 T 14-10-2018 TSH58p_26700 c55d7285295d119066454c95ae208536 353 SMART SM00354 22 92 2.4E-18 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TSH58p_15270 fc78db45449099f3b55dabc4cf9b861f 215 Pfam PF05191 Adenylate kinase, active site lid 127 163 9.8E-13 T 14-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 TSH58p_15270 fc78db45449099f3b55dabc4cf9b861f 215 SUPERFAMILY SSF52540 1 213 1.96E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_15270 fc78db45449099f3b55dabc4cf9b861f 215 Hamap MF_00235 Adenylate kinase [adk]. 1 214 49.363 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TSH58p_15270 fc78db45449099f3b55dabc4cf9b861f 215 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 14-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TSH58p_15270 fc78db45449099f3b55dabc4cf9b861f 215 Gene3D G3DSA:3.40.50.300 1 215 2.0E-77 T 14-10-2018 TSH58p_15270 fc78db45449099f3b55dabc4cf9b861f 215 TIGRFAM TIGR01351 adk: adenylate kinase 2 213 3.6E-79 T 14-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 TSH58p_15270 fc78db45449099f3b55dabc4cf9b861f 215 PRINTS PR00094 Adenylate kinase signature 161 176 9.8E-36 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TSH58p_15270 fc78db45449099f3b55dabc4cf9b861f 215 PRINTS PR00094 Adenylate kinase signature 178 192 9.8E-36 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TSH58p_15270 fc78db45449099f3b55dabc4cf9b861f 215 PRINTS PR00094 Adenylate kinase signature 4 17 9.8E-36 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TSH58p_15270 fc78db45449099f3b55dabc4cf9b861f 215 PRINTS PR00094 Adenylate kinase signature 81 97 9.8E-36 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TSH58p_15270 fc78db45449099f3b55dabc4cf9b861f 215 PRINTS PR00094 Adenylate kinase signature 32 46 9.8E-36 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TSH58p_15270 fc78db45449099f3b55dabc4cf9b861f 215 Pfam PF00406 Adenylate kinase 5 191 5.9E-56 T 14-10-2018 TSH58p_01540 78f70b7aa7f3f49f9b7ab6d6403292fa 339 PIRSF PIRSF006470 3 333 1.1E-109 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 TSH58p_01540 78f70b7aa7f3f49f9b7ab6d6403292fa 339 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 37 288 1.4E-80 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 TSH58p_01540 78f70b7aa7f3f49f9b7ab6d6403292fa 339 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 36 316 1.5E-88 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 TSH58p_01540 78f70b7aa7f3f49f9b7ab6d6403292fa 339 Gene3D G3DSA:3.40.190.170 27 338 1.2E-101 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily TSH58p_19700 af4d5ecffbe32108f2434c366a9110b7 374 Pfam PF08442 ATP-grasp domain 3 192 4.2E-52 T 14-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSH58p_19700 af4d5ecffbe32108f2434c366a9110b7 374 Gene3D G3DSA:3.30.470.20 1 220 4.1E-71 T 14-10-2018 TSH58p_19700 af4d5ecffbe32108f2434c366a9110b7 374 Pfam PF00549 CoA-ligase 253 349 1.1E-10 T 14-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSH58p_19700 af4d5ecffbe32108f2434c366a9110b7 374 Gene3D G3DSA:3.30.1490.20 21 95 4.1E-71 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSH58p_19700 af4d5ecffbe32108f2434c366a9110b7 374 PIRSF PIRSF001554 1 374 2.7E-113 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSH58p_19700 af4d5ecffbe32108f2434c366a9110b7 374 SUPERFAMILY SSF56059 1 222 2.29E-59 T 14-10-2018 TSH58p_19700 af4d5ecffbe32108f2434c366a9110b7 374 Gene3D G3DSA:3.40.50.261 230 374 6.7E-39 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSH58p_19700 af4d5ecffbe32108f2434c366a9110b7 374 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 247 272 - T 14-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSH58p_19700 af4d5ecffbe32108f2434c366a9110b7 374 SUPERFAMILY SSF52210 231 373 1.96E-34 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSH58p_25405 59c23d41863722565f78510d18bb3c4f 328 SUPERFAMILY SSF56281 34 325 4.97E-47 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_25405 59c23d41863722565f78510d18bb3c4f 328 Pfam PF00753 Metallo-beta-lactamase superfamily 98 293 5.9E-18 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_25405 59c23d41863722565f78510d18bb3c4f 328 SMART SM00849 96 303 7.4E-18 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_25405 59c23d41863722565f78510d18bb3c4f 328 Gene3D G3DSA:3.60.15.10 41 328 1.7E-81 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_27575 089d7fa3172319d5ba31c9e1c51620d1 720 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 161 184 - T 14-10-2018 IPR025505 FHIPEP conserved site TSH58p_27575 089d7fa3172319d5ba31c9e1c51620d1 720 Gene3D G3DSA:1.10.8.540 531 619 3.2E-25 T 14-10-2018 TSH58p_27575 089d7fa3172319d5ba31c9e1c51620d1 720 Gene3D G3DSA:1.10.490.80 622 720 2.9E-15 T 14-10-2018 TSH58p_27575 089d7fa3172319d5ba31c9e1c51620d1 720 Pfam PF00771 FHIPEP family 45 712 1.4E-252 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 TSH58p_27575 089d7fa3172319d5ba31c9e1c51620d1 720 Gene3D G3DSA:3.40.30.60 385 530 1.3E-48 T 14-10-2018 TSH58p_27575 089d7fa3172319d5ba31c9e1c51620d1 720 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 205 222 1.1E-53 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 TSH58p_27575 089d7fa3172319d5ba31c9e1c51620d1 720 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 52 65 1.1E-53 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 TSH58p_27575 089d7fa3172319d5ba31c9e1c51620d1 720 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 89 108 1.1E-53 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 TSH58p_27575 089d7fa3172319d5ba31c9e1c51620d1 720 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 256 270 1.1E-53 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 TSH58p_27575 089d7fa3172319d5ba31c9e1c51620d1 720 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 156 172 1.1E-53 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 TSH58p_27575 089d7fa3172319d5ba31c9e1c51620d1 720 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 175 193 1.1E-53 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 TSH58p_27575 089d7fa3172319d5ba31c9e1c51620d1 720 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 35 720 5.4E-263 T 14-10-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 TSH58p_27575 089d7fa3172319d5ba31c9e1c51620d1 720 PIRSF PIRSF005419 19 720 8.1E-228 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 TSH58p_07065 6d61c9cec7a2623faec4b3af74481581 419 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 153 263 1.9E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_07065 6d61c9cec7a2623faec4b3af74481581 419 Gene3D G3DSA:3.30.565.10 115 266 1.5E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_07065 6d61c9cec7a2623faec4b3af74481581 419 Pfam PF00072 Response regulator receiver domain 303 413 3.3E-13 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_07065 6d61c9cec7a2623faec4b3af74481581 419 SUPERFAMILY SSF55874 98 264 2.1E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_07065 6d61c9cec7a2623faec4b3af74481581 419 Gene3D G3DSA:1.10.287.130 7 106 3.4E-16 T 14-10-2018 TSH58p_07065 6d61c9cec7a2623faec4b3af74481581 419 PRINTS PR00344 Bacterial sensor protein C-terminal signature 208 218 3.9E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_07065 6d61c9cec7a2623faec4b3af74481581 419 PRINTS PR00344 Bacterial sensor protein C-terminal signature 190 204 3.9E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_07065 6d61c9cec7a2623faec4b3af74481581 419 PRINTS PR00344 Bacterial sensor protein C-terminal signature 249 262 3.9E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_07065 6d61c9cec7a2623faec4b3af74481581 419 PRINTS PR00344 Bacterial sensor protein C-terminal signature 225 243 3.9E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_07065 6d61c9cec7a2623faec4b3af74481581 419 Pfam PF00512 His Kinase A (phospho-acceptor) domain 42 108 1.9E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_07065 6d61c9cec7a2623faec4b3af74481581 419 SMART SM00387 152 265 2.7E-27 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_07065 6d61c9cec7a2623faec4b3af74481581 419 SMART SM00448 301 413 9.2E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_07065 6d61c9cec7a2623faec4b3af74481581 419 SMART SM00388 42 108 9.3E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_07065 6d61c9cec7a2623faec4b3af74481581 419 SUPERFAMILY SSF47384 28 108 2.94E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_07065 6d61c9cec7a2623faec4b3af74481581 419 SUPERFAMILY SSF52172 298 418 2.13E-24 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_07065 6d61c9cec7a2623faec4b3af74481581 419 Gene3D G3DSA:3.40.50.2300 297 419 7.3E-22 T 14-10-2018 TSH58p_10710 f4fb34da2a2d658299be87589141bd86 935 Pfam PF08335 GlnD PII-uridylyltransferase 227 365 1.1E-35 T 14-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 TSH58p_10710 f4fb34da2a2d658299be87589141bd86 935 SUPERFAMILY SSF55021 746 801 4.16E-10 T 14-10-2018 TSH58p_10710 f4fb34da2a2d658299be87589141bd86 935 SUPERFAMILY SSF81891 410 651 6.87E-24 T 14-10-2018 TSH58p_10710 f4fb34da2a2d658299be87589141bd86 935 Gene3D G3DSA:3.30.70.260 855 933 1.0E-7 T 14-10-2018 TSH58p_10710 f4fb34da2a2d658299be87589141bd86 935 SMART SM00471 504 651 7.6E-7 T 14-10-2018 IPR003607 HD/PDEase domain TSH58p_10710 f4fb34da2a2d658299be87589141bd86 935 PIRSF PIRSF006288 44 935 0.0 T 14-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 TSH58p_10710 f4fb34da2a2d658299be87589141bd86 935 Gene3D G3DSA:1.10.3090.10 404 689 3.9E-11 T 14-10-2018 TSH58p_10710 f4fb34da2a2d658299be87589141bd86 935 SUPERFAMILY SSF55021 857 927 3.12E-12 T 14-10-2018 TSH58p_10710 f4fb34da2a2d658299be87589141bd86 935 SUPERFAMILY SSF81593 247 354 2.35E-7 T 14-10-2018 TSH58p_10710 f4fb34da2a2d658299be87589141bd86 935 SUPERFAMILY SSF81301 29 221 5.45E-34 T 14-10-2018 TSH58p_10710 f4fb34da2a2d658299be87589141bd86 935 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 69 930 1.5E-292 T 14-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 TSH58p_10710 f4fb34da2a2d658299be87589141bd86 935 Pfam PF01966 HD domain 509 639 4.1E-10 T 14-10-2018 IPR006674 HD domain TSH58p_10710 f4fb34da2a2d658299be87589141bd86 935 Pfam PF01909 Nucleotidyltransferase domain 119 155 1.5E-4 T 14-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TSH58p_10710 f4fb34da2a2d658299be87589141bd86 935 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 54 935 292.679 T 14-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 SMART SM00388 943 1011 2.8E-22 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 SMART SM00387 1058 1183 1.5E-36 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 SUPERFAMILY SSF52172 1514 1637 2.56E-36 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 SUPERFAMILY SSF58104 305 620 8.89E-18 T 14-10-2018 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 SUPERFAMILY SSF55874 1000 1181 1.28E-42 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 Gene3D G3DSA:3.40.50.2300 1389 1493 1.2E-6 T 14-10-2018 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 SUPERFAMILY SSF52172 1392 1453 9.25E-7 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 SMART SM00304 469 521 5.4E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 SMART SM00304 561 613 2.6E-4 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 SMART SM00304 5 56 120.0 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 SMART SM00304 193 245 3.4E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 SMART SM00304 653 705 4.4E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 SMART SM00304 285 337 5.9E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 SMART SM00304 377 429 7.2E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 SMART SM00304 96 153 0.0018 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 Pfam PF00072 Response regulator receiver domain 1236 1344 1.3E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 Pfam PF00072 Response regulator receiver domain 1518 1629 1.2E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 Pfam PF00512 His Kinase A (phospho-acceptor) domain 944 1011 8.3E-18 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 SMART SM00448 1515 1629 1.5E-34 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 SMART SM00448 1234 1344 1.7E-18 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1058 1181 4.7E-27 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 SUPERFAMILY SSF52172 1233 1359 1.71E-24 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 SUPERFAMILY SSF47384 928 1011 3.53E-19 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 SUPERFAMILY SSF158472 197 242 2.88E-5 T 14-10-2018 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 Gene3D G3DSA:3.30.450.40 717 869 3.4E-18 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 SMART SM00065 729 875 3.7E-9 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 Gene3D G3DSA:3.40.50.12740 1514 1650 1.5E-38 T 14-10-2018 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 Gene3D G3DSA:3.40.50.12740 1235 1376 1.5E-26 T 14-10-2018 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 Pfam PF13185 GAF domain 728 865 7.2E-20 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 Gene3D G3DSA:3.30.565.10 1010 1184 1.4E-47 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 Gene3D G3DSA:1.10.8.500 378 435 2.2E-7 T 14-10-2018 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 Gene3D G3DSA:1.10.8.500 195 251 4.8E-7 T 14-10-2018 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 Gene3D G3DSA:1.10.8.500 268 343 1.9E-7 T 14-10-2018 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 Gene3D G3DSA:1.10.8.500 653 716 3.6E-6 T 14-10-2018 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 Gene3D G3DSA:1.10.8.500 452 527 1.0E-7 T 14-10-2018 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1108 1122 5.3E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1167 1180 5.3E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1126 1136 5.3E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1143 1161 5.3E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 Gene3D G3DSA:1.10.287.130 910 1009 9.6E-25 T 14-10-2018 TSH58p_00825 4239a28f592a5e0980d473d4e6deba2a 1650 SUPERFAMILY SSF55781 692 865 1.02E-28 T 14-10-2018 TSH58p_13625 d3b05dde3f9e81c7adceaeda8dc78a1b 237 Pfam PF04340 Protein of unknown function, DUF484 12 232 9.8E-36 T 14-10-2018 IPR007435 Protein of unknown function DUF484 TSH58p_13625 d3b05dde3f9e81c7adceaeda8dc78a1b 237 Gene3D G3DSA:3.30.450.40 52 233 8.0E-32 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_29695 66fe5449520f519516d4d79fc3486d6f 256 ProSitePatterns PS00761 Signal peptidases I signature 3. 192 205 - T 14-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 TSH58p_29695 66fe5449520f519516d4d79fc3486d6f 256 SUPERFAMILY SSF51306 37 254 2.04E-63 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily TSH58p_29695 66fe5449520f519516d4d79fc3486d6f 256 Gene3D G3DSA:2.170.230.10 120 186 1.9E-59 T 14-10-2018 TSH58p_29695 66fe5449520f519516d4d79fc3486d6f 256 ProSitePatterns PS00501 Signal peptidases I serine active site. 48 55 - T 14-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 TSH58p_29695 66fe5449520f519516d4d79fc3486d6f 256 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 23 230 9.7E-49 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TSH58p_29695 66fe5449520f519516d4d79fc3486d6f 256 Gene3D G3DSA:2.10.109.10 37 229 1.9E-59 T 14-10-2018 TSH58p_29695 66fe5449520f519516d4d79fc3486d6f 256 ProSitePatterns PS00760 Signal peptidases I lysine active site. 111 123 - T 14-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 TSH58p_29695 66fe5449520f519516d4d79fc3486d6f 256 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 187 206 4.1E-24 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TSH58p_29695 66fe5449520f519516d4d79fc3486d6f 256 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 109 121 4.1E-24 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TSH58p_29695 66fe5449520f519516d4d79fc3486d6f 256 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 39 55 4.1E-24 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TSH58p_29695 66fe5449520f519516d4d79fc3486d6f 256 Pfam PF00717 Peptidase S24-like 46 132 1.3E-20 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C TSH58p_04205 eb915791816145a3b9c03640f28295eb 796 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 21 141 2.1E-30 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead TSH58p_04205 eb915791816145a3b9c03640f28295eb 796 SUPERFAMILY SSF54665 5 163 8.24E-49 T 14-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily TSH58p_04205 eb915791816145a3b9c03640f28295eb 796 Gene3D G3DSA:3.30.365.10 435 784 6.4E-142 T 14-10-2018 TSH58p_04205 eb915791816145a3b9c03640f28295eb 796 Gene3D G3DSA:3.90.1170.50 1 141 1.2E-49 T 14-10-2018 TSH58p_04205 eb915791816145a3b9c03640f28295eb 796 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 157 723 4.9E-181 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 TSH58p_04205 eb915791816145a3b9c03640f28295eb 796 SUPERFAMILY SSF56003 133 788 1.7E-211 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 TSH58p_04205 eb915791816145a3b9c03640f28295eb 796 Gene3D G3DSA:3.30.365.10 198 295 3.6E-67 T 14-10-2018 TSH58p_04205 eb915791816145a3b9c03640f28295eb 796 Gene3D G3DSA:3.30.365.10 155 372 3.6E-67 T 14-10-2018 TSH58p_04205 eb915791816145a3b9c03640f28295eb 796 Gene3D G3DSA:3.30.365.10 468 637 6.4E-142 T 14-10-2018 TSH58p_04205 eb915791816145a3b9c03640f28295eb 796 SMART SM01008 21 141 2.0E-58 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead TSH58p_13920 0645eecb553b939330175cfd910fe0a7 328 Pfam PF09084 NMT1/THI5 like 55 251 6.7E-11 T 14-10-2018 IPR015168 SsuA/THI5-like TSH58p_13920 0645eecb553b939330175cfd910fe0a7 328 Gene3D G3DSA:3.40.190.10 154 316 5.1E-12 T 14-10-2018 TSH58p_13920 0645eecb553b939330175cfd910fe0a7 328 SUPERFAMILY SSF53850 28 254 1.99E-24 T 14-10-2018 TSH58p_13920 0645eecb553b939330175cfd910fe0a7 328 Gene3D G3DSA:3.40.190.10 28 143 4.8E-9 T 14-10-2018 TSH58p_12810 e45b796aaf1bdd6700773758b3fcd7cf 342 Gene3D G3DSA:3.40.190.10 128 340 1.7E-134 T 14-10-2018 TSH58p_12810 e45b796aaf1bdd6700773758b3fcd7cf 342 Pfam PF13343 Bacterial extracellular solute-binding protein 75 309 1.3E-28 T 14-10-2018 TSH58p_12810 e45b796aaf1bdd6700773758b3fcd7cf 342 Gene3D G3DSA:3.40.190.10 30 305 1.7E-134 T 14-10-2018 TSH58p_12810 e45b796aaf1bdd6700773758b3fcd7cf 342 PIRSF PIRSF002825 6 342 6.1E-93 T 14-10-2018 IPR026045 Ferric binding protein TSH58p_12810 e45b796aaf1bdd6700773758b3fcd7cf 342 SUPERFAMILY SSF53850 28 338 9.13E-88 T 14-10-2018 TSH58p_25540 eab49de1fab7cc39fcc26fd1ca38e27a 196 SMART SM01012 134 189 9.7E-21 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 TSH58p_25540 eab49de1fab7cc39fcc26fd1ca38e27a 196 PIRSF PIRSF036382 1 195 3.1E-44 T 14-10-2018 IPR008327 Signal transduction response regulator, antiterminator TSH58p_25540 eab49de1fab7cc39fcc26fd1ca38e27a 196 SUPERFAMILY SSF52172 5 189 2.7E-34 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_25540 eab49de1fab7cc39fcc26fd1ca38e27a 196 Gene3D G3DSA:1.10.10.10 137 195 8.1E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_25540 eab49de1fab7cc39fcc26fd1ca38e27a 196 Pfam PF03861 ANTAR domain 137 189 1.2E-17 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 TSH58p_10135 92b8c211db83b5fa6c17822ac3c2a9b5 160 Gene3D G3DSA:3.90.960.10 1 159 1.7E-52 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 TSH58p_10135 92b8c211db83b5fa6c17822ac3c2a9b5 160 Pfam PF04073 Aminoacyl-tRNA editing domain 37 148 8.2E-23 T 14-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 TSH58p_10135 92b8c211db83b5fa6c17822ac3c2a9b5 160 PIRSF PIRSF006181 1 160 3.8E-50 T 14-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC TSH58p_10135 92b8c211db83b5fa6c17822ac3c2a9b5 160 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 6 157 6.7E-54 T 14-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC TSH58p_10135 92b8c211db83b5fa6c17822ac3c2a9b5 160 SUPERFAMILY SSF55826 6 157 6.41E-40 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 TSH58p_02035 c7a02fcd665ef54350deb59dc92d0b71 172 Pfam PF08281 Sigma-70, region 4 105 154 3.4E-15 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_02035 c7a02fcd665ef54350deb59dc92d0b71 172 SUPERFAMILY SSF88659 97 158 1.2E-15 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSH58p_02035 c7a02fcd665ef54350deb59dc92d0b71 172 Gene3D G3DSA:1.10.10.10 97 165 4.6E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_02035 c7a02fcd665ef54350deb59dc92d0b71 172 Gene3D G3DSA:1.10.1740.10 1 67 1.3E-19 T 14-10-2018 TSH58p_02035 c7a02fcd665ef54350deb59dc92d0b71 172 Pfam PF04542 Sigma-70 region 2 13 74 2.7E-13 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_02035 c7a02fcd665ef54350deb59dc92d0b71 172 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 30 61 - T 14-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_02035 c7a02fcd665ef54350deb59dc92d0b71 172 SUPERFAMILY SSF88946 12 84 3.26E-17 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_02035 c7a02fcd665ef54350deb59dc92d0b71 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 157 1.0E-21 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TSH58p_10980 be1e30351e085f83d08a60b1d3faf627 856 Pfam PF09334 tRNA synthetases class I (M) 36 170 1.2E-18 T 14-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_10980 be1e30351e085f83d08a60b1d3faf627 856 PRINTS PR00985 Leucyl-tRNA synthetase signature 184 197 1.4E-45 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TSH58p_10980 be1e30351e085f83d08a60b1d3faf627 856 PRINTS PR00985 Leucyl-tRNA synthetase signature 528 550 1.4E-45 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TSH58p_10980 be1e30351e085f83d08a60b1d3faf627 856 PRINTS PR00985 Leucyl-tRNA synthetase signature 561 571 1.4E-45 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TSH58p_10980 be1e30351e085f83d08a60b1d3faf627 856 PRINTS PR00985 Leucyl-tRNA synthetase signature 489 507 1.4E-45 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TSH58p_10980 be1e30351e085f83d08a60b1d3faf627 856 PRINTS PR00985 Leucyl-tRNA synthetase signature 126 143 1.4E-45 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TSH58p_10980 be1e30351e085f83d08a60b1d3faf627 856 PRINTS PR00985 Leucyl-tRNA synthetase signature 152 168 1.4E-45 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TSH58p_10980 be1e30351e085f83d08a60b1d3faf627 856 PRINTS PR00985 Leucyl-tRNA synthetase signature 214 233 1.4E-45 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TSH58p_10980 be1e30351e085f83d08a60b1d3faf627 856 Gene3D G3DSA:3.90.740.10 226 416 0.0 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TSH58p_10980 be1e30351e085f83d08a60b1d3faf627 856 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 615 655 9.9E-9 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_10980 be1e30351e085f83d08a60b1d3faf627 856 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 420 576 8.7E-6 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_10980 be1e30351e085f83d08a60b1d3faf627 856 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 41 52 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_10980 be1e30351e085f83d08a60b1d3faf627 856 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 220 405 5.3E-68 T 14-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 TSH58p_10980 be1e30351e085f83d08a60b1d3faf627 856 Gene3D G3DSA:3.10.20.590 795 856 3.9E-23 T 14-10-2018 TSH58p_10980 be1e30351e085f83d08a60b1d3faf627 856 Pfam PF08264 Anticodon-binding domain of tRNA 703 818 7.5E-19 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TSH58p_10980 be1e30351e085f83d08a60b1d3faf627 856 Gene3D G3DSA:1.10.730.10 7 788 0.0 T 14-10-2018 TSH58p_10980 be1e30351e085f83d08a60b1d3faf627 856 Gene3D G3DSA:3.40.50.620 32 570 0.0 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_10980 be1e30351e085f83d08a60b1d3faf627 856 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 3 856 23.079 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TSH58p_10980 be1e30351e085f83d08a60b1d3faf627 856 Gene3D G3DSA:3.10.330.110 571 625 0.0 T 14-10-2018 TSH58p_10980 be1e30351e085f83d08a60b1d3faf627 856 SUPERFAMILY SSF50677 225 417 5.02E-48 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TSH58p_10980 be1e30351e085f83d08a60b1d3faf627 856 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 4 856 0.0 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TSH58p_10980 be1e30351e085f83d08a60b1d3faf627 856 SUPERFAMILY SSF47323 659 856 1.72E-36 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_10980 be1e30351e085f83d08a60b1d3faf627 856 SUPERFAMILY SSF52374 3 665 1.82E-149 T 14-10-2018 TSH58p_02615 dcf35948248486097d0df52a813cc964 94 Gene3D G3DSA:4.10.520.10 1 94 2.0E-35 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 TSH58p_02615 dcf35948248486097d0df52a813cc964 94 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 9.6E-18 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_02615 dcf35948248486097d0df52a813cc964 94 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 9.6E-18 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_02615 dcf35948248486097d0df52a813cc964 94 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 9.6E-18 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_02615 dcf35948248486097d0df52a813cc964 94 Pfam PF00216 Bacterial DNA-binding protein 1 90 1.7E-33 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_02615 dcf35948248486097d0df52a813cc964 94 SUPERFAMILY SSF47729 1 91 1.12E-32 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 TSH58p_02615 dcf35948248486097d0df52a813cc964 94 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 14-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 TSH58p_02615 dcf35948248486097d0df52a813cc964 94 SMART SM00411 1 90 6.3E-44 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_02675 dcf35948248486097d0df52a813cc964 94 Gene3D G3DSA:4.10.520.10 1 94 2.0E-35 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 TSH58p_02675 dcf35948248486097d0df52a813cc964 94 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 9.6E-18 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_02675 dcf35948248486097d0df52a813cc964 94 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 9.6E-18 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_02675 dcf35948248486097d0df52a813cc964 94 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 9.6E-18 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_02675 dcf35948248486097d0df52a813cc964 94 Pfam PF00216 Bacterial DNA-binding protein 1 90 1.7E-33 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_02675 dcf35948248486097d0df52a813cc964 94 SUPERFAMILY SSF47729 1 91 1.12E-32 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 TSH58p_02675 dcf35948248486097d0df52a813cc964 94 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 14-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 TSH58p_02675 dcf35948248486097d0df52a813cc964 94 SMART SM00411 1 90 6.3E-44 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_31010 05b599e6577ca10c05895a91a4b1c924 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 70 6.1E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_31010 05b599e6577ca10c05895a91a4b1c924 223 Pfam PF07729 FCD domain 82 203 8.9E-24 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_31010 05b599e6577ca10c05895a91a4b1c924 223 SUPERFAMILY SSF46785 7 98 5.35E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_31010 05b599e6577ca10c05895a91a4b1c924 223 Gene3D G3DSA:1.20.120.530 74 208 3.6E-25 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_31010 05b599e6577ca10c05895a91a4b1c924 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 30 44 1.3E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_31010 05b599e6577ca10c05895a91a4b1c924 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 60 1.3E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_31010 05b599e6577ca10c05895a91a4b1c924 223 Gene3D G3DSA:1.10.10.10 1 71 1.4E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_31010 05b599e6577ca10c05895a91a4b1c924 223 SUPERFAMILY SSF48008 77 209 3.66E-22 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_31010 05b599e6577ca10c05895a91a4b1c924 223 SMART SM00345 12 70 4.3E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_31010 05b599e6577ca10c05895a91a4b1c924 223 SMART SM00895 80 204 8.8E-19 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_07540 b18ae7787682fe14d26fa4a85caa4f59 627 SMART SM00065 29 181 7.9E-31 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_07540 b18ae7787682fe14d26fa4a85caa4f59 627 Pfam PF02954 Bacterial regulatory protein, Fis family 588 620 8.6E-10 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_07540 b18ae7787682fe14d26fa4a85caa4f59 627 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 417 426 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site TSH58p_07540 b18ae7787682fe14d26fa4a85caa4f59 627 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 586 603 5.8E-10 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_07540 b18ae7787682fe14d26fa4a85caa4f59 627 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 603 623 5.8E-10 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_07540 b18ae7787682fe14d26fa4a85caa4f59 627 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 291 306 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 TSH58p_07540 b18ae7787682fe14d26fa4a85caa4f59 627 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 229 242 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 TSH58p_07540 b18ae7787682fe14d26fa4a85caa4f59 627 Pfam PF00158 Sigma-54 interaction domain 206 372 1.2E-72 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 TSH58p_07540 b18ae7787682fe14d26fa4a85caa4f59 627 Pfam PF13185 GAF domain 28 171 4.3E-15 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_07540 b18ae7787682fe14d26fa4a85caa4f59 627 TIGRFAM TIGR01817 nifA: Nif-specific regulatory protein 12 462 8.0E-181 T 14-10-2018 IPR010113 Nif-specific regulatory protein GO:0003700|GO:0006355|GO:0009399 TSH58p_07540 b18ae7787682fe14d26fa4a85caa4f59 627 Gene3D G3DSA:1.10.10.60 575 627 4.3E-9 T 14-10-2018 TSH58p_07540 b18ae7787682fe14d26fa4a85caa4f59 627 Gene3D G3DSA:1.10.8.60 377 450 3.2E-21 T 14-10-2018 TSH58p_07540 b18ae7787682fe14d26fa4a85caa4f59 627 Gene3D G3DSA:3.40.50.300 192 376 4.1E-69 T 14-10-2018 TSH58p_07540 b18ae7787682fe14d26fa4a85caa4f59 627 SUPERFAMILY SSF52540 204 445 4.09E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_07540 b18ae7787682fe14d26fa4a85caa4f59 627 Gene3D G3DSA:3.30.450.40 7 183 6.9E-47 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_07540 b18ae7787682fe14d26fa4a85caa4f59 627 SUPERFAMILY SSF55781 10 170 2.84E-24 T 14-10-2018 TSH58p_07540 b18ae7787682fe14d26fa4a85caa4f59 627 SMART SM00382 225 376 1.6E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_20445 c6ee4e80ca249e86d69e79d2b6b59f5b 270 Gene3D G3DSA:3.30.1150.10 160 270 4.5E-18 T 14-10-2018 TSH58p_20445 c6ee4e80ca249e86d69e79d2b6b59f5b 270 PRINTS PR01217 Proline rich extensin signature 75 91 5.7E-10 T 14-10-2018 TSH58p_20445 c6ee4e80ca249e86d69e79d2b6b59f5b 270 PRINTS PR01217 Proline rich extensin signature 118 139 5.7E-10 T 14-10-2018 TSH58p_20445 c6ee4e80ca249e86d69e79d2b6b59f5b 270 PRINTS PR01217 Proline rich extensin signature 98 110 5.7E-10 T 14-10-2018 TSH58p_20445 c6ee4e80ca249e86d69e79d2b6b59f5b 270 PRINTS PR01217 Proline rich extensin signature 143 159 5.7E-10 T 14-10-2018 TSH58p_20445 c6ee4e80ca249e86d69e79d2b6b59f5b 270 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 204 269 2.6E-17 T 14-10-2018 IPR006260 TonB/TolA, C-terminal TSH58p_20445 c6ee4e80ca249e86d69e79d2b6b59f5b 270 SUPERFAMILY SSF74653 184 270 4.19E-15 T 14-10-2018 TSH58p_20445 c6ee4e80ca249e86d69e79d2b6b59f5b 270 Pfam PF13103 TonB C terminal 187 258 1.1E-11 T 14-10-2018 TSH58p_08015 6f6a9925207bc3410944fee0f745481f 278 Gene3D G3DSA:3.40.190.10 33 259 1.2E-93 T 14-10-2018 TSH58p_08015 6f6a9925207bc3410944fee0f745481f 278 Pfam PF12849 PBP superfamily domain 32 253 6.5E-30 T 14-10-2018 IPR024370 PBP domain TSH58p_08015 6f6a9925207bc3410944fee0f745481f 278 Gene3D G3DSA:3.40.190.10 108 222 1.2E-93 T 14-10-2018 TSH58p_08015 6f6a9925207bc3410944fee0f745481f 278 SUPERFAMILY SSF53850 31 262 5.93E-35 T 14-10-2018 TSH58p_18805 c2639c0080c6536c105604238b665482 556 ProSitePatterns PS00455 Putative AMP-binding domain signature. 193 204 - T 14-10-2018 IPR020845 AMP-binding, conserved site TSH58p_18805 c2639c0080c6536c105604238b665482 556 Gene3D G3DSA:3.40.50.12780 16 445 4.5E-112 T 14-10-2018 TSH58p_18805 c2639c0080c6536c105604238b665482 556 Pfam PF13193 AMP-binding enzyme C-terminal domain 459 534 1.8E-23 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSH58p_18805 c2639c0080c6536c105604238b665482 556 Pfam PF00501 AMP-binding enzyme 33 450 1.5E-95 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_18805 c2639c0080c6536c105604238b665482 556 Gene3D G3DSA:3.30.300.310 446 549 3.3E-35 T 14-10-2018 TSH58p_18805 c2639c0080c6536c105604238b665482 556 SUPERFAMILY SSF56801 22 546 9.29E-146 T 14-10-2018 TSH58p_28835 a7ef61e491df6e6d2ed763b2b18c9954 758 Gene3D G3DSA:3.30.365.10 449 611 1.6E-110 T 14-10-2018 TSH58p_28835 a7ef61e491df6e6d2ed763b2b18c9954 758 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 32 145 5.5E-23 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead TSH58p_28835 a7ef61e491df6e6d2ed763b2b18c9954 758 Gene3D G3DSA:3.30.365.10 30 293 4.6E-65 T 14-10-2018 TSH58p_28835 a7ef61e491df6e6d2ed763b2b18c9954 758 Gene3D G3DSA:3.90.1170.50 47 146 4.6E-65 T 14-10-2018 TSH58p_28835 a7ef61e491df6e6d2ed763b2b18c9954 758 SUPERFAMILY SSF54665 15 152 1.96E-38 T 14-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily TSH58p_28835 a7ef61e491df6e6d2ed763b2b18c9954 758 Gene3D G3DSA:3.30.365.10 147 351 4.6E-65 T 14-10-2018 TSH58p_28835 a7ef61e491df6e6d2ed763b2b18c9954 758 SMART SM01008 32 146 1.6E-38 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead TSH58p_28835 a7ef61e491df6e6d2ed763b2b18c9954 758 Gene3D G3DSA:3.30.365.10 376 753 1.6E-110 T 14-10-2018 TSH58p_28835 a7ef61e491df6e6d2ed763b2b18c9954 758 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 175 697 1.5E-110 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 TSH58p_28835 a7ef61e491df6e6d2ed763b2b18c9954 758 SUPERFAMILY SSF56003 169 757 2.75E-160 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 TSH58p_25035 7ab082c251c98c5be19e098d8c6a073d 549 Gene3D G3DSA:3.30.9.90 82 447 1.9E-207 T 14-10-2018 TSH58p_25035 7ab082c251c98c5be19e098d8c6a073d 549 Gene3D G3DSA:3.30.70.20 448 543 6.0E-41 T 14-10-2018 TSH58p_25035 7ab082c251c98c5be19e098d8c6a073d 549 SUPERFAMILY SSF51905 7 444 3.48E-57 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_25035 7ab082c251c98c5be19e098d8c6a073d 549 SUPERFAMILY SSF54862 447 546 7.48E-29 T 14-10-2018 TSH58p_25035 7ab082c251c98c5be19e098d8c6a073d 549 Gene3D G3DSA:3.50.50.60 10 385 1.9E-207 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_25035 7ab082c251c98c5be19e098d8c6a073d 549 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 443 545 2.0E-51 T 14-10-2018 TSH58p_25035 7ab082c251c98c5be19e098d8c6a073d 549 SUPERFAMILY SSF54373 211 307 1.49E-36 T 14-10-2018 TSH58p_25035 7ab082c251c98c5be19e098d8c6a073d 549 Pfam PF13450 NAD(P)-binding Rossmann-like domain 15 60 1.3E-6 T 14-10-2018 TSH58p_25960 c863bd29845ff21ff789da2f4fceaab4 876 Gene3D G3DSA:1.10.8.60 766 857 7.2E-29 T 14-10-2018 TSH58p_25960 c863bd29845ff21ff789da2f4fceaab4 876 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 205 336 5.9E-14 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSH58p_25960 c863bd29845ff21ff789da2f4fceaab4 876 Gene3D G3DSA:1.10.1780.10 1 152 8.2E-34 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 TSH58p_25960 c863bd29845ff21ff789da2f4fceaab4 876 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 855 0.0 T 14-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 TSH58p_25960 c863bd29845ff21ff789da2f4fceaab4 876 Pfam PF07724 AAA domain (Cdc48 subfamily) 596 760 2.1E-56 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSH58p_25960 c863bd29845ff21ff789da2f4fceaab4 876 SUPERFAMILY SSF81923 4 157 6.41E-40 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 TSH58p_25960 c863bd29845ff21ff789da2f4fceaab4 876 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 67 2.2E-12 T 14-10-2018 IPR004176 Clp, N-terminal TSH58p_25960 c863bd29845ff21ff789da2f4fceaab4 876 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 146 2.7E-12 T 14-10-2018 IPR004176 Clp, N-terminal TSH58p_25960 c863bd29845ff21ff789da2f4fceaab4 876 Gene3D G3DSA:3.40.50.300 350 544 7.8E-74 T 14-10-2018 TSH58p_25960 c863bd29845ff21ff789da2f4fceaab4 876 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 631 649 - T 14-10-2018 IPR028299 ClpA/B, conserved site 2 TSH58p_25960 c863bd29845ff21ff789da2f4fceaab4 876 SUPERFAMILY SSF52540 161 544 7.04E-100 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_25960 c863bd29845ff21ff789da2f4fceaab4 876 SMART SM00382 200 346 9.3E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_25960 c863bd29845ff21ff789da2f4fceaab4 876 SMART SM00382 597 748 3.3E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_25960 c863bd29845ff21ff789da2f4fceaab4 876 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 766 846 4.7E-28 T 14-10-2018 IPR019489 Clp ATPase, C-terminal TSH58p_25960 c863bd29845ff21ff789da2f4fceaab4 876 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 296 308 - T 14-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 TSH58p_25960 c863bd29845ff21ff789da2f4fceaab4 876 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 601 619 3.6E-42 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 TSH58p_25960 c863bd29845ff21ff789da2f4fceaab4 876 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 646 664 3.6E-42 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 TSH58p_25960 c863bd29845ff21ff789da2f4fceaab4 876 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 708 722 3.6E-42 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 TSH58p_25960 c863bd29845ff21ff789da2f4fceaab4 876 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 675 693 3.6E-42 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 TSH58p_25960 c863bd29845ff21ff789da2f4fceaab4 876 SUPERFAMILY SSF52540 546 849 1.15E-81 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_25960 c863bd29845ff21ff789da2f4fceaab4 876 Gene3D G3DSA:3.40.50.300 160 349 5.7E-75 T 14-10-2018 TSH58p_25960 c863bd29845ff21ff789da2f4fceaab4 876 SMART SM01086 766 855 2.9E-42 T 14-10-2018 IPR019489 Clp ATPase, C-terminal TSH58p_25960 c863bd29845ff21ff789da2f4fceaab4 876 Gene3D G3DSA:3.40.50.300 550 764 5.5E-88 T 14-10-2018 TSH58p_13735 57c1ca59310fd55af83cdea588fd20da 227 Gene3D G3DSA:3.40.50.1000 12 207 2.1E-47 T 14-10-2018 IPR023214 HAD superfamily TSH58p_13735 57c1ca59310fd55af83cdea588fd20da 227 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 141 190 2.5E-14 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_13735 57c1ca59310fd55af83cdea588fd20da 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 14 190 7.0E-22 T 14-10-2018 TSH58p_13735 57c1ca59310fd55af83cdea588fd20da 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 153 173 1.1E-6 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_13735 57c1ca59310fd55af83cdea588fd20da 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 11 22 1.1E-6 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_13735 57c1ca59310fd55af83cdea588fd20da 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 105 118 1.1E-6 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_13735 57c1ca59310fd55af83cdea588fd20da 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 135 151 1.1E-6 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_13735 57c1ca59310fd55af83cdea588fd20da 227 SUPERFAMILY SSF56784 11 212 2.76E-46 T 14-10-2018 IPR036412 HAD-like superfamily TSH58p_13735 57c1ca59310fd55af83cdea588fd20da 227 Gene3D G3DSA:1.10.150.240 24 92 2.1E-47 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 TSH58p_17015 dc83d79963f52d47a609177c6efb5795 1210 Gene3D G3DSA:3.40.50.300 555 794 1.3E-223 T 14-10-2018 TSH58p_17015 dc83d79963f52d47a609177c6efb5795 1210 Pfam PF03461 TRCF domain 1027 1118 4.2E-27 T 14-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 TSH58p_17015 dc83d79963f52d47a609177c6efb5795 1210 Gene3D G3DSA:3.30.2060.10 132 218 1.4E-85 T 14-10-2018 TSH58p_17015 dc83d79963f52d47a609177c6efb5795 1210 SUPERFAMILY SSF52540 537 797 1.56E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_17015 dc83d79963f52d47a609177c6efb5795 1210 SMART SM00487 613 803 2.3E-33 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSH58p_17015 dc83d79963f52d47a609177c6efb5795 1210 SUPERFAMILY SSF52540 795 1003 8.63E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_17015 dc83d79963f52d47a609177c6efb5795 1210 SMART SM00490 839 923 3.9E-20 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_17015 dc83d79963f52d47a609177c6efb5795 1210 Gene3D G3DSA:3.40.50.300 493 1001 1.3E-223 T 14-10-2018 TSH58p_17015 dc83d79963f52d47a609177c6efb5795 1210 Pfam PF02559 CarD-like/TRCF domain 495 587 2.9E-25 T 14-10-2018 IPR003711 CarD-like/TRCF domain TSH58p_17015 dc83d79963f52d47a609177c6efb5795 1210 Pfam PF00271 Helicase conserved C-terminal domain 818 922 1.0E-18 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_17015 dc83d79963f52d47a609177c6efb5795 1210 SUPERFAMILY SSF52540 362 482 5.31E-19 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_17015 dc83d79963f52d47a609177c6efb5795 1210 SMART SM01058 493 589 4.6E-42 T 14-10-2018 IPR003711 CarD-like/TRCF domain TSH58p_17015 dc83d79963f52d47a609177c6efb5795 1210 SUPERFAMILY SSF141259 485 561 1.96E-21 T 14-10-2018 IPR036101 CarD-like/TRCF domain superfamily TSH58p_17015 dc83d79963f52d47a609177c6efb5795 1210 SUPERFAMILY SSF52540 10 354 7.97E-85 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_17015 dc83d79963f52d47a609177c6efb5795 1210 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 34 1125 27.878 T 14-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 TSH58p_17015 dc83d79963f52d47a609177c6efb5795 1210 SUPERFAMILY SSF143517 1013 1163 1.44E-42 T 14-10-2018 IPR037235 TRCF-like, C-terminal domain TSH58p_17015 dc83d79963f52d47a609177c6efb5795 1210 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 150 1097 0.0 T 14-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 TSH58p_17015 dc83d79963f52d47a609177c6efb5795 1210 Gene3D G3DSA:3.90.1150.50 1020 1165 1.6E-40 T 14-10-2018 IPR037235 TRCF-like, C-terminal domain TSH58p_17015 dc83d79963f52d47a609177c6efb5795 1210 Gene3D G3DSA:3.40.50.11180 41 302 1.4E-85 T 14-10-2018 TSH58p_17015 dc83d79963f52d47a609177c6efb5795 1210 SMART SM00982 1024 1124 9.5E-44 T 14-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 TSH58p_17015 dc83d79963f52d47a609177c6efb5795 1210 Pfam PF00270 DEAD/DEAH box helicase 618 779 4.3E-16 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TSH58p_17015 dc83d79963f52d47a609177c6efb5795 1210 Gene3D G3DSA:2.30.30.840 497 554 1.3E-223 T 14-10-2018 TSH58p_21225 94b45e1ed672a390cbcf563a1645afbf 236 SUPERFAMILY SSF55120 9 231 3.68E-59 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSH58p_21225 94b45e1ed672a390cbcf563a1645afbf 236 Pfam PF00849 RNA pseudouridylate synthase 23 172 1.2E-29 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSH58p_21225 94b45e1ed672a390cbcf563a1645afbf 236 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 63 77 - T 14-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSH58p_21225 94b45e1ed672a390cbcf563a1645afbf 236 Gene3D G3DSA:3.30.2350.10 15 229 1.6E-56 T 14-10-2018 TSH58p_15800 df72fa880e820d2102d1648639a4e817 714 SMART SM00889 498 616 1.3E-61 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TSH58p_15800 df72fa880e820d2102d1648639a4e817 714 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 185 9.3E-31 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSH58p_15800 df72fa880e820d2102d1648639a4e817 714 Pfam PF14492 Elongation Factor G, domain II 422 495 4.3E-30 T 14-10-2018 TSH58p_15800 df72fa880e820d2102d1648639a4e817 714 Gene3D G3DSA:3.30.230.10 502 705 2.5E-86 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSH58p_15800 df72fa880e820d2102d1648639a4e817 714 SMART SM00838 618 705 9.3E-51 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like TSH58p_15800 df72fa880e820d2102d1648639a4e817 714 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.4E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_15800 df72fa880e820d2102d1648639a4e817 714 PRINTS PR00315 GTP-binding elongation factor signature 63 71 1.4E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_15800 df72fa880e820d2102d1648639a4e817 714 PRINTS PR00315 GTP-binding elongation factor signature 99 110 1.4E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_15800 df72fa880e820d2102d1648639a4e817 714 PRINTS PR00315 GTP-binding elongation factor signature 135 144 1.4E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_15800 df72fa880e820d2102d1648639a4e817 714 PRINTS PR00315 GTP-binding elongation factor signature 83 93 1.4E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_15800 df72fa880e820d2102d1648639a4e817 714 Hamap MF_00054_B Elongation factor G [fusA]. 6 709 99.095 T 14-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TSH58p_15800 df72fa880e820d2102d1648639a4e817 714 SUPERFAMILY SSF54980 621 707 1.58E-29 T 14-10-2018 IPR035647 EF-G domain III/V-like TSH58p_15800 df72fa880e820d2102d1648639a4e817 714 Gene3D G3DSA:3.30.70.240 622 692 2.5E-86 T 14-10-2018 TSH58p_15800 df72fa880e820d2102d1648639a4e817 714 Gene3D G3DSA:2.40.30.10 313 423 9.6E-38 T 14-10-2018 TSH58p_15800 df72fa880e820d2102d1648639a4e817 714 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 709 8.1E-289 T 14-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TSH58p_15800 df72fa880e820d2102d1648639a4e817 714 Pfam PF03764 Elongation factor G, domain IV 497 615 2.5E-42 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TSH58p_15800 df72fa880e820d2102d1648639a4e817 714 SUPERFAMILY SSF52540 7 300 1.13E-91 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_15800 df72fa880e820d2102d1648639a4e817 714 SUPERFAMILY SSF54980 420 498 1.29E-21 T 14-10-2018 IPR035647 EF-G domain III/V-like TSH58p_15800 df72fa880e820d2102d1648639a4e817 714 Pfam PF03144 Elongation factor Tu domain 2 342 409 2.0E-12 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TSH58p_15800 df72fa880e820d2102d1648639a4e817 714 Pfam PF00679 Elongation factor G C-terminus 618 704 1.5E-28 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like TSH58p_15800 df72fa880e820d2102d1648639a4e817 714 Gene3D G3DSA:3.30.70.870 424 501 3.0E-30 T 14-10-2018 TSH58p_15800 df72fa880e820d2102d1648639a4e817 714 SUPERFAMILY SSF54211 497 617 4.3E-42 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSH58p_15800 df72fa880e820d2102d1648639a4e817 714 SUPERFAMILY SSF50447 284 422 2.52E-29 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSH58p_15800 df72fa880e820d2102d1648639a4e817 714 Pfam PF00009 Elongation factor Tu GTP binding domain 9 300 6.9E-63 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_15800 df72fa880e820d2102d1648639a4e817 714 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 56 71 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site TSH58p_15800 df72fa880e820d2102d1648639a4e817 714 Gene3D G3DSA:3.40.50.300 2 312 3.3E-101 T 14-10-2018 TSH58p_19985 fd669d517e8c6448c0f564f58d69c72f 184 SMART SM00855 4 146 4.1E-16 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TSH58p_19985 fd669d517e8c6448c0f564f58d69c72f 184 SUPERFAMILY SSF53254 3 168 2.36E-40 T 14-10-2018 IPR029033 Histidine phosphatase superfamily TSH58p_19985 fd669d517e8c6448c0f564f58d69c72f 184 PIRSF PIRSF000709 2 74 1.8E-4 T 14-10-2018 TSH58p_19985 fd669d517e8c6448c0f564f58d69c72f 184 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 160 2.2E-34 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TSH58p_19985 fd669d517e8c6448c0f564f58d69c72f 184 Gene3D G3DSA:3.40.50.1240 1 172 6.3E-37 T 14-10-2018 IPR029033 Histidine phosphatase superfamily TSH58p_04920 217b3c82fbabd053dc894f723df870c3 283 SUPERFAMILY SSF53448 4 133 9.64E-17 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_04920 217b3c82fbabd053dc894f723df870c3 283 Gene3D G3DSA:3.90.550.10 1 161 4.0E-18 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_04920 217b3c82fbabd053dc894f723df870c3 283 Pfam PF00535 Glycosyl transferase family 2 5 105 4.3E-10 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_22015 09b40ab95d1a30004dc562c7b430fbae 320 Pfam PF00892 EamA-like transporter family 169 299 7.2E-11 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_22015 09b40ab95d1a30004dc562c7b430fbae 320 Pfam PF00892 EamA-like transporter family 26 159 5.6E-13 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_22015 09b40ab95d1a30004dc562c7b430fbae 320 SUPERFAMILY SSF103481 203 305 1.44E-13 T 14-10-2018 TSH58p_22015 09b40ab95d1a30004dc562c7b430fbae 320 SUPERFAMILY SSF103481 61 163 9.15E-12 T 14-10-2018 TSH58p_32600 d104121661de672ac42fb10200deba95 408 Pfam PF03466 LysR substrate binding domain 193 397 6.9E-30 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_32600 d104121661de672ac42fb10200deba95 408 SUPERFAMILY SSF46785 4 82 4.91E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_32600 d104121661de672ac42fb10200deba95 408 SUPERFAMILY SSF46785 103 214 1.4E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_32600 d104121661de672ac42fb10200deba95 408 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 5.9E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_32600 d104121661de672ac42fb10200deba95 408 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 110 166 9.6E-15 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_32600 d104121661de672ac42fb10200deba95 408 Gene3D G3DSA:1.10.10.10 105 192 7.0E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_32600 d104121661de672ac42fb10200deba95 408 SUPERFAMILY SSF53850 195 401 2.24E-37 T 14-10-2018 TSH58p_32600 d104121661de672ac42fb10200deba95 408 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 9.7E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_32600 d104121661de672ac42fb10200deba95 408 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 9.7E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_32600 d104121661de672ac42fb10200deba95 408 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 9.7E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_32600 d104121661de672ac42fb10200deba95 408 Gene3D G3DSA:3.40.190.10 271 370 2.5E-49 T 14-10-2018 TSH58p_32600 d104121661de672ac42fb10200deba95 408 Gene3D G3DSA:3.40.190.10 197 384 2.5E-49 T 14-10-2018 TSH58p_32600 d104121661de672ac42fb10200deba95 408 Gene3D G3DSA:1.10.10.10 5 89 3.5E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_03365 5c660c9d58260186cca85ce59ff61dc9 321 Gene3D G3DSA:3.40.190.10 125 247 1.1E-94 T 14-10-2018 TSH58p_03365 5c660c9d58260186cca85ce59ff61dc9 321 Gene3D G3DSA:3.40.190.150 30 311 1.1E-94 T 14-10-2018 TSH58p_03365 5c660c9d58260186cca85ce59ff61dc9 321 SUPERFAMILY SSF53850 113 285 5.16E-12 T 14-10-2018 TSH58p_03365 5c660c9d58260186cca85ce59ff61dc9 321 PIRSF PIRSF017082 1 321 3.1E-110 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 TSH58p_03365 5c660c9d58260186cca85ce59ff61dc9 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 318 1.2E-67 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 TSH58p_03175 36338c5e4ca900ffee7fb2163eb923a9 241 SMART SM00382 35 215 2.3E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_03175 36338c5e4ca900ffee7fb2163eb923a9 241 Gene3D G3DSA:3.40.50.300 6 239 1.0E-58 T 14-10-2018 TSH58p_03175 36338c5e4ca900ffee7fb2163eb923a9 241 Pfam PF00005 ABC transporter 26 166 5.8E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_03175 36338c5e4ca900ffee7fb2163eb923a9 241 SUPERFAMILY SSF52540 9 236 1.28E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_03175 36338c5e4ca900ffee7fb2163eb923a9 241 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_10460 2b1d52c58603c4391a7ed148cbf1facd 166 Hamap MF_01903 Xanthine phosphoribosyltransferase [gpt]. 7 163 42.01 T 14-10-2018 IPR023747 Xanthine-guanine phosphoribosyltransferase GO:0000310 KEGG: 00230+2.4.2.22 TSH58p_10460 2b1d52c58603c4391a7ed148cbf1facd 166 SUPERFAMILY SSF53271 9 152 1.04E-31 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like TSH58p_10460 2b1d52c58603c4391a7ed148cbf1facd 166 Gene3D G3DSA:3.40.50.2020 8 162 1.3E-41 T 14-10-2018 TSH58p_10460 2b1d52c58603c4391a7ed148cbf1facd 166 Pfam PF00156 Phosphoribosyl transferase domain 15 155 2.4E-15 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TSH58p_26775 04569052f3d3a52aaa617f0849b453bc 219 SUPERFAMILY SSF161098 13 198 8.5E-39 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_26775 04569052f3d3a52aaa617f0849b453bc 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 46 196 9.9E-13 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_26775 04569052f3d3a52aaa617f0849b453bc 219 Gene3D G3DSA:1.10.3720.10 4 215 1.2E-45 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_26775 04569052f3d3a52aaa617f0849b453bc 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 107 1.6E-24 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 TSH58p_16880 b567896f8daa0cbabc8031a71139b9c6 207 Pfam PF01810 LysE type translocator 16 203 2.4E-25 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 TSH58p_14910 963a67a45eed9b711042e70759b8f2f6 274 Pfam PF00005 ABC transporter 42 181 3.1E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_14910 963a67a45eed9b711042e70759b8f2f6 274 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_14910 963a67a45eed9b711042e70759b8f2f6 274 Gene3D G3DSA:3.40.50.300 20 242 7.1E-65 T 14-10-2018 TSH58p_14910 963a67a45eed9b711042e70759b8f2f6 274 SMART SM00382 51 232 3.1E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_14910 963a67a45eed9b711042e70759b8f2f6 274 SUPERFAMILY SSF52540 22 252 8.62E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_10875 c2ffe193ee714b5e24bc39be09b7709b 266 SUPERFAMILY SSF88713 85 247 8.34E-6 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TSH58p_32625 1ea26352d36d74fc88d199db2a5b0f9c 550 Pfam PF00664 ABC transporter transmembrane region 12 197 2.0E-11 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TSH58p_32625 1ea26352d36d74fc88d199db2a5b0f9c 550 SUPERFAMILY SSF90123 12 311 6.8E-37 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_32625 1ea26352d36d74fc88d199db2a5b0f9c 550 Gene3D G3DSA:3.40.50.300 319 549 5.4E-37 T 14-10-2018 TSH58p_32625 1ea26352d36d74fc88d199db2a5b0f9c 550 Gene3D G3DSA:1.20.1560.10 2 313 1.2E-29 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_32625 1ea26352d36d74fc88d199db2a5b0f9c 550 SUPERFAMILY SSF52540 336 545 2.47E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_32625 1ea26352d36d74fc88d199db2a5b0f9c 550 TIGRFAM TIGR01194 cyc_pep_trnsptr: cyclic peptide transporter 7 546 1.5E-214 T 14-10-2018 IPR005898 Cyclic peptide transporter GO:0005524|GO:0015833|GO:0016021|GO:1904680 TSH58p_32625 1ea26352d36d74fc88d199db2a5b0f9c 550 Pfam PF00005 ABC transporter 359 493 1.4E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_32625 1ea26352d36d74fc88d199db2a5b0f9c 550 SMART SM00382 366 550 1.0E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_26590 28e0c092715356eb8e704d9fe8136d1e 577 Gene3D G3DSA:3.40.50.300 345 571 9.7E-42 T 14-10-2018 TSH58p_26590 28e0c092715356eb8e704d9fe8136d1e 577 ProSitePatterns PS00211 ABC transporters family signature. 476 490 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_26590 28e0c092715356eb8e704d9fe8136d1e 577 SUPERFAMILY SSF90123 23 319 4.97E-11 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_26590 28e0c092715356eb8e704d9fe8136d1e 577 SUPERFAMILY SSF52540 346 554 1.17E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_26590 28e0c092715356eb8e704d9fe8136d1e 577 Pfam PF00005 ABC transporter 370 504 7.4E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_26590 28e0c092715356eb8e704d9fe8136d1e 577 Gene3D G3DSA:1.20.1560.10 133 328 5.5E-6 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_26590 28e0c092715356eb8e704d9fe8136d1e 577 SMART SM00382 376 552 1.4E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_03780 43b77490c236e7348300ebb82347e61c 562 Gene3D G3DSA:3.30.413.10 419 562 1.2E-32 T 14-10-2018 TSH58p_03780 43b77490c236e7348300ebb82347e61c 562 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 130 283 1.5E-41 T 14-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TSH58p_03780 43b77490c236e7348300ebb82347e61c 562 SUPERFAMILY SSF55124 11 137 9.98E-32 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TSH58p_03780 43b77490c236e7348300ebb82347e61c 562 Gene3D G3DSA:3.90.480.10 63 400 6.4E-79 T 14-10-2018 TSH58p_03780 43b77490c236e7348300ebb82347e61c 562 SUPERFAMILY SSF55124 263 432 2.29E-25 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TSH58p_03780 43b77490c236e7348300ebb82347e61c 562 SUPERFAMILY SSF56014 419 558 1.57E-38 T 14-10-2018 TSH58p_03780 43b77490c236e7348300ebb82347e61c 562 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 426 558 1.3E-14 T 14-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TSH58p_03780 43b77490c236e7348300ebb82347e61c 562 SUPERFAMILY SSF56014 131 285 1.44E-45 T 14-10-2018 TSH58p_03780 43b77490c236e7348300ebb82347e61c 562 Gene3D G3DSA:3.30.413.10 130 323 6.4E-79 T 14-10-2018 TSH58p_03780 43b77490c236e7348300ebb82347e61c 562 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 63 122 2.1E-19 T 14-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TSH58p_03780 43b77490c236e7348300ebb82347e61c 562 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 345 409 3.0E-13 T 14-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TSH58p_23445 98ad04b6bce3e5782da83e5429185585 401 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 115 382 8.6E-85 T 14-10-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 TSH58p_23445 98ad04b6bce3e5782da83e5429185585 401 SUPERFAMILY SSF56322 48 385 2.62E-90 T 14-10-2018 IPR005801 ADC synthase GO:0009058 TSH58p_23445 98ad04b6bce3e5782da83e5429185585 401 Gene3D G3DSA:3.60.120.10 13 386 1.1E-118 T 14-10-2018 IPR005801 ADC synthase GO:0009058 TSH58p_23445 98ad04b6bce3e5782da83e5429185585 401 Pfam PF00425 chorismate binding enzyme 122 375 3.5E-72 T 14-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal TSH58p_15705 6882d917b5c4dcd409e8c51e1594e708 153 SUPERFAMILY SSF89095 2 151 2.2E-37 T 14-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 TSH58p_15705 6882d917b5c4dcd409e8c51e1594e708 153 Pfam PF09424 Yqey-like protein 4 150 5.5E-47 T 14-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 TSH58p_15705 6882d917b5c4dcd409e8c51e1594e708 153 Gene3D G3DSA:1.10.10.410 95 151 8.5E-18 T 14-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal TSH58p_15705 6882d917b5c4dcd409e8c51e1594e708 153 Gene3D G3DSA:1.10.1510.10 1 94 7.7E-24 T 14-10-2018 TSH58p_14865 33e5b7c1420fff4b8a7a709644079b11 139 Gene3D G3DSA:2.60.120.10 11 136 2.0E-40 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_14865 33e5b7c1420fff4b8a7a709644079b11 139 SUPERFAMILY SSF51182 22 130 1.89E-17 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_14865 33e5b7c1420fff4b8a7a709644079b11 139 Pfam PF07883 Cupin domain 55 120 4.3E-8 T 14-10-2018 IPR013096 Cupin 2, conserved barrel TSH58p_25125 408807cd5cd8e121c81ab6674d4d2166 387 Gene3D G3DSA:1.10.540.10 4 117 2.2E-30 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TSH58p_25125 408807cd5cd8e121c81ab6674d4d2166 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 370 1.0E-33 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TSH58p_25125 408807cd5cd8e121c81ab6674d4d2166 387 Gene3D G3DSA:1.20.140.10 237 381 3.8E-37 T 14-10-2018 TSH58p_25125 408807cd5cd8e121c81ab6674d4d2166 387 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 339 358 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TSH58p_25125 408807cd5cd8e121c81ab6674d4d2166 387 SUPERFAMILY SSF56645 8 244 1.14E-62 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TSH58p_25125 408807cd5cd8e121c81ab6674d4d2166 387 Gene3D G3DSA:2.40.110.10 121 236 4.9E-35 T 14-10-2018 TSH58p_25125 408807cd5cd8e121c81ab6674d4d2166 387 PIRSF PIRSF016578 234 386 2.8E-5 T 14-10-2018 TSH58p_25125 408807cd5cd8e121c81ab6674d4d2166 387 PIRSF PIRSF016578 9 196 3.1E-9 T 14-10-2018 TSH58p_25125 408807cd5cd8e121c81ab6674d4d2166 387 SUPERFAMILY SSF47203 230 384 9.34E-44 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TSH58p_25125 408807cd5cd8e121c81ab6674d4d2166 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 116 2.0E-26 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TSH58p_25125 408807cd5cd8e121c81ab6674d4d2166 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 219 5.3E-22 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TSH58p_03810 f8ca86fa1babd165eadcada66ad51cd2 624 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 431 609 1.9E-69 T 14-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 TSH58p_03810 f8ca86fa1babd165eadcada66ad51cd2 624 Gene3D G3DSA:2.40.30.10 222 308 5.2E-20 T 14-10-2018 TSH58p_03810 f8ca86fa1babd165eadcada66ad51cd2 624 SUPERFAMILY SSF52540 9 234 5.05E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_03810 f8ca86fa1babd165eadcada66ad51cd2 624 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 63 78 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site TSH58p_03810 f8ca86fa1babd165eadcada66ad51cd2 624 Pfam PF00009 Elongation factor Tu GTP binding domain 12 206 5.3E-44 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_03810 f8ca86fa1babd165eadcada66ad51cd2 624 Gene3D G3DSA:2.40.30.10 311 414 1.0E-22 T 14-10-2018 TSH58p_03810 f8ca86fa1babd165eadcada66ad51cd2 624 Gene3D G3DSA:3.40.50.300 421 614 1.0E-71 T 14-10-2018 TSH58p_03810 f8ca86fa1babd165eadcada66ad51cd2 624 Pfam PF01583 Adenylylsulphate kinase 445 595 1.1E-63 T 14-10-2018 TSH58p_03810 f8ca86fa1babd165eadcada66ad51cd2 624 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 443 614 35.84 T 14-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 TSH58p_03810 f8ca86fa1babd165eadcada66ad51cd2 624 SUPERFAMILY SSF52540 442 611 1.59E-33 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_03810 f8ca86fa1babd165eadcada66ad51cd2 624 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.9E-18 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_03810 f8ca86fa1babd165eadcada66ad51cd2 624 PRINTS PR00315 GTP-binding elongation factor signature 90 100 1.9E-18 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_03810 f8ca86fa1babd165eadcada66ad51cd2 624 PRINTS PR00315 GTP-binding elongation factor signature 106 117 1.9E-18 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_03810 f8ca86fa1babd165eadcada66ad51cd2 624 PRINTS PR00315 GTP-binding elongation factor signature 70 78 1.9E-18 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_03810 f8ca86fa1babd165eadcada66ad51cd2 624 PRINTS PR00315 GTP-binding elongation factor signature 143 152 1.9E-18 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_03810 f8ca86fa1babd165eadcada66ad51cd2 624 SUPERFAMILY SSF50465 313 412 2.83E-18 T 14-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal TSH58p_03810 f8ca86fa1babd165eadcada66ad51cd2 624 SUPERFAMILY SSF50447 219 307 6.03E-16 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSH58p_03810 f8ca86fa1babd165eadcada66ad51cd2 624 Gene3D G3DSA:3.40.50.300 2 217 1.0E-68 T 14-10-2018 TSH58p_03810 f8ca86fa1babd165eadcada66ad51cd2 624 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 11 403 3.8E-107 T 14-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 TSH58p_28260 b8cf727ac9552153d8374210f6772070 500 Gene3D G3DSA:3.40.630.10 173 495 9.5E-130 T 14-10-2018 TSH58p_28260 b8cf727ac9552153d8374210f6772070 500 SUPERFAMILY SSF53187 177 495 2.72E-120 T 14-10-2018 TSH58p_28260 b8cf727ac9552153d8374210f6772070 500 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 182 489 2.0E-123 T 14-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 TSH58p_28260 b8cf727ac9552153d8374210f6772070 500 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 18 144 2.5E-26 T 14-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 TSH58p_28260 b8cf727ac9552153d8374210f6772070 500 Gene3D G3DSA:3.40.220.10 1 172 3.5E-36 T 14-10-2018 TSH58p_28260 b8cf727ac9552153d8374210f6772070 500 SUPERFAMILY SSF52949 5 179 6.47E-31 T 14-10-2018 TSH58p_28260 b8cf727ac9552153d8374210f6772070 500 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 1 498 36.45 T 14-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 TSH58p_28260 b8cf727ac9552153d8374210f6772070 500 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 344 351 - T 14-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 TSH58p_28260 b8cf727ac9552153d8374210f6772070 500 PRINTS PR00481 Cytosol aminopeptidase signature 259 276 6.8E-55 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TSH58p_28260 b8cf727ac9552153d8374210f6772070 500 PRINTS PR00481 Cytosol aminopeptidase signature 281 302 6.8E-55 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TSH58p_28260 b8cf727ac9552153d8374210f6772070 500 PRINTS PR00481 Cytosol aminopeptidase signature 318 339 6.8E-55 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TSH58p_28260 b8cf727ac9552153d8374210f6772070 500 PRINTS PR00481 Cytosol aminopeptidase signature 369 384 6.8E-55 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TSH58p_28260 b8cf727ac9552153d8374210f6772070 500 PRINTS PR00481 Cytosol aminopeptidase signature 340 360 6.8E-55 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TSH58p_17145 fc0f76ec8ae1c5c1529aef0193be20ae 158 Pfam PF02566 OsmC-like protein 52 151 2.3E-16 T 14-10-2018 IPR003718 OsmC/Ohr family TSH58p_17145 fc0f76ec8ae1c5c1529aef0193be20ae 158 Gene3D G3DSA:3.30.300.20 2 152 3.0E-54 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta TSH58p_17145 fc0f76ec8ae1c5c1529aef0193be20ae 158 SUPERFAMILY SSF82784 5 151 4.97E-47 T 14-10-2018 IPR036102 OsmC/Ohr superfamily TSH58p_09345 419ede88680a5256219048df9137c5e0 339 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 230 244 - T 14-10-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TSH58p_09345 419ede88680a5256219048df9137c5e0 339 Gene3D G3DSA:3.40.50.720 5 331 6.0E-132 T 14-10-2018 TSH58p_09345 419ede88680a5256219048df9137c5e0 339 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 5 335 9.0E-123 T 14-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TSH58p_09345 419ede88680a5256219048df9137c5e0 339 PIRSF PIRSF000148 2 337 7.1E-118 T 14-10-2018 TSH58p_09345 419ede88680a5256219048df9137c5e0 339 SMART SM00859 4 120 8.8E-37 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TSH58p_09345 419ede88680a5256219048df9137c5e0 339 Gene3D G3DSA:3.30.360.10 129 316 6.0E-132 T 14-10-2018 TSH58p_09345 419ede88680a5256219048df9137c5e0 339 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 140 319 9.1E-52 T 14-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TSH58p_09345 419ede88680a5256219048df9137c5e0 339 SUPERFAMILY SSF51735 3 158 1.96E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_09345 419ede88680a5256219048df9137c5e0 339 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 118 2.7E-30 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TSH58p_09345 419ede88680a5256219048df9137c5e0 339 SUPERFAMILY SSF55347 133 320 5.06E-68 T 14-10-2018 TSH58p_09345 419ede88680a5256219048df9137c5e0 339 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 2 333 32.418 T 14-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TSH58p_11350 228a1b6493bc629858f3649aa40844c9 176 Pfam PF02130 Uncharacterized protein family UPF0054 21 150 4.9E-39 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 TSH58p_11350 228a1b6493bc629858f3649aa40844c9 176 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 155 24.215 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 TSH58p_11350 228a1b6493bc629858f3649aa40844c9 176 Gene3D G3DSA:3.40.390.30 1 161 3.0E-49 T 14-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 TSH58p_11350 228a1b6493bc629858f3649aa40844c9 176 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 121 131 - T 14-10-2018 IPR020549 Endoribonuclease YbeY, conserved site TSH58p_11350 228a1b6493bc629858f3649aa40844c9 176 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 42 151 3.6E-38 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 TSH58p_11350 228a1b6493bc629858f3649aa40844c9 176 SUPERFAMILY SSF55486 26 157 3.11E-45 T 14-10-2018 TSH58p_24100 571bb7b5142d2ac74955b91fa8835e1c 237 SUPERFAMILY SSF51735 1 235 2.65E-58 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_24100 571bb7b5142d2ac74955b91fa8835e1c 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 3.0E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_24100 571bb7b5142d2ac74955b91fa8835e1c 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 3.0E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_24100 571bb7b5142d2ac74955b91fa8835e1c 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 3.0E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_24100 571bb7b5142d2ac74955b91fa8835e1c 237 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 235 6.4E-46 T 14-10-2018 TSH58p_24100 571bb7b5142d2ac74955b91fa8835e1c 237 Gene3D G3DSA:3.40.50.720 1 236 3.1E-66 T 14-10-2018 TSH58p_24100 571bb7b5142d2ac74955b91fa8835e1c 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 2.5E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_24100 571bb7b5142d2ac74955b91fa8835e1c 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 2.5E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_24100 571bb7b5142d2ac74955b91fa8835e1c 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.5E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_24100 571bb7b5142d2ac74955b91fa8835e1c 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 2.5E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_24100 571bb7b5142d2ac74955b91fa8835e1c 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 2.5E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_24100 571bb7b5142d2ac74955b91fa8835e1c 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 2.5E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_10310 68430c21462be3083f9341f6865e6982 547 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 14-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TSH58p_10310 68430c21462be3083f9341f6865e6982 547 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 528 1.6E-262 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TSH58p_10310 68430c21462be3083f9341f6865e6982 547 SUPERFAMILY SSF48592 7 522 1.08E-78 T 14-10-2018 IPR027413 GroEL-like equatorial domain superfamily TSH58p_10310 68430c21462be3083f9341f6865e6982 547 Hamap MF_00600 60 kDa chaperonin [groL]. 2 545 42.728 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TSH58p_10310 68430c21462be3083f9341f6865e6982 547 SUPERFAMILY SSF54849 138 203 4.58E-24 T 14-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TSH58p_10310 68430c21462be3083f9341f6865e6982 547 PRINTS PR00298 60kDa chaperonin signature 83 110 5.2E-74 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TSH58p_10310 68430c21462be3083f9341f6865e6982 547 PRINTS PR00298 60kDa chaperonin signature 268 291 5.2E-74 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TSH58p_10310 68430c21462be3083f9341f6865e6982 547 PRINTS PR00298 60kDa chaperonin signature 398 419 5.2E-74 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TSH58p_10310 68430c21462be3083f9341f6865e6982 547 PRINTS PR00298 60kDa chaperonin signature 27 53 5.2E-74 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TSH58p_10310 68430c21462be3083f9341f6865e6982 547 PRINTS PR00298 60kDa chaperonin signature 350 375 5.2E-74 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TSH58p_10310 68430c21462be3083f9341f6865e6982 547 Gene3D G3DSA:3.30.260.10 138 410 2.4E-240 T 14-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TSH58p_10310 68430c21462be3083f9341f6865e6982 547 Gene3D G3DSA:1.10.560.10 8 522 2.4E-240 T 14-10-2018 IPR027413 GroEL-like equatorial domain superfamily TSH58p_10310 68430c21462be3083f9341f6865e6982 547 Gene3D G3DSA:3.50.7.10 173 379 2.4E-240 T 14-10-2018 IPR027409 GroEL-like apical domain superfamily TSH58p_10310 68430c21462be3083f9341f6865e6982 547 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 525 5.5E-101 T 14-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 TSH58p_10310 68430c21462be3083f9341f6865e6982 547 SUPERFAMILY SSF52029 184 376 3.14E-86 T 14-10-2018 IPR027409 GroEL-like apical domain superfamily TSH58p_19980 0623a0328d502bbdfe55c4d1b19e382a 231 SUPERFAMILY SSF56784 9 225 1.47E-53 T 14-10-2018 IPR036412 HAD-like superfamily TSH58p_19980 0623a0328d502bbdfe55c4d1b19e382a 231 Hamap MF_00495 Phosphoglycolate phosphatase [gph]. 10 226 34.645 T 14-10-2018 IPR037512 Phosphoglycolate phosphatase, prokaryotic GO:0005975|GO:0008967 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 TSH58p_19980 0623a0328d502bbdfe55c4d1b19e382a 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 10 21 4.1E-9 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_19980 0623a0328d502bbdfe55c4d1b19e382a 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 158 178 4.1E-9 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_19980 0623a0328d502bbdfe55c4d1b19e382a 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 185 198 4.1E-9 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_19980 0623a0328d502bbdfe55c4d1b19e382a 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 109 122 4.1E-9 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_19980 0623a0328d502bbdfe55c4d1b19e382a 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 140 156 4.1E-9 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_19980 0623a0328d502bbdfe55c4d1b19e382a 231 Gene3D G3DSA:3.40.50.1000 13 217 5.1E-56 T 14-10-2018 IPR023214 HAD superfamily TSH58p_19980 0623a0328d502bbdfe55c4d1b19e382a 231 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 13 224 1.7E-67 T 14-10-2018 IPR006346 2-phosphoglycolate phosphatase-like, prokaryotic GO:0016791 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 TSH58p_19980 0623a0328d502bbdfe55c4d1b19e382a 231 Gene3D G3DSA:1.10.150.240 25 95 5.1E-56 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 TSH58p_19980 0623a0328d502bbdfe55c4d1b19e382a 231 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 98 190 3.3E-10 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_19980 0623a0328d502bbdfe55c4d1b19e382a 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 14 195 1.7E-35 T 14-10-2018 TSH58p_19980 0623a0328d502bbdfe55c4d1b19e382a 231 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 90 196 1.0E-11 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_25885 27a7e7b1a9f63592d7710420525b427e 198 SUPERFAMILY SSF69754 1 99 1.96E-25 T 14-10-2018 IPR036567 Ribosome hibernation promotion factor-like TSH58p_25885 27a7e7b1a9f63592d7710420525b427e 198 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 134 188 2.0E-15 T 14-10-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal TSH58p_25885 27a7e7b1a9f63592d7710420525b427e 198 Gene3D G3DSA:3.30.505.50 148 192 5.7E-11 T 14-10-2018 IPR038416 Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain superfamily TSH58p_25885 27a7e7b1a9f63592d7710420525b427e 198 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 4 95 8.8E-18 T 14-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 TSH58p_25885 27a7e7b1a9f63592d7710420525b427e 198 Gene3D G3DSA:3.30.160.100 1 108 2.1E-20 T 14-10-2018 IPR036567 Ribosome hibernation promotion factor-like TSH58p_25885 27a7e7b1a9f63592d7710420525b427e 198 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 193 20.191 T 14-10-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid TSH58p_25885 27a7e7b1a9f63592d7710420525b427e 198 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 99 9.1E-20 T 14-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 TSH58p_16970 a1f6c1ceeb2cba0aa0eecaa5508fdfbb 298 Gene3D G3DSA:1.20.1260.10 1 199 3.4E-71 T 14-10-2018 IPR012347 Ferritin-like TSH58p_16970 a1f6c1ceeb2cba0aa0eecaa5508fdfbb 298 Pfam PF05067 Manganese containing catalase 1 266 7.5E-86 T 14-10-2018 IPR007760 Manganese catalase TSH58p_16970 a1f6c1ceeb2cba0aa0eecaa5508fdfbb 298 SUPERFAMILY SSF47240 1 285 5.56E-84 T 14-10-2018 IPR009078 Ferritin-like superfamily TSH58p_05550 747f2083749e68455ba9a7cce6865df1 258 SUPERFAMILY SSF48613 2 252 2.4E-63 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 TSH58p_05550 747f2083749e68455ba9a7cce6865df1 258 Gene3D G3DSA:1.20.910.10 1 238 8.8E-57 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 TSH58p_05550 747f2083749e68455ba9a7cce6865df1 258 TIGRFAM TIGR02111 PQQ_syn_pqqC: coenzyme PQQ biosynthesis protein C 5 249 3.4E-108 T 14-10-2018 IPR011845 Coenzyme PQQ biosynthesis protein C GO:0018189|GO:0055114 MetaCyc: PWY-6420 TSH58p_05550 747f2083749e68455ba9a7cce6865df1 258 Hamap MF_00654 Pyrroloquinoline-quinone synthase [pqqC]. 1 258 116.514 T 14-10-2018 IPR011845 Coenzyme PQQ biosynthesis protein C GO:0018189|GO:0055114 MetaCyc: PWY-6420 TSH58p_05550 747f2083749e68455ba9a7cce6865df1 258 Pfam PF03070 TENA/THI-4/PQQC family 12 229 1.0E-49 T 14-10-2018 IPR004305 Thiaminase-2/PQQC TSH58p_27450 a026b2ef0280f6c4767832715d2edfd1 246 SUPERFAMILY SSF55729 89 242 7.62E-22 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_27450 a026b2ef0280f6c4767832715d2edfd1 246 Hamap MF_00689 Aspartate/glutamate leucyltransferase [bpt]. 10 238 37.695 T 14-10-2018 IPR017138 Aspartate/glutamate leucyltransferase GO:0008914|GO:0071596 MetaCyc: PWY-7802 TSH58p_27450 a026b2ef0280f6c4767832715d2edfd1 246 Pfam PF04377 Arginine-tRNA-protein transferase, C terminus 110 232 2.2E-31 T 14-10-2018 IPR007472 N-end rule aminoacyl transferase, C-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7802 TSH58p_27450 a026b2ef0280f6c4767832715d2edfd1 246 PIRSF PIRSF037208 4 245 1.0E-79 T 14-10-2018 IPR017138 Aspartate/glutamate leucyltransferase GO:0008914|GO:0071596 MetaCyc: PWY-7802 TSH58p_27450 a026b2ef0280f6c4767832715d2edfd1 246 Pfam PF04376 Arginine-tRNA-protein transferase, N terminus 21 90 5.0E-16 T 14-10-2018 IPR007471 N-end aminoacyl transferase, N-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7802 TSH58p_27450 a026b2ef0280f6c4767832715d2edfd1 246 Gene3D G3DSA:3.40.630.30 99 239 1.3E-6 T 14-10-2018 TSH58p_24535 166d4ed66ce0993efd13ccc8dd468878 301 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 45 232 3.5E-38 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 TSH58p_24535 166d4ed66ce0993efd13ccc8dd468878 301 SUPERFAMILY SSF111369 43 215 3.4E-25 T 14-10-2018 TSH58p_24535 166d4ed66ce0993efd13ccc8dd468878 301 Pfam PF13533 Biotin-lipoyl like 46 93 8.1E-17 T 14-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain TSH58p_24535 166d4ed66ce0993efd13ccc8dd468878 301 Gene3D G3DSA:2.40.50.100 45 113 1.4E-10 T 14-10-2018 TSH58p_24535 166d4ed66ce0993efd13ccc8dd468878 301 Gene3D G3DSA:2.40.30.170 169 293 1.9E-27 T 14-10-2018 TSH58p_24535 166d4ed66ce0993efd13ccc8dd468878 301 Pfam PF13437 HlyD family secretion protein 156 236 1.5E-11 T 14-10-2018 TSH58p_23290 3aa94d090d6bdf7cf8d558b93928902f 369 Pfam PF06812 ImpA, N-terminal, type VI secretion system 18 139 6.8E-37 T 14-10-2018 IPR010657 ImpA, N-terminal TSH58p_23290 3aa94d090d6bdf7cf8d558b93928902f 369 TIGRFAM TIGR03363 VI_chp_8: type VI secretion-associated protein, ImpA family 12 361 9.8E-92 T 14-10-2018 IPR017740 Type VI secretion system-associated, ImpA TSH58p_29795 edce7ea465284bc2ad1c06c03ee15aba 183 Gene3D G3DSA:2.40.100.10 15 181 1.8E-52 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily TSH58p_29795 edce7ea465284bc2ad1c06c03ee15aba 183 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 125 137 4.0E-12 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 TSH58p_29795 edce7ea465284bc2ad1c06c03ee15aba 183 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 71 83 4.0E-12 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 TSH58p_29795 edce7ea465284bc2ad1c06c03ee15aba 183 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 138 153 4.0E-12 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 TSH58p_29795 edce7ea465284bc2ad1c06c03ee15aba 183 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 45 60 4.0E-12 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 TSH58p_29795 edce7ea465284bc2ad1c06c03ee15aba 183 PIRSF PIRSF001467 15 183 2.0E-37 T 14-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 TSH58p_29795 edce7ea465284bc2ad1c06c03ee15aba 183 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 66 83 - T 14-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 TSH58p_29795 edce7ea465284bc2ad1c06c03ee15aba 183 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 33 178 1.0E-49 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 TSH58p_29795 edce7ea465284bc2ad1c06c03ee15aba 183 SUPERFAMILY SSF50891 24 177 8.18E-54 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily TSH58p_30520 f38ae783c2b4485a41d2db778fdfb99a 327 SMART SM00861 4 178 1.8E-53 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSH58p_30520 f38ae783c2b4485a41d2db778fdfb99a 327 SUPERFAMILY SSF52518 1 203 1.28E-60 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_30520 f38ae783c2b4485a41d2db778fdfb99a 327 Pfam PF02780 Transketolase, C-terminal domain 193 314 8.3E-34 T 14-10-2018 IPR033248 Transketolase, C-terminal domain TSH58p_30520 f38ae783c2b4485a41d2db778fdfb99a 327 Gene3D G3DSA:3.40.50.920 192 323 1.8E-40 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSH58p_30520 f38ae783c2b4485a41d2db778fdfb99a 327 SUPERFAMILY SSF52922 187 323 1.31E-33 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSH58p_30520 f38ae783c2b4485a41d2db778fdfb99a 327 Pfam PF02779 Transketolase, pyrimidine binding domain 4 177 1.0E-45 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSH58p_30520 f38ae783c2b4485a41d2db778fdfb99a 327 Gene3D G3DSA:3.40.50.970 1 191 1.7E-73 T 14-10-2018 TSH58p_20930 e04a9c8658cac908e0aa64278ab5e3d5 385 PIRSF PIRSF016578 1 384 5.3E-20 T 14-10-2018 TSH58p_20930 e04a9c8658cac908e0aa64278ab5e3d5 385 Gene3D G3DSA:1.20.140.10 237 383 9.4E-53 T 14-10-2018 TSH58p_20930 e04a9c8658cac908e0aa64278ab5e3d5 385 Gene3D G3DSA:1.10.540.10 2 119 6.2E-30 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TSH58p_20930 e04a9c8658cac908e0aa64278ab5e3d5 385 SUPERFAMILY SSF47203 230 381 9.02E-56 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TSH58p_20930 e04a9c8658cac908e0aa64278ab5e3d5 385 Gene3D G3DSA:2.40.110.10 121 236 2.0E-38 T 14-10-2018 TSH58p_20930 e04a9c8658cac908e0aa64278ab5e3d5 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 379 1.4E-49 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TSH58p_20930 e04a9c8658cac908e0aa64278ab5e3d5 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 118 3.5E-27 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TSH58p_20930 e04a9c8658cac908e0aa64278ab5e3d5 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 3.8E-24 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TSH58p_20930 e04a9c8658cac908e0aa64278ab5e3d5 385 SUPERFAMILY SSF56645 3 242 6.94E-70 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TSH58p_28660 3b3f22336e63ad0f9437b4752766295f 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 1 19 - T 14-10-2018 TSH58p_28660 3b3f22336e63ad0f9437b4752766295f 341 Pfam PF13377 Periplasmic binding protein-like domain 177 341 1.2E-28 T 14-10-2018 TSH58p_28660 3b3f22336e63ad0f9437b4752766295f 341 SUPERFAMILY SSF47413 1 56 4.88E-14 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_28660 3b3f22336e63ad0f9437b4752766295f 341 SUPERFAMILY SSF53822 55 320 6.85E-53 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_28660 3b3f22336e63ad0f9437b4752766295f 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 45 1.5E-14 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TSH58p_28660 3b3f22336e63ad0f9437b4752766295f 341 Gene3D G3DSA:3.40.50.2300 61 316 9.1E-65 T 14-10-2018 TSH58p_28660 3b3f22336e63ad0f9437b4752766295f 341 SMART SM00354 1 68 2.5E-21 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TSH58p_28660 3b3f22336e63ad0f9437b4752766295f 341 Gene3D G3DSA:1.10.260.40 1 55 3.9E-18 T 14-10-2018 TSH58p_28660 3b3f22336e63ad0f9437b4752766295f 341 Gene3D G3DSA:3.40.50.2300 166 298 9.1E-65 T 14-10-2018 TSH58p_11010 b977573dba73359707cf9eac69e625ce 204 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 24 179 2.7E-37 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 TSH58p_11010 b977573dba73359707cf9eac69e625ce 204 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 12 204 24.554 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 TSH58p_11010 b977573dba73359707cf9eac69e625ce 204 Gene3D G3DSA:3.40.50.150 2 197 7.0E-54 T 14-10-2018 TSH58p_11010 b977573dba73359707cf9eac69e625ce 204 Pfam PF02527 rRNA small subunit methyltransferase G 22 181 5.6E-39 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 TSH58p_11010 b977573dba73359707cf9eac69e625ce 204 SUPERFAMILY SSF53335 7 181 8.61E-32 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_11010 b977573dba73359707cf9eac69e625ce 204 PIRSF PIRSF003078 1 194 2.4E-43 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 TSH58p_05775 3aa5ca0ccf20f50f2330536b84f525e7 1160 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 305 739 6.1E-168 T 14-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSH58p_05775 3aa5ca0ccf20f50f2330536b84f525e7 1160 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 1040 0.0 T 14-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSH58p_05775 3aa5ca0ccf20f50f2330536b84f525e7 1160 SUPERFAMILY SSF160975 842 892 8.11E-6 T 14-10-2018 TSH58p_05775 3aa5ca0ccf20f50f2330536b84f525e7 1160 Gene3D G3DSA:3.20.20.140 1 282 2.3E-81 T 14-10-2018 TSH58p_05775 3aa5ca0ccf20f50f2330536b84f525e7 1160 Gene3D G3DSA:1.10.10.1600 451 530 1.2E-25 T 14-10-2018 TSH58p_05775 3aa5ca0ccf20f50f2330536b84f525e7 1160 Pfam PF02811 PHP domain 8 184 1.9E-36 T 14-10-2018 IPR004013 PHP domain GO:0003824 TSH58p_05775 3aa5ca0ccf20f50f2330536b84f525e7 1160 SUPERFAMILY SSF89550 6 276 1.73E-12 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TSH58p_05775 3aa5ca0ccf20f50f2330536b84f525e7 1160 Pfam PF14579 Helix-hairpin-helix motif 814 906 1.1E-25 T 14-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSH58p_05775 3aa5ca0ccf20f50f2330536b84f525e7 1160 SMART SM00481 7 74 1.2E-18 T 14-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal TSH58p_11710 b9055b41b061d7aad92f12fcef3e7832 145 SUPERFAMILY SSF75169 7 134 6.08E-12 T 14-10-2018 IPR027396 DsrEFH-like TSH58p_11710 b9055b41b061d7aad92f12fcef3e7832 145 Pfam PF02635 DsrE/DsrF-like family 18 130 1.9E-6 T 14-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein TSH58p_11710 b9055b41b061d7aad92f12fcef3e7832 145 Gene3D G3DSA:3.40.1260.10 2 145 2.8E-18 T 14-10-2018 IPR027396 DsrEFH-like TSH58p_07535 930241809e293b24dfe3544854c3ca0a 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 9.7E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_07535 930241809e293b24dfe3544854c3ca0a 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 9.7E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_07535 930241809e293b24dfe3544854c3ca0a 216 Gene3D G3DSA:1.10.357.10 10 209 2.9E-47 T 14-10-2018 TSH58p_07535 930241809e293b24dfe3544854c3ca0a 216 SUPERFAMILY SSF46689 9 88 3.49E-22 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_07535 930241809e293b24dfe3544854c3ca0a 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 4.5E-20 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_07535 930241809e293b24dfe3544854c3ca0a 216 Pfam PF16859 Bacterial transcriptional repressor C-terminal 95 180 1.0E-10 T 14-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal TSH58p_07535 930241809e293b24dfe3544854c3ca0a 216 SUPERFAMILY SSF48498 89 208 7.67E-21 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 SMART SM00448 9 121 8.7E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 SMART SM00448 824 936 3.6E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 SUPERFAMILY SSF52172 825 942 2.13E-28 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 SMART SM00387 675 799 1.6E-26 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 Pfam PF08448 PAS fold 153 260 3.9E-14 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 Pfam PF08448 PAS fold 436 544 1.1E-6 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 Gene3D G3DSA:3.30.450.20 143 267 5.6E-25 T 14-10-2018 TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 Gene3D G3DSA:3.30.450.20 427 560 1.0E-15 T 14-10-2018 TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 SUPERFAMILY SSF55874 625 797 1.83E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 SMART SM00086 502 544 0.078 T 14-10-2018 IPR001610 PAC motif TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 SMART SM00086 216 258 0.68 T 14-10-2018 IPR001610 PAC motif TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 SMART SM00086 342 384 4.2E-9 T 14-10-2018 IPR001610 PAC motif TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 138 262 3.5E-17 T 14-10-2018 IPR000014 PAS domain TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 428 550 6.0E-14 T 14-10-2018 IPR000014 PAS domain TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 266 389 1.5E-14 T 14-10-2018 IPR000014 PAS domain TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 Gene3D G3DSA:3.30.450.20 268 380 1.3E-32 T 14-10-2018 TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 Gene3D G3DSA:1.10.287.130 561 632 3.4E-20 T 14-10-2018 TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 Gene3D G3DSA:3.40.50.2300 816 946 1.0E-25 T 14-10-2018 TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 Gene3D G3DSA:3.40.50.2300 6 142 1.1E-20 T 14-10-2018 TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 SUPERFAMILY SSF47384 557 631 1.2E-10 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 Pfam PF00512 His Kinase A (phospho-acceptor) domain 566 632 5.8E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 SUPERFAMILY SSF55785 422 542 3.07E-16 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 Pfam PF08447 PAS fold 294 377 2.2E-19 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 SMART SM00388 566 634 4.6E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 676 796 4.8E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 SUPERFAMILY SSF55785 155 266 1.54E-20 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 Pfam PF00072 Response regulator receiver domain 826 936 1.0E-18 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 Pfam PF00072 Response regulator receiver domain 11 121 1.9E-13 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 SUPERFAMILY SSF52172 10 146 1.57E-23 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 SMART SM00091 428 495 7.4E-6 T 14-10-2018 IPR000014 PAS domain TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 SMART SM00091 270 336 1.4E-4 T 14-10-2018 IPR000014 PAS domain TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 SMART SM00091 142 210 2.4E-7 T 14-10-2018 IPR000014 PAS domain TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 PRINTS PR00344 Bacterial sensor protein C-terminal signature 759 777 1.2E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 PRINTS PR00344 Bacterial sensor protein C-terminal signature 746 756 1.2E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 PRINTS PR00344 Bacterial sensor protein C-terminal signature 783 796 1.2E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 PRINTS PR00344 Bacterial sensor protein C-terminal signature 728 742 1.2E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 SUPERFAMILY SSF55785 255 381 5.64E-28 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_21030 ef53a7bb8d3839f718a160fb1b4d8dc3 963 Gene3D G3DSA:3.30.565.10 638 802 2.8E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_09775 76afdd22b3e1064d4671681935d42e7a 72 Pfam PF06568 Domain of unknown function (DUF1127) 27 58 5.2E-12 T 14-10-2018 IPR009506 Protein of unknown function DUF1127 TSH58p_26425 b7ab7f98c1b58268b9e4e60f202f1d2e 523 Gene3D G3DSA:1.10.287.130 130 218 6.9E-12 T 14-10-2018 TSH58p_26425 b7ab7f98c1b58268b9e4e60f202f1d2e 523 SMART SM00388 155 220 1.2E-7 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_26425 b7ab7f98c1b58268b9e4e60f202f1d2e 523 SMART SM00387 264 375 2.6E-27 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_26425 b7ab7f98c1b58268b9e4e60f202f1d2e 523 PRINTS PR00344 Bacterial sensor protein C-terminal signature 300 314 3.4E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_26425 b7ab7f98c1b58268b9e4e60f202f1d2e 523 PRINTS PR00344 Bacterial sensor protein C-terminal signature 335 353 3.4E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_26425 b7ab7f98c1b58268b9e4e60f202f1d2e 523 PRINTS PR00344 Bacterial sensor protein C-terminal signature 318 328 3.4E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_26425 b7ab7f98c1b58268b9e4e60f202f1d2e 523 PRINTS PR00344 Bacterial sensor protein C-terminal signature 359 372 3.4E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_26425 b7ab7f98c1b58268b9e4e60f202f1d2e 523 SUPERFAMILY SSF55874 209 371 2.1E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_26425 b7ab7f98c1b58268b9e4e60f202f1d2e 523 Pfam PF00512 His Kinase A (phospho-acceptor) domain 155 220 6.1E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_26425 b7ab7f98c1b58268b9e4e60f202f1d2e 523 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 265 372 1.1E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_26425 b7ab7f98c1b58268b9e4e60f202f1d2e 523 Gene3D G3DSA:3.30.565.10 219 375 3.7E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_26425 b7ab7f98c1b58268b9e4e60f202f1d2e 523 Gene3D G3DSA:3.40.50.2300 397 522 5.7E-22 T 14-10-2018 TSH58p_26425 b7ab7f98c1b58268b9e4e60f202f1d2e 523 SMART SM00448 400 514 1.8E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_26425 b7ab7f98c1b58268b9e4e60f202f1d2e 523 Pfam PF00072 Response regulator receiver domain 402 514 1.1E-14 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_26425 b7ab7f98c1b58268b9e4e60f202f1d2e 523 SUPERFAMILY SSF52172 398 517 1.41E-24 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_26425 b7ab7f98c1b58268b9e4e60f202f1d2e 523 SUPERFAMILY SSF47384 139 220 3.73E-13 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_18340 6b0fda77f3b1b3e7c3a4e27a9d2e13a6 517 Pfam PF13847 Methyltransferase domain 46 162 4.0E-14 T 14-10-2018 IPR025714 Methyltransferase domain TSH58p_18340 6b0fda77f3b1b3e7c3a4e27a9d2e13a6 517 Gene3D G3DSA:3.40.50.150 30 205 1.7E-21 T 14-10-2018 TSH58p_18340 6b0fda77f3b1b3e7c3a4e27a9d2e13a6 517 SUPERFAMILY SSF53335 42 179 5.31E-24 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_18340 6b0fda77f3b1b3e7c3a4e27a9d2e13a6 517 Pfam PF10119 Predicted methyltransferase regulatory domain 223 306 1.4E-28 T 14-10-2018 IPR018773 Methyltransferase regulatory domain, predicted TSH58p_19095 78149a07dee45b880f806068018e6387 736 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 497 526 1.3E-18 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_19095 78149a07dee45b880f806068018e6387 736 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 574 601 1.3E-18 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_19095 78149a07dee45b880f806068018e6387 736 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 603 632 1.3E-18 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_19095 78149a07dee45b880f806068018e6387 736 Pfam PF00672 HAMP domain 387 434 1.6E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_19095 78149a07dee45b880f806068018e6387 736 Gene3D G3DSA:1.20.1480.50 348 443 4.8E-11 T 14-10-2018 TSH58p_19095 78149a07dee45b880f806068018e6387 736 Gene3D G3DSA:1.10.287.950 444 733 9.3E-52 T 14-10-2018 TSH58p_19095 78149a07dee45b880f806068018e6387 736 SUPERFAMILY SSF58104 407 729 4.05E-60 T 14-10-2018 TSH58p_19095 78149a07dee45b880f806068018e6387 736 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 548 700 3.3E-30 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_19095 78149a07dee45b880f806068018e6387 736 SMART SM00304 387 439 4.2E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_19095 78149a07dee45b880f806068018e6387 736 SMART SM00283 476 730 3.0E-43 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_29930 8400543534243b166149e1f3bb79a3ac 481 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 227 242 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 TSH58p_29930 8400543534243b166149e1f3bb79a3ac 481 Pfam PF02954 Bacterial regulatory protein, Fis family 432 470 1.3E-11 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_29930 8400543534243b166149e1f3bb79a3ac 481 Gene3D G3DSA:3.40.50.300 132 311 2.6E-65 T 14-10-2018 TSH58p_29930 8400543534243b166149e1f3bb79a3ac 481 Gene3D G3DSA:1.10.10.60 386 474 1.4E-22 T 14-10-2018 TSH58p_29930 8400543534243b166149e1f3bb79a3ac 481 Pfam PF00158 Sigma-54 interaction domain 141 307 3.1E-69 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 TSH58p_29930 8400543534243b166149e1f3bb79a3ac 481 Gene3D G3DSA:3.40.50.2300 2 131 8.1E-33 T 14-10-2018 TSH58p_29930 8400543534243b166149e1f3bb79a3ac 481 SMART SM00382 161 304 8.1E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_29930 8400543534243b166149e1f3bb79a3ac 481 Pfam PF00072 Response regulator receiver domain 6 115 7.9E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_29930 8400543534243b166149e1f3bb79a3ac 481 SUPERFAMILY SSF52540 141 382 1.13E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_29930 8400543534243b166149e1f3bb79a3ac 481 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 353 362 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site TSH58p_29930 8400543534243b166149e1f3bb79a3ac 481 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 455 475 4.9E-11 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_29930 8400543534243b166149e1f3bb79a3ac 481 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 438 455 4.9E-11 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_29930 8400543534243b166149e1f3bb79a3ac 481 SMART SM00448 4 115 2.5E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_29930 8400543534243b166149e1f3bb79a3ac 481 SUPERFAMILY SSF46689 353 474 7.62E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_29930 8400543534243b166149e1f3bb79a3ac 481 SUPERFAMILY SSF52172 2 185 9.96E-43 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_29930 8400543534243b166149e1f3bb79a3ac 481 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 6 472 2.9E-230 T 14-10-2018 IPR010114 DNA-binding transcriptional regulator NtrC GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 TSH58p_29930 8400543534243b166149e1f3bb79a3ac 481 Gene3D G3DSA:1.10.8.60 312 385 4.7E-23 T 14-10-2018 TSH58p_00415 d6c768b741441a66c66e882e47353cca 643 SUPERFAMILY SSF56801 10 601 3.27E-101 T 14-10-2018 TSH58p_00415 d6c768b741441a66c66e882e47353cca 643 Gene3D G3DSA:3.40.50.12780 319 467 1.8E-33 T 14-10-2018 TSH58p_00415 d6c768b741441a66c66e882e47353cca 643 Pfam PF00501 AMP-binding enzyme 19 468 3.6E-79 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_00415 d6c768b741441a66c66e882e47353cca 643 Gene3D G3DSA:3.40.50.12780 3 307 1.5E-39 T 14-10-2018 TSH58p_00415 d6c768b741441a66c66e882e47353cca 643 ProSitePatterns PS00455 Putative AMP-binding domain signature. 191 202 - T 14-10-2018 IPR020845 AMP-binding, conserved site TSH58p_16285 218db230fd873e4b19f70a68d32e2f93 209 Gene3D G3DSA:1.10.8.10 158 207 3.0E-8 T 14-10-2018 TSH58p_16285 218db230fd873e4b19f70a68d32e2f93 209 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 187 2.7E-35 T 14-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 TSH58p_16285 218db230fd873e4b19f70a68d32e2f93 209 SUPERFAMILY SSF50249 1 62 2.91E-15 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_16285 218db230fd873e4b19f70a68d32e2f93 209 Gene3D G3DSA:1.10.150.20 66 137 1.6E-22 T 14-10-2018 TSH58p_16285 218db230fd873e4b19f70a68d32e2f93 209 SUPERFAMILY SSF47781 64 133 1.67E-20 T 14-10-2018 IPR010994 RuvA domain 2-like TSH58p_16285 218db230fd873e4b19f70a68d32e2f93 209 Pfam PF01330 RuvA N terminal domain 1 61 1.4E-18 T 14-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 TSH58p_16285 218db230fd873e4b19f70a68d32e2f93 209 Pfam PF07499 RuvA, C-terminal domain 161 208 1.6E-10 T 14-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 TSH58p_16285 218db230fd873e4b19f70a68d32e2f93 209 Pfam PF14520 Helix-hairpin-helix domain 71 129 1.2E-12 T 14-10-2018 TSH58p_16285 218db230fd873e4b19f70a68d32e2f93 209 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 208 27.343 T 14-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 TSH58p_16285 218db230fd873e4b19f70a68d32e2f93 209 Gene3D G3DSA:2.40.50.140 1 65 2.1E-21 T 14-10-2018 TSH58p_16285 218db230fd873e4b19f70a68d32e2f93 209 SUPERFAMILY SSF46929 161 208 1.96E-8 T 14-10-2018 IPR036267 RuvA, C-terminal domain superfamily TSH58p_16285 218db230fd873e4b19f70a68d32e2f93 209 SMART SM00278 72 91 100.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TSH58p_16285 218db230fd873e4b19f70a68d32e2f93 209 SMART SM00278 107 126 4.8 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TSH58p_20110 c9fd532a04dec283b25361359502a74f 295 TIGRFAM TIGR03818 MotA1: flagellar motor stator protein MotA 1 279 2.1E-104 T 14-10-2018 IPR022522 Flagellar motor stator, MotA TSH58p_20110 c9fd532a04dec283b25361359502a74f 295 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 205 222 - T 14-10-2018 IPR000540 Flagellar motor protein MotA, conserved site TSH58p_20110 c9fd532a04dec283b25361359502a74f 295 Pfam PF01618 MotA/TolQ/ExbB proton channel family 138 224 4.3E-10 T 14-10-2018 IPR002898 MotA/TolQ/ExbB proton channel TSH58p_32610 3f95c8b273e3925b3623e9fcd5d1bafc 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 169 1.2E-23 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TSH58p_32610 3f95c8b273e3925b3623e9fcd5d1bafc 177 Gene3D G3DSA:1.10.1740.10 1 77 5.3E-10 T 14-10-2018 TSH58p_32610 3f95c8b273e3925b3623e9fcd5d1bafc 177 Pfam PF04542 Sigma-70 region 2 16 79 5.7E-13 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_32610 3f95c8b273e3925b3623e9fcd5d1bafc 177 SUPERFAMILY SSF88659 96 172 1.14E-16 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSH58p_32610 3f95c8b273e3925b3623e9fcd5d1bafc 177 Pfam PF08281 Sigma-70, region 4 114 166 5.6E-14 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_32610 3f95c8b273e3925b3623e9fcd5d1bafc 177 Gene3D G3DSA:1.10.10.10 87 174 3.2E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_32610 3f95c8b273e3925b3623e9fcd5d1bafc 177 SUPERFAMILY SSF88946 8 77 1.1E-13 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_11120 277e0d1c37d1f5c9592077a1dcf5e4b9 122 Gene3D G3DSA:3.30.428.10 1 120 1.3E-30 T 14-10-2018 IPR036265 HIT-like superfamily TSH58p_11120 277e0d1c37d1f5c9592077a1dcf5e4b9 122 PRINTS PR00332 Histidine triad family signature 100 110 2.2E-19 T 14-10-2018 IPR001310 Histidine triad (HIT) protein TSH58p_11120 277e0d1c37d1f5c9592077a1dcf5e4b9 122 PRINTS PR00332 Histidine triad family signature 31 49 2.2E-19 T 14-10-2018 IPR001310 Histidine triad (HIT) protein TSH58p_11120 277e0d1c37d1f5c9592077a1dcf5e4b9 122 PRINTS PR00332 Histidine triad family signature 10 26 2.2E-19 T 14-10-2018 IPR001310 Histidine triad (HIT) protein TSH58p_11120 277e0d1c37d1f5c9592077a1dcf5e4b9 122 SUPERFAMILY SSF54197 4 117 1.86E-31 T 14-10-2018 IPR036265 HIT-like superfamily TSH58p_11120 277e0d1c37d1f5c9592077a1dcf5e4b9 122 Pfam PF01230 HIT domain 16 114 6.4E-28 T 14-10-2018 IPR001310 Histidine triad (HIT) protein TSH58p_11120 277e0d1c37d1f5c9592077a1dcf5e4b9 122 ProSitePatterns PS00892 HIT domain signature. 93 111 - T 14-10-2018 IPR019808 Histidine triad, conserved site TSH58p_22145 f27dbb230004eab2da9556c6fcdf2c93 936 Gene3D G3DSA:2.120.10.90 525 756 2.4E-77 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal TSH58p_22145 f27dbb230004eab2da9556c6fcdf2c93 936 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 36 493 2.8E-151 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TSH58p_22145 f27dbb230004eab2da9556c6fcdf2c93 936 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 793 840 4.3E-12 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TSH58p_22145 f27dbb230004eab2da9556c6fcdf2c93 936 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 533 580 1.1E-13 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TSH58p_22145 f27dbb230004eab2da9556c6fcdf2c93 936 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 691 736 5.0E-12 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TSH58p_22145 f27dbb230004eab2da9556c6fcdf2c93 936 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 643 688 4.4E-8 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TSH58p_22145 f27dbb230004eab2da9556c6fcdf2c93 936 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 845 890 2.7E-10 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TSH58p_22145 f27dbb230004eab2da9556c6fcdf2c93 936 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 585 632 4.5E-4 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TSH58p_22145 f27dbb230004eab2da9556c6fcdf2c93 936 SUPERFAMILY SSF101904 528 897 2.49E-98 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal TSH58p_22145 f27dbb230004eab2da9556c6fcdf2c93 936 Gene3D G3DSA:3.30.1360.40 240 336 1.8E-219 T 14-10-2018 TSH58p_22145 f27dbb230004eab2da9556c6fcdf2c93 936 SMART SM00434 15 494 1.7E-277 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TSH58p_22145 f27dbb230004eab2da9556c6fcdf2c93 936 Gene3D G3DSA:2.120.10.90 769 892 8.7E-30 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal TSH58p_22145 f27dbb230004eab2da9556c6fcdf2c93 936 Gene3D G3DSA:1.10.268.10 373 488 1.8E-219 T 14-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 TSH58p_22145 f27dbb230004eab2da9556c6fcdf2c93 936 Gene3D G3DSA:3.90.199.10 37 516 1.8E-219 T 14-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 TSH58p_22145 f27dbb230004eab2da9556c6fcdf2c93 936 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 9 892 23.783 T 14-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TSH58p_22145 f27dbb230004eab2da9556c6fcdf2c93 936 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 12 891 0.0 T 14-10-2018 TSH58p_22145 f27dbb230004eab2da9556c6fcdf2c93 936 SUPERFAMILY SSF56719 34 516 1.7E-177 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 TSH58p_01480 5a15a4c1fb7ea5c77758743f2d4a0cfd 242 Pfam PF00005 ABC transporter 21 160 1.3E-21 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_01480 5a15a4c1fb7ea5c77758743f2d4a0cfd 242 Gene3D G3DSA:3.40.50.300 2 224 2.2E-49 T 14-10-2018 TSH58p_01480 5a15a4c1fb7ea5c77758743f2d4a0cfd 242 SUPERFAMILY SSF52540 4 221 1.28E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_01480 5a15a4c1fb7ea5c77758743f2d4a0cfd 242 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_01480 5a15a4c1fb7ea5c77758743f2d4a0cfd 242 SMART SM00382 30 210 3.4E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_13665 864a0037051d6491961ef4187238b098 479 Gene3D G3DSA:1.10.1140.10 359 479 4.1E-60 T 14-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSH58p_13665 864a0037051d6491961ef4187238b098 479 PIRSF PIRSF039072 1 479 6.3E-286 T 14-10-2018 TSH58p_13665 864a0037051d6491961ef4187238b098 479 Hamap MF_01347 ATP synthase subunit beta [atpB]. 9 474 58.182 T 14-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 TSH58p_13665 864a0037051d6491961ef4187238b098 479 SUPERFAMILY SSF47917 359 474 2.54E-54 T 14-10-2018 TSH58p_13665 864a0037051d6491961ef4187238b098 479 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 347 356 - T 14-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSH58p_13665 864a0037051d6491961ef4187238b098 479 Gene3D G3DSA:2.40.10.170 7 82 2.0E-34 T 14-10-2018 TSH58p_13665 864a0037051d6491961ef4187238b098 479 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 11 474 4.4E-255 T 14-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 TSH58p_13665 864a0037051d6491961ef4187238b098 479 SUPERFAMILY SSF50615 8 82 1.67E-26 T 14-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSH58p_13665 864a0037051d6491961ef4187238b098 479 SMART SM00382 149 333 6.3E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_13665 864a0037051d6491961ef4187238b098 479 SUPERFAMILY SSF52540 84 361 8.07E-88 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_13665 864a0037051d6491961ef4187238b098 479 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 137 356 4.9E-62 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSH58p_13665 864a0037051d6491961ef4187238b098 479 Gene3D G3DSA:3.40.50.300 83 358 1.4E-117 T 14-10-2018 TSH58p_13665 864a0037051d6491961ef4187238b098 479 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 14 80 1.8E-23 T 14-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSH58p_11490 129ea296f65bd5cba4d301330d96e48b 313 SUPERFAMILY SSF51735 1 139 8.42E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_11490 129ea296f65bd5cba4d301330d96e48b 313 Gene3D G3DSA:3.40.50.720 1 141 6.2E-49 T 14-10-2018 TSH58p_11490 129ea296f65bd5cba4d301330d96e48b 313 SUPERFAMILY SSF56327 140 306 2.37E-46 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 TSH58p_11490 129ea296f65bd5cba4d301330d96e48b 313 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 1 139 1.9E-35 T 14-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 TSH58p_11490 129ea296f65bd5cba4d301330d96e48b 313 PIRSF PIRSF000102 1 312 1.4E-94 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TSH58p_11490 129ea296f65bd5cba4d301330d96e48b 313 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 169 175 - T 14-10-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 TSH58p_11490 129ea296f65bd5cba4d301330d96e48b 313 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 1 309 36.538 T 14-10-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 TSH58p_11490 129ea296f65bd5cba4d301330d96e48b 313 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 142 309 1.7E-21 T 14-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 TSH58p_11490 129ea296f65bd5cba4d301330d96e48b 313 Gene3D G3DSA:3.90.110.10 142 309 4.3E-51 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 TSH58p_11490 129ea296f65bd5cba4d301330d96e48b 313 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 5 303 2.7E-102 T 14-10-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 TSH58p_11490 129ea296f65bd5cba4d301330d96e48b 313 PRINTS PR00086 L-lactate dehydrogenase signature 113 133 1.6E-37 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TSH58p_11490 129ea296f65bd5cba4d301330d96e48b 313 PRINTS PR00086 L-lactate dehydrogenase signature 137 155 1.6E-37 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TSH58p_11490 129ea296f65bd5cba4d301330d96e48b 313 PRINTS PR00086 L-lactate dehydrogenase signature 167 180 1.6E-37 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TSH58p_11490 129ea296f65bd5cba4d301330d96e48b 313 PRINTS PR00086 L-lactate dehydrogenase signature 2 26 1.6E-37 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TSH58p_11490 129ea296f65bd5cba4d301330d96e48b 313 PRINTS PR00086 L-lactate dehydrogenase signature 27 51 1.6E-37 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TSH58p_30700 a079332c90e642d9823ac6f72a4af49a 200 Pfam PF00857 Isochorismatase family 25 194 8.0E-37 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 TSH58p_30700 a079332c90e642d9823ac6f72a4af49a 200 SUPERFAMILY SSF52499 17 194 6.02E-48 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TSH58p_30700 a079332c90e642d9823ac6f72a4af49a 200 Gene3D G3DSA:3.40.50.850 2 197 2.5E-49 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TSH58p_08945 10a716e29e23f4f43c0673d5fee07313 691 SMART SM00843 617 682 3.4E-34 T 14-10-2018 IPR018541 FtsK gamma domain TSH58p_08945 10a716e29e23f4f43c0673d5fee07313 691 SUPERFAMILY SSF46785 617 682 3.17E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_08945 10a716e29e23f4f43c0673d5fee07313 691 Gene3D G3DSA:1.10.10.10 613 678 4.7E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_08945 10a716e29e23f4f43c0673d5fee07313 691 Gene3D G3DSA:3.40.50.300 297 600 1.7E-118 T 14-10-2018 TSH58p_08945 10a716e29e23f4f43c0673d5fee07313 691 Pfam PF09397 Ftsk gamma domain 619 679 2.2E-25 T 14-10-2018 IPR018541 FtsK gamma domain TSH58p_08945 10a716e29e23f4f43c0673d5fee07313 691 SUPERFAMILY SSF52540 287 586 1.45E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_08945 10a716e29e23f4f43c0673d5fee07313 691 Pfam PF01580 FtsK/SpoIIIE family 300 515 3.4E-66 T 14-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 TSH58p_08945 10a716e29e23f4f43c0673d5fee07313 691 SMART SM00382 335 536 8.3E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_08945 10a716e29e23f4f43c0673d5fee07313 691 Gene3D G3DSA:3.30.980.40 192 296 3.8E-27 T 14-10-2018 TSH58p_10200 9e65dfe9fd9b07dbef49217f8094805b 626 Gene3D G3DSA:3.20.20.450 19 273 8.6E-56 T 14-10-2018 IPR035919 EAL domain superfamily TSH58p_10200 9e65dfe9fd9b07dbef49217f8094805b 626 Pfam PF00990 Diguanylate cyclase, GGDEF domain 432 532 2.0E-15 T 14-10-2018 IPR000160 GGDEF domain TSH58p_10200 9e65dfe9fd9b07dbef49217f8094805b 626 Pfam PF00563 EAL domain 36 263 5.7E-46 T 14-10-2018 IPR001633 EAL domain TSH58p_10200 9e65dfe9fd9b07dbef49217f8094805b 626 Gene3D G3DSA:3.30.70.270 424 589 4.8E-22 T 14-10-2018 TSH58p_10200 9e65dfe9fd9b07dbef49217f8094805b 626 SMART SM00052 21 268 1.4E-35 T 14-10-2018 IPR001633 EAL domain TSH58p_10200 9e65dfe9fd9b07dbef49217f8094805b 626 SUPERFAMILY SSF55073 434 535 4.47E-19 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_10200 9e65dfe9fd9b07dbef49217f8094805b 626 SUPERFAMILY SSF54631 313 420 7.28E-7 T 14-10-2018 TSH58p_10200 9e65dfe9fd9b07dbef49217f8094805b 626 SUPERFAMILY SSF141868 36 263 1.29E-52 T 14-10-2018 IPR035919 EAL domain superfamily TSH58p_10200 9e65dfe9fd9b07dbef49217f8094805b 626 Gene3D G3DSA:3.10.580.10 289 423 1.6E-5 T 14-10-2018 TSH58p_10200 9e65dfe9fd9b07dbef49217f8094805b 626 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 428 535 1.2E-12 T 14-10-2018 IPR000160 GGDEF domain TSH58p_10200 9e65dfe9fd9b07dbef49217f8094805b 626 SMART SM00267 418 561 1.4E-8 T 14-10-2018 IPR000160 GGDEF domain TSH58p_22950 909f8c71a0392bafbec2cebb470978c7 294 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 72 1.6E-20 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_22950 909f8c71a0392bafbec2cebb470978c7 294 Gene3D G3DSA:3.40.1410.10 85 240 2.2E-38 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TSH58p_22950 909f8c71a0392bafbec2cebb470978c7 294 Gene3D G3DSA:1.10.10.10 3 79 2.3E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_22950 909f8c71a0392bafbec2cebb470978c7 294 SUPERFAMILY SSF64288 60 238 6.14E-44 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TSH58p_22950 909f8c71a0392bafbec2cebb470978c7 294 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 1.5E-8 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_22950 909f8c71a0392bafbec2cebb470978c7 294 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 1.5E-8 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_22950 909f8c71a0392bafbec2cebb470978c7 294 SMART SM00345 13 72 6.0E-24 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_22950 909f8c71a0392bafbec2cebb470978c7 294 Pfam PF07702 UTRA domain 95 232 1.7E-31 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 TSH58p_22950 909f8c71a0392bafbec2cebb470978c7 294 SUPERFAMILY SSF46785 10 81 1.91E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_22950 909f8c71a0392bafbec2cebb470978c7 294 SMART SM00866 94 233 4.1E-33 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 TSH58p_01820 b7ee968737898f2b85a943d2cf6ba27e 220 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 110 6.7E-30 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 TSH58p_01820 b7ee968737898f2b85a943d2cf6ba27e 220 SUPERFAMILY SSF161098 13 201 2.09E-48 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_01820 b7ee968737898f2b85a943d2cf6ba27e 220 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 216 4.6E-24 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_01820 b7ee968737898f2b85a943d2cf6ba27e 220 Gene3D G3DSA:1.10.3720.10 1 217 2.4E-60 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_22970 505bbfc3960871b61638cc20fe5d7113 229 Pfam PF00005 ABC transporter 17 158 5.5E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_22970 505bbfc3960871b61638cc20fe5d7113 229 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 2 229 2.0E-100 T 14-10-2018 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE TSH58p_22970 505bbfc3960871b61638cc20fe5d7113 229 Gene3D G3DSA:3.40.50.300 1 228 2.7E-64 T 14-10-2018 TSH58p_22970 505bbfc3960871b61638cc20fe5d7113 229 SUPERFAMILY SSF52540 1 220 1.33E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_22970 505bbfc3960871b61638cc20fe5d7113 229 SMART SM00382 26 208 2.0E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_25375 3643ccb86140736d947a74194fca7252 309 Gene3D G3DSA:3.40.50.720 78 273 1.6E-70 T 14-10-2018 TSH58p_25375 3643ccb86140736d947a74194fca7252 309 SUPERFAMILY SSF52283 9 113 7.44E-11 T 14-10-2018 TSH58p_25375 3643ccb86140736d947a74194fca7252 309 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 20 306 3.4E-8 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 TSH58p_25375 3643ccb86140736d947a74194fca7252 309 Gene3D G3DSA:3.40.50.720 8 299 1.6E-70 T 14-10-2018 TSH58p_25375 3643ccb86140736d947a74194fca7252 309 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 93 275 9.9E-49 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TSH58p_25375 3643ccb86140736d947a74194fca7252 309 SUPERFAMILY SSF51735 81 276 1.56E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_25375 3643ccb86140736d947a74194fca7252 309 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 208 224 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TSH58p_21785 f3bc248714eb568e7f4f8f310529b44c 240 SMART SM00796 3 203 2.4E-80 T 14-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D TSH58p_21785 f3bc248714eb568e7f4f8f310529b44c 240 SUPERFAMILY SSF50891 89 219 1.74E-44 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily TSH58p_21785 f3bc248714eb568e7f4f8f310529b44c 240 SUPERFAMILY SSF160467 4 94 3.14E-20 T 14-10-2018 TSH58p_21785 f3bc248714eb568e7f4f8f310529b44c 240 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 9 211 7.4E-54 T 14-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 TSH58p_21785 f3bc248714eb568e7f4f8f310529b44c 240 Gene3D G3DSA:2.40.100.10 89 227 2.7E-53 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily TSH58p_21785 f3bc248714eb568e7f4f8f310529b44c 240 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 3 203 2.5E-70 T 14-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D TSH58p_21785 f3bc248714eb568e7f4f8f310529b44c 240 Gene3D G3DSA:3.30.1360.40 4 79 5.5E-21 T 14-10-2018 TSH58p_10015 a29f9bce3cb799d53d4c10024c740d70 221 Pfam PF07298 NnrU protein 6 217 2.9E-41 T 14-10-2018 IPR009915 NnrU domain TSH58p_05830 8220ca85a6a68cbdb6bb1c4f976c8246 134 Gene3D G3DSA:3.10.180.10 1 134 5.8E-41 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSH58p_05830 8220ca85a6a68cbdb6bb1c4f976c8246 134 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 118 2.4E-23 T 14-10-2018 TSH58p_05830 8220ca85a6a68cbdb6bb1c4f976c8246 134 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 4 133 1.3E-48 T 14-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 TSH58p_05830 8220ca85a6a68cbdb6bb1c4f976c8246 134 SUPERFAMILY SSF54593 1 133 1.51E-37 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSH58p_10970 1b0353e295e2b41d44f04ea6a2fee372 390 SUPERFAMILY SSF56935 21 390 2.47E-32 T 14-10-2018 TSH58p_10970 1b0353e295e2b41d44f04ea6a2fee372 390 Gene3D G3DSA:2.40.160.10 28 375 1.1E-49 T 14-10-2018 IPR023614 Porin domain superfamily TSH58p_10970 1b0353e295e2b41d44f04ea6a2fee372 390 Pfam PF13609 Gram-negative porin 10 366 1.7E-55 T 14-10-2018 TSH58p_18000 00efe08dc4bfb3f7cb81c7b7896883f5 137 Pfam PF09557 Domain of unknown function (DUF2382) 14 125 8.4E-14 T 14-10-2018 IPR019060 Domain of unknown function DUF2382 TSH58p_30250 b0b48fd836d5413a8317d49aefcd3e6d 294 SUPERFAMILY SSF46689 190 240 1.66E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_30250 b0b48fd836d5413a8317d49aefcd3e6d 294 SUPERFAMILY SSF46689 242 291 3.4E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_30250 b0b48fd836d5413a8317d49aefcd3e6d 294 Gene3D G3DSA:1.10.10.60 189 248 2.1E-17 T 14-10-2018 TSH58p_30250 b0b48fd836d5413a8317d49aefcd3e6d 294 SMART SM00342 206 289 1.4E-24 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TSH58p_30250 b0b48fd836d5413a8317d49aefcd3e6d 294 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 243 285 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 TSH58p_30250 b0b48fd836d5413a8317d49aefcd3e6d 294 Gene3D G3DSA:1.10.10.60 249 293 1.2E-10 T 14-10-2018 TSH58p_30250 b0b48fd836d5413a8317d49aefcd3e6d 294 Pfam PF12833 Helix-turn-helix domain 212 290 3.1E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TSH58p_21995 c716061bcf237b3c85f8f32244d22514 288 PRINTS PR01438 Universal stress protein signature 248 260 8.0E-10 T 14-10-2018 IPR006015 Universal stress protein A TSH58p_21995 c716061bcf237b3c85f8f32244d22514 288 PRINTS PR01438 Universal stress protein signature 3 21 8.0E-10 T 14-10-2018 IPR006015 Universal stress protein A TSH58p_21995 c716061bcf237b3c85f8f32244d22514 288 PRINTS PR01438 Universal stress protein signature 266 288 8.0E-10 T 14-10-2018 IPR006015 Universal stress protein A TSH58p_21995 c716061bcf237b3c85f8f32244d22514 288 Pfam PF00582 Universal stress protein family 234 287 1.5E-9 T 14-10-2018 IPR006016 UspA TSH58p_21995 c716061bcf237b3c85f8f32244d22514 288 SUPERFAMILY SSF52402 1 159 1.0E-8 T 14-10-2018 TSH58p_21995 c716061bcf237b3c85f8f32244d22514 288 SUPERFAMILY SSF52402 168 288 1.84E-21 T 14-10-2018 TSH58p_21995 c716061bcf237b3c85f8f32244d22514 288 Gene3D G3DSA:3.40.50.12370 5 288 6.0E-29 T 14-10-2018 TSH58p_15870 61884bf0975763537fe5e6c22e2ca364 190 Gene3D G3DSA:1.20.1290.10 67 190 1.5E-43 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TSH58p_15870 61884bf0975763537fe5e6c22e2ca364 190 Gene3D G3DSA:1.20.5.810 17 66 2.1E-24 T 14-10-2018 TSH58p_15870 61884bf0975763537fe5e6c22e2ca364 190 Pfam PF02627 Carboxymuconolactone decarboxylase family 50 104 8.5E-10 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TSH58p_15870 61884bf0975763537fe5e6c22e2ca364 190 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 65 113 5.9E-14 T 14-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TSH58p_15870 61884bf0975763537fe5e6c22e2ca364 190 TIGRFAM TIGR01926 peroxid_rel: uncharacterized peroxidase-related enzyme 9 183 1.7E-65 T 14-10-2018 IPR010195 Uncharacterised peroxidase-related TSH58p_15870 61884bf0975763537fe5e6c22e2ca364 190 SUPERFAMILY SSF69118 3 186 2.49E-57 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TSH58p_01155 c394c098c75468552b989c0c51d95bd6 326 Gene3D G3DSA:2.130.10.10 229 326 2.8E-22 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TSH58p_01155 c394c098c75468552b989c0c51d95bd6 326 Gene3D G3DSA:2.130.10.10 17 228 2.0E-52 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TSH58p_01155 c394c098c75468552b989c0c51d95bd6 326 TIGRFAM TIGR03866 PQQ_ABC_repeats: PQQ-dependent catabolism-associated beta-propeller protein 19 326 8.1E-150 T 14-10-2018 IPR022456 PQQ-dependent catabolism-associated beta-propeller protein TSH58p_01155 c394c098c75468552b989c0c51d95bd6 326 SUPERFAMILY SSF50974 12 324 7.19E-75 T 14-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 TSH58p_01155 c394c098c75468552b989c0c51d95bd6 326 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 28 65 1.0E-11 T 14-10-2018 IPR011964 YVTN beta-propeller repeat TSH58p_01155 c394c098c75468552b989c0c51d95bd6 326 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 284 324 1.2E-10 T 14-10-2018 IPR011964 YVTN beta-propeller repeat TSH58p_01155 c394c098c75468552b989c0c51d95bd6 326 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 108 149 1.5E-9 T 14-10-2018 IPR011964 YVTN beta-propeller repeat TSH58p_03960 da3403780738d4464f78e4846a00ab39 455 Gene3D G3DSA:2.130.10.10 95 455 1.2E-90 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TSH58p_03960 da3403780738d4464f78e4846a00ab39 455 SUPERFAMILY SSF50998 72 445 9.16E-82 T 14-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TSH58p_03960 da3403780738d4464f78e4846a00ab39 455 SMART SM00564 125 156 0.14 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSH58p_03960 da3403780738d4464f78e4846a00ab39 455 SMART SM00564 307 338 50.0 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSH58p_03960 da3403780738d4464f78e4846a00ab39 455 SMART SM00564 395 426 0.013 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSH58p_03960 da3403780738d4464f78e4846a00ab39 455 SMART SM00564 345 376 170.0 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSH58p_03960 da3403780738d4464f78e4846a00ab39 455 SMART SM00564 170 202 0.016 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSH58p_03960 da3403780738d4464f78e4846a00ab39 455 SMART SM00564 211 242 0.054 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSH58p_03960 da3403780738d4464f78e4846a00ab39 455 SMART SM00564 256 287 290.0 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSH58p_03960 da3403780738d4464f78e4846a00ab39 455 Pfam PF13360 PQQ-like domain 138 374 9.1E-64 T 14-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat TSH58p_03960 da3403780738d4464f78e4846a00ab39 455 Pfam PF13360 PQQ-like domain 393 454 3.9E-7 T 14-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat TSH58p_08875 0f6f28bef616b7745ed486cad102fdb7 457 Pfam PF09190 DALR domain 341 397 7.1E-16 T 14-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 TSH58p_08875 0f6f28bef616b7745ed486cad102fdb7 457 SMART SM00840 338 397 6.2E-20 T 14-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 TSH58p_08875 0f6f28bef616b7745ed486cad102fdb7 457 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 314 7.0E-122 T 14-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 TSH58p_08875 0f6f28bef616b7745ed486cad102fdb7 457 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 456 4.7E-157 T 14-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 TSH58p_08875 0f6f28bef616b7745ed486cad102fdb7 457 SUPERFAMILY SSF52374 4 312 3.22E-91 T 14-10-2018 TSH58p_08875 0f6f28bef616b7745ed486cad102fdb7 457 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 1.6E-31 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TSH58p_08875 0f6f28bef616b7745ed486cad102fdb7 457 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 1.6E-31 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TSH58p_08875 0f6f28bef616b7745ed486cad102fdb7 457 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 1.6E-31 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TSH58p_08875 0f6f28bef616b7745ed486cad102fdb7 457 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 1.6E-31 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TSH58p_08875 0f6f28bef616b7745ed486cad102fdb7 457 Gene3D G3DSA:3.40.50.620 1 306 5.6E-126 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_08875 0f6f28bef616b7745ed486cad102fdb7 457 SUPERFAMILY SSF47323 317 456 2.62E-33 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_08875 0f6f28bef616b7745ed486cad102fdb7 457 Gene3D G3DSA:1.20.120.640 307 457 1.3E-39 T 14-10-2018 TSH58p_08875 0f6f28bef616b7745ed486cad102fdb7 457 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 457 38.31 T 14-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 TSH58p_05770 71935de3c95fe2db0fec968fd1b84f1b 264 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 7 227 2.5E-100 T 14-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_05770 71935de3c95fe2db0fec968fd1b84f1b 264 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 4 226 41.609 T 14-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_05770 71935de3c95fe2db0fec968fd1b84f1b 264 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 159 183 - T 14-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 TSH58p_05770 71935de3c95fe2db0fec968fd1b84f1b 264 PRINTS PR00395 Ribosomal protein S2 signature 159 176 1.7E-40 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_05770 71935de3c95fe2db0fec968fd1b84f1b 264 PRINTS PR00395 Ribosomal protein S2 signature 39 48 1.7E-40 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_05770 71935de3c95fe2db0fec968fd1b84f1b 264 PRINTS PR00395 Ribosomal protein S2 signature 8 26 1.7E-40 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_05770 71935de3c95fe2db0fec968fd1b84f1b 264 PRINTS PR00395 Ribosomal protein S2 signature 89 106 1.7E-40 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_05770 71935de3c95fe2db0fec968fd1b84f1b 264 PRINTS PR00395 Ribosomal protein S2 signature 176 187 1.7E-40 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_05770 71935de3c95fe2db0fec968fd1b84f1b 264 PRINTS PR00395 Ribosomal protein S2 signature 197 211 1.7E-40 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_05770 71935de3c95fe2db0fec968fd1b84f1b 264 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 8 19 - T 14-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 TSH58p_05770 71935de3c95fe2db0fec968fd1b84f1b 264 SUPERFAMILY SSF52313 8 237 1.83E-92 T 14-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily TSH58p_05770 71935de3c95fe2db0fec968fd1b84f1b 264 Gene3D G3DSA:1.10.287.610 105 151 8.1E-89 T 14-10-2018 TSH58p_05770 71935de3c95fe2db0fec968fd1b84f1b 264 Gene3D G3DSA:3.40.50.10490 10 219 8.1E-89 T 14-10-2018 TSH58p_05770 71935de3c95fe2db0fec968fd1b84f1b 264 Pfam PF00318 Ribosomal protein S2 11 225 5.4E-94 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_11015 f967665dc8258284e466dc479f02065d 622 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 270 284 - T 14-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 TSH58p_11015 f967665dc8258284e466dc479f02065d 622 Pfam PF13932 GidA associated domain 399 609 1.0E-70 T 14-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 TSH58p_11015 f967665dc8258284e466dc479f02065d 622 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 4 615 7.4E-254 T 14-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 TSH58p_11015 f967665dc8258284e466dc479f02065d 622 SMART SM01228 540 611 5.3E-37 T 14-10-2018 TSH58p_11015 f967665dc8258284e466dc479f02065d 622 Gene3D G3DSA:1.10.150.570 563 617 8.7E-19 T 14-10-2018 TSH58p_11015 f967665dc8258284e466dc479f02065d 622 Pfam PF01134 Glucose inhibited division protein A 5 393 2.8E-167 T 14-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 TSH58p_11015 f967665dc8258284e466dc479f02065d 622 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 5.3E-6 T 14-10-2018 TSH58p_11015 f967665dc8258284e466dc479f02065d 622 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 355 376 5.3E-6 T 14-10-2018 TSH58p_11015 f967665dc8258284e466dc479f02065d 622 Gene3D G3DSA:3.50.50.60 295 456 1.3E-56 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_11015 f967665dc8258284e466dc479f02065d 622 Gene3D G3DSA:3.50.50.60 1 217 4.3E-93 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_11015 f967665dc8258284e466dc479f02065d 622 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 2 618 41.966 T 14-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 TSH58p_11015 f967665dc8258284e466dc479f02065d 622 SUPERFAMILY SSF51905 2 258 4.91E-49 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_11015 f967665dc8258284e466dc479f02065d 622 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 365 388 - T 14-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 TSH58p_16835 74d33738086fc6da8984db523b0dd6c0 336 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 32 287 1.3E-101 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 TSH58p_16835 74d33738086fc6da8984db523b0dd6c0 336 PIRSF PIRSF006470 1 332 1.0E-136 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 TSH58p_16835 74d33738086fc6da8984db523b0dd6c0 336 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 32 315 1.3E-107 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 TSH58p_16835 74d33738086fc6da8984db523b0dd6c0 336 Gene3D G3DSA:3.40.190.170 27 329 6.6E-104 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily TSH58p_27165 26ab2e152f9c4e9180a98bc6714f331c 136 Pfam PF00072 Response regulator receiver domain 9 123 1.0E-18 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_27165 26ab2e152f9c4e9180a98bc6714f331c 136 SUPERFAMILY SSF52172 6 128 2.28E-27 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_27165 26ab2e152f9c4e9180a98bc6714f331c 136 SMART SM00448 7 123 1.4E-17 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_27165 26ab2e152f9c4e9180a98bc6714f331c 136 Gene3D G3DSA:3.40.50.2300 6 133 1.2E-27 T 14-10-2018 TSH58p_01580 828cc0f86b484d41a872b0730c2b473e 122 Pfam PF12680 SnoaL-like domain 9 110 1.3E-12 T 14-10-2018 IPR037401 SnoaL-like domain TSH58p_01580 828cc0f86b484d41a872b0730c2b473e 122 SUPERFAMILY SSF54427 1 116 1.47E-34 T 14-10-2018 IPR032710 NTF2-like domain superfamily TSH58p_01580 828cc0f86b484d41a872b0730c2b473e 122 Gene3D G3DSA:3.10.450.50 1 118 1.1E-39 T 14-10-2018 TSH58p_12460 3dee6e7fa848be72a1b207be1c2f1b84 147 ProSitePatterns PS00893 Nudix box signature. 53 74 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TSH58p_12460 3dee6e7fa848be72a1b207be1c2f1b84 147 Pfam PF14815 NUDIX domain 24 140 4.2E-21 T 14-10-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 TSH58p_12460 3dee6e7fa848be72a1b207be1c2f1b84 147 PRINTS PR00502 NUDIX hydrolase family signature 48 62 3.3E-9 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TSH58p_12460 3dee6e7fa848be72a1b207be1c2f1b84 147 PRINTS PR00502 NUDIX hydrolase family signature 62 77 3.3E-9 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TSH58p_12460 3dee6e7fa848be72a1b207be1c2f1b84 147 Gene3D G3DSA:3.90.79.10 14 147 2.0E-43 T 14-10-2018 TSH58p_12460 3dee6e7fa848be72a1b207be1c2f1b84 147 SUPERFAMILY SSF55811 16 144 2.71E-41 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TSH58p_19360 4bfcabfb7f6ff5e67069f23a273fa767 361 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 1 24 4.3E-5 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal TSH58p_19360 4bfcabfb7f6ff5e67069f23a273fa767 361 Gene3D G3DSA:3.40.190.10 152 322 1.6E-125 T 14-10-2018 TSH58p_19360 4bfcabfb7f6ff5e67069f23a273fa767 361 Gene3D G3DSA:3.40.190.170 32 336 1.6E-125 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily TSH58p_19360 4bfcabfb7f6ff5e67069f23a273fa767 361 SUPERFAMILY SSF53850 140 306 1.17E-6 T 14-10-2018 TSH58p_19360 4bfcabfb7f6ff5e67069f23a273fa767 361 PIRSF PIRSF039026 1 356 4.3E-124 T 14-10-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like TSH58p_19360 4bfcabfb7f6ff5e67069f23a273fa767 361 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 41 320 8.1E-60 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 TSH58p_25525 ef628ff08a3577582b37cc272ddef3f6 293 Gene3D G3DSA:1.10.10.2830 110 223 9.2E-23 T 14-10-2018 TSH58p_25525 ef628ff08a3577582b37cc272ddef3f6 293 SUPERFAMILY SSF110849 34 159 1.17E-24 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily TSH58p_25525 ef628ff08a3577582b37cc272ddef3f6 293 Pfam PF02195 ParB-like nuclease domain 36 121 4.1E-21 T 14-10-2018 IPR003115 ParB/Sulfiredoxin TSH58p_25525 ef628ff08a3577582b37cc272ddef3f6 293 SMART SM00470 35 122 7.0E-28 T 14-10-2018 IPR003115 ParB/Sulfiredoxin TSH58p_25525 ef628ff08a3577582b37cc272ddef3f6 293 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 34 185 2.8E-43 T 14-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 TSH58p_25525 ef628ff08a3577582b37cc272ddef3f6 293 Gene3D G3DSA:3.90.1530.30 48 109 7.6E-23 T 14-10-2018 TSH58p_02790 54096b6da2a1d74efef898f79c808f33 937 Pfam PF16841 Ca-dependent carbohydrate-binding module xylan-binding 742 833 1.8E-29 T 14-10-2018 IPR031768 Carbohydrate binding module, xylan-binding domain MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSH58p_02790 54096b6da2a1d74efef898f79c808f33 937 Pfam PF16841 Ca-dependent carbohydrate-binding module xylan-binding 605 696 1.2E-30 T 14-10-2018 IPR031768 Carbohydrate binding module, xylan-binding domain MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSH58p_02790 54096b6da2a1d74efef898f79c808f33 937 Pfam PF13229 Right handed beta helix region 189 358 1.2E-12 T 14-10-2018 IPR039448 Right handed beta helix domain TSH58p_02790 54096b6da2a1d74efef898f79c808f33 937 Gene3D G3DSA:2.60.60.40 739 853 3.6E-9 T 14-10-2018 TSH58p_02790 54096b6da2a1d74efef898f79c808f33 937 Gene3D G3DSA:2.60.60.40 602 714 1.1E-9 T 14-10-2018 TSH58p_02790 54096b6da2a1d74efef898f79c808f33 937 SUPERFAMILY SSF51126 19 461 1.13E-23 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor TSH58p_02315 3d58560242becbc01257f211a8883aa4 192 SMART SM00867 26 190 3.7E-70 T 14-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like TSH58p_02315 3d58560242becbc01257f211a8883aa4 192 Pfam PF04264 YceI-like domain 27 188 5.1E-48 T 14-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like TSH58p_02315 3d58560242becbc01257f211a8883aa4 192 Gene3D G3DSA:2.40.128.110 25 192 5.3E-57 T 14-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily TSH58p_02315 3d58560242becbc01257f211a8883aa4 192 SUPERFAMILY SSF101874 24 191 5.49E-57 T 14-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily TSH58p_01560 668529806a52f498d4c77eb382e41c3c 224 Gene3D G3DSA:1.10.10.10 9 77 7.9E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_01560 668529806a52f498d4c77eb382e41c3c 224 Pfam PF07729 FCD domain 85 209 5.1E-22 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_01560 668529806a52f498d4c77eb382e41c3c 224 SUPERFAMILY SSF48008 83 220 8.37E-23 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_01560 668529806a52f498d4c77eb382e41c3c 224 SMART SM00895 85 211 7.4E-15 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_01560 668529806a52f498d4c77eb382e41c3c 224 SMART SM00345 17 75 2.4E-8 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_01560 668529806a52f498d4c77eb382e41c3c 224 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 75 1.5E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_01560 668529806a52f498d4c77eb382e41c3c 224 Gene3D G3DSA:1.20.120.530 78 222 4.2E-26 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_01560 668529806a52f498d4c77eb382e41c3c 224 SUPERFAMILY SSF46785 8 79 3.81E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_14745 b9cb9fe52f03a3d53bde5508a6011b2f 508 SUPERFAMILY SSF50475 3 334 3.92E-115 T 14-10-2018 TSH58p_14745 b9cb9fe52f03a3d53bde5508a6011b2f 508 Gene3D G3DSA:3.40.1670.10 349 466 1.2E-51 T 14-10-2018 TSH58p_14745 b9cb9fe52f03a3d53bde5508a6011b2f 508 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 467 2.1E-158 T 14-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 TSH58p_14745 b9cb9fe52f03a3d53bde5508a6011b2f 508 SUPERFAMILY SSF143968 335 499 1.19E-67 T 14-10-2018 TSH58p_14745 b9cb9fe52f03a3d53bde5508a6011b2f 508 Gene3D G3DSA:1.20.5.570 467 504 2.5E-6 T 14-10-2018 TSH58p_14745 b9cb9fe52f03a3d53bde5508a6011b2f 508 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 10 443 4.7E-168 T 14-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 TSH58p_32025 4d5b1c41209a92ac25a913b0d4eb8e81 449 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 182 238 - T 14-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_32025 4d5b1c41209a92ac25a913b0d4eb8e81 449 Gene3D G3DSA:1.20.210.10 1 441 4.0E-130 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_32025 4d5b1c41209a92ac25a913b0d4eb8e81 449 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 7 416 5.4E-81 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_32025 4d5b1c41209a92ac25a913b0d4eb8e81 449 SUPERFAMILY SSF81442 4 442 6.93E-91 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_08185 6c826f1d0a2c1c1346ad939dedd52fd1 547 PRINTS PR00662 Glucose-6-phosphate isomerase signature 336 357 2.9E-58 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_08185 6c826f1d0a2c1c1346ad939dedd52fd1 547 PRINTS PR00662 Glucose-6-phosphate isomerase signature 463 481 2.9E-58 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_08185 6c826f1d0a2c1c1346ad939dedd52fd1 547 PRINTS PR00662 Glucose-6-phosphate isomerase signature 147 166 2.9E-58 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_08185 6c826f1d0a2c1c1346ad939dedd52fd1 547 PRINTS PR00662 Glucose-6-phosphate isomerase signature 481 495 2.9E-58 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_08185 6c826f1d0a2c1c1346ad939dedd52fd1 547 PRINTS PR00662 Glucose-6-phosphate isomerase signature 259 277 2.9E-58 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_08185 6c826f1d0a2c1c1346ad939dedd52fd1 547 PRINTS PR00662 Glucose-6-phosphate isomerase signature 495 508 2.9E-58 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_08185 6c826f1d0a2c1c1346ad939dedd52fd1 547 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 495 512 - T 14-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_08185 6c826f1d0a2c1c1346ad939dedd52fd1 547 Gene3D G3DSA:1.10.1390.10 505 547 1.6E-19 T 14-10-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_08185 6c826f1d0a2c1c1346ad939dedd52fd1 547 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 43 522 42.72 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_08185 6c826f1d0a2c1c1346ad939dedd52fd1 547 Gene3D G3DSA:3.40.50.10490 10 504 5.7E-241 T 14-10-2018 TSH58p_08185 6c826f1d0a2c1c1346ad939dedd52fd1 547 SUPERFAMILY SSF53697 4 546 1.84E-232 T 14-10-2018 TSH58p_08185 6c826f1d0a2c1c1346ad939dedd52fd1 547 Gene3D G3DSA:3.40.50.10490 95 289 5.7E-241 T 14-10-2018 TSH58p_08185 6c826f1d0a2c1c1346ad939dedd52fd1 547 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 263 276 - T 14-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_08185 6c826f1d0a2c1c1346ad939dedd52fd1 547 Pfam PF00342 Phosphoglucose isomerase 49 540 2.3E-241 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_30925 cfd31b15633880adf4cc88a3d2ab02b4 521 SUPERFAMILY SSF53649 4 446 1.03E-117 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 TSH58p_30925 cfd31b15633880adf4cc88a3d2ab02b4 521 Pfam PF12411 Choline sulfatase enzyme C terminal 456 507 4.2E-15 T 14-10-2018 IPR025863 Choline sulfatase enzyme C-terminal domain TSH58p_30925 cfd31b15633880adf4cc88a3d2ab02b4 521 Pfam PF00884 Sulfatase 5 351 3.1E-60 T 14-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 TSH58p_30925 cfd31b15633880adf4cc88a3d2ab02b4 521 Gene3D G3DSA:3.40.720.10 4 467 7.2E-122 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 TSH58p_30925 cfd31b15633880adf4cc88a3d2ab02b4 521 TIGRFAM TIGR03417 chol_sulfatase: choline-sulfatase 5 509 2.1E-205 T 14-10-2018 IPR017785 Choline-sulfatase TSH58p_30215 6c0c89db562d583788798792df9d2d73 401 Pfam PF02803 Thiolase, C-terminal domain 278 399 4.4E-43 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 TSH58p_30215 6c0c89db562d583788798792df9d2d73 401 PIRSF PIRSF000429 1 401 2.6E-110 T 14-10-2018 IPR002155 Thiolase GO:0016747 TSH58p_30215 6c0c89db562d583788798792df9d2d73 401 ProSitePatterns PS00099 Thiolases active site. 381 394 - T 14-10-2018 IPR020610 Thiolase, active site GO:0016747 TSH58p_30215 6c0c89db562d583788798792df9d2d73 401 SUPERFAMILY SSF53901 279 399 2.33E-42 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_30215 6c0c89db562d583788798792df9d2d73 401 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 9 398 8.2E-121 T 14-10-2018 IPR002155 Thiolase GO:0016747 TSH58p_30215 6c0c89db562d583788798792df9d2d73 401 Gene3D G3DSA:3.40.47.10 134 396 1.7E-137 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_30215 6c0c89db562d583788798792df9d2d73 401 Gene3D G3DSA:3.40.47.10 9 283 1.7E-137 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_30215 6c0c89db562d583788798792df9d2d73 401 SUPERFAMILY SSF53901 7 277 9.02E-72 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_30215 6c0c89db562d583788798792df9d2d73 401 Pfam PF00108 Thiolase, N-terminal domain 7 269 7.1E-78 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 TSH58p_30570 e860bba358bc12d45eb8b96f14f108b9 279 PIRSF PIRSF002854 4 279 2.0E-78 T 14-10-2018 IPR004872 Lipoprotein NlpA family TSH58p_30570 e860bba358bc12d45eb8b96f14f108b9 279 SUPERFAMILY SSF53850 40 279 4.34E-66 T 14-10-2018 TSH58p_30570 e860bba358bc12d45eb8b96f14f108b9 279 Gene3D G3DSA:3.40.190.10 121 229 1.6E-75 T 14-10-2018 TSH58p_30570 e860bba358bc12d45eb8b96f14f108b9 279 Pfam PF03180 NLPA lipoprotein 40 279 5.5E-71 T 14-10-2018 IPR004872 Lipoprotein NlpA family TSH58p_30570 e860bba358bc12d45eb8b96f14f108b9 279 Gene3D G3DSA:3.40.190.10 41 273 1.6E-75 T 14-10-2018 TSH58p_08790 eaea5724b8b9a6ca08e8c8034e96dbbc 204 Pfam PF01479 S4 domain 93 140 3.4E-17 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_08790 eaea5724b8b9a6ca08e8c8034e96dbbc 204 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 204 33.008 T 14-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 TSH58p_08790 eaea5724b8b9a6ca08e8c8034e96dbbc 204 SMART SM01390 3 92 2.4E-40 T 14-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 TSH58p_08790 eaea5724b8b9a6ca08e8c8034e96dbbc 204 SMART SM00363 93 157 2.4E-16 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_08790 eaea5724b8b9a6ca08e8c8034e96dbbc 204 SUPERFAMILY SSF55174 7 204 8.77E-62 T 14-10-2018 TSH58p_08790 eaea5724b8b9a6ca08e8c8034e96dbbc 204 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 5 204 6.5E-75 T 14-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 TSH58p_08790 eaea5724b8b9a6ca08e8c8034e96dbbc 204 Gene3D G3DSA:3.10.290.10 92 187 4.8E-69 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TSH58p_08790 eaea5724b8b9a6ca08e8c8034e96dbbc 204 Gene3D G3DSA:1.10.1050.10 7 204 4.8E-69 T 14-10-2018 TSH58p_08790 eaea5724b8b9a6ca08e8c8034e96dbbc 204 ProSitePatterns PS00632 Ribosomal protein S4 signature. 91 115 - T 14-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_08790 eaea5724b8b9a6ca08e8c8034e96dbbc 204 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 5 92 8.3E-27 T 14-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 TSH58p_13860 08e715b7fe07a665cbba386b7dc43022 246 Pfam PF00005 ABC transporter 22 165 7.6E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_13860 08e715b7fe07a665cbba386b7dc43022 246 TIGRFAM TIGR03864 PQQ_ABC_ATP: ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system 5 241 7.0E-106 T 14-10-2018 IPR022467 ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system TSH58p_13860 08e715b7fe07a665cbba386b7dc43022 246 SUPERFAMILY SSF52540 4 226 5.09E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_13860 08e715b7fe07a665cbba386b7dc43022 246 SMART SM00382 31 214 2.9E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_13860 08e715b7fe07a665cbba386b7dc43022 246 Gene3D G3DSA:3.40.50.300 1 244 1.7E-67 T 14-10-2018 TSH58p_26650 43a1adf8485ad1062d579f86fbeb5ed5 406 Gene3D G3DSA:3.40.50.300 1 239 8.9E-58 T 14-10-2018 TSH58p_26650 43a1adf8485ad1062d579f86fbeb5ed5 406 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_26650 43a1adf8485ad1062d579f86fbeb5ed5 406 SMART SM00382 27 228 1.0E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_26650 43a1adf8485ad1062d579f86fbeb5ed5 406 Gene3D G3DSA:2.40.50.140 301 369 7.9E-22 T 14-10-2018 TSH58p_26650 43a1adf8485ad1062d579f86fbeb5ed5 406 SUPERFAMILY SSF52540 3 259 2.66E-78 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_26650 43a1adf8485ad1062d579f86fbeb5ed5 406 Gene3D G3DSA:2.40.50.940 240 378 7.9E-22 T 14-10-2018 TSH58p_26650 43a1adf8485ad1062d579f86fbeb5ed5 406 Pfam PF00005 ABC transporter 19 178 4.4E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_26650 43a1adf8485ad1062d579f86fbeb5ed5 406 SUPERFAMILY SSF50331 253 384 1.17E-17 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSH58p_14370 9493cfbe18c8144f3ba701b470030a44 166 Pfam PF02381 MraZ protein, putative antitoxin-like 87 134 1.3E-6 T 14-10-2018 IPR020603 MraZ domain TSH58p_14370 9493cfbe18c8144f3ba701b470030a44 166 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 166 29.111 T 14-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 TSH58p_14370 9493cfbe18c8144f3ba701b470030a44 166 Gene3D G3DSA:2.40.330.20 1 145 6.7E-27 T 14-10-2018 IPR038619 MraZ superfamily TSH58p_14370 9493cfbe18c8144f3ba701b470030a44 166 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 4 128 2.0E-8 T 14-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 TSH58p_14370 9493cfbe18c8144f3ba701b470030a44 166 SUPERFAMILY SSF89447 1 137 6.06E-31 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily TSH58p_05670 530dc1bae48c403f1eefff60cca35610 470 Gene3D G3DSA:1.10.10.350 368 465 2.6E-27 T 14-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TSH58p_05670 530dc1bae48c403f1eefff60cca35610 470 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 9 20 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_05670 530dc1bae48c403f1eefff60cca35610 470 SUPERFAMILY SSF48163 300 464 9.42E-38 T 14-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TSH58p_05670 530dc1bae48c403f1eefff60cca35610 470 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 3 463 1.0E-153 T 14-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TSH58p_05670 530dc1bae48c403f1eefff60cca35610 470 SUPERFAMILY SSF52374 3 299 2.68E-109 T 14-10-2018 TSH58p_05670 530dc1bae48c403f1eefff60cca35610 470 Gene3D G3DSA:3.40.50.620 1 315 1.9E-129 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_05670 530dc1bae48c403f1eefff60cca35610 470 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 3 305 5.3E-93 T 14-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 TSH58p_05670 530dc1bae48c403f1eefff60cca35610 470 PRINTS PR00987 Glutamyl-tRNA synthetase signature 20 31 3.1E-26 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSH58p_05670 530dc1bae48c403f1eefff60cca35610 470 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 3.1E-26 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSH58p_05670 530dc1bae48c403f1eefff60cca35610 470 PRINTS PR00987 Glutamyl-tRNA synthetase signature 180 190 3.1E-26 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSH58p_05670 530dc1bae48c403f1eefff60cca35610 470 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 3.1E-26 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSH58p_05670 530dc1bae48c403f1eefff60cca35610 470 PRINTS PR00987 Glutamyl-tRNA synthetase signature 196 204 3.1E-26 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSH58p_05670 530dc1bae48c403f1eefff60cca35610 470 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 2 465 31.308 T 14-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TSH58p_05265 ebff09636cf14364dcc47cf141018a57 142 ProSitePatterns PS01117 MarR-type HTH domain signature. 57 91 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site TSH58p_05265 ebff09636cf14364dcc47cf141018a57 142 SMART SM00347 18 118 8.9E-18 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_05265 ebff09636cf14364dcc47cf141018a57 142 SUPERFAMILY SSF46785 3 133 4.34E-30 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_05265 ebff09636cf14364dcc47cf141018a57 142 Pfam PF12802 MarR family 23 82 1.2E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_05265 ebff09636cf14364dcc47cf141018a57 142 Gene3D G3DSA:1.10.10.10 2 135 9.0E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_05265 ebff09636cf14364dcc47cf141018a57 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 59 74 1.3E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_05265 ebff09636cf14364dcc47cf141018a57 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 108 128 1.3E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_05265 ebff09636cf14364dcc47cf141018a57 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 78 94 1.3E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_00850 d26c8e2fb09b2c2ac05d616ccff52ab9 161 Gene3D G3DSA:1.10.490.10 19 137 1.9E-39 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 TSH58p_00850 d26c8e2fb09b2c2ac05d616ccff52ab9 161 Pfam PF01152 Bacterial-like globin 24 110 1.2E-4 T 14-10-2018 IPR001486 Truncated hemoglobin GO:0019825 TSH58p_00850 d26c8e2fb09b2c2ac05d616ccff52ab9 161 SUPERFAMILY SSF46458 23 131 4.4E-29 T 14-10-2018 IPR009050 Globin-like superfamily TSH58p_24285 bd5bd71ebb5b1a9ff272308cf119538b 480 PRINTS PR00149 Fumarate lyase superfamily signature 125 143 5.6E-30 T 14-10-2018 IPR000362 Fumarate lyase family TSH58p_24285 bd5bd71ebb5b1a9ff272308cf119538b 480 PRINTS PR00149 Fumarate lyase superfamily signature 170 188 5.6E-30 T 14-10-2018 IPR000362 Fumarate lyase family TSH58p_24285 bd5bd71ebb5b1a9ff272308cf119538b 480 PRINTS PR00149 Fumarate lyase superfamily signature 254 281 5.6E-30 T 14-10-2018 IPR000362 Fumarate lyase family TSH58p_24285 bd5bd71ebb5b1a9ff272308cf119538b 480 PRINTS PR00149 Fumarate lyase superfamily signature 298 314 5.6E-30 T 14-10-2018 IPR000362 Fumarate lyase family TSH58p_24285 bd5bd71ebb5b1a9ff272308cf119538b 480 TIGRFAM TIGR00838 argH: argininosuccinate lyase 26 478 5.2E-183 T 14-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TSH58p_24285 bd5bd71ebb5b1a9ff272308cf119538b 480 Pfam PF14698 Argininosuccinate lyase C-terminal 386 454 3.4E-23 T 14-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TSH58p_24285 bd5bd71ebb5b1a9ff272308cf119538b 480 PRINTS PR00145 Argininosuccinate lyase family signature 298 314 7.9E-68 T 14-10-2018 TSH58p_24285 bd5bd71ebb5b1a9ff272308cf119538b 480 PRINTS PR00145 Argininosuccinate lyase family signature 254 278 7.9E-68 T 14-10-2018 TSH58p_24285 bd5bd71ebb5b1a9ff272308cf119538b 480 PRINTS PR00145 Argininosuccinate lyase family signature 165 185 7.9E-68 T 14-10-2018 TSH58p_24285 bd5bd71ebb5b1a9ff272308cf119538b 480 PRINTS PR00145 Argininosuccinate lyase family signature 216 232 7.9E-68 T 14-10-2018 TSH58p_24285 bd5bd71ebb5b1a9ff272308cf119538b 480 PRINTS PR00145 Argininosuccinate lyase family signature 333 352 7.9E-68 T 14-10-2018 TSH58p_24285 bd5bd71ebb5b1a9ff272308cf119538b 480 PRINTS PR00145 Argininosuccinate lyase family signature 124 146 7.9E-68 T 14-10-2018 TSH58p_24285 bd5bd71ebb5b1a9ff272308cf119538b 480 Gene3D G3DSA:1.10.40.30 383 456 5.4E-189 T 14-10-2018 TSH58p_24285 bd5bd71ebb5b1a9ff272308cf119538b 480 SUPERFAMILY SSF48557 26 478 2.04E-148 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 TSH58p_24285 bd5bd71ebb5b1a9ff272308cf119538b 480 Pfam PF00206 Lyase 31 323 4.6E-81 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal TSH58p_24285 bd5bd71ebb5b1a9ff272308cf119538b 480 Hamap MF_00006 Argininosuccinate lyase [argH]. 25 477 42.247 T 14-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TSH58p_24285 bd5bd71ebb5b1a9ff272308cf119538b 480 Gene3D G3DSA:1.10.275.10 48 252 5.4E-189 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal TSH58p_24285 bd5bd71ebb5b1a9ff272308cf119538b 480 Gene3D G3DSA:1.20.200.10 142 471 5.4E-189 T 14-10-2018 TSH58p_24285 bd5bd71ebb5b1a9ff272308cf119538b 480 ProSitePatterns PS00163 Fumarate lyases signature. 298 307 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 TSH58p_20150 1b417d3e5636c53b73bc8a7ca76a1675 97 Pfam PF03927 NapD protein 4 78 3.1E-24 T 14-10-2018 IPR005623 Chaperone NapD, nitrate reductase assembly TSH58p_20150 1b417d3e5636c53b73bc8a7ca76a1675 97 Hamap MF_02200 Chaperone NapD [napD]. 4 79 17.827 T 14-10-2018 IPR005623 Chaperone NapD, nitrate reductase assembly TSH58p_20150 1b417d3e5636c53b73bc8a7ca76a1675 97 Gene3D G3DSA:3.30.70.920 4 72 2.4E-16 T 14-10-2018 TSH58p_15130 6f7d33f2947c624a1cdb1a4c22e699c5 1389 Gene3D G3DSA:2.40.50.100 938 1012 5.0E-23 T 14-10-2018 TSH58p_15130 6f7d33f2947c624a1cdb1a4c22e699c5 1389 SMART SM00663 236 515 4.1E-185 T 14-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_15130 6f7d33f2947c624a1cdb1a4c22e699c5 1389 Pfam PF04998 RNA polymerase Rpb1, domain 5 756 1303 7.1E-76 T 14-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_15130 6f7d33f2947c624a1cdb1a4c22e699c5 1389 Gene3D G3DSA:1.10.150.390 1304 1366 7.6E-28 T 14-10-2018 TSH58p_15130 6f7d33f2947c624a1cdb1a4c22e699c5 1389 Pfam PF00623 RNA polymerase Rpb1, domain 2 345 393 6.4E-8 T 14-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_15130 6f7d33f2947c624a1cdb1a4c22e699c5 1389 Pfam PF00623 RNA polymerase Rpb1, domain 2 394 486 8.2E-27 T 14-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_15130 6f7d33f2947c624a1cdb1a4c22e699c5 1389 Gene3D G3DSA:1.10.40.90 375 417 4.4E-22 T 14-10-2018 TSH58p_15130 6f7d33f2947c624a1cdb1a4c22e699c5 1389 Gene3D G3DSA:1.10.274.100 491 560 2.5E-23 T 14-10-2018 TSH58p_15130 6f7d33f2947c624a1cdb1a4c22e699c5 1389 Pfam PF04983 RNA polymerase Rpb1, domain 3 490 643 9.9E-28 T 14-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_15130 6f7d33f2947c624a1cdb1a4c22e699c5 1389 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 10 1365 18.965 T 14-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_15130 6f7d33f2947c624a1cdb1a4c22e699c5 1389 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 19 1010 0.0 T 14-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_15130 6f7d33f2947c624a1cdb1a4c22e699c5 1389 Gene3D G3DSA:2.40.50.100 1013 1114 2.9E-27 T 14-10-2018 TSH58p_15130 6f7d33f2947c624a1cdb1a4c22e699c5 1389 Pfam PF05000 RNA polymerase Rpb1, domain 4 672 752 1.2E-16 T 14-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_15130 6f7d33f2947c624a1cdb1a4c22e699c5 1389 Pfam PF04997 RNA polymerase Rpb1, domain 1 15 343 1.5E-88 T 14-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_15130 6f7d33f2947c624a1cdb1a4c22e699c5 1389 Gene3D G3DSA:1.10.132.30 640 780 7.3E-64 T 14-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_15130 6f7d33f2947c624a1cdb1a4c22e699c5 1389 SUPERFAMILY SSF64484 15 1351 0.0 T 14-10-2018 TSH58p_15130 6f7d33f2947c624a1cdb1a4c22e699c5 1389 Gene3D G3DSA:1.10.1790.20 1123 1302 4.1E-68 T 14-10-2018 TSH58p_15130 6f7d33f2947c624a1cdb1a4c22e699c5 1389 Gene3D G3DSA:2.40.50.100 1139 1203 4.1E-68 T 14-10-2018 TSH58p_15130 6f7d33f2947c624a1cdb1a4c22e699c5 1389 Gene3D G3DSA:1.10.274.100 561 639 1.4E-14 T 14-10-2018 TSH58p_14565 d185aabcda5d9e68dba81890acd2bbf8 427 Gene3D G3DSA:3.20.20.370 200 400 3.7E-58 T 14-10-2018 TSH58p_14565 d185aabcda5d9e68dba81890acd2bbf8 427 Pfam PF01522 Polysaccharide deacetylase 211 321 1.2E-29 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 TSH58p_14565 d185aabcda5d9e68dba81890acd2bbf8 427 SUPERFAMILY SSF88713 210 393 5.34E-58 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TSH58p_07880 294482acc0616cbb752272332b07ff54 271 Gene3D G3DSA:3.40.50.300 1 259 4.9E-70 T 14-10-2018 TSH58p_07880 294482acc0616cbb752272332b07ff54 271 Pfam PF13614 AAA domain 2 165 6.8E-21 T 14-10-2018 IPR025669 AAA domain TSH58p_07880 294482acc0616cbb752272332b07ff54 271 SUPERFAMILY SSF52540 3 267 3.02E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_07880 294482acc0616cbb752272332b07ff54 271 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 3 267 5.2E-108 T 14-10-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 TSH58p_07880 294482acc0616cbb752272332b07ff54 271 PIRSF PIRSF003092 1 271 6.8E-87 T 14-10-2018 IPR025501 ATP binding protein MinD TSH58p_30265 046f84606ee898625adce20282488b32 298 Gene3D G3DSA:3.40.50.1980 30 117 2.7E-19 T 14-10-2018 TSH58p_30265 046f84606ee898625adce20282488b32 298 SUPERFAMILY SSF53807 32 289 7.06E-48 T 14-10-2018 TSH58p_30265 046f84606ee898625adce20282488b32 298 Pfam PF01497 Periplasmic binding protein 34 268 5.6E-21 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain TSH58p_30265 046f84606ee898625adce20282488b32 298 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 181 196 4.4E-9 T 14-10-2018 TSH58p_30265 046f84606ee898625adce20282488b32 298 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 205 223 4.4E-9 T 14-10-2018 TSH58p_30265 046f84606ee898625adce20282488b32 298 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 51 69 4.4E-9 T 14-10-2018 TSH58p_30265 046f84606ee898625adce20282488b32 298 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 270 283 4.4E-9 T 14-10-2018 TSH58p_30265 046f84606ee898625adce20282488b32 298 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 82 97 4.4E-9 T 14-10-2018 TSH58p_30265 046f84606ee898625adce20282488b32 298 Gene3D G3DSA:3.40.50.1980 121 291 3.2E-51 T 14-10-2018 TSH58p_15560 d1069764fb953b6ffb6bd289f4069cb6 485 Pfam PF12801 4Fe-4S binding domain 95 135 1.1E-11 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_15560 d1069764fb953b6ffb6bd289f4069cb6 485 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 362 485 7.1E-28 T 14-10-2018 IPR032879 FixG, C-terminal immunoglobulin-like domain TSH58p_15560 d1069764fb953b6ffb6bd289f4069cb6 485 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 273 284 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_15560 d1069764fb953b6ffb6bd289f4069cb6 485 Pfam PF13746 4Fe-4S dicluster domain 217 325 4.0E-39 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_15560 d1069764fb953b6ffb6bd289f4069cb6 485 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 34 482 1.6E-151 T 14-10-2018 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021|GO:0055114 TSH58p_15560 d1069764fb953b6ffb6bd289f4069cb6 485 Gene3D G3DSA:2.60.40.10 362 484 2.8E-18 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_15560 d1069764fb953b6ffb6bd289f4069cb6 485 Gene3D G3DSA:3.30.70.20 214 291 4.3E-5 T 14-10-2018 TSH58p_15560 d1069764fb953b6ffb6bd289f4069cb6 485 SUPERFAMILY SSF54862 103 334 4.6E-27 T 14-10-2018 TSH58p_21400 9bd106741d4962c1a40b5e8444dc615e 406 Pfam PF12697 Alpha/beta hydrolase family 152 368 6.3E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_21400 9bd106741d4962c1a40b5e8444dc615e 406 Gene3D G3DSA:1.20.1440.110 12 121 2.0E-23 T 14-10-2018 TSH58p_21400 9bd106741d4962c1a40b5e8444dc615e 406 Gene3D G3DSA:3.40.50.1820 125 404 2.6E-56 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_21400 9bd106741d4962c1a40b5e8444dc615e 406 SUPERFAMILY SSF53474 17 401 4.09E-46 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_29450 cbe5d96f231adfe113204884afa7a4c0 692 SUPERFAMILY SSF55073 266 425 4.63E-30 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_29450 cbe5d96f231adfe113204884afa7a4c0 692 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 138 256 2.2E-26 T 14-10-2018 IPR000014 PAS domain TSH58p_29450 cbe5d96f231adfe113204884afa7a4c0 692 SMART SM00052 433 679 1.8E-101 T 14-10-2018 IPR001633 EAL domain TSH58p_29450 cbe5d96f231adfe113204884afa7a4c0 692 Gene3D G3DSA:3.30.450.20 135 251 1.5E-30 T 14-10-2018 TSH58p_29450 cbe5d96f231adfe113204884afa7a4c0 692 Pfam PF08448 PAS fold 18 122 4.0E-9 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_29450 cbe5d96f231adfe113204884afa7a4c0 692 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 260 421 1.2E-20 T 14-10-2018 IPR000160 GGDEF domain TSH58p_29450 cbe5d96f231adfe113204884afa7a4c0 692 Gene3D G3DSA:3.30.450.20 9 127 1.6E-11 T 14-10-2018 TSH58p_29450 cbe5d96f231adfe113204884afa7a4c0 692 SUPERFAMILY SSF55785 12 120 1.43E-13 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_29450 cbe5d96f231adfe113204884afa7a4c0 692 SMART SM00086 81 122 7.4 T 14-10-2018 IPR001610 PAC motif TSH58p_29450 cbe5d96f231adfe113204884afa7a4c0 692 SMART SM00086 210 250 12.0 T 14-10-2018 IPR001610 PAC motif TSH58p_29450 cbe5d96f231adfe113204884afa7a4c0 692 Gene3D G3DSA:3.20.20.450 432 691 2.3E-92 T 14-10-2018 IPR035919 EAL domain superfamily TSH58p_29450 cbe5d96f231adfe113204884afa7a4c0 692 Pfam PF00563 EAL domain 441 674 1.0E-68 T 14-10-2018 IPR001633 EAL domain TSH58p_29450 cbe5d96f231adfe113204884afa7a4c0 692 Pfam PF00989 PAS fold 138 247 2.2E-12 T 14-10-2018 IPR013767 PAS fold GO:0006355 TSH58p_29450 cbe5d96f231adfe113204884afa7a4c0 692 SUPERFAMILY SSF55785 145 256 4.32E-27 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_29450 cbe5d96f231adfe113204884afa7a4c0 692 SMART SM00267 250 423 1.0E-25 T 14-10-2018 IPR000160 GGDEF domain TSH58p_29450 cbe5d96f231adfe113204884afa7a4c0 692 SMART SM00091 134 200 2.6E-9 T 14-10-2018 IPR000014 PAS domain TSH58p_29450 cbe5d96f231adfe113204884afa7a4c0 692 SMART SM00091 10 75 0.013 T 14-10-2018 IPR000014 PAS domain TSH58p_29450 cbe5d96f231adfe113204884afa7a4c0 692 SUPERFAMILY SSF141868 441 686 2.88E-83 T 14-10-2018 IPR035919 EAL domain superfamily TSH58p_29450 cbe5d96f231adfe113204884afa7a4c0 692 Pfam PF00990 Diguanylate cyclase, GGDEF domain 261 418 6.7E-23 T 14-10-2018 IPR000160 GGDEF domain TSH58p_29450 cbe5d96f231adfe113204884afa7a4c0 692 Gene3D G3DSA:3.30.70.270 260 429 3.1E-35 T 14-10-2018 TSH58p_02295 1f9143d8146afc40253bb51f29ade2b1 232 SUPERFAMILY SSF52172 7 188 2.7E-44 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_02295 1f9143d8146afc40253bb51f29ade2b1 232 SMART SM00448 8 119 2.7E-43 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_02295 1f9143d8146afc40253bb51f29ade2b1 232 Pfam PF00072 Response regulator receiver domain 10 120 7.0E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_02295 1f9143d8146afc40253bb51f29ade2b1 232 SMART SM00862 154 228 3.9E-21 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_02295 1f9143d8146afc40253bb51f29ade2b1 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 228 2.9E-21 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_02295 1f9143d8146afc40253bb51f29ade2b1 232 Gene3D G3DSA:3.40.50.2300 6 133 3.2E-40 T 14-10-2018 TSH58p_02295 1f9143d8146afc40253bb51f29ade2b1 232 Gene3D G3DSA:1.10.10.10 134 232 7.5E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_09190 1c3cd6653adb9eed6cb2df885d2d58fb 398 SUPERFAMILY SSF141868 161 395 6.02E-44 T 14-10-2018 IPR035919 EAL domain superfamily TSH58p_09190 1c3cd6653adb9eed6cb2df885d2d58fb 398 Gene3D G3DSA:3.20.20.450 158 397 1.7E-47 T 14-10-2018 IPR035919 EAL domain superfamily TSH58p_09190 1c3cd6653adb9eed6cb2df885d2d58fb 398 SMART SM00052 155 396 3.6E-15 T 14-10-2018 IPR001633 EAL domain TSH58p_09190 1c3cd6653adb9eed6cb2df885d2d58fb 398 Pfam PF00563 EAL domain 161 391 1.1E-47 T 14-10-2018 IPR001633 EAL domain TSH58p_00765 172502b448b5262f14fd5eabafd9eb3b 550 SUPERFAMILY SSF90123 18 300 4.19E-22 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_00765 172502b448b5262f14fd5eabafd9eb3b 550 Pfam PF00005 ABC transporter 352 485 2.5E-20 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_00765 172502b448b5262f14fd5eabafd9eb3b 550 TIGRFAM TIGR01194 cyc_pep_trnsptr: cyclic peptide transporter 21 535 6.0E-94 T 14-10-2018 IPR005898 Cyclic peptide transporter GO:0005524|GO:0015833|GO:0016021|GO:1904680 TSH58p_00765 172502b448b5262f14fd5eabafd9eb3b 550 SUPERFAMILY SSF52540 327 546 4.82E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_00765 172502b448b5262f14fd5eabafd9eb3b 550 Gene3D G3DSA:1.20.1560.10 8 306 7.9E-15 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_00765 172502b448b5262f14fd5eabafd9eb3b 550 SMART SM00382 358 534 4.0E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_00765 172502b448b5262f14fd5eabafd9eb3b 550 Gene3D G3DSA:3.40.50.300 325 549 6.1E-38 T 14-10-2018 TSH58p_07895 c3090605cf82d7228a7c066fd4e173f8 714 Gene3D G3DSA:3.30.450.20 35 186 8.4E-59 T 14-10-2018 TSH58p_07895 c3090605cf82d7228a7c066fd4e173f8 714 Pfam PF17200 Single Cache domain 2 37 187 9.0E-45 T 14-10-2018 IPR033480 Single Cache domain 2 TSH58p_07895 c3090605cf82d7228a7c066fd4e173f8 714 SMART SM00304 211 264 1.4E-6 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_07895 c3090605cf82d7228a7c066fd4e173f8 714 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 580 702 6.2E-32 T 14-10-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 TSH58p_07895 c3090605cf82d7228a7c066fd4e173f8 714 SMART SM00283 300 554 1.8E-39 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_07895 c3090605cf82d7228a7c066fd4e173f8 714 Gene3D G3DSA:1.20.120.50 573 707 2.4E-33 T 14-10-2018 IPR035938 Hemerythrin-like superfamily TSH58p_07895 c3090605cf82d7228a7c066fd4e173f8 714 Pfam PF01814 Hemerythrin HHE cation binding domain 589 694 6.4E-11 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 TSH58p_07895 c3090605cf82d7228a7c066fd4e173f8 714 SUPERFAMILY SSF47188 577 703 4.19E-29 T 14-10-2018 IPR035938 Hemerythrin-like superfamily TSH58p_07895 c3090605cf82d7228a7c066fd4e173f8 714 Gene3D G3DSA:1.10.8.500 212 261 1.1E-14 T 14-10-2018 TSH58p_07895 c3090605cf82d7228a7c066fd4e173f8 714 SMART SM01049 34 128 3.7E-41 T 14-10-2018 IPR033480 Single Cache domain 2 TSH58p_07895 c3090605cf82d7228a7c066fd4e173f8 714 Pfam PF00672 HAMP domain 211 257 1.3E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_07895 c3090605cf82d7228a7c066fd4e173f8 714 SUPERFAMILY SSF58104 239 553 2.09E-59 T 14-10-2018 TSH58p_07895 c3090605cf82d7228a7c066fd4e173f8 714 ProSitePatterns PS00550 Hemerythrin family signature. 632 659 - T 14-10-2018 IPR016131 Haemerythrin, iron-binding site GO:0046872 TSH58p_07895 c3090605cf82d7228a7c066fd4e173f8 714 Gene3D G3DSA:1.10.287.950 269 554 6.6E-52 T 14-10-2018 TSH58p_07895 c3090605cf82d7228a7c066fd4e173f8 714 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 377 524 3.9E-30 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_07895 c3090605cf82d7228a7c066fd4e173f8 714 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 427 456 2.2E-8 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_07895 c3090605cf82d7228a7c066fd4e173f8 714 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 328 357 2.2E-8 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_22375 f4ffb2b52e5112defd3d51839dc36df9 454 Pfam PF01134 Glucose inhibited division protein A 9 380 2.6E-106 T 14-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 TSH58p_22375 f4ffb2b52e5112defd3d51839dc36df9 454 Gene3D G3DSA:3.50.50.60 7 185 2.6E-48 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_22375 f4ffb2b52e5112defd3d51839dc36df9 454 Gene3D G3DSA:3.50.50.60 303 453 7.5E-43 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_22375 f4ffb2b52e5112defd3d51839dc36df9 454 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 351 374 - T 14-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 TSH58p_22375 f4ffb2b52e5112defd3d51839dc36df9 454 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 8 447 9.8E-173 T 14-10-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 TSH58p_22375 f4ffb2b52e5112defd3d51839dc36df9 454 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 9 448 35.382 T 14-10-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 TSH58p_22375 f4ffb2b52e5112defd3d51839dc36df9 454 SUPERFAMILY SSF51905 9 376 1.45E-27 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_29125 1007294c1d9fc95d36b040a8e9d8bd7a 299 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 251 277 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_29125 1007294c1d9fc95d36b040a8e9d8bd7a 299 Gene3D G3DSA:1.20.140.160 151 282 1.8E-13 T 14-10-2018 TSH58p_29125 1007294c1d9fc95d36b040a8e9d8bd7a 299 SUPERFAMILY SSF88946 6 116 8.32E-39 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_29125 1007294c1d9fc95d36b040a8e9d8bd7a 299 Gene3D G3DSA:1.10.601.10 11 115 8.2E-33 T 14-10-2018 TSH58p_29125 1007294c1d9fc95d36b040a8e9d8bd7a 299 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 44 280 1.5E-27 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TSH58p_29125 1007294c1d9fc95d36b040a8e9d8bd7a 299 SUPERFAMILY SSF88659 190 282 7.66E-18 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSH58p_29125 1007294c1d9fc95d36b040a8e9d8bd7a 299 Pfam PF04542 Sigma-70 region 2 48 116 5.1E-17 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_29125 1007294c1d9fc95d36b040a8e9d8bd7a 299 PRINTS PR00046 Major sigma-70 factor signature 72 85 5.3E-21 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_29125 1007294c1d9fc95d36b040a8e9d8bd7a 299 PRINTS PR00046 Major sigma-70 factor signature 251 266 5.3E-21 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_29125 1007294c1d9fc95d36b040a8e9d8bd7a 299 PRINTS PR00046 Major sigma-70 factor signature 232 244 5.3E-21 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_29125 1007294c1d9fc95d36b040a8e9d8bd7a 299 PRINTS PR00046 Major sigma-70 factor signature 266 277 5.3E-21 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_29125 1007294c1d9fc95d36b040a8e9d8bd7a 299 PRINTS PR00046 Major sigma-70 factor signature 96 104 5.3E-21 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_29125 1007294c1d9fc95d36b040a8e9d8bd7a 299 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 11 282 8.8E-98 T 14-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_29125 1007294c1d9fc95d36b040a8e9d8bd7a 299 Pfam PF04545 Sigma-70, region 4 229 279 1.5E-16 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 TSH58p_29125 1007294c1d9fc95d36b040a8e9d8bd7a 299 Pfam PF00140 Sigma-70 factor, region 1.2 10 38 3.0E-5 T 14-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_09325 0184d236994d97c38e6b557acc63f0ba 593 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 9 593 1.5E-295 T 14-10-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_09325 0184d236994d97c38e6b557acc63f0ba 593 Gene3D G3DSA:3.90.700.10 248 351 2.9E-169 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_09325 0184d236994d97c38e6b557acc63f0ba 593 Pfam PF02910 Fumarate reductase flavoprotein C-term 460 593 9.1E-42 T 14-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_09325 0184d236994d97c38e6b557acc63f0ba 593 PIRSF PIRSF000171 1 583 9.4E-41 T 14-10-2018 TSH58p_09325 0184d236994d97c38e6b557acc63f0ba 593 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 46 55 - T 14-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_09325 0184d236994d97c38e6b557acc63f0ba 593 SUPERFAMILY SSF46977 451 593 1.83E-49 T 14-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_09325 0184d236994d97c38e6b557acc63f0ba 593 Gene3D G3DSA:3.50.50.60 12 417 2.9E-169 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_09325 0184d236994d97c38e6b557acc63f0ba 593 SUPERFAMILY SSF56425 238 356 2.84E-42 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_09325 0184d236994d97c38e6b557acc63f0ba 593 SUPERFAMILY SSF51905 4 428 5.52E-81 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_09325 0184d236994d97c38e6b557acc63f0ba 593 Pfam PF00890 FAD binding domain 12 406 4.6E-125 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_09325 0184d236994d97c38e6b557acc63f0ba 593 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 12 593 3.2E-246 T 14-10-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_09325 0184d236994d97c38e6b557acc63f0ba 593 Gene3D G3DSA:1.20.58.100 432 544 9.2E-37 T 14-10-2018 TSH58p_09325 0184d236994d97c38e6b557acc63f0ba 593 Gene3D G3DSA:4.10.80.40 545 593 2.1E-9 T 14-10-2018 TSH58p_31810 f5e80efab76d4eec6b24a6e7efd19d68 286 SMART SM00382 54 236 1.7E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_31810 f5e80efab76d4eec6b24a6e7efd19d68 286 SUPERFAMILY SSF52540 28 255 5.05E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_31810 f5e80efab76d4eec6b24a6e7efd19d68 286 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_31810 f5e80efab76d4eec6b24a6e7efd19d68 286 Gene3D G3DSA:3.40.50.300 26 257 1.3E-62 T 14-10-2018 TSH58p_31810 f5e80efab76d4eec6b24a6e7efd19d68 286 Pfam PF00005 ABC transporter 47 185 6.5E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_23680 21f15434b4f666c872f0d4025b0aa2da 84 Pfam PF13763 Domain of unknown function (DUF4167) 33 81 1.3E-12 T 14-10-2018 IPR025430 Domain of unknown function DUF4167 TSH58p_08595 9491c5e7df91a5286d324748cd73f45a 151 Pfam PF14437 MafB19-like deaminase 8 109 9.7E-22 T 14-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 TSH58p_08595 9491c5e7df91a5286d324748cd73f45a 151 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 55 92 - T 14-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 TSH58p_08595 9491c5e7df91a5286d324748cd73f45a 151 SUPERFAMILY SSF53927 7 150 1.75E-45 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TSH58p_08595 9491c5e7df91a5286d324748cd73f45a 151 Gene3D G3DSA:3.40.140.10 4 146 7.6E-49 T 14-10-2018 TSH58p_08595 9491c5e7df91a5286d324748cd73f45a 151 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 8 151 43.732 T 14-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 TSH58p_32215 758aa3f22a846462a7cc9563e7e02210 281 Gene3D G3DSA:3.40.1410.10 114 265 7.2E-27 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TSH58p_32215 758aa3f22a846462a7cc9563e7e02210 281 SUPERFAMILY SSF64288 104 276 1.07E-33 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TSH58p_32215 758aa3f22a846462a7cc9563e7e02210 281 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 90 106 2.6E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_32215 758aa3f22a846462a7cc9563e7e02210 281 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 76 90 2.6E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_32215 758aa3f22a846462a7cc9563e7e02210 281 SUPERFAMILY SSF46785 50 125 4.74E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_32215 758aa3f22a846462a7cc9563e7e02210 281 SMART SM00866 137 272 8.7E-16 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 TSH58p_32215 758aa3f22a846462a7cc9563e7e02210 281 Pfam PF07702 UTRA domain 138 271 1.7E-18 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 TSH58p_32215 758aa3f22a846462a7cc9563e7e02210 281 SMART SM00345 57 116 3.9E-21 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_32215 758aa3f22a846462a7cc9563e7e02210 281 Pfam PF00392 Bacterial regulatory proteins, gntR family 53 115 1.6E-21 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_32215 758aa3f22a846462a7cc9563e7e02210 281 Gene3D G3DSA:1.10.10.10 34 113 4.3E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_00440 fca4e95b2126d76107d9b7d304f76a11 409 SUPERFAMILY SSF56801 111 381 2.35E-30 T 14-10-2018 TSH58p_00440 fca4e95b2126d76107d9b7d304f76a11 409 Gene3D G3DSA:3.30.300.30 316 409 1.7E-13 T 14-10-2018 TSH58p_00440 fca4e95b2126d76107d9b7d304f76a11 409 Pfam PF00501 AMP-binding enzyme 139 276 1.4E-7 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_00440 fca4e95b2126d76107d9b7d304f76a11 409 Gene3D G3DSA:3.40.50.12780 2 315 1.6E-68 T 14-10-2018 TSH58p_00440 fca4e95b2126d76107d9b7d304f76a11 409 Pfam PF14535 AMP-binding enzyme C-terminal domain 324 400 6.7E-6 T 14-10-2018 IPR028154 AMP-dependent ligase, C-terminal TSH58p_12150 b2eac0d8c335295ce2659c83dc179156 94 Pfam PF02325 YGGT family 10 86 6.8E-23 T 14-10-2018 IPR003425 CCB3/YggT GO:0016020 TSH58p_07975 0cb543eba773973d7326a56c2767599c 945 Gene3D G3DSA:3.40.50.740 119 602 1.6E-137 T 14-10-2018 TSH58p_07975 0cb543eba773973d7326a56c2767599c 945 Gene3D G3DSA:2.20.25.90 53 106 2.4E-11 T 14-10-2018 TSH58p_07975 0cb543eba773973d7326a56c2767599c 945 SUPERFAMILY SSF53706 51 633 1.57E-201 T 14-10-2018 TSH58p_07975 0cb543eba773973d7326a56c2767599c 945 Gene3D G3DSA:3.40.228.10 187 386 1.6E-137 T 14-10-2018 TSH58p_07975 0cb543eba773973d7326a56c2767599c 945 Pfam PF01568 Molydopterin dinucleotide binding domain 812 938 1.1E-20 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TSH58p_07975 0cb543eba773973d7326a56c2767599c 945 SMART SM00926 53 107 1.6E-13 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_07975 0cb543eba773973d7326a56c2767599c 945 Gene3D G3DSA:2.40.40.20 761 945 7.6E-45 T 14-10-2018 TSH58p_07975 0cb543eba773973d7326a56c2767599c 945 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 54 106 1.2E-10 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_07975 0cb543eba773973d7326a56c2767599c 945 PIRSF PIRSF036643 14 567 1.4E-114 T 14-10-2018 TSH58p_07975 0cb543eba773973d7326a56c2767599c 945 PIRSF PIRSF036643 781 944 4.1E-16 T 14-10-2018 TSH58p_07975 0cb543eba773973d7326a56c2767599c 945 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 58 75 - T 14-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 TSH58p_07975 0cb543eba773973d7326a56c2767599c 945 SUPERFAMILY SSF50692 750 942 4.52E-37 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TSH58p_07975 0cb543eba773973d7326a56c2767599c 945 Pfam PF00384 Molybdopterin oxidoreductase 110 555 6.2E-57 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_07975 0cb543eba773973d7326a56c2767599c 945 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 10 37 8.1E-4 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal TSH58p_18885 1e9f6fa4b35ed6e49ff83327edbe8ef4 1025 Gene3D G3DSA:3.30.2090.10 178 268 8.9E-289 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_18885 1e9f6fa4b35ed6e49ff83327edbe8ef4 1025 Pfam PF00873 AcrB/AcrD/AcrF family 4 1004 8.9E-272 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_18885 1e9f6fa4b35ed6e49ff83327edbe8ef4 1025 Gene3D G3DSA:3.30.70.1440 648 843 8.9E-289 T 14-10-2018 TSH58p_18885 1e9f6fa4b35ed6e49ff83327edbe8ef4 1025 SUPERFAMILY SSF82693 137 323 1.1E-20 T 14-10-2018 TSH58p_18885 1e9f6fa4b35ed6e49ff83327edbe8ef4 1025 PRINTS PR00702 Acriflavin resistance protein family signature 540 557 1.1E-80 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_18885 1e9f6fa4b35ed6e49ff83327edbe8ef4 1025 PRINTS PR00702 Acriflavin resistance protein family signature 329 352 1.1E-80 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_18885 1e9f6fa4b35ed6e49ff83327edbe8ef4 1025 PRINTS PR00702 Acriflavin resistance protein family signature 437 460 1.1E-80 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_18885 1e9f6fa4b35ed6e49ff83327edbe8ef4 1025 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.1E-80 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_18885 1e9f6fa4b35ed6e49ff83327edbe8ef4 1025 PRINTS PR00702 Acriflavin resistance protein family signature 603 617 1.1E-80 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_18885 1e9f6fa4b35ed6e49ff83327edbe8ef4 1025 PRINTS PR00702 Acriflavin resistance protein family signature 384 408 1.1E-80 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_18885 1e9f6fa4b35ed6e49ff83327edbe8ef4 1025 PRINTS PR00702 Acriflavin resistance protein family signature 356 377 1.1E-80 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_18885 1e9f6fa4b35ed6e49ff83327edbe8ef4 1025 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.1E-80 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_18885 1e9f6fa4b35ed6e49ff83327edbe8ef4 1025 PRINTS PR00702 Acriflavin resistance protein family signature 462 485 1.1E-80 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_18885 1e9f6fa4b35ed6e49ff83327edbe8ef4 1025 SUPERFAMILY SSF82693 42 131 9.42E-25 T 14-10-2018 TSH58p_18885 1e9f6fa4b35ed6e49ff83327edbe8ef4 1025 Gene3D G3DSA:1.20.1640.10 10 500 8.9E-289 T 14-10-2018 TSH58p_18885 1e9f6fa4b35ed6e49ff83327edbe8ef4 1025 Gene3D G3DSA:3.30.2090.10 698 786 8.9E-289 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_18885 1e9f6fa4b35ed6e49ff83327edbe8ef4 1025 SUPERFAMILY SSF82714 183 265 9.81E-17 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_18885 1e9f6fa4b35ed6e49ff83327edbe8ef4 1025 SUPERFAMILY SSF82866 291 489 3.92E-51 T 14-10-2018 TSH58p_18885 1e9f6fa4b35ed6e49ff83327edbe8ef4 1025 SUPERFAMILY SSF82866 782 1006 4.19E-42 T 14-10-2018 TSH58p_18885 1e9f6fa4b35ed6e49ff83327edbe8ef4 1025 SUPERFAMILY SSF82714 699 784 2.75E-19 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_18885 1e9f6fa4b35ed6e49ff83327edbe8ef4 1025 Gene3D G3DSA:3.30.70.1320 134 325 8.9E-289 T 14-10-2018 TSH58p_18885 1e9f6fa4b35ed6e49ff83327edbe8ef4 1025 Gene3D G3DSA:3.30.70.1430 555 647 8.9E-289 T 14-10-2018 TSH58p_18885 1e9f6fa4b35ed6e49ff83327edbe8ef4 1025 Gene3D G3DSA:1.20.1640.10 501 1001 8.9E-289 T 14-10-2018 TSH58p_18885 1e9f6fa4b35ed6e49ff83327edbe8ef4 1025 SUPERFAMILY SSF82693 553 650 1.15E-19 T 14-10-2018 TSH58p_18885 1e9f6fa4b35ed6e49ff83327edbe8ef4 1025 Gene3D G3DSA:3.30.70.1430 40 794 8.9E-289 T 14-10-2018 TSH58p_06125 de2f887f5b7aa0b33bf7351226e73a85 363 Pfam PF02653 Branched-chain amino acid transport system / permease component 62 339 1.1E-42 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_23610 99f91591a1778712e49b3becfaba69e8 404 Gene3D G3DSA:3.40.50.2300 149 280 3.4E-103 T 14-10-2018 TSH58p_23610 99f91591a1778712e49b3becfaba69e8 404 Pfam PF13458 Periplasmic binding protein 29 366 3.9E-78 T 14-10-2018 IPR028081 Leucine-binding protein domain TSH58p_23610 99f91591a1778712e49b3becfaba69e8 404 SUPERFAMILY SSF53822 30 401 3.13E-86 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_23610 99f91591a1778712e49b3becfaba69e8 404 Gene3D G3DSA:3.40.50.2300 33 340 3.4E-103 T 14-10-2018 TSH58p_21070 056f69146744e6b426c5977203c835b2 196 SUPERFAMILY SSF88659 101 163 2.18E-13 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSH58p_21070 056f69146744e6b426c5977203c835b2 196 Pfam PF04542 Sigma-70 region 2 9 71 4.0E-13 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_21070 056f69146744e6b426c5977203c835b2 196 Pfam PF08281 Sigma-70, region 4 110 158 2.9E-12 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_21070 056f69146744e6b426c5977203c835b2 196 Gene3D G3DSA:1.10.1740.10 2 76 5.6E-11 T 14-10-2018 TSH58p_21070 056f69146744e6b426c5977203c835b2 196 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 158 2.1E-23 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TSH58p_21070 056f69146744e6b426c5977203c835b2 196 Gene3D G3DSA:1.10.10.10 85 169 1.5E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_21070 056f69146744e6b426c5977203c835b2 196 SUPERFAMILY SSF88946 6 81 1.77E-15 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_13325 8d89c66779d53c655bb1a5e3ed68e757 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 258 5.9E-47 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TSH58p_13325 8d89c66779d53c655bb1a5e3ed68e757 259 Gene3D G3DSA:3.90.226.10 1 203 3.1E-63 T 14-10-2018 TSH58p_13325 8d89c66779d53c655bb1a5e3ed68e757 259 Gene3D G3DSA:1.10.12.10 204 259 1.3E-28 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal TSH58p_13325 8d89c66779d53c655bb1a5e3ed68e757 259 SUPERFAMILY SSF52096 3 259 1.25E-70 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_32400 7ecbfac9b8b0aa3be68af8cb9f0dc938 478 SUPERFAMILY SSF55103 192 471 1.44E-48 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 TSH58p_32400 7ecbfac9b8b0aa3be68af8cb9f0dc938 478 Gene3D G3DSA:3.30.70.2190 219 342 1.1E-34 T 14-10-2018 TSH58p_32400 7ecbfac9b8b0aa3be68af8cb9f0dc938 478 SUPERFAMILY SSF56176 5 219 3.0E-70 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TSH58p_32400 7ecbfac9b8b0aa3be68af8cb9f0dc938 478 Gene3D G3DSA:3.30.70.2740 343 431 1.7E-21 T 14-10-2018 TSH58p_32400 7ecbfac9b8b0aa3be68af8cb9f0dc938 478 Pfam PF01565 FAD binding domain 43 179 1.4E-35 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TSH58p_32400 7ecbfac9b8b0aa3be68af8cb9f0dc938 478 Gene3D G3DSA:3.30.465.10 97 218 4.7E-45 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TSH58p_32400 7ecbfac9b8b0aa3be68af8cb9f0dc938 478 Gene3D G3DSA:1.10.45.10 432 472 3.4E-13 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 TSH58p_32400 7ecbfac9b8b0aa3be68af8cb9f0dc938 478 Pfam PF02913 FAD linked oxidases, C-terminal domain 219 471 1.6E-49 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 TSH58p_32400 7ecbfac9b8b0aa3be68af8cb9f0dc938 478 Gene3D G3DSA:3.30.43.10 2 95 3.9E-23 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 TSH58p_21330 e590f2b9a140301d4ef91449c59a7dfe 191 Pfam PF01195 Peptidyl-tRNA hydrolase 3 183 2.2E-56 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 TSH58p_21330 e590f2b9a140301d4ef91449c59a7dfe 191 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 14 27 - T 14-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 TSH58p_21330 e590f2b9a140301d4ef91449c59a7dfe 191 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 1 183 3.8E-58 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 TSH58p_21330 e590f2b9a140301d4ef91449c59a7dfe 191 SUPERFAMILY SSF53178 1 183 8.11E-71 T 14-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 TSH58p_21330 e590f2b9a140301d4ef91449c59a7dfe 191 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 177 35.725 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 TSH58p_21330 e590f2b9a140301d4ef91449c59a7dfe 191 Gene3D G3DSA:3.40.50.1470 1 188 8.2E-70 T 14-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 TSH58p_21330 e590f2b9a140301d4ef91449c59a7dfe 191 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 107 117 - T 14-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 TSH58p_27755 d16b699c426ad469e4c811ab07348926 334 SMART SM00829 4 332 0.0017 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TSH58p_27755 d16b699c426ad469e4c811ab07348926 334 Pfam PF00107 Zinc-binding dehydrogenase 168 294 5.6E-31 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TSH58p_27755 d16b699c426ad469e4c811ab07348926 334 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 54 68 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 TSH58p_27755 d16b699c426ad469e4c811ab07348926 334 Gene3D G3DSA:3.40.50.720 145 278 2.4E-88 T 14-10-2018 TSH58p_27755 d16b699c426ad469e4c811ab07348926 334 SUPERFAMILY SSF51735 135 294 8.12E-41 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_27755 d16b699c426ad469e4c811ab07348926 334 Gene3D G3DSA:3.90.180.10 12 317 2.4E-88 T 14-10-2018 TSH58p_27755 d16b699c426ad469e4c811ab07348926 334 SUPERFAMILY SSF50129 9 164 3.96E-38 T 14-10-2018 IPR011032 GroES-like superfamily TSH58p_27755 d16b699c426ad469e4c811ab07348926 334 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 20 125 5.6E-27 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TSH58p_07660 966d5745f582e1d1ed0fcd697cc4758c 495 SUPERFAMILY SSF55785 146 253 9.34E-24 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_07660 966d5745f582e1d1ed0fcd697cc4758c 495 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 21 132 1.4E-17 T 14-10-2018 IPR000014 PAS domain TSH58p_07660 966d5745f582e1d1ed0fcd697cc4758c 495 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 144 253 4.2E-12 T 14-10-2018 IPR000014 PAS domain TSH58p_07660 966d5745f582e1d1ed0fcd697cc4758c 495 Pfam PF13426 PAS domain 25 128 1.7E-13 T 14-10-2018 IPR000014 PAS domain TSH58p_07660 966d5745f582e1d1ed0fcd697cc4758c 495 Gene3D G3DSA:3.30.450.20 130 274 3.7E-23 T 14-10-2018 TSH58p_07660 966d5745f582e1d1ed0fcd697cc4758c 495 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 318 481 1.0E-28 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_07660 966d5745f582e1d1ed0fcd697cc4758c 495 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 381 410 2.0E-8 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_07660 966d5745f582e1d1ed0fcd697cc4758c 495 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 282 311 2.0E-8 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_07660 966d5745f582e1d1ed0fcd697cc4758c 495 Gene3D G3DSA:1.10.287.950 279 495 2.0E-38 T 14-10-2018 TSH58p_07660 966d5745f582e1d1ed0fcd697cc4758c 495 SUPERFAMILY SSF58104 268 494 3.53E-45 T 14-10-2018 TSH58p_07660 966d5745f582e1d1ed0fcd697cc4758c 495 SMART SM00086 87 129 4.2E-4 T 14-10-2018 IPR001610 PAC motif TSH58p_07660 966d5745f582e1d1ed0fcd697cc4758c 495 SMART SM00086 209 251 6.7E-4 T 14-10-2018 IPR001610 PAC motif TSH58p_07660 966d5745f582e1d1ed0fcd697cc4758c 495 Gene3D G3DSA:3.30.450.20 22 129 2.8E-20 T 14-10-2018 TSH58p_07660 966d5745f582e1d1ed0fcd697cc4758c 495 SMART SM00091 14 82 6.6 T 14-10-2018 IPR000014 PAS domain TSH58p_07660 966d5745f582e1d1ed0fcd697cc4758c 495 SMART SM00091 128 204 7.1 T 14-10-2018 IPR000014 PAS domain TSH58p_07660 966d5745f582e1d1ed0fcd697cc4758c 495 Pfam PF08447 PAS fold 159 244 4.4E-13 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 TSH58p_07660 966d5745f582e1d1ed0fcd697cc4758c 495 SMART SM00283 268 494 7.5E-23 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_07660 966d5745f582e1d1ed0fcd697cc4758c 495 SUPERFAMILY SSF55785 25 130 1.29E-23 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_28810 4407c22ff95bc404bbff1942cda8181f 338 Pfam PF13531 Bacterial extracellular solute-binding protein 36 287 1.8E-43 T 14-10-2018 TSH58p_28810 4407c22ff95bc404bbff1942cda8181f 338 ProSitePatterns PS00757 Prokaryotic sulfate-binding proteins signature 2. 152 160 - T 14-10-2018 IPR034408 Sulphate/thiosulphate-binding site GO:1901681 TSH58p_28810 4407c22ff95bc404bbff1942cda8181f 338 SUPERFAMILY SSF53850 30 334 7.25E-86 T 14-10-2018 TSH58p_28810 4407c22ff95bc404bbff1942cda8181f 338 Gene3D G3DSA:3.40.190.10 34 302 1.2E-135 T 14-10-2018 TSH58p_28810 4407c22ff95bc404bbff1942cda8181f 338 Gene3D G3DSA:3.40.190.10 121 332 1.2E-135 T 14-10-2018 TSH58p_28810 4407c22ff95bc404bbff1942cda8181f 338 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 25 333 3.8E-144 T 14-10-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 TSH58p_24835 760eed4a8177b509ca1293c3a40cfcae 747 Pfam PF02706 Chain length determinant protein 4 94 6.7E-12 T 14-10-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 TSH58p_24835 760eed4a8177b509ca1293c3a40cfcae 747 Gene3D G3DSA:3.40.50.300 469 737 3.4E-45 T 14-10-2018 TSH58p_24835 760eed4a8177b509ca1293c3a40cfcae 747 SUPERFAMILY SSF52540 546 700 2.66E-23 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_26780 50434da952f38a23b602eec1edac82c3 244 SMART SM00382 28 215 3.3E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_26780 50434da952f38a23b602eec1edac82c3 244 Gene3D G3DSA:3.40.50.300 1 242 2.6E-74 T 14-10-2018 TSH58p_26780 50434da952f38a23b602eec1edac82c3 244 SUPERFAMILY SSF52540 3 237 6.34E-76 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_26780 50434da952f38a23b602eec1edac82c3 244 PIRSF PIRSF039085 1 243 3.1E-106 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 TSH58p_26780 50434da952f38a23b602eec1edac82c3 244 Pfam PF00005 ABC transporter 19 167 5.0E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_26780 50434da952f38a23b602eec1edac82c3 244 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_10670 794415d912ac4c2ef51400c4128e120b 396 Gene3D G3DSA:3.40.50.2300 166 377 2.8E-41 T 14-10-2018 TSH58p_10670 794415d912ac4c2ef51400c4128e120b 396 Gene3D G3DSA:3.40.50.2300 57 369 2.8E-41 T 14-10-2018 TSH58p_10670 794415d912ac4c2ef51400c4128e120b 396 Pfam PF13458 Periplasmic binding protein 55 380 2.5E-42 T 14-10-2018 IPR028081 Leucine-binding protein domain TSH58p_10670 794415d912ac4c2ef51400c4128e120b 396 SUPERFAMILY SSF53822 57 383 1.33E-62 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_02925 a651d078c1482c73ba445c1e862ca9eb 210 Gene3D G3DSA:3.40.50.150 6 207 1.7E-31 T 14-10-2018 TSH58p_02925 a651d078c1482c73ba445c1e862ca9eb 210 Pfam PF13649 Methyltransferase domain 49 142 6.0E-19 T 14-10-2018 TSH58p_02925 a651d078c1482c73ba445c1e862ca9eb 210 SUPERFAMILY SSF53335 14 200 1.22E-33 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_19945 4a4e85ce944194d57dd9b7d7847f37da 455 Pfam PF00072 Response regulator receiver domain 3 112 8.7E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_19945 4a4e85ce944194d57dd9b7d7847f37da 455 Pfam PF00158 Sigma-54 interaction domain 142 308 2.3E-65 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 TSH58p_19945 4a4e85ce944194d57dd9b7d7847f37da 455 SMART SM00448 1 112 2.4E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_19945 4a4e85ce944194d57dd9b7d7847f37da 455 Gene3D G3DSA:3.40.50.300 135 312 1.4E-60 T 14-10-2018 TSH58p_19945 4a4e85ce944194d57dd9b7d7847f37da 455 Pfam PF02954 Bacterial regulatory protein, Fis family 406 443 1.5E-13 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_19945 4a4e85ce944194d57dd9b7d7847f37da 455 Gene3D G3DSA:1.10.8.60 313 377 9.2E-20 T 14-10-2018 TSH58p_19945 4a4e85ce944194d57dd9b7d7847f37da 455 SMART SM00382 162 305 5.3E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_19945 4a4e85ce944194d57dd9b7d7847f37da 455 SUPERFAMILY SSF52540 142 372 8.11E-71 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_19945 4a4e85ce944194d57dd9b7d7847f37da 455 Gene3D G3DSA:1.10.10.60 397 449 1.8E-13 T 14-10-2018 TSH58p_19945 4a4e85ce944194d57dd9b7d7847f37da 455 SUPERFAMILY SSF46689 400 447 2.06E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_19945 4a4e85ce944194d57dd9b7d7847f37da 455 SUPERFAMILY SSF52172 1 185 1.85E-40 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_19945 4a4e85ce944194d57dd9b7d7847f37da 455 Gene3D G3DSA:3.40.50.2300 1 134 9.9E-35 T 14-10-2018 TSH58p_19945 4a4e85ce944194d57dd9b7d7847f37da 455 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 355 364 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site TSH58p_19945 4a4e85ce944194d57dd9b7d7847f37da 455 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 228 243 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 TSH58p_19945 4a4e85ce944194d57dd9b7d7847f37da 455 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 166 179 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 TSH58p_19945 4a4e85ce944194d57dd9b7d7847f37da 455 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 411 428 1.1E-7 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_19945 4a4e85ce944194d57dd9b7d7847f37da 455 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 428 448 1.1E-7 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_07770 9218190bb7fecf824ca0b3f877fa2a04 991 Gene3D G3DSA:3.30.565.10 425 590 2.7E-53 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_07770 9218190bb7fecf824ca0b3f877fa2a04 991 SUPERFAMILY SSF47226 874 987 1.83E-20 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_07770 9218190bb7fecf824ca0b3f877fa2a04 991 Pfam PF11849 Domain of unknown function (DUF3369) 152 323 3.9E-40 T 14-10-2018 IPR021800 Domain of unknown function DUF3369 TSH58p_07770 9218190bb7fecf824ca0b3f877fa2a04 991 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 473 586 5.0E-31 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_07770 9218190bb7fecf824ca0b3f877fa2a04 991 SMART SM00073 892 989 5.7E-8 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TSH58p_07770 9218190bb7fecf824ca0b3f877fa2a04 991 SUPERFAMILY SSF52172 736 862 3.84E-36 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_07770 9218190bb7fecf824ca0b3f877fa2a04 991 SUPERFAMILY SSF47384 348 427 3.34E-21 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_07770 9218190bb7fecf824ca0b3f877fa2a04 991 Gene3D G3DSA:3.40.50.2300 733 857 4.6E-37 T 14-10-2018 TSH58p_07770 9218190bb7fecf824ca0b3f877fa2a04 991 Pfam PF01627 Hpt domain 901 972 1.8E-9 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TSH58p_07770 9218190bb7fecf824ca0b3f877fa2a04 991 Gene3D G3DSA:1.10.287.130 325 424 5.1E-29 T 14-10-2018 TSH58p_07770 9218190bb7fecf824ca0b3f877fa2a04 991 Pfam PF00072 Response regulator receiver domain 739 852 2.6E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_07770 9218190bb7fecf824ca0b3f877fa2a04 991 Pfam PF00072 Response regulator receiver domain 32 142 1.2E-7 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_07770 9218190bb7fecf824ca0b3f877fa2a04 991 SMART SM00387 473 589 2.4E-38 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_07770 9218190bb7fecf824ca0b3f877fa2a04 991 SMART SM00448 30 152 0.011 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_07770 9218190bb7fecf824ca0b3f877fa2a04 991 SMART SM00448 737 853 2.4E-34 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_07770 9218190bb7fecf824ca0b3f877fa2a04 991 Pfam PF00512 His Kinase A (phospho-acceptor) domain 362 426 4.9E-19 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_07770 9218190bb7fecf824ca0b3f877fa2a04 991 PRINTS PR00344 Bacterial sensor protein C-terminal signature 549 567 4.9E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_07770 9218190bb7fecf824ca0b3f877fa2a04 991 PRINTS PR00344 Bacterial sensor protein C-terminal signature 532 542 4.9E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_07770 9218190bb7fecf824ca0b3f877fa2a04 991 PRINTS PR00344 Bacterial sensor protein C-terminal signature 514 528 4.9E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_07770 9218190bb7fecf824ca0b3f877fa2a04 991 PRINTS PR00344 Bacterial sensor protein C-terminal signature 573 586 4.9E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_07770 9218190bb7fecf824ca0b3f877fa2a04 991 Gene3D G3DSA:3.40.50.2300 31 169 3.1E-14 T 14-10-2018 TSH58p_07770 9218190bb7fecf824ca0b3f877fa2a04 991 SMART SM00388 361 426 2.2E-24 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_07770 9218190bb7fecf824ca0b3f877fa2a04 991 SUPERFAMILY SSF52172 26 164 9.53E-14 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_07770 9218190bb7fecf824ca0b3f877fa2a04 991 Gene3D G3DSA:1.20.120.160 879 988 1.3E-15 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_07770 9218190bb7fecf824ca0b3f877fa2a04 991 SUPERFAMILY SSF55874 415 585 6.94E-48 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_01125 af3759ef459ef7571247d6d50e5235a4 192 SUPERFAMILY SSF50475 2 180 3.57E-51 T 14-10-2018 TSH58p_01125 af3759ef459ef7571247d6d50e5235a4 192 Gene3D G3DSA:1.20.58.290 120 190 2.7E-23 T 14-10-2018 TSH58p_01125 af3759ef459ef7571247d6d50e5235a4 192 Gene3D G3DSA:2.30.110.10 1 119 7.1E-33 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TSH58p_01125 af3759ef459ef7571247d6d50e5235a4 192 Pfam PF04289 Protein of unknown function (DUF447) 6 178 2.7E-46 T 14-10-2018 IPR007386 Protein of unknown function DUF447 TSH58p_00210 a163087d97908f6efcb8d9088047c5c2 486 SMART SM00345 25 84 8.8E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_00210 a163087d97908f6efcb8d9088047c5c2 486 Gene3D G3DSA:3.40.640.10 117 472 1.5E-115 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_00210 a163087d97908f6efcb8d9088047c5c2 486 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 58 2.3E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_00210 a163087d97908f6efcb8d9088047c5c2 486 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 58 74 2.3E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_00210 a163087d97908f6efcb8d9088047c5c2 486 Gene3D G3DSA:1.10.10.10 18 96 2.7E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_00210 a163087d97908f6efcb8d9088047c5c2 486 SUPERFAMILY SSF46785 14 86 1.18E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_00210 a163087d97908f6efcb8d9088047c5c2 486 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 84 7.9E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_00210 a163087d97908f6efcb8d9088047c5c2 486 SUPERFAMILY SSF53383 117 478 3.26E-91 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_00210 a163087d97908f6efcb8d9088047c5c2 486 Pfam PF00155 Aminotransferase class I and II 152 471 3.5E-25 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSH58p_17820 801a998ab9b5724d8e6cd78eed9a9a88 1077 Pfam PF13692 Glycosyl transferases group 1 905 1019 2.3E-8 T 14-10-2018 TSH58p_17820 801a998ab9b5724d8e6cd78eed9a9a88 1077 Pfam PF13524 Glycosyl transferases group 1 591 665 3.5E-8 T 14-10-2018 TSH58p_17820 801a998ab9b5724d8e6cd78eed9a9a88 1077 Gene3D G3DSA:3.90.550.10 1 285 5.4E-39 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_17820 801a998ab9b5724d8e6cd78eed9a9a88 1077 Gene3D G3DSA:3.40.50.2000 880 1034 1.3E-16 T 14-10-2018 TSH58p_17820 801a998ab9b5724d8e6cd78eed9a9a88 1077 SUPERFAMILY SSF53448 4 257 2.66E-38 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_17820 801a998ab9b5724d8e6cd78eed9a9a88 1077 Gene3D G3DSA:3.40.50.2000 504 656 1.5E-14 T 14-10-2018 TSH58p_17820 801a998ab9b5724d8e6cd78eed9a9a88 1077 SUPERFAMILY SSF53756 358 671 5.02E-21 T 14-10-2018 TSH58p_17820 801a998ab9b5724d8e6cd78eed9a9a88 1077 Pfam PF00535 Glycosyl transferase family 2 6 138 3.4E-23 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_17820 801a998ab9b5724d8e6cd78eed9a9a88 1077 SUPERFAMILY SSF53756 735 1049 4.29E-20 T 14-10-2018 TSH58p_05235 f26497ef8b43f847a4e2c297072759b0 599 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 41 592 1.7E-161 T 14-10-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 TSH58p_05235 f26497ef8b43f847a4e2c297072759b0 599 SUPERFAMILY SSF64182 69 480 1.02E-112 T 14-10-2018 IPR038763 DHH phosphoesterase superfamily TSH58p_05235 f26497ef8b43f847a4e2c297072759b0 599 Gene3D G3DSA:3.90.1640.30 70 342 2.2E-86 T 14-10-2018 TSH58p_05235 f26497ef8b43f847a4e2c297072759b0 599 Pfam PF02272 DHHA1 domain 338 464 7.6E-19 T 14-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TSH58p_05235 f26497ef8b43f847a4e2c297072759b0 599 Gene3D G3DSA:3.10.310.30 343 472 9.4E-27 T 14-10-2018 TSH58p_05235 f26497ef8b43f847a4e2c297072759b0 599 Pfam PF01368 DHH family 96 197 2.4E-8 T 14-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 TSH58p_30330 3a44de59a21d5f48f8ca3855e5c8db1b 328 Gene3D G3DSA:3.10.520.20 28 328 9.2E-76 T 14-10-2018 TSH58p_30330 3a44de59a21d5f48f8ca3855e5c8db1b 328 Pfam PF02424 ApbE family 62 310 6.6E-61 T 14-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 TSH58p_30330 3a44de59a21d5f48f8ca3855e5c8db1b 328 SUPERFAMILY SSF143631 32 322 7.32E-75 T 14-10-2018 IPR003374 ApbE-like superfamily TSH58p_30330 3a44de59a21d5f48f8ca3855e5c8db1b 328 PIRSF PIRSF006268 24 327 6.3E-60 T 14-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 TSH58p_02650 9854257af405e437051a6dc97326ec80 442 SUPERFAMILY SSF103473 16 420 3.92E-52 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_02650 9854257af405e437051a6dc97326ec80 442 TIGRFAM TIGR04259 oxa_formateAnti: oxalate/formate antiporter 21 425 8.2E-189 T 14-10-2018 IPR026355 Oxalate/formate antiporter GO:0016021|GO:0019531|GO:0019532 TSH58p_02650 9854257af405e437051a6dc97326ec80 442 Gene3D G3DSA:1.20.1250.20 14 428 1.1E-49 T 14-10-2018 TSH58p_02650 9854257af405e437051a6dc97326ec80 442 Pfam PF07690 Major Facilitator Superfamily 29 282 6.1E-28 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_02640 db9bf21d39d56ca80330ad20c1374ce4 169 Pfam PF13187 4Fe-4S dicluster domain 111 156 6.9E-8 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_02640 db9bf21d39d56ca80330ad20c1374ce4 169 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 142 153 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_02640 db9bf21d39d56ca80330ad20c1374ce4 169 Pfam PF12838 4Fe-4S dicluster domain 39 83 4.5E-8 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_02640 db9bf21d39d56ca80330ad20c1374ce4 169 TIGRFAM TIGR00402 napF: ferredoxin-type protein NapF 10 158 9.4E-38 T 14-10-2018 IPR004496 Ferredoxin-type protein NapF GO:0051539 TSH58p_02640 db9bf21d39d56ca80330ad20c1374ce4 169 Hamap MF_02201 Ferredoxin-type protein NapF [napF]. 28 163 24.086 T 14-10-2018 IPR004496 Ferredoxin-type protein NapF GO:0051539 TSH58p_02640 db9bf21d39d56ca80330ad20c1374ce4 169 Gene3D G3DSA:3.30.70.20 33 86 4.7E-11 T 14-10-2018 TSH58p_02640 db9bf21d39d56ca80330ad20c1374ce4 169 SUPERFAMILY SSF54862 35 161 5.72E-20 T 14-10-2018 TSH58p_02640 db9bf21d39d56ca80330ad20c1374ce4 169 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 39 50 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_02640 db9bf21d39d56ca80330ad20c1374ce4 169 Gene3D G3DSA:3.30.70.20 100 160 1.1E-10 T 14-10-2018 TSH58p_27700 bd59a9ac46f1760fb3dafb3a645dedab 372 Gene3D G3DSA:3.40.50.720 175 313 3.2E-155 T 14-10-2018 TSH58p_27700 bd59a9ac46f1760fb3dafb3a645dedab 372 SMART SM00829 13 368 0.0048 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TSH58p_27700 bd59a9ac46f1760fb3dafb3a645dedab 372 SUPERFAMILY SSF51735 161 335 9.17E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_27700 bd59a9ac46f1760fb3dafb3a645dedab 372 SUPERFAMILY SSF50129 2 185 1.08E-74 T 14-10-2018 IPR011032 GroES-like superfamily TSH58p_27700 bd59a9ac46f1760fb3dafb3a645dedab 372 Gene3D G3DSA:3.90.180.10 7 365 3.2E-155 T 14-10-2018 TSH58p_27700 bd59a9ac46f1760fb3dafb3a645dedab 372 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 3 370 1.1E-221 T 14-10-2018 IPR014183 Alcohol dehydrogenase class III GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|MetaCyc: PWY-7798|Reactome: R-HSA-71384 TSH58p_27700 bd59a9ac46f1760fb3dafb3a645dedab 372 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 154 2.3E-26 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TSH58p_27700 bd59a9ac46f1760fb3dafb3a645dedab 372 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 TSH58p_27700 bd59a9ac46f1760fb3dafb3a645dedab 372 Pfam PF00107 Zinc-binding dehydrogenase 198 326 5.9E-25 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TSH58p_27700 bd59a9ac46f1760fb3dafb3a645dedab 372 SUPERFAMILY SSF50129 320 370 3.06E-12 T 14-10-2018 IPR011032 GroES-like superfamily TSH58p_00235 74329fc5962d41f2dca6aed2fa3cd613 453 SUPERFAMILY SSF53383 25 450 2.34E-116 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_00235 74329fc5962d41f2dca6aed2fa3cd613 453 Pfam PF00202 Aminotransferase class-III 40 449 2.3E-92 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSH58p_00235 74329fc5962d41f2dca6aed2fa3cd613 453 Gene3D G3DSA:3.40.640.10 75 355 9.1E-152 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_00235 74329fc5962d41f2dca6aed2fa3cd613 453 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 261 298 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSH58p_00235 74329fc5962d41f2dca6aed2fa3cd613 453 Gene3D G3DSA:3.90.1150.10 38 444 9.1E-152 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 SMART SM00388 469 535 1.2E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 Gene3D G3DSA:3.30.450.20 213 329 2.1E-11 T 14-10-2018 TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 Gene3D G3DSA:3.30.450.20 90 212 3.9E-11 T 14-10-2018 TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 Pfam PF00072 Response regulator receiver domain 723 833 3.9E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 Pfam PF00512 His Kinase A (phospho-acceptor) domain 470 533 2.4E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 211 335 2.5E-7 T 14-10-2018 IPR000014 PAS domain TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 338 460 1.0E-12 T 14-10-2018 IPR000014 PAS domain TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 SUPERFAMILY SSF55785 329 452 6.81E-17 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 Gene3D G3DSA:3.30.450.20 330 460 6.1E-17 T 14-10-2018 TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 Gene3D G3DSA:3.30.565.10 538 706 6.1E-46 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 Gene3D G3DSA:3.40.50.2300 715 841 2.1E-28 T 14-10-2018 TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 Gene3D G3DSA:1.10.287.130 461 534 1.5E-21 T 14-10-2018 TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 PRINTS PR00344 Bacterial sensor protein C-terminal signature 659 677 1.4E-19 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 PRINTS PR00344 Bacterial sensor protein C-terminal signature 628 642 1.4E-19 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 PRINTS PR00344 Bacterial sensor protein C-terminal signature 683 696 1.4E-19 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 PRINTS PR00344 Bacterial sensor protein C-terminal signature 646 656 1.4E-19 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 SMART SM00387 576 699 3.2E-32 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 SMART SM00448 721 833 9.2E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 SUPERFAMILY SSF55785 96 204 1.08E-8 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 Pfam PF13426 PAS domain 224 326 0.01 T 14-10-2018 IPR000014 PAS domain TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 SUPERFAMILY SSF52172 721 838 5.27E-28 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 SMART SM00091 214 282 6.3E-4 T 14-10-2018 IPR000014 PAS domain TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 SMART SM00091 90 158 0.0017 T 14-10-2018 IPR000014 PAS domain TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 SMART SM00091 340 406 9.1E-10 T 14-10-2018 IPR000014 PAS domain TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 SUPERFAMILY SSF55874 525 699 6.68E-41 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 SUPERFAMILY SSF47384 462 533 1.61E-11 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 SUPERFAMILY SSF55785 199 326 1.5E-14 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 Pfam PF00989 PAS fold 95 177 1.9E-5 T 14-10-2018 IPR013767 PAS fold GO:0006355 TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 Pfam PF08448 PAS fold 346 455 4.2E-11 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_15515 03ad9da6f4e0a69c226e1f2e890140c9 841 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 577 697 1.1E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_13080 53aa49bbb7e827c7173ad1cae29f12d0 169 Pfam PF16242 Pyridoxamine 5'-phosphate oxidase like 9 157 5.6E-50 T 14-10-2018 IPR038725 General stress protein, FMN-binding split barrel domain TSH58p_13080 53aa49bbb7e827c7173ad1cae29f12d0 169 Gene3D G3DSA:2.30.110.10 7 168 1.3E-55 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TSH58p_13080 53aa49bbb7e827c7173ad1cae29f12d0 169 SUPERFAMILY SSF50475 11 141 1.87E-35 T 14-10-2018 TSH58p_25635 3afa7148fc58843ef5c1a357a6853ffd 614 Gene3D G3DSA:3.40.1440.10 4 102 7.6E-28 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 TSH58p_25635 3afa7148fc58843ef5c1a357a6853ffd 614 Pfam PF14520 Helix-hairpin-helix domain 563 609 1.4E-6 T 14-10-2018 TSH58p_25635 3afa7148fc58843ef5c1a357a6853ffd 614 SUPERFAMILY SSF46600 195 246 1.44E-7 T 14-10-2018 IPR036876 UVR domain superfamily TSH58p_25635 3afa7148fc58843ef5c1a357a6853ffd 614 SMART SM00278 592 611 8.4 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TSH58p_25635 3afa7148fc58843ef5c1a357a6853ffd 614 SMART SM00278 560 579 87.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TSH58p_25635 3afa7148fc58843ef5c1a357a6853ffd 614 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 386 546 7.2E-47 T 14-10-2018 IPR001162 UvrC family homology region TSH58p_25635 3afa7148fc58843ef5c1a357a6853ffd 614 SMART SM00465 17 98 3.0E-17 T 14-10-2018 IPR000305 GIY-YIG endonuclease TSH58p_25635 3afa7148fc58843ef5c1a357a6853ffd 614 SUPERFAMILY SSF47781 525 613 2.0E-21 T 14-10-2018 IPR010994 RuvA domain 2-like TSH58p_25635 3afa7148fc58843ef5c1a357a6853ffd 614 SUPERFAMILY SSF82771 17 99 5.36E-19 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 TSH58p_25635 3afa7148fc58843ef5c1a357a6853ffd 614 Pfam PF02151 UvrB/uvrC motif 219 239 9.4E-5 T 14-10-2018 IPR001943 UVR domain GO:0005515 TSH58p_25635 3afa7148fc58843ef5c1a357a6853ffd 614 Gene3D G3DSA:1.10.150.20 554 612 1.3E-16 T 14-10-2018 TSH58p_25635 3afa7148fc58843ef5c1a357a6853ffd 614 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 611 25.566 T 14-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 TSH58p_25635 3afa7148fc58843ef5c1a357a6853ffd 614 Pfam PF01541 GIY-YIG catalytic domain 19 90 6.5E-7 T 14-10-2018 IPR000305 GIY-YIG endonuclease TSH58p_25635 3afa7148fc58843ef5c1a357a6853ffd 614 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 10 592 5.0E-139 T 14-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 TSH58p_25635 3afa7148fc58843ef5c1a357a6853ffd 614 Gene3D G3DSA:3.30.420.340 379 553 2.3E-45 T 14-10-2018 IPR038476 UvrC homology region 2 superfamily TSH58p_28210 09b6d28b3de846d75bf135ad7e5e5be0 68 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 4.5E-22 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_28210 09b6d28b3de846d75bf135ad7e5e5be0 68 PRINTS PR00050 Cold shock protein signature 25 34 5.5E-11 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_28210 09b6d28b3de846d75bf135ad7e5e5be0 68 PRINTS PR00050 Cold shock protein signature 39 57 5.5E-11 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_28210 09b6d28b3de846d75bf135ad7e5e5be0 68 PRINTS PR00050 Cold shock protein signature 4 19 5.5E-11 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_28210 09b6d28b3de846d75bf135ad7e5e5be0 68 SMART SM00357 3 68 2.3E-19 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 TSH58p_28210 09b6d28b3de846d75bf135ad7e5e5be0 68 Gene3D G3DSA:2.40.50.140 1 68 3.7E-23 T 14-10-2018 TSH58p_28210 09b6d28b3de846d75bf135ad7e5e5be0 68 SUPERFAMILY SSF50249 1 61 2.29E-20 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_28210 09b6d28b3de846d75bf135ad7e5e5be0 68 PIRSF PIRSF002599 1 68 1.4E-20 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 TSH58p_28210 09b6d28b3de846d75bf135ad7e5e5be0 68 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 14-10-2018 IPR019844 Cold-shock conserved site TSH58p_08515 e1257229a23c7369fdf47d398dd121b7 274 SUPERFAMILY SSF64518 1 274 4.84E-71 T 14-10-2018 TSH58p_08515 e1257229a23c7369fdf47d398dd121b7 274 Gene3D G3DSA:1.10.8.410 226 274 2.3E-18 T 14-10-2018 TSH58p_08515 e1257229a23c7369fdf47d398dd121b7 274 Pfam PF00700 Bacterial flagellin C-terminal helical region 189 273 2.4E-20 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 TSH58p_08515 e1257229a23c7369fdf47d398dd121b7 274 Pfam PF00669 Bacterial flagellin N-terminal helical region 4 140 4.2E-32 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 TSH58p_08515 e1257229a23c7369fdf47d398dd121b7 274 PRINTS PR00207 Flagellin signature 75 94 4.5E-16 T 14-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 TSH58p_08515 e1257229a23c7369fdf47d398dd121b7 274 PRINTS PR00207 Flagellin signature 110 133 4.5E-16 T 14-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 TSH58p_08515 e1257229a23c7369fdf47d398dd121b7 274 PRINTS PR00207 Flagellin signature 36 53 4.5E-16 T 14-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 TSH58p_08515 e1257229a23c7369fdf47d398dd121b7 274 Gene3D G3DSA:1.20.1330.10 53 225 4.1E-45 T 14-10-2018 TSH58p_03345 336ffd1796aa128afb4a86a22dcb6936 890 SMART SM00382 199 344 2.9E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_03345 336ffd1796aa128afb4a86a22dcb6936 890 SMART SM00382 594 764 1.7E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_03345 336ffd1796aa128afb4a86a22dcb6936 890 SUPERFAMILY SSF52540 543 843 4.25E-76 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_03345 336ffd1796aa128afb4a86a22dcb6936 890 Gene3D G3DSA:3.40.50.300 547 761 5.5E-82 T 14-10-2018 TSH58p_03345 336ffd1796aa128afb4a86a22dcb6936 890 Gene3D G3DSA:1.10.1780.10 3 148 7.9E-25 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 TSH58p_03345 336ffd1796aa128afb4a86a22dcb6936 890 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 204 316 6.1E-13 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSH58p_03345 336ffd1796aa128afb4a86a22dcb6936 890 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 705 719 2.8E-38 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 TSH58p_03345 336ffd1796aa128afb4a86a22dcb6936 890 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 643 661 2.8E-38 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 TSH58p_03345 336ffd1796aa128afb4a86a22dcb6936 890 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 598 616 2.8E-38 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 TSH58p_03345 336ffd1796aa128afb4a86a22dcb6936 890 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 672 690 2.8E-38 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 TSH58p_03345 336ffd1796aa128afb4a86a22dcb6936 890 Gene3D G3DSA:3.40.50.300 345 541 1.4E-63 T 14-10-2018 TSH58p_03345 336ffd1796aa128afb4a86a22dcb6936 890 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 1.5E-9 T 14-10-2018 IPR004176 Clp, N-terminal TSH58p_03345 336ffd1796aa128afb4a86a22dcb6936 890 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 144 3.2E-6 T 14-10-2018 IPR004176 Clp, N-terminal TSH58p_03345 336ffd1796aa128afb4a86a22dcb6936 890 Gene3D G3DSA:1.10.8.60 763 854 2.1E-25 T 14-10-2018 TSH58p_03345 336ffd1796aa128afb4a86a22dcb6936 890 SUPERFAMILY SSF81923 6 154 7.32E-28 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 TSH58p_03345 336ffd1796aa128afb4a86a22dcb6936 890 Gene3D G3DSA:3.40.50.300 149 343 1.1E-74 T 14-10-2018 TSH58p_03345 336ffd1796aa128afb4a86a22dcb6936 890 SUPERFAMILY SSF52540 161 524 2.11E-94 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_03345 336ffd1796aa128afb4a86a22dcb6936 890 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 763 842 1.6E-23 T 14-10-2018 IPR019489 Clp ATPase, C-terminal TSH58p_03345 336ffd1796aa128afb4a86a22dcb6936 890 Pfam PF07724 AAA domain (Cdc48 subfamily) 593 756 7.5E-51 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSH58p_03345 336ffd1796aa128afb4a86a22dcb6936 890 SMART SM01086 763 852 1.9E-33 T 14-10-2018 IPR019489 Clp ATPase, C-terminal TSH58p_03345 336ffd1796aa128afb4a86a22dcb6936 890 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 295 307 - T 14-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 TSH58p_03345 336ffd1796aa128afb4a86a22dcb6936 890 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 852 0.0 T 14-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 TSH58p_03345 336ffd1796aa128afb4a86a22dcb6936 890 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 628 646 - T 14-10-2018 IPR028299 ClpA/B, conserved site 2 TSH58p_04625 67c8e8fbe7082c82737fc7fbe2614c06 329 Pfam PF03741 Integral membrane protein TerC family 82 288 4.1E-57 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 TSH58p_04625 67c8e8fbe7082c82737fc7fbe2614c06 329 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 16 320 1.8E-123 T 14-10-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 TSH58p_20135 210f792a0a54de74e9da65493f7c4896 248 Hamap MF_00415 Flagellar L-ring protein [flgH]. 1 246 24.37 T 14-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 TSH58p_20135 210f792a0a54de74e9da65493f7c4896 248 PRINTS PR01008 Flagellar L-ring protein signature 162 177 8.8E-27 T 14-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 TSH58p_20135 210f792a0a54de74e9da65493f7c4896 248 PRINTS PR01008 Flagellar L-ring protein signature 225 239 8.8E-27 T 14-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 TSH58p_20135 210f792a0a54de74e9da65493f7c4896 248 PRINTS PR01008 Flagellar L-ring protein signature 209 223 8.8E-27 T 14-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 TSH58p_20135 210f792a0a54de74e9da65493f7c4896 248 PRINTS PR01008 Flagellar L-ring protein signature 188 204 8.8E-27 T 14-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 TSH58p_20135 210f792a0a54de74e9da65493f7c4896 248 PRINTS PR01008 Flagellar L-ring protein signature 83 95 8.8E-27 T 14-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 TSH58p_20135 210f792a0a54de74e9da65493f7c4896 248 Pfam PF02107 Flagellar L-ring protein 64 247 9.7E-56 T 14-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 TSH58p_03190 6ed34fe2ea0cb2cb5a5a0e3a5d5bcb28 304 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 289 6.0E-42 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_16985 b6e175c969db41b88cb0d67429458572 387 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 42 117 7.4E-5 T 14-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 TSH58p_16985 b6e175c969db41b88cb0d67429458572 387 Gene3D G3DSA:3.20.20.70 119 358 3.9E-25 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_16985 b6e175c969db41b88cb0d67429458572 387 SUPERFAMILY SSF51690 126 381 1.38E-29 T 14-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 TSH58p_16985 b6e175c969db41b88cb0d67429458572 387 SUPERFAMILY SSF54675 24 117 2.49E-8 T 14-10-2018 TSH58p_23065 4a2270b5116ae287a43f7f88a614f46e 397 Gene3D G3DSA:3.40.50.10540 3 391 4.9E-121 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily TSH58p_23065 4a2270b5116ae287a43f7f88a614f46e 397 Pfam PF02515 CoA-transferase family III 4 374 1.2E-110 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 TSH58p_23065 4a2270b5116ae287a43f7f88a614f46e 397 SUPERFAMILY SSF89796 1 397 8.63E-124 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily TSH58p_23065 4a2270b5116ae287a43f7f88a614f46e 397 Gene3D G3DSA:3.30.1540.10 230 323 4.9E-121 T 14-10-2018 TSH58p_20575 6f4f1d56d3b41d0acba5012cabcd48da 334 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 49 266 1.7E-36 T 14-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 TSH58p_20575 6f4f1d56d3b41d0acba5012cabcd48da 334 Gene3D G3DSA:3.40.50.2300 135 323 1.2E-66 T 14-10-2018 TSH58p_20575 6f4f1d56d3b41d0acba5012cabcd48da 334 Gene3D G3DSA:3.40.50.2300 35 288 1.2E-66 T 14-10-2018 TSH58p_27500 2ad0a63b4150095de23f3e9fec49bef5 920 SMART SM00387 342 485 5.8E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_27500 2ad0a63b4150095de23f3e9fec49bef5 920 Pfam PF01627 Hpt domain 3 95 1.1E-16 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TSH58p_27500 2ad0a63b4150095de23f3e9fec49bef5 920 Gene3D G3DSA:3.30.565.10 298 484 1.0E-56 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_27500 2ad0a63b4150095de23f3e9fec49bef5 920 SUPERFAMILY SSF50341 651 768 1.19E-12 T 14-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 TSH58p_27500 2ad0a63b4150095de23f3e9fec49bef5 920 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 345 484 7.1E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_27500 2ad0a63b4150095de23f3e9fec49bef5 920 Gene3D G3DSA:3.40.50.2300 783 919 2.5E-30 T 14-10-2018 TSH58p_27500 2ad0a63b4150095de23f3e9fec49bef5 920 Pfam PF00072 Response regulator receiver domain 797 908 2.3E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_27500 2ad0a63b4150095de23f3e9fec49bef5 920 Gene3D G3DSA:1.10.287.560 237 297 1.6E-17 T 14-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 TSH58p_27500 2ad0a63b4150095de23f3e9fec49bef5 920 SUPERFAMILY SSF55874 301 483 2.1E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_27500 2ad0a63b4150095de23f3e9fec49bef5 920 SMART SM01231 237 297 7.2E-19 T 14-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 TSH58p_27500 2ad0a63b4150095de23f3e9fec49bef5 920 Gene3D G3DSA:1.20.120.160 1 137 1.1E-33 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_27500 2ad0a63b4150095de23f3e9fec49bef5 920 SUPERFAMILY SSF52172 796 914 1.71E-31 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_27500 2ad0a63b4150095de23f3e9fec49bef5 920 Gene3D G3DSA:2.30.30.40 485 617 1.6E-38 T 14-10-2018 TSH58p_27500 2ad0a63b4150095de23f3e9fec49bef5 920 Gene3D G3DSA:2.40.50.180 508 577 1.6E-38 T 14-10-2018 TSH58p_27500 2ad0a63b4150095de23f3e9fec49bef5 920 Pfam PF01584 CheW-like domain 490 623 2.0E-23 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TSH58p_27500 2ad0a63b4150095de23f3e9fec49bef5 920 Pfam PF01584 CheW-like domain 652 738 2.0E-5 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TSH58p_27500 2ad0a63b4150095de23f3e9fec49bef5 920 SMART SM00260 647 772 0.0036 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TSH58p_27500 2ad0a63b4150095de23f3e9fec49bef5 920 SMART SM00260 477 622 7.9E-37 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TSH58p_27500 2ad0a63b4150095de23f3e9fec49bef5 920 SUPERFAMILY SSF50341 484 621 3.66E-30 T 14-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 TSH58p_27500 2ad0a63b4150095de23f3e9fec49bef5 920 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 238 297 6.4E-14 T 14-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 TSH58p_27500 2ad0a63b4150095de23f3e9fec49bef5 920 SUPERFAMILY SSF47226 1 123 9.29E-31 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_27500 2ad0a63b4150095de23f3e9fec49bef5 920 SMART SM00073 1 98 2.1E-31 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TSH58p_27500 2ad0a63b4150095de23f3e9fec49bef5 920 SMART SM00448 795 909 4.6E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_27500 2ad0a63b4150095de23f3e9fec49bef5 920 SUPERFAMILY SSF47384 238 298 4.32E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_27500 2ad0a63b4150095de23f3e9fec49bef5 920 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 463 9.0E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_27500 2ad0a63b4150095de23f3e9fec49bef5 920 PRINTS PR00344 Bacterial sensor protein C-terminal signature 387 401 9.0E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_27500 2ad0a63b4150095de23f3e9fec49bef5 920 PRINTS PR00344 Bacterial sensor protein C-terminal signature 469 482 9.0E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_02110 ec1de60a7d6cab833cfda6919afb8a24 361 Pfam PF00571 CBS domain 298 344 1.6E-7 T 14-10-2018 IPR000644 CBS domain TSH58p_02110 ec1de60a7d6cab833cfda6919afb8a24 361 Pfam PF00571 CBS domain 233 288 7.8E-10 T 14-10-2018 IPR000644 CBS domain TSH58p_02110 ec1de60a7d6cab833cfda6919afb8a24 361 Pfam PF02163 Peptidase family M50 47 118 4.9E-10 T 14-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TSH58p_02110 ec1de60a7d6cab833cfda6919afb8a24 361 SMART SM00116 303 351 7.5 T 14-10-2018 IPR000644 CBS domain TSH58p_02110 ec1de60a7d6cab833cfda6919afb8a24 361 SMART SM00116 240 288 1.1E-5 T 14-10-2018 IPR000644 CBS domain TSH58p_02110 ec1de60a7d6cab833cfda6919afb8a24 361 Gene3D G3DSA:3.10.580.10 212 287 9.2E-11 T 14-10-2018 TSH58p_02110 ec1de60a7d6cab833cfda6919afb8a24 361 SUPERFAMILY SSF54631 230 346 1.77E-24 T 14-10-2018 TSH58p_02110 ec1de60a7d6cab833cfda6919afb8a24 361 PIRSF PIRSF006404 1 359 2.1E-115 T 14-10-2018 IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS TSH58p_02110 ec1de60a7d6cab833cfda6919afb8a24 361 Gene3D G3DSA:3.10.580.10 288 350 3.3E-9 T 14-10-2018 TSH58p_02110 ec1de60a7d6cab833cfda6919afb8a24 361 Pfam PF02163 Peptidase family M50 133 191 8.7E-8 T 14-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 Gene3D G3DSA:1.25.40.10 112 306 2.0E-54 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 Gene3D G3DSA:1.25.40.10 318 429 8.8E-40 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 SUPERFAMILY SSF81901 22 293 7.85E-57 T 14-10-2018 TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 SUPERFAMILY SSF81901 331 544 1.1E-51 T 14-10-2018 TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 Gene3D G3DSA:1.25.40.10 15 111 4.6E-21 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 Gene3D G3DSA:1.25.40.10 452 546 2.0E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 Pfam PF08238 Sel1 repeat 250 285 4.4E-7 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 Pfam PF08238 Sel1 repeat 286 321 0.039 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 Pfam PF08238 Sel1 repeat 330 357 2.3E-5 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 Pfam PF08238 Sel1 repeat 49 84 8.1E-9 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 Pfam PF08238 Sel1 repeat 178 212 7.4E-5 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 Pfam PF08238 Sel1 repeat 144 177 5.2E-8 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 Pfam PF08238 Sel1 repeat 431 465 2.1E-5 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 Pfam PF08238 Sel1 repeat 395 429 1.1E-8 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 Pfam PF08238 Sel1 repeat 468 499 2.6E-5 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 Pfam PF08238 Sel1 repeat 502 536 1.5E-4 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 Pfam PF08238 Sel1 repeat 358 393 2.3E-10 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 Pfam PF08238 Sel1 repeat 86 140 0.031 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 Pfam PF08238 Sel1 repeat 215 248 7.3E-5 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 SMART SM00671 430 465 3.5E-7 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 SMART SM00671 85 141 8.1 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 SMART SM00671 49 84 3.1E-9 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 SMART SM00671 358 393 3.1E-11 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 SMART SM00671 214 249 7.9E-7 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 SMART SM00671 178 213 0.0043 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 SMART SM00671 502 536 0.08 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 SMART SM00671 286 321 0.0015 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 SMART SM00671 322 357 9.7E-5 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 SMART SM00671 250 285 4.0E-8 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 SMART SM00671 394 429 5.2E-7 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 SMART SM00671 466 501 8.2E-4 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_18390 4e3fea0952134a474902a743ed1b2763 569 SMART SM00671 142 177 1.6E-9 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_04750 5efdf79f2e102febedd35eb2c045aa6a 1327 TIGRFAM TIGR02353 NRPS_term_dom: non-ribosomal peptide synthetase terminal domain of unknown function 615 1309 2.8E-182 T 14-10-2018 IPR012728 Non-ribosomal peptide synthetase, C-terminal TSH58p_04750 5efdf79f2e102febedd35eb2c045aa6a 1327 SUPERFAMILY SSF56801 9 522 1.01E-149 T 14-10-2018 TSH58p_04750 5efdf79f2e102febedd35eb2c045aa6a 1327 Gene3D G3DSA:2.160.10.10 1210 1326 1.4E-12 T 14-10-2018 TSH58p_04750 5efdf79f2e102febedd35eb2c045aa6a 1327 Gene3D G3DSA:3.40.50.12780 5 396 3.0E-126 T 14-10-2018 TSH58p_04750 5efdf79f2e102febedd35eb2c045aa6a 1327 SUPERFAMILY SSF51161 959 1078 1.8E-15 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily TSH58p_04750 5efdf79f2e102febedd35eb2c045aa6a 1327 SUPERFAMILY SSF51161 1154 1313 1.16E-17 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily TSH58p_04750 5efdf79f2e102febedd35eb2c045aa6a 1327 SUPERFAMILY SSF47336 508 581 4.06E-9 T 14-10-2018 IPR036736 ACP-like superfamily TSH58p_04750 5efdf79f2e102febedd35eb2c045aa6a 1327 Gene3D G3DSA:3.30.300.30 398 498 7.3E-32 T 14-10-2018 TSH58p_04750 5efdf79f2e102febedd35eb2c045aa6a 1327 Pfam PF00550 Phosphopantetheine attachment site 526 581 1.2E-5 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain TSH58p_04750 5efdf79f2e102febedd35eb2c045aa6a 1327 SUPERFAMILY SSF51161 712 834 1.66E-13 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily TSH58p_04750 5efdf79f2e102febedd35eb2c045aa6a 1327 Gene3D G3DSA:1.10.1200.10 500 587 3.2E-14 T 14-10-2018 IPR036736 ACP-like superfamily TSH58p_04750 5efdf79f2e102febedd35eb2c045aa6a 1327 Pfam PF13193 AMP-binding enzyme C-terminal domain 412 486 1.9E-11 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSH58p_04750 5efdf79f2e102febedd35eb2c045aa6a 1327 Gene3D G3DSA:2.160.10.10 931 1079 1.8E-7 T 14-10-2018 TSH58p_04750 5efdf79f2e102febedd35eb2c045aa6a 1327 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 35 428 1.6E-126 T 14-10-2018 IPR010071 Amino acid adenylation domain TSH58p_04750 5efdf79f2e102febedd35eb2c045aa6a 1327 Gene3D G3DSA:2.160.10.10 717 837 6.9E-11 T 14-10-2018 TSH58p_04750 5efdf79f2e102febedd35eb2c045aa6a 1327 Pfam PF00501 AMP-binding enzyme 14 404 1.0E-96 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_29600 ea7f9bd9142ef3e62d264322ce4deb2e 662 SMART SM00331 429 647 5.4E-29 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSH58p_29600 ea7f9bd9142ef3e62d264322ce4deb2e 662 SUPERFAMILY SSF81606 443 595 8.11E-5 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSH58p_29600 ea7f9bd9142ef3e62d264322ce4deb2e 662 Gene3D G3DSA:3.60.40.10 396 649 7.8E-59 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSH58p_29600 ea7f9bd9142ef3e62d264322ce4deb2e 662 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 456 647 7.9E-36 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSH58p_29600 ea7f9bd9142ef3e62d264322ce4deb2e 662 Pfam PF00672 HAMP domain 325 374 1.4E-6 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_29600 ea7f9bd9142ef3e62d264322ce4deb2e 662 SMART SM00304 325 380 0.0021 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_27735 18ea0f4354b17495565c4d11e99f33d9 495 SMART SM00858 11 80 3.3E-12 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 TSH58p_27735 18ea0f4354b17495565c4d11e99f33d9 495 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 107 494 1.9E-148 T 14-10-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 TSH58p_27735 18ea0f4354b17495565c4d11e99f33d9 495 Pfam PF08666 SAF domain 11 79 1.7E-12 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 TSH58p_27735 18ea0f4354b17495565c4d11e99f33d9 495 Gene3D G3DSA:3.90.1210.30 3 83 5.8E-24 T 14-10-2018 TSH58p_20255 cbc020f54ad9ed3c0434593a7890bd32 298 Gene3D G3DSA:1.10.1740.10 6 77 4.3E-10 T 14-10-2018 TSH58p_20255 cbc020f54ad9ed3c0434593a7890bd32 298 Pfam PF04542 Sigma-70 region 2 11 75 2.7E-14 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_20255 cbc020f54ad9ed3c0434593a7890bd32 298 SUPERFAMILY SSF54427 170 287 1.54E-10 T 14-10-2018 IPR032710 NTF2-like domain superfamily TSH58p_20255 cbc020f54ad9ed3c0434593a7890bd32 298 Gene3D G3DSA:1.10.10.10 103 158 1.9E-8 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_20255 cbc020f54ad9ed3c0434593a7890bd32 298 SUPERFAMILY SSF88659 100 156 4.49E-9 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSH58p_20255 cbc020f54ad9ed3c0434593a7890bd32 298 Pfam PF08281 Sigma-70, region 4 107 154 6.4E-10 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_20255 cbc020f54ad9ed3c0434593a7890bd32 298 SUPERFAMILY SSF88946 10 88 5.1E-13 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_08505 73b65decf0466d4789d9140d4587719e 573 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 512 571 7.0E-9 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain TSH58p_08505 73b65decf0466d4789d9140d4587719e 573 SUPERFAMILY SSF64518 141 573 4.45E-6 T 14-10-2018 TSH58p_08505 73b65decf0466d4789d9140d4587719e 573 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 9 327 1.7E-65 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 TSH58p_05860 c3357ee0124b0c7e4db161cc72f04e62 700 Pfam PF00361 Proton-conducting membrane transporter 188 478 6.8E-92 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05860 c3357ee0124b0c7e4db161cc72f04e62 700 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 481 503 9.3E-12 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 TSH58p_05860 c3357ee0124b0c7e4db161cc72f04e62 700 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 139 159 9.3E-12 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 TSH58p_05860 c3357ee0124b0c7e4db161cc72f04e62 700 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 327 349 9.3E-12 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 TSH58p_05860 c3357ee0124b0c7e4db161cc72f04e62 700 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 119 176 5.2E-24 T 14-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05860 c3357ee0124b0c7e4db161cc72f04e62 700 Pfam PF06455 NADH dehydrogenase subunit 5 C-terminus 573 693 6.0E-8 T 14-10-2018 IPR010934 NADH dehydrogenase subunit 5, C-terminal GO:0008137|GO:0042773|GO:0055114 KEGG: 00190+1.6.5.3|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-5083|MetaCyc: PWY-6692|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05860 c3357ee0124b0c7e4db161cc72f04e62 700 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 212 233 6.9E-64 T 14-10-2018 TSH58p_05860 c3357ee0124b0c7e4db161cc72f04e62 700 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 137 162 6.9E-64 T 14-10-2018 TSH58p_05860 c3357ee0124b0c7e4db161cc72f04e62 700 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 287 308 6.9E-64 T 14-10-2018 TSH58p_05860 c3357ee0124b0c7e4db161cc72f04e62 700 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 309 335 6.9E-64 T 14-10-2018 TSH58p_05860 c3357ee0124b0c7e4db161cc72f04e62 700 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 377 389 6.9E-64 T 14-10-2018 TSH58p_05860 c3357ee0124b0c7e4db161cc72f04e62 700 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 165 185 6.9E-64 T 14-10-2018 TSH58p_05860 c3357ee0124b0c7e4db161cc72f04e62 700 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 482 501 6.9E-64 T 14-10-2018 TSH58p_05860 c3357ee0124b0c7e4db161cc72f04e62 700 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 81 696 4.5E-259 T 14-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_11290 3ddefdfd5455b7ce1402a396abd2714e 416 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 232 411 3.6E-20 T 14-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 TSH58p_11290 3ddefdfd5455b7ce1402a396abd2714e 416 Gene3D G3DSA:3.30.70.1230 220 415 5.7E-47 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_11290 3ddefdfd5455b7ce1402a396abd2714e 416 SMART SM00044 194 397 2.7E-6 T 14-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 TSH58p_11290 3ddefdfd5455b7ce1402a396abd2714e 416 SUPERFAMILY SSF55073 224 412 1.15E-46 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_04350 dec9948ea74304d9ba4786e3664d2e84 235 Gene3D G3DSA:2.40.30.130 1 89 2.4E-19 T 14-10-2018 TSH58p_04350 dec9948ea74304d9ba4786e3664d2e84 235 SUPERFAMILY SSF50447 2 89 4.24E-16 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSH58p_04350 dec9948ea74304d9ba4786e3664d2e84 235 Gene3D G3DSA:3.30.980.10 90 235 3.7E-31 T 14-10-2018 TSH58p_04350 dec9948ea74304d9ba4786e3664d2e84 235 SMART SM00863 187 230 3.4E-12 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TSH58p_04350 dec9948ea74304d9ba4786e3664d2e84 235 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 187 229 1.3E-10 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TSH58p_04350 dec9948ea74304d9ba4786e3664d2e84 235 SUPERFAMILY SSF55186 90 231 1.83E-29 T 14-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 TSH58p_04350 dec9948ea74304d9ba4786e3664d2e84 235 Pfam PF01411 tRNA synthetases class II (A) 14 93 1.1E-10 T 14-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 TSH58p_01415 1a899476bad958ff0fc27155fa293698 412 SUPERFAMILY SSF47005 116 160 4.84E-10 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TSH58p_01415 1a899476bad958ff0fc27155fa293698 412 Gene3D G3DSA:2.40.50.100 2 103 1.8E-22 T 14-10-2018 TSH58p_01415 1a899476bad958ff0fc27155fa293698 412 Gene3D G3DSA:3.30.559.10 164 408 5.8E-64 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TSH58p_01415 1a899476bad958ff0fc27155fa293698 412 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 181 409 3.6E-60 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 TSH58p_01415 1a899476bad958ff0fc27155fa293698 412 SUPERFAMILY SSF51230 2 98 2.49E-24 T 14-10-2018 IPR011053 Single hybrid motif TSH58p_01415 1a899476bad958ff0fc27155fa293698 412 SUPERFAMILY SSF52777 169 409 2.4E-58 T 14-10-2018 TSH58p_01415 1a899476bad958ff0fc27155fa293698 412 Gene3D G3DSA:4.10.320.10 122 161 1.9E-14 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TSH58p_01415 1a899476bad958ff0fc27155fa293698 412 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 29 58 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 TSH58p_01415 1a899476bad958ff0fc27155fa293698 412 Pfam PF00364 Biotin-requiring enzyme 6 77 1.5E-16 T 14-10-2018 IPR000089 Biotin/lipoyl attachment TSH58p_01415 1a899476bad958ff0fc27155fa293698 412 Pfam PF02817 e3 binding domain 122 157 3.2E-11 T 14-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 TSH58p_00450 52085450653069fb2bfe956a0aea08b0 390 Gene3D G3DSA:1.10.540.10 3 128 8.5E-51 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TSH58p_00450 52085450653069fb2bfe956a0aea08b0 390 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 225 2.8E-26 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TSH58p_00450 52085450653069fb2bfe956a0aea08b0 390 Gene3D G3DSA:2.40.110.10 129 242 1.5E-45 T 14-10-2018 TSH58p_00450 52085450653069fb2bfe956a0aea08b0 390 SUPERFAMILY SSF47203 236 388 2.9E-47 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TSH58p_00450 52085450653069fb2bfe956a0aea08b0 390 PIRSF PIRSF016578 13 390 1.7E-16 T 14-10-2018 TSH58p_00450 52085450653069fb2bfe956a0aea08b0 390 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 344 363 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TSH58p_00450 52085450653069fb2bfe956a0aea08b0 390 Gene3D G3DSA:1.20.140.10 243 390 3.5E-47 T 14-10-2018 TSH58p_00450 52085450653069fb2bfe956a0aea08b0 390 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 15 126 3.4E-40 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TSH58p_00450 52085450653069fb2bfe956a0aea08b0 390 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 237 385 1.3E-43 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TSH58p_00450 52085450653069fb2bfe956a0aea08b0 390 SUPERFAMILY SSF56645 6 250 2.09E-89 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TSH58p_00450 52085450653069fb2bfe956a0aea08b0 390 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 132 144 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TSH58p_25655 4711923760fb61903e1a939268f5340e 120 ProSitePatterns PS00768 Transthyretin signature 1. 10 25 - T 14-10-2018 IPR023418 Transthyretin, thyroxine binding site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 TSH58p_25655 4711923760fb61903e1a939268f5340e 120 Pfam PF00576 HIUase/Transthyretin family 7 119 1.1E-37 T 14-10-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase domain Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 TSH58p_25655 4711923760fb61903e1a939268f5340e 120 ProSitePatterns PS00769 Transthyretin signature 2. 103 115 - T 14-10-2018 IPR023419 Transthyretin, conserved site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 TSH58p_25655 4711923760fb61903e1a939268f5340e 120 SUPERFAMILY SSF49472 4 120 3.27E-44 T 14-10-2018 IPR036817 Transthyretin/hydroxyisourate hydrolase domain superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 TSH58p_25655 4711923760fb61903e1a939268f5340e 120 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 6 120 8.7E-42 T 14-10-2018 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 TSH58p_25655 4711923760fb61903e1a939268f5340e 120 Gene3D G3DSA:2.60.40.180 1 120 2.7E-43 T 14-10-2018 IPR036817 Transthyretin/hydroxyisourate hydrolase domain superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 TSH58p_25655 4711923760fb61903e1a939268f5340e 120 PRINTS PR00189 Transthyretin signature 98 120 9.5E-9 T 14-10-2018 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 TSH58p_25655 4711923760fb61903e1a939268f5340e 120 PRINTS PR00189 Transthyretin signature 6 26 9.5E-9 T 14-10-2018 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 TSH58p_30355 d1b132da489d045754938057c5f34f8e 647 Gene3D G3DSA:2.60.40.420 525 643 6.7E-34 T 14-10-2018 IPR008972 Cupredoxin TSH58p_30355 d1b132da489d045754938057c5f34f8e 647 SUPERFAMILY SSF50974 64 513 2.49E-140 T 14-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 TSH58p_30355 d1b132da489d045754938057c5f34f8e 647 Hamap MF_00716 Nitrous-oxide reductase [nosZ]. 2 644 57.202 T 14-10-2018 IPR023644 Nitrous-oxide reductase GO:0005507|GO:0005509|GO:0050304|GO:0055114 KEGG: 00910+1.7.2.4|MetaCyc: PWY-6748|MetaCyc: PWY-7084 TSH58p_30355 d1b132da489d045754938057c5f34f8e 647 TIGRFAM TIGR04244 nitrous_NosZ_RR: nitrous-oxide reductase, TAT-dependent 16 643 0.0 T 14-10-2018 IPR023644 Nitrous-oxide reductase GO:0005507|GO:0005509|GO:0050304|GO:0055114 KEGG: 00910+1.7.2.4|MetaCyc: PWY-6748|MetaCyc: PWY-7084 TSH58p_30355 d1b132da489d045754938057c5f34f8e 647 SUPERFAMILY SSF49503 518 644 6.63E-37 T 14-10-2018 IPR008972 Cupredoxin TSH58p_30355 d1b132da489d045754938057c5f34f8e 647 Gene3D G3DSA:2.130.10.10 63 524 1.2E-198 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TSH58p_21270 12f3aac2a87d52563e149cba0dd6770c 897 Gene3D G3DSA:3.30.1490.20 19 251 1.0E-106 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSH58p_21270 12f3aac2a87d52563e149cba0dd6770c 897 Gene3D G3DSA:3.50.30.10 403 527 7.0E-79 T 14-10-2018 TSH58p_21270 12f3aac2a87d52563e149cba0dd6770c 897 Gene3D G3DSA:1.20.80.30 119 206 1.0E-106 T 14-10-2018 TSH58p_21270 12f3aac2a87d52563e149cba0dd6770c 897 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 7 889 0.0 T 14-10-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 TSH58p_21270 12f3aac2a87d52563e149cba0dd6770c 897 PIRSF PIRSF000853 6 896 0.0 T 14-10-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 TSH58p_21270 12f3aac2a87d52563e149cba0dd6770c 897 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 535 887 6.4E-90 T 14-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 TSH58p_21270 12f3aac2a87d52563e149cba0dd6770c 897 Gene3D G3DSA:3.30.470.20 252 361 3.5E-39 T 14-10-2018 TSH58p_21270 12f3aac2a87d52563e149cba0dd6770c 897 Gene3D G3DSA:1.10.189.10 365 547 7.0E-79 T 14-10-2018 TSH58p_21270 12f3aac2a87d52563e149cba0dd6770c 897 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 70 376 1.0E-53 T 14-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 TSH58p_21270 12f3aac2a87d52563e149cba0dd6770c 897 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 26 63 5.7E-11 T 14-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 TSH58p_21270 12f3aac2a87d52563e149cba0dd6770c 897 Gene3D G3DSA:3.20.20.60 550 891 4.0E-150 T 14-10-2018 TSH58p_21270 12f3aac2a87d52563e149cba0dd6770c 897 SUPERFAMILY SSF51621 529 889 1.74E-130 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSH58p_21270 12f3aac2a87d52563e149cba0dd6770c 897 SUPERFAMILY SSF56059 7 398 1.0E-148 T 14-10-2018 TSH58p_21270 12f3aac2a87d52563e149cba0dd6770c 897 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 468 479 - T 14-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 TSH58p_21270 12f3aac2a87d52563e149cba0dd6770c 897 SUPERFAMILY SSF52009 406 530 1.44E-38 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 TSH58p_21270 12f3aac2a87d52563e149cba0dd6770c 897 Pfam PF00391 PEP-utilising enzyme, mobile domain 440 521 3.5E-26 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TSH58p_14350 ae873f0409d6db6d72c82fcb92b3c732 477 SUPERFAMILY SSF53244 321 473 3.01E-44 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TSH58p_14350 ae873f0409d6db6d72c82fcb92b3c732 477 SUPERFAMILY SSF63418 9 89 1.03E-18 T 14-10-2018 IPR035911 MurE/MurF, N-terminal TSH58p_14350 ae873f0409d6db6d72c82fcb92b3c732 477 Gene3D G3DSA:3.90.190.20 330 475 5.7E-54 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TSH58p_14350 ae873f0409d6db6d72c82fcb92b3c732 477 Pfam PF01225 Mur ligase family, catalytic domain 12 60 4.1E-10 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 TSH58p_14350 ae873f0409d6db6d72c82fcb92b3c732 477 Gene3D G3DSA:3.40.1190.10 93 325 5.7E-64 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TSH58p_14350 ae873f0409d6db6d72c82fcb92b3c732 477 Pfam PF02875 Mur ligase family, glutamate ligase domain 321 406 4.3E-18 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 TSH58p_14350 ae873f0409d6db6d72c82fcb92b3c732 477 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 11 471 9.0E-131 T 14-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 TSH58p_14350 ae873f0409d6db6d72c82fcb92b3c732 477 Gene3D G3DSA:3.40.1390.10 3 90 7.2E-20 T 14-10-2018 TSH58p_14350 ae873f0409d6db6d72c82fcb92b3c732 477 Pfam PF08245 Mur ligase middle domain 98 300 2.4E-46 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 TSH58p_14350 ae873f0409d6db6d72c82fcb92b3c732 477 SUPERFAMILY SSF53623 92 320 3.32E-67 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TSH58p_14350 ae873f0409d6db6d72c82fcb92b3c732 477 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 3 471 30.861 T 14-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 TSH58p_06405 f6f23717fcc40fc1c811f20a2930bde9 380 Pfam PF13458 Periplasmic binding protein 32 355 6.1E-53 T 14-10-2018 IPR028081 Leucine-binding protein domain TSH58p_06405 f6f23717fcc40fc1c811f20a2930bde9 380 SUPERFAMILY SSF53822 33 360 3.26E-65 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_06405 f6f23717fcc40fc1c811f20a2930bde9 380 Gene3D G3DSA:3.40.50.2300 143 272 1.4E-63 T 14-10-2018 TSH58p_06405 f6f23717fcc40fc1c811f20a2930bde9 380 Gene3D G3DSA:3.40.50.2300 33 341 1.4E-63 T 14-10-2018 TSH58p_26300 d9f1e3c1bba6b34479679340725c87c9 586 SMART SM00388 348 413 5.8E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_26300 d9f1e3c1bba6b34479679340725c87c9 586 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 470 584 1.3E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_26300 d9f1e3c1bba6b34479679340725c87c9 586 Pfam PF00512 His Kinase A (phospho-acceptor) domain 350 412 2.3E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_26300 d9f1e3c1bba6b34479679340725c87c9 586 Pfam PF00672 HAMP domain 293 342 1.8E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_26300 d9f1e3c1bba6b34479679340725c87c9 586 Pfam PF13756 Stimulus-sensing domain 112 225 8.6E-28 T 14-10-2018 IPR025919 Stimulus-sensing domain TSH58p_26300 d9f1e3c1bba6b34479679340725c87c9 586 SUPERFAMILY SSF55874 403 585 5.76E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_26300 d9f1e3c1bba6b34479679340725c87c9 586 SUPERFAMILY SSF47384 334 412 5.1E-16 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_26300 d9f1e3c1bba6b34479679340725c87c9 586 SUPERFAMILY SSF158472 294 343 4.71E-5 T 14-10-2018 TSH58p_26300 d9f1e3c1bba6b34479679340725c87c9 586 Gene3D G3DSA:1.10.287.130 350 416 3.5E-12 T 14-10-2018 TSH58p_26300 d9f1e3c1bba6b34479679340725c87c9 586 SMART SM00387 469 586 2.3E-33 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_26300 d9f1e3c1bba6b34479679340725c87c9 586 Gene3D G3DSA:3.30.565.10 418 586 9.9E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_26300 d9f1e3c1bba6b34479679340725c87c9 586 SMART SM00304 292 347 4.8E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_26300 d9f1e3c1bba6b34479679340725c87c9 586 Gene3D G3DSA:1.20.1480.50 253 349 1.4E-12 T 14-10-2018 TSH58p_26300 d9f1e3c1bba6b34479679340725c87c9 586 PRINTS PR00344 Bacterial sensor protein C-terminal signature 525 535 4.5E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_26300 d9f1e3c1bba6b34479679340725c87c9 586 PRINTS PR00344 Bacterial sensor protein C-terminal signature 507 521 4.5E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_26300 d9f1e3c1bba6b34479679340725c87c9 586 PRINTS PR00344 Bacterial sensor protein C-terminal signature 571 584 4.5E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_26300 d9f1e3c1bba6b34479679340725c87c9 586 PRINTS PR00344 Bacterial sensor protein C-terminal signature 542 560 4.5E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_26300 d9f1e3c1bba6b34479679340725c87c9 586 Pfam PF13755 Sensor N-terminal transmembrane domain 38 91 6.8E-12 T 14-10-2018 IPR025908 Sensor N-terminal transmembrane domain TSH58p_31140 7e8c417bad8c904fd4bdc1f5e82d05c6 140 SUPERFAMILY SSF55298 26 138 6.13E-28 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TSH58p_31140 7e8c417bad8c904fd4bdc1f5e82d05c6 140 Pfam PF01042 Endoribonuclease L-PSP 27 135 7.0E-20 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 TSH58p_31140 7e8c417bad8c904fd4bdc1f5e82d05c6 140 Gene3D G3DSA:3.30.1330.40 5 139 2.9E-31 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TSH58p_06225 253fd8e7773020739f252298834b7531 132 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 13 129 1.7E-58 T 14-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_06225 253fd8e7773020739f252298834b7531 132 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 132 33.485 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TSH58p_06225 253fd8e7773020739f252298834b7531 132 Gene3D G3DSA:3.30.420.80 5 132 2.1E-55 T 14-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 TSH58p_06225 253fd8e7773020739f252298834b7531 132 ProSitePatterns PS00054 Ribosomal protein S11 signature. 100 122 - T 14-10-2018 IPR018102 Ribosomal S11, conserved site TSH58p_06225 253fd8e7773020739f252298834b7531 132 PIRSF PIRSF002131 1 132 4.3E-54 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TSH58p_06225 253fd8e7773020739f252298834b7531 132 Pfam PF00411 Ribosomal protein S11 22 131 1.1E-51 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TSH58p_06225 253fd8e7773020739f252298834b7531 132 SUPERFAMILY SSF53137 17 132 3.71E-50 T 14-10-2018 TSH58p_06630 cd797cbb3eb264ffe3d8e3ec7498617f 180 Pfam PF01327 Polypeptide deformylase 5 157 4.6E-48 T 14-10-2018 IPR023635 Peptide deformylase TSH58p_06630 cd797cbb3eb264ffe3d8e3ec7498617f 180 PIRSF PIRSF004749 1 178 2.5E-55 T 14-10-2018 IPR023635 Peptide deformylase TSH58p_06630 cd797cbb3eb264ffe3d8e3ec7498617f 180 SUPERFAMILY SSF56420 1 165 7.46E-57 T 14-10-2018 IPR036821 Peptide deformylase superfamily TSH58p_06630 cd797cbb3eb264ffe3d8e3ec7498617f 180 Gene3D G3DSA:3.90.45.10 1 176 4.1E-60 T 14-10-2018 IPR036821 Peptide deformylase superfamily TSH58p_06630 cd797cbb3eb264ffe3d8e3ec7498617f 180 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 162 1.7E-38 T 14-10-2018 IPR023635 Peptide deformylase TSH58p_06630 cd797cbb3eb264ffe3d8e3ec7498617f 180 PRINTS PR01576 Peptide deformylase signature 96 107 1.5E-31 T 14-10-2018 IPR023635 Peptide deformylase TSH58p_06630 cd797cbb3eb264ffe3d8e3ec7498617f 180 PRINTS PR01576 Peptide deformylase signature 127 156 1.5E-31 T 14-10-2018 IPR023635 Peptide deformylase TSH58p_06630 cd797cbb3eb264ffe3d8e3ec7498617f 180 PRINTS PR01576 Peptide deformylase signature 34 63 1.5E-31 T 14-10-2018 IPR023635 Peptide deformylase TSH58p_06630 cd797cbb3eb264ffe3d8e3ec7498617f 180 PRINTS PR01576 Peptide deformylase signature 108 126 1.5E-31 T 14-10-2018 IPR023635 Peptide deformylase TSH58p_06630 cd797cbb3eb264ffe3d8e3ec7498617f 180 Hamap MF_00163 Peptide deformylase [def]. 2 169 27.682 T 14-10-2018 IPR023635 Peptide deformylase TSH58p_06890 5329e9502b9339df302c78022f46dd9c 588 SUPERFAMILY SSF53756 328 565 4.71E-24 T 14-10-2018 TSH58p_06890 5329e9502b9339df302c78022f46dd9c 588 Gene3D G3DSA:1.25.40.10 241 312 3.4E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_06890 5329e9502b9339df302c78022f46dd9c 588 SUPERFAMILY SSF48452 11 234 6.83E-33 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_06890 5329e9502b9339df302c78022f46dd9c 588 Pfam PF13432 Tetratricopeptide repeat 247 293 7.8E-4 T 14-10-2018 TSH58p_06890 5329e9502b9339df302c78022f46dd9c 588 Pfam PF13432 Tetratricopeptide repeat 9 72 1.0E-6 T 14-10-2018 TSH58p_06890 5329e9502b9339df302c78022f46dd9c 588 Pfam PF13432 Tetratricopeptide repeat 145 207 9.9E-9 T 14-10-2018 TSH58p_06890 5329e9502b9339df302c78022f46dd9c 588 Pfam PF13432 Tetratricopeptide repeat 77 138 2.4E-4 T 14-10-2018 TSH58p_06890 5329e9502b9339df302c78022f46dd9c 588 Pfam PF13181 Tetratricopeptide repeat 208 234 0.011 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_06890 5329e9502b9339df302c78022f46dd9c 588 Gene3D G3DSA:1.25.40.10 9 170 1.8E-28 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_06890 5329e9502b9339df302c78022f46dd9c 588 SUPERFAMILY SSF48452 205 300 3.79E-14 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_06890 5329e9502b9339df302c78022f46dd9c 588 Gene3D G3DSA:1.25.40.10 171 238 6.8E-15 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_06890 5329e9502b9339df302c78022f46dd9c 588 SMART SM00028 4 37 380.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_06890 5329e9502b9339df302c78022f46dd9c 588 SMART SM00028 208 241 23.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_06890 5329e9502b9339df302c78022f46dd9c 588 SMART SM00028 174 207 4.1E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_06890 5329e9502b9339df302c78022f46dd9c 588 SMART SM00028 72 105 11.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_06890 5329e9502b9339df302c78022f46dd9c 588 SMART SM00028 106 139 11.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_06890 5329e9502b9339df302c78022f46dd9c 588 SMART SM00028 38 71 22.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_06890 5329e9502b9339df302c78022f46dd9c 588 SMART SM00028 140 173 37.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_06890 5329e9502b9339df302c78022f46dd9c 588 SMART SM00028 242 275 0.89 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_06890 5329e9502b9339df302c78022f46dd9c 588 Gene3D G3DSA:3.40.50.2000 485 566 6.6E-7 T 14-10-2018 TSH58p_21025 0ceb3f734f394b5602bfa9e30c56e1d0 160 SMART SM00448 5 129 9.9E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_21025 0ceb3f734f394b5602bfa9e30c56e1d0 160 SUPERFAMILY SSF52172 6 138 2.42E-32 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_21025 0ceb3f734f394b5602bfa9e30c56e1d0 160 Pfam PF00072 Response regulator receiver domain 7 129 6.9E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_21025 0ceb3f734f394b5602bfa9e30c56e1d0 160 Gene3D G3DSA:3.40.50.2300 2 143 2.2E-36 T 14-10-2018 TSH58p_06195 743f9cce7278781a419ec406fbe2badf 449 Gene3D G3DSA:1.10.3710.10 345 443 2.9E-32 T 14-10-2018 TSH58p_06195 743f9cce7278781a419ec406fbe2badf 449 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 59 167 1.0E-13 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSH58p_06195 743f9cce7278781a419ec406fbe2badf 449 Pfam PF12002 MgsA AAA+ ATPase C terminal 267 432 5.4E-70 T 14-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal TSH58p_06195 743f9cce7278781a419ec406fbe2badf 449 Gene3D G3DSA:1.20.272.10 240 344 5.7E-45 T 14-10-2018 TSH58p_06195 743f9cce7278781a419ec406fbe2badf 449 Gene3D G3DSA:3.40.50.300 14 169 7.2E-40 T 14-10-2018 TSH58p_06195 743f9cce7278781a419ec406fbe2badf 449 Pfam PF16193 AAA C-terminal domain 190 266 1.6E-18 T 14-10-2018 IPR032423 AAA C-terminal domain TSH58p_06195 743f9cce7278781a419ec406fbe2badf 449 SMART SM00382 55 171 2.3E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_06195 743f9cce7278781a419ec406fbe2badf 449 SUPERFAMILY SSF52540 19 224 7.58E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_06195 743f9cce7278781a419ec406fbe2badf 449 SUPERFAMILY SSF48019 252 436 9.64E-75 T 14-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 TSH58p_02710 a5f38b97c6dc3db159d5c7745cdb22bd 616 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 210 611 3.6E-86 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSH58p_02710 a5f38b97c6dc3db159d5c7745cdb22bd 616 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 201 609 2.6E-95 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TSH58p_02710 a5f38b97c6dc3db159d5c7745cdb22bd 616 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 35 159 3.3E-25 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ TSH58p_21575 295b0c86b806d572736be3cdbda247fe 173 Gene3D G3DSA:3.40.50.12280 27 173 4.5E-52 T 14-10-2018 TSH58p_21575 295b0c86b806d572736be3cdbda247fe 173 SUPERFAMILY SSF56770 40 169 4.71E-53 T 14-10-2018 TSH58p_21575 295b0c86b806d572736be3cdbda247fe 173 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 55 166 6.0E-29 T 14-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_10170 dfbafe5dd38ec928351bab6480ef1aac 535 Gene3D G3DSA:3.90.76.10 49 212 1.8E-123 T 14-10-2018 TSH58p_10170 dfbafe5dd38ec928351bab6480ef1aac 535 SUPERFAMILY SSF53850 32 533 1.01E-121 T 14-10-2018 TSH58p_10170 dfbafe5dd38ec928351bab6480ef1aac 535 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 446 1.8E-89 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain TSH58p_10170 dfbafe5dd38ec928351bab6480ef1aac 535 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 85 107 - T 14-10-2018 IPR023765 Solute-binding protein family 5, conserved site TSH58p_10170 dfbafe5dd38ec928351bab6480ef1aac 535 PIRSF PIRSF002741 3 534 1.3E-86 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TSH58p_10170 dfbafe5dd38ec928351bab6480ef1aac 535 Gene3D G3DSA:3.10.105.10 292 510 1.8E-123 T 14-10-2018 TSH58p_10170 dfbafe5dd38ec928351bab6480ef1aac 535 Gene3D G3DSA:3.40.190.10 213 522 1.8E-123 T 14-10-2018 TSH58p_02825 b39af4784e6f5aa011b1977727e8c88b 804 Pfam PF02706 Chain length determinant protein 70 154 2.6E-7 T 14-10-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 TSH58p_02825 b39af4784e6f5aa011b1977727e8c88b 804 Gene3D G3DSA:3.40.50.300 532 799 2.2E-59 T 14-10-2018 TSH58p_02825 b39af4784e6f5aa011b1977727e8c88b 804 SUPERFAMILY SSF52540 608 784 2.66E-32 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_02825 b39af4784e6f5aa011b1977727e8c88b 804 Pfam PF13614 AAA domain 621 768 3.6E-8 T 14-10-2018 IPR025669 AAA domain TSH58p_02540 cd0acd437feeac96fb4b6789609411b6 586 SUPERFAMILY SSF55073 421 578 3.14E-51 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_02540 cd0acd437feeac96fb4b6789609411b6 586 Gene3D G3DSA:3.30.70.270 412 583 1.8E-58 T 14-10-2018 TSH58p_02540 cd0acd437feeac96fb4b6789609411b6 586 SMART SM00267 405 577 5.5E-63 T 14-10-2018 IPR000160 GGDEF domain TSH58p_02540 cd0acd437feeac96fb4b6789609411b6 586 Gene3D G3DSA:3.30.450.20 281 411 1.6E-27 T 14-10-2018 TSH58p_02540 cd0acd437feeac96fb4b6789609411b6 586 Gene3D G3DSA:3.30.450.20 150 280 2.2E-21 T 14-10-2018 TSH58p_02540 cd0acd437feeac96fb4b6789609411b6 586 SMART SM00086 230 272 0.079 T 14-10-2018 IPR001610 PAC motif TSH58p_02540 cd0acd437feeac96fb4b6789609411b6 586 SMART SM00086 356 398 0.033 T 14-10-2018 IPR001610 PAC motif TSH58p_02540 cd0acd437feeac96fb4b6789609411b6 586 Pfam PF08448 PAS fold 169 274 1.5E-15 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_02540 cd0acd437feeac96fb4b6789609411b6 586 Pfam PF08448 PAS fold 291 399 7.8E-21 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_02540 cd0acd437feeac96fb4b6789609411b6 586 SUPERFAMILY SSF55785 155 270 1.05E-18 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_02540 cd0acd437feeac96fb4b6789609411b6 586 Pfam PF13188 PAS domain 53 96 0.16 T 14-10-2018 IPR000014 PAS domain TSH58p_02540 cd0acd437feeac96fb4b6789609411b6 586 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 160 279 7.2E-15 T 14-10-2018 IPR000014 PAS domain TSH58p_02540 cd0acd437feeac96fb4b6789609411b6 586 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 283 405 5.5E-18 T 14-10-2018 IPR000014 PAS domain TSH58p_02540 cd0acd437feeac96fb4b6789609411b6 586 SUPERFAMILY SSF55785 269 396 2.27E-28 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_02540 cd0acd437feeac96fb4b6789609411b6 586 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 414 575 4.6E-44 T 14-10-2018 IPR000160 GGDEF domain TSH58p_02540 cd0acd437feeac96fb4b6789609411b6 586 SMART SM00091 284 350 1.5E-4 T 14-10-2018 IPR000014 PAS domain TSH58p_02540 cd0acd437feeac96fb4b6789609411b6 586 SMART SM00091 162 229 0.017 T 14-10-2018 IPR000014 PAS domain TSH58p_02540 cd0acd437feeac96fb4b6789609411b6 586 Pfam PF00990 Diguanylate cyclase, GGDEF domain 416 572 9.2E-50 T 14-10-2018 IPR000160 GGDEF domain TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 Pfam PF00989 PAS fold 392 507 3.3E-17 T 14-10-2018 IPR013767 PAS fold GO:0006355 TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 Gene3D G3DSA:3.30.450.20 212 319 1.5E-11 T 14-10-2018 TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 SUPERFAMILY SSF52172 948 1069 3.27E-38 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 391 517 1.5E-19 T 14-10-2018 IPR000014 PAS domain TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 SUPERFAMILY SSF55874 584 753 5.37E-44 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 Gene3D G3DSA:3.30.450.20 389 520 6.9E-31 T 14-10-2018 TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 SUPERFAMILY SSF47384 515 596 4.12E-21 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 SUPERFAMILY SSF52172 784 914 1.57E-26 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 Gene3D G3DSA:1.20.120.160 1105 1214 7.2E-13 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 Gene3D G3DSA:3.30.450.20 59 209 2.5E-29 T 14-10-2018 TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 SMART SM00388 530 595 3.9E-25 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 Gene3D G3DSA:3.30.565.10 596 758 2.4E-49 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 SMART SM00448 786 909 3.0E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 SMART SM00448 949 1064 2.1E-38 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 Gene3D G3DSA:1.10.287.130 521 595 8.3E-26 T 14-10-2018 TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 Pfam PF00512 His Kinase A (phospho-acceptor) domain 530 595 4.3E-20 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 PRINTS PR00344 Bacterial sensor protein C-terminal signature 683 697 3.4E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 PRINTS PR00344 Bacterial sensor protein C-terminal signature 701 711 3.4E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 PRINTS PR00344 Bacterial sensor protein C-terminal signature 742 755 3.4E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 PRINTS PR00344 Bacterial sensor protein C-terminal signature 718 736 3.4E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 Gene3D G3DSA:3.40.50.12740 948 1104 4.1E-44 T 14-10-2018 TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 Gene3D G3DSA:3.40.50.12740 786 932 1.3E-27 T 14-10-2018 TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 SUPERFAMILY SSF55785 402 519 2.44E-24 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 SMART SM00091 391 457 5.5E-12 T 14-10-2018 IPR000014 PAS domain TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 642 755 2.0E-30 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 Pfam PF00072 Response regulator receiver domain 788 909 3.6E-17 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 Pfam PF00072 Response regulator receiver domain 952 1064 2.3E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 SUPERFAMILY SSF47226 1047 1205 1.57E-17 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_12685 68080b7f1b3698d4efc69c719d136a72 1313 SMART SM00387 642 758 1.4E-36 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_21140 d8de885c6681109e8408cb31f6525d69 325 SUPERFAMILY SSF161098 89 305 1.59E-16 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_21140 d8de885c6681109e8408cb31f6525d69 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 319 2.8E-36 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_21140 d8de885c6681109e8408cb31f6525d69 325 Gene3D G3DSA:1.10.3720.10 84 314 3.0E-21 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_29515 b49b911efc5a1e2186531f310dff430a 279 SUPERFAMILY SSF53335 8 274 6.51E-92 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_29515 b49b911efc5a1e2186531f310dff430a 279 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 1 265 41.017 T 14-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 TSH58p_29515 b49b911efc5a1e2186531f310dff430a 279 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 34 276 2.0E-94 T 14-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 TSH58p_29515 b49b911efc5a1e2186531f310dff430a 279 Gene3D G3DSA:3.40.50.150 1 279 2.2E-107 T 14-10-2018 TSH58p_27605 28cc683db1cff5864b563d47ad832860 174 Pfam PF01381 Helix-turn-helix 23 75 3.3E-13 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_27605 28cc683db1cff5864b563d47ad832860 174 Gene3D G3DSA:1.10.260.40 13 85 4.4E-17 T 14-10-2018 TSH58p_27605 28cc683db1cff5864b563d47ad832860 174 SMART SM00530 22 77 2.3E-14 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_27605 28cc683db1cff5864b563d47ad832860 174 SUPERFAMILY SSF47413 12 88 3.07E-24 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_29005 77d5204b1dcdecc67bff0f763dc7dc47 364 Pfam PF02615 Malate/L-lactate dehydrogenase 7 347 2.2E-96 T 14-10-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0016491|GO:0055114 TSH58p_29005 77d5204b1dcdecc67bff0f763dc7dc47 364 SUPERFAMILY SSF89733 6 356 1.02E-84 T 14-10-2018 IPR036111 Malate/L-sulfolactate/L-lactate dehydrogenase-like superfamily GO:0016491|GO:0055114 TSH58p_29005 77d5204b1dcdecc67bff0f763dc7dc47 364 Gene3D G3DSA:3.30.1370.60 69 321 9.0E-95 T 14-10-2018 TSH58p_29005 77d5204b1dcdecc67bff0f763dc7dc47 364 Gene3D G3DSA:1.10.1530.10 16 351 9.0E-95 T 14-10-2018 TSH58p_13215 0ab7abc808e53be1daf5a8fbe8e3d5d2 168 PRINTS PR01576 Peptide deformylase signature 92 103 9.9E-37 T 14-10-2018 IPR023635 Peptide deformylase TSH58p_13215 0ab7abc808e53be1daf5a8fbe8e3d5d2 168 PRINTS PR01576 Peptide deformylase signature 123 152 9.9E-37 T 14-10-2018 IPR023635 Peptide deformylase TSH58p_13215 0ab7abc808e53be1daf5a8fbe8e3d5d2 168 PRINTS PR01576 Peptide deformylase signature 33 62 9.9E-37 T 14-10-2018 IPR023635 Peptide deformylase TSH58p_13215 0ab7abc808e53be1daf5a8fbe8e3d5d2 168 PRINTS PR01576 Peptide deformylase signature 104 122 9.9E-37 T 14-10-2018 IPR023635 Peptide deformylase TSH58p_13215 0ab7abc808e53be1daf5a8fbe8e3d5d2 168 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 162 2.6E-59 T 14-10-2018 IPR023635 Peptide deformylase TSH58p_13215 0ab7abc808e53be1daf5a8fbe8e3d5d2 168 Pfam PF01327 Polypeptide deformylase 4 155 3.2E-56 T 14-10-2018 IPR023635 Peptide deformylase TSH58p_13215 0ab7abc808e53be1daf5a8fbe8e3d5d2 168 SUPERFAMILY SSF56420 2 167 1.27E-64 T 14-10-2018 IPR036821 Peptide deformylase superfamily TSH58p_13215 0ab7abc808e53be1daf5a8fbe8e3d5d2 168 Hamap MF_00163 Peptide deformylase [def]. 2 165 31.808 T 14-10-2018 IPR023635 Peptide deformylase TSH58p_13215 0ab7abc808e53be1daf5a8fbe8e3d5d2 168 Gene3D G3DSA:3.90.45.10 1 168 1.0E-64 T 14-10-2018 IPR036821 Peptide deformylase superfamily TSH58p_13215 0ab7abc808e53be1daf5a8fbe8e3d5d2 168 PIRSF PIRSF004749 1 168 5.1E-62 T 14-10-2018 IPR023635 Peptide deformylase TSH58p_13985 5deb0155e3c02e295c47de0fd1fa5ad8 648 PIRSF PIRSF000549 1 648 2.6E-285 T 14-10-2018 IPR016230 Serine-protein kinase, PrkA GO:0004672 TSH58p_13985 5deb0155e3c02e295c47de0fd1fa5ad8 648 SUPERFAMILY SSF52540 79 353 3.36E-18 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_13985 5deb0155e3c02e295c47de0fd1fa5ad8 648 Pfam PF08298 PrkA AAA domain 23 383 4.2E-176 T 14-10-2018 IPR013153 PrkA AAA domain TSH58p_13985 5deb0155e3c02e295c47de0fd1fa5ad8 648 Pfam PF06798 PrkA serine protein kinase C-terminal domain 387 640 2.8E-75 T 14-10-2018 IPR010650 PrkA C-terminal domain TSH58p_13985 5deb0155e3c02e295c47de0fd1fa5ad8 648 SMART SM00763 23 384 8.8E-204 T 14-10-2018 IPR013153 PrkA AAA domain TSH58p_12345 331e1358f83988c4618d026bebc740f5 306 SUPERFAMILY SSF103481 62 163 6.02E-10 T 14-10-2018 TSH58p_12345 331e1358f83988c4618d026bebc740f5 306 Pfam PF00892 EamA-like transporter family 170 293 1.5E-6 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_12345 331e1358f83988c4618d026bebc740f5 306 Pfam PF00892 EamA-like transporter family 31 159 7.6E-8 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_12345 331e1358f83988c4618d026bebc740f5 306 SUPERFAMILY SSF103481 203 302 1.7E-10 T 14-10-2018 TSH58p_06650 40cf03db4aa09f9dda89ba492b21e42e 464 Gene3D G3DSA:3.40.50.1220 287 464 7.5E-85 T 14-10-2018 TSH58p_06650 40cf03db4aa09f9dda89ba492b21e42e 464 PIRSF PIRSF000204 1 464 1.2E-218 T 14-10-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 TSH58p_06650 40cf03db4aa09f9dda89ba492b21e42e 464 Pfam PF02233 NAD(P) transhydrogenase beta subunit 7 461 6.6E-200 T 14-10-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 TSH58p_06650 40cf03db4aa09f9dda89ba492b21e42e 464 SUPERFAMILY SSF52467 290 463 3.11E-76 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TSH58p_07710 22974bd81ad582d43aefbd641b9165c3 126 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 14-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 TSH58p_07710 22974bd81ad582d43aefbd641b9165c3 126 Gene3D G3DSA:2.60.300.12 1 108 8.2E-32 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 TSH58p_07710 22974bd81ad582d43aefbd641b9165c3 126 SUPERFAMILY SSF89360 1 96 1.73E-27 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 TSH58p_07710 22974bd81ad582d43aefbd641b9165c3 126 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 103 2.2E-24 T 14-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 TSH58p_07710 22974bd81ad582d43aefbd641b9165c3 126 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 2 106 1.8E-36 T 14-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 TSH58p_10560 f1812fa28279cfdf0eed7b59673c20e7 539 Pfam PF00072 Response regulator receiver domain 40 148 1.0E-6 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_10560 f1812fa28279cfdf0eed7b59673c20e7 539 Gene3D G3DSA:3.40.50.2300 38 177 4.8E-13 T 14-10-2018 TSH58p_10560 f1812fa28279cfdf0eed7b59673c20e7 539 Gene3D G3DSA:1.10.3210.10 332 535 2.6E-69 T 14-10-2018 TSH58p_10560 f1812fa28279cfdf0eed7b59673c20e7 539 SUPERFAMILY SSF109604 344 533 2.46E-34 T 14-10-2018 TSH58p_10560 f1812fa28279cfdf0eed7b59673c20e7 539 SMART SM00471 352 502 1.4E-9 T 14-10-2018 IPR003607 HD/PDEase domain TSH58p_10560 f1812fa28279cfdf0eed7b59673c20e7 539 Pfam PF01966 HD domain 357 492 4.5E-16 T 14-10-2018 IPR006674 HD domain TSH58p_10560 f1812fa28279cfdf0eed7b59673c20e7 539 Pfam PF11849 Domain of unknown function (DUF3369) 160 334 1.1E-39 T 14-10-2018 IPR021800 Domain of unknown function DUF3369 TSH58p_10560 f1812fa28279cfdf0eed7b59673c20e7 539 SUPERFAMILY SSF52172 36 187 6.83E-13 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_02055 0080a82637269102dcd68a75a2ba6660 1077 Gene3D G3DSA:3.30.70.1430 581 689 2.7E-217 T 14-10-2018 TSH58p_02055 0080a82637269102dcd68a75a2ba6660 1077 SUPERFAMILY SSF82866 830 1063 6.41E-42 T 14-10-2018 TSH58p_02055 0080a82637269102dcd68a75a2ba6660 1077 SUPERFAMILY SSF82693 45 138 8.37E-16 T 14-10-2018 TSH58p_02055 0080a82637269102dcd68a75a2ba6660 1077 SUPERFAMILY SSF82866 307 509 1.23E-38 T 14-10-2018 TSH58p_02055 0080a82637269102dcd68a75a2ba6660 1077 Gene3D G3DSA:3.30.70.1430 45 837 2.7E-217 T 14-10-2018 TSH58p_02055 0080a82637269102dcd68a75a2ba6660 1077 Gene3D G3DSA:1.20.1640.10 529 1059 2.7E-217 T 14-10-2018 TSH58p_02055 0080a82637269102dcd68a75a2ba6660 1077 SUPERFAMILY SSF82693 579 678 1.07E-8 T 14-10-2018 TSH58p_02055 0080a82637269102dcd68a75a2ba6660 1077 PRINTS PR00702 Acriflavin resistance protein family signature 482 505 1.3E-25 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_02055 0080a82637269102dcd68a75a2ba6660 1077 PRINTS PR00702 Acriflavin resistance protein family signature 43 61 1.3E-25 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_02055 0080a82637269102dcd68a75a2ba6660 1077 PRINTS PR00702 Acriflavin resistance protein family signature 374 395 1.3E-25 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_02055 0080a82637269102dcd68a75a2ba6660 1077 PRINTS PR00702 Acriflavin resistance protein family signature 402 426 1.3E-25 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_02055 0080a82637269102dcd68a75a2ba6660 1077 PRINTS PR00702 Acriflavin resistance protein family signature 457 480 1.3E-25 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_02055 0080a82637269102dcd68a75a2ba6660 1077 PRINTS PR00702 Acriflavin resistance protein family signature 15 39 1.3E-25 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_02055 0080a82637269102dcd68a75a2ba6660 1077 Gene3D G3DSA:1.20.1640.10 20 527 2.7E-217 T 14-10-2018 TSH58p_02055 0080a82637269102dcd68a75a2ba6660 1077 Gene3D G3DSA:3.30.2090.10 187 277 2.7E-217 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_02055 0080a82637269102dcd68a75a2ba6660 1077 Gene3D G3DSA:3.30.70.1320 139 344 2.7E-217 T 14-10-2018 TSH58p_02055 0080a82637269102dcd68a75a2ba6660 1077 Pfam PF00873 AcrB/AcrD/AcrF family 11 851 9.6E-106 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_02055 0080a82637269102dcd68a75a2ba6660 1077 Pfam PF00873 AcrB/AcrD/AcrF family 910 1062 2.0E-32 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_02055 0080a82637269102dcd68a75a2ba6660 1077 Gene3D G3DSA:3.30.70.1440 690 907 2.7E-217 T 14-10-2018 TSH58p_02055 0080a82637269102dcd68a75a2ba6660 1077 Gene3D G3DSA:3.30.2090.10 740 829 2.7E-217 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_02055 0080a82637269102dcd68a75a2ba6660 1077 SUPERFAMILY SSF82693 156 339 4.45E-8 T 14-10-2018 TSH58p_02055 0080a82637269102dcd68a75a2ba6660 1077 SUPERFAMILY SSF82714 192 273 2.22E-14 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_22820 8d5e65c7bc3bce8e36d8bb1785fa5381 339 Gene3D G3DSA:3.40.50.1580 65 313 2.0E-13 T 14-10-2018 TSH58p_22820 8d5e65c7bc3bce8e36d8bb1785fa5381 339 SUPERFAMILY SSF53167 83 260 2.72E-7 T 14-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TSH58p_22820 8d5e65c7bc3bce8e36d8bb1785fa5381 339 Pfam PF06516 Purine nucleoside permease (NUP) 31 334 1.2E-76 T 14-10-2018 IPR009486 Purine nucleoside permease GO:0055085 TSH58p_22820 8d5e65c7bc3bce8e36d8bb1785fa5381 339 PIRSF PIRSF013171 2 338 1.1E-62 T 14-10-2018 IPR009486 Purine nucleoside permease GO:0055085 TSH58p_05965 4d2bca9633a8ce732b697ff52434b4b4 487 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 226 480 1.1E-57 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 TSH58p_05965 4d2bca9633a8ce732b697ff52434b4b4 487 PIRSF PIRSF017184 3 485 2.5E-105 T 14-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 TSH58p_05965 4d2bca9633a8ce732b697ff52434b4b4 487 Pfam PF01256 Carbohydrate kinase 239 462 8.9E-49 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 TSH58p_05965 4d2bca9633a8ce732b697ff52434b4b4 487 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 6 200 24.185 T 14-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TSH58p_05965 4d2bca9633a8ce732b697ff52434b4b4 487 SUPERFAMILY SSF64153 4 237 6.02E-59 T 14-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 TSH58p_05965 4d2bca9633a8ce732b697ff52434b4b4 487 Pfam PF03853 YjeF-related protein N-terminus 26 179 9.5E-34 T 14-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TSH58p_05965 4d2bca9633a8ce732b697ff52434b4b4 487 SUPERFAMILY SSF53613 213 481 2.62E-62 T 14-10-2018 IPR029056 Ribokinase-like TSH58p_05965 4d2bca9633a8ce732b697ff52434b4b4 487 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 8 200 1.1E-36 T 14-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TSH58p_05965 4d2bca9633a8ce732b697ff52434b4b4 487 Gene3D G3DSA:3.40.1190.20 216 486 3.9E-72 T 14-10-2018 IPR029056 Ribokinase-like TSH58p_05965 4d2bca9633a8ce732b697ff52434b4b4 487 Gene3D G3DSA:3.40.50.10260 3 207 4.3E-59 T 14-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 TSH58p_05965 4d2bca9633a8ce732b697ff52434b4b4 487 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 215 484 19.245 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 TSH58p_27715 ad9c8e8746bee1f542d5484bbab4588c 691 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 156 609 3.6E-123 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TSH58p_27715 ad9c8e8746bee1f542d5484bbab4588c 691 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 49 684 2.3E-228 T 14-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ TSH58p_18440 7e3e8b68874519ea682503764070d104 365 Gene3D G3DSA:3.40.50.720 304 365 3.6E-12 T 14-10-2018 TSH58p_18440 7e3e8b68874519ea682503764070d104 365 SUPERFAMILY SSF51971 1 363 2.88E-46 T 14-10-2018 TSH58p_18440 7e3e8b68874519ea682503764070d104 365 Gene3D G3DSA:3.40.50.720 130 261 8.9E-20 T 14-10-2018 TSH58p_18440 7e3e8b68874519ea682503764070d104 365 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 1 360 3.5E-110 T 14-10-2018 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 TSH58p_18440 7e3e8b68874519ea682503764070d104 365 Pfam PF03275 UDP-galactopyranose mutase 146 345 2.2E-68 T 14-10-2018 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 TSH58p_18440 7e3e8b68874519ea682503764070d104 365 Gene3D G3DSA:3.40.50.720 1 99 2.3E-29 T 14-10-2018 TSH58p_18440 7e3e8b68874519ea682503764070d104 365 SUPERFAMILY SSF54373 244 312 1.02E-20 T 14-10-2018 TSH58p_18440 7e3e8b68874519ea682503764070d104 365 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 72 2.5E-19 T 14-10-2018 TSH58p_18675 30358dc38dc503f2d5da7f68e87cab67 514 Gene3D G3DSA:1.10.1060.10 235 313 3.6E-5 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSH58p_18675 30358dc38dc503f2d5da7f68e87cab67 514 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 379 514 3.6E-24 T 14-10-2018 IPR032879 FixG, C-terminal immunoglobulin-like domain TSH58p_18675 30358dc38dc503f2d5da7f68e87cab67 514 Gene3D G3DSA:2.60.40.10 382 456 1.6E-14 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_18675 30358dc38dc503f2d5da7f68e87cab67 514 Pfam PF12801 4Fe-4S binding domain 112 154 3.6E-10 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_18675 30358dc38dc503f2d5da7f68e87cab67 514 Pfam PF13746 4Fe-4S dicluster domain 234 342 3.1E-44 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_18675 30358dc38dc503f2d5da7f68e87cab67 514 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 290 301 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_18675 30358dc38dc503f2d5da7f68e87cab67 514 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 51 512 1.7E-149 T 14-10-2018 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021|GO:0055114 TSH58p_18675 30358dc38dc503f2d5da7f68e87cab67 514 SUPERFAMILY SSF54862 121 372 2.76E-28 T 14-10-2018 TSH58p_04250 4359a3e515d8f753303cfb6e9a39b164 393 PRINTS PR01270 Histone deacetylase superfamily signature 149 172 1.3E-17 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSH58p_04250 4359a3e515d8f753303cfb6e9a39b164 393 PRINTS PR01270 Histone deacetylase superfamily signature 262 272 1.3E-17 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSH58p_04250 4359a3e515d8f753303cfb6e9a39b164 393 PRINTS PR01270 Histone deacetylase superfamily signature 182 197 1.3E-17 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSH58p_04250 4359a3e515d8f753303cfb6e9a39b164 393 Gene3D G3DSA:3.40.800.20 23 389 4.3E-93 T 14-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSH58p_04250 4359a3e515d8f753303cfb6e9a39b164 393 SUPERFAMILY SSF52768 25 380 1.06E-86 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily TSH58p_04250 4359a3e515d8f753303cfb6e9a39b164 393 Pfam PF00850 Histone deacetylase domain 49 327 5.8E-60 T 14-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSH58p_32575 17d94b2c70181bdccee60854011af400 401 SUPERFAMILY SSF55424 309 399 3.43E-30 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TSH58p_32575 17d94b2c70181bdccee60854011af400 401 Gene3D G3DSA:3.30.390.30 316 400 9.9E-36 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TSH58p_32575 17d94b2c70181bdccee60854011af400 401 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 297 5.8E-61 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSH58p_32575 17d94b2c70181bdccee60854011af400 401 Gene3D G3DSA:3.50.50.60 2 304 1.2E-105 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_32575 17d94b2c70181bdccee60854011af400 401 SUPERFAMILY SSF51905 2 307 3.7E-45 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_32575 17d94b2c70181bdccee60854011af400 401 Pfam PF14759 Reductase C-terminal 316 399 5.6E-33 T 14-10-2018 IPR028202 Reductase, C-terminal TSH58p_32575 17d94b2c70181bdccee60854011af400 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 7.8E-26 T 14-10-2018 TSH58p_32575 17d94b2c70181bdccee60854011af400 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 7.8E-26 T 14-10-2018 TSH58p_32575 17d94b2c70181bdccee60854011af400 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 7.8E-26 T 14-10-2018 TSH58p_32575 17d94b2c70181bdccee60854011af400 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 97 115 7.8E-26 T 14-10-2018 TSH58p_32575 17d94b2c70181bdccee60854011af400 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 1 14 7.8E-26 T 14-10-2018 TSH58p_32575 17d94b2c70181bdccee60854011af400 401 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 4.0E-15 T 14-10-2018 TSH58p_32575 17d94b2c70181bdccee60854011af400 401 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 229 243 4.0E-15 T 14-10-2018 TSH58p_32575 17d94b2c70181bdccee60854011af400 401 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 142 167 4.0E-15 T 14-10-2018 TSH58p_32575 17d94b2c70181bdccee60854011af400 401 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 100 109 4.0E-15 T 14-10-2018 TSH58p_32575 17d94b2c70181bdccee60854011af400 401 Gene3D G3DSA:3.50.50.60 110 235 1.2E-105 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_27710 a74ef6a9a416c4c13a850c38337efd03 328 Gene3D G3DSA:3.40.190.10 124 260 1.5E-108 T 14-10-2018 TSH58p_27710 a74ef6a9a416c4c13a850c38337efd03 328 SUPERFAMILY SSF53850 31 327 6.49E-72 T 14-10-2018 TSH58p_27710 a74ef6a9a416c4c13a850c38337efd03 328 Gene3D G3DSA:3.40.190.10 36 325 1.5E-108 T 14-10-2018 TSH58p_27710 a74ef6a9a416c4c13a850c38337efd03 328 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 8 325 7.1E-109 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family TSH58p_27710 a74ef6a9a416c4c13a850c38337efd03 328 Pfam PF16868 NMT1-like family 36 325 4.0E-93 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family TSH58p_26835 25632cbbb3badc2551dfa7b5ec96ef98 273 SUPERFAMILY SSF161098 74 259 8.5E-30 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_26835 25632cbbb3badc2551dfa7b5ec96ef98 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 260 8.5E-24 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_26835 25632cbbb3badc2551dfa7b5ec96ef98 273 Gene3D G3DSA:1.10.3720.10 75 269 2.4E-24 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_25060 e9cb0f4ba7358ff9a09928eb4feca065 580 SUPERFAMILY SSF48452 275 407 1.03E-14 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25060 e9cb0f4ba7358ff9a09928eb4feca065 580 Pfam PF13432 Tetratricopeptide repeat 420 483 0.01 T 14-10-2018 TSH58p_25060 e9cb0f4ba7358ff9a09928eb4feca065 580 Pfam PF13432 Tetratricopeptide repeat 348 406 3.5E-6 T 14-10-2018 TSH58p_25060 e9cb0f4ba7358ff9a09928eb4feca065 580 SMART SM00028 344 377 96.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25060 e9cb0f4ba7358ff9a09928eb4feca065 580 SMART SM00028 485 518 1.3 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25060 e9cb0f4ba7358ff9a09928eb4feca065 580 SMART SM00028 416 449 0.09 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25060 e9cb0f4ba7358ff9a09928eb4feca065 580 SMART SM00028 450 484 19.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25060 e9cb0f4ba7358ff9a09928eb4feca065 580 SMART SM00028 46 79 470.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25060 e9cb0f4ba7358ff9a09928eb4feca065 580 SMART SM00028 378 411 0.024 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25060 e9cb0f4ba7358ff9a09928eb4feca065 580 SMART SM00028 519 552 170.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25060 e9cb0f4ba7358ff9a09928eb4feca065 580 SMART SM00028 276 309 100.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25060 e9cb0f4ba7358ff9a09928eb4feca065 580 Gene3D G3DSA:1.25.40.10 255 409 1.3E-15 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25060 e9cb0f4ba7358ff9a09928eb4feca065 580 SUPERFAMILY SSF48452 375 548 1.97E-32 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25060 e9cb0f4ba7358ff9a09928eb4feca065 580 SUPERFAMILY SSF48452 51 332 1.59E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25060 e9cb0f4ba7358ff9a09928eb4feca065 580 Gene3D G3DSA:1.25.40.10 498 565 3.8E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25060 e9cb0f4ba7358ff9a09928eb4feca065 580 Pfam PF13414 TPR repeat 494 533 1.0E-8 T 14-10-2018 TSH58p_25060 e9cb0f4ba7358ff9a09928eb4feca065 580 Gene3D G3DSA:1.25.40.10 410 497 4.0E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25060 e9cb0f4ba7358ff9a09928eb4feca065 580 Gene3D G3DSA:1.25.40.10 45 254 5.1E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_18810 351377a117b0ead2b6b29d88d7fd93e4 354 SUPERFAMILY SSF55021 250 345 3.2E-24 T 14-10-2018 TSH58p_18810 351377a117b0ead2b6b29d88d7fd93e4 354 Pfam PF09383 NIL domain 270 341 2.0E-22 T 14-10-2018 IPR018449 NIL domain TSH58p_18810 351377a117b0ead2b6b29d88d7fd93e4 354 Pfam PF00005 ABC transporter 23 171 1.8E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_18810 351377a117b0ead2b6b29d88d7fd93e4 354 SMART SM00930 267 342 1.8E-23 T 14-10-2018 IPR018449 NIL domain TSH58p_18810 351377a117b0ead2b6b29d88d7fd93e4 354 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_18810 351377a117b0ead2b6b29d88d7fd93e4 354 SUPERFAMILY SSF52540 1 242 2.59E-82 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_18810 351377a117b0ead2b6b29d88d7fd93e4 354 SMART SM00382 32 220 1.2E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_18810 351377a117b0ead2b6b29d88d7fd93e4 354 Gene3D G3DSA:3.40.50.300 1 234 2.3E-74 T 14-10-2018 TSH58p_18810 351377a117b0ead2b6b29d88d7fd93e4 354 Gene3D G3DSA:3.30.70.260 235 345 2.0E-30 T 14-10-2018 TSH58p_04705 6d55c29740b96200e85a986ebbd44f4f 660 Pfam PF01541 GIY-YIG catalytic domain 66 140 9.0E-7 T 14-10-2018 IPR000305 GIY-YIG endonuclease TSH58p_04705 6d55c29740b96200e85a986ebbd44f4f 660 SUPERFAMILY SSF46600 238 290 2.88E-12 T 14-10-2018 IPR036876 UVR domain superfamily TSH58p_04705 6d55c29740b96200e85a986ebbd44f4f 660 SMART SM00278 636 655 0.73 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TSH58p_04705 6d55c29740b96200e85a986ebbd44f4f 660 SMART SM00278 604 623 64.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TSH58p_04705 6d55c29740b96200e85a986ebbd44f4f 660 Pfam PF02151 UvrB/uvrC motif 259 283 5.6E-9 T 14-10-2018 IPR001943 UVR domain GO:0005515 TSH58p_04705 6d55c29740b96200e85a986ebbd44f4f 660 Gene3D G3DSA:3.30.420.340 422 597 1.5E-48 T 14-10-2018 IPR038476 UvrC homology region 2 superfamily TSH58p_04705 6d55c29740b96200e85a986ebbd44f4f 660 SUPERFAMILY SSF47781 573 658 9.85E-23 T 14-10-2018 IPR010994 RuvA domain 2-like TSH58p_04705 6d55c29740b96200e85a986ebbd44f4f 660 Gene3D G3DSA:1.10.150.20 598 656 1.1E-18 T 14-10-2018 TSH58p_04705 6d55c29740b96200e85a986ebbd44f4f 660 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 430 590 6.1E-51 T 14-10-2018 IPR001162 UvrC family homology region TSH58p_04705 6d55c29740b96200e85a986ebbd44f4f 660 Hamap MF_00203 UvrABC system protein C [uvrC]. 51 655 27.036 T 14-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 TSH58p_04705 6d55c29740b96200e85a986ebbd44f4f 660 SUPERFAMILY SSF82771 64 147 2.75E-18 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 TSH58p_04705 6d55c29740b96200e85a986ebbd44f4f 660 Gene3D G3DSA:3.40.1440.10 51 149 3.9E-30 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 TSH58p_04705 6d55c29740b96200e85a986ebbd44f4f 660 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 56 634 6.4E-165 T 14-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 TSH58p_04705 6d55c29740b96200e85a986ebbd44f4f 660 Pfam PF12826 Helix-hairpin-helix motif 609 659 1.2E-6 T 14-10-2018 TSH58p_04705 6d55c29740b96200e85a986ebbd44f4f 660 SMART SM00465 64 145 5.0E-15 T 14-10-2018 IPR000305 GIY-YIG endonuclease TSH58p_17880 50ecda0729a7f77ae0531ec6afb62993 481 Pfam PF09913 Predicted membrane protein (DUF2142) 32 426 5.3E-49 T 14-10-2018 IPR018674 Protein of unknown function DUF2142, membrane TSH58p_16535 9f4e87d113cfa1be43bd1ab101192de8 485 PRINTS PR00147 DNA photolyase signature 144 160 4.4E-24 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 TSH58p_16535 9f4e87d113cfa1be43bd1ab101192de8 485 PRINTS PR00147 DNA photolyase signature 387 401 4.4E-24 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 TSH58p_16535 9f4e87d113cfa1be43bd1ab101192de8 485 PRINTS PR00147 DNA photolyase signature 328 344 4.4E-24 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 TSH58p_16535 9f4e87d113cfa1be43bd1ab101192de8 485 PRINTS PR00147 DNA photolyase signature 348 366 4.4E-24 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 TSH58p_16535 9f4e87d113cfa1be43bd1ab101192de8 485 Pfam PF03441 FAD binding domain of DNA photolyase 279 478 1.7E-88 T 14-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 TSH58p_16535 9f4e87d113cfa1be43bd1ab101192de8 485 Gene3D G3DSA:3.40.50.620 9 209 1.6E-100 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_16535 9f4e87d113cfa1be43bd1ab101192de8 485 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 328 340 - T 14-10-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal TSH58p_16535 9f4e87d113cfa1be43bd1ab101192de8 485 SUPERFAMILY SSF48173 196 482 4.06E-115 T 14-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 TSH58p_16535 9f4e87d113cfa1be43bd1ab101192de8 485 Pfam PF00875 DNA photolyase 9 169 6.5E-51 T 14-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 TSH58p_16535 9f4e87d113cfa1be43bd1ab101192de8 485 Gene3D G3DSA:1.25.40.80 133 293 1.6E-100 T 14-10-2018 TSH58p_16535 9f4e87d113cfa1be43bd1ab101192de8 485 Gene3D G3DSA:1.10.579.10 298 484 1.5E-85 T 14-10-2018 TSH58p_16535 9f4e87d113cfa1be43bd1ab101192de8 485 SUPERFAMILY SSF52425 7 211 3.14E-59 T 14-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 TSH58p_15265 392e615906d4de4ce30a744ff3c2f95a 446 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 24 432 2.2E-128 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSH58p_15265 392e615906d4de4ce30a744ff3c2f95a 446 Hamap MF_01465 Protein translocase subunit SecY [secY]. 14 437 29.493 T 14-10-2018 IPR026593 Protein translocase subunit SecY TSH58p_15265 392e615906d4de4ce30a744ff3c2f95a 446 Pfam PF00344 SecY translocase 80 421 1.3E-116 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSH58p_15265 392e615906d4de4ce30a744ff3c2f95a 446 ProSitePatterns PS00756 Protein secY signature 2. 178 195 - T 14-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSH58p_15265 392e615906d4de4ce30a744ff3c2f95a 446 SUPERFAMILY SSF103491 17 428 8.76E-131 T 14-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSH58p_15265 392e615906d4de4ce30a744ff3c2f95a 446 Gene3D G3DSA:1.10.3370.10 13 433 3.1E-160 T 14-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSH58p_15265 392e615906d4de4ce30a744ff3c2f95a 446 PIRSF PIRSF004557 11 445 1.6E-120 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSH58p_15265 392e615906d4de4ce30a744ff3c2f95a 446 ProSitePatterns PS00755 Protein secY signature 1. 80 99 - T 14-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSH58p_15265 392e615906d4de4ce30a744ff3c2f95a 446 PRINTS PR00303 Preprotein translocase SecY subunit signature 406 424 2.7E-96 T 14-10-2018 TSH58p_15265 392e615906d4de4ce30a744ff3c2f95a 446 PRINTS PR00303 Preprotein translocase SecY subunit signature 120 143 2.7E-96 T 14-10-2018 TSH58p_15265 392e615906d4de4ce30a744ff3c2f95a 446 PRINTS PR00303 Preprotein translocase SecY subunit signature 185 208 2.7E-96 T 14-10-2018 TSH58p_15265 392e615906d4de4ce30a744ff3c2f95a 446 PRINTS PR00303 Preprotein translocase SecY subunit signature 27 45 2.7E-96 T 14-10-2018 TSH58p_15265 392e615906d4de4ce30a744ff3c2f95a 446 PRINTS PR00303 Preprotein translocase SecY subunit signature 277 296 2.7E-96 T 14-10-2018 TSH58p_15265 392e615906d4de4ce30a744ff3c2f95a 446 PRINTS PR00303 Preprotein translocase SecY subunit signature 319 341 2.7E-96 T 14-10-2018 TSH58p_15265 392e615906d4de4ce30a744ff3c2f95a 446 PRINTS PR00303 Preprotein translocase SecY subunit signature 159 184 2.7E-96 T 14-10-2018 TSH58p_15265 392e615906d4de4ce30a744ff3c2f95a 446 PRINTS PR00303 Preprotein translocase SecY subunit signature 374 392 2.7E-96 T 14-10-2018 TSH58p_15265 392e615906d4de4ce30a744ff3c2f95a 446 PRINTS PR00303 Preprotein translocase SecY subunit signature 79 99 2.7E-96 T 14-10-2018 TSH58p_16295 360d9575af3157fbafc90acc0e769f5f 159 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 24 125 1.8E-29 T 14-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 TSH58p_16295 360d9575af3157fbafc90acc0e769f5f 159 TIGRFAM TIGR02799 thio_ybgC: tol-pal system-associated acyl-CoA thioesterase 20 147 2.7E-43 T 14-10-2018 IPR014166 Tol-Pal system-associated acyl-CoA thioesterase GO:0016790 TSH58p_16295 360d9575af3157fbafc90acc0e769f5f 159 Gene3D G3DSA:3.10.129.10 13 157 7.8E-38 T 14-10-2018 TSH58p_16295 360d9575af3157fbafc90acc0e769f5f 159 PIRSF PIRSF003230 12 156 3.0E-41 T 14-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 TSH58p_16295 360d9575af3157fbafc90acc0e769f5f 159 Pfam PF03061 Thioesterase superfamily 34 118 1.9E-17 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TSH58p_16295 360d9575af3157fbafc90acc0e769f5f 159 SUPERFAMILY SSF54637 18 150 4.27E-36 T 14-10-2018 IPR029069 HotDog domain superfamily TSH58p_00820 65425e57aed6a4e08b4f7ed91592154f 143 SUPERFAMILY SSF52172 23 141 1.71E-30 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_00820 65425e57aed6a4e08b4f7ed91592154f 143 Gene3D G3DSA:3.40.50.2300 21 143 9.9E-33 T 14-10-2018 TSH58p_00820 65425e57aed6a4e08b4f7ed91592154f 143 SMART SM00448 24 136 3.6E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_00820 65425e57aed6a4e08b4f7ed91592154f 143 Pfam PF00072 Response regulator receiver domain 26 136 4.3E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_25640 2ca772a8fb719812ab486bbf77226c49 374 Gene3D G3DSA:3.40.50.2300 90 337 1.0E-62 T 14-10-2018 TSH58p_25640 2ca772a8fb719812ab486bbf77226c49 374 Pfam PF13377 Periplasmic binding protein-like domain 199 360 1.8E-35 T 14-10-2018 TSH58p_25640 2ca772a8fb719812ab486bbf77226c49 374 SUPERFAMILY SSF53822 85 353 1.11E-56 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_25640 2ca772a8fb719812ab486bbf77226c49 374 ProSitePatterns PS00356 LacI-type HTH domain signature. 31 49 - T 14-10-2018 TSH58p_25640 2ca772a8fb719812ab486bbf77226c49 374 Gene3D G3DSA:3.40.50.2300 187 321 1.0E-62 T 14-10-2018 TSH58p_25640 2ca772a8fb719812ab486bbf77226c49 374 Pfam PF00356 Bacterial regulatory proteins, lacI family 30 75 2.3E-16 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TSH58p_25640 2ca772a8fb719812ab486bbf77226c49 374 SMART SM00354 28 98 3.3E-28 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TSH58p_25640 2ca772a8fb719812ab486bbf77226c49 374 SUPERFAMILY SSF47413 27 86 5.63E-16 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_25640 2ca772a8fb719812ab486bbf77226c49 374 Gene3D G3DSA:1.10.260.40 20 85 3.8E-19 T 14-10-2018 TSH58p_30015 94a47bf76c20bb611fbc6c02420c857a 631 Gene3D G3DSA:3.40.50.10810 137 325 7.3E-18 T 14-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily TSH58p_30015 94a47bf76c20bb611fbc6c02420c857a 631 Gene3D G3DSA:3.40.50.300 333 596 8.5E-31 T 14-10-2018 TSH58p_30015 94a47bf76c20bb611fbc6c02420c857a 631 SUPERFAMILY SSF52540 231 594 3.77E-29 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_30015 94a47bf76c20bb611fbc6c02420c857a 631 Pfam PF00176 SNF2 family N-terminal domain 143 372 2.1E-17 T 14-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 TSH58p_30015 94a47bf76c20bb611fbc6c02420c857a 631 SUPERFAMILY SSF52540 113 291 2.45E-22 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_30015 94a47bf76c20bb611fbc6c02420c857a 631 Pfam PF00271 Helicase conserved C-terminal domain 444 552 1.5E-4 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_30015 94a47bf76c20bb611fbc6c02420c857a 631 SMART SM00487 115 301 0.003 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSH58p_29720 3dfb41184f55a2deaf1e5f1893be1311 494 SUPERFAMILY SSF48452 10 155 2.06E-23 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29720 3dfb41184f55a2deaf1e5f1893be1311 494 Gene3D G3DSA:1.25.40.10 153 284 2.7E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29720 3dfb41184f55a2deaf1e5f1893be1311 494 SUPERFAMILY SSF48452 151 283 2.33E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29720 3dfb41184f55a2deaf1e5f1893be1311 494 SMART SM00028 38 71 160.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29720 3dfb41184f55a2deaf1e5f1893be1311 494 SMART SM00028 215 248 10.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29720 3dfb41184f55a2deaf1e5f1893be1311 494 SMART SM00028 72 105 0.0046 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29720 3dfb41184f55a2deaf1e5f1893be1311 494 SMART SM00028 4 37 47.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29720 3dfb41184f55a2deaf1e5f1893be1311 494 SMART SM00028 181 214 29.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29720 3dfb41184f55a2deaf1e5f1893be1311 494 SMART SM00028 106 139 0.15 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29720 3dfb41184f55a2deaf1e5f1893be1311 494 Pfam PF13432 Tetratricopeptide repeat 17 71 2.9E-4 T 14-10-2018 TSH58p_29720 3dfb41184f55a2deaf1e5f1893be1311 494 Pfam PF13432 Tetratricopeptide repeat 79 137 3.0E-8 T 14-10-2018 TSH58p_29720 3dfb41184f55a2deaf1e5f1893be1311 494 Pfam PF13432 Tetratricopeptide repeat 221 278 0.003 T 14-10-2018 TSH58p_29720 3dfb41184f55a2deaf1e5f1893be1311 494 Gene3D G3DSA:1.25.40.10 6 152 1.2E-26 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_32020 814b11d369742d17b82df45db72a81aa 150 SUPERFAMILY SSF46626 26 148 2.19E-20 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_32020 814b11d369742d17b82df45db72a81aa 150 Gene3D G3DSA:1.10.760.10 1 150 5.2E-40 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_32020 814b11d369742d17b82df45db72a81aa 150 Pfam PF00034 Cytochrome c 50 134 2.9E-8 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_06525 65c1ab501507a3b35bd7ce1994dca61e 408 Pfam PF00155 Aminotransferase class I and II 57 399 6.6E-37 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSH58p_06525 65c1ab501507a3b35bd7ce1994dca61e 408 Gene3D G3DSA:3.90.1150.10 21 401 6.4E-139 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_06525 65c1ab501507a3b35bd7ce1994dca61e 408 SUPERFAMILY SSF53383 4 404 1.99E-106 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_06525 65c1ab501507a3b35bd7ce1994dca61e 408 Gene3D G3DSA:3.40.640.10 74 297 6.4E-139 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_13190 d3cab03eca0815598f10d6a59bf45795 125 Gene3D G3DSA:3.30.720.120 1 54 2.4E-25 T 14-10-2018 TSH58p_13190 d3cab03eca0815598f10d6a59bf45795 125 SUPERFAMILY SSF54593 7 124 1.79E-23 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSH58p_13190 d3cab03eca0815598f10d6a59bf45795 125 PIRSF PIRSF039020 1 124 2.2E-47 T 14-10-2018 IPR026275 Glyoxalase/dioxygenase/EhpR TSH58p_13190 d3cab03eca0815598f10d6a59bf45795 125 Gene3D G3DSA:3.30.720.110 68 122 4.6E-28 T 14-10-2018 TSH58p_13190 d3cab03eca0815598f10d6a59bf45795 125 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 117 9.7E-9 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TSH58p_06150 dd744ac7d3238f4695ea00b9d7599d92 118 Pfam PF03640 Secreted repeat of unknown function 74 116 1.3E-20 T 14-10-2018 IPR005297 Lipoprotein repeat TSH58p_06150 dd744ac7d3238f4695ea00b9d7599d92 118 Pfam PF03640 Secreted repeat of unknown function 20 62 3.3E-15 T 14-10-2018 IPR005297 Lipoprotein repeat TSH58p_06150 dd744ac7d3238f4695ea00b9d7599d92 118 PIRSF PIRSF029720 2 118 1.9E-52 T 14-10-2018 IPR014558 Uncharacterised conserved lipoprotein TSH58p_23950 13089f7c84313622265336df01ef6f6d 321 Gene3D G3DSA:1.10.8.300 204 318 2.4E-27 T 14-10-2018 TSH58p_23950 13089f7c84313622265336df01ef6f6d 321 Gene3D G3DSA:3.40.50.300 22 191 5.3E-42 T 14-10-2018 TSH58p_23950 13089f7c84313622265336df01ef6f6d 321 PIRSF PIRSF002849 1 320 1.2E-113 T 14-10-2018 TSH58p_23950 13089f7c84313622265336df01ef6f6d 321 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 41 174 6.8E-59 T 14-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 TSH58p_23950 13089f7c84313622265336df01ef6f6d 321 SUPERFAMILY SSF52540 13 297 1.09E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_06585 b4d928691b9091cb1f33e25b3dae0096 322 Pfam PF04392 ABC transporter substrate binding protein 28 319 4.0E-107 T 14-10-2018 IPR007487 ABC transporter, substrate-binding protein TSH58p_06585 b4d928691b9091cb1f33e25b3dae0096 322 Gene3D G3DSA:3.40.50.2300 45 291 1.6E-100 T 14-10-2018 TSH58p_06585 b4d928691b9091cb1f33e25b3dae0096 322 SUPERFAMILY SSF53822 35 287 3.98E-25 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_06585 b4d928691b9091cb1f33e25b3dae0096 322 Gene3D G3DSA:3.40.50.2300 142 313 1.6E-100 T 14-10-2018 TSH58p_12070 b2ffdfb509499035710c7a897f70153a 178 TIGRFAM TIGR00385 dsbE: periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily 7 171 1.6E-53 T 14-10-2018 IPR004799 Periplasmic protein thiol:disulphide oxidoreductase DsbE GO:0015036|GO:0017004|GO:0030288 TSH58p_12070 b2ffdfb509499035710c7a897f70153a 178 Gene3D G3DSA:3.40.30.10 23 177 1.7E-41 T 14-10-2018 TSH58p_12070 b2ffdfb509499035710c7a897f70153a 178 Pfam PF08534 Redoxin 38 163 5.1E-14 T 14-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 TSH58p_12070 b2ffdfb509499035710c7a897f70153a 178 SUPERFAMILY SSF52833 32 171 2.67E-35 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_05985 4b45c50e4e5b29b23ddb18000460717b 469 Gene3D G3DSA:3.10.20.70 4 105 1.1E-36 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TSH58p_05985 4b45c50e4e5b29b23ddb18000460717b 469 SMART SM01230 103 379 1.3E-150 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TSH58p_05985 4b45c50e4e5b29b23ddb18000460717b 469 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 259 274 - T 14-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TSH58p_05985 4b45c50e4e5b29b23ddb18000460717b 469 ProSitePatterns PS00180 Glutamine synthetase signature 1. 51 69 - T 14-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TSH58p_05985 4b45c50e4e5b29b23ddb18000460717b 469 SUPERFAMILY SSF55931 104 468 2.06E-138 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TSH58p_05985 4b45c50e4e5b29b23ddb18000460717b 469 SUPERFAMILY SSF54368 5 102 2.88E-35 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TSH58p_05985 4b45c50e4e5b29b23ddb18000460717b 469 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 15 96 1.1E-30 T 14-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TSH58p_05985 4b45c50e4e5b29b23ddb18000460717b 469 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 386 398 - T 14-10-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TSH58p_05985 4b45c50e4e5b29b23ddb18000460717b 469 Gene3D G3DSA:3.30.590.10 106 455 2.4E-144 T 14-10-2018 TSH58p_05985 4b45c50e4e5b29b23ddb18000460717b 469 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 6 468 7.2E-205 T 14-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TSH58p_05985 4b45c50e4e5b29b23ddb18000460717b 469 Pfam PF00120 Glutamine synthetase, catalytic domain 104 466 1.5E-141 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TSH58p_23665 798c32b9f59732913bd8777872b32ed3 108 Pfam PF12680 SnoaL-like domain 10 104 6.8E-11 T 14-10-2018 IPR037401 SnoaL-like domain TSH58p_23665 798c32b9f59732913bd8777872b32ed3 108 SUPERFAMILY SSF54427 6 104 4.09E-14 T 14-10-2018 IPR032710 NTF2-like domain superfamily TSH58p_23665 798c32b9f59732913bd8777872b32ed3 108 Gene3D G3DSA:3.10.450.50 2 107 1.4E-28 T 14-10-2018 TSH58p_29575 f198e8e422c05a303f92b29ff8712766 410 Pfam PF10503 Esterase PHB depolymerase 140 332 1.1E-68 T 14-10-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 TSH58p_29575 f198e8e422c05a303f92b29ff8712766 410 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 142 325 1.1E-42 T 14-10-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 TSH58p_29575 f198e8e422c05a303f92b29ff8712766 410 Gene3D G3DSA:3.40.50.1820 122 402 1.3E-61 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_29575 f198e8e422c05a303f92b29ff8712766 410 SUPERFAMILY SSF53474 135 399 3.63E-39 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_04650 123fb70262b087267850f9a68416d9cf 448 Pfam PF11563 Protoglobin 8 160 3.0E-39 T 14-10-2018 TSH58p_04650 123fb70262b087267850f9a68416d9cf 448 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 250 412 3.1E-32 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_04650 123fb70262b087267850f9a68416d9cf 448 Gene3D G3DSA:1.10.490.10 1 155 6.0E-44 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 TSH58p_04650 123fb70262b087267850f9a68416d9cf 448 SMART SM00283 188 442 2.7E-48 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_04650 123fb70262b087267850f9a68416d9cf 448 Gene3D G3DSA:1.10.287.950 161 445 4.5E-56 T 14-10-2018 TSH58p_04650 123fb70262b087267850f9a68416d9cf 448 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 363 392 3.3E-24 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_04650 123fb70262b087267850f9a68416d9cf 448 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 209 238 3.3E-24 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_04650 123fb70262b087267850f9a68416d9cf 448 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 286 313 3.3E-24 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_04650 123fb70262b087267850f9a68416d9cf 448 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 315 344 3.3E-24 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_04650 123fb70262b087267850f9a68416d9cf 448 SUPERFAMILY SSF46458 10 155 6.98E-36 T 14-10-2018 IPR009050 Globin-like superfamily TSH58p_04650 123fb70262b087267850f9a68416d9cf 448 SUPERFAMILY SSF58104 167 441 1.01E-65 T 14-10-2018 TSH58p_07400 2e2bc541d18bc63238edb1bd203ac4fe 422 SUPERFAMILY SSF55174 315 420 4.71E-14 T 14-10-2018 TSH58p_07400 2e2bc541d18bc63238edb1bd203ac4fe 422 Gene3D G3DSA:1.10.240.10 234 332 2.5E-30 T 14-10-2018 TSH58p_07400 2e2bc541d18bc63238edb1bd203ac4fe 422 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 7 420 1.4E-108 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TSH58p_07400 2e2bc541d18bc63238edb1bd203ac4fe 422 Pfam PF00579 tRNA synthetases class I (W and Y) 33 332 7.5E-72 T 14-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_07400 2e2bc541d18bc63238edb1bd203ac4fe 422 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 6 421 42.754 T 14-10-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 TSH58p_07400 2e2bc541d18bc63238edb1bd203ac4fe 422 Gene3D G3DSA:3.40.50.620 1 233 5.5E-87 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_07400 2e2bc541d18bc63238edb1bd203ac4fe 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 173 188 1.9E-25 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TSH58p_07400 2e2bc541d18bc63238edb1bd203ac4fe 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 227 239 1.9E-25 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TSH58p_07400 2e2bc541d18bc63238edb1bd203ac4fe 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 48 70 1.9E-25 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TSH58p_07400 2e2bc541d18bc63238edb1bd203ac4fe 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 194 216 1.9E-25 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TSH58p_07400 2e2bc541d18bc63238edb1bd203ac4fe 422 Gene3D G3DSA:3.10.290.10 333 422 4.5E-19 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TSH58p_07400 2e2bc541d18bc63238edb1bd203ac4fe 422 SUPERFAMILY SSF52374 5 331 1.77E-97 T 14-10-2018 TSH58p_03375 d5e7ea0a8249286cd0356634481d141d 511 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 21 438 1.2E-142 T 14-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane TSH58p_29105 e183d7ca97ef7eb6eb3b7db0479ed4f0 264 Pfam PF00005 ABC transporter 32 181 1.4E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_29105 e183d7ca97ef7eb6eb3b7db0479ed4f0 264 Gene3D G3DSA:3.40.50.300 13 261 9.0E-61 T 14-10-2018 TSH58p_29105 e183d7ca97ef7eb6eb3b7db0479ed4f0 264 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_29105 e183d7ca97ef7eb6eb3b7db0479ed4f0 264 SMART SM00382 40 229 1.3E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_29105 e183d7ca97ef7eb6eb3b7db0479ed4f0 264 SUPERFAMILY SSF52540 15 250 1.81E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_11320 a41968e8daf54eb35c53356fce5c9d1a 84 SUPERFAMILY SSF64307 6 83 3.4E-16 T 14-10-2018 IPR036868 TusA-like domain superfamily TSH58p_11320 a41968e8daf54eb35c53356fce5c9d1a 84 Gene3D G3DSA:3.30.110.40 6 83 2.5E-15 T 14-10-2018 IPR036868 TusA-like domain superfamily TSH58p_11320 a41968e8daf54eb35c53356fce5c9d1a 84 Pfam PF01206 Sulfurtransferase TusA 11 83 4.8E-17 T 14-10-2018 IPR001455 TusA-like domain TSH58p_22210 10818935759ba96a8c56a0b5f6bbf5e4 110 Gene3D G3DSA:3.30.70.100 45 107 2.9E-18 T 14-10-2018 TSH58p_22210 10818935759ba96a8c56a0b5f6bbf5e4 110 SUPERFAMILY SSF55008 45 108 1.83E-17 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 TSH58p_22210 10818935759ba96a8c56a0b5f6bbf5e4 110 Pfam PF00403 Heavy-metal-associated domain 48 105 3.8E-14 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TSH58p_23595 7587dbaea8c9241535e383a2e623594e 275 Gene3D G3DSA:1.10.580.10 60 243 8.1E-32 T 14-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 TSH58p_23595 7587dbaea8c9241535e383a2e623594e 275 Pfam PF00285 Citrate synthase, C-terminal domain 8 58 6.6E-7 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 TSH58p_23595 7587dbaea8c9241535e383a2e623594e 275 Pfam PF00285 Citrate synthase, C-terminal domain 60 250 1.8E-32 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 TSH58p_23595 7587dbaea8c9241535e383a2e623594e 275 Gene3D G3DSA:1.10.230.10 109 217 8.1E-32 T 14-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain TSH58p_23595 7587dbaea8c9241535e383a2e623594e 275 SUPERFAMILY SSF48256 7 251 1.96E-55 T 14-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 TSH58p_23595 7587dbaea8c9241535e383a2e623594e 275 Gene3D G3DSA:1.10.580.10 14 59 2.4E-8 T 14-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 TSH58p_27550 4476ca3d54fbcd4698f864894ef810d5 544 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 368 531 2.1E-40 T 14-10-2018 IPR000160 GGDEF domain TSH58p_27550 4476ca3d54fbcd4698f864894ef810d5 544 Pfam PF02743 Cache domain 54 276 7.8E-22 T 14-10-2018 IPR033479 Double Cache domain 1 TSH58p_27550 4476ca3d54fbcd4698f864894ef810d5 544 SUPERFAMILY SSF103190 72 197 3.53E-5 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily TSH58p_27550 4476ca3d54fbcd4698f864894ef810d5 544 SMART SM00267 359 533 4.1E-54 T 14-10-2018 IPR000160 GGDEF domain TSH58p_27550 4476ca3d54fbcd4698f864894ef810d5 544 Gene3D G3DSA:3.30.70.270 369 536 1.0E-53 T 14-10-2018 TSH58p_27550 4476ca3d54fbcd4698f864894ef810d5 544 Pfam PF00990 Diguanylate cyclase, GGDEF domain 371 528 3.8E-45 T 14-10-2018 IPR000160 GGDEF domain TSH58p_27550 4476ca3d54fbcd4698f864894ef810d5 544 Gene3D G3DSA:3.30.450.20 46 189 2.8E-27 T 14-10-2018 TSH58p_27550 4476ca3d54fbcd4698f864894ef810d5 544 Gene3D G3DSA:3.30.450.20 193 280 4.0E-7 T 14-10-2018 TSH58p_27550 4476ca3d54fbcd4698f864894ef810d5 544 SUPERFAMILY SSF55073 375 534 1.08E-47 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_06045 9081fdab1afe3761018db61c4610be58 386 Gene3D G3DSA:3.20.20.20 109 385 1.8E-103 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSH58p_06045 9081fdab1afe3761018db61c4610be58 386 SUPERFAMILY SSF51717 118 381 4.84E-94 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSH58p_06045 9081fdab1afe3761018db61c4610be58 386 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 125 378 5.5E-93 T 14-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 TSH58p_06045 9081fdab1afe3761018db61c4610be58 386 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 159 172 - T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSH58p_06045 9081fdab1afe3761018db61c4610be58 386 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 125 140 - T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSH58p_06045 9081fdab1afe3761018db61c4610be58 386 Pfam PF00809 Pterin binding enzyme 126 365 1.3E-76 T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSH58p_28885 827080e9526789aebf441212f819ba43 434 Gene3D G3DSA:3.20.20.140 65 376 2.3E-126 T 14-10-2018 TSH58p_28885 827080e9526789aebf441212f819ba43 434 Hamap MF_00220_B Dihydroorotase [pyrC]. 8 432 38.902 T 14-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSH58p_28885 827080e9526789aebf441212f819ba43 434 SUPERFAMILY SSF51556 64 373 3.69E-99 T 14-10-2018 IPR032466 Metal-dependent hydrolase TSH58p_28885 827080e9526789aebf441212f819ba43 434 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 25 430 3.4E-108 T 14-10-2018 TSH58p_28885 827080e9526789aebf441212f819ba43 434 Gene3D G3DSA:2.30.40.10 14 429 2.3E-126 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_28885 827080e9526789aebf441212f819ba43 434 SUPERFAMILY SSF51338 9 431 3.92E-23 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_28885 827080e9526789aebf441212f819ba43 434 Pfam PF01979 Amidohydrolase family 62 429 3.3E-22 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TSH58p_15240 1f3666046c376a9ab2d177706bc27bd7 177 SUPERFAMILY SSF56053 1 82 6.54E-25 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15240 1f3666046c376a9ab2d177706bc27bd7 177 Gene3D G3DSA:3.90.930.12 1 82 6.9E-28 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15240 1f3666046c376a9ab2d177706bc27bd7 177 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 2.0E-73 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TSH58p_15240 1f3666046c376a9ab2d177706bc27bd7 177 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 14-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15240 1f3666046c376a9ab2d177706bc27bd7 177 Gene3D G3DSA:3.90.930.12 83 177 1.6E-39 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15240 1f3666046c376a9ab2d177706bc27bd7 177 PRINTS PR00059 Ribosomal protein L6 signature 99 115 6.7E-32 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TSH58p_15240 1f3666046c376a9ab2d177706bc27bd7 177 PRINTS PR00059 Ribosomal protein L6 signature 71 96 6.7E-32 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TSH58p_15240 1f3666046c376a9ab2d177706bc27bd7 177 PRINTS PR00059 Ribosomal protein L6 signature 141 162 6.7E-32 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TSH58p_15240 1f3666046c376a9ab2d177706bc27bd7 177 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 35.92 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TSH58p_15240 1f3666046c376a9ab2d177706bc27bd7 177 Pfam PF00347 Ribosomal protein L6 91 164 3.1E-21 T 14-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15240 1f3666046c376a9ab2d177706bc27bd7 177 Pfam PF00347 Ribosomal protein L6 11 82 1.6E-18 T 14-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15240 1f3666046c376a9ab2d177706bc27bd7 177 SUPERFAMILY SSF56053 83 177 1.83E-36 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15240 1f3666046c376a9ab2d177706bc27bd7 177 PIRSF PIRSF002162 1 177 8.3E-49 T 14-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_13010 34fe60ec9941af152fe6ab0ff1450a18 325 Gene3D G3DSA:3.40.50.720 7 295 2.5E-108 T 14-10-2018 TSH58p_13010 34fe60ec9941af152fe6ab0ff1450a18 325 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 238 1.0E-77 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TSH58p_13010 34fe60ec9941af152fe6ab0ff1450a18 325 Gene3D G3DSA:3.90.25.10 169 304 2.5E-108 T 14-10-2018 TSH58p_13010 34fe60ec9941af152fe6ab0ff1450a18 325 SUPERFAMILY SSF51735 2 308 1.59E-77 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_13010 34fe60ec9941af152fe6ab0ff1450a18 325 Hamap MF_00956 GDP-L-fucose synthase [fcl]. 4 306 49.181 T 14-10-2018 IPR028614 GDP-L-fucose synthase/GDP-L-colitose synthase GO:0009226|GO:0016491 KEGG: 00051+1.1.1.271|KEGG: 00520+1.1.1.271|MetaCyc: PWY-66|Reactome: R-HSA-6787639 TSH58p_18125 ec55e71bd6d5306381e85117b838b355 1112 Gene3D G3DSA:2.60.120.260 155 237 5.2E-5 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily TSH58p_18125 ec55e71bd6d5306381e85117b838b355 1112 Gene3D G3DSA:2.160.20.10 486 820 1.6E-23 T 14-10-2018 IPR012334 Pectin lyase fold TSH58p_18125 ec55e71bd6d5306381e85117b838b355 1112 SUPERFAMILY SSF51120 960 1080 6.02E-21 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_18125 ec55e71bd6d5306381e85117b838b355 1112 Gene3D G3DSA:2.60.60.40 10 128 1.4E-6 T 14-10-2018 TSH58p_18125 ec55e71bd6d5306381e85117b838b355 1112 SMART SM00710 652 679 480.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_18125 ec55e71bd6d5306381e85117b838b355 1112 SMART SM00710 623 645 5.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_18125 ec55e71bd6d5306381e85117b838b355 1112 SMART SM00710 571 593 240.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_18125 ec55e71bd6d5306381e85117b838b355 1112 SMART SM00710 684 721 21.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_18125 ec55e71bd6d5306381e85117b838b355 1112 SMART SM00710 723 745 1500.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_18125 ec55e71bd6d5306381e85117b838b355 1112 SMART SM00710 523 545 290.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_18125 ec55e71bd6d5306381e85117b838b355 1112 SMART SM00710 595 622 350.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_18125 ec55e71bd6d5306381e85117b838b355 1112 SMART SM00710 548 569 150.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_18125 ec55e71bd6d5306381e85117b838b355 1112 Pfam PF16841 Ca-dependent carbohydrate-binding module xylan-binding 13 103 1.3E-29 T 14-10-2018 IPR031768 Carbohydrate binding module, xylan-binding domain MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSH58p_18125 ec55e71bd6d5306381e85117b838b355 1112 Pfam PF16841 Ca-dependent carbohydrate-binding module xylan-binding 155 238 2.2E-12 T 14-10-2018 IPR031768 Carbohydrate binding module, xylan-binding domain MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSH58p_18125 ec55e71bd6d5306381e85117b838b355 1112 Gene3D G3DSA:2.160.20.10 253 387 5.1E-16 T 14-10-2018 IPR012334 Pectin lyase fold TSH58p_18125 ec55e71bd6d5306381e85117b838b355 1112 PRINTS PR00313 NodO calcium binding signature 1003 1011 3.8E-6 T 14-10-2018 TSH58p_18125 ec55e71bd6d5306381e85117b838b355 1112 PRINTS PR00313 NodO calcium binding signature 1012 1021 3.8E-6 T 14-10-2018 TSH58p_18125 ec55e71bd6d5306381e85117b838b355 1112 PRINTS PR00313 NodO calcium binding signature 994 1002 3.8E-6 T 14-10-2018 TSH58p_18125 ec55e71bd6d5306381e85117b838b355 1112 PRINTS PR00313 NodO calcium binding signature 973 984 3.8E-6 T 14-10-2018 TSH58p_18125 ec55e71bd6d5306381e85117b838b355 1112 SUPERFAMILY SSF51126 261 855 3.05E-31 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor TSH58p_18125 ec55e71bd6d5306381e85117b838b355 1112 Pfam PF13229 Right handed beta helix region 520 692 1.6E-12 T 14-10-2018 IPR039448 Right handed beta helix domain TSH58p_18125 ec55e71bd6d5306381e85117b838b355 1112 Gene3D G3DSA:2.150.10.10 964 1101 1.1E-14 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_10145 6e23ed9aabb17a11dbfe8e8f4105b4eb 171 Pfam PF12802 MarR family 48 105 1.5E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_10145 6e23ed9aabb17a11dbfe8e8f4105b4eb 171 Gene3D G3DSA:1.10.10.10 7 158 9.0E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_10145 6e23ed9aabb17a11dbfe8e8f4105b4eb 171 SMART SM00347 42 142 1.5E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_10145 6e23ed9aabb17a11dbfe8e8f4105b4eb 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 102 118 8.5E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_10145 6e23ed9aabb17a11dbfe8e8f4105b4eb 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 132 152 8.5E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_10145 6e23ed9aabb17a11dbfe8e8f4105b4eb 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 98 8.5E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_10145 6e23ed9aabb17a11dbfe8e8f4105b4eb 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 82 8.5E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_10145 6e23ed9aabb17a11dbfe8e8f4105b4eb 171 SUPERFAMILY SSF46785 16 158 3.24E-28 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_08065 bb8ea99810c363f6b67b4b2a60e177a4 477 Gene3D G3DSA:2.160.20.80 169 284 8.2E-28 T 14-10-2018 TSH58p_08065 bb8ea99810c363f6b67b4b2a60e177a4 477 Gene3D G3DSA:2.160.20.80 66 156 3.5E-20 T 14-10-2018 TSH58p_08065 bb8ea99810c363f6b67b4b2a60e177a4 477 Pfam PF00805 Pentapeptide repeats (8 copies) 341 380 2.8E-12 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_08065 bb8ea99810c363f6b67b4b2a60e177a4 477 Pfam PF00805 Pentapeptide repeats (8 copies) 173 197 0.0011 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_08065 bb8ea99810c363f6b67b4b2a60e177a4 477 Pfam PF00805 Pentapeptide repeats (8 copies) 73 106 0.0016 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_08065 bb8ea99810c363f6b67b4b2a60e177a4 477 Pfam PF00805 Pentapeptide repeats (8 copies) 305 340 1.5E-6 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_08065 bb8ea99810c363f6b67b4b2a60e177a4 477 Pfam PF00805 Pentapeptide repeats (8 copies) 109 148 2.9E-12 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_08065 bb8ea99810c363f6b67b4b2a60e177a4 477 Pfam PF00805 Pentapeptide repeats (8 copies) 402 441 2.9E-11 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_08065 bb8ea99810c363f6b67b4b2a60e177a4 477 Pfam PF00805 Pentapeptide repeats (8 copies) 242 272 5.4E-6 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_08065 bb8ea99810c363f6b67b4b2a60e177a4 477 Pfam PF00805 Pentapeptide repeats (8 copies) 203 241 6.0E-10 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_08065 bb8ea99810c363f6b67b4b2a60e177a4 477 SUPERFAMILY SSF141571 172 273 2.75E-26 T 14-10-2018 TSH58p_08065 bb8ea99810c363f6b67b4b2a60e177a4 477 SUPERFAMILY SSF141571 72 152 4.45E-20 T 14-10-2018 TSH58p_08065 bb8ea99810c363f6b67b4b2a60e177a4 477 SUPERFAMILY SSF141571 305 458 3.83E-32 T 14-10-2018 TSH58p_08065 bb8ea99810c363f6b67b4b2a60e177a4 477 Gene3D G3DSA:2.160.20.80 303 462 4.9E-39 T 14-10-2018 TSH58p_09565 0fc73289ae1424d010aef7f0cc282439 134 SUPERFAMILY SSF52172 2 121 5.27E-41 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_09565 0fc73289ae1424d010aef7f0cc282439 134 Pfam PF00072 Response regulator receiver domain 5 116 6.8E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_09565 0fc73289ae1424d010aef7f0cc282439 134 Gene3D G3DSA:3.40.50.12740 1 132 1.6E-45 T 14-10-2018 TSH58p_09565 0fc73289ae1424d010aef7f0cc282439 134 SMART SM00448 3 116 2.8E-42 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_18590 5386640ed326411caa639c153c3d6f3a 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 9.4E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_18590 5386640ed326411caa639c153c3d6f3a 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 9.4E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_18590 5386640ed326411caa639c153c3d6f3a 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 9.4E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_18590 5386640ed326411caa639c153c3d6f3a 304 Gene3D G3DSA:3.40.190.10 161 256 5.5E-57 T 14-10-2018 TSH58p_18590 5386640ed326411caa639c153c3d6f3a 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 9.1E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_18590 5386640ed326411caa639c153c3d6f3a 304 SUPERFAMILY SSF53850 94 289 1.86E-35 T 14-10-2018 TSH58p_18590 5386640ed326411caa639c153c3d6f3a 304 Gene3D G3DSA:3.40.190.10 102 283 5.5E-57 T 14-10-2018 TSH58p_18590 5386640ed326411caa639c153c3d6f3a 304 SUPERFAMILY SSF46785 2 84 2.8E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_18590 5386640ed326411caa639c153c3d6f3a 304 Gene3D G3DSA:1.10.10.10 6 92 2.0E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_18590 5386640ed326411caa639c153c3d6f3a 304 Pfam PF03466 LysR substrate binding domain 94 286 5.3E-36 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_30205 07219b9f81be398f0dca8294e976f08e 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 6.5E-15 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_30205 07219b9f81be398f0dca8294e976f08e 198 Gene3D G3DSA:1.10.357.10 52 190 4.2E-36 T 14-10-2018 TSH58p_30205 07219b9f81be398f0dca8294e976f08e 198 SUPERFAMILY SSF48498 78 190 1.65E-23 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TSH58p_30205 07219b9f81be398f0dca8294e976f08e 198 SUPERFAMILY SSF46689 4 73 3.95E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_30205 07219b9f81be398f0dca8294e976f08e 198 Gene3D G3DSA:1.10.10.60 4 51 9.1E-21 T 14-10-2018 TSH58p_30205 07219b9f81be398f0dca8294e976f08e 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 2.2E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_30205 07219b9f81be398f0dca8294e976f08e 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.2E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_25660 e8a29a08dc251f088311ce2b92d40a74 169 Pfam PF09349 OHCU decarboxylase 5 165 1.2E-45 T 14-10-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 TSH58p_25660 e8a29a08dc251f088311ce2b92d40a74 169 Gene3D G3DSA:1.10.3330.10 5 169 4.7E-65 T 14-10-2018 IPR036778 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase superfamily KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 TSH58p_25660 e8a29a08dc251f088311ce2b92d40a74 169 SUPERFAMILY SSF158694 5 168 9.03E-55 T 14-10-2018 IPR036778 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase superfamily KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 TSH58p_25660 e8a29a08dc251f088311ce2b92d40a74 169 TIGRFAM TIGR03164 UHCUDC: OHCU decarboxylase 6 167 1.0E-67 T 14-10-2018 IPR017580 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 1 GO:0019428 KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 TSH58p_14120 69e3e9a6c506e6ce05af8bafdef595a8 160 Gene3D G3DSA:3.40.1350.10 13 156 7.4E-59 T 14-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 TSH58p_14120 69e3e9a6c506e6ce05af8bafdef595a8 160 Pfam PF06319 DNA repair protein MmcB-like 18 151 2.7E-57 T 14-10-2018 IPR009394 DNA repair protein MmcB-like TSH58p_14120 69e3e9a6c506e6ce05af8bafdef595a8 160 PIRSF PIRSF031796 9 158 1.1E-52 T 14-10-2018 IPR009394 DNA repair protein MmcB-like TSH58p_06635 60173b8c9a5ff196cd993a3bad3d9e73 67 Pfam PF01165 Ribosomal protein S21 2 55 3.7E-20 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_06635 60173b8c9a5ff196cd993a3bad3d9e73 67 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 1 56 7.5E-21 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_06635 60173b8c9a5ff196cd993a3bad3d9e73 67 Gene3D G3DSA:1.20.5.1150 14 52 5.6E-9 T 14-10-2018 IPR038380 Ribosomal protein S21 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_06635 60173b8c9a5ff196cd993a3bad3d9e73 67 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 13 40 2.0E-7 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_06635 60173b8c9a5ff196cd993a3bad3d9e73 67 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 10 55 13.58 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_06635 60173b8c9a5ff196cd993a3bad3d9e73 67 ProSitePatterns PS01181 Ribosomal protein S21 signature. 11 23 - T 14-10-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_06635 60173b8c9a5ff196cd993a3bad3d9e73 67 PRINTS PR00976 Ribosomal protein S21 family signature 35 45 7.3E-5 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_06635 60173b8c9a5ff196cd993a3bad3d9e73 67 PRINTS PR00976 Ribosomal protein S21 family signature 23 33 7.3E-5 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_06635 60173b8c9a5ff196cd993a3bad3d9e73 67 PRINTS PR00976 Ribosomal protein S21 family signature 11 20 7.3E-5 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_09890 1b340fdc835696bafb63076152f33fe3 543 Gene3D G3DSA:2.70.98.70 313 511 3.3E-8 T 14-10-2018 TSH58p_09890 1b340fdc835696bafb63076152f33fe3 543 Pfam PF07940 Heparinase II/III-like protein 296 528 1.7E-63 T 14-10-2018 IPR012480 Heparinase II/III-like GO:0016829 TSH58p_09890 1b340fdc835696bafb63076152f33fe3 543 Gene3D G3DSA:1.50.10.100 45 296 1.2E-34 T 14-10-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 TSH58p_09890 1b340fdc835696bafb63076152f33fe3 543 Pfam PF16889 Heparinase II/III N-terminus 118 288 1.6E-6 T 14-10-2018 IPR031680 Heparin-sulfate lyase, N-terminal MetaCyc: PWY-7651 TSH58p_19990 9240310e18153b4ca463fc407eb28187 502 Gene3D G3DSA:3.40.462.20 253 469 1.2E-100 T 14-10-2018 TSH58p_19990 9240310e18153b4ca463fc407eb28187 502 Pfam PF08031 Berberine and berberine like 456 500 1.7E-14 T 14-10-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 TSH58p_19990 9240310e18153b4ca463fc407eb28187 502 SUPERFAMILY SSF56176 42 250 3.92E-44 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TSH58p_19990 9240310e18153b4ca463fc407eb28187 502 Gene3D G3DSA:3.30.465.40 68 499 1.2E-100 T 14-10-2018 TSH58p_19990 9240310e18153b4ca463fc407eb28187 502 Pfam PF01565 FAD binding domain 81 214 1.9E-24 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TSH58p_24625 0d9e70f03c303c24914642fd6cb7374a 194 Pfam PF07883 Cupin domain 119 188 4.5E-18 T 14-10-2018 IPR013096 Cupin 2, conserved barrel TSH58p_24625 0d9e70f03c303c24914642fd6cb7374a 194 Gene3D G3DSA:2.60.120.10 89 193 4.9E-20 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_24625 0d9e70f03c303c24914642fd6cb7374a 194 SUPERFAMILY SSF47413 8 73 3.49E-15 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_24625 0d9e70f03c303c24914642fd6cb7374a 194 SUPERFAMILY SSF51182 53 192 9.4E-25 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_24625 0d9e70f03c303c24914642fd6cb7374a 194 SMART SM00530 13 68 2.2E-11 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_24625 0d9e70f03c303c24914642fd6cb7374a 194 Gene3D G3DSA:1.10.260.40 4 73 7.3E-16 T 14-10-2018 TSH58p_24625 0d9e70f03c303c24914642fd6cb7374a 194 Pfam PF13560 Helix-turn-helix domain 11 60 4.8E-12 T 14-10-2018 TSH58p_17180 245ef2e55f9f69244e7e5662ff904df5 307 SUPERFAMILY SSF110581 2 301 2.35E-114 T 14-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 TSH58p_17180 245ef2e55f9f69244e7e5662ff904df5 307 Pfam PF04227 Indigoidine synthase A like protein 10 299 1.1E-130 T 14-10-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 TSH58p_17180 245ef2e55f9f69244e7e5662ff904df5 307 Hamap MF_01876 Pseudouridine-5'-phosphate glycosidase [psuG]. 9 303 44.723 T 14-10-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 TSH58p_17180 245ef2e55f9f69244e7e5662ff904df5 307 Gene3D G3DSA:3.40.1790.10 2 306 3.0E-133 T 14-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 TSH58p_09260 b9b785473040a9dbd1aee4f9bee7c549 794 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 363 523 1.9E-40 T 14-10-2018 IPR000160 GGDEF domain TSH58p_09260 b9b785473040a9dbd1aee4f9bee7c549 794 SMART SM00304 177 230 1.7E-6 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_09260 b9b785473040a9dbd1aee4f9bee7c549 794 Gene3D G3DSA:3.30.450.20 231 356 8.2E-16 T 14-10-2018 TSH58p_09260 b9b785473040a9dbd1aee4f9bee7c549 794 Gene3D G3DSA:1.10.8.500 178 228 2.0E-12 T 14-10-2018 TSH58p_09260 b9b785473040a9dbd1aee4f9bee7c549 794 SMART SM00267 354 526 2.0E-63 T 14-10-2018 IPR000160 GGDEF domain TSH58p_09260 b9b785473040a9dbd1aee4f9bee7c549 794 Gene3D G3DSA:3.20.20.450 537 789 4.6E-100 T 14-10-2018 IPR035919 EAL domain superfamily TSH58p_09260 b9b785473040a9dbd1aee4f9bee7c549 794 Pfam PF00990 Diguanylate cyclase, GGDEF domain 365 521 5.4E-46 T 14-10-2018 IPR000160 GGDEF domain TSH58p_09260 b9b785473040a9dbd1aee4f9bee7c549 794 SUPERFAMILY SSF55785 244 361 6.6E-14 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_09260 b9b785473040a9dbd1aee4f9bee7c549 794 SMART SM00052 536 781 1.7E-116 T 14-10-2018 IPR001633 EAL domain TSH58p_09260 b9b785473040a9dbd1aee4f9bee7c549 794 Pfam PF08448 PAS fold 240 354 6.5E-8 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_09260 b9b785473040a9dbd1aee4f9bee7c549 794 Pfam PF00563 EAL domain 542 776 4.4E-72 T 14-10-2018 IPR001633 EAL domain TSH58p_09260 b9b785473040a9dbd1aee4f9bee7c549 794 SUPERFAMILY SSF141868 542 786 1.06E-86 T 14-10-2018 IPR035919 EAL domain superfamily TSH58p_09260 b9b785473040a9dbd1aee4f9bee7c549 794 SUPERFAMILY SSF158472 179 225 8.76E-8 T 14-10-2018 TSH58p_09260 b9b785473040a9dbd1aee4f9bee7c549 794 SUPERFAMILY SSF55073 370 528 2.59E-46 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_09260 b9b785473040a9dbd1aee4f9bee7c549 794 Gene3D G3DSA:3.30.70.270 359 533 2.0E-53 T 14-10-2018 TSH58p_09260 b9b785473040a9dbd1aee4f9bee7c549 794 SMART SM00091 233 299 3.5E-6 T 14-10-2018 IPR000014 PAS domain TSH58p_09260 b9b785473040a9dbd1aee4f9bee7c549 794 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 232 361 6.0E-12 T 14-10-2018 IPR000014 PAS domain TSH58p_06395 b99afbc86b7ba7de9abb7f47cf34e176 575 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 555 572 8.3E-5 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSH58p_06395 b99afbc86b7ba7de9abb7f47cf34e176 575 SMART SM00382 365 550 7.6E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_06395 b99afbc86b7ba7de9abb7f47cf34e176 575 Gene3D G3DSA:3.40.50.300 332 571 8.4E-54 T 14-10-2018 TSH58p_06395 b99afbc86b7ba7de9abb7f47cf34e176 575 Pfam PF00005 ABC transporter 357 501 1.2E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_06395 b99afbc86b7ba7de9abb7f47cf34e176 575 SUPERFAMILY SSF52540 339 571 6.86E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_06395 b99afbc86b7ba7de9abb7f47cf34e176 575 Pfam PF02653 Branched-chain amino acid transport system / permease component 40 297 8.9E-38 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_24605 eb729afcb9c12f1edc13763ba51e6228 369 Pfam PF00005 ABC transporter 29 171 1.3E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_24605 eb729afcb9c12f1edc13763ba51e6228 369 Pfam PF08402 TOBE domain 288 366 3.3E-16 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TSH58p_24605 eb729afcb9c12f1edc13763ba51e6228 369 SUPERFAMILY SSF52540 13 251 9.01E-86 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_24605 eb729afcb9c12f1edc13763ba51e6228 369 Gene3D G3DSA:3.40.50.300 5 248 9.0E-77 T 14-10-2018 TSH58p_24605 eb729afcb9c12f1edc13763ba51e6228 369 Gene3D G3DSA:2.40.50.100 291 358 2.8E-5 T 14-10-2018 TSH58p_24605 eb729afcb9c12f1edc13763ba51e6228 369 SMART SM00382 38 220 8.0E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_24605 eb729afcb9c12f1edc13763ba51e6228 369 SUPERFAMILY SSF50331 246 366 1.43E-18 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSH58p_24605 eb729afcb9c12f1edc13763ba51e6228 369 Gene3D G3DSA:2.40.50.140 249 290 2.8E-5 T 14-10-2018 TSH58p_24605 eb729afcb9c12f1edc13763ba51e6228 369 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_24605 eb729afcb9c12f1edc13763ba51e6228 369 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 44 364 2.7E-114 T 14-10-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 TSH58p_05175 f3dd012d943cfb47cc43a8c4357dd895 233 Pfam PF00571 CBS domain 90 144 1.4E-13 T 14-10-2018 IPR000644 CBS domain TSH58p_05175 f3dd012d943cfb47cc43a8c4357dd895 233 Pfam PF00571 CBS domain 4 56 6.2E-17 T 14-10-2018 IPR000644 CBS domain TSH58p_05175 f3dd012d943cfb47cc43a8c4357dd895 233 Gene3D G3DSA:3.10.580.10 1 149 1.0E-42 T 14-10-2018 TSH58p_05175 f3dd012d943cfb47cc43a8c4357dd895 233 SMART SM00116 10 58 1.2E-12 T 14-10-2018 IPR000644 CBS domain TSH58p_05175 f3dd012d943cfb47cc43a8c4357dd895 233 SMART SM00116 97 144 1.3E-10 T 14-10-2018 IPR000644 CBS domain TSH58p_05175 f3dd012d943cfb47cc43a8c4357dd895 233 SUPERFAMILY SSF54631 1 149 9.98E-40 T 14-10-2018 TSH58p_05175 f3dd012d943cfb47cc43a8c4357dd895 233 Pfam PF04972 BON domain 156 223 9.8E-13 T 14-10-2018 IPR007055 BON domain TSH58p_05175 f3dd012d943cfb47cc43a8c4357dd895 233 PIRSF PIRSF036990 1 232 1.1E-82 T 14-10-2018 IPR017080 Uncharacterised conserved protein UCP036990, CBS, BON TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 SUPERFAMILY SSF51120 4246 4398 3.98E-25 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 SUPERFAMILY SSF69318 1945 2212 1.22E-31 T 14-10-2018 TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Gene3D G3DSA:2.150.10.10 4301 4353 1.9E-12 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Gene3D G3DSA:2.150.10.10 4354 4412 9.8E-13 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Gene3D G3DSA:2.150.10.10 4244 4300 3.5E-8 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Pfam PF13753 Putative flagellar system-associated repeat 887 965 1.3E-17 T 14-10-2018 IPR028059 Putative flagellar system-associated repeat TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Pfam PF13753 Putative flagellar system-associated repeat 389 467 1.6E-24 T 14-10-2018 IPR028059 Putative flagellar system-associated repeat TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Pfam PF13753 Putative flagellar system-associated repeat 1359 1438 6.0E-18 T 14-10-2018 IPR028059 Putative flagellar system-associated repeat TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Pfam PF13753 Putative flagellar system-associated repeat 779 857 9.7E-26 T 14-10-2018 IPR028059 Putative flagellar system-associated repeat TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Pfam PF13753 Putative flagellar system-associated repeat 1 70 6.6E-23 T 14-10-2018 IPR028059 Putative flagellar system-associated repeat TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Pfam PF13753 Putative flagellar system-associated repeat 1838 1916 1.9E-19 T 14-10-2018 IPR028059 Putative flagellar system-associated repeat TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 4428 4446 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 SUPERFAMILY SSF51120 4345 4525 3.66E-36 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Gene3D G3DSA:2.60.40.10 3267 3353 4.7E-13 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Gene3D G3DSA:2.60.40.10 2501 2588 9.5E-14 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Gene3D G3DSA:2.60.40.10 2405 2491 5.2E-13 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Gene3D G3DSA:2.60.40.10 3171 3257 5.1E-11 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Gene3D G3DSA:2.60.40.10 3458 3543 1.1E-11 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Gene3D G3DSA:2.60.40.10 3648 3735 2.5E-12 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Gene3D G3DSA:2.60.40.10 2312 2395 7.9E-13 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Gene3D G3DSA:2.60.40.10 2688 2783 2.3E-13 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Gene3D G3DSA:2.60.40.10 2975 3070 3.4E-12 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Gene3D G3DSA:2.60.40.10 3835 3934 3.2E-14 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Gene3D G3DSA:2.60.40.10 2784 2879 4.7E-13 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Gene3D G3DSA:2.60.40.10 2880 2974 1.2E-12 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Gene3D G3DSA:2.60.40.10 3071 3169 5.9E-13 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Gene3D G3DSA:2.60.40.10 3736 3834 4.7E-13 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Gene3D G3DSA:2.60.40.10 3355 3456 5.4E-13 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Gene3D G3DSA:2.60.40.10 3547 3646 1.4E-11 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Gene3D G3DSA:2.60.40.10 2590 2687 4.8E-13 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Gene3D G3DSA:2.60.40.10 2214 2311 6.8E-14 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Gene3D G3DSA:2.60.40.10 1743 1844 5.0E-13 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Gene3D G3DSA:2.60.40.10 1265 1364 1.8E-11 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 SUPERFAMILY SSF69318 1004 1262 6.02E-33 T 14-10-2018 TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 SUPERFAMILY SSF69318 1459 1737 7.06E-35 T 14-10-2018 TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Pfam PF12245 Bacterial Ig-like domain (group 3) 2766 2786 2.8 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Pfam PF12245 Bacterial Ig-like domain (group 3) 3914 3934 2.6 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Pfam PF12245 Bacterial Ig-like domain (group 3) 2957 2977 0.017 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Pfam PF12245 Bacterial Ig-like domain (group 3) 3341 3361 2.6 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 4446 4464 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Gene3D G3DSA:2.150.10.10 4413 4530 7.1E-23 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 1968 2034 2.4E-10 T 14-10-2018 TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 1549 1614 3.0E-10 T 14-10-2018 TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 2078 2144 7.2E-12 T 14-10-2018 TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 1659 1724 8.5E-10 T 14-10-2018 TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 1182 1247 8.5E-8 T 14-10-2018 TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 1017 1082 2.0E-9 T 14-10-2018 TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 PRINTS PR00313 NodO calcium binding signature 4459 4468 6.6E-10 T 14-10-2018 TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 PRINTS PR00313 NodO calcium binding signature 4357 4368 6.6E-10 T 14-10-2018 TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 PRINTS PR00313 NodO calcium binding signature 4414 4422 6.6E-10 T 14-10-2018 TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 PRINTS PR00313 NodO calcium binding signature 4441 4449 6.6E-10 T 14-10-2018 TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 4320 4338 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 TIGRFAM TIGR02059 swm_rep_I: cyanobacterial long protein repeat 1828 1917 5.3E-7 T 14-10-2018 IPR011801 Cyanobacterial long protein repeat TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 TIGRFAM TIGR02059 swm_rep_I: cyanobacterial long protein repeat 2 72 1.6E-17 T 14-10-2018 IPR011801 Cyanobacterial long protein repeat TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 TIGRFAM TIGR02059 swm_rep_I: cyanobacterial long protein repeat 381 469 1.7E-14 T 14-10-2018 IPR011801 Cyanobacterial long protein repeat TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 TIGRFAM TIGR02059 swm_rep_I: cyanobacterial long protein repeat 885 966 1.8E-7 T 14-10-2018 IPR011801 Cyanobacterial long protein repeat TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 TIGRFAM TIGR02059 swm_rep_I: cyanobacterial long protein repeat 1343 1439 1.8E-7 T 14-10-2018 IPR011801 Cyanobacterial long protein repeat TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 TIGRFAM TIGR02059 swm_rep_I: cyanobacterial long protein repeat 787 859 3.7E-17 T 14-10-2018 IPR011801 Cyanobacterial long protein repeat TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 4290 4303 0.15 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 4414 4430 0.019 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 4431 4448 0.0026 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 4341 4358 0.019 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 4377 4393 0.3 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 4450 4466 0.17 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 4306 4322 0.0027 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 4360 4376 0.0031 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 4324 4340 4.9 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 4271 4286 0.055 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_20090 8108fedb0d0b40456ec54320d2593bec 4534 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 4311 4329 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_10625 ab6d7b8a784572a5491289ed43621321 388 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 12 348 9.2E-86 T 14-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 TSH58p_10625 ab6d7b8a784572a5491289ed43621321 388 Gene3D G3DSA:3.80.30.20 1 307 1.2E-90 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TSH58p_10625 ab6d7b8a784572a5491289ed43621321 388 SUPERFAMILY SSF102114 6 387 4.58E-106 T 14-10-2018 TSH58p_10625 ab6d7b8a784572a5491289ed43621321 388 Pfam PF04055 Radical SAM superfamily 14 179 1.4E-17 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSH58p_10625 ab6d7b8a784572a5491289ed43621321 388 Pfam PF06969 HemN C-terminal domain 313 376 1.1E-11 T 14-10-2018 IPR010723 HemN, C-terminal TSH58p_10625 ab6d7b8a784572a5491289ed43621321 388 SMART SM00729 9 228 1.6E-43 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSH58p_29630 81bbb8c44dab1f0d38ca3dd16da9d08c 135 Pfam PF00011 Hsp20/alpha crystallin family 47 132 3.1E-8 T 14-10-2018 IPR002068 Alpha crystallin/Hsp20 domain TSH58p_29630 81bbb8c44dab1f0d38ca3dd16da9d08c 135 Gene3D G3DSA:2.60.40.790 5 134 9.6E-18 T 14-10-2018 IPR008978 HSP20-like chaperone TSH58p_29630 81bbb8c44dab1f0d38ca3dd16da9d08c 135 SUPERFAMILY SSF49764 26 133 2.62E-20 T 14-10-2018 IPR008978 HSP20-like chaperone TSH58p_05360 312916aa2e6483390f88331e2af9a1df 493 SUPERFAMILY SSF51905 6 267 4.4E-17 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_05360 312916aa2e6483390f88331e2af9a1df 493 Gene3D G3DSA:3.50.50.60 93 444 3.7E-15 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_05360 312916aa2e6483390f88331e2af9a1df 493 Pfam PF13454 FAD-NAD(P)-binding 11 173 4.0E-37 T 14-10-2018 IPR038732 FAD-dependent urate hydroxylase HpyO, FAD/NAD(P)-binding domain TSH58p_22095 be0c1337ff1cec498dd7ce82a593aa0c 144 Pfam PF11154 Protein of unknown function (DUF2934) 8 43 5.5E-15 T 14-10-2018 IPR021327 Protein of unknown function DUF2934 TSH58p_29325 2bfba5159d6e418156e83ad67ee31aee 137 Pfam PF04138 GtrA-like protein 17 130 5.2E-24 T 14-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 TSH58p_23925 ab4b2c0e1f77cbbb1078c6b88cf5ea92 287 SUPERFAMILY SSF102886 8 287 2.22E-114 T 14-10-2018 IPR036406 Oxygen-dependent coproporphyrinogen III oxidase superfamily GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 TSH58p_23925 ab4b2c0e1f77cbbb1078c6b88cf5ea92 287 Gene3D G3DSA:3.40.1500.10 1 287 6.0E-106 T 14-10-2018 IPR036406 Oxygen-dependent coproporphyrinogen III oxidase superfamily GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 TSH58p_23925 ab4b2c0e1f77cbbb1078c6b88cf5ea92 287 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 5 287 51.841 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 TSH58p_23925 ab4b2c0e1f77cbbb1078c6b88cf5ea92 287 Pfam PF01218 Coproporphyrinogen III oxidase 13 286 1.2E-92 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 TSH58p_23925 ab4b2c0e1f77cbbb1078c6b88cf5ea92 287 PIRSF PIRSF000166 2 287 2.9E-113 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 TSH58p_23925 ab4b2c0e1f77cbbb1078c6b88cf5ea92 287 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 176 200 - T 14-10-2018 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 TSH58p_23925 ab4b2c0e1f77cbbb1078c6b88cf5ea92 287 PRINTS PR00073 Coprogen oxidase signature 272 287 8.0E-45 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 TSH58p_23925 ab4b2c0e1f77cbbb1078c6b88cf5ea92 287 PRINTS PR00073 Coprogen oxidase signature 244 271 8.0E-45 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 TSH58p_23925 ab4b2c0e1f77cbbb1078c6b88cf5ea92 287 PRINTS PR00073 Coprogen oxidase signature 172 201 8.0E-45 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 TSH58p_23925 ab4b2c0e1f77cbbb1078c6b88cf5ea92 287 PRINTS PR00073 Coprogen oxidase signature 43 59 8.0E-45 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 TSH58p_23925 ab4b2c0e1f77cbbb1078c6b88cf5ea92 287 PRINTS PR00073 Coprogen oxidase signature 135 157 8.0E-45 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 TSH58p_13105 f126c3cbcf6c75e1b325a45dfc098873 397 Pfam PF07687 Peptidase dimerisation domain 195 302 3.2E-19 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain TSH58p_13105 f126c3cbcf6c75e1b325a45dfc098873 397 Pfam PF01546 Peptidase family M20/M25/M40 78 391 1.7E-45 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 TSH58p_13105 f126c3cbcf6c75e1b325a45dfc098873 397 Gene3D G3DSA:3.30.70.360 199 312 7.3E-115 T 14-10-2018 TSH58p_13105 f126c3cbcf6c75e1b325a45dfc098873 397 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 17 391 4.1E-127 T 14-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 TSH58p_13105 f126c3cbcf6c75e1b325a45dfc098873 397 SUPERFAMILY SSF53187 14 392 2.0E-61 T 14-10-2018 TSH58p_13105 f126c3cbcf6c75e1b325a45dfc098873 397 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 13 394 50.413 T 14-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 TSH58p_13105 f126c3cbcf6c75e1b325a45dfc098873 397 SUPERFAMILY SSF55031 199 306 4.04E-25 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TSH58p_13105 f126c3cbcf6c75e1b325a45dfc098873 397 Gene3D G3DSA:3.40.630.10 19 381 7.3E-115 T 14-10-2018 TSH58p_22360 ece66a498874f4cbf4155c40976eed28 950 ProSitePatterns PS00211 ABC transporters family signature. 488 502 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_22360 ece66a498874f4cbf4155c40976eed28 950 Gene3D G3DSA:3.30.190.20 131 243 1.6E-249 T 14-10-2018 TSH58p_22360 ece66a498874f4cbf4155c40976eed28 950 SUPERFAMILY SSF52540 618 913 7.42E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_22360 ece66a498874f4cbf4155c40976eed28 950 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 940 22.83 T 14-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 TSH58p_22360 ece66a498874f4cbf4155c40976eed28 950 SUPERFAMILY SSF52540 4 570 6.57E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_22360 ece66a498874f4cbf4155c40976eed28 950 ProSitePatterns PS00211 ABC transporters family signature. 830 844 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_22360 ece66a498874f4cbf4155c40976eed28 950 Gene3D G3DSA:1.10.8.280 286 402 1.6E-249 T 14-10-2018 TSH58p_22360 ece66a498874f4cbf4155c40976eed28 950 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 924 0.0 T 14-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 TSH58p_22360 ece66a498874f4cbf4155c40976eed28 950 Gene3D G3DSA:1.20.1580.10 692 830 1.7E-141 T 14-10-2018 TSH58p_22360 ece66a498874f4cbf4155c40976eed28 950 Gene3D G3DSA:3.40.50.300 7 595 1.6E-249 T 14-10-2018 TSH58p_22360 ece66a498874f4cbf4155c40976eed28 950 Gene3D G3DSA:1.20.1580.10 91 493 1.6E-249 T 14-10-2018 TSH58p_22360 ece66a498874f4cbf4155c40976eed28 950 Gene3D G3DSA:3.40.50.300 617 936 1.7E-141 T 14-10-2018 TSH58p_01225 9dd791093dc560ebf2d8e9d1385b1b83 235 Pfam PF00977 Histidine biosynthesis protein 4 225 7.9E-19 T 14-10-2018 IPR006062 Histidine biosynthesis GO:0000105 TSH58p_01225 9dd791093dc560ebf2d8e9d1385b1b83 235 Gene3D G3DSA:3.20.20.70 1 233 5.0E-37 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_01225 9dd791093dc560ebf2d8e9d1385b1b83 235 SUPERFAMILY SSF51366 3 225 4.08E-27 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TSH58p_30435 bc0e394114a34c1599e3dbc8b2e41c48 238 Pfam PF00005 ABC transporter 17 160 3.9E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_30435 bc0e394114a34c1599e3dbc8b2e41c48 238 SUPERFAMILY SSF52540 1 231 2.46E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_30435 bc0e394114a34c1599e3dbc8b2e41c48 238 SMART SM00382 26 209 2.4E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_30435 bc0e394114a34c1599e3dbc8b2e41c48 238 Gene3D G3DSA:3.40.50.300 1 232 3.2E-59 T 14-10-2018 TSH58p_30435 bc0e394114a34c1599e3dbc8b2e41c48 238 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_09355 439ce84566d792ee6bfc3e8f1d20e721 292 SUPERFAMILY SSF48179 168 290 2.27E-34 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_09355 439ce84566d792ee6bfc3e8f1d20e721 292 SUPERFAMILY SSF51735 11 168 1.0E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_09355 439ce84566d792ee6bfc3e8f1d20e721 292 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 14 27 - T 14-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 TSH58p_09355 439ce84566d792ee6bfc3e8f1d20e721 292 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 170 289 9.1E-32 T 14-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 TSH58p_09355 439ce84566d792ee6bfc3e8f1d20e721 292 Gene3D G3DSA:3.40.50.720 8 167 9.8E-54 T 14-10-2018 TSH58p_09355 439ce84566d792ee6bfc3e8f1d20e721 292 Gene3D G3DSA:1.10.1040.10 168 292 2.8E-36 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSH58p_09355 439ce84566d792ee6bfc3e8f1d20e721 292 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 11 167 1.2E-50 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 TSH58p_09355 439ce84566d792ee6bfc3e8f1d20e721 292 PIRSF PIRSF000103 6 292 2.0E-70 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 TSH58p_25070 b80e1102ab12685150ffd02e74e75b34 638 Gene3D G3DSA:1.25.40.10 6 123 1.1E-22 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25070 b80e1102ab12685150ffd02e74e75b34 638 Gene3D G3DSA:3.40.50.11350 499 625 2.7E-5 T 14-10-2018 TSH58p_25070 b80e1102ab12685150ffd02e74e75b34 638 Gene3D G3DSA:1.25.40.10 183 272 1.4E-14 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25070 b80e1102ab12685150ffd02e74e75b34 638 SMART SM00028 106 141 20.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25070 b80e1102ab12685150ffd02e74e75b34 638 SMART SM00028 176 209 0.55 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25070 b80e1102ab12685150ffd02e74e75b34 638 SMART SM00028 4 37 98.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25070 b80e1102ab12685150ffd02e74e75b34 638 SMART SM00028 72 105 4.4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25070 b80e1102ab12685150ffd02e74e75b34 638 SMART SM00028 38 71 9.7 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25070 b80e1102ab12685150ffd02e74e75b34 638 SMART SM00028 142 175 0.1 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25070 b80e1102ab12685150ffd02e74e75b34 638 SMART SM00028 210 243 1.4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25070 b80e1102ab12685150ffd02e74e75b34 638 SUPERFAMILY SSF48452 16 258 3.41E-36 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25070 b80e1102ab12685150ffd02e74e75b34 638 Gene3D G3DSA:1.25.40.10 124 182 1.4E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25070 b80e1102ab12685150ffd02e74e75b34 638 Pfam PF13432 Tetratricopeptide repeat 16 56 7.9E-6 T 14-10-2018 TSH58p_25070 b80e1102ab12685150ffd02e74e75b34 638 Pfam PF13432 Tetratricopeptide repeat 147 210 5.5E-7 T 14-10-2018 TSH58p_25070 b80e1102ab12685150ffd02e74e75b34 638 Pfam PF13432 Tetratricopeptide repeat 77 140 0.0034 T 14-10-2018 TSH58p_25070 b80e1102ab12685150ffd02e74e75b34 638 Pfam PF13432 Tetratricopeptide repeat 214 267 3.1E-5 T 14-10-2018 TSH58p_07135 ca23a2a352c9e5afeb816853377b3681 515 SUPERFAMILY SSF52540 47 157 7.38E-8 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_07135 ca23a2a352c9e5afeb816853377b3681 515 SUPERFAMILY SSF52540 46 286 3.55E-6 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_07135 ca23a2a352c9e5afeb816853377b3681 515 Gene3D G3DSA:3.40.50.300 25 184 8.4E-7 T 14-10-2018 TSH58p_07135 ca23a2a352c9e5afeb816853377b3681 515 Pfam PF00005 ABC transporter 46 173 5.4E-6 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_28340 b1cace442cb60e8369dae9cee2db9102 140 SUPERFAMILY SSF54919 1 139 1.96E-54 T 14-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSH58p_28340 b1cace442cb60e8369dae9cee2db9102 140 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 14-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSH58p_28340 b1cace442cb60e8369dae9cee2db9102 140 Gene3D G3DSA:3.30.70.141 1 138 8.7E-55 T 14-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSH58p_28340 b1cace442cb60e8369dae9cee2db9102 140 SMART SM00562 3 140 3.5E-82 T 14-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSH58p_28340 b1cace442cb60e8369dae9cee2db9102 140 Pfam PF00334 Nucleoside diphosphate kinase 4 135 7.1E-53 T 14-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSH58p_28340 b1cace442cb60e8369dae9cee2db9102 140 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 34.954 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSH58p_28340 b1cace442cb60e8369dae9cee2db9102 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 1.9E-37 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSH58p_28340 b1cace442cb60e8369dae9cee2db9102 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 1.9E-37 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSH58p_28340 b1cace442cb60e8369dae9cee2db9102 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 1.9E-37 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSH58p_28340 b1cace442cb60e8369dae9cee2db9102 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 1.9E-37 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSH58p_28340 b1cace442cb60e8369dae9cee2db9102 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 1.9E-37 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSH58p_08530 968f2bd2226b542a6edfc6983957c58f 218 SUPERFAMILY SSF88659 147 205 8.04E-17 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSH58p_08530 968f2bd2226b542a6edfc6983957c58f 218 Gene3D G3DSA:1.10.1740.10 30 150 2.4E-31 T 14-10-2018 TSH58p_08530 968f2bd2226b542a6edfc6983957c58f 218 Pfam PF04542 Sigma-70 region 2 53 118 1.4E-21 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_08530 968f2bd2226b542a6edfc6983957c58f 218 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 75 107 - T 14-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_08530 968f2bd2226b542a6edfc6983957c58f 218 Gene3D G3DSA:1.10.10.10 151 209 7.1E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_08530 968f2bd2226b542a6edfc6983957c58f 218 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 49 203 4.9E-34 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TSH58p_08530 968f2bd2226b542a6edfc6983957c58f 218 SUPERFAMILY SSF88946 30 132 2.67E-30 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_08530 968f2bd2226b542a6edfc6983957c58f 218 Pfam PF08281 Sigma-70, region 4 149 200 5.6E-15 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_01460 6eab51fa44bff047a4d3ff3cd9dbe1c5 407 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 56 274 1.7E-18 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain TSH58p_01460 6eab51fa44bff047a4d3ff3cd9dbe1c5 407 Gene3D G3DSA:2.40.420.20 54 391 3.4E-76 T 14-10-2018 TSH58p_01460 6eab51fa44bff047a4d3ff3cd9dbe1c5 407 Gene3D G3DSA:2.40.50.100 70 232 3.4E-76 T 14-10-2018 TSH58p_01460 6eab51fa44bff047a4d3ff3cd9dbe1c5 407 Gene3D G3DSA:1.10.287.470 104 195 3.4E-76 T 14-10-2018 TSH58p_01460 6eab51fa44bff047a4d3ff3cd9dbe1c5 407 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 47 274 3.7E-34 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 TSH58p_01460 6eab51fa44bff047a4d3ff3cd9dbe1c5 407 Gene3D G3DSA:2.40.30.170 59 328 3.4E-76 T 14-10-2018 TSH58p_01460 6eab51fa44bff047a4d3ff3cd9dbe1c5 407 SUPERFAMILY SSF111369 60 251 3.66E-20 T 14-10-2018 TSH58p_09990 7038cd2c2c9d22d5f99e57b4755f1a12 424 Gene3D G3DSA:2.160.20.80 255 424 3.0E-31 T 14-10-2018 TSH58p_09990 7038cd2c2c9d22d5f99e57b4755f1a12 424 Pfam PF00805 Pentapeptide repeats (8 copies) 189 221 2.5E-10 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_09990 7038cd2c2c9d22d5f99e57b4755f1a12 424 Pfam PF00805 Pentapeptide repeats (8 copies) 284 320 4.4E-4 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_09990 7038cd2c2c9d22d5f99e57b4755f1a12 424 Pfam PF00805 Pentapeptide repeats (8 copies) 149 188 8.6E-8 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_09990 7038cd2c2c9d22d5f99e57b4755f1a12 424 Pfam PF00805 Pentapeptide repeats (8 copies) 78 114 1.1E-10 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_09990 7038cd2c2c9d22d5f99e57b4755f1a12 424 Pfam PF00805 Pentapeptide repeats (8 copies) 323 360 1.1E-10 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_09990 7038cd2c2c9d22d5f99e57b4755f1a12 424 Pfam PF00805 Pentapeptide repeats (8 copies) 379 418 1.1E-7 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_09990 7038cd2c2c9d22d5f99e57b4755f1a12 424 Gene3D G3DSA:2.160.20.80 136 226 1.3E-21 T 14-10-2018 TSH58p_09990 7038cd2c2c9d22d5f99e57b4755f1a12 424 Gene3D G3DSA:2.160.20.80 8 135 2.7E-25 T 14-10-2018 TSH58p_09990 7038cd2c2c9d22d5f99e57b4755f1a12 424 SUPERFAMILY SSF141571 34 122 1.44E-22 T 14-10-2018 TSH58p_09990 7038cd2c2c9d22d5f99e57b4755f1a12 424 SUPERFAMILY SSF141571 144 226 8.63E-20 T 14-10-2018 TSH58p_09990 7038cd2c2c9d22d5f99e57b4755f1a12 424 SUPERFAMILY SSF141571 279 422 4.81E-27 T 14-10-2018 TSH58p_00085 8dddf94e1357f274b8f3b7a2faf80d04 705 Gene3D G3DSA:1.10.8.500 357 407 1.2E-16 T 14-10-2018 TSH58p_00085 8dddf94e1357f274b8f3b7a2faf80d04 705 SMART SM00283 445 699 6.0E-37 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_00085 8dddf94e1357f274b8f3b7a2faf80d04 705 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 514 668 1.5E-27 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_00085 8dddf94e1357f274b8f3b7a2faf80d04 705 Pfam PF00672 HAMP domain 356 405 5.4E-11 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_00085 8dddf94e1357f274b8f3b7a2faf80d04 705 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 572 601 1.3E-20 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_00085 8dddf94e1357f274b8f3b7a2faf80d04 705 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 466 495 1.3E-20 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_00085 8dddf94e1357f274b8f3b7a2faf80d04 705 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 620 649 1.3E-20 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_00085 8dddf94e1357f274b8f3b7a2faf80d04 705 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 543 570 1.3E-20 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_00085 8dddf94e1357f274b8f3b7a2faf80d04 705 SMART SM00304 356 409 9.3E-11 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_00085 8dddf94e1357f274b8f3b7a2faf80d04 705 SUPERFAMILY SSF58104 384 698 3.53E-58 T 14-10-2018 TSH58p_00085 8dddf94e1357f274b8f3b7a2faf80d04 705 Gene3D G3DSA:1.10.287.950 414 699 5.3E-54 T 14-10-2018 TSH58p_13485 a16c5b4e480e4b15d86c8e71680b0a85 246 Hamap MF_01146 Aquaporin Z [aqpZ]. 4 232 35.467 T 14-10-2018 IPR023743 Aquaporin Z GO:0006833|GO:0015250|GO:0016021|GO:0055085 TSH58p_13485 a16c5b4e480e4b15d86c8e71680b0a85 246 ProSitePatterns PS00221 MIP family signature. 63 71 - T 14-10-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 TSH58p_13485 a16c5b4e480e4b15d86c8e71680b0a85 246 PRINTS PR00783 Major intrinsic protein family signature 5 24 5.0E-54 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TSH58p_13485 a16c5b4e480e4b15d86c8e71680b0a85 246 PRINTS PR00783 Major intrinsic protein family signature 169 191 5.0E-54 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TSH58p_13485 a16c5b4e480e4b15d86c8e71680b0a85 246 PRINTS PR00783 Major intrinsic protein family signature 208 228 5.0E-54 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TSH58p_13485 a16c5b4e480e4b15d86c8e71680b0a85 246 PRINTS PR00783 Major intrinsic protein family signature 45 69 5.0E-54 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TSH58p_13485 a16c5b4e480e4b15d86c8e71680b0a85 246 PRINTS PR00783 Major intrinsic protein family signature 82 101 5.0E-54 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TSH58p_13485 a16c5b4e480e4b15d86c8e71680b0a85 246 PRINTS PR00783 Major intrinsic protein family signature 139 157 5.0E-54 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TSH58p_13485 a16c5b4e480e4b15d86c8e71680b0a85 246 SUPERFAMILY SSF81338 4 228 1.83E-70 T 14-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 TSH58p_13485 a16c5b4e480e4b15d86c8e71680b0a85 246 Pfam PF00230 Major intrinsic protein 3 225 7.5E-54 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TSH58p_13485 a16c5b4e480e4b15d86c8e71680b0a85 246 TIGRFAM TIGR00861 MIP: MIP family channel proteins 9 225 3.1E-64 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TSH58p_13485 a16c5b4e480e4b15d86c8e71680b0a85 246 Gene3D G3DSA:1.20.1080.10 1 232 4.0E-88 T 14-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 TSH58p_28305 132358aa3d73b339b88dda0053c6be90 292 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 37 288 1.2E-70 T 14-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 TSH58p_28305 132358aa3d73b339b88dda0053c6be90 292 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 36 290 51.442 T 14-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 TSH58p_28305 132358aa3d73b339b88dda0053c6be90 292 SMART SM00650 52 224 3.1E-66 T 14-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 TSH58p_28305 132358aa3d73b339b88dda0053c6be90 292 Pfam PF00398 Ribosomal RNA adenine dimethylase 37 286 2.4E-51 T 14-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm TSH58p_28305 132358aa3d73b339b88dda0053c6be90 292 Gene3D G3DSA:1.10.8.100 228 292 5.5E-20 T 14-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 TSH58p_28305 132358aa3d73b339b88dda0053c6be90 292 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 68 96 - T 14-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 TSH58p_28305 132358aa3d73b339b88dda0053c6be90 292 SUPERFAMILY SSF53335 33 291 8.21E-72 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_28305 132358aa3d73b339b88dda0053c6be90 292 Gene3D G3DSA:3.40.50.150 15 227 7.8E-69 T 14-10-2018 TSH58p_00025 c7e7fd43a35b1a10a37791de4fa24d2e 258 Gene3D G3DSA:3.40.50.720 1 257 8.3E-79 T 14-10-2018 TSH58p_00025 c7e7fd43a35b1a10a37791de4fa24d2e 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 254 3.1E-47 T 14-10-2018 TSH58p_00025 c7e7fd43a35b1a10a37791de4fa24d2e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 4.4E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00025 c7e7fd43a35b1a10a37791de4fa24d2e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 4.4E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00025 c7e7fd43a35b1a10a37791de4fa24d2e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 4.4E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00025 c7e7fd43a35b1a10a37791de4fa24d2e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 4.4E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00025 c7e7fd43a35b1a10a37791de4fa24d2e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.4E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00025 c7e7fd43a35b1a10a37791de4fa24d2e 258 SUPERFAMILY SSF51735 6 257 8.16E-68 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_03385 c7e7fd43a35b1a10a37791de4fa24d2e 258 Gene3D G3DSA:3.40.50.720 1 257 8.3E-79 T 14-10-2018 TSH58p_03385 c7e7fd43a35b1a10a37791de4fa24d2e 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 254 3.1E-47 T 14-10-2018 TSH58p_03385 c7e7fd43a35b1a10a37791de4fa24d2e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 4.4E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03385 c7e7fd43a35b1a10a37791de4fa24d2e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 4.4E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03385 c7e7fd43a35b1a10a37791de4fa24d2e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 4.4E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03385 c7e7fd43a35b1a10a37791de4fa24d2e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 4.4E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03385 c7e7fd43a35b1a10a37791de4fa24d2e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.4E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03385 c7e7fd43a35b1a10a37791de4fa24d2e 258 SUPERFAMILY SSF51735 6 257 8.16E-68 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_18785 8d82690029c0b5799a96282b44abbc58 345 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 125 227 4.7E-23 T 14-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_18785 8d82690029c0b5799a96282b44abbc58 345 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 42 240 3.5E-47 T 14-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_18785 8d82690029c0b5799a96282b44abbc58 345 Pfam PF00034 Cytochrome c 256 345 6.9E-7 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_18785 8d82690029c0b5799a96282b44abbc58 345 SUPERFAMILY SSF49503 120 281 7.11E-50 T 14-10-2018 IPR008972 Cupredoxin TSH58p_18785 8d82690029c0b5799a96282b44abbc58 345 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 176 224 - T 14-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_18785 8d82690029c0b5799a96282b44abbc58 345 Gene3D G3DSA:2.60.40.2600 120 345 4.0E-76 T 14-10-2018 TSH58p_18785 8d82690029c0b5799a96282b44abbc58 345 PRINTS PR01166 Cytochrome c oxidase subunit II signature 175 195 5.1E-15 T 14-10-2018 TSH58p_18785 8d82690029c0b5799a96282b44abbc58 345 PRINTS PR01166 Cytochrome c oxidase subunit II signature 195 212 5.1E-15 T 14-10-2018 TSH58p_18785 8d82690029c0b5799a96282b44abbc58 345 PRINTS PR01166 Cytochrome c oxidase subunit II signature 119 138 5.1E-15 T 14-10-2018 TSH58p_18785 8d82690029c0b5799a96282b44abbc58 345 PRINTS PR01166 Cytochrome c oxidase subunit II signature 213 230 5.1E-15 T 14-10-2018 TSH58p_18785 8d82690029c0b5799a96282b44abbc58 345 SUPERFAMILY SSF46626 247 344 8.58E-17 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_09580 e5e6d1129c8488f9a40c30d4b5cbdbb8 935 SMART SM00387 793 905 4.5E-36 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_09580 e5e6d1129c8488f9a40c30d4b5cbdbb8 935 SMART SM00388 680 747 5.4E-21 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_09580 e5e6d1129c8488f9a40c30d4b5cbdbb8 935 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 793 904 2.5E-26 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_09580 e5e6d1129c8488f9a40c30d4b5cbdbb8 935 Gene3D G3DSA:1.20.1730.10 30 488 1.3E-15 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily TSH58p_09580 e5e6d1129c8488f9a40c30d4b5cbdbb8 935 Gene3D G3DSA:3.30.565.10 749 906 1.1E-43 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_09580 e5e6d1129c8488f9a40c30d4b5cbdbb8 935 Pfam PF00512 His Kinase A (phospho-acceptor) domain 681 747 2.3E-17 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_09580 e5e6d1129c8488f9a40c30d4b5cbdbb8 935 Gene3D G3DSA:1.10.287.130 665 748 5.1E-24 T 14-10-2018 TSH58p_09580 e5e6d1129c8488f9a40c30d4b5cbdbb8 935 PRINTS PR00344 Bacterial sensor protein C-terminal signature 830 844 5.5E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_09580 e5e6d1129c8488f9a40c30d4b5cbdbb8 935 PRINTS PR00344 Bacterial sensor protein C-terminal signature 865 883 5.5E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_09580 e5e6d1129c8488f9a40c30d4b5cbdbb8 935 PRINTS PR00344 Bacterial sensor protein C-terminal signature 889 902 5.5E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_09580 e5e6d1129c8488f9a40c30d4b5cbdbb8 935 SUPERFAMILY SSF47384 666 748 8.83E-20 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_09580 e5e6d1129c8488f9a40c30d4b5cbdbb8 935 SUPERFAMILY SSF55874 736 904 5.24E-46 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_07615 8956b5cc0b2222994caa955eaaa5e57b 142 TIGRFAM TIGR01616 nitro_assoc: nitrogenase-associated protein 2 128 1.1E-56 T 14-10-2018 IPR006503 Nitrogenase-associated protein TSH58p_07615 8956b5cc0b2222994caa955eaaa5e57b 142 SUPERFAMILY SSF52833 3 118 2.24E-30 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_07615 8956b5cc0b2222994caa955eaaa5e57b 142 Pfam PF03960 ArsC family 59 112 3.1E-8 T 14-10-2018 IPR006660 Arsenate reductase-like TSH58p_07615 8956b5cc0b2222994caa955eaaa5e57b 142 Gene3D G3DSA:3.40.30.10 1 114 9.1E-18 T 14-10-2018 TSH58p_15420 3e227d132970449585e2628a79074c77 360 SUPERFAMILY SSF101801 280 355 1.02E-12 T 14-10-2018 IPR036429 SpoA-like superfamily TSH58p_15420 3e227d132970449585e2628a79074c77 360 Pfam PF02154 Flagellar motor switch protein FliM 70 260 8.3E-66 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 TSH58p_15420 3e227d132970449585e2628a79074c77 360 Gene3D G3DSA:3.40.1550.10 75 261 1.1E-52 T 14-10-2018 IPR028976 CheC-like superfamily TSH58p_15420 3e227d132970449585e2628a79074c77 360 PRINTS PR00955 Flagellar motor switch protein FliM signature 118 134 3.9E-23 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 TSH58p_15420 3e227d132970449585e2628a79074c77 360 PRINTS PR00955 Flagellar motor switch protein FliM signature 39 52 3.9E-23 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 TSH58p_15420 3e227d132970449585e2628a79074c77 360 PRINTS PR00955 Flagellar motor switch protein FliM signature 143 162 3.9E-23 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 TSH58p_15420 3e227d132970449585e2628a79074c77 360 PRINTS PR00955 Flagellar motor switch protein FliM signature 242 260 3.9E-23 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 TSH58p_15420 3e227d132970449585e2628a79074c77 360 SUPERFAMILY SSF103039 78 260 6.54E-11 T 14-10-2018 IPR028976 CheC-like superfamily TSH58p_15420 3e227d132970449585e2628a79074c77 360 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 40 352 8.3E-91 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 TSH58p_15420 3e227d132970449585e2628a79074c77 360 PIRSF PIRSF002888 38 359 2.7E-91 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 TSH58p_15420 3e227d132970449585e2628a79074c77 360 Gene3D G3DSA:2.30.330.10 274 358 1.5E-5 T 14-10-2018 IPR036429 SpoA-like superfamily TSH58p_15420 3e227d132970449585e2628a79074c77 360 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 283 350 6.6E-18 T 14-10-2018 IPR001543 Surface presentation of antigen (SpoA) TSH58p_12495 42954f64a3a0632cecc94276c0ecfe56 335 Pfam PF03186 CobD/Cbib protein 24 313 8.0E-64 T 14-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 TSH58p_12495 42954f64a3a0632cecc94276c0ecfe56 335 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 334 62.987 T 14-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 TSH58p_05675 181a2f37c39d7114a03deb90edfde7a0 437 SUPERFAMILY SSF48256 12 436 7.46E-168 T 14-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 TSH58p_05675 181a2f37c39d7114a03deb90edfde7a0 437 Gene3D G3DSA:2.20.28.60 2 57 3.1E-21 T 14-10-2018 TSH58p_05675 181a2f37c39d7114a03deb90edfde7a0 437 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 20 430 7.2E-237 T 14-10-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 TSH58p_05675 181a2f37c39d7114a03deb90edfde7a0 437 Pfam PF00285 Citrate synthase, C-terminal domain 53 419 1.6E-133 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 TSH58p_05675 181a2f37c39d7114a03deb90edfde7a0 437 ProSitePatterns PS00480 Citrate synthase signature. 310 322 - T 14-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 TSH58p_05675 181a2f37c39d7114a03deb90edfde7a0 437 PIRSF PIRSF001369 44 437 3.6E-169 T 14-10-2018 IPR024176 Citrate synthase, bacterial-type TSH58p_05675 181a2f37c39d7114a03deb90edfde7a0 437 PRINTS PR00143 Citrate synthase signature 226 241 1.3E-56 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 TSH58p_05675 181a2f37c39d7114a03deb90edfde7a0 437 PRINTS PR00143 Citrate synthase signature 367 383 1.3E-56 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 TSH58p_05675 181a2f37c39d7114a03deb90edfde7a0 437 PRINTS PR00143 Citrate synthase signature 387 401 1.3E-56 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 TSH58p_05675 181a2f37c39d7114a03deb90edfde7a0 437 PRINTS PR00143 Citrate synthase signature 172 185 1.3E-56 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 TSH58p_05675 181a2f37c39d7114a03deb90edfde7a0 437 PRINTS PR00143 Citrate synthase signature 303 323 1.3E-56 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 TSH58p_05675 181a2f37c39d7114a03deb90edfde7a0 437 PRINTS PR00143 Citrate synthase signature 248 276 1.3E-56 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 TSH58p_05675 181a2f37c39d7114a03deb90edfde7a0 437 Gene3D G3DSA:1.10.230.10 275 384 1.6E-146 T 14-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain TSH58p_05675 181a2f37c39d7114a03deb90edfde7a0 437 Gene3D G3DSA:1.10.580.10 64 419 1.6E-146 T 14-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 TSH58p_25230 5641cb6d0f604feec016aad24f95e167 447 Pfam PF05711 Macrocin-O-methyltransferase (TylF) 345 423 1.6E-5 T 14-10-2018 IPR008884 Macrocin-O-methyltransferase TSH58p_25230 5641cb6d0f604feec016aad24f95e167 447 SUPERFAMILY SSF53335 281 420 5.81E-9 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_25230 5641cb6d0f604feec016aad24f95e167 447 SUPERFAMILY SSF48452 45 245 7.02E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25230 5641cb6d0f604feec016aad24f95e167 447 Gene3D G3DSA:3.40.50.150 269 436 8.7E-30 T 14-10-2018 TSH58p_25230 5641cb6d0f604feec016aad24f95e167 447 Gene3D G3DSA:1.25.40.10 8 264 1.2E-21 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_27130 367ea4325a721ac88a00202206ffb2e5 424 Gene3D G3DSA:1.10.240.10 236 329 2.0E-28 T 14-10-2018 TSH58p_27130 367ea4325a721ac88a00202206ffb2e5 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 229 241 7.2E-27 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TSH58p_27130 367ea4325a721ac88a00202206ffb2e5 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 175 190 7.2E-27 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TSH58p_27130 367ea4325a721ac88a00202206ffb2e5 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 54 76 7.2E-27 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TSH58p_27130 367ea4325a721ac88a00202206ffb2e5 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 196 218 7.2E-27 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TSH58p_27130 367ea4325a721ac88a00202206ffb2e5 424 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 13 421 1.6E-104 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TSH58p_27130 367ea4325a721ac88a00202206ffb2e5 424 Gene3D G3DSA:3.10.290.10 330 423 4.6E-17 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TSH58p_27130 367ea4325a721ac88a00202206ffb2e5 424 Pfam PF00579 tRNA synthetases class I (W and Y) 39 334 1.6E-72 T 14-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_27130 367ea4325a721ac88a00202206ffb2e5 424 Gene3D G3DSA:3.40.50.620 2 235 7.6E-86 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_27130 367ea4325a721ac88a00202206ffb2e5 424 Pfam PF01479 S4 domain 357 402 1.1E-9 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_27130 367ea4325a721ac88a00202206ffb2e5 424 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 12 423 42.272 T 14-10-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 TSH58p_27130 367ea4325a721ac88a00202206ffb2e5 424 SUPERFAMILY SSF55174 329 421 1.83E-16 T 14-10-2018 TSH58p_27130 367ea4325a721ac88a00202206ffb2e5 424 SUPERFAMILY SSF52374 13 334 2.33E-93 T 14-10-2018 TSH58p_03320 b9388a0958cc3ab004dfaf039421c502 962 Gene3D G3DSA:3.30.70.2740 394 477 1.6E-8 T 14-10-2018 TSH58p_03320 b9388a0958cc3ab004dfaf039421c502 962 SUPERFAMILY SSF46548 503 626 1.46E-22 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSH58p_03320 b9388a0958cc3ab004dfaf039421c502 962 Gene3D G3DSA:1.10.45.10 478 514 1.2E-6 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 TSH58p_03320 b9388a0958cc3ab004dfaf039421c502 962 SUPERFAMILY SSF55103 272 523 1.28E-55 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 TSH58p_03320 b9388a0958cc3ab004dfaf039421c502 962 Pfam PF02913 FAD linked oxidases, C-terminal domain 268 516 7.7E-54 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 TSH58p_03320 b9388a0958cc3ab004dfaf039421c502 962 SUPERFAMILY SSF56176 7 266 2.21E-56 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TSH58p_03320 b9388a0958cc3ab004dfaf039421c502 962 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 542 553 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_03320 b9388a0958cc3ab004dfaf039421c502 962 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 599 610 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_03320 b9388a0958cc3ab004dfaf039421c502 962 Pfam PF01565 FAD binding domain 43 179 5.8E-28 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TSH58p_03320 b9388a0958cc3ab004dfaf039421c502 962 Pfam PF02754 Cysteine-rich domain 846 923 0.015 T 14-10-2018 IPR004017 Cysteine-rich domain TSH58p_03320 b9388a0958cc3ab004dfaf039421c502 962 Gene3D G3DSA:3.30.465.40 6 199 7.8E-28 T 14-10-2018 TSH58p_03320 b9388a0958cc3ab004dfaf039421c502 962 Pfam PF13183 4Fe-4S dicluster domain 540 613 1.4E-10 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_03320 b9388a0958cc3ab004dfaf039421c502 962 Gene3D G3DSA:1.10.1060.10 515 631 1.9E-9 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSH58p_14950 c667cc9dee24a0d849eec12c449f7d42 248 SUPERFAMILY SSF52540 6 246 2.83E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_14950 c667cc9dee24a0d849eec12c449f7d42 248 Pfam PF00005 ABC transporter 23 178 2.7E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_14950 c667cc9dee24a0d849eec12c449f7d42 248 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 7 248 5.6E-114 T 14-10-2018 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD TSH58p_14950 c667cc9dee24a0d849eec12c449f7d42 248 Gene3D G3DSA:3.40.50.300 2 248 8.7E-55 T 14-10-2018 TSH58p_14950 c667cc9dee24a0d849eec12c449f7d42 248 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 226 247 8.1E-6 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSH58p_02280 5dc304d3b0eea41fe845de776e9ac4b3 706 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 79 345 5.9E-32 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TSH58p_02280 5dc304d3b0eea41fe845de776e9ac4b3 706 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 433 626 1.6E-43 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TSH58p_02280 5dc304d3b0eea41fe845de776e9ac4b3 706 ProSitePatterns PS01229 Hypothetical cof family signature 2. 540 562 - T 14-10-2018 TSH58p_02280 5dc304d3b0eea41fe845de776e9ac4b3 706 SUPERFAMILY SSF56784 297 583 2.47E-35 T 14-10-2018 IPR036412 HAD-like superfamily TSH58p_02280 5dc304d3b0eea41fe845de776e9ac4b3 706 Pfam PF00122 E1-E2 ATPase 109 288 9.8E-35 T 14-10-2018 TSH58p_02280 5dc304d3b0eea41fe845de776e9ac4b3 706 Gene3D G3DSA:2.70.150.20 109 216 1.5E-27 T 14-10-2018 TSH58p_02280 5dc304d3b0eea41fe845de776e9ac4b3 706 SUPERFAMILY SSF81653 117 211 6.02E-23 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 TSH58p_02280 5dc304d3b0eea41fe845de776e9ac4b3 706 SUPERFAMILY SSF81665 55 303 7.19E-8 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 TSH58p_02280 5dc304d3b0eea41fe845de776e9ac4b3 706 Gene3D G3DSA:1.20.1110.10 585 629 1.9E-22 T 14-10-2018 TSH58p_02280 5dc304d3b0eea41fe845de776e9ac4b3 706 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 16 704 41.669 T 14-10-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 TSH58p_02280 5dc304d3b0eea41fe845de776e9ac4b3 706 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 311 317 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 TSH58p_02280 5dc304d3b0eea41fe845de776e9ac4b3 706 Pfam PF00702 haloacid dehalogenase-like hydrolase 305 554 3.4E-30 T 14-10-2018 TSH58p_02280 5dc304d3b0eea41fe845de776e9ac4b3 706 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 14 700 0.0 T 14-10-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 TSH58p_02280 5dc304d3b0eea41fe845de776e9ac4b3 706 Gene3D G3DSA:3.40.1110.10 320 475 3.5E-51 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TSH58p_02280 5dc304d3b0eea41fe845de776e9ac4b3 706 Gene3D G3DSA:3.40.50.1000 515 584 1.9E-22 T 14-10-2018 IPR023214 HAD superfamily TSH58p_02280 5dc304d3b0eea41fe845de776e9ac4b3 706 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 309 323 4.8E-22 T 14-10-2018 TSH58p_02280 5dc304d3b0eea41fe845de776e9ac4b3 706 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 540 559 4.8E-22 T 14-10-2018 TSH58p_02280 5dc304d3b0eea41fe845de776e9ac4b3 706 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 158 172 4.8E-22 T 14-10-2018 TSH58p_02280 5dc304d3b0eea41fe845de776e9ac4b3 706 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 487 497 4.8E-22 T 14-10-2018 TSH58p_02280 5dc304d3b0eea41fe845de776e9ac4b3 706 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 563 575 4.8E-22 T 14-10-2018 TSH58p_06040 860ea5c907f62a2b2bc53ca1536a87da 455 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 4 133 2.4E-41 T 14-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_06040 860ea5c907f62a2b2bc53ca1536a87da 455 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 2 448 45.934 T 14-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_06040 860ea5c907f62a2b2bc53ca1536a87da 455 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 96 105 - T 14-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_06040 860ea5c907f62a2b2bc53ca1536a87da 455 Gene3D G3DSA:3.40.120.10 176 359 3.3E-65 T 14-10-2018 TSH58p_06040 860ea5c907f62a2b2bc53ca1536a87da 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 236 251 8.6E-13 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_06040 860ea5c907f62a2b2bc53ca1536a87da 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 95 109 8.6E-13 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_06040 860ea5c907f62a2b2bc53ca1536a87da 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 176 195 8.6E-13 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_06040 860ea5c907f62a2b2bc53ca1536a87da 455 Gene3D G3DSA:3.40.120.10 3 145 1.5E-45 T 14-10-2018 TSH58p_06040 860ea5c907f62a2b2bc53ca1536a87da 455 Gene3D G3DSA:3.30.310.50 374 450 1.6E-22 T 14-10-2018 TSH58p_06040 860ea5c907f62a2b2bc53ca1536a87da 455 SUPERFAMILY SSF55957 363 448 5.1E-21 T 14-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_06040 860ea5c907f62a2b2bc53ca1536a87da 455 SUPERFAMILY SSF53738 158 259 2.08E-30 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_06040 860ea5c907f62a2b2bc53ca1536a87da 455 Gene3D G3DSA:3.40.120.10 259 342 3.3E-65 T 14-10-2018 TSH58p_06040 860ea5c907f62a2b2bc53ca1536a87da 455 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 6 446 1.0E-186 T 14-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_06040 860ea5c907f62a2b2bc53ca1536a87da 455 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 377 445 5.6E-15 T 14-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_06040 860ea5c907f62a2b2bc53ca1536a87da 455 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 260 368 5.9E-34 T 14-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_06040 860ea5c907f62a2b2bc53ca1536a87da 455 SUPERFAMILY SSF53738 260 360 2.75E-30 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_06040 860ea5c907f62a2b2bc53ca1536a87da 455 SUPERFAMILY SSF53738 2 183 1.1E-47 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_06040 860ea5c907f62a2b2bc53ca1536a87da 455 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 159 256 1.2E-19 T 14-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_06765 7854ca712302c2e8fbdfecbf41806810 560 SMART SM00304 211 264 1.1E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_06765 7854ca712302c2e8fbdfecbf41806810 560 SUPERFAMILY SSF58104 241 553 1.96E-56 T 14-10-2018 TSH58p_06765 7854ca712302c2e8fbdfecbf41806810 560 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 365 522 2.4E-27 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_06765 7854ca712302c2e8fbdfecbf41806810 560 Gene3D G3DSA:1.20.1480.50 173 269 1.2E-16 T 14-10-2018 TSH58p_06765 7854ca712302c2e8fbdfecbf41806810 560 SMART SM00283 307 554 5.7E-45 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_06765 7854ca712302c2e8fbdfecbf41806810 560 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 321 350 8.8E-22 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_06765 7854ca712302c2e8fbdfecbf41806810 560 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 427 456 8.8E-22 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_06765 7854ca712302c2e8fbdfecbf41806810 560 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 475 504 8.8E-22 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_06765 7854ca712302c2e8fbdfecbf41806810 560 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 16 41 8.8E-22 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_06765 7854ca712302c2e8fbdfecbf41806810 560 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 398 425 8.8E-22 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_06765 7854ca712302c2e8fbdfecbf41806810 560 Gene3D G3DSA:1.10.287.950 270 558 7.8E-52 T 14-10-2018 TSH58p_06765 7854ca712302c2e8fbdfecbf41806810 560 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 166 2.1E-10 T 14-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain TSH58p_06765 7854ca712302c2e8fbdfecbf41806810 560 Pfam PF00672 HAMP domain 211 259 2.1E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_18640 2acab21b6a49e10ebde9ce3ca2fefb73 492 Gene3D G3DSA:3.30.70.20 219 296 4.1E-5 T 14-10-2018 TSH58p_18640 2acab21b6a49e10ebde9ce3ca2fefb73 492 Pfam PF12801 4Fe-4S binding domain 100 140 3.2E-11 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_18640 2acab21b6a49e10ebde9ce3ca2fefb73 492 Pfam PF13746 4Fe-4S dicluster domain 222 330 7.7E-42 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_18640 2acab21b6a49e10ebde9ce3ca2fefb73 492 SUPERFAMILY SSF54862 109 338 2.72E-27 T 14-10-2018 TSH58p_18640 2acab21b6a49e10ebde9ce3ca2fefb73 492 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 278 289 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_18640 2acab21b6a49e10ebde9ce3ca2fefb73 492 Gene3D G3DSA:2.60.40.10 368 492 5.1E-20 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_18640 2acab21b6a49e10ebde9ce3ca2fefb73 492 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 39 491 9.3E-152 T 14-10-2018 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021|GO:0055114 TSH58p_18640 2acab21b6a49e10ebde9ce3ca2fefb73 492 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 366 492 2.4E-28 T 14-10-2018 IPR032879 FixG, C-terminal immunoglobulin-like domain TSH58p_30660 881a3d9c25a0599d48e274d0b6ce2922 352 Pfam PF13343 Bacterial extracellular solute-binding protein 84 308 9.9E-21 T 14-10-2018 TSH58p_30660 881a3d9c25a0599d48e274d0b6ce2922 352 Gene3D G3DSA:3.40.190.10 37 316 1.1E-59 T 14-10-2018 TSH58p_30660 881a3d9c25a0599d48e274d0b6ce2922 352 SUPERFAMILY SSF53850 29 346 1.48E-45 T 14-10-2018 TSH58p_30660 881a3d9c25a0599d48e274d0b6ce2922 352 Gene3D G3DSA:3.40.190.10 137 329 1.1E-59 T 14-10-2018 TSH58p_27405 6dc2d6897452281d4d74a1997e952ca3 562 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 63 547 1.9E-139 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 TSH58p_27405 6dc2d6897452281d4d74a1997e952ca3 562 SUPERFAMILY SSF103473 46 552 1.22E-61 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_27405 6dc2d6897452281d4d74a1997e952ca3 562 Gene3D G3DSA:1.20.1250.20 313 479 6.6E-18 T 14-10-2018 TSH58p_27405 6dc2d6897452281d4d74a1997e952ca3 562 Pfam PF07690 Major Facilitator Superfamily 68 460 4.2E-45 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_27405 6dc2d6897452281d4d74a1997e952ca3 562 Gene3D G3DSA:1.20.1720.10 63 303 3.3E-37 T 14-10-2018 TSH58p_11365 fa40e03bd7778841b016639841f09b84 162 SUPERFAMILY SSF47413 16 93 1.64E-28 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_11365 fa40e03bd7778841b016639841f09b84 162 Pfam PF01381 Helix-turn-helix 33 85 5.9E-12 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_11365 fa40e03bd7778841b016639841f09b84 162 SMART SM00530 31 86 1.4E-12 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_11365 fa40e03bd7778841b016639841f09b84 162 Gene3D G3DSA:1.10.260.40 22 91 4.7E-15 T 14-10-2018 TSH58p_13875 7689c1eea81c7c2bc4ec0c279d83879a 147 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 64 141 2.3E-15 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_13875 7689c1eea81c7c2bc4ec0c279d83879a 147 Gene3D G3DSA:1.10.760.10 51 147 7.2E-19 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_13875 7689c1eea81c7c2bc4ec0c279d83879a 147 SUPERFAMILY SSF46626 9 144 1.3E-18 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_13875 7689c1eea81c7c2bc4ec0c279d83879a 147 TIGRFAM TIGR04494 c550_PedF: cytochrome c-550 PedF 18 147 2.7E-63 T 14-10-2018 IPR030991 Cytochrome c-550 PedF TSH58p_23840 4e00d50ef4254d3ca2ea095179f13b9b 77 Gene3D G3DSA:3.30.420.470 3 70 4.2E-9 T 14-10-2018 TSH58p_23840 4e00d50ef4254d3ca2ea095179f13b9b 77 Pfam PF13358 DDE superfamily endonuclease 5 44 7.0E-10 T 14-10-2018 IPR038717 Tc1-like transposase, DDE domain TSH58p_02660 057110704f755ae671280af8544491e0 240 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 26 235 4.9E-65 T 14-10-2018 IPR006214 Bax inhibitor 1-related TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 PRINTS PR01488 Gram-negative bacterial RTX toxin determinant A family signature 97 115 8.1E-5 T 14-10-2018 IPR003995 RTX toxin determinant A GO:0005509|GO:0005576|GO:0009405 TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 PRINTS PR01488 Gram-negative bacterial RTX toxin determinant A family signature 523 544 8.1E-5 T 14-10-2018 IPR003995 RTX toxin determinant A GO:0005509|GO:0005576|GO:0009405 TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 519 537 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 Gene3D G3DSA:2.150.10.10 360 445 3.0E-17 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 Gene3D G3DSA:2.150.10.10 147 267 1.3E-17 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 SUPERFAMILY SSF51120 348 427 1.57E-16 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 SUPERFAMILY SSF51120 248 361 2.75E-22 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 PRINTS PR00313 NodO calcium binding signature 381 390 1.0E-11 T 14-10-2018 TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 PRINTS PR00313 NodO calcium binding signature 182 193 1.0E-11 T 14-10-2018 TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 PRINTS PR00313 NodO calcium binding signature 309 317 1.0E-11 T 14-10-2018 TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 PRINTS PR00313 NodO calcium binding signature 345 353 1.0E-11 T 14-10-2018 TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 SUPERFAMILY SSF51120 449 563 1.96E-23 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 300 316 0.0031 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 568 580 0.22 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 398 413 2.1 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 326 343 0.011 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 523 539 0.1 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 168 183 21.0 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 477 494 0.092 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 185 201 0.0042 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 362 378 0.21 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 840 856 0.064 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 202 219 0.088 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 504 521 0.14 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 541 557 2.0 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 380 397 0.0051 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 345 361 0.014 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 SUPERFAMILY SSF51120 568 926 3.4E-17 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 Pfam PF14252 Domain of unknown function (DUF4347) 4 147 5.4E-29 T 14-10-2018 IPR025592 Domain of unknown function DUF4347 TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 Gene3D G3DSA:2.150.10.10 775 939 3.6E-13 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 190 208 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 SUPERFAMILY SSF51120 164 237 7.06E-16 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 Gene3D G3DSA:2.150.10.10 505 658 6.1E-16 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 Gene3D G3DSA:2.150.10.10 316 359 1.3E-12 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 Gene3D G3DSA:2.150.10.10 446 504 1.6E-10 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_18030 d15ed491165c50448abc4b33d0e6f306 958 Gene3D G3DSA:2.150.10.10 268 315 5.0E-7 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_21420 cd967ef683d875a9ff32703762c97648 111 Pfam PF07883 Cupin domain 36 102 3.3E-13 T 14-10-2018 IPR013096 Cupin 2, conserved barrel TSH58p_21420 cd967ef683d875a9ff32703762c97648 111 SUPERFAMILY SSF51182 9 108 6.33E-23 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_21420 cd967ef683d875a9ff32703762c97648 111 Gene3D G3DSA:2.60.120.10 2 111 3.3E-34 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_21420 cd967ef683d875a9ff32703762c97648 111 PIRSF PIRSF029883 3 111 2.9E-35 T 14-10-2018 IPR025499 Pectin degradation protein KdgF TSH58p_18540 cd967ef683d875a9ff32703762c97648 111 Pfam PF07883 Cupin domain 36 102 3.3E-13 T 14-10-2018 IPR013096 Cupin 2, conserved barrel TSH58p_18540 cd967ef683d875a9ff32703762c97648 111 SUPERFAMILY SSF51182 9 108 6.33E-23 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_18540 cd967ef683d875a9ff32703762c97648 111 Gene3D G3DSA:2.60.120.10 2 111 3.3E-34 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_18540 cd967ef683d875a9ff32703762c97648 111 PIRSF PIRSF029883 3 111 2.9E-35 T 14-10-2018 IPR025499 Pectin degradation protein KdgF TSH58p_13145 2ae35b20dc94e6d614bdf7a987f229f4 455 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 3.5E-22 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSH58p_13145 2ae35b20dc94e6d614bdf7a987f229f4 455 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 447 33.362 T 14-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 TSH58p_13145 2ae35b20dc94e6d614bdf7a987f229f4 455 Pfam PF02978 Signal peptide binding domain 328 427 1.5E-32 T 14-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TSH58p_13145 2ae35b20dc94e6d614bdf7a987f229f4 455 SUPERFAMILY SSF52540 42 354 2.92E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_13145 2ae35b20dc94e6d614bdf7a987f229f4 455 Pfam PF00448 SRP54-type protein, GTPase domain 102 295 1.0E-68 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSH58p_13145 2ae35b20dc94e6d614bdf7a987f229f4 455 Gene3D G3DSA:1.20.120.140 5 305 5.4E-118 T 14-10-2018 TSH58p_13145 2ae35b20dc94e6d614bdf7a987f229f4 455 SMART SM00963 1 86 3.6E-37 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSH58p_13145 2ae35b20dc94e6d614bdf7a987f229f4 455 SUPERFAMILY SSF47446 328 428 3.92E-37 T 14-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TSH58p_13145 2ae35b20dc94e6d614bdf7a987f229f4 455 Gene3D G3DSA:3.40.50.300 90 284 5.4E-118 T 14-10-2018 TSH58p_13145 2ae35b20dc94e6d614bdf7a987f229f4 455 SMART SM00382 98 245 5.1E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_13145 2ae35b20dc94e6d614bdf7a987f229f4 455 SMART SM00962 99 295 2.9E-106 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSH58p_13145 2ae35b20dc94e6d614bdf7a987f229f4 455 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 268 281 - T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSH58p_13145 2ae35b20dc94e6d614bdf7a987f229f4 455 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 429 8.0E-182 T 14-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 TSH58p_13145 2ae35b20dc94e6d614bdf7a987f229f4 455 Gene3D G3DSA:1.10.260.30 327 449 1.7E-43 T 14-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TSH58p_18535 34ee72e788fcdaf2f6a955cea7618e71 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_18535 34ee72e788fcdaf2f6a955cea7618e71 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 188 2.4E-4 T 14-10-2018 TSH58p_18535 34ee72e788fcdaf2f6a955cea7618e71 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 249 1.6E-58 T 14-10-2018 TSH58p_18535 34ee72e788fcdaf2f6a955cea7618e71 252 SUPERFAMILY SSF51735 5 251 4.76E-79 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_18535 34ee72e788fcdaf2f6a955cea7618e71 252 Gene3D G3DSA:3.40.50.720 1 252 1.0E-80 T 14-10-2018 TSH58p_18535 34ee72e788fcdaf2f6a955cea7618e71 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.4E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_18535 34ee72e788fcdaf2f6a955cea7618e71 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.4E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_18535 34ee72e788fcdaf2f6a955cea7618e71 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.4E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_18535 34ee72e788fcdaf2f6a955cea7618e71 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.7E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_18535 34ee72e788fcdaf2f6a955cea7618e71 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 2.7E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_18535 34ee72e788fcdaf2f6a955cea7618e71 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 2.7E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_18535 34ee72e788fcdaf2f6a955cea7618e71 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.7E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_18535 34ee72e788fcdaf2f6a955cea7618e71 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.7E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_18535 34ee72e788fcdaf2f6a955cea7618e71 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.7E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_18535 34ee72e788fcdaf2f6a955cea7618e71 252 TIGRFAM TIGR01832 kduD: 2-deoxy-D-gluconate 3-dehydrogenase 5 252 4.3E-118 T 14-10-2018 IPR011286 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase GO:0008678|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.127|MetaCyc: PWY-6507|MetaCyc: PWY-7562 TSH58p_21415 34ee72e788fcdaf2f6a955cea7618e71 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_21415 34ee72e788fcdaf2f6a955cea7618e71 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 188 2.4E-4 T 14-10-2018 TSH58p_21415 34ee72e788fcdaf2f6a955cea7618e71 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 249 1.6E-58 T 14-10-2018 TSH58p_21415 34ee72e788fcdaf2f6a955cea7618e71 252 SUPERFAMILY SSF51735 5 251 4.76E-79 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_21415 34ee72e788fcdaf2f6a955cea7618e71 252 Gene3D G3DSA:3.40.50.720 1 252 1.0E-80 T 14-10-2018 TSH58p_21415 34ee72e788fcdaf2f6a955cea7618e71 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.4E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_21415 34ee72e788fcdaf2f6a955cea7618e71 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.4E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_21415 34ee72e788fcdaf2f6a955cea7618e71 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.4E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_21415 34ee72e788fcdaf2f6a955cea7618e71 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.7E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_21415 34ee72e788fcdaf2f6a955cea7618e71 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 2.7E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_21415 34ee72e788fcdaf2f6a955cea7618e71 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 2.7E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_21415 34ee72e788fcdaf2f6a955cea7618e71 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.7E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_21415 34ee72e788fcdaf2f6a955cea7618e71 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.7E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_21415 34ee72e788fcdaf2f6a955cea7618e71 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.7E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_21415 34ee72e788fcdaf2f6a955cea7618e71 252 TIGRFAM TIGR01832 kduD: 2-deoxy-D-gluconate 3-dehydrogenase 5 252 4.3E-118 T 14-10-2018 IPR011286 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase GO:0008678|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.127|MetaCyc: PWY-6507|MetaCyc: PWY-7562 TSH58p_18195 0b92f62fb68b157eff5ad05a8d083fac 888 SUPERFAMILY SSF53756 38 363 6.28E-6 T 14-10-2018 TSH58p_18195 0b92f62fb68b157eff5ad05a8d083fac 888 Pfam PF08241 Methyltransferase domain 469 556 1.8E-14 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TSH58p_18195 0b92f62fb68b157eff5ad05a8d083fac 888 Pfam PF08241 Methyltransferase domain 670 719 1.0E-10 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TSH58p_18195 0b92f62fb68b157eff5ad05a8d083fac 888 SUPERFAMILY SSF53335 454 612 5.32E-21 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_18195 0b92f62fb68b157eff5ad05a8d083fac 888 SUPERFAMILY SSF53335 668 849 2.28E-17 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_18195 0b92f62fb68b157eff5ad05a8d083fac 888 Gene3D G3DSA:3.40.50.150 447 612 3.9E-21 T 14-10-2018 TSH58p_18195 0b92f62fb68b157eff5ad05a8d083fac 888 Pfam PF13524 Glycosyl transferases group 1 272 358 4.2E-23 T 14-10-2018 TSH58p_25160 cf86667e6db5c299366410e5c9e8e3ff 730 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 159 666 1.2E-124 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 TSH58p_25160 cf86667e6db5c299366410e5c9e8e3ff 730 Gene3D G3DSA:3.30.365.10 161 381 2.9E-61 T 14-10-2018 TSH58p_25160 cf86667e6db5c299366410e5c9e8e3ff 730 SMART SM01008 32 138 6.0E-27 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead TSH58p_25160 cf86667e6db5c299366410e5c9e8e3ff 730 Gene3D G3DSA:3.30.365.10 185 277 2.9E-61 T 14-10-2018 TSH58p_25160 cf86667e6db5c299366410e5c9e8e3ff 730 SUPERFAMILY SSF56003 147 726 5.76E-165 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 TSH58p_25160 cf86667e6db5c299366410e5c9e8e3ff 730 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 36 136 8.8E-21 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead TSH58p_25160 cf86667e6db5c299366410e5c9e8e3ff 730 Gene3D G3DSA:3.90.1170.50 3 137 1.0E-25 T 14-10-2018 TSH58p_25160 cf86667e6db5c299366410e5c9e8e3ff 730 SUPERFAMILY SSF54665 6 137 4.84E-32 T 14-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily TSH58p_25160 cf86667e6db5c299366410e5c9e8e3ff 730 Gene3D G3DSA:3.30.365.20 400 728 3.2E-80 T 14-10-2018 TSH58p_11085 44175ae930c6a2a33e6ef95f05f4d6c8 919 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 653 669 1.9E-18 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TSH58p_11085 44175ae930c6a2a33e6ef95f05f4d6c8 919 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 625 641 1.9E-18 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TSH58p_11085 44175ae930c6a2a33e6ef95f05f4d6c8 919 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 512 530 1.9E-18 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TSH58p_11085 44175ae930c6a2a33e6ef95f05f4d6c8 919 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 685 710 1.9E-18 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TSH58p_11085 44175ae930c6a2a33e6ef95f05f4d6c8 919 Pfam PF00690 Cation transporter/ATPase, N-terminus 24 90 3.4E-20 T 14-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 TSH58p_11085 44175ae930c6a2a33e6ef95f05f4d6c8 919 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 619 743 2.4E-34 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TSH58p_11085 44175ae930c6a2a33e6ef95f05f4d6c8 919 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 102 364 2.4E-39 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TSH58p_11085 44175ae930c6a2a33e6ef95f05f4d6c8 919 Gene3D G3DSA:1.20.1110.10 74 908 4.5E-284 T 14-10-2018 TSH58p_11085 44175ae930c6a2a33e6ef95f05f4d6c8 919 SUPERFAMILY SSF81653 133 241 4.97E-29 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 TSH58p_11085 44175ae930c6a2a33e6ef95f05f4d6c8 919 SUPERFAMILY SSF81660 351 558 4.8E-55 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TSH58p_11085 44175ae930c6a2a33e6ef95f05f4d6c8 919 SUPERFAMILY SSF56784 342 757 4.57E-58 T 14-10-2018 IPR036412 HAD-like superfamily TSH58p_11085 44175ae930c6a2a33e6ef95f05f4d6c8 919 SUPERFAMILY SSF81665 22 916 1.83E-123 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 TSH58p_11085 44175ae930c6a2a33e6ef95f05f4d6c8 919 Gene3D G3DSA:3.40.50.1000 341 698 4.5E-284 T 14-10-2018 IPR023214 HAD superfamily TSH58p_11085 44175ae930c6a2a33e6ef95f05f4d6c8 919 SMART SM00831 23 96 8.8E-34 T 14-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 TSH58p_11085 44175ae930c6a2a33e6ef95f05f4d6c8 919 Pfam PF00122 E1-E2 ATPase 131 324 4.6E-52 T 14-10-2018 TSH58p_11085 44175ae930c6a2a33e6ef95f05f4d6c8 919 Pfam PF13246 Cation transport ATPase (P-type) 405 497 1.9E-19 T 14-10-2018 TSH58p_11085 44175ae930c6a2a33e6ef95f05f4d6c8 919 Gene3D G3DSA:3.40.1110.10 354 561 4.5E-284 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TSH58p_11085 44175ae930c6a2a33e6ef95f05f4d6c8 919 Pfam PF08282 haloacid dehalogenase-like hydrolase 639 699 3.4E-6 T 14-10-2018 TSH58p_11085 44175ae930c6a2a33e6ef95f05f4d6c8 919 Pfam PF00689 Cation transporting ATPase, C-terminus 738 909 2.7E-41 T 14-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 TSH58p_11085 44175ae930c6a2a33e6ef95f05f4d6c8 919 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 576 586 2.9E-38 T 14-10-2018 TSH58p_11085 44175ae930c6a2a33e6ef95f05f4d6c8 919 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 677 689 2.9E-38 T 14-10-2018 TSH58p_11085 44175ae930c6a2a33e6ef95f05f4d6c8 919 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 653 672 2.9E-38 T 14-10-2018 TSH58p_11085 44175ae930c6a2a33e6ef95f05f4d6c8 919 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 181 195 2.9E-38 T 14-10-2018 TSH58p_11085 44175ae930c6a2a33e6ef95f05f4d6c8 919 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 554 565 2.9E-38 T 14-10-2018 TSH58p_11085 44175ae930c6a2a33e6ef95f05f4d6c8 919 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 344 358 2.9E-38 T 14-10-2018 TSH58p_11085 44175ae930c6a2a33e6ef95f05f4d6c8 919 Gene3D G3DSA:2.70.150.10 38 246 4.5E-284 T 14-10-2018 TSH58p_11085 44175ae930c6a2a33e6ef95f05f4d6c8 919 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 346 352 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 TSH58p_28010 f1f7b49407c9c3e2dc65581fce2e0aae 348 Gene3D G3DSA:3.30.1330.10 19 166 8.6E-54 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSH58p_28010 f1f7b49407c9c3e2dc65581fce2e0aae 348 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 18 348 1.1E-142 T 14-10-2018 IPR011854 Carbamoyl dehydratase HypE TSH58p_28010 f1f7b49407c9c3e2dc65581fce2e0aae 348 Gene3D G3DSA:3.90.650.10 167 348 8.0E-57 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSH58p_28010 f1f7b49407c9c3e2dc65581fce2e0aae 348 PIRSF PIRSF005644 14 348 5.1E-129 T 14-10-2018 IPR011854 Carbamoyl dehydratase HypE TSH58p_28010 f1f7b49407c9c3e2dc65581fce2e0aae 348 Pfam PF02769 AIR synthase related protein, C-terminal domain 174 324 7.8E-28 T 14-10-2018 IPR010918 PurM-like, C-terminal domain TSH58p_28010 f1f7b49407c9c3e2dc65581fce2e0aae 348 SUPERFAMILY SSF55326 19 165 1.92E-34 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSH58p_28010 f1f7b49407c9c3e2dc65581fce2e0aae 348 Pfam PF00586 AIR synthase related protein, N-terminal domain 53 162 1.0E-16 T 14-10-2018 IPR016188 PurM-like, N-terminal domain TSH58p_28010 f1f7b49407c9c3e2dc65581fce2e0aae 348 SUPERFAMILY SSF56042 171 344 1.94E-46 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSH58p_17155 df196bb34876b192f7bb96de73a9c1d7 574 Gene3D G3DSA:3.10.20.310 149 240 5.3E-14 T 14-10-2018 TSH58p_17155 df196bb34876b192f7bb96de73a9c1d7 574 Pfam PF07244 Surface antigen variable number repeat 165 234 2.6E-6 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 TSH58p_17155 df196bb34876b192f7bb96de73a9c1d7 574 Gene3D G3DSA:2.40.160.50 241 574 1.0E-68 T 14-10-2018 TSH58p_17155 df196bb34876b192f7bb96de73a9c1d7 574 Pfam PF01103 Surface antigen 264 574 4.4E-48 T 14-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 TSH58p_22720 95fd4628d82270e393b6595518398e6b 71 Pfam PF02831 gpW 6 67 2.6E-13 T 14-10-2018 IPR004174 Head-to-tail joining protein W GO:0019058 TSH58p_22720 95fd4628d82270e393b6595518398e6b 71 Gene3D G3DSA:3.30.1580.10 5 65 5.9E-11 T 14-10-2018 IPR036626 Head-to-tail joining protein W superfamily GO:0019058 TSH58p_22720 95fd4628d82270e393b6595518398e6b 71 SUPERFAMILY SSF64210 6 56 1.83E-7 T 14-10-2018 IPR036626 Head-to-tail joining protein W superfamily GO:0019058 TSH58p_26810 dc2c465bf272d50ddb15bd4c293220a9 564 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 366 544 5.9E-29 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_26810 dc2c465bf272d50ddb15bd4c293220a9 564 SUPERFAMILY SSF58104 236 557 2.09E-58 T 14-10-2018 TSH58p_26810 dc2c465bf272d50ddb15bd4c293220a9 564 SMART SM00283 304 558 3.6E-47 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_26810 dc2c465bf272d50ddb15bd4c293220a9 564 SMART SM00304 215 268 1.1E-5 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_26810 dc2c465bf272d50ddb15bd4c293220a9 564 Gene3D G3DSA:1.20.1480.50 173 274 5.0E-10 T 14-10-2018 TSH58p_26810 dc2c465bf272d50ddb15bd4c293220a9 564 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 431 460 6.6E-20 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_26810 dc2c465bf272d50ddb15bd4c293220a9 564 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 6 31 6.6E-20 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_26810 dc2c465bf272d50ddb15bd4c293220a9 564 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 402 429 6.6E-20 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_26810 dc2c465bf272d50ddb15bd4c293220a9 564 Gene3D G3DSA:1.10.287.950 275 564 7.6E-52 T 14-10-2018 TSH58p_02310 4005928de6daa41811a27a4ee5167cc7 232 Pfam PF13545 Crp-like helix-turn-helix domain 152 223 6.9E-13 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_02310 4005928de6daa41811a27a4ee5167cc7 232 SMART SM00100 13 131 2.0E-17 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_02310 4005928de6daa41811a27a4ee5167cc7 232 Pfam PF00027 Cyclic nucleotide-binding domain 32 119 2.1E-16 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_02310 4005928de6daa41811a27a4ee5167cc7 232 SUPERFAMILY SSF46785 148 225 6.74E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_02310 4005928de6daa41811a27a4ee5167cc7 232 SMART SM00419 169 217 6.8E-8 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_02310 4005928de6daa41811a27a4ee5167cc7 232 Gene3D G3DSA:1.10.10.10 147 232 1.7E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_02310 4005928de6daa41811a27a4ee5167cc7 232 Gene3D G3DSA:2.60.120.10 2 146 1.1E-30 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_02310 4005928de6daa41811a27a4ee5167cc7 232 SUPERFAMILY SSF51206 7 142 8.25E-30 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like TSH58p_21065 f5e5da5b9aab03510d25424160b2e41e 344 Pfam PF16220 Domain of unknown function (DUF4880) 23 65 2.9E-12 T 14-10-2018 IPR032623 FecR, N-terminal TSH58p_21065 f5e5da5b9aab03510d25424160b2e41e 344 Gene3D G3DSA:2.60.120.1440 128 258 2.2E-23 T 14-10-2018 TSH58p_21065 f5e5da5b9aab03510d25424160b2e41e 344 Pfam PF04773 FecR protein 138 229 2.5E-21 T 14-10-2018 IPR006860 FecR protein TSH58p_21065 f5e5da5b9aab03510d25424160b2e41e 344 PIRSF PIRSF018266 14 344 1.3E-78 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component TSH58p_06995 c82f07369413d15601ebe9876d585151 257 Gene3D G3DSA:3.90.1340.10 20 85 4.5E-12 T 14-10-2018 IPR037053 Phage tail collar domain superfamily TSH58p_06995 c82f07369413d15601ebe9876d585151 257 Pfam PF07484 Phage Tail Collar Domain 33 89 1.1E-22 T 14-10-2018 IPR011083 Phage tail collar domain TSH58p_06995 c82f07369413d15601ebe9876d585151 257 SUPERFAMILY SSF88874 27 251 1.7E-31 T 14-10-2018 TSH58p_02865 ab486f6fe6e16702391f4d8a87c9e311 478 SUPERFAMILY SSF48179 201 298 6.12E-31 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_02865 ab486f6fe6e16702391f4d8a87c9e311 478 Gene3D G3DSA:3.40.50.720 1 199 5.9E-78 T 14-10-2018 TSH58p_02865 ab486f6fe6e16702391f4d8a87c9e311 478 PIRSF PIRSF000124 1 433 1.2E-136 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 TSH58p_02865 ab486f6fe6e16702391f4d8a87c9e311 478 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 201 293 3.3E-36 T 14-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSH58p_02865 ab486f6fe6e16702391f4d8a87c9e311 478 Gene3D G3DSA:1.20.5.100 200 231 1.9E-16 T 14-10-2018 TSH58p_02865 ab486f6fe6e16702391f4d8a87c9e311 478 SUPERFAMILY SSF52413 304 428 4.19E-36 T 14-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 TSH58p_02865 ab486f6fe6e16702391f4d8a87c9e311 478 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 317 417 7.5E-30 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSH58p_02865 ab486f6fe6e16702391f4d8a87c9e311 478 PIRSF PIRSF500134 1 436 1.2E-174 T 14-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 TSH58p_02865 ab486f6fe6e16702391f4d8a87c9e311 478 SMART SM00984 317 418 6.6E-47 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSH58p_02865 ab486f6fe6e16702391f4d8a87c9e311 478 SUPERFAMILY SSF51735 1 190 5.97E-53 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_02865 ab486f6fe6e16702391f4d8a87c9e311 478 Gene3D G3DSA:3.40.50.720 232 451 1.8E-73 T 14-10-2018 TSH58p_02865 ab486f6fe6e16702391f4d8a87c9e311 478 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 414 4.9E-137 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 TSH58p_02865 ab486f6fe6e16702391f4d8a87c9e311 478 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 183 1.2E-64 T 14-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSH58p_25145 8b09e99c13df9e15492fc8c7e31de5ca 312 SUPERFAMILY SSF53850 89 294 1.55E-34 T 14-10-2018 TSH58p_25145 8b09e99c13df9e15492fc8c7e31de5ca 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.9E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_25145 8b09e99c13df9e15492fc8c7e31de5ca 312 SUPERFAMILY SSF46785 1 86 1.45E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_25145 8b09e99c13df9e15492fc8c7e31de5ca 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.0E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_25145 8b09e99c13df9e15492fc8c7e31de5ca 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.0E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_25145 8b09e99c13df9e15492fc8c7e31de5ca 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.0E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_25145 8b09e99c13df9e15492fc8c7e31de5ca 312 Gene3D G3DSA:3.40.190.10 164 264 3.0E-34 T 14-10-2018 TSH58p_25145 8b09e99c13df9e15492fc8c7e31de5ca 312 Pfam PF03466 LysR substrate binding domain 87 289 1.5E-35 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_25145 8b09e99c13df9e15492fc8c7e31de5ca 312 Gene3D G3DSA:3.40.190.10 91 278 3.0E-34 T 14-10-2018 TSH58p_25145 8b09e99c13df9e15492fc8c7e31de5ca 312 Gene3D G3DSA:1.10.10.10 1 86 5.3E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_15235 6d2094ed5d9051bc028f33abf78cece1 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15235 6d2094ed5d9051bc028f33abf78cece1 132 Pfam PF00410 Ribosomal protein S8 5 132 2.1E-47 T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15235 6d2094ed5d9051bc028f33abf78cece1 132 Gene3D G3DSA:3.30.1370.30 2 74 9.4E-23 T 14-10-2018 TSH58p_15235 6d2094ed5d9051bc028f33abf78cece1 132 Gene3D G3DSA:3.30.1490.10 75 131 2.7E-25 T 14-10-2018 TSH58p_15235 6d2094ed5d9051bc028f33abf78cece1 132 SUPERFAMILY SSF56047 3 132 1.31E-44 T 14-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15235 6d2094ed5d9051bc028f33abf78cece1 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 31.213 T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_28820 d44ecbb5f0e2de8c40c2ac50c6f5d4f6 318 Gene3D G3DSA:1.10.10.10 4 88 3.5E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_28820 d44ecbb5f0e2de8c40c2ac50c6f5d4f6 318 Pfam PF03466 LysR substrate binding domain 93 298 4.0E-48 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_28820 d44ecbb5f0e2de8c40c2ac50c6f5d4f6 318 Gene3D G3DSA:3.40.190.10 96 292 1.0E-66 T 14-10-2018 TSH58p_28820 d44ecbb5f0e2de8c40c2ac50c6f5d4f6 318 SUPERFAMILY SSF46785 6 91 1.12E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_28820 d44ecbb5f0e2de8c40c2ac50c6f5d4f6 318 SUPERFAMILY SSF53850 92 300 1.18E-42 T 14-10-2018 TSH58p_28820 d44ecbb5f0e2de8c40c2ac50c6f5d4f6 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 7.8E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_28820 d44ecbb5f0e2de8c40c2ac50c6f5d4f6 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 7.8E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_28820 d44ecbb5f0e2de8c40c2ac50c6f5d4f6 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 7.8E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_28820 d44ecbb5f0e2de8c40c2ac50c6f5d4f6 318 Gene3D G3DSA:3.40.190.10 165 269 1.0E-66 T 14-10-2018 TSH58p_28820 d44ecbb5f0e2de8c40c2ac50c6f5d4f6 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 1.1E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_14310 fc5dec6a8c1619315588fdc03e75d9d4 302 Gene3D G3DSA:3.90.78.10 217 301 4.5E-32 T 14-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSH58p_14310 fc5dec6a8c1619315588fdc03e75d9d4 302 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 200 299 2.7E-29 T 14-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSH58p_14310 fc5dec6a8c1619315588fdc03e75d9d4 302 SUPERFAMILY SSF56194 196 301 1.28E-36 T 14-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSH58p_14310 fc5dec6a8c1619315588fdc03e75d9d4 302 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 302 94.042 T 14-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSH58p_14310 fc5dec6a8c1619315588fdc03e75d9d4 302 SUPERFAMILY SSF56176 24 208 1.71E-41 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TSH58p_14310 fc5dec6a8c1619315588fdc03e75d9d4 302 Gene3D G3DSA:3.30.43.10 6 87 6.3E-22 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 TSH58p_14310 fc5dec6a8c1619315588fdc03e75d9d4 302 Pfam PF01565 FAD binding domain 38 164 8.0E-17 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TSH58p_14310 fc5dec6a8c1619315588fdc03e75d9d4 302 Gene3D G3DSA:3.30.465.10 92 216 2.0E-30 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TSH58p_14310 fc5dec6a8c1619315588fdc03e75d9d4 302 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 25 299 2.2E-54 T 14-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSH58p_18120 8af35d0a8c86c262d20d9570f7813635 270 Pfam PF00696 Amino acid kinase family 39 218 1.3E-20 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TSH58p_18120 8af35d0a8c86c262d20d9570f7813635 270 SUPERFAMILY SSF53633 36 268 1.96E-28 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSH58p_18120 8af35d0a8c86c262d20d9570f7813635 270 PIRSF PIRSF039097 1 270 4.5E-118 T 14-10-2018 IPR030669 Molybdenum storage protein subunit alpha/beta GO:0005737|GO:0030151 TSH58p_18120 8af35d0a8c86c262d20d9570f7813635 270 Gene3D G3DSA:3.40.1160.10 1 270 2.6E-75 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSH58p_23995 94deac4d440ce9c73fe447c80b9e7bf1 261 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 5 261 2.7E-106 T 14-10-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 TSH58p_23995 94deac4d440ce9c73fe447c80b9e7bf1 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 6.1E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_23995 94deac4d440ce9c73fe447c80b9e7bf1 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 6.1E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_23995 94deac4d440ce9c73fe447c80b9e7bf1 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 6.1E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_23995 94deac4d440ce9c73fe447c80b9e7bf1 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_23995 94deac4d440ce9c73fe447c80b9e7bf1 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 259 5.1E-58 T 14-10-2018 TSH58p_23995 94deac4d440ce9c73fe447c80b9e7bf1 261 Gene3D G3DSA:3.40.50.720 1 261 1.8E-79 T 14-10-2018 TSH58p_23995 94deac4d440ce9c73fe447c80b9e7bf1 261 SUPERFAMILY SSF51735 5 260 1.88E-77 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_23995 94deac4d440ce9c73fe447c80b9e7bf1 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.1E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_23995 94deac4d440ce9c73fe447c80b9e7bf1 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.1E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_23995 94deac4d440ce9c73fe447c80b9e7bf1 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.1E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_23995 94deac4d440ce9c73fe447c80b9e7bf1 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.1E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_23995 94deac4d440ce9c73fe447c80b9e7bf1 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 1.1E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_23995 94deac4d440ce9c73fe447c80b9e7bf1 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.1E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_01350 7df2119c40bd5047a2e4f638509d693c 133 Gene3D G3DSA:3.10.129.10 6 128 1.0E-27 T 14-10-2018 TSH58p_01350 7df2119c40bd5047a2e4f638509d693c 133 Pfam PF01575 MaoC like domain 13 102 4.0E-17 T 14-10-2018 IPR002539 MaoC-like dehydratase domain TSH58p_01350 7df2119c40bd5047a2e4f638509d693c 133 SUPERFAMILY SSF54637 10 124 2.7E-26 T 14-10-2018 IPR029069 HotDog domain superfamily TSH58p_01340 aff0996c1f925ab774fd78b9cc3f5df4 381 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 279 292 1.5E-8 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_01340 aff0996c1f925ab774fd78b9cc3f5df4 381 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 51 67 1.5E-8 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_01340 aff0996c1f925ab774fd78b9cc3f5df4 381 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 29 45 1.5E-8 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_01340 aff0996c1f925ab774fd78b9cc3f5df4 381 SUPERFAMILY SSF53822 30 376 5.57E-74 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_01340 aff0996c1f925ab774fd78b9cc3f5df4 381 Gene3D G3DSA:3.40.50.2300 30 349 2.9E-68 T 14-10-2018 TSH58p_01340 aff0996c1f925ab774fd78b9cc3f5df4 381 Gene3D G3DSA:3.40.50.2300 147 272 2.9E-68 T 14-10-2018 TSH58p_01340 aff0996c1f925ab774fd78b9cc3f5df4 381 Pfam PF13458 Periplasmic binding protein 29 370 1.6E-62 T 14-10-2018 IPR028081 Leucine-binding protein domain TSH58p_31680 3716c74f17a4597291bb5fbb54ab1708 692 SUPERFAMILY SSF54292 567 679 2.23E-16 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TSH58p_31680 3716c74f17a4597291bb5fbb54ab1708 692 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 638 646 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 TSH58p_31680 3716c74f17a4597291bb5fbb54ab1708 692 Pfam PF00970 Oxidoreductase FAD-binding domain 338 433 8.9E-10 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 TSH58p_31680 3716c74f17a4597291bb5fbb54ab1708 692 SUPERFAMILY SSF63380 333 433 7.17E-28 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TSH58p_31680 3716c74f17a4597291bb5fbb54ab1708 692 Gene3D G3DSA:3.10.20.30 596 682 3.7E-15 T 14-10-2018 IPR012675 Beta-grasp domain superfamily TSH58p_31680 3716c74f17a4597291bb5fbb54ab1708 692 Pfam PF00175 Oxidoreductase NAD-binding domain 445 555 3.0E-11 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 TSH58p_31680 3716c74f17a4597291bb5fbb54ab1708 692 SUPERFAMILY SSF52343 439 578 8.91E-31 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TSH58p_31680 3716c74f17a4597291bb5fbb54ab1708 692 SUPERFAMILY SSF50475 175 278 2.98E-8 T 14-10-2018 TSH58p_31680 3716c74f17a4597291bb5fbb54ab1708 692 Gene3D G3DSA:3.40.50.80 437 581 5.8E-30 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TSH58p_31680 3716c74f17a4597291bb5fbb54ab1708 692 Gene3D G3DSA:2.30.110.10 169 293 2.5E-12 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TSH58p_31680 3716c74f17a4597291bb5fbb54ab1708 692 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 618 677 1.2E-8 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 TSH58p_31680 3716c74f17a4597291bb5fbb54ab1708 692 Gene3D G3DSA:2.40.30.10 333 434 2.3E-30 T 14-10-2018 TSH58p_31680 3716c74f17a4597291bb5fbb54ab1708 692 PRINTS PR00410 Phenol hydroxylase reductase family signature 428 437 3.7E-9 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TSH58p_31680 3716c74f17a4597291bb5fbb54ab1708 692 PRINTS PR00410 Phenol hydroxylase reductase family signature 543 551 3.7E-9 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TSH58p_31680 3716c74f17a4597291bb5fbb54ab1708 692 PRINTS PR00410 Phenol hydroxylase reductase family signature 366 378 3.7E-9 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TSH58p_31680 3716c74f17a4597291bb5fbb54ab1708 692 PRINTS PR00410 Phenol hydroxylase reductase family signature 444 463 3.7E-9 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TSH58p_31680 3716c74f17a4597291bb5fbb54ab1708 692 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 175 270 1.3E-11 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 TSH58p_14990 c919429f0b740f3882784929a0c666cd 274 Gene3D G3DSA:3.30.70.1020 111 187 5.1E-46 T 14-10-2018 TSH58p_14990 c919429f0b740f3882784929a0c666cd 274 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 30 268 1.1E-49 T 14-10-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 TSH58p_14990 c919429f0b740f3882784929a0c666cd 274 Gene3D G3DSA:3.40.50.1000 34 251 5.1E-46 T 14-10-2018 IPR023214 HAD superfamily TSH58p_14990 c919429f0b740f3882784929a0c666cd 274 Pfam PF02358 Trehalose-phosphatase 35 257 2.3E-48 T 14-10-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 TSH58p_14990 c919429f0b740f3882784929a0c666cd 274 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 34 229 7.2E-18 T 14-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 TSH58p_14990 c919429f0b740f3882784929a0c666cd 274 SUPERFAMILY SSF56784 33 268 3.22E-36 T 14-10-2018 IPR036412 HAD-like superfamily TSH58p_15680 acc6a622484c184f0346938a6e196415 415 SUPERFAMILY SSF55021 338 410 2.68E-14 T 14-10-2018 TSH58p_15680 acc6a622484c184f0346938a6e196415 415 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 200 222 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TSH58p_15680 acc6a622484c184f0346938a6e196415 415 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 13 326 6.7E-33 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 TSH58p_15680 acc6a622484c184f0346938a6e196415 415 Gene3D G3DSA:3.40.50.720 14 312 1.7E-104 T 14-10-2018 TSH58p_15680 acc6a622484c184f0346938a6e196415 415 SUPERFAMILY SSF51735 108 295 1.7E-57 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_15680 acc6a622484c184f0346938a6e196415 415 Gene3D G3DSA:3.40.50.720 109 297 1.7E-104 T 14-10-2018 TSH58p_15680 acc6a622484c184f0346938a6e196415 415 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 154 181 - T 14-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 TSH58p_15680 acc6a622484c184f0346938a6e196415 415 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 118 294 3.7E-52 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TSH58p_15680 acc6a622484c184f0346938a6e196415 415 Gene3D G3DSA:3.30.70.260 328 410 1.4E-27 T 14-10-2018 TSH58p_15680 acc6a622484c184f0346938a6e196415 415 SUPERFAMILY SSF52283 8 133 8.51E-45 T 14-10-2018 TSH58p_27000 10142cd094d242c6ca49ecccd418949e 633 Gene3D G3DSA:3.40.50.300 9 190 2.2E-44 T 14-10-2018 TSH58p_27000 10142cd094d242c6ca49ecccd418949e 633 Pfam PF02421 Ferrous iron transport protein B 11 171 4.5E-55 T 14-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 TSH58p_27000 10142cd094d242c6ca49ecccd418949e 633 Pfam PF07664 Ferrous iron transport protein B C terminus 415 467 5.4E-17 T 14-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 TSH58p_27000 10142cd094d242c6ca49ecccd418949e 633 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 33 51 2.4E-7 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 TSH58p_27000 10142cd094d242c6ca49ecccd418949e 633 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 12 32 2.4E-7 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 TSH58p_27000 10142cd094d242c6ca49ecccd418949e 633 SUPERFAMILY SSF52540 10 174 4.94E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_27000 10142cd094d242c6ca49ecccd418949e 633 Pfam PF07670 Nucleoside recognition 472 604 5.0E-26 T 14-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 TSH58p_27000 10142cd094d242c6ca49ecccd418949e 633 Pfam PF07670 Nucleoside recognition 304 391 3.7E-11 T 14-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 TSH58p_27285 e73527e96bb9b5f249ebefb060d76213 419 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 34 57 - T 14-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 TSH58p_27285 e73527e96bb9b5f249ebefb060d76213 419 Pfam PF05193 Peptidase M16 inactive domain 177 337 1.0E-35 T 14-10-2018 IPR007863 Peptidase M16, C-terminal TSH58p_27285 e73527e96bb9b5f249ebefb060d76213 419 Gene3D G3DSA:3.30.830.10 3 216 7.6E-66 T 14-10-2018 TSH58p_27285 e73527e96bb9b5f249ebefb060d76213 419 SUPERFAMILY SSF63411 224 410 1.36E-43 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TSH58p_27285 e73527e96bb9b5f249ebefb060d76213 419 Gene3D G3DSA:3.30.830.10 221 412 3.4E-54 T 14-10-2018 TSH58p_27285 e73527e96bb9b5f249ebefb060d76213 419 SUPERFAMILY SSF63411 2 205 2.93E-53 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TSH58p_27285 e73527e96bb9b5f249ebefb060d76213 419 Pfam PF00675 Insulinase (Peptidase family M16) 13 161 5.0E-40 T 14-10-2018 IPR011765 Peptidase M16, N-terminal TSH58p_06495 a222f5323ab73081e9fafd8ce0cd0548 346 Gene3D G3DSA:3.30.420.40 155 320 9.1E-134 T 14-10-2018 TSH58p_06495 a222f5323ab73081e9fafd8ce0cd0548 346 Gene3D G3DSA:3.90.640.10 187 262 9.1E-134 T 14-10-2018 TSH58p_06495 a222f5323ab73081e9fafd8ce0cd0548 346 SUPERFAMILY SSF53067 10 149 3.53E-40 T 14-10-2018 TSH58p_06495 a222f5323ab73081e9fafd8ce0cd0548 346 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 10 339 8.0E-159 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 TSH58p_06495 a222f5323ab73081e9fafd8ce0cd0548 346 SUPERFAMILY SSF53067 150 332 1.16E-47 T 14-10-2018 TSH58p_06495 a222f5323ab73081e9fafd8ce0cd0548 346 Pfam PF06723 MreB/Mbl protein 11 339 2.0E-152 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 TSH58p_06495 a222f5323ab73081e9fafd8ce0cd0548 346 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 70 93 7.3E-63 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 TSH58p_06495 a222f5323ab73081e9fafd8ce0cd0548 346 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 133 152 7.3E-63 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 TSH58p_06495 a222f5323ab73081e9fafd8ce0cd0548 346 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 50 68 7.3E-63 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 TSH58p_06495 a222f5323ab73081e9fafd8ce0cd0548 346 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 188 208 7.3E-63 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 TSH58p_06495 a222f5323ab73081e9fafd8ce0cd0548 346 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 303 329 7.3E-63 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 TSH58p_06495 a222f5323ab73081e9fafd8ce0cd0548 346 Gene3D G3DSA:3.30.420.40 13 330 9.1E-134 T 14-10-2018 TSH58p_14470 479371d0621e4369e108aa271b8dc268 292 SUPERFAMILY SSF52096 20 226 1.99E-32 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_14470 479371d0621e4369e108aa271b8dc268 292 Gene3D G3DSA:3.40.1750.20 128 194 6.8E-51 T 14-10-2018 TSH58p_14470 479371d0621e4369e108aa271b8dc268 292 Pfam PF01343 Peptidase family S49 89 230 5.5E-25 T 14-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 TSH58p_14470 479371d0621e4369e108aa271b8dc268 292 Gene3D G3DSA:3.90.226.10 24 229 6.8E-51 T 14-10-2018 TSH58p_14365 a0d81c15c60d3ba3f64741a3b752f3f1 336 SUPERFAMILY SSF81799 126 225 1.02E-35 T 14-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 TSH58p_14365 a0d81c15c60d3ba3f64741a3b752f3f1 336 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 17 322 1.3E-96 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 TSH58p_14365 a0d81c15c60d3ba3f64741a3b752f3f1 336 Gene3D G3DSA:3.40.50.150 19 321 9.0E-105 T 14-10-2018 TSH58p_14365 a0d81c15c60d3ba3f64741a3b752f3f1 336 SUPERFAMILY SSF53335 18 322 1.4E-50 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_14365 a0d81c15c60d3ba3f64741a3b752f3f1 336 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 19 323 38.536 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 TSH58p_14365 a0d81c15c60d3ba3f64741a3b752f3f1 336 Pfam PF01795 MraW methylase family 17 322 2.6E-102 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 TSH58p_14365 a0d81c15c60d3ba3f64741a3b752f3f1 336 PIRSF PIRSF004486 13 324 2.0E-103 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 TSH58p_14365 a0d81c15c60d3ba3f64741a3b752f3f1 336 Gene3D G3DSA:1.10.150.170 124 226 9.0E-105 T 14-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 TSH58p_11880 939ec9c03244a98581019aa4ae0c9f78 660 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 450 629 4.9E-34 T 14-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 TSH58p_11880 939ec9c03244a98581019aa4ae0c9f78 660 Gene3D G3DSA:3.30.450.20 202 355 8.6E-8 T 14-10-2018 TSH58p_11880 939ec9c03244a98581019aa4ae0c9f78 660 SMART SM00044 399 613 2.4E-18 T 14-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 TSH58p_11880 939ec9c03244a98581019aa4ae0c9f78 660 SUPERFAMILY SSF55073 448 639 8.79E-59 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_11880 939ec9c03244a98581019aa4ae0c9f78 660 Gene3D G3DSA:3.30.70.1230 443 645 3.6E-63 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_12640 4fd28a245f65fea96e64ed61bdaec876 896 Gene3D G3DSA:3.30.499.10 379 593 1.9E-97 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 TSH58p_12640 4fd28a245f65fea96e64ed61bdaec876 896 Gene3D G3DSA:1.10.1440.20 594 654 4.1E-16 T 14-10-2018 TSH58p_12640 4fd28a245f65fea96e64ed61bdaec876 896 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 22 894 0.0 T 14-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 TSH58p_12640 4fd28a245f65fea96e64ed61bdaec876 896 Pfam PF00330 Aconitase family (aconitate hydratase) 79 565 2.4E-187 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_12640 4fd28a245f65fea96e64ed61bdaec876 896 ProSitePatterns PS01244 Aconitase family signature 2. 496 509 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 TSH58p_12640 4fd28a245f65fea96e64ed61bdaec876 896 SUPERFAMILY SSF53732 8 629 7.72E-230 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 TSH58p_12640 4fd28a245f65fea96e64ed61bdaec876 896 PRINTS PR00415 Aconitase family signature 496 509 3.0E-44 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_12640 4fd28a245f65fea96e64ed61bdaec876 896 PRINTS PR00415 Aconitase family signature 284 297 3.0E-44 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_12640 4fd28a245f65fea96e64ed61bdaec876 896 PRINTS PR00415 Aconitase family signature 378 392 3.0E-44 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_12640 4fd28a245f65fea96e64ed61bdaec876 896 PRINTS PR00415 Aconitase family signature 298 311 3.0E-44 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_12640 4fd28a245f65fea96e64ed61bdaec876 896 PRINTS PR00415 Aconitase family signature 174 182 3.0E-44 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_12640 4fd28a245f65fea96e64ed61bdaec876 896 PRINTS PR00415 Aconitase family signature 208 221 3.0E-44 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_12640 4fd28a245f65fea96e64ed61bdaec876 896 PRINTS PR00415 Aconitase family signature 222 237 3.0E-44 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_12640 4fd28a245f65fea96e64ed61bdaec876 896 PRINTS PR00415 Aconitase family signature 434 445 3.0E-44 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_12640 4fd28a245f65fea96e64ed61bdaec876 896 PRINTS PR00415 Aconitase family signature 150 163 3.0E-44 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_12640 4fd28a245f65fea96e64ed61bdaec876 896 ProSitePatterns PS00450 Aconitase family signature 1. 430 446 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 TSH58p_12640 4fd28a245f65fea96e64ed61bdaec876 896 SUPERFAMILY SSF52016 633 894 3.34E-90 T 14-10-2018 TSH58p_12640 4fd28a245f65fea96e64ed61bdaec876 896 Pfam PF00694 Aconitase C-terminal domain 696 822 2.1E-46 T 14-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 TSH58p_12640 4fd28a245f65fea96e64ed61bdaec876 896 Gene3D G3DSA:3.30.499.20 9 378 3.2E-162 T 14-10-2018 TSH58p_12640 4fd28a245f65fea96e64ed61bdaec876 896 Gene3D G3DSA:3.20.19.10 657 896 3.4E-106 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 TSH58p_16775 dc6bb185e440d3e1787029c86d1742ed 159 Pfam PF01724 Domain of unknown function DUF29 7 145 5.8E-33 T 14-10-2018 IPR002636 Protein from unkown function DUF29 TSH58p_16775 dc6bb185e440d3e1787029c86d1742ed 159 Gene3D G3DSA:1.20.1220.20 2 157 4.6E-43 T 14-10-2018 TSH58p_15325 000bf96c90d4b2d95529cd029b1e17d9 629 Pfam PF00664 ABC transporter transmembrane region 68 331 1.1E-48 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TSH58p_15325 000bf96c90d4b2d95529cd029b1e17d9 629 Gene3D G3DSA:3.40.50.300 371 624 9.4E-93 T 14-10-2018 TSH58p_15325 000bf96c90d4b2d95529cd029b1e17d9 629 TIGRFAM TIGR02204 MsbA_rel: ABC transporter, permease/ATP-binding protein 43 617 6.9E-266 T 14-10-2018 IPR011918 ABC transporter, ATP-binding/permease protein TSH58p_15325 000bf96c90d4b2d95529cd029b1e17d9 629 SUPERFAMILY SSF52540 372 617 9.85E-90 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_15325 000bf96c90d4b2d95529cd029b1e17d9 629 ProSitePatterns PS00211 ABC transporters family signature. 518 532 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_15325 000bf96c90d4b2d95529cd029b1e17d9 629 SUPERFAMILY SSF90123 48 365 1.18E-77 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_15325 000bf96c90d4b2d95529cd029b1e17d9 629 Pfam PF00005 ABC transporter 397 546 1.6E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_15325 000bf96c90d4b2d95529cd029b1e17d9 629 Gene3D G3DSA:1.20.1560.10 39 360 4.6E-84 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_15325 000bf96c90d4b2d95529cd029b1e17d9 629 SMART SM00382 406 592 9.2E-21 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_21725 9972fc93e5c361cbeea0a850ff539992 386 Gene3D G3DSA:2.40.50.100 87 232 1.9E-60 T 14-10-2018 TSH58p_21725 9972fc93e5c361cbeea0a850ff539992 386 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 73 302 6.7E-33 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain TSH58p_21725 9972fc93e5c361cbeea0a850ff539992 386 Gene3D G3DSA:2.40.420.20 73 366 1.9E-60 T 14-10-2018 TSH58p_21725 9972fc93e5c361cbeea0a850ff539992 386 Gene3D G3DSA:2.40.30.170 76 309 1.9E-60 T 14-10-2018 TSH58p_21725 9972fc93e5c361cbeea0a850ff539992 386 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 70 383 7.8E-70 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 TSH58p_21725 9972fc93e5c361cbeea0a850ff539992 386 Gene3D G3DSA:1.10.287.470 121 198 1.9E-60 T 14-10-2018 TSH58p_21725 9972fc93e5c361cbeea0a850ff539992 386 SUPERFAMILY SSF111369 77 302 5.1E-27 T 14-10-2018 TSH58p_08120 82e00a5b76a69720f6c09bcee089f30d 313 SUPERFAMILY SSF53474 8 309 1.32E-40 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_08120 82e00a5b76a69720f6c09bcee089f30d 313 Gene3D G3DSA:3.40.50.1820 10 311 1.1E-51 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_08120 82e00a5b76a69720f6c09bcee089f30d 313 Pfam PF12146 Serine aminopeptidase, S33 36 294 2.4E-41 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 TSH58p_01470 ffa5dc33f1110c7b7ebfb2ecd2c8ad7f 287 Gene3D G3DSA:3.40.50.1980 190 285 7.6E-7 T 14-10-2018 TSH58p_01470 ffa5dc33f1110c7b7ebfb2ecd2c8ad7f 287 Pfam PF01297 Zinc-uptake complex component A periplasmic 129 279 2.0E-14 T 14-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 TSH58p_01470 ffa5dc33f1110c7b7ebfb2ecd2c8ad7f 287 SUPERFAMILY SSF53807 68 279 2.16E-27 T 14-10-2018 TSH58p_22435 73102f2ebd5cf6e55d6dd51989907dfb 439 Pfam PF01476 LysM domain 97 140 2.1E-10 T 14-10-2018 IPR018392 LysM domain TSH58p_22435 73102f2ebd5cf6e55d6dd51989907dfb 439 Pfam PF01476 LysM domain 50 92 1.2E-11 T 14-10-2018 IPR018392 LysM domain TSH58p_22435 73102f2ebd5cf6e55d6dd51989907dfb 439 Pfam PF01551 Peptidase family M23 324 418 7.4E-30 T 14-10-2018 IPR016047 Peptidase M23 TSH58p_22435 73102f2ebd5cf6e55d6dd51989907dfb 439 SMART SM00257 48 92 3.5E-11 T 14-10-2018 IPR018392 LysM domain TSH58p_22435 73102f2ebd5cf6e55d6dd51989907dfb 439 SMART SM00257 96 140 1.1E-9 T 14-10-2018 IPR018392 LysM domain TSH58p_22435 73102f2ebd5cf6e55d6dd51989907dfb 439 SUPERFAMILY SSF54106 50 93 1.96E-8 T 14-10-2018 TSH58p_22435 73102f2ebd5cf6e55d6dd51989907dfb 439 SUPERFAMILY SSF51261 280 419 7.85E-46 T 14-10-2018 IPR011055 Duplicated hybrid motif TSH58p_22435 73102f2ebd5cf6e55d6dd51989907dfb 439 Gene3D G3DSA:3.10.350.10 96 140 8.7E-12 T 14-10-2018 IPR036779 LysM domain superfamily TSH58p_22435 73102f2ebd5cf6e55d6dd51989907dfb 439 SUPERFAMILY SSF54106 96 140 6.15E-9 T 14-10-2018 TSH58p_22435 73102f2ebd5cf6e55d6dd51989907dfb 439 Gene3D G3DSA:3.10.350.10 37 95 7.1E-12 T 14-10-2018 IPR036779 LysM domain superfamily TSH58p_22435 73102f2ebd5cf6e55d6dd51989907dfb 439 Gene3D G3DSA:2.70.70.10 289 422 2.0E-38 T 14-10-2018 IPR011055 Duplicated hybrid motif TSH58p_28870 3245f41ad0f4ec9b68153fb1c27fab5f 623 Gene3D G3DSA:3.40.50.300 206 441 4.4E-16 T 14-10-2018 TSH58p_28870 3245f41ad0f4ec9b68153fb1c27fab5f 623 Gene3D G3DSA:3.40.50.300 3 178 2.8E-11 T 14-10-2018 TSH58p_28870 3245f41ad0f4ec9b68153fb1c27fab5f 623 SUPERFAMILY SSF52540 17 403 5.48E-15 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_28870 3245f41ad0f4ec9b68153fb1c27fab5f 623 Pfam PF04851 Type III restriction enzyme, res subunit 12 170 3.7E-6 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TSH58p_10680 67b70b942d29a584fbf45a585779fe48 402 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 20 399 1.1E-127 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TSH58p_10680 67b70b942d29a584fbf45a585779fe48 402 TIGRFAM TIGR01325 O_suc_HS_sulf: O-succinylhomoserine sulfhydrylase 20 399 1.4E-164 T 14-10-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 TSH58p_10680 67b70b942d29a584fbf45a585779fe48 402 Hamap MF_02056 O-succinylhomoserine sulfhydrylase [metZ]. 18 400 51.214 T 14-10-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 TSH58p_10680 67b70b942d29a584fbf45a585779fe48 402 Gene3D G3DSA:3.90.1150.10 268 402 3.4E-49 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_10680 67b70b942d29a584fbf45a585779fe48 402 Gene3D G3DSA:3.40.640.10 13 265 3.2E-79 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_10680 67b70b942d29a584fbf45a585779fe48 402 SUPERFAMILY SSF53383 37 400 8.87E-110 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_10680 67b70b942d29a584fbf45a585779fe48 402 PIRSF PIRSF001434 3 402 3.7E-121 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TSH58p_16995 ea057921b0f431cd656bddc2c989c8ef 432 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 22 429 5.7E-139 T 14-10-2018 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 TSH58p_16995 ea057921b0f431cd656bddc2c989c8ef 432 Gene3D G3DSA:3.90.1580.10 344 432 1.4E-8 T 14-10-2018 TSH58p_16995 ea057921b0f431cd656bddc2c989c8ef 432 Gene3D G3DSA:3.90.1580.10 183 343 2.8E-26 T 14-10-2018 TSH58p_16995 ea057921b0f431cd656bddc2c989c8ef 432 SUPERFAMILY SSF109854 15 157 2.11E-5 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TSH58p_16995 ea057921b0f431cd656bddc2c989c8ef 432 Pfam PF03781 Sulfatase-modifying factor enzyme 1 352 429 1.8E-7 T 14-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 TSH58p_16995 ea057921b0f431cd656bddc2c989c8ef 432 Pfam PF03781 Sulfatase-modifying factor enzyme 1 193 341 1.4E-23 T 14-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 TSH58p_16995 ea057921b0f431cd656bddc2c989c8ef 432 SUPERFAMILY SSF56436 191 431 3.06E-61 T 14-10-2018 IPR016187 C-type lectin fold TSH58p_16995 ea057921b0f431cd656bddc2c989c8ef 432 Pfam PF12867 DinB superfamily 25 159 9.1E-11 T 14-10-2018 IPR024775 DinB-like domain TSH58p_12705 0fb9e1ceceb5dd712dcbd4803281cdd3 300 Gene3D G3DSA:2.60.120.10 156 255 7.0E-70 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_12705 0fb9e1ceceb5dd712dcbd4803281cdd3 300 SUPERFAMILY SSF51182 17 297 2.38E-83 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_12705 0fb9e1ceceb5dd712dcbd4803281cdd3 300 PIRSF PIRSF006232 14 293 1.5E-84 T 14-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 TSH58p_12705 0fb9e1ceceb5dd712dcbd4803281cdd3 300 Gene3D G3DSA:2.60.120.10 28 281 7.0E-70 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_12705 0fb9e1ceceb5dd712dcbd4803281cdd3 300 Pfam PF05726 Pirin C-terminal cupin domain 187 286 4.8E-27 T 14-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 TSH58p_12705 0fb9e1ceceb5dd712dcbd4803281cdd3 300 Pfam PF02678 Pirin 29 134 9.5E-32 T 14-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 TSH58p_02065 62efc648d9a470aa5697b1eab3ccbc4a 67 Pfam PF11127 Protein of unknown function (DUF2892) 2 62 2.5E-16 T 14-10-2018 IPR021309 Protein of unknown function DUF2892 TSH58p_11495 05a7932e6e20a6041c53dba789b32c21 185 SUPERFAMILY SSF50324 4 173 2.22E-67 T 14-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TSH58p_11495 05a7932e6e20a6041c53dba789b32c21 185 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 174 36.942 T 14-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TSH58p_11495 05a7932e6e20a6041c53dba789b32c21 185 Pfam PF00719 Inorganic pyrophosphatase 18 172 2.6E-56 T 14-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TSH58p_11495 05a7932e6e20a6041c53dba789b32c21 185 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 14-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TSH58p_11495 05a7932e6e20a6041c53dba789b32c21 185 Gene3D G3DSA:3.90.80.10 1 175 4.1E-69 T 14-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TSH58p_02245 230fe0ccb1fb40957d95f826754889a9 307 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_02245 230fe0ccb1fb40957d95f826754889a9 307 Gene3D G3DSA:3.40.50.300 1 305 8.4E-92 T 14-10-2018 TSH58p_02245 230fe0ccb1fb40957d95f826754889a9 307 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 207 295 6.4E-23 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_02245 230fe0ccb1fb40957d95f826754889a9 307 SMART SM00382 7 206 9.1E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_02245 230fe0ccb1fb40957d95f826754889a9 307 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 208 269 3.6E-19 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_02245 230fe0ccb1fb40957d95f826754889a9 307 SUPERFAMILY SSF52540 10 269 1.63E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_02245 230fe0ccb1fb40957d95f826754889a9 307 Pfam PF00005 ABC transporter 1 156 1.2E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_08385 4ef687bb33e19ca7181ba23f9e8b7a79 372 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 41 361 1.4E-71 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 TSH58p_08385 4ef687bb33e19ca7181ba23f9e8b7a79 372 SUPERFAMILY SSF111369 57 283 1.44E-23 T 14-10-2018 TSH58p_08385 4ef687bb33e19ca7181ba23f9e8b7a79 372 Gene3D G3DSA:2.40.30.170 50 287 2.2E-67 T 14-10-2018 TSH58p_08385 4ef687bb33e19ca7181ba23f9e8b7a79 372 Gene3D G3DSA:2.40.420.20 43 360 2.2E-67 T 14-10-2018 TSH58p_08385 4ef687bb33e19ca7181ba23f9e8b7a79 372 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 63 278 5.4E-21 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain TSH58p_08385 4ef687bb33e19ca7181ba23f9e8b7a79 372 Gene3D G3DSA:1.10.287.470 99 171 2.2E-67 T 14-10-2018 TSH58p_08385 4ef687bb33e19ca7181ba23f9e8b7a79 372 Gene3D G3DSA:2.40.50.100 65 211 2.2E-67 T 14-10-2018 TSH58p_22895 ea8cdca6618de3facd0bac9044918a3b 473 SUPERFAMILY SSF51905 11 469 7.16E-45 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_22895 ea8cdca6618de3facd0bac9044918a3b 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 17 39 7.1E-6 T 14-10-2018 TSH58p_22895 ea8cdca6618de3facd0bac9044918a3b 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 51 66 7.1E-6 T 14-10-2018 TSH58p_22895 ea8cdca6618de3facd0bac9044918a3b 473 Pfam PF00890 FAD binding domain 18 441 3.0E-57 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_22895 ea8cdca6618de3facd0bac9044918a3b 473 Gene3D G3DSA:3.50.50.60 18 463 2.3E-112 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_22895 ea8cdca6618de3facd0bac9044918a3b 473 SUPERFAMILY SSF56425 258 402 7.63E-27 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_22895 ea8cdca6618de3facd0bac9044918a3b 473 Gene3D G3DSA:3.90.700.10 251 398 2.3E-112 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_04410 6dbbf3b45f7349bd386af3c518e3e73f 425 Pfam PF13481 AAA domain 57 230 6.2E-31 T 14-10-2018 TSH58p_04410 6dbbf3b45f7349bd386af3c518e3e73f 425 SUPERFAMILY SSF52540 72 253 1.5E-5 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_04410 6dbbf3b45f7349bd386af3c518e3e73f 425 Gene3D G3DSA:3.40.50.300 54 293 3.2E-29 T 14-10-2018 TSH58p_01950 2759eda9d62fa309cdb041b61e75fed9 464 Gene3D G3DSA:3.40.50.720 24 229 7.1E-63 T 14-10-2018 TSH58p_01950 2759eda9d62fa309cdb041b61e75fed9 464 PIRSF PIRSF000124 37 460 2.8E-64 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 TSH58p_01950 2759eda9d62fa309cdb041b61e75fed9 464 SUPERFAMILY SSF52413 342 453 1.31E-25 T 14-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 TSH58p_01950 2759eda9d62fa309cdb041b61e75fed9 464 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 235 325 2.0E-28 T 14-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSH58p_01950 2759eda9d62fa309cdb041b61e75fed9 464 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 39 449 2.2E-128 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 TSH58p_01950 2759eda9d62fa309cdb041b61e75fed9 464 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 353 451 2.8E-20 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSH58p_01950 2759eda9d62fa309cdb041b61e75fed9 464 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 38 213 1.5E-42 T 14-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSH58p_01950 2759eda9d62fa309cdb041b61e75fed9 464 SUPERFAMILY SSF51735 39 228 5.18E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_01950 2759eda9d62fa309cdb041b61e75fed9 464 SMART SM00984 353 453 7.3E-30 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSH58p_01950 2759eda9d62fa309cdb041b61e75fed9 464 PIRSF PIRSF500136 27 463 1.1E-145 T 14-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 TSH58p_01950 2759eda9d62fa309cdb041b61e75fed9 464 Gene3D G3DSA:3.40.50.720 234 462 7.0E-65 T 14-10-2018 TSH58p_01950 2759eda9d62fa309cdb041b61e75fed9 464 SUPERFAMILY SSF48179 234 331 9.52E-30 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_24475 a504a8ebf230daaead56aae2a558c65a 137 SMART SM00422 1 70 1.7E-17 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_24475 a504a8ebf230daaead56aae2a558c65a 137 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 8.9E-7 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_24475 a504a8ebf230daaead56aae2a558c65a 137 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 8.9E-7 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_24475 a504a8ebf230daaead56aae2a558c65a 137 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 8.9E-7 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_24475 a504a8ebf230daaead56aae2a558c65a 137 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_24475 a504a8ebf230daaead56aae2a558c65a 137 Pfam PF09278 MerR, DNA binding 45 101 1.8E-6 T 14-10-2018 IPR015358 Transcription regulator MerR, DNA binding TSH58p_24475 a504a8ebf230daaead56aae2a558c65a 137 Gene3D G3DSA:1.10.1660.10 1 130 6.8E-30 T 14-10-2018 TSH58p_24475 a504a8ebf230daaead56aae2a558c65a 137 SUPERFAMILY SSF46955 1 111 3.59E-28 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily TSH58p_24475 a504a8ebf230daaead56aae2a558c65a 137 Pfam PF00376 MerR family regulatory protein 2 39 2.0E-14 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_00355 3439eee4603502ef8698fe7b4e5be5dc 573 SUPERFAMILY SSF90123 11 311 2.75E-35 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_00355 3439eee4603502ef8698fe7b4e5be5dc 573 Pfam PF00664 ABC transporter transmembrane region 21 285 3.8E-8 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TSH58p_00355 3439eee4603502ef8698fe7b4e5be5dc 573 Gene3D G3DSA:3.40.50.300 318 562 5.7E-69 T 14-10-2018 TSH58p_00355 3439eee4603502ef8698fe7b4e5be5dc 573 Gene3D G3DSA:1.20.1560.10 8 313 1.0E-24 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_00355 3439eee4603502ef8698fe7b4e5be5dc 573 ProSitePatterns PS00211 ABC transporters family signature. 466 480 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_00355 3439eee4603502ef8698fe7b4e5be5dc 573 TIGRFAM TIGR01842 type_I_sec_PrtD: type I secretion system ATPase 18 554 1.1E-187 T 14-10-2018 IPR010128 ATPase, type I secretion system, PrtD GO:0005524|GO:0008565|GO:0016021|GO:0030253|GO:0030256 TSH58p_00355 3439eee4603502ef8698fe7b4e5be5dc 573 SMART SM00382 355 555 2.3E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_00355 3439eee4603502ef8698fe7b4e5be5dc 573 Pfam PF00005 ABC transporter 346 493 2.3E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_00355 3439eee4603502ef8698fe7b4e5be5dc 573 SUPERFAMILY SSF52540 319 553 3.75E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_25040 40180cf5324375e3d4ddab19e6512125 286 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 113 282 9.9E-63 T 14-10-2018 IPR005273 Uracil-DNA glycosylase family 4 TSH58p_25040 40180cf5324375e3d4ddab19e6512125 286 SMART SM00986 126 278 7.2E-41 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSH58p_25040 40180cf5324375e3d4ddab19e6512125 286 Pfam PF03167 Uracil DNA glycosylase superfamily 128 277 3.8E-45 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSH58p_25040 40180cf5324375e3d4ddab19e6512125 286 SUPERFAMILY SSF52141 99 284 5.23E-62 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSH58p_25040 40180cf5324375e3d4ddab19e6512125 286 Gene3D G3DSA:3.40.470.10 87 284 4.1E-68 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSH58p_25040 40180cf5324375e3d4ddab19e6512125 286 SMART SM00987 126 278 7.2E-41 T 14-10-2018 TSH58p_10330 ead4654bf874882102b7852bbe622455 1174 SUPERFAMILY SSF51735 364 792 4.72E-5 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_10330 ead4654bf874882102b7852bbe622455 1174 Gene3D G3DSA:3.50.50.60 520 637 4.6E-5 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_10330 ead4654bf874882102b7852bbe622455 1174 SUPERFAMILY SSF51971 377 689 5.89E-17 T 14-10-2018 TSH58p_10330 ead4654bf874882102b7852bbe622455 1174 SUPERFAMILY SSF63380 849 947 9.02E-11 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TSH58p_10330 ead4654bf874882102b7852bbe622455 1174 SUPERFAMILY SSF52343 944 1132 8.93E-13 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TSH58p_10330 ead4654bf874882102b7852bbe622455 1174 Gene3D G3DSA:3.40.50.80 949 1081 5.4E-9 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TSH58p_10330 ead4654bf874882102b7852bbe622455 1174 Gene3D G3DSA:2.40.30.10 847 947 5.9E-10 T 14-10-2018 TSH58p_26400 e98a419ae4f91d6cce3f282a72cd88d3 1021 SUPERFAMILY SSF50692 832 1018 1.18E-40 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TSH58p_26400 e98a419ae4f91d6cce3f282a72cd88d3 1021 SUPERFAMILY SSF53706 36 853 7.33E-293 T 14-10-2018 TSH58p_26400 e98a419ae4f91d6cce3f282a72cd88d3 1021 Gene3D G3DSA:3.30.200.210 33 151 1.6E-19 T 14-10-2018 TSH58p_26400 e98a419ae4f91d6cce3f282a72cd88d3 1021 Gene3D G3DSA:3.40.50.740 526 685 1.7E-56 T 14-10-2018 TSH58p_26400 e98a419ae4f91d6cce3f282a72cd88d3 1021 Gene3D G3DSA:3.40.228.10 192 484 5.5E-83 T 14-10-2018 TSH58p_26400 e98a419ae4f91d6cce3f282a72cd88d3 1021 Gene3D G3DSA:3.40.228.10 728 842 3.9E-27 T 14-10-2018 TSH58p_26400 e98a419ae4f91d6cce3f282a72cd88d3 1021 Pfam PF01568 Molydopterin dinucleotide binding domain 896 1011 4.2E-14 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TSH58p_26400 e98a419ae4f91d6cce3f282a72cd88d3 1021 SMART SM00926 43 104 1.6E-23 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_26400 e98a419ae4f91d6cce3f282a72cd88d3 1021 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 48 66 - T 14-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 TSH58p_26400 e98a419ae4f91d6cce3f282a72cd88d3 1021 Pfam PF00384 Molybdopterin oxidoreductase 107 593 6.5E-32 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_26400 e98a419ae4f91d6cce3f282a72cd88d3 1021 Gene3D G3DSA:2.40.40.20 843 1018 6.8E-74 T 14-10-2018 TSH58p_26400 e98a419ae4f91d6cce3f282a72cd88d3 1021 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 44 103 1.3E-18 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_26400 e98a419ae4f91d6cce3f282a72cd88d3 1021 TIGRFAM TIGR01553 formate-DH-alph: formate dehydrogenase-N alpha subunit 2 1017 0.0 T 14-10-2018 IPR006443 Formate dehydrogenase-N, alpha subunit GO:0008863|GO:0009055|GO:0043546|GO:0045333|GO:0047111 TSH58p_16850 081815fb9b9479b2e8a6503a5a3af6c6 587 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 458 567 2.7E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_16850 081815fb9b9479b2e8a6503a5a3af6c6 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 495 509 4.9E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_16850 081815fb9b9479b2e8a6503a5a3af6c6 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 530 548 4.9E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_16850 081815fb9b9479b2e8a6503a5a3af6c6 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 554 567 4.9E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_16850 081815fb9b9479b2e8a6503a5a3af6c6 587 SUPERFAMILY SSF47384 329 412 5.1E-23 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_16850 081815fb9b9479b2e8a6503a5a3af6c6 587 Pfam PF00512 His Kinase A (phospho-acceptor) domain 343 411 1.5E-20 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_16850 081815fb9b9479b2e8a6503a5a3af6c6 587 SMART SM00388 343 411 3.3E-25 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_16850 081815fb9b9479b2e8a6503a5a3af6c6 587 Gene3D G3DSA:3.30.565.10 407 568 2.7E-42 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_16850 081815fb9b9479b2e8a6503a5a3af6c6 587 Gene3D G3DSA:1.10.287.130 307 406 2.0E-29 T 14-10-2018 TSH58p_16850 081815fb9b9479b2e8a6503a5a3af6c6 587 SUPERFAMILY SSF55874 400 569 1.3E-45 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_16850 081815fb9b9479b2e8a6503a5a3af6c6 587 SMART SM00387 457 570 2.0E-36 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_22475 91930865b6f3809d4a35ccf9f70378cb 436 Pfam PF00005 ABC transporter 98 241 2.4E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_22475 91930865b6f3809d4a35ccf9f70378cb 436 SUPERFAMILY SSF50331 307 432 9.86E-10 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSH58p_22475 91930865b6f3809d4a35ccf9f70378cb 436 Gene3D G3DSA:2.40.50.140 355 422 1.5E-5 T 14-10-2018 TSH58p_22475 91930865b6f3809d4a35ccf9f70378cb 436 ProSitePatterns PS00211 ABC transporters family signature. 214 228 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_22475 91930865b6f3809d4a35ccf9f70378cb 436 SUPERFAMILY SSF52540 82 321 5.45E-79 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_22475 91930865b6f3809d4a35ccf9f70378cb 436 Gene3D G3DSA:3.40.50.300 81 301 2.8E-63 T 14-10-2018 TSH58p_22475 91930865b6f3809d4a35ccf9f70378cb 436 Gene3D G3DSA:2.40.50.940 302 430 1.5E-5 T 14-10-2018 TSH58p_22475 91930865b6f3809d4a35ccf9f70378cb 436 SMART SM00382 106 299 5.8E-19 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_22475 91930865b6f3809d4a35ccf9f70378cb 436 Pfam PF08402 TOBE domain 348 430 1.5E-5 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TSH58p_13330 c35c89fd8cc8103eb012efc25fa8a65e 562 Gene3D G3DSA:3.90.76.10 65 181 1.0E-37 T 14-10-2018 TSH58p_13330 c35c89fd8cc8103eb012efc25fa8a65e 562 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 103 455 1.1E-65 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain TSH58p_13330 c35c89fd8cc8103eb012efc25fa8a65e 562 PIRSF PIRSF002741 3 560 1.9E-70 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TSH58p_13330 c35c89fd8cc8103eb012efc25fa8a65e 562 SUPERFAMILY SSF53850 31 558 1.03E-96 T 14-10-2018 TSH58p_13330 c35c89fd8cc8103eb012efc25fa8a65e 562 Gene3D G3DSA:3.10.105.10 302 528 1.3E-62 T 14-10-2018 TSH58p_13330 c35c89fd8cc8103eb012efc25fa8a65e 562 Gene3D G3DSA:3.40.190.10 215 301 8.2E-15 T 14-10-2018 TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 Pfam PF08447 PAS fold 522 591 2.5E-13 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 Gene3D G3DSA:3.30.450.20 52 176 1.4E-18 T 14-10-2018 TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 Gene3D G3DSA:3.30.450.20 345 489 4.7E-37 T 14-10-2018 TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 SMART SM00065 190 345 2.0E-13 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 SUPERFAMILY SSF55785 66 163 1.74E-7 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 SMART SM00091 498 564 1.7E-8 T 14-10-2018 IPR000014 PAS domain TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 SMART SM00091 356 421 0.2 T 14-10-2018 IPR000014 PAS domain TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 Pfam PF01590 GAF domain 205 333 3.1E-11 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 Pfam PF00072 Response regulator receiver domain 879 984 2.2E-17 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 Pfam PF08448 PAS fold 362 477 1.7E-12 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 Pfam PF08448 PAS fold 64 171 4.1E-8 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 735 849 1.6E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 SMART SM00388 628 693 1.2E-4 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 PRINTS PR00344 Bacterial sensor protein C-terminal signature 782 796 5.2E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 PRINTS PR00344 Bacterial sensor protein C-terminal signature 800 810 5.2E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 PRINTS PR00344 Bacterial sensor protein C-terminal signature 837 850 5.2E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 PRINTS PR00344 Bacterial sensor protein C-terminal signature 813 831 5.2E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 Gene3D G3DSA:3.30.450.40 177 344 1.2E-17 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 SMART SM00086 430 475 120.0 T 14-10-2018 IPR001610 PAC motif TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 SMART SM00086 132 171 130.0 T 14-10-2018 IPR001610 PAC motif TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 SMART SM00086 570 606 0.0015 T 14-10-2018 IPR001610 PAC motif TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 SUPERFAMILY SSF55781 200 339 1.44E-20 T 14-10-2018 TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 SUPERFAMILY SSF52172 877 988 2.56E-28 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 SUPERFAMILY SSF55785 344 473 5.33E-10 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 SUPERFAMILY SSF55785 505 609 3.93E-23 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 SUPERFAMILY SSF55874 683 850 8.25E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 SUPERFAMILY SSF47384 619 691 6.08E-8 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 Gene3D G3DSA:3.30.565.10 696 854 5.0E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 496 613 3.5E-17 T 14-10-2018 IPR000014 PAS domain TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 Gene3D G3DSA:3.30.450.20 501 624 1.3E-22 T 14-10-2018 TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 SMART SM00387 734 853 2.1E-26 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 Gene3D G3DSA:3.40.50.2300 874 992 8.6E-29 T 14-10-2018 TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 SMART SM00448 877 984 4.2E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_20810 89ac5c78c00a2f761c1f9b79aeafb74b 994 Gene3D G3DSA:1.10.287.130 625 691 7.8E-17 T 14-10-2018 TSH58p_22960 8fdcf3723b4ba7b841d35ed66277e2a6 410 SUPERFAMILY SSF141130 16 383 4.97E-80 T 14-10-2018 TSH58p_22960 8fdcf3723b4ba7b841d35ed66277e2a6 410 Pfam PF03069 Acetamidase/Formamidase family 8 384 1.4E-177 T 14-10-2018 IPR004304 Acetamidase/Formamidase GO:0016811 TSH58p_22960 8fdcf3723b4ba7b841d35ed66277e2a6 410 Gene3D G3DSA:2.60.120.580 3 123 2.3E-16 T 14-10-2018 TSH58p_22960 8fdcf3723b4ba7b841d35ed66277e2a6 410 Gene3D G3DSA:2.60.120.580 199 281 2.9E-21 T 14-10-2018 TSH58p_22990 353112912fea0d725fdbe903562f5f8d 424 Pfam PF13433 Periplasmic binding protein domain 62 421 4.0E-135 T 14-10-2018 TSH58p_22990 353112912fea0d725fdbe903562f5f8d 424 Gene3D G3DSA:3.40.50.2300 64 391 1.2E-133 T 14-10-2018 TSH58p_22990 353112912fea0d725fdbe903562f5f8d 424 Gene3D G3DSA:3.40.50.2300 177 410 1.2E-133 T 14-10-2018 TSH58p_22990 353112912fea0d725fdbe903562f5f8d 424 SUPERFAMILY SSF53822 61 419 2.62E-93 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_22990 353112912fea0d725fdbe903562f5f8d 424 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 84 100 3.4E-6 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_22990 353112912fea0d725fdbe903562f5f8d 424 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 125 135 3.4E-6 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_22990 353112912fea0d725fdbe903562f5f8d 424 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 314 327 3.4E-6 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_22990 353112912fea0d725fdbe903562f5f8d 424 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 62 78 3.4E-6 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_22990 353112912fea0d725fdbe903562f5f8d 424 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 62 419 1.0E-166 T 14-10-2018 IPR017777 Urea ABC transporter, substrate-binding protein UrtA-like TSH58p_07595 70011d89bc25713f1107c14d01b2cdcc 391 PIRSF PIRSF000390 10 383 1.6E-90 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase TSH58p_07595 70011d89bc25713f1107c14d01b2cdcc 391 Gene3D G3DSA:3.40.640.10 3 253 9.1E-75 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_07595 70011d89bc25713f1107c14d01b2cdcc 391 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 21 376 1.7E-90 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase TSH58p_07595 70011d89bc25713f1107c14d01b2cdcc 391 SUPERFAMILY SSF53383 14 379 4.49E-86 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_07595 70011d89bc25713f1107c14d01b2cdcc 391 Gene3D G3DSA:3.90.1150.10 254 382 5.9E-22 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_08110 fce41c28eb600a9afcbf0959aca4e2df 162 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 32 155 4.7E-34 T 14-10-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 TSH58p_08110 fce41c28eb600a9afcbf0959aca4e2df 162 Pfam PF01814 Hemerythrin HHE cation binding domain 42 151 1.5E-13 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 TSH58p_08110 fce41c28eb600a9afcbf0959aca4e2df 162 SUPERFAMILY SSF47188 27 155 4.84E-35 T 14-10-2018 IPR035938 Hemerythrin-like superfamily TSH58p_08110 fce41c28eb600a9afcbf0959aca4e2df 162 Gene3D G3DSA:1.20.120.50 27 161 2.4E-39 T 14-10-2018 IPR035938 Hemerythrin-like superfamily TSH58p_08110 fce41c28eb600a9afcbf0959aca4e2df 162 ProSitePatterns PS00550 Hemerythrin family signature. 85 108 - T 14-10-2018 IPR016131 Haemerythrin, iron-binding site GO:0046872 TSH58p_09810 db7ce3473532022199477d6c54bb920d 316 Gene3D G3DSA:3.40.30.10 23 129 1.9E-26 T 14-10-2018 TSH58p_09810 db7ce3473532022199477d6c54bb920d 316 Pfam PF14559 Tetratricopeptide repeat 152 219 2.7E-11 T 14-10-2018 TSH58p_09810 db7ce3473532022199477d6c54bb920d 316 Pfam PF00085 Thioredoxin 28 126 2.9E-23 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 TSH58p_09810 db7ce3473532022199477d6c54bb920d 316 SUPERFAMILY SSF48452 142 289 1.14E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_09810 db7ce3473532022199477d6c54bb920d 316 Gene3D G3DSA:1.25.40.10 228 315 2.6E-28 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_09810 db7ce3473532022199477d6c54bb920d 316 Gene3D G3DSA:1.25.40.10 142 227 9.7E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_09810 db7ce3473532022199477d6c54bb920d 316 SUPERFAMILY SSF52833 27 131 1.47E-29 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_09810 db7ce3473532022199477d6c54bb920d 316 Pfam PF14561 Tetratricopeptide repeat 226 315 1.1E-32 T 14-10-2018 TSH58p_09810 db7ce3473532022199477d6c54bb920d 316 ProSitePatterns PS00194 Thioredoxin family active site. 45 63 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 4126 4235 1.0E-24 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 SUPERFAMILY SSF141072 5009 5128 1.57E-22 T 14-10-2018 IPR038081 CalX-like domain superfamily TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 6171 6189 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 SUPERFAMILY SSF69318 5 270 6.41E-38 T 14-10-2018 TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 SUPERFAMILY SSF51120 704 904 1.78E-11 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.2030 5006 5141 1.3E-19 T 14-10-2018 IPR038081 CalX-like domain superfamily TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.2030 4448 4587 3.5E-18 T 14-10-2018 IPR038081 CalX-like domain superfamily TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 SUPERFAMILY SSF51120 5980 6115 2.22E-23 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.150.10.10 6156 6274 1.1E-21 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 SUPERFAMILY SSF51120 525 697 6.28E-7 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 SMART SM00736 4135 4235 4.2E-45 T 14-10-2018 IPR006644 Dystroglycan-type cadherin-like GO:0016020 TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 SUPERFAMILY SSF51120 6070 6258 2.01E-29 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 SMART SM00237 4446 4553 8.3E-4 T 14-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 SMART SM00237 4998 5104 0.0021 T 14-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF03160 Calx-beta domain 4477 4552 1.9E-4 T 14-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF03160 Calx-beta domain 5024 5104 0.0018 T 14-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 85 152 1.1E-10 T 14-10-2018 TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 3158 3187 0.033 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 2168 2197 0.033 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 3257 3286 0.033 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 1376 1405 0.033 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 3059 3088 0.033 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 1277 1304 0.023 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 5657 5691 2.8 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 3356 3385 0.033 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 2467 2492 0.087 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 1871 1900 0.033 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 2662 2690 0.01 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 3653 3682 0.033 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 3454 3484 0.015 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 3554 3583 0.033 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 2762 2789 0.023 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 2564 2591 0.023 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 3752 3781 0.033 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 1477 1502 0.087 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 1772 1801 0.033 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 2861 2890 0.033 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 1970 1999 0.033 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 2962 2987 0.087 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 2366 2395 0.033 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 1574 1601 0.023 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 2069 2098 0.033 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 1673 1702 0.033 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 3851 3880 0.033 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 1180 1207 0.075 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Pfam PF12245 Bacterial Ig-like domain (group 3) 2267 2294 0.023 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.150.10.10 6043 6102 9.3E-12 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.150.10.10 6103 6155 4.3E-11 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.150.10.10 5976 6042 3.4E-6 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 SUPERFAMILY SSF49313 4133 4233 1.67E-26 T 14-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 1712 1811 1.7E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 3098 3196 4.3E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 1218 1316 2.3E-18 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 1614 1711 2.1E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 3593 3692 1.8E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 1119 1216 4.9E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 1415 1513 6.0E-18 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 1019 1118 6.8E-13 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 2109 2206 9.0E-20 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 2307 2404 2.4E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 1812 1909 2.3E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 3296 3394 8.9E-20 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 3197 3295 2.4E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 2702 2801 4.0E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 2505 2602 9.1E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 2900 2998 2.9E-18 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 2604 2701 5.4E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 2009 2108 2.3E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 3494 3592 1.5E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 2208 2306 1.5E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 2999 3097 1.7E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 3693 3791 2.1E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 2405 2504 5.3E-18 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 1317 1414 2.4E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 1514 1613 3.8E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 3396 3493 2.7E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 2802 2899 4.7E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 1910 2008 4.5E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 3792 3890 5.9E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 Gene3D G3DSA:2.60.40.10 5593 5696 2.0E-11 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 SUPERFAMILY SSF141072 4455 4584 2.62E-24 T 14-10-2018 IPR038081 CalX-like domain superfamily TSH58p_01265 be4aa660a7f1425a0a80409ff3f87bb9 6277 SUPERFAMILY SSF51120 367 567 1.46E-9 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_12970 67047ee78790cc67f057936181a59786 339 SUPERFAMILY SSF53448 23 232 6.56E-35 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_12970 67047ee78790cc67f057936181a59786 339 Pfam PF00535 Glycosyl transferase family 2 26 157 1.2E-20 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_12970 67047ee78790cc67f057936181a59786 339 Gene3D G3DSA:3.90.550.10 17 240 3.5E-29 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_16120 3c6f87cdfc7214475189878984e75f6e 327 Hamap MF_00301 Homoserine kinase [thrB]. 1 326 167.258 T 14-10-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 TSH58p_16120 3c6f87cdfc7214475189878984e75f6e 327 SUPERFAMILY SSF56112 5 309 5.47E-88 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily TSH58p_16120 3c6f87cdfc7214475189878984e75f6e 327 TIGRFAM TIGR00938 thrB_alt: homoserine kinase 1 307 8.7E-122 T 14-10-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 TSH58p_16120 3c6f87cdfc7214475189878984e75f6e 327 Gene3D G3DSA:3.90.1200.10 106 319 3.1E-84 T 14-10-2018 TSH58p_16120 3c6f87cdfc7214475189878984e75f6e 327 Pfam PF01636 Phosphotransferase enzyme family 28 256 1.3E-38 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase TSH58p_16120 3c6f87cdfc7214475189878984e75f6e 327 Gene3D G3DSA:3.30.200.20 1 104 1.9E-38 T 14-10-2018 TSH58p_09435 140f41c442724aeb660abc376f913778 291 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 237 250 - T 14-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site TSH58p_09435 140f41c442724aeb660abc376f913778 291 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 14-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site TSH58p_09435 140f41c442724aeb660abc376f913778 291 Gene3D G3DSA:3.40.50.720 2 123 1.3E-53 T 14-10-2018 TSH58p_09435 140f41c442724aeb660abc376f913778 291 SMART SM00881 4 100 8.8E-38 T 14-10-2018 IPR003781 CoA-binding GO:0048037 TSH58p_09435 140f41c442724aeb660abc376f913778 291 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 288 9.8E-139 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSH58p_09435 140f41c442724aeb660abc376f913778 291 Pfam PF00549 CoA-ligase 151 263 5.8E-18 T 14-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSH58p_09435 140f41c442724aeb660abc376f913778 291 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 289 42.587 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSH58p_09435 140f41c442724aeb660abc376f913778 291 Gene3D G3DSA:3.40.50.261 124 290 1.2E-70 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSH58p_09435 140f41c442724aeb660abc376f913778 291 PIRSF PIRSF001553 1 291 8.0E-132 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSH58p_09435 140f41c442724aeb660abc376f913778 291 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 3.4E-37 T 14-10-2018 TSH58p_09435 140f41c442724aeb660abc376f913778 291 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 3.4E-37 T 14-10-2018 TSH58p_09435 140f41c442724aeb660abc376f913778 291 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 3.4E-37 T 14-10-2018 TSH58p_09435 140f41c442724aeb660abc376f913778 291 PRINTS PR01798 Succinyl-CoA synthase signature 241 258 3.4E-37 T 14-10-2018 TSH58p_09435 140f41c442724aeb660abc376f913778 291 Pfam PF02629 CoA binding domain 6 99 1.8E-32 T 14-10-2018 IPR003781 CoA-binding GO:0048037 TSH58p_09435 140f41c442724aeb660abc376f913778 291 SUPERFAMILY SSF52210 123 288 9.29E-52 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSH58p_09435 140f41c442724aeb660abc376f913778 291 SUPERFAMILY SSF51735 1 122 3.68E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_20780 8c6f1a052a4959b3e155c60fd02d9a46 528 Pfam PF01019 Gamma-glutamyltranspeptidase 33 523 4.9E-136 T 14-10-2018 TSH58p_20780 8c6f1a052a4959b3e155c60fd02d9a46 528 Gene3D G3DSA:1.10.246.130 245 350 1.4E-18 T 14-10-2018 TSH58p_20780 8c6f1a052a4959b3e155c60fd02d9a46 528 SUPERFAMILY SSF56235 4 528 1.93E-158 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_20780 8c6f1a052a4959b3e155c60fd02d9a46 528 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 405 420 5.0E-35 T 14-10-2018 TSH58p_20780 8c6f1a052a4959b3e155c60fd02d9a46 528 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 129 148 5.0E-35 T 14-10-2018 TSH58p_20780 8c6f1a052a4959b3e155c60fd02d9a46 528 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 111 129 5.0E-35 T 14-10-2018 TSH58p_20780 8c6f1a052a4959b3e155c60fd02d9a46 528 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 374 392 5.0E-35 T 14-10-2018 TSH58p_20780 8c6f1a052a4959b3e155c60fd02d9a46 528 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 40 65 5.0E-35 T 14-10-2018 TSH58p_20780 8c6f1a052a4959b3e155c60fd02d9a46 528 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 258 277 5.0E-35 T 14-10-2018 TSH58p_20780 8c6f1a052a4959b3e155c60fd02d9a46 528 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 350 368 5.0E-35 T 14-10-2018 TSH58p_20780 8c6f1a052a4959b3e155c60fd02d9a46 528 Gene3D G3DSA:3.60.20.40 351 528 3.2E-56 T 14-10-2018 TSH58p_08095 f2d69ac6d3f184843cc330afc4548000 160 ProSitePatterns PS00550 Hemerythrin family signature. 65 88 - T 14-10-2018 IPR016131 Haemerythrin, iron-binding site GO:0046872 TSH58p_08095 f2d69ac6d3f184843cc330afc4548000 160 SUPERFAMILY SSF47188 10 135 4.97E-27 T 14-10-2018 IPR035938 Hemerythrin-like superfamily TSH58p_08095 f2d69ac6d3f184843cc330afc4548000 160 Pfam PF01814 Hemerythrin HHE cation binding domain 20 132 1.1E-5 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 TSH58p_08095 f2d69ac6d3f184843cc330afc4548000 160 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 13 135 1.1E-28 T 14-10-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 TSH58p_08095 f2d69ac6d3f184843cc330afc4548000 160 Gene3D G3DSA:1.20.120.50 7 140 4.3E-28 T 14-10-2018 IPR035938 Hemerythrin-like superfamily TSH58p_03400 c3afbadd25fefe7246a7a2715d5266e3 409 Gene3D G3DSA:1.10.287.130 138 241 9.8E-19 T 14-10-2018 TSH58p_03400 c3afbadd25fefe7246a7a2715d5266e3 409 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 292 399 1.4E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_03400 c3afbadd25fefe7246a7a2715d5266e3 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 347 357 3.3E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_03400 c3afbadd25fefe7246a7a2715d5266e3 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 398 3.3E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_03400 c3afbadd25fefe7246a7a2715d5266e3 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 329 343 3.3E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_03400 c3afbadd25fefe7246a7a2715d5266e3 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 378 3.3E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_03400 c3afbadd25fefe7246a7a2715d5266e3 409 SMART SM00448 7 120 5.6E-39 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_03400 c3afbadd25fefe7246a7a2715d5266e3 409 Gene3D G3DSA:3.30.565.10 246 403 1.4E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_03400 c3afbadd25fefe7246a7a2715d5266e3 409 Pfam PF00072 Response regulator receiver domain 9 120 1.1E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_03400 c3afbadd25fefe7246a7a2715d5266e3 409 SUPERFAMILY SSF52172 5 140 2.28E-39 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_03400 c3afbadd25fefe7246a7a2715d5266e3 409 SUPERFAMILY SSF55874 239 399 4.85E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_03400 c3afbadd25fefe7246a7a2715d5266e3 409 SMART SM00387 288 401 7.4E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_03400 c3afbadd25fefe7246a7a2715d5266e3 409 Gene3D G3DSA:3.40.50.2300 3 134 6.1E-37 T 14-10-2018 TSH58p_00040 c3afbadd25fefe7246a7a2715d5266e3 409 Gene3D G3DSA:1.10.287.130 138 241 9.8E-19 T 14-10-2018 TSH58p_00040 c3afbadd25fefe7246a7a2715d5266e3 409 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 292 399 1.4E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_00040 c3afbadd25fefe7246a7a2715d5266e3 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 347 357 3.3E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_00040 c3afbadd25fefe7246a7a2715d5266e3 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 398 3.3E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_00040 c3afbadd25fefe7246a7a2715d5266e3 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 329 343 3.3E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_00040 c3afbadd25fefe7246a7a2715d5266e3 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 378 3.3E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_00040 c3afbadd25fefe7246a7a2715d5266e3 409 SMART SM00448 7 120 5.6E-39 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_00040 c3afbadd25fefe7246a7a2715d5266e3 409 Gene3D G3DSA:3.30.565.10 246 403 1.4E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_00040 c3afbadd25fefe7246a7a2715d5266e3 409 Pfam PF00072 Response regulator receiver domain 9 120 1.1E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_00040 c3afbadd25fefe7246a7a2715d5266e3 409 SUPERFAMILY SSF52172 5 140 2.28E-39 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_00040 c3afbadd25fefe7246a7a2715d5266e3 409 SUPERFAMILY SSF55874 239 399 4.85E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_00040 c3afbadd25fefe7246a7a2715d5266e3 409 SMART SM00387 288 401 7.4E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_00040 c3afbadd25fefe7246a7a2715d5266e3 409 Gene3D G3DSA:3.40.50.2300 3 134 6.1E-37 T 14-10-2018 TSH58p_24090 cd3be1781a160f2483852298287c31dc 443 Gene3D G3DSA:3.40.50.300 7 194 1.5E-22 T 14-10-2018 TSH58p_24090 cd3be1781a160f2483852298287c31dc 443 SUPERFAMILY SSF52540 8 203 9.46E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_24090 cd3be1781a160f2483852298287c31dc 443 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 251 441 1.5E-34 T 14-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 TSH58p_24090 cd3be1781a160f2483852298287c31dc 443 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 11 410 2.7E-101 T 14-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 TSH58p_24090 cd3be1781a160f2483852298287c31dc 443 Hamap MF_00027 Hydrogenobyrinate a,c-diamide synthase [cobB]. 6 443 41.967 T 14-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 TSH58p_24090 cd3be1781a160f2483852298287c31dc 443 SUPERFAMILY SSF52317 250 442 7.95E-33 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_24090 cd3be1781a160f2483852298287c31dc 443 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 11 195 1.7E-15 T 14-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TSH58p_24090 cd3be1781a160f2483852298287c31dc 443 Gene3D G3DSA:3.40.50.880 259 440 2.3E-11 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_24380 9596dd1b631c8bf15bcbbcf26bc4c0a7 375 Pfam PF04055 Radical SAM superfamily 33 185 8.3E-15 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSH58p_24380 9596dd1b631c8bf15bcbbcf26bc4c0a7 375 SUPERFAMILY SSF102114 23 307 4.45E-53 T 14-10-2018 TSH58p_24380 9596dd1b631c8bf15bcbbcf26bc4c0a7 375 SMART SM00729 28 227 0.0077 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSH58p_24380 9596dd1b631c8bf15bcbbcf26bc4c0a7 375 TIGRFAM TIGR03470 HpnH: hopanoid biosynthesis associated radical SAM protein HpnH 1 318 1.3E-167 T 14-10-2018 IPR017833 Hopanoid biosynthesis associated radical SAM protein HpnH TSH58p_24380 9596dd1b631c8bf15bcbbcf26bc4c0a7 375 Pfam PF11946 Domain of unknown function (DUF3463) 195 327 2.4E-60 T 14-10-2018 IPR022563 Domain of unknown function DUF3463 TSH58p_24380 9596dd1b631c8bf15bcbbcf26bc4c0a7 375 Gene3D G3DSA:3.20.20.70 28 289 9.9E-32 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_25880 d6b0475c9f74e64988170e51d192e3e1 525 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 6 50 1.1E-18 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 TSH58p_25880 d6b0475c9f74e64988170e51d192e3e1 525 PIRSF PIRSF000774 1 521 5.6E-145 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 TSH58p_25880 d6b0475c9f74e64988170e51d192e3e1 525 Pfam PF04552 Sigma-54, DNA binding domain 360 519 4.7E-71 T 14-10-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding TSH58p_25880 d6b0475c9f74e64988170e51d192e3e1 525 Gene3D G3DSA:1.10.10.60 461 518 2.1E-21 T 14-10-2018 TSH58p_25880 d6b0475c9f74e64988170e51d192e3e1 525 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 11 518 5.8E-127 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 TSH58p_25880 d6b0475c9f74e64988170e51d192e3e1 525 PRINTS PR00045 Sigma-54 factor signature 231 248 4.4E-33 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 TSH58p_25880 d6b0475c9f74e64988170e51d192e3e1 525 PRINTS PR00045 Sigma-54 factor signature 494 512 4.4E-33 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 TSH58p_25880 d6b0475c9f74e64988170e51d192e3e1 525 PRINTS PR00045 Sigma-54 factor signature 435 446 4.4E-33 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 TSH58p_25880 d6b0475c9f74e64988170e51d192e3e1 525 PRINTS PR00045 Sigma-54 factor signature 419 431 4.4E-33 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 TSH58p_25880 d6b0475c9f74e64988170e51d192e3e1 525 Pfam PF04963 Sigma-54 factor, core binding domain 158 345 1.4E-47 T 14-10-2018 IPR007046 RNA polymerase sigma factor 54, core-binding domain GO:0003677|GO:0006352 TSH58p_25880 d6b0475c9f74e64988170e51d192e3e1 525 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 499 506 - T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 TSH58p_25880 d6b0475c9f74e64988170e51d192e3e1 525 Gene3D G3DSA:1.10.10.1330 164 285 1.0E-21 T 14-10-2018 IPR038709 RNA polymerase sigma-54 factor, core-binding domain superfamily TSH58p_25880 d6b0475c9f74e64988170e51d192e3e1 525 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 407 426 - T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 TSH58p_02735 dd4933fda64c92bed447127c2e8f048b 520 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 8 171 1.5E-39 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 TSH58p_02735 dd4933fda64c92bed447127c2e8f048b 520 Gene3D G3DSA:3.40.50.970 5 179 7.6E-46 T 14-10-2018 TSH58p_02735 dd4933fda64c92bed447127c2e8f048b 520 Gene3D G3DSA:3.40.50.970 332 520 3.8E-41 T 14-10-2018 TSH58p_02735 dd4933fda64c92bed447127c2e8f048b 520 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 379 517 1.7E-23 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TSH58p_02735 dd4933fda64c92bed447127c2e8f048b 520 SUPERFAMILY SSF52518 344 520 3.57E-37 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_02735 dd4933fda64c92bed447127c2e8f048b 520 SUPERFAMILY SSF52518 2 185 4.02E-44 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_28590 6e7a592d24e846a03acbf86376873db3 438 Gene3D G3DSA:3.40.190.10 74 156 1.8E-6 T 14-10-2018 TSH58p_28590 6e7a592d24e846a03acbf86376873db3 438 SUPERFAMILY SSF53850 54 436 9.24E-52 T 14-10-2018 TSH58p_28590 6e7a592d24e846a03acbf86376873db3 438 Gene3D G3DSA:3.40.190.10 186 353 1.5E-27 T 14-10-2018 TSH58p_28590 6e7a592d24e846a03acbf86376873db3 438 Pfam PF13416 Bacterial extracellular solute-binding protein 69 375 8.7E-21 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSH58p_28590 6e7a592d24e846a03acbf86376873db3 438 Gene3D G3DSA:3.40.190.10 157 180 1.8E-6 T 14-10-2018 TSH58p_23815 e8f186f11ede7b0506fb22420c75bdce 541 SUPERFAMILY SSF48452 290 510 7.59E-20 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_23815 e8f186f11ede7b0506fb22420c75bdce 541 SMART SM00862 21 96 2.7E-17 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_23815 e8f186f11ede7b0506fb22420c75bdce 541 SUPERFAMILY SSF46894 3 97 1.02E-20 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_23815 e8f186f11ede7b0506fb22420c75bdce 541 Gene3D G3DSA:1.10.10.10 1 97 6.9E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_23815 e8f186f11ede7b0506fb22420c75bdce 541 Pfam PF00486 Transcriptional regulatory protein, C terminal 22 96 3.5E-17 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_23815 e8f186f11ede7b0506fb22420c75bdce 541 Gene3D G3DSA:1.25.40.10 242 528 1.3E-23 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_23030 3f087266c8372afbad23014e8fa56d2f 347 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 244 331 4.6E-26 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_23030 3f087266c8372afbad23014e8fa56d2f 347 SMART SM00382 52 244 6.6E-19 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_23030 3f087266c8372afbad23014e8fa56d2f 347 Pfam PF00005 ABC transporter 43 194 6.0E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_23030 3f087266c8372afbad23014e8fa56d2f 347 Gene3D G3DSA:3.40.50.300 21 339 4.0E-106 T 14-10-2018 TSH58p_23030 3f087266c8372afbad23014e8fa56d2f 347 SUPERFAMILY SSF52540 23 266 3.22E-75 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_23030 3f087266c8372afbad23014e8fa56d2f 347 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 246 311 5.6E-16 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_23030 3f087266c8372afbad23014e8fa56d2f 347 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_14010 c3020b92234a63fe537b580697baac30 850 Gene3D G3DSA:3.40.50.300 183 354 2.2E-51 T 14-10-2018 TSH58p_14010 c3020b92234a63fe537b580697baac30 850 SMART SM00490 234 337 7.9E-13 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_14010 c3020b92234a63fe537b580697baac30 850 Gene3D G3DSA:1.20.120.1080 382 477 5.4E-13 T 14-10-2018 TSH58p_14010 c3020b92234a63fe537b580697baac30 850 Pfam PF08482 ATP-dependent helicase C-terminal 705 836 9.9E-55 T 14-10-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal TSH58p_14010 c3020b92234a63fe537b580697baac30 850 Pfam PF04408 Helicase associated domain (HA2) 398 499 4.1E-14 T 14-10-2018 IPR007502 Helicase-associated domain GO:0004386 TSH58p_14010 c3020b92234a63fe537b580697baac30 850 PIRSF PIRSF005496 1 850 0.0 T 14-10-2018 TSH58p_14010 c3020b92234a63fe537b580697baac30 850 SMART SM00847 397 490 2.4E-18 T 14-10-2018 IPR007502 Helicase-associated domain GO:0004386 TSH58p_14010 c3020b92234a63fe537b580697baac30 850 SUPERFAMILY SSF52540 16 162 3.94E-26 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_14010 c3020b92234a63fe537b580697baac30 850 SMART SM00487 4 189 2.9E-19 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSH58p_14010 c3020b92234a63fe537b580697baac30 850 Gene3D G3DSA:3.40.50.300 3 182 8.0E-54 T 14-10-2018 TSH58p_14010 c3020b92234a63fe537b580697baac30 850 SUPERFAMILY SSF52540 158 440 9.73E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_14010 c3020b92234a63fe537b580697baac30 850 Pfam PF00271 Helicase conserved C-terminal domain 216 336 7.1E-12 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_14010 c3020b92234a63fe537b580697baac30 850 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 6 849 0.0 T 14-10-2018 IPR010225 ATP-dependent helicase HrpB GO:0008026 TSH58p_05700 22f85f446665ca02d9ad0a80bc33b1f8 131 Gene3D G3DSA:3.10.180.10 4 131 9.6E-47 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSH58p_05700 22f85f446665ca02d9ad0a80bc33b1f8 131 ProSitePatterns PS00934 Glyoxalase I signature 1. 8 29 - T 14-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 TSH58p_05700 22f85f446665ca02d9ad0a80bc33b1f8 131 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 3 131 5.0E-60 T 14-10-2018 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 TSH58p_05700 22f85f446665ca02d9ad0a80bc33b1f8 131 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 127 1.5E-21 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TSH58p_05700 22f85f446665ca02d9ad0a80bc33b1f8 131 SUPERFAMILY SSF54593 4 130 4.3E-35 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSH58p_05700 22f85f446665ca02d9ad0a80bc33b1f8 131 ProSitePatterns PS00935 Glyoxalase I signature 2. 73 85 - T 14-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 TSH58p_16885 ba329c380d27660692dab5e3a50ae133 151 Gene3D G3DSA:3.30.70.920 54 135 6.0E-25 T 14-10-2018 TSH58p_16885 ba329c380d27660692dab5e3a50ae133 151 SUPERFAMILY SSF46785 1 60 8.69E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_16885 ba329c380d27660692dab5e3a50ae133 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 3.5E-12 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSH58p_16885 ba329c380d27660692dab5e3a50ae133 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 3.5E-12 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSH58p_16885 ba329c380d27660692dab5e3a50ae133 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 3.5E-12 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSH58p_16885 ba329c380d27660692dab5e3a50ae133 151 Pfam PF01037 Lrp/AsnC ligand binding domain 72 138 2.7E-21 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TSH58p_16885 ba329c380d27660692dab5e3a50ae133 151 SUPERFAMILY SSF54909 61 148 7.24E-22 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel TSH58p_16885 ba329c380d27660692dab5e3a50ae133 151 SMART SM00344 1 108 2.3E-37 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TSH58p_16885 ba329c380d27660692dab5e3a50ae133 151 Gene3D G3DSA:1.10.10.10 2 53 1.6E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_16885 ba329c380d27660692dab5e3a50ae133 151 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 1.2E-16 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSH58p_19430 97202bd0c7a332506a4902610173b630 789 Gene3D G3DSA:3.30.365.10 378 760 9.3E-124 T 14-10-2018 TSH58p_19430 97202bd0c7a332506a4902610173b630 789 SUPERFAMILY SSF56003 133 783 1.83E-177 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 TSH58p_19430 97202bd0c7a332506a4902610173b630 789 SMART SM01008 29 140 3.4E-33 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead TSH58p_19430 97202bd0c7a332506a4902610173b630 789 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 30 140 6.7E-16 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead TSH58p_19430 97202bd0c7a332506a4902610173b630 789 Gene3D G3DSA:3.30.365.10 465 635 9.3E-124 T 14-10-2018 TSH58p_19430 97202bd0c7a332506a4902610173b630 789 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 156 720 7.8E-157 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 TSH58p_19430 97202bd0c7a332506a4902610173b630 789 SUPERFAMILY SSF54665 12 162 3.93E-34 T 14-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily TSH58p_19430 97202bd0c7a332506a4902610173b630 789 Gene3D G3DSA:3.90.1170.50 4 140 1.2E-33 T 14-10-2018 TSH58p_19430 97202bd0c7a332506a4902610173b630 789 Gene3D G3DSA:3.30.365.10 195 291 6.3E-61 T 14-10-2018 TSH58p_19430 97202bd0c7a332506a4902610173b630 789 Gene3D G3DSA:3.30.365.10 154 369 6.3E-61 T 14-10-2018 TSH58p_23455 106f59588afaa7b5ab36fe7cd4412392 291 PIRSF PIRSF001111 1 286 3.7E-115 T 14-10-2018 IPR016291 Isochorismatase GO:0008908 TSH58p_23455 106f59588afaa7b5ab36fe7cd4412392 291 PRINTS PR01398 Isochorismatase signature 112 134 2.7E-43 T 14-10-2018 IPR016291 Isochorismatase GO:0008908 TSH58p_23455 106f59588afaa7b5ab36fe7cd4412392 291 PRINTS PR01398 Isochorismatase signature 186 203 2.7E-43 T 14-10-2018 IPR016291 Isochorismatase GO:0008908 TSH58p_23455 106f59588afaa7b5ab36fe7cd4412392 291 PRINTS PR01398 Isochorismatase signature 2 14 2.7E-43 T 14-10-2018 IPR016291 Isochorismatase GO:0008908 TSH58p_23455 106f59588afaa7b5ab36fe7cd4412392 291 PRINTS PR01398 Isochorismatase signature 168 186 2.7E-43 T 14-10-2018 IPR016291 Isochorismatase GO:0008908 TSH58p_23455 106f59588afaa7b5ab36fe7cd4412392 291 PRINTS PR01398 Isochorismatase signature 80 99 2.7E-43 T 14-10-2018 IPR016291 Isochorismatase GO:0008908 TSH58p_23455 106f59588afaa7b5ab36fe7cd4412392 291 PRINTS PR01398 Isochorismatase signature 63 80 2.7E-43 T 14-10-2018 IPR016291 Isochorismatase GO:0008908 TSH58p_23455 106f59588afaa7b5ab36fe7cd4412392 291 Pfam PF00857 Isochorismatase family 32 201 2.9E-36 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 TSH58p_23455 106f59588afaa7b5ab36fe7cd4412392 291 Gene3D G3DSA:3.40.50.850 1 208 3.3E-71 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TSH58p_23455 106f59588afaa7b5ab36fe7cd4412392 291 SUPERFAMILY SSF52499 1 223 2.09E-62 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TSH58p_23455 106f59588afaa7b5ab36fe7cd4412392 291 Gene3D G3DSA:1.10.1200.10 213 283 4.5E-22 T 14-10-2018 IPR036736 ACP-like superfamily TSH58p_23455 106f59588afaa7b5ab36fe7cd4412392 291 SUPERFAMILY SSF47336 219 286 3.93E-8 T 14-10-2018 IPR036736 ACP-like superfamily TSH58p_23455 106f59588afaa7b5ab36fe7cd4412392 291 Pfam PF00550 Phosphopantetheine attachment site 227 275 3.6E-6 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain TSH58p_07790 9d61ceb1ff113793c49bc94ee662894a 723 Pfam PF01274 Malate synthase 18 695 3.0E-169 T 14-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TSH58p_07790 9d61ceb1ff113793c49bc94ee662894a 723 Gene3D G3DSA:3.20.20.360 7 578 5.5E-284 T 14-10-2018 TSH58p_07790 9d61ceb1ff113793c49bc94ee662894a 723 Gene3D G3DSA:2.170.170.11 135 264 5.5E-284 T 14-10-2018 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TSH58p_07790 9d61ceb1ff113793c49bc94ee662894a 723 Hamap MF_00641 Malate synthase G [glcB]. 1 723 415.901 T 14-10-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TSH58p_07790 9d61ceb1ff113793c49bc94ee662894a 723 Gene3D G3DSA:1.20.1220.12 581 723 5.6E-76 T 14-10-2018 TSH58p_07790 9d61ceb1ff113793c49bc94ee662894a 723 SUPERFAMILY SSF51645 2 720 0.0 T 14-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TSH58p_07790 9d61ceb1ff113793c49bc94ee662894a 723 TIGRFAM TIGR01345 malate_syn_G: malate synthase G 4 720 0.0 T 14-10-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TSH58p_18450 2ed6657e9bd85364614e152ea2123600 847 SUPERFAMILY SSF53448 557 820 6.83E-46 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_18450 2ed6657e9bd85364614e152ea2123600 847 Pfam PF00535 Glycosyl transferase family 2 301 410 2.8E-21 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_18450 2ed6657e9bd85364614e152ea2123600 847 Pfam PF00535 Glycosyl transferase family 2 565 747 7.0E-18 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_18450 2ed6657e9bd85364614e152ea2123600 847 SUPERFAMILY SSF53448 290 507 5.63E-42 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_18450 2ed6657e9bd85364614e152ea2123600 847 Gene3D G3DSA:3.90.550.10 242 545 8.0E-56 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_18450 2ed6657e9bd85364614e152ea2123600 847 Gene3D G3DSA:3.90.550.10 559 802 1.8E-42 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_03135 f9ed1b41d72411ace2707fd74eb8aabc 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 289 1.5E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_03135 f9ed1b41d72411ace2707fd74eb8aabc 301 Gene3D G3DSA:1.10.3720.10 59 296 1.8E-68 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_03135 f9ed1b41d72411ace2707fd74eb8aabc 301 SUPERFAMILY SSF161098 61 287 2.75E-62 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_18430 2447c53b809921b17422dde0d37c4a27 353 SUPERFAMILY SSF51735 2 341 8.0E-87 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_18430 2447c53b809921b17422dde0d37c4a27 353 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 3 342 1.6E-183 T 14-10-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 TSH58p_18430 2447c53b809921b17422dde0d37c4a27 353 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 336 1.8E-162 T 14-10-2018 IPR016040 NAD(P)-binding domain TSH58p_18430 2447c53b809921b17422dde0d37c4a27 353 Gene3D G3DSA:3.90.25.10 193 341 1.7E-168 T 14-10-2018 TSH58p_18430 2447c53b809921b17422dde0d37c4a27 353 Gene3D G3DSA:3.40.50.720 5 327 1.7E-168 T 14-10-2018 TSH58p_18430 2447c53b809921b17422dde0d37c4a27 353 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 3 346 57.093 T 14-10-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 TSH58p_27115 36ef96cf53ac6a3e983844913870f591 390 SMART SM00922 162 259 2.4E-19 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal TSH58p_27115 36ef96cf53ac6a3e983844913870f591 390 SUPERFAMILY SSF54826 1 139 1.51E-28 T 14-10-2018 TSH58p_27115 36ef96cf53ac6a3e983844913870f591 390 Gene3D G3DSA:3.20.20.120 129 389 2.6E-69 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TSH58p_27115 36ef96cf53ac6a3e983844913870f591 390 Pfam PF13378 Enolase C-terminal domain-like 165 374 2.4E-43 T 14-10-2018 IPR029065 Enolase C-terminal domain-like TSH58p_27115 36ef96cf53ac6a3e983844913870f591 390 Gene3D G3DSA:3.30.390.10 1 127 6.9E-65 T 14-10-2018 IPR029017 Enolase-like, N-terminal TSH58p_27115 36ef96cf53ac6a3e983844913870f591 390 SUPERFAMILY SSF51604 123 382 1.69E-55 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TSH58p_30170 6e3de26afdadc7bb0432b7619a0e6fc7 340 Pfam PF13020 Domain of unknown function (DUF3883) 200 270 3.3E-6 T 14-10-2018 IPR024975 Domain of unknown function DUF3883 TSH58p_30010 6e3de26afdadc7bb0432b7619a0e6fc7 340 Pfam PF13020 Domain of unknown function (DUF3883) 200 270 3.3E-6 T 14-10-2018 IPR024975 Domain of unknown function DUF3883 TSH58p_05165 b3e484b94870580463094223b3699787 585 Gene3D G3DSA:3.40.50.970 368 581 5.9E-57 T 14-10-2018 TSH58p_05165 b3e484b94870580463094223b3699787 585 SUPERFAMILY SSF52518 23 192 1.23E-42 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_05165 b3e484b94870580463094223b3699787 585 TIGRFAM TIGR03254 oxalate_oxc: oxalyl-CoA decarboxylase 21 575 4.5E-301 T 14-10-2018 IPR017660 Oxalyl-CoA decarboxylase GO:0008949|GO:0030976|GO:0033611|GO:0046872 KEGG: 00630+4.1.1.8|MetaCyc: PWY-6695|MetaCyc: PWY-6696|MetaCyc: PWY-7985 TSH58p_05165 b3e484b94870580463094223b3699787 585 Gene3D G3DSA:3.40.50.1220 207 366 5.8E-43 T 14-10-2018 TSH58p_05165 b3e484b94870580463094223b3699787 585 SUPERFAMILY SSF52518 386 564 1.27E-39 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_05165 b3e484b94870580463094223b3699787 585 SUPERFAMILY SSF52467 207 370 7.77E-40 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TSH58p_05165 b3e484b94870580463094223b3699787 585 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 412 556 4.9E-24 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TSH58p_05165 b3e484b94870580463094223b3699787 585 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 215 346 1.0E-32 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 TSH58p_05165 b3e484b94870580463094223b3699787 585 Gene3D G3DSA:3.40.50.970 14 206 7.8E-60 T 14-10-2018 TSH58p_05165 b3e484b94870580463094223b3699787 585 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 24 191 3.8E-45 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 TSH58p_08155 ef25909c3a2fc5d7b3f552cf13b62e7f 951 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 16 862 1.7E-259 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TSH58p_08155 ef25909c3a2fc5d7b3f552cf13b62e7f 951 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 3 946 20.25 T 14-10-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 TSH58p_08155 ef25909c3a2fc5d7b3f552cf13b62e7f 951 Gene3D G3DSA:1.10.730.20 656 947 1.0E-83 T 14-10-2018 TSH58p_08155 ef25909c3a2fc5d7b3f552cf13b62e7f 951 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 29 656 1.8E-192 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_08155 ef25909c3a2fc5d7b3f552cf13b62e7f 951 Pfam PF06827 Zinc finger found in FPG and IleRS 916 942 1.4E-6 T 14-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 TSH58p_08155 ef25909c3a2fc5d7b3f552cf13b62e7f 951 SUPERFAMILY SSF50677 207 419 2.22E-47 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TSH58p_08155 ef25909c3a2fc5d7b3f552cf13b62e7f 951 SUPERFAMILY SSF47323 668 946 5.01E-62 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_08155 ef25909c3a2fc5d7b3f552cf13b62e7f 951 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 59 70 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_08155 ef25909c3a2fc5d7b3f552cf13b62e7f 951 Gene3D G3DSA:3.40.50.620 26 645 7.3E-230 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_08155 ef25909c3a2fc5d7b3f552cf13b62e7f 951 Gene3D G3DSA:3.90.740.10 199 424 7.3E-230 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TSH58p_08155 ef25909c3a2fc5d7b3f552cf13b62e7f 951 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 543 556 3.1E-30 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TSH58p_08155 ef25909c3a2fc5d7b3f552cf13b62e7f 951 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 52 63 3.1E-30 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TSH58p_08155 ef25909c3a2fc5d7b3f552cf13b62e7f 951 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 234 257 3.1E-30 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TSH58p_08155 ef25909c3a2fc5d7b3f552cf13b62e7f 951 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 417 432 3.1E-30 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TSH58p_08155 ef25909c3a2fc5d7b3f552cf13b62e7f 951 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 577 586 3.1E-30 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TSH58p_08155 ef25909c3a2fc5d7b3f552cf13b62e7f 951 SUPERFAMILY SSF52374 5 662 4.83E-133 T 14-10-2018 TSH58p_08155 ef25909c3a2fc5d7b3f552cf13b62e7f 951 Pfam PF08264 Anticodon-binding domain of tRNA 700 857 4.9E-21 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TSH58p_25605 c9d0cc1526895da669e54f8ba7e48296 574 SUPERFAMILY SSF48452 385 535 1.87E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25605 c9d0cc1526895da669e54f8ba7e48296 574 Gene3D G3DSA:1.25.40.10 348 544 4.8E-15 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25605 c9d0cc1526895da669e54f8ba7e48296 574 SMART SM00028 403 436 480.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25605 c9d0cc1526895da669e54f8ba7e48296 574 SMART SM00028 437 470 110.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25605 c9d0cc1526895da669e54f8ba7e48296 574 SMART SM00028 501 534 0.018 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25130 fed749fb576b7099ac3cfecba974819f 291 PIRSF PIRSF015582 1 290 9.2E-73 T 14-10-2018 IPR011206 Citrate lyase beta subunit-like TSH58p_25130 fed749fb576b7099ac3cfecba974819f 291 SUPERFAMILY SSF51621 3 233 2.48E-53 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSH58p_25130 fed749fb576b7099ac3cfecba974819f 291 Gene3D G3DSA:3.20.20.60 1 290 4.9E-82 T 14-10-2018 TSH58p_25130 fed749fb576b7099ac3cfecba974819f 291 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 6 223 1.1E-37 T 14-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 TSH58p_01840 b2194e4f25867cb4c4cbda137cc2a18e 1035 Gene3D G3DSA:2.40.40.20 861 1024 4.9E-22 T 14-10-2018 TSH58p_01840 b2194e4f25867cb4c4cbda137cc2a18e 1035 Gene3D G3DSA:3.40.50.740 564 759 1.3E-19 T 14-10-2018 TSH58p_01840 b2194e4f25867cb4c4cbda137cc2a18e 1035 Pfam PF01568 Molydopterin dinucleotide binding domain 901 1006 8.8E-14 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TSH58p_01840 b2194e4f25867cb4c4cbda137cc2a18e 1035 SUPERFAMILY SSF53706 72 902 1.05E-110 T 14-10-2018 TSH58p_01840 b2194e4f25867cb4c4cbda137cc2a18e 1035 SUPERFAMILY SSF50692 884 1025 1.08E-25 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TSH58p_01840 b2194e4f25867cb4c4cbda137cc2a18e 1035 SMART SM00926 70 154 2.8E-11 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_01840 b2194e4f25867cb4c4cbda137cc2a18e 1035 Pfam PF00384 Molybdopterin oxidoreductase 269 694 2.1E-15 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_31440 ef29a9959c1b1c0aad986f699dc8cbdb 992 Gene3D G3DSA:3.50.50.60 616 979 4.4E-85 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_31440 ef29a9959c1b1c0aad986f699dc8cbdb 992 Pfam PF04324 BFD-like [2Fe-2S] binding domain 505 555 9.3E-10 T 14-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain TSH58p_31440 ef29a9959c1b1c0aad986f699dc8cbdb 992 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 13 92 6.9E-24 T 14-10-2018 TSH58p_31440 ef29a9959c1b1c0aad986f699dc8cbdb 992 Gene3D G3DSA:3.50.50.60 119 447 1.1E-39 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_31440 ef29a9959c1b1c0aad986f699dc8cbdb 992 Gene3D G3DSA:3.10.20.440 3 95 1.2E-18 T 14-10-2018 TSH58p_31440 ef29a9959c1b1c0aad986f699dc8cbdb 992 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 120 139 2.6E-18 T 14-10-2018 TSH58p_31440 ef29a9959c1b1c0aad986f699dc8cbdb 992 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 380 396 2.6E-18 T 14-10-2018 TSH58p_31440 ef29a9959c1b1c0aad986f699dc8cbdb 992 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 281 2.6E-18 T 14-10-2018 TSH58p_31440 ef29a9959c1b1c0aad986f699dc8cbdb 992 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 413 435 2.6E-18 T 14-10-2018 TSH58p_31440 ef29a9959c1b1c0aad986f699dc8cbdb 992 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 219 237 2.6E-18 T 14-10-2018 TSH58p_31440 ef29a9959c1b1c0aad986f699dc8cbdb 992 Pfam PF01266 FAD dependent oxidoreductase 616 973 8.8E-56 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TSH58p_31440 ef29a9959c1b1c0aad986f699dc8cbdb 992 SUPERFAMILY SSF51905 117 435 5.98E-29 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_31440 ef29a9959c1b1c0aad986f699dc8cbdb 992 Gene3D G3DSA:1.10.10.1100 496 564 4.0E-20 T 14-10-2018 TSH58p_31440 ef29a9959c1b1c0aad986f699dc8cbdb 992 Gene3D G3DSA:3.50.50.60 231 388 1.1E-39 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_31440 ef29a9959c1b1c0aad986f699dc8cbdb 992 Gene3D G3DSA:3.30.9.10 708 939 4.4E-85 T 14-10-2018 TSH58p_31440 ef29a9959c1b1c0aad986f699dc8cbdb 992 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 119 141 3.9E-9 T 14-10-2018 TSH58p_31440 ef29a9959c1b1c0aad986f699dc8cbdb 992 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 428 435 3.9E-9 T 14-10-2018 TSH58p_31440 ef29a9959c1b1c0aad986f699dc8cbdb 992 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 381 395 3.9E-9 T 14-10-2018 TSH58p_31440 ef29a9959c1b1c0aad986f699dc8cbdb 992 SUPERFAMILY SSF51905 615 991 6.91E-52 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_31440 ef29a9959c1b1c0aad986f699dc8cbdb 992 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 119 435 6.1E-21 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSH58p_31440 ef29a9959c1b1c0aad986f699dc8cbdb 992 SUPERFAMILY SSF54292 15 93 4.98E-18 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TSH58p_14800 59ec5e63286c9e73ee126ca1dde58853 203 Pfam PF13419 Haloacid dehalogenase-like hydrolase 62 184 3.6E-16 T 14-10-2018 TSH58p_14800 59ec5e63286c9e73ee126ca1dde58853 203 Gene3D G3DSA:3.40.50.1000 5 201 1.1E-38 T 14-10-2018 IPR023214 HAD superfamily TSH58p_14800 59ec5e63286c9e73ee126ca1dde58853 203 SUPERFAMILY SSF56784 6 198 3.37E-41 T 14-10-2018 IPR036412 HAD-like superfamily TSH58p_14800 59ec5e63286c9e73ee126ca1dde58853 203 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 95 181 3.7E-6 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_14800 59ec5e63286c9e73ee126ca1dde58853 203 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 79 183 8.5E-15 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_10595 ccfaa1977a1034273b1db0253696d03d 492 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 378 407 5.2E-20 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_10595 ccfaa1977a1034273b1db0253696d03d 492 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 349 376 5.2E-20 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_10595 ccfaa1977a1034273b1db0253696d03d 492 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 272 301 5.2E-20 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_10595 ccfaa1977a1034273b1db0253696d03d 492 Gene3D G3DSA:3.30.450.20 12 126 3.7E-34 T 14-10-2018 TSH58p_10595 ccfaa1977a1034273b1db0253696d03d 492 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 333 478 8.4E-30 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_10595 ccfaa1977a1034273b1db0253696d03d 492 Gene3D G3DSA:3.30.450.20 131 262 3.5E-21 T 14-10-2018 TSH58p_10595 ccfaa1977a1034273b1db0253696d03d 492 SUPERFAMILY SSF55785 142 245 4.89E-25 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_10595 ccfaa1977a1034273b1db0253696d03d 492 Gene3D G3DSA:1.10.287.950 263 478 1.3E-39 T 14-10-2018 TSH58p_10595 ccfaa1977a1034273b1db0253696d03d 492 SMART SM00086 206 248 1.6E-6 T 14-10-2018 IPR001610 PAC motif TSH58p_10595 ccfaa1977a1034273b1db0253696d03d 492 Pfam PF08447 PAS fold 157 241 1.6E-13 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 TSH58p_10595 ccfaa1977a1034273b1db0253696d03d 492 SUPERFAMILY SSF58104 259 486 6.28E-46 T 14-10-2018 TSH58p_10595 ccfaa1977a1034273b1db0253696d03d 492 Pfam PF13188 PAS domain 16 59 0.15 T 14-10-2018 IPR000014 PAS domain TSH58p_10595 ccfaa1977a1034273b1db0253696d03d 492 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 139 249 3.3E-14 T 14-10-2018 IPR000014 PAS domain TSH58p_10595 ccfaa1977a1034273b1db0253696d03d 492 SMART SM00283 258 491 3.0E-28 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_01375 a8b9a7e3c4ac9f6a7ef30d23661afbf3 388 Pfam PF00465 Iron-containing alcohol dehydrogenase 13 378 7.8E-79 T 14-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 TSH58p_01375 a8b9a7e3c4ac9f6a7ef30d23661afbf3 388 Gene3D G3DSA:1.20.1090.10 199 388 2.0E-55 T 14-10-2018 TSH58p_01375 a8b9a7e3c4ac9f6a7ef30d23661afbf3 388 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 273 293 - T 14-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 TSH58p_01375 a8b9a7e3c4ac9f6a7ef30d23661afbf3 388 SUPERFAMILY SSF56796 6 385 3.01E-82 T 14-10-2018 TSH58p_01375 a8b9a7e3c4ac9f6a7ef30d23661afbf3 388 Gene3D G3DSA:3.40.50.1970 3 197 4.2E-37 T 14-10-2018 TSH58p_12355 563a98854915a8861b4b6e44a39511cd 251 SUPERFAMILY SSF81301 21 143 2.62E-11 T 14-10-2018 TSH58p_12355 563a98854915a8861b4b6e44a39511cd 251 Gene3D G3DSA:3.30.460.40 7 136 6.2E-8 T 14-10-2018 TSH58p_06345 85a8cc02b9f81b2cba1a5bf548df8e0e 237 SUPERFAMILY SSF143081 5 220 1.96E-75 T 14-10-2018 IPR036590 SOS response associated peptidase-like TSH58p_06345 85a8cc02b9f81b2cba1a5bf548df8e0e 237 Gene3D G3DSA:3.90.1680.10 3 220 1.5E-71 T 14-10-2018 IPR036590 SOS response associated peptidase-like TSH58p_06345 85a8cc02b9f81b2cba1a5bf548df8e0e 237 Pfam PF02586 SOS response associated peptidase (SRAP) 7 209 2.7E-64 T 14-10-2018 IPR003738 SOS response associated peptidase (SRAP) TSH58p_07775 25265158a9a42ad4f675816e5b48b56c 239 SMART SM00100 21 139 2.6E-19 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_07775 25265158a9a42ad4f675816e5b48b56c 239 Gene3D G3DSA:1.10.10.10 144 237 6.5E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_07775 25265158a9a42ad4f675816e5b48b56c 239 Pfam PF13545 Crp-like helix-turn-helix domain 159 227 1.3E-11 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_07775 25265158a9a42ad4f675816e5b48b56c 239 SMART SM00419 174 221 4.1E-5 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_07775 25265158a9a42ad4f675816e5b48b56c 239 SUPERFAMILY SSF51206 16 152 9.82E-32 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like TSH58p_07775 25265158a9a42ad4f675816e5b48b56c 239 SUPERFAMILY SSF46785 158 230 5.75E-7 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_07775 25265158a9a42ad4f675816e5b48b56c 239 Pfam PF00027 Cyclic nucleotide-binding domain 40 126 9.6E-17 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_07775 25265158a9a42ad4f675816e5b48b56c 239 Gene3D G3DSA:2.60.120.10 8 143 7.2E-34 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_27730 b95525ca14ed3f21cdc64cbc51726d8e 489 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 207 405 7.7E-44 T 14-10-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 TSH58p_27730 b95525ca14ed3f21cdc64cbc51726d8e 489 Gene3D G3DSA:3.40.50.720 5 265 1.5E-53 T 14-10-2018 TSH58p_27730 b95525ca14ed3f21cdc64cbc51726d8e 489 PRINTS PR00084 Mannitol dehydrogenase signature 207 220 6.4E-6 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 TSH58p_27730 b95525ca14ed3f21cdc64cbc51726d8e 489 PRINTS PR00084 Mannitol dehydrogenase signature 20 30 6.4E-6 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 TSH58p_27730 b95525ca14ed3f21cdc64cbc51726d8e 489 PRINTS PR00084 Mannitol dehydrogenase signature 166 179 6.4E-6 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 TSH58p_27730 b95525ca14ed3f21cdc64cbc51726d8e 489 PRINTS PR00084 Mannitol dehydrogenase signature 237 252 6.4E-6 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 TSH58p_27730 b95525ca14ed3f21cdc64cbc51726d8e 489 SUPERFAMILY SSF51735 14 259 7.87E-66 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_27730 b95525ca14ed3f21cdc64cbc51726d8e 489 Gene3D G3DSA:1.10.1040.10 275 478 2.3E-44 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSH58p_27730 b95525ca14ed3f21cdc64cbc51726d8e 489 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 19 174 2.8E-21 T 14-10-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 TSH58p_27730 b95525ca14ed3f21cdc64cbc51726d8e 489 SUPERFAMILY SSF48179 276 473 6.8E-37 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_32145 331eab9433698ed0d45d41337a8333f3 425 Gene3D G3DSA:2.120.10.10 40 273 5.5E-40 T 14-10-2018 TSH58p_32145 331eab9433698ed0d45d41337a8333f3 425 SUPERFAMILY SSF50939 40 414 1.37E-58 T 14-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 TSH58p_32145 331eab9433698ed0d45d41337a8333f3 425 Pfam PF13088 BNR repeat-like domain 55 395 4.3E-71 T 14-10-2018 IPR011040 Sialidase KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 TSH58p_29745 78a0a8a87c0276ed776f23cd372d1d62 271 SUPERFAMILY SSF56300 1 253 3.01E-55 T 14-10-2018 TSH58p_29745 78a0a8a87c0276ed776f23cd372d1d62 271 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 1 256 37.281 T 14-10-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 TSH58p_29745 78a0a8a87c0276ed776f23cd372d1d62 271 Pfam PF00149 Calcineurin-like phosphoesterase 2 198 6.5E-19 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TSH58p_29745 78a0a8a87c0276ed776f23cd372d1d62 271 Gene3D G3DSA:3.60.21.40 1 241 1.8E-80 T 14-10-2018 TSH58p_29745 78a0a8a87c0276ed776f23cd372d1d62 271 Gene3D G3DSA:3.30.750.180 105 232 1.8E-80 T 14-10-2018 TSH58p_14860 b024e7df5c0d529fba6583d46460c127 1806 ProSitePatterns PS00455 Putative AMP-binding domain signature. 410 421 - T 14-10-2018 IPR020845 AMP-binding, conserved site TSH58p_14860 b024e7df5c0d529fba6583d46460c127 1806 Pfam PF00501 AMP-binding enzyme 150 235 8.3E-12 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_14860 b024e7df5c0d529fba6583d46460c127 1806 Pfam PF00501 AMP-binding enzyme 329 702 3.2E-36 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_14860 b024e7df5c0d529fba6583d46460c127 1806 SUPERFAMILY SSF50129 1227 1388 6.35E-21 T 14-10-2018 IPR011032 GroES-like superfamily TSH58p_14860 b024e7df5c0d529fba6583d46460c127 1806 Gene3D G3DSA:3.40.50.12780 319 698 2.4E-39 T 14-10-2018 TSH58p_14860 b024e7df5c0d529fba6583d46460c127 1806 SUPERFAMILY SSF51735 1525 1708 6.27E-7 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_14860 b024e7df5c0d529fba6583d46460c127 1806 SMART SM00829 1220 1684 1.5E-5 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TSH58p_14860 b024e7df5c0d529fba6583d46460c127 1806 Pfam PF00378 Enoyl-CoA hydratase/isomerase 865 1054 8.3E-33 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TSH58p_14860 b024e7df5c0d529fba6583d46460c127 1806 Gene3D G3DSA:3.40.50.720 1523 1708 5.9E-33 T 14-10-2018 TSH58p_14860 b024e7df5c0d529fba6583d46460c127 1806 Gene3D G3DSA:3.40.50.720 1365 1512 6.6E-45 T 14-10-2018 TSH58p_14860 b024e7df5c0d529fba6583d46460c127 1806 Gene3D G3DSA:3.40.50.12780 101 300 2.1E-13 T 14-10-2018 TSH58p_14860 b024e7df5c0d529fba6583d46460c127 1806 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 77 113 4.5E-8 T 14-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 TSH58p_14860 b024e7df5c0d529fba6583d46460c127 1806 SUPERFAMILY SSF51735 1357 1512 1.08E-18 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_14860 b024e7df5c0d529fba6583d46460c127 1806 Gene3D G3DSA:3.30.300.30 699 833 6.2E-21 T 14-10-2018 TSH58p_14860 b024e7df5c0d529fba6583d46460c127 1806 SUPERFAMILY SSF56801 87 823 2.63E-96 T 14-10-2018 TSH58p_14860 b024e7df5c0d529fba6583d46460c127 1806 Pfam PF00107 Zinc-binding dehydrogenase 1395 1512 8.4E-11 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TSH58p_14860 b024e7df5c0d529fba6583d46460c127 1806 Gene3D G3DSA:3.90.226.10 835 1177 4.4E-70 T 14-10-2018 TSH58p_14860 b024e7df5c0d529fba6583d46460c127 1806 Pfam PF13193 AMP-binding enzyme C-terminal domain 727 795 5.7E-13 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSH58p_14860 b024e7df5c0d529fba6583d46460c127 1806 Gene3D G3DSA:3.90.180.10 1231 1364 6.6E-45 T 14-10-2018 TSH58p_14860 b024e7df5c0d529fba6583d46460c127 1806 Gene3D G3DSA:3.90.180.10 1709 1804 1.9E-7 T 14-10-2018 TSH58p_14860 b024e7df5c0d529fba6583d46460c127 1806 SUPERFAMILY SSF52096 863 1077 3.56E-56 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_31310 a204f174da65a6232e3f20c2133bfff3 807 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 415 426 - T 14-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 TSH58p_31310 a204f174da65a6232e3f20c2133bfff3 807 Gene3D G3DSA:3.30.470.20 196 352 7.0E-56 T 14-10-2018 TSH58p_31310 a204f174da65a6232e3f20c2133bfff3 807 Pfam PF00391 PEP-utilising enzyme, mobile domain 385 456 1.0E-25 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TSH58p_31310 a204f174da65a6232e3f20c2133bfff3 807 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 19 343 4.0E-106 T 14-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 TSH58p_31310 a204f174da65a6232e3f20c2133bfff3 807 SUPERFAMILY SSF52009 358 468 1.31E-31 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 TSH58p_31310 a204f174da65a6232e3f20c2133bfff3 807 SUPERFAMILY SSF51621 464 794 1.18E-97 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSH58p_31310 a204f174da65a6232e3f20c2133bfff3 807 Gene3D G3DSA:3.30.1490.20 3 195 3.0E-67 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSH58p_31310 a204f174da65a6232e3f20c2133bfff3 807 PIRSF PIRSF000854 1 796 0.0 T 14-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 TSH58p_31310 a204f174da65a6232e3f20c2133bfff3 807 Gene3D G3DSA:3.50.30.10 373 478 1.1E-38 T 14-10-2018 TSH58p_31310 a204f174da65a6232e3f20c2133bfff3 807 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 6 792 0.0 T 14-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 TSH58p_31310 a204f174da65a6232e3f20c2133bfff3 807 SUPERFAMILY SSF56059 4 385 4.83E-102 T 14-10-2018 TSH58p_31310 a204f174da65a6232e3f20c2133bfff3 807 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 696 714 - T 14-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 TSH58p_31310 a204f174da65a6232e3f20c2133bfff3 807 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 482 789 4.3E-61 T 14-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 TSH58p_31310 a204f174da65a6232e3f20c2133bfff3 807 Gene3D G3DSA:3.20.20.60 479 790 1.8E-101 T 14-10-2018 TSH58p_17040 193fe8cee0626afb368ded8002d8214f 217 Pfam PF01323 DSBA-like thioredoxin domain 3 198 4.5E-38 T 14-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 TSH58p_17040 193fe8cee0626afb368ded8002d8214f 217 SUPERFAMILY SSF52833 2 205 1.48E-44 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_17040 193fe8cee0626afb368ded8002d8214f 217 Gene3D G3DSA:3.40.30.10 1 204 8.8E-65 T 14-10-2018 TSH58p_24765 aca81f01658673e89e8dad4e38887187 160 Pfam PF06793 Uncharacterised protein family (UPF0262) 7 159 4.8E-72 T 14-10-2018 IPR008321 Uncharacterised conserved protein UCP032146 TSH58p_24765 aca81f01658673e89e8dad4e38887187 160 PIRSF PIRSF032146 1 160 1.0E-69 T 14-10-2018 IPR008321 Uncharacterised conserved protein UCP032146 TSH58p_24765 aca81f01658673e89e8dad4e38887187 160 Hamap MF_00678 UPF0262 protein . 6 159 39.979 T 14-10-2018 IPR008321 Uncharacterised conserved protein UCP032146 TSH58p_04710 30ab31a214d3acb072f31199a93814fc 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 5.3E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_04710 30ab31a214d3acb072f31199a93814fc 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 5.3E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_04710 30ab31a214d3acb072f31199a93814fc 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 5.3E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_04710 30ab31a214d3acb072f31199a93814fc 256 SUPERFAMILY SSF51735 5 243 2.57E-58 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_04710 30ab31a214d3acb072f31199a93814fc 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 241 2.8E-38 T 14-10-2018 TSH58p_04710 30ab31a214d3acb072f31199a93814fc 256 Gene3D G3DSA:3.40.50.720 3 254 9.6E-63 T 14-10-2018 TSH58p_04710 30ab31a214d3acb072f31199a93814fc 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 6.0E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_04710 30ab31a214d3acb072f31199a93814fc 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 6.0E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_04710 30ab31a214d3acb072f31199a93814fc 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 6.0E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_04710 30ab31a214d3acb072f31199a93814fc 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.0E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_04710 30ab31a214d3acb072f31199a93814fc 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 6.0E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_24795 1f52cc38da7d1758774cf6a42670ce94 761 SUPERFAMILY SSF51011 603 710 4.6E-25 T 14-10-2018 TSH58p_24795 1f52cc38da7d1758774cf6a42670ce94 761 SUPERFAMILY SSF81296 19 165 1.51E-50 T 14-10-2018 IPR014756 Immunoglobulin E-set TSH58p_24795 1f52cc38da7d1758774cf6a42670ce94 761 Gene3D G3DSA:2.60.40.1180 602 710 1.7E-18 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta TSH58p_24795 1f52cc38da7d1758774cf6a42670ce94 761 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 23 111 5.4E-20 T 14-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 TSH58p_24795 1f52cc38da7d1758774cf6a42670ce94 761 Gene3D G3DSA:3.20.20.80 155 596 2.9E-183 T 14-10-2018 TSH58p_24795 1f52cc38da7d1758774cf6a42670ce94 761 SMART SM00642 176 582 1.8E-8 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSH58p_24795 1f52cc38da7d1758774cf6a42670ce94 761 Gene3D G3DSA:2.60.40.10 9 154 1.2E-52 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_24795 1f52cc38da7d1758774cf6a42670ce94 761 SUPERFAMILY SSF51445 151 591 8.61E-139 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_24795 1f52cc38da7d1758774cf6a42670ce94 761 Pfam PF00128 Alpha amylase, catalytic domain 196 307 1.6E-11 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSH58p_24795 1f52cc38da7d1758774cf6a42670ce94 761 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 19 710 0.0 T 14-10-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 TSH58p_11385 c77b7de46590c72c32d7111d5a3e4a48 161 SUPERFAMILY SSF74942 84 152 2.09E-17 T 14-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily TSH58p_11385 c77b7de46590c72c32d7111d5a3e4a48 161 Pfam PF02576 RimP N-terminal domain 10 83 1.9E-26 T 14-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal TSH58p_11385 c77b7de46590c72c32d7111d5a3e4a48 161 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 5 151 23.988 T 14-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 TSH58p_11385 c77b7de46590c72c32d7111d5a3e4a48 161 SUPERFAMILY SSF75420 4 83 6.28E-23 T 14-10-2018 IPR035956 RimP, N-terminal domain superfamily TSH58p_11385 c77b7de46590c72c32d7111d5a3e4a48 161 Gene3D G3DSA:3.30.300.70 2 80 2.9E-20 T 14-10-2018 IPR035956 RimP, N-terminal domain superfamily TSH58p_11385 c77b7de46590c72c32d7111d5a3e4a48 161 Pfam PF17384 RimP C-terminal SH3 domain 86 150 2.2E-13 T 14-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal TSH58p_23405 9f262a108a4dcaff67c28cbb12b4e939 399 Gene3D G3DSA:2.30.40.20 61 111 2.2E-49 T 14-10-2018 TSH58p_23405 9f262a108a4dcaff67c28cbb12b4e939 399 Gene3D G3DSA:1.10.150.20 207 275 4.8E-16 T 14-10-2018 TSH58p_23405 9f262a108a4dcaff67c28cbb12b4e939 399 SUPERFAMILY SSF56672 43 273 8.45E-77 T 14-10-2018 TSH58p_23405 9f262a108a4dcaff67c28cbb12b4e939 399 Pfam PF11799 impB/mucB/samB family C-terminal domain 273 384 8.9E-19 T 14-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 TSH58p_23405 9f262a108a4dcaff67c28cbb12b4e939 399 SUPERFAMILY SSF100879 280 383 6.28E-26 T 14-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 TSH58p_23405 9f262a108a4dcaff67c28cbb12b4e939 399 Gene3D G3DSA:3.30.70.270 45 203 2.2E-49 T 14-10-2018 TSH58p_23405 9f262a108a4dcaff67c28cbb12b4e939 399 Pfam PF00817 impB/mucB/samB family 47 193 2.8E-43 T 14-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 TSH58p_23405 9f262a108a4dcaff67c28cbb12b4e939 399 Gene3D G3DSA:3.30.1490.100 279 385 1.6E-25 T 14-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 TSH58p_23405 9f262a108a4dcaff67c28cbb12b4e939 399 Hamap MF_01113 DNA polymerase IV [dinB]. 41 389 33.953 T 14-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 TSH58p_12935 7a616abf0b0dede59082b3bd84c13975 220 Gene3D G3DSA:3.40.50.300 22 218 8.6E-59 T 14-10-2018 TSH58p_12935 7a616abf0b0dede59082b3bd84c13975 220 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 47 192 3.1E-14 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSH58p_12935 7a616abf0b0dede59082b3bd84c13975 220 Pfam PF01926 50S ribosome-binding GTPase 47 165 8.6E-24 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 TSH58p_12935 7a616abf0b0dede59082b3bd84c13975 220 SUPERFAMILY SSF52540 28 216 8.75E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_12935 7a616abf0b0dede59082b3bd84c13975 220 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 33 217 27.986 T 14-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 TSH58p_12935 7a616abf0b0dede59082b3bd84c13975 220 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 29 213 1.3E-67 T 14-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 TSH58p_31555 9c3570be8b776662b11f55b9f599350e 319 Pfam PF03069 Acetamidase/Formamidase family 71 160 8.0E-11 T 14-10-2018 IPR004304 Acetamidase/Formamidase GO:0016811 TSH58p_31555 9c3570be8b776662b11f55b9f599350e 319 Pfam PF03069 Acetamidase/Formamidase family 170 301 7.3E-20 T 14-10-2018 IPR004304 Acetamidase/Formamidase GO:0016811 TSH58p_31555 9c3570be8b776662b11f55b9f599350e 319 Gene3D G3DSA:2.60.120.580 8 141 1.4E-15 T 14-10-2018 TSH58p_31555 9c3570be8b776662b11f55b9f599350e 319 Gene3D G3DSA:2.60.120.580 143 235 5.4E-30 T 14-10-2018 TSH58p_31555 9c3570be8b776662b11f55b9f599350e 319 Gene3D G3DSA:3.10.28.20 238 318 5.0E-24 T 14-10-2018 TSH58p_31555 9c3570be8b776662b11f55b9f599350e 319 SUPERFAMILY SSF141130 8 315 6.67E-89 T 14-10-2018 TSH58p_21320 fb90acef1544cd0d5d283f29685886b5 311 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 1 117 1.6E-47 T 14-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TSH58p_21320 fb90acef1544cd0d5d283f29685886b5 311 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 125 140 - T 14-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 TSH58p_21320 fb90acef1544cd0d5d283f29685886b5 311 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 1 311 48.088 T 14-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 TSH58p_21320 fb90acef1544cd0d5d283f29685886b5 311 SUPERFAMILY SSF53271 66 301 4.04E-62 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like TSH58p_21320 fb90acef1544cd0d5d283f29685886b5 311 Pfam PF14572 Phosphoribosyl synthetase-associated domain 202 310 1.3E-19 T 14-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TSH58p_21320 fb90acef1544cd0d5d283f29685886b5 311 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 1 311 5.9E-113 T 14-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TSH58p_21320 fb90acef1544cd0d5d283f29685886b5 311 Gene3D G3DSA:3.40.50.2020 5 299 5.7E-120 T 14-10-2018 TSH58p_21320 fb90acef1544cd0d5d283f29685886b5 311 Gene3D G3DSA:3.40.50.2020 144 287 5.7E-120 T 14-10-2018 TSH58p_21320 fb90acef1544cd0d5d283f29685886b5 311 SMART SM01400 1 117 4.1E-78 T 14-10-2018 TSH58p_06245 291b06024d97e296437c69d177efa72c 141 ProDom PD085709 MEMBRANE RP436 UNCHARACTERIZED INTEGRAL PREDICTED TRANSMEMBRANE 7 119 2.0E-6 T 14-10-2018 IPR020143 Uncharacterised protein family, RP436 TSH58p_06245 291b06024d97e296437c69d177efa72c 141 Pfam PF09335 SNARE associated Golgi protein 25 140 5.8E-12 T 14-10-2018 IPR032816 SNARE associated Golgi protein TSH58p_03125 10fd5fdae0de8d569646c7514d7989df 211 SUPERFAMILY SSF53335 7 205 4.41E-35 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_03125 10fd5fdae0de8d569646c7514d7989df 211 Pfam PF08241 Methyltransferase domain 45 140 2.1E-21 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TSH58p_03125 10fd5fdae0de8d569646c7514d7989df 211 Gene3D G3DSA:3.40.50.150 1 196 2.0E-32 T 14-10-2018 TSH58p_09445 2f0d3931f14513824c4aa493c5ab9be2 416 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 TSH58p_09445 2f0d3931f14513824c4aa493c5ab9be2 416 Gene3D G3DSA:3.30.559.10 184 416 1.1E-97 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TSH58p_09445 2f0d3931f14513824c4aa493c5ab9be2 416 Gene3D G3DSA:4.10.320.10 111 155 2.0E-14 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TSH58p_09445 2f0d3931f14513824c4aa493c5ab9be2 416 SUPERFAMILY SSF47005 116 154 1.31E-10 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TSH58p_09445 2f0d3931f14513824c4aa493c5ab9be2 416 SUPERFAMILY SSF52777 186 415 3.69E-91 T 14-10-2018 TSH58p_09445 2f0d3931f14513824c4aa493c5ab9be2 416 Gene3D G3DSA:2.40.50.100 1 101 6.9E-27 T 14-10-2018 TSH58p_09445 2f0d3931f14513824c4aa493c5ab9be2 416 Pfam PF00364 Biotin-requiring enzyme 4 75 2.5E-21 T 14-10-2018 IPR000089 Biotin/lipoyl attachment TSH58p_09445 2f0d3931f14513824c4aa493c5ab9be2 416 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 4 416 7.7E-181 T 14-10-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 TSH58p_09445 2f0d3931f14513824c4aa493c5ab9be2 416 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 186 414 8.0E-84 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 TSH58p_09445 2f0d3931f14513824c4aa493c5ab9be2 416 Pfam PF02817 e3 binding domain 117 149 1.3E-12 T 14-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 TSH58p_09445 2f0d3931f14513824c4aa493c5ab9be2 416 SUPERFAMILY SSF51230 1 96 4.45E-28 T 14-10-2018 IPR011053 Single hybrid motif TSH58p_32005 db9ff96f210725682e1f9d8739f805b0 181 Gene3D G3DSA:1.20.120.520 2 163 2.4E-18 T 14-10-2018 TSH58p_32005 db9ff96f210725682e1f9d8739f805b0 181 Pfam PF01814 Hemerythrin HHE cation binding domain 10 145 9.6E-16 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 TSH58p_05870 d2daa68d2c2da3492639a0227a430ebc 204 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 18 168 4.1E-37 T 14-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05870 d2daa68d2c2da3492639a0227a430ebc 204 Gene3D G3DSA:1.20.120.1200 5 170 5.9E-42 T 14-10-2018 TSH58p_10510 9f4f73d4b45afde002d35a0b1827a63e 573 SUPERFAMILY SSF52922 469 567 2.43E-15 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSH58p_10510 9f4f73d4b45afde002d35a0b1827a63e 573 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 212 446 1.7E-51 T 14-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TSH58p_10510 9f4f73d4b45afde002d35a0b1827a63e 573 Gene3D G3DSA:3.40.920.10 2 181 1.2E-21 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TSH58p_10510 9f4f73d4b45afde002d35a0b1827a63e 573 Gene3D G3DSA:3.40.50.970 189 385 4.5E-62 T 14-10-2018 TSH58p_10510 9f4f73d4b45afde002d35a0b1827a63e 573 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 14 175 1.2E-22 T 14-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TSH58p_10510 9f4f73d4b45afde002d35a0b1827a63e 573 SUPERFAMILY SSF53323 6 222 2.62E-24 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TSH58p_10510 9f4f73d4b45afde002d35a0b1827a63e 573 Gene3D G3DSA:3.40.50.920 466 572 9.7E-18 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSH58p_10510 9f4f73d4b45afde002d35a0b1827a63e 573 SUPERFAMILY SSF52518 200 454 8.1E-58 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_10510 9f4f73d4b45afde002d35a0b1827a63e 573 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 6 568 5.5E-165 T 14-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 TSH58p_10495 846d066da0cea0d6071f3e6e647bbae3 564 Pfam PF12450 von Willebrand factor 88 177 6.4E-29 T 14-10-2018 IPR022156 Uncharacterised protein YfbK, N-terminal TSH58p_10495 846d066da0cea0d6071f3e6e647bbae3 564 Pfam PF12034 Domain of unknown function (DUF3520) 370 558 5.8E-60 T 14-10-2018 IPR021908 Protein of unknown function DUF3520 TSH58p_10495 846d066da0cea0d6071f3e6e647bbae3 564 SUPERFAMILY SSF53300 190 366 5.11E-34 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TSH58p_10495 846d066da0cea0d6071f3e6e647bbae3 564 Gene3D G3DSA:3.40.50.410 193 372 1.7E-30 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TSH58p_10495 846d066da0cea0d6071f3e6e647bbae3 564 SMART SM00327 192 367 2.3E-23 T 14-10-2018 IPR002035 von Willebrand factor, type A TSH58p_10495 846d066da0cea0d6071f3e6e647bbae3 564 Pfam PF00092 von Willebrand factor type A domain 194 354 1.8E-16 T 14-10-2018 IPR002035 von Willebrand factor, type A TSH58p_14920 e927572b9d96d8397d88052e1c0f91e5 383 Gene3D G3DSA:3.30.360.10 141 381 2.2E-71 T 14-10-2018 TSH58p_14920 e927572b9d96d8397d88052e1c0f91e5 383 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 50 135 4.0E-11 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 TSH58p_14920 e927572b9d96d8397d88052e1c0f91e5 383 SUPERFAMILY SSF51735 50 173 4.66E-30 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_14920 e927572b9d96d8397d88052e1c0f91e5 383 SUPERFAMILY SSF55347 146 346 3.11E-34 T 14-10-2018 TSH58p_14920 e927572b9d96d8397d88052e1c0f91e5 383 Gene3D G3DSA:3.40.50.720 1 140 3.2E-40 T 14-10-2018 TSH58p_22495 c2e08ede713a7493c3e3a7f432bce675 364 Gene3D G3DSA:3.20.20.300 19 351 6.9E-87 T 14-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 TSH58p_22495 c2e08ede713a7493c3e3a7f432bce675 364 SUPERFAMILY SSF51445 29 318 1.47E-62 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_22495 c2e08ede713a7493c3e3a7f432bce675 364 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 53 322 1.3E-46 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TSH58p_25410 700b5d2bb3fed66b21418a7c4e309f0f 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 1.2E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_25410 700b5d2bb3fed66b21418a7c4e309f0f 301 Gene3D G3DSA:1.10.10.10 4 93 9.2E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_25410 700b5d2bb3fed66b21418a7c4e309f0f 301 Pfam PF03466 LysR substrate binding domain 90 293 4.8E-40 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_25410 700b5d2bb3fed66b21418a7c4e309f0f 301 SUPERFAMILY SSF53850 91 295 3.57E-44 T 14-10-2018 TSH58p_25410 700b5d2bb3fed66b21418a7c4e309f0f 301 Gene3D G3DSA:3.40.190.10 166 268 6.2E-58 T 14-10-2018 TSH58p_25410 700b5d2bb3fed66b21418a7c4e309f0f 301 SUPERFAMILY SSF46785 5 113 4.74E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_25410 700b5d2bb3fed66b21418a7c4e309f0f 301 Gene3D G3DSA:3.40.190.10 94 292 6.2E-58 T 14-10-2018 TSH58p_01230 89bff64a71e41258f648fbd3895db3ad 332 Pfam PF02655 ATP-grasp domain 123 290 2.2E-27 T 14-10-2018 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 TSH58p_01230 89bff64a71e41258f648fbd3895db3ad 332 SUPERFAMILY SSF56059 121 319 4.95E-22 T 14-10-2018 TSH58p_01230 89bff64a71e41258f648fbd3895db3ad 332 Gene3D G3DSA:3.30.470.20 119 303 2.0E-27 T 14-10-2018 TSH58p_01230 89bff64a71e41258f648fbd3895db3ad 332 Gene3D G3DSA:3.30.1490.350 144 200 2.0E-27 T 14-10-2018 TSH58p_01230 89bff64a71e41258f648fbd3895db3ad 332 PIRSF PIRSF016766 1 319 1.7E-68 T 14-10-2018 IPR024710 Tyramine--L-glutamate ligase KEGG: 00680+6.3.4.24|MetaCyc: PWY-5254 TSH58p_19885 4ba09d492addb5d61155a55e70947773 141 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 12 129 5.8E-19 T 14-10-2018 IPR000014 PAS domain TSH58p_19885 4ba09d492addb5d61155a55e70947773 141 Gene3D G3DSA:3.30.450.20 10 140 2.8E-26 T 14-10-2018 TSH58p_19885 4ba09d492addb5d61155a55e70947773 141 SUPERFAMILY SSF55785 19 136 7.82E-25 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_19885 4ba09d492addb5d61155a55e70947773 141 Pfam PF13426 PAS domain 20 126 8.7E-15 T 14-10-2018 IPR000014 PAS domain TSH58p_19885 4ba09d492addb5d61155a55e70947773 141 SMART SM00091 8 74 1.4E-8 T 14-10-2018 IPR000014 PAS domain TSH58p_25200 b03446b706231e9cc981fbfb56b48140 406 SUPERFAMILY SSF56059 127 328 3.36E-22 T 14-10-2018 TSH58p_25200 b03446b706231e9cc981fbfb56b48140 406 Gene3D G3DSA:3.30.470.20 120 377 2.4E-15 T 14-10-2018 TSH58p_25855 d6a8f593bf1224acb7b0fbc689a3bf05 208 Gene3D G3DSA:3.30.420.10 15 191 4.2E-45 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TSH58p_25855 d6a8f593bf1224acb7b0fbc689a3bf05 208 Pfam PF01612 3'-5' exonuclease 18 173 2.7E-37 T 14-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 TSH58p_25855 d6a8f593bf1224acb7b0fbc689a3bf05 208 SMART SM00474 1 174 4.2E-41 T 14-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 TSH58p_25855 d6a8f593bf1224acb7b0fbc689a3bf05 208 SUPERFAMILY SSF53098 18 195 9.7E-53 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily TSH58p_05400 ba84e1531f7754df954eee4435d449ec 702 SUPERFAMILY SSF55874 394 540 7.86E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_05400 ba84e1531f7754df954eee4435d449ec 702 Gene3D G3DSA:3.30.450.20 64 186 6.8E-6 T 14-10-2018 TSH58p_05400 ba84e1531f7754df954eee4435d449ec 702 Gene3D G3DSA:3.30.565.10 393 550 4.9E-40 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_05400 ba84e1531f7754df954eee4435d449ec 702 Pfam PF00072 Response regulator receiver domain 576 657 2.0E-14 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_05400 ba84e1531f7754df954eee4435d449ec 702 SUPERFAMILY SSF52172 575 701 9.11E-25 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_05400 ba84e1531f7754df954eee4435d449ec 702 Gene3D G3DSA:1.10.287.130 317 388 1.8E-19 T 14-10-2018 TSH58p_05400 ba84e1531f7754df954eee4435d449ec 702 Pfam PF00512 His Kinase A (phospho-acceptor) domain 327 389 2.9E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_05400 ba84e1531f7754df954eee4435d449ec 702 PRINTS PR00344 Bacterial sensor protein C-terminal signature 489 499 1.0E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_05400 ba84e1531f7754df954eee4435d449ec 702 PRINTS PR00344 Bacterial sensor protein C-terminal signature 471 485 1.0E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_05400 ba84e1531f7754df954eee4435d449ec 702 PRINTS PR00344 Bacterial sensor protein C-terminal signature 502 520 1.0E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_05400 ba84e1531f7754df954eee4435d449ec 702 PRINTS PR00344 Bacterial sensor protein C-terminal signature 526 539 1.0E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_05400 ba84e1531f7754df954eee4435d449ec 702 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 434 541 1.5E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_05400 ba84e1531f7754df954eee4435d449ec 702 Gene3D G3DSA:3.30.450.20 187 308 3.5E-13 T 14-10-2018 TSH58p_05400 ba84e1531f7754df954eee4435d449ec 702 SUPERFAMILY SSF55785 182 308 2.47E-14 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_05400 ba84e1531f7754df954eee4435d449ec 702 Pfam PF12860 PAS fold 78 189 6.4E-18 T 14-10-2018 TSH58p_05400 ba84e1531f7754df954eee4435d449ec 702 SMART SM00388 325 391 3.9E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_05400 ba84e1531f7754df954eee4435d449ec 702 Gene3D G3DSA:3.40.50.2300 571 702 7.2E-25 T 14-10-2018 TSH58p_05400 ba84e1531f7754df954eee4435d449ec 702 SMART SM00387 433 542 5.0E-33 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_05400 ba84e1531f7754df954eee4435d449ec 702 SUPERFAMILY SSF55785 80 192 1.39E-5 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_05400 ba84e1531f7754df954eee4435d449ec 702 Pfam PF13188 PAS domain 197 244 1.7E-6 T 14-10-2018 IPR000014 PAS domain TSH58p_05400 ba84e1531f7754df954eee4435d449ec 702 SMART SM00448 574 697 1.7E-13 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_05400 ba84e1531f7754df954eee4435d449ec 702 SUPERFAMILY SSF47384 316 389 1.0E-11 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_01170 6eecf5461c0a791f6ec234f9dfb83e87 299 Gene3D G3DSA:3.30.70.520 3 296 2.7E-120 T 14-10-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like superfamily TSH58p_01170 6eecf5461c0a791f6ec234f9dfb83e87 299 Gene3D G3DSA:3.30.70.520 17 161 2.7E-120 T 14-10-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like superfamily TSH58p_01170 6eecf5461c0a791f6ec234f9dfb83e87 299 TIGRFAM TIGR03119 one_C_fhcD: formylmethanofuran--tetrahydromethanopterin N-formyltransferase 8 297 1.0E-124 T 14-10-2018 IPR014053 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr GO:0006730|GO:0030270 TSH58p_01170 6eecf5461c0a791f6ec234f9dfb83e87 299 Pfam PF02741 FTR, proximal lobe 146 297 7.9E-61 T 14-10-2018 IPR002770 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, C-terminal GO:0006730|GO:0016740 TSH58p_01170 6eecf5461c0a791f6ec234f9dfb83e87 299 SUPERFAMILY SSF55112 145 298 2.04E-55 T 14-10-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like superfamily TSH58p_01170 6eecf5461c0a791f6ec234f9dfb83e87 299 Pfam PF01913 Formylmethanofuran-tetrahydromethanopterin formyltransferase 1 143 6.2E-62 T 14-10-2018 IPR022667 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, N-terminal GO:0006730|GO:0016740 TSH58p_01170 6eecf5461c0a791f6ec234f9dfb83e87 299 PIRSF PIRSF006414 1 299 1.5E-116 T 14-10-2018 IPR014053 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr GO:0006730|GO:0030270 TSH58p_01170 6eecf5461c0a791f6ec234f9dfb83e87 299 Hamap MF_00579 Formylmethanofuran--tetrahydromethanopterin formyltransferase [ftr]. 1 298 46.017 T 14-10-2018 IPR014053 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr GO:0006730|GO:0030270 TSH58p_01170 6eecf5461c0a791f6ec234f9dfb83e87 299 SUPERFAMILY SSF55112 1 144 1.96E-60 T 14-10-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like superfamily TSH58p_31865 0cd0dff0a59e606a30a1bafe860f825f 285 SUPERFAMILY SSF56655 26 280 8.51E-70 T 14-10-2018 TSH58p_31865 0cd0dff0a59e606a30a1bafe860f825f 285 Pfam PF00459 Inositol monophosphatase family 27 281 8.0E-47 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_31865 0cd0dff0a59e606a30a1bafe860f825f 285 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 101 114 - T 14-10-2018 IPR020583 Inositol monophosphatase, metal-binding site TSH58p_31865 0cd0dff0a59e606a30a1bafe860f825f 285 Gene3D G3DSA:3.40.190.80 166 281 2.2E-33 T 14-10-2018 TSH58p_31865 0cd0dff0a59e606a30a1bafe860f825f 285 TIGRFAM TIGR02067 his_9_HisN: histidinol-phosphatase 29 280 2.3E-86 T 14-10-2018 IPR011809 Histidinol-phosphate phosphatase, putative, inositol monophosphatase GO:0004401 KEGG: 00340+3.1.3.15 TSH58p_31865 0cd0dff0a59e606a30a1bafe860f825f 285 PRINTS PR00377 Inositol monophosphatase superfamily signature 229 253 1.6E-18 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_31865 0cd0dff0a59e606a30a1bafe860f825f 285 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 1.6E-18 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_31865 0cd0dff0a59e606a30a1bafe860f825f 285 PRINTS PR00377 Inositol monophosphatase superfamily signature 198 219 1.6E-18 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_31865 0cd0dff0a59e606a30a1bafe860f825f 285 PRINTS PR00377 Inositol monophosphatase superfamily signature 59 79 1.6E-18 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_31865 0cd0dff0a59e606a30a1bafe860f825f 285 PRINTS PR00377 Inositol monophosphatase superfamily signature 101 117 1.6E-18 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_31865 0cd0dff0a59e606a30a1bafe860f825f 285 Gene3D G3DSA:3.30.540.10 23 158 7.8E-39 T 14-10-2018 TSH58p_06220 f48b3b81a359c2ca7e3d8973a6e28f79 339 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 7 319 36.191 T 14-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_06220 f48b3b81a359c2ca7e3d8973a6e28f79 339 SUPERFAMILY SSF55257 15 237 1.12E-28 T 14-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_06220 f48b3b81a359c2ca7e3d8973a6e28f79 339 Gene3D G3DSA:1.10.150.20 246 331 1.0E-37 T 14-10-2018 TSH58p_06220 f48b3b81a359c2ca7e3d8973a6e28f79 339 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 67 159 6.2E-22 T 14-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_06220 f48b3b81a359c2ca7e3d8973a6e28f79 339 SUPERFAMILY SSF56553 57 178 3.01E-41 T 14-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_06220 f48b3b81a359c2ca7e3d8973a6e28f79 339 Gene3D G3DSA:2.170.120.12 57 177 6.1E-82 T 14-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_06220 f48b3b81a359c2ca7e3d8973a6e28f79 339 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 33 228 3.3E-22 T 14-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_06220 f48b3b81a359c2ca7e3d8973a6e28f79 339 SUPERFAMILY SSF47789 252 328 1.44E-27 T 14-10-2018 TSH58p_06220 f48b3b81a359c2ca7e3d8973a6e28f79 339 Gene3D G3DSA:3.30.1360.10 25 228 6.1E-82 T 14-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_06220 f48b3b81a359c2ca7e3d8973a6e28f79 339 SMART SM00662 27 234 3.2E-89 T 14-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_06220 f48b3b81a359c2ca7e3d8973a6e28f79 339 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 259 318 2.0E-27 T 14-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_06220 f48b3b81a359c2ca7e3d8973a6e28f79 339 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 251 310 9.0E-26 T 14-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_06220 f48b3b81a359c2ca7e3d8973a6e28f79 339 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 28 319 1.1E-114 T 14-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_18820 87c352643fb2cf40a6513248626838df 266 SUPERFAMILY SSF53850 31 266 9.62E-90 T 14-10-2018 TSH58p_18820 87c352643fb2cf40a6513248626838df 266 Pfam PF03180 NLPA lipoprotein 31 266 4.4E-100 T 14-10-2018 IPR004872 Lipoprotein NlpA family TSH58p_18820 87c352643fb2cf40a6513248626838df 266 Gene3D G3DSA:3.40.190.10 112 216 1.6E-103 T 14-10-2018 TSH58p_18820 87c352643fb2cf40a6513248626838df 266 PIRSF PIRSF002854 2 266 5.7E-108 T 14-10-2018 IPR004872 Lipoprotein NlpA family TSH58p_18820 87c352643fb2cf40a6513248626838df 266 Gene3D G3DSA:3.40.190.10 31 263 1.6E-103 T 14-10-2018 TSH58p_18820 87c352643fb2cf40a6513248626838df 266 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 27 266 2.4E-82 T 14-10-2018 IPR004872 Lipoprotein NlpA family TSH58p_24530 f3bfa807a95deca31e95ffa10ff4d174 695 Pfam PF04632 Fusaric acid resistance protein family 14 676 2.6E-194 T 14-10-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0022857|GO:0055085 TSH58p_03055 adc44058c9dc1f2d742c35afba4860eb 379 Gene3D G3DSA:3.40.50.150 174 355 9.3E-101 T 14-10-2018 TSH58p_03055 adc44058c9dc1f2d742c35afba4860eb 379 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 200 211 - T 14-10-2018 IPR000241 Putative RNA methylase domain TSH58p_03055 adc44058c9dc1f2d742c35afba4860eb 379 SUPERFAMILY SSF53335 146 349 8.9E-36 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_03055 adc44058c9dc1f2d742c35afba4860eb 379 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 198 212 7.6E-5 T 14-10-2018 TSH58p_03055 adc44058c9dc1f2d742c35afba4860eb 379 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 300 312 7.6E-5 T 14-10-2018 TSH58p_03055 adc44058c9dc1f2d742c35afba4860eb 379 Gene3D G3DSA:3.30.2130.30 17 254 9.3E-101 T 14-10-2018 TSH58p_03055 adc44058c9dc1f2d742c35afba4860eb 379 Pfam PF01170 Putative RNA methylase family UPF0020 167 351 2.7E-39 T 14-10-2018 IPR000241 Putative RNA methylase domain TSH58p_00990 dfb598f14976bd1156bbc6ec9ee719c1 271 SUPERFAMILY SSF52096 13 271 3.95E-64 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_00990 dfb598f14976bd1156bbc6ec9ee719c1 271 Pfam PF00378 Enoyl-CoA hydratase/isomerase 20 270 1.5E-38 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TSH58p_00990 dfb598f14976bd1156bbc6ec9ee719c1 271 Gene3D G3DSA:3.90.226.10 10 271 2.0E-63 T 14-10-2018 TSH58p_13275 83e64dc71ba732a81c225e30909aeb9f 211 SUPERFAMILY SSF52833 1 83 3.34E-25 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_13275 83e64dc71ba732a81c225e30909aeb9f 211 Gene3D G3DSA:1.20.1050.10 82 194 3.0E-67 T 14-10-2018 TSH58p_13275 83e64dc71ba732a81c225e30909aeb9f 211 SUPERFAMILY SSF47616 80 204 2.92E-24 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily TSH58p_13275 83e64dc71ba732a81c225e30909aeb9f 211 Pfam PF02798 Glutathione S-transferase, N-terminal domain 2 72 1.3E-17 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 TSH58p_13275 83e64dc71ba732a81c225e30909aeb9f 211 Gene3D G3DSA:3.40.30.10 4 202 3.0E-67 T 14-10-2018 TSH58p_13275 83e64dc71ba732a81c225e30909aeb9f 211 Pfam PF14497 Glutathione S-transferase, C-terminal domain 110 199 9.7E-7 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal TSH58p_07160 4ba686e175d3113d8eba83fe75c27045 865 Gene3D G3DSA:2.60.120.200 434 635 2.4E-6 T 14-10-2018 TSH58p_07160 4ba686e175d3113d8eba83fe75c27045 865 SUPERFAMILY SSF49899 476 606 1.97E-5 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily TSH58p_07850 1a98c8e2601da75db23f71d3a84cdced 332 Gene3D G3DSA:3.20.20.120 110 332 9.0E-60 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TSH58p_07850 1a98c8e2601da75db23f71d3a84cdced 332 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 177 208 - T 14-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 TSH58p_07850 1a98c8e2601da75db23f71d3a84cdced 332 SUPERFAMILY SSF54826 6 116 8.42E-28 T 14-10-2018 TSH58p_07850 1a98c8e2601da75db23f71d3a84cdced 332 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 8 116 1.4E-9 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain TSH58p_07850 1a98c8e2601da75db23f71d3a84cdced 332 SMART SM00922 135 227 4.9E-19 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal TSH58p_07850 1a98c8e2601da75db23f71d3a84cdced 332 Gene3D G3DSA:3.30.390.10 3 108 1.1E-28 T 14-10-2018 IPR029017 Enolase-like, N-terminal TSH58p_07850 1a98c8e2601da75db23f71d3a84cdced 332 Pfam PF13378 Enolase C-terminal domain-like 138 297 4.3E-28 T 14-10-2018 IPR029065 Enolase C-terminal domain-like TSH58p_07850 1a98c8e2601da75db23f71d3a84cdced 332 SUPERFAMILY SSF51604 122 332 4.98E-54 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TSH58p_07715 8e7869892ee384039b67df1b475eb3ec 305 SUPERFAMILY SSF117916 223 297 1.11E-19 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TSH58p_07715 8e7869892ee384039b67df1b475eb3ec 305 PIRSF PIRSF000375 1 299 2.7E-135 T 14-10-2018 IPR016217 Nitrogen fixation, NifU TSH58p_07715 8e7869892ee384039b67df1b475eb3ec 305 Pfam PF01592 NifU-like N terminal domain 4 124 4.5E-51 T 14-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 TSH58p_07715 8e7869892ee384039b67df1b475eb3ec 305 Pfam PF04324 BFD-like [2Fe-2S] binding domain 135 184 1.8E-16 T 14-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain TSH58p_07715 8e7869892ee384039b67df1b475eb3ec 305 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 237 299 8.0E-29 T 14-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 TSH58p_07715 8e7869892ee384039b67df1b475eb3ec 305 Gene3D G3DSA:3.90.1010.10 1 135 4.8E-55 T 14-10-2018 TSH58p_07715 8e7869892ee384039b67df1b475eb3ec 305 SUPERFAMILY SSF82649 2 131 1.75E-43 T 14-10-2018 TSH58p_07715 8e7869892ee384039b67df1b475eb3ec 305 Pfam PF01106 NifU-like domain 235 295 4.1E-21 T 14-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 TSH58p_07715 8e7869892ee384039b67df1b475eb3ec 305 Gene3D G3DSA:1.10.10.1100 136 190 7.8E-7 T 14-10-2018 TSH58p_07715 8e7869892ee384039b67df1b475eb3ec 305 Gene3D G3DSA:3.30.300.130 227 299 8.7E-20 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TSH58p_07715 8e7869892ee384039b67df1b475eb3ec 305 TIGRFAM TIGR02000 NifU_proper: Fe-S cluster assembly protein NifU 1 298 4.5E-154 T 14-10-2018 IPR010238 NIF system FeS cluster assembly, NifU GO:0005506|GO:0016226|GO:0051536 TSH58p_25840 07a16f68d8c8c140ed743f480ce871b0 391 Pfam PF07690 Major Facilitator Superfamily 26 205 6.4E-10 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_25840 07a16f68d8c8c140ed743f480ce871b0 391 Gene3D G3DSA:1.20.1250.20 21 205 3.8E-11 T 14-10-2018 TSH58p_25840 07a16f68d8c8c140ed743f480ce871b0 391 Gene3D G3DSA:1.20.1250.20 208 386 8.0E-21 T 14-10-2018 TSH58p_25840 07a16f68d8c8c140ed743f480ce871b0 391 SUPERFAMILY SSF103473 22 383 5.23E-38 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_10950 30d604ad02f78051688cf99022d14b0f 173 Pfam PF03734 L,D-transpeptidase catalytic domain 22 165 1.4E-9 T 14-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 TSH58p_22105 6e931d2f752ef27731808c647285173c 675 Gene3D G3DSA:1.25.40.10 446 674 2.5E-14 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_22105 6e931d2f752ef27731808c647285173c 675 Gene3D G3DSA:1.25.40.10 296 439 2.4E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_22105 6e931d2f752ef27731808c647285173c 675 SUPERFAMILY SSF48452 401 637 3.58E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_22105 6e931d2f752ef27731808c647285173c 675 SUPERFAMILY SSF48452 271 436 2.66E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_03925 8965d5a384fa7d2638469781566693e1 614 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 1 614 33.872 T 14-10-2018 IPR023051 Potassium uptake protein, low affinity, Kup TSH58p_03925 8965d5a384fa7d2638469781566693e1 614 Pfam PF02705 K+ potassium transporter 6 536 1.1E-210 T 14-10-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 TSH58p_13765 285c84027d5621668bfb2235875f6dc6 271 Pfam PF07859 alpha/beta hydrolase fold 65 175 9.2E-15 T 14-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 TSH58p_13765 285c84027d5621668bfb2235875f6dc6 271 Gene3D G3DSA:3.40.50.1820 22 266 2.7E-53 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_13765 285c84027d5621668bfb2235875f6dc6 271 SUPERFAMILY SSF53474 6 268 6.05E-44 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_13765 285c84027d5621668bfb2235875f6dc6 271 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 129 144 - T 14-10-2018 IPR019826 Carboxylesterase type B, active site TSH58p_16520 24df4c3dec1b47bea8271e0d9e00eec8 398 SMART SM00833 298 392 5.6E-18 T 14-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal TSH58p_16520 24df4c3dec1b47bea8271e0d9e00eec8 398 SUPERFAMILY SSF52540 24 216 2.31E-35 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_16520 24df4c3dec1b47bea8271e0d9e00eec8 398 SUPERFAMILY SSF90002 298 392 3.79E-21 T 14-10-2018 TSH58p_16520 24df4c3dec1b47bea8271e0d9e00eec8 398 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 298 391 1.5E-17 T 14-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal TSH58p_16520 24df4c3dec1b47bea8271e0d9e00eec8 398 Gene3D G3DSA:3.30.1220.10 282 391 9.9E-24 T 14-10-2018 IPR036627 CobW-like, C-terminal domain superfamily TSH58p_16520 24df4c3dec1b47bea8271e0d9e00eec8 398 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 26 206 9.8E-46 T 14-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain TSH58p_16520 24df4c3dec1b47bea8271e0d9e00eec8 398 Gene3D G3DSA:3.40.50.300 23 226 1.3E-62 T 14-10-2018 TSH58p_11525 c1bdaaed752a2bdfed56dedfbd456d41 280 Gene3D G3DSA:3.20.190.10 1 135 1.1E-36 T 14-10-2018 IPR035937 MutM-like, N-terminal TSH58p_11525 c1bdaaed752a2bdfed56dedfbd456d41 280 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 279 1.7E-85 T 14-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 TSH58p_11525 c1bdaaed752a2bdfed56dedfbd456d41 280 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 280 40.751 T 14-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 TSH58p_11525 c1bdaaed752a2bdfed56dedfbd456d41 280 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 134 223 1.8E-24 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 TSH58p_11525 c1bdaaed752a2bdfed56dedfbd456d41 280 Gene3D G3DSA:1.10.8.50 145 280 1.8E-45 T 14-10-2018 TSH58p_11525 c1bdaaed752a2bdfed56dedfbd456d41 280 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 117 6.9E-36 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 TSH58p_11525 c1bdaaed752a2bdfed56dedfbd456d41 280 SUPERFAMILY SSF57716 222 279 5.42E-13 T 14-10-2018 TSH58p_11525 c1bdaaed752a2bdfed56dedfbd456d41 280 SMART SM01232 134 226 9.7E-47 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 TSH58p_11525 c1bdaaed752a2bdfed56dedfbd456d41 280 SUPERFAMILY SSF81624 2 139 6.8E-39 T 14-10-2018 IPR035937 MutM-like, N-terminal TSH58p_11525 c1bdaaed752a2bdfed56dedfbd456d41 280 SUPERFAMILY SSF46946 134 222 1.05E-27 T 14-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 TSH58p_11525 c1bdaaed752a2bdfed56dedfbd456d41 280 SMART SM00898 2 118 5.4E-49 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 TSH58p_07440 43b84e44095267b8503fa29d853a7833 414 SUPERFAMILY SSF81901 180 408 8.29E-57 T 14-10-2018 TSH58p_07440 43b84e44095267b8503fa29d853a7833 414 Gene3D G3DSA:1.25.40.10 254 413 7.8E-52 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_07440 43b84e44095267b8503fa29d853a7833 414 Gene3D G3DSA:1.25.40.10 113 253 1.7E-40 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_07440 43b84e44095267b8503fa29d853a7833 414 SMART SM00671 183 218 1.3E-5 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07440 43b84e44095267b8503fa29d853a7833 414 SMART SM00671 291 326 1.0E-5 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07440 43b84e44095267b8503fa29d853a7833 414 SMART SM00671 255 290 1.7E-8 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07440 43b84e44095267b8503fa29d853a7833 414 SMART SM00671 147 182 1.4E-5 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07440 43b84e44095267b8503fa29d853a7833 414 SMART SM00671 110 146 1.7 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07440 43b84e44095267b8503fa29d853a7833 414 SMART SM00671 363 398 8.4E-8 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07440 43b84e44095267b8503fa29d853a7833 414 SMART SM00671 219 254 9.0E-8 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07440 43b84e44095267b8503fa29d853a7833 414 SMART SM00671 327 362 9.2E-6 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07440 43b84e44095267b8503fa29d853a7833 414 Pfam PF08238 Sel1 repeat 329 362 5.0E-7 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07440 43b84e44095267b8503fa29d853a7833 414 Pfam PF08238 Sel1 repeat 257 290 1.6E-6 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07440 43b84e44095267b8503fa29d853a7833 414 Pfam PF08238 Sel1 repeat 291 325 0.0081 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07440 43b84e44095267b8503fa29d853a7833 414 Pfam PF08238 Sel1 repeat 123 145 0.0015 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07440 43b84e44095267b8503fa29d853a7833 414 Pfam PF08238 Sel1 repeat 220 254 2.6E-8 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07440 43b84e44095267b8503fa29d853a7833 414 Pfam PF08238 Sel1 repeat 147 182 2.3E-5 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07440 43b84e44095267b8503fa29d853a7833 414 Pfam PF08238 Sel1 repeat 184 218 1.1E-4 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07440 43b84e44095267b8503fa29d853a7833 414 Pfam PF08238 Sel1 repeat 363 398 5.7E-7 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_29185 8b3777f751857ee2233bb188b7d550ce 535 SUPERFAMILY SSF53756 314 510 6.67E-16 T 14-10-2018 TSH58p_29185 8b3777f751857ee2233bb188b7d550ce 535 Gene3D G3DSA:3.40.50.2000 341 496 3.4E-17 T 14-10-2018 TSH58p_29185 8b3777f751857ee2233bb188b7d550ce 535 Pfam PF13692 Glycosyl transferases group 1 372 480 9.6E-10 T 14-10-2018 TSH58p_18300 ba055da1e7a8e6d0787ae0863f9f02b2 1065 Pfam PF00534 Glycosyl transferases group 1 732 878 2.6E-18 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 TSH58p_18300 ba055da1e7a8e6d0787ae0863f9f02b2 1065 Gene3D G3DSA:3.40.50.2000 710 884 2.0E-35 T 14-10-2018 TSH58p_18300 ba055da1e7a8e6d0787ae0863f9f02b2 1065 Gene3D G3DSA:3.40.50.2000 664 894 2.0E-35 T 14-10-2018 TSH58p_18300 ba055da1e7a8e6d0787ae0863f9f02b2 1065 SUPERFAMILY SSF53756 526 898 8.52E-47 T 14-10-2018 TSH58p_18300 ba055da1e7a8e6d0787ae0863f9f02b2 1065 Pfam PF00535 Glycosyl transferase family 2 277 395 8.2E-25 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_18300 ba055da1e7a8e6d0787ae0863f9f02b2 1065 Gene3D G3DSA:3.90.550.10 260 510 2.8E-49 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_18300 ba055da1e7a8e6d0787ae0863f9f02b2 1065 SUPERFAMILY SSF53448 274 488 2.25E-46 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_23920 d8ecef4a5de94dc4207b68f8ccfc7d84 157 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 1 148 29.728 T 14-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 TSH58p_23920 d8ecef4a5de94dc4207b68f8ccfc7d84 157 Pfam PF00588 SpoU rRNA Methylase family 2 138 3.5E-27 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TSH58p_23920 d8ecef4a5de94dc4207b68f8ccfc7d84 157 Gene3D G3DSA:3.40.1280.10 1 151 5.7E-47 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TSH58p_23920 d8ecef4a5de94dc4207b68f8ccfc7d84 157 SUPERFAMILY SSF75217 2 145 7.85E-37 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases TSH58p_23920 d8ecef4a5de94dc4207b68f8ccfc7d84 157 PIRSF PIRSF029256 1 150 2.2E-49 T 14-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 TSH58p_18890 1cb2a7a3d3d0b7d75f864314fe027ece 282 Pfam PF13460 NAD(P)H-binding 7 181 7.2E-26 T 14-10-2018 IPR016040 NAD(P)-binding domain TSH58p_18890 1cb2a7a3d3d0b7d75f864314fe027ece 282 Gene3D G3DSA:3.90.25.10 135 267 2.8E-89 T 14-10-2018 TSH58p_18890 1cb2a7a3d3d0b7d75f864314fe027ece 282 SUPERFAMILY SSF51735 2 246 5.56E-60 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_18890 1cb2a7a3d3d0b7d75f864314fe027ece 282 Gene3D G3DSA:3.40.50.720 4 265 2.8E-89 T 14-10-2018 TSH58p_20835 f9ad9b9eec03f70e702df941e906b37c 130 Pfam PF13467 Ribbon-helix-helix domain 16 82 1.2E-21 T 14-10-2018 IPR027373 Ribbon-helix-helix domain TSH58p_20835 f9ad9b9eec03f70e702df941e906b37c 130 Gene3D G3DSA:1.10.3990.20 8 112 1.5E-26 T 14-10-2018 IPR038268 Ribbon-helix-helix domain superfamily TSH58p_18650 f13befb41aa609f9ca2630cf2c3efe5f 272 SUPERFAMILY SSF49899 3 245 2.26E-19 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily TSH58p_18650 f13befb41aa609f9ca2630cf2c3efe5f 272 Gene3D G3DSA:2.60.120.180 4 249 5.2E-43 T 14-10-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSH58p_18650 f13befb41aa609f9ca2630cf2c3efe5f 272 Pfam PF01670 Glycosyl hydrolase family 12 63 246 6.6E-12 T 14-10-2018 IPR002594 Glycoside hydrolase family 12 GO:0000272|GO:0008810 TSH58p_05575 a884ffe36e096b0c9a203e36c29cb901 276 Pfam PF00793 DAHP synthetase I family 11 263 9.0E-71 T 14-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 TSH58p_05575 a884ffe36e096b0c9a203e36c29cb901 276 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 19 274 1.1E-124 T 14-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 TSH58p_05575 a884ffe36e096b0c9a203e36c29cb901 276 Gene3D G3DSA:3.20.20.70 2 275 1.8E-101 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_05575 a884ffe36e096b0c9a203e36c29cb901 276 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 14 276 53.466 T 14-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 TSH58p_05575 a884ffe36e096b0c9a203e36c29cb901 276 SUPERFAMILY SSF51569 5 275 3.85E-108 T 14-10-2018 TSH58p_23085 4fffb9dc492481a862083a52d7314500 296 SUPERFAMILY SSF53850 93 294 1.21E-47 T 14-10-2018 TSH58p_23085 4fffb9dc492481a862083a52d7314500 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.7E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_23085 4fffb9dc492481a862083a52d7314500 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.7E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_23085 4fffb9dc492481a862083a52d7314500 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.7E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_23085 4fffb9dc492481a862083a52d7314500 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 5.3E-23 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_23085 4fffb9dc492481a862083a52d7314500 296 Gene3D G3DSA:1.10.10.10 1 82 6.4E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_23085 4fffb9dc492481a862083a52d7314500 296 Gene3D G3DSA:3.40.190.290 93 295 9.6E-53 T 14-10-2018 TSH58p_23085 4fffb9dc492481a862083a52d7314500 296 Pfam PF03466 LysR substrate binding domain 90 292 1.5E-48 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_23085 4fffb9dc492481a862083a52d7314500 296 SUPERFAMILY SSF46785 3 113 2.32E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_12480 c7420c2da3e24bf18b9fcd987784a344 916 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 824 20.305 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TSH58p_12480 c7420c2da3e24bf18b9fcd987784a344 916 Gene3D G3DSA:3.40.50.300 404 612 8.0E-89 T 14-10-2018 TSH58p_12480 c7420c2da3e24bf18b9fcd987784a344 916 SUPERFAMILY SSF52540 403 611 2.58E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_12480 c7420c2da3e24bf18b9fcd987784a344 916 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 809 0.0 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TSH58p_12480 c7420c2da3e24bf18b9fcd987784a344 916 SUPERFAMILY SSF52540 7 402 1.69E-83 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_12480 c7420c2da3e24bf18b9fcd987784a344 916 Pfam PF07517 SecA DEAD-like domain 7 388 7.7E-133 T 14-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 TSH58p_12480 c7420c2da3e24bf18b9fcd987784a344 916 Gene3D G3DSA:3.10.450.50 875 915 2.1E-6 T 14-10-2018 TSH58p_12480 c7420c2da3e24bf18b9fcd987784a344 916 SUPERFAMILY SSF81767 227 355 1.96E-43 T 14-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 TSH58p_12480 c7420c2da3e24bf18b9fcd987784a344 916 Pfam PF01043 SecA preprotein cross-linking domain 232 345 3.9E-39 T 14-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 TSH58p_12480 c7420c2da3e24bf18b9fcd987784a344 916 SUPERFAMILY SSF81886 613 904 2.35E-80 T 14-10-2018 IPR036266 SecA, Wing/Scaffold superfamily TSH58p_12480 c7420c2da3e24bf18b9fcd987784a344 916 Pfam PF02810 SEC-C motif 896 914 5.5E-9 T 14-10-2018 IPR004027 SEC-C motif TSH58p_12480 c7420c2da3e24bf18b9fcd987784a344 916 PRINTS PR00906 SecA protein signature 170 190 9.1E-70 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TSH58p_12480 c7420c2da3e24bf18b9fcd987784a344 916 PRINTS PR00906 SecA protein signature 326 348 9.1E-70 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TSH58p_12480 c7420c2da3e24bf18b9fcd987784a344 916 PRINTS PR00906 SecA protein signature 63 87 9.1E-70 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TSH58p_12480 c7420c2da3e24bf18b9fcd987784a344 916 PRINTS PR00906 SecA protein signature 363 380 9.1E-70 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TSH58p_12480 c7420c2da3e24bf18b9fcd987784a344 916 PRINTS PR00906 SecA protein signature 400 413 9.1E-70 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TSH58p_12480 c7420c2da3e24bf18b9fcd987784a344 916 PRINTS PR00906 SecA protein signature 101 115 9.1E-70 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TSH58p_12480 c7420c2da3e24bf18b9fcd987784a344 916 PRINTS PR00906 SecA protein signature 117 127 9.1E-70 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TSH58p_12480 c7420c2da3e24bf18b9fcd987784a344 916 Gene3D G3DSA:3.40.50.300 22 402 4.4E-179 T 14-10-2018 TSH58p_12480 c7420c2da3e24bf18b9fcd987784a344 916 SMART SM00958 228 345 1.3E-73 T 14-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 TSH58p_12480 c7420c2da3e24bf18b9fcd987784a344 916 SMART SM00957 6 389 1.3E-301 T 14-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 TSH58p_12480 c7420c2da3e24bf18b9fcd987784a344 916 Gene3D G3DSA:3.90.1440.10 229 355 4.4E-179 T 14-10-2018 TSH58p_12480 c7420c2da3e24bf18b9fcd987784a344 916 Gene3D G3DSA:1.10.3060.10 614 825 9.5E-74 T 14-10-2018 TSH58p_12480 c7420c2da3e24bf18b9fcd987784a344 916 Pfam PF07516 SecA Wing and Scaffold domain 611 821 1.3E-67 T 14-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 TSH58p_12480 c7420c2da3e24bf18b9fcd987784a344 916 ProSitePatterns PS01312 SecA family signature. 487 502 - T 14-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 TSH58p_28445 a56728f9784392e347333541ca8e899b 589 Pfam PF00512 His Kinase A (phospho-acceptor) domain 356 424 1.8E-18 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_28445 a56728f9784392e347333541ca8e899b 589 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 471 585 1.2E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_28445 a56728f9784392e347333541ca8e899b 589 Gene3D G3DSA:3.30.450.320 38 159 3.5E-20 T 14-10-2018 TSH58p_28445 a56728f9784392e347333541ca8e899b 589 SUPERFAMILY SSF55874 413 584 1.57E-43 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_28445 a56728f9784392e347333541ca8e899b 589 SMART SM00065 167 341 1.6E-8 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_28445 a56728f9784392e347333541ca8e899b 589 SMART SM00388 356 424 7.7E-22 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_28445 a56728f9784392e347333541ca8e899b 589 SUPERFAMILY SSF55781 162 335 8.51E-31 T 14-10-2018 TSH58p_28445 a56728f9784392e347333541ca8e899b 589 Pfam PF01590 GAF domain 168 327 9.1E-13 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_28445 a56728f9784392e347333541ca8e899b 589 SUPERFAMILY SSF47384 346 425 5.89E-22 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_28445 a56728f9784392e347333541ca8e899b 589 Gene3D G3DSA:1.10.287.130 343 424 3.6E-25 T 14-10-2018 TSH58p_28445 a56728f9784392e347333541ca8e899b 589 Pfam PF08446 PAS fold 40 137 3.7E-11 T 14-10-2018 IPR013654 PAS fold-2 GO:0006355 TSH58p_28445 a56728f9784392e347333541ca8e899b 589 PRINTS PR00344 Bacterial sensor protein C-terminal signature 546 564 2.7E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_28445 a56728f9784392e347333541ca8e899b 589 PRINTS PR00344 Bacterial sensor protein C-terminal signature 511 525 2.7E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_28445 a56728f9784392e347333541ca8e899b 589 PRINTS PR00344 Bacterial sensor protein C-terminal signature 570 583 2.7E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_28445 a56728f9784392e347333541ca8e899b 589 SMART SM00387 470 586 2.4E-37 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_28445 a56728f9784392e347333541ca8e899b 589 Gene3D G3DSA:3.30.450.40 160 342 4.4E-32 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_28445 a56728f9784392e347333541ca8e899b 589 Gene3D G3DSA:3.30.565.10 425 587 2.6E-40 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_28445 a56728f9784392e347333541ca8e899b 589 SUPERFAMILY SSF55785 40 138 2.62E-15 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_31075 3e0f6530aab9b1eb70f126e4301bb2d9 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 215 0.0077 T 14-10-2018 TSH58p_31075 3e0f6530aab9b1eb70f126e4301bb2d9 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 252 1.9E-57 T 14-10-2018 TSH58p_31075 3e0f6530aab9b1eb70f126e4301bb2d9 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_31075 3e0f6530aab9b1eb70f126e4301bb2d9 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 3.2E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_31075 3e0f6530aab9b1eb70f126e4301bb2d9 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 3.2E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_31075 3e0f6530aab9b1eb70f126e4301bb2d9 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 3.2E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_31075 3e0f6530aab9b1eb70f126e4301bb2d9 253 SUPERFAMILY SSF51735 10 252 9.01E-74 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_31075 3e0f6530aab9b1eb70f126e4301bb2d9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 3.9E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_31075 3e0f6530aab9b1eb70f126e4301bb2d9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 3.9E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_31075 3e0f6530aab9b1eb70f126e4301bb2d9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 3.9E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_31075 3e0f6530aab9b1eb70f126e4301bb2d9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 3.9E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_31075 3e0f6530aab9b1eb70f126e4301bb2d9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 3.9E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_31075 3e0f6530aab9b1eb70f126e4301bb2d9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.9E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_31075 3e0f6530aab9b1eb70f126e4301bb2d9 253 Gene3D G3DSA:3.40.50.720 3 253 1.5E-78 T 14-10-2018 TSH58p_07280 e53adedc8c8090060ce9a34515703935 565 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 13 181 2.2E-37 T 14-10-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal TSH58p_07280 e53adedc8c8090060ce9a34515703935 565 SUPERFAMILY SSF56747 9 189 1.44E-26 T 14-10-2018 TSH58p_07280 e53adedc8c8090060ce9a34515703935 565 SMART SM00943 13 182 2.5E-39 T 14-10-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal TSH58p_27495 9161d9d69622e6acef64f6e5aebfd34b 214 Gene3D G3DSA:1.10.287.130 3 77 3.1E-26 T 14-10-2018 TSH58p_27495 9161d9d69622e6acef64f6e5aebfd34b 214 Pfam PF10090 Histidine phosphotransferase C-terminal domain 80 204 3.2E-28 T 14-10-2018 IPR018762 Histidine phosphotransferase ChpT, C-terminal TSH58p_27495 9161d9d69622e6acef64f6e5aebfd34b 214 Gene3D G3DSA:3.30.565.10 78 213 4.5E-32 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_19395 1a497a36fe47a404bf4d1d82aad20d8e 318 Gene3D G3DSA:3.40.50.620 2 192 7.9E-55 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_19395 1a497a36fe47a404bf4d1d82aad20d8e 318 SUPERFAMILY SSF52402 2 193 3.85E-54 T 14-10-2018 TSH58p_19395 1a497a36fe47a404bf4d1d82aad20d8e 318 Pfam PF01012 Electron transfer flavoprotein domain 4 176 1.7E-41 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 TSH58p_19395 1a497a36fe47a404bf4d1d82aad20d8e 318 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 199 281 5.9E-38 T 14-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 TSH58p_19395 1a497a36fe47a404bf4d1d82aad20d8e 318 Gene3D G3DSA:3.40.50.1220 193 318 4.0E-59 T 14-10-2018 TSH58p_19395 1a497a36fe47a404bf4d1d82aad20d8e 318 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 262 288 - T 14-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 TSH58p_19395 1a497a36fe47a404bf4d1d82aad20d8e 318 SUPERFAMILY SSF52467 196 316 2.47E-49 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TSH58p_19395 1a497a36fe47a404bf4d1d82aad20d8e 318 PIRSF PIRSF000089 1 318 1.3E-110 T 14-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 TSH58p_19395 1a497a36fe47a404bf4d1d82aad20d8e 318 SMART SM00893 3 191 1.1E-51 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 TSH58p_30620 8be44e4babf517b0807963da31164de9 431 PIRSF PIRSF001434 1 431 1.5E-119 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TSH58p_30620 8be44e4babf517b0807963da31164de9 431 Gene3D G3DSA:3.40.640.10 7 293 5.1E-89 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_30620 8be44e4babf517b0807963da31164de9 431 SUPERFAMILY SSF53383 7 429 9.39E-112 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_30620 8be44e4babf517b0807963da31164de9 431 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 7 429 1.6E-178 T 14-10-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 TSH58p_30620 8be44e4babf517b0807963da31164de9 431 Gene3D G3DSA:3.90.1150.10 297 431 1.6E-47 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_30620 8be44e4babf517b0807963da31164de9 431 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 9 428 2.1E-123 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TSH58p_11790 660bf30c04690c1e065a29308d2bf7b8 232 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 36 222 7.5E-19 T 14-10-2018 TSH58p_11790 660bf30c04690c1e065a29308d2bf7b8 232 Gene3D G3DSA:3.40.50.1000 36 230 1.7E-33 T 14-10-2018 IPR023214 HAD superfamily TSH58p_11790 660bf30c04690c1e065a29308d2bf7b8 232 SUPERFAMILY SSF56784 36 225 5.97E-20 T 14-10-2018 IPR036412 HAD-like superfamily TSH58p_11790 660bf30c04690c1e065a29308d2bf7b8 232 Pfam PF12710 haloacid dehalogenase-like hydrolase 37 220 6.8E-29 T 14-10-2018 TSH58p_11790 660bf30c04690c1e065a29308d2bf7b8 232 Gene3D G3DSA:1.20.1440.100 48 122 1.7E-33 T 14-10-2018 TSH58p_11790 660bf30c04690c1e065a29308d2bf7b8 232 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 37 230 2.8E-32 T 14-10-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like TSH58p_10855 a98b3adf8f1b19c677a045bbc977dbc3 418 Gene3D G3DSA:3.40.50.2000 212 364 2.2E-13 T 14-10-2018 TSH58p_10855 a98b3adf8f1b19c677a045bbc977dbc3 418 SUPERFAMILY SSF53756 9 361 4.13E-15 T 14-10-2018 TSH58p_11925 3a823ff088acb0fffbca67da2a00f82b 528 Gene3D G3DSA:3.40.50.2300 23 171 4.2E-14 T 14-10-2018 TSH58p_11925 3a823ff088acb0fffbca67da2a00f82b 528 Pfam PF13487 HD domain 405 473 2.2E-17 T 14-10-2018 TSH58p_11925 3a823ff088acb0fffbca67da2a00f82b 528 SUPERFAMILY SSF109604 374 520 4.0E-28 T 14-10-2018 TSH58p_11925 3a823ff088acb0fffbca67da2a00f82b 528 Pfam PF11849 Domain of unknown function (DUF3369) 154 322 3.5E-58 T 14-10-2018 IPR021800 Domain of unknown function DUF3369 TSH58p_11925 3a823ff088acb0fffbca67da2a00f82b 528 SMART SM00471 325 492 2.2E-4 T 14-10-2018 IPR003607 HD/PDEase domain TSH58p_11925 3a823ff088acb0fffbca67da2a00f82b 528 Pfam PF00072 Response regulator receiver domain 34 143 2.4E-8 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_11925 3a823ff088acb0fffbca67da2a00f82b 528 SUPERFAMILY SSF52172 29 167 2.28E-12 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_11925 3a823ff088acb0fffbca67da2a00f82b 528 Gene3D G3DSA:1.10.3210.10 319 527 7.5E-59 T 14-10-2018 TSH58p_03990 1db56a237361d5287b63e1106224a0a5 275 SUPERFAMILY SSF55920 12 260 2.36E-85 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like TSH58p_03990 1db56a237361d5287b63e1106224a0a5 275 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 10 256 1.2E-89 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSH58p_03990 1db56a237361d5287b63e1106224a0a5 275 Gene3D G3DSA:3.90.230.10 5 266 1.1E-100 T 14-10-2018 TSH58p_03990 1db56a237361d5287b63e1106224a0a5 275 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 174 192 - T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSH58p_03990 1db56a237361d5287b63e1106224a0a5 275 PRINTS PR00599 Methionine aminopeptidase-1 signature 97 113 1.3E-20 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSH58p_03990 1db56a237361d5287b63e1106224a0a5 275 PRINTS PR00599 Methionine aminopeptidase-1 signature 168 180 1.3E-20 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSH58p_03990 1db56a237361d5287b63e1106224a0a5 275 PRINTS PR00599 Methionine aminopeptidase-1 signature 199 211 1.3E-20 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSH58p_03990 1db56a237361d5287b63e1106224a0a5 275 PRINTS PR00599 Methionine aminopeptidase-1 signature 74 87 1.3E-20 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSH58p_03990 1db56a237361d5287b63e1106224a0a5 275 Pfam PF00557 Metallopeptidase family M24 18 248 2.9E-50 T 14-10-2018 IPR000994 Peptidase M24 TSH58p_03990 1db56a237361d5287b63e1106224a0a5 275 Hamap MF_01974 Methionine aminopeptidase [map]. 9 257 39.273 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSH58p_07765 e41538117a689c50563ac17ddcc176bf 663 Gene3D G3DSA:1.10.8.500 209 258 2.4E-14 T 14-10-2018 TSH58p_07765 e41538117a689c50563ac17ddcc176bf 663 SMART SM00283 298 552 1.8E-38 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_07765 e41538117a689c50563ac17ddcc176bf 663 SUPERFAMILY SSF141371 556 635 5.3E-5 T 14-10-2018 TSH58p_07765 e41538117a689c50563ac17ddcc176bf 663 SMART SM00304 208 261 1.8E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_07765 e41538117a689c50563ac17ddcc176bf 663 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 473 502 2.9E-22 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_07765 e41538117a689c50563ac17ddcc176bf 663 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 396 423 2.9E-22 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_07765 e41538117a689c50563ac17ddcc176bf 663 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 425 454 2.9E-22 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_07765 e41538117a689c50563ac17ddcc176bf 663 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 3 28 2.9E-22 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_07765 e41538117a689c50563ac17ddcc176bf 663 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 376 518 1.0E-31 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_07765 e41538117a689c50563ac17ddcc176bf 663 Pfam PF02203 Tar ligand binding domain homologue 2 168 3.3E-14 T 14-10-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 TSH58p_07765 e41538117a689c50563ac17ddcc176bf 663 Gene3D G3DSA:1.10.287.950 259 538 3.1E-47 T 14-10-2018 TSH58p_07765 e41538117a689c50563ac17ddcc176bf 663 SUPERFAMILY SSF58104 237 546 3.4E-55 T 14-10-2018 TSH58p_07765 e41538117a689c50563ac17ddcc176bf 663 Pfam PF00672 HAMP domain 209 252 1.2E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_07845 38b727d6d91cb795cf1dcd548a58d480 127 SUPERFAMILY SSF51182 25 111 1.08E-17 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_07845 38b727d6d91cb795cf1dcd548a58d480 127 Pfam PF07883 Cupin domain 54 110 6.7E-11 T 14-10-2018 IPR013096 Cupin 2, conserved barrel TSH58p_07845 38b727d6d91cb795cf1dcd548a58d480 127 Gene3D G3DSA:2.60.120.10 19 114 3.0E-35 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_01245 ea8bd140a86815bc10952ccf9372d17d 276 Pfam PF08770 Sulphur oxidation protein SoxZ 180 268 4.5E-26 T 14-10-2018 IPR014880 Sulphur oxidation protein SoxZ TSH58p_01245 ea8bd140a86815bc10952ccf9372d17d 276 Pfam PF13501 Sulfur oxidation protein SoxY 46 152 5.0E-28 T 14-10-2018 IPR032711 Ig-like SoxY domain TSH58p_01245 ea8bd140a86815bc10952ccf9372d17d 276 SUPERFAMILY SSF81296 167 270 5.74E-28 T 14-10-2018 IPR014756 Immunoglobulin E-set TSH58p_01245 ea8bd140a86815bc10952ccf9372d17d 276 TIGRFAM TIGR04557 fuse_rel_SoxYZ: quinoprotein dehydrogenase-associated SoxYZ-like carrier 39 265 7.6E-74 T 14-10-2018 IPR030831 Quinoprotein dehydrogenase-associated SoxYZ-like carrier TSH58p_01245 ea8bd140a86815bc10952ccf9372d17d 276 Gene3D G3DSA:2.60.40.2470 22 152 1.1E-28 T 14-10-2018 IPR038162 Ig-like SoxY domain superfamily TSH58p_01245 ea8bd140a86815bc10952ccf9372d17d 276 Gene3D G3DSA:2.60.40.10 165 272 1.1E-22 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_08020 5c1b8d89c485ef1ce307aca31d1924f6 464 Gene3D G3DSA:3.40.710.10 59 339 2.0E-79 T 14-10-2018 TSH58p_08020 5c1b8d89c485ef1ce307aca31d1924f6 464 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 183 196 1.7E-12 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 TSH58p_08020 5c1b8d89c485ef1ce307aca31d1924f6 464 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 156 173 1.7E-12 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 TSH58p_08020 5c1b8d89c485ef1ce307aca31d1924f6 464 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 103 114 1.7E-12 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 TSH58p_08020 5c1b8d89c485ef1ce307aca31d1924f6 464 Pfam PF05036 Sporulation related domain 380 457 7.0E-8 T 14-10-2018 IPR007730 Sporulation-like domain GO:0042834 TSH58p_08020 5c1b8d89c485ef1ce307aca31d1924f6 464 SUPERFAMILY SSF56601 59 314 1.56E-73 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TSH58p_08020 5c1b8d89c485ef1ce307aca31d1924f6 464 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 75 296 2.4E-56 T 14-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 TSH58p_22890 c97ee4e21906474d659652ba2cbb5411 468 Gene3D G3DSA:3.30.499.20 9 288 9.5E-90 T 14-10-2018 TSH58p_22890 c97ee4e21906474d659652ba2cbb5411 468 Gene3D G3DSA:3.30.499.10 328 468 3.9E-47 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 TSH58p_22890 c97ee4e21906474d659652ba2cbb5411 468 Pfam PF00330 Aconitase family (aconitate hydratase) 10 457 3.1E-139 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_22890 c97ee4e21906474d659652ba2cbb5411 468 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 4 466 52.32 T 14-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 TSH58p_22890 c97ee4e21906474d659652ba2cbb5411 468 PRINTS PR00415 Aconitase family signature 399 412 4.4E-44 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_22890 c97ee4e21906474d659652ba2cbb5411 468 PRINTS PR00415 Aconitase family signature 110 118 4.4E-44 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_22890 c97ee4e21906474d659652ba2cbb5411 468 PRINTS PR00415 Aconitase family signature 197 210 4.4E-44 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_22890 c97ee4e21906474d659652ba2cbb5411 468 PRINTS PR00415 Aconitase family signature 211 224 4.4E-44 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_22890 c97ee4e21906474d659652ba2cbb5411 468 PRINTS PR00415 Aconitase family signature 121 134 4.4E-44 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_22890 c97ee4e21906474d659652ba2cbb5411 468 PRINTS PR00415 Aconitase family signature 288 302 4.4E-44 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_22890 c97ee4e21906474d659652ba2cbb5411 468 PRINTS PR00415 Aconitase family signature 345 356 4.4E-44 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_22890 c97ee4e21906474d659652ba2cbb5411 468 PRINTS PR00415 Aconitase family signature 135 150 4.4E-44 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_22890 c97ee4e21906474d659652ba2cbb5411 468 ProSitePatterns PS00450 Aconitase family signature 1. 341 357 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 TSH58p_22890 c97ee4e21906474d659652ba2cbb5411 468 ProSitePatterns PS01244 Aconitase family signature 2. 399 412 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 TSH58p_22890 c97ee4e21906474d659652ba2cbb5411 468 SUPERFAMILY SSF53732 4 465 6.41E-153 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 TSH58p_22890 c97ee4e21906474d659652ba2cbb5411 468 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 5 465 2.9E-201 T 14-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 TSH58p_16625 6045fbd7fac5d3e270a419035e36d8fb 628 SMART SM00044 380 594 2.6E-14 T 14-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 TSH58p_16625 6045fbd7fac5d3e270a419035e36d8fb 628 Pfam PF05226 CHASE2 domain 43 314 2.7E-29 T 14-10-2018 IPR007890 CHASE2 TSH58p_16625 6045fbd7fac5d3e270a419035e36d8fb 628 Gene3D G3DSA:3.30.70.1230 413 622 2.7E-58 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_16625 6045fbd7fac5d3e270a419035e36d8fb 628 SMART SM01080 48 319 2.6E-28 T 14-10-2018 IPR007890 CHASE2 TSH58p_16625 6045fbd7fac5d3e270a419035e36d8fb 628 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 421 610 2.7E-29 T 14-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 TSH58p_16625 6045fbd7fac5d3e270a419035e36d8fb 628 SUPERFAMILY SSF55073 414 614 1.57E-52 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_24810 6dfb75a1eb183789c439b778c2be15f7 98 SUPERFAMILY SSF46785 22 91 7.21E-7 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_24810 6dfb75a1eb183789c439b778c2be15f7 98 Pfam PF13545 Crp-like helix-turn-helix domain 42 77 3.0E-6 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_24810 6dfb75a1eb183789c439b778c2be15f7 98 Gene3D G3DSA:1.10.10.10 2 95 1.9E-7 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_08585 5f97a6279b24940d387c88d93888ec46 413 Pfam PF01479 S4 domain 27 73 5.4E-11 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_08585 5f97a6279b24940d387c88d93888ec46 413 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 125 139 - T 14-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 TSH58p_08585 5f97a6279b24940d387c88d93888ec46 413 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 92 245 1.5E-36 T 14-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 TSH58p_08585 5f97a6279b24940d387c88d93888ec46 413 SMART SM00363 27 85 4.0E-12 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_08585 5f97a6279b24940d387c88d93888ec46 413 SUPERFAMILY SSF55120 85 242 7.91E-35 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSH58p_08585 5f97a6279b24940d387c88d93888ec46 413 Pfam PF00849 RNA pseudouridylate synthase 91 220 9.5E-12 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSH58p_08585 5f97a6279b24940d387c88d93888ec46 413 Gene3D G3DSA:3.10.290.10 23 81 6.0E-19 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TSH58p_08585 5f97a6279b24940d387c88d93888ec46 413 Gene3D G3DSA:3.30.70.580 91 244 6.9E-46 T 14-10-2018 TSH58p_08585 5f97a6279b24940d387c88d93888ec46 413 Gene3D G3DSA:3.30.70.1560 149 239 6.9E-46 T 14-10-2018 TSH58p_08585 5f97a6279b24940d387c88d93888ec46 413 SUPERFAMILY SSF55174 24 81 2.35E-14 T 14-10-2018 TSH58p_31450 1930914055906ced25583832451974f1 225 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 1.6E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_31450 1930914055906ced25583832451974f1 225 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 1.6E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_31450 1930914055906ced25583832451974f1 225 SMART SM00345 24 82 4.9E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_31450 1930914055906ced25583832451974f1 225 SUPERFAMILY SSF48008 89 219 3.66E-21 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_31450 1930914055906ced25583832451974f1 225 Gene3D G3DSA:1.20.120.530 84 223 1.4E-26 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_31450 1930914055906ced25583832451974f1 225 Gene3D G3DSA:1.10.10.10 3 83 1.4E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_31450 1930914055906ced25583832451974f1 225 Pfam PF07729 FCD domain 93 212 2.5E-21 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_31450 1930914055906ced25583832451974f1 225 SUPERFAMILY SSF46785 16 86 2.54E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_31450 1930914055906ced25583832451974f1 225 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 74 2.7E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_31450 1930914055906ced25583832451974f1 225 SMART SM00895 92 213 1.2E-16 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_27505 7814acb9621688b1560d45bcbd188048 166 Gene3D G3DSA:2.30.30.40 27 152 3.8E-33 T 14-10-2018 TSH58p_27505 7814acb9621688b1560d45bcbd188048 166 Gene3D G3DSA:2.40.50.180 44 153 3.8E-33 T 14-10-2018 TSH58p_27505 7814acb9621688b1560d45bcbd188048 166 SMART SM00260 21 158 2.2E-33 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TSH58p_27505 7814acb9621688b1560d45bcbd188048 166 SUPERFAMILY SSF50341 23 160 8.11E-32 T 14-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 TSH58p_27505 7814acb9621688b1560d45bcbd188048 166 Pfam PF01584 CheW-like domain 26 159 3.2E-30 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TSH58p_09815 8d2ba0688d4326d6f9881d0204ee6d7d 188 Gene3D G3DSA:3.90.960.10 10 180 2.5E-51 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 TSH58p_09815 8d2ba0688d4326d6f9881d0204ee6d7d 188 SUPERFAMILY SSF55826 17 177 1.31E-45 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 TSH58p_09815 8d2ba0688d4326d6f9881d0204ee6d7d 188 Pfam PF04073 Aminoacyl-tRNA editing domain 38 163 5.5E-27 T 14-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 TSH58p_30305 658f2177b197951091d24878de28342d 302 Pfam PF01136 Peptidase family U32 98 291 2.0E-14 T 14-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 TSH58p_05170 030b931f6361f0df671b29d754165190 229 SUPERFAMILY SSF46785 12 108 2.12E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_05170 030b931f6361f0df671b29d754165190 229 Pfam PF07729 FCD domain 92 213 3.1E-24 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_05170 030b931f6361f0df671b29d754165190 229 Gene3D G3DSA:1.20.120.530 86 226 9.1E-27 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_05170 030b931f6361f0df671b29d754165190 229 SMART SM00895 92 216 6.6E-16 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_05170 030b931f6361f0df671b29d754165190 229 SMART SM00345 21 82 3.0E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_05170 030b931f6361f0df671b29d754165190 229 Gene3D G3DSA:1.10.10.10 13 83 9.6E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_05170 030b931f6361f0df671b29d754165190 229 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 82 3.9E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_05170 030b931f6361f0df671b29d754165190 229 SUPERFAMILY SSF48008 89 223 1.65E-23 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_05170 030b931f6361f0df671b29d754165190 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 6.1E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_05170 030b931f6361f0df671b29d754165190 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 6.1E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_05570 e663192c68c576934f934e09d6cf8285 259 Pfam PF06707 Protein of unknown function (DUF1194) 43 240 5.1E-54 T 14-10-2018 IPR010607 Protein of unknown function DUF1194 TSH58p_05570 e663192c68c576934f934e09d6cf8285 259 Gene3D G3DSA:3.40.50.410 42 243 4.4E-12 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TSH58p_05570 e663192c68c576934f934e09d6cf8285 259 SUPERFAMILY SSF53300 43 239 2.52E-20 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TSH58p_08220 aeb83534114f59ae25a7bdbfae9a42db 343 SUPERFAMILY SSF52518 4 201 1.87E-64 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_08220 aeb83534114f59ae25a7bdbfae9a42db 343 Pfam PF02780 Transketolase, C-terminal domain 203 325 2.8E-39 T 14-10-2018 IPR033248 Transketolase, C-terminal domain TSH58p_08220 aeb83534114f59ae25a7bdbfae9a42db 343 SUPERFAMILY SSF52922 198 333 6.28E-39 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSH58p_08220 aeb83534114f59ae25a7bdbfae9a42db 343 Gene3D G3DSA:3.40.50.970 1 201 1.5E-81 T 14-10-2018 TSH58p_08220 aeb83534114f59ae25a7bdbfae9a42db 343 Pfam PF02779 Transketolase, pyrimidine binding domain 4 189 4.9E-55 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSH58p_08220 aeb83534114f59ae25a7bdbfae9a42db 343 Gene3D G3DSA:3.40.50.920 202 334 2.1E-43 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSH58p_08220 aeb83534114f59ae25a7bdbfae9a42db 343 SMART SM00861 5 189 2.6E-63 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSH58p_25650 b1e960e4b7ce4a6dc45135720bfeba64 395 Pfam PF06181 Urate oxidase N-terminal 4 294 3.0E-136 T 14-10-2018 IPR010389 Urate oxidase N-terminal TSH58p_25650 b1e960e4b7ce4a6dc45135720bfeba64 395 SUPERFAMILY SSF46626 298 393 3.95E-6 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_30905 326b6c05739c94ebddcd951eba7b65b7 194 SUPERFAMILY SSF55469 6 191 5.5E-40 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TSH58p_30905 326b6c05739c94ebddcd951eba7b65b7 194 Gene3D G3DSA:3.40.109.10 3 193 5.2E-43 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TSH58p_30905 326b6c05739c94ebddcd951eba7b65b7 194 Pfam PF00881 Nitroreductase family 19 158 1.7E-11 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TSH58p_28070 edb90bd3d3a86440114c4e9c5c4becd0 159 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 4 148 1.9E-42 T 14-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TSH58p_28070 edb90bd3d3a86440114c4e9c5c4becd0 159 Pfam PF01750 Hydrogenase maturation protease 20 147 1.1E-26 T 14-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TSH58p_28070 edb90bd3d3a86440114c4e9c5c4becd0 159 PRINTS PR00446 Hydrogen uptake protein signature 56 66 3.4E-22 T 14-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TSH58p_28070 edb90bd3d3a86440114c4e9c5c4becd0 159 PRINTS PR00446 Hydrogen uptake protein signature 3 15 3.4E-22 T 14-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TSH58p_28070 edb90bd3d3a86440114c4e9c5c4becd0 159 PRINTS PR00446 Hydrogen uptake protein signature 15 26 3.4E-22 T 14-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TSH58p_28070 edb90bd3d3a86440114c4e9c5c4becd0 159 PRINTS PR00446 Hydrogen uptake protein signature 35 52 3.4E-22 T 14-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TSH58p_28070 edb90bd3d3a86440114c4e9c5c4becd0 159 PRINTS PR00446 Hydrogen uptake protein signature 67 83 3.4E-22 T 14-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TSH58p_28070 edb90bd3d3a86440114c4e9c5c4becd0 159 Gene3D G3DSA:3.40.50.1450 1 159 1.1E-41 T 14-10-2018 IPR023430 Peptidase HybD-like domain superfamily TSH58p_28070 edb90bd3d3a86440114c4e9c5c4becd0 159 SUPERFAMILY SSF53163 1 157 1.83E-42 T 14-10-2018 IPR023430 Peptidase HybD-like domain superfamily TSH58p_32190 7a105497ca93ef913c8ad80988da6829 465 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 71 2.9E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_32190 7a105497ca93ef913c8ad80988da6829 465 SUPERFAMILY SSF46785 5 74 2.2E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_32190 7a105497ca93ef913c8ad80988da6829 465 Gene3D G3DSA:3.40.640.10 142 359 1.3E-80 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_32190 7a105497ca93ef913c8ad80988da6829 465 Pfam PF00155 Aminotransferase class I and II 124 455 1.2E-43 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSH58p_32190 7a105497ca93ef913c8ad80988da6829 465 Gene3D G3DSA:1.10.10.10 8 105 3.7E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_32190 7a105497ca93ef913c8ad80988da6829 465 Gene3D G3DSA:3.90.1150.10 108 458 1.3E-80 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_32190 7a105497ca93ef913c8ad80988da6829 465 SMART SM00345 12 71 3.0E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_32190 7a105497ca93ef913c8ad80988da6829 465 SUPERFAMILY SSF53383 65 458 6.38E-84 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_27220 dd810bbecd75cf82fad65653474e603d 217 Pfam PF01865 Protein of unknown function DUF47 5 215 2.9E-29 T 14-10-2018 IPR018445 Putative phosphate transport regulator TSH58p_27220 dd810bbecd75cf82fad65653474e603d 217 Gene3D G3DSA:1.20.58.220 15 216 4.2E-46 T 14-10-2018 IPR038078 PhoU-like domain superfamily TSH58p_16425 467e28bf77161faae5b9badc73a668d5 591 Gene3D G3DSA:3.40.50.2300 27 176 4.9E-12 T 14-10-2018 TSH58p_16425 467e28bf77161faae5b9badc73a668d5 591 Gene3D G3DSA:1.10.287.130 355 435 1.5E-14 T 14-10-2018 TSH58p_16425 467e28bf77161faae5b9badc73a668d5 591 Pfam PF00512 His Kinase A (phospho-acceptor) domain 371 437 3.7E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_16425 467e28bf77161faae5b9badc73a668d5 591 SUPERFAMILY SSF52172 34 182 2.85E-12 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_16425 467e28bf77161faae5b9badc73a668d5 591 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 486 590 9.6E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_16425 467e28bf77161faae5b9badc73a668d5 591 SUPERFAMILY SSF47384 357 438 8.83E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_16425 467e28bf77161faae5b9badc73a668d5 591 Pfam PF11849 Domain of unknown function (DUF3369) 157 325 5.9E-43 T 14-10-2018 IPR021800 Domain of unknown function DUF3369 TSH58p_16425 467e28bf77161faae5b9badc73a668d5 591 SUPERFAMILY SSF55874 429 589 5.37E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_16425 467e28bf77161faae5b9badc73a668d5 591 PRINTS PR00344 Bacterial sensor protein C-terminal signature 575 588 5.3E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_16425 467e28bf77161faae5b9badc73a668d5 591 PRINTS PR00344 Bacterial sensor protein C-terminal signature 551 569 5.3E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_16425 467e28bf77161faae5b9badc73a668d5 591 PRINTS PR00344 Bacterial sensor protein C-terminal signature 518 532 5.3E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_16425 467e28bf77161faae5b9badc73a668d5 591 Gene3D G3DSA:3.30.565.10 436 590 4.3E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_16425 467e28bf77161faae5b9badc73a668d5 591 Pfam PF00072 Response regulator receiver domain 37 146 3.4E-6 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_16425 467e28bf77161faae5b9badc73a668d5 591 SMART SM00387 481 591 2.6E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_16425 467e28bf77161faae5b9badc73a668d5 591 SMART SM00388 370 437 8.6E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_26725 f5ecc7cc227c1591f0023db2158c02d6 95 Pfam PF11804 Protein of unknown function (DUF3325) 4 92 1.1E-18 T 14-10-2018 IPR021762 Protein of unknown function DUF3325 TSH58p_30300 5c0b4da727cec0d9efb5f8b16ffcacb3 332 Pfam PF01136 Peptidase family U32 79 308 1.8E-60 T 14-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 TSH58p_30300 5c0b4da727cec0d9efb5f8b16ffcacb3 332 SUPERFAMILY SSF51391 11 141 6.02E-5 T 14-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSH58p_28655 ab77fe4824f7d1be491f1415dafad8b0 480 Gene3D G3DSA:1.20.5.320 447 479 2.3E-17 T 14-10-2018 TSH58p_28655 ab77fe4824f7d1be491f1415dafad8b0 480 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 192 477 2.3E-114 T 14-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TSH58p_28655 ab77fe4824f7d1be491f1415dafad8b0 480 SUPERFAMILY SSF51735 19 182 5.92E-44 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_28655 ab77fe4824f7d1be491f1415dafad8b0 480 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 19 42 2.8E-72 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TSH58p_28655 ab77fe4824f7d1be491f1415dafad8b0 480 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 132 157 2.8E-72 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TSH58p_28655 ab77fe4824f7d1be491f1415dafad8b0 480 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 79 108 2.8E-72 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TSH58p_28655 ab77fe4824f7d1be491f1415dafad8b0 480 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 263 290 2.8E-72 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TSH58p_28655 ab77fe4824f7d1be491f1415dafad8b0 480 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 181 209 2.8E-72 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TSH58p_28655 ab77fe4824f7d1be491f1415dafad8b0 480 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 367 389 2.8E-72 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TSH58p_28655 ab77fe4824f7d1be491f1415dafad8b0 480 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 267 279 - T 14-10-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TSH58p_28655 ab77fe4824f7d1be491f1415dafad8b0 480 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 20 175 2.3E-43 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 TSH58p_28655 ab77fe4824f7d1be491f1415dafad8b0 480 Gene3D G3DSA:1.10.1040.10 194 445 1.3E-94 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSH58p_28655 ab77fe4824f7d1be491f1415dafad8b0 480 Gene3D G3DSA:3.40.50.720 14 193 3.9E-50 T 14-10-2018 TSH58p_28655 ab77fe4824f7d1be491f1415dafad8b0 480 SUPERFAMILY SSF48179 190 477 5.65E-112 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_28655 ab77fe4824f7d1be491f1415dafad8b0 480 PIRSF PIRSF000109 13 480 1.5E-175 T 14-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TSH58p_28655 ab77fe4824f7d1be491f1415dafad8b0 480 SMART SM01350 192 478 8.8E-174 T 14-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TSH58p_28655 ab77fe4824f7d1be491f1415dafad8b0 480 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 20 478 7.6E-172 T 14-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TSH58p_06160 e0857e71f3840387204013432c3ee9d8 231 Gene3D G3DSA:1.10.150.240 27 92 6.7E-55 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 TSH58p_06160 e0857e71f3840387204013432c3ee9d8 231 SUPERFAMILY SSF56784 10 225 1.32E-55 T 14-10-2018 IPR036412 HAD-like superfamily TSH58p_06160 e0857e71f3840387204013432c3ee9d8 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 16 196 2.8E-32 T 14-10-2018 TSH58p_06160 e0857e71f3840387204013432c3ee9d8 231 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 99 189 1.7E-10 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_06160 e0857e71f3840387204013432c3ee9d8 231 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 88 196 7.6E-10 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_06160 e0857e71f3840387204013432c3ee9d8 231 Gene3D G3DSA:3.40.50.1000 16 215 6.7E-55 T 14-10-2018 IPR023214 HAD superfamily TSH58p_29045 1bac0bd764b724cddaf1cb77e42d51be 254 Gene3D G3DSA:3.60.21.10 20 251 2.9E-59 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like TSH58p_29045 1bac0bd764b724cddaf1cb77e42d51be 254 Pfam PF00149 Calcineurin-like phosphoesterase 24 213 2.8E-11 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TSH58p_29045 1bac0bd764b724cddaf1cb77e42d51be 254 SUPERFAMILY SSF56300 17 246 5.32E-47 T 14-10-2018 TSH58p_13065 baddc369223e05701e676167f5328615 266 Pfam PF00005 ABC transporter 31 172 7.3E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_13065 baddc369223e05701e676167f5328615 266 Gene3D G3DSA:3.40.50.300 1 254 2.0E-67 T 14-10-2018 TSH58p_13065 baddc369223e05701e676167f5328615 266 SUPERFAMILY SSF52540 7 237 6.68E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_13065 baddc369223e05701e676167f5328615 266 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_13065 baddc369223e05701e676167f5328615 266 SMART SM00382 39 221 1.3E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_06600 4454dad40e4bd00fd9e856bb032c9eed 636 Gene3D G3DSA:3.40.50.2000 420 601 3.9E-124 T 14-10-2018 TSH58p_06600 4454dad40e4bd00fd9e856bb032c9eed 636 Gene3D G3DSA:1.25.40.10 152 249 1.0E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_06600 4454dad40e4bd00fd9e856bb032c9eed 636 Pfam PF13844 Glycosyl transferase family 41 266 395 6.8E-31 T 14-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 TSH58p_06600 4454dad40e4bd00fd9e856bb032c9eed 636 Pfam PF13844 Glycosyl transferase family 41 436 619 8.7E-16 T 14-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 TSH58p_06600 4454dad40e4bd00fd9e856bb032c9eed 636 Pfam PF13176 Tetratricopeptide repeat 120 148 0.0028 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_06600 4454dad40e4bd00fd9e856bb032c9eed 636 Pfam PF13432 Tetratricopeptide repeat 17 76 3.3E-5 T 14-10-2018 TSH58p_06600 4454dad40e4bd00fd9e856bb032c9eed 636 Gene3D G3DSA:1.25.40.10 86 151 1.6E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_06600 4454dad40e4bd00fd9e856bb032c9eed 636 Gene3D G3DSA:3.40.50.11380 254 608 3.9E-124 T 14-10-2018 TSH58p_06600 4454dad40e4bd00fd9e856bb032c9eed 636 SUPERFAMILY SSF53756 456 589 5.23E-6 T 14-10-2018 TSH58p_06600 4454dad40e4bd00fd9e856bb032c9eed 636 SMART SM00028 11 44 0.13 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_06600 4454dad40e4bd00fd9e856bb032c9eed 636 SMART SM00028 116 149 18.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_06600 4454dad40e4bd00fd9e856bb032c9eed 636 SMART SM00028 82 115 1.4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_06600 4454dad40e4bd00fd9e856bb032c9eed 636 SMART SM00028 150 183 21.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_06600 4454dad40e4bd00fd9e856bb032c9eed 636 SMART SM00028 45 78 190.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_06600 4454dad40e4bd00fd9e856bb032c9eed 636 SUPERFAMILY SSF48452 7 193 8.16E-27 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_06600 4454dad40e4bd00fd9e856bb032c9eed 636 Gene3D G3DSA:1.25.40.10 5 85 2.5E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_11805 5980d731462a9fff50b962d86bacb393 313 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 4 83 2.1E-23 T 14-10-2018 IPR013589 Bacterial transglutaminase-like, N-terminal TSH58p_11805 5980d731462a9fff50b962d86bacb393 313 SMART SM00460 177 248 2.5E-20 T 14-10-2018 IPR002931 Transglutaminase-like TSH58p_11805 5980d731462a9fff50b962d86bacb393 313 SUPERFAMILY SSF54001 7 274 2.94E-39 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily TSH58p_11805 5980d731462a9fff50b962d86bacb393 313 Gene3D G3DSA:3.10.620.30 99 285 3.3E-35 T 14-10-2018 TSH58p_11805 5980d731462a9fff50b962d86bacb393 313 Pfam PF01841 Transglutaminase-like superfamily 143 246 2.5E-21 T 14-10-2018 IPR002931 Transglutaminase-like TSH58p_05295 1c45adec5937555fc2b712cfd6dcd6a2 160 Gene3D G3DSA:3.30.230.10 32 160 9.2E-51 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSH58p_05295 1c45adec5937555fc2b712cfd6dcd6a2 160 SUPERFAMILY SSF54211 35 160 3.22E-48 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSH58p_05295 1c45adec5937555fc2b712cfd6dcd6a2 160 Pfam PF00380 Ribosomal protein S9/S16 40 160 1.8E-46 T 14-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 TSH58p_05295 1c45adec5937555fc2b712cfd6dcd6a2 160 ProSitePatterns PS00360 Ribosomal protein S9 signature. 99 117 - T 14-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 TSH58p_05295 1c45adec5937555fc2b712cfd6dcd6a2 160 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 31 160 32.789 T 14-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid TSH58p_10270 89c3dda7f3bc271be965453860ee2fca 334 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 221 230 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site TSH58p_10270 89c3dda7f3bc271be965453860ee2fca 334 Pfam PF00158 Sigma-54 interaction domain 8 169 8.6E-57 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 TSH58p_10270 89c3dda7f3bc271be965453860ee2fca 334 Gene3D G3DSA:1.10.10.60 267 330 2.9E-8 T 14-10-2018 TSH58p_10270 89c3dda7f3bc271be965453860ee2fca 334 Gene3D G3DSA:3.40.50.300 2 178 3.2E-56 T 14-10-2018 TSH58p_10270 89c3dda7f3bc271be965453860ee2fca 334 SUPERFAMILY SSF52540 8 241 4.05E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_10270 89c3dda7f3bc271be965453860ee2fca 334 SUPERFAMILY SSF46689 221 329 5.38E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_10270 89c3dda7f3bc271be965453860ee2fca 334 Gene3D G3DSA:1.10.8.60 179 260 3.1E-21 T 14-10-2018 TSH58p_10270 89c3dda7f3bc271be965453860ee2fca 334 TIGRFAM TIGR02974 phageshock_pspF: psp operon transcriptional activator 8 327 2.6E-144 T 14-10-2018 IPR014317 Transcription activator PspF TSH58p_10270 89c3dda7f3bc271be965453860ee2fca 334 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 94 109 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 TSH58p_10270 89c3dda7f3bc271be965453860ee2fca 334 SMART SM00382 28 178 1.2E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_10270 89c3dda7f3bc271be965453860ee2fca 334 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 310 330 1.6E-5 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_10270 89c3dda7f3bc271be965453860ee2fca 334 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 293 310 1.6E-5 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_10270 89c3dda7f3bc271be965453860ee2fca 334 Pfam PF02954 Bacterial regulatory protein, Fis family 287 326 5.0E-7 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_15275 01f46caea07780ce0ba9d8734ab7f39e 258 Pfam PF07729 FCD domain 110 232 1.1E-24 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_15275 01f46caea07780ce0ba9d8734ab7f39e 258 SMART SM00895 110 234 8.4E-22 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_15275 01f46caea07780ce0ba9d8734ab7f39e 258 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 86 3.3E-20 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_15275 01f46caea07780ce0ba9d8734ab7f39e 258 Gene3D G3DSA:1.20.120.530 105 247 9.6E-29 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_15275 01f46caea07780ce0ba9d8734ab7f39e 258 SMART SM00345 27 86 6.9E-22 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_15275 01f46caea07780ce0ba9d8734ab7f39e 258 SUPERFAMILY SSF48008 107 240 2.17E-25 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_15275 01f46caea07780ce0ba9d8734ab7f39e 258 SUPERFAMILY SSF46785 19 90 1.39E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_15275 01f46caea07780ce0ba9d8734ab7f39e 258 Gene3D G3DSA:1.10.10.10 18 90 8.9E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_15275 01f46caea07780ce0ba9d8734ab7f39e 258 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 60 76 1.6E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_15275 01f46caea07780ce0ba9d8734ab7f39e 258 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 60 1.6E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_27950 0027c4b8884b1a8dcf2880aca8298b6b 159 Pfam PF05258 Protein of unknown function (DUF721) 7 99 3.2E-17 T 14-10-2018 IPR007922 Protein of unknown function DUF721/UPF0232 TSH58p_27950 0027c4b8884b1a8dcf2880aca8298b6b 159 PIRSF PIRSF032064 1 154 1.6E-33 T 14-10-2018 IPR010593 Protein of unknown function DUF1159 TSH58p_20345 ea85f2b67fa69681e6443317393ebe81 340 SUPERFAMILY SSF51735 1 179 1.26E-63 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_20345 ea85f2b67fa69681e6443317393ebe81 340 SUPERFAMILY SSF55347 158 320 9.23E-70 T 14-10-2018 TSH58p_20345 ea85f2b67fa69681e6443317393ebe81 340 Gene3D G3DSA:3.40.50.720 4 331 5.1E-151 T 14-10-2018 TSH58p_20345 ea85f2b67fa69681e6443317393ebe81 340 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 163 319 2.7E-65 T 14-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_20345 ea85f2b67fa69681e6443317393ebe81 340 PIRSF PIRSF000149 1 340 4.8E-138 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_20345 ea85f2b67fa69681e6443317393ebe81 340 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 109 9.2E-38 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_20345 ea85f2b67fa69681e6443317393ebe81 340 SMART SM00846 3 158 2.3E-96 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_20345 ea85f2b67fa69681e6443317393ebe81 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 235 252 4.4E-38 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_20345 ea85f2b67fa69681e6443317393ebe81 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 116 129 4.4E-38 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_20345 ea85f2b67fa69681e6443317393ebe81 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 275 290 4.4E-38 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_20345 ea85f2b67fa69681e6443317393ebe81 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 179 195 4.4E-38 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_20345 ea85f2b67fa69681e6443317393ebe81 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 152 170 4.4E-38 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_20345 ea85f2b67fa69681e6443317393ebe81 340 Gene3D G3DSA:3.30.360.10 157 321 5.1E-151 T 14-10-2018 TSH58p_20345 ea85f2b67fa69681e6443317393ebe81 340 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 330 3.6E-132 T 14-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_20345 ea85f2b67fa69681e6443317393ebe81 340 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 156 163 - T 14-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_31020 fb318840ff6d8f4ae6dd18e08bdd4b7f 499 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 263 270 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 TSH58p_31020 fb318840ff6d8f4ae6dd18e08bdd4b7f 499 Gene3D G3DSA:3.40.605.10 25 491 9.9E-163 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TSH58p_31020 fb318840ff6d8f4ae6dd18e08bdd4b7f 499 Pfam PF00171 Aldehyde dehydrogenase family 34 494 2.1E-156 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TSH58p_31020 fb318840ff6d8f4ae6dd18e08bdd4b7f 499 Gene3D G3DSA:3.40.309.10 268 463 9.9E-163 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TSH58p_31020 fb318840ff6d8f4ae6dd18e08bdd4b7f 499 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 292 303 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 TSH58p_31020 fb318840ff6d8f4ae6dd18e08bdd4b7f 499 SUPERFAMILY SSF53720 22 497 1.02E-151 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSH58p_28255 c5fe80598c02109a0a147ef24ffccd7b 149 SUPERFAMILY SSF102400 1 139 9.02E-44 T 14-10-2018 IPR036768 DNA polymerase III subunit chi superfamily TSH58p_28255 c5fe80598c02109a0a147ef24ffccd7b 149 Gene3D G3DSA:3.40.50.10110 1 138 1.5E-25 T 14-10-2018 IPR036768 DNA polymerase III subunit chi superfamily TSH58p_28255 c5fe80598c02109a0a147ef24ffccd7b 149 Pfam PF04364 DNA polymerase III chi subunit, HolC 1 135 2.0E-38 T 14-10-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 TSH58p_25955 12adee9fc283a5cb267ec87894b4f590 184 PRINTS PR00502 NUDIX hydrolase family signature 93 108 3.4E-6 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TSH58p_25955 12adee9fc283a5cb267ec87894b4f590 184 PRINTS PR00502 NUDIX hydrolase family signature 79 93 3.4E-6 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TSH58p_25955 12adee9fc283a5cb267ec87894b4f590 184 SUPERFAMILY SSF55811 45 176 4.87E-29 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TSH58p_25955 12adee9fc283a5cb267ec87894b4f590 184 ProSitePatterns PS00893 Nudix box signature. 84 105 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TSH58p_25955 12adee9fc283a5cb267ec87894b4f590 184 Gene3D G3DSA:3.90.79.10 36 178 2.4E-26 T 14-10-2018 TSH58p_25955 12adee9fc283a5cb267ec87894b4f590 184 Pfam PF00293 NUDIX domain 50 168 1.8E-17 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TSH58p_29370 4fc82bced279945804d451a1ede839c2 533 Gene3D G3DSA:3.40.190.10 207 520 3.1E-181 T 14-10-2018 TSH58p_29370 4fc82bced279945804d451a1ede839c2 533 SUPERFAMILY SSF53850 26 530 1.34E-160 T 14-10-2018 TSH58p_29370 4fc82bced279945804d451a1ede839c2 533 Gene3D G3DSA:3.90.76.10 49 206 3.1E-181 T 14-10-2018 TSH58p_29370 4fc82bced279945804d451a1ede839c2 533 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 75 97 - T 14-10-2018 IPR023765 Solute-binding protein family 5, conserved site TSH58p_29370 4fc82bced279945804d451a1ede839c2 533 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 69 448 7.7E-107 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain TSH58p_29370 4fc82bced279945804d451a1ede839c2 533 Gene3D G3DSA:3.10.105.10 288 507 3.1E-181 T 14-10-2018 TSH58p_29370 4fc82bced279945804d451a1ede839c2 533 PIRSF PIRSF002741 5 532 5.1E-126 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TSH58p_17065 fce510faa96ca031d44ab04e991ad077 174 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 6 167 1.8E-60 T 14-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 TSH58p_17065 fce510faa96ca031d44ab04e991ad077 174 SUPERFAMILY SSF52540 5 170 1.49E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_17065 fce510faa96ca031d44ab04e991ad077 174 PIRSF PIRSF006135 4 172 7.2E-55 T 14-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 TSH58p_17065 fce510faa96ca031d44ab04e991ad077 174 Gene3D G3DSA:3.40.50.300 5 170 1.3E-56 T 14-10-2018 TSH58p_19390 1831180c807e905e54c9402ccd4c06ef 249 SUPERFAMILY SSF52402 1 242 5.38E-89 T 14-10-2018 TSH58p_19390 1831180c807e905e54c9402ccd4c06ef 249 Gene3D G3DSA:3.40.50.620 1 247 6.4E-92 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_19390 1831180c807e905e54c9402ccd4c06ef 249 Pfam PF01012 Electron transfer flavoprotein domain 26 206 4.2E-51 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 TSH58p_19390 1831180c807e905e54c9402ccd4c06ef 249 SMART SM00893 23 211 4.9E-71 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 TSH58p_19390 1831180c807e905e54c9402ccd4c06ef 249 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 14-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 TSH58p_19390 1831180c807e905e54c9402ccd4c06ef 249 PIRSF PIRSF000090 1 249 4.1E-90 T 14-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 TSH58p_05225 5e5e9a5f7ea439810043e9c395c73c7a 279 SUPERFAMILY SSF51430 4 275 4.45E-79 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TSH58p_05225 5e5e9a5f7ea439810043e9c395c73c7a 279 Pfam PF00248 Aldo/keto reductase family 17 265 1.4E-51 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain TSH58p_05225 5e5e9a5f7ea439810043e9c395c73c7a 279 Gene3D G3DSA:3.20.20.100 1 279 1.1E-96 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TSH58p_05225 5e5e9a5f7ea439810043e9c395c73c7a 279 PRINTS PR00069 Aldo-keto reductase signature 127 144 2.5E-14 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TSH58p_05225 5e5e9a5f7ea439810043e9c395c73c7a 279 PRINTS PR00069 Aldo-keto reductase signature 201 225 2.5E-14 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TSH58p_05225 5e5e9a5f7ea439810043e9c395c73c7a 279 PRINTS PR00069 Aldo-keto reductase signature 97 115 2.5E-14 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TSH58p_18045 7dc9492dbd0845d84cf455abbf559cd5 294 SMART SM00470 34 123 1.3E-20 T 14-10-2018 IPR003115 ParB/Sulfiredoxin TSH58p_18045 7dc9492dbd0845d84cf455abbf559cd5 294 Gene3D G3DSA:1.10.10.2830 112 216 2.1E-16 T 14-10-2018 TSH58p_18045 7dc9492dbd0845d84cf455abbf559cd5 294 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 37 205 3.4E-31 T 14-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 TSH58p_18045 7dc9492dbd0845d84cf455abbf559cd5 294 Gene3D G3DSA:3.90.1530.30 47 108 7.8E-20 T 14-10-2018 TSH58p_18045 7dc9492dbd0845d84cf455abbf559cd5 294 SUPERFAMILY SSF109709 116 213 7.06E-18 T 14-10-2018 TSH58p_18045 7dc9492dbd0845d84cf455abbf559cd5 294 Pfam PF02195 ParB-like nuclease domain 38 121 3.5E-17 T 14-10-2018 IPR003115 ParB/Sulfiredoxin TSH58p_18045 7dc9492dbd0845d84cf455abbf559cd5 294 SUPERFAMILY SSF110849 34 126 5.93E-22 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily TSH58p_11170 30e9940f107fc412ea4c8c1639cefdf7 542 Gene3D G3DSA:3.40.50.300 326 531 3.0E-43 T 14-10-2018 TSH58p_11170 30e9940f107fc412ea4c8c1639cefdf7 542 SMART SM00382 34 216 1.7E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_11170 30e9940f107fc412ea4c8c1639cefdf7 542 SMART SM00382 367 535 1.6E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_11170 30e9940f107fc412ea4c8c1639cefdf7 542 SUPERFAMILY SSF52540 328 520 5.62E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_11170 30e9940f107fc412ea4c8c1639cefdf7 542 SUPERFAMILY SSF52540 10 223 1.4E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_11170 30e9940f107fc412ea4c8c1639cefdf7 542 Pfam PF00005 ABC transporter 36 172 6.2E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_11170 30e9940f107fc412ea4c8c1639cefdf7 542 Pfam PF00005 ABC transporter 359 488 1.7E-16 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_11170 30e9940f107fc412ea4c8c1639cefdf7 542 Gene3D G3DSA:3.40.50.300 8 273 1.2E-46 T 14-10-2018 TSH58p_11170 30e9940f107fc412ea4c8c1639cefdf7 542 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_30650 dde6111787eba2c5d41054972b2049bc 698 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 20 197 9.2E-58 T 14-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 TSH58p_30650 dde6111787eba2c5d41054972b2049bc 698 Pfam PF01968 Hydantoinase/oxoprolinase 218 502 9.5E-96 T 14-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 TSH58p_30650 dde6111787eba2c5d41054972b2049bc 698 SUPERFAMILY SSF53067 20 320 2.31E-5 T 14-10-2018 TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 448 552 4.4E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1012 1132 4.7E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 SUPERFAMILY SSF52172 616 746 7.97E-39 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 SUPERFAMILY SSF55874 960 1133 8.51E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 SUPERFAMILY SSF47384 892 967 1.9E-8 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 SUPERFAMILY SSF55874 385 551 2.62E-44 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 Gene3D G3DSA:1.10.287.130 316 399 7.9E-22 T 14-10-2018 TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 SUPERFAMILY SSF47384 317 397 4.12E-16 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1063 1077 2.4E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1081 1091 2.4E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1118 1131 2.4E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1094 1112 2.4E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 Gene3D G3DSA:3.30.565.10 972 1142 1.2E-42 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 Pfam PF00072 Response regulator receiver domain 1307 1388 4.9E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 Pfam PF00072 Response regulator receiver domain 1155 1266 1.7E-11 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 Pfam PF00072 Response regulator receiver domain 619 728 3.3E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 Gene3D G3DSA:3.40.50.2300 1152 1279 1.1E-22 T 14-10-2018 TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 SMART SM00387 442 553 1.6E-32 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 SMART SM00387 1011 1134 4.7E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 Gene3D G3DSA:3.30.450.40 150 315 4.0E-8 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 Gene3D G3DSA:3.30.450.20 745 862 6.7E-32 T 14-10-2018 TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 SMART SM00086 822 864 6.5E-10 T 14-10-2018 IPR001610 PAC motif TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 SMART SM00086 99 143 140.0 T 14-10-2018 IPR001610 PAC motif TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 SUPERFAMILY SSF55785 738 862 5.96E-29 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 746 869 8.1E-23 T 14-10-2018 IPR000014 PAS domain TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 Pfam PF00512 His Kinase A (phospho-acceptor) domain 330 396 8.3E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 Pfam PF00512 His Kinase A (phospho-acceptor) domain 906 968 1.4E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 SMART SM00448 1305 1408 1.3E-17 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 SMART SM00448 1153 1266 2.5E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 SMART SM00448 616 728 7.3E-40 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 SMART SM00091 750 816 6.4E-7 T 14-10-2018 IPR000014 PAS domain TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 Gene3D G3DSA:1.10.287.130 896 968 1.3E-19 T 14-10-2018 TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 Gene3D G3DSA:3.40.50.2300 603 744 1.8E-39 T 14-10-2018 TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 SUPERFAMILY SSF52172 1153 1277 6.4E-24 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 Gene3D G3DSA:3.30.450.20 23 149 4.0E-13 T 14-10-2018 TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 SUPERFAMILY SSF52172 1303 1413 3.13E-27 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 Gene3D G3DSA:3.40.50.2300 1300 1414 5.3E-24 T 14-10-2018 TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 SMART SM00388 904 970 1.7E-6 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 SMART SM00388 329 396 2.4E-17 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 SUPERFAMILY SSF55781 172 320 1.32E-10 T 14-10-2018 TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 Pfam PF08447 PAS fold 774 857 5.1E-17 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 TSH58p_32200 3eb6b26dd46ea3f6e884ee0ea474aa8f 1416 Gene3D G3DSA:3.30.565.10 402 552 1.1E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_25895 b2b9cb76f073384886e6150bb2c81d91 253 Gene3D G3DSA:3.40.50.150 18 252 1.5E-70 T 14-10-2018 TSH58p_25895 b2b9cb76f073384886e6150bb2c81d91 253 Pfam PF08241 Methyltransferase domain 74 168 8.7E-19 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TSH58p_25895 b2b9cb76f073384886e6150bb2c81d91 253 SUPERFAMILY SSF53335 20 251 2.07E-42 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_25895 b2b9cb76f073384886e6150bb2c81d91 253 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 18 253 39.116 T 14-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 TSH58p_25895 b2b9cb76f073384886e6150bb2c81d91 253 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 19 247 2.6E-84 T 14-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 TSH58p_21000 5e612151eaf83610553c123c504a10f2 351 SMART SM00421 283 340 1.7E-6 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_21000 5e612151eaf83610553c123c504a10f2 351 Gene3D G3DSA:1.10.10.10 270 344 1.1E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_21000 5e612151eaf83610553c123c504a10f2 351 SUPERFAMILY SSF46894 275 341 1.46E-11 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_28370 f321f21f82718f7490d708b7d1bdff5d 186 Pfam PF01066 CDP-alcohol phosphatidyltransferase 3 66 1.0E-13 T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TSH58p_28370 f321f21f82718f7490d708b7d1bdff5d 186 Gene3D G3DSA:1.20.120.1760 2 176 2.9E-12 T 14-10-2018 TSH58p_28370 f321f21f82718f7490d708b7d1bdff5d 186 PIRSF PIRSF000847 1 183 2.3E-37 T 14-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 TSH58p_28370 f321f21f82718f7490d708b7d1bdff5d 186 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 44 66 - T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TSH58p_09005 d0eeb47b06218165f44e67dfa1cbab56 346 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 167 185 6.8E-41 T 14-10-2018 TSH58p_09005 d0eeb47b06218165f44e67dfa1cbab56 346 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 275 6.8E-41 T 14-10-2018 TSH58p_09005 d0eeb47b06218165f44e67dfa1cbab56 346 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 27 46 6.8E-41 T 14-10-2018 TSH58p_09005 d0eeb47b06218165f44e67dfa1cbab56 346 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 125 143 6.8E-41 T 14-10-2018 TSH58p_09005 d0eeb47b06218165f44e67dfa1cbab56 346 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 286 308 6.8E-41 T 14-10-2018 TSH58p_09005 d0eeb47b06218165f44e67dfa1cbab56 346 Gene3D G3DSA:3.50.50.60 137 267 1.9E-123 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_09005 d0eeb47b06218165f44e67dfa1cbab56 346 Gene3D G3DSA:3.50.50.60 27 327 1.9E-123 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_09005 d0eeb47b06218165f44e67dfa1cbab56 346 SUPERFAMILY SSF51905 19 333 8.64E-56 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_09005 d0eeb47b06218165f44e67dfa1cbab56 346 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 155 175 - T 14-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 TSH58p_09005 d0eeb47b06218165f44e67dfa1cbab56 346 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 26 322 1.2E-54 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSH58p_09005 d0eeb47b06218165f44e67dfa1cbab56 346 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 26 333 1.5E-126 T 14-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 TSH58p_09005 d0eeb47b06218165f44e67dfa1cbab56 346 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 59 74 4.0E-80 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_09005 d0eeb47b06218165f44e67dfa1cbab56 346 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 126 134 4.0E-80 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_09005 d0eeb47b06218165f44e67dfa1cbab56 346 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 148 160 4.0E-80 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_09005 d0eeb47b06218165f44e67dfa1cbab56 346 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 296 314 4.0E-80 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_09005 d0eeb47b06218165f44e67dfa1cbab56 346 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 26 48 4.0E-80 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_09005 d0eeb47b06218165f44e67dfa1cbab56 346 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 80 90 4.0E-80 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_09005 d0eeb47b06218165f44e67dfa1cbab56 346 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 163 187 4.0E-80 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_09005 d0eeb47b06218165f44e67dfa1cbab56 346 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 215 231 4.0E-80 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_09005 d0eeb47b06218165f44e67dfa1cbab56 346 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 261 282 4.0E-80 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_29890 6bc006ed18eb25d1243aa8157607a489 465 Gene3D G3DSA:3.50.50.60 152 273 1.2E-116 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_29890 6bc006ed18eb25d1243aa8157607a489 465 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 14-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 TSH58p_29890 6bc006ed18eb25d1243aa8157607a489 465 Gene3D G3DSA:3.50.50.60 6 332 1.2E-116 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_29890 6bc006ed18eb25d1243aa8157607a489 465 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 346 454 2.2E-37 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TSH58p_29890 6bc006ed18eb25d1243aa8157607a489 465 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 326 7.2E-66 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSH58p_29890 6bc006ed18eb25d1243aa8157607a489 465 SUPERFAMILY SSF51905 2 371 6.83E-67 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_29890 6bc006ed18eb25d1243aa8157607a489 465 Gene3D G3DSA:3.30.390.30 345 465 6.0E-44 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TSH58p_29890 6bc006ed18eb25d1243aa8157607a489 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 306 313 5.3E-72 T 14-10-2018 TSH58p_29890 6bc006ed18eb25d1243aa8157607a489 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 5.3E-72 T 14-10-2018 TSH58p_29890 6bc006ed18eb25d1243aa8157607a489 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 429 449 5.3E-72 T 14-10-2018 TSH58p_29890 6bc006ed18eb25d1243aa8157607a489 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 176 201 5.3E-72 T 14-10-2018 TSH58p_29890 6bc006ed18eb25d1243aa8157607a489 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 5.3E-72 T 14-10-2018 TSH58p_29890 6bc006ed18eb25d1243aa8157607a489 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 407 422 5.3E-72 T 14-10-2018 TSH58p_29890 6bc006ed18eb25d1243aa8157607a489 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 264 278 5.3E-72 T 14-10-2018 TSH58p_29890 6bc006ed18eb25d1243aa8157607a489 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 140 149 5.3E-72 T 14-10-2018 TSH58p_29890 6bc006ed18eb25d1243aa8157607a489 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 342 363 5.3E-72 T 14-10-2018 TSH58p_29890 6bc006ed18eb25d1243aa8157607a489 465 PIRSF PIRSF000350 1 459 1.3E-86 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 TSH58p_29890 6bc006ed18eb25d1243aa8157607a489 465 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 5 465 1.0E-179 T 14-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 TSH58p_29890 6bc006ed18eb25d1243aa8157607a489 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 176 194 1.6E-42 T 14-10-2018 TSH58p_29890 6bc006ed18eb25d1243aa8157607a489 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 279 1.6E-42 T 14-10-2018 TSH58p_29890 6bc006ed18eb25d1243aa8157607a489 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.6E-42 T 14-10-2018 TSH58p_29890 6bc006ed18eb25d1243aa8157607a489 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 1.6E-42 T 14-10-2018 TSH58p_29890 6bc006ed18eb25d1243aa8157607a489 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 291 313 1.6E-42 T 14-10-2018 TSH58p_29890 6bc006ed18eb25d1243aa8157607a489 465 SUPERFAMILY SSF55424 342 464 5.15E-41 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TSH58p_10865 008582de036964bc6756117d29971087 151 Gene3D G3DSA:2.60.120.10 1 148 3.0E-36 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_10865 008582de036964bc6756117d29971087 151 SMART SM00100 15 132 5.9E-21 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_10865 008582de036964bc6756117d29971087 151 SUPERFAMILY SSF51206 8 142 5.63E-34 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like TSH58p_10865 008582de036964bc6756117d29971087 151 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 82 99 - T 14-10-2018 IPR018488 Cyclic nucleotide-binding, conserved site TSH58p_10865 008582de036964bc6756117d29971087 151 PRINTS PR00103 cAMP-dependent protein kinase signature 51 65 5.6E-5 T 14-10-2018 TSH58p_10865 008582de036964bc6756117d29971087 151 PRINTS PR00103 cAMP-dependent protein kinase signature 92 103 5.6E-5 T 14-10-2018 TSH58p_10865 008582de036964bc6756117d29971087 151 PRINTS PR00103 cAMP-dependent protein kinase signature 36 50 5.6E-5 T 14-10-2018 TSH58p_10865 008582de036964bc6756117d29971087 151 PRINTS PR00103 cAMP-dependent protein kinase signature 80 89 5.6E-5 T 14-10-2018 TSH58p_10865 008582de036964bc6756117d29971087 151 Pfam PF00027 Cyclic nucleotide-binding domain 34 118 7.8E-21 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_10365 7c3e65ed92ad75e4fe9c1d53eca58201 567 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 471 551 1.6E-15 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_10365 7c3e65ed92ad75e4fe9c1d53eca58201 567 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 473 531 9.9E-9 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_10365 7c3e65ed92ad75e4fe9c1d53eca58201 567 SUPERFAMILY SSF52540 240 492 4.5E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_10365 7c3e65ed92ad75e4fe9c1d53eca58201 567 SUPERFAMILY SSF52540 9 216 4.85E-27 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_10365 7c3e65ed92ad75e4fe9c1d53eca58201 567 Pfam PF00005 ABC transporter 266 421 2.2E-19 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_10365 7c3e65ed92ad75e4fe9c1d53eca58201 567 Pfam PF00005 ABC transporter 25 163 2.7E-12 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_10365 7c3e65ed92ad75e4fe9c1d53eca58201 567 Gene3D G3DSA:3.40.50.300 10 224 2.3E-26 T 14-10-2018 TSH58p_10365 7c3e65ed92ad75e4fe9c1d53eca58201 567 Gene3D G3DSA:3.40.50.300 238 563 1.3E-64 T 14-10-2018 TSH58p_10365 7c3e65ed92ad75e4fe9c1d53eca58201 567 SMART SM00382 34 215 4.3E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_10365 7c3e65ed92ad75e4fe9c1d53eca58201 567 SMART SM00382 274 471 2.2E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_10525 fff266c49d7ffbe80237a2d43091f149 554 Pfam PF12860 PAS fold 181 294 1.5E-21 T 14-10-2018 TSH58p_10525 fff266c49d7ffbe80237a2d43091f149 554 SUPERFAMILY SSF47384 296 379 6.28E-22 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_10525 fff266c49d7ffbe80237a2d43091f149 554 Pfam PF00512 His Kinase A (phospho-acceptor) domain 311 378 4.0E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_10525 fff266c49d7ffbe80237a2d43091f149 554 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 424 543 1.3E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_10525 fff266c49d7ffbe80237a2d43091f149 554 SMART SM00388 310 378 9.1E-18 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_10525 fff266c49d7ffbe80237a2d43091f149 554 Gene3D G3DSA:1.10.287.130 301 378 2.7E-22 T 14-10-2018 TSH58p_10525 fff266c49d7ffbe80237a2d43091f149 554 Gene3D G3DSA:3.30.565.10 379 546 2.2E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_10525 fff266c49d7ffbe80237a2d43091f149 554 SUPERFAMILY SSF55785 159 288 9.07E-9 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_10525 fff266c49d7ffbe80237a2d43091f149 554 SUPERFAMILY SSF55874 367 544 3.67E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_10525 fff266c49d7ffbe80237a2d43091f149 554 SMART SM00387 424 546 2.0E-30 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_10525 fff266c49d7ffbe80237a2d43091f149 554 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 477 8.1E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_10525 fff266c49d7ffbe80237a2d43091f149 554 PRINTS PR00344 Bacterial sensor protein C-terminal signature 530 543 8.1E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_10525 fff266c49d7ffbe80237a2d43091f149 554 PRINTS PR00344 Bacterial sensor protein C-terminal signature 506 524 8.1E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_10525 fff266c49d7ffbe80237a2d43091f149 554 Gene3D G3DSA:3.30.450.20 25 170 2.4E-5 T 14-10-2018 TSH58p_10525 fff266c49d7ffbe80237a2d43091f149 554 Gene3D G3DSA:3.30.450.20 171 300 5.8E-7 T 14-10-2018 TSH58p_04530 334dc4e1b28e0b21d18b669f5e1948a1 516 SUPERFAMILY SSF52374 4 350 4.29E-113 T 14-10-2018 TSH58p_04530 334dc4e1b28e0b21d18b669f5e1948a1 516 SUPERFAMILY SSF47323 353 509 2.43E-41 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_04530 334dc4e1b28e0b21d18b669f5e1948a1 516 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 509 48.166 T 14-10-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TSH58p_04530 334dc4e1b28e0b21d18b669f5e1948a1 516 Gene3D G3DSA:1.10.730.10 341 514 1.1E-52 T 14-10-2018 TSH58p_04530 334dc4e1b28e0b21d18b669f5e1948a1 516 PRINTS PR01041 Methionyl-tRNA synthetase signature 89 100 2.2E-32 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TSH58p_04530 334dc4e1b28e0b21d18b669f5e1948a1 516 PRINTS PR01041 Methionyl-tRNA synthetase signature 9 22 2.2E-32 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TSH58p_04530 334dc4e1b28e0b21d18b669f5e1948a1 516 PRINTS PR01041 Methionyl-tRNA synthetase signature 260 275 2.2E-32 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TSH58p_04530 334dc4e1b28e0b21d18b669f5e1948a1 516 PRINTS PR01041 Methionyl-tRNA synthetase signature 352 363 2.2E-32 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TSH58p_04530 334dc4e1b28e0b21d18b669f5e1948a1 516 PRINTS PR01041 Methionyl-tRNA synthetase signature 41 55 2.2E-32 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TSH58p_04530 334dc4e1b28e0b21d18b669f5e1948a1 516 PRINTS PR01041 Methionyl-tRNA synthetase signature 228 239 2.2E-32 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TSH58p_04530 334dc4e1b28e0b21d18b669f5e1948a1 516 Gene3D G3DSA:3.40.50.620 7 337 3.3E-155 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_04530 334dc4e1b28e0b21d18b669f5e1948a1 516 Gene3D G3DSA:2.170.220.10 118 230 3.3E-155 T 14-10-2018 TSH58p_04530 334dc4e1b28e0b21d18b669f5e1948a1 516 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 7 477 6.0E-158 T 14-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TSH58p_04530 334dc4e1b28e0b21d18b669f5e1948a1 516 Pfam PF09334 tRNA synthetases class I (M) 7 364 6.5E-111 T 14-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_26900 a8bc4f0a6dcf91a2f5e11fa9c17020ea 360 Gene3D G3DSA:3.40.190.10 41 357 1.0E-100 T 14-10-2018 TSH58p_26900 a8bc4f0a6dcf91a2f5e11fa9c17020ea 360 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 9 30 1.0E-5 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal TSH58p_26900 a8bc4f0a6dcf91a2f5e11fa9c17020ea 360 Gene3D G3DSA:3.40.190.10 144 267 1.0E-100 T 14-10-2018 TSH58p_26900 a8bc4f0a6dcf91a2f5e11fa9c17020ea 360 Pfam PF13416 Bacterial extracellular solute-binding protein 59 304 3.7E-33 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSH58p_26900 a8bc4f0a6dcf91a2f5e11fa9c17020ea 360 SUPERFAMILY SSF53850 48 357 3.18E-52 T 14-10-2018 TSH58p_07860 ac6535e76b53fb4ffeac1fc7e49b39ff 436 SUPERFAMILY SSF58104 83 428 4.84E-58 T 14-10-2018 TSH58p_07860 ac6535e76b53fb4ffeac1fc7e49b39ff 436 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 257 415 9.2E-29 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_07860 ac6535e76b53fb4ffeac1fc7e49b39ff 436 Gene3D G3DSA:1.10.287.950 138 436 3.4E-52 T 14-10-2018 TSH58p_07860 ac6535e76b53fb4ffeac1fc7e49b39ff 436 SMART SM00283 175 429 6.3E-37 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_07860 ac6535e76b53fb4ffeac1fc7e49b39ff 436 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 302 331 4.7E-17 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_07860 ac6535e76b53fb4ffeac1fc7e49b39ff 436 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 273 300 4.7E-17 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_07860 ac6535e76b53fb4ffeac1fc7e49b39ff 436 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 196 225 4.7E-17 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_09750 2debbde56bd2276f27ee353ee6ebaf3f 376 Pfam PF00512 His Kinase A (phospho-acceptor) domain 144 207 8.0E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_09750 2debbde56bd2276f27ee353ee6ebaf3f 376 SUPERFAMILY SSF55874 198 362 1.96E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_09750 2debbde56bd2276f27ee353ee6ebaf3f 376 SUPERFAMILY SSF47384 129 207 4.12E-11 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_09750 2debbde56bd2276f27ee353ee6ebaf3f 376 Gene3D G3DSA:1.10.287.130 109 205 1.1E-11 T 14-10-2018 TSH58p_09750 2debbde56bd2276f27ee353ee6ebaf3f 376 SMART SM00388 142 207 8.1E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_09750 2debbde56bd2276f27ee353ee6ebaf3f 376 Gene3D G3DSA:3.30.565.10 207 366 3.0E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_09750 2debbde56bd2276f27ee353ee6ebaf3f 376 Gene3D G3DSA:3.30.450.20 5 108 2.6E-7 T 14-10-2018 TSH58p_09750 2debbde56bd2276f27ee353ee6ebaf3f 376 Pfam PF08448 PAS fold 20 107 3.1E-7 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_09750 2debbde56bd2276f27ee353ee6ebaf3f 376 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 252 361 6.2E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_09750 2debbde56bd2276f27ee353ee6ebaf3f 376 PRINTS PR00344 Bacterial sensor protein C-terminal signature 322 340 4.6E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_09750 2debbde56bd2276f27ee353ee6ebaf3f 376 PRINTS PR00344 Bacterial sensor protein C-terminal signature 346 359 4.6E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_09750 2debbde56bd2276f27ee353ee6ebaf3f 376 PRINTS PR00344 Bacterial sensor protein C-terminal signature 287 301 4.6E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_09750 2debbde56bd2276f27ee353ee6ebaf3f 376 PRINTS PR00344 Bacterial sensor protein C-terminal signature 305 315 4.6E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_09750 2debbde56bd2276f27ee353ee6ebaf3f 376 SUPERFAMILY SSF55785 7 107 2.44E-9 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_09750 2debbde56bd2276f27ee353ee6ebaf3f 376 SMART SM00387 251 362 1.6E-28 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_18040 64a207bb9e83a245f61ef4069ab9b949 330 Gene3D G3DSA:1.10.260.40 1 61 4.6E-5 T 14-10-2018 TSH58p_18040 64a207bb9e83a245f61ef4069ab9b949 330 Pfam PF13614 AAA domain 66 243 7.5E-52 T 14-10-2018 IPR025669 AAA domain TSH58p_18040 64a207bb9e83a245f61ef4069ab9b949 330 SUPERFAMILY SSF52540 64 317 3.4E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_18040 64a207bb9e83a245f61ef4069ab9b949 330 Gene3D G3DSA:3.40.50.300 62 328 8.4E-69 T 14-10-2018 TSH58p_15030 4535a08cf1a32440758176368b79d718 190 Gene3D G3DSA:3.10.560.10 92 186 4.3E-12 T 14-10-2018 TSH58p_15030 4535a08cf1a32440758176368b79d718 190 Pfam PF02563 Polysaccharide biosynthesis/export protein 37 111 2.8E-20 T 14-10-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 TSH58p_15030 4535a08cf1a32440758176368b79d718 190 Pfam PF10531 SLBB domain 118 160 2.8E-7 T 14-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_13545 154313338cadcd9ad4490d67a95119cd 197 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 14-10-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 TSH58p_13545 154313338cadcd9ad4490d67a95119cd 197 Gene3D G3DSA:1.10.8.420 2 51 4.0E-11 T 14-10-2018 TSH58p_13545 154313338cadcd9ad4490d67a95119cd 197 SUPERFAMILY SSF111304 3 197 4.97E-69 T 14-10-2018 IPR023627 Recombination protein RecR TSH58p_13545 154313338cadcd9ad4490d67a95119cd 197 Hamap MF_00017 Recombination protein RecR [recR]. 1 197 95.879 T 14-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 TSH58p_13545 154313338cadcd9ad4490d67a95119cd 197 Gene3D G3DSA:3.40.1360.10 76 197 6.4E-41 T 14-10-2018 TSH58p_13545 154313338cadcd9ad4490d67a95119cd 197 Pfam PF02132 RecR protein 41 77 3.6E-12 T 14-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger TSH58p_13545 154313338cadcd9ad4490d67a95119cd 197 SMART SM00493 79 164 9.1E-4 T 14-10-2018 IPR006171 TOPRIM domain TSH58p_13545 154313338cadcd9ad4490d67a95119cd 197 Pfam PF13662 Toprim domain 79 170 3.4E-23 T 14-10-2018 IPR006171 TOPRIM domain TSH58p_13545 154313338cadcd9ad4490d67a95119cd 197 TIGRFAM TIGR00615 recR: recombination protein RecR 4 195 1.3E-64 T 14-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 TSH58p_19650 54875028ba2132ab2c97a80fa1ac755e 383 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 53 343 1.8E-43 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TSH58p_19650 54875028ba2132ab2c97a80fa1ac755e 383 Gene3D G3DSA:3.40.50.1100 53 351 6.0E-65 T 14-10-2018 TSH58p_19650 54875028ba2132ab2c97a80fa1ac755e 383 SUPERFAMILY SSF53686 53 364 3.54E-67 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TSH58p_19650 54875028ba2132ab2c97a80fa1ac755e 383 Gene3D G3DSA:3.40.50.1100 80 186 6.0E-65 T 14-10-2018 TSH58p_17080 30e7291921045345607f9ce64c65cb99 693 SMART SM00490 498 580 3.2E-17 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_17080 30e7291921045345607f9ce64c65cb99 693 Pfam PF00270 DEAD/DEAH box helicase 269 426 6.1E-16 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TSH58p_17080 30e7291921045345607f9ce64c65cb99 693 SUPERFAMILY SSF52540 180 445 5.33E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_17080 30e7291921045345607f9ce64c65cb99 693 Pfam PF00271 Helicase conserved C-terminal domain 470 579 4.4E-16 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_17080 30e7291921045345607f9ce64c65cb99 693 Pfam PF17191 RecG wedge domain 18 173 1.2E-7 T 14-10-2018 IPR033454 RecG, wedge domain TSH58p_17080 30e7291921045345607f9ce64c65cb99 693 SUPERFAMILY SSF52540 444 645 6.57E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_17080 30e7291921045345607f9ce64c65cb99 693 Gene3D G3DSA:2.40.50.140 49 141 2.7E-11 T 14-10-2018 TSH58p_17080 30e7291921045345607f9ce64c65cb99 693 Gene3D G3DSA:3.40.50.300 214 442 1.5E-81 T 14-10-2018 TSH58p_17080 30e7291921045345607f9ce64c65cb99 693 SMART SM00487 262 452 1.4E-27 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSH58p_17080 30e7291921045345607f9ce64c65cb99 693 SUPERFAMILY SSF50249 7 176 2.91E-26 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_17080 30e7291921045345607f9ce64c65cb99 693 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 34 656 1.0E-208 T 14-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 TSH58p_17080 30e7291921045345607f9ce64c65cb99 693 Gene3D G3DSA:3.40.50.300 450 621 1.4E-49 T 14-10-2018 TSH58p_09425 6d48c77a6a79455f20a1f84302519c30 322 PIRSF PIRSF000102 1 321 6.6E-109 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TSH58p_09425 6d48c77a6a79455f20a1f84302519c30 322 PRINTS PR00086 L-lactate dehydrogenase signature 171 184 1.5E-31 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TSH58p_09425 6d48c77a6a79455f20a1f84302519c30 322 PRINTS PR00086 L-lactate dehydrogenase signature 29 53 1.5E-31 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TSH58p_09425 6d48c77a6a79455f20a1f84302519c30 322 PRINTS PR00086 L-lactate dehydrogenase signature 117 137 1.5E-31 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TSH58p_09425 6d48c77a6a79455f20a1f84302519c30 322 PRINTS PR00086 L-lactate dehydrogenase signature 5 29 1.5E-31 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TSH58p_09425 6d48c77a6a79455f20a1f84302519c30 322 PRINTS PR00086 L-lactate dehydrogenase signature 141 159 1.5E-31 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TSH58p_09425 6d48c77a6a79455f20a1f84302519c30 322 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 5 143 4.1E-44 T 14-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 TSH58p_09425 6d48c77a6a79455f20a1f84302519c30 322 TIGRFAM TIGR01763 MalateDH_bact: malate dehydrogenase, NAD-dependent 3 311 1.5E-131 T 14-10-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 TSH58p_09425 6d48c77a6a79455f20a1f84302519c30 322 Gene3D G3DSA:3.90.110.10 146 320 5.0E-67 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 TSH58p_09425 6d48c77a6a79455f20a1f84302519c30 322 Hamap MF_00487 Malate dehydrogenase [mdh]. 4 313 47.111 T 14-10-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 TSH58p_09425 6d48c77a6a79455f20a1f84302519c30 322 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 147 314 4.9E-31 T 14-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 TSH58p_09425 6d48c77a6a79455f20a1f84302519c30 322 SUPERFAMILY SSF51735 5 144 6.64E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_09425 6d48c77a6a79455f20a1f84302519c30 322 Gene3D G3DSA:3.40.50.720 1 145 1.8E-57 T 14-10-2018 TSH58p_09425 6d48c77a6a79455f20a1f84302519c30 322 SUPERFAMILY SSF56327 144 312 1.08E-57 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 TSH58p_17745 726c4d1e60a184a0d92b739f0c7b13aa 70 Pfam PF13560 Helix-turn-helix domain 8 55 8.7E-8 T 14-10-2018 TSH58p_17745 726c4d1e60a184a0d92b739f0c7b13aa 70 Gene3D G3DSA:1.10.260.40 1 66 1.5E-14 T 14-10-2018 TSH58p_17745 726c4d1e60a184a0d92b739f0c7b13aa 70 SUPERFAMILY SSF47413 5 54 4.44E-9 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_02185 8d1b34b356ab859db06761a5b98be7e9 308 SUPERFAMILY SSF51735 12 257 8.25E-51 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_02185 8d1b34b356ab859db06761a5b98be7e9 308 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 165 193 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_02185 8d1b34b356ab859db06761a5b98be7e9 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 1.3E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_02185 8d1b34b356ab859db06761a5b98be7e9 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 1.3E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_02185 8d1b34b356ab859db06761a5b98be7e9 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 238 257 1.3E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_02185 8d1b34b356ab859db06761a5b98be7e9 308 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 178 197 4.0E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_02185 8d1b34b356ab859db06761a5b98be7e9 308 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 93 104 4.0E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_02185 8d1b34b356ab859db06761a5b98be7e9 308 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 4.0E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_02185 8d1b34b356ab859db06761a5b98be7e9 308 Pfam PF00106 short chain dehydrogenase 16 219 1.1E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_02185 8d1b34b356ab859db06761a5b98be7e9 308 Gene3D G3DSA:3.40.50.720 1 306 1.0E-77 T 14-10-2018 TSH58p_23865 0d20f01934b9d7d8f73bc45af386b920 84 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 15 68 8.9E-22 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 TSH58p_23865 0d20f01934b9d7d8f73bc45af386b920 84 Pfam PF02609 Exonuclease VII small subunit 16 66 5.8E-19 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 TSH58p_23865 0d20f01934b9d7d8f73bc45af386b920 84 Gene3D G3DSA:1.10.287.1040 11 82 6.3E-20 T 14-10-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 TSH58p_23865 0d20f01934b9d7d8f73bc45af386b920 84 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 15 55 3.0E-11 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 TSH58p_23865 0d20f01934b9d7d8f73bc45af386b920 84 SUPERFAMILY SSF116842 9 74 1.31E-18 T 14-10-2018 TSH58p_23865 0d20f01934b9d7d8f73bc45af386b920 84 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 15 75 14.974 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 TSH58p_00615 2d8abc12565e6db004dd8892272b6335 132 SMART SM00448 1 109 3.3E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_00615 2d8abc12565e6db004dd8892272b6335 132 SUPERFAMILY SSF52172 1 114 9.53E-22 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_00615 2d8abc12565e6db004dd8892272b6335 132 Gene3D G3DSA:3.40.50.2300 1 119 2.8E-32 T 14-10-2018 TSH58p_00615 2d8abc12565e6db004dd8892272b6335 132 Pfam PF00072 Response regulator receiver domain 3 109 6.2E-12 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_17035 d40e04b00aa55aa53192dac78950d42b 139 SUPERFAMILY SSF110916 14 100 3.01E-13 T 14-10-2018 TSH58p_17035 d40e04b00aa55aa53192dac78950d42b 139 Gene3D G3DSA:3.30.160.20 1 137 6.9E-39 T 14-10-2018 TSH58p_17035 d40e04b00aa55aa53192dac78950d42b 139 Pfam PF00472 RF-1 domain 8 133 1.9E-22 T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TSH58p_17035 d40e04b00aa55aa53192dac78950d42b 139 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 21 37 - T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TSH58p_22280 92af270bd89859a605b27d74bb2f2a17 1038 Gene3D G3DSA:3.30.70.1430 562 659 1.3E-266 T 14-10-2018 TSH58p_22280 92af270bd89859a605b27d74bb2f2a17 1038 SUPERFAMILY SSF82693 43 128 3.66E-22 T 14-10-2018 TSH58p_22280 92af270bd89859a605b27d74bb2f2a17 1038 Gene3D G3DSA:3.30.70.1430 42 805 1.3E-266 T 14-10-2018 TSH58p_22280 92af270bd89859a605b27d74bb2f2a17 1038 Pfam PF00873 AcrB/AcrD/AcrF family 6 1015 3.7E-256 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_22280 92af270bd89859a605b27d74bb2f2a17 1038 Gene3D G3DSA:3.30.2090.10 180 271 1.3E-266 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_22280 92af270bd89859a605b27d74bb2f2a17 1038 Gene3D G3DSA:3.30.2090.10 711 797 1.3E-266 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_22280 92af270bd89859a605b27d74bb2f2a17 1038 SUPERFAMILY SSF82714 183 263 1.7E-13 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_22280 92af270bd89859a605b27d74bb2f2a17 1038 Gene3D G3DSA:1.20.1640.10 507 1013 1.3E-266 T 14-10-2018 TSH58p_22280 92af270bd89859a605b27d74bb2f2a17 1038 Gene3D G3DSA:1.20.1640.10 15 506 1.3E-266 T 14-10-2018 TSH58p_22280 92af270bd89859a605b27d74bb2f2a17 1038 SUPERFAMILY SSF82693 139 317 9.16E-19 T 14-10-2018 TSH58p_22280 92af270bd89859a605b27d74bb2f2a17 1038 SUPERFAMILY SSF82714 710 793 5.75E-13 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_22280 92af270bd89859a605b27d74bb2f2a17 1038 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1013 1.8E-229 T 14-10-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 TSH58p_22280 92af270bd89859a605b27d74bb2f2a17 1038 Gene3D G3DSA:3.30.70.1320 135 325 1.3E-266 T 14-10-2018 TSH58p_22280 92af270bd89859a605b27d74bb2f2a17 1038 PRINTS PR00702 Acriflavin resistance protein family signature 331 354 2.1E-36 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_22280 92af270bd89859a605b27d74bb2f2a17 1038 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 2.1E-36 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_22280 92af270bd89859a605b27d74bb2f2a17 1038 PRINTS PR00702 Acriflavin resistance protein family signature 358 379 2.1E-36 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_22280 92af270bd89859a605b27d74bb2f2a17 1038 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 2.1E-36 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_22280 92af270bd89859a605b27d74bb2f2a17 1038 PRINTS PR00702 Acriflavin resistance protein family signature 545 562 2.1E-36 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_22280 92af270bd89859a605b27d74bb2f2a17 1038 PRINTS PR00702 Acriflavin resistance protein family signature 386 410 2.1E-36 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_22280 92af270bd89859a605b27d74bb2f2a17 1038 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 2.1E-36 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_22280 92af270bd89859a605b27d74bb2f2a17 1038 SUPERFAMILY SSF82866 290 497 1.7E-38 T 14-10-2018 TSH58p_22280 92af270bd89859a605b27d74bb2f2a17 1038 SUPERFAMILY SSF82866 791 1019 8.63E-43 T 14-10-2018 TSH58p_22280 92af270bd89859a605b27d74bb2f2a17 1038 Gene3D G3DSA:3.30.70.1440 661 855 1.3E-266 T 14-10-2018 TSH58p_03935 12234578f5a93fcc05ad839bc06f417d 230 SUPERFAMILY SSF46894 150 213 2.04E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_03935 12234578f5a93fcc05ad839bc06f417d 230 SMART SM00421 151 208 1.2E-23 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_03935 12234578f5a93fcc05ad839bc06f417d 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 1.4E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_03935 12234578f5a93fcc05ad839bc06f417d 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 1.4E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_03935 12234578f5a93fcc05ad839bc06f417d 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 1.4E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_03935 12234578f5a93fcc05ad839bc06f417d 230 Pfam PF00072 Response regulator receiver domain 7 117 1.0E-12 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_03935 12234578f5a93fcc05ad839bc06f417d 230 Gene3D G3DSA:3.40.50.12740 4 213 1.1E-48 T 14-10-2018 TSH58p_03935 12234578f5a93fcc05ad839bc06f417d 230 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 208 1.0E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_03935 12234578f5a93fcc05ad839bc06f417d 230 SUPERFAMILY SSF52172 1 121 1.71E-19 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_03935 12234578f5a93fcc05ad839bc06f417d 230 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_03935 12234578f5a93fcc05ad839bc06f417d 230 SMART SM00448 4 117 8.7E-11 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_27585 9bb7166f0a2cc3c942899f011ec6a05b 288 Pfam PF01618 MotA/TolQ/ExbB proton channel family 141 235 3.2E-15 T 14-10-2018 IPR002898 MotA/TolQ/ExbB proton channel TSH58p_27585 9bb7166f0a2cc3c942899f011ec6a05b 288 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 207 224 - T 14-10-2018 IPR000540 Flagellar motor protein MotA, conserved site TSH58p_15815 540b5dcc0058eace82372ddd8bcfcc4d 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 4.0E-27 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_15815 540b5dcc0058eace82372ddd8bcfcc4d 225 Gene3D G3DSA:1.10.10.10 123 225 8.1E-35 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_15815 540b5dcc0058eace82372ddd8bcfcc4d 225 SUPERFAMILY SSF52172 1 180 2.41E-39 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_15815 540b5dcc0058eace82372ddd8bcfcc4d 225 Pfam PF00072 Response regulator receiver domain 3 113 5.1E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_15815 540b5dcc0058eace82372ddd8bcfcc4d 225 SMART SM00448 1 112 6.3E-38 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_15815 540b5dcc0058eace82372ddd8bcfcc4d 225 Gene3D G3DSA:3.40.50.2300 1 122 2.4E-38 T 14-10-2018 TSH58p_15815 540b5dcc0058eace82372ddd8bcfcc4d 225 SMART SM00862 146 221 1.2E-27 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_11555 a0b887ef2fa918b2e32ad4f1cedfc45a 385 SUPERFAMILY SSF53850 48 382 3.8E-61 T 14-10-2018 TSH58p_11555 a0b887ef2fa918b2e32ad4f1cedfc45a 385 Pfam PF13416 Bacterial extracellular solute-binding protein 62 338 8.9E-27 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSH58p_11555 a0b887ef2fa918b2e32ad4f1cedfc45a 385 Gene3D G3DSA:3.40.190.10 51 343 3.1E-65 T 14-10-2018 TSH58p_11555 a0b887ef2fa918b2e32ad4f1cedfc45a 385 Gene3D G3DSA:3.40.190.10 156 292 3.1E-65 T 14-10-2018 TSH58p_11555 a0b887ef2fa918b2e32ad4f1cedfc45a 385 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 285 304 8.8E-23 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSH58p_11555 a0b887ef2fa918b2e32ad4f1cedfc45a 385 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 52 68 8.8E-23 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSH58p_11555 a0b887ef2fa918b2e32ad4f1cedfc45a 385 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 96 110 8.8E-23 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSH58p_11555 a0b887ef2fa918b2e32ad4f1cedfc45a 385 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 147 163 8.8E-23 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSH58p_11555 a0b887ef2fa918b2e32ad4f1cedfc45a 385 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 174 188 8.8E-23 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSH58p_11555 a0b887ef2fa918b2e32ad4f1cedfc45a 385 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 68 89 8.8E-23 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSH58p_13880 8564a03f36da22576f0b0c6373a52a1f 286 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 129 277 3.8E-8 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_13880 8564a03f36da22576f0b0c6373a52a1f 286 Gene3D G3DSA:3.40.190.10 26 97 2.1E-11 T 14-10-2018 TSH58p_13880 8564a03f36da22576f0b0c6373a52a1f 286 SMART SM00062 40 280 0.0031 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_13880 8564a03f36da22576f0b0c6373a52a1f 286 Gene3D G3DSA:3.40.190.10 236 276 2.8E-9 T 14-10-2018 TSH58p_13880 8564a03f36da22576f0b0c6373a52a1f 286 Gene3D G3DSA:3.40.190.10 184 235 2.8E-9 T 14-10-2018 TSH58p_13880 8564a03f36da22576f0b0c6373a52a1f 286 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 41 86 1.9E-8 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_13880 8564a03f36da22576f0b0c6373a52a1f 286 SUPERFAMILY SSF53850 32 275 2.39E-25 T 14-10-2018 TSH58p_14615 a49bf222d8b57ac12f76138b4e46466b 284 Pfam PF01545 Cation efflux family 2 192 6.6E-47 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TSH58p_14615 a49bf222d8b57ac12f76138b4e46466b 284 SUPERFAMILY SSF161111 2 193 3.14E-56 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TSH58p_14615 a49bf222d8b57ac12f76138b4e46466b 284 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 2 272 3.3E-84 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TSH58p_14615 a49bf222d8b57ac12f76138b4e46466b 284 Gene3D G3DSA:1.20.1510.10 1 192 1.9E-44 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TSH58p_14615 a49bf222d8b57ac12f76138b4e46466b 284 SUPERFAMILY SSF160240 200 270 8.5E-8 T 14-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 TSH58p_29715 7635c435b766d882179f597365902696 346 Pfam PF05128 Domain of unknown function (DUF697) 186 341 1.3E-46 T 14-10-2018 IPR021147 Protein of unknown function DUF697 TSH58p_29715 7635c435b766d882179f597365902696 346 TIGRFAM TIGR01620 hyp_HI0043: TIGR01620 family protein 56 340 2.2E-70 T 14-10-2018 IPR006507 Uncharacterised protein family UPF0283 TSH58p_20425 9fa58c8f6c61a9763ae3a4747f664a2f 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 6.9E-22 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_20425 9fa58c8f6c61a9763ae3a4747f664a2f 311 Gene3D G3DSA:3.40.190.290 90 281 5.1E-23 T 14-10-2018 TSH58p_20425 9fa58c8f6c61a9763ae3a4747f664a2f 311 Pfam PF03466 LysR substrate binding domain 86 272 5.8E-29 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_20425 9fa58c8f6c61a9763ae3a4747f664a2f 311 SUPERFAMILY SSF46785 1 84 7.07E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_20425 9fa58c8f6c61a9763ae3a4747f664a2f 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.8E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_20425 9fa58c8f6c61a9763ae3a4747f664a2f 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.8E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_20425 9fa58c8f6c61a9763ae3a4747f664a2f 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.8E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_20425 9fa58c8f6c61a9763ae3a4747f664a2f 311 SUPERFAMILY SSF53850 85 272 6.24E-26 T 14-10-2018 TSH58p_20425 9fa58c8f6c61a9763ae3a4747f664a2f 311 Gene3D G3DSA:1.10.10.10 1 89 2.7E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_04955 470e3ad892ab9dab94c782a38b8659bc 136 SUPERFAMILY SSF47188 1 130 2.09E-29 T 14-10-2018 IPR035938 Hemerythrin-like superfamily TSH58p_04955 470e3ad892ab9dab94c782a38b8659bc 136 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 5 130 1.3E-31 T 14-10-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 TSH58p_04955 470e3ad892ab9dab94c782a38b8659bc 136 Pfam PF01814 Hemerythrin HHE cation binding domain 17 129 4.1E-11 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 TSH58p_04955 470e3ad892ab9dab94c782a38b8659bc 136 ProSitePatterns PS00550 Hemerythrin family signature. 59 82 - T 14-10-2018 IPR016131 Haemerythrin, iron-binding site GO:0046872 TSH58p_04955 470e3ad892ab9dab94c782a38b8659bc 136 Gene3D G3DSA:1.20.120.50 2 134 1.8E-34 T 14-10-2018 IPR035938 Hemerythrin-like superfamily TSH58p_26825 26db84621198f2bfaef4e82bef2368d2 256 Pfam PF00005 ABC transporter 24 163 5.4E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_26825 26db84621198f2bfaef4e82bef2368d2 256 SMART SM00382 33 214 3.5E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_26825 26db84621198f2bfaef4e82bef2368d2 256 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_26825 26db84621198f2bfaef4e82bef2368d2 256 Gene3D G3DSA:3.40.50.300 3 246 5.7E-66 T 14-10-2018 TSH58p_26825 26db84621198f2bfaef4e82bef2368d2 256 SUPERFAMILY SSF52540 4 232 1.56E-71 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_08740 55d81d77e70c47161c5b4ef9540ed34e 234 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 219 4.6E-43 T 14-10-2018 TSH58p_08740 55d81d77e70c47161c5b4ef9540ed34e 234 SMART SM01211 1 233 1.1E-122 T 14-10-2018 TSH58p_08740 55d81d77e70c47161c5b4ef9540ed34e 234 SUPERFAMILY SSF52317 1 232 1.21E-74 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_08740 55d81d77e70c47161c5b4ef9540ed34e 234 Gene3D G3DSA:3.40.50.880 1 234 2.0E-67 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_08740 55d81d77e70c47161c5b4ef9540ed34e 234 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 232 1.5E-94 T 14-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSH58p_08740 55d81d77e70c47161c5b4ef9540ed34e 234 PIRSF PIRSF001586 1 234 1.3E-86 T 14-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSH58p_08740 55d81d77e70c47161c5b4ef9540ed34e 234 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 231 43.242 T 14-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSH58p_07820 7ed1f7229607f36bba945e6ea5a2c3fc 324 Pfam PF02685 Glucokinase 14 322 7.8E-108 T 14-10-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0005536|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 TSH58p_07820 7ed1f7229607f36bba945e6ea5a2c3fc 324 SUPERFAMILY SSF53067 12 321 1.99E-57 T 14-10-2018 TSH58p_07820 7ed1f7229607f36bba945e6ea5a2c3fc 324 Gene3D G3DSA:3.40.367.20 108 307 2.0E-103 T 14-10-2018 TSH58p_07820 7ed1f7229607f36bba945e6ea5a2c3fc 324 Hamap MF_00524 Glucokinase [glk]. 12 324 34.13 T 14-10-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0005536|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 TSH58p_07820 7ed1f7229607f36bba945e6ea5a2c3fc 324 TIGRFAM TIGR00749 glk: glucokinase 14 316 5.7E-92 T 14-10-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0005536|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 TSH58p_07820 7ed1f7229607f36bba945e6ea5a2c3fc 324 Gene3D G3DSA:3.30.420.40 14 318 2.0E-103 T 14-10-2018 TSH58p_26325 fb35b2abae6d1202b90964e12ac60324 286 TIGRFAM TIGR03818 MotA1: flagellar motor stator protein MotA 1 280 1.8E-110 T 14-10-2018 IPR022522 Flagellar motor stator, MotA TSH58p_26325 fb35b2abae6d1202b90964e12ac60324 286 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 205 222 - T 14-10-2018 IPR000540 Flagellar motor protein MotA, conserved site TSH58p_26325 fb35b2abae6d1202b90964e12ac60324 286 Pfam PF01618 MotA/TolQ/ExbB proton channel family 138 238 4.7E-13 T 14-10-2018 IPR002898 MotA/TolQ/ExbB proton channel TSH58p_23485 4671d3a1b59fa204e65f8241a2e5468d 191 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 56 88 - T 14-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_23485 4671d3a1b59fa204e65f8241a2e5468d 191 Pfam PF04542 Sigma-70 region 2 34 102 8.1E-20 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_23485 4671d3a1b59fa204e65f8241a2e5468d 191 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 30 186 1.1E-28 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TSH58p_23485 4671d3a1b59fa204e65f8241a2e5468d 191 SUPERFAMILY SSF88946 13 117 3.73E-26 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_23485 4671d3a1b59fa204e65f8241a2e5468d 191 Gene3D G3DSA:1.10.1740.10 14 96 1.3E-28 T 14-10-2018 TSH58p_23485 4671d3a1b59fa204e65f8241a2e5468d 191 Gene3D G3DSA:1.10.10.10 97 188 1.0E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_23485 4671d3a1b59fa204e65f8241a2e5468d 191 Pfam PF04545 Sigma-70, region 4 137 185 1.4E-11 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 TSH58p_23485 4671d3a1b59fa204e65f8241a2e5468d 191 SUPERFAMILY SSF88659 110 187 1.44E-13 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSH58p_15710 ad833f30fd1b637863b064f010d5fca1 644 Pfam PF01807 CHC2 zinc finger 5 97 2.1E-32 T 14-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 TSH58p_15710 ad833f30fd1b637863b064f010d5fca1 644 TIGRFAM TIGR01391 dnaG: DNA primase 4 418 3.1E-130 T 14-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 TSH58p_15710 ad833f30fd1b637863b064f010d5fca1 644 Gene3D G3DSA:3.90.980.10 106 237 7.3E-38 T 14-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily TSH58p_15710 ad833f30fd1b637863b064f010d5fca1 644 PIRSF PIRSF002811 453 632 0.3 T 14-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 TSH58p_15710 ad833f30fd1b637863b064f010d5fca1 644 PIRSF PIRSF002811 1 431 3.0E-129 T 14-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 TSH58p_15710 ad833f30fd1b637863b064f010d5fca1 644 SUPERFAMILY SSF57783 1 97 9.01E-35 T 14-10-2018 TSH58p_15710 ad833f30fd1b637863b064f010d5fca1 644 Pfam PF13662 Toprim domain 258 327 1.0E-13 T 14-10-2018 IPR006171 TOPRIM domain TSH58p_15710 ad833f30fd1b637863b064f010d5fca1 644 SMART SM00400 34 88 3.3E-29 T 14-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 TSH58p_15710 ad833f30fd1b637863b064f010d5fca1 644 SUPERFAMILY SSF56731 112 421 9.42E-97 T 14-10-2018 TSH58p_15710 ad833f30fd1b637863b064f010d5fca1 644 SMART SM00493 256 331 3.0E-14 T 14-10-2018 IPR006171 TOPRIM domain TSH58p_15710 ad833f30fd1b637863b064f010d5fca1 644 Gene3D G3DSA:3.90.580.10 1 100 1.0E-35 T 14-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 TSH58p_15710 ad833f30fd1b637863b064f010d5fca1 644 Gene3D G3DSA:3.40.1360.10 238 368 1.1E-38 T 14-10-2018 TSH58p_15710 ad833f30fd1b637863b064f010d5fca1 644 Hamap MF_00974 DNA primase [dnaG]. 2 630 25.327 T 14-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 TSH58p_15710 ad833f30fd1b637863b064f010d5fca1 644 Pfam PF08275 DNA primase catalytic core, N-terminal domain 122 248 1.1E-36 T 14-10-2018 IPR013264 DNA primase, catalytic core, N-terminal TSH58p_02750 ce6584358d14fd04a9f64d7e58d7a44e 321 Gene3D G3DSA:3.40.50.720 1 194 1.3E-48 T 14-10-2018 TSH58p_02750 ce6584358d14fd04a9f64d7e58d7a44e 321 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 173 2.2E-19 T 14-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain TSH58p_02750 ce6584358d14fd04a9f64d7e58d7a44e 321 Gene3D G3DSA:1.10.1040.10 197 321 2.7E-18 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSH58p_02750 ce6584358d14fd04a9f64d7e58d7a44e 321 SUPERFAMILY SSF48179 197 317 2.55E-12 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_02750 ce6584358d14fd04a9f64d7e58d7a44e 321 SUPERFAMILY SSF51735 1 133 3.57E-15 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_02750 ce6584358d14fd04a9f64d7e58d7a44e 321 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 197 317 5.1E-12 T 14-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain TSH58p_11060 affaf3fbd8763671353e7a33a225d68f 279 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 8 274 3.4E-69 T 14-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 TSH58p_11060 affaf3fbd8763671353e7a33a225d68f 279 SUPERFAMILY SSF51735 108 274 6.51E-41 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_11060 affaf3fbd8763671353e7a33a225d68f 279 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 129 197 1.4E-8 T 14-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase TSH58p_11060 affaf3fbd8763671353e7a33a225d68f 279 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 7 278 33.194 T 14-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 TSH58p_11060 affaf3fbd8763671353e7a33a225d68f 279 SUPERFAMILY SSF53223 1 107 1.5E-32 T 14-10-2018 TSH58p_11060 affaf3fbd8763671353e7a33a225d68f 279 Gene3D G3DSA:3.40.50.720 107 245 1.3E-80 T 14-10-2018 TSH58p_11060 affaf3fbd8763671353e7a33a225d68f 279 Gene3D G3DSA:3.40.50.10860 11 266 1.3E-80 T 14-10-2018 TSH58p_11060 affaf3fbd8763671353e7a33a225d68f 279 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 12 94 2.3E-28 T 14-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 TSH58p_11110 aea247a4f3dc34906babad6b3642a435 401 PIRSF PIRSF019422 1 401 1.0E-140 T 14-10-2018 IPR026044 Membrane-bound lytic murein transglycosylase A TSH58p_11110 aea247a4f3dc34906babad6b3642a435 401 Gene3D G3DSA:2.40.40.10 48 395 4.9E-139 T 14-10-2018 IPR036908 RlpA-like domain superfamily TSH58p_11110 aea247a4f3dc34906babad6b3642a435 401 SMART SM00925 142 299 4.3E-88 T 14-10-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 TSH58p_11110 aea247a4f3dc34906babad6b3642a435 401 Gene3D G3DSA:2.40.240.50 141 304 4.9E-139 T 14-10-2018 TSH58p_11110 aea247a4f3dc34906babad6b3642a435 401 Pfam PF06725 3D domain 318 392 1.2E-20 T 14-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 TSH58p_11110 aea247a4f3dc34906babad6b3642a435 401 SUPERFAMILY SSF50685 36 399 1.36E-129 T 14-10-2018 IPR036908 RlpA-like domain superfamily TSH58p_11110 aea247a4f3dc34906babad6b3642a435 401 Pfam PF03562 MltA specific insert domain 54 299 3.9E-84 T 14-10-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 TSH58p_02840 d2c0e85cde60b8b46779bbda781be27b 359 Gene3D G3DSA:3.40.50.720 5 278 5.8E-62 T 14-10-2018 TSH58p_02840 d2c0e85cde60b8b46779bbda781be27b 359 SUPERFAMILY SSF51735 3 347 5.39E-59 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_02840 d2c0e85cde60b8b46779bbda781be27b 359 Gene3D G3DSA:3.90.25.10 214 345 5.8E-62 T 14-10-2018 TSH58p_02840 d2c0e85cde60b8b46779bbda781be27b 359 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 278 2.3E-35 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TSH58p_25770 6218cd5e5b9ed0ee2640d7b07d33f4da 261 Gene3D G3DSA:3.40.50.300 10 236 7.3E-68 T 14-10-2018 TSH58p_25770 6218cd5e5b9ed0ee2640d7b07d33f4da 261 SMART SM00382 34 214 8.7E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_25770 6218cd5e5b9ed0ee2640d7b07d33f4da 261 Pfam PF00005 ABC transporter 25 165 5.7E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_25770 6218cd5e5b9ed0ee2640d7b07d33f4da 261 SUPERFAMILY SSF52540 20 224 6.53E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_25770 6218cd5e5b9ed0ee2640d7b07d33f4da 261 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_09185 e8f747283633871f4b5dedb9a1e8eaae 654 SMART SM00863 176 226 3.8E-24 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TSH58p_09185 e8f747283633871f4b5dedb9a1e8eaae 654 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 325 538 1.8E-43 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_09185 e8f747283633871f4b5dedb9a1e8eaae 654 PRINTS PR01047 Threonyl-tRNA synthetase signature 338 366 1.3E-52 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TSH58p_09185 e8f747283633871f4b5dedb9a1e8eaae 654 PRINTS PR01047 Threonyl-tRNA synthetase signature 473 501 1.3E-52 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TSH58p_09185 e8f747283633871f4b5dedb9a1e8eaae 654 PRINTS PR01047 Threonyl-tRNA synthetase signature 371 394 1.3E-52 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TSH58p_09185 e8f747283633871f4b5dedb9a1e8eaae 654 PRINTS PR01047 Threonyl-tRNA synthetase signature 543 555 1.3E-52 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TSH58p_09185 e8f747283633871f4b5dedb9a1e8eaae 654 PRINTS PR01047 Threonyl-tRNA synthetase signature 516 529 1.3E-52 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TSH58p_09185 e8f747283633871f4b5dedb9a1e8eaae 654 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 73 643 33.646 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TSH58p_09185 e8f747283633871f4b5dedb9a1e8eaae 654 SUPERFAMILY SSF52954 536 640 9.82E-29 T 14-10-2018 TSH58p_09185 e8f747283633871f4b5dedb9a1e8eaae 654 Gene3D G3DSA:3.30.930.10 230 540 1.7E-121 T 14-10-2018 TSH58p_09185 e8f747283633871f4b5dedb9a1e8eaae 654 SUPERFAMILY SSF55681 250 535 4.98E-98 T 14-10-2018 TSH58p_09185 e8f747283633871f4b5dedb9a1e8eaae 654 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 176 226 2.2E-12 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TSH58p_09185 e8f747283633871f4b5dedb9a1e8eaae 654 SUPERFAMILY SSF81271 9 68 4.58E-15 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 TSH58p_09185 e8f747283633871f4b5dedb9a1e8eaae 654 Gene3D G3DSA:3.10.20.30 6 69 2.6E-22 T 14-10-2018 IPR012675 Beta-grasp domain superfamily TSH58p_09185 e8f747283633871f4b5dedb9a1e8eaae 654 Gene3D G3DSA:3.30.54.20 137 193 1.0E-62 T 14-10-2018 TSH58p_09185 e8f747283633871f4b5dedb9a1e8eaae 654 Pfam PF02824 TGS domain 9 68 6.8E-9 T 14-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 TSH58p_09185 e8f747283633871f4b5dedb9a1e8eaae 654 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 79 640 3.4E-209 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TSH58p_09185 e8f747283633871f4b5dedb9a1e8eaae 654 Gene3D G3DSA:3.40.50.800 541 647 1.0E-26 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily TSH58p_09185 e8f747283633871f4b5dedb9a1e8eaae 654 Pfam PF03129 Anticodon binding domain 550 639 2.1E-17 T 14-10-2018 IPR004154 Anticodon-binding TSH58p_09185 e8f747283633871f4b5dedb9a1e8eaae 654 SUPERFAMILY SSF55186 71 248 9.42E-64 T 14-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 TSH58p_09185 e8f747283633871f4b5dedb9a1e8eaae 654 Gene3D G3DSA:3.30.980.10 76 229 1.0E-62 T 14-10-2018 TSH58p_09310 c571d99cd4c9feffe641484b51fbf381 282 ProSitePatterns PS00770 Aminotransferases class-IV signature. 184 213 - T 14-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 TSH58p_09310 c571d99cd4c9feffe641484b51fbf381 282 SUPERFAMILY SSF56752 10 280 2.09E-70 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 TSH58p_09310 c571d99cd4c9feffe641484b51fbf381 282 Gene3D G3DSA:3.20.10.10 131 280 2.2E-41 T 14-10-2018 TSH58p_09310 c571d99cd4c9feffe641484b51fbf381 282 Pfam PF01063 Amino-transferase class IV 37 258 1.8E-39 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 TSH58p_09310 c571d99cd4c9feffe641484b51fbf381 282 Gene3D G3DSA:3.30.470.10 2 128 1.0E-31 T 14-10-2018 TSH58p_26465 5c75e7bcc486051973d093262bb0dc7f 144 SUPERFAMILY SSF50692 2 118 1.12E-41 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TSH58p_26465 5c75e7bcc486051973d093262bb0dc7f 144 Gene3D G3DSA:2.40.40.20 1 122 8.0E-42 T 14-10-2018 TSH58p_26465 5c75e7bcc486051973d093262bb0dc7f 144 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 126 51.906 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 TSH58p_26465 5c75e7bcc486051973d093262bb0dc7f 144 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 4 91 7.0E-35 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 TSH58p_26465 5c75e7bcc486051973d093262bb0dc7f 144 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 3 117 8.3E-35 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 TSH58p_26465 5c75e7bcc486051973d093262bb0dc7f 144 Pfam PF02261 Aspartate decarboxylase 2 113 6.3E-41 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 TSH58p_26465 5c75e7bcc486051973d093262bb0dc7f 144 PIRSF PIRSF006246 1 127 2.3E-48 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 TSH58p_30715 44b0930c805b4dd3a6ede4f51cf96e22 853 Gene3D G3DSA:3.30.300.30 404 502 5.9E-7 T 14-10-2018 TSH58p_30715 44b0930c805b4dd3a6ede4f51cf96e22 853 Gene3D G3DSA:3.40.50.12780 2 399 1.7E-62 T 14-10-2018 TSH58p_30715 44b0930c805b4dd3a6ede4f51cf96e22 853 Pfam PF00892 EamA-like transporter family 535 670 5.7E-19 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_30715 44b0930c805b4dd3a6ede4f51cf96e22 853 SUPERFAMILY SSF56801 5 497 3.92E-73 T 14-10-2018 TSH58p_30715 44b0930c805b4dd3a6ede4f51cf96e22 853 ProSitePatterns PS00455 Putative AMP-binding domain signature. 162 173 - T 14-10-2018 IPR020845 AMP-binding, conserved site TSH58p_30715 44b0930c805b4dd3a6ede4f51cf96e22 853 SUPERFAMILY SSF103481 570 672 3.92E-7 T 14-10-2018 TSH58p_30715 44b0930c805b4dd3a6ede4f51cf96e22 853 Pfam PF00501 AMP-binding enzyme 8 402 7.5E-53 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_03790 75b25fe11afb19cb57c98a0a9354e581 279 Gene3D G3DSA:3.40.1010.10 20 136 1.3E-39 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 TSH58p_03790 75b25fe11afb19cb57c98a0a9354e581 279 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 101 134 - T 14-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TSH58p_03790 75b25fe11afb19cb57c98a0a9354e581 279 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 21 258 1.5E-82 T 14-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TSH58p_03790 75b25fe11afb19cb57c98a0a9354e581 279 Gene3D G3DSA:3.30.950.10 137 276 6.8E-41 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 TSH58p_03790 75b25fe11afb19cb57c98a0a9354e581 279 SUPERFAMILY SSF53790 19 259 6.94E-70 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 TSH58p_03790 75b25fe11afb19cb57c98a0a9354e581 279 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 23 233 9.0E-43 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 TSH58p_01565 c2aeee16de7b8d4bed0ab6be0d4a491b 199 SUPERFAMILY SSF54211 2 120 2.58E-38 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSH58p_01565 c2aeee16de7b8d4bed0ab6be0d4a491b 199 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 70 99 - T 14-10-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site TSH58p_01565 c2aeee16de7b8d4bed0ab6be0d4a491b 199 Pfam PF01205 Uncharacterized protein family UPF0029 15 115 2.0E-27 T 14-10-2018 IPR001498 Impact, N-terminal TSH58p_01565 c2aeee16de7b8d4bed0ab6be0d4a491b 199 Pfam PF09186 Domain of unknown function (DUF1949) 131 188 7.5E-6 T 14-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal TSH58p_01565 c2aeee16de7b8d4bed0ab6be0d4a491b 199 Gene3D G3DSA:3.30.230.30 1 124 1.9E-46 T 14-10-2018 IPR036956 Impact, N-terminal domain superfamily TSH58p_01565 c2aeee16de7b8d4bed0ab6be0d4a491b 199 SUPERFAMILY SSF54980 129 192 1.15E-6 T 14-10-2018 IPR035647 EF-G domain III/V-like TSH58p_01565 c2aeee16de7b8d4bed0ab6be0d4a491b 199 Gene3D G3DSA:3.30.70.240 127 192 6.8E-6 T 14-10-2018 TSH58p_24660 6c1a05e5c79d7df0276f1f6dc7c00586 216 Gene3D G3DSA:1.10.357.10 5 202 8.4E-45 T 14-10-2018 TSH58p_24660 6c1a05e5c79d7df0276f1f6dc7c00586 216 SUPERFAMILY SSF48498 85 199 1.74E-19 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TSH58p_24660 6c1a05e5c79d7df0276f1f6dc7c00586 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 60 8.3E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_24660 6c1a05e5c79d7df0276f1f6dc7c00586 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 1.3E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_24660 6c1a05e5c79d7df0276f1f6dc7c00586 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 1.3E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_24660 6c1a05e5c79d7df0276f1f6dc7c00586 216 SUPERFAMILY SSF46689 7 81 1.85E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_24660 6c1a05e5c79d7df0276f1f6dc7c00586 216 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 60 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site TSH58p_29980 735984e2dec8932224805949e17ea6d2 191 Pfam PF03852 DNA mismatch endonuclease Vsr 19 83 2.1E-27 T 14-10-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 TSH58p_29980 735984e2dec8932224805949e17ea6d2 191 Gene3D G3DSA:3.40.960.10 33 157 1.8E-46 T 14-10-2018 TSH58p_29980 735984e2dec8932224805949e17ea6d2 191 SUPERFAMILY SSF52980 20 152 4.88E-46 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TSH58p_29980 735984e2dec8932224805949e17ea6d2 191 TIGRFAM TIGR00632 vsr: DNA mismatch endonuclease Vsr 18 131 1.9E-41 T 14-10-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 TSH58p_30140 735984e2dec8932224805949e17ea6d2 191 Pfam PF03852 DNA mismatch endonuclease Vsr 19 83 2.1E-27 T 14-10-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 TSH58p_30140 735984e2dec8932224805949e17ea6d2 191 Gene3D G3DSA:3.40.960.10 33 157 1.8E-46 T 14-10-2018 TSH58p_30140 735984e2dec8932224805949e17ea6d2 191 SUPERFAMILY SSF52980 20 152 4.88E-46 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TSH58p_30140 735984e2dec8932224805949e17ea6d2 191 TIGRFAM TIGR00632 vsr: DNA mismatch endonuclease Vsr 18 131 1.9E-41 T 14-10-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 TSH58p_15510 0bc9c550c178c953dd6b86649a84a975 358 SUPERFAMILY SSF160544 245 352 9.81E-43 T 14-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal TSH58p_15510 0bc9c550c178c953dd6b86649a84a975 358 Gene3D G3DSA:3.40.1690.10 219 357 1.2E-59 T 14-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal TSH58p_15510 0bc9c550c178c953dd6b86649a84a975 358 Pfam PF01312 FlhB HrpN YscU SpaS Family 9 348 4.6E-120 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 TSH58p_15510 0bc9c550c178c953dd6b86649a84a975 358 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 229 246 1.5E-42 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 TSH58p_15510 0bc9c550c178c953dd6b86649a84a975 358 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 273 288 1.5E-42 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 TSH58p_15510 0bc9c550c178c953dd6b86649a84a975 358 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 303 324 1.5E-42 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 TSH58p_15510 0bc9c550c178c953dd6b86649a84a975 358 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 11 33 1.5E-42 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 TSH58p_15510 0bc9c550c178c953dd6b86649a84a975 358 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 209 227 1.5E-42 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 TSH58p_15510 0bc9c550c178c953dd6b86649a84a975 358 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 9 353 1.5E-118 T 14-10-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 TSH58p_20005 0fc1497958f08b16129d32b59fae4413 519 Pfam PF12833 Helix-turn-helix domain 431 511 2.2E-24 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TSH58p_20005 0fc1497958f08b16129d32b59fae4413 519 Pfam PF14532 Sigma-54 interaction domain 115 275 7.0E-20 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 TSH58p_20005 0fc1497958f08b16129d32b59fae4413 519 Gene3D G3DSA:1.10.8.60 275 348 3.7E-9 T 14-10-2018 TSH58p_20005 0fc1497958f08b16129d32b59fae4413 519 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 462 505 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 TSH58p_20005 0fc1497958f08b16129d32b59fae4413 519 Gene3D G3DSA:1.10.10.60 410 516 1.2E-27 T 14-10-2018 TSH58p_20005 0fc1497958f08b16129d32b59fae4413 519 SMART SM00342 425 509 8.2E-30 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TSH58p_20005 0fc1497958f08b16129d32b59fae4413 519 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 478 493 7.4E-7 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TSH58p_20005 0fc1497958f08b16129d32b59fae4413 519 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 493 509 7.4E-7 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TSH58p_20005 0fc1497958f08b16129d32b59fae4413 519 SUPERFAMILY SSF46689 461 512 5.38E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_20005 0fc1497958f08b16129d32b59fae4413 519 Gene3D G3DSA:3.40.50.300 113 274 4.9E-30 T 14-10-2018 TSH58p_20005 0fc1497958f08b16129d32b59fae4413 519 SUPERFAMILY SSF52540 114 343 4.59E-25 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_06515 96e4492827876a96f195ac2494a328eb 168 Gene3D G3DSA:3.30.70.260 5 85 5.1E-32 T 14-10-2018 TSH58p_06515 96e4492827876a96f195ac2494a328eb 168 SUPERFAMILY SSF55021 7 82 1.06E-18 T 14-10-2018 TSH58p_06515 96e4492827876a96f195ac2494a328eb 168 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 7 82 8.0E-28 T 14-10-2018 TSH58p_06515 96e4492827876a96f195ac2494a328eb 168 Pfam PF13710 ACT domain 17 79 7.0E-13 T 14-10-2018 TSH58p_06515 96e4492827876a96f195ac2494a328eb 168 Gene3D G3DSA:3.30.70.1150 90 167 2.5E-23 T 14-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal TSH58p_06515 96e4492827876a96f195ac2494a328eb 168 Pfam PF10369 Small subunit of acetolactate synthase 91 164 1.6E-23 T 14-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 TSH58p_06515 96e4492827876a96f195ac2494a328eb 168 SUPERFAMILY SSF55021 86 165 5.04E-23 T 14-10-2018 TSH58p_06515 96e4492827876a96f195ac2494a328eb 168 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 7 164 7.5E-51 T 14-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 TSH58p_20505 6c036460efd94a468b0ce551cdfe90ce 585 Gene3D G3DSA:3.40.50.970 368 581 5.9E-57 T 14-10-2018 TSH58p_20505 6c036460efd94a468b0ce551cdfe90ce 585 Gene3D G3DSA:3.40.50.970 14 206 7.8E-60 T 14-10-2018 TSH58p_20505 6c036460efd94a468b0ce551cdfe90ce 585 SUPERFAMILY SSF52518 23 192 1.23E-42 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_20505 6c036460efd94a468b0ce551cdfe90ce 585 SUPERFAMILY SSF52467 207 373 4.7E-40 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TSH58p_20505 6c036460efd94a468b0ce551cdfe90ce 585 Gene3D G3DSA:3.40.50.1220 207 366 6.1E-43 T 14-10-2018 TSH58p_20505 6c036460efd94a468b0ce551cdfe90ce 585 TIGRFAM TIGR03254 oxalate_oxc: oxalyl-CoA decarboxylase 21 575 4.4E-301 T 14-10-2018 IPR017660 Oxalyl-CoA decarboxylase GO:0008949|GO:0030976|GO:0033611|GO:0046872 KEGG: 00630+4.1.1.8|MetaCyc: PWY-6695|MetaCyc: PWY-6696|MetaCyc: PWY-7985 TSH58p_20505 6c036460efd94a468b0ce551cdfe90ce 585 SUPERFAMILY SSF52518 386 564 1.27E-39 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_20505 6c036460efd94a468b0ce551cdfe90ce 585 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 215 346 1.0E-32 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 TSH58p_20505 6c036460efd94a468b0ce551cdfe90ce 585 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 412 556 4.9E-24 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TSH58p_20505 6c036460efd94a468b0ce551cdfe90ce 585 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 24 191 3.8E-45 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 TSH58p_02745 49ef915ff3e1d9487a247b6d9ed4258f 409 Gene3D G3DSA:3.30.70.360 212 326 9.2E-154 T 14-10-2018 TSH58p_02745 49ef915ff3e1d9487a247b6d9ed4258f 409 SUPERFAMILY SSF55031 212 326 1.05E-27 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TSH58p_02745 49ef915ff3e1d9487a247b6d9ed4258f 409 Pfam PF01546 Peptidase family M20/M25/M40 80 405 2.2E-35 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 TSH58p_02745 49ef915ff3e1d9487a247b6d9ed4258f 409 Gene3D G3DSA:3.40.630.10 18 401 9.2E-154 T 14-10-2018 TSH58p_02745 49ef915ff3e1d9487a247b6d9ed4258f 409 SUPERFAMILY SSF53187 4 406 1.23E-95 T 14-10-2018 TSH58p_02745 49ef915ff3e1d9487a247b6d9ed4258f 409 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 9 405 1.7E-127 T 14-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 TSH58p_02745 49ef915ff3e1d9487a247b6d9ed4258f 409 PIRSF PIRSF001235 3 409 1.7E-135 T 14-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 TSH58p_09985 b629b50bd26ad7a1d2ef5380ec6d4e42 469 PIRSF PIRSF031802 1 464 5.8E-136 T 14-10-2018 IPR016982 Uncharacterised conserved protein UCP031802 TSH58p_09985 b629b50bd26ad7a1d2ef5380ec6d4e42 469 SUPERFAMILY SSF48452 242 381 1.37E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_09985 b629b50bd26ad7a1d2ef5380ec6d4e42 469 Gene3D G3DSA:1.25.40.10 77 310 4.1E-17 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_09985 b629b50bd26ad7a1d2ef5380ec6d4e42 469 SUPERFAMILY SSF48452 88 294 2.53E-13 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_09985 b629b50bd26ad7a1d2ef5380ec6d4e42 469 Pfam PF07219 HemY protein N-terminus 26 132 7.0E-29 T 14-10-2018 IPR010817 HemY, N-terminal TSH58p_09985 b629b50bd26ad7a1d2ef5380ec6d4e42 469 Gene3D G3DSA:1.25.40.10 311 400 2.5E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_07640 f898a99abeb67380ac09cd14e36b6543 479 SUPERFAMILY SSF53807 26 478 1.78E-167 T 14-10-2018 TSH58p_07640 f898a99abeb67380ac09cd14e36b6543 479 ProSitePatterns PS00090 Nitrogenases component 1 alpha and beta subunits signature 2. 152 166 - T 14-10-2018 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 TSH58p_07640 f898a99abeb67380ac09cd14e36b6543 479 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 62 466 9.9E-113 T 14-10-2018 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 TSH58p_07640 f898a99abeb67380ac09cd14e36b6543 479 Gene3D G3DSA:3.40.50.1980 29 474 1.9E-221 T 14-10-2018 TSH58p_07640 f898a99abeb67380ac09cd14e36b6543 479 TIGRFAM TIGR01282 nifD: nitrogenase molybdenum-iron protein alpha chain 14 479 1.3E-268 T 14-10-2018 IPR005972 Nitrogenase molybdenum-iron protein alpha chain GO:0009399|GO:0016163|GO:0016612|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 TSH58p_07640 f898a99abeb67380ac09cd14e36b6543 479 Gene3D G3DSA:3.40.50.1980 206 345 1.9E-221 T 14-10-2018 TSH58p_07640 f898a99abeb67380ac09cd14e36b6543 479 ProSitePatterns PS00699 Nitrogenases component 1 alpha and beta subunits signature 1. 81 88 - T 14-10-2018 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 TSH58p_07640 f898a99abeb67380ac09cd14e36b6543 479 Gene3D G3DSA:3.40.50.1980 63 205 1.9E-221 T 14-10-2018 TSH58p_07640 f898a99abeb67380ac09cd14e36b6543 479 TIGRFAM TIGR01862 N2-ase-Ialpha: nitrogenase component I, alpha chain 30 472 2.1E-190 T 14-10-2018 IPR010143 Nitrogenase component 1, alpha chain GO:0009399|GO:0016163|GO:0051536|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 TSH58p_05440 a25891902542ecea08bb81b805dc3a76 410 TIGRFAM TIGR01747 diampropi_NH3ly: diaminopropionate ammonia-lyase family 45 399 4.4E-94 T 14-10-2018 IPR010081 Diaminopropionate ammonia-lyase GO:0008838|GO:0030170 TSH58p_05440 a25891902542ecea08bb81b805dc3a76 410 SUPERFAMILY SSF53686 47 367 5.24E-60 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TSH58p_05440 a25891902542ecea08bb81b805dc3a76 410 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 47 370 2.0E-63 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TSH58p_05440 a25891902542ecea08bb81b805dc3a76 410 Gene3D G3DSA:3.40.50.1100 46 399 3.4E-137 T 14-10-2018 TSH58p_05440 a25891902542ecea08bb81b805dc3a76 410 Gene3D G3DSA:3.40.50.1100 84 208 3.4E-137 T 14-10-2018 TSH58p_19955 57f5f601165e153b3b22e3d1a9c3cced 562 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 394 546 7.2E-23 T 14-10-2018 IPR006512 YidE/YbjL duplication TSH58p_19955 57f5f601165e153b3b22e3d1a9c3cced 562 Gene3D G3DSA:3.30.70.1450 306 380 1.7E-7 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSH58p_19955 57f5f601165e153b3b22e3d1a9c3cced 562 Gene3D G3DSA:3.30.70.1450 223 292 3.9E-5 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSH58p_19955 57f5f601165e153b3b22e3d1a9c3cced 562 Pfam PF02080 TrkA-C domain 305 372 6.5E-10 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TSH58p_19955 57f5f601165e153b3b22e3d1a9c3cced 562 Pfam PF06826 Predicted Permease Membrane Region 392 558 1.7E-33 T 14-10-2018 IPR006512 YidE/YbjL duplication TSH58p_19955 57f5f601165e153b3b22e3d1a9c3cced 562 Pfam PF06826 Predicted Permease Membrane Region 15 178 5.8E-32 T 14-10-2018 IPR006512 YidE/YbjL duplication TSH58p_19955 57f5f601165e153b3b22e3d1a9c3cced 562 SUPERFAMILY SSF116726 228 290 1.29E-6 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSH58p_19955 57f5f601165e153b3b22e3d1a9c3cced 562 TIGRFAM TIGR03802 Asp_Ala_antiprt: aspartate-alanine antiporter 3 562 1.2E-227 T 14-10-2018 IPR022457 Aspartate-alanine antiporter GO:0005215|GO:0016020 TSH58p_19955 57f5f601165e153b3b22e3d1a9c3cced 562 SUPERFAMILY SSF116726 306 377 1.03E-8 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSH58p_26150 dd10ad4ba44f0262e4731f1ea2e2af54 345 SUPERFAMILY SSF53850 50 277 2.89E-42 T 14-10-2018 TSH58p_26150 dd10ad4ba44f0262e4731f1ea2e2af54 345 SMART SM00062 61 271 0.0053 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_26150 dd10ad4ba44f0262e4731f1ea2e2af54 345 Pfam PF09084 NMT1/THI5 like 64 275 2.6E-21 T 14-10-2018 IPR015168 SsuA/THI5-like TSH58p_26150 dd10ad4ba44f0262e4731f1ea2e2af54 345 Gene3D G3DSA:3.40.190.10 147 342 2.0E-17 T 14-10-2018 TSH58p_26150 dd10ad4ba44f0262e4731f1ea2e2af54 345 Gene3D G3DSA:3.40.190.10 43 146 5.5E-16 T 14-10-2018 TSH58p_24915 444ab86cdf80cf9c2917b7cf4fa42d63 335 TIGRFAM TIGR00552 nadE: NAD+ synthetase 129 313 1.6E-29 T 14-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 TSH58p_24915 444ab86cdf80cf9c2917b7cf4fa42d63 335 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 16 318 50.362 T 14-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 TSH58p_24915 444ab86cdf80cf9c2917b7cf4fa42d63 335 Pfam PF02540 NAD synthase 172 306 8.1E-28 T 14-10-2018 IPR022310 NAD/GMP synthase TSH58p_24915 444ab86cdf80cf9c2917b7cf4fa42d63 335 Pfam PF02540 NAD synthase 22 107 8.0E-19 T 14-10-2018 IPR022310 NAD/GMP synthase TSH58p_24915 444ab86cdf80cf9c2917b7cf4fa42d63 335 SUPERFAMILY SSF52402 6 281 9.01E-51 T 14-10-2018 TSH58p_30610 e1664b0e2d2fb70b08e55ba76a0c038e 112 Gene3D G3DSA:3.30.70.20 3 74 3.6E-12 T 14-10-2018 TSH58p_30610 e1664b0e2d2fb70b08e55ba76a0c038e 112 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 10 21 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_30610 e1664b0e2d2fb70b08e55ba76a0c038e 112 Pfam PF13187 4Fe-4S dicluster domain 9 59 5.1E-8 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_30610 e1664b0e2d2fb70b08e55ba76a0c038e 112 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 45 56 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_30610 e1664b0e2d2fb70b08e55ba76a0c038e 112 SUPERFAMILY SSF54862 4 93 8.94E-16 T 14-10-2018 TSH58p_09760 5d5e2d7799444392a2d08160cf9ad103 394 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 10 383 1.4E-93 T 14-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 TSH58p_09760 5d5e2d7799444392a2d08160cf9ad103 394 Pfam PF07690 Major Facilitator Superfamily 18 356 5.5E-39 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_09760 5d5e2d7799444392a2d08160cf9ad103 394 PRINTS PR01035 Tetracycline resistance protein signature 49 68 1.1E-7 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TSH58p_09760 5d5e2d7799444392a2d08160cf9ad103 394 PRINTS PR01035 Tetracycline resistance protein signature 134 156 1.1E-7 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TSH58p_09760 5d5e2d7799444392a2d08160cf9ad103 394 PRINTS PR01035 Tetracycline resistance protein signature 19 35 1.1E-7 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TSH58p_09760 5d5e2d7799444392a2d08160cf9ad103 394 PRINTS PR01035 Tetracycline resistance protein signature 307 327 1.1E-7 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TSH58p_09760 5d5e2d7799444392a2d08160cf9ad103 394 Gene3D G3DSA:1.20.1720.10 10 386 2.6E-106 T 14-10-2018 TSH58p_09760 5d5e2d7799444392a2d08160cf9ad103 394 SUPERFAMILY SSF103473 8 389 6.41E-58 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_05195 e0726208a9239390645e46f0f0ca3c46 151 Gene3D G3DSA:3.10.580.10 1 143 1.7E-34 T 14-10-2018 TSH58p_05195 e0726208a9239390645e46f0f0ca3c46 151 Pfam PF00571 CBS domain 13 64 1.8E-7 T 14-10-2018 IPR000644 CBS domain TSH58p_05195 e0726208a9239390645e46f0f0ca3c46 151 Pfam PF00571 CBS domain 76 130 4.7E-14 T 14-10-2018 IPR000644 CBS domain TSH58p_05195 e0726208a9239390645e46f0f0ca3c46 151 SUPERFAMILY SSF54631 1 131 3.28E-28 T 14-10-2018 TSH58p_05195 e0726208a9239390645e46f0f0ca3c46 151 SMART SM00116 83 130 1.4E-11 T 14-10-2018 IPR000644 CBS domain TSH58p_05195 e0726208a9239390645e46f0f0ca3c46 151 SMART SM00116 13 65 7.3E-4 T 14-10-2018 IPR000644 CBS domain TSH58p_21395 cd1c93238aa7458a71cb0a1095d3cf83 608 SUPERFAMILY SSF52016 392 593 4.39E-46 T 14-10-2018 TSH58p_21395 cd1c93238aa7458a71cb0a1095d3cf83 608 Gene3D G3DSA:3.50.30.80 392 556 3.8E-34 T 14-10-2018 TSH58p_21395 cd1c93238aa7458a71cb0a1095d3cf83 608 Pfam PF00920 Dehydratase family 56 585 5.9E-152 T 14-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TSH58p_21395 cd1c93238aa7458a71cb0a1095d3cf83 608 SUPERFAMILY SSF143975 15 389 6.02E-116 T 14-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TSH58p_21395 cd1c93238aa7458a71cb0a1095d3cf83 608 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 138 148 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TSH58p_12445 6af7a77a55bede1c34071f752249dce3 528 SUPERFAMILY SSF53756 328 507 1.3E-15 T 14-10-2018 TSH58p_12445 6af7a77a55bede1c34071f752249dce3 528 Pfam PF13692 Glycosyl transferases group 1 354 476 1.1E-7 T 14-10-2018 TSH58p_12445 6af7a77a55bede1c34071f752249dce3 528 Gene3D G3DSA:3.40.50.2000 333 494 6.9E-17 T 14-10-2018 TSH58p_23800 64d374b408039a3d6a1aa8f75971e9a0 370 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 72 314 4.9E-19 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain TSH58p_23800 64d374b408039a3d6a1aa8f75971e9a0 370 SUPERFAMILY SSF111369 139 198 6.67E-5 T 14-10-2018 TSH58p_23800 64d374b408039a3d6a1aa8f75971e9a0 370 Pfam PF00529 HlyD membrane-fusion protein of T1SS 315 364 2.1E-6 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 TSH58p_23800 64d374b408039a3d6a1aa8f75971e9a0 370 Gene3D G3DSA:1.10.287.470 106 133 5.8E-14 T 14-10-2018 TSH58p_23800 64d374b408039a3d6a1aa8f75971e9a0 370 Gene3D G3DSA:2.40.30.170 255 369 6.5E-37 T 14-10-2018 TSH58p_23800 64d374b408039a3d6a1aa8f75971e9a0 370 SUPERFAMILY SSF111369 201 318 6.93E-13 T 14-10-2018 TSH58p_23800 64d374b408039a3d6a1aa8f75971e9a0 370 Gene3D G3DSA:2.40.50.100 73 105 5.8E-14 T 14-10-2018 TSH58p_23800 64d374b408039a3d6a1aa8f75971e9a0 370 Gene3D G3DSA:1.10.287.470 140 206 2.0E-9 T 14-10-2018 TSH58p_23800 64d374b408039a3d6a1aa8f75971e9a0 370 SUPERFAMILY SSF111369 72 128 2.35E-9 T 14-10-2018 TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 Gene3D G3DSA:3.30.450.20 314 432 1.4E-25 T 14-10-2018 TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 Gene3D G3DSA:3.40.50.12740 719 869 5.7E-23 T 14-10-2018 TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 Gene3D G3DSA:3.40.50.12740 883 1017 1.8E-44 T 14-10-2018 TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 SUPERFAMILY SSF55874 508 701 1.96E-45 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 Pfam PF00512 His Kinase A (phospho-acceptor) domain 454 519 1.8E-21 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 Pfam PF01627 Hpt domain 1046 1107 5.4E-10 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 SUPERFAMILY SSF52172 719 841 5.55E-22 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 566 699 4.7E-30 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 SUPERFAMILY SSF47384 438 520 3.53E-22 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 Pfam PF00072 Response regulator receiver domain 887 999 2.9E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 Pfam PF00072 Response regulator receiver domain 722 836 1.6E-11 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 SMART SM00091 318 384 2.4E-9 T 14-10-2018 IPR000014 PAS domain TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 SMART SM00448 720 836 4.7E-13 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 SMART SM00448 885 999 3.0E-38 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 317 441 1.3E-17 T 14-10-2018 IPR000014 PAS domain TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 Gene3D G3DSA:1.10.287.130 433 517 7.1E-29 T 14-10-2018 TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 SUPERFAMILY SSF52172 885 1004 3.13E-39 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 SMART SM00388 454 519 1.2E-26 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 Pfam PF02743 Cache domain 20 267 2.3E-16 T 14-10-2018 IPR033479 Double Cache domain 1 TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 Pfam PF13426 PAS domain 329 433 1.4E-10 T 14-10-2018 IPR000014 PAS domain TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 Gene3D G3DSA:1.20.120.160 1019 1136 2.0E-20 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 Gene3D G3DSA:3.30.450.20 12 178 6.5E-30 T 14-10-2018 TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 Gene3D G3DSA:3.30.565.10 518 701 1.4E-48 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 SUPERFAMILY SSF55785 329 443 3.06E-23 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 SUPERFAMILY SSF47226 982 1111 2.49E-18 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 PRINTS PR00344 Bacterial sensor protein C-terminal signature 626 640 2.6E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 PRINTS PR00344 Bacterial sensor protein C-terminal signature 685 698 2.6E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 PRINTS PR00344 Bacterial sensor protein C-terminal signature 644 654 2.6E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 PRINTS PR00344 Bacterial sensor protein C-terminal signature 661 679 2.6E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 Gene3D G3DSA:3.30.450.20 181 271 1.6E-15 T 14-10-2018 TSH58p_03915 152e7ad30260ee48fb8561d0d65fbd91 1157 SMART SM00387 566 701 2.2E-37 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_21345 6e6ce0c5ba3403b3f49c838ca7e52a93 516 ProSitePatterns PS00211 ABC transporters family signature. 410 424 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_21345 6e6ce0c5ba3403b3f49c838ca7e52a93 516 SMART SM00382 37 224 1.1E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_21345 6e6ce0c5ba3403b3f49c838ca7e52a93 516 SMART SM00382 292 494 0.0061 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_21345 6e6ce0c5ba3403b3f49c838ca7e52a93 516 Pfam PF00005 ABC transporter 286 437 4.1E-17 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_21345 6e6ce0c5ba3403b3f49c838ca7e52a93 516 SUPERFAMILY SSF52540 11 235 2.4E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_21345 6e6ce0c5ba3403b3f49c838ca7e52a93 516 SUPERFAMILY SSF52540 276 495 6.57E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_21345 6e6ce0c5ba3403b3f49c838ca7e52a93 516 Gene3D G3DSA:3.40.50.300 259 504 1.3E-43 T 14-10-2018 TSH58p_21345 6e6ce0c5ba3403b3f49c838ca7e52a93 516 Gene3D G3DSA:3.40.50.300 2 255 4.5E-58 T 14-10-2018 TSH58p_21345 6e6ce0c5ba3403b3f49c838ca7e52a93 516 Pfam PF00005 ABC transporter 28 177 2.2E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_01800 fc36df7114c74f4d06dfd57d53e4f8ad 473 TIGRFAM TIGR02022 hutF: formiminoglutamate deiminase 14 470 1.3E-195 T 14-10-2018 IPR010252 Formiminoglutamate deiminase TSH58p_01800 fc36df7114c74f4d06dfd57d53e4f8ad 473 SUPERFAMILY SSF51338 376 471 1.75E-11 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_01800 fc36df7114c74f4d06dfd57d53e4f8ad 473 Pfam PF01979 Amidohydrolase family 59 446 4.4E-33 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TSH58p_01800 fc36df7114c74f4d06dfd57d53e4f8ad 473 Gene3D G3DSA:2.30.40.10 20 450 8.1E-184 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_01800 fc36df7114c74f4d06dfd57d53e4f8ad 473 SUPERFAMILY SSF51556 61 391 4.54E-70 T 14-10-2018 IPR032466 Metal-dependent hydrolase TSH58p_01800 fc36df7114c74f4d06dfd57d53e4f8ad 473 Gene3D G3DSA:3.20.20.140 63 462 8.1E-184 T 14-10-2018 TSH58p_06945 dac97c4ce8e88af046a6ef83af6f508d 67 Gene3D G3DSA:1.10.3990.20 1 66 9.2E-16 T 14-10-2018 IPR038268 Ribbon-helix-helix domain superfamily TSH58p_06945 dac97c4ce8e88af046a6ef83af6f508d 67 Pfam PF13467 Ribbon-helix-helix domain 1 62 1.1E-26 T 14-10-2018 IPR027373 Ribbon-helix-helix domain TSH58p_00490 36c46fc58226cae44e03954e07e62a60 549 SUPERFAMILY SSF51905 7 444 1.91E-56 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_00490 36c46fc58226cae44e03954e07e62a60 549 Gene3D G3DSA:3.30.70.20 448 543 6.0E-41 T 14-10-2018 TSH58p_00490 36c46fc58226cae44e03954e07e62a60 549 Gene3D G3DSA:3.30.9.90 82 447 1.8E-206 T 14-10-2018 TSH58p_00490 36c46fc58226cae44e03954e07e62a60 549 SUPERFAMILY SSF54862 447 546 7.48E-29 T 14-10-2018 TSH58p_00490 36c46fc58226cae44e03954e07e62a60 549 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 443 545 2.0E-51 T 14-10-2018 TSH58p_00490 36c46fc58226cae44e03954e07e62a60 549 Pfam PF13450 NAD(P)-binding Rossmann-like domain 15 60 1.5E-6 T 14-10-2018 TSH58p_00490 36c46fc58226cae44e03954e07e62a60 549 SUPERFAMILY SSF54373 211 307 1.49E-36 T 14-10-2018 TSH58p_00490 36c46fc58226cae44e03954e07e62a60 549 Gene3D G3DSA:3.50.50.60 10 385 1.8E-206 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_20405 75b88bd3716bd72d6041a96507424e18 391 Pfam PF02803 Thiolase, C-terminal domain 268 390 1.3E-52 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 TSH58p_20405 75b88bd3716bd72d6041a96507424e18 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 389 5.8E-144 T 14-10-2018 IPR002155 Thiolase GO:0016747 TSH58p_20405 75b88bd3716bd72d6041a96507424e18 391 Gene3D G3DSA:3.40.47.10 126 387 1.5E-153 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_20405 75b88bd3716bd72d6041a96507424e18 391 SUPERFAMILY SSF53901 3 267 3.76E-85 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_20405 75b88bd3716bd72d6041a96507424e18 391 PIRSF PIRSF000429 1 391 4.4E-126 T 14-10-2018 IPR002155 Thiolase GO:0016747 TSH58p_20405 75b88bd3716bd72d6041a96507424e18 391 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 14-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 TSH58p_20405 75b88bd3716bd72d6041a96507424e18 391 Pfam PF00108 Thiolase, N-terminal domain 4 260 6.4E-104 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 TSH58p_20405 75b88bd3716bd72d6041a96507424e18 391 ProSitePatterns PS00737 Thiolases signature 2. 337 353 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 TSH58p_20405 75b88bd3716bd72d6041a96507424e18 391 Gene3D G3DSA:3.40.47.10 5 274 1.5E-153 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_20405 75b88bd3716bd72d6041a96507424e18 391 SUPERFAMILY SSF53901 269 390 5.13E-46 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_20405 75b88bd3716bd72d6041a96507424e18 391 ProSitePatterns PS00099 Thiolases active site. 372 385 - T 14-10-2018 IPR020610 Thiolase, active site GO:0016747 TSH58p_04030 3d6f6e7f476c5848ef4f2a8c01aaf9c5 188 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 147 24.652 T 14-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_04030 3d6f6e7f476c5848ef4f2a8c01aaf9c5 188 SUPERFAMILY SSF55658 1 55 3.49E-18 T 14-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal TSH58p_04030 3d6f6e7f476c5848ef4f2a8c01aaf9c5 188 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 14-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_04030 3d6f6e7f476c5848ef4f2a8c01aaf9c5 188 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 145 1.0E-38 T 14-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_04030 3d6f6e7f476c5848ef4f2a8c01aaf9c5 188 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 145 3.6E-26 T 14-10-2018 IPR020069 Ribosomal protein L9, C-terminal TSH58p_04030 3d6f6e7f476c5848ef4f2a8c01aaf9c5 188 Gene3D G3DSA:3.10.430.100 60 147 2.0E-25 T 14-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily TSH58p_04030 3d6f6e7f476c5848ef4f2a8c01aaf9c5 188 Gene3D G3DSA:3.40.5.10 1 50 4.7E-23 T 14-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_04030 3d6f6e7f476c5848ef4f2a8c01aaf9c5 188 SUPERFAMILY SSF55653 58 147 4.97E-25 T 14-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily TSH58p_04030 3d6f6e7f476c5848ef4f2a8c01aaf9c5 188 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 45 4.7E-22 T 14-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_04860 652be5f0aea2a4a3a1d68bc1185dff23 252 SUPERFAMILY SSF53448 11 238 9.38E-42 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_04860 652be5f0aea2a4a3a1d68bc1185dff23 252 Gene3D G3DSA:3.90.550.10 2 241 1.1E-38 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_04860 652be5f0aea2a4a3a1d68bc1185dff23 252 Pfam PF00535 Glycosyl transferase family 2 14 179 3.1E-26 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_02060 6021c9e933105e20c2b06d5835860eb4 352 SUPERFAMILY SSF111369 52 198 3.4E-14 T 14-10-2018 TSH58p_02060 6021c9e933105e20c2b06d5835860eb4 352 Gene3D G3DSA:1.10.287.470 92 165 1.8E-33 T 14-10-2018 TSH58p_02060 6021c9e933105e20c2b06d5835860eb4 352 Gene3D G3DSA:2.40.50.100 58 203 1.8E-33 T 14-10-2018 TSH58p_02060 6021c9e933105e20c2b06d5835860eb4 352 Gene3D G3DSA:2.40.30.170 43 287 1.8E-33 T 14-10-2018 TSH58p_02060 6021c9e933105e20c2b06d5835860eb4 352 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 36 347 1.0E-35 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 TSH58p_02060 6021c9e933105e20c2b06d5835860eb4 352 Gene3D G3DSA:2.40.420.20 37 347 1.8E-33 T 14-10-2018 TSH58p_02060 6021c9e933105e20c2b06d5835860eb4 352 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 61 226 4.7E-12 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain TSH58p_31535 29c9078d559c1100cd932588d01660d5 293 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_31535 29c9078d559c1100cd932588d01660d5 293 Pfam PF00005 ABC transporter 51 196 8.0E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_31535 29c9078d559c1100cd932588d01660d5 293 Gene3D G3DSA:3.40.50.300 27 270 9.3E-62 T 14-10-2018 TSH58p_31535 29c9078d559c1100cd932588d01660d5 293 SMART SM00382 58 256 7.6E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_31535 29c9078d559c1100cd932588d01660d5 293 SUPERFAMILY SSF52540 29 266 1.57E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_03850 e763c8a8e9f61f6000a605d3f3157006 130 Pfam PF13411 MerR HTH family regulatory protein 5 70 1.1E-17 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_03850 e763c8a8e9f61f6000a605d3f3157006 130 SMART SM00422 5 72 7.9E-23 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_03850 e763c8a8e9f61f6000a605d3f3157006 130 SUPERFAMILY SSF46955 4 108 1.06E-25 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily TSH58p_03850 e763c8a8e9f61f6000a605d3f3157006 130 Gene3D G3DSA:1.10.1660.10 4 128 3.3E-28 T 14-10-2018 TSH58p_02945 1c2ecb22f13b95af33c03c3befdf46ef 466 Pfam PF01425 Amidase 25 449 5.4E-100 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_02945 1c2ecb22f13b95af33c03c3befdf46ef 466 SUPERFAMILY SSF75304 4 458 8.9E-129 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_02945 1c2ecb22f13b95af33c03c3befdf46ef 466 Gene3D G3DSA:3.90.1300.10 1 463 2.5E-139 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_23000 fee1b80e3292bf0a45c2bc8428c795d9 316 SUPERFAMILY SSF46894 250 311 1.73E-20 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_23000 fee1b80e3292bf0a45c2bc8428c795d9 316 Pfam PF00072 Response regulator receiver domain 13 123 6.8E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_23000 fee1b80e3292bf0a45c2bc8428c795d9 316 Gene3D G3DSA:3.40.50.12740 12 234 1.2E-41 T 14-10-2018 TSH58p_23000 fee1b80e3292bf0a45c2bc8428c795d9 316 SUPERFAMILY SSF52172 13 144 1.11E-38 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_23000 fee1b80e3292bf0a45c2bc8428c795d9 316 SMART SM00421 252 309 1.1E-23 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_23000 fee1b80e3292bf0a45c2bc8428c795d9 316 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 269 285 3.2E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_23000 fee1b80e3292bf0a45c2bc8428c795d9 316 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 255 269 3.2E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_23000 fee1b80e3292bf0a45c2bc8428c795d9 316 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 285 297 3.2E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_23000 fee1b80e3292bf0a45c2bc8428c795d9 316 Gene3D G3DSA:1.10.10.10 246 315 6.0E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_23000 fee1b80e3292bf0a45c2bc8428c795d9 316 SMART SM00448 11 124 6.8E-35 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_23000 fee1b80e3292bf0a45c2bc8428c795d9 316 Pfam PF00196 Bacterial regulatory proteins, luxR family 254 309 1.0E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_00485 20a4acca7ca7fcde09dedf348e424e54 275 SUPERFAMILY SSF52402 1 138 1.67E-14 T 14-10-2018 TSH58p_00485 20a4acca7ca7fcde09dedf348e424e54 275 Pfam PF00582 Universal stress protein family 3 138 5.5E-9 T 14-10-2018 IPR006016 UspA TSH58p_00485 20a4acca7ca7fcde09dedf348e424e54 275 Pfam PF00582 Universal stress protein family 152 273 6.8E-6 T 14-10-2018 IPR006016 UspA TSH58p_00485 20a4acca7ca7fcde09dedf348e424e54 275 Gene3D G3DSA:3.40.50.12370 5 274 1.1E-34 T 14-10-2018 TSH58p_00485 20a4acca7ca7fcde09dedf348e424e54 275 SUPERFAMILY SSF52402 150 273 3.27E-12 T 14-10-2018 TSH58p_31045 e750130b2d15a308d977870963c71884 313 Pfam PF13533 Biotin-lipoyl like 47 94 6.7E-17 T 14-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain TSH58p_31045 e750130b2d15a308d977870963c71884 313 Gene3D G3DSA:2.40.30.170 169 293 2.3E-27 T 14-10-2018 TSH58p_31045 e750130b2d15a308d977870963c71884 313 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 44 237 1.6E-30 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 TSH58p_31045 e750130b2d15a308d977870963c71884 313 Gene3D G3DSA:2.40.50.100 46 118 8.8E-9 T 14-10-2018 TSH58p_31045 e750130b2d15a308d977870963c71884 313 SUPERFAMILY SSF111369 44 186 2.62E-20 T 14-10-2018 TSH58p_31045 e750130b2d15a308d977870963c71884 313 Pfam PF13437 HlyD family secretion protein 155 238 3.3E-9 T 14-10-2018 TSH58p_16045 57ca59a27ffb2ab434aaf48be5b11886 207 SUPERFAMILY SSF110111 62 185 4.05E-52 T 14-10-2018 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16045 57ca59a27ffb2ab434aaf48be5b11886 207 Gene3D G3DSA:2.60.370.10 56 199 9.1E-60 T 14-10-2018 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16045 57ca59a27ffb2ab434aaf48be5b11886 207 Hamap MF_00155 Cytochrome c oxidase assembly protein CtaG [ctaG]. 1 187 40.964 T 14-10-2018 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16045 57ca59a27ffb2ab434aaf48be5b11886 207 Pfam PF04442 Cytochrome c oxidase assembly protein CtaG/Cox11 36 181 1.6E-60 T 14-10-2018 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16045 57ca59a27ffb2ab434aaf48be5b11886 207 PIRSF PIRSF005413 3 198 5.0E-76 T 14-10-2018 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_28700 a988fb5f72425b10bc040bf0090d0ae4 217 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 107 2.4E-28 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 TSH58p_28700 a988fb5f72425b10bc040bf0090d0ae4 217 Gene3D G3DSA:1.10.3720.10 6 214 8.8E-47 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_28700 a988fb5f72425b10bc040bf0090d0ae4 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 211 6.3E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_28700 a988fb5f72425b10bc040bf0090d0ae4 217 SUPERFAMILY SSF161098 13 198 4.84E-41 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_11565 10e6d3b383d67041ae3ab7bc9560888f 542 Gene3D G3DSA:2.60.40.1220 24 120 8.8E-14 T 14-10-2018 TSH58p_11565 10e6d3b383d67041ae3ab7bc9560888f 542 Pfam PF05425 Copper resistance protein D 312 412 2.9E-21 T 14-10-2018 IPR008457 Copper resistance protein D GO:0016021 TSH58p_11565 10e6d3b383d67041ae3ab7bc9560888f 542 Pfam PF04234 CopC domain 24 114 2.5E-17 T 14-10-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 TSH58p_11565 10e6d3b383d67041ae3ab7bc9560888f 542 SUPERFAMILY SSF81296 23 115 4.4E-18 T 14-10-2018 IPR014756 Immunoglobulin E-set TSH58p_03900 5d1c2bdbd8e246c720d7aa48b2371796 540 Gene3D G3DSA:3.30.70.270 373 539 3.6E-58 T 14-10-2018 TSH58p_03900 5d1c2bdbd8e246c720d7aa48b2371796 540 Pfam PF00990 Diguanylate cyclase, GGDEF domain 375 532 6.7E-46 T 14-10-2018 IPR000160 GGDEF domain TSH58p_03900 5d1c2bdbd8e246c720d7aa48b2371796 540 Gene3D G3DSA:3.30.450.20 256 372 2.1E-20 T 14-10-2018 TSH58p_03900 5d1c2bdbd8e246c720d7aa48b2371796 540 SUPERFAMILY SSF55785 251 345 2.37E-18 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_03900 5d1c2bdbd8e246c720d7aa48b2371796 540 SMART SM00267 364 536 2.3E-61 T 14-10-2018 IPR000160 GGDEF domain TSH58p_03900 5d1c2bdbd8e246c720d7aa48b2371796 540 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 372 535 6.8E-52 T 14-10-2018 IPR000160 GGDEF domain TSH58p_03900 5d1c2bdbd8e246c720d7aa48b2371796 540 SUPERFAMILY SSF55785 119 246 7.15E-18 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_03900 5d1c2bdbd8e246c720d7aa48b2371796 540 Gene3D G3DSA:3.30.450.20 136 246 3.3E-14 T 14-10-2018 TSH58p_03900 5d1c2bdbd8e246c720d7aa48b2371796 540 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 17 129 3.0E-6 T 14-10-2018 IPR000014 PAS domain TSH58p_03900 5d1c2bdbd8e246c720d7aa48b2371796 540 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 139 247 2.3E-7 T 14-10-2018 IPR000014 PAS domain TSH58p_03900 5d1c2bdbd8e246c720d7aa48b2371796 540 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 251 371 7.8E-20 T 14-10-2018 IPR000014 PAS domain TSH58p_03900 5d1c2bdbd8e246c720d7aa48b2371796 540 Pfam PF08448 PAS fold 140 247 1.1E-9 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_03900 5d1c2bdbd8e246c720d7aa48b2371796 540 SUPERFAMILY SSF55073 380 538 2.2E-49 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_03900 5d1c2bdbd8e246c720d7aa48b2371796 540 Gene3D G3DSA:3.30.450.20 20 133 1.9E-12 T 14-10-2018 TSH58p_03900 5d1c2bdbd8e246c720d7aa48b2371796 540 SMART SM00091 134 200 9.7E-5 T 14-10-2018 IPR000014 PAS domain TSH58p_03900 5d1c2bdbd8e246c720d7aa48b2371796 540 SMART SM00091 253 321 1.2E-9 T 14-10-2018 IPR000014 PAS domain TSH58p_03900 5d1c2bdbd8e246c720d7aa48b2371796 540 SMART SM00091 19 85 0.0013 T 14-10-2018 IPR000014 PAS domain TSH58p_03900 5d1c2bdbd8e246c720d7aa48b2371796 540 Pfam PF00989 PAS fold 23 71 3.2E-6 T 14-10-2018 IPR013767 PAS fold GO:0006355 TSH58p_03900 5d1c2bdbd8e246c720d7aa48b2371796 540 Pfam PF00989 PAS fold 253 343 4.9E-13 T 14-10-2018 IPR013767 PAS fold GO:0006355 TSH58p_03900 5d1c2bdbd8e246c720d7aa48b2371796 540 SUPERFAMILY SSF55785 15 120 2.79E-13 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_20480 48ec6f1a68e9729935734fabfd27d3cc 325 Gene3D G3DSA:3.40.50.1820 28 308 5.5E-48 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_20480 48ec6f1a68e9729935734fabfd27d3cc 325 PRINTS PR00111 Alpha/beta hydrolase fold signature 84 99 1.0E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_20480 48ec6f1a68e9729935734fabfd27d3cc 325 PRINTS PR00111 Alpha/beta hydrolase fold signature 246 260 1.0E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_20480 48ec6f1a68e9729935734fabfd27d3cc 325 PRINTS PR00111 Alpha/beta hydrolase fold signature 132 145 1.0E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_20480 48ec6f1a68e9729935734fabfd27d3cc 325 Pfam PF12146 Serine aminopeptidase, S33 55 291 2.7E-56 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 TSH58p_20480 48ec6f1a68e9729935734fabfd27d3cc 325 SUPERFAMILY SSF53474 18 305 3.89E-37 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_19050 85853987c6f3bce2765cdaae1f1777b5 507 Gene3D G3DSA:2.40.33.10 79 175 6.6E-167 T 14-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_19050 85853987c6f3bce2765cdaae1f1777b5 507 PRINTS PR01050 Pyruvate kinase family signature 272 296 1.4E-64 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_19050 85853987c6f3bce2765cdaae1f1777b5 507 PRINTS PR01050 Pyruvate kinase family signature 297 315 1.4E-64 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_19050 85853987c6f3bce2765cdaae1f1777b5 507 PRINTS PR01050 Pyruvate kinase family signature 193 207 1.4E-64 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_19050 85853987c6f3bce2765cdaae1f1777b5 507 PRINTS PR01050 Pyruvate kinase family signature 247 271 1.4E-64 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_19050 85853987c6f3bce2765cdaae1f1777b5 507 PRINTS PR01050 Pyruvate kinase family signature 68 84 1.4E-64 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_19050 85853987c6f3bce2765cdaae1f1777b5 507 PRINTS PR01050 Pyruvate kinase family signature 220 246 1.4E-64 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_19050 85853987c6f3bce2765cdaae1f1777b5 507 PRINTS PR01050 Pyruvate kinase family signature 316 332 1.4E-64 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_19050 85853987c6f3bce2765cdaae1f1777b5 507 SUPERFAMILY SSF52935 326 476 1.44E-37 T 14-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_19050 85853987c6f3bce2765cdaae1f1777b5 507 Pfam PF02887 Pyruvate kinase, alpha/beta domain 361 473 3.3E-29 T 14-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_19050 85853987c6f3bce2765cdaae1f1777b5 507 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 11 474 6.8E-150 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_19050 85853987c6f3bce2765cdaae1f1777b5 507 Pfam PF00224 Pyruvate kinase, barrel domain 11 340 6.2E-108 T 14-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_19050 85853987c6f3bce2765cdaae1f1777b5 507 SUPERFAMILY SSF50800 79 174 2.62E-22 T 14-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily TSH58p_19050 85853987c6f3bce2765cdaae1f1777b5 507 Gene3D G3DSA:3.20.20.60 11 338 6.6E-167 T 14-10-2018 TSH58p_19050 85853987c6f3bce2765cdaae1f1777b5 507 SUPERFAMILY SSF51621 5 345 2.51E-96 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSH58p_19050 85853987c6f3bce2765cdaae1f1777b5 507 Gene3D G3DSA:3.40.1380.20 339 472 6.6E-167 T 14-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_06670 1d37ed347a40f07229735ffaa0c746a9 742 Gene3D G3DSA:3.40.50.880 542 731 3.4E-50 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_06670 1d37ed347a40f07229735ffaa0c746a9 742 SUPERFAMILY SSF56322 24 521 1.83E-115 T 14-10-2018 IPR005801 ADC synthase GO:0009058 TSH58p_06670 1d37ed347a40f07229735ffaa0c746a9 742 SUPERFAMILY SSF52317 539 729 5.42E-46 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_06670 1d37ed347a40f07229735ffaa0c746a9 742 Pfam PF00425 chorismate binding enzyme 257 513 9.8E-62 T 14-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal TSH58p_06670 1d37ed347a40f07229735ffaa0c746a9 742 PRINTS PR00097 Anthranilate synthase component II signature 640 648 8.3E-24 T 14-10-2018 TSH58p_06670 1d37ed347a40f07229735ffaa0c746a9 742 PRINTS PR00097 Anthranilate synthase component II signature 544 558 8.3E-24 T 14-10-2018 TSH58p_06670 1d37ed347a40f07229735ffaa0c746a9 742 PRINTS PR00097 Anthranilate synthase component II signature 615 626 8.3E-24 T 14-10-2018 TSH58p_06670 1d37ed347a40f07229735ffaa0c746a9 742 PRINTS PR00097 Anthranilate synthase component II signature 660 672 8.3E-24 T 14-10-2018 TSH58p_06670 1d37ed347a40f07229735ffaa0c746a9 742 PRINTS PR00097 Anthranilate synthase component II signature 705 718 8.3E-24 T 14-10-2018 TSH58p_06670 1d37ed347a40f07229735ffaa0c746a9 742 PRINTS PR00097 Anthranilate synthase component II signature 588 597 8.3E-24 T 14-10-2018 TSH58p_06670 1d37ed347a40f07229735ffaa0c746a9 742 Gene3D G3DSA:3.60.120.10 30 526 1.2E-119 T 14-10-2018 IPR005801 ADC synthase GO:0009058 TSH58p_06670 1d37ed347a40f07229735ffaa0c746a9 742 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 544 728 1.1E-38 T 14-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TSH58p_06670 1d37ed347a40f07229735ffaa0c746a9 742 PRINTS PR00096 Glutamine amidotransferase superfamily signature 705 718 3.2E-10 T 14-10-2018 TSH58p_06670 1d37ed347a40f07229735ffaa0c746a9 742 PRINTS PR00096 Glutamine amidotransferase superfamily signature 615 626 3.2E-10 T 14-10-2018 TSH58p_06670 1d37ed347a40f07229735ffaa0c746a9 742 PRINTS PR00096 Glutamine amidotransferase superfamily signature 588 597 3.2E-10 T 14-10-2018 TSH58p_06670 1d37ed347a40f07229735ffaa0c746a9 742 PIRSF PIRSF036934 6 742 0.0 T 14-10-2018 IPR010112 Anthranilate synthase GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TSH58p_06670 1d37ed347a40f07229735ffaa0c746a9 742 TIGRFAM TIGR01815 TrpE-clade3: anthranilate synthase 18 741 0.0 T 14-10-2018 IPR010112 Anthranilate synthase GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TSH58p_06670 1d37ed347a40f07229735ffaa0c746a9 742 Pfam PF00117 Glutamine amidotransferase class-I 546 720 4.7E-38 T 14-10-2018 IPR017926 Glutamine amidotransferase TSH58p_06670 1d37ed347a40f07229735ffaa0c746a9 742 Pfam PF04715 Anthranilate synthase component I, N terminal region 111 204 4.5E-6 T 14-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TSH58p_01370 5f29ee2c36239a5a5884ca4db0afe126 282 SUPERFAMILY SSF46785 24 97 2.09E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_01370 5f29ee2c36239a5a5884ca4db0afe126 282 Gene3D G3DSA:1.10.10.10 21 95 8.8E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_01370 5f29ee2c36239a5a5884ca4db0afe126 282 SUPERFAMILY SSF55781 81 265 2.75E-29 T 14-10-2018 TSH58p_01370 5f29ee2c36239a5a5884ca4db0afe126 282 Pfam PF09339 IclR helix-turn-helix domain 28 74 7.9E-10 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TSH58p_01370 5f29ee2c36239a5a5884ca4db0afe126 282 Gene3D G3DSA:3.30.450.40 96 269 3.1E-31 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_01370 5f29ee2c36239a5a5884ca4db0afe126 282 SMART SM00346 23 113 5.2E-13 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TSH58p_01370 5f29ee2c36239a5a5884ca4db0afe126 282 Pfam PF01614 Bacterial transcriptional regulator 142 261 3.8E-14 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal TSH58p_14290 6fe4cc6c0a4727f19f98fa168184215d 423 SUPERFAMILY SSF53067 20 206 1.52E-51 T 14-10-2018 TSH58p_14290 6fe4cc6c0a4727f19f98fa168184215d 423 Gene3D G3DSA:3.30.1490.110 96 178 4.1E-105 T 14-10-2018 TSH58p_14290 6fe4cc6c0a4727f19f98fa168184215d 423 Gene3D G3DSA:3.30.420.40 24 384 4.1E-105 T 14-10-2018 TSH58p_14290 6fe4cc6c0a4727f19f98fa168184215d 423 Gene3D G3DSA:3.90.640.10 244 312 4.1E-105 T 14-10-2018 TSH58p_14290 6fe4cc6c0a4727f19f98fa168184215d 423 SUPERFAMILY SSF53067 208 389 7.07E-44 T 14-10-2018 TSH58p_14290 6fe4cc6c0a4727f19f98fa168184215d 423 PIRSF PIRSF003101 10 416 1.9E-132 T 14-10-2018 IPR020823 Cell division protein FtsA TSH58p_14290 6fe4cc6c0a4727f19f98fa168184215d 423 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 21 389 1.8E-113 T 14-10-2018 IPR020823 Cell division protein FtsA TSH58p_14290 6fe4cc6c0a4727f19f98fa168184215d 423 Pfam PF02491 SHS2 domain inserted in FTSA 99 171 1.5E-22 T 14-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 TSH58p_14290 6fe4cc6c0a4727f19f98fa168184215d 423 Gene3D G3DSA:3.30.420.40 206 364 4.1E-105 T 14-10-2018 TSH58p_14290 6fe4cc6c0a4727f19f98fa168184215d 423 Pfam PF14450 Cell division protein FtsA 22 204 3.1E-9 T 14-10-2018 TSH58p_14290 6fe4cc6c0a4727f19f98fa168184215d 423 SMART SM00842 21 205 5.9E-83 T 14-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 TSH58p_14290 6fe4cc6c0a4727f19f98fa168184215d 423 Pfam PF14450 Cell division protein FtsA 216 386 6.9E-23 T 14-10-2018 TSH58p_14290 6fe4cc6c0a4727f19f98fa168184215d 423 Hamap MF_02033 Cell division protein FtsA [ftsA]. 17 423 26.641 T 14-10-2018 IPR020823 Cell division protein FtsA TSH58p_30885 8e676f6d13e236c20899be918d397360 277 SMART SM00382 54 245 8.2E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_30885 8e676f6d13e236c20899be918d397360 277 SUPERFAMILY SSF52540 39 259 2.1E-71 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_30885 8e676f6d13e236c20899be918d397360 277 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_30885 8e676f6d13e236c20899be918d397360 277 Pfam PF00005 ABC transporter 46 182 9.9E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_30885 8e676f6d13e236c20899be918d397360 277 Gene3D G3DSA:3.40.50.300 21 240 1.5E-59 T 14-10-2018 TSH58p_14335 4b541bcf85ae804d986df5e8b3e551c1 467 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 113 136 - T 14-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 TSH58p_14335 4b541bcf85ae804d986df5e8b3e551c1 467 Gene3D G3DSA:3.40.1190.10 98 316 2.0E-52 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TSH58p_14335 4b541bcf85ae804d986df5e8b3e551c1 467 SUPERFAMILY SSF51984 7 95 1.2E-11 T 14-10-2018 TSH58p_14335 4b541bcf85ae804d986df5e8b3e551c1 467 Pfam PF02875 Mur ligase family, glutamate ligase domain 318 366 1.0E-5 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 TSH58p_14335 4b541bcf85ae804d986df5e8b3e551c1 467 Gene3D G3DSA:3.40.50.720 7 97 1.9E-15 T 14-10-2018 TSH58p_14335 4b541bcf85ae804d986df5e8b3e551c1 467 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 7 61 1.5E-4 T 14-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TSH58p_14335 4b541bcf85ae804d986df5e8b3e551c1 467 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 10 457 31.533 T 14-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TSH58p_14335 4b541bcf85ae804d986df5e8b3e551c1 467 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 12 455 2.5E-110 T 14-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TSH58p_14335 4b541bcf85ae804d986df5e8b3e551c1 467 Gene3D G3DSA:3.90.190.20 322 462 2.5E-40 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TSH58p_14335 4b541bcf85ae804d986df5e8b3e551c1 467 SUPERFAMILY SSF53244 316 457 5.04E-37 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TSH58p_14335 4b541bcf85ae804d986df5e8b3e551c1 467 Pfam PF08245 Mur ligase middle domain 115 297 1.6E-29 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 TSH58p_14335 4b541bcf85ae804d986df5e8b3e551c1 467 SUPERFAMILY SSF53623 105 314 7.98E-48 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TSH58p_32640 af8981851925ac3071fb5baec7dca02f 669 Pfam PF01032 FecCD transport family 22 330 4.0E-64 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TSH58p_32640 af8981851925ac3071fb5baec7dca02f 669 Pfam PF01032 FecCD transport family 391 666 1.1E-66 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TSH58p_32640 af8981851925ac3071fb5baec7dca02f 669 Gene3D G3DSA:1.10.3470.10 348 669 6.8E-69 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_32640 af8981851925ac3071fb5baec7dca02f 669 SUPERFAMILY SSF81345 15 332 1.7E-56 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_32640 af8981851925ac3071fb5baec7dca02f 669 Gene3D G3DSA:1.10.3470.10 16 337 1.3E-65 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_32640 af8981851925ac3071fb5baec7dca02f 669 SUPERFAMILY SSF81345 352 667 1.96E-59 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_30190 af8981851925ac3071fb5baec7dca02f 669 Pfam PF01032 FecCD transport family 22 330 4.0E-64 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TSH58p_30190 af8981851925ac3071fb5baec7dca02f 669 Pfam PF01032 FecCD transport family 391 666 1.1E-66 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TSH58p_30190 af8981851925ac3071fb5baec7dca02f 669 Gene3D G3DSA:1.10.3470.10 348 669 6.8E-69 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_30190 af8981851925ac3071fb5baec7dca02f 669 SUPERFAMILY SSF81345 15 332 1.7E-56 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_30190 af8981851925ac3071fb5baec7dca02f 669 Gene3D G3DSA:1.10.3470.10 16 337 1.3E-65 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_30190 af8981851925ac3071fb5baec7dca02f 669 SUPERFAMILY SSF81345 352 667 1.96E-59 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 Gene3D G3DSA:3.30.450.40 25 165 2.4E-12 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 SMART SM00388 432 497 1.3E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 SMART SM00086 254 297 7.8 T 14-10-2018 IPR001610 PAC motif TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 SMART SM00086 378 419 6.5E-5 T 14-10-2018 IPR001610 PAC motif TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 Gene3D G3DSA:1.10.287.130 415 495 3.4E-16 T 14-10-2018 TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 SUPERFAMILY SSF47384 417 497 5.3E-16 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 SMART SM00065 28 171 0.0019 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 SUPERFAMILY SSF55785 294 416 1.22E-23 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 Gene3D G3DSA:3.30.450.20 306 414 5.9E-24 T 14-10-2018 TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 SUPERFAMILY SSF55785 171 295 1.74E-24 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 PRINTS PR00344 Bacterial sensor protein C-terminal signature 577 591 1.0E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 PRINTS PR00344 Bacterial sensor protein C-terminal signature 636 649 1.0E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 PRINTS PR00344 Bacterial sensor protein C-terminal signature 595 605 1.0E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 PRINTS PR00344 Bacterial sensor protein C-terminal signature 612 630 1.0E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 Pfam PF00512 His Kinase A (phospho-acceptor) domain 432 497 6.9E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 Gene3D G3DSA:3.40.50.2300 679 798 4.2E-18 T 14-10-2018 TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 Gene3D G3DSA:3.30.450.20 166 305 5.1E-33 T 14-10-2018 TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 Pfam PF08448 PAS fold 188 299 7.6E-23 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 SMART SM00448 678 792 2.7E-9 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 SMART SM00091 182 248 5.8E-10 T 14-10-2018 IPR000014 PAS domain TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 SMART SM00091 309 372 0.2 T 14-10-2018 IPR000014 PAS domain TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 Pfam PF01590 GAF domain 30 157 2.1E-7 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 SUPERFAMILY SSF55781 30 173 4.71E-21 T 14-10-2018 TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 SUPERFAMILY SSF52172 681 797 8.25E-19 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 Gene3D G3DSA:3.30.565.10 497 655 8.4E-32 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 Pfam PF08447 PAS fold 341 413 5.4E-12 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 542 650 1.2E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 SMART SM00387 541 652 1.3E-28 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 Pfam PF00072 Response regulator receiver domain 681 792 1.1E-7 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 179 304 6.2E-24 T 14-10-2018 IPR000014 PAS domain TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 305 425 4.3E-16 T 14-10-2018 IPR000014 PAS domain TSH58p_00860 3e446d24e35319d8fb5cd70bbf27d721 802 SUPERFAMILY SSF55874 486 654 1.57E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_04790 bd37ed76701ac6dce101f592198abdb0 346 PRINTS PR01021 OMPA domain signature 273 288 3.9E-12 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 TSH58p_04790 bd37ed76701ac6dce101f592198abdb0 346 PRINTS PR01021 OMPA domain signature 243 265 3.9E-12 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 TSH58p_04790 bd37ed76701ac6dce101f592198abdb0 346 PRINTS PR01021 OMPA domain signature 288 304 3.9E-12 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 TSH58p_04790 bd37ed76701ac6dce101f592198abdb0 346 Gene3D G3DSA:2.40.160.20 22 213 1.9E-32 T 14-10-2018 TSH58p_04790 bd37ed76701ac6dce101f592198abdb0 346 Pfam PF00691 OmpA family 242 337 5.9E-18 T 14-10-2018 IPR006665 OmpA-like domain TSH58p_04790 bd37ed76701ac6dce101f592198abdb0 346 Gene3D G3DSA:3.30.1330.60 226 343 4.7E-29 T 14-10-2018 IPR036737 OmpA-like domain superfamily TSH58p_04790 bd37ed76701ac6dce101f592198abdb0 346 Pfam PF13505 Outer membrane protein beta-barrel domain 10 213 2.8E-22 T 14-10-2018 IPR027385 Outer membrane protein beta-barrel TSH58p_04790 bd37ed76701ac6dce101f592198abdb0 346 SUPERFAMILY SSF56925 23 218 4.97E-29 T 14-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel TSH58p_04790 bd37ed76701ac6dce101f592198abdb0 346 SUPERFAMILY SSF103088 227 343 4.19E-28 T 14-10-2018 IPR036737 OmpA-like domain superfamily TSH58p_12475 85239a6e4d5c91516a79a01557b990a5 314 SUPERFAMILY SSF54534 146 246 4.32E-34 T 14-10-2018 TSH58p_12475 85239a6e4d5c91516a79a01557b990a5 314 Gene3D G3DSA:3.10.50.40 148 271 4.4E-40 T 14-10-2018 TSH58p_12475 85239a6e4d5c91516a79a01557b990a5 314 SUPERFAMILY SSF109998 47 185 2.12E-17 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily TSH58p_12475 85239a6e4d5c91516a79a01557b990a5 314 Pfam PF13616 PPIC-type PPIASE domain 148 248 1.1E-28 T 14-10-2018 TSH58p_07110 a506a59e58baa09784aa1b40c67dc43b 121 Gene3D G3DSA:2.40.128.290 44 121 1.4E-39 T 14-10-2018 IPR038646 Atu4866-like superfamily TSH58p_07110 a506a59e58baa09784aa1b40c67dc43b 121 Pfam PF11512 Agrobacterium tumefaciens protein Atu4866 45 119 7.7E-42 T 14-10-2018 IPR020955 Uncharacterised protein family Atu4866 TSH58p_32035 25f4877d4bf6bcdfa3b2f49aafc912c9 637 Gene3D G3DSA:3.40.50.410 444 612 7.4E-18 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TSH58p_32035 25f4877d4bf6bcdfa3b2f49aafc912c9 637 SUPERFAMILY SSF53300 448 634 2.07E-24 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TSH58p_32035 25f4877d4bf6bcdfa3b2f49aafc912c9 637 Pfam PF13519 von Willebrand factor type A domain 450 563 5.8E-11 T 14-10-2018 IPR002035 von Willebrand factor, type A TSH58p_32035 25f4877d4bf6bcdfa3b2f49aafc912c9 637 SMART SM00327 447 630 2.6E-19 T 14-10-2018 IPR002035 von Willebrand factor, type A TSH58p_23585 3d5738f9ccd9965e17ec56256644ce60 237 Pfam PF01614 Bacterial transcriptional regulator 175 229 2.0E-6 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal TSH58p_23585 3d5738f9ccd9965e17ec56256644ce60 237 Pfam PF09339 IclR helix-turn-helix domain 18 67 1.1E-13 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TSH58p_23585 3d5738f9ccd9965e17ec56256644ce60 237 Gene3D G3DSA:3.30.450.40 171 237 8.4E-13 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_23585 3d5738f9ccd9965e17ec56256644ce60 237 SUPERFAMILY SSF46785 16 89 2.58E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_23585 3d5738f9ccd9965e17ec56256644ce60 237 SMART SM00346 16 105 8.9E-18 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TSH58p_23585 3d5738f9ccd9965e17ec56256644ce60 237 Gene3D G3DSA:1.10.10.10 1 76 4.5E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_23585 3d5738f9ccd9965e17ec56256644ce60 237 SUPERFAMILY SSF55781 74 233 7.19E-27 T 14-10-2018 TSH58p_23585 3d5738f9ccd9965e17ec56256644ce60 237 Gene3D G3DSA:3.30.450.40 84 166 3.4E-14 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_30320 ae3fdaa840cd1a06a787117d46f69649 237 SUPERFAMILY SSF51206 8 145 1.7E-21 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like TSH58p_30320 ae3fdaa840cd1a06a787117d46f69649 237 SMART SM00100 14 132 0.0094 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_30320 ae3fdaa840cd1a06a787117d46f69649 237 Gene3D G3DSA:2.60.120.10 2 135 1.4E-21 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_30320 ae3fdaa840cd1a06a787117d46f69649 237 Gene3D G3DSA:1.10.10.10 137 235 8.3E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_30320 ae3fdaa840cd1a06a787117d46f69649 237 Pfam PF13545 Crp-like helix-turn-helix domain 152 225 1.1E-15 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_30320 ae3fdaa840cd1a06a787117d46f69649 237 Pfam PF00027 Cyclic nucleotide-binding domain 33 119 2.1E-13 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_30320 ae3fdaa840cd1a06a787117d46f69649 237 SUPERFAMILY SSF46785 150 228 1.91E-7 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_10000 52fad55f5293cfd2e354d12dcc3aebfc 368 SMART SM00228 275 357 7.8E-17 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_10000 52fad55f5293cfd2e354d12dcc3aebfc 368 Pfam PF13180 PDZ domain 275 364 3.6E-15 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_10000 52fad55f5293cfd2e354d12dcc3aebfc 368 Gene3D G3DSA:2.40.10.120 47 269 3.3E-85 T 14-10-2018 TSH58p_10000 52fad55f5293cfd2e354d12dcc3aebfc 368 SUPERFAMILY SSF50156 233 357 7.92E-25 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 TSH58p_10000 52fad55f5293cfd2e354d12dcc3aebfc 368 Pfam PF13365 Trypsin-like peptidase domain 101 236 3.7E-33 T 14-10-2018 TSH58p_10000 52fad55f5293cfd2e354d12dcc3aebfc 368 SUPERFAMILY SSF50494 47 267 1.59E-65 T 14-10-2018 IPR009003 Peptidase S1, PA clan TSH58p_10000 52fad55f5293cfd2e354d12dcc3aebfc 368 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 50 366 1.1E-129 T 14-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 TSH58p_10000 52fad55f5293cfd2e354d12dcc3aebfc 368 PRINTS PR00834 HtrA/DegQ protease family signature 132 152 7.3E-55 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_10000 52fad55f5293cfd2e354d12dcc3aebfc 368 PRINTS PR00834 HtrA/DegQ protease family signature 207 224 7.3E-55 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_10000 52fad55f5293cfd2e354d12dcc3aebfc 368 PRINTS PR00834 HtrA/DegQ protease family signature 229 246 7.3E-55 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_10000 52fad55f5293cfd2e354d12dcc3aebfc 368 PRINTS PR00834 HtrA/DegQ protease family signature 315 327 7.3E-55 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_10000 52fad55f5293cfd2e354d12dcc3aebfc 368 PRINTS PR00834 HtrA/DegQ protease family signature 111 123 7.3E-55 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_10000 52fad55f5293cfd2e354d12dcc3aebfc 368 PRINTS PR00834 HtrA/DegQ protease family signature 172 196 7.3E-55 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_10000 52fad55f5293cfd2e354d12dcc3aebfc 368 Gene3D G3DSA:2.30.42.10 270 368 8.9E-27 T 14-10-2018 TSH58p_08580 f59435f82a582fd51c07c9bf3ef4b39f 191 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 185 6.4E-38 T 14-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 TSH58p_08580 f59435f82a582fd51c07c9bf3ef4b39f 191 Pfam PF03602 Conserved hypothetical protein 95 1 184 2.1E-44 T 14-10-2018 TSH58p_08580 f59435f82a582fd51c07c9bf3ef4b39f 191 PIRSF PIRSF004553 1 188 8.1E-45 T 14-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 TSH58p_08580 f59435f82a582fd51c07c9bf3ef4b39f 191 Gene3D G3DSA:3.40.50.150 1 187 5.9E-54 T 14-10-2018 TSH58p_08580 f59435f82a582fd51c07c9bf3ef4b39f 191 SUPERFAMILY SSF53335 1 185 4.15E-39 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_07795 bf0e377750cb33bda3a1a02c6fbc811b 625 Pfam PF07238 PilZ domain 520 604 1.7E-5 T 14-10-2018 IPR009875 PilZ domain GO:0035438 TSH58p_07795 bf0e377750cb33bda3a1a02c6fbc811b 625 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 340 480 1.3E-31 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_07795 bf0e377750cb33bda3a1a02c6fbc811b 625 Gene3D G3DSA:1.10.287.950 229 521 1.2E-54 T 14-10-2018 TSH58p_07795 bf0e377750cb33bda3a1a02c6fbc811b 625 SMART SM00304 168 221 1.5E-5 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_07795 bf0e377750cb33bda3a1a02c6fbc811b 625 SUPERFAMILY SSF58104 197 507 1.83E-59 T 14-10-2018 TSH58p_07795 bf0e377750cb33bda3a1a02c6fbc811b 625 Pfam PF00672 HAMP domain 169 214 3.0E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_07795 bf0e377750cb33bda3a1a02c6fbc811b 625 SMART SM00283 258 512 3.5E-44 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_07795 bf0e377750cb33bda3a1a02c6fbc811b 625 Gene3D G3DSA:1.20.1480.50 132 227 1.4E-14 T 14-10-2018 TSH58p_07795 bf0e377750cb33bda3a1a02c6fbc811b 625 SUPERFAMILY SSF141371 518 598 7.65E-6 T 14-10-2018 TSH58p_29525 92a0c415aa0d04fc9989eb6f9d315aa4 459 Pfam PF13649 Methyltransferase domain 298 387 1.4E-10 T 14-10-2018 TSH58p_29525 92a0c415aa0d04fc9989eb6f9d315aa4 459 Gene3D G3DSA:3.40.50.150 248 442 4.7E-24 T 14-10-2018 TSH58p_29525 92a0c415aa0d04fc9989eb6f9d315aa4 459 SUPERFAMILY SSF53335 251 439 1.78E-27 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_29525 92a0c415aa0d04fc9989eb6f9d315aa4 459 Pfam PF13429 Tetratricopeptide repeat 96 221 5.6E-10 T 14-10-2018 TSH58p_29525 92a0c415aa0d04fc9989eb6f9d315aa4 459 Gene3D G3DSA:1.25.40.10 22 163 5.1E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29525 92a0c415aa0d04fc9989eb6f9d315aa4 459 Gene3D G3DSA:1.25.40.10 165 243 2.3E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29525 92a0c415aa0d04fc9989eb6f9d315aa4 459 SMART SM00028 58 91 17.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29525 92a0c415aa0d04fc9989eb6f9d315aa4 459 SMART SM00028 194 227 38.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29525 92a0c415aa0d04fc9989eb6f9d315aa4 459 SMART SM00028 126 159 0.57 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29525 92a0c415aa0d04fc9989eb6f9d315aa4 459 SUPERFAMILY SSF48452 25 224 3.07E-24 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_23690 a8029b49aff7cbe64b5620f26a935bc4 268 Pfam PF12697 Alpha/beta hydrolase family 43 253 8.4E-18 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_23690 a8029b49aff7cbe64b5620f26a935bc4 268 SUPERFAMILY SSF53474 38 258 4.74E-28 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_23690 a8029b49aff7cbe64b5620f26a935bc4 268 Gene3D G3DSA:3.40.50.1820 31 262 2.8E-35 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_16480 8b484ef09c43cca014972cf0c2c65254 311 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 13 289 3.7E-66 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TSH58p_16480 8b484ef09c43cca014972cf0c2c65254 311 SUPERFAMILY SSF160240 212 290 6.02E-23 T 14-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 TSH58p_16480 8b484ef09c43cca014972cf0c2c65254 311 Pfam PF16916 Dimerisation domain of Zinc Transporter 212 289 2.2E-26 T 14-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain TSH58p_16480 8b484ef09c43cca014972cf0c2c65254 311 SUPERFAMILY SSF161111 7 209 3.66E-48 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TSH58p_16480 8b484ef09c43cca014972cf0c2c65254 311 Gene3D G3DSA:3.30.70.1350 209 291 1.3E-29 T 14-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 TSH58p_16480 8b484ef09c43cca014972cf0c2c65254 311 Gene3D G3DSA:1.20.1510.10 10 208 8.3E-51 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TSH58p_16480 8b484ef09c43cca014972cf0c2c65254 311 Pfam PF01545 Cation efflux family 15 208 3.9E-38 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TSH58p_06900 176aa5cb8c8213c3fb3a1ca2cf331e88 194 Pfam PF13302 Acetyltransferase (GNAT) domain 10 151 2.8E-31 T 14-10-2018 IPR000182 GNAT domain TSH58p_06900 176aa5cb8c8213c3fb3a1ca2cf331e88 194 SUPERFAMILY SSF55729 2 153 5.13E-39 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_06900 176aa5cb8c8213c3fb3a1ca2cf331e88 194 Gene3D G3DSA:3.40.630.30 2 163 2.9E-45 T 14-10-2018 TSH58p_05055 3dad51da2c30404ed0a3e88439696899 513 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 288 303 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 TSH58p_05055 3dad51da2c30404ed0a3e88439696899 513 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 415 424 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site TSH58p_05055 3dad51da2c30404ed0a3e88439696899 513 TIGRFAM TIGR04381 HTH_TypR: TyrR family helix-turn-helix domain 464 510 2.0E-22 T 14-10-2018 IPR030828 TyrR family, helix-turn-helix domain GO:0003677 TSH58p_05055 3dad51da2c30404ed0a3e88439696899 513 SUPERFAMILY SSF52540 201 444 4.14E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_05055 3dad51da2c30404ed0a3e88439696899 513 Pfam PF00989 PAS fold 80 136 4.0E-7 T 14-10-2018 IPR013767 PAS fold GO:0006355 TSH58p_05055 3dad51da2c30404ed0a3e88439696899 513 Gene3D G3DSA:3.30.450.20 81 185 2.2E-16 T 14-10-2018 TSH58p_05055 3dad51da2c30404ed0a3e88439696899 513 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 225 238 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 TSH58p_05055 3dad51da2c30404ed0a3e88439696899 513 Gene3D G3DSA:3.30.70.260 1 79 1.6E-16 T 14-10-2018 TSH58p_05055 3dad51da2c30404ed0a3e88439696899 513 SMART SM00382 221 366 7.6E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_05055 3dad51da2c30404ed0a3e88439696899 513 Gene3D G3DSA:1.10.10.60 457 510 6.7E-21 T 14-10-2018 TSH58p_05055 3dad51da2c30404ed0a3e88439696899 513 SUPERFAMILY SSF55785 80 175 1.48E-10 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_05055 3dad51da2c30404ed0a3e88439696899 513 SMART SM00091 79 146 5.9E-6 T 14-10-2018 IPR000014 PAS domain TSH58p_05055 3dad51da2c30404ed0a3e88439696899 513 SUPERFAMILY SSF46689 459 509 4.3E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_05055 3dad51da2c30404ed0a3e88439696899 513 Gene3D G3DSA:1.10.8.60 373 451 1.2E-21 T 14-10-2018 TSH58p_05055 3dad51da2c30404ed0a3e88439696899 513 Pfam PF00158 Sigma-54 interaction domain 201 368 2.8E-64 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 TSH58p_05055 3dad51da2c30404ed0a3e88439696899 513 Gene3D G3DSA:3.40.50.300 191 372 8.2E-64 T 14-10-2018 TSH58p_27675 30db65955859756c33c998d2eecd6eba 368 Pfam PF00753 Metallo-beta-lactamase superfamily 32 158 1.9E-10 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_27675 30db65955859756c33c998d2eecd6eba 368 SUPERFAMILY SSF56281 13 353 4.72E-44 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_27675 30db65955859756c33c998d2eecd6eba 368 SMART SM00849 24 203 1.0E-12 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_27675 30db65955859756c33c998d2eecd6eba 368 Gene3D G3DSA:3.60.15.10 11 212 2.2E-22 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_27675 30db65955859756c33c998d2eecd6eba 368 Gene3D G3DSA:3.40.50.10890 242 324 3.3E-6 T 14-10-2018 TSH58p_18985 0452fdaba56e5bb07dc721713ee42c4a 405 Gene3D G3DSA:3.30.420.40 1 199 1.8E-57 T 14-10-2018 TSH58p_18985 0452fdaba56e5bb07dc721713ee42c4a 405 Hamap MF_00020 Acetate kinase [ackA]. 1 397 157.816 T 14-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_18985 0452fdaba56e5bb07dc721713ee42c4a 405 Pfam PF00871 Acetokinase family 7 387 1.4E-105 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_18985 0452fdaba56e5bb07dc721713ee42c4a 405 PIRSF PIRSF000722 3 398 3.1E-135 T 14-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_18985 0452fdaba56e5bb07dc721713ee42c4a 405 SUPERFAMILY SSF53067 6 200 3.24E-56 T 14-10-2018 TSH58p_18985 0452fdaba56e5bb07dc721713ee42c4a 405 SUPERFAMILY SSF53067 164 394 1.96E-80 T 14-10-2018 TSH58p_18985 0452fdaba56e5bb07dc721713ee42c4a 405 Gene3D G3DSA:3.30.420.40 201 401 1.2E-72 T 14-10-2018 TSH58p_18985 0452fdaba56e5bb07dc721713ee42c4a 405 TIGRFAM TIGR00016 ackA: acetate kinase 6 391 5.0E-106 T 14-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_18985 0452fdaba56e5bb07dc721713ee42c4a 405 PRINTS PR00471 Acetate kinase family signature 207 228 7.1E-39 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_18985 0452fdaba56e5bb07dc721713ee42c4a 405 PRINTS PR00471 Acetate kinase family signature 323 339 7.1E-39 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_18985 0452fdaba56e5bb07dc721713ee42c4a 405 PRINTS PR00471 Acetate kinase family signature 301 314 7.1E-39 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_18985 0452fdaba56e5bb07dc721713ee42c4a 405 PRINTS PR00471 Acetate kinase family signature 7 18 7.1E-39 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_18985 0452fdaba56e5bb07dc721713ee42c4a 405 PRINTS PR00471 Acetate kinase family signature 178 191 7.1E-39 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_18985 0452fdaba56e5bb07dc721713ee42c4a 405 PRINTS PR00471 Acetate kinase family signature 375 387 7.1E-39 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_29230 fb1bf336731da6e8566cec486ccedac4 621 SUPERFAMILY SSF64518 5 621 1.24E-41 T 14-10-2018 TSH58p_29230 fb1bf336731da6e8566cec486ccedac4 621 Pfam PF00669 Bacterial flagellin N-terminal helical region 10 146 1.3E-15 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 TSH58p_29230 fb1bf336731da6e8566cec486ccedac4 621 Gene3D G3DSA:1.20.1330.10 49 224 1.9E-9 T 14-10-2018 TSH58p_29230 fb1bf336731da6e8566cec486ccedac4 621 Pfam PF00700 Bacterial flagellin C-terminal helical region 539 621 1.2E-4 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 TSH58p_03060 58b830a39cce804d3645997a6398f22f 225 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 59 215 6.6E-13 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain TSH58p_03060 58b830a39cce804d3645997a6398f22f 225 SUPERFAMILY SSF52266 39 222 1.83E-28 T 14-10-2018 TSH58p_03060 58b830a39cce804d3645997a6398f22f 225 Gene3D G3DSA:3.40.50.1110 33 223 2.4E-30 T 14-10-2018 IPR036514 SGNH hydrolase superfamily TSH58p_18830 7bca611a549738d1dcde9a4daa939e1f 357 Pfam PF01263 Aldose 1-epimerase 22 352 1.0E-74 T 14-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 TSH58p_18830 7bca611a549738d1dcde9a4daa939e1f 357 PIRSF PIRSF005096 5 357 6.5E-111 T 14-10-2018 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 TSH58p_18830 7bca611a549738d1dcde9a4daa939e1f 357 SUPERFAMILY SSF74650 11 354 1.19E-99 T 14-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 TSH58p_18830 7bca611a549738d1dcde9a4daa939e1f 357 Gene3D G3DSA:2.70.98.10 4 357 1.3E-105 T 14-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 TSH58p_19010 736f743c05a145c1b0843d046aeb85be 151 Pfam PF08808 RES domain 4 143 2.9E-19 T 14-10-2018 IPR014914 RES domain TSH58p_19010 736f743c05a145c1b0843d046aeb85be 151 SMART SM00953 13 136 3.9E-20 T 14-10-2018 IPR014914 RES domain TSH58p_30555 a661cff8a482fe0aff1898a8b383571b 97 Pfam PF00166 Chaperonin 10 Kd subunit 3 94 4.4E-35 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TSH58p_30555 a661cff8a482fe0aff1898a8b383571b 97 SUPERFAMILY SSF50129 1 95 1.79E-34 T 14-10-2018 IPR011032 GroES-like superfamily TSH58p_30555 a661cff8a482fe0aff1898a8b383571b 97 PRINTS PR00297 10kDa chaperonin signature 60 72 3.1E-32 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TSH58p_30555 a661cff8a482fe0aff1898a8b383571b 97 PRINTS PR00297 10kDa chaperonin signature 3 18 3.1E-32 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TSH58p_30555 a661cff8a482fe0aff1898a8b383571b 97 PRINTS PR00297 10kDa chaperonin signature 25 46 3.1E-32 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TSH58p_30555 a661cff8a482fe0aff1898a8b383571b 97 PRINTS PR00297 10kDa chaperonin signature 81 94 3.1E-32 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TSH58p_30555 a661cff8a482fe0aff1898a8b383571b 97 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 14-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 TSH58p_30555 a661cff8a482fe0aff1898a8b383571b 97 Gene3D G3DSA:2.30.33.40 1 96 2.4E-38 T 14-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 TSH58p_30555 a661cff8a482fe0aff1898a8b383571b 97 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 26.453 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TSH58p_30555 a661cff8a482fe0aff1898a8b383571b 97 SMART SM00883 2 94 3.2E-55 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TSH58p_16220 c54a361ce8ac913c0e2df58b26471256 309 PIRSF PIRSF038992 21 308 1.3E-64 T 14-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TSH58p_16220 c54a361ce8ac913c0e2df58b26471256 309 SMART SM01133 40 289 1.7E-46 T 14-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TSH58p_16220 c54a361ce8ac913c0e2df58b26471256 309 Pfam PF01791 DeoC/LacD family aldolase 41 289 4.0E-35 T 14-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TSH58p_16220 c54a361ce8ac913c0e2df58b26471256 309 Gene3D G3DSA:3.20.20.70 18 309 5.8E-80 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_16220 c54a361ce8ac913c0e2df58b26471256 309 SUPERFAMILY SSF51569 20 305 2.1E-65 T 14-10-2018 TSH58p_13820 38fb7dcb8c315a22a501d662004fd229 383 Gene3D G3DSA:3.90.550.10 27 241 1.2E-38 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_13820 38fb7dcb8c315a22a501d662004fd229 383 SUPERFAMILY SSF53448 44 298 1.33E-39 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_13820 38fb7dcb8c315a22a501d662004fd229 383 Pfam PF00535 Glycosyl transferase family 2 48 208 3.6E-32 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_15470 2adcd1181afdd80b145a8c4b114c348f 121 Pfam PF04347 Flagellar biosynthesis protein, FliO 25 79 5.0E-9 T 14-10-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 TSH58p_05420 9aed2d62e19440071d8bd8200cceb4af 284 Gene3D G3DSA:3.40.50.300 19 254 1.2E-62 T 14-10-2018 TSH58p_05420 9aed2d62e19440071d8bd8200cceb4af 284 SMART SM00382 52 232 8.8E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_05420 9aed2d62e19440071d8bd8200cceb4af 284 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_05420 9aed2d62e19440071d8bd8200cceb4af 284 SUPERFAMILY SSF52540 21 252 6.86E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_05420 9aed2d62e19440071d8bd8200cceb4af 284 Pfam PF00005 ABC transporter 44 182 6.4E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 SUPERFAMILY SSF56059 128 400 1.24E-104 T 14-10-2018 TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 SUPERFAMILY SSF52440 1 127 3.6E-46 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 SUPERFAMILY SSF52335 944 1079 1.24E-39 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 Gene3D G3DSA:3.30.470.20 120 402 2.2E-123 T 14-10-2018 TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1078 13.358 T 14-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 718 732 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 682 884 3.3E-37 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 1.5E-67 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 Gene3D G3DSA:3.30.470.20 674 944 9.4E-112 T 14-10-2018 TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 SMART SM01096 424 546 1.1E-68 T 14-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 Gene3D G3DSA:3.40.50.20 559 671 1.7E-46 T 14-10-2018 TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 Pfam PF02142 MGS-like domain 966 1050 4.4E-18 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 848 855 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 SUPERFAMILY SSF56059 682 942 1.01E-100 T 14-10-2018 TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 SMART SM00851 964 1050 6.9E-30 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 SUPERFAMILY SSF52440 561 684 7.77E-46 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1070 13.033 T 14-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 SUPERFAMILY SSF48108 395 549 1.57E-47 T 14-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 Gene3D G3DSA:3.40.50.1380 945 1080 9.8E-39 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 427 546 2.3E-40 T 14-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 Gene3D G3DSA:3.40.50.20 1 116 3.1E-47 T 14-10-2018 TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 379 397 3.8E-63 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 3.8E-63 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 3.8E-63 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 3.8E-63 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 3.8E-63 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 3.8E-63 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 3.8E-63 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 Gene3D G3DSA:1.10.1030.10 403 551 2.0E-43 T 14-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSH58p_08970 5c18f00028f4db520808885e6250afa1 1083 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1061 0.0 T 14-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSH58p_03350 37a7165f2e67e3a4aa64caa0f9779e91 279 SUPERFAMILY SSF55781 87 269 9.32E-47 T 14-10-2018 TSH58p_03350 37a7165f2e67e3a4aa64caa0f9779e91 279 SUPERFAMILY SSF46785 24 94 8.28E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_03350 37a7165f2e67e3a4aa64caa0f9779e91 279 SMART SM00346 23 110 3.2E-17 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TSH58p_03350 37a7165f2e67e3a4aa64caa0f9779e91 279 Pfam PF01614 Bacterial transcriptional regulator 139 265 9.0E-24 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal TSH58p_03350 37a7165f2e67e3a4aa64caa0f9779e91 279 Pfam PF09339 IclR helix-turn-helix domain 25 72 1.1E-12 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TSH58p_03350 37a7165f2e67e3a4aa64caa0f9779e91 279 Gene3D G3DSA:3.30.450.40 95 273 8.8E-54 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_03350 37a7165f2e67e3a4aa64caa0f9779e91 279 Gene3D G3DSA:1.10.10.10 21 94 1.8E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_21745 9450b42e3ac6a7f49616796a618f28bf 1040 Gene3D G3DSA:3.30.70.1430 40 800 0.0 T 14-10-2018 TSH58p_21745 9450b42e3ac6a7f49616796a618f28bf 1040 Gene3D G3DSA:3.30.70.1320 135 326 0.0 T 14-10-2018 TSH58p_21745 9450b42e3ac6a7f49616796a618f28bf 1040 SUPERFAMILY SSF82866 290 489 1.11E-47 T 14-10-2018 TSH58p_21745 9450b42e3ac6a7f49616796a618f28bf 1040 SUPERFAMILY SSF82866 789 1013 2.49E-45 T 14-10-2018 TSH58p_21745 9450b42e3ac6a7f49616796a618f28bf 1040 Gene3D G3DSA:3.30.70.1430 559 651 0.0 T 14-10-2018 TSH58p_21745 9450b42e3ac6a7f49616796a618f28bf 1040 SUPERFAMILY SSF82714 183 266 1.7E-16 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_21745 9450b42e3ac6a7f49616796a618f28bf 1040 Pfam PF00873 AcrB/AcrD/AcrF family 4 1011 0.0 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_21745 9450b42e3ac6a7f49616796a618f28bf 1040 SUPERFAMILY SSF82693 40 132 8.89E-23 T 14-10-2018 TSH58p_21745 9450b42e3ac6a7f49616796a618f28bf 1040 Gene3D G3DSA:1.20.1640.10 10 504 0.0 T 14-10-2018 TSH58p_21745 9450b42e3ac6a7f49616796a618f28bf 1040 Gene3D G3DSA:3.30.2090.10 704 792 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_21745 9450b42e3ac6a7f49616796a618f28bf 1040 SUPERFAMILY SSF82693 557 652 7.15E-14 T 14-10-2018 TSH58p_21745 9450b42e3ac6a7f49616796a618f28bf 1040 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 1.2E-73 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_21745 9450b42e3ac6a7f49616796a618f28bf 1040 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.2E-73 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_21745 9450b42e3ac6a7f49616796a618f28bf 1040 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 1.2E-73 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_21745 9450b42e3ac6a7f49616796a618f28bf 1040 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.2E-73 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_21745 9450b42e3ac6a7f49616796a618f28bf 1040 PRINTS PR00702 Acriflavin resistance protein family signature 544 561 1.2E-73 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_21745 9450b42e3ac6a7f49616796a618f28bf 1040 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 1.2E-73 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_21745 9450b42e3ac6a7f49616796a618f28bf 1040 PRINTS PR00702 Acriflavin resistance protein family signature 609 623 1.2E-73 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_21745 9450b42e3ac6a7f49616796a618f28bf 1040 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 1.2E-73 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_21745 9450b42e3ac6a7f49616796a618f28bf 1040 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 1.2E-73 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_21745 9450b42e3ac6a7f49616796a618f28bf 1040 SUPERFAMILY SSF82693 136 324 7.32E-24 T 14-10-2018 TSH58p_21745 9450b42e3ac6a7f49616796a618f28bf 1040 SUPERFAMILY SSF82714 705 791 2.62E-19 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_21745 9450b42e3ac6a7f49616796a618f28bf 1040 Gene3D G3DSA:3.30.2090.10 179 269 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_21745 9450b42e3ac6a7f49616796a618f28bf 1040 Gene3D G3DSA:1.20.1640.10 505 1008 0.0 T 14-10-2018 TSH58p_21745 9450b42e3ac6a7f49616796a618f28bf 1040 Gene3D G3DSA:3.30.70.1440 652 850 0.0 T 14-10-2018 TSH58p_31665 0899acc7ee5d54834976a7d67cf54e9c 260 Gene3D G3DSA:1.10.10.10 12 107 1.5E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_31665 0899acc7ee5d54834976a7d67cf54e9c 260 Pfam PF09339 IclR helix-turn-helix domain 39 71 3.2E-6 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TSH58p_31665 0899acc7ee5d54834976a7d67cf54e9c 260 SUPERFAMILY SSF46785 14 112 1.72E-9 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_27620 6c1ba570f15f0e9331966588e67176c1 968 SUPERFAMILY SSF55785 307 415 3.32E-8 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_27620 6c1ba570f15f0e9331966588e67176c1 968 Pfam PF00512 His Kinase A (phospho-acceptor) domain 577 642 1.9E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_27620 6c1ba570f15f0e9331966588e67176c1 968 SMART SM00448 830 944 2.5E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_27620 6c1ba570f15f0e9331966588e67176c1 968 PRINTS PR00344 Bacterial sensor protein C-terminal signature 733 747 1.6E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_27620 6c1ba570f15f0e9331966588e67176c1 968 PRINTS PR00344 Bacterial sensor protein C-terminal signature 751 761 1.6E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_27620 6c1ba570f15f0e9331966588e67176c1 968 PRINTS PR00344 Bacterial sensor protein C-terminal signature 792 805 1.6E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_27620 6c1ba570f15f0e9331966588e67176c1 968 PRINTS PR00344 Bacterial sensor protein C-terminal signature 768 786 1.6E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_27620 6c1ba570f15f0e9331966588e67176c1 968 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 688 807 4.8E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_27620 6c1ba570f15f0e9331966588e67176c1 968 SUPERFAMILY SSF55874 631 814 1.3E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_27620 6c1ba570f15f0e9331966588e67176c1 968 SUPERFAMILY SSF52172 830 952 3.27E-21 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_27620 6c1ba570f15f0e9331966588e67176c1 968 SMART SM00091 315 380 3.3 T 14-10-2018 IPR000014 PAS domain TSH58p_27620 6c1ba570f15f0e9331966588e67176c1 968 SMART SM00091 438 508 14.0 T 14-10-2018 IPR000014 PAS domain TSH58p_27620 6c1ba570f15f0e9331966588e67176c1 968 SUPERFAMILY SSF55785 425 554 2.27E-14 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_27620 6c1ba570f15f0e9331966588e67176c1 968 Gene3D G3DSA:3.30.450.20 27 173 2.1E-11 T 14-10-2018 TSH58p_27620 6c1ba570f15f0e9331966588e67176c1 968 SUPERFAMILY SSF47384 560 642 3.73E-17 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_27620 6c1ba570f15f0e9331966588e67176c1 968 Gene3D G3DSA:3.30.450.20 312 418 3.5E-19 T 14-10-2018 TSH58p_27620 6c1ba570f15f0e9331966588e67176c1 968 Gene3D G3DSA:3.30.565.10 644 811 2.0E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_27620 6c1ba570f15f0e9331966588e67176c1 968 Gene3D G3DSA:3.30.450.20 429 567 2.4E-22 T 14-10-2018 TSH58p_27620 6c1ba570f15f0e9331966588e67176c1 968 SMART SM00388 577 642 5.5E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_27620 6c1ba570f15f0e9331966588e67176c1 968 Gene3D G3DSA:1.10.287.130 568 643 2.0E-16 T 14-10-2018 TSH58p_27620 6c1ba570f15f0e9331966588e67176c1 968 Pfam PF08448 PAS fold 444 558 4.3E-10 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_27620 6c1ba570f15f0e9331966588e67176c1 968 Pfam PF08448 PAS fold 321 421 1.9E-9 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_27620 6c1ba570f15f0e9331966588e67176c1 968 Pfam PF00072 Response regulator receiver domain 833 944 3.1E-10 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_27620 6c1ba570f15f0e9331966588e67176c1 968 SMART SM00387 687 808 4.3E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_27620 6c1ba570f15f0e9331966588e67176c1 968 Gene3D G3DSA:3.40.50.2300 823 960 7.0E-22 T 14-10-2018 TSH58p_30545 7734f3e107265ffa5c13ce980006d0aa 290 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 215 249 6.2E-7 T 14-10-2018 IPR001451 Hexapeptide repeat TSH58p_30545 7734f3e107265ffa5c13ce980006d0aa 290 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 170 206 1.3E-4 T 14-10-2018 IPR001451 Hexapeptide repeat TSH58p_30545 7734f3e107265ffa5c13ce980006d0aa 290 SUPERFAMILY SSF51161 28 271 3.05E-62 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily TSH58p_30545 7734f3e107265ffa5c13ce980006d0aa 290 Gene3D G3DSA:1.10.3130.10 18 164 1.8E-52 T 14-10-2018 TSH58p_30545 7734f3e107265ffa5c13ce980006d0aa 290 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 105 264 3.4E-71 T 14-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 TSH58p_30545 7734f3e107265ffa5c13ce980006d0aa 290 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 224 252 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 TSH58p_30545 7734f3e107265ffa5c13ce980006d0aa 290 SMART SM00971 31 135 1.9E-45 T 14-10-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 TSH58p_30545 7734f3e107265ffa5c13ce980006d0aa 290 Pfam PF06426 Serine acetyltransferase, N-terminal 31 134 1.6E-34 T 14-10-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 TSH58p_30545 7734f3e107265ffa5c13ce980006d0aa 290 Gene3D G3DSA:2.160.10.10 165 283 1.9E-36 T 14-10-2018 TSH58p_29315 3f7cda76c5fdec77a33e0688ae18ac83 177 SMART SM00347 55 156 6.9E-14 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_29315 3f7cda76c5fdec77a33e0688ae18ac83 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 97 112 2.6E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_29315 3f7cda76c5fdec77a33e0688ae18ac83 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 146 166 2.6E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_29315 3f7cda76c5fdec77a33e0688ae18ac83 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 96 2.6E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_29315 3f7cda76c5fdec77a33e0688ae18ac83 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 132 2.6E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_29315 3f7cda76c5fdec77a33e0688ae18ac83 177 Pfam PF12802 MarR family 63 119 1.7E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_29315 3f7cda76c5fdec77a33e0688ae18ac83 177 SUPERFAMILY SSF46785 33 169 9.1E-29 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_29315 3f7cda76c5fdec77a33e0688ae18ac83 177 Gene3D G3DSA:1.10.10.10 22 171 1.5E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_04520 109404d3e558853bd3f46748ed91e46b 210 Hamap MF_00165 Thymidylate kinase [tmk]. 5 207 29.529 T 14-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TSH58p_04520 109404d3e558853bd3f46748ed91e46b 210 Gene3D G3DSA:3.40.50.300 1 208 9.3E-65 T 14-10-2018 TSH58p_04520 109404d3e558853bd3f46748ed91e46b 210 SUPERFAMILY SSF52540 1 207 5.95E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_04520 109404d3e558853bd3f46748ed91e46b 210 ProSitePatterns PS01331 Thymidylate kinase signature. 94 106 - T 14-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TSH58p_04520 109404d3e558853bd3f46748ed91e46b 210 Pfam PF02223 Thymidylate kinase 9 199 8.8E-49 T 14-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 TSH58p_04520 109404d3e558853bd3f46748ed91e46b 210 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 1 199 1.5E-50 T 14-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TSH58p_19575 1c1139f0e12f2a218ed46b99195eff59 226 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_19575 1c1139f0e12f2a218ed46b99195eff59 226 Gene3D G3DSA:3.40.50.12740 4 214 9.9E-42 T 14-10-2018 TSH58p_19575 1c1139f0e12f2a218ed46b99195eff59 226 SUPERFAMILY SSF46894 150 214 2.89E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_19575 1c1139f0e12f2a218ed46b99195eff59 226 SUPERFAMILY SSF52172 1 121 4.25E-11 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_19575 1c1139f0e12f2a218ed46b99195eff59 226 Pfam PF00072 Response regulator receiver domain 6 117 3.7E-8 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_19575 1c1139f0e12f2a218ed46b99195eff59 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 8.9E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_19575 1c1139f0e12f2a218ed46b99195eff59 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 8.9E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_19575 1c1139f0e12f2a218ed46b99195eff59 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 8.9E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_19575 1c1139f0e12f2a218ed46b99195eff59 226 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 4.6E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_19575 1c1139f0e12f2a218ed46b99195eff59 226 SMART SM00421 152 209 6.5E-23 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_27170 cfdbf5fa0c4f800e742552f95a2006fe 680 SUPERFAMILY SSF55785 293 414 8.9E-23 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_27170 cfdbf5fa0c4f800e742552f95a2006fe 680 SMART SM00086 374 416 0.0021 T 14-10-2018 IPR001610 PAC motif TSH58p_27170 cfdbf5fa0c4f800e742552f95a2006fe 680 SUPERFAMILY SSF55874 487 661 1.7E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_27170 cfdbf5fa0c4f800e742552f95a2006fe 680 SMART SM00091 301 367 2.1E-5 T 14-10-2018 IPR000014 PAS domain TSH58p_27170 cfdbf5fa0c4f800e742552f95a2006fe 680 Pfam PF17159 Membrane-associated sensor domain 41 263 1.8E-73 T 14-10-2018 IPR033425 Membrane-associated sensor domain MASE3 TSH58p_27170 cfdbf5fa0c4f800e742552f95a2006fe 680 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 541 658 9.1E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_27170 cfdbf5fa0c4f800e742552f95a2006fe 680 SMART SM00388 431 497 3.4E-6 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_27170 cfdbf5fa0c4f800e742552f95a2006fe 680 PRINTS PR00344 Bacterial sensor protein C-terminal signature 589 603 8.3E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_27170 cfdbf5fa0c4f800e742552f95a2006fe 680 PRINTS PR00344 Bacterial sensor protein C-terminal signature 607 617 8.3E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_27170 cfdbf5fa0c4f800e742552f95a2006fe 680 PRINTS PR00344 Bacterial sensor protein C-terminal signature 620 638 8.3E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_27170 cfdbf5fa0c4f800e742552f95a2006fe 680 PRINTS PR00344 Bacterial sensor protein C-terminal signature 644 657 8.3E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_27170 cfdbf5fa0c4f800e742552f95a2006fe 680 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 297 422 9.6E-17 T 14-10-2018 IPR000014 PAS domain TSH58p_27170 cfdbf5fa0c4f800e742552f95a2006fe 680 Pfam PF00512 His Kinase A (phospho-acceptor) domain 432 495 2.5E-7 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_27170 cfdbf5fa0c4f800e742552f95a2006fe 680 Gene3D G3DSA:3.30.565.10 501 661 4.7E-43 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_27170 cfdbf5fa0c4f800e742552f95a2006fe 680 Gene3D G3DSA:3.30.450.20 288 426 3.9E-21 T 14-10-2018 TSH58p_27170 cfdbf5fa0c4f800e742552f95a2006fe 680 SMART SM00387 538 660 4.3E-30 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_27170 cfdbf5fa0c4f800e742552f95a2006fe 680 SUPERFAMILY SSF47384 422 495 4.9E-9 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_27170 cfdbf5fa0c4f800e742552f95a2006fe 680 Pfam PF08448 PAS fold 309 418 2.2E-8 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_27170 cfdbf5fa0c4f800e742552f95a2006fe 680 Gene3D G3DSA:1.10.287.130 427 495 4.8E-15 T 14-10-2018 TSH58p_06075 e05621300d54230507d72e2bb65ba1f7 531 Gene3D G3DSA:3.40.50.10890 225 400 2.6E-131 T 14-10-2018 TSH58p_06075 e05621300d54230507d72e2bb65ba1f7 531 SUPERFAMILY SSF56281 3 449 8.26E-116 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_06075 e05621300d54230507d72e2bb65ba1f7 531 SMART SM00849 15 245 3.5E-23 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_06075 e05621300d54230507d72e2bb65ba1f7 531 Pfam PF10996 Beta-Casp domain 257 372 1.4E-26 T 14-10-2018 IPR022712 Beta-Casp domain TSH58p_06075 e05621300d54230507d72e2bb65ba1f7 531 Pfam PF00753 Metallo-beta-lactamase superfamily 13 201 2.1E-15 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_06075 e05621300d54230507d72e2bb65ba1f7 531 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 388 446 2.6E-11 T 14-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain TSH58p_06075 e05621300d54230507d72e2bb65ba1f7 531 SMART SM01027 257 374 6.8E-49 T 14-10-2018 IPR022712 Beta-Casp domain TSH58p_06075 e05621300d54230507d72e2bb65ba1f7 531 Gene3D G3DSA:3.60.15.10 8 434 2.6E-131 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_30530 cce4bb5452c894bbcfebe5e33c6255b6 199 SMART SM00530 24 79 1.2E-15 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_30530 cce4bb5452c894bbcfebe5e33c6255b6 199 SUPERFAMILY SSF51182 64 197 6.68E-16 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_30530 cce4bb5452c894bbcfebe5e33c6255b6 199 SUPERFAMILY SSF47413 15 83 3.75E-18 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_30530 cce4bb5452c894bbcfebe5e33c6255b6 199 Pfam PF01381 Helix-turn-helix 25 78 3.2E-16 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_30530 cce4bb5452c894bbcfebe5e33c6255b6 199 Pfam PF07883 Cupin domain 129 193 7.3E-7 T 14-10-2018 IPR013096 Cupin 2, conserved barrel TSH58p_30530 cce4bb5452c894bbcfebe5e33c6255b6 199 Gene3D G3DSA:2.60.120.10 106 198 8.4E-11 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_30530 cce4bb5452c894bbcfebe5e33c6255b6 199 Gene3D G3DSA:1.10.260.40 12 85 1.1E-19 T 14-10-2018 TSH58p_27965 105a44f30038d1ff461addd497ee5fa0 839 PRINTS PR00344 Bacterial sensor protein C-terminal signature 741 755 2.0E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_27965 105a44f30038d1ff461addd497ee5fa0 839 PRINTS PR00344 Bacterial sensor protein C-terminal signature 772 790 2.0E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_27965 105a44f30038d1ff461addd497ee5fa0 839 PRINTS PR00344 Bacterial sensor protein C-terminal signature 797 810 2.0E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_27965 105a44f30038d1ff461addd497ee5fa0 839 PRINTS PR00344 Bacterial sensor protein C-terminal signature 759 769 2.0E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_27965 105a44f30038d1ff461addd497ee5fa0 839 SMART SM00387 695 813 2.4E-28 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_27965 105a44f30038d1ff461addd497ee5fa0 839 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 419 539 2.0E-7 T 14-10-2018 IPR000014 PAS domain TSH58p_27965 105a44f30038d1ff461addd497ee5fa0 839 Gene3D G3DSA:3.30.565.10 655 816 6.4E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_27965 105a44f30038d1ff461addd497ee5fa0 839 Gene3D G3DSA:1.10.287.130 550 647 7.6E-16 T 14-10-2018 TSH58p_27965 105a44f30038d1ff461addd497ee5fa0 839 SUPERFAMILY SSF55785 410 531 2.27E-11 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_27965 105a44f30038d1ff461addd497ee5fa0 839 SUPERFAMILY SSF55874 654 811 4.98E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_27965 105a44f30038d1ff461addd497ee5fa0 839 Gene3D G3DSA:3.30.450.20 418 549 9.5E-13 T 14-10-2018 TSH58p_27965 105a44f30038d1ff461addd497ee5fa0 839 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 698 812 3.7E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_15670 aff1ae858d23c5e59298a63e601ada80 313 SUPERFAMILY SSF53335 20 294 2.24E-49 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_15670 aff1ae858d23c5e59298a63e601ada80 313 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 19 297 3.1E-65 T 14-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 TSH58p_15670 aff1ae858d23c5e59298a63e601ada80 313 Gene3D G3DSA:3.40.50.150 108 286 1.8E-46 T 14-10-2018 TSH58p_15670 aff1ae858d23c5e59298a63e601ada80 313 PIRSF PIRSF037167 5 313 3.2E-118 T 14-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 TSH58p_15670 aff1ae858d23c5e59298a63e601ada80 313 Hamap MF_02125 50S ribosomal protein L3 glutamine methyltransferase [prmB]. 10 311 48.97 T 14-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 TSH58p_15670 aff1ae858d23c5e59298a63e601ada80 313 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 17 306 2.5E-118 T 14-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 TSH58p_15670 aff1ae858d23c5e59298a63e601ada80 313 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 215 221 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TSH58p_15670 aff1ae858d23c5e59298a63e601ada80 313 Pfam PF05175 Methyltransferase small domain 144 226 7.8E-19 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 TSH58p_09180 dfd5ac251bd34f7c6e5505d6e31af1f6 175 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 7 175 30.079 T 14-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TSH58p_09180 dfd5ac251bd34f7c6e5505d6e31af1f6 175 ProSitePatterns PS00938 Initiation factor 3 signature. 65 78 - T 14-10-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 TSH58p_09180 dfd5ac251bd34f7c6e5505d6e31af1f6 175 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 14 175 8.4E-69 T 14-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TSH58p_09180 dfd5ac251bd34f7c6e5505d6e31af1f6 175 Gene3D G3DSA:3.10.20.80 9 82 5.8E-31 T 14-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TSH58p_09180 dfd5ac251bd34f7c6e5505d6e31af1f6 175 SUPERFAMILY SSF54364 11 85 1.44E-28 T 14-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TSH58p_09180 dfd5ac251bd34f7c6e5505d6e31af1f6 175 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 90 174 1.1E-40 T 14-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 TSH58p_09180 dfd5ac251bd34f7c6e5505d6e31af1f6 175 SUPERFAMILY SSF55200 90 174 3.4E-35 T 14-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 TSH58p_09180 dfd5ac251bd34f7c6e5505d6e31af1f6 175 Gene3D G3DSA:3.30.110.10 83 175 1.7E-40 T 14-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 TSH58p_09180 dfd5ac251bd34f7c6e5505d6e31af1f6 175 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 14 83 4.6E-31 T 14-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TSH58p_28095 faacc1e662176467ee04558de0a3c7de 563 SMART SM00283 303 557 6.0E-47 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_28095 faacc1e662176467ee04558de0a3c7de 563 Pfam PF00672 HAMP domain 216 264 2.2E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_28095 faacc1e662176467ee04558de0a3c7de 563 SUPERFAMILY SSF58104 244 556 6.28E-63 T 14-10-2018 TSH58p_28095 faacc1e662176467ee04558de0a3c7de 563 Gene3D G3DSA:1.10.287.950 272 557 7.3E-56 T 14-10-2018 TSH58p_28095 faacc1e662176467ee04558de0a3c7de 563 Gene3D G3DSA:1.20.1480.50 174 271 5.1E-16 T 14-10-2018 TSH58p_28095 faacc1e662176467ee04558de0a3c7de 563 SMART SM00304 214 267 7.5E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_28095 faacc1e662176467ee04558de0a3c7de 563 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 367 527 8.7E-35 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_28095 faacc1e662176467ee04558de0a3c7de 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 430 459 2.7E-21 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_28095 faacc1e662176467ee04558de0a3c7de 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 8 33 2.7E-21 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_28095 faacc1e662176467ee04558de0a3c7de 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 478 507 2.7E-21 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_28095 faacc1e662176467ee04558de0a3c7de 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 401 428 2.7E-21 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_15105 1c83abb3a186d522bbdea2dd67bca07d 144 Gene3D G3DSA:1.10.10.2720 73 144 2.0E-27 T 14-10-2018 TSH58p_15105 1c83abb3a186d522bbdea2dd67bca07d 144 Gene3D G3DSA:3.30.1550.10 2 72 5.5E-35 T 14-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily TSH58p_15105 1c83abb3a186d522bbdea2dd67bca07d 144 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 5.9E-30 T 14-10-2018 IPR020784 Ribosomal protein L11, N-terminal TSH58p_15105 1c83abb3a186d522bbdea2dd67bca07d 144 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 141 3.4E-23 T 14-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 TSH58p_15105 1c83abb3a186d522bbdea2dd67bca07d 144 SUPERFAMILY SSF54747 3 73 5.1E-31 T 14-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily TSH58p_15105 1c83abb3a186d522bbdea2dd67bca07d 144 SMART SM00649 9 142 6.4E-78 T 14-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 TSH58p_15105 1c83abb3a186d522bbdea2dd67bca07d 144 SUPERFAMILY SSF46906 68 141 3.01E-23 T 14-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily TSH58p_15105 1c83abb3a186d522bbdea2dd67bca07d 144 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 143 30.281 T 14-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 TSH58p_15105 1c83abb3a186d522bbdea2dd67bca07d 144 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 142 4.5E-63 T 14-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_15105 1c83abb3a186d522bbdea2dd67bca07d 144 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 74 2.0E-13 T 14-10-2018 TSH58p_11860 f77ff3b1bbb82c9f277aa943b6359dbe 110 Gene3D G3DSA:3.30.70.20 2 100 3.1E-31 T 14-10-2018 TSH58p_11860 f77ff3b1bbb82c9f277aa943b6359dbe 110 Pfam PF11953 Domain of unknown function (DUF3470) 64 105 7.5E-20 T 14-10-2018 IPR022569 Ferredoxin, C-terminal TSH58p_11860 f77ff3b1bbb82c9f277aa943b6359dbe 110 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_11860 f77ff3b1bbb82c9f277aa943b6359dbe 110 SUPERFAMILY SSF54862 2 103 6.44E-24 T 14-10-2018 TSH58p_11860 f77ff3b1bbb82c9f277aa943b6359dbe 110 PRINTS PR00354 7Fe ferredoxin signature 9 19 5.2E-19 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TSH58p_11860 f77ff3b1bbb82c9f277aa943b6359dbe 110 PRINTS PR00354 7Fe ferredoxin signature 35 52 5.2E-19 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TSH58p_11860 f77ff3b1bbb82c9f277aa943b6359dbe 110 PRINTS PR00354 7Fe ferredoxin signature 19 29 5.2E-19 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TSH58p_11860 f77ff3b1bbb82c9f277aa943b6359dbe 110 Pfam PF00037 4Fe-4S binding domain 34 55 8.0E-7 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_08750 b03196772e1a20920ed28fa7965c7e25 79 PIRSF PIRSF003113 1 79 6.5E-20 T 14-10-2018 IPR002634 BolA protein TSH58p_08750 b03196772e1a20920ed28fa7965c7e25 79 SUPERFAMILY SSF82657 1 77 1.31E-25 T 14-10-2018 IPR036065 BolA-like superfamily TSH58p_08750 b03196772e1a20920ed28fa7965c7e25 79 Gene3D G3DSA:3.30.300.90 3 76 1.1E-28 T 14-10-2018 TSH58p_08750 b03196772e1a20920ed28fa7965c7e25 79 Pfam PF01722 BolA-like protein 27 77 4.1E-15 T 14-10-2018 IPR002634 BolA protein TSH58p_30965 a21bb4d7280df1de24fbe461f3c1205c 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 1.3E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_30965 a21bb4d7280df1de24fbe461f3c1205c 312 SUPERFAMILY SSF46785 2 85 3.05E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_30965 a21bb4d7280df1de24fbe461f3c1205c 312 Pfam PF03466 LysR substrate binding domain 93 293 4.6E-31 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_30965 a21bb4d7280df1de24fbe461f3c1205c 312 Gene3D G3DSA:1.10.10.10 4 93 6.9E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_30965 a21bb4d7280df1de24fbe461f3c1205c 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 6.9E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_30965 a21bb4d7280df1de24fbe461f3c1205c 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 6.9E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_30965 a21bb4d7280df1de24fbe461f3c1205c 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 6.9E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_30965 a21bb4d7280df1de24fbe461f3c1205c 312 Gene3D G3DSA:3.40.190.10 164 264 2.0E-49 T 14-10-2018 TSH58p_30965 a21bb4d7280df1de24fbe461f3c1205c 312 Gene3D G3DSA:3.40.190.10 103 290 2.0E-49 T 14-10-2018 TSH58p_30965 a21bb4d7280df1de24fbe461f3c1205c 312 SUPERFAMILY SSF53850 94 295 3.98E-32 T 14-10-2018 TSH58p_23080 961ff7e0fa27694dd55bfa682c153b69 368 SUPERFAMILY SSF54506 178 356 7.85E-54 T 14-10-2018 TSH58p_23080 961ff7e0fa27694dd55bfa682c153b69 368 Gene3D G3DSA:3.10.310.10 173 341 4.2E-119 T 14-10-2018 TSH58p_23080 961ff7e0fa27694dd55bfa682c153b69 368 Pfam PF04303 PrpF protein 8 356 2.8E-130 T 14-10-2018 IPR007400 PrpF protein TSH58p_23080 961ff7e0fa27694dd55bfa682c153b69 368 SUPERFAMILY SSF54506 6 174 5.73E-64 T 14-10-2018 TSH58p_23080 961ff7e0fa27694dd55bfa682c153b69 368 Gene3D G3DSA:3.10.310.10 11 355 4.2E-119 T 14-10-2018 TSH58p_28245 52d44531216ca91cd41b5f545a80b970 410 Pfam PF07690 Major Facilitator Superfamily 6 282 1.7E-23 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_28245 52d44531216ca91cd41b5f545a80b970 410 ProSitePatterns PS00216 Sugar transport proteins signature 1. 266 282 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TSH58p_28245 52d44531216ca91cd41b5f545a80b970 410 SUPERFAMILY SSF103473 5 391 4.19E-43 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_28245 52d44531216ca91cd41b5f545a80b970 410 Gene3D G3DSA:1.20.1250.20 211 409 2.1E-22 T 14-10-2018 TSH58p_28245 52d44531216ca91cd41b5f545a80b970 410 Gene3D G3DSA:1.20.1250.20 3 179 9.8E-15 T 14-10-2018 TSH58p_09020 f1a24e86ec27de68516281f6ae79033d 171 SMART SM01049 47 122 2.7E-6 T 14-10-2018 IPR033480 Single Cache domain 2 TSH58p_09020 f1a24e86ec27de68516281f6ae79033d 171 Pfam PF17200 Single Cache domain 2 79 170 1.3E-14 T 14-10-2018 IPR033480 Single Cache domain 2 TSH58p_09020 f1a24e86ec27de68516281f6ae79033d 171 Gene3D G3DSA:3.30.450.20 42 171 1.4E-20 T 14-10-2018 TSH58p_13070 27856983fd3acd383196d25327b88675 278 Pfam PF01061 ABC-2 type transporter 42 233 1.8E-9 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TSH58p_13070 27856983fd3acd383196d25327b88675 278 PRINTS PR00164 ABC-2 type transport system membrane protein signature 152 176 8.2E-5 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSH58p_13070 27856983fd3acd383196d25327b88675 278 PRINTS PR00164 ABC-2 type transport system membrane protein signature 190 209 8.2E-5 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSH58p_13070 27856983fd3acd383196d25327b88675 278 PRINTS PR00164 ABC-2 type transport system membrane protein signature 210 229 8.2E-5 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSH58p_04225 ac524f091feeeff572097bb761fd863a 126 Pfam PF08905 Domain of unknown function (DUF1850) 23 108 3.8E-28 T 14-10-2018 IPR015001 Protein of unknown function DUF1850 TSH58p_20760 449b51f8b9cec1a68cdedd72caf29032 418 Pfam PF06537 Di-haem oxidoreductase, putative peroxidase 88 416 6.5E-83 T 14-10-2018 IPR010538 Di-haem oxidoreductase, putative peroxidase TSH58p_20760 449b51f8b9cec1a68cdedd72caf29032 418 Pfam PF06537 Di-haem oxidoreductase, putative peroxidase 26 77 3.2E-7 T 14-10-2018 IPR010538 Di-haem oxidoreductase, putative peroxidase TSH58p_20760 449b51f8b9cec1a68cdedd72caf29032 418 SUPERFAMILY SSF46626 273 418 1.28E-17 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_20760 449b51f8b9cec1a68cdedd72caf29032 418 PIRSF PIRSF028099 17 418 1.6E-128 T 14-10-2018 IPR010538 Di-haem oxidoreductase, putative peroxidase TSH58p_32475 ef03f02cfe094018c640f40d1fb58241 380 SUPERFAMILY SSF111369 47 292 1.27E-62 T 14-10-2018 TSH58p_32475 ef03f02cfe094018c640f40d1fb58241 380 Gene3D G3DSA:2.40.420.20 279 369 3.6E-21 T 14-10-2018 TSH58p_32475 ef03f02cfe094018c640f40d1fb58241 380 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 62 287 1.1E-12 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain TSH58p_32475 ef03f02cfe094018c640f40d1fb58241 380 Gene3D G3DSA:1.10.287.470 94 167 4.2E-76 T 14-10-2018 TSH58p_32475 ef03f02cfe094018c640f40d1fb58241 380 Gene3D G3DSA:2.40.50.100 59 202 4.2E-76 T 14-10-2018 TSH58p_32475 ef03f02cfe094018c640f40d1fb58241 380 Gene3D G3DSA:2.40.30.170 53 278 4.2E-76 T 14-10-2018 TSH58p_32475 ef03f02cfe094018c640f40d1fb58241 380 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 35 368 1.7E-84 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 TSH58p_29680 df043cac15be62650ff84ecbb5a64435 136 PRINTS PR00332 Histidine triad family signature 6 22 1.8E-11 T 14-10-2018 IPR001310 Histidine triad (HIT) protein TSH58p_29680 df043cac15be62650ff84ecbb5a64435 136 PRINTS PR00332 Histidine triad family signature 94 104 1.8E-11 T 14-10-2018 IPR001310 Histidine triad (HIT) protein TSH58p_29680 df043cac15be62650ff84ecbb5a64435 136 PRINTS PR00332 Histidine triad family signature 27 45 1.8E-11 T 14-10-2018 IPR001310 Histidine triad (HIT) protein TSH58p_29680 df043cac15be62650ff84ecbb5a64435 136 SUPERFAMILY SSF54197 5 133 3.09E-36 T 14-10-2018 IPR036265 HIT-like superfamily TSH58p_29680 df043cac15be62650ff84ecbb5a64435 136 Pfam PF01230 HIT domain 13 108 2.3E-22 T 14-10-2018 IPR001310 Histidine triad (HIT) protein TSH58p_29680 df043cac15be62650ff84ecbb5a64435 136 Gene3D G3DSA:3.30.428.10 1 136 1.4E-38 T 14-10-2018 IPR036265 HIT-like superfamily TSH58p_18845 c3a137c1ca0ac7e34e0083992a098657 255 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 35 248 8.5E-29 T 14-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 TSH58p_18845 c3a137c1ca0ac7e34e0083992a098657 255 Gene3D G3DSA:3.40.190.10 106 214 4.4E-44 T 14-10-2018 TSH58p_18845 c3a137c1ca0ac7e34e0083992a098657 255 Gene3D G3DSA:3.40.190.10 36 249 4.4E-44 T 14-10-2018 TSH58p_18845 c3a137c1ca0ac7e34e0083992a098657 255 Pfam PF13531 Bacterial extracellular solute-binding protein 30 249 3.3E-49 T 14-10-2018 TSH58p_18845 c3a137c1ca0ac7e34e0083992a098657 255 SUPERFAMILY SSF53850 27 251 2.97E-51 T 14-10-2018 TSH58p_18845 c3a137c1ca0ac7e34e0083992a098657 255 PIRSF PIRSF004846 1 253 2.6E-49 T 14-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 TSH58p_15725 03048dd444b416d5eed1c256d183b318 783 Pfam PF13432 Tetratricopeptide repeat 28 81 7.0E-4 T 14-10-2018 TSH58p_15725 03048dd444b416d5eed1c256d183b318 783 Pfam PF13432 Tetratricopeptide repeat 89 149 4.3E-4 T 14-10-2018 TSH58p_15725 03048dd444b416d5eed1c256d183b318 783 Pfam PF13432 Tetratricopeptide repeat 190 252 4.3E-7 T 14-10-2018 TSH58p_15725 03048dd444b416d5eed1c256d183b318 783 SMART SM00028 15 48 23.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_15725 03048dd444b416d5eed1c256d183b318 783 SMART SM00028 49 82 400.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_15725 03048dd444b416d5eed1c256d183b318 783 SMART SM00028 286 319 320.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_15725 03048dd444b416d5eed1c256d183b318 783 SMART SM00028 219 252 4.2E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_15725 03048dd444b416d5eed1c256d183b318 783 SMART SM00028 83 116 0.061 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_15725 03048dd444b416d5eed1c256d183b318 783 SMART SM00028 151 184 0.37 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_15725 03048dd444b416d5eed1c256d183b318 783 SMART SM00028 185 218 17.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_15725 03048dd444b416d5eed1c256d183b318 783 Gene3D G3DSA:1.25.40.10 16 130 7.0E-22 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_15725 03048dd444b416d5eed1c256d183b318 783 SUPERFAMILY SSF48452 134 319 1.55E-26 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_15725 03048dd444b416d5eed1c256d183b318 783 SUPERFAMILY SSF48452 20 183 1.04E-25 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_15725 03048dd444b416d5eed1c256d183b318 783 Gene3D G3DSA:3.40.50.11380 429 588 6.0E-34 T 14-10-2018 TSH58p_15725 03048dd444b416d5eed1c256d183b318 783 SUPERFAMILY SSF53756 581 717 2.35E-5 T 14-10-2018 TSH58p_15725 03048dd444b416d5eed1c256d183b318 783 Pfam PF13844 Glycosyl transferase family 41 585 753 2.2E-11 T 14-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 TSH58p_15725 03048dd444b416d5eed1c256d183b318 783 Gene3D G3DSA:1.25.40.10 132 358 1.8E-33 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_15725 03048dd444b416d5eed1c256d183b318 783 Gene3D G3DSA:3.40.50.2000 589 763 2.9E-42 T 14-10-2018 TSH58p_30645 c66bc0d07ee05fc635c43184fd7806f0 280 SUPERFAMILY SSF102215 18 275 2.35E-48 T 14-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 TSH58p_30645 c66bc0d07ee05fc635c43184fd7806f0 280 Pfam PF02633 Creatinine amidohydrolase 22 271 9.1E-48 T 14-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 TSH58p_30645 c66bc0d07ee05fc635c43184fd7806f0 280 Gene3D G3DSA:3.40.50.10310 13 278 5.3E-50 T 14-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 TSH58p_26280 deb0f12e247227037a26ffd4c25a0bdc 133 SUPERFAMILY SSF53062 1 130 9.81E-38 T 14-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 TSH58p_26280 deb0f12e247227037a26ffd4c25a0bdc 133 Pfam PF03610 PTS system fructose IIA component 3 112 7.4E-31 T 14-10-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 TSH58p_26280 deb0f12e247227037a26ffd4c25a0bdc 133 Gene3D G3DSA:3.40.50.510 1 132 1.2E-40 T 14-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 TSH58p_12920 2aec08e304ae1206f4b33dd9b4ef686b 299 TIGRFAM TIGR00761 argB: acetylglutamate kinase 30 273 3.2E-80 T 14-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TSH58p_12920 2aec08e304ae1206f4b33dd9b4ef686b 299 SUPERFAMILY SSF53633 7 297 6.55E-97 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSH58p_12920 2aec08e304ae1206f4b33dd9b4ef686b 299 PIRSF PIRSF000728 14 298 4.7E-113 T 14-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TSH58p_12920 2aec08e304ae1206f4b33dd9b4ef686b 299 PRINTS PR00474 Glutamate 5-kinase family signature 198 225 2.1E-8 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TSH58p_12920 2aec08e304ae1206f4b33dd9b4ef686b 299 PRINTS PR00474 Glutamate 5-kinase family signature 60 74 2.1E-8 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TSH58p_12920 2aec08e304ae1206f4b33dd9b4ef686b 299 PRINTS PR00474 Glutamate 5-kinase family signature 248 268 2.1E-8 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TSH58p_12920 2aec08e304ae1206f4b33dd9b4ef686b 299 Hamap MF_00082 Acetylglutamate kinase [argB]. 28 291 50.56 T 14-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TSH58p_12920 2aec08e304ae1206f4b33dd9b4ef686b 299 Gene3D G3DSA:3.40.1160.10 4 298 5.7E-102 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSH58p_12920 2aec08e304ae1206f4b33dd9b4ef686b 299 Pfam PF00696 Amino acid kinase family 30 273 2.2E-52 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TSH58p_27480 c8ec26a9ccaa567da4d097af743b1957 807 Pfam PF01804 Penicillin amidase 55 779 2.8E-220 T 14-10-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 TSH58p_27480 c8ec26a9ccaa567da4d097af743b1957 807 Gene3D G3DSA:1.10.1400.10 550 683 9.4E-174 T 14-10-2018 TSH58p_27480 c8ec26a9ccaa567da4d097af743b1957 807 Gene3D G3DSA:2.30.120.10 328 401 9.4E-174 T 14-10-2018 TSH58p_27480 c8ec26a9ccaa567da4d097af743b1957 807 PIRSF PIRSF001227 13 800 1.4E-189 T 14-10-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 TSH58p_27480 c8ec26a9ccaa567da4d097af743b1957 807 Gene3D G3DSA:3.60.20.10 256 776 9.4E-174 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_27480 c8ec26a9ccaa567da4d097af743b1957 807 SUPERFAMILY SSF56235 51 800 7.2E-222 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_27480 c8ec26a9ccaa567da4d097af743b1957 807 Gene3D G3DSA:1.10.439.10 30 193 1.0E-61 T 14-10-2018 IPR023343 Penicillin amidase type, domain 1 GO:0016811 TSH58p_06560 5745d70d346d6a90671a863cd98345d0 396 Pfam PF12221 Bacterial membrane protein N terminal 1 67 1.5E-4 T 14-10-2018 IPR020980 Menbrane protein HflK, N-terminal TSH58p_06560 5745d70d346d6a90671a863cd98345d0 396 SMART SM00244 88 266 1.2E-22 T 14-10-2018 IPR001107 Band 7 domain TSH58p_06560 5745d70d346d6a90671a863cd98345d0 396 TIGRFAM TIGR01933 hflK: HflK protein 90 361 1.1E-85 T 14-10-2018 IPR010201 HflK GO:0016021 TSH58p_06560 5745d70d346d6a90671a863cd98345d0 396 SUPERFAMILY SSF117892 153 273 3.01E-20 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily TSH58p_06560 5745d70d346d6a90671a863cd98345d0 396 Pfam PF01145 SPFH domain / Band 7 family 92 281 1.2E-24 T 14-10-2018 IPR001107 Band 7 domain TSH58p_06560 5745d70d346d6a90671a863cd98345d0 396 Gene3D G3DSA:3.30.479.30 146 256 3.0E-21 T 14-10-2018 TSH58p_11410 7d451ac54cf52c4b30a0aa3a627c2733 312 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 181 239 3.8E-13 T 14-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 TSH58p_11410 7d451ac54cf52c4b30a0aa3a627c2733 312 Gene3D G3DSA:3.30.2350.10 1 242 5.2E-84 T 14-10-2018 TSH58p_11410 7d451ac54cf52c4b30a0aa3a627c2733 312 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 32 180 1.5E-50 T 14-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 TSH58p_11410 7d451ac54cf52c4b30a0aa3a627c2733 312 SUPERFAMILY SSF55120 10 237 1.47E-76 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSH58p_11410 7d451ac54cf52c4b30a0aa3a627c2733 312 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 10 310 18.566 T 14-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSH58p_11410 7d451ac54cf52c4b30a0aa3a627c2733 312 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 11 219 3.1E-69 T 14-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSH58p_13845 36c0170b5c3b9f94208ce1933060a567 504 Gene3D G3DSA:2.102.10.10 419 504 5.9E-23 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TSH58p_13845 36c0170b5c3b9f94208ce1933060a567 504 Gene3D G3DSA:3.50.50.60 23 372 8.1E-50 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_13845 36c0170b5c3b9f94208ce1933060a567 504 Pfam PF00355 Rieske [2Fe-2S] domain 422 496 2.4E-11 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TSH58p_13845 36c0170b5c3b9f94208ce1933060a567 504 Pfam PF01266 FAD dependent oxidoreductase 23 371 2.3E-44 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TSH58p_13845 36c0170b5c3b9f94208ce1933060a567 504 PRINTS PR00162 Rieske 2Fe-2S subunit signature 470 482 6.4E-6 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 TSH58p_13845 36c0170b5c3b9f94208ce1933060a567 504 PRINTS PR00162 Rieske 2Fe-2S subunit signature 482 494 6.4E-6 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 TSH58p_13845 36c0170b5c3b9f94208ce1933060a567 504 PRINTS PR00162 Rieske 2Fe-2S subunit signature 449 460 6.4E-6 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 TSH58p_13845 36c0170b5c3b9f94208ce1933060a567 504 Gene3D G3DSA:3.30.9.10 116 330 8.1E-50 T 14-10-2018 TSH58p_13845 36c0170b5c3b9f94208ce1933060a567 504 SUPERFAMILY SSF50022 419 496 8.64E-22 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TSH58p_13845 36c0170b5c3b9f94208ce1933060a567 504 SUPERFAMILY SSF51905 22 380 1.09E-33 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_12785 f521f16e1944417326b093e1eada90ce 214 SUPERFAMILY SSF51366 4 211 2.2E-56 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TSH58p_12785 f521f16e1944417326b093e1eada90ce 214 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 3 214 38.547 T 14-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 TSH58p_12785 f521f16e1944417326b093e1eada90ce 214 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 5 209 2.3E-43 T 14-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 TSH58p_12785 f521f16e1944417326b093e1eada90ce 214 Gene3D G3DSA:3.20.20.70 2 214 2.1E-62 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_12780 e4d3c848d6ad1233fc8cdbf8c6cbad6a 237 SMART SM00934 11 233 9.6E-80 T 14-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSH58p_12780 e4d3c848d6ad1233fc8cdbf8c6cbad6a 237 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 14 233 1.3E-47 T 14-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSH58p_12780 e4d3c848d6ad1233fc8cdbf8c6cbad6a 237 Gene3D G3DSA:3.20.20.70 8 237 3.2E-81 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_12780 e4d3c848d6ad1233fc8cdbf8c6cbad6a 237 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 11 233 1.0E-37 T 14-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSH58p_12780 e4d3c848d6ad1233fc8cdbf8c6cbad6a 237 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 64 77 - T 14-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSH58p_12780 e4d3c848d6ad1233fc8cdbf8c6cbad6a 237 SUPERFAMILY SSF51366 10 236 2.54E-68 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TSH58p_12780 e4d3c848d6ad1233fc8cdbf8c6cbad6a 237 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 9 237 32.342 T 14-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSH58p_23960 5d6d320c07037de58b8646a8b631bdd1 926 Pfam PF07584 Aerotolerance regulator N-terminal 8 81 6.3E-17 T 14-10-2018 IPR024163 Aerotolerance regulator, N-terminal TSH58p_23960 5d6d320c07037de58b8646a8b631bdd1 926 TIGRFAM TIGR02226 two_anch: N-terminal double-transmembrane domain 8 86 3.0E-18 T 14-10-2018 IPR011933 Double transmembrane domain TSH58p_23960 5d6d320c07037de58b8646a8b631bdd1 926 Gene3D G3DSA:3.40.50.880 306 518 8.9E-8 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_23960 5d6d320c07037de58b8646a8b631bdd1 926 Pfam PF13709 Domain of unknown function (DUF4159) 705 906 5.9E-56 T 14-10-2018 IPR025297 Domain of unknown function DUF4159 TSH58p_23960 5d6d320c07037de58b8646a8b631bdd1 926 Gene3D G3DSA:3.40.50.12140 699 908 1.3E-77 T 14-10-2018 TSH58p_23960 5d6d320c07037de58b8646a8b631bdd1 926 SUPERFAMILY SSF52317 354 516 7.32E-9 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_23305 693ddc594506ca011c844f8739a7cde5 447 Pfam PF05936 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE 23 388 1.3E-45 T 14-10-2018 IPR010263 Type VI secretion protein, VC_A0114 TSH58p_28250 50111339880d58579b7beab2da6a2e5a 415 SMART SM00388 175 244 7.2E-18 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_28250 50111339880d58579b7beab2da6a2e5a 415 SUPERFAMILY SSF52172 17 173 1.57E-35 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_28250 50111339880d58579b7beab2da6a2e5a 415 Gene3D G3DSA:1.10.287.130 143 241 6.4E-25 T 14-10-2018 TSH58p_28250 50111339880d58579b7beab2da6a2e5a 415 SUPERFAMILY SSF55874 233 399 9.17E-43 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_28250 50111339880d58579b7beab2da6a2e5a 415 Pfam PF00512 His Kinase A (phospho-acceptor) domain 176 243 7.4E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_28250 50111339880d58579b7beab2da6a2e5a 415 Gene3D G3DSA:3.30.565.10 248 402 1.0E-40 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_28250 50111339880d58579b7beab2da6a2e5a 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 384 397 1.5E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_28250 50111339880d58579b7beab2da6a2e5a 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 378 1.5E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_28250 50111339880d58579b7beab2da6a2e5a 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 343 353 1.5E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_28250 50111339880d58579b7beab2da6a2e5a 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 325 339 1.5E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_28250 50111339880d58579b7beab2da6a2e5a 415 SMART SM00387 288 400 5.8E-34 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_28250 50111339880d58579b7beab2da6a2e5a 415 SMART SM00448 17 131 4.6E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_28250 50111339880d58579b7beab2da6a2e5a 415 SUPERFAMILY SSF47384 161 241 1.18E-17 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_28250 50111339880d58579b7beab2da6a2e5a 415 Pfam PF00072 Response regulator receiver domain 19 131 1.8E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_28250 50111339880d58579b7beab2da6a2e5a 415 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 289 398 1.0E-26 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_28250 50111339880d58579b7beab2da6a2e5a 415 Gene3D G3DSA:3.40.50.2300 10 142 4.5E-31 T 14-10-2018 TSH58p_21810 cd67f4bfed6c204493336c47e38ae1f8 535 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 2 525 51.33 T 14-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 TSH58p_21810 cd67f4bfed6c204493336c47e38ae1f8 535 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 146 5.0E-21 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSH58p_21810 cd67f4bfed6c204493336c47e38ae1f8 535 PRINTS PR00315 GTP-binding elongation factor signature 135 144 2.4E-12 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_21810 cd67f4bfed6c204493336c47e38ae1f8 535 PRINTS PR00315 GTP-binding elongation factor signature 83 93 2.4E-12 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_21810 cd67f4bfed6c204493336c47e38ae1f8 535 PRINTS PR00315 GTP-binding elongation factor signature 99 110 2.4E-12 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_21810 cd67f4bfed6c204493336c47e38ae1f8 535 PRINTS PR00315 GTP-binding elongation factor signature 13 26 2.4E-12 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_21810 cd67f4bfed6c204493336c47e38ae1f8 535 PRINTS PR00315 GTP-binding elongation factor signature 63 71 2.4E-12 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_21810 cd67f4bfed6c204493336c47e38ae1f8 535 SUPERFAMILY SSF54980 391 462 5.04E-13 T 14-10-2018 IPR035647 EF-G domain III/V-like TSH58p_21810 cd67f4bfed6c204493336c47e38ae1f8 535 Pfam PF00009 Elongation factor Tu GTP binding domain 11 275 3.4E-49 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_21810 cd67f4bfed6c204493336c47e38ae1f8 535 Pfam PF16658 Class II release factor RF3, C-terminal domain 385 512 1.1E-42 T 14-10-2018 IPR032090 Peptide chain release factor 3, C-terminal TSH58p_21810 cd67f4bfed6c204493336c47e38ae1f8 535 SUPERFAMILY SSF50447 259 391 3.53E-28 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSH58p_21810 cd67f4bfed6c204493336c47e38ae1f8 535 Gene3D G3DSA:3.40.50.300 108 273 3.1E-106 T 14-10-2018 TSH58p_21810 cd67f4bfed6c204493336c47e38ae1f8 535 SUPERFAMILY SSF52540 9 275 2.26E-83 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_21810 cd67f4bfed6c204493336c47e38ae1f8 535 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 1 526 9.0E-214 T 14-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 TSH58p_21810 cd67f4bfed6c204493336c47e38ae1f8 535 Gene3D G3DSA:3.40.50.300 71 377 3.1E-106 T 14-10-2018 TSH58p_21810 cd67f4bfed6c204493336c47e38ae1f8 535 Gene3D G3DSA:3.30.70.3280 388 528 5.9E-45 T 14-10-2018 IPR038467 Peptide chain release factor 3, C-terminal domain superfamily TSH58p_21810 cd67f4bfed6c204493336c47e38ae1f8 535 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 56 71 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site TSH58p_30810 8404f1781d5970895b59265c657967aa 314 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 9 136 7.5E-5 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 TSH58p_30810 8404f1781d5970895b59265c657967aa 314 SUPERFAMILY SSF48179 171 276 1.02E-20 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_30810 8404f1781d5970895b59265c657967aa 314 SUPERFAMILY SSF51735 9 169 5.79E-25 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_30810 8404f1781d5970895b59265c657967aa 314 Gene3D G3DSA:1.10.1040.10 179 292 1.4E-26 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSH58p_30810 8404f1781d5970895b59265c657967aa 314 Gene3D G3DSA:3.40.50.720 9 177 2.6E-30 T 14-10-2018 TSH58p_30810 8404f1781d5970895b59265c657967aa 314 Pfam PF09130 Domain of unknown function (DUF1932) 198 268 4.4E-12 T 14-10-2018 IPR015814 Phosphogluconate dehydrogenase, NAD-binding, putative, C-terminal TSH58p_13865 8821855c43be194dfa55ed3e622a1dc5 322 Pfam PF10282 Lactonase, 7-bladed beta-propeller 24 81 4.9E-5 T 14-10-2018 IPR019405 Lactonase, 7-bladed beta propeller TSH58p_13865 8821855c43be194dfa55ed3e622a1dc5 322 Pfam PF10282 Lactonase, 7-bladed beta-propeller 181 302 4.1E-5 T 14-10-2018 IPR019405 Lactonase, 7-bladed beta propeller TSH58p_13865 8821855c43be194dfa55ed3e622a1dc5 322 TIGRFAM TIGR03866 PQQ_ABC_repeats: PQQ-dependent catabolism-associated beta-propeller protein 16 321 1.1E-160 T 14-10-2018 IPR022456 PQQ-dependent catabolism-associated beta-propeller protein TSH58p_13865 8821855c43be194dfa55ed3e622a1dc5 322 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 24 61 8.3E-13 T 14-10-2018 IPR011964 YVTN beta-propeller repeat TSH58p_13865 8821855c43be194dfa55ed3e622a1dc5 322 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 280 320 3.2E-15 T 14-10-2018 IPR011964 YVTN beta-propeller repeat TSH58p_13865 8821855c43be194dfa55ed3e622a1dc5 322 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 104 145 6.9E-11 T 14-10-2018 IPR011964 YVTN beta-propeller repeat TSH58p_13865 8821855c43be194dfa55ed3e622a1dc5 322 SUPERFAMILY SSF50974 5 320 4.97E-83 T 14-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 TSH58p_13865 8821855c43be194dfa55ed3e622a1dc5 322 Gene3D G3DSA:2.130.10.10 22 224 1.4E-56 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TSH58p_13865 8821855c43be194dfa55ed3e622a1dc5 322 Gene3D G3DSA:2.130.10.10 225 321 1.3E-24 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TSH58p_00480 d88ac7ff2852306182eab925db018907 299 SUPERFAMILY SSF51569 1 291 3.66E-75 T 14-10-2018 TSH58p_00480 d88ac7ff2852306182eab925db018907 299 ProSitePatterns PS01062 Hydroxymethylglutaryl-coenzyme A lyase active site. 233 242 - T 14-10-2018 IPR000138 Hydroxymethylglutaryl-CoA lyase, active site GO:0004419 KEGG: 00072+4.1.3.4|KEGG: 00280+4.1.3.4|KEGG: 00281+4.1.3.4|KEGG: 00650+4.1.3.4|MetaCyc: PWY-5074|Reactome: R-HSA-77111|Reactome: R-HSA-9033241 TSH58p_00480 d88ac7ff2852306182eab925db018907 299 Gene3D G3DSA:3.20.20.70 1 298 2.9E-138 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_00480 d88ac7ff2852306182eab925db018907 299 Pfam PF00682 HMGL-like 7 280 8.2E-54 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 TSH58p_21055 80c01e28b771d49df8807f653dd93d6d 516 Pfam PF14559 Tetratricopeptide repeat 116 174 7.1E-6 T 14-10-2018 TSH58p_21055 80c01e28b771d49df8807f653dd93d6d 516 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 385 446 4.5E-8 T 14-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 TSH58p_21055 80c01e28b771d49df8807f653dd93d6d 516 Pfam PF07719 Tetratricopeptide repeat 75 104 4.2E-6 T 14-10-2018 IPR013105 Tetratricopeptide repeat 2 TSH58p_21055 80c01e28b771d49df8807f653dd93d6d 516 SUPERFAMILY SSF53756 224 493 9.42E-26 T 14-10-2018 TSH58p_21055 80c01e28b771d49df8807f653dd93d6d 516 Gene3D G3DSA:1.25.40.10 5 108 2.4E-18 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_21055 80c01e28b771d49df8807f653dd93d6d 516 Gene3D G3DSA:1.25.40.10 110 210 3.5E-17 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_21055 80c01e28b771d49df8807f653dd93d6d 516 SUPERFAMILY SSF48452 8 200 4.46E-32 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_21055 80c01e28b771d49df8807f653dd93d6d 516 Pfam PF13432 Tetratricopeptide repeat 8 67 2.8E-5 T 14-10-2018 TSH58p_21055 80c01e28b771d49df8807f653dd93d6d 516 Pfam PF07721 Tetratricopeptide repeat 179 199 0.98 T 14-10-2018 IPR011717 Tetratricopeptide TPR-4 GO:0042802 TSH58p_21055 80c01e28b771d49df8807f653dd93d6d 516 SMART SM00028 4 37 18.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_21055 80c01e28b771d49df8807f653dd93d6d 516 SMART SM00028 72 105 7.8E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_21055 80c01e28b771d49df8807f653dd93d6d 516 SMART SM00028 38 71 120.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_21055 80c01e28b771d49df8807f653dd93d6d 516 SMART SM00028 140 173 0.007 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_21055 80c01e28b771d49df8807f653dd93d6d 516 Gene3D G3DSA:3.40.50.2000 371 465 1.3E-10 T 14-10-2018 TSH58p_17530 99cf85d27324a13053464dd482f2badc 402 Gene3D G3DSA:3.40.50.620 14 275 1.5E-25 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_17530 99cf85d27324a13053464dd482f2badc 402 SUPERFAMILY SSF52402 22 222 8.87E-18 T 14-10-2018 TSH58p_17530 99cf85d27324a13053464dd482f2badc 402 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 39 222 1.4E-8 T 14-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 TSH58p_27995 63359ffdcbe0770e7a58735ab1c8e2d0 189 SMART SM00357 21 85 2.0E-10 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 TSH58p_27995 63359ffdcbe0770e7a58735ab1c8e2d0 189 SMART SM00357 125 189 2.5E-19 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 TSH58p_27995 63359ffdcbe0770e7a58735ab1c8e2d0 189 SUPERFAMILY SSF50249 20 83 4.0E-16 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_27995 63359ffdcbe0770e7a58735ab1c8e2d0 189 Gene3D G3DSA:2.40.50.140 121 189 1.4E-22 T 14-10-2018 TSH58p_27995 63359ffdcbe0770e7a58735ab1c8e2d0 189 SUPERFAMILY SSF50249 123 188 3.43E-19 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_27995 63359ffdcbe0770e7a58735ab1c8e2d0 189 PRINTS PR00050 Cold shock protein signature 147 156 9.7E-12 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_27995 63359ffdcbe0770e7a58735ab1c8e2d0 189 PRINTS PR00050 Cold shock protein signature 126 141 9.7E-12 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_27995 63359ffdcbe0770e7a58735ab1c8e2d0 189 PRINTS PR00050 Cold shock protein signature 162 180 9.7E-12 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_27995 63359ffdcbe0770e7a58735ab1c8e2d0 189 ProSitePatterns PS00352 'Cold-shock' domain signature. 137 156 - T 14-10-2018 IPR019844 Cold-shock conserved site TSH58p_27995 63359ffdcbe0770e7a58735ab1c8e2d0 189 Pfam PF00313 'Cold-shock' DNA-binding domain 21 82 1.7E-14 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_27995 63359ffdcbe0770e7a58735ab1c8e2d0 189 Pfam PF00313 'Cold-shock' DNA-binding domain 125 187 9.8E-22 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_27995 63359ffdcbe0770e7a58735ab1c8e2d0 189 Gene3D G3DSA:2.40.50.140 13 94 1.3E-17 T 14-10-2018 TSH58p_07100 d80e58bea0c9e3e5aa9803e95408a7b5 243 Pfam PF00106 short chain dehydrogenase 7 197 1.3E-53 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_07100 d80e58bea0c9e3e5aa9803e95408a7b5 243 Gene3D G3DSA:3.40.50.720 4 241 2.5E-70 T 14-10-2018 TSH58p_07100 d80e58bea0c9e3e5aa9803e95408a7b5 243 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 197 1.1E-4 T 14-10-2018 TSH58p_07100 d80e58bea0c9e3e5aa9803e95408a7b5 243 SUPERFAMILY SSF51735 3 228 3.96E-66 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_07100 d80e58bea0c9e3e5aa9803e95408a7b5 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.1E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_07100 d80e58bea0c9e3e5aa9803e95408a7b5 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.1E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_07100 d80e58bea0c9e3e5aa9803e95408a7b5 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.1E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_07100 d80e58bea0c9e3e5aa9803e95408a7b5 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.2E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_07100 d80e58bea0c9e3e5aa9803e95408a7b5 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.2E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_07100 d80e58bea0c9e3e5aa9803e95408a7b5 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.2E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_07100 d80e58bea0c9e3e5aa9803e95408a7b5 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.2E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_07100 d80e58bea0c9e3e5aa9803e95408a7b5 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.2E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_07100 d80e58bea0c9e3e5aa9803e95408a7b5 243 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_11435 360543f979ab438a489e99965531ead6 297 Pfam PF04228 Putative neutral zinc metallopeptidase 1 292 9.8E-121 T 14-10-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative TSH58p_11435 360543f979ab438a489e99965531ead6 297 SUPERFAMILY SSF55486 95 228 1.1E-5 T 14-10-2018 TSH58p_18620 917ec698c3500820ebcfda0467deab0e 223 Pfam PF03741 Integral membrane protein TerC family 15 210 4.0E-42 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 TSH58p_18620 917ec698c3500820ebcfda0467deab0e 223 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 13 210 7.5E-63 T 14-10-2018 IPR022301 Integral membrane protein YjbE TSH58p_02795 d411b0086bb34dd6675a483f051ffb26 549 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 126 483 9.4E-95 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase TSH58p_02795 d411b0086bb34dd6675a483f051ffb26 549 SUPERFAMILY SSF53383 115 474 1.22E-97 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_02795 d411b0086bb34dd6675a483f051ffb26 549 TIGRFAM TIGR02379 ECA_wecE: TDP-4-keto-6-deoxy-D-glucose transaminase 116 487 1.9E-177 T 14-10-2018 IPR012749 dTDP-4-amino-4,6-dideoxygalactose transaminase WecE-like MetaCyc: PWY-7315 TSH58p_02795 d411b0086bb34dd6675a483f051ffb26 549 Gene3D G3DSA:3.90.1150.10 363 488 2.6E-26 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_02795 d411b0086bb34dd6675a483f051ffb26 549 Gene3D G3DSA:3.40.640.10 104 361 7.3E-83 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_02795 d411b0086bb34dd6675a483f051ffb26 549 Pfam PF08889 WbqC-like protein family 9 83 3.4E-7 T 14-10-2018 IPR014985 WbqC-like protein family TSH58p_26005 ec31ab2f91ef469d9de52a2a5c071a19 334 Gene3D G3DSA:3.40.50.300 56 263 3.4E-82 T 14-10-2018 TSH58p_26005 ec31ab2f91ef469d9de52a2a5c071a19 334 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 22 326 7.2E-103 T 14-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TSH58p_26005 ec31ab2f91ef469d9de52a2a5c071a19 334 SUPERFAMILY SSF52540 13 328 5.3E-90 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_26005 ec31ab2f91ef469d9de52a2a5c071a19 334 Gene3D G3DSA:1.20.5.170 11 55 6.4E-20 T 14-10-2018 TSH58p_26005 ec31ab2f91ef469d9de52a2a5c071a19 334 Gene3D G3DSA:1.10.287.130 266 329 6.7E-19 T 14-10-2018 TSH58p_26005 ec31ab2f91ef469d9de52a2a5c071a19 334 Pfam PF03308 ArgK protein 27 296 1.1E-103 T 14-10-2018 TSH58p_27400 ea4a3f15f182e314c48195f0d404e110 368 SUPERFAMILY SSF111369 189 283 2.22E-11 T 14-10-2018 TSH58p_27400 ea4a3f15f182e314c48195f0d404e110 368 Gene3D G3DSA:2.40.30.170 228 351 7.6E-37 T 14-10-2018 TSH58p_27400 ea4a3f15f182e314c48195f0d404e110 368 Pfam PF00529 HlyD membrane-fusion protein of T1SS 290 341 2.4E-10 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 TSH58p_27400 ea4a3f15f182e314c48195f0d404e110 368 Gene3D G3DSA:1.10.287.470 81 111 3.0E-10 T 14-10-2018 TSH58p_27400 ea4a3f15f182e314c48195f0d404e110 368 Gene3D G3DSA:2.40.50.100 49 80 3.0E-10 T 14-10-2018 TSH58p_27400 ea4a3f15f182e314c48195f0d404e110 368 Gene3D G3DSA:1.10.287.470 113 181 8.8E-8 T 14-10-2018 TSH58p_27400 ea4a3f15f182e314c48195f0d404e110 368 SUPERFAMILY SSF111369 48 142 8.5E-9 T 14-10-2018 TSH58p_27400 ea4a3f15f182e314c48195f0d404e110 368 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 45 289 3.0E-18 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain TSH58p_29000 dab33f18d9c484f87af032cfdddcc51c 413 Gene3D G3DSA:3.40.50.1100 120 216 5.3E-112 T 14-10-2018 TSH58p_29000 dab33f18d9c484f87af032cfdddcc51c 413 TIGRFAM TIGR00260 thrC: threonine synthase 68 384 4.0E-51 T 14-10-2018 IPR004450 Threonine synthase-like TSH58p_29000 dab33f18d9c484f87af032cfdddcc51c 413 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 84 387 6.4E-70 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TSH58p_29000 dab33f18d9c484f87af032cfdddcc51c 413 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 111 125 - T 14-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 TSH58p_29000 dab33f18d9c484f87af032cfdddcc51c 413 SUPERFAMILY SSF53686 6 394 4.06E-89 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TSH58p_29000 dab33f18d9c484f87af032cfdddcc51c 413 Gene3D G3DSA:3.40.50.1100 69 394 5.3E-112 T 14-10-2018 TSH58p_24680 998689186bd03793271c3d0f581ad3d5 371 Gene3D G3DSA:3.40.630.10 2 284 1.5E-83 T 14-10-2018 TSH58p_24680 998689186bd03793271c3d0f581ad3d5 371 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 32 358 3.7E-31 T 14-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 TSH58p_24680 998689186bd03793271c3d0f581ad3d5 371 SUPERFAMILY SSF53187 19 361 3.24E-39 T 14-10-2018 TSH58p_28515 89e42dcae7d93d692b2004f8a13b5dd2 266 SUPERFAMILY SSF55729 27 172 9.35E-14 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_28515 89e42dcae7d93d692b2004f8a13b5dd2 266 Gene3D G3DSA:3.40.630.30 2 183 1.7E-11 T 14-10-2018 TSH58p_29085 8ed580df7f2729fc51fd88c3f0cbeb8a 266 Pfam PF02661 Fic/DOC family 96 186 1.2E-11 T 14-10-2018 IPR003812 Fido domain TSH58p_29085 8ed580df7f2729fc51fd88c3f0cbeb8a 266 Gene3D G3DSA:1.10.3290.10 6 246 2.2E-35 T 14-10-2018 IPR036597 Fido-like domain superfamily TSH58p_29085 8ed580df7f2729fc51fd88c3f0cbeb8a 266 SUPERFAMILY SSF140931 74 240 4.58E-26 T 14-10-2018 IPR036597 Fido-like domain superfamily TSH58p_10305 14e9cf535c176cac9cecf14d76f6cba6 563 SUPERFAMILY SSF56634 2 494 3.01E-184 T 14-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TSH58p_10305 14e9cf535c176cac9cecf14d76f6cba6 563 Pfam PF06628 Catalase-related immune-responsive 426 486 1.0E-14 T 14-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TSH58p_10305 14e9cf535c176cac9cecf14d76f6cba6 563 SMART SM01060 9 403 2.6E-236 T 14-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TSH58p_10305 14e9cf535c176cac9cecf14d76f6cba6 563 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 340 348 - T 14-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TSH58p_10305 14e9cf535c176cac9cecf14d76f6cba6 563 Gene3D G3DSA:2.40.180.10 5 504 1.3E-201 T 14-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 TSH58p_10305 14e9cf535c176cac9cecf14d76f6cba6 563 PIRSF PIRSF038928 1 493 1.2E-168 T 14-10-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TSH58p_10305 14e9cf535c176cac9cecf14d76f6cba6 563 Pfam PF00199 Catalase 9 397 1.0E-164 T 14-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TSH58p_10305 14e9cf535c176cac9cecf14d76f6cba6 563 PRINTS PR00067 Catalase signature 111 128 1.0E-64 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TSH58p_10305 14e9cf535c176cac9cecf14d76f6cba6 563 PRINTS PR00067 Catalase signature 90 108 1.0E-64 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TSH58p_10305 14e9cf535c176cac9cecf14d76f6cba6 563 PRINTS PR00067 Catalase signature 130 148 1.0E-64 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TSH58p_10305 14e9cf535c176cac9cecf14d76f6cba6 563 PRINTS PR00067 Catalase signature 295 322 1.0E-64 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TSH58p_10305 14e9cf535c176cac9cecf14d76f6cba6 563 PRINTS PR00067 Catalase signature 327 353 1.0E-64 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TSH58p_10305 14e9cf535c176cac9cecf14d76f6cba6 563 PRINTS PR00067 Catalase signature 22 45 1.0E-64 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TSH58p_11595 b01b0e126f066287bcde69ed7877a5de 138 Gene3D G3DSA:3.10.129.10 2 137 6.1E-33 T 14-10-2018 TSH58p_11595 b01b0e126f066287bcde69ed7877a5de 138 Pfam PF13279 Thioesterase-like superfamily 18 133 1.7E-11 T 14-10-2018 TSH58p_11595 b01b0e126f066287bcde69ed7877a5de 138 SUPERFAMILY SSF54637 10 137 2.01E-30 T 14-10-2018 IPR029069 HotDog domain superfamily TSH58p_14515 66a314e479cbcfbe20ecc033cd107566 144 Pfam PF12616 Protein of unknown function (DUF3775) 67 136 1.0E-19 T 14-10-2018 IPR022254 Protein of unknown function DUF3775 TSH58p_21730 111f1c4f63b6cdd3de0de33f766b2866 1048 Pfam PF00873 AcrB/AcrD/AcrF family 4 1014 6.7E-281 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_21730 111f1c4f63b6cdd3de0de33f766b2866 1048 Gene3D G3DSA:3.30.70.1440 658 857 0.0 T 14-10-2018 TSH58p_21730 111f1c4f63b6cdd3de0de33f766b2866 1048 SUPERFAMILY SSF82693 134 325 9.24E-18 T 14-10-2018 TSH58p_21730 111f1c4f63b6cdd3de0de33f766b2866 1048 SUPERFAMILY SSF82714 707 799 2.62E-11 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_21730 111f1c4f63b6cdd3de0de33f766b2866 1048 PRINTS PR00702 Acriflavin resistance protein family signature 439 462 1.2E-69 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_21730 111f1c4f63b6cdd3de0de33f766b2866 1048 PRINTS PR00702 Acriflavin resistance protein family signature 358 379 1.2E-69 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_21730 111f1c4f63b6cdd3de0de33f766b2866 1048 PRINTS PR00702 Acriflavin resistance protein family signature 549 566 1.2E-69 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_21730 111f1c4f63b6cdd3de0de33f766b2866 1048 PRINTS PR00702 Acriflavin resistance protein family signature 331 354 1.2E-69 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_21730 111f1c4f63b6cdd3de0de33f766b2866 1048 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.2E-69 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_21730 111f1c4f63b6cdd3de0de33f766b2866 1048 PRINTS PR00702 Acriflavin resistance protein family signature 464 487 1.2E-69 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_21730 111f1c4f63b6cdd3de0de33f766b2866 1048 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.2E-69 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_21730 111f1c4f63b6cdd3de0de33f766b2866 1048 PRINTS PR00702 Acriflavin resistance protein family signature 386 410 1.2E-69 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_21730 111f1c4f63b6cdd3de0de33f766b2866 1048 PRINTS PR00702 Acriflavin resistance protein family signature 615 629 1.2E-69 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_21730 111f1c4f63b6cdd3de0de33f766b2866 1048 Gene3D G3DSA:3.30.2090.10 706 800 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_21730 111f1c4f63b6cdd3de0de33f766b2866 1048 Gene3D G3DSA:3.30.2090.10 178 268 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_21730 111f1c4f63b6cdd3de0de33f766b2866 1048 SUPERFAMILY SSF82866 797 1018 9.16E-52 T 14-10-2018 TSH58p_21730 111f1c4f63b6cdd3de0de33f766b2866 1048 Gene3D G3DSA:1.20.1640.10 510 1013 0.0 T 14-10-2018 TSH58p_21730 111f1c4f63b6cdd3de0de33f766b2866 1048 SUPERFAMILY SSF82714 182 265 8.63E-16 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_21730 111f1c4f63b6cdd3de0de33f766b2866 1048 SUPERFAMILY SSF82866 289 491 1.96E-48 T 14-10-2018 TSH58p_21730 111f1c4f63b6cdd3de0de33f766b2866 1048 Gene3D G3DSA:3.30.70.1430 564 657 0.0 T 14-10-2018 TSH58p_21730 111f1c4f63b6cdd3de0de33f766b2866 1048 Gene3D G3DSA:3.30.70.1430 40 808 0.0 T 14-10-2018 TSH58p_21730 111f1c4f63b6cdd3de0de33f766b2866 1048 SUPERFAMILY SSF82693 40 135 4.45E-24 T 14-10-2018 TSH58p_21730 111f1c4f63b6cdd3de0de33f766b2866 1048 SUPERFAMILY SSF82693 563 654 3.14E-15 T 14-10-2018 TSH58p_21730 111f1c4f63b6cdd3de0de33f766b2866 1048 Gene3D G3DSA:3.30.70.1320 134 327 0.0 T 14-10-2018 TSH58p_21730 111f1c4f63b6cdd3de0de33f766b2866 1048 Gene3D G3DSA:1.20.1640.10 10 509 0.0 T 14-10-2018 TSH58p_31685 7b5c8fb770a3e3cd6669f6600a829dd4 204 Gene3D G3DSA:3.40.30.10 1 76 1.1E-27 T 14-10-2018 TSH58p_31685 7b5c8fb770a3e3cd6669f6600a829dd4 204 Pfam PF02798 Glutathione S-transferase, N-terminal domain 1 73 1.3E-19 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 TSH58p_31685 7b5c8fb770a3e3cd6669f6600a829dd4 204 SUPERFAMILY SSF52833 1 84 1.06E-27 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_31685 7b5c8fb770a3e3cd6669f6600a829dd4 204 Pfam PF00043 Glutathione S-transferase, C-terminal domain 123 189 8.6E-9 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal TSH58p_31685 7b5c8fb770a3e3cd6669f6600a829dd4 204 Gene3D G3DSA:1.20.1050.10 83 192 4.5E-26 T 14-10-2018 TSH58p_31685 7b5c8fb770a3e3cd6669f6600a829dd4 204 SUPERFAMILY SSF47616 71 194 1.1E-25 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily TSH58p_05030 688effd68b9ba63bfab0949e036aa257 233 SUPERFAMILY SSF46894 160 229 5.1E-22 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_05030 688effd68b9ba63bfab0949e036aa257 233 SMART SM00448 19 133 6.8E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_05030 688effd68b9ba63bfab0949e036aa257 233 Pfam PF00196 Bacterial regulatory proteins, luxR family 168 223 2.0E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_05030 688effd68b9ba63bfab0949e036aa257 233 Pfam PF00072 Response regulator receiver domain 22 133 2.6E-12 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_05030 688effd68b9ba63bfab0949e036aa257 233 ProSitePatterns PS00622 LuxR-type HTH domain signature. 183 210 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_05030 688effd68b9ba63bfab0949e036aa257 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 183 8.1E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_05030 688effd68b9ba63bfab0949e036aa257 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 199 8.1E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_05030 688effd68b9ba63bfab0949e036aa257 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 199 211 8.1E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_05030 688effd68b9ba63bfab0949e036aa257 233 Gene3D G3DSA:3.40.50.12740 20 228 3.3E-44 T 14-10-2018 TSH58p_05030 688effd68b9ba63bfab0949e036aa257 233 SMART SM00421 166 223 2.3E-24 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_05030 688effd68b9ba63bfab0949e036aa257 233 SUPERFAMILY SSF52172 20 142 1.22E-19 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_27905 2ad6c65be5152d8dc14ee8339a5129a0 777 Gene3D G3DSA:1.10.1040.10 344 403 1.2E-5 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSH58p_27905 2ad6c65be5152d8dc14ee8339a5129a0 777 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 343 398 6.9E-5 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 TSH58p_27905 2ad6c65be5152d8dc14ee8339a5129a0 777 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 191 292 7.1E-16 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 TSH58p_27905 2ad6c65be5152d8dc14ee8339a5129a0 777 SUPERFAMILY SSF48179 190 301 8.33E-21 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_27905 2ad6c65be5152d8dc14ee8339a5129a0 777 Gene3D G3DSA:1.10.1040.10 193 315 3.7E-22 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSH58p_27905 2ad6c65be5152d8dc14ee8339a5129a0 777 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 6 189 1.3E-42 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 TSH58p_27905 2ad6c65be5152d8dc14ee8339a5129a0 777 Gene3D G3DSA:3.90.226.10 468 689 5.3E-29 T 14-10-2018 TSH58p_27905 2ad6c65be5152d8dc14ee8339a5129a0 777 SUPERFAMILY SSF48179 341 430 5.87E-14 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_27905 2ad6c65be5152d8dc14ee8339a5129a0 777 SUPERFAMILY SSF51735 1 190 1.23E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_27905 2ad6c65be5152d8dc14ee8339a5129a0 777 SUPERFAMILY SSF52096 463 774 1.07E-36 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_27905 2ad6c65be5152d8dc14ee8339a5129a0 777 Gene3D G3DSA:3.40.50.720 1 192 7.0E-57 T 14-10-2018 TSH58p_27905 2ad6c65be5152d8dc14ee8339a5129a0 777 Pfam PF00378 Enoyl-CoA hydratase/isomerase 470 613 1.9E-10 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TSH58p_08330 a8ccd04c7e7f6a61baf0fb162a8148a0 437 Gene3D G3DSA:2.40.37.20 35 436 3.5E-122 T 14-10-2018 TSH58p_08330 a8ccd04c7e7f6a61baf0fb162a8148a0 437 SUPERFAMILY SSF51419 52 265 3.6E-19 T 14-10-2018 IPR029066 PLP-binding barrel TSH58p_08330 a8ccd04c7e7f6a61baf0fb162a8148a0 437 Pfam PF14031 Putative serine dehydratase domain 322 419 5.7E-15 T 14-10-2018 IPR026956 D-serine dehydratase-like domain TSH58p_08330 a8ccd04c7e7f6a61baf0fb162a8148a0 437 SMART SM01119 322 423 3.7E-33 T 14-10-2018 IPR026956 D-serine dehydratase-like domain TSH58p_08330 a8ccd04c7e7f6a61baf0fb162a8148a0 437 Gene3D G3DSA:3.20.20.10 54 294 3.5E-122 T 14-10-2018 IPR029066 PLP-binding barrel TSH58p_08330 a8ccd04c7e7f6a61baf0fb162a8148a0 437 Pfam PF01168 Alanine racemase, N-terminal domain 52 260 2.6E-13 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_28710 dc9f976919c55f5f3b70103ce0961080 416 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 186 320 1.7E-28 T 14-10-2018 IPR001453 MoaB/Mog domain TSH58p_28710 dc9f976919c55f5f3b70103ce0961080 416 Pfam PF03454 MoeA C-terminal region (domain IV) 341 411 1.3E-18 T 14-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_28710 dc9f976919c55f5f3b70103ce0961080 416 SMART SM00852 189 326 8.3E-40 T 14-10-2018 IPR001453 MoaB/Mog domain TSH58p_28710 dc9f976919c55f5f3b70103ce0961080 416 Pfam PF03453 MoeA N-terminal region (domain I and II) 14 176 1.7E-39 T 14-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_28710 dc9f976919c55f5f3b70103ce0961080 416 Gene3D G3DSA:3.90.105.10 32 183 1.2E-128 T 14-10-2018 TSH58p_28710 dc9f976919c55f5f3b70103ce0961080 416 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 262 295 - T 14-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 TSH58p_28710 dc9f976919c55f5f3b70103ce0961080 416 Gene3D G3DSA:2.170.190.11 56 150 1.2E-128 T 14-10-2018 TSH58p_28710 dc9f976919c55f5f3b70103ce0961080 416 SUPERFAMILY SSF63882 13 184 1.06E-49 T 14-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_28710 dc9f976919c55f5f3b70103ce0961080 416 SUPERFAMILY SSF53218 186 329 1.05E-40 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSH58p_28710 dc9f976919c55f5f3b70103ce0961080 416 Gene3D G3DSA:2.40.340.10 337 406 1.2E-128 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_28710 dc9f976919c55f5f3b70103ce0961080 416 SUPERFAMILY SSF63867 336 414 1.09E-21 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_28710 dc9f976919c55f5f3b70103ce0961080 416 Pfam PF00994 Probable molybdopterin binding domain 191 323 2.5E-25 T 14-10-2018 IPR001453 MoaB/Mog domain TSH58p_28710 dc9f976919c55f5f3b70103ce0961080 416 Gene3D G3DSA:3.40.980.10 184 336 1.2E-128 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSH58p_31455 fac5701b61d4d700352d126ce18992ef 491 Gene3D G3DSA:3.30.420.40 1 244 3.2E-86 T 14-10-2018 TSH58p_31455 fac5701b61d4d700352d126ce18992ef 491 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 253 438 2.2E-31 T 14-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 TSH58p_31455 fac5701b61d4d700352d126ce18992ef 491 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 1 243 1.2E-70 T 14-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 TSH58p_31455 fac5701b61d4d700352d126ce18992ef 491 PIRSF PIRSF000538 1 488 7.9E-131 T 14-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 TSH58p_31455 fac5701b61d4d700352d126ce18992ef 491 Gene3D G3DSA:3.30.420.40 245 485 1.1E-78 T 14-10-2018 TSH58p_31455 fac5701b61d4d700352d126ce18992ef 491 TIGRFAM TIGR01312 XylB: xylulokinase 3 478 1.9E-170 T 14-10-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 TSH58p_31455 fac5701b61d4d700352d126ce18992ef 491 SUPERFAMILY SSF53067 245 482 6.04E-59 T 14-10-2018 TSH58p_31455 fac5701b61d4d700352d126ce18992ef 491 SUPERFAMILY SSF53067 2 246 1.11E-73 T 14-10-2018 TSH58p_04785 20a6bf29e23d99fd2fac5c6dc2f1c19a 214 SMART SM00448 1 114 8.2E-14 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_04785 20a6bf29e23d99fd2fac5c6dc2f1c19a 214 Pfam PF00072 Response regulator receiver domain 3 108 6.5E-19 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_04785 20a6bf29e23d99fd2fac5c6dc2f1c19a 214 Gene3D G3DSA:3.40.50.12740 1 209 4.8E-46 T 14-10-2018 TSH58p_04785 20a6bf29e23d99fd2fac5c6dc2f1c19a 214 SUPERFAMILY SSF46894 140 209 2.04E-18 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_04785 20a6bf29e23d99fd2fac5c6dc2f1c19a 214 SMART SM00421 148 205 2.5E-21 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_04785 20a6bf29e23d99fd2fac5c6dc2f1c19a 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 2.1E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_04785 20a6bf29e23d99fd2fac5c6dc2f1c19a 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 2.1E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_04785 20a6bf29e23d99fd2fac5c6dc2f1c19a 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 2.1E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_04785 20a6bf29e23d99fd2fac5c6dc2f1c19a 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 204 9.4E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_04785 20a6bf29e23d99fd2fac5c6dc2f1c19a 214 SUPERFAMILY SSF52172 1 126 2.7E-23 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_10770 d9ea19e823fad8da1470aaaf48fe830b 128 SUPERFAMILY SSF46785 26 114 2.27E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_10770 d9ea19e823fad8da1470aaaf48fe830b 128 Gene3D G3DSA:1.10.10.10 3 122 1.2E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_10770 d9ea19e823fad8da1470aaaf48fe830b 128 Pfam PF13463 Winged helix DNA-binding domain 41 101 1.1E-4 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_28020 42e714d092f3e132d67e21b0de128208 755 Gene3D G3DSA:3.30.420.350 481 724 6.5E-117 T 14-10-2018 TSH58p_28020 42e714d092f3e132d67e21b0de128208 755 Pfam PF00708 Acylphosphatase 5 86 2.7E-17 T 14-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TSH58p_28020 42e714d092f3e132d67e21b0de128208 755 ProSitePatterns PS00150 Acylphosphatase signature 1. 8 18 - T 14-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TSH58p_28020 42e714d092f3e132d67e21b0de128208 755 Gene3D G3DSA:3.30.110.120 237 370 2.5E-136 T 14-10-2018 TSH58p_28020 42e714d092f3e132d67e21b0de128208 755 Pfam PF01300 Telomere recombination 194 383 1.9E-52 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 TSH58p_28020 42e714d092f3e132d67e21b0de128208 755 Gene3D G3DSA:3.30.420.360 382 736 6.5E-117 T 14-10-2018 TSH58p_28020 42e714d092f3e132d67e21b0de128208 755 SUPERFAMILY SSF55821 171 389 2.69E-49 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily TSH58p_28020 42e714d092f3e132d67e21b0de128208 755 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 6 736 5.1E-221 T 14-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 TSH58p_28020 42e714d092f3e132d67e21b0de128208 755 Pfam PF07503 HypF finger 154 185 1.1E-16 T 14-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 TSH58p_28020 42e714d092f3e132d67e21b0de128208 755 Pfam PF07503 HypF finger 104 136 1.6E-16 T 14-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 TSH58p_28020 42e714d092f3e132d67e21b0de128208 755 PIRSF PIRSF006256 1 744 5.9E-274 T 14-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 TSH58p_28020 42e714d092f3e132d67e21b0de128208 755 SUPERFAMILY SSF54975 2 87 7.85E-22 T 14-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TSH58p_28020 42e714d092f3e132d67e21b0de128208 755 Gene3D G3DSA:3.90.870.50 6 361 2.5E-136 T 14-10-2018 TSH58p_24770 34f738be82fc28a43e6485a8b8e8de27 435 PIRSF PIRSF000099 6 430 1.6E-159 T 14-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TSH58p_24770 34f738be82fc28a43e6485a8b8e8de27 435 Pfam PF00815 Histidinol dehydrogenase 23 429 3.2E-167 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TSH58p_24770 34f738be82fc28a43e6485a8b8e8de27 435 SUPERFAMILY SSF53720 28 429 4.9E-83 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSH58p_24770 34f738be82fc28a43e6485a8b8e8de27 435 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 3 429 41.211 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TSH58p_24770 34f738be82fc28a43e6485a8b8e8de27 435 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 230 262 - T 14-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 TSH58p_24770 34f738be82fc28a43e6485a8b8e8de27 435 PRINTS PR00083 Histidinol dehydrogenase signature 322 347 9.4E-84 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TSH58p_24770 34f738be82fc28a43e6485a8b8e8de27 435 PRINTS PR00083 Histidinol dehydrogenase signature 34 58 9.4E-84 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TSH58p_24770 34f738be82fc28a43e6485a8b8e8de27 435 PRINTS PR00083 Histidinol dehydrogenase signature 252 271 9.4E-84 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TSH58p_24770 34f738be82fc28a43e6485a8b8e8de27 435 PRINTS PR00083 Histidinol dehydrogenase signature 201 226 9.4E-84 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TSH58p_24770 34f738be82fc28a43e6485a8b8e8de27 435 PRINTS PR00083 Histidinol dehydrogenase signature 171 197 9.4E-84 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TSH58p_24770 34f738be82fc28a43e6485a8b8e8de27 435 PRINTS PR00083 Histidinol dehydrogenase signature 363 381 9.4E-84 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TSH58p_24770 34f738be82fc28a43e6485a8b8e8de27 435 PRINTS PR00083 Histidinol dehydrogenase signature 137 163 9.4E-84 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TSH58p_24770 34f738be82fc28a43e6485a8b8e8de27 435 PRINTS PR00083 Histidinol dehydrogenase signature 230 251 9.4E-84 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TSH58p_24770 34f738be82fc28a43e6485a8b8e8de27 435 Gene3D G3DSA:3.40.50.1980 31 233 4.8E-124 T 14-10-2018 TSH58p_24770 34f738be82fc28a43e6485a8b8e8de27 435 Gene3D G3DSA:3.40.50.1980 234 351 4.8E-124 T 14-10-2018 TSH58p_24770 34f738be82fc28a43e6485a8b8e8de27 435 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 34 428 7.0E-159 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TSH58p_09360 71c72cbb8655cdec26f4d8dd3be30b4b 134 Pfam PF05099 Tellurite resistance protein TerB 5 118 1.6E-7 T 14-10-2018 IPR007791 Co-chaperone DjlA, N-terminal TSH58p_09360 71c72cbb8655cdec26f4d8dd3be30b4b 134 Gene3D G3DSA:1.10.3680.10 3 118 1.1E-16 T 14-10-2018 IPR029024 TerB-like TSH58p_09360 71c72cbb8655cdec26f4d8dd3be30b4b 134 SUPERFAMILY SSF158682 5 120 1.96E-13 T 14-10-2018 IPR029024 TerB-like TSH58p_02535 603f94f07578bcd46a1a2091597d3ca6 662 ProSitePatterns PS01303 BCCT family of transporters signature. 308 317 - T 14-10-2018 IPR018093 BCCT transporter, conserved site TSH58p_02535 603f94f07578bcd46a1a2091597d3ca6 662 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 8 488 1.9E-194 T 14-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 TSH58p_02535 603f94f07578bcd46a1a2091597d3ca6 662 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 46 488 3.7E-162 T 14-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 TSH58p_25910 7f003254296e7efb6a3c2f47a43f7886 766 SUPERFAMILY SSF51621 440 739 1.07E-92 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSH58p_25910 7f003254296e7efb6a3c2f47a43f7886 766 Gene3D G3DSA:3.20.20.60 426 757 9.0E-94 T 14-10-2018 TSH58p_25910 7f003254296e7efb6a3c2f47a43f7886 766 SUPERFAMILY SSF47831 214 333 5.49E-26 T 14-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 TSH58p_25910 7f003254296e7efb6a3c2f47a43f7886 766 Gene3D G3DSA:3.50.30.10 198 424 3.7E-54 T 14-10-2018 TSH58p_25910 7f003254296e7efb6a3c2f47a43f7886 766 Pfam PF00391 PEP-utilising enzyme, mobile domain 343 415 5.9E-15 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TSH58p_25910 7f003254296e7efb6a3c2f47a43f7886 766 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 638 656 - T 14-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 TSH58p_25910 7f003254296e7efb6a3c2f47a43f7886 766 SUPERFAMILY SSF52009 315 429 2.75E-22 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 TSH58p_25910 7f003254296e7efb6a3c2f47a43f7886 766 SMART SM00065 36 182 1.5E-15 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_25910 7f003254296e7efb6a3c2f47a43f7886 766 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 655 670 4.2E-19 T 14-10-2018 TSH58p_25910 7f003254296e7efb6a3c2f47a43f7886 766 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 638 653 4.2E-19 T 14-10-2018 TSH58p_25910 7f003254296e7efb6a3c2f47a43f7886 766 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 691 703 4.2E-19 T 14-10-2018 TSH58p_25910 7f003254296e7efb6a3c2f47a43f7886 766 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 483 502 4.2E-19 T 14-10-2018 TSH58p_25910 7f003254296e7efb6a3c2f47a43f7886 766 Pfam PF05524 PEP-utilising enzyme, N-terminal 198 316 2.3E-23 T 14-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 TSH58p_25910 7f003254296e7efb6a3c2f47a43f7886 766 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 196 739 1.3E-120 T 14-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 TSH58p_25910 7f003254296e7efb6a3c2f47a43f7886 766 Gene3D G3DSA:1.10.274.10 215 336 3.7E-54 T 14-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 TSH58p_25910 7f003254296e7efb6a3c2f47a43f7886 766 Pfam PF13185 GAF domain 41 171 5.3E-13 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_25910 7f003254296e7efb6a3c2f47a43f7886 766 SUPERFAMILY SSF55781 22 169 1.0E-24 T 14-10-2018 TSH58p_25910 7f003254296e7efb6a3c2f47a43f7886 766 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 444 732 2.4E-88 T 14-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 TSH58p_25910 7f003254296e7efb6a3c2f47a43f7886 766 Gene3D G3DSA:3.30.450.40 19 179 1.7E-33 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_24015 e6f1a69e4fab06d68991873e16951a11 400 SUPERFAMILY SSF53822 28 399 4.52E-93 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_24015 e6f1a69e4fab06d68991873e16951a11 400 Gene3D G3DSA:3.40.50.2300 28 330 1.0E-113 T 14-10-2018 TSH58p_24015 e6f1a69e4fab06d68991873e16951a11 400 Pfam PF13458 Periplasmic binding protein 28 364 1.4E-89 T 14-10-2018 IPR028081 Leucine-binding protein domain TSH58p_24015 e6f1a69e4fab06d68991873e16951a11 400 Gene3D G3DSA:3.40.50.2300 147 279 1.0E-113 T 14-10-2018 TSH58p_29390 800182b947cdd8872241e1b78e7af614 334 Pfam PF00005 ABC transporter 42 193 2.2E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_29390 800182b947cdd8872241e1b78e7af614 334 Gene3D G3DSA:3.40.50.300 14 334 3.6E-96 T 14-10-2018 TSH58p_29390 800182b947cdd8872241e1b78e7af614 334 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 245 329 5.7E-22 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_29390 800182b947cdd8872241e1b78e7af614 334 SUPERFAMILY SSF52540 17 264 2.32E-72 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_29390 800182b947cdd8872241e1b78e7af614 334 SMART SM00382 51 243 4.6E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_29390 800182b947cdd8872241e1b78e7af614 334 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 245 310 3.3E-18 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_29390 800182b947cdd8872241e1b78e7af614 334 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_18250 12538a329096ce3afc6645a3b68da3a8 243 Gene3D G3DSA:3.40.50.150 38 210 2.1E-16 T 14-10-2018 TSH58p_18250 12538a329096ce3afc6645a3b68da3a8 243 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 49 184 9.2E-21 T 14-10-2018 IPR006342 Methyltransferase FkbM TSH58p_18250 12538a329096ce3afc6645a3b68da3a8 243 SUPERFAMILY SSF53335 46 229 9.73E-25 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_18250 12538a329096ce3afc6645a3b68da3a8 243 Pfam PF05050 Methyltransferase FkbM domain 52 207 1.2E-6 T 14-10-2018 IPR006342 Methyltransferase FkbM TSH58p_12120 2872a09d0d954a4511baafe5733d86a8 559 SUPERFAMILY SSF116726 295 370 3.4E-12 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSH58p_12120 2872a09d0d954a4511baafe5733d86a8 559 Pfam PF06826 Predicted Permease Membrane Region 384 555 3.2E-45 T 14-10-2018 IPR006512 YidE/YbjL duplication TSH58p_12120 2872a09d0d954a4511baafe5733d86a8 559 Pfam PF06826 Predicted Permease Membrane Region 21 189 3.7E-35 T 14-10-2018 IPR006512 YidE/YbjL duplication TSH58p_12120 2872a09d0d954a4511baafe5733d86a8 559 SUPERFAMILY SSF116726 217 284 6.54E-10 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSH58p_12120 2872a09d0d954a4511baafe5733d86a8 559 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 26 176 3.8E-33 T 14-10-2018 IPR006512 YidE/YbjL duplication TSH58p_12120 2872a09d0d954a4511baafe5733d86a8 559 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 388 542 5.5E-42 T 14-10-2018 IPR006512 YidE/YbjL duplication TSH58p_12120 2872a09d0d954a4511baafe5733d86a8 559 Pfam PF02080 TrkA-C domain 220 284 6.1E-9 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TSH58p_12120 2872a09d0d954a4511baafe5733d86a8 559 Pfam PF02080 TrkA-C domain 303 365 6.2E-11 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TSH58p_12120 2872a09d0d954a4511baafe5733d86a8 559 Gene3D G3DSA:3.30.70.1450 290 368 3.3E-9 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSH58p_12120 2872a09d0d954a4511baafe5733d86a8 559 Gene3D G3DSA:3.30.70.1450 214 289 5.2E-8 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSH58p_14180 cc0378fedfb537f4d3f71027ebde58b9 220 SUPERFAMILY SSF53474 7 192 4.7E-13 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_14180 cc0378fedfb537f4d3f71027ebde58b9 220 Gene3D G3DSA:3.40.50.1820 6 211 2.0E-11 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_06555 f48319f2538f67cb7cdbf36ecd9e5423 315 TIGRFAM TIGR01932 hflC: HflC protein 144 282 7.1E-43 T 14-10-2018 IPR010200 HflC GO:0016021|GO:0052547 TSH58p_06555 f48319f2538f67cb7cdbf36ecd9e5423 315 PIRSF PIRSF005651 1 287 3.2E-90 T 14-10-2018 IPR010200 HflC GO:0016021|GO:0052547 TSH58p_06555 f48319f2538f67cb7cdbf36ecd9e5423 315 Gene3D G3DSA:3.30.479.30 50 185 2.9E-25 T 14-10-2018 TSH58p_06555 f48319f2538f67cb7cdbf36ecd9e5423 315 SMART SM00244 21 183 1.3E-34 T 14-10-2018 IPR001107 Band 7 domain TSH58p_06555 f48319f2538f67cb7cdbf36ecd9e5423 315 SUPERFAMILY SSF117892 53 190 2.09E-28 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily TSH58p_06555 f48319f2538f67cb7cdbf36ecd9e5423 315 Pfam PF01145 SPFH domain / Band 7 family 25 200 4.0E-31 T 14-10-2018 IPR001107 Band 7 domain TSH58p_06555 f48319f2538f67cb7cdbf36ecd9e5423 315 PRINTS PR00721 Stomatin signature 159 177 1.2E-5 T 14-10-2018 IPR001972 Stomatin family GO:0016020 TSH58p_06555 f48319f2538f67cb7cdbf36ecd9e5423 315 PRINTS PR00721 Stomatin signature 178 199 1.2E-5 T 14-10-2018 IPR001972 Stomatin family GO:0016020 TSH58p_06555 f48319f2538f67cb7cdbf36ecd9e5423 315 PRINTS PR00721 Stomatin signature 76 97 1.2E-5 T 14-10-2018 IPR001972 Stomatin family GO:0016020 TSH58p_13930 bb69bf42c73afed9b8bb1257846a9838 130 Pfam PF00034 Cytochrome c 33 129 4.4E-8 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_13930 bb69bf42c73afed9b8bb1257846a9838 130 Gene3D G3DSA:1.10.760.10 9 127 1.2E-35 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_13930 bb69bf42c73afed9b8bb1257846a9838 130 SUPERFAMILY SSF46626 30 129 2.16E-28 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_13930 bb69bf42c73afed9b8bb1257846a9838 130 PRINTS PR00604 Class IA and IB cytochrome C signature 41 48 5.7E-12 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_13930 bb69bf42c73afed9b8bb1257846a9838 130 PRINTS PR00604 Class IA and IB cytochrome C signature 53 68 5.7E-12 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_13930 bb69bf42c73afed9b8bb1257846a9838 130 PRINTS PR00604 Class IA and IB cytochrome C signature 83 99 5.7E-12 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_13930 bb69bf42c73afed9b8bb1257846a9838 130 PRINTS PR00604 Class IA and IB cytochrome C signature 102 112 5.7E-12 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_13930 bb69bf42c73afed9b8bb1257846a9838 130 PRINTS PR00604 Class IA and IB cytochrome C signature 119 127 5.7E-12 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_13930 bb69bf42c73afed9b8bb1257846a9838 130 PRINTS PR00604 Class IA and IB cytochrome C signature 69 79 5.7E-12 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_21160 2b220f379fcee34f6995e91bb18f4fc0 398 SUPERFAMILY SSF53187 14 390 4.86E-60 T 14-10-2018 TSH58p_21160 2b220f379fcee34f6995e91bb18f4fc0 398 Gene3D G3DSA:3.40.630.10 24 380 4.7E-102 T 14-10-2018 TSH58p_21160 2b220f379fcee34f6995e91bb18f4fc0 398 Pfam PF01546 Peptidase family M20/M25/M40 79 390 2.7E-34 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 TSH58p_21160 2b220f379fcee34f6995e91bb18f4fc0 398 SUPERFAMILY SSF55031 187 293 5.53E-19 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TSH58p_21160 2b220f379fcee34f6995e91bb18f4fc0 398 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 19 390 4.0E-115 T 14-10-2018 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 TSH58p_21160 2b220f379fcee34f6995e91bb18f4fc0 398 Gene3D G3DSA:3.30.70.360 187 303 4.7E-102 T 14-10-2018 TSH58p_21160 2b220f379fcee34f6995e91bb18f4fc0 398 Pfam PF07687 Peptidase dimerisation domain 183 295 6.0E-19 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain TSH58p_32555 8a52be3c4d0f296c310ea0e578feecff 352 Gene3D G3DSA:3.10.310.10 167 336 3.9E-119 T 14-10-2018 TSH58p_32555 8a52be3c4d0f296c310ea0e578feecff 352 SUPERFAMILY SSF54506 5 168 3.53E-63 T 14-10-2018 TSH58p_32555 8a52be3c4d0f296c310ea0e578feecff 352 Gene3D G3DSA:3.10.310.10 6 350 3.9E-119 T 14-10-2018 TSH58p_32555 8a52be3c4d0f296c310ea0e578feecff 352 Pfam PF04303 PrpF protein 6 351 5.3E-117 T 14-10-2018 IPR007400 PrpF protein TSH58p_32555 8a52be3c4d0f296c310ea0e578feecff 352 SUPERFAMILY SSF54506 172 351 4.39E-58 T 14-10-2018 TSH58p_05655 20dbe6c2d94c84129b712adf623856ea 405 SUPERFAMILY SSF63882 1 174 5.1E-53 T 14-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_05655 20dbe6c2d94c84129b712adf623856ea 405 Gene3D G3DSA:2.170.190.11 44 140 8.6E-119 T 14-10-2018 TSH58p_05655 20dbe6c2d94c84129b712adf623856ea 405 Pfam PF03453 MoeA N-terminal region (domain I and II) 3 165 5.1E-42 T 14-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_05655 20dbe6c2d94c84129b712adf623856ea 405 Pfam PF00994 Probable molybdopterin binding domain 179 313 2.6E-17 T 14-10-2018 IPR001453 MoaB/Mog domain TSH58p_05655 20dbe6c2d94c84129b712adf623856ea 405 SUPERFAMILY SSF53218 176 318 1.57E-34 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSH58p_05655 20dbe6c2d94c84129b712adf623856ea 405 Pfam PF03454 MoeA C-terminal region (domain IV) 327 398 9.5E-17 T 14-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_05655 20dbe6c2d94c84129b712adf623856ea 405 SMART SM00852 179 314 6.7E-32 T 14-10-2018 IPR001453 MoaB/Mog domain TSH58p_05655 20dbe6c2d94c84129b712adf623856ea 405 Gene3D G3DSA:3.40.980.10 174 322 8.6E-119 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSH58p_05655 20dbe6c2d94c84129b712adf623856ea 405 SUPERFAMILY SSF63867 324 400 5.63E-19 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_05655 20dbe6c2d94c84129b712adf623856ea 405 Gene3D G3DSA:2.40.340.10 323 393 8.6E-119 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_05655 20dbe6c2d94c84129b712adf623856ea 405 Gene3D G3DSA:3.90.105.10 21 173 8.6E-119 T 14-10-2018 TSH58p_28065 a83f5b97077d11aee8adc220305c6abd 334 Pfam PF00753 Metallo-beta-lactamase superfamily 97 290 1.5E-19 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_28065 a83f5b97077d11aee8adc220305c6abd 334 SUPERFAMILY SSF56281 39 325 1.11E-55 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_28065 a83f5b97077d11aee8adc220305c6abd 334 Gene3D G3DSA:3.60.15.10 37 331 9.0E-107 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_28065 a83f5b97077d11aee8adc220305c6abd 334 SMART SM00849 98 304 1.4E-17 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_28865 aef238e8133f9d6ae2650ec19ba1daea 99 Gene3D G3DSA:2.60.120.10 4 97 2.0E-26 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_28865 aef238e8133f9d6ae2650ec19ba1daea 99 Pfam PF07883 Cupin domain 23 93 3.6E-9 T 14-10-2018 IPR013096 Cupin 2, conserved barrel TSH58p_28865 aef238e8133f9d6ae2650ec19ba1daea 99 SUPERFAMILY SSF51182 7 93 1.04E-15 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_12455 04c208c5a559d79739b1c385f7cb2cd3 646 Gene3D G3DSA:3.40.50.300 219 351 8.1E-41 T 14-10-2018 TSH58p_12455 04c208c5a559d79739b1c385f7cb2cd3 646 SUPERFAMILY SSF47819 570 644 1.61E-22 T 14-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 TSH58p_12455 04c208c5a559d79739b1c385f7cb2cd3 646 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 25 475 2.4E-153 T 14-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 TSH58p_12455 04c208c5a559d79739b1c385f7cb2cd3 646 Pfam PF00570 HRDC domain 576 642 3.7E-21 T 14-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 TSH58p_12455 04c208c5a559d79739b1c385f7cb2cd3 646 Gene3D G3DSA:1.10.150.80 571 645 6.0E-22 T 14-10-2018 TSH58p_12455 04c208c5a559d79739b1c385f7cb2cd3 646 Pfam PF16124 RecQ zinc-binding 354 416 1.0E-19 T 14-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain TSH58p_12455 04c208c5a559d79739b1c385f7cb2cd3 646 SUPERFAMILY SSF52540 22 207 1.07E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_12455 04c208c5a559d79739b1c385f7cb2cd3 646 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 25 644 3.4E-239 T 14-10-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 TSH58p_12455 04c208c5a559d79739b1c385f7cb2cd3 646 Pfam PF00271 Helicase conserved C-terminal domain 236 341 2.8E-16 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_12455 04c208c5a559d79739b1c385f7cb2cd3 646 SMART SM00487 32 228 5.9E-29 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSH58p_12455 04c208c5a559d79739b1c385f7cb2cd3 646 SMART SM00956 423 526 2.9E-52 T 14-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 TSH58p_12455 04c208c5a559d79739b1c385f7cb2cd3 646 Gene3D G3DSA:3.40.50.300 16 218 2.3E-81 T 14-10-2018 TSH58p_12455 04c208c5a559d79739b1c385f7cb2cd3 646 SMART SM00341 572 645 6.4E-14 T 14-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 TSH58p_12455 04c208c5a559d79739b1c385f7cb2cd3 646 Pfam PF00270 DEAD/DEAH box helicase 40 197 1.7E-17 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TSH58p_12455 04c208c5a559d79739b1c385f7cb2cd3 646 Gene3D G3DSA:1.10.10.10 352 537 1.8E-51 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_12455 04c208c5a559d79739b1c385f7cb2cd3 646 Pfam PF09382 RQC domain 418 527 9.3E-40 T 14-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 TSH58p_12455 04c208c5a559d79739b1c385f7cb2cd3 646 SMART SM00490 261 342 5.4E-27 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_12455 04c208c5a559d79739b1c385f7cb2cd3 646 SUPERFAMILY SSF52540 218 465 1.59E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_16300 3ff29ebcc8db33acbc10d1c5235c0e4b 240 Pfam PF01618 MotA/TolQ/ExbB proton channel family 89 220 4.6E-40 T 14-10-2018 IPR002898 MotA/TolQ/ExbB proton channel TSH58p_16300 3ff29ebcc8db33acbc10d1c5235c0e4b 240 TIGRFAM TIGR02796 tolQ: protein TolQ 20 232 4.4E-84 T 14-10-2018 IPR014163 Tol-Pal system, TolQ GO:0016021|GO:0043213 TSH58p_16300 3ff29ebcc8db33acbc10d1c5235c0e4b 240 Hamap MF_02202 Tol-Pal system protein TolQ [tolQ]. 18 237 38.601 T 14-10-2018 IPR014163 Tol-Pal system, TolQ GO:0016021|GO:0043213 TSH58p_32185 9a612e19f5398df3e5d52fce77df2e77 182 TIGRFAM TIGR00077 lspA: signal peptidase II 26 167 8.4E-31 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TSH58p_32185 9a612e19f5398df3e5d52fce77df2e77 182 ProSitePatterns PS00855 Signal peptidases II signature. 111 123 - T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TSH58p_32185 9a612e19f5398df3e5d52fce77df2e77 182 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 15 169 14.091 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TSH58p_32185 9a612e19f5398df3e5d52fce77df2e77 182 Pfam PF01252 Signal peptidase (SPase) II 25 162 9.5E-32 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TSH58p_32185 9a612e19f5398df3e5d52fce77df2e77 182 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 144 160 2.3E-14 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TSH58p_32185 9a612e19f5398df3e5d52fce77df2e77 182 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 62 70 2.3E-14 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TSH58p_32185 9a612e19f5398df3e5d52fce77df2e77 182 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 108 123 2.3E-14 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TSH58p_05245 2a35aa1254fbf6cfab0f22adb1d0bc60 321 Gene3D G3DSA:3.40.190.90 123 287 2.2E-132 T 14-10-2018 TSH58p_05245 2a35aa1254fbf6cfab0f22adb1d0bc60 321 Gene3D G3DSA:3.30.540.10 5 312 2.2E-132 T 14-10-2018 TSH58p_05245 2a35aa1254fbf6cfab0f22adb1d0bc60 321 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 1 320 7.7E-109 T 14-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 TSH58p_05245 2a35aa1254fbf6cfab0f22adb1d0bc60 321 PIRSF PIRSF004532 1 321 7.0E-140 T 14-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 TSH58p_05245 2a35aa1254fbf6cfab0f22adb1d0bc60 321 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 3 312 5.3E-139 T 14-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 TSH58p_05245 2a35aa1254fbf6cfab0f22adb1d0bc60 321 SUPERFAMILY SSF56655 1 315 1.68E-108 T 14-10-2018 TSH58p_11250 9c5ca55ba1bf5b5fab9116d39ce9c260 215 Gene3D G3DSA:1.10.1670.10 11 203 6.0E-75 T 14-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 TSH58p_11250 9c5ca55ba1bf5b5fab9116d39ce9c260 215 TIGRFAM TIGR01083 nth: endonuclease III 6 194 1.2E-80 T 14-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 TSH58p_11250 9c5ca55ba1bf5b5fab9116d39ce9c260 215 Hamap MF_00942 Endonuclease III [nth]. 1 209 37.014 T 14-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 TSH58p_11250 9c5ca55ba1bf5b5fab9116d39ce9c260 215 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 14-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 TSH58p_11250 9c5ca55ba1bf5b5fab9116d39ce9c260 215 Pfam PF00633 Helix-hairpin-helix motif 100 127 1.1E-8 T 14-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 TSH58p_11250 9c5ca55ba1bf5b5fab9116d39ce9c260 215 Gene3D G3DSA:1.10.340.30 21 132 6.0E-75 T 14-10-2018 TSH58p_11250 9c5ca55ba1bf5b5fab9116d39ce9c260 215 SUPERFAMILY SSF48150 6 207 1.35E-69 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TSH58p_11250 9c5ca55ba1bf5b5fab9116d39ce9c260 215 SMART SM00525 186 206 2.9E-4 T 14-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 TSH58p_11250 9c5ca55ba1bf5b5fab9116d39ce9c260 215 SMART SM00478 38 185 2.0E-50 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TSH58p_11250 9c5ca55ba1bf5b5fab9116d39ce9c260 215 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 168 2.2E-19 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TSH58p_11250 9c5ca55ba1bf5b5fab9116d39ce9c260 215 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 187 203 1.5E-5 T 14-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 TSH58p_11250 9c5ca55ba1bf5b5fab9116d39ce9c260 215 PIRSF PIRSF001435 2 209 2.2E-47 T 14-10-2018 TSH58p_30475 06111e4ba7f1c38aa0085cc579ec5235 327 SUPERFAMILY SSF51556 9 321 6.05E-79 T 14-10-2018 IPR032466 Metal-dependent hydrolase TSH58p_30475 06111e4ba7f1c38aa0085cc579ec5235 327 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 20 318 6.7E-87 T 14-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 TSH58p_30475 06111e4ba7f1c38aa0085cc579ec5235 327 Gene3D G3DSA:3.20.20.140 1 323 1.6E-112 T 14-10-2018 TSH58p_05210 e88207246ab23a139f0fa388bfdc0d09 309 PRINTS PR01270 Histone deacetylase superfamily signature 155 170 1.9E-16 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSH58p_05210 e88207246ab23a139f0fa388bfdc0d09 309 PRINTS PR01270 Histone deacetylase superfamily signature 121 144 1.9E-16 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSH58p_05210 e88207246ab23a139f0fa388bfdc0d09 309 PRINTS PR01270 Histone deacetylase superfamily signature 236 246 1.9E-16 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSH58p_05210 e88207246ab23a139f0fa388bfdc0d09 309 Gene3D G3DSA:3.40.800.20 1 308 5.6E-115 T 14-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSH58p_05210 e88207246ab23a139f0fa388bfdc0d09 309 SUPERFAMILY SSF52768 1 307 2.4E-104 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily TSH58p_05210 e88207246ab23a139f0fa388bfdc0d09 309 Pfam PF00850 Histone deacetylase domain 20 306 7.7E-86 T 14-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSH58p_09145 5a0a85d4743d7fc32054ad9c19eec3ae 267 Gene3D G3DSA:3.40.50.1820 16 265 1.7E-64 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_09145 5a0a85d4743d7fc32054ad9c19eec3ae 267 Pfam PF12146 Serine aminopeptidase, S33 66 150 6.9E-10 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 TSH58p_09145 5a0a85d4743d7fc32054ad9c19eec3ae 267 SUPERFAMILY SSF53474 22 261 2.59E-39 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_16550 b84aa85def58a216ce3a634bcbdcfe0c 826 Pfam PF08494 DEAD/H associated 593 774 1.5E-44 T 14-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 TSH58p_16550 b84aa85def58a216ce3a634bcbdcfe0c 826 Pfam PF00270 DEAD/DEAH box helicase 26 194 8.4E-23 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TSH58p_16550 b84aa85def58a216ce3a634bcbdcfe0c 826 SMART SM00487 20 229 1.1E-27 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSH58p_16550 b84aa85def58a216ce3a634bcbdcfe0c 826 Gene3D G3DSA:3.40.50.300 232 376 3.1E-25 T 14-10-2018 TSH58p_16550 b84aa85def58a216ce3a634bcbdcfe0c 826 SMART SM00490 270 355 5.2E-14 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_16550 b84aa85def58a216ce3a634bcbdcfe0c 826 PIRSF PIRSF037307 5 818 9.3E-197 T 14-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 TSH58p_16550 b84aa85def58a216ce3a634bcbdcfe0c 826 TIGRFAM TIGR04121 DEXH_lig_assoc: DEXH box helicase, DNA ligase-associated 12 802 0.0 T 14-10-2018 IPR026362 DEXH box helicase, DNA ligase-associated TSH58p_16550 b84aa85def58a216ce3a634bcbdcfe0c 826 Pfam PF00271 Helicase conserved C-terminal domain 249 350 7.8E-16 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_16550 b84aa85def58a216ce3a634bcbdcfe0c 826 SUPERFAMILY SSF52540 34 361 2.62E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_16550 b84aa85def58a216ce3a634bcbdcfe0c 826 Gene3D G3DSA:3.40.50.300 14 209 9.3E-46 T 14-10-2018 TSH58p_28155 c971b999cbb2b9ef4b5512ef3abf38d0 162 Gene3D G3DSA:2.60.120.10 16 125 2.0E-30 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_28155 c971b999cbb2b9ef4b5512ef3abf38d0 162 Pfam PF05899 Protein of unknown function (DUF861) 52 123 8.6E-22 T 14-10-2018 IPR008579 Domain of unknown function DUF861, cupin-3 KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 TSH58p_28155 c971b999cbb2b9ef4b5512ef3abf38d0 162 SUPERFAMILY SSF51182 29 125 1.6E-18 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_21150 bd033bb6be3a0590ff18a79319cd18b6 329 SMART SM00382 34 233 5.2E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_21150 bd033bb6be3a0590ff18a79319cd18b6 329 SUPERFAMILY SSF52540 5 254 1.7E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_21150 bd033bb6be3a0590ff18a79319cd18b6 329 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 299 3.1E-19 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_21150 bd033bb6be3a0590ff18a79319cd18b6 329 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 317 6.9E-25 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_21150 bd033bb6be3a0590ff18a79319cd18b6 329 Gene3D G3DSA:3.40.50.300 3 325 1.7E-97 T 14-10-2018 TSH58p_21150 bd033bb6be3a0590ff18a79319cd18b6 329 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_21150 bd033bb6be3a0590ff18a79319cd18b6 329 Pfam PF00005 ABC transporter 26 183 3.1E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_03995 cacb77542904d1e7e7df54895e134a48 196 ProSitePatterns PS00893 Nudix box signature. 81 102 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TSH58p_03995 cacb77542904d1e7e7df54895e134a48 196 Pfam PF00293 NUDIX domain 51 170 2.5E-13 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TSH58p_03995 cacb77542904d1e7e7df54895e134a48 196 Gene3D G3DSA:3.90.79.10 5 191 3.3E-33 T 14-10-2018 TSH58p_03995 cacb77542904d1e7e7df54895e134a48 196 SUPERFAMILY SSF55811 5 174 3.25E-27 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TSH58p_15740 4ddadb6ddc081c2476bbdeb93c31d764 289 Pfam PF01569 PAP2 superfamily 150 224 2.1E-9 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase TSH58p_15740 4ddadb6ddc081c2476bbdeb93c31d764 289 SUPERFAMILY SSF48317 75 229 8.18E-12 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily TSH58p_15740 4ddadb6ddc081c2476bbdeb93c31d764 289 Gene3D G3DSA:1.20.144.10 144 235 1.0E-12 T 14-10-2018 TSH58p_13060 b9c1a8ff178d3d768b4a79b0b383e2c4 443 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 337 435 1.5E-8 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_13060 b9c1a8ff178d3d768b4a79b0b383e2c4 443 SUPERFAMILY SSF47384 216 280 4.51E-6 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_13060 b9c1a8ff178d3d768b4a79b0b383e2c4 443 Gene3D G3DSA:1.10.287.130 215 283 4.9E-9 T 14-10-2018 TSH58p_13060 b9c1a8ff178d3d768b4a79b0b383e2c4 443 SUPERFAMILY SSF55874 297 435 3.8E-20 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_13060 b9c1a8ff178d3d768b4a79b0b383e2c4 443 SMART SM00387 331 438 1.2E-13 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_13060 b9c1a8ff178d3d768b4a79b0b383e2c4 443 Gene3D G3DSA:3.30.565.10 292 438 3.0E-15 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_27985 ef5a59d84b65f67f2591088d7014362d 262 SUPERFAMILY SSF51206 140 244 5.76E-24 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like TSH58p_27985 ef5a59d84b65f67f2591088d7014362d 262 Gene3D G3DSA:2.60.120.10 9 124 3.5E-26 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_27985 ef5a59d84b65f67f2591088d7014362d 262 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 191 208 - T 14-10-2018 IPR018488 Cyclic nucleotide-binding, conserved site TSH58p_27985 ef5a59d84b65f67f2591088d7014362d 262 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 63 80 - T 14-10-2018 IPR018488 Cyclic nucleotide-binding, conserved site TSH58p_27985 ef5a59d84b65f67f2591088d7014362d 262 Gene3D G3DSA:2.60.120.10 133 246 4.5E-26 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_27985 ef5a59d84b65f67f2591088d7014362d 262 Pfam PF00027 Cyclic nucleotide-binding domain 15 97 6.4E-20 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_27985 ef5a59d84b65f67f2591088d7014362d 262 Pfam PF00027 Cyclic nucleotide-binding domain 147 227 8.2E-19 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_27985 ef5a59d84b65f67f2591088d7014362d 262 PRINTS PR00103 cAMP-dependent protein kinase signature 17 31 6.5E-9 T 14-10-2018 TSH58p_27985 ef5a59d84b65f67f2591088d7014362d 262 PRINTS PR00103 cAMP-dependent protein kinase signature 201 212 6.5E-9 T 14-10-2018 TSH58p_27985 ef5a59d84b65f67f2591088d7014362d 262 PRINTS PR00103 cAMP-dependent protein kinase signature 189 198 6.5E-9 T 14-10-2018 TSH58p_27985 ef5a59d84b65f67f2591088d7014362d 262 PRINTS PR00103 cAMP-dependent protein kinase signature 32 46 6.5E-9 T 14-10-2018 TSH58p_27985 ef5a59d84b65f67f2591088d7014362d 262 SMART SM00100 1 113 9.2E-6 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_27985 ef5a59d84b65f67f2591088d7014362d 262 SMART SM00100 121 241 2.1E-12 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_27985 ef5a59d84b65f67f2591088d7014362d 262 SUPERFAMILY SSF51206 14 120 2.88E-22 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like TSH58p_25815 c59fd4eadc98bb458795ebe534a97277 222 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 77 1.9E-12 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 TSH58p_25815 c59fd4eadc98bb458795ebe534a97277 222 SUPERFAMILY SSF52833 1 101 2.11E-18 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_25815 c59fd4eadc98bb458795ebe534a97277 222 Gene3D G3DSA:3.40.30.10 4 222 6.1E-83 T 14-10-2018 TSH58p_25815 c59fd4eadc98bb458795ebe534a97277 222 Pfam PF00043 Glutathione S-transferase, C-terminal domain 145 198 1.3E-8 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal TSH58p_25815 c59fd4eadc98bb458795ebe534a97277 222 Gene3D G3DSA:1.20.1050.10 79 197 6.1E-83 T 14-10-2018 TSH58p_25815 c59fd4eadc98bb458795ebe534a97277 222 SUPERFAMILY SSF47616 70 216 4.55E-24 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily TSH58p_27190 cb1c37c64908dc5444d7a9ba74b4d4f2 420 Gene3D G3DSA:1.10.490.140 344 405 6.9E-7 T 14-10-2018 TSH58p_27190 cb1c37c64908dc5444d7a9ba74b4d4f2 420 Gene3D G3DSA:1.10.490.140 163 272 3.6E-20 T 14-10-2018 TSH58p_27190 cb1c37c64908dc5444d7a9ba74b4d4f2 420 TIGRFAM TIGR00702 TIGR00702: YcaO-type kinase domain 32 400 7.3E-66 T 14-10-2018 IPR003776 YcaO-like domain TSH58p_27190 cb1c37c64908dc5444d7a9ba74b4d4f2 420 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 80 400 2.1E-81 T 14-10-2018 IPR003776 YcaO-like domain TSH58p_05710 96ad72d8ed2eedffb46fec1f52708038 280 Gene3D G3DSA:3.40.140.80 134 278 1.7E-54 T 14-10-2018 TSH58p_05710 96ad72d8ed2eedffb46fec1f52708038 280 Gene3D G3DSA:3.40.50.20 4 133 3.6E-40 T 14-10-2018 TSH58p_05710 96ad72d8ed2eedffb46fec1f52708038 280 Pfam PF06230 Protein of unknown function (DUF1009) 60 270 1.1E-74 T 14-10-2018 IPR010415 Protein of unknown function DUF1009 KEGG: 00540+3.6.1.54 TSH58p_05555 92191df2b7a5a96a429a14ddd6b28b8d 100 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 30 98 2.2E-8 T 14-10-2018 IPR008792 Coenzyme PQQ synthesis D TSH58p_05555 92191df2b7a5a96a429a14ddd6b28b8d 100 Gene3D G3DSA:1.10.10.1150 2 99 3.2E-26 T 14-10-2018 TSH58p_03080 c739251411a932b0b5443e4c2bf02e58 391 Pfam PF01757 Acyltransferase family 26 352 1.8E-14 T 14-10-2018 IPR002656 Acyltransferase 3 GO:0016747 TSH58p_13235 d628f1fee248b5ba391c1680dd53098b 198 Gene3D G3DSA:2.20.70.10 22 48 4.5E-5 T 14-10-2018 TSH58p_13235 d628f1fee248b5ba391c1680dd53098b 198 Pfam PF14803 Nudix N-terminal 25 48 1.3E-7 T 14-10-2018 IPR029401 Nudix hydrolase, N-terminal KEGG: 00230+3.6.1.13|KEGG: 00740+3.6.1.18 TSH58p_13235 d628f1fee248b5ba391c1680dd53098b 198 Gene3D G3DSA:3.90.79.10 49 184 3.4E-36 T 14-10-2018 TSH58p_13235 d628f1fee248b5ba391c1680dd53098b 198 Pfam PF00293 NUDIX domain 57 153 2.8E-10 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TSH58p_13235 d628f1fee248b5ba391c1680dd53098b 198 SUPERFAMILY SSF55811 27 175 3.11E-34 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TSH58p_13030 6688dbac8773bddec5d121fcc7536300 757 Gene3D G3DSA:3.40.50.300 487 757 7.6E-66 T 14-10-2018 TSH58p_13030 6688dbac8773bddec5d121fcc7536300 757 Pfam PF02706 Chain length determinant protein 38 122 1.0E-11 T 14-10-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 TSH58p_13030 6688dbac8773bddec5d121fcc7536300 757 Pfam PF13807 G-rich domain on putative tyrosine kinase 417 492 1.6E-13 T 14-10-2018 IPR032807 Tyrosine kinase, G-rich domain TSH58p_13030 6688dbac8773bddec5d121fcc7536300 757 SUPERFAMILY SSF52540 561 741 3.2E-33 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_13030 6688dbac8773bddec5d121fcc7536300 757 Pfam PF13614 AAA domain 561 718 1.9E-8 T 14-10-2018 IPR025669 AAA domain TSH58p_22880 c2a3349bb6e25eba26537bcf12ccbbbc 298 SMART SM00448 1 114 3.6E-14 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_22880 c2a3349bb6e25eba26537bcf12ccbbbc 298 SMART SM00267 120 295 2.7E-57 T 14-10-2018 IPR000160 GGDEF domain TSH58p_22880 c2a3349bb6e25eba26537bcf12ccbbbc 298 Gene3D G3DSA:3.40.50.2300 1 117 4.3E-23 T 14-10-2018 TSH58p_22880 c2a3349bb6e25eba26537bcf12ccbbbc 298 Gene3D G3DSA:3.30.70.270 118 295 3.6E-59 T 14-10-2018 TSH58p_22880 c2a3349bb6e25eba26537bcf12ccbbbc 298 SUPERFAMILY SSF55073 136 294 7.14E-47 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_22880 c2a3349bb6e25eba26537bcf12ccbbbc 298 Pfam PF00990 Diguanylate cyclase, GGDEF domain 131 291 5.2E-44 T 14-10-2018 IPR000160 GGDEF domain TSH58p_22880 c2a3349bb6e25eba26537bcf12ccbbbc 298 SUPERFAMILY SSF52172 1 132 2.42E-27 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_22880 c2a3349bb6e25eba26537bcf12ccbbbc 298 Pfam PF00072 Response regulator receiver domain 3 114 3.1E-14 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_22880 c2a3349bb6e25eba26537bcf12ccbbbc 298 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 127 294 1.7E-51 T 14-10-2018 IPR000160 GGDEF domain TSH58p_07095 0f8bee0c6fe4b03f7c71a46693b74860 306 SUPERFAMILY SSF46785 6 88 1.12E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_07095 0f8bee0c6fe4b03f7c71a46693b74860 306 Gene3D G3DSA:3.40.190.10 93 292 8.7E-52 T 14-10-2018 TSH58p_07095 0f8bee0c6fe4b03f7c71a46693b74860 306 Gene3D G3DSA:1.10.10.10 4 87 6.5E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_07095 0f8bee0c6fe4b03f7c71a46693b74860 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 2.1E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_07095 0f8bee0c6fe4b03f7c71a46693b74860 306 Gene3D G3DSA:3.40.190.10 165 267 8.7E-52 T 14-10-2018 TSH58p_07095 0f8bee0c6fe4b03f7c71a46693b74860 306 Pfam PF03466 LysR substrate binding domain 89 295 2.8E-38 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_07095 0f8bee0c6fe4b03f7c71a46693b74860 306 SUPERFAMILY SSF53850 91 297 3.08E-40 T 14-10-2018 TSH58p_07095 0f8bee0c6fe4b03f7c71a46693b74860 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 3.0E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_07095 0f8bee0c6fe4b03f7c71a46693b74860 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 3.0E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_07095 0f8bee0c6fe4b03f7c71a46693b74860 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 3.0E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_12940 3eb35dc270ea80506cfe6204d9577d18 579 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 5 574 22.439 T 14-10-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0032977 TSH58p_12940 3eb35dc270ea80506cfe6204d9577d18 579 PRINTS PR00701 60kDa inner membrane protein signature 345 365 2.3E-21 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 TSH58p_12940 3eb35dc270ea80506cfe6204d9577d18 579 PRINTS PR00701 60kDa inner membrane protein signature 436 459 2.3E-21 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 TSH58p_12940 3eb35dc270ea80506cfe6204d9577d18 579 PRINTS PR00701 60kDa inner membrane protein signature 2 23 2.3E-21 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 TSH58p_12940 3eb35dc270ea80506cfe6204d9577d18 579 PRINTS PR00701 60kDa inner membrane protein signature 92 113 2.3E-21 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 TSH58p_12940 3eb35dc270ea80506cfe6204d9577d18 579 PRINTS PR00701 60kDa inner membrane protein signature 264 279 2.3E-21 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 TSH58p_12940 3eb35dc270ea80506cfe6204d9577d18 579 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 374 572 1.2E-69 T 14-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_12940 3eb35dc270ea80506cfe6204d9577d18 579 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 4 372 2.7E-96 T 14-10-2018 IPR028053 Membrane insertase YidC, N-terminal TSH58p_12940 3eb35dc270ea80506cfe6204d9577d18 579 Pfam PF14849 YidC periplasmic domain 86 363 3.8E-83 T 14-10-2018 IPR038210 Membrane insertase YidC, periplasmic domain TSH58p_12940 3eb35dc270ea80506cfe6204d9577d18 579 Pfam PF02096 60Kd inner membrane protein 375 572 4.0E-60 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 TSH58p_12940 3eb35dc270ea80506cfe6204d9577d18 579 PRINTS PR01900 YidC translocation/secretion protein signature 360 376 9.8E-22 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 TSH58p_12940 3eb35dc270ea80506cfe6204d9577d18 579 PRINTS PR01900 YidC translocation/secretion protein signature 508 523 9.8E-22 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 TSH58p_12940 3eb35dc270ea80506cfe6204d9577d18 579 PRINTS PR01900 YidC translocation/secretion protein signature 527 551 9.8E-22 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 TSH58p_12940 3eb35dc270ea80506cfe6204d9577d18 579 Gene3D G3DSA:2.70.98.90 82 353 5.3E-39 T 14-10-2018 IPR038221 YidC, periplasmic domain superfamily TSH58p_11600 ab49c56d2498bf9158a0700ecb42281a 472 Pfam PF07731 Multicopper oxidase 375 471 3.1E-26 T 14-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 TSH58p_11600 ab49c56d2498bf9158a0700ecb42281a 472 SUPERFAMILY SSF49503 322 470 3.45E-30 T 14-10-2018 IPR008972 Cupredoxin TSH58p_11600 ab49c56d2498bf9158a0700ecb42281a 472 SUPERFAMILY SSF49503 48 178 3.29E-36 T 14-10-2018 IPR008972 Cupredoxin TSH58p_11600 ab49c56d2498bf9158a0700ecb42281a 472 Gene3D G3DSA:2.60.40.420 319 471 1.1E-41 T 14-10-2018 IPR008972 Cupredoxin TSH58p_11600 ab49c56d2498bf9158a0700ecb42281a 472 Pfam PF00394 Multicopper oxidase 169 281 5.5E-11 T 14-10-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 TSH58p_11600 ab49c56d2498bf9158a0700ecb42281a 472 Gene3D G3DSA:2.60.40.420 167 298 3.8E-33 T 14-10-2018 IPR008972 Cupredoxin TSH58p_11600 ab49c56d2498bf9158a0700ecb42281a 472 Pfam PF07732 Multicopper oxidase 55 160 1.3E-35 T 14-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 TSH58p_11600 ab49c56d2498bf9158a0700ecb42281a 472 ProSitePatterns PS00080 Multicopper oxidases signature 2. 453 464 - T 14-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 TSH58p_11600 ab49c56d2498bf9158a0700ecb42281a 472 SUPERFAMILY SSF49503 161 320 4.18E-20 T 14-10-2018 IPR008972 Cupredoxin TSH58p_11600 ab49c56d2498bf9158a0700ecb42281a 472 ProSitePatterns PS00079 Multicopper oxidases signature 1. 448 468 - T 14-10-2018 IPR033138 Multicopper oxidases, conserved site TSH58p_11600 ab49c56d2498bf9158a0700ecb42281a 472 Gene3D G3DSA:2.60.40.420 34 166 7.9E-43 T 14-10-2018 IPR008972 Cupredoxin TSH58p_27520 fb63ff587ea6c21dc0de08e64d3d3b42 281 PRINTS PR00996 Glutamate methyltransferase family signature 104 124 9.8E-39 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_27520 fb63ff587ea6c21dc0de08e64d3d3b42 281 PRINTS PR00996 Glutamate methyltransferase family signature 25 38 9.8E-39 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_27520 fb63ff587ea6c21dc0de08e64d3d3b42 281 PRINTS PR00996 Glutamate methyltransferase family signature 226 249 9.8E-39 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_27520 fb63ff587ea6c21dc0de08e64d3d3b42 281 PRINTS PR00996 Glutamate methyltransferase family signature 139 155 9.8E-39 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_27520 fb63ff587ea6c21dc0de08e64d3d3b42 281 PRINTS PR00996 Glutamate methyltransferase family signature 207 221 9.8E-39 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_27520 fb63ff587ea6c21dc0de08e64d3d3b42 281 PRINTS PR00996 Glutamate methyltransferase family signature 64 76 9.8E-39 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_27520 fb63ff587ea6c21dc0de08e64d3d3b42 281 Pfam PF03705 CheR methyltransferase, all-alpha domain 4 55 6.3E-9 T 14-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal TSH58p_27520 fb63ff587ea6c21dc0de08e64d3d3b42 281 Pfam PF01739 CheR methyltransferase, SAM binding domain 71 263 3.8E-64 T 14-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal TSH58p_27520 fb63ff587ea6c21dc0de08e64d3d3b42 281 Gene3D G3DSA:1.10.155.10 1 69 2.3E-6 T 14-10-2018 IPR036804 Chemotaxis receptor methyltransferase CheR, N-terminal domain superfamily TSH58p_27520 fb63ff587ea6c21dc0de08e64d3d3b42 281 Gene3D G3DSA:3.40.50.150 70 268 2.6E-58 T 14-10-2018 TSH58p_27520 fb63ff587ea6c21dc0de08e64d3d3b42 281 SUPERFAMILY SSF47757 4 70 3.79E-13 T 14-10-2018 TSH58p_27520 fb63ff587ea6c21dc0de08e64d3d3b42 281 SMART SM00138 3 267 5.5E-117 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_27520 fb63ff587ea6c21dc0de08e64d3d3b42 281 SUPERFAMILY SSF53335 71 264 7.94E-50 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_13355 64c7c021ed3f545f604a3b1c5761f900 451 Pfam PF04055 Radical SAM superfamily 54 222 1.8E-21 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSH58p_13355 64c7c021ed3f545f604a3b1c5761f900 451 Gene3D G3DSA:1.10.10.920 361 451 4.7E-17 T 14-10-2018 TSH58p_13355 64c7c021ed3f545f604a3b1c5761f900 451 Gene3D G3DSA:3.80.30.20 1 360 1.8E-108 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TSH58p_13355 64c7c021ed3f545f604a3b1c5761f900 451 PIRSF PIRSF000167 1 451 9.4E-162 T 14-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 TSH58p_13355 64c7c021ed3f545f604a3b1c5761f900 451 SMART SM00729 48 269 4.3E-49 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSH58p_13355 64c7c021ed3f545f604a3b1c5761f900 451 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 2 449 4.6E-131 T 14-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 TSH58p_13355 64c7c021ed3f545f604a3b1c5761f900 451 SUPERFAMILY SSF102114 6 440 1.7E-120 T 14-10-2018 TSH58p_32140 56f68eaaf584108f1b6f796cc1895f9a 300 PRINTS PR00146 Dihydrodipicolinate synthase signature 72 90 2.7E-17 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_32140 56f68eaaf584108f1b6f796cc1895f9a 300 PRINTS PR00146 Dihydrodipicolinate synthase signature 129 146 2.7E-17 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_32140 56f68eaaf584108f1b6f796cc1895f9a 300 PRINTS PR00146 Dihydrodipicolinate synthase signature 36 57 2.7E-17 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_32140 56f68eaaf584108f1b6f796cc1895f9a 300 PRINTS PR00146 Dihydrodipicolinate synthase signature 104 120 2.7E-17 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_32140 56f68eaaf584108f1b6f796cc1895f9a 300 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 134 164 - T 14-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 TSH58p_32140 56f68eaaf584108f1b6f796cc1895f9a 300 Pfam PF00701 Dihydrodipicolinate synthetase family 5 274 8.4E-55 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_32140 56f68eaaf584108f1b6f796cc1895f9a 300 PIRSF PIRSF001365 1 299 2.1E-72 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_32140 56f68eaaf584108f1b6f796cc1895f9a 300 SUPERFAMILY SSF51569 2 285 5.13E-74 T 14-10-2018 TSH58p_32140 56f68eaaf584108f1b6f796cc1895f9a 300 Gene3D G3DSA:3.20.20.70 1 292 2.0E-83 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_32140 56f68eaaf584108f1b6f796cc1895f9a 300 SMART SM01130 3 292 1.7E-85 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_10605 ffcd47ee85ec2496a21baae96bcf6a51 202 Gene3D G3DSA:2.30.22.10 131 187 3.3E-22 T 14-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 TSH58p_10605 ffcd47ee85ec2496a21baae96bcf6a51 202 Gene3D G3DSA:3.90.20.20 23 129 1.1E-24 T 14-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 TSH58p_10605 ffcd47ee85ec2496a21baae96bcf6a51 202 PRINTS PR00773 GrpE protein signature 52 68 1.5E-23 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TSH58p_10605 ffcd47ee85ec2496a21baae96bcf6a51 202 PRINTS PR00773 GrpE protein signature 166 185 1.5E-23 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TSH58p_10605 ffcd47ee85ec2496a21baae96bcf6a51 202 PRINTS PR00773 GrpE protein signature 80 95 1.5E-23 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TSH58p_10605 ffcd47ee85ec2496a21baae96bcf6a51 202 PRINTS PR00773 GrpE protein signature 139 154 1.5E-23 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TSH58p_10605 ffcd47ee85ec2496a21baae96bcf6a51 202 ProSitePatterns PS01071 grpE protein signature. 142 185 - T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TSH58p_10605 ffcd47ee85ec2496a21baae96bcf6a51 202 SUPERFAMILY SSF58014 35 131 3.4E-25 T 14-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 TSH58p_10605 ffcd47ee85ec2496a21baae96bcf6a51 202 Pfam PF01025 GrpE 22 187 5.9E-52 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TSH58p_10605 ffcd47ee85ec2496a21baae96bcf6a51 202 Hamap MF_01151 Protein GrpE [grpE]. 2 187 19.482 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TSH58p_10605 ffcd47ee85ec2496a21baae96bcf6a51 202 SUPERFAMILY SSF51064 132 188 8.11E-19 T 14-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 TSH58p_19115 3a72250026500deff0781ceadf1f5da0 202 Gene3D G3DSA:2.40.50.140 133 201 4.3E-8 T 14-10-2018 TSH58p_19115 3a72250026500deff0781ceadf1f5da0 202 PRINTS PR00050 Cold shock protein signature 32 41 8.7E-5 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_19115 3a72250026500deff0781ceadf1f5da0 202 PRINTS PR00050 Cold shock protein signature 11 26 8.7E-5 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_19115 3a72250026500deff0781ceadf1f5da0 202 PRINTS PR00050 Cold shock protein signature 47 65 8.7E-5 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_19115 3a72250026500deff0781ceadf1f5da0 202 Pfam PF00313 'Cold-shock' DNA-binding domain 10 71 7.4E-9 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_19115 3a72250026500deff0781ceadf1f5da0 202 Pfam PF00313 'Cold-shock' DNA-binding domain 136 200 5.4E-6 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_19115 3a72250026500deff0781ceadf1f5da0 202 SUPERFAMILY SSF50249 8 73 7.1E-11 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_19115 3a72250026500deff0781ceadf1f5da0 202 SUPERFAMILY SSF50249 131 201 1.89E-7 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_19115 3a72250026500deff0781ceadf1f5da0 202 Gene3D G3DSA:2.40.50.140 8 77 3.7E-12 T 14-10-2018 TSH58p_19115 3a72250026500deff0781ceadf1f5da0 202 SMART SM00357 136 202 3.1 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 TSH58p_19115 3a72250026500deff0781ceadf1f5da0 202 SMART SM00357 10 74 5.9E-4 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 TSH58p_26040 1fb0da9b7b85b822bd701aac7fc03d0c 304 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 149 298 7.1E-50 T 14-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 TSH58p_26040 1fb0da9b7b85b822bd701aac7fc03d0c 304 Gene3D G3DSA:3.40.50.1370 133 287 8.3E-115 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TSH58p_26040 1fb0da9b7b85b822bd701aac7fc03d0c 304 PRINTS PR00102 Ornithine carbamoyltransferase signature 119 133 2.0E-29 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TSH58p_26040 1fb0da9b7b85b822bd701aac7fc03d0c 304 PRINTS PR00102 Ornithine carbamoyltransferase signature 218 228 2.0E-29 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TSH58p_26040 1fb0da9b7b85b822bd701aac7fc03d0c 304 PRINTS PR00102 Ornithine carbamoyltransferase signature 279 290 2.0E-29 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TSH58p_26040 1fb0da9b7b85b822bd701aac7fc03d0c 304 PRINTS PR00102 Ornithine carbamoyltransferase signature 46 60 2.0E-29 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TSH58p_26040 1fb0da9b7b85b822bd701aac7fc03d0c 304 PRINTS PR00102 Ornithine carbamoyltransferase signature 79 92 2.0E-29 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TSH58p_26040 1fb0da9b7b85b822bd701aac7fc03d0c 304 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 5 300 1.3E-113 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TSH58p_26040 1fb0da9b7b85b822bd701aac7fc03d0c 304 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 48 55 - T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSH58p_26040 1fb0da9b7b85b822bd701aac7fc03d0c 304 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 4 301 75.939 T 14-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 TSH58p_26040 1fb0da9b7b85b822bd701aac7fc03d0c 304 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 48 67 8.2E-27 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSH58p_26040 1fb0da9b7b85b822bd701aac7fc03d0c 304 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 265 288 8.2E-27 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSH58p_26040 1fb0da9b7b85b822bd701aac7fc03d0c 304 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 130 141 8.2E-27 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSH58p_26040 1fb0da9b7b85b822bd701aac7fc03d0c 304 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 253 262 8.2E-27 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSH58p_26040 1fb0da9b7b85b822bd701aac7fc03d0c 304 Gene3D G3DSA:3.40.50.1370 13 296 8.3E-115 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TSH58p_26040 1fb0da9b7b85b822bd701aac7fc03d0c 304 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 5 143 4.8E-50 T 14-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 TSH58p_26040 1fb0da9b7b85b822bd701aac7fc03d0c 304 SUPERFAMILY SSF53671 3 301 7.2E-108 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TSH58p_19520 cd5f1ea0813a0bca2c38c017a049fcfa 251 Hamap MF_00943 Maleate isomerase [maiA]. 6 251 50.603 T 14-10-2018 IPR028615 Maleate isomerase GO:0050076 KEGG: 00650+5.2.1.1|KEGG: 00760+5.2.1.1|MetaCyc: PWY-5033|MetaCyc: PWY-6993|MetaCyc: PWY-7128|MetaCyc: PWY-722 TSH58p_19520 cd5f1ea0813a0bca2c38c017a049fcfa 251 PIRSF PIRSF015736 1 251 1.1E-68 T 14-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase TSH58p_19520 cd5f1ea0813a0bca2c38c017a049fcfa 251 Gene3D G3DSA:3.40.50.12500 5 251 3.6E-87 T 14-10-2018 TSH58p_28915 e9e7b15cd61a473993615d804e1b84a3 137 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 29 114 9.0E-16 T 14-10-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 TSH58p_28915 e9e7b15cd61a473993615d804e1b84a3 137 Gene3D G3DSA:2.170.150.70 7 120 7.2E-16 T 14-10-2018 TSH58p_28915 e9e7b15cd61a473993615d804e1b84a3 137 SUPERFAMILY SSF51316 4 135 5.65E-42 T 14-10-2018 IPR011057 Mss4-like superfamily TSH58p_23650 fed8e6cd73ccd4e9c00058a9da22823f 499 SUPERFAMILY SSF47384 230 332 8.63E-10 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_23650 fed8e6cd73ccd4e9c00058a9da22823f 499 PRINTS PR00344 Bacterial sensor protein C-terminal signature 472 485 1.1E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_23650 fed8e6cd73ccd4e9c00058a9da22823f 499 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 430 1.1E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_23650 fed8e6cd73ccd4e9c00058a9da22823f 499 PRINTS PR00344 Bacterial sensor protein C-terminal signature 448 466 1.1E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_23650 fed8e6cd73ccd4e9c00058a9da22823f 499 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 444 1.1E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_23650 fed8e6cd73ccd4e9c00058a9da22823f 499 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 378 486 4.7E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_23650 fed8e6cd73ccd4e9c00058a9da22823f 499 Pfam PF05227 CHASE3 domain 41 174 3.1E-28 T 14-10-2018 IPR007891 CHASE3 TSH58p_23650 fed8e6cd73ccd4e9c00058a9da22823f 499 Gene3D G3DSA:1.20.1440.210 49 173 9.8E-25 T 14-10-2018 TSH58p_23650 fed8e6cd73ccd4e9c00058a9da22823f 499 SMART SM00387 377 488 1.5E-31 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_23650 fed8e6cd73ccd4e9c00058a9da22823f 499 SUPERFAMILY SSF55874 336 487 2.62E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_23650 fed8e6cd73ccd4e9c00058a9da22823f 499 Gene3D G3DSA:3.30.565.10 332 486 3.2E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_23650 fed8e6cd73ccd4e9c00058a9da22823f 499 Gene3D G3DSA:1.10.287.130 232 331 1.7E-10 T 14-10-2018 TSH58p_23650 fed8e6cd73ccd4e9c00058a9da22823f 499 SMART SM00388 245 335 6.6E-4 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_18325 ecb65fd73fde004966f5194c376632be 1409 SUPERFAMILY SSF53448 381 622 4.99E-36 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_18325 ecb65fd73fde004966f5194c376632be 1409 Gene3D G3DSA:3.90.550.10 392 625 1.2E-31 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_18325 ecb65fd73fde004966f5194c376632be 1409 SUPERFAMILY SSF53756 685 1043 2.43E-25 T 14-10-2018 TSH58p_18325 ecb65fd73fde004966f5194c376632be 1409 Gene3D G3DSA:3.40.50.2000 914 1062 1.8E-9 T 14-10-2018 TSH58p_18325 ecb65fd73fde004966f5194c376632be 1409 Pfam PF13439 Glycosyltransferase Family 4 687 899 5.2E-7 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TSH58p_18325 ecb65fd73fde004966f5194c376632be 1409 Gene3D G3DSA:1.25.40.10 24 149 9.7E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_18325 ecb65fd73fde004966f5194c376632be 1409 Gene3D G3DSA:3.40.50.2000 679 902 9.2E-6 T 14-10-2018 TSH58p_18325 ecb65fd73fde004966f5194c376632be 1409 Pfam PF00535 Glycosyl transferase family 2 399 513 7.6E-13 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_24260 cada271a0f7b2849654817004f9c2025 312 SUPERFAMILY SSF52402 2 184 9.21E-58 T 14-10-2018 TSH58p_24260 cada271a0f7b2849654817004f9c2025 312 SUPERFAMILY SSF52467 187 309 1.16E-49 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TSH58p_24260 cada271a0f7b2849654817004f9c2025 312 Pfam PF01012 Electron transfer flavoprotein domain 4 167 6.8E-41 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 TSH58p_24260 cada271a0f7b2849654817004f9c2025 312 Gene3D G3DSA:3.40.50.620 2 183 3.2E-57 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_24260 cada271a0f7b2849654817004f9c2025 312 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 253 279 - T 14-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 TSH58p_24260 cada271a0f7b2849654817004f9c2025 312 Gene3D G3DSA:3.40.50.1220 184 312 4.4E-60 T 14-10-2018 TSH58p_24260 cada271a0f7b2849654817004f9c2025 312 SMART SM00893 3 182 1.8E-54 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 TSH58p_24260 cada271a0f7b2849654817004f9c2025 312 PIRSF PIRSF000089 1 312 2.9E-110 T 14-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 TSH58p_24260 cada271a0f7b2849654817004f9c2025 312 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 190 272 5.7E-38 T 14-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 TSH58p_21670 a3bdb9ca80f9f44a0a721c8a2190d7f5 608 PIRSF PIRSF002741 1 600 2.7E-107 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TSH58p_21670 a3bdb9ca80f9f44a0a721c8a2190d7f5 608 Gene3D G3DSA:3.10.105.10 316 575 2.2E-261 T 14-10-2018 TSH58p_21670 a3bdb9ca80f9f44a0a721c8a2190d7f5 608 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 106 510 1.0E-80 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain TSH58p_21670 a3bdb9ca80f9f44a0a721c8a2190d7f5 608 Gene3D G3DSA:3.40.190.10 33 595 2.2E-261 T 14-10-2018 TSH58p_21670 a3bdb9ca80f9f44a0a721c8a2190d7f5 608 SUPERFAMILY SSF53850 55 596 3.26E-132 T 14-10-2018 TSH58p_16440 688ef7cc4698b59a038fd6ee735e3bbb 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 288 298 4.4E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_16440 688ef7cc4698b59a038fd6ee735e3bbb 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 270 284 4.4E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_16440 688ef7cc4698b59a038fd6ee735e3bbb 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 326 339 4.4E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_16440 688ef7cc4698b59a038fd6ee735e3bbb 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 301 319 4.4E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_16440 688ef7cc4698b59a038fd6ee735e3bbb 349 SMART SM00387 224 342 1.7E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_16440 688ef7cc4698b59a038fd6ee735e3bbb 349 Gene3D G3DSA:1.10.287.130 74 174 1.8E-19 T 14-10-2018 TSH58p_16440 688ef7cc4698b59a038fd6ee735e3bbb 349 SUPERFAMILY SSF55874 181 340 4.32E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_16440 688ef7cc4698b59a038fd6ee735e3bbb 349 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 227 340 7.0E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_16440 688ef7cc4698b59a038fd6ee735e3bbb 349 Gene3D G3DSA:3.30.565.10 175 340 1.8E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_07530 8d5d9068c76c2323d848681c33d66dd8 323 Pfam PF13533 Biotin-lipoyl like 36 89 3.9E-6 T 14-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain TSH58p_07530 8d5d9068c76c2323d848681c33d66dd8 323 Gene3D G3DSA:2.40.30.170 232 276 3.6E-9 T 14-10-2018 TSH58p_07530 8d5d9068c76c2323d848681c33d66dd8 323 Gene3D G3DSA:2.40.50.100 197 231 3.6E-9 T 14-10-2018 TSH58p_07530 8d5d9068c76c2323d848681c33d66dd8 323 Gene3D G3DSA:1.10.287.470 170 196 3.6E-9 T 14-10-2018 TSH58p_07530 8d5d9068c76c2323d848681c33d66dd8 323 Pfam PF13437 HlyD family secretion protein 199 305 8.8E-12 T 14-10-2018 TSH58p_07530 8d5d9068c76c2323d848681c33d66dd8 323 Gene3D G3DSA:2.40.50.100 35 101 1.8E-8 T 14-10-2018 TSH58p_07530 8d5d9068c76c2323d848681c33d66dd8 323 SUPERFAMILY SSF111369 34 89 3.79E-7 T 14-10-2018 TSH58p_07530 8d5d9068c76c2323d848681c33d66dd8 323 Gene3D G3DSA:1.10.287.470 102 164 6.7E-6 T 14-10-2018 TSH58p_30525 518790af04aa06e637eb5dafa198e343 334 Pfam PF00676 Dehydrogenase E1 component 24 317 8.1E-60 T 14-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 TSH58p_30525 518790af04aa06e637eb5dafa198e343 334 Gene3D G3DSA:3.40.50.970 3 333 3.1E-109 T 14-10-2018 TSH58p_30525 518790af04aa06e637eb5dafa198e343 334 SUPERFAMILY SSF52518 7 327 2.24E-90 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_11295 327e0f12c28b305dfa4c85059bcde134 184 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 119 183 4.0E-27 T 14-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 TSH58p_11295 327e0f12c28b305dfa4c85059bcde134 184 SUPERFAMILY SSF117916 104 183 5.23E-29 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TSH58p_11295 327e0f12c28b305dfa4c85059bcde134 184 SMART SM00932 3 89 5.5E-49 T 14-10-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal TSH58p_11295 327e0f12c28b305dfa4c85059bcde134 184 SUPERFAMILY SSF110836 1 90 2.48E-30 T 14-10-2018 IPR036498 Scaffold protein Nfu/NifU, N-terminal domain superfamily TSH58p_11295 327e0f12c28b305dfa4c85059bcde134 184 Pfam PF01106 NifU-like domain 115 180 1.3E-30 T 14-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 TSH58p_11295 327e0f12c28b305dfa4c85059bcde134 184 Gene3D G3DSA:3.30.300.130 109 183 3.2E-33 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TSH58p_11295 327e0f12c28b305dfa4c85059bcde134 184 Pfam PF08712 Scaffold protein Nfu/NifU N terminal 3 88 1.4E-31 T 14-10-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal TSH58p_11295 327e0f12c28b305dfa4c85059bcde134 184 Gene3D G3DSA:3.30.1370.70 1 96 7.0E-35 T 14-10-2018 IPR036498 Scaffold protein Nfu/NifU, N-terminal domain superfamily TSH58p_11295 327e0f12c28b305dfa4c85059bcde134 184 PIRSF PIRSF036773 1 184 8.1E-79 T 14-10-2018 IPR035433 NFU1-like TSH58p_13260 b318772f3805965bd53a5dcd1a7a72f9 404 Pfam PF00155 Aminotransferase class I and II 47 391 4.8E-80 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSH58p_13260 b318772f3805965bd53a5dcd1a7a72f9 404 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 245 254 - T 14-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 TSH58p_13260 b318772f3805965bd53a5dcd1a7a72f9 404 TIGRFAM TIGR01821 5aminolev_synth: 5-aminolevulinic acid synthase 1 402 4.4E-204 T 14-10-2018 IPR010961 Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase GO:0003870|GO:0030170|GO:0033014 KEGG: 00260+2.3.1.37|KEGG: 00860+2.3.1.37|MetaCyc: PWY-5189|MetaCyc: PWY-7536|Reactome: R-HSA-189451 TSH58p_13260 b318772f3805965bd53a5dcd1a7a72f9 404 Gene3D G3DSA:3.90.1150.10 14 388 5.5E-169 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_13260 b318772f3805965bd53a5dcd1a7a72f9 404 SUPERFAMILY SSF53383 3 399 4.98E-113 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_13260 b318772f3805965bd53a5dcd1a7a72f9 404 Gene3D G3DSA:3.40.640.10 63 298 5.5E-169 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_06920 2c00cd3f5a7b64caa14be23b3839bbda 155 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 1 149 4.2E-60 T 14-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TSH58p_06920 2c00cd3f5a7b64caa14be23b3839bbda 155 SUPERFAMILY SSF52255 1 151 3.14E-61 T 14-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 TSH58p_06920 2c00cd3f5a7b64caa14be23b3839bbda 155 PIRSF PIRSF001338 1 153 3.8E-61 T 14-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 TSH58p_06920 2c00cd3f5a7b64caa14be23b3839bbda 155 Gene3D G3DSA:3.40.50.7700 1 154 3.3E-66 T 14-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 TSH58p_06920 2c00cd3f5a7b64caa14be23b3839bbda 155 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 1 150 29.124 T 14-10-2018 IPR033747 Class I PurE TSH58p_06920 2c00cd3f5a7b64caa14be23b3839bbda 155 SMART SM01001 1 146 1.7E-91 T 14-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TSH58p_06920 2c00cd3f5a7b64caa14be23b3839bbda 155 Pfam PF00731 AIR carboxylase 1 143 3.9E-59 T 14-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TSH58p_08235 1429deb87e0ad38d0845a2a46fa8037a 644 SUPERFAMILY SSF52540 333 574 3.97E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_08235 1429deb87e0ad38d0845a2a46fa8037a 644 Gene3D G3DSA:1.10.10.60 601 638 8.2E-8 T 14-10-2018 TSH58p_08235 1429deb87e0ad38d0845a2a46fa8037a 644 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 544 553 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site TSH58p_08235 1429deb87e0ad38d0845a2a46fa8037a 644 SMART SM00382 352 496 1.6E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_08235 1429deb87e0ad38d0845a2a46fa8037a 644 Pfam PF00158 Sigma-54 interaction domain 333 496 1.7E-64 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 TSH58p_08235 1429deb87e0ad38d0845a2a46fa8037a 644 Gene3D G3DSA:3.40.50.300 322 504 3.4E-59 T 14-10-2018 TSH58p_08235 1429deb87e0ad38d0845a2a46fa8037a 644 SUPERFAMILY SSF46689 599 637 3.85E-6 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_08235 1429deb87e0ad38d0845a2a46fa8037a 644 SUPERFAMILY SSF55785 229 301 7.68E-7 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_08235 1429deb87e0ad38d0845a2a46fa8037a 644 SUPERFAMILY SSF55781 63 203 2.31E-5 T 14-10-2018 TSH58p_08235 1429deb87e0ad38d0845a2a46fa8037a 644 Gene3D G3DSA:3.30.450.20 223 306 6.1E-6 T 14-10-2018 TSH58p_08235 1429deb87e0ad38d0845a2a46fa8037a 644 Pfam PF01590 GAF domain 80 204 1.3E-6 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_08235 1429deb87e0ad38d0845a2a46fa8037a 644 Gene3D G3DSA:1.10.8.60 505 579 2.1E-12 T 14-10-2018 TSH58p_08235 1429deb87e0ad38d0845a2a46fa8037a 644 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 601 618 6.5E-5 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_08235 1429deb87e0ad38d0845a2a46fa8037a 644 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 618 638 6.5E-5 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_08235 1429deb87e0ad38d0845a2a46fa8037a 644 Gene3D G3DSA:3.30.450.40 17 207 6.5E-41 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_08235 1429deb87e0ad38d0845a2a46fa8037a 644 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 356 369 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 TSH58p_08235 1429deb87e0ad38d0845a2a46fa8037a 644 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 419 434 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 TSH58p_08235 1429deb87e0ad38d0845a2a46fa8037a 644 Pfam PF02954 Bacterial regulatory protein, Fis family 603 635 4.3E-5 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_28540 8550e6ccbe06f4420b5cfd4cfae2c2f8 961 Gene3D G3DSA:3.40.50.2300 708 831 6.8E-35 T 14-10-2018 TSH58p_28540 8550e6ccbe06f4420b5cfd4cfae2c2f8 961 SUPERFAMILY SSF47384 442 523 1.06E-15 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_28540 8550e6ccbe06f4420b5cfd4cfae2c2f8 961 Gene3D G3DSA:1.20.120.160 857 956 1.3E-8 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_28540 8550e6ccbe06f4420b5cfd4cfae2c2f8 961 PRINTS PR00344 Bacterial sensor protein C-terminal signature 632 642 1.2E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_28540 8550e6ccbe06f4420b5cfd4cfae2c2f8 961 PRINTS PR00344 Bacterial sensor protein C-terminal signature 651 669 1.2E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_28540 8550e6ccbe06f4420b5cfd4cfae2c2f8 961 PRINTS PR00344 Bacterial sensor protein C-terminal signature 675 688 1.2E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_28540 8550e6ccbe06f4420b5cfd4cfae2c2f8 961 PRINTS PR00344 Bacterial sensor protein C-terminal signature 614 628 1.2E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_28540 8550e6ccbe06f4420b5cfd4cfae2c2f8 961 SUPERFAMILY SSF52172 710 830 3.42E-35 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_28540 8550e6ccbe06f4420b5cfd4cfae2c2f8 961 Pfam PF07695 7TM diverse intracellular signalling 225 417 1.1E-8 T 14-10-2018 IPR011623 7TM-DISM receptor, extracellular domain, type 1 TSH58p_28540 8550e6ccbe06f4420b5cfd4cfae2c2f8 961 Gene3D G3DSA:1.10.287.130 421 520 4.6E-17 T 14-10-2018 TSH58p_28540 8550e6ccbe06f4420b5cfd4cfae2c2f8 961 Gene3D G3DSA:3.30.565.10 521 691 1.2E-41 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_28540 8550e6ccbe06f4420b5cfd4cfae2c2f8 961 Pfam PF01627 Hpt domain 867 952 2.4E-8 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TSH58p_28540 8550e6ccbe06f4420b5cfd4cfae2c2f8 961 Pfam PF00072 Response regulator receiver domain 713 826 3.1E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_28540 8550e6ccbe06f4420b5cfd4cfae2c2f8 961 SUPERFAMILY SSF49785 58 207 1.68E-8 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily TSH58p_28540 8550e6ccbe06f4420b5cfd4cfae2c2f8 961 SMART SM00448 711 826 4.0E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_28540 8550e6ccbe06f4420b5cfd4cfae2c2f8 961 SMART SM00387 569 691 8.7E-31 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_28540 8550e6ccbe06f4420b5cfd4cfae2c2f8 961 SMART SM00388 457 522 1.7E-17 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_28540 8550e6ccbe06f4420b5cfd4cfae2c2f8 961 Gene3D G3DSA:2.60.120.260 59 208 7.4E-7 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily TSH58p_28540 8550e6ccbe06f4420b5cfd4cfae2c2f8 961 SUPERFAMILY SSF47226 860 950 6.54E-11 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_28540 8550e6ccbe06f4420b5cfd4cfae2c2f8 961 SUPERFAMILY SSF55874 512 693 1.7E-43 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_28540 8550e6ccbe06f4420b5cfd4cfae2c2f8 961 Pfam PF00512 His Kinase A (phospho-acceptor) domain 458 522 1.4E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_28540 8550e6ccbe06f4420b5cfd4cfae2c2f8 961 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 570 689 2.8E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_27265 5276b3ff5655b25d83d693f612179bca 861 Pfam PF06434 Aconitate hydratase 2 N-terminus 168 380 4.3E-94 T 14-10-2018 IPR015929 Aconitase B, swivel GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 TSH58p_27265 5276b3ff5655b25d83d693f612179bca 861 Gene3D G3DSA:3.20.19.10 162 359 2.5E-69 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 TSH58p_27265 5276b3ff5655b25d83d693f612179bca 861 SUPERFAMILY SSF74778 2 160 2.88E-64 T 14-10-2018 IPR036288 Aconitase B, HEAT-like domain superfamily GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 TSH58p_27265 5276b3ff5655b25d83d693f612179bca 861 Gene3D G3DSA:3.30.499.10 684 861 1.9E-64 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 TSH58p_27265 5276b3ff5655b25d83d693f612179bca 861 SUPERFAMILY SSF52016 162 370 1.02E-64 T 14-10-2018 TSH58p_27265 5276b3ff5655b25d83d693f612179bca 861 PIRSF PIRSF036687 1 859 0.0 T 14-10-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 TSH58p_27265 5276b3ff5655b25d83d693f612179bca 861 Gene3D G3DSA:3.30.499.10 403 530 9.3E-149 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 TSH58p_27265 5276b3ff5655b25d83d693f612179bca 861 SUPERFAMILY SSF53732 377 854 9.68E-145 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 TSH58p_27265 5276b3ff5655b25d83d693f612179bca 861 Gene3D G3DSA:3.40.1060.10 383 682 9.3E-149 T 14-10-2018 IPR015932 Aconitase, domain 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-1268020|Reactome: R-HSA-71403 TSH58p_27265 5276b3ff5655b25d83d693f612179bca 861 Pfam PF00330 Aconitase family (aconitate hydratase) 472 818 4.2E-38 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_27265 5276b3ff5655b25d83d693f612179bca 861 Pfam PF11791 Aconitate B N-terminal domain 4 156 8.3E-62 T 14-10-2018 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 TSH58p_27265 5276b3ff5655b25d83d693f612179bca 861 Gene3D G3DSA:1.25.40.310 1 161 1.0E-64 T 14-10-2018 IPR036288 Aconitase B, HEAT-like domain superfamily GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 TSH58p_27265 5276b3ff5655b25d83d693f612179bca 861 ProSitePatterns PS00450 Aconitase family signature 1. 703 720 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 TSH58p_27265 5276b3ff5655b25d83d693f612179bca 861 TIGRFAM TIGR00117 acnB: aconitate hydratase 2 1 854 0.0 T 14-10-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 TSH58p_19765 df1f49a5c1d94c78b14c29dde972367c 293 SUPERFAMILY SSF57884 218 290 4.97E-30 T 14-10-2018 IPR035451 Ada-like domain superfamily TSH58p_19765 df1f49a5c1d94c78b14c29dde972367c 293 Gene3D G3DSA:3.40.10.10 215 287 6.2E-31 T 14-10-2018 IPR035451 Ada-like domain superfamily TSH58p_19765 df1f49a5c1d94c78b14c29dde972367c 293 Pfam PF02805 Metal binding domain of Ada 225 286 6.6E-30 T 14-10-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 TSH58p_04885 3568313a23c612c4a5cc9714bb3bdbbf 436 Gene3D G3DSA:2.160.20.80 258 365 3.5E-24 T 14-10-2018 TSH58p_04885 3568313a23c612c4a5cc9714bb3bdbbf 436 Gene3D G3DSA:2.160.20.100 366 429 1.2E-17 T 14-10-2018 TSH58p_04885 3568313a23c612c4a5cc9714bb3bdbbf 436 Gene3D G3DSA:2.160.20.80 9 116 1.1E-24 T 14-10-2018 TSH58p_04885 3568313a23c612c4a5cc9714bb3bdbbf 436 SUPERFAMILY SSF141571 25 113 3.01E-23 T 14-10-2018 TSH58p_04885 3568313a23c612c4a5cc9714bb3bdbbf 436 SUPERFAMILY SSF141571 125 244 2.09E-32 T 14-10-2018 TSH58p_04885 3568313a23c612c4a5cc9714bb3bdbbf 436 SUPERFAMILY SSF141571 268 428 3.06E-36 T 14-10-2018 TSH58p_04885 3568313a23c612c4a5cc9714bb3bdbbf 436 Pfam PF00805 Pentapeptide repeats (8 copies) 275 309 3.7E-10 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_04885 3568313a23c612c4a5cc9714bb3bdbbf 436 Pfam PF00805 Pentapeptide repeats (8 copies) 191 230 2.2E-14 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_04885 3568313a23c612c4a5cc9714bb3bdbbf 436 Pfam PF00805 Pentapeptide repeats (8 copies) 48 83 2.1E-10 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_04885 3568313a23c612c4a5cc9714bb3bdbbf 436 Pfam PF00805 Pentapeptide repeats (8 copies) 391 428 2.9E-11 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_04885 3568313a23c612c4a5cc9714bb3bdbbf 436 Pfam PF00805 Pentapeptide repeats (8 copies) 315 350 2.0E-9 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_04885 3568313a23c612c4a5cc9714bb3bdbbf 436 Pfam PF00805 Pentapeptide repeats (8 copies) 127 160 3.3E-7 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_04885 3568313a23c612c4a5cc9714bb3bdbbf 436 Gene3D G3DSA:2.160.20.80 118 257 2.1E-33 T 14-10-2018 TSH58p_31115 176414d80eb84b15b3df09e7564c8678 469 Pfam PF03972 MmgE/PrpD family 18 444 7.6E-93 T 14-10-2018 IPR005656 MmgE/PrpD GO:0016829 TSH58p_31115 176414d80eb84b15b3df09e7564c8678 469 Gene3D G3DSA:1.10.4100.10 39 430 6.4E-104 T 14-10-2018 TSH58p_31115 176414d80eb84b15b3df09e7564c8678 469 Gene3D G3DSA:3.30.1330.120 277 412 6.4E-104 T 14-10-2018 TSH58p_31115 176414d80eb84b15b3df09e7564c8678 469 SUPERFAMILY SSF103378 14 457 8.24E-96 T 14-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 TSH58p_27760 475c49655ecb22a2dcd40f44a5075478 230 Gene3D G3DSA:1.10.10.10 3 70 1.6E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_27760 475c49655ecb22a2dcd40f44a5075478 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 64 1.1E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_27760 475c49655ecb22a2dcd40f44a5075478 230 SMART SM00895 92 213 1.9E-15 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_27760 475c49655ecb22a2dcd40f44a5075478 230 SUPERFAMILY SSF48008 89 217 1.49E-21 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_27760 475c49655ecb22a2dcd40f44a5075478 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 3.9E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_27760 475c49655ecb22a2dcd40f44a5075478 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 3.9E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_27760 475c49655ecb22a2dcd40f44a5075478 230 Gene3D G3DSA:1.20.120.530 87 223 5.9E-24 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_27760 475c49655ecb22a2dcd40f44a5075478 230 SMART SM00345 10 67 7.8E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_27760 475c49655ecb22a2dcd40f44a5075478 230 SUPERFAMILY SSF46785 3 71 2.88E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_27760 475c49655ecb22a2dcd40f44a5075478 230 Pfam PF07729 FCD domain 92 212 1.8E-22 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_06065 474c949b5bed67817116246617132a19 912 Gene3D G3DSA:3.30.450.350 77 280 1.4E-14 T 14-10-2018 TSH58p_06065 474c949b5bed67817116246617132a19 912 SMART SM00267 457 629 1.0E-67 T 14-10-2018 IPR000160 GGDEF domain TSH58p_06065 474c949b5bed67817116246617132a19 912 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 343 462 5.6E-11 T 14-10-2018 IPR000014 PAS domain TSH58p_06065 474c949b5bed67817116246617132a19 912 SMART SM00052 639 885 5.8E-114 T 14-10-2018 IPR001633 EAL domain TSH58p_06065 474c949b5bed67817116246617132a19 912 SUPERFAMILY SSF55785 339 454 1.08E-14 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_06065 474c949b5bed67817116246617132a19 912 Gene3D G3DSA:3.30.450.20 334 464 4.1E-17 T 14-10-2018 TSH58p_06065 474c949b5bed67817116246617132a19 912 Pfam PF00990 Diguanylate cyclase, GGDEF domain 468 624 4.4E-51 T 14-10-2018 IPR000160 GGDEF domain TSH58p_06065 474c949b5bed67817116246617132a19 912 Pfam PF08448 PAS fold 353 459 4.0E-10 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_06065 474c949b5bed67817116246617132a19 912 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 467 627 1.5E-42 T 14-10-2018 IPR000160 GGDEF domain TSH58p_06065 474c949b5bed67817116246617132a19 912 SUPERFAMILY SSF55073 473 630 1.02E-51 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_06065 474c949b5bed67817116246617132a19 912 SUPERFAMILY SSF141868 645 890 1.31E-89 T 14-10-2018 IPR035919 EAL domain superfamily TSH58p_06065 474c949b5bed67817116246617132a19 912 Pfam PF03924 CHASE domain 76 239 3.4E-32 T 14-10-2018 IPR006189 CHASE domain TSH58p_06065 474c949b5bed67817116246617132a19 912 Pfam PF00563 EAL domain 645 880 1.0E-76 T 14-10-2018 IPR001633 EAL domain TSH58p_06065 474c949b5bed67817116246617132a19 912 Gene3D G3DSA:3.30.70.270 465 641 2.8E-61 T 14-10-2018 TSH58p_06065 474c949b5bed67817116246617132a19 912 Gene3D G3DSA:3.20.20.450 642 892 4.0E-101 T 14-10-2018 IPR035919 EAL domain superfamily TSH58p_06065 474c949b5bed67817116246617132a19 912 SMART SM01079 73 261 4.2E-34 T 14-10-2018 IPR006189 CHASE domain TSH58p_24200 714116b9d96c9c02f81ae1c4241852df 601 SMART SM00028 4 37 98.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24200 714116b9d96c9c02f81ae1c4241852df 601 SMART SM00028 72 105 17.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24200 714116b9d96c9c02f81ae1c4241852df 601 SMART SM00028 38 71 93.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24200 714116b9d96c9c02f81ae1c4241852df 601 SUPERFAMILY SSF48452 4 127 5.2E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_24200 714116b9d96c9c02f81ae1c4241852df 601 Pfam PF13432 Tetratricopeptide repeat 9 72 2.3E-8 T 14-10-2018 TSH58p_24200 714116b9d96c9c02f81ae1c4241852df 601 SUPERFAMILY SSF53756 314 593 3.95E-18 T 14-10-2018 TSH58p_24200 714116b9d96c9c02f81ae1c4241852df 601 Gene3D G3DSA:1.25.40.10 5 135 1.3E-20 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_24200 714116b9d96c9c02f81ae1c4241852df 601 Pfam PF13692 Glycosyl transferases group 1 433 563 2.8E-9 T 14-10-2018 TSH58p_24200 714116b9d96c9c02f81ae1c4241852df 601 Gene3D G3DSA:3.40.50.2000 416 582 1.6E-15 T 14-10-2018 TSH58p_31940 0cbd0bd63ef37143a578ccc28f2957b7 300 SUPERFAMILY SSF53850 91 296 6.86E-40 T 14-10-2018 TSH58p_31940 0cbd0bd63ef37143a578ccc28f2957b7 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 64 1.2E-15 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_31940 0cbd0bd63ef37143a578ccc28f2957b7 300 Gene3D G3DSA:1.10.10.10 4 92 7.6E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_31940 0cbd0bd63ef37143a578ccc28f2957b7 300 SUPERFAMILY SSF46785 4 111 4.01E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_31940 0cbd0bd63ef37143a578ccc28f2957b7 300 Pfam PF03466 LysR substrate binding domain 90 296 2.9E-34 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_31940 0cbd0bd63ef37143a578ccc28f2957b7 300 Gene3D G3DSA:3.40.190.290 93 297 1.5E-33 T 14-10-2018 TSH58p_11965 c3286608adf31a64f2dc70cda3fd0009 423 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 107 115 - T 14-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 TSH58p_11965 c3286608adf31a64f2dc70cda3fd0009 423 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 11 418 52.263 T 14-10-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 TSH58p_11965 c3286608adf31a64f2dc70cda3fd0009 423 Gene3D G3DSA:3.90.550.10 5 295 5.8E-90 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_11965 c3286608adf31a64f2dc70cda3fd0009 423 SUPERFAMILY SSF51161 305 409 2.72E-16 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily TSH58p_11965 c3286608adf31a64f2dc70cda3fd0009 423 Pfam PF00483 Nucleotidyl transferase 16 285 2.3E-67 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TSH58p_11965 c3286608adf31a64f2dc70cda3fd0009 423 Gene3D G3DSA:2.160.10.10 296 423 2.3E-36 T 14-10-2018 TSH58p_11965 c3286608adf31a64f2dc70cda3fd0009 423 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 205 215 - T 14-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 TSH58p_11965 c3286608adf31a64f2dc70cda3fd0009 423 SUPERFAMILY SSF53448 14 385 8.68E-77 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_11965 c3286608adf31a64f2dc70cda3fd0009 423 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 15 392 6.2E-156 T 14-10-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 TSH58p_02340 921733c3ff0a80d3f37217079191414d 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 205 1.5E-22 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_02340 921733c3ff0a80d3f37217079191414d 215 SUPERFAMILY SSF52172 1 126 6.83E-33 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_02340 921733c3ff0a80d3f37217079191414d 215 SMART SM00421 148 205 1.3E-22 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_02340 921733c3ff0a80d3f37217079191414d 215 Gene3D G3DSA:1.10.10.10 143 209 4.6E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_02340 921733c3ff0a80d3f37217079191414d 215 ProSitePatterns PS00622 LuxR-type HTH domain signature. 165 192 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_02340 921733c3ff0a80d3f37217079191414d 215 Gene3D G3DSA:3.40.50.2300 1 122 4.0E-45 T 14-10-2018 TSH58p_02340 921733c3ff0a80d3f37217079191414d 215 SMART SM00448 1 112 1.5E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_02340 921733c3ff0a80d3f37217079191414d 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 1.9E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_02340 921733c3ff0a80d3f37217079191414d 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 1.9E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_02340 921733c3ff0a80d3f37217079191414d 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 1.9E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_02340 921733c3ff0a80d3f37217079191414d 215 Pfam PF00072 Response regulator receiver domain 3 112 1.1E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_02340 921733c3ff0a80d3f37217079191414d 215 SUPERFAMILY SSF46894 140 211 3.23E-21 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_00400 f208de03ce301eb0b20e7930f5cd34e8 296 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 162 3.7E-50 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 TSH58p_00400 f208de03ce301eb0b20e7930f5cd34e8 296 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 292 5.7E-40 T 14-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 TSH58p_00400 f208de03ce301eb0b20e7930f5cd34e8 296 PIRSF PIRSF000103 1 296 7.3E-85 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 TSH58p_00400 f208de03ce301eb0b20e7930f5cd34e8 296 SUPERFAMILY SSF48179 163 294 1.7E-42 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_00400 f208de03ce301eb0b20e7930f5cd34e8 296 Gene3D G3DSA:3.40.50.720 1 163 4.7E-56 T 14-10-2018 TSH58p_00400 f208de03ce301eb0b20e7930f5cd34e8 296 Gene3D G3DSA:1.10.1040.10 165 296 1.9E-47 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSH58p_00400 f208de03ce301eb0b20e7930f5cd34e8 296 SUPERFAMILY SSF51735 3 162 2.69E-44 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_00400 f208de03ce301eb0b20e7930f5cd34e8 296 TIGRFAM TIGR01692 HIBADH: 3-hydroxyisobutyrate dehydrogenase 6 293 4.5E-131 T 14-10-2018 IPR011548 3-hydroxyisobutyrate dehydrogenase GO:0008442|GO:0051287|GO:0055114 KEGG: 00280+1.1.1.31|Reactome: R-HSA-70895 TSH58p_18095 e4b3331a17f3794ec522e1d4844655c7 192 ProSitePatterns PS00893 Nudix box signature. 81 102 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TSH58p_18095 e4b3331a17f3794ec522e1d4844655c7 192 Gene3D G3DSA:3.90.79.10 5 191 6.8E-38 T 14-10-2018 TSH58p_18095 e4b3331a17f3794ec522e1d4844655c7 192 SUPERFAMILY SSF55811 13 173 4.33E-32 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TSH58p_18095 e4b3331a17f3794ec522e1d4844655c7 192 Pfam PF00293 NUDIX domain 49 157 3.0E-13 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TSH58p_11130 01444f4458baa89880dfaa987422d547 261 SUPERFAMILY SSF51366 1 251 1.73E-87 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TSH58p_11130 01444f4458baa89880dfaa987422d547 261 Pfam PF00977 Histidine biosynthesis protein 5 235 2.2E-93 T 14-10-2018 IPR006062 Histidine biosynthesis GO:0000105 TSH58p_11130 01444f4458baa89880dfaa987422d547 261 Gene3D G3DSA:3.20.20.70 1 259 6.0E-111 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_11130 01444f4458baa89880dfaa987422d547 261 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 251 3.2E-111 T 14-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 TSH58p_11130 01444f4458baa89880dfaa987422d547 261 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 251 48.851 T 14-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 TSH58p_22845 336c0511fb02d97d883645189bdfd71e 831 SMART SM00448 706 814 1.9E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_22845 336c0511fb02d97d883645189bdfd71e 831 Pfam PF07536 HWE histidine kinase 497 574 3.9E-21 T 14-10-2018 IPR011102 Signal transduction histidine kinase, HWE region GO:0004673 TSH58p_22845 336c0511fb02d97d883645189bdfd71e 831 Gene3D G3DSA:3.30.450.20 243 352 3.1E-21 T 14-10-2018 TSH58p_22845 336c0511fb02d97d883645189bdfd71e 831 Gene3D G3DSA:3.30.450.20 355 489 6.0E-15 T 14-10-2018 TSH58p_22845 336c0511fb02d97d883645189bdfd71e 831 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 365 491 5.5E-14 T 14-10-2018 IPR000014 PAS domain TSH58p_22845 336c0511fb02d97d883645189bdfd71e 831 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 243 363 4.9E-14 T 14-10-2018 IPR000014 PAS domain TSH58p_22845 336c0511fb02d97d883645189bdfd71e 831 SMART SM00086 442 484 2.2 T 14-10-2018 IPR001610 PAC motif TSH58p_22845 336c0511fb02d97d883645189bdfd71e 831 SMART SM00086 192 234 5.1 T 14-10-2018 IPR001610 PAC motif TSH58p_22845 336c0511fb02d97d883645189bdfd71e 831 SMART SM00086 318 356 2.4 T 14-10-2018 IPR001610 PAC motif TSH58p_22845 336c0511fb02d97d883645189bdfd71e 831 SUPERFAMILY SSF52172 705 818 8.97E-21 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_22845 336c0511fb02d97d883645189bdfd71e 831 SMART SM00911 497 575 6.5E-27 T 14-10-2018 IPR011102 Signal transduction histidine kinase, HWE region GO:0004673 TSH58p_22845 336c0511fb02d97d883645189bdfd71e 831 Pfam PF13426 PAS domain 194 233 0.016 T 14-10-2018 IPR000014 PAS domain TSH58p_22845 336c0511fb02d97d883645189bdfd71e 831 Pfam PF13188 PAS domain 368 423 2.0E-4 T 14-10-2018 IPR000014 PAS domain TSH58p_22845 336c0511fb02d97d883645189bdfd71e 831 SUPERFAMILY SSF55785 235 353 3.06E-20 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_22845 336c0511fb02d97d883645189bdfd71e 831 Gene3D G3DSA:3.40.50.2300 705 826 6.0E-37 T 14-10-2018 TSH58p_22845 336c0511fb02d97d883645189bdfd71e 831 SMART SM00091 368 435 2.2E-6 T 14-10-2018 IPR000014 PAS domain TSH58p_22845 336c0511fb02d97d883645189bdfd71e 831 SMART SM00091 246 312 4.2E-9 T 14-10-2018 IPR000014 PAS domain TSH58p_22845 336c0511fb02d97d883645189bdfd71e 831 Gene3D G3DSA:3.30.450.20 99 242 4.8E-11 T 14-10-2018 TSH58p_22845 336c0511fb02d97d883645189bdfd71e 831 Pfam PF00072 Response regulator receiver domain 708 813 3.5E-10 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_22845 336c0511fb02d97d883645189bdfd71e 831 SUPERFAMILY SSF55874 566 676 3.76E-6 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_22845 336c0511fb02d97d883645189bdfd71e 831 SUPERFAMILY SSF55785 100 230 2.62E-8 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_22845 336c0511fb02d97d883645189bdfd71e 831 Pfam PF08447 PAS fold 269 332 1.6E-12 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 TSH58p_22845 336c0511fb02d97d883645189bdfd71e 831 SUPERFAMILY SSF55785 353 482 3.22E-17 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_22845 336c0511fb02d97d883645189bdfd71e 831 Gene3D G3DSA:3.30.565.10 550 677 8.1E-10 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_14155 3fe64425c629728fe296964da2b945b8 145 Gene3D G3DSA:3.10.580.10 1 142 2.1E-34 T 14-10-2018 TSH58p_14155 3fe64425c629728fe296964da2b945b8 145 SMART SM00116 80 127 2.9E-9 T 14-10-2018 IPR000644 CBS domain TSH58p_14155 3fe64425c629728fe296964da2b945b8 145 SMART SM00116 13 62 0.0066 T 14-10-2018 IPR000644 CBS domain TSH58p_14155 3fe64425c629728fe296964da2b945b8 145 SUPERFAMILY SSF54631 3 124 2.91E-28 T 14-10-2018 TSH58p_14155 3fe64425c629728fe296964da2b945b8 145 Pfam PF00571 CBS domain 6 60 1.8E-7 T 14-10-2018 IPR000644 CBS domain TSH58p_14155 3fe64425c629728fe296964da2b945b8 145 Pfam PF00571 CBS domain 74 123 5.8E-14 T 14-10-2018 IPR000644 CBS domain TSH58p_32325 cb38602e2a5bdf14aa26a20a55e095c1 109 Pfam PF01042 Endoribonuclease L-PSP 2 108 3.7E-27 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 TSH58p_32325 cb38602e2a5bdf14aa26a20a55e095c1 109 Gene3D G3DSA:3.30.1330.40 1 109 8.9E-39 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TSH58p_32325 cb38602e2a5bdf14aa26a20a55e095c1 109 SUPERFAMILY SSF55298 2 109 2.67E-31 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TSH58p_32325 cb38602e2a5bdf14aa26a20a55e095c1 109 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 85 103 - T 14-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 TSH58p_24295 f4720bbf0758233b4cdb75a5b41103e3 421 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 7 413 5.8E-147 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSH58p_24295 f4720bbf0758233b4cdb75a5b41103e3 421 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 228 241 - T 14-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site TSH58p_24295 f4720bbf0758233b4cdb75a5b41103e3 421 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 33 371 1.0E-26 T 14-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 TSH58p_24295 f4720bbf0758233b4cdb75a5b41103e3 421 Gene3D G3DSA:2.40.37.10 16 410 6.2E-147 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TSH58p_24295 f4720bbf0758233b4cdb75a5b41103e3 421 Gene3D G3DSA:3.20.20.10 34 275 6.2E-147 T 14-10-2018 IPR029066 PLP-binding barrel TSH58p_24295 f4720bbf0758233b4cdb75a5b41103e3 421 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 77 89 7.6E-22 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TSH58p_24295 f4720bbf0758233b4cdb75a5b41103e3 421 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 190 203 7.6E-22 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TSH58p_24295 f4720bbf0758233b4cdb75a5b41103e3 421 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 270 289 7.6E-22 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TSH58p_24295 f4720bbf0758233b4cdb75a5b41103e3 421 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 371 384 7.6E-22 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TSH58p_24295 f4720bbf0758233b4cdb75a5b41103e3 421 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 57 75 7.6E-22 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TSH58p_24295 f4720bbf0758233b4cdb75a5b41103e3 421 SUPERFAMILY SSF50621 253 417 3.56E-54 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TSH58p_24295 f4720bbf0758233b4cdb75a5b41103e3 421 SUPERFAMILY SSF51419 26 282 3.53E-79 T 14-10-2018 IPR029066 PLP-binding barrel TSH58p_24295 f4720bbf0758233b4cdb75a5b41103e3 421 PRINTS PR01181 Diaminopimelate decarboxylase signature 164 173 7.5E-27 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSH58p_24295 f4720bbf0758233b4cdb75a5b41103e3 421 PRINTS PR01181 Diaminopimelate decarboxylase signature 298 316 7.5E-27 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSH58p_24295 f4720bbf0758233b4cdb75a5b41103e3 421 PRINTS PR01181 Diaminopimelate decarboxylase signature 381 403 7.5E-27 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSH58p_24295 f4720bbf0758233b4cdb75a5b41103e3 421 PRINTS PR01181 Diaminopimelate decarboxylase signature 75 92 7.5E-27 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSH58p_24295 f4720bbf0758233b4cdb75a5b41103e3 421 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 15 414 40.147 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSH58p_24295 f4720bbf0758233b4cdb75a5b41103e3 421 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 36 279 3.8E-59 T 14-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 TSH58p_07740 14a754fc8f90bb8952bd96dc49e096d2 283 SUPERFAMILY SSF52402 1 246 1.14E-73 T 14-10-2018 TSH58p_07740 14a754fc8f90bb8952bd96dc49e096d2 283 Gene3D G3DSA:3.40.50.620 1 264 3.9E-87 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_07740 14a754fc8f90bb8952bd96dc49e096d2 283 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 162 182 - T 14-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 TSH58p_07740 14a754fc8f90bb8952bd96dc49e096d2 283 PIRSF PIRSF000090 1 269 1.1E-93 T 14-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 TSH58p_07740 14a754fc8f90bb8952bd96dc49e096d2 283 SMART SM00893 22 218 1.3E-57 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 TSH58p_07740 14a754fc8f90bb8952bd96dc49e096d2 283 Pfam PF01012 Electron transfer flavoprotein domain 23 190 1.0E-47 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 TSH58p_06530 22904db190fe4cadf32ff5043bb14a5d 330 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 16 293 1.1E-66 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 TSH58p_06530 22904db190fe4cadf32ff5043bb14a5d 330 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 16 303 25.566 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 TSH58p_06530 22904db190fe4cadf32ff5043bb14a5d 330 Gene3D G3DSA:3.40.50.300 20 292 4.6E-79 T 14-10-2018 TSH58p_06530 22904db190fe4cadf32ff5043bb14a5d 330 Pfam PF01715 IPP transferase 49 292 4.5E-60 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 TSH58p_06530 22904db190fe4cadf32ff5043bb14a5d 330 Gene3D G3DSA:1.10.20.140 123 193 4.6E-79 T 14-10-2018 TSH58p_06530 22904db190fe4cadf32ff5043bb14a5d 330 SUPERFAMILY SSF52540 17 161 2.1E-15 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_14575 c4986c6aa3c346b6dfc46ec581f63616 194 SUPERFAMILY SSF50249 121 183 3.92E-10 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_14575 c4986c6aa3c346b6dfc46ec581f63616 194 Pfam PF00313 'Cold-shock' DNA-binding domain 122 183 1.9E-7 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_14575 c4986c6aa3c346b6dfc46ec581f63616 194 Gene3D G3DSA:3.30.160.100 4 114 2.8E-13 T 14-10-2018 IPR036567 Ribosome hibernation promotion factor-like TSH58p_14575 c4986c6aa3c346b6dfc46ec581f63616 194 Gene3D G3DSA:2.40.50.140 121 185 1.3E-9 T 14-10-2018 TSH58p_14575 c4986c6aa3c346b6dfc46ec581f63616 194 SUPERFAMILY SSF69754 4 114 1.57E-17 T 14-10-2018 IPR036567 Ribosome hibernation promotion factor-like TSH58p_14575 c4986c6aa3c346b6dfc46ec581f63616 194 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 6 110 9.4E-15 T 14-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 TSH58p_29920 1cab16f223876ddd5ada5b95c5f933bc 328 PIRSF PIRSF006621 2 326 9.6E-108 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 TSH58p_29920 1cab16f223876ddd5ada5b95c5f933bc 328 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 5 320 1.6E-121 T 14-10-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 TSH58p_29920 1cab16f223876ddd5ada5b95c5f933bc 328 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 96 114 - T 14-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 TSH58p_29920 1cab16f223876ddd5ada5b95c5f933bc 328 Gene3D G3DSA:3.20.20.70 8 249 9.6E-81 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_29920 1cab16f223876ddd5ada5b95c5f933bc 328 Pfam PF01207 Dihydrouridine synthase (Dus) 15 316 9.8E-119 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 TSH58p_29920 1cab16f223876ddd5ada5b95c5f933bc 328 Gene3D G3DSA:1.10.1200.80 254 324 1.3E-9 T 14-10-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 TSH58p_29920 1cab16f223876ddd5ada5b95c5f933bc 328 SUPERFAMILY SSF51395 13 319 5.49E-94 T 14-10-2018 TSH58p_29900 69919ec5858381a777f6d7a8330938e4 155 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 135 6.1E-31 T 14-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 TSH58p_29900 69919ec5858381a777f6d7a8330938e4 155 SUPERFAMILY SSF55961 1 143 2.85E-38 T 14-10-2018 TSH58p_29900 69919ec5858381a777f6d7a8330938e4 155 Gene3D G3DSA:3.30.530.20 2 144 2.9E-48 T 14-10-2018 IPR023393 START-like domain superfamily TSH58p_14935 16009bac31b04d7e90609beaa53b5f59 439 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 40 405 6.3E-171 T 14-10-2018 IPR017777 Urea ABC transporter, substrate-binding protein UrtA-like TSH58p_14935 16009bac31b04d7e90609beaa53b5f59 439 SUPERFAMILY SSF53822 39 410 1.99E-86 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_14935 16009bac31b04d7e90609beaa53b5f59 439 Gene3D G3DSA:3.40.50.2300 155 395 2.0E-130 T 14-10-2018 TSH58p_14935 16009bac31b04d7e90609beaa53b5f59 439 Pfam PF13433 Periplasmic binding protein domain 40 408 2.6E-169 T 14-10-2018 TSH58p_14935 16009bac31b04d7e90609beaa53b5f59 439 Gene3D G3DSA:3.40.50.2300 42 376 2.0E-130 T 14-10-2018 TSH58p_04060 a684240909d2c3847622bced94fa6c11 79 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 41 76 2.0E-13 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 TSH58p_04060 a684240909d2c3847622bced94fa6c11 79 SUPERFAMILY SSF47336 2 75 1.31E-22 T 14-10-2018 IPR036736 ACP-like superfamily TSH58p_04060 a684240909d2c3847622bced94fa6c11 79 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.422 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 TSH58p_04060 a684240909d2c3847622bced94fa6c11 79 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site TSH58p_04060 a684240909d2c3847622bced94fa6c11 79 Gene3D G3DSA:1.10.1200.10 1 79 2.9E-29 T 14-10-2018 IPR036736 ACP-like superfamily TSH58p_04060 a684240909d2c3847622bced94fa6c11 79 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 76 5.9E-33 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 TSH58p_04060 a684240909d2c3847622bced94fa6c11 79 Pfam PF00550 Phosphopantetheine attachment site 6 73 3.9E-13 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain TSH58p_26505 e5551b3bcda197137633c073519d4885 241 Gene3D G3DSA:3.90.470.20 11 152 1.5E-22 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TSH58p_26505 e5551b3bcda197137633c073519d4885 241 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 113 183 9.2E-16 T 14-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TSH58p_26505 e5551b3bcda197137633c073519d4885 241 SUPERFAMILY SSF56214 112 235 1.57E-24 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TSH58p_26505 e5551b3bcda197137633c073519d4885 241 SUPERFAMILY SSF56214 18 98 1.44E-15 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TSH58p_19405 ddad6d3f92165809b2a7c5d29f59b271 161 Gene3D G3DSA:1.10.10.10 11 153 5.3E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_19405 ddad6d3f92165809b2a7c5d29f59b271 161 SUPERFAMILY SSF46785 14 151 1.71E-31 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_19405 ddad6d3f92165809b2a7c5d29f59b271 161 Pfam PF01047 MarR family 43 99 8.1E-14 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_19405 ddad6d3f92165809b2a7c5d29f59b271 161 ProSitePatterns PS01117 MarR-type HTH domain signature. 76 109 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site TSH58p_19405 ddad6d3f92165809b2a7c5d29f59b271 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 60 76 2.4E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_19405 ddad6d3f92165809b2a7c5d29f59b271 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 96 112 2.4E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_19405 ddad6d3f92165809b2a7c5d29f59b271 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 92 2.4E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_19405 ddad6d3f92165809b2a7c5d29f59b271 161 SMART SM00347 36 136 4.1E-23 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_05525 2b32c109fb9595e981d590bc1a943ac1 430 SUPERFAMILY SSF52402 7 191 1.08E-47 T 14-10-2018 TSH58p_05525 2b32c109fb9595e981d590bc1a943ac1 430 Gene3D G3DSA:3.40.50.620 5 223 3.4E-65 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_05525 2b32c109fb9595e981d590bc1a943ac1 430 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 4 284 19.802 T 14-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 TSH58p_05525 2b32c109fb9595e981d590bc1a943ac1 430 Pfam PF01171 PP-loop family 13 191 2.7E-50 T 14-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 TSH58p_05525 2b32c109fb9595e981d590bc1a943ac1 430 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 13 191 2.8E-45 T 14-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 TSH58p_18975 5a77dbfba45c296141a491939fc3da0a 263 SUPERFAMILY SSF53474 15 260 1.17E-43 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_18975 5a77dbfba45c296141a491939fc3da0a 263 Gene3D G3DSA:3.40.50.1820 3 260 1.5E-41 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_18975 5a77dbfba45c296141a491939fc3da0a 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 63 78 1.1E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_18975 5a77dbfba45c296141a491939fc3da0a 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 125 138 1.1E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_18975 5a77dbfba45c296141a491939fc3da0a 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 124 1.1E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_18975 5a77dbfba45c296141a491939fc3da0a 263 Pfam PF00561 alpha/beta hydrolase fold 36 140 6.8E-17 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_20625 4eff8baf580d2733ea1d83f424a0f5c4 303 SUPERFAMILY SSF53955 28 159 2.67E-32 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily TSH58p_20625 4eff8baf580d2733ea1d83f424a0f5c4 303 Gene3D G3DSA:1.10.530.10 30 163 8.9E-31 T 14-10-2018 TSH58p_20625 4eff8baf580d2733ea1d83f424a0f5c4 303 Pfam PF05036 Sporulation related domain 220 300 5.6E-9 T 14-10-2018 IPR007730 Sporulation-like domain GO:0042834 TSH58p_20625 4eff8baf580d2733ea1d83f424a0f5c4 303 Pfam PF01464 Transglycosylase SLT domain 37 146 2.4E-17 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 TSH58p_12720 1f3473eca61df84b99adc6def56cab9e 130 TIGRFAM TIGR02300 FYDLN_acid: TIGR02300 family protein 1 128 1.5E-22 T 14-10-2018 IPR012644 Conserved hypothetical protein CHP02300, FYDLN acid TSH58p_12720 1f3473eca61df84b99adc6def56cab9e 130 Pfam PF09538 Protein of unknown function (FYDLN_acid) 2 107 4.2E-25 T 14-10-2018 IPR012644 Conserved hypothetical protein CHP02300, FYDLN acid TSH58p_05110 e46d33aaa68dd393e1b1e61672ca9c2f 265 Gene3D G3DSA:3.20.20.150 1 259 2.1E-82 T 14-10-2018 TSH58p_05110 e46d33aaa68dd393e1b1e61672ca9c2f 265 Pfam PF01261 Xylose isomerase-like TIM barrel 21 219 5.0E-34 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TSH58p_05110 e46d33aaa68dd393e1b1e61672ca9c2f 265 PIRSF PIRSF006241 1 259 5.9E-95 T 14-10-2018 IPR026040 Hydroxypyruvate isomerase-like TSH58p_05110 e46d33aaa68dd393e1b1e61672ca9c2f 265 TIGRFAM TIGR03234 OH-pyruv-isom: hydroxypyruvate isomerase 2 254 8.1E-119 T 14-10-2018 IPR017643 Hydroxypyruvate isomerase KEGG: 00630+5.3.1.22 TSH58p_05110 e46d33aaa68dd393e1b1e61672ca9c2f 265 SUPERFAMILY SSF51658 1 256 5.76E-90 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily TSH58p_28610 3d5b337a6d4da184416b5eec18fc53db 306 SUPERFAMILY SSF53850 26 304 6.51E-53 T 14-10-2018 TSH58p_28610 3d5b337a6d4da184416b5eec18fc53db 306 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 26 300 9.3E-51 T 14-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 TSH58p_28610 3d5b337a6d4da184416b5eec18fc53db 306 Gene3D G3DSA:3.40.190.10 29 303 3.1E-91 T 14-10-2018 TSH58p_28610 3d5b337a6d4da184416b5eec18fc53db 306 Gene3D G3DSA:3.40.190.120 130 243 3.1E-91 T 14-10-2018 TSH58p_29360 4861fde4e9e227ab1484e58d4b35d346 254 Pfam PF08241 Methyltransferase domain 48 144 5.3E-24 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TSH58p_29360 4861fde4e9e227ab1484e58d4b35d346 254 Gene3D G3DSA:3.40.50.150 24 242 9.3E-58 T 14-10-2018 TSH58p_29360 4861fde4e9e227ab1484e58d4b35d346 254 SUPERFAMILY SSF53335 12 242 2.32E-46 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_16525 c091657cf25181c3401500a2ecf79dc5 168 SUPERFAMILY SSF46785 30 161 1.45E-29 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_16525 c091657cf25181c3401500a2ecf79dc5 168 Pfam PF01475 Ferric uptake regulator family 36 156 1.2E-12 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 TSH58p_16525 c091657cf25181c3401500a2ecf79dc5 168 Gene3D G3DSA:3.30.1490.190 111 167 2.2E-17 T 14-10-2018 TSH58p_16525 c091657cf25181c3401500a2ecf79dc5 168 Gene3D G3DSA:1.10.10.10 19 107 8.1E-33 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_12820 d6da624de7d96102162832f185f81df1 621 Pfam PF06213 Cobalamin biosynthesis protein CobT 5 276 1.3E-91 T 14-10-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 TSH58p_12820 d6da624de7d96102162832f185f81df1 621 SMART SM00327 404 614 0.0035 T 14-10-2018 IPR002035 von Willebrand factor, type A TSH58p_12820 d6da624de7d96102162832f185f81df1 621 PIRSF PIRSF031715 1 618 1.2E-257 T 14-10-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 TSH58p_12820 d6da624de7d96102162832f185f81df1 621 Gene3D G3DSA:3.40.50.410 405 608 2.5E-7 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TSH58p_12820 d6da624de7d96102162832f185f81df1 621 SUPERFAMILY SSF53300 407 601 1.48E-15 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TSH58p_12820 d6da624de7d96102162832f185f81df1 621 Pfam PF11775 Cobalamin biosynthesis protein CobT VWA domain 393 610 3.9E-112 T 14-10-2018 IPR025861 Cobalamin biosynthesis protein CobT VWA domain KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 TSH58p_12820 d6da624de7d96102162832f185f81df1 621 TIGRFAM TIGR01651 CobT: cobaltochelatase, CobT subunit 9 611 6.7E-261 T 14-10-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 TSH58p_07385 962be3f80d3b56881867f8c97f05a259 276 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 25 185 4.6E-72 T 14-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 TSH58p_07385 962be3f80d3b56881867f8c97f05a259 276 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 91 127 1.2E-4 T 14-10-2018 IPR001451 Hexapeptide repeat TSH58p_07385 962be3f80d3b56881867f8c97f05a259 276 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 137 169 8.7E-6 T 14-10-2018 IPR001451 Hexapeptide repeat TSH58p_07385 962be3f80d3b56881867f8c97f05a259 276 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 145 173 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 TSH58p_07385 962be3f80d3b56881867f8c97f05a259 276 SUPERFAMILY SSF51161 21 187 1.39E-49 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily TSH58p_07385 962be3f80d3b56881867f8c97f05a259 276 Gene3D G3DSA:2.160.10.10 86 201 5.2E-34 T 14-10-2018 TSH58p_07385 962be3f80d3b56881867f8c97f05a259 276 PIRSF PIRSF000441 19 248 7.6E-82 T 14-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 TSH58p_07385 962be3f80d3b56881867f8c97f05a259 276 Gene3D G3DSA:1.10.3130.10 11 85 3.6E-20 T 14-10-2018 TSH58p_26385 3287f93e0d8943a7f09c142915fda7e2 496 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 192 205 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 TSH58p_26385 3287f93e0d8943a7f09c142915fda7e2 496 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 381 390 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site TSH58p_26385 3287f93e0d8943a7f09c142915fda7e2 496 SMART SM00448 27 138 1.4E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_26385 3287f93e0d8943a7f09c142915fda7e2 496 Pfam PF00072 Response regulator receiver domain 29 138 5.1E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_26385 3287f93e0d8943a7f09c142915fda7e2 496 Pfam PF02954 Bacterial regulatory protein, Fis family 454 490 3.9E-12 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_26385 3287f93e0d8943a7f09c142915fda7e2 496 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 254 269 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 TSH58p_26385 3287f93e0d8943a7f09c142915fda7e2 496 SUPERFAMILY SSF52540 167 399 1.04E-69 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_26385 3287f93e0d8943a7f09c142915fda7e2 496 SMART SM00382 188 331 3.5E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_26385 3287f93e0d8943a7f09c142915fda7e2 496 SUPERFAMILY SSF52172 25 213 2.42E-41 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_26385 3287f93e0d8943a7f09c142915fda7e2 496 SUPERFAMILY SSF46689 445 495 3.99E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_26385 3287f93e0d8943a7f09c142915fda7e2 496 Pfam PF00158 Sigma-54 interaction domain 168 334 5.4E-69 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 TSH58p_26385 3287f93e0d8943a7f09c142915fda7e2 496 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 477 496 9.5E-6 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_26385 3287f93e0d8943a7f09c142915fda7e2 496 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 460 477 9.5E-6 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_26385 3287f93e0d8943a7f09c142915fda7e2 496 Gene3D G3DSA:1.10.10.60 449 491 5.8E-14 T 14-10-2018 TSH58p_26385 3287f93e0d8943a7f09c142915fda7e2 496 Gene3D G3DSA:3.40.50.2300 24 157 5.3E-31 T 14-10-2018 TSH58p_26385 3287f93e0d8943a7f09c142915fda7e2 496 Gene3D G3DSA:1.10.8.60 339 403 1.1E-15 T 14-10-2018 TSH58p_26385 3287f93e0d8943a7f09c142915fda7e2 496 Gene3D G3DSA:3.40.50.300 158 338 6.6E-67 T 14-10-2018 TSH58p_25740 2a0ede240737af8f094a3d62f8e22f05 211 SUPERFAMILY SSF54862 1 180 1.26E-50 T 14-10-2018 TSH58p_25740 2a0ede240737af8f094a3d62f8e22f05 211 Gene3D G3DSA:3.30.70.20 61 118 1.7E-34 T 14-10-2018 TSH58p_25740 2a0ede240737af8f094a3d62f8e22f05 211 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 87 98 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_25740 2a0ede240737af8f094a3d62f8e22f05 211 Pfam PF13247 4Fe-4S dicluster domain 52 123 4.3E-10 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_25740 2a0ede240737af8f094a3d62f8e22f05 211 Gene3D G3DSA:3.30.70.20 5 167 1.7E-34 T 14-10-2018 TSH58p_25740 2a0ede240737af8f094a3d62f8e22f05 211 PRINTS PR00354 7Fe ferredoxin signature 65 75 4.6E-5 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TSH58p_25740 2a0ede240737af8f094a3d62f8e22f05 211 PRINTS PR00354 7Fe ferredoxin signature 55 65 4.6E-5 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TSH58p_25740 2a0ede240737af8f094a3d62f8e22f05 211 PRINTS PR00354 7Fe ferredoxin signature 82 99 4.6E-5 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TSH58p_15070 388afe66586690676b213e2917fc53da 283 Pfam PF00588 SpoU rRNA Methylase family 137 277 2.1E-38 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TSH58p_15070 388afe66586690676b213e2917fc53da 283 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 42 281 5.1E-60 T 14-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 TSH58p_15070 388afe66586690676b213e2917fc53da 283 SUPERFAMILY SSF75217 121 281 3.66E-45 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases TSH58p_15070 388afe66586690676b213e2917fc53da 283 SMART SM00967 42 121 1.3E-13 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 TSH58p_15070 388afe66586690676b213e2917fc53da 283 Gene3D G3DSA:3.40.1280.10 120 283 1.1E-52 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TSH58p_15070 388afe66586690676b213e2917fc53da 283 Gene3D G3DSA:3.30.1330.30 34 117 1.5E-6 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like TSH58p_15070 388afe66586690676b213e2917fc53da 283 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 42 120 1.4E-10 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 TSH58p_15070 388afe66586690676b213e2917fc53da 283 SUPERFAMILY SSF55315 40 118 1.6E-9 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like TSH58p_09620 e04c8e14c949612a05b0ea04213712fa 354 SMART SM00448 5 120 2.8E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_09620 e04c8e14c949612a05b0ea04213712fa 354 Gene3D G3DSA:3.40.50.180 152 348 1.4E-68 T 14-10-2018 IPR035909 Methylesterase CheB, C-terminal TSH58p_09620 e04c8e14c949612a05b0ea04213712fa 354 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 5 344 38.316 T 14-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 TSH58p_09620 e04c8e14c949612a05b0ea04213712fa 354 Gene3D G3DSA:3.40.50.2300 2 137 3.0E-31 T 14-10-2018 TSH58p_09620 e04c8e14c949612a05b0ea04213712fa 354 SUPERFAMILY SSF52172 4 110 1.02E-28 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_09620 e04c8e14c949612a05b0ea04213712fa 354 SUPERFAMILY SSF52738 158 343 1.96E-65 T 14-10-2018 IPR035909 Methylesterase CheB, C-terminal TSH58p_09620 e04c8e14c949612a05b0ea04213712fa 354 Pfam PF00072 Response regulator receiver domain 7 109 7.5E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_09620 e04c8e14c949612a05b0ea04213712fa 354 Pfam PF01339 CheB methylesterase 161 338 7.4E-56 T 14-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 TSH58p_09620 e04c8e14c949612a05b0ea04213712fa 354 PIRSF PIRSF000876 2 348 2.2E-128 T 14-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 TSH58p_19670 1f1f09b7c0dc11a788edbfbfddfa29c7 295 Gene3D G3DSA:1.10.10.10 36 106 1.1E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_19670 1f1f09b7c0dc11a788edbfbfddfa29c7 295 SUPERFAMILY SSF46785 40 110 7.39E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_19670 1f1f09b7c0dc11a788edbfbfddfa29c7 295 SUPERFAMILY SSF55781 119 283 1.83E-44 T 14-10-2018 TSH58p_19670 1f1f09b7c0dc11a788edbfbfddfa29c7 295 SMART SM00346 41 127 1.8E-5 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TSH58p_19670 1f1f09b7c0dc11a788edbfbfddfa29c7 295 Pfam PF01614 Bacterial transcriptional regulator 158 279 6.2E-29 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal TSH58p_19670 1f1f09b7c0dc11a788edbfbfddfa29c7 295 Gene3D G3DSA:3.30.450.40 113 289 2.2E-51 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_19670 1f1f09b7c0dc11a788edbfbfddfa29c7 295 Pfam PF09339 IclR helix-turn-helix domain 40 88 3.9E-16 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TSH58p_31395 f3bb6676f66e5a336b28b4bb8f59039a 836 Pfam PF07715 TonB-dependent Receptor Plug Domain 182 290 2.4E-23 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain TSH58p_31395 f3bb6676f66e5a336b28b4bb8f59039a 836 Gene3D G3DSA:2.40.170.20 301 836 3.9E-148 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily TSH58p_31395 f3bb6676f66e5a336b28b4bb8f59039a 836 SMART SM00965 89 140 7.6E-11 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 TSH58p_31395 f3bb6676f66e5a336b28b4bb8f59039a 836 Gene3D G3DSA:2.170.130.10 159 300 8.2E-44 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily TSH58p_31395 f3bb6676f66e5a336b28b4bb8f59039a 836 SUPERFAMILY SSF56935 143 836 1.99E-146 T 14-10-2018 TSH58p_31395 f3bb6676f66e5a336b28b4bb8f59039a 836 Pfam PF00593 TonB dependent receptor 381 835 2.2E-65 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel TSH58p_31395 f3bb6676f66e5a336b28b4bb8f59039a 836 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 183 834 1.7E-129 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 TSH58p_31395 f3bb6676f66e5a336b28b4bb8f59039a 836 Pfam PF07660 Secretin and TonB N terminus short domain 93 139 7.0E-7 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 TSH58p_31395 f3bb6676f66e5a336b28b4bb8f59039a 836 Gene3D G3DSA:3.55.50.30 60 158 7.0E-28 T 14-10-2018 TSH58p_23070 b6285676251c7f4185f14154895c29db 296 Gene3D G3DSA:3.10.129.10 175 295 5.8E-14 T 14-10-2018 TSH58p_23070 b6285676251c7f4185f14154895c29db 296 SUPERFAMILY SSF54637 89 165 1.41E-10 T 14-10-2018 IPR029069 HotDog domain superfamily TSH58p_23070 b6285676251c7f4185f14154895c29db 296 Pfam PF13452 N-terminal half of MaoC dehydratase 82 142 3.3E-12 T 14-10-2018 IPR039569 N-terminal of MaoC-like dehydratase Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-9033241|Reactome: R-HSA-9033500 TSH58p_23070 b6285676251c7f4185f14154895c29db 296 SUPERFAMILY SSF54637 178 295 3.29E-15 T 14-10-2018 IPR029069 HotDog domain superfamily TSH58p_23070 b6285676251c7f4185f14154895c29db 296 Gene3D G3DSA:3.10.129.10 40 165 1.1E-17 T 14-10-2018 TSH58p_16230 ff4fae7bc958128a2e850b88616d2adc 147 Gene3D G3DSA:3.20.20.70 11 109 1.6E-5 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_01985 bd887055661abce5556c5b528640984a 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 2.6E-15 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSH58p_01985 bd887055661abce5556c5b528640984a 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 2.6E-15 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSH58p_01985 bd887055661abce5556c5b528640984a 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 2.6E-15 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSH58p_01985 bd887055661abce5556c5b528640984a 153 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 51 9.8E-17 T 14-10-2018 TSH58p_01985 bd887055661abce5556c5b528640984a 153 Gene3D G3DSA:3.30.70.920 58 140 4.2E-26 T 14-10-2018 TSH58p_01985 bd887055661abce5556c5b528640984a 153 SUPERFAMILY SSF54909 64 153 7.64E-25 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel TSH58p_01985 bd887055661abce5556c5b528640984a 153 SMART SM00344 4 113 6.3E-48 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TSH58p_01985 bd887055661abce5556c5b528640984a 153 SUPERFAMILY SSF46785 3 93 2.56E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_01985 bd887055661abce5556c5b528640984a 153 Pfam PF01037 Lrp/AsnC ligand binding domain 70 144 1.2E-23 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TSH58p_01985 bd887055661abce5556c5b528640984a 153 Gene3D G3DSA:1.10.10.10 1 57 6.6E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_19850 6e38721ea2b9bcf610f7f50b1f2c44fd 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 8.2E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_19850 6e38721ea2b9bcf610f7f50b1f2c44fd 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 8.2E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_19850 6e38721ea2b9bcf610f7f50b1f2c44fd 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 8.2E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_19850 6e38721ea2b9bcf610f7f50b1f2c44fd 310 Pfam PF03466 LysR substrate binding domain 94 295 1.9E-39 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_19850 6e38721ea2b9bcf610f7f50b1f2c44fd 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 70 3.3E-23 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_19850 6e38721ea2b9bcf610f7f50b1f2c44fd 310 SUPERFAMILY SSF46785 6 116 6.93E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_19850 6e38721ea2b9bcf610f7f50b1f2c44fd 310 Gene3D G3DSA:3.40.190.10 166 263 4.0E-58 T 14-10-2018 TSH58p_19850 6e38721ea2b9bcf610f7f50b1f2c44fd 310 Gene3D G3DSA:1.10.10.10 10 98 1.5E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_19850 6e38721ea2b9bcf610f7f50b1f2c44fd 310 SUPERFAMILY SSF53850 95 297 1.99E-40 T 14-10-2018 TSH58p_19850 6e38721ea2b9bcf610f7f50b1f2c44fd 310 Gene3D G3DSA:3.40.190.10 106 291 4.0E-58 T 14-10-2018 TSH58p_18660 4788a07257874b3e84acdbc38d992bc9 294 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 95 116 6.3E-38 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TSH58p_18660 4788a07257874b3e84acdbc38d992bc9 294 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 198 215 6.3E-38 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TSH58p_18660 4788a07257874b3e84acdbc38d992bc9 294 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 240 258 6.3E-38 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TSH58p_18660 4788a07257874b3e84acdbc38d992bc9 294 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 159 179 6.3E-38 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TSH58p_18660 4788a07257874b3e84acdbc38d992bc9 294 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 136 158 6.3E-38 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TSH58p_18660 4788a07257874b3e84acdbc38d992bc9 294 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 14 31 6.3E-38 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TSH58p_18660 4788a07257874b3e84acdbc38d992bc9 294 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 13 258 1.1E-75 T 14-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region TSH58p_18660 4788a07257874b3e84acdbc38d992bc9 294 Gene3D G3DSA:2.120.10.30 1 293 9.1E-95 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TSH58p_18660 4788a07257874b3e84acdbc38d992bc9 294 SUPERFAMILY SSF63829 5 290 6.54E-66 T 14-10-2018 TSH58p_24685 f03d5a28ae7140676a5bf4761a37b503 405 Hamap MF_01689 Ornithine aminotransferase [rocD]. 5 400 61.61 T 14-10-2018 IPR034757 Ornithine aminotransferase, bacterial type GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922 TSH58p_24685 f03d5a28ae7140676a5bf4761a37b503 405 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 224 261 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSH58p_24685 f03d5a28ae7140676a5bf4761a37b503 405 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 7 398 3.5E-163 T 14-10-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 TSH58p_24685 f03d5a28ae7140676a5bf4761a37b503 405 Pfam PF00202 Aminotransferase class-III 17 399 6.8E-121 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSH58p_24685 f03d5a28ae7140676a5bf4761a37b503 405 SUPERFAMILY SSF53383 4 399 1.81E-121 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_24685 f03d5a28ae7140676a5bf4761a37b503 405 PIRSF PIRSF000521 13 158 7.1E-8 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSH58p_24685 f03d5a28ae7140676a5bf4761a37b503 405 PIRSF PIRSF000521 176 402 4.6E-36 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSH58p_24685 f03d5a28ae7140676a5bf4761a37b503 405 Gene3D G3DSA:3.90.1150.10 14 389 4.8E-144 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_24685 f03d5a28ae7140676a5bf4761a37b503 405 Gene3D G3DSA:3.40.640.10 59 309 4.8E-144 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_26890 f54e77bd7b832dbfb8546a4f7e362e6c 594 SUPERFAMILY SSF161098 22 286 1.4E-48 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_26890 f54e77bd7b832dbfb8546a4f7e362e6c 594 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 278 6.6E-7 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_26890 f54e77bd7b832dbfb8546a4f7e362e6c 594 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 413 586 3.6E-9 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_26890 f54e77bd7b832dbfb8546a4f7e362e6c 594 SUPERFAMILY SSF161098 341 592 1.31E-48 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_26890 f54e77bd7b832dbfb8546a4f7e362e6c 594 Gene3D G3DSA:1.10.3720.10 25 291 2.3E-53 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_26890 f54e77bd7b832dbfb8546a4f7e362e6c 594 Gene3D G3DSA:1.10.3720.10 339 593 2.0E-47 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_15480 7237289e823aa8f9022aa6d6f7d8379a 111 Pfam PF01312 FlhB HrpN YscU SpaS Family 16 89 2.0E-17 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 TSH58p_15480 7237289e823aa8f9022aa6d6f7d8379a 111 SUPERFAMILY SSF160544 15 93 3.01E-21 T 14-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal TSH58p_15480 7237289e823aa8f9022aa6d6f7d8379a 111 Gene3D G3DSA:3.40.1690.10 13 94 3.9E-23 T 14-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal TSH58p_15595 b74d7890aad2206728330f071c61c3cd 481 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 228 247 - T 14-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 TSH58p_15595 b74d7890aad2206728330f071c61c3cd 481 TIGRFAM TIGR02924 ICDH_alpha: isocitrate dehydrogenase 5 478 8.1E-203 T 14-10-2018 IPR014273 Isocitrate dehydrogenase, alphaproteobacteria-type GO:0004450|GO:0006097|GO:0006099|GO:0046872|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 TSH58p_15595 b74d7890aad2206728330f071c61c3cd 481 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 7 337 1.0E-92 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 TSH58p_15595 b74d7890aad2206728330f071c61c3cd 481 Gene3D G3DSA:3.40.718.10 1 368 1.9E-130 T 14-10-2018 TSH58p_15595 b74d7890aad2206728330f071c61c3cd 481 Gene3D G3DSA:3.30.70.1570 374 481 3.4E-29 T 14-10-2018 TSH58p_15595 b74d7890aad2206728330f071c61c3cd 481 SMART SM01329 6 337 4.5E-152 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 TSH58p_15595 b74d7890aad2206728330f071c61c3cd 481 SUPERFAMILY SSF53659 3 341 6.91E-114 T 14-10-2018 TSH58p_10410 70877576a14879c65d1542901c5f8150 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 14-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 TSH58p_10410 70877576a14879c65d1542901c5f8150 112 SUPERFAMILY SSF54913 1 112 6.99E-45 T 14-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TSH58p_10410 70877576a14879c65d1542901c5f8150 112 PIRSF PIRSF039144 1 112 5.4E-54 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TSH58p_10410 70877576a14879c65d1542901c5f8150 112 Gene3D G3DSA:3.30.70.120 1 112 1.3E-46 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TSH58p_10410 70877576a14879c65d1542901c5f8150 112 PRINTS PR00340 P-II protein signature 83 103 2.2E-42 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TSH58p_10410 70877576a14879c65d1542901c5f8150 112 PRINTS PR00340 P-II protein signature 2 17 2.2E-42 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TSH58p_10410 70877576a14879c65d1542901c5f8150 112 PRINTS PR00340 P-II protein signature 52 75 2.2E-42 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TSH58p_10410 70877576a14879c65d1542901c5f8150 112 PRINTS PR00340 P-II protein signature 23 41 2.2E-42 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TSH58p_10410 70877576a14879c65d1542901c5f8150 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 1.1E-43 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TSH58p_10410 70877576a14879c65d1542901c5f8150 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 14-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 TSH58p_10410 70877576a14879c65d1542901c5f8150 112 SMART SM00938 4 105 8.8E-66 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TSH58p_00215 ddd883f1f20a2846dd8baef312f6a495 241 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 28 171 8.8E-45 T 14-10-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related TSH58p_00215 ddd883f1f20a2846dd8baef312f6a495 241 Gene3D G3DSA:2.30.110.10 10 227 6.7E-69 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TSH58p_00215 ddd883f1f20a2846dd8baef312f6a495 241 SUPERFAMILY SSF50475 9 189 1.42E-57 T 14-10-2018 TSH58p_05005 2a8fcbfc26ac1d371178a7e1de531e0e 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 25 99 4.0E-33 T 14-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 TSH58p_05005 2a8fcbfc26ac1d371178a7e1de531e0e 100 SUPERFAMILY SSF54111 1 100 6.02E-46 T 14-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 TSH58p_05005 2a8fcbfc26ac1d371178a7e1de531e0e 100 Pfam PF00547 Urease, gamma subunit 1 99 1.1E-47 T 14-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 TSH58p_05005 2a8fcbfc26ac1d371178a7e1de531e0e 100 PIRSF PIRSF001223 1 100 2.0E-51 T 14-10-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 TSH58p_05005 2a8fcbfc26ac1d371178a7e1de531e0e 100 Gene3D G3DSA:3.30.280.10 1 100 3.7E-48 T 14-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 TSH58p_05005 2a8fcbfc26ac1d371178a7e1de531e0e 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 34.78 T 14-10-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 TSH58p_05005 2a8fcbfc26ac1d371178a7e1de531e0e 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 100 1.8E-48 T 14-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 TSH58p_25830 5b112030cba79340b16802b1f1b09475 487 Gene3D G3DSA:3.50.50.60 256 406 9.2E-44 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_25830 5b112030cba79340b16802b1f1b09475 487 PRINTS PR00419 Adrenodoxin reductase family signature 327 340 1.6E-32 T 14-10-2018 TSH58p_25830 5b112030cba79340b16802b1f1b09475 487 PRINTS PR00419 Adrenodoxin reductase family signature 293 307 1.6E-32 T 14-10-2018 TSH58p_25830 5b112030cba79340b16802b1f1b09475 487 PRINTS PR00419 Adrenodoxin reductase family signature 150 172 1.6E-32 T 14-10-2018 TSH58p_25830 5b112030cba79340b16802b1f1b09475 487 PRINTS PR00419 Adrenodoxin reductase family signature 173 186 1.6E-32 T 14-10-2018 TSH58p_25830 5b112030cba79340b16802b1f1b09475 487 PRINTS PR00419 Adrenodoxin reductase family signature 215 225 1.6E-32 T 14-10-2018 TSH58p_25830 5b112030cba79340b16802b1f1b09475 487 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 25 136 2.8E-37 T 14-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 TSH58p_25830 5b112030cba79340b16802b1f1b09475 487 Gene3D G3DSA:1.10.1060.10 9 147 5.1E-34 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSH58p_25830 5b112030cba79340b16802b1f1b09475 487 SUPERFAMILY SSF51971 148 407 7.06E-63 T 14-10-2018 TSH58p_25830 5b112030cba79340b16802b1f1b09475 487 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 151 463 5.4E-28 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSH58p_25830 5b112030cba79340b16802b1f1b09475 487 TIGRFAM TIGR01318 gltD_gamma_fam: glutamate synthase, small subunit 9 473 3.2E-155 T 14-10-2018 IPR006006 Glutamate synthase, NADH/NADPH, small subunit 2 GO:0006537|GO:0016639 TSH58p_25830 5b112030cba79340b16802b1f1b09475 487 SUPERFAMILY SSF46548 6 159 4.71E-37 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSH58p_25830 5b112030cba79340b16802b1f1b09475 487 Gene3D G3DSA:3.40.50.720 148 255 1.0E-10 T 14-10-2018 TSH58p_16630 e8edd389ebe5f803cb88f9d172941c70 868 Pfam PF03781 Sulfatase-modifying factor enzyme 1 640 865 7.4E-56 T 14-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 TSH58p_16630 e8edd389ebe5f803cb88f9d172941c70 868 Pfam PF00656 Caspase domain 68 295 4.4E-30 T 14-10-2018 TSH58p_16630 e8edd389ebe5f803cb88f9d172941c70 868 SUPERFAMILY SSF52129 49 297 1.27E-45 T 14-10-2018 IPR029030 Caspase-like domain superfamily TSH58p_16630 e8edd389ebe5f803cb88f9d172941c70 868 Gene3D G3DSA:3.90.1580.10 627 867 7.4E-59 T 14-10-2018 TSH58p_16630 e8edd389ebe5f803cb88f9d172941c70 868 Gene3D G3DSA:3.40.50.1460 52 297 6.0E-52 T 14-10-2018 TSH58p_16630 e8edd389ebe5f803cb88f9d172941c70 868 SUPERFAMILY SSF56436 640 867 7.06E-66 T 14-10-2018 IPR016187 C-type lectin fold TSH58p_28220 c1eaf76f943eaef4b9dd1f5dd983fd5b 170 Gene3D G3DSA:1.10.10.10 8 151 6.1E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_28220 c1eaf76f943eaef4b9dd1f5dd983fd5b 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 62 78 7.9E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_28220 c1eaf76f943eaef4b9dd1f5dd983fd5b 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 79 94 7.9E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_28220 c1eaf76f943eaef4b9dd1f5dd983fd5b 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 98 114 7.9E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_28220 c1eaf76f943eaef4b9dd1f5dd983fd5b 170 SUPERFAMILY SSF46785 22 151 1.2E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_28220 c1eaf76f943eaef4b9dd1f5dd983fd5b 170 Pfam PF12802 MarR family 44 102 9.3E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_28220 c1eaf76f943eaef4b9dd1f5dd983fd5b 170 SMART SM00347 38 138 1.4E-15 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_28220 c1eaf76f943eaef4b9dd1f5dd983fd5b 170 ProSitePatterns PS01117 MarR-type HTH domain signature. 77 111 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site TSH58p_11390 48b541b7afd5be292b35046a2bd089e3 511 Gene3D G3DSA:1.10.150.20 351 416 5.7E-23 T 14-10-2018 TSH58p_11390 48b541b7afd5be292b35046a2bd089e3 511 SUPERFAMILY SSF54814 276 339 1.05E-17 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TSH58p_11390 48b541b7afd5be292b35046a2bd089e3 511 SUPERFAMILY SSF47794 427 491 2.04E-9 T 14-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 TSH58p_11390 48b541b7afd5be292b35046a2bd089e3 511 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 1 407 30.577 T 14-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 TSH58p_11390 48b541b7afd5be292b35046a2bd089e3 511 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 362 410 7.1E-19 T 14-10-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication TSH58p_11390 48b541b7afd5be292b35046a2bd089e3 511 Pfam PF14520 Helix-hairpin-helix domain 366 405 1.8E-4 T 14-10-2018 TSH58p_11390 48b541b7afd5be292b35046a2bd089e3 511 SUPERFAMILY SSF69705 2 123 4.19E-40 T 14-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 TSH58p_11390 48b541b7afd5be292b35046a2bd089e3 511 SMART SM00322 227 299 2.1 T 14-10-2018 IPR004087 K Homology domain GO:0003676 TSH58p_11390 48b541b7afd5be292b35046a2bd089e3 511 SMART SM00322 300 411 0.037 T 14-10-2018 IPR004087 K Homology domain GO:0003676 TSH58p_11390 48b541b7afd5be292b35046a2bd089e3 511 SMART SM00316 131 197 1.2E-8 T 14-10-2018 IPR022967 RNA-binding domain, S1 TSH58p_11390 48b541b7afd5be292b35046a2bd089e3 511 Gene3D G3DSA:2.40.50.140 133 195 5.4E-24 T 14-10-2018 TSH58p_11390 48b541b7afd5be292b35046a2bd089e3 511 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 2 339 4.9E-137 T 14-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 TSH58p_11390 48b541b7afd5be292b35046a2bd089e3 511 SUPERFAMILY SSF47794 351 411 1.1E-16 T 14-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 TSH58p_11390 48b541b7afd5be292b35046a2bd089e3 511 Gene3D G3DSA:1.10.150.20 429 489 1.3E-12 T 14-10-2018 TSH58p_11390 48b541b7afd5be292b35046a2bd089e3 511 Gene3D G3DSA:3.30.300.20 275 343 8.5E-28 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta TSH58p_11390 48b541b7afd5be292b35046a2bd089e3 511 Gene3D G3DSA:3.30.1480.10 1 125 1.2E-42 T 14-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 TSH58p_11390 48b541b7afd5be292b35046a2bd089e3 511 Pfam PF13184 NusA-like KH domain 227 293 5.3E-28 T 14-10-2018 IPR025249 KH domain, NusA-like GO:0003723 TSH58p_11390 48b541b7afd5be292b35046a2bd089e3 511 Pfam PF08529 NusA N-terminal domain 2 122 1.2E-37 T 14-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 TSH58p_11390 48b541b7afd5be292b35046a2bd089e3 511 SUPERFAMILY SSF50249 129 196 2.42E-19 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_11390 48b541b7afd5be292b35046a2bd089e3 511 Pfam PF00575 S1 RNA binding domain 129 191 5.5E-6 T 14-10-2018 IPR003029 S1 domain GO:0003676 TSH58p_11390 48b541b7afd5be292b35046a2bd089e3 511 SUPERFAMILY SSF54814 197 274 2.49E-31 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TSH58p_11390 48b541b7afd5be292b35046a2bd089e3 511 Gene3D G3DSA:3.30.300.20 196 274 1.2E-34 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta TSH58p_01795 958b774e00789755964c47a7900872aa 262 Gene3D G3DSA:1.10.10.10 3 82 6.5E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_01795 958b774e00789755964c47a7900872aa 262 SUPERFAMILY SSF55781 77 259 1.11E-46 T 14-10-2018 TSH58p_01795 958b774e00789755964c47a7900872aa 262 SMART SM00346 11 101 6.9E-24 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TSH58p_01795 958b774e00789755964c47a7900872aa 262 Pfam PF09339 IclR helix-turn-helix domain 13 61 2.3E-15 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TSH58p_01795 958b774e00789755964c47a7900872aa 262 Gene3D G3DSA:3.30.450.40 83 260 1.3E-48 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_01795 958b774e00789755964c47a7900872aa 262 Pfam PF01614 Bacterial transcriptional regulator 128 254 4.5E-29 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal TSH58p_01795 958b774e00789755964c47a7900872aa 262 SUPERFAMILY SSF46785 13 84 6.94E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_31505 7395e9ddf8c3296c4c5757d1a8eda235 534 Gene3D G3DSA:3.40.250.10 383 485 2.1E-13 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily TSH58p_31505 7395e9ddf8c3296c4c5757d1a8eda235 534 SUPERFAMILY SSF52821 384 530 1.3E-21 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily TSH58p_31505 7395e9ddf8c3296c4c5757d1a8eda235 534 Gene3D G3DSA:3.40.250.10 130 237 2.8E-21 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily TSH58p_31505 7395e9ddf8c3296c4c5757d1a8eda235 534 SUPERFAMILY SSF52821 14 127 3.8E-23 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily TSH58p_31505 7395e9ddf8c3296c4c5757d1a8eda235 534 SUPERFAMILY SSF52821 110 237 1.83E-29 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily TSH58p_31505 7395e9ddf8c3296c4c5757d1a8eda235 534 Pfam PF00581 Rhodanese-like domain 280 361 1.0E-5 T 14-10-2018 IPR001763 Rhodanese-like domain TSH58p_31505 7395e9ddf8c3296c4c5757d1a8eda235 534 Pfam PF00581 Rhodanese-like domain 19 104 4.1E-6 T 14-10-2018 IPR001763 Rhodanese-like domain TSH58p_31505 7395e9ddf8c3296c4c5757d1a8eda235 534 Pfam PF00581 Rhodanese-like domain 134 228 6.3E-7 T 14-10-2018 IPR001763 Rhodanese-like domain TSH58p_31505 7395e9ddf8c3296c4c5757d1a8eda235 534 Gene3D G3DSA:3.40.250.10 19 113 3.5E-16 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily TSH58p_31505 7395e9ddf8c3296c4c5757d1a8eda235 534 SUPERFAMILY SSF52821 259 360 3.8E-17 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily TSH58p_31505 7395e9ddf8c3296c4c5757d1a8eda235 534 SMART SM00450 270 370 4.3E-5 T 14-10-2018 IPR001763 Rhodanese-like domain TSH58p_31505 7395e9ddf8c3296c4c5757d1a8eda235 534 SMART SM00450 134 232 4.5E-6 T 14-10-2018 IPR001763 Rhodanese-like domain TSH58p_31505 7395e9ddf8c3296c4c5757d1a8eda235 534 SMART SM00450 386 479 0.0098 T 14-10-2018 IPR001763 Rhodanese-like domain TSH58p_31505 7395e9ddf8c3296c4c5757d1a8eda235 534 SMART SM00450 11 108 1.8E-10 T 14-10-2018 IPR001763 Rhodanese-like domain TSH58p_31505 7395e9ddf8c3296c4c5757d1a8eda235 534 Gene3D G3DSA:3.40.250.10 267 359 2.3E-16 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily TSH58p_02290 827e330f9a5b383a07a37c371fa7f793 923 SUPERFAMILY SSF55874 732 896 5.63E-41 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_02290 827e330f9a5b383a07a37c371fa7f793 923 SUPERFAMILY SSF55781 515 667 1.96E-6 T 14-10-2018 TSH58p_02290 827e330f9a5b383a07a37c371fa7f793 923 Gene3D G3DSA:3.30.450.40 516 666 3.9E-35 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_02290 827e330f9a5b383a07a37c371fa7f793 923 PRINTS PR00344 Bacterial sensor protein C-terminal signature 841 851 8.6E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_02290 827e330f9a5b383a07a37c371fa7f793 923 PRINTS PR00344 Bacterial sensor protein C-terminal signature 823 837 8.6E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_02290 827e330f9a5b383a07a37c371fa7f793 923 PRINTS PR00344 Bacterial sensor protein C-terminal signature 857 875 8.6E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_02290 827e330f9a5b383a07a37c371fa7f793 923 PRINTS PR00344 Bacterial sensor protein C-terminal signature 882 895 8.6E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_02290 827e330f9a5b383a07a37c371fa7f793 923 Gene3D G3DSA:3.40.50.620 241 378 4.0E-12 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_02290 827e330f9a5b383a07a37c371fa7f793 923 Gene3D G3DSA:1.20.120.620 403 506 2.1E-23 T 14-10-2018 IPR038318 KdpD, transmembrane domain superfamily TSH58p_02290 827e330f9a5b383a07a37c371fa7f793 923 SUPERFAMILY SSF52402 256 378 1.0E-12 T 14-10-2018 TSH58p_02290 827e330f9a5b383a07a37c371fa7f793 923 Gene3D G3DSA:1.10.287.130 667 741 1.8E-17 T 14-10-2018 TSH58p_02290 827e330f9a5b383a07a37c371fa7f793 923 SMART SM00388 674 742 2.3E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_02290 827e330f9a5b383a07a37c371fa7f793 923 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 788 896 8.6E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_02290 827e330f9a5b383a07a37c371fa7f793 923 Pfam PF00512 His Kinase A (phospho-acceptor) domain 675 742 1.7E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_02290 827e330f9a5b383a07a37c371fa7f793 923 Gene3D G3DSA:3.30.565.10 748 900 1.5E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_02290 827e330f9a5b383a07a37c371fa7f793 923 Pfam PF00582 Universal stress protein family 256 370 7.6E-8 T 14-10-2018 IPR006016 UspA TSH58p_02290 827e330f9a5b383a07a37c371fa7f793 923 Gene3D G3DSA:3.40.50.300 23 233 2.5E-101 T 14-10-2018 TSH58p_02290 827e330f9a5b383a07a37c371fa7f793 923 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 26 234 1.2E-99 T 14-10-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 TSH58p_02290 827e330f9a5b383a07a37c371fa7f793 923 Pfam PF13493 Domain of unknown function (DUF4118) 406 511 5.2E-28 T 14-10-2018 IPR025201 Sensor protein KdpD, transmembrane domain TSH58p_02290 827e330f9a5b383a07a37c371fa7f793 923 SUPERFAMILY SSF47384 668 742 5.49E-16 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_02290 827e330f9a5b383a07a37c371fa7f793 923 SUPERFAMILY SSF52540 17 226 1.0E-4 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_02290 827e330f9a5b383a07a37c371fa7f793 923 SMART SM00387 786 898 2.4E-37 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_02290 827e330f9a5b383a07a37c371fa7f793 923 Pfam PF13492 GAF domain 532 655 5.0E-14 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_29275 4b28ee351e94889e8bb4e2b6e60af99a 265 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 42 255 8.3E-46 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 TSH58p_29275 4b28ee351e94889e8bb4e2b6e60af99a 265 SUPERFAMILY SSF53187 40 255 2.23E-47 T 14-10-2018 TSH58p_29275 4b28ee351e94889e8bb4e2b6e60af99a 265 SMART SM00646 102 256 9.5E-40 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 TSH58p_29275 4b28ee351e94889e8bb4e2b6e60af99a 265 Gene3D G3DSA:3.40.630.40 38 262 3.0E-67 T 14-10-2018 TSH58p_00695 018758653184a974115b0b8608332631 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 253 3.8E-58 T 14-10-2018 TSH58p_00695 018758653184a974115b0b8608332631 257 SUPERFAMILY SSF51735 9 256 7.58E-76 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_00695 018758653184a974115b0b8608332631 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 3.1E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00695 018758653184a974115b0b8608332631 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 3.1E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00695 018758653184a974115b0b8608332631 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 3.1E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00695 018758653184a974115b0b8608332631 257 Gene3D G3DSA:3.40.50.720 5 256 1.1E-77 T 14-10-2018 TSH58p_00695 018758653184a974115b0b8608332631 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_00695 018758653184a974115b0b8608332631 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 3.3E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00695 018758653184a974115b0b8608332631 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 3.3E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00695 018758653184a974115b0b8608332631 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 3.3E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00695 018758653184a974115b0b8608332631 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 3.3E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00695 018758653184a974115b0b8608332631 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 3.3E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00695 018758653184a974115b0b8608332631 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 3.3E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00695 018758653184a974115b0b8608332631 257 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 193 0.0091 T 14-10-2018 TSH58p_11370 a9b650db0d746bdba9fde30fbc2fa4c6 389 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 261 269 - T 14-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TSH58p_11370 a9b650db0d746bdba9fde30fbc2fa4c6 389 SUPERFAMILY SSF55973 235 386 7.46E-65 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TSH58p_11370 a9b650db0d746bdba9fde30fbc2fa4c6 389 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 5 104 2.1E-35 T 14-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TSH58p_11370 a9b650db0d746bdba9fde30fbc2fa4c6 389 Gene3D G3DSA:3.30.300.10 13 272 2.2E-162 T 14-10-2018 TSH58p_11370 a9b650db0d746bdba9fde30fbc2fa4c6 389 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 7 387 6.4E-152 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TSH58p_11370 a9b650db0d746bdba9fde30fbc2fa4c6 389 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 235 377 9.6E-65 T 14-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TSH58p_11370 a9b650db0d746bdba9fde30fbc2fa4c6 389 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 119 129 - T 14-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TSH58p_11370 a9b650db0d746bdba9fde30fbc2fa4c6 389 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 4 388 48.614 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TSH58p_11370 a9b650db0d746bdba9fde30fbc2fa4c6 389 SUPERFAMILY SSF55973 5 111 2.55E-36 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TSH58p_11370 a9b650db0d746bdba9fde30fbc2fa4c6 389 Pfam PF02772 S-adenosylmethionine synthetase, central domain 118 233 2.1E-39 T 14-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TSH58p_11370 a9b650db0d746bdba9fde30fbc2fa4c6 389 SUPERFAMILY SSF55973 115 234 7.85E-46 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TSH58p_11370 a9b650db0d746bdba9fde30fbc2fa4c6 389 Gene3D G3DSA:3.30.300.10 105 379 2.2E-162 T 14-10-2018 TSH58p_11370 a9b650db0d746bdba9fde30fbc2fa4c6 389 PIRSF PIRSF000497 1 388 1.1E-158 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TSH58p_11370 a9b650db0d746bdba9fde30fbc2fa4c6 389 Gene3D G3DSA:3.30.300.10 7 235 2.2E-162 T 14-10-2018 TSH58p_13210 1e01ae3839e574403ca958abcae0f0ff 322 Pfam PF02911 Formyl transferase, C-terminal domain 206 305 1.9E-23 T 14-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TSH58p_13210 1e01ae3839e574403ca958abcae0f0ff 322 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 5 309 1.2E-87 T 14-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 TSH58p_13210 1e01ae3839e574403ca958abcae0f0ff 322 Gene3D G3DSA:3.40.50.12230 4 313 1.8E-106 T 14-10-2018 TSH58p_13210 1e01ae3839e574403ca958abcae0f0ff 322 Pfam PF00551 Formyl transferase 5 183 1.0E-47 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TSH58p_13210 1e01ae3839e574403ca958abcae0f0ff 322 SUPERFAMILY SSF53328 1 206 5.36E-68 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TSH58p_13210 1e01ae3839e574403ca958abcae0f0ff 322 SUPERFAMILY SSF50486 207 313 1.05E-27 T 14-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 TSH58p_13210 1e01ae3839e574403ca958abcae0f0ff 322 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 4 308 36.042 T 14-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 TSH58p_13210 1e01ae3839e574403ca958abcae0f0ff 322 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 135 158 - T 14-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TSH58p_20540 2d95ae653bbb5718b78854cdebf430fb 416 Pfam PF02515 CoA-transferase family III 5 392 6.2E-93 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 TSH58p_20540 2d95ae653bbb5718b78854cdebf430fb 416 Gene3D G3DSA:3.30.1540.10 243 339 2.1E-155 T 14-10-2018 TSH58p_20540 2d95ae653bbb5718b78854cdebf430fb 416 SUPERFAMILY SSF89796 1 416 2.09E-122 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily TSH58p_20540 2d95ae653bbb5718b78854cdebf430fb 416 TIGRFAM TIGR03253 oxalate_frc: formyl-CoA transferase 3 416 5.2E-219 T 14-10-2018 IPR017659 Formyl-CoA:oxalate CoA-transferase GO:0033608 MetaCyc: PWY-6695 TSH58p_20540 2d95ae653bbb5718b78854cdebf430fb 416 Hamap MF_00742 Formyl-CoA:oxalate CoA-transferase [frc]. 1 416 63.309 T 14-10-2018 IPR017659 Formyl-CoA:oxalate CoA-transferase GO:0033608 MetaCyc: PWY-6695 TSH58p_20540 2d95ae653bbb5718b78854cdebf430fb 416 Gene3D G3DSA:3.40.50.10540 4 408 2.1E-155 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily TSH58p_07950 55b53076d4ffc09ca439e9434d5d31c1 334 Gene3D G3DSA:2.130.10.10 28 203 9.7E-61 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TSH58p_07950 55b53076d4ffc09ca439e9434d5d31c1 334 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 226 240 - T 14-10-2018 IPR019775 WD40 repeat, conserved site TSH58p_07950 55b53076d4ffc09ca439e9434d5d31c1 334 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 58 72 - T 14-10-2018 IPR019775 WD40 repeat, conserved site TSH58p_07950 55b53076d4ffc09ca439e9434d5d31c1 334 SUPERFAMILY SSF50978 38 324 2.01E-96 T 14-10-2018 IPR036322 WD40-repeat-containing domain superfamily GO:0005515 TSH58p_07950 55b53076d4ffc09ca439e9434d5d31c1 334 Pfam PF00400 WD domain, G-beta repeat 244 282 8.7E-9 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 TSH58p_07950 55b53076d4ffc09ca439e9434d5d31c1 334 Pfam PF00400 WD domain, G-beta repeat 118 155 5.9E-6 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 TSH58p_07950 55b53076d4ffc09ca439e9434d5d31c1 334 Pfam PF00400 WD domain, G-beta repeat 202 239 7.0E-7 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 TSH58p_07950 55b53076d4ffc09ca439e9434d5d31c1 334 Pfam PF00400 WD domain, G-beta repeat 39 71 1.9E-5 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 TSH58p_07950 55b53076d4ffc09ca439e9434d5d31c1 334 Pfam PF00400 WD domain, G-beta repeat 79 113 1.6E-4 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 TSH58p_07950 55b53076d4ffc09ca439e9434d5d31c1 334 Pfam PF00400 WD domain, G-beta repeat 159 197 7.0E-8 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 TSH58p_07950 55b53076d4ffc09ca439e9434d5d31c1 334 Pfam PF00400 WD domain, G-beta repeat 287 324 9.4E-6 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 TSH58p_07950 55b53076d4ffc09ca439e9434d5d31c1 334 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 100 114 - T 14-10-2018 IPR019775 WD40 repeat, conserved site TSH58p_07950 55b53076d4ffc09ca439e9434d5d31c1 334 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 184 198 - T 14-10-2018 IPR019775 WD40 repeat, conserved site TSH58p_07950 55b53076d4ffc09ca439e9434d5d31c1 334 PRINTS PR00320 G protein beta WD-40 repeat signature 269 283 1.1E-6 T 14-10-2018 IPR020472 G-protein beta WD-40 repeat TSH58p_07950 55b53076d4ffc09ca439e9434d5d31c1 334 PRINTS PR00320 G protein beta WD-40 repeat signature 100 114 1.1E-6 T 14-10-2018 IPR020472 G-protein beta WD-40 repeat TSH58p_07950 55b53076d4ffc09ca439e9434d5d31c1 334 PRINTS PR00320 G protein beta WD-40 repeat signature 226 240 1.1E-6 T 14-10-2018 IPR020472 G-protein beta WD-40 repeat TSH58p_07950 55b53076d4ffc09ca439e9434d5d31c1 334 SMART SM00320 32 71 4.0E-5 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 TSH58p_07950 55b53076d4ffc09ca439e9434d5d31c1 334 SMART SM00320 116 155 2.7E-7 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 TSH58p_07950 55b53076d4ffc09ca439e9434d5d31c1 334 SMART SM00320 74 113 2.2E-7 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 TSH58p_07950 55b53076d4ffc09ca439e9434d5d31c1 334 SMART SM00320 242 282 1.7E-9 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 TSH58p_07950 55b53076d4ffc09ca439e9434d5d31c1 334 SMART SM00320 158 197 9.6E-11 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 TSH58p_07950 55b53076d4ffc09ca439e9434d5d31c1 334 SMART SM00320 285 324 1.6E-8 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 TSH58p_07950 55b53076d4ffc09ca439e9434d5d31c1 334 SMART SM00320 200 239 2.0E-10 T 14-10-2018 IPR001680 WD40 repeat GO:0005515 TSH58p_07950 55b53076d4ffc09ca439e9434d5d31c1 334 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 269 283 - T 14-10-2018 IPR019775 WD40 repeat, conserved site TSH58p_07950 55b53076d4ffc09ca439e9434d5d31c1 334 Gene3D G3DSA:2.130.10.10 274 333 2.9E-17 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TSH58p_07950 55b53076d4ffc09ca439e9434d5d31c1 334 Gene3D G3DSA:2.130.10.10 204 273 1.1E-26 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TSH58p_12795 fe40d9e679133e10dfa4819b65243de5 216 Pfam PF14681 Uracil phosphoribosyltransferase 12 215 2.3E-67 T 14-10-2018 TSH58p_12795 fe40d9e679133e10dfa4819b65243de5 216 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 11 216 7.0E-75 T 14-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 TSH58p_12795 fe40d9e679133e10dfa4819b65243de5 216 SUPERFAMILY SSF53271 10 214 1.35E-60 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like TSH58p_12795 fe40d9e679133e10dfa4819b65243de5 216 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 9 216 41.848 T 14-10-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 TSH58p_12795 fe40d9e679133e10dfa4819b65243de5 216 Gene3D G3DSA:3.40.50.2020 1 216 3.5E-74 T 14-10-2018 TSH58p_04485 0f49f799c84155138022f802dd682aec 463 SUPERFAMILY SSF56954 9 431 2.62E-77 T 14-10-2018 TSH58p_04485 0f49f799c84155138022f802dd682aec 463 Pfam PF02321 Outer membrane efflux protein 34 222 2.1E-27 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 TSH58p_04485 0f49f799c84155138022f802dd682aec 463 Pfam PF02321 Outer membrane efflux protein 241 415 9.0E-27 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 TSH58p_04485 0f49f799c84155138022f802dd682aec 463 Gene3D G3DSA:1.20.1600.10 32 444 1.9E-91 T 14-10-2018 TSH58p_04485 0f49f799c84155138022f802dd682aec 463 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 31 444 6.0E-97 T 14-10-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0015562|GO:0019867|GO:0055085 TSH58p_25465 79c6a5ae59086ea0635ef23fc698657e 486 SUPERFAMILY SSF53041 11 79 4.32E-7 T 14-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 TSH58p_25465 79c6a5ae59086ea0635ef23fc698657e 486 Pfam PF07508 Recombinase 106 217 3.7E-18 T 14-10-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 TSH58p_25465 79c6a5ae59086ea0635ef23fc698657e 486 Gene3D G3DSA:1.10.10.2600 64 221 3.0E-12 T 14-10-2018 IPR038109 DNA-binding recombinase domain superfamily TSH58p_25465 79c6a5ae59086ea0635ef23fc698657e 486 Pfam PF13408 Recombinase zinc beta ribbon domain 243 294 4.0E-9 T 14-10-2018 IPR025827 Recombinase zinc beta ribbon domain TSH58p_12700 22063bd4e5335c66bc143ba1cc4eb2d2 656 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 279 314 - T 14-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 TSH58p_12700 22063bd4e5335c66bc143ba1cc4eb2d2 656 SUPERFAMILY SSF53850 457 650 5.15E-12 T 14-10-2018 TSH58p_12700 22063bd4e5335c66bc143ba1cc4eb2d2 656 Pfam PF00994 Probable molybdopterin binding domain 207 344 2.2E-23 T 14-10-2018 IPR001453 MoaB/Mog domain TSH58p_12700 22063bd4e5335c66bc143ba1cc4eb2d2 656 Gene3D G3DSA:2.40.340.10 355 429 2.9E-15 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_12700 22063bd4e5335c66bc143ba1cc4eb2d2 656 Gene3D G3DSA:3.40.980.10 202 344 5.5E-98 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSH58p_12700 22063bd4e5335c66bc143ba1cc4eb2d2 656 Gene3D G3DSA:3.90.105.10 44 201 5.5E-98 T 14-10-2018 TSH58p_12700 22063bd4e5335c66bc143ba1cc4eb2d2 656 SUPERFAMILY SSF63882 25 203 1.26E-46 T 14-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_12700 22063bd4e5335c66bc143ba1cc4eb2d2 656 Gene3D G3DSA:2.170.190.11 67 168 5.5E-98 T 14-10-2018 TSH58p_12700 22063bd4e5335c66bc143ba1cc4eb2d2 656 SUPERFAMILY SSF63867 356 429 1.23E-13 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_12700 22063bd4e5335c66bc143ba1cc4eb2d2 656 Pfam PF03454 MoeA C-terminal region (domain IV) 363 427 9.3E-13 T 14-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_12700 22063bd4e5335c66bc143ba1cc4eb2d2 656 Pfam PF12727 PBP superfamily domain 459 636 9.5E-54 T 14-10-2018 IPR024370 PBP domain TSH58p_12700 22063bd4e5335c66bc143ba1cc4eb2d2 656 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 204 341 6.1E-26 T 14-10-2018 IPR001453 MoaB/Mog domain TSH58p_12700 22063bd4e5335c66bc143ba1cc4eb2d2 656 SMART SM00852 207 345 3.9E-34 T 14-10-2018 IPR001453 MoaB/Mog domain TSH58p_12700 22063bd4e5335c66bc143ba1cc4eb2d2 656 Pfam PF03453 MoeA N-terminal region (domain I and II) 26 194 2.4E-40 T 14-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_12700 22063bd4e5335c66bc143ba1cc4eb2d2 656 SUPERFAMILY SSF53218 204 350 4.58E-36 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSH58p_22465 9e81c53814bff6578228cd49206b948d 193 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 2 79 9.3E-23 T 14-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 TSH58p_22465 9e81c53814bff6578228cd49206b948d 193 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 2.6E-13 T 14-10-2018 TSH58p_22465 9e81c53814bff6578228cd49206b948d 193 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 2.6E-13 T 14-10-2018 TSH58p_22465 9e81c53814bff6578228cd49206b948d 193 Pfam PF02416 mttA/Hcf106 family 5 37 8.6E-5 T 14-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 TSH58p_22465 9e81c53814bff6578228cd49206b948d 193 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 1 148 15.662 T 14-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 TSH58p_29205 b43f7f92a27493f66f9b143e675c9be6 272 SUPERFAMILY SSF53474 8 268 1.34E-51 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_29205 b43f7f92a27493f66f9b143e675c9be6 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 215 229 1.9E-14 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_29205 b43f7f92a27493f66f9b143e675c9be6 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 1.9E-14 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_29205 b43f7f92a27493f66f9b143e675c9be6 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 114 127 1.9E-14 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_29205 b43f7f92a27493f66f9b143e675c9be6 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 56 71 1.9E-14 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_29205 b43f7f92a27493f66f9b143e675c9be6 272 Pfam PF12697 Alpha/beta hydrolase family 34 257 9.9E-22 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_29205 b43f7f92a27493f66f9b143e675c9be6 272 Gene3D G3DSA:3.40.50.1820 2 270 5.8E-55 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_03985 1c42e93d8f0f9a394cee6e6c5cc270c0 466 Pfam PF13541 Subunit ChlI of Mg-chelatase 336 424 1.5E-7 T 14-10-2018 TSH58p_03985 1c42e93d8f0f9a394cee6e6c5cc270c0 466 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 448 2.1E-168 T 14-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 TSH58p_03985 1c42e93d8f0f9a394cee6e6c5cc270c0 466 Gene3D G3DSA:3.40.50.300 68 275 4.5E-38 T 14-10-2018 TSH58p_03985 1c42e93d8f0f9a394cee6e6c5cc270c0 466 Gene3D G3DSA:3.30.230.10 284 455 1.6E-16 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSH58p_03985 1c42e93d8f0f9a394cee6e6c5cc270c0 466 SUPERFAMILY SSF54211 251 429 1.74E-37 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSH58p_03985 1c42e93d8f0f9a394cee6e6c5cc270c0 466 SMART SM00382 86 240 4.3E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_03985 1c42e93d8f0f9a394cee6e6c5cc270c0 466 SUPERFAMILY SSF52540 67 288 3.63E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_03985 1c42e93d8f0f9a394cee6e6c5cc270c0 466 PRINTS PR01874 DNA repair protein radA signature 209 237 4.4E-89 T 14-10-2018 TSH58p_03985 1c42e93d8f0f9a394cee6e6c5cc270c0 466 PRINTS PR01874 DNA repair protein radA signature 170 194 4.4E-89 T 14-10-2018 TSH58p_03985 1c42e93d8f0f9a394cee6e6c5cc270c0 466 PRINTS PR01874 DNA repair protein radA signature 318 341 4.4E-89 T 14-10-2018 TSH58p_03985 1c42e93d8f0f9a394cee6e6c5cc270c0 466 PRINTS PR01874 DNA repair protein radA signature 10 34 4.4E-89 T 14-10-2018 TSH58p_03985 1c42e93d8f0f9a394cee6e6c5cc270c0 466 PRINTS PR01874 DNA repair protein radA signature 119 136 4.4E-89 T 14-10-2018 TSH58p_03985 1c42e93d8f0f9a394cee6e6c5cc270c0 466 PRINTS PR01874 DNA repair protein radA signature 244 270 4.4E-89 T 14-10-2018 TSH58p_03985 1c42e93d8f0f9a394cee6e6c5cc270c0 466 PRINTS PR01874 DNA repair protein radA signature 78 106 4.4E-89 T 14-10-2018 TSH58p_03985 1c42e93d8f0f9a394cee6e6c5cc270c0 466 Hamap MF_01498 DNA repair protein RadA [radA]. 21 454 43.041 T 14-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 TSH58p_03985 1c42e93d8f0f9a394cee6e6c5cc270c0 466 Pfam PF13481 AAA domain 72 218 2.7E-14 T 14-10-2018 TSH58p_31945 bfa4903a5542df8dd5ffdf6de6520076 260 SUPERFAMILY SSF48008 116 251 1.96E-26 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_31945 bfa4903a5542df8dd5ffdf6de6520076 260 SMART SM00345 36 95 4.5E-22 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_31945 bfa4903a5542df8dd5ffdf6de6520076 260 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 69 85 2.7E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_31945 bfa4903a5542df8dd5ffdf6de6520076 260 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 55 69 2.7E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_31945 bfa4903a5542df8dd5ffdf6de6520076 260 SMART SM00895 119 245 8.3E-19 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_31945 bfa4903a5542df8dd5ffdf6de6520076 260 SUPERFAMILY SSF46785 27 98 1.4E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_31945 bfa4903a5542df8dd5ffdf6de6520076 260 Gene3D G3DSA:1.20.120.530 113 254 7.6E-28 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_31945 bfa4903a5542df8dd5ffdf6de6520076 260 Pfam PF07729 FCD domain 121 244 8.4E-23 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_31945 bfa4903a5542df8dd5ffdf6de6520076 260 Pfam PF00392 Bacterial regulatory proteins, gntR family 33 95 5.1E-21 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_31945 bfa4903a5542df8dd5ffdf6de6520076 260 Gene3D G3DSA:1.10.10.10 23 102 4.0E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_10400 677c914f4495465c6c0d88fcc01fbab4 178 Pfam PF02834 LigT like Phosphoesterase 92 167 1.9E-13 T 14-10-2018 IPR014051 Phosphoesterase, HXTX TSH58p_10400 677c914f4495465c6c0d88fcc01fbab4 178 Pfam PF02834 LigT like Phosphoesterase 9 86 2.4E-16 T 14-10-2018 IPR014051 Phosphoesterase, HXTX TSH58p_10400 677c914f4495465c6c0d88fcc01fbab4 178 Gene3D G3DSA:3.90.1140.10 2 178 9.7E-49 T 14-10-2018 TSH58p_10400 677c914f4495465c6c0d88fcc01fbab4 178 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 2 177 26.974 T 14-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 TSH58p_10400 677c914f4495465c6c0d88fcc01fbab4 178 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 2 175 1.1E-50 T 14-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 TSH58p_10400 677c914f4495465c6c0d88fcc01fbab4 178 SUPERFAMILY SSF55144 2 177 1.15E-46 T 14-10-2018 IPR009097 Cyclic phosphodiesterase TSH58p_32450 df5ef80ae65eebedd4e9bcdb396e6fbd 259 SUPERFAMILY SSF51735 3 258 6.81E-80 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_32450 df5ef80ae65eebedd4e9bcdb396e6fbd 259 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 4 258 9.5E-101 T 14-10-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 TSH58p_32450 df5ef80ae65eebedd4e9bcdb396e6fbd 259 Gene3D G3DSA:3.40.50.720 1 259 1.4E-85 T 14-10-2018 TSH58p_32450 df5ef80ae65eebedd4e9bcdb396e6fbd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 4.7E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_32450 df5ef80ae65eebedd4e9bcdb396e6fbd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 4.7E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_32450 df5ef80ae65eebedd4e9bcdb396e6fbd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.7E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_32450 df5ef80ae65eebedd4e9bcdb396e6fbd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 4.7E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_32450 df5ef80ae65eebedd4e9bcdb396e6fbd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 4.7E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_32450 df5ef80ae65eebedd4e9bcdb396e6fbd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.7E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_32450 df5ef80ae65eebedd4e9bcdb396e6fbd 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_32450 df5ef80ae65eebedd4e9bcdb396e6fbd 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 8.8E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_32450 df5ef80ae65eebedd4e9bcdb396e6fbd 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 8.8E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_32450 df5ef80ae65eebedd4e9bcdb396e6fbd 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 8.8E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_32450 df5ef80ae65eebedd4e9bcdb396e6fbd 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 257 2.1E-61 T 14-10-2018 TSH58p_15895 f9f32b7bf0e3d7efc301921232a0fdd6 282 PIRSF PIRSF000094 5 263 1.7E-112 T 14-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 TSH58p_15895 f9f32b7bf0e3d7efc301921232a0fdd6 282 Gene3D G3DSA:1.10.8.400 206 261 9.9E-16 T 14-10-2018 TSH58p_15895 f9f32b7bf0e3d7efc301921232a0fdd6 282 SUPERFAMILY SSF51735 9 258 7.78E-70 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_15895 f9f32b7bf0e3d7efc301921232a0fdd6 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 2.5E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_15895 f9f32b7bf0e3d7efc301921232a0fdd6 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 2.5E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_15895 f9f32b7bf0e3d7efc301921232a0fdd6 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 2.5E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_15895 f9f32b7bf0e3d7efc301921232a0fdd6 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 2.5E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_15895 f9f32b7bf0e3d7efc301921232a0fdd6 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 2.5E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_15895 f9f32b7bf0e3d7efc301921232a0fdd6 282 Gene3D G3DSA:3.40.50.720 12 204 3.0E-43 T 14-10-2018 TSH58p_15895 f9f32b7bf0e3d7efc301921232a0fdd6 282 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 255 7.6E-91 T 14-10-2018 TSH58p_22450 72815d670d969364d8a10fb43c4fa6dc 421 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 221 396 2.2E-35 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_22450 72815d670d969364d8a10fb43c4fa6dc 421 PIRSF PIRSF001529 1 421 8.2E-169 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TSH58p_22450 72815d670d969364d8a10fb43c4fa6dc 421 Gene3D G3DSA:3.30.930.10 105 421 1.2E-121 T 14-10-2018 TSH58p_22450 72815d670d969364d8a10fb43c4fa6dc 421 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 413 5.6E-159 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TSH58p_22450 72815d670d969364d8a10fb43c4fa6dc 421 PRINTS PR00981 Seryl-tRNA synthetase signature 312 325 1.2E-33 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TSH58p_22450 72815d670d969364d8a10fb43c4fa6dc 421 PRINTS PR00981 Seryl-tRNA synthetase signature 272 285 1.2E-33 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TSH58p_22450 72815d670d969364d8a10fb43c4fa6dc 421 PRINTS PR00981 Seryl-tRNA synthetase signature 329 345 1.2E-33 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TSH58p_22450 72815d670d969364d8a10fb43c4fa6dc 421 PRINTS PR00981 Seryl-tRNA synthetase signature 347 363 1.2E-33 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TSH58p_22450 72815d670d969364d8a10fb43c4fa6dc 421 PRINTS PR00981 Seryl-tRNA synthetase signature 260 272 1.2E-33 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TSH58p_22450 72815d670d969364d8a10fb43c4fa6dc 421 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 418 40.801 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TSH58p_22450 72815d670d969364d8a10fb43c4fa6dc 421 SUPERFAMILY SSF46589 1 112 4.29E-30 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 TSH58p_22450 72815d670d969364d8a10fb43c4fa6dc 421 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 9.1E-29 T 14-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 TSH58p_22450 72815d670d969364d8a10fb43c4fa6dc 421 Gene3D G3DSA:1.10.287.40 1 104 1.9E-24 T 14-10-2018 TSH58p_22450 72815d670d969364d8a10fb43c4fa6dc 421 SUPERFAMILY SSF55681 116 414 6.49E-95 T 14-10-2018 TSH58p_30675 aac41f499e96787e1bc3091f464eb14f 282 SUPERFAMILY SSF161098 9 258 1.96E-52 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_30675 aac41f499e96787e1bc3091f464eb14f 282 Gene3D G3DSA:1.10.3720.10 8 264 1.3E-51 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_30675 aac41f499e96787e1bc3091f464eb14f 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 251 5.7E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_09640 cb7573b2d9772ec5eb3a554ddaa454b0 392 Gene3D G3DSA:3.60.40.10 136 389 8.5E-35 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSH58p_09640 cb7573b2d9772ec5eb3a554ddaa454b0 392 Gene3D G3DSA:3.40.50.2300 4 135 3.3E-37 T 14-10-2018 TSH58p_09640 cb7573b2d9772ec5eb3a554ddaa454b0 392 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 196 386 8.0E-22 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSH58p_09640 cb7573b2d9772ec5eb3a554ddaa454b0 392 SMART SM00331 169 388 0.0014 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSH58p_09640 cb7573b2d9772ec5eb3a554ddaa454b0 392 SUPERFAMILY SSF52172 8 153 2.7E-40 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_09640 cb7573b2d9772ec5eb3a554ddaa454b0 392 SMART SM00448 8 122 3.0E-36 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_09640 cb7573b2d9772ec5eb3a554ddaa454b0 392 Pfam PF00072 Response regulator receiver domain 10 123 3.5E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_15700 ff82d8e62625bfd82496d326dceea50b 391 SUPERFAMILY SSF52317 167 387 8.87E-62 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_15700 ff82d8e62625bfd82496d326dceea50b 391 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 16 143 7.5E-50 T 14-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSH58p_15700 ff82d8e62625bfd82496d326dceea50b 391 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 17 386 1.6E-139 T 14-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSH58p_15700 ff82d8e62625bfd82496d326dceea50b 391 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 14 389 48.811 T 14-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSH58p_15700 ff82d8e62625bfd82496d326dceea50b 391 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 204 218 2.3E-37 T 14-10-2018 TSH58p_15700 ff82d8e62625bfd82496d326dceea50b 391 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 243 257 2.3E-37 T 14-10-2018 TSH58p_15700 ff82d8e62625bfd82496d326dceea50b 391 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 275 291 2.3E-37 T 14-10-2018 TSH58p_15700 ff82d8e62625bfd82496d326dceea50b 391 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 292 309 2.3E-37 T 14-10-2018 TSH58p_15700 ff82d8e62625bfd82496d326dceea50b 391 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 317 328 2.3E-37 T 14-10-2018 TSH58p_15700 ff82d8e62625bfd82496d326dceea50b 391 PRINTS PR00097 Anthranilate synthase component II signature 360 373 1.2E-6 T 14-10-2018 TSH58p_15700 ff82d8e62625bfd82496d326dceea50b 391 PRINTS PR00097 Anthranilate synthase component II signature 275 286 1.2E-6 T 14-10-2018 TSH58p_15700 ff82d8e62625bfd82496d326dceea50b 391 PRINTS PR00097 Anthranilate synthase component II signature 246 255 1.2E-6 T 14-10-2018 TSH58p_15700 ff82d8e62625bfd82496d326dceea50b 391 SMART SM01097 14 144 3.8E-85 T 14-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSH58p_15700 ff82d8e62625bfd82496d326dceea50b 391 Gene3D G3DSA:3.40.50.880 165 387 1.3E-74 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_15700 ff82d8e62625bfd82496d326dceea50b 391 Pfam PF00117 Glutamine amidotransferase class-I 206 383 8.3E-47 T 14-10-2018 IPR017926 Glutamine amidotransferase TSH58p_15700 ff82d8e62625bfd82496d326dceea50b 391 PRINTS PR00096 Glutamine amidotransferase superfamily signature 246 255 3.0E-12 T 14-10-2018 TSH58p_15700 ff82d8e62625bfd82496d326dceea50b 391 PRINTS PR00096 Glutamine amidotransferase superfamily signature 360 373 3.0E-12 T 14-10-2018 TSH58p_15700 ff82d8e62625bfd82496d326dceea50b 391 PRINTS PR00096 Glutamine amidotransferase superfamily signature 275 286 3.0E-12 T 14-10-2018 TSH58p_15700 ff82d8e62625bfd82496d326dceea50b 391 Gene3D G3DSA:3.50.30.20 14 163 1.2E-52 T 14-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSH58p_15700 ff82d8e62625bfd82496d326dceea50b 391 SUPERFAMILY SSF52021 15 159 2.35E-54 T 14-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSH58p_26730 29d2b96a9f5f9fb480ae942fe86704e0 688 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 463 591 2.1E-35 T 14-10-2018 IPR025299 CstA, C-terminal domain TSH58p_26730 29d2b96a9f5f9fb480ae942fe86704e0 688 Pfam PF02554 Carbon starvation protein CstA 32 409 2.3E-168 T 14-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 TSH58p_02500 9b17db4a83f4ccc6cb97b5bcb4497d85 6445 SMART SM00912 80 193 2.6E-43 T 14-10-2018 IPR008638 Filamentous haemagglutinin, N-terminal TSH58p_02500 9b17db4a83f4ccc6cb97b5bcb4497d85 6445 Gene3D G3DSA:2.160.20.10 83 464 4.1E-95 T 14-10-2018 IPR012334 Pectin lyase fold TSH58p_02500 9b17db4a83f4ccc6cb97b5bcb4497d85 6445 SUPERFAMILY SSF51126 98 386 1.54E-36 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor TSH58p_02500 9b17db4a83f4ccc6cb97b5bcb4497d85 6445 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 115 190 1.5E-24 T 14-10-2018 IPR008638 Filamentous haemagglutinin, N-terminal TSH58p_15220 d3375ea70ee727265d6d6140d8145be1 106 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 41 104 2.5E-29 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_15220 d3375ea70ee727265d6d6140d8145be1 106 Pfam PF00467 KOW motif 10 38 2.8E-7 T 14-10-2018 IPR005824 KOW TSH58p_15220 d3375ea70ee727265d6d6140d8145be1 106 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 4 98 21.749 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_15220 d3375ea70ee727265d6d6140d8145be1 106 Gene3D G3DSA:2.30.30.30 3 105 4.0E-40 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 TSH58p_15220 d3375ea70ee727265d6d6140d8145be1 106 SMART SM00739 5 32 1.3E-4 T 14-10-2018 IPR005824 KOW TSH58p_15220 d3375ea70ee727265d6d6140d8145be1 106 SUPERFAMILY SSF50104 4 103 1.39E-35 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily TSH58p_15220 d3375ea70ee727265d6d6140d8145be1 106 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 4 104 5.3E-39 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_02190 a9dfaf2ae6ec0d5367ef58d876ebc53d 640 Pfam PF13844 Glycosyl transferase family 41 431 621 1.4E-43 T 14-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 TSH58p_02190 a9dfaf2ae6ec0d5367ef58d876ebc53d 640 Pfam PF13844 Glycosyl transferase family 41 271 421 3.4E-40 T 14-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 TSH58p_02190 a9dfaf2ae6ec0d5367ef58d876ebc53d 640 Gene3D G3DSA:1.25.40.10 125 226 5.2E-21 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_02190 a9dfaf2ae6ec0d5367ef58d876ebc53d 640 SUPERFAMILY SSF48452 21 193 2.36E-29 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_02190 a9dfaf2ae6ec0d5367ef58d876ebc53d 640 Gene3D G3DSA:3.40.50.11380 262 612 1.1E-134 T 14-10-2018 TSH58p_02190 a9dfaf2ae6ec0d5367ef58d876ebc53d 640 SMART SM00028 157 190 0.0033 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_02190 a9dfaf2ae6ec0d5367ef58d876ebc53d 640 SMART SM00028 123 156 17.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_02190 a9dfaf2ae6ec0d5367ef58d876ebc53d 640 SMART SM00028 55 88 0.32 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_02190 a9dfaf2ae6ec0d5367ef58d876ebc53d 640 SMART SM00028 89 122 0.11 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_02190 a9dfaf2ae6ec0d5367ef58d876ebc53d 640 Pfam PF13432 Tetratricopeptide repeat 93 157 4.8E-9 T 14-10-2018 TSH58p_02190 a9dfaf2ae6ec0d5367ef58d876ebc53d 640 Pfam PF13432 Tetratricopeptide repeat 21 89 1.4E-5 T 14-10-2018 TSH58p_02190 a9dfaf2ae6ec0d5367ef58d876ebc53d 640 Gene3D G3DSA:1.25.40.10 20 124 1.0E-17 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_02190 a9dfaf2ae6ec0d5367ef58d876ebc53d 640 Gene3D G3DSA:3.40.50.2000 427 606 1.1E-134 T 14-10-2018 TSH58p_02190 a9dfaf2ae6ec0d5367ef58d876ebc53d 640 Pfam PF13181 Tetratricopeptide repeat 159 189 0.025 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_18345 528825b25a5f31b9eebb122ebb67c436 191 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 1 190 37.964 T 14-10-2018 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 TSH58p_18345 528825b25a5f31b9eebb122ebb67c436 191 TIGRFAM TIGR00441 gmhA: phosphoheptose isomerase 36 187 8.7E-66 T 14-10-2018 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 TSH58p_18345 528825b25a5f31b9eebb122ebb67c436 191 Gene3D G3DSA:3.40.50.10490 4 190 9.1E-76 T 14-10-2018 TSH58p_18345 528825b25a5f31b9eebb122ebb67c436 191 SUPERFAMILY SSF53697 11 188 8.26E-55 T 14-10-2018 TSH58p_18345 528825b25a5f31b9eebb122ebb67c436 191 Pfam PF13580 SIS domain 24 147 3.4E-32 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TSH58p_20925 a33cb3967c46af279bd2cb9806a1fde7 468 SUPERFAMILY SSF103378 9 454 9.55E-112 T 14-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 TSH58p_20925 a33cb3967c46af279bd2cb9806a1fde7 468 Gene3D G3DSA:3.30.1330.120 279 412 3.6E-107 T 14-10-2018 TSH58p_20925 a33cb3967c46af279bd2cb9806a1fde7 468 Pfam PF03972 MmgE/PrpD family 14 450 1.1E-116 T 14-10-2018 IPR005656 MmgE/PrpD GO:0016829 TSH58p_20925 a33cb3967c46af279bd2cb9806a1fde7 468 Gene3D G3DSA:1.10.4100.10 32 428 3.6E-107 T 14-10-2018 TSH58p_13140 91340effb4c82549831f0500de4e55e7 454 SUPERFAMILY SSF141571 286 445 1.08E-36 T 14-10-2018 TSH58p_13140 91340effb4c82549831f0500de4e55e7 454 Gene3D G3DSA:2.160.20.80 267 372 4.9E-19 T 14-10-2018 TSH58p_13140 91340effb4c82549831f0500de4e55e7 454 SUPERFAMILY SSF141571 151 255 5.49E-25 T 14-10-2018 TSH58p_13140 91340effb4c82549831f0500de4e55e7 454 SUPERFAMILY SSF141571 39 131 3.53E-22 T 14-10-2018 TSH58p_13140 91340effb4c82549831f0500de4e55e7 454 Pfam PF00805 Pentapeptide repeats (8 copies) 86 125 1.0E-9 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_13140 91340effb4c82549831f0500de4e55e7 454 Pfam PF00805 Pentapeptide repeats (8 copies) 40 74 7.8E-6 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_13140 91340effb4c82549831f0500de4e55e7 454 Pfam PF00805 Pentapeptide repeats (8 copies) 415 445 9.8E-9 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_13140 91340effb4c82549831f0500de4e55e7 454 Pfam PF00805 Pentapeptide repeats (8 copies) 185 223 8.3E-14 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_13140 91340effb4c82549831f0500de4e55e7 454 Pfam PF00805 Pentapeptide repeats (8 copies) 379 414 1.3E-9 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_13140 91340effb4c82549831f0500de4e55e7 454 Pfam PF00805 Pentapeptide repeats (8 copies) 333 365 3.1E-9 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_13140 91340effb4c82549831f0500de4e55e7 454 Pfam PF00805 Pentapeptide repeats (8 copies) 228 256 3.3E-4 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_13140 91340effb4c82549831f0500de4e55e7 454 Gene3D G3DSA:2.160.20.80 140 266 1.4E-26 T 14-10-2018 TSH58p_13140 91340effb4c82549831f0500de4e55e7 454 Gene3D G3DSA:2.160.20.100 373 454 2.9E-20 T 14-10-2018 TSH58p_13140 91340effb4c82549831f0500de4e55e7 454 Gene3D G3DSA:2.160.20.80 4 138 8.2E-25 T 14-10-2018 TSH58p_05290 ada67bd0a8d9abc93470aee9c9de3bf5 350 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 8 344 41.445 T 14-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TSH58p_05290 ada67bd0a8d9abc93470aee9c9de3bf5 350 SMART SM00859 9 146 5.6E-54 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TSH58p_05290 ada67bd0a8d9abc93470aee9c9de3bf5 350 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 9 145 1.2E-28 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TSH58p_05290 ada67bd0a8d9abc93470aee9c9de3bf5 350 SUPERFAMILY SSF55347 154 318 1.43E-53 T 14-10-2018 TSH58p_05290 ada67bd0a8d9abc93470aee9c9de3bf5 350 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 8 350 1.1E-129 T 14-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TSH58p_05290 ada67bd0a8d9abc93470aee9c9de3bf5 350 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 149 165 - T 14-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TSH58p_05290 ada67bd0a8d9abc93470aee9c9de3bf5 350 SUPERFAMILY SSF51735 6 170 3.52E-53 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_05290 ada67bd0a8d9abc93470aee9c9de3bf5 350 Gene3D G3DSA:3.30.360.10 152 318 1.2E-135 T 14-10-2018 TSH58p_05290 ada67bd0a8d9abc93470aee9c9de3bf5 350 Gene3D G3DSA:3.40.50.720 9 336 1.2E-135 T 14-10-2018 TSH58p_05290 ada67bd0a8d9abc93470aee9c9de3bf5 350 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 167 321 1.3E-18 T 14-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TSH58p_04165 7fd53a1db8241218346bd545eb3cee7f 505 Pfam PF02872 5'-nucleotidase, C-terminal domain 310 466 2.0E-48 T 14-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSH58p_04165 7fd53a1db8241218346bd545eb3cee7f 505 Pfam PF00149 Calcineurin-like phosphoesterase 31 233 5.8E-8 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TSH58p_04165 7fd53a1db8241218346bd545eb3cee7f 505 Gene3D G3DSA:3.60.21.10 29 307 1.5E-61 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like TSH58p_04165 7fd53a1db8241218346bd545eb3cee7f 505 SUPERFAMILY SSF56300 30 304 1.9E-65 T 14-10-2018 TSH58p_04165 7fd53a1db8241218346bd545eb3cee7f 505 SUPERFAMILY SSF55816 310 503 3.66E-59 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSH58p_04165 7fd53a1db8241218346bd545eb3cee7f 505 Gene3D G3DSA:3.90.780.10 310 505 1.5E-65 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSH58p_04165 7fd53a1db8241218346bd545eb3cee7f 505 PRINTS PR01607 Apyrase family signature 440 459 3.3E-28 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSH58p_04165 7fd53a1db8241218346bd545eb3cee7f 505 PRINTS PR01607 Apyrase family signature 367 390 3.3E-28 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSH58p_04165 7fd53a1db8241218346bd545eb3cee7f 505 PRINTS PR01607 Apyrase family signature 196 213 3.3E-28 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSH58p_04165 7fd53a1db8241218346bd545eb3cee7f 505 PRINTS PR01607 Apyrase family signature 241 261 3.3E-28 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSH58p_04165 7fd53a1db8241218346bd545eb3cee7f 505 PRINTS PR01607 Apyrase family signature 215 238 3.3E-28 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSH58p_05095 9370094f0ef30493f037fb4cc27474b0 229 Gene3D G3DSA:1.10.10.10 14 82 1.5E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_05095 9370094f0ef30493f037fb4cc27474b0 229 SMART SM00345 21 82 1.1E-11 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_05095 9370094f0ef30493f037fb4cc27474b0 229 Gene3D G3DSA:1.20.120.530 86 226 1.7E-28 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_05095 9370094f0ef30493f037fb4cc27474b0 229 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 82 8.6E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_05095 9370094f0ef30493f037fb4cc27474b0 229 Pfam PF07729 FCD domain 92 213 5.3E-27 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_05095 9370094f0ef30493f037fb4cc27474b0 229 SMART SM00895 92 216 3.8E-18 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_05095 9370094f0ef30493f037fb4cc27474b0 229 SUPERFAMILY SSF46785 13 86 6.57E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_05095 9370094f0ef30493f037fb4cc27474b0 229 SUPERFAMILY SSF48008 89 223 2.09E-25 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_05095 9370094f0ef30493f037fb4cc27474b0 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 2.8E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_05095 9370094f0ef30493f037fb4cc27474b0 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 2.8E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_11095 c6a3fb76814edca33ef2b6eb215aceb7 165 Hamap MF_00821 Protein-export protein SecB [secB]. 1 154 29.4 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 TSH58p_11095 c6a3fb76814edca33ef2b6eb215aceb7 165 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 19 150 1.5E-42 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 TSH58p_11095 c6a3fb76814edca33ef2b6eb215aceb7 165 Gene3D G3DSA:3.10.420.10 1 164 1.7E-56 T 14-10-2018 IPR035958 SecB-like superfamily TSH58p_11095 c6a3fb76814edca33ef2b6eb215aceb7 165 Pfam PF02556 Preprotein translocase subunit SecB 15 151 8.7E-53 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 TSH58p_11095 c6a3fb76814edca33ef2b6eb215aceb7 165 SUPERFAMILY SSF54611 10 150 2.83E-47 T 14-10-2018 IPR035958 SecB-like superfamily TSH58p_11095 c6a3fb76814edca33ef2b6eb215aceb7 165 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 106 128 6.1E-26 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 TSH58p_11095 c6a3fb76814edca33ef2b6eb215aceb7 165 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 132 150 6.1E-26 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 TSH58p_11095 c6a3fb76814edca33ef2b6eb215aceb7 165 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 21 38 6.1E-26 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 TSH58p_11095 c6a3fb76814edca33ef2b6eb215aceb7 165 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 82 102 6.1E-26 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 TSH58p_16155 606455466e09de691751f55125415a3e 124 Pfam PF01597 Glycine cleavage H-protein 4 121 5.2E-42 T 14-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate TSH58p_16155 606455466e09de691751f55125415a3e 124 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 121 8.4E-43 T 14-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 TSH58p_16155 606455466e09de691751f55125415a3e 124 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 43 72 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 TSH58p_16155 606455466e09de691751f55125415a3e 124 Gene3D G3DSA:2.40.50.100 2 123 6.8E-48 T 14-10-2018 TSH58p_16155 606455466e09de691751f55125415a3e 124 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 2 121 37.008 T 14-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 TSH58p_16155 606455466e09de691751f55125415a3e 124 SUPERFAMILY SSF51230 3 121 2.42E-43 T 14-10-2018 IPR011053 Single hybrid motif TSH58p_08620 947fa1c90e2224bdbe41cc32b16e6997 449 Gene3D G3DSA:3.30.930.10 2 350 1.4E-107 T 14-10-2018 TSH58p_08620 947fa1c90e2224bdbe41cc32b16e6997 449 SUPERFAMILY SSF52954 354 447 1.96E-21 T 14-10-2018 TSH58p_08620 947fa1c90e2224bdbe41cc32b16e6997 449 Pfam PF13393 Histidyl-tRNA synthetase 11 337 3.0E-37 T 14-10-2018 TSH58p_08620 947fa1c90e2224bdbe41cc32b16e6997 449 SUPERFAMILY SSF55681 6 350 1.67E-74 T 14-10-2018 TSH58p_08620 947fa1c90e2224bdbe41cc32b16e6997 449 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 8 435 2.1E-120 T 14-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 TSH58p_08620 947fa1c90e2224bdbe41cc32b16e6997 449 Pfam PF03129 Anticodon binding domain 359 445 1.3E-13 T 14-10-2018 IPR004154 Anticodon-binding TSH58p_08620 947fa1c90e2224bdbe41cc32b16e6997 449 PIRSF PIRSF001549 2 447 9.9E-132 T 14-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 TSH58p_08620 947fa1c90e2224bdbe41cc32b16e6997 449 Gene3D G3DSA:3.40.50.800 353 447 1.2E-24 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily TSH58p_08620 947fa1c90e2224bdbe41cc32b16e6997 449 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 4 445 27.288 T 14-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 TSH58p_06325 381305a092e16f74adbbca35e83a1e2f 218 Pfam PF00834 Ribulose-phosphate 3 epimerase family 5 202 7.5E-85 T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 TSH58p_06325 381305a092e16f74adbbca35e83a1e2f 218 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 5 217 5.5E-89 T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 TSH58p_06325 381305a092e16f74adbbca35e83a1e2f 218 SUPERFAMILY SSF51366 2 216 2.76E-76 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TSH58p_06325 381305a092e16f74adbbca35e83a1e2f 218 PIRSF PIRSF001461 1 218 4.6E-93 T 14-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 TSH58p_06325 381305a092e16f74adbbca35e83a1e2f 218 Gene3D G3DSA:3.20.20.70 1 218 2.6E-84 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_06325 381305a092e16f74adbbca35e83a1e2f 218 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 135 157 - T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 TSH58p_06325 381305a092e16f74adbbca35e83a1e2f 218 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 33 47 - T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 TSH58p_26630 986035963ea2eecba4367f92f330d64c 462 Gene3D G3DSA:1.10.287.470 120 211 6.1E-9 T 14-10-2018 TSH58p_26630 986035963ea2eecba4367f92f330d64c 462 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 56 79 5.8E-43 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_26630 986035963ea2eecba4367f92f330d64c 462 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 383 406 5.8E-43 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_26630 986035963ea2eecba4367f92f330d64c 462 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 426 441 5.8E-43 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_26630 986035963ea2eecba4367f92f330d64c 462 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 326 347 5.8E-43 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_26630 986035963ea2eecba4367f92f330d64c 462 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 98 118 5.8E-43 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_26630 986035963ea2eecba4367f92f330d64c 462 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 359 383 5.8E-43 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_26630 986035963ea2eecba4367f92f330d64c 462 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 441 461 5.8E-43 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_26630 986035963ea2eecba4367f92f330d64c 462 Gene3D G3DSA:2.40.30.170 351 413 9.2E-18 T 14-10-2018 TSH58p_26630 986035963ea2eecba4367f92f330d64c 462 Gene3D G3DSA:2.40.50.100 244 350 9.2E-18 T 14-10-2018 TSH58p_26630 986035963ea2eecba4367f92f330d64c 462 Gene3D G3DSA:2.40.50.100 85 119 6.1E-9 T 14-10-2018 TSH58p_26630 986035963ea2eecba4367f92f330d64c 462 Pfam PF13533 Biotin-lipoyl like 95 130 4.5E-6 T 14-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain TSH58p_26630 986035963ea2eecba4367f92f330d64c 462 Pfam PF13437 HlyD family secretion protein 314 416 4.1E-18 T 14-10-2018 TSH58p_26630 986035963ea2eecba4367f92f330d64c 462 SUPERFAMILY SSF111369 255 379 5.75E-6 T 14-10-2018 TSH58p_26630 986035963ea2eecba4367f92f330d64c 462 Gene3D G3DSA:1.10.287.470 245 313 9.2E-18 T 14-10-2018 TSH58p_26630 986035963ea2eecba4367f92f330d64c 462 SUPERFAMILY SSF111369 95 166 2.88E-5 T 14-10-2018 TSH58p_26630 986035963ea2eecba4367f92f330d64c 462 Gene3D G3DSA:2.40.30.170 74 84 6.1E-9 T 14-10-2018 TSH58p_26630 986035963ea2eecba4367f92f330d64c 462 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 51 462 4.8E-112 T 14-10-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 TSH58p_31445 b059f00ef99be24bd543ee00b1642713 242 Gene3D G3DSA:3.40.50.300 1 240 2.0E-77 T 14-10-2018 TSH58p_31445 b059f00ef99be24bd543ee00b1642713 242 PIRSF PIRSF039085 1 241 1.2E-101 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 TSH58p_31445 b059f00ef99be24bd543ee00b1642713 242 Pfam PF00005 ABC transporter 17 165 1.2E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_31445 b059f00ef99be24bd543ee00b1642713 242 SUPERFAMILY SSF52540 1 234 3.36E-75 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_31445 b059f00ef99be24bd543ee00b1642713 242 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_31445 b059f00ef99be24bd543ee00b1642713 242 SMART SM00382 26 213 2.2E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_29535 a82f04048f2c32cdf81ba2ac98dd4453 200 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 2 198 4.1E-101 T 14-10-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 TSH58p_29535 a82f04048f2c32cdf81ba2ac98dd4453 200 Gene3D G3DSA:3.40.50.360 1 200 1.0E-79 T 14-10-2018 IPR029039 Flavoprotein-like superfamily TSH58p_29535 a82f04048f2c32cdf81ba2ac98dd4453 200 Hamap MF_01017 NAD(P)H dehydrogenase (quinone). 1 200 49.463 T 14-10-2018 IPR037513 NAD(P)H dehydrogenase (quinone), prokaryotic GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 TSH58p_29535 a82f04048f2c32cdf81ba2ac98dd4453 200 SUPERFAMILY SSF52218 1 199 4.46E-63 T 14-10-2018 IPR029039 Flavoprotein-like superfamily TSH58p_29535 a82f04048f2c32cdf81ba2ac98dd4453 200 Pfam PF03358 NADPH-dependent FMN reductase 13 142 1.1E-13 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 TSH58p_28750 52d342b184aad2636f071f688275dd1a 194 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 3 189 3.6E-58 T 14-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 TSH58p_28750 52d342b184aad2636f071f688275dd1a 194 Hamap MF_00146 dCTP deaminase [dcd]. 1 189 33.344 T 14-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 TSH58p_28750 52d342b184aad2636f071f688275dd1a 194 Pfam PF00692 dUTPase 76 177 7.0E-10 T 14-10-2018 IPR029054 dUTPase-like TSH58p_28750 52d342b184aad2636f071f688275dd1a 194 SUPERFAMILY SSF51283 1 189 7.98E-52 T 14-10-2018 IPR036157 dUTPase-like superfamily TSH58p_28750 52d342b184aad2636f071f688275dd1a 194 Gene3D G3DSA:2.70.40.10 1 193 2.2E-52 T 14-10-2018 IPR036157 dUTPase-like superfamily TSH58p_28390 c1162d43b3ede3cc004ea6f42d8a13a5 532 Gene3D G3DSA:2.40.320.10 14 216 1.2E-24 T 14-10-2018 TSH58p_28390 c1162d43b3ede3cc004ea6f42d8a13a5 532 Pfam PF05235 CHAD domain 249 487 8.9E-42 T 14-10-2018 IPR007899 CHAD domain TSH58p_28390 c1162d43b3ede3cc004ea6f42d8a13a5 532 SMART SM01118 16 222 2.0E-18 T 14-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 TSH58p_28390 c1162d43b3ede3cc004ea6f42d8a13a5 532 Pfam PF01928 CYTH domain 17 202 8.3E-17 T 14-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 TSH58p_28390 c1162d43b3ede3cc004ea6f42d8a13a5 532 Gene3D G3DSA:1.40.20.10 230 530 1.2E-59 T 14-10-2018 IPR038186 CHAD domain superfamily TSH58p_28390 c1162d43b3ede3cc004ea6f42d8a13a5 532 SMART SM00880 247 521 1.0E-47 T 14-10-2018 IPR007899 CHAD domain TSH58p_28390 c1162d43b3ede3cc004ea6f42d8a13a5 532 SUPERFAMILY SSF55154 15 235 1.41E-31 T 14-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 TSH58p_29530 981a5b516ee7cc917a4942280840680c 312 Gene3D G3DSA:3.40.190.10 91 290 4.6E-76 T 14-10-2018 TSH58p_29530 981a5b516ee7cc917a4942280840680c 312 Pfam PF03466 LysR substrate binding domain 88 292 3.6E-49 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_29530 981a5b516ee7cc917a4942280840680c 312 Gene3D G3DSA:3.40.190.10 163 264 4.6E-76 T 14-10-2018 TSH58p_29530 981a5b516ee7cc917a4942280840680c 312 SUPERFAMILY SSF53850 90 296 3.8E-52 T 14-10-2018 TSH58p_29530 981a5b516ee7cc917a4942280840680c 312 Gene3D G3DSA:1.10.10.10 3 89 5.1E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_29530 981a5b516ee7cc917a4942280840680c 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.7E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_29530 981a5b516ee7cc917a4942280840680c 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.0E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_29530 981a5b516ee7cc917a4942280840680c 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.0E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_29530 981a5b516ee7cc917a4942280840680c 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.0E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_29530 981a5b516ee7cc917a4942280840680c 312 SUPERFAMILY SSF46785 4 87 4.15E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_11670 cdef6ad5d33fc584d50f62b1a5c8bb0b 501 Pfam PF00512 His Kinase A (phospho-acceptor) domain 244 308 2.0E-18 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_11670 cdef6ad5d33fc584d50f62b1a5c8bb0b 501 SUPERFAMILY SSF55874 299 483 3.8E-46 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_11670 cdef6ad5d33fc584d50f62b1a5c8bb0b 501 SMART SM00388 243 310 1.4E-19 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_11670 cdef6ad5d33fc584d50f62b1a5c8bb0b 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 438 1.0E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_11670 cdef6ad5d33fc584d50f62b1a5c8bb0b 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 424 1.0E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_11670 cdef6ad5d33fc584d50f62b1a5c8bb0b 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 463 1.0E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_11670 cdef6ad5d33fc584d50f62b1a5c8bb0b 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 469 482 1.0E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_11670 cdef6ad5d33fc584d50f62b1a5c8bb0b 501 SUPERFAMILY SSF47384 227 309 1.79E-19 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_11670 cdef6ad5d33fc584d50f62b1a5c8bb0b 501 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 356 483 1.3E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_11670 cdef6ad5d33fc584d50f62b1a5c8bb0b 501 Gene3D G3DSA:1.10.287.130 242 309 2.9E-24 T 14-10-2018 TSH58p_11670 cdef6ad5d33fc584d50f62b1a5c8bb0b 501 Gene3D G3DSA:3.30.450.20 103 241 1.2E-7 T 14-10-2018 TSH58p_11670 cdef6ad5d33fc584d50f62b1a5c8bb0b 501 Gene3D G3DSA:3.30.565.10 319 493 8.9E-44 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_11670 cdef6ad5d33fc584d50f62b1a5c8bb0b 501 SMART SM00387 356 485 6.5E-38 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_27750 4b291beb0bae247a16862d30deee1f21 324 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 33 307 1.3E-67 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 TSH58p_27750 4b291beb0bae247a16862d30deee1f21 324 SUPERFAMILY SSF53850 134 273 5.04E-7 T 14-10-2018 TSH58p_27750 4b291beb0bae247a16862d30deee1f21 324 Gene3D G3DSA:3.40.190.170 26 324 3.3E-90 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily TSH58p_27750 4b291beb0bae247a16862d30deee1f21 324 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 31 286 3.0E-53 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 TSH58p_27750 4b291beb0bae247a16862d30deee1f21 324 PIRSF PIRSF006470 1 324 1.1E-68 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 TSH58p_28290 57a4fa7082dbd7cbfca5d4f537137990 269 SUPERFAMILY SSF81901 30 89 3.01E-6 T 14-10-2018 TSH58p_28290 57a4fa7082dbd7cbfca5d4f537137990 269 Gene3D G3DSA:1.25.40.10 23 97 4.6E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_28290 57a4fa7082dbd7cbfca5d4f537137990 269 Pfam PF01464 Transglycosylase SLT domain 124 227 7.1E-27 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 TSH58p_28290 57a4fa7082dbd7cbfca5d4f537137990 269 SUPERFAMILY SSF53955 94 241 9.76E-46 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily TSH58p_28290 57a4fa7082dbd7cbfca5d4f537137990 269 Gene3D G3DSA:1.10.530.10 116 247 4.1E-42 T 14-10-2018 TSH58p_28290 57a4fa7082dbd7cbfca5d4f537137990 269 SMART SM00671 46 81 1.4E-4 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_00370 77c890190143917cbe2534e34fa36908 178 SMART SM00347 52 150 2.2E-4 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_00370 77c890190143917cbe2534e34fa36908 178 ProSitePatterns PS01117 MarR-type HTH domain signature. 90 124 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site TSH58p_00370 77c890190143917cbe2534e34fa36908 178 Pfam PF13463 Winged helix DNA-binding domain 61 124 2.0E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_00370 77c890190143917cbe2534e34fa36908 178 SUPERFAMILY SSF46785 28 170 2.53E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_00370 77c890190143917cbe2534e34fa36908 178 Gene3D G3DSA:1.10.10.10 2 166 1.2E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_32390 be920250a5e4c223c9a5819561722f98 299 Pfam PF00701 Dihydrodipicolinate synthetase family 8 291 2.4E-66 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_32390 be920250a5e4c223c9a5819561722f98 299 SUPERFAMILY SSF51569 8 292 3.24E-80 T 14-10-2018 TSH58p_32390 be920250a5e4c223c9a5819561722f98 299 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 11 292 4.3E-67 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSH58p_32390 be920250a5e4c223c9a5819561722f98 299 Gene3D G3DSA:3.20.20.70 5 295 1.8E-85 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_32390 be920250a5e4c223c9a5819561722f98 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 108 124 3.0E-17 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_32390 be920250a5e4c223c9a5819561722f98 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 76 94 3.0E-17 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_32390 be920250a5e4c223c9a5819561722f98 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 133 150 3.0E-17 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_32390 be920250a5e4c223c9a5819561722f98 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 41 62 3.0E-17 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_32390 be920250a5e4c223c9a5819561722f98 299 PIRSF PIRSF001365 4 298 5.3E-74 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_32390 be920250a5e4c223c9a5819561722f98 299 SMART SM01130 7 294 4.9E-95 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_32390 be920250a5e4c223c9a5819561722f98 299 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 7 292 39.837 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSH58p_06605 07a8153330d47e17293f29265366c400 312 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 40 270 29.565 T 14-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TSH58p_06605 07a8153330d47e17293f29265366c400 312 SUPERFAMILY SSF69796 37 271 1.31E-71 T 14-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TSH58p_06605 07a8153330d47e17293f29265366c400 312 Gene3D G3DSA:3.30.1360.170 30 277 9.5E-75 T 14-10-2018 TSH58p_06605 07a8153330d47e17293f29265366c400 312 Pfam PF02511 Thymidylate synthase complementing protein 46 256 1.9E-57 T 14-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TSH58p_06605 07a8153330d47e17293f29265366c400 312 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 44 262 1.5E-65 T 14-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TSH58p_12610 c1b026e64be5f22fab2ea182797ed782 383 SUPERFAMILY SSF53448 42 325 5.72E-36 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_12610 c1b026e64be5f22fab2ea182797ed782 383 Pfam PF00535 Glycosyl transferase family 2 43 162 5.0E-17 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_12610 c1b026e64be5f22fab2ea182797ed782 383 Gene3D G3DSA:3.90.550.10 33 244 4.8E-32 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_07620 3a5431f6d907361da3b8c2453c0ef95b 297 TIGRFAM TIGR02662 dinitro_DRAG: ADP-ribosyl-[dinitrogen reductase] hydrolase 6 291 1.4E-156 T 14-10-2018 IPR013479 ADP-ribosyl-dinitrogen reductase hydrolase TSH58p_07620 3a5431f6d907361da3b8c2453c0ef95b 297 Gene3D G3DSA:1.10.4080.10 1 297 4.1E-117 T 14-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily TSH58p_07620 3a5431f6d907361da3b8c2453c0ef95b 297 Pfam PF03747 ADP-ribosylglycohydrolase 12 267 3.1E-50 T 14-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 TSH58p_07620 3a5431f6d907361da3b8c2453c0ef95b 297 SUPERFAMILY SSF101478 5 289 3.4E-73 T 14-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily TSH58p_13500 392a77b99942ed2f81f51e29292b40dd 309 Gene3D G3DSA:3.90.79.10 174 308 4.2E-35 T 14-10-2018 TSH58p_13500 392a77b99942ed2f81f51e29292b40dd 309 Gene3D G3DSA:3.90.79.20 45 172 2.3E-7 T 14-10-2018 TSH58p_13500 392a77b99942ed2f81f51e29292b40dd 309 Pfam PF00293 NUDIX domain 175 279 1.8E-13 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TSH58p_13500 392a77b99942ed2f81f51e29292b40dd 309 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 138 171 9.6E-8 T 14-10-2018 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 TSH58p_13500 392a77b99942ed2f81f51e29292b40dd 309 Pfam PF09296 NADH pyrophosphatase-like rudimentary NUDIX domain 73 136 2.3E-11 T 14-10-2018 IPR015375 NADH pyrophosphatase-like, N-terminal GO:0016787 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 TSH58p_13500 392a77b99942ed2f81f51e29292b40dd 309 SUPERFAMILY SSF55811 123 305 1.9E-40 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TSH58p_13740 833165ccb20f30912cc08b6e70e2e2e7 376 SUPERFAMILY SSF88697 285 375 4.25E-27 T 14-10-2018 IPR015947 PUA-like superfamily TSH58p_13740 833165ccb20f30912cc08b6e70e2e2e7 376 Pfam PF01472 PUA domain 286 359 3.6E-24 T 14-10-2018 IPR002478 PUA domain GO:0003723 TSH58p_13740 833165ccb20f30912cc08b6e70e2e2e7 376 SUPERFAMILY SSF53633 9 252 6.94E-63 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSH58p_13740 833165ccb20f30912cc08b6e70e2e2e7 376 SMART SM00359 286 368 4.9E-21 T 14-10-2018 IPR002478 PUA domain GO:0003723 TSH58p_13740 833165ccb20f30912cc08b6e70e2e2e7 376 Hamap MF_00456 Glutamate 5-kinase [proB]. 9 268 35.571 T 14-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 TSH58p_13740 833165ccb20f30912cc08b6e70e2e2e7 376 PIRSF PIRSF000729 5 376 1.4E-124 T 14-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 TSH58p_13740 833165ccb20f30912cc08b6e70e2e2e7 376 Pfam PF00696 Amino acid kinase family 10 239 2.9E-41 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TSH58p_13740 833165ccb20f30912cc08b6e70e2e2e7 376 Gene3D G3DSA:2.30.130.10 275 376 3.1E-32 T 14-10-2018 IPR036974 PUA domain superfamily GO:0003723 TSH58p_13740 833165ccb20f30912cc08b6e70e2e2e7 376 Gene3D G3DSA:3.40.1160.10 3 272 9.9E-82 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSH58p_13740 833165ccb20f30912cc08b6e70e2e2e7 376 TIGRFAM TIGR01027 proB: glutamate 5-kinase 9 374 2.7E-122 T 14-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 TSH58p_13740 833165ccb20f30912cc08b6e70e2e2e7 376 PRINTS PR00474 Glutamate 5-kinase family signature 47 61 1.7E-47 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TSH58p_13740 833165ccb20f30912cc08b6e70e2e2e7 376 PRINTS PR00474 Glutamate 5-kinase family signature 121 142 1.7E-47 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TSH58p_13740 833165ccb20f30912cc08b6e70e2e2e7 376 PRINTS PR00474 Glutamate 5-kinase family signature 214 234 1.7E-47 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TSH58p_13740 833165ccb20f30912cc08b6e70e2e2e7 376 PRINTS PR00474 Glutamate 5-kinase family signature 153 180 1.7E-47 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TSH58p_13740 833165ccb20f30912cc08b6e70e2e2e7 376 PRINTS PR00474 Glutamate 5-kinase family signature 81 109 1.7E-47 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TSH58p_18320 19c37953a513739b65e05f4d61946cb8 342 SUPERFAMILY SSF51120 68 200 1.31E-9 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_18320 19c37953a513739b65e05f4d61946cb8 342 SUPERFAMILY SSF51120 165 333 1.67E-25 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_18320 19c37953a513739b65e05f4d61946cb8 342 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 251 269 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_18320 19c37953a513739b65e05f4d61946cb8 342 Gene3D G3DSA:2.150.10.10 191 238 5.4E-8 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_18320 19c37953a513739b65e05f4d61946cb8 342 Gene3D G3DSA:2.150.10.10 114 190 4.2E-5 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_18320 19c37953a513739b65e05f4d61946cb8 342 PRINTS PR00313 NodO calcium binding signature 255 263 1.2E-11 T 14-10-2018 TSH58p_18320 19c37953a513739b65e05f4d61946cb8 342 PRINTS PR00313 NodO calcium binding signature 225 233 1.2E-11 T 14-10-2018 TSH58p_18320 19c37953a513739b65e05f4d61946cb8 342 PRINTS PR00313 NodO calcium binding signature 124 135 1.2E-11 T 14-10-2018 TSH58p_18320 19c37953a513739b65e05f4d61946cb8 342 PRINTS PR00313 NodO calcium binding signature 264 273 1.2E-11 T 14-10-2018 TSH58p_18320 19c37953a513739b65e05f4d61946cb8 342 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 225 235 1.5 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18320 19c37953a513739b65e05f4d61946cb8 342 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 254 271 0.002 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18320 19c37953a513739b65e05f4d61946cb8 342 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 190 205 7.6 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18320 19c37953a513739b65e05f4d61946cb8 342 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 124 134 3.4 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18320 19c37953a513739b65e05f4d61946cb8 342 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 164 175 31.0 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18320 19c37953a513739b65e05f4d61946cb8 342 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 138 152 0.18 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18320 19c37953a513739b65e05f4d61946cb8 342 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 209 223 0.023 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18320 19c37953a513739b65e05f4d61946cb8 342 Gene3D G3DSA:2.150.10.10 239 342 3.9E-15 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_01830 c9eb780f3009dc7811d284e8240b87d3 397 Gene3D G3DSA:1.20.1250.20 10 193 7.8E-9 T 14-10-2018 TSH58p_01830 c9eb780f3009dc7811d284e8240b87d3 397 PRINTS PR01656 Helicobacter pylori vacuolating cytotoxin signature 293 318 5.5E-5 T 14-10-2018 IPR003842 Vacuolating cytotoxin GO:0005576|GO:0009405 TSH58p_01830 c9eb780f3009dc7811d284e8240b87d3 397 PRINTS PR01656 Helicobacter pylori vacuolating cytotoxin signature 4 22 5.5E-5 T 14-10-2018 IPR003842 Vacuolating cytotoxin GO:0005576|GO:0009405 TSH58p_01830 c9eb780f3009dc7811d284e8240b87d3 397 PRINTS PR01656 Helicobacter pylori vacuolating cytotoxin signature 39 65 5.5E-5 T 14-10-2018 IPR003842 Vacuolating cytotoxin GO:0005576|GO:0009405 TSH58p_01830 c9eb780f3009dc7811d284e8240b87d3 397 Pfam PF07690 Major Facilitator Superfamily 241 385 2.4E-11 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_01830 c9eb780f3009dc7811d284e8240b87d3 397 SUPERFAMILY SSF103473 12 385 6.67E-33 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_01830 c9eb780f3009dc7811d284e8240b87d3 397 Gene3D G3DSA:1.20.1250.20 204 393 1.2E-13 T 14-10-2018 TSH58p_04535 7e29c861f4b5b73955d309923e6a4516 265 PIRSF PIRSF005902 1 258 6.1E-79 T 14-10-2018 IPR001130 TatD family GO:0016788 TSH58p_04535 7e29c861f4b5b73955d309923e6a4516 265 Gene3D G3DSA:3.20.20.140 1 257 6.0E-94 T 14-10-2018 TSH58p_04535 7e29c861f4b5b73955d309923e6a4516 265 Pfam PF01026 TatD related DNase 3 254 9.8E-80 T 14-10-2018 IPR001130 TatD family GO:0016788 TSH58p_04535 7e29c861f4b5b73955d309923e6a4516 265 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 254 1.2E-86 T 14-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 TSH58p_04535 7e29c861f4b5b73955d309923e6a4516 265 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 125 135 - T 14-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 TSH58p_04535 7e29c861f4b5b73955d309923e6a4516 265 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 14-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 TSH58p_04535 7e29c861f4b5b73955d309923e6a4516 265 SUPERFAMILY SSF51556 2 255 4.48E-91 T 14-10-2018 IPR032466 Metal-dependent hydrolase TSH58p_28510 096757c7813c7488c074087df7c22279 350 Gene3D G3DSA:3.40.50.2300 61 319 1.9E-43 T 14-10-2018 TSH58p_28510 096757c7813c7488c074087df7c22279 350 Pfam PF04392 ABC transporter substrate binding protein 83 347 1.5E-29 T 14-10-2018 IPR007487 ABC transporter, substrate-binding protein TSH58p_28510 096757c7813c7488c074087df7c22279 350 Gene3D G3DSA:3.40.50.2300 160 344 1.9E-43 T 14-10-2018 TSH58p_05930 b243af09acfc15f3b85e6c6579ea7067 90 SMART SM00411 1 90 4.1E-42 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_05930 b243af09acfc15f3b85e6c6579ea7067 90 Gene3D G3DSA:4.10.520.10 1 90 4.2E-36 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 TSH58p_05930 b243af09acfc15f3b85e6c6579ea7067 90 SUPERFAMILY SSF47729 1 89 6.62E-32 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 TSH58p_05930 b243af09acfc15f3b85e6c6579ea7067 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 14-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 TSH58p_05930 b243af09acfc15f3b85e6c6579ea7067 90 Pfam PF00216 Bacterial DNA-binding protein 1 89 7.5E-34 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_05930 b243af09acfc15f3b85e6c6579ea7067 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.2E-17 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_05930 b243af09acfc15f3b85e6c6579ea7067 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 1.2E-17 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_05930 b243af09acfc15f3b85e6c6579ea7067 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 1.2E-17 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_24790 ce074f202eb51b0a0be763f5873e7024 716 SMART SM00388 342 407 1.8E-6 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_24790 ce074f202eb51b0a0be763f5873e7024 716 SMART SM00387 451 562 7.1E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_24790 ce074f202eb51b0a0be763f5873e7024 716 SUPERFAMILY SSF52172 585 709 2.42E-26 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_24790 ce074f202eb51b0a0be763f5873e7024 716 Pfam PF00072 Response regulator receiver domain 586 698 8.2E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_24790 ce074f202eb51b0a0be763f5873e7024 716 SUPERFAMILY SSF47384 325 407 4.32E-10 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_24790 ce074f202eb51b0a0be763f5873e7024 716 Gene3D G3DSA:1.10.287.130 303 405 8.4E-11 T 14-10-2018 TSH58p_24790 ce074f202eb51b0a0be763f5873e7024 716 SMART SM00448 584 698 4.3E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_24790 ce074f202eb51b0a0be763f5873e7024 716 Pfam PF00512 His Kinase A (phospho-acceptor) domain 342 407 8.1E-7 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_24790 ce074f202eb51b0a0be763f5873e7024 716 Gene3D G3DSA:3.40.50.2300 576 713 1.1E-23 T 14-10-2018 TSH58p_24790 ce074f202eb51b0a0be763f5873e7024 716 SUPERFAMILY SSF55874 398 563 1.15E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_24790 ce074f202eb51b0a0be763f5873e7024 716 Gene3D G3DSA:3.30.565.10 407 567 1.7E-33 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_24790 ce074f202eb51b0a0be763f5873e7024 716 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 452 561 3.2E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_24790 ce074f202eb51b0a0be763f5873e7024 716 PRINTS PR00344 Bacterial sensor protein C-terminal signature 487 501 1.5E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_24790 ce074f202eb51b0a0be763f5873e7024 716 PRINTS PR00344 Bacterial sensor protein C-terminal signature 505 515 1.5E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_24790 ce074f202eb51b0a0be763f5873e7024 716 PRINTS PR00344 Bacterial sensor protein C-terminal signature 546 559 1.5E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_24790 ce074f202eb51b0a0be763f5873e7024 716 PRINTS PR00344 Bacterial sensor protein C-terminal signature 522 540 1.5E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_04840 fe912bb875198bf60db3395edffb7fbb 322 Pfam PF00480 ROK family 13 308 4.7E-76 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TSH58p_04840 fe912bb875198bf60db3395edffb7fbb 322 ProSitePatterns PS01125 ROK family signature. 141 168 - T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TSH58p_04840 fe912bb875198bf60db3395edffb7fbb 322 Gene3D G3DSA:3.30.420.40 130 297 2.7E-82 T 14-10-2018 TSH58p_04840 fe912bb875198bf60db3395edffb7fbb 322 SUPERFAMILY SSF53067 13 308 4.11E-62 T 14-10-2018 TSH58p_04840 fe912bb875198bf60db3395edffb7fbb 322 Gene3D G3DSA:3.30.420.40 14 304 2.7E-82 T 14-10-2018 TSH58p_01410 56a044c60ccfc849dda6767795c190cb 262 Gene3D G3DSA:1.10.12.10 205 262 3.1E-16 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal TSH58p_01410 56a044c60ccfc849dda6767795c190cb 262 Gene3D G3DSA:3.90.226.10 1 204 3.7E-72 T 14-10-2018 TSH58p_01410 56a044c60ccfc849dda6767795c190cb 262 SUPERFAMILY SSF52096 3 261 2.77E-91 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_01410 56a044c60ccfc849dda6767795c190cb 262 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 262 3.9E-68 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TSH58p_29660 c193f4747f62b3df52337d9648607816 340 SUPERFAMILY SSF63829 66 315 1.9E-9 T 14-10-2018 TSH58p_29660 c193f4747f62b3df52337d9648607816 340 Pfam PF13449 Esterase-like activity of phytase 64 314 1.1E-40 T 14-10-2018 IPR027372 Phytase-like domain TSH58p_29660 c193f4747f62b3df52337d9648607816 340 PIRSF PIRSF031900 15 330 8.5E-52 T 14-10-2018 IPR014567 Uncharacterised conserved protein UCP031900 TSH58p_00435 7c3d90dfe7eef17637fc01413102b88b 286 SUPERFAMILY SSF52540 26 264 1.22E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_00435 7c3d90dfe7eef17637fc01413102b88b 286 SMART SM00382 53 244 2.0E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_00435 7c3d90dfe7eef17637fc01413102b88b 286 Gene3D G3DSA:3.40.50.300 23 266 1.4E-55 T 14-10-2018 TSH58p_00435 7c3d90dfe7eef17637fc01413102b88b 286 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_00435 7c3d90dfe7eef17637fc01413102b88b 286 Pfam PF00005 ABC transporter 44 192 5.5E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_21300 573768a721c5e123df60f334c14546d4 268 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 140 152 - T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 TSH58p_21300 573768a721c5e123df60f334c14546d4 268 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 4 264 1.5E-73 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 TSH58p_21300 573768a721c5e123df60f334c14546d4 268 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 11 259 1.1E-74 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 TSH58p_21300 573768a721c5e123df60f334c14546d4 268 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 8 265 19.299 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 TSH58p_24060 f5d2832934dc6a3042c8e8ad721f0513 246 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 1 226 5.2E-45 T 14-10-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 TSH58p_24060 f5d2832934dc6a3042c8e8ad721f0513 246 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 3 241 4.5E-74 T 14-10-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 TSH58p_14285 3cd9ec3da8abeef2851066c6c5f2da54 587 ProSitePatterns PS01135 FtsZ protein signature 2. 100 121 - T 14-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TSH58p_14285 3cd9ec3da8abeef2851066c6c5f2da54 587 SUPERFAMILY SSF52490 15 211 1.05E-69 T 14-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TSH58p_14285 3cd9ec3da8abeef2851066c6c5f2da54 587 Gene3D G3DSA:3.40.50.1440 8 223 4.1E-78 T 14-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TSH58p_14285 3cd9ec3da8abeef2851066c6c5f2da54 587 ProSitePatterns PS01134 FtsZ protein signature 1. 47 81 - T 14-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TSH58p_14285 3cd9ec3da8abeef2851066c6c5f2da54 587 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 12 343 37.55 T 14-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 TSH58p_14285 3cd9ec3da8abeef2851066c6c5f2da54 587 Gene3D G3DSA:3.30.1330.20 228 336 2.0E-38 T 14-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 TSH58p_14285 3cd9ec3da8abeef2851066c6c5f2da54 587 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 10 325 2.1E-121 T 14-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 TSH58p_14285 3cd9ec3da8abeef2851066c6c5f2da54 587 PRINTS PR00423 Cell division protein FtsZ signature 129 150 6.8E-50 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSH58p_14285 3cd9ec3da8abeef2851066c6c5f2da54 587 PRINTS PR00423 Cell division protein FtsZ signature 101 121 6.8E-50 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSH58p_14285 3cd9ec3da8abeef2851066c6c5f2da54 587 PRINTS PR00423 Cell division protein FtsZ signature 192 214 6.8E-50 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSH58p_14285 3cd9ec3da8abeef2851066c6c5f2da54 587 PRINTS PR00423 Cell division protein FtsZ signature 215 236 6.8E-50 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSH58p_14285 3cd9ec3da8abeef2851066c6c5f2da54 587 Pfam PF12327 FtsZ family, C-terminal domain 225 320 7.8E-39 T 14-10-2018 IPR024757 Cell division protein FtsZ, C-terminal TSH58p_14285 3cd9ec3da8abeef2851066c6c5f2da54 587 SUPERFAMILY SSF55307 207 321 3.2E-43 T 14-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 TSH58p_14285 3cd9ec3da8abeef2851066c6c5f2da54 587 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 16 177 1.8E-38 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSH58p_14285 3cd9ec3da8abeef2851066c6c5f2da54 587 SMART SM00865 210 328 3.6E-58 T 14-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 TSH58p_14285 3cd9ec3da8abeef2851066c6c5f2da54 587 SMART SM00864 16 208 1.3E-106 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSH58p_25015 55d9d84c00f71358b29a2692ead4ed6e 254 SUPERFAMILY SSF46785 176 252 3.96E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_25015 55d9d84c00f71358b29a2692ead4ed6e 254 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 203 219 3.6E-6 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_25015 55d9d84c00f71358b29a2692ead4ed6e 254 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 219 234 3.6E-6 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_25015 55d9d84c00f71358b29a2692ead4ed6e 254 SMART SM00419 197 246 4.7E-6 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_25015 55d9d84c00f71358b29a2692ead4ed6e 254 Pfam PF13545 Crp-like helix-turn-helix domain 178 252 2.2E-15 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_25015 55d9d84c00f71358b29a2692ead4ed6e 254 Pfam PF00027 Cyclic nucleotide-binding domain 70 146 4.0E-12 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_25015 55d9d84c00f71358b29a2692ead4ed6e 254 Gene3D G3DSA:2.60.120.10 62 174 5.3E-35 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_25015 55d9d84c00f71358b29a2692ead4ed6e 254 SUPERFAMILY SSF51206 38 173 3.27E-26 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like TSH58p_25015 55d9d84c00f71358b29a2692ead4ed6e 254 Gene3D G3DSA:1.10.10.10 175 254 2.5E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_25015 55d9d84c00f71358b29a2692ead4ed6e 254 SMART SM00100 43 161 1.1E-14 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_21695 3af43a73631a2ed2757991a2e236aae8 372 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 301 312 4.1E-7 T 14-10-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 TSH58p_21695 3af43a73631a2ed2757991a2e236aae8 372 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 185 201 4.1E-7 T 14-10-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 TSH58p_21695 3af43a73631a2ed2757991a2e236aae8 372 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 164 178 4.1E-7 T 14-10-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 TSH58p_21695 3af43a73631a2ed2757991a2e236aae8 372 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 250 264 4.1E-7 T 14-10-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 TSH58p_21695 3af43a73631a2ed2757991a2e236aae8 372 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 141 160 4.1E-7 T 14-10-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 TSH58p_21695 3af43a73631a2ed2757991a2e236aae8 372 SUPERFAMILY SSF55869 41 101 4.45E-22 T 14-10-2018 IPR035447 DNA topoisomerase I, N-terminal TSH58p_21695 3af43a73631a2ed2757991a2e236aae8 372 SUPERFAMILY SSF56349 97 320 1.53E-71 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TSH58p_21695 3af43a73631a2ed2757991a2e236aae8 372 Gene3D G3DSA:1.10.132.120 109 348 1.6E-95 T 14-10-2018 TSH58p_21695 3af43a73631a2ed2757991a2e236aae8 372 Pfam PF01028 Eukaryotic DNA topoisomerase I, catalytic core 106 310 1.1E-32 T 14-10-2018 IPR013500 DNA topoisomerase I, catalytic core, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 TSH58p_21695 3af43a73631a2ed2757991a2e236aae8 372 Gene3D G3DSA:3.30.66.10 23 107 2.6E-33 T 14-10-2018 IPR035447 DNA topoisomerase I, N-terminal TSH58p_21695 3af43a73631a2ed2757991a2e236aae8 372 Gene3D G3DSA:3.90.15.10 132 251 1.6E-95 T 14-10-2018 IPR014711 DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 TSH58p_29815 337b2b6cf23a399a3f38cb8dc619a04e 670 Gene3D G3DSA:3.40.50.11380 290 640 5.9E-155 T 14-10-2018 TSH58p_29815 337b2b6cf23a399a3f38cb8dc619a04e 670 Pfam PF13181 Tetratricopeptide repeat 117 145 0.0029 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29815 337b2b6cf23a399a3f38cb8dc619a04e 670 Pfam PF13844 Glycosyl transferase family 41 299 445 5.0E-44 T 14-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 TSH58p_29815 337b2b6cf23a399a3f38cb8dc619a04e 670 Pfam PF13844 Glycosyl transferase family 41 459 652 2.3E-50 T 14-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 TSH58p_29815 337b2b6cf23a399a3f38cb8dc619a04e 670 SUPERFAMILY SSF53756 303 648 8.79E-10 T 14-10-2018 TSH58p_29815 337b2b6cf23a399a3f38cb8dc619a04e 670 SMART SM00028 147 180 1.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29815 337b2b6cf23a399a3f38cb8dc619a04e 670 SMART SM00028 181 214 52.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29815 337b2b6cf23a399a3f38cb8dc619a04e 670 SMART SM00028 45 78 34.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29815 337b2b6cf23a399a3f38cb8dc619a04e 670 SMART SM00028 79 112 20.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29815 337b2b6cf23a399a3f38cb8dc619a04e 670 SMART SM00028 113 146 0.39 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29815 337b2b6cf23a399a3f38cb8dc619a04e 670 SUPERFAMILY SSF48452 11 241 6.96E-32 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29815 337b2b6cf23a399a3f38cb8dc619a04e 670 Gene3D G3DSA:3.40.50.2000 456 634 5.9E-155 T 14-10-2018 TSH58p_29815 337b2b6cf23a399a3f38cb8dc619a04e 670 Gene3D G3DSA:1.25.40.10 2 145 1.9E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29815 337b2b6cf23a399a3f38cb8dc619a04e 670 Gene3D G3DSA:1.25.40.10 189 252 6.3E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29815 337b2b6cf23a399a3f38cb8dc619a04e 670 Gene3D G3DSA:1.25.40.10 149 188 5.1E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29815 337b2b6cf23a399a3f38cb8dc619a04e 670 Pfam PF13414 TPR repeat 159 194 1.6E-6 T 14-10-2018 TSH58p_15915 80793cfadd6b693f78d94c58fa49257c 391 TIGRFAM TIGR01365 serC_2: phosphoserine aminotransferase 6 384 3.4E-192 T 14-10-2018 IPR006271 Phosphoserine aminotransferase, Methanosarcina-type GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52 TSH58p_15915 80793cfadd6b693f78d94c58fa49257c 391 PIRSF PIRSF000525 3 385 3.1E-46 T 14-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 TSH58p_15915 80793cfadd6b693f78d94c58fa49257c 391 Gene3D G3DSA:3.90.1150.10 269 384 4.6E-14 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_15915 80793cfadd6b693f78d94c58fa49257c 391 Gene3D G3DSA:3.40.640.10 26 266 8.9E-41 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_15915 80793cfadd6b693f78d94c58fa49257c 391 SUPERFAMILY SSF53383 7 381 9.73E-68 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_06990 dec265cdd8aec6144cf3fdbfcbe3f7a1 255 SUPERFAMILY SSF88874 28 166 1.26E-25 T 14-10-2018 TSH58p_06990 dec265cdd8aec6144cf3fdbfcbe3f7a1 255 Gene3D G3DSA:4.10.1070.10 86 104 6.9E-14 T 14-10-2018 TSH58p_06990 dec265cdd8aec6144cf3fdbfcbe3f7a1 255 Gene3D G3DSA:3.90.1340.10 32 85 6.9E-14 T 14-10-2018 IPR037053 Phage tail collar domain superfamily TSH58p_06990 dec265cdd8aec6144cf3fdbfcbe3f7a1 255 Pfam PF07484 Phage Tail Collar Domain 33 88 6.7E-19 T 14-10-2018 IPR011083 Phage tail collar domain TSH58p_00410 2496aaf95a8a09632733efc15f4c287b 268 SUPERFAMILY SSF52540 2 251 1.01E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_00410 2496aaf95a8a09632733efc15f4c287b 268 SMART SM00382 26 236 5.8E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_00410 2496aaf95a8a09632733efc15f4c287b 268 Pfam PF00005 ABC transporter 17 179 1.8E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_00410 2496aaf95a8a09632733efc15f4c287b 268 Gene3D G3DSA:3.40.50.300 1 267 5.5E-63 T 14-10-2018 TSH58p_00410 2496aaf95a8a09632733efc15f4c287b 268 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 228 250 5.3E-12 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSH58p_07945 e37e59a86959a0278611dbfc5ce10dc4 232 SMART SM01007 11 185 7.5E-62 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal TSH58p_07945 e37e59a86959a0278611dbfc5ce10dc4 232 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 12 185 4.5E-47 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal TSH58p_07945 e37e59a86959a0278611dbfc5ce10dc4 232 Gene3D G3DSA:3.40.225.10 6 215 3.1E-69 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TSH58p_07945 e37e59a86959a0278611dbfc5ce10dc4 232 SUPERFAMILY SSF53639 2 210 2.94E-63 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TSH58p_18565 434a25e8946854c9ae5adb4241b40d6e 268 SUPERFAMILY SSF46785 40 111 2.09E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_18565 434a25e8946854c9ae5adb4241b40d6e 268 Pfam PF07729 FCD domain 119 240 1.5E-26 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_18565 434a25e8946854c9ae5adb4241b40d6e 268 Gene3D G3DSA:1.10.10.10 35 108 4.3E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_18565 434a25e8946854c9ae5adb4241b40d6e 268 SMART SM00345 49 107 3.1E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_18565 434a25e8946854c9ae5adb4241b40d6e 268 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 81 97 2.0E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_18565 434a25e8946854c9ae5adb4241b40d6e 268 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 67 81 2.0E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_18565 434a25e8946854c9ae5adb4241b40d6e 268 Pfam PF00392 Bacterial regulatory proteins, gntR family 47 107 4.3E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_18565 434a25e8946854c9ae5adb4241b40d6e 268 SMART SM00895 117 241 4.0E-20 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_18565 434a25e8946854c9ae5adb4241b40d6e 268 Gene3D G3DSA:1.20.120.530 115 253 1.1E-26 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_18565 434a25e8946854c9ae5adb4241b40d6e 268 SUPERFAMILY SSF48008 116 243 1.96E-26 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_21445 434a25e8946854c9ae5adb4241b40d6e 268 SUPERFAMILY SSF46785 40 111 2.09E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_21445 434a25e8946854c9ae5adb4241b40d6e 268 Pfam PF07729 FCD domain 119 240 1.5E-26 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_21445 434a25e8946854c9ae5adb4241b40d6e 268 Gene3D G3DSA:1.10.10.10 35 108 4.3E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_21445 434a25e8946854c9ae5adb4241b40d6e 268 SMART SM00345 49 107 3.1E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_21445 434a25e8946854c9ae5adb4241b40d6e 268 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 81 97 2.0E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_21445 434a25e8946854c9ae5adb4241b40d6e 268 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 67 81 2.0E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_21445 434a25e8946854c9ae5adb4241b40d6e 268 Pfam PF00392 Bacterial regulatory proteins, gntR family 47 107 4.3E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_21445 434a25e8946854c9ae5adb4241b40d6e 268 SMART SM00895 117 241 4.0E-20 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_21445 434a25e8946854c9ae5adb4241b40d6e 268 Gene3D G3DSA:1.20.120.530 115 253 1.1E-26 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_21445 434a25e8946854c9ae5adb4241b40d6e 268 SUPERFAMILY SSF48008 116 243 1.96E-26 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_00555 faaba15ab67ac836991b55b7ea3df0ae 708 Pfam PF00535 Glycosyl transferase family 2 22 137 2.3E-15 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_00555 faaba15ab67ac836991b55b7ea3df0ae 708 Gene3D G3DSA:3.90.550.10 17 255 2.5E-29 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_00555 faaba15ab67ac836991b55b7ea3df0ae 708 SUPERFAMILY SSF53448 22 230 2.53E-33 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_30460 17c604b87ce26b747a480ac5a0b1f0af 93 Gene3D G3DSA:3.30.2270.10 1 93 5.5E-37 T 14-10-2018 IPR038561 Sarcosine oxidase subunit delta superfamily KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 TSH58p_30460 17c604b87ce26b747a480ac5a0b1f0af 93 Pfam PF04267 Sarcosine oxidase, delta subunit family 3 83 9.2E-35 T 14-10-2018 IPR006279 Sarcosine oxidase, delta subunit, heterotetrameric GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 TSH58p_27205 663c2c956144d666098e951e37def085 1063 SUPERFAMILY SSF48452 681 835 8.18E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_27205 663c2c956144d666098e951e37def085 1063 Pfam PF13191 AAA ATPase domain 257 450 3.7E-17 T 14-10-2018 TSH58p_27205 663c2c956144d666098e951e37def085 1063 Gene3D G3DSA:3.30.70.1230 56 247 1.9E-42 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_27205 663c2c956144d666098e951e37def085 1063 SMART SM00044 23 220 2.2E-8 T 14-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 TSH58p_27205 663c2c956144d666098e951e37def085 1063 SUPERFAMILY SSF55073 62 236 4.87E-41 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_27205 663c2c956144d666098e951e37def085 1063 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 66 231 4.7E-22 T 14-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 TSH58p_27205 663c2c956144d666098e951e37def085 1063 SUPERFAMILY SSF52540 256 510 9.0E-7 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_27205 663c2c956144d666098e951e37def085 1063 Gene3D G3DSA:1.25.40.10 846 1048 1.4E-17 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_27205 663c2c956144d666098e951e37def085 1063 Gene3D G3DSA:1.25.40.10 654 845 9.3E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_27205 663c2c956144d666098e951e37def085 1063 SUPERFAMILY SSF48452 853 1039 1.17E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_15730 20c705d5d0cbadae87fcb51f5237b2bd 170 SUPERFAMILY SSF55729 26 121 1.17E-15 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_15730 20c705d5d0cbadae87fcb51f5237b2bd 170 Gene3D G3DSA:3.40.630.30 10 141 1.0E-18 T 14-10-2018 TSH58p_15730 20c705d5d0cbadae87fcb51f5237b2bd 170 Pfam PF00583 Acetyltransferase (GNAT) family 42 113 2.9E-7 T 14-10-2018 IPR000182 GNAT domain TSH58p_03905 e1fc05aaf7cb806c0624f897788b9f45 183 Gene3D G3DSA:3.30.450.20 18 171 6.5E-21 T 14-10-2018 TSH58p_03905 e1fc05aaf7cb806c0624f897788b9f45 183 SUPERFAMILY SSF55785 25 109 6.6E-24 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_03905 e1fc05aaf7cb806c0624f897788b9f45 183 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 28 108 1.9E-11 T 14-10-2018 IPR000014 PAS domain TSH58p_03905 e1fc05aaf7cb806c0624f897788b9f45 183 Pfam PF00989 PAS fold 29 111 4.6E-11 T 14-10-2018 IPR013767 PAS fold GO:0006355 TSH58p_27425 c0b14fe1de8a36443670f974ab9aa3ab 240 Pfam PF02565 Recombination protein O C terminal 83 221 1.9E-29 T 14-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 TSH58p_27425 c0b14fe1de8a36443670f974ab9aa3ab 240 Pfam PF11967 Recombination protein O N terminal 1 76 2.6E-19 T 14-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal TSH58p_27425 c0b14fe1de8a36443670f974ab9aa3ab 240 SUPERFAMILY SSF50249 1 70 3.77E-12 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_27425 c0b14fe1de8a36443670f974ab9aa3ab 240 Hamap MF_00201 DNA repair protein RecO [recO]. 1 232 19.922 T 14-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 TSH58p_27425 c0b14fe1de8a36443670f974ab9aa3ab 240 ProDom PD202328 DNA REPAIR RECOMBINATION RECO DAMAGE O O RECO-RELATED RECOMBINATIONAL RP549 131 215 2.0E-17 T 14-10-2018 TSH58p_27425 c0b14fe1de8a36443670f974ab9aa3ab 240 TIGRFAM TIGR00613 reco: DNA repair protein RecO 4 176 1.1E-30 T 14-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 TSH58p_27425 c0b14fe1de8a36443670f974ab9aa3ab 240 SUPERFAMILY SSF57863 82 215 1.83E-14 T 14-10-2018 IPR037278 ARFGAP/RecO-like zinc finger TSH58p_27425 c0b14fe1de8a36443670f974ab9aa3ab 240 Gene3D G3DSA:2.40.50.140 1 73 2.4E-11 T 14-10-2018 TSH58p_21535 0f46f98c846fa7d2997ec19190362fac 82 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 6 66 5.0E-33 T 14-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 TSH58p_21535 0f46f98c846fa7d2997ec19190362fac 82 SUPERFAMILY SSF50182 7 72 5.65E-25 T 14-10-2018 IPR010920 LSM domain superfamily TSH58p_21535 0f46f98c846fa7d2997ec19190362fac 82 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 66 29.252 T 14-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 TSH58p_21535 0f46f98c846fa7d2997ec19190362fac 82 Gene3D G3DSA:2.30.30.100 1 78 3.0E-34 T 14-10-2018 TSH58p_21535 0f46f98c846fa7d2997ec19190362fac 82 Pfam PF17209 Hfq protein 8 70 3.0E-33 T 14-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 TSH58p_00625 bdf8f020e0e31e187f5b0a9f5b443476 731 SMART SM00387 457 600 9.1E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_00625 bdf8f020e0e31e187f5b0a9f5b443476 731 Pfam PF01627 Hpt domain 4 92 3.4E-11 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TSH58p_00625 bdf8f020e0e31e187f5b0a9f5b443476 731 SUPERFAMILY SSF55874 415 598 1.96E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_00625 bdf8f020e0e31e187f5b0a9f5b443476 731 Gene3D G3DSA:1.20.120.160 1 130 1.1E-26 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_00625 bdf8f020e0e31e187f5b0a9f5b443476 731 SMART SM00073 1 98 3.4E-13 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TSH58p_00625 bdf8f020e0e31e187f5b0a9f5b443476 731 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 461 599 1.4E-13 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_00625 bdf8f020e0e31e187f5b0a9f5b443476 731 Gene3D G3DSA:3.30.565.10 413 599 5.1E-51 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_00625 bdf8f020e0e31e187f5b0a9f5b443476 731 Gene3D G3DSA:1.10.287.560 344 412 1.2E-11 T 14-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 TSH58p_00625 bdf8f020e0e31e187f5b0a9f5b443476 731 Pfam PF01584 CheW-like domain 605 730 4.5E-16 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TSH58p_00625 bdf8f020e0e31e187f5b0a9f5b443476 731 PRINTS PR00344 Bacterial sensor protein C-terminal signature 560 578 1.4E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_00625 bdf8f020e0e31e187f5b0a9f5b443476 731 PRINTS PR00344 Bacterial sensor protein C-terminal signature 584 597 1.4E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_00625 bdf8f020e0e31e187f5b0a9f5b443476 731 PRINTS PR00344 Bacterial sensor protein C-terminal signature 502 516 1.4E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_00625 bdf8f020e0e31e187f5b0a9f5b443476 731 SMART SM01231 344 412 1.2E-14 T 14-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 TSH58p_00625 bdf8f020e0e31e187f5b0a9f5b443476 731 SUPERFAMILY SSF47384 345 413 7.45E-11 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_00625 bdf8f020e0e31e187f5b0a9f5b443476 731 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 345 411 6.2E-16 T 14-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 TSH58p_00625 bdf8f020e0e31e187f5b0a9f5b443476 731 SMART SM00260 592 731 2.1E-17 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TSH58p_00625 bdf8f020e0e31e187f5b0a9f5b443476 731 SUPERFAMILY SSF47226 2 112 2.62E-21 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_00625 bdf8f020e0e31e187f5b0a9f5b443476 731 Gene3D G3DSA:2.40.50.180 623 686 4.6E-24 T 14-10-2018 TSH58p_00625 bdf8f020e0e31e187f5b0a9f5b443476 731 Gene3D G3DSA:2.30.30.40 600 726 4.6E-24 T 14-10-2018 TSH58p_00625 bdf8f020e0e31e187f5b0a9f5b443476 731 SUPERFAMILY SSF50341 599 731 3.53E-23 T 14-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 TSH58p_14715 7c8bdfacb9d5b066be91bb60ad2fc2a7 316 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 24 313 1.1E-35 T 14-10-2018 IPR005218 Diacylglycerol/lipid kinase TSH58p_14715 7c8bdfacb9d5b066be91bb60ad2fc2a7 316 Gene3D G3DSA:2.60.200.40 153 308 7.5E-35 T 14-10-2018 TSH58p_14715 7c8bdfacb9d5b066be91bb60ad2fc2a7 316 Pfam PF00781 Diacylglycerol kinase catalytic domain 25 149 3.2E-28 T 14-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 TSH58p_14715 7c8bdfacb9d5b066be91bb60ad2fc2a7 316 SUPERFAMILY SSF111331 24 315 1.59E-68 T 14-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily TSH58p_14715 7c8bdfacb9d5b066be91bb60ad2fc2a7 316 SMART SM00046 25 155 3.1E-13 T 14-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 TSH58p_14715 7c8bdfacb9d5b066be91bb60ad2fc2a7 316 Gene3D G3DSA:3.40.50.10330 20 152 7.0E-34 T 14-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 TSH58p_23555 fb207dc1ac5c3abcc70caca1e540b43f 197 PIRSF PIRSF016661 9 196 9.7E-46 T 14-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 TSH58p_23555 fb207dc1ac5c3abcc70caca1e540b43f 197 Pfam PF02632 BioY family 48 189 1.3E-37 T 14-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 TSH58p_23555 fb207dc1ac5c3abcc70caca1e540b43f 197 Gene3D G3DSA:1.10.1760.20 22 193 8.0E-42 T 14-10-2018 TSH58p_31005 443315e04db640fa6acfd5769de03585 543 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 80 459 2.8E-92 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain TSH58p_31005 443315e04db640fa6acfd5769de03585 543 Gene3D G3DSA:3.90.76.10 51 216 4.7E-164 T 14-10-2018 TSH58p_31005 443315e04db640fa6acfd5769de03585 543 Gene3D G3DSA:3.10.105.10 298 517 4.7E-164 T 14-10-2018 TSH58p_31005 443315e04db640fa6acfd5769de03585 543 SUPERFAMILY SSF53850 37 539 1.99E-150 T 14-10-2018 TSH58p_31005 443315e04db640fa6acfd5769de03585 543 PIRSF PIRSF002741 4 541 1.2E-114 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TSH58p_31005 443315e04db640fa6acfd5769de03585 543 Gene3D G3DSA:3.40.190.10 217 530 4.7E-164 T 14-10-2018 TSH58p_28495 f1189904d8bca1db25a58e37229deacb 325 SUPERFAMILY SSF46785 246 323 2.01E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_28495 f1189904d8bca1db25a58e37229deacb 325 Gene3D G3DSA:3.40.50.2300 24 152 1.6E-14 T 14-10-2018 TSH58p_28495 f1189904d8bca1db25a58e37229deacb 325 Gene3D G3DSA:1.10.10.10 196 325 1.7E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_28495 f1189904d8bca1db25a58e37229deacb 325 SUPERFAMILY SSF52172 28 151 5.83E-17 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_28495 f1189904d8bca1db25a58e37229deacb 325 SMART SM00448 27 140 1.4E-4 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_28495 f1189904d8bca1db25a58e37229deacb 325 Pfam PF00072 Response regulator receiver domain 35 140 8.2E-11 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_28495 f1189904d8bca1db25a58e37229deacb 325 SMART SM00347 233 324 0.0059 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_28495 f1189904d8bca1db25a58e37229deacb 325 Pfam PF13463 Winged helix DNA-binding domain 255 310 9.2E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_15260 94949cceba09430d7609cf465c532307 161 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 151 4.1E-34 T 14-10-2018 IPR021131 Ribosomal protein L18e/L15P TSH58p_15260 94949cceba09430d7609cf465c532307 161 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 3 150 6.3E-44 T 14-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_15260 94949cceba09430d7609cf465c532307 161 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 4 153 20.224 T 14-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 TSH58p_15260 94949cceba09430d7609cf465c532307 161 Gene3D G3DSA:3.100.10.10 66 154 3.9E-16 T 14-10-2018 TSH58p_15260 94949cceba09430d7609cf465c532307 161 SUPERFAMILY SSF52080 5 151 2.49E-41 T 14-10-2018 IPR036227 Ribosomal L18e/L15P superfamily TSH58p_32255 796183c74b9d3f21e18fb968f0c76c13 276 Gene3D G3DSA:3.40.50.150 44 218 3.3E-29 T 14-10-2018 TSH58p_32255 796183c74b9d3f21e18fb968f0c76c13 276 Pfam PF05050 Methyltransferase FkbM domain 54 194 4.4E-14 T 14-10-2018 IPR006342 Methyltransferase FkbM TSH58p_32255 796183c74b9d3f21e18fb968f0c76c13 276 SUPERFAMILY SSF53335 25 214 8.44E-40 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_32255 796183c74b9d3f21e18fb968f0c76c13 276 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 53 189 1.5E-21 T 14-10-2018 IPR006342 Methyltransferase FkbM TSH58p_10590 95f9ed30c4503368035bdf6d0866cde8 297 Pfam PF08902 Domain of unknown function (DUF1848) 2 270 3.2E-82 T 14-10-2018 IPR014998 Protein of unknown function DUF1848 TSH58p_06370 025da85d7db796528f318d587482409b 275 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 22 241 4.2E-90 T 14-10-2018 IPR022488 Polyphosphate kinase-2-related TSH58p_06370 025da85d7db796528f318d587482409b 275 Gene3D G3DSA:3.40.50.300 3 263 1.6E-101 T 14-10-2018 TSH58p_06370 025da85d7db796528f318d587482409b 275 TIGRFAM TIGR03709 PPK2_rel_1: polyphosphate:nucleotide phosphotransferase, PPK2 family 6 251 3.8E-76 T 14-10-2018 IPR022300 Polyphosphate:nucleotide phosphotransferase, PPK2 GO:0006797|GO:0016776 KEGG: 00190+2.7.4.1 TSH58p_06370 025da85d7db796528f318d587482409b 275 PIRSF PIRSF028756 5 263 1.4E-84 T 14-10-2018 IPR016898 Polyphosphate kinase 2 KEGG: 00190+2.7.4.1 TSH58p_06370 025da85d7db796528f318d587482409b 275 SUPERFAMILY SSF52540 52 241 1.55E-23 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_16685 e9c077a3cc1c32cf42b5d7e0c24b4b59 407 Gene3D G3DSA:2.170.15.10 215 357 5.5E-8 T 14-10-2018 TSH58p_16685 e9c077a3cc1c32cf42b5d7e0c24b4b59 407 SUPERFAMILY SSF56973 209 384 1.57E-8 T 14-10-2018 TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 Gene3D G3DSA:3.40.50.2300 997 1119 1.5E-17 T 14-10-2018 TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 Pfam PF00072 Response regulator receiver domain 1001 1112 7.5E-12 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 SMART SM00387 867 978 1.7E-28 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 SMART SM00086 696 738 0.0013 T 14-10-2018 IPR001610 PAC motif TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 SUPERFAMILY SSF158472 310 360 1.16E-7 T 14-10-2018 TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 SUPERFAMILY SSF52172 1001 1117 1.42E-19 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 Gene3D G3DSA:1.10.287.130 733 821 7.0E-16 T 14-10-2018 TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 SUPERFAMILY SSF55785 361 450 4.71E-11 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 868 977 5.5E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 SUPERFAMILY SSF47384 742 823 2.94E-13 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 Pfam PF08448 PAS fold 381 478 1.9E-11 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 Pfam PF08448 PAS fold 503 613 4.8E-14 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 Pfam PF13426 PAS domain 640 737 2.7E-11 T 14-10-2018 IPR000014 PAS domain TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 SMART SM00448 998 1112 3.4E-14 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 Pfam PF00672 HAMP domain 310 359 2.4E-6 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 Gene3D G3DSA:3.30.450.20 485 618 6.5E-18 T 14-10-2018 TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 Gene3D G3DSA:3.30.565.10 829 981 9.5E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 Gene3D G3DSA:3.30.450.20 28 170 3.8E-23 T 14-10-2018 TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 Gene3D G3DSA:3.30.450.20 369 476 4.2E-26 T 14-10-2018 TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 Gene3D G3DSA:3.30.450.20 619 732 2.4E-23 T 14-10-2018 TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 SUPERFAMILY SSF55874 812 976 6.02E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 PRINTS PR00344 Bacterial sensor protein C-terminal signature 921 931 3.1E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 PRINTS PR00344 Bacterial sensor protein C-terminal signature 938 956 3.1E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 PRINTS PR00344 Bacterial sensor protein C-terminal signature 903 917 3.1E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 PRINTS PR00344 Bacterial sensor protein C-terminal signature 962 975 3.1E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 SUPERFAMILY SSF55785 489 595 1.24E-8 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 SMART SM00091 623 689 1.2E-11 T 14-10-2018 IPR000014 PAS domain TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 SMART SM00091 496 564 32.0 T 14-10-2018 IPR000014 PAS domain TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 SMART SM00091 373 438 8.9E-8 T 14-10-2018 IPR000014 PAS domain TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 Pfam PF02743 Cache domain 74 260 2.9E-12 T 14-10-2018 IPR033479 Double Cache domain 1 TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 619 745 2.5E-26 T 14-10-2018 IPR000014 PAS domain TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 SMART SM00388 758 823 1.2E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 Pfam PF00512 His Kinase A (phospho-acceptor) domain 758 823 1.3E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 Gene3D G3DSA:1.20.1480.50 277 368 1.6E-7 T 14-10-2018 TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 SMART SM00304 310 363 3.5E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_05350 c9615829a18ad1140c07b1e064009c89 1121 SUPERFAMILY SSF55785 608 736 4.79E-27 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_17075 f8b8391bf991dc1ecd47586e527692f0 485 SUPERFAMILY SSF52540 1 238 2.97E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_17075 f8b8391bf991dc1ecd47586e527692f0 485 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 235 1.9E-17 T 14-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TSH58p_17075 f8b8391bf991dc1ecd47586e527692f0 485 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 5 479 2.3E-138 T 14-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 TSH58p_17075 f8b8391bf991dc1ecd47586e527692f0 485 Gene3D G3DSA:3.40.50.300 2 240 1.8E-51 T 14-10-2018 TSH58p_17075 f8b8391bf991dc1ecd47586e527692f0 485 Gene3D G3DSA:3.40.50.880 258 399 2.7E-15 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_17075 f8b8391bf991dc1ecd47586e527692f0 485 SUPERFAMILY SSF52317 254 444 4.09E-36 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_17075 f8b8391bf991dc1ecd47586e527692f0 485 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 485 204.087 T 14-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 TSH58p_17075 f8b8391bf991dc1ecd47586e527692f0 485 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 253 437 2.2E-59 T 14-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 TSH58p_01195 bbd99649d2c194e58a18ae1f39dab6b1 298 Gene3D G3DSA:3.40.50.720 107 264 9.2E-100 T 14-10-2018 TSH58p_01195 bbd99649d2c194e58a18ae1f39dab6b1 298 Pfam PF09176 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal 19 98 3.4E-34 T 14-10-2018 IPR015259 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal TSH58p_01195 bbd99649d2c194e58a18ae1f39dab6b1 298 SUPERFAMILY SSF53223 5 98 1.27E-33 T 14-10-2018 TSH58p_01195 bbd99649d2c194e58a18ae1f39dab6b1 298 Gene3D G3DSA:3.40.50.10280 6 293 9.2E-100 T 14-10-2018 IPR037089 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal domain superfamily TSH58p_01195 bbd99649d2c194e58a18ae1f39dab6b1 298 SUPERFAMILY SSF51735 113 208 1.57E-8 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_30485 27ecef033493c436d8f2b62596255886 494 Gene3D G3DSA:3.50.50.60 35 382 4.7E-41 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_30485 27ecef033493c436d8f2b62596255886 494 SUPERFAMILY SSF51905 214 377 1.1E-5 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_30485 27ecef033493c436d8f2b62596255886 494 SUPERFAMILY SSF51905 36 259 2.59E-24 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_30485 27ecef033493c436d8f2b62596255886 494 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 38 296 5.1E-13 T 14-10-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase TSH58p_19280 0df541196fc494389ee2082d119bfbaa 211 Pfam PF01081 KDPG and KHG aldolase 12 201 4.4E-61 T 14-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 TSH58p_19280 0df541196fc494389ee2082d119bfbaa 211 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 126 139 - T 14-10-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 TSH58p_19280 0df541196fc494389ee2082d119bfbaa 211 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 38 47 - T 14-10-2018 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 TSH58p_19280 0df541196fc494389ee2082d119bfbaa 211 SUPERFAMILY SSF51569 9 207 2.56E-57 T 14-10-2018 TSH58p_19280 0df541196fc494389ee2082d119bfbaa 211 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 11 207 4.8E-66 T 14-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 TSH58p_19280 0df541196fc494389ee2082d119bfbaa 211 Gene3D G3DSA:3.20.20.70 2 210 3.2E-63 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_04930 e3c5faa9a02cf67bbd39bbb1972621f2 425 Gene3D G3DSA:3.40.50.2000 13 212 1.2E-13 T 14-10-2018 TSH58p_04930 e3c5faa9a02cf67bbd39bbb1972621f2 425 Gene3D G3DSA:3.40.50.2000 213 386 1.8E-16 T 14-10-2018 TSH58p_04930 e3c5faa9a02cf67bbd39bbb1972621f2 425 SUPERFAMILY SSF53756 16 402 1.52E-42 T 14-10-2018 TSH58p_04930 e3c5faa9a02cf67bbd39bbb1972621f2 425 Pfam PF13579 Glycosyl transferase 4-like domain 30 203 1.4E-17 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TSH58p_17400 375fec7a01d93a424e144871897a0007 570 Gene3D G3DSA:3.40.50.300 2 135 1.4E-6 T 14-10-2018 TSH58p_17400 375fec7a01d93a424e144871897a0007 570 SUPERFAMILY SSF52540 5 359 4.17E-5 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_02950 8027db8a2ef00d794fa8ee057e6d5e22 409 Gene3D G3DSA:1.20.1250.20 205 392 1.5E-14 T 14-10-2018 TSH58p_02950 8027db8a2ef00d794fa8ee057e6d5e22 409 Gene3D G3DSA:1.20.1250.20 2 184 8.8E-19 T 14-10-2018 TSH58p_02950 8027db8a2ef00d794fa8ee057e6d5e22 409 Pfam PF07690 Major Facilitator Superfamily 14 356 3.3E-31 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_02950 8027db8a2ef00d794fa8ee057e6d5e22 409 SUPERFAMILY SSF103473 5 392 3.01E-43 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_16700 b31306dd10eb0f328e7cd6880d7074f7 716 Gene3D G3DSA:2.60.40.10 3 149 5.0E-52 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_16700 b31306dd10eb0f328e7cd6880d7074f7 716 SUPERFAMILY SSF81296 13 160 5.88E-49 T 14-10-2018 IPR014756 Immunoglobulin E-set TSH58p_16700 b31306dd10eb0f328e7cd6880d7074f7 716 SUPERFAMILY SSF51011 599 709 1.11E-22 T 14-10-2018 TSH58p_16700 b31306dd10eb0f328e7cd6880d7074f7 716 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 14 709 0.0 T 14-10-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 TSH58p_16700 b31306dd10eb0f328e7cd6880d7074f7 716 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 18 106 3.9E-20 T 14-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 TSH58p_16700 b31306dd10eb0f328e7cd6880d7074f7 716 Gene3D G3DSA:3.20.20.80 150 592 9.4E-183 T 14-10-2018 TSH58p_16700 b31306dd10eb0f328e7cd6880d7074f7 716 Pfam PF00128 Alpha amylase, catalytic domain 201 285 6.8E-10 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSH58p_16700 b31306dd10eb0f328e7cd6880d7074f7 716 SMART SM00642 171 578 1.5E-8 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSH58p_16700 b31306dd10eb0f328e7cd6880d7074f7 716 SUPERFAMILY SSF51445 148 586 3.01E-142 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_16700 b31306dd10eb0f328e7cd6880d7074f7 716 Gene3D G3DSA:2.60.40.1180 598 710 1.3E-16 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta TSH58p_08870 9ad15415ddc7d4cca6545fece992bd73 447 SUPERFAMILY SSF48163 283 442 7.46E-30 T 14-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TSH58p_08870 9ad15415ddc7d4cca6545fece992bd73 447 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 2 446 26.401 T 14-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TSH58p_08870 9ad15415ddc7d4cca6545fece992bd73 447 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 9 20 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_08870 9ad15415ddc7d4cca6545fece992bd73 447 Gene3D G3DSA:1.10.10.350 358 445 1.5E-16 T 14-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TSH58p_08870 9ad15415ddc7d4cca6545fece992bd73 447 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 9.0E-24 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSH58p_08870 9ad15415ddc7d4cca6545fece992bd73 447 PRINTS PR00987 Glutamyl-tRNA synthetase signature 182 192 9.0E-24 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSH58p_08870 9ad15415ddc7d4cca6545fece992bd73 447 PRINTS PR00987 Glutamyl-tRNA synthetase signature 20 31 9.0E-24 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSH58p_08870 9ad15415ddc7d4cca6545fece992bd73 447 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 9.0E-24 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSH58p_08870 9ad15415ddc7d4cca6545fece992bd73 447 PRINTS PR00987 Glutamyl-tRNA synthetase signature 198 206 9.0E-24 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSH58p_08870 9ad15415ddc7d4cca6545fece992bd73 447 Gene3D G3DSA:3.40.50.620 1 317 7.2E-103 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_08870 9ad15415ddc7d4cca6545fece992bd73 447 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 3 307 4.1E-74 T 14-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 TSH58p_08870 9ad15415ddc7d4cca6545fece992bd73 447 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 3 327 2.0E-94 T 14-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TSH58p_08870 9ad15415ddc7d4cca6545fece992bd73 447 SUPERFAMILY SSF52374 3 299 5.9E-90 T 14-10-2018 TSH58p_13025 dd9a575e8083cdebcf219eac741a00c4 481 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 325 467 6.3E-16 T 14-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain TSH58p_13025 dd9a575e8083cdebcf219eac741a00c4 481 Pfam PF01943 Polysaccharide biosynthesis protein 11 271 1.9E-29 T 14-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 TSH58p_19865 1ea2dbed2c3a5b5fdc7bd456b0c18c34 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 65 3.3E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_19865 1ea2dbed2c3a5b5fdc7bd456b0c18c34 310 Pfam PF03466 LysR substrate binding domain 91 296 1.3E-45 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_19865 1ea2dbed2c3a5b5fdc7bd456b0c18c34 310 Gene3D G3DSA:3.40.190.10 166 268 4.2E-66 T 14-10-2018 TSH58p_19865 1ea2dbed2c3a5b5fdc7bd456b0c18c34 310 SUPERFAMILY SSF46785 5 115 4.34E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_19865 1ea2dbed2c3a5b5fdc7bd456b0c18c34 310 Gene3D G3DSA:1.10.10.10 6 94 8.5E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_19865 1ea2dbed2c3a5b5fdc7bd456b0c18c34 310 SUPERFAMILY SSF53850 93 301 9.41E-48 T 14-10-2018 TSH58p_19865 1ea2dbed2c3a5b5fdc7bd456b0c18c34 310 Gene3D G3DSA:3.40.190.10 95 294 4.2E-66 T 14-10-2018 TSH58p_25835 4ecee9c42c82b2ee30703071ebb0e2f7 266 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 264 17.148 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 TSH58p_25835 4ecee9c42c82b2ee30703071ebb0e2f7 266 Pfam PF02673 Bacitracin resistance protein BacA 9 257 6.3E-79 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 TSH58p_25835 4ecee9c42c82b2ee30703071ebb0e2f7 266 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 9 257 1.4E-71 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 TSH58p_21095 48f2e94f93a9f81d7a0cb31bcd7f61b2 353 SUPERFAMILY SSF50331 237 346 7.14E-14 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSH58p_21095 48f2e94f93a9f81d7a0cb31bcd7f61b2 353 Pfam PF00005 ABC transporter 20 161 3.8E-36 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_21095 48f2e94f93a9f81d7a0cb31bcd7f61b2 353 Pfam PF08402 TOBE domain 270 345 7.9E-12 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TSH58p_21095 48f2e94f93a9f81d7a0cb31bcd7f61b2 353 Gene3D G3DSA:2.40.50.940 223 343 6.1E-12 T 14-10-2018 TSH58p_21095 48f2e94f93a9f81d7a0cb31bcd7f61b2 353 SUPERFAMILY SSF52540 4 242 7.78E-86 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_21095 48f2e94f93a9f81d7a0cb31bcd7f61b2 353 SMART SM00382 28 211 2.8E-21 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_21095 48f2e94f93a9f81d7a0cb31bcd7f61b2 353 Gene3D G3DSA:3.40.50.300 3 222 2.2E-69 T 14-10-2018 TSH58p_21095 48f2e94f93a9f81d7a0cb31bcd7f61b2 353 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_21095 48f2e94f93a9f81d7a0cb31bcd7f61b2 353 Gene3D G3DSA:2.40.50.140 277 337 6.1E-12 T 14-10-2018 TSH58p_15120 ef05a61229bf4d44e0e79463203e8b77 124 SUPERFAMILY SSF48300 3 60 8.24E-16 T 14-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_15120 ef05a61229bf4d44e0e79463203e8b77 124 SUPERFAMILY SSF54736 53 124 3.49E-26 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like TSH58p_15120 ef05a61229bf4d44e0e79463203e8b77 124 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 124 1.6E-48 T 14-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_15120 ef05a61229bf4d44e0e79463203e8b77 124 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 58 124 5.2E-32 T 14-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_15120 ef05a61229bf4d44e0e79463203e8b77 124 Gene3D G3DSA:3.30.1390.10 54 124 6.3E-33 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like TSH58p_15120 ef05a61229bf4d44e0e79463203e8b77 124 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 50 3.7E-19 T 14-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_15120 ef05a61229bf4d44e0e79463203e8b77 124 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 1 124 24.958 T 14-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_15120 ef05a61229bf4d44e0e79463203e8b77 124 Gene3D G3DSA:1.20.5.710 3 53 4.2E-17 T 14-10-2018 TSH58p_15120 ef05a61229bf4d44e0e79463203e8b77 124 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 60 124 1.0E-23 T 14-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_27100 8dcdef8d8c0a2405b917211f62b30256 332 Gene3D G3DSA:3.60.15.10 59 330 9.4E-90 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_27100 8dcdef8d8c0a2405b917211f62b30256 332 SUPERFAMILY SSF56281 70 295 4.72E-35 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_27100 8dcdef8d8c0a2405b917211f62b30256 332 PIRSF PIRSF038896 4 30 47.0 T 14-10-2018 IPR024884 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D GO:0008270|GO:0070290 Reactome: R-HSA-2466712 TSH58p_27100 8dcdef8d8c0a2405b917211f62b30256 332 PIRSF PIRSF038896 21 330 1.3E-108 T 14-10-2018 IPR024884 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D GO:0008270|GO:0070290 Reactome: R-HSA-2466712 TSH58p_27100 8dcdef8d8c0a2405b917211f62b30256 332 Pfam PF12706 Beta-lactamase superfamily domain 88 285 5.8E-46 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_27100 8dcdef8d8c0a2405b917211f62b30256 332 SMART SM00849 75 284 0.0077 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_27250 42735ff426903b78d631357f02bcf33b 160 Pfam PF00258 Flavodoxin 5 155 6.9E-24 T 14-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 TSH58p_27250 42735ff426903b78d631357f02bcf33b 160 Gene3D G3DSA:3.40.50.360 1 160 6.6E-43 T 14-10-2018 IPR029039 Flavoprotein-like superfamily TSH58p_27250 42735ff426903b78d631357f02bcf33b 160 ProSitePatterns PS00201 Flavodoxin signature. 5 21 - T 14-10-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 TSH58p_27250 42735ff426903b78d631357f02bcf33b 160 SUPERFAMILY SSF52218 1 160 2.62E-42 T 14-10-2018 IPR029039 Flavoprotein-like superfamily TSH58p_27250 42735ff426903b78d631357f02bcf33b 160 PRINTS PR00369 Flavodoxin signature 47 58 8.8E-5 T 14-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 TSH58p_27250 42735ff426903b78d631357f02bcf33b 160 PRINTS PR00369 Flavodoxin signature 76 86 8.8E-5 T 14-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 TSH58p_27250 42735ff426903b78d631357f02bcf33b 160 PRINTS PR00369 Flavodoxin signature 4 17 8.8E-5 T 14-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 TSH58p_27250 42735ff426903b78d631357f02bcf33b 160 TIGRFAM TIGR01752 flav_long: flavodoxin 3 159 3.8E-57 T 14-10-2018 IPR010086 Flavodoxin, long chain GO:0010181 TSH58p_27250 42735ff426903b78d631357f02bcf33b 160 PIRSF PIRSF038996 1 160 1.3E-58 T 14-10-2018 IPR010086 Flavodoxin, long chain GO:0010181 TSH58p_18915 669f511967bb7f3372fe7e40ee6ea4f8 75 Pfam PF06568 Domain of unknown function (DUF1127) 22 59 4.5E-7 T 14-10-2018 IPR009506 Protein of unknown function DUF1127 TSH58p_25095 7344a1b15d97be018038a27f9d5f11a9 642 Pfam PF13844 Glycosyl transferase family 41 426 621 5.9E-46 T 14-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 TSH58p_25095 7344a1b15d97be018038a27f9d5f11a9 642 Pfam PF13844 Glycosyl transferase family 41 267 420 2.3E-32 T 14-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 TSH58p_25095 7344a1b15d97be018038a27f9d5f11a9 642 SUPERFAMILY SSF48452 15 183 2.6E-20 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25095 7344a1b15d97be018038a27f9d5f11a9 642 Gene3D G3DSA:3.40.50.11380 260 610 1.6E-145 T 14-10-2018 TSH58p_25095 7344a1b15d97be018038a27f9d5f11a9 642 Pfam PF13428 Tetratricopeptide repeat 119 153 3.5E-6 T 14-10-2018 TSH58p_25095 7344a1b15d97be018038a27f9d5f11a9 642 Gene3D G3DSA:3.40.50.2000 424 603 1.6E-145 T 14-10-2018 TSH58p_25095 7344a1b15d97be018038a27f9d5f11a9 642 Gene3D G3DSA:1.25.40.10 8 116 1.1E-13 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25095 7344a1b15d97be018038a27f9d5f11a9 642 Gene3D G3DSA:1.25.40.10 117 217 5.6E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25095 7344a1b15d97be018038a27f9d5f11a9 642 SUPERFAMILY SSF53756 397 618 3.01E-7 T 14-10-2018 TSH58p_26275 cdc02b0940305885a48710fff03002e3 113 SUPERFAMILY SSF55594 28 113 9.03E-27 T 14-10-2018 IPR035895 HPr-like superfamily TSH58p_26275 cdc02b0940305885a48710fff03002e3 113 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 38 45 - T 14-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site TSH58p_26275 cdc02b0940305885a48710fff03002e3 113 PRINTS PR00107 Phosphocarrier protein signature 38 54 5.0E-9 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like TSH58p_26275 cdc02b0940305885a48710fff03002e3 113 PRINTS PR00107 Phosphocarrier protein signature 78 95 5.0E-9 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like TSH58p_26275 cdc02b0940305885a48710fff03002e3 113 PRINTS PR00107 Phosphocarrier protein signature 63 78 5.0E-9 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like TSH58p_26275 cdc02b0940305885a48710fff03002e3 113 Gene3D G3DSA:3.30.1340.10 26 107 1.0E-28 T 14-10-2018 IPR035895 HPr-like superfamily TSH58p_26275 cdc02b0940305885a48710fff03002e3 113 Pfam PF00381 PTS HPr component phosphorylation site 29 107 3.5E-26 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like TSH58p_26275 cdc02b0940305885a48710fff03002e3 113 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 29 106 1.2E-26 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like TSH58p_19510 83d46918c49ad60a54b1776b1addb2fd 254 Pfam PF00005 ABC transporter 37 182 1.2E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_19510 83d46918c49ad60a54b1776b1addb2fd 254 Gene3D G3DSA:3.40.50.300 17 254 1.2E-65 T 14-10-2018 TSH58p_19510 83d46918c49ad60a54b1776b1addb2fd 254 SMART SM00382 46 233 6.7E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_19510 83d46918c49ad60a54b1776b1addb2fd 254 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_19510 83d46918c49ad60a54b1776b1addb2fd 254 SUPERFAMILY SSF52540 19 252 4.05E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_09440 112e1e6ab5f095934251f1446c77192a 974 Pfam PF02779 Transketolase, pyrimidine binding domain 625 820 1.6E-64 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSH58p_09440 112e1e6ab5f095934251f1446c77192a 974 Gene3D G3DSA:1.10.287.1150 113 193 4.3E-23 T 14-10-2018 TSH58p_09440 112e1e6ab5f095934251f1446c77192a 974 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 112 971 0.0 T 14-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 TSH58p_09440 112e1e6ab5f095934251f1446c77192a 974 Gene3D G3DSA:3.40.50.12470 589 836 8.1E-171 T 14-10-2018 TSH58p_09440 112e1e6ab5f095934251f1446c77192a 974 Pfam PF00676 Dehydrogenase E1 component 239 556 8.1E-58 T 14-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 TSH58p_09440 112e1e6ab5f095934251f1446c77192a 974 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 823 971 2.6E-56 T 14-10-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 TSH58p_09440 112e1e6ab5f095934251f1446c77192a 974 Gene3D G3DSA:3.40.50.11610 756 968 8.1E-171 T 14-10-2018 TSH58p_09440 112e1e6ab5f095934251f1446c77192a 974 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 8 47 1.6E-17 T 14-10-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 TSH58p_09440 112e1e6ab5f095934251f1446c77192a 974 SUPERFAMILY SSF52518 148 572 4.12E-92 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_09440 112e1e6ab5f095934251f1446c77192a 974 SUPERFAMILY SSF52518 609 826 2.26E-49 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_09440 112e1e6ab5f095934251f1446c77192a 974 PIRSF PIRSF000157 1 973 0.0 T 14-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 TSH58p_09440 112e1e6ab5f095934251f1446c77192a 974 SMART SM00861 626 819 6.0E-62 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSH58p_09440 112e1e6ab5f095934251f1446c77192a 974 Gene3D G3DSA:3.40.50.970 194 561 2.6E-155 T 14-10-2018 TSH58p_23395 96b86b1b00d442cf7416763d173f6123 225 Gene3D G3DSA:3.90.930.1 13 136 1.6E-8 T 14-10-2018 TSH58p_23395 96b86b1b00d442cf7416763d173f6123 225 Gene3D G3DSA:2.20.110.10 148 220 3.9E-8 T 14-10-2018 TSH58p_23395 96b86b1b00d442cf7416763d173f6123 225 SUPERFAMILY SSF82185 20 91 3.27E-10 T 14-10-2018 TSH58p_23395 96b86b1b00d442cf7416763d173f6123 225 SUPERFAMILY SSF82185 99 216 2.75E-20 T 14-10-2018 TSH58p_24490 ae895b911a01cfb9b9aced79625247c1 538 Pfam PF00501 AMP-binding enzyme 31 440 1.6E-90 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_24490 ae895b911a01cfb9b9aced79625247c1 538 Gene3D G3DSA:3.30.300.30 438 538 1.6E-30 T 14-10-2018 TSH58p_24490 ae895b911a01cfb9b9aced79625247c1 538 Gene3D G3DSA:3.40.50.12780 15 437 7.7E-121 T 14-10-2018 TSH58p_24490 ae895b911a01cfb9b9aced79625247c1 538 ProSitePatterns PS00455 Putative AMP-binding domain signature. 190 201 - T 14-10-2018 IPR020845 AMP-binding, conserved site TSH58p_24490 ae895b911a01cfb9b9aced79625247c1 538 Pfam PF13193 AMP-binding enzyme C-terminal domain 450 528 3.2E-22 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSH58p_24490 ae895b911a01cfb9b9aced79625247c1 538 SUPERFAMILY SSF56801 13 537 1.44E-153 T 14-10-2018 TSH58p_10230 3ae822c2442850ef6312223a9a71ff3f 234 Gene3D G3DSA:1.20.144.10 94 201 1.7E-15 T 14-10-2018 TSH58p_10230 3ae822c2442850ef6312223a9a71ff3f 234 SUPERFAMILY SSF48317 3 191 3.53E-22 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily TSH58p_10230 3ae822c2442850ef6312223a9a71ff3f 234 Pfam PF01569 PAP2 superfamily 67 181 3.3E-15 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase TSH58p_10230 3ae822c2442850ef6312223a9a71ff3f 234 SMART SM00014 63 179 6.6E-12 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase TSH58p_29935 b46cd45cbcfceb9ef48a88949ee35478 773 Pfam PF00512 His Kinase A (phospho-acceptor) domain 516 581 2.2E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_29935 b46cd45cbcfceb9ef48a88949ee35478 773 PIRSF PIRSF037532 13 746 2.9E-266 T 14-10-2018 IPR017232 Signal transduction histidine kinase, nitrogen fixation and metabolism regulator TSH58p_29935 b46cd45cbcfceb9ef48a88949ee35478 773 SMART SM00387 625 742 1.6E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_29935 b46cd45cbcfceb9ef48a88949ee35478 773 Gene3D G3DSA:1.20.1480.50 291 384 1.2E-11 T 14-10-2018 TSH58p_29935 b46cd45cbcfceb9ef48a88949ee35478 773 Gene3D G3DSA:3.30.450.20 385 502 8.2E-14 T 14-10-2018 TSH58p_29935 b46cd45cbcfceb9ef48a88949ee35478 773 Gene3D G3DSA:3.30.565.10 585 747 9.3E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_29935 b46cd45cbcfceb9ef48a88949ee35478 773 PRINTS PR00344 Bacterial sensor protein C-terminal signature 702 720 6.9E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_29935 b46cd45cbcfceb9ef48a88949ee35478 773 PRINTS PR00344 Bacterial sensor protein C-terminal signature 673 687 6.9E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_29935 b46cd45cbcfceb9ef48a88949ee35478 773 PRINTS PR00344 Bacterial sensor protein C-terminal signature 726 739 6.9E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_29935 b46cd45cbcfceb9ef48a88949ee35478 773 PRINTS PR00344 Bacterial sensor protein C-terminal signature 691 701 6.9E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_29935 b46cd45cbcfceb9ef48a88949ee35478 773 SMART SM00388 513 584 3.1E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_29935 b46cd45cbcfceb9ef48a88949ee35478 773 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 626 740 1.3E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_29935 b46cd45cbcfceb9ef48a88949ee35478 773 Pfam PF00989 PAS fold 402 502 6.4E-5 T 14-10-2018 IPR013767 PAS fold GO:0006355 TSH58p_29935 b46cd45cbcfceb9ef48a88949ee35478 773 Pfam PF00672 HAMP domain 328 376 1.7E-11 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_29935 b46cd45cbcfceb9ef48a88949ee35478 773 SUPERFAMILY SSF47384 509 582 1.18E-10 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_29935 b46cd45cbcfceb9ef48a88949ee35478 773 Gene3D G3DSA:1.10.287.130 503 581 6.8E-11 T 14-10-2018 TSH58p_29935 b46cd45cbcfceb9ef48a88949ee35478 773 SUPERFAMILY SSF55785 381 503 2.09E-10 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_29935 b46cd45cbcfceb9ef48a88949ee35478 773 SUPERFAMILY SSF158472 328 377 2.75E-10 T 14-10-2018 TSH58p_29935 b46cd45cbcfceb9ef48a88949ee35478 773 SMART SM00304 327 380 1.7E-13 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_29935 b46cd45cbcfceb9ef48a88949ee35478 773 SUPERFAMILY SSF55874 575 741 1.02E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_21505 b46cd45cbcfceb9ef48a88949ee35478 773 Pfam PF00512 His Kinase A (phospho-acceptor) domain 516 581 2.2E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_21505 b46cd45cbcfceb9ef48a88949ee35478 773 PIRSF PIRSF037532 13 746 2.9E-266 T 14-10-2018 IPR017232 Signal transduction histidine kinase, nitrogen fixation and metabolism regulator TSH58p_21505 b46cd45cbcfceb9ef48a88949ee35478 773 SMART SM00387 625 742 1.6E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_21505 b46cd45cbcfceb9ef48a88949ee35478 773 Gene3D G3DSA:1.20.1480.50 291 384 1.2E-11 T 14-10-2018 TSH58p_21505 b46cd45cbcfceb9ef48a88949ee35478 773 Gene3D G3DSA:3.30.450.20 385 502 8.2E-14 T 14-10-2018 TSH58p_21505 b46cd45cbcfceb9ef48a88949ee35478 773 Gene3D G3DSA:3.30.565.10 585 747 9.3E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_21505 b46cd45cbcfceb9ef48a88949ee35478 773 PRINTS PR00344 Bacterial sensor protein C-terminal signature 702 720 6.9E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_21505 b46cd45cbcfceb9ef48a88949ee35478 773 PRINTS PR00344 Bacterial sensor protein C-terminal signature 673 687 6.9E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_21505 b46cd45cbcfceb9ef48a88949ee35478 773 PRINTS PR00344 Bacterial sensor protein C-terminal signature 726 739 6.9E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_21505 b46cd45cbcfceb9ef48a88949ee35478 773 PRINTS PR00344 Bacterial sensor protein C-terminal signature 691 701 6.9E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_21505 b46cd45cbcfceb9ef48a88949ee35478 773 SMART SM00388 513 584 3.1E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_21505 b46cd45cbcfceb9ef48a88949ee35478 773 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 626 740 1.3E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_21505 b46cd45cbcfceb9ef48a88949ee35478 773 Pfam PF00989 PAS fold 402 502 6.4E-5 T 14-10-2018 IPR013767 PAS fold GO:0006355 TSH58p_21505 b46cd45cbcfceb9ef48a88949ee35478 773 Pfam PF00672 HAMP domain 328 376 1.7E-11 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_21505 b46cd45cbcfceb9ef48a88949ee35478 773 SUPERFAMILY SSF47384 509 582 1.18E-10 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_21505 b46cd45cbcfceb9ef48a88949ee35478 773 Gene3D G3DSA:1.10.287.130 503 581 6.8E-11 T 14-10-2018 TSH58p_21505 b46cd45cbcfceb9ef48a88949ee35478 773 SUPERFAMILY SSF55785 381 503 2.09E-10 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_21505 b46cd45cbcfceb9ef48a88949ee35478 773 SUPERFAMILY SSF158472 328 377 2.75E-10 T 14-10-2018 TSH58p_21505 b46cd45cbcfceb9ef48a88949ee35478 773 SMART SM00304 327 380 1.7E-13 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_21505 b46cd45cbcfceb9ef48a88949ee35478 773 SUPERFAMILY SSF55874 575 741 1.02E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_07460 0df470fb1fe5151d3f6978f7cc5faab7 599 SUPERFAMILY SSF47203 282 460 2.58E-47 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TSH58p_07460 0df470fb1fe5151d3f6978f7cc5faab7 599 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 466 594 1.6E-27 T 14-10-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain TSH58p_07460 0df470fb1fe5151d3f6978f7cc5faab7 599 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 4 28 1.5E-7 T 14-10-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria TSH58p_07460 0df470fb1fe5151d3f6978f7cc5faab7 599 Gene3D G3DSA:1.20.140.10 289 453 5.6E-51 T 14-10-2018 TSH58p_07460 0df470fb1fe5151d3f6978f7cc5faab7 599 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 271 2.5E-17 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TSH58p_07460 0df470fb1fe5151d3f6978f7cc5faab7 599 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 40 157 5.8E-11 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TSH58p_07460 0df470fb1fe5151d3f6978f7cc5faab7 599 Gene3D G3DSA:2.40.110.10 160 288 6.0E-27 T 14-10-2018 TSH58p_07460 0df470fb1fe5151d3f6978f7cc5faab7 599 SUPERFAMILY SSF56645 38 272 2.69E-58 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TSH58p_07460 0df470fb1fe5151d3f6978f7cc5faab7 599 Gene3D G3DSA:1.10.540.10 38 158 1.7E-15 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TSH58p_07460 0df470fb1fe5151d3f6978f7cc5faab7 599 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 284 450 2.2E-28 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TSH58p_29010 33cf51ddcae592ad340d2fad9436e88b 334 Gene3D G3DSA:3.40.50.720 105 302 4.5E-90 T 14-10-2018 TSH58p_29010 33cf51ddcae592ad340d2fad9436e88b 334 SUPERFAMILY SSF52283 19 133 9.64E-24 T 14-10-2018 TSH58p_29010 33cf51ddcae592ad340d2fad9436e88b 334 Gene3D G3DSA:3.40.50.720 25 325 4.5E-90 T 14-10-2018 TSH58p_29010 33cf51ddcae592ad340d2fad9436e88b 334 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 24 332 1.4E-22 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 TSH58p_29010 33cf51ddcae592ad340d2fad9436e88b 334 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 202 224 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TSH58p_29010 33cf51ddcae592ad340d2fad9436e88b 334 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 153 180 - T 14-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 TSH58p_29010 33cf51ddcae592ad340d2fad9436e88b 334 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 113 301 3.1E-45 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TSH58p_29010 33cf51ddcae592ad340d2fad9436e88b 334 SUPERFAMILY SSF51735 107 301 4.94E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_03820 39d2ed7ec740d6b2faa7b6b7aace8bd5 250 Gene3D G3DSA:1.10.3720.10 49 246 3.6E-17 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_03820 39d2ed7ec740d6b2faa7b6b7aace8bd5 250 SUPERFAMILY SSF161098 54 233 1.44E-23 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_03820 39d2ed7ec740d6b2faa7b6b7aace8bd5 250 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 243 8.6E-13 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_08745 c174061054858d4dfdf4b48e8afeeaf0 726 Pfam PF02769 AIR synthase related protein, C-terminal domain 191 343 1.6E-34 T 14-10-2018 IPR010918 PurM-like, C-terminal domain TSH58p_08745 c174061054858d4dfdf4b48e8afeeaf0 726 Pfam PF02769 AIR synthase related protein, C-terminal domain 561 694 3.9E-20 T 14-10-2018 IPR010918 PurM-like, C-terminal domain TSH58p_08745 c174061054858d4dfdf4b48e8afeeaf0 726 Gene3D G3DSA:3.30.1330.10 33 181 4.2E-132 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSH58p_08745 c174061054858d4dfdf4b48e8afeeaf0 726 Gene3D G3DSA:3.30.1330.10 376 550 3.0E-56 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSH58p_08745 c174061054858d4dfdf4b48e8afeeaf0 726 Gene3D G3DSA:3.90.650.10 555 721 1.4E-39 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSH58p_08745 c174061054858d4dfdf4b48e8afeeaf0 726 Pfam PF00586 AIR synthase related protein, N-terminal domain 76 177 1.7E-23 T 14-10-2018 IPR016188 PurM-like, N-terminal domain TSH58p_08745 c174061054858d4dfdf4b48e8afeeaf0 726 Pfam PF00586 AIR synthase related protein, N-terminal domain 430 546 1.8E-23 T 14-10-2018 IPR016188 PurM-like, N-terminal domain TSH58p_08745 c174061054858d4dfdf4b48e8afeeaf0 726 PIRSF PIRSF001587 1 724 2.3E-286 T 14-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSH58p_08745 c174061054858d4dfdf4b48e8afeeaf0 726 SUPERFAMILY SSF55326 4 185 1.35E-50 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSH58p_08745 c174061054858d4dfdf4b48e8afeeaf0 726 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 726 321.261 T 14-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSH58p_08745 c174061054858d4dfdf4b48e8afeeaf0 726 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 7 717 1.1E-282 T 14-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSH58p_08745 c174061054858d4dfdf4b48e8afeeaf0 726 SUPERFAMILY SSF56042 558 696 1.02E-36 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSH58p_08745 c174061054858d4dfdf4b48e8afeeaf0 726 SUPERFAMILY SSF55326 389 550 5.5E-52 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSH58p_08745 c174061054858d4dfdf4b48e8afeeaf0 726 Gene3D G3DSA:3.90.650.10 18 344 4.2E-132 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSH58p_08745 c174061054858d4dfdf4b48e8afeeaf0 726 SUPERFAMILY SSF56042 188 414 1.41E-56 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSH58p_20495 41f31bae9b825042c1a8ee90ab84ecd1 687 Pfam PF00990 Diguanylate cyclase, GGDEF domain 256 409 4.9E-45 T 14-10-2018 IPR000160 GGDEF domain TSH58p_20495 41f31bae9b825042c1a8ee90ab84ecd1 687 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 254 411 1.1E-37 T 14-10-2018 IPR000160 GGDEF domain TSH58p_20495 41f31bae9b825042c1a8ee90ab84ecd1 687 SUPERFAMILY SSF55073 261 418 3.92E-49 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_20495 41f31bae9b825042c1a8ee90ab84ecd1 687 SMART SM00091 131 197 6.6E-6 T 14-10-2018 IPR000014 PAS domain TSH58p_20495 41f31bae9b825042c1a8ee90ab84ecd1 687 SMART SM00091 7 74 1.8E-4 T 14-10-2018 IPR000014 PAS domain TSH58p_20495 41f31bae9b825042c1a8ee90ab84ecd1 687 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 133 250 2.9E-13 T 14-10-2018 IPR000014 PAS domain TSH58p_20495 41f31bae9b825042c1a8ee90ab84ecd1 687 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 3 129 3.5E-22 T 14-10-2018 IPR000014 PAS domain TSH58p_20495 41f31bae9b825042c1a8ee90ab84ecd1 687 Gene3D G3DSA:3.30.70.270 254 428 7.7E-59 T 14-10-2018 TSH58p_20495 41f31bae9b825042c1a8ee90ab84ecd1 687 SUPERFAMILY SSF55785 12 125 6.46E-21 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_20495 41f31bae9b825042c1a8ee90ab84ecd1 687 SMART SM00052 427 677 2.6E-115 T 14-10-2018 IPR001633 EAL domain TSH58p_20495 41f31bae9b825042c1a8ee90ab84ecd1 687 Pfam PF00563 EAL domain 434 672 9.5E-70 T 14-10-2018 IPR001633 EAL domain TSH58p_20495 41f31bae9b825042c1a8ee90ab84ecd1 687 SUPERFAMILY SSF141868 435 684 4.18E-88 T 14-10-2018 IPR035919 EAL domain superfamily TSH58p_20495 41f31bae9b825042c1a8ee90ab84ecd1 687 Gene3D G3DSA:3.30.450.20 4 132 1.2E-24 T 14-10-2018 TSH58p_20495 41f31bae9b825042c1a8ee90ab84ecd1 687 Gene3D G3DSA:3.30.450.20 133 253 7.2E-24 T 14-10-2018 TSH58p_20495 41f31bae9b825042c1a8ee90ab84ecd1 687 SMART SM00086 81 123 2.8E-6 T 14-10-2018 IPR001610 PAC motif TSH58p_20495 41f31bae9b825042c1a8ee90ab84ecd1 687 SMART SM00086 203 245 5.2 T 14-10-2018 IPR001610 PAC motif TSH58p_20495 41f31bae9b825042c1a8ee90ab84ecd1 687 Pfam PF13426 PAS domain 18 122 4.3E-10 T 14-10-2018 IPR000014 PAS domain TSH58p_20495 41f31bae9b825042c1a8ee90ab84ecd1 687 Gene3D G3DSA:3.20.20.450 429 686 1.2E-100 T 14-10-2018 IPR035919 EAL domain superfamily TSH58p_20495 41f31bae9b825042c1a8ee90ab84ecd1 687 SMART SM00267 245 417 4.0E-58 T 14-10-2018 IPR000160 GGDEF domain TSH58p_20495 41f31bae9b825042c1a8ee90ab84ecd1 687 SUPERFAMILY SSF55785 120 243 5.06E-22 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_20495 41f31bae9b825042c1a8ee90ab84ecd1 687 Pfam PF00989 PAS fold 133 242 3.8E-11 T 14-10-2018 IPR013767 PAS fold GO:0006355 TSH58p_07495 153693117eefc55b4c3bd25d01269292 86 SUPERFAMILY SSF88874 7 64 1.2E-17 T 14-10-2018 TSH58p_07495 153693117eefc55b4c3bd25d01269292 86 Pfam PF07484 Phage Tail Collar Domain 13 65 2.3E-16 T 14-10-2018 IPR011083 Phage tail collar domain TSH58p_07495 153693117eefc55b4c3bd25d01269292 86 Gene3D G3DSA:3.90.1340.10 5 65 1.6E-12 T 14-10-2018 IPR037053 Phage tail collar domain superfamily TSH58p_14410 4f8f5054b79f671b5018d1c04bf27f97 467 Gene3D G3DSA:1.10.45.10 426 465 9.5E-7 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 TSH58p_14410 4f8f5054b79f671b5018d1c04bf27f97 467 Gene3D G3DSA:3.30.465.40 15 239 6.3E-73 T 14-10-2018 TSH58p_14410 4f8f5054b79f671b5018d1c04bf27f97 467 Pfam PF01565 FAD binding domain 51 187 1.7E-39 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TSH58p_14410 4f8f5054b79f671b5018d1c04bf27f97 467 SUPERFAMILY SSF56176 12 225 6.07E-70 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TSH58p_14410 4f8f5054b79f671b5018d1c04bf27f97 467 Gene3D G3DSA:3.30.70.2740 344 425 7.5E-12 T 14-10-2018 TSH58p_14410 4f8f5054b79f671b5018d1c04bf27f97 467 SUPERFAMILY SSF55103 227 465 2.13E-71 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 TSH58p_14410 4f8f5054b79f671b5018d1c04bf27f97 467 Pfam PF02913 FAD linked oxidases, C-terminal domain 225 464 1.4E-63 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 TSH58p_07810 a4c84e33c1cd0bc951c4766970fa0015 292 Gene3D G3DSA:3.40.630.40 3 285 1.5E-100 T 14-10-2018 TSH58p_07810 a4c84e33c1cd0bc951c4766970fa0015 292 SUPERFAMILY SSF53187 13 283 1.38E-86 T 14-10-2018 TSH58p_07810 a4c84e33c1cd0bc951c4766970fa0015 292 Pfam PF05013 N-formylglutamate amidohydrolase 25 256 3.0E-74 T 14-10-2018 IPR007709 N-formylglutamate amidohydrolase TSH58p_15520 3cb3ac9f83d26ca9c3d5bcce5d418d09 167 SUPERFAMILY SSF53335 9 140 9.88E-7 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_15520 3cb3ac9f83d26ca9c3d5bcce5d418d09 167 Pfam PF12692 S-adenosyl-L-methionine methyltransferase 6 142 4.8E-35 T 14-10-2018 IPR025690 Methyltransferase, putative TSH58p_15520 3cb3ac9f83d26ca9c3d5bcce5d418d09 167 Gene3D G3DSA:3.40.50.150 1 167 2.2E-53 T 14-10-2018 TSH58p_09970 09a065f81215e6d362e5a9ca3c7111e7 308 PIRSF PIRSF001438 1 308 1.8E-113 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSH58p_09970 09a065f81215e6d362e5a9ca3c7111e7 308 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 229 298 1.7E-16 T 14-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSH58p_09970 09a065f81215e6d362e5a9ca3c7111e7 308 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 5 215 1.5E-73 T 14-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSH58p_09970 09a065f81215e6d362e5a9ca3c7111e7 308 Gene3D G3DSA:3.30.160.40 225 308 2.3E-23 T 14-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSH58p_09970 09a065f81215e6d362e5a9ca3c7111e7 308 SUPERFAMILY SSF53850 4 222 1.4E-77 T 14-10-2018 TSH58p_09970 09a065f81215e6d362e5a9ca3c7111e7 308 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 4 300 36.389 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSH58p_09970 09a065f81215e6d362e5a9ca3c7111e7 308 Gene3D G3DSA:3.40.190.10 106 205 1.6E-80 T 14-10-2018 TSH58p_09970 09a065f81215e6d362e5a9ca3c7111e7 308 SUPERFAMILY SSF54782 223 306 1.83E-21 T 14-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSH58p_09970 09a065f81215e6d362e5a9ca3c7111e7 308 Gene3D G3DSA:3.40.190.10 5 213 1.6E-80 T 14-10-2018 TSH58p_09970 09a065f81215e6d362e5a9ca3c7111e7 308 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 234 250 - T 14-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSH58p_09970 09a065f81215e6d362e5a9ca3c7111e7 308 PRINTS PR00151 Porphobilinogen deaminase signature 233 250 5.1E-43 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSH58p_09970 09a065f81215e6d362e5a9ca3c7111e7 308 PRINTS PR00151 Porphobilinogen deaminase signature 127 144 5.1E-43 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSH58p_09970 09a065f81215e6d362e5a9ca3c7111e7 308 PRINTS PR00151 Porphobilinogen deaminase signature 48 68 5.1E-43 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSH58p_09970 09a065f81215e6d362e5a9ca3c7111e7 308 PRINTS PR00151 Porphobilinogen deaminase signature 79 98 5.1E-43 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSH58p_09970 09a065f81215e6d362e5a9ca3c7111e7 308 PRINTS PR00151 Porphobilinogen deaminase signature 146 163 5.1E-43 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSH58p_09970 09a065f81215e6d362e5a9ca3c7111e7 308 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 5 297 1.5E-104 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSH58p_16465 04f5816899e0d44edc0b85db2371b47a 321 SUPERFAMILY SSF46565 1 71 6.15E-27 T 14-10-2018 IPR036869 Chaperone J-domain superfamily TSH58p_16465 04f5816899e0d44edc0b85db2371b47a 321 SUPERFAMILY SSF49493 217 295 1.83E-20 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TSH58p_16465 04f5816899e0d44edc0b85db2371b47a 321 SUPERFAMILY SSF49493 141 221 1.57E-19 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TSH58p_16465 04f5816899e0d44edc0b85db2371b47a 321 Gene3D G3DSA:2.60.260.20 142 211 7.2E-17 T 14-10-2018 TSH58p_16465 04f5816899e0d44edc0b85db2371b47a 321 Gene3D G3DSA:1.10.287.110 1 129 8.0E-27 T 14-10-2018 IPR036869 Chaperone J-domain superfamily TSH58p_16465 04f5816899e0d44edc0b85db2371b47a 321 SMART SM00271 2 60 1.6E-27 T 14-10-2018 IPR001623 DnaJ domain TSH58p_16465 04f5816899e0d44edc0b85db2371b47a 321 Pfam PF01556 DnaJ C terminal domain 147 292 1.2E-34 T 14-10-2018 IPR002939 Chaperone DnaJ, C-terminal TSH58p_16465 04f5816899e0d44edc0b85db2371b47a 321 Pfam PF00226 DnaJ domain 3 65 1.3E-23 T 14-10-2018 IPR001623 DnaJ domain TSH58p_16465 04f5816899e0d44edc0b85db2371b47a 321 Gene3D G3DSA:2.60.260.20 213 292 2.0E-29 T 14-10-2018 TSH58p_16465 04f5816899e0d44edc0b85db2371b47a 321 PRINTS PR00625 DnaJ domain signature 5 23 3.1E-19 T 14-10-2018 IPR001623 DnaJ domain TSH58p_16465 04f5816899e0d44edc0b85db2371b47a 321 PRINTS PR00625 DnaJ domain signature 40 60 3.1E-19 T 14-10-2018 IPR001623 DnaJ domain TSH58p_16465 04f5816899e0d44edc0b85db2371b47a 321 PRINTS PR00625 DnaJ domain signature 23 38 3.1E-19 T 14-10-2018 IPR001623 DnaJ domain TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Gene3D G3DSA:2.150.10.10 2532 2574 3.7E-12 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Gene3D G3DSA:2.150.10.10 2421 2493 6.3E-6 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Gene3D G3DSA:2.150.10.10 2575 2623 8.1E-8 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Pfam PF13753 Putative flagellar system-associated repeat 309 386 1.0E-22 T 14-10-2018 IPR028059 Putative flagellar system-associated repeat TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Pfam PF13753 Putative flagellar system-associated repeat 707 784 2.1E-26 T 14-10-2018 IPR028059 Putative flagellar system-associated repeat TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Pfam PF13753 Putative flagellar system-associated repeat 195 276 2.0E-5 T 14-10-2018 IPR028059 Putative flagellar system-associated repeat TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Gene3D G3DSA:2.60.40.10 1754 1840 2.7E-13 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Gene3D G3DSA:2.60.40.10 1371 1458 3.3E-11 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Gene3D G3DSA:2.150.10.10 2624 2732 2.4E-20 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Gene3D G3DSA:2.150.10.10 2494 2531 1.5E-7 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 2513 2531 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 SUPERFAMILY SSF51120 2448 2611 1.78E-25 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Pfam PF12245 Bacterial Ig-like domain (group 3) 1925 1944 3.6 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Pfam PF12245 Bacterial Ig-like domain (group 3) 1637 1657 3.6 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Pfam PF12245 Bacterial Ig-like domain (group 3) 1541 1561 1.6 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Pfam PF12245 Bacterial Ig-like domain (group 3) 2117 2136 1.8 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Pfam PF12245 Bacterial Ig-like domain (group 3) 1732 1752 3.6 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 2648 2666 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 2522 2540 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 PRINTS PR00313 NodO calcium binding signature 2616 2624 3.0E-9 T 14-10-2018 TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 PRINTS PR00313 NodO calcium binding signature 2634 2642 3.0E-9 T 14-10-2018 TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 PRINTS PR00313 NodO calcium binding signature 2559 2570 3.0E-9 T 14-10-2018 TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 PRINTS PR00313 NodO calcium binding signature 2643 2652 3.0E-9 T 14-10-2018 TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 TIGRFAM TIGR02059 swm_rep_I: cyanobacterial long protein repeat 315 388 2.5E-16 T 14-10-2018 IPR011801 Cyanobacterial long protein repeat TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 TIGRFAM TIGR02059 swm_rep_I: cyanobacterial long protein repeat 714 786 7.5E-18 T 14-10-2018 IPR011801 Cyanobacterial long protein repeat TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 SUPERFAMILY SSF51120 2553 2727 7.06E-35 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2652 2668 0.1 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2562 2578 9.2E-4 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2508 2524 0.0016 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2543 2560 0.011 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2492 2505 0.087 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2633 2650 0.0015 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2616 2632 0.011 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2579 2595 0.17 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2526 2542 2.8 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2473 2488 0.032 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 2630 2648 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Gene3D G3DSA:2.60.40.10 2038 2136 1.7E-13 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Gene3D G3DSA:2.60.40.10 1942 2037 8.5E-12 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Gene3D G3DSA:2.60.40.10 1559 1654 7.2E-14 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Gene3D G3DSA:2.60.40.10 1842 1941 1.4E-12 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Gene3D G3DSA:2.60.40.10 1655 1752 1.2E-13 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Gene3D G3DSA:2.60.40.10 1459 1558 3.7E-13 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_07085 b2b9e56b3e7e6244e3ff57284517795c 2736 Pfam PF14252 Domain of unknown function (DUF4347) 25 174 2.9E-44 T 14-10-2018 IPR025592 Domain of unknown function DUF4347 TSH58p_29380 884e1eb766551bdaaf1a25dd0a4550e2 308 SUPERFAMILY SSF161098 101 288 3.14E-28 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_29380 884e1eb766551bdaaf1a25dd0a4550e2 308 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 27 77 7.9E-15 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TSH58p_29380 884e1eb766551bdaaf1a25dd0a4550e2 308 Gene3D G3DSA:1.10.3720.10 96 303 9.3E-23 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_29380 884e1eb766551bdaaf1a25dd0a4550e2 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 124 307 4.0E-29 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_16950 c0e6e490b14d439d7926eed07a41c919 497 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 293 304 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 TSH58p_16950 c0e6e490b14d439d7926eed07a41c919 497 Pfam PF00171 Aldehyde dehydrogenase family 30 489 6.3E-172 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TSH58p_16950 c0e6e490b14d439d7926eed07a41c919 497 Gene3D G3DSA:3.40.309.10 269 459 3.4E-185 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TSH58p_16950 c0e6e490b14d439d7926eed07a41c919 497 Gene3D G3DSA:3.40.605.10 36 484 3.4E-185 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TSH58p_16950 c0e6e490b14d439d7926eed07a41c919 497 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 265 272 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 TSH58p_16950 c0e6e490b14d439d7926eed07a41c919 497 SUPERFAMILY SSF53720 15 492 3.01E-172 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSH58p_16950 c0e6e490b14d439d7926eed07a41c919 497 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 41 488 3.5E-223 T 14-10-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 TSH58p_05835 c31e16488b32c64f6a5cac78126b09c2 533 Gene3D G3DSA:3.60.15.10 1 419 8.6E-149 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_05835 c31e16488b32c64f6a5cac78126b09c2 533 SMART SM00849 1 195 2.3E-15 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_05835 c31e16488b32c64f6a5cac78126b09c2 533 SUPERFAMILY SSF56281 2 402 1.57E-79 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_05835 c31e16488b32c64f6a5cac78126b09c2 533 Gene3D G3DSA:3.40.50.10710 187 337 8.6E-149 T 14-10-2018 TSH58p_05835 c31e16488b32c64f6a5cac78126b09c2 533 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 343 383 2.6E-8 T 14-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain TSH58p_05835 c31e16488b32c64f6a5cac78126b09c2 533 Gene3D G3DSA:3.10.20.580 430 532 2.9E-6 T 14-10-2018 TSH58p_05835 c31e16488b32c64f6a5cac78126b09c2 533 Pfam PF12706 Beta-lactamase superfamily domain 28 148 1.4E-12 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_11310 c556fec486ff4723351366450df9a747 232 Gene3D G3DSA:3.30.420.40 95 196 8.3E-43 T 14-10-2018 TSH58p_11310 c556fec486ff4723351366450df9a747 232 SUPERFAMILY SSF53067 112 210 1.68E-5 T 14-10-2018 TSH58p_11310 c556fec486ff4723351366450df9a747 232 Pfam PF00814 Glycoprotease family 32 123 5.0E-21 T 14-10-2018 IPR000905 Gcp-like domain TSH58p_11310 c556fec486ff4723351366450df9a747 232 SUPERFAMILY SSF53067 1 101 9.06E-27 T 14-10-2018 TSH58p_11310 c556fec486ff4723351366450df9a747 232 Gene3D G3DSA:3.30.420.40 3 221 8.3E-43 T 14-10-2018 TSH58p_11310 c556fec486ff4723351366450df9a747 232 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 221 3.7E-47 T 14-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 TSH58p_23725 4e208c510e407f4d7ca1f720786f542c 406 Gene3D G3DSA:3.50.50.60 31 403 6.4E-80 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_23725 4e208c510e407f4d7ca1f720786f542c 406 Pfam PF04820 Tryptophan halogenase 124 403 5.7E-12 T 14-10-2018 IPR006905 Flavin-dependent halogenase TSH58p_23725 4e208c510e407f4d7ca1f720786f542c 406 Pfam PF04820 Tryptophan halogenase 31 94 1.5E-5 T 14-10-2018 IPR006905 Flavin-dependent halogenase TSH58p_23725 4e208c510e407f4d7ca1f720786f542c 406 SUPERFAMILY SSF51905 31 396 2.59E-31 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_23725 4e208c510e407f4d7ca1f720786f542c 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 31 53 6.7E-9 T 14-10-2018 TSH58p_23725 4e208c510e407f4d7ca1f720786f542c 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 331 347 6.7E-9 T 14-10-2018 TSH58p_23725 4e208c510e407f4d7ca1f720786f542c 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 182 197 6.7E-9 T 14-10-2018 TSH58p_23725 4e208c510e407f4d7ca1f720786f542c 406 Gene3D G3DSA:3.30.9.100 72 307 6.4E-80 T 14-10-2018 TSH58p_27900 233b908090a7c79602aac2121db25943 387 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 95 113 - T 14-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 TSH58p_27900 233b908090a7c79602aac2121db25943 387 SUPERFAMILY SSF53901 10 260 1.08E-71 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_27900 233b908090a7c79602aac2121db25943 387 Pfam PF00108 Thiolase, N-terminal domain 13 256 9.7E-66 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 TSH58p_27900 233b908090a7c79602aac2121db25943 387 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 15 385 3.1E-130 T 14-10-2018 IPR002155 Thiolase GO:0016747 TSH58p_27900 233b908090a7c79602aac2121db25943 387 Pfam PF02803 Thiolase, C-terminal domain 265 385 1.0E-47 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 TSH58p_27900 233b908090a7c79602aac2121db25943 387 PIRSF PIRSF000429 8 387 1.8E-127 T 14-10-2018 IPR002155 Thiolase GO:0016747 TSH58p_27900 233b908090a7c79602aac2121db25943 387 Gene3D G3DSA:3.40.47.10 15 270 3.7E-139 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_27900 233b908090a7c79602aac2121db25943 387 SUPERFAMILY SSF53901 266 385 1.24E-43 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_27900 233b908090a7c79602aac2121db25943 387 ProSitePatterns PS00737 Thiolases signature 2. 333 349 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 TSH58p_27900 233b908090a7c79602aac2121db25943 387 Gene3D G3DSA:3.40.47.10 137 384 3.7E-139 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_03880 977b4aeef82da56fdacccca4095502a7 424 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 235 251 - T 14-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site TSH58p_03880 977b4aeef82da56fdacccca4095502a7 424 Gene3D G3DSA:3.20.20.10 76 292 4.6E-81 T 14-10-2018 IPR029066 PLP-binding barrel TSH58p_03880 977b4aeef82da56fdacccca4095502a7 424 Gene3D G3DSA:2.40.37.10 293 397 4.6E-81 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TSH58p_03880 977b4aeef82da56fdacccca4095502a7 424 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 298 382 1.9E-7 T 14-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 TSH58p_03880 977b4aeef82da56fdacccca4095502a7 424 SUPERFAMILY SSF51419 47 295 6.11E-49 T 14-10-2018 IPR029066 PLP-binding barrel TSH58p_03880 977b4aeef82da56fdacccca4095502a7 424 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 284 303 1.8E-22 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TSH58p_03880 977b4aeef82da56fdacccca4095502a7 424 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 99 111 1.8E-22 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TSH58p_03880 977b4aeef82da56fdacccca4095502a7 424 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 385 398 1.8E-22 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TSH58p_03880 977b4aeef82da56fdacccca4095502a7 424 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 78 96 1.8E-22 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TSH58p_03880 977b4aeef82da56fdacccca4095502a7 424 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 203 216 1.8E-22 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TSH58p_03880 977b4aeef82da56fdacccca4095502a7 424 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 69 294 4.7E-38 T 14-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 TSH58p_03880 977b4aeef82da56fdacccca4095502a7 424 SUPERFAMILY SSF50621 279 408 9.0E-28 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TSH58p_03880 977b4aeef82da56fdacccca4095502a7 424 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 78 96 - T 14-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site TSH58p_03880 977b4aeef82da56fdacccca4095502a7 424 PRINTS PR01182 Ornithine decarboxylase signature 315 328 1.3E-8 T 14-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 TSH58p_03880 977b4aeef82da56fdacccca4095502a7 424 PRINTS PR01182 Ornithine decarboxylase signature 76 103 1.3E-8 T 14-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 TSH58p_03880 977b4aeef82da56fdacccca4095502a7 424 PRINTS PR01182 Ornithine decarboxylase signature 372 385 1.3E-8 T 14-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 TSH58p_03880 977b4aeef82da56fdacccca4095502a7 424 PRINTS PR01182 Ornithine decarboxylase signature 351 361 1.3E-8 T 14-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 TSH58p_04540 4f3a2e9409488a1c7031e2130b2c059a 266 Gene3D G3DSA:3.60.15.10 2 266 2.4E-64 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_04540 4f3a2e9409488a1c7031e2130b2c059a 266 Pfam PF12706 Beta-lactamase superfamily domain 58 238 8.2E-34 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_04540 4f3a2e9409488a1c7031e2130b2c059a 266 SUPERFAMILY SSF56281 5 266 1.96E-42 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_09570 d6aa6c9a1dd26dee73f889cc747fe884 735 Gene3D G3DSA:3.30.450.20 144 279 1.4E-7 T 14-10-2018 TSH58p_09570 d6aa6c9a1dd26dee73f889cc747fe884 735 SUPERFAMILY SSF53098 535 710 3.98E-56 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily TSH58p_09570 d6aa6c9a1dd26dee73f889cc747fe884 735 SUPERFAMILY SSF55785 148 248 4.38E-7 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_09570 d6aa6c9a1dd26dee73f889cc747fe884 735 SMART SM00091 155 221 0.0014 T 14-10-2018 IPR000014 PAS domain TSH58p_09570 d6aa6c9a1dd26dee73f889cc747fe884 735 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 541 705 1.2E-34 T 14-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSH58p_09570 d6aa6c9a1dd26dee73f889cc747fe884 735 Gene3D G3DSA:3.30.420.10 538 712 1.6E-50 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TSH58p_09570 d6aa6c9a1dd26dee73f889cc747fe884 735 SMART SM00479 541 709 1.3E-54 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TSH58p_09570 d6aa6c9a1dd26dee73f889cc747fe884 735 Pfam PF00929 Exonuclease 543 700 3.7E-37 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TSH58p_09395 58302f596403056ccd8f64c042b0ef5e 228 Pfam PF00912 Transglycosylase 51 215 5.8E-49 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_09395 58302f596403056ccd8f64c042b0ef5e 228 SUPERFAMILY SSF53955 49 217 8.15E-57 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily TSH58p_09395 58302f596403056ccd8f64c042b0ef5e 228 Gene3D G3DSA:1.10.3810.10 47 220 1.2E-49 T 14-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_09395 58302f596403056ccd8f64c042b0ef5e 228 TIGRFAM TIGR02070 mono_pep_trsgly: monofunctional biosynthetic peptidoglycan transglycosylase 7 221 2.1E-81 T 14-10-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_09395 58302f596403056ccd8f64c042b0ef5e 228 Hamap MF_00766 Biosynthetic peptidoglycan transglycosylase [mtgA]. 7 221 41.683 T 14-10-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_16825 43671c0905c278e4784f14e94aa72f9e 432 PIRSF PIRSF006066 1 432 2.9E-152 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSH58p_16825 43671c0905c278e4784f14e94aa72f9e 432 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 7 419 4.3E-132 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TSH58p_16825 43671c0905c278e4784f14e94aa72f9e 432 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 426 5.4E-158 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSH58p_05025 af745b01c99b1abe909037455fceaac5 488 SUPERFAMILY SSF54292 4 88 9.18E-15 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TSH58p_05025 af745b01c99b1abe909037455fceaac5 488 Gene3D G3DSA:3.30.465.10 253 365 1.7E-35 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TSH58p_05025 af745b01c99b1abe909037455fceaac5 488 Gene3D G3DSA:1.10.150.120 88 198 2.9E-30 T 14-10-2018 TSH58p_05025 af745b01c99b1abe909037455fceaac5 488 Pfam PF01799 [2Fe-2S] binding domain 84 161 4.1E-28 T 14-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 TSH58p_05025 af745b01c99b1abe909037455fceaac5 488 Gene3D G3DSA:3.30.43.10 203 252 2.4E-21 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 TSH58p_05025 af745b01c99b1abe909037455fceaac5 488 SUPERFAMILY SSF47741 96 173 3.53E-29 T 14-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily TSH58p_05025 af745b01c99b1abe909037455fceaac5 488 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 11 56 2.1E-5 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 TSH58p_05025 af745b01c99b1abe909037455fceaac5 488 SUPERFAMILY SSF55447 371 477 5.36E-30 T 14-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily TSH58p_05025 af745b01c99b1abe909037455fceaac5 488 SUPERFAMILY SSF56176 186 366 8.63E-54 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TSH58p_05025 af745b01c99b1abe909037455fceaac5 488 PIRSF PIRSF036557 2 487 1.1E-194 T 14-10-2018 IPR012175 Xanthine dehydrogenase, small subunit, bacteria TSH58p_05025 af745b01c99b1abe909037455fceaac5 488 SMART SM01092 373 475 1.4E-30 T 14-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal TSH58p_05025 af745b01c99b1abe909037455fceaac5 488 Gene3D G3DSA:3.30.390.50 373 475 3.2E-27 T 14-10-2018 TSH58p_05025 af745b01c99b1abe909037455fceaac5 488 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 374 474 1.6E-28 T 14-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal TSH58p_05025 af745b01c99b1abe909037455fceaac5 488 TIGRFAM TIGR02963 xanthine_xdhA: xanthine dehydrogenase, small subunit 5 474 2.8E-188 T 14-10-2018 IPR014307 Xanthine dehydrogenase, small subunit GO:0004854|GO:0004855|GO:0050660|GO:0055114 KEGG: 00230+1.17.1.4|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999|Reactome: R-HSA-74259|Reactome: R-HSA-8851680 TSH58p_05025 af745b01c99b1abe909037455fceaac5 488 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 201 365 7.5E-53 T 14-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 TSH58p_05025 af745b01c99b1abe909037455fceaac5 488 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 41 49 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 TSH58p_05025 af745b01c99b1abe909037455fceaac5 488 Gene3D G3DSA:3.10.20.30 2 87 2.8E-23 T 14-10-2018 IPR012675 Beta-grasp domain superfamily TSH58p_12570 8aff60d96b69224ba432e5326f69b3e0 161 SUPERFAMILY SSF53098 12 156 2.34E-8 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily TSH58p_12570 8aff60d96b69224ba432e5326f69b3e0 161 Gene3D G3DSA:3.30.420.10 52 158 9.2E-6 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TSH58p_28385 30800b31c523601bd743749999feb9f2 259 SUPERFAMILY SSF51735 7 256 3.81E-61 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_28385 30800b31c523601bd743749999feb9f2 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.4E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_28385 30800b31c523601bd743749999feb9f2 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 1.4E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_28385 30800b31c523601bd743749999feb9f2 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.4E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_28385 30800b31c523601bd743749999feb9f2 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.4E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_28385 30800b31c523601bd743749999feb9f2 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.4E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_28385 30800b31c523601bd743749999feb9f2 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.4E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_28385 30800b31c523601bd743749999feb9f2 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 253 3.7E-39 T 14-10-2018 TSH58p_28385 30800b31c523601bd743749999feb9f2 259 Gene3D G3DSA:3.40.50.720 1 259 5.9E-63 T 14-10-2018 TSH58p_21955 f3e47d925c25d9d5ca21dda428d194bb 885 SUPERFAMILY SSF63737 7 199 7.45E-44 T 14-10-2018 TSH58p_21955 f3e47d925c25d9d5ca21dda428d194bb 885 Pfam PF11940 Domain of unknown function (DUF3458) Ig-like fold 451 555 5.5E-30 T 14-10-2018 IPR035414 Peptidase M1, alanyl aminopeptidase, Ig-like fold TSH58p_21955 f3e47d925c25d9d5ca21dda428d194bb 885 Gene3D G3DSA:2.60.40.1840 451 555 1.0E-34 T 14-10-2018 IPR038438 Alanyl aminopeptidase, Ig-like domain superfamily TSH58p_21955 f3e47d925c25d9d5ca21dda428d194bb 885 Pfam PF17432 Domain of unknown function (DUF3458_C) ARM repeats 560 882 4.6E-134 T 14-10-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal TSH58p_21955 f3e47d925c25d9d5ca21dda428d194bb 885 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 265 275 2.3E-8 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TSH58p_21955 f3e47d925c25d9d5ca21dda428d194bb 885 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 301 316 2.3E-8 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TSH58p_21955 f3e47d925c25d9d5ca21dda428d194bb 885 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 320 332 2.3E-8 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TSH58p_21955 f3e47d925c25d9d5ca21dda428d194bb 885 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 133 148 2.3E-8 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TSH58p_21955 f3e47d925c25d9d5ca21dda428d194bb 885 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 183 198 2.3E-8 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TSH58p_21955 f3e47d925c25d9d5ca21dda428d194bb 885 Pfam PF01433 Peptidase family M1 domain 215 446 5.7E-57 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TSH58p_21955 f3e47d925c25d9d5ca21dda428d194bb 885 SUPERFAMILY SSF55486 211 457 5.57E-77 T 14-10-2018 TSH58p_21955 f3e47d925c25d9d5ca21dda428d194bb 885 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 13 881 0.0 T 14-10-2018 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 TSH58p_21955 f3e47d925c25d9d5ca21dda428d194bb 885 Gene3D G3DSA:1.25.50.10 557 882 2.6E-135 T 14-10-2018 IPR037144 Peptidase M1, alanyl aminopeptidase, C-terminal domain superfamily TSH58p_21955 f3e47d925c25d9d5ca21dda428d194bb 885 Gene3D G3DSA:2.60.40.1730 16 201 5.1E-76 T 14-10-2018 TSH58p_21955 f3e47d925c25d9d5ca21dda428d194bb 885 Gene3D G3DSA:1.10.1740.60 203 286 5.2E-40 T 14-10-2018 TSH58p_21955 f3e47d925c25d9d5ca21dda428d194bb 885 Gene3D G3DSA:1.10.390.10 287 450 3.7E-66 T 14-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily TSH58p_11140 cb36d552bda4c9c8d5a811b1c6879bc8 180 SUPERFAMILY SSF55729 11 171 1.31E-27 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_11140 cb36d552bda4c9c8d5a811b1c6879bc8 180 Gene3D G3DSA:3.40.630.30 7 174 3.0E-31 T 14-10-2018 TSH58p_11140 cb36d552bda4c9c8d5a811b1c6879bc8 180 Pfam PF00583 Acetyltransferase (GNAT) family 50 145 3.2E-12 T 14-10-2018 IPR000182 GNAT domain TSH58p_11230 cb5db384d51d0c73d8bc81a103574162 325 SUPERFAMILY SSF53807 27 323 5.89E-81 T 14-10-2018 TSH58p_11230 cb5db384d51d0c73d8bc81a103574162 325 Gene3D G3DSA:3.40.50.1980 213 325 3.2E-41 T 14-10-2018 TSH58p_11230 cb5db384d51d0c73d8bc81a103574162 325 Pfam PF01297 Zinc-uptake complex component A periplasmic 30 322 1.7E-65 T 14-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 TSH58p_11230 cb5db384d51d0c73d8bc81a103574162 325 Gene3D G3DSA:3.40.50.1980 29 212 4.4E-56 T 14-10-2018 TSH58p_19045 3cf4191f013623b4a30c21b85681fbeb 847 Pfam PF00360 Phytochrome region 322 498 6.9E-51 T 14-10-2018 IPR013515 Phytochrome, central region GO:0006355|GO:0009584|GO:0018298 TSH58p_19045 3cf4191f013623b4a30c21b85681fbeb 847 Pfam PF00072 Response regulator receiver domain 735 833 1.9E-6 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_19045 3cf4191f013623b4a30c21b85681fbeb 847 Pfam PF01590 GAF domain 141 301 8.7E-18 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_19045 3cf4191f013623b4a30c21b85681fbeb 847 SUPERFAMILY SSF55781 128 308 2.84E-58 T 14-10-2018 TSH58p_19045 3cf4191f013623b4a30c21b85681fbeb 847 SMART SM00911 520 602 2.7E-28 T 14-10-2018 IPR011102 Signal transduction histidine kinase, HWE region GO:0004673 TSH58p_19045 3cf4191f013623b4a30c21b85681fbeb 847 SUPERFAMILY SSF52172 734 845 1.57E-15 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_19045 3cf4191f013623b4a30c21b85681fbeb 847 SMART SM00448 733 841 1.0E-5 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_19045 3cf4191f013623b4a30c21b85681fbeb 847 PRINTS PR01033 Phytochrome signature 156 175 2.9E-15 T 14-10-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 TSH58p_19045 3cf4191f013623b4a30c21b85681fbeb 847 PRINTS PR01033 Phytochrome signature 242 263 2.9E-15 T 14-10-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 TSH58p_19045 3cf4191f013623b4a30c21b85681fbeb 847 PRINTS PR01033 Phytochrome signature 459 477 2.9E-15 T 14-10-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 TSH58p_19045 3cf4191f013623b4a30c21b85681fbeb 847 PRINTS PR01033 Phytochrome signature 425 444 2.9E-15 T 14-10-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 TSH58p_19045 3cf4191f013623b4a30c21b85681fbeb 847 PIRSF PIRSF036397 3 847 8.9E-297 T 14-10-2018 IPR009219 Bacteriophytochrome, CheY-like TSH58p_19045 3cf4191f013623b4a30c21b85681fbeb 847 Gene3D G3DSA:3.30.450.40 7 472 3.1E-169 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_19045 3cf4191f013623b4a30c21b85681fbeb 847 Gene3D G3DSA:3.30.565.10 578 701 3.4E-7 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_19045 3cf4191f013623b4a30c21b85681fbeb 847 Gene3D G3DSA:3.40.50.2300 732 846 4.5E-35 T 14-10-2018 TSH58p_19045 3cf4191f013623b4a30c21b85681fbeb 847 SUPERFAMILY SSF55781 315 501 7.85E-55 T 14-10-2018 TSH58p_19045 3cf4191f013623b4a30c21b85681fbeb 847 Gene3D G3DSA:3.30.450.270 310 489 3.1E-169 T 14-10-2018 TSH58p_19045 3cf4191f013623b4a30c21b85681fbeb 847 SUPERFAMILY SSF55874 597 702 8.42E-5 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_19045 3cf4191f013623b4a30c21b85681fbeb 847 Pfam PF08446 PAS fold 10 116 6.5E-13 T 14-10-2018 IPR013654 PAS fold-2 GO:0006355 TSH58p_19045 3cf4191f013623b4a30c21b85681fbeb 847 Pfam PF07536 HWE histidine kinase 520 602 1.1E-20 T 14-10-2018 IPR011102 Signal transduction histidine kinase, HWE region GO:0004673 TSH58p_19045 3cf4191f013623b4a30c21b85681fbeb 847 SMART SM00065 141 314 1.1E-10 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_19045 3cf4191f013623b4a30c21b85681fbeb 847 Gene3D G3DSA:3.30.450.20 17 243 3.1E-169 T 14-10-2018 TSH58p_19045 3cf4191f013623b4a30c21b85681fbeb 847 SUPERFAMILY SSF55785 3 117 8.24E-32 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_00350 905f0f80419e5e2c113fccb910ffe5d6 457 Gene3D G3DSA:2.40.30.170 346 434 1.3E-8 T 14-10-2018 TSH58p_00350 905f0f80419e5e2c113fccb910ffe5d6 457 Pfam PF13437 HlyD family secretion protein 309 410 7.0E-12 T 14-10-2018 TSH58p_00350 905f0f80419e5e2c113fccb910ffe5d6 457 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 38 456 8.5E-112 T 14-10-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 TSH58p_00350 905f0f80419e5e2c113fccb910ffe5d6 457 Gene3D G3DSA:1.10.287.470 252 308 1.3E-8 T 14-10-2018 TSH58p_00350 905f0f80419e5e2c113fccb910ffe5d6 457 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 87 107 3.3E-45 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_00350 905f0f80419e5e2c113fccb910ffe5d6 457 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 321 342 3.3E-45 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_00350 905f0f80419e5e2c113fccb910ffe5d6 457 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 354 378 3.3E-45 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_00350 905f0f80419e5e2c113fccb910ffe5d6 457 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 421 436 3.3E-45 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_00350 905f0f80419e5e2c113fccb910ffe5d6 457 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 378 401 3.3E-45 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_00350 905f0f80419e5e2c113fccb910ffe5d6 457 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 436 456 3.3E-45 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_00350 905f0f80419e5e2c113fccb910ffe5d6 457 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 45 68 3.3E-45 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TSH58p_00350 905f0f80419e5e2c113fccb910ffe5d6 457 Gene3D G3DSA:1.10.287.470 110 184 1.3E-6 T 14-10-2018 TSH58p_00350 905f0f80419e5e2c113fccb910ffe5d6 457 Gene3D G3DSA:2.40.50.100 84 188 1.3E-6 T 14-10-2018 TSH58p_00350 905f0f80419e5e2c113fccb910ffe5d6 457 Gene3D G3DSA:2.40.50.100 309 345 1.3E-8 T 14-10-2018 TSH58p_00350 905f0f80419e5e2c113fccb910ffe5d6 457 Pfam PF13533 Biotin-lipoyl like 85 121 1.4E-7 T 14-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain TSH58p_31430 5412c43fd75b4e899b8df9329bd5f605 275 SUPERFAMILY SSF53850 36 261 4.98E-40 T 14-10-2018 TSH58p_31430 5412c43fd75b4e899b8df9329bd5f605 275 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 260 3.7E-40 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_31430 5412c43fd75b4e899b8df9329bd5f605 275 SMART SM00062 39 263 3.5E-32 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_31430 5412c43fd75b4e899b8df9329bd5f605 275 Gene3D G3DSA:3.40.190.10 124 222 2.0E-43 T 14-10-2018 TSH58p_31430 5412c43fd75b4e899b8df9329bd5f605 275 Gene3D G3DSA:3.40.190.10 43 259 2.0E-43 T 14-10-2018 TSH58p_09075 545e01565d40df4fb2a571df094e8a83 171 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 133 9.8E-7 T 14-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 TSH58p_09075 545e01565d40df4fb2a571df094e8a83 171 SUPERFAMILY SSF56300 1 141 2.59E-16 T 14-10-2018 TSH58p_09075 545e01565d40df4fb2a571df094e8a83 171 Gene3D G3DSA:3.60.21.10 1 170 3.4E-49 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like TSH58p_01635 3dc9fab1a5ae88f649b17bd7e9f81691 366 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 54 277 5.2E-18 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain TSH58p_01635 3dc9fab1a5ae88f649b17bd7e9f81691 366 Gene3D G3DSA:2.40.30.170 50 287 7.8E-63 T 14-10-2018 TSH58p_01635 3dc9fab1a5ae88f649b17bd7e9f81691 366 Gene3D G3DSA:2.40.420.20 43 359 7.8E-63 T 14-10-2018 TSH58p_01635 3dc9fab1a5ae88f649b17bd7e9f81691 366 Gene3D G3DSA:2.40.50.100 65 211 7.8E-63 T 14-10-2018 TSH58p_01635 3dc9fab1a5ae88f649b17bd7e9f81691 366 SUPERFAMILY SSF111369 54 285 1.96E-25 T 14-10-2018 TSH58p_01635 3dc9fab1a5ae88f649b17bd7e9f81691 366 Gene3D G3DSA:1.10.287.470 99 164 7.8E-63 T 14-10-2018 TSH58p_01635 3dc9fab1a5ae88f649b17bd7e9f81691 366 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 41 361 2.1E-70 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 TSH58p_27705 80229a3b0408b32851f4f324f791aa51 283 Gene3D G3DSA:3.40.50.1820 6 281 7.6E-92 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_27705 80229a3b0408b32851f4f324f791aa51 283 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 8 280 1.0E-125 T 14-10-2018 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801|Reactome: R-HSA-156590 TSH58p_27705 80229a3b0408b32851f4f324f791aa51 283 Pfam PF00756 Putative esterase 25 274 3.7E-59 T 14-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 TSH58p_27705 80229a3b0408b32851f4f324f791aa51 283 SUPERFAMILY SSF53474 5 280 8.04E-92 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_02755 3847c4f86344b1331747abc361fd84ae 554 Gene3D G3DSA:3.40.50.300 4 288 2.9E-88 T 14-10-2018 TSH58p_02755 3847c4f86344b1331747abc361fd84ae 554 ProSitePatterns PS00211 ABC transporters family signature. 426 440 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_02755 3847c4f86344b1331747abc361fd84ae 554 SUPERFAMILY SSF52540 278 525 8.16E-75 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_02755 3847c4f86344b1331747abc361fd84ae 554 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_02755 3847c4f86344b1331747abc361fd84ae 554 Pfam PF00005 ABC transporter 27 184 3.9E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_02755 3847c4f86344b1331747abc361fd84ae 554 Pfam PF00005 ABC transporter 304 453 6.9E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_02755 3847c4f86344b1331747abc361fd84ae 554 SMART SM00382 312 503 1.6E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_02755 3847c4f86344b1331747abc361fd84ae 554 SMART SM00382 35 234 3.0E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_02755 3847c4f86344b1331747abc361fd84ae 554 SUPERFAMILY SSF52540 6 256 1.78E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_02755 3847c4f86344b1331747abc361fd84ae 554 Gene3D G3DSA:3.40.50.300 292 528 5.3E-71 T 14-10-2018 TSH58p_02755 3847c4f86344b1331747abc361fd84ae 554 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 273 1.6E-7 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_02755 3847c4f86344b1331747abc361fd84ae 554 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 505 530 2.4E-5 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_06810 e75941a7deb9763fd1cb68f926cd8568 800 SMART SM00304 450 503 1.1E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_06810 e75941a7deb9763fd1cb68f926cd8568 800 Pfam PF16591 Helical bimodular sensor domain 26 251 9.3E-10 T 14-10-2018 IPR032255 Helical bimodular sensor domain TSH58p_06810 e75941a7deb9763fd1cb68f926cd8568 800 Pfam PF00672 HAMP domain 450 497 6.3E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_06810 e75941a7deb9763fd1cb68f926cd8568 800 Gene3D G3DSA:1.20.1440.210 43 282 1.2E-5 T 14-10-2018 TSH58p_06810 e75941a7deb9763fd1cb68f926cd8568 800 Gene3D G3DSA:1.20.1480.50 414 509 2.0E-14 T 14-10-2018 TSH58p_06810 e75941a7deb9763fd1cb68f926cd8568 800 SMART SM01358 26 293 3.0E-17 T 14-10-2018 IPR032255 Helical bimodular sensor domain TSH58p_06810 e75941a7deb9763fd1cb68f926cd8568 800 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 613 764 5.5E-30 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_06810 e75941a7deb9763fd1cb68f926cd8568 800 SMART SM00283 540 794 9.5E-47 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_06810 e75941a7deb9763fd1cb68f926cd8568 800 Gene3D G3DSA:1.10.287.950 510 800 6.1E-54 T 14-10-2018 TSH58p_06810 e75941a7deb9763fd1cb68f926cd8568 800 SUPERFAMILY SSF58104 470 793 1.06E-62 T 14-10-2018 TSH58p_06810 e75941a7deb9763fd1cb68f926cd8568 800 Gene3D G3DSA:1.20.1440.210 122 250 1.2E-5 T 14-10-2018 TSH58p_20265 240316d023227963bc74f2e692ecb2bb 259 Gene3D G3DSA:1.10.10.10 125 232 3.4E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_20265 240316d023227963bc74f2e692ecb2bb 259 SUPERFAMILY SSF46894 120 225 8.5E-22 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_20265 240316d023227963bc74f2e692ecb2bb 259 SMART SM00862 146 223 7.8E-23 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_20265 240316d023227963bc74f2e692ecb2bb 259 SUPERFAMILY SSF52172 1 134 1.39E-10 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_20265 240316d023227963bc74f2e692ecb2bb 259 Gene3D G3DSA:3.40.50.2300 1 124 2.0E-11 T 14-10-2018 TSH58p_20265 240316d023227963bc74f2e692ecb2bb 259 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 223 2.1E-20 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_11255 2cf74701ef9b2f784723c3e67d61f9ed 277 Pfam PF04519 Polymer-forming cytoskeletal 145 240 3.4E-19 T 14-10-2018 IPR007607 Bactofilin A/B TSH58p_29445 b373c13a29d8366157690b990be1e646 291 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 15 284 5.4E-101 T 14-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_29445 b373c13a29d8366157690b990be1e646 291 Gene3D G3DSA:1.20.140.160 150 286 7.0E-16 T 14-10-2018 TSH58p_29445 b373c13a29d8366157690b990be1e646 291 Gene3D G3DSA:1.20.120.1810 14 120 5.1E-32 T 14-10-2018 TSH58p_29445 b373c13a29d8366157690b990be1e646 291 PRINTS PR00046 Major sigma-70 factor signature 254 269 5.5E-22 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_29445 b373c13a29d8366157690b990be1e646 291 PRINTS PR00046 Major sigma-70 factor signature 269 280 5.5E-22 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_29445 b373c13a29d8366157690b990be1e646 291 PRINTS PR00046 Major sigma-70 factor signature 77 90 5.5E-22 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_29445 b373c13a29d8366157690b990be1e646 291 PRINTS PR00046 Major sigma-70 factor signature 101 109 5.5E-22 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_29445 b373c13a29d8366157690b990be1e646 291 PRINTS PR00046 Major sigma-70 factor signature 235 247 5.5E-22 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_29445 b373c13a29d8366157690b990be1e646 291 Pfam PF04542 Sigma-70 region 2 53 121 6.2E-16 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_29445 b373c13a29d8366157690b990be1e646 291 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 254 280 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_29445 b373c13a29d8366157690b990be1e646 291 PIRSF PIRSF000770 14 288 1.5E-33 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_29445 b373c13a29d8366157690b990be1e646 291 Pfam PF04545 Sigma-70, region 4 231 281 2.9E-15 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 TSH58p_29445 b373c13a29d8366157690b990be1e646 291 SUPERFAMILY SSF88946 12 121 3.61E-39 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_29445 b373c13a29d8366157690b990be1e646 291 SUPERFAMILY SSF88659 195 286 1.23E-18 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSH58p_29445 b373c13a29d8366157690b990be1e646 291 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 48 283 5.6E-31 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TSH58p_21845 a36bc185e578081abaa4b4560151bb06 494 SUPERFAMILY SSF56300 107 407 2.02E-10 T 14-10-2018 TSH58p_21845 a36bc185e578081abaa4b4560151bb06 494 Gene3D G3DSA:3.60.21.70 103 405 4.8E-6 T 14-10-2018 IPR038607 PhoD-like superfamily TSH58p_06505 386521c4ff77a6654530d45096b07991 234 Pfam PF01895 PhoU domain 128 210 1.3E-18 T 14-10-2018 IPR026022 PhoU domain TSH58p_06505 386521c4ff77a6654530d45096b07991 234 Pfam PF01895 PhoU domain 24 110 2.4E-21 T 14-10-2018 IPR026022 PhoU domain TSH58p_06505 386521c4ff77a6654530d45096b07991 234 PIRSF PIRSF003107 6 224 7.2E-57 T 14-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 TSH58p_06505 386521c4ff77a6654530d45096b07991 234 Gene3D G3DSA:1.20.58.220 120 228 1.9E-28 T 14-10-2018 IPR038078 PhoU-like domain superfamily TSH58p_06505 386521c4ff77a6654530d45096b07991 234 SUPERFAMILY SSF109755 11 222 4.4E-60 T 14-10-2018 TSH58p_06505 386521c4ff77a6654530d45096b07991 234 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 11 218 1.2E-57 T 14-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 TSH58p_06505 386521c4ff77a6654530d45096b07991 234 Gene3D G3DSA:1.20.58.220 2 119 4.7E-36 T 14-10-2018 IPR038078 PhoU-like domain superfamily TSH58p_23810 81028e620ceeab3b99ec9616493772cb 250 SUPERFAMILY SSF51735 1 211 9.85E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_23810 81028e620ceeab3b99ec9616493772cb 250 Gene3D G3DSA:3.40.50.720 2 249 2.2E-30 T 14-10-2018 TSH58p_23810 81028e620ceeab3b99ec9616493772cb 250 Pfam PF13460 NAD(P)H-binding 7 172 4.0E-8 T 14-10-2018 IPR016040 NAD(P)-binding domain TSH58p_01455 642096323935a1933e07f547d7974af0 836 Gene3D G3DSA:2.40.170.20 297 836 4.4E-169 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily TSH58p_01455 642096323935a1933e07f547d7974af0 836 SMART SM00965 88 139 6.5E-10 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 TSH58p_01455 642096323935a1933e07f547d7974af0 836 Pfam PF07715 TonB-dependent Receptor Plug Domain 186 285 8.0E-12 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain TSH58p_01455 642096323935a1933e07f547d7974af0 836 Pfam PF00593 TonB dependent receptor 408 834 9.9E-48 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel TSH58p_01455 642096323935a1933e07f547d7974af0 836 Pfam PF07660 Secretin and TonB N terminus short domain 88 138 2.8E-7 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 TSH58p_01455 642096323935a1933e07f547d7974af0 836 Gene3D G3DSA:2.170.130.10 164 296 7.8E-36 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily TSH58p_01455 642096323935a1933e07f547d7974af0 836 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 188 833 6.4E-108 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 TSH58p_01455 642096323935a1933e07f547d7974af0 836 SUPERFAMILY SSF56935 142 836 1.42E-116 T 14-10-2018 TSH58p_01455 642096323935a1933e07f547d7974af0 836 Gene3D G3DSA:3.55.50.30 58 161 8.6E-28 T 14-10-2018 TSH58p_04945 f4a95c3364cf98edf0c952ea69d74c2e 116 Pfam PF01022 Bacterial regulatory protein, arsR family 33 78 1.7E-11 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSH58p_04945 f4a95c3364cf98edf0c952ea69d74c2e 116 SUPERFAMILY SSF46785 14 106 5.79E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_04945 f4a95c3364cf98edf0c952ea69d74c2e 116 SMART SM00418 26 104 1.5E-24 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSH58p_04945 f4a95c3364cf98edf0c952ea69d74c2e 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 75 90 1.4E-10 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSH58p_04945 f4a95c3364cf98edf0c952ea69d74c2e 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 1.4E-10 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSH58p_04945 f4a95c3364cf98edf0c952ea69d74c2e 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 28 43 1.4E-10 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSH58p_04945 f4a95c3364cf98edf0c952ea69d74c2e 116 Gene3D G3DSA:1.10.10.10 5 115 3.4E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_25090 25dc625b0cfb400741bcdea3a565d5fd 1286 Pfam PF14559 Tetratricopeptide repeat 900 961 7.0E-9 T 14-10-2018 TSH58p_25090 25dc625b0cfb400741bcdea3a565d5fd 1286 SMART SM00028 851 884 3.5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25090 25dc625b0cfb400741bcdea3a565d5fd 1286 SMART SM00028 885 919 400.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25090 25dc625b0cfb400741bcdea3a565d5fd 1286 SMART SM00028 954 987 170.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25090 25dc625b0cfb400741bcdea3a565d5fd 1286 SMART SM00028 817 850 230.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25090 25dc625b0cfb400741bcdea3a565d5fd 1286 SMART SM00028 920 953 0.0053 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25090 25dc625b0cfb400741bcdea3a565d5fd 1286 Gene3D G3DSA:1.25.40.10 770 896 5.6E-15 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25090 25dc625b0cfb400741bcdea3a565d5fd 1286 Pfam PF04724 Glycosyltransferase family 17 480 687 7.3E-29 T 14-10-2018 IPR006813 Glycosyl transferase, family 17 GO:0003830|GO:0006487|GO:0016020 KEGG: 00510+2.4.1.144|MetaCyc: PWY-7426|Reactome: R-HSA-975574 TSH58p_25090 25dc625b0cfb400741bcdea3a565d5fd 1286 SUPERFAMILY SSF48452 774 977 4.93E-24 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25090 25dc625b0cfb400741bcdea3a565d5fd 1286 SUPERFAMILY SSF53756 1006 1254 8.16E-23 T 14-10-2018 TSH58p_25090 25dc625b0cfb400741bcdea3a565d5fd 1286 Gene3D G3DSA:3.40.50.2000 24 161 1.5E-20 T 14-10-2018 TSH58p_25090 25dc625b0cfb400741bcdea3a565d5fd 1286 Gene3D G3DSA:1.25.40.10 897 989 6.3E-16 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25090 25dc625b0cfb400741bcdea3a565d5fd 1286 SUPERFAMILY SSF53756 20 368 1.41E-28 T 14-10-2018 TSH58p_25090 25dc625b0cfb400741bcdea3a565d5fd 1286 Gene3D G3DSA:3.40.50.2000 1164 1254 2.2E-5 T 14-10-2018 TSH58p_25090 25dc625b0cfb400741bcdea3a565d5fd 1286 Pfam PF13692 Glycosyl transferases group 1 191 319 6.9E-11 T 14-10-2018 TSH58p_25090 25dc625b0cfb400741bcdea3a565d5fd 1286 Pfam PF13432 Tetratricopeptide repeat 823 885 1.2E-4 T 14-10-2018 TSH58p_25090 25dc625b0cfb400741bcdea3a565d5fd 1286 Gene3D G3DSA:3.40.50.2000 162 330 1.5E-20 T 14-10-2018 TSH58p_31270 b6f7ea0a9d1bd58c18b3a22435669787 328 Gene3D G3DSA:3.40.50.2020 154 303 5.3E-85 T 14-10-2018 TSH58p_31270 b6f7ea0a9d1bd58c18b3a22435669787 328 SMART SM01400 6 126 1.9E-40 T 14-10-2018 TSH58p_31270 b6f7ea0a9d1bd58c18b3a22435669787 328 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 19 126 1.2E-27 T 14-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TSH58p_31270 b6f7ea0a9d1bd58c18b3a22435669787 328 Pfam PF14572 Phosphoribosyl synthetase-associated domain 217 325 1.4E-18 T 14-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TSH58p_31270 b6f7ea0a9d1bd58c18b3a22435669787 328 Gene3D G3DSA:3.40.50.2020 19 315 5.3E-85 T 14-10-2018 TSH58p_31270 b6f7ea0a9d1bd58c18b3a22435669787 328 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 19 326 1.9E-74 T 14-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TSH58p_31270 b6f7ea0a9d1bd58c18b3a22435669787 328 SUPERFAMILY SSF53271 76 318 1.2E-35 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like TSH58p_00890 e3ea524e0a07d869e55b0bf22c6a4df0 733 Pfam PF13533 Biotin-lipoyl like 469 510 4.7E-9 T 14-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain TSH58p_00890 e3ea524e0a07d869e55b0bf22c6a4df0 733 SUPERFAMILY SSF111369 463 567 2.62E-5 T 14-10-2018 TSH58p_00890 e3ea524e0a07d869e55b0bf22c6a4df0 733 Gene3D G3DSA:2.40.30.170 596 637 1.2E-17 T 14-10-2018 TSH58p_00890 e3ea524e0a07d869e55b0bf22c6a4df0 733 Gene3D G3DSA:2.40.50.100 468 595 1.2E-17 T 14-10-2018 TSH58p_00890 e3ea524e0a07d869e55b0bf22c6a4df0 733 Gene3D G3DSA:1.10.287.470 499 558 1.2E-17 T 14-10-2018 TSH58p_00890 e3ea524e0a07d869e55b0bf22c6a4df0 733 Pfam PF13437 HlyD family secretion protein 559 637 7.1E-6 T 14-10-2018 TSH58p_04895 2364d49a33d25c647386c3a66cca1ea3 298 TIGRFAM TIGR03381 agmatine_aguB: N-carbamoylputrescine amidase 9 286 4.0E-144 T 14-10-2018 IPR017755 N-carbamoylputrescine amidase GO:0006596|GO:0050126 KEGG: 00330+3.5.1.53|MetaCyc: PWY-43 TSH58p_04895 2364d49a33d25c647386c3a66cca1ea3 298 Gene3D G3DSA:3.60.110.10 2 297 7.3E-114 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TSH58p_04895 2364d49a33d25c647386c3a66cca1ea3 298 Pfam PF00795 Carbon-nitrogen hydrolase 10 270 1.7E-56 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 TSH58p_04895 2364d49a33d25c647386c3a66cca1ea3 298 SUPERFAMILY SSF56317 7 287 1.1E-85 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TSH58p_04640 4253cb95624cdb82118331e668578a72 174 SUPERFAMILY SSF55729 1 163 8.92E-31 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_04640 4253cb95624cdb82118331e668578a72 174 Gene3D G3DSA:3.40.630.30 1 174 3.3E-50 T 14-10-2018 TSH58p_04640 4253cb95624cdb82118331e668578a72 174 Pfam PF13420 Acetyltransferase (GNAT) domain 3 157 1.3E-25 T 14-10-2018 TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 Gene3D G3DSA:3.30.450.20 208 329 1.5E-10 T 14-10-2018 TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 Pfam PF00512 His Kinase A (phospho-acceptor) domain 467 532 1.3E-17 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 PRINTS PR00344 Bacterial sensor protein C-terminal signature 684 697 1.1E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 PRINTS PR00344 Bacterial sensor protein C-terminal signature 660 678 1.1E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 PRINTS PR00344 Bacterial sensor protein C-terminal signature 625 639 1.1E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 Pfam PF12860 PAS fold 92 206 3.5E-18 T 14-10-2018 TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 Pfam PF12860 PAS fold 220 332 1.6E-30 T 14-10-2018 TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 SMART SM00387 579 700 3.6E-37 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 Gene3D G3DSA:3.40.50.2300 852 989 3.3E-38 T 14-10-2018 TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 SUPERFAMILY SSF47384 453 533 3.14E-20 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 Pfam PF01627 Hpt domain 1046 1118 8.1E-10 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 SUPERFAMILY SSF55785 198 326 2.27E-11 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 SUPERFAMILY SSF52172 851 982 5.55E-37 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 Pfam PF13426 PAS domain 351 446 5.4E-11 T 14-10-2018 IPR000014 PAS domain TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 SUPERFAMILY SSF55785 73 199 1.59E-5 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 SMART SM00388 467 532 3.1E-23 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 SUPERFAMILY SSF55785 325 445 8.38E-23 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 Gene3D G3DSA:1.10.287.130 444 530 2.2E-26 T 14-10-2018 TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 Gene3D G3DSA:3.30.450.20 69 207 3.9E-7 T 14-10-2018 TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 336 454 6.4E-20 T 14-10-2018 IPR000014 PAS domain TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 579 699 7.8E-30 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 SUPERFAMILY SSF47226 1023 1135 2.09E-18 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 SMART SM00091 340 404 1.3E-10 T 14-10-2018 IPR000014 PAS domain TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 SMART SM00091 85 151 70.0 T 14-10-2018 IPR000014 PAS domain TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 SMART SM00091 213 281 2.7 T 14-10-2018 IPR000014 PAS domain TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 Gene3D G3DSA:1.20.120.160 1019 1137 5.1E-21 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 SMART SM00448 853 972 1.0E-36 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 Gene3D G3DSA:3.30.450.20 330 443 1.8E-24 T 14-10-2018 TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 Pfam PF00072 Response regulator receiver domain 855 972 4.5E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 Gene3D G3DSA:3.30.565.10 531 700 1.2E-49 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_11755 b5b744f68c92f311ac6ca18b66b57274 1143 SUPERFAMILY SSF55874 521 698 2.62E-44 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_30150 6d1b4c9b6fa6ed5acb5862d9c0302ad7 392 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 5 370 5.4E-40 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 TSH58p_30150 6d1b4c9b6fa6ed5acb5862d9c0302ad7 392 SUPERFAMILY SSF53335 3 372 5.81E-65 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_30150 6d1b4c9b6fa6ed5acb5862d9c0302ad7 392 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 160 173 3.0E-7 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 TSH58p_30150 6d1b4c9b6fa6ed5acb5862d9c0302ad7 392 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 115 129 3.0E-7 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 TSH58p_30150 6d1b4c9b6fa6ed5acb5862d9c0302ad7 392 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 3 19 3.0E-7 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 TSH58p_30150 6d1b4c9b6fa6ed5acb5862d9c0302ad7 392 Gene3D G3DSA:3.40.50.150 2 210 6.4E-37 T 14-10-2018 TSH58p_30150 6d1b4c9b6fa6ed5acb5862d9c0302ad7 392 Gene3D G3DSA:3.90.120.10 315 362 5.1E-8 T 14-10-2018 TSH58p_30150 6d1b4c9b6fa6ed5acb5862d9c0302ad7 392 Pfam PF00145 C-5 cytosine-specific DNA methylase 4 371 2.3E-42 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 TSH58p_29990 6d1b4c9b6fa6ed5acb5862d9c0302ad7 392 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 5 370 5.4E-40 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 TSH58p_29990 6d1b4c9b6fa6ed5acb5862d9c0302ad7 392 SUPERFAMILY SSF53335 3 372 5.81E-65 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_29990 6d1b4c9b6fa6ed5acb5862d9c0302ad7 392 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 160 173 3.0E-7 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 TSH58p_29990 6d1b4c9b6fa6ed5acb5862d9c0302ad7 392 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 115 129 3.0E-7 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 TSH58p_29990 6d1b4c9b6fa6ed5acb5862d9c0302ad7 392 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 3 19 3.0E-7 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 TSH58p_29990 6d1b4c9b6fa6ed5acb5862d9c0302ad7 392 Gene3D G3DSA:3.40.50.150 2 210 6.4E-37 T 14-10-2018 TSH58p_29990 6d1b4c9b6fa6ed5acb5862d9c0302ad7 392 Gene3D G3DSA:3.90.120.10 315 362 5.1E-8 T 14-10-2018 TSH58p_29990 6d1b4c9b6fa6ed5acb5862d9c0302ad7 392 Pfam PF00145 C-5 cytosine-specific DNA methylase 4 371 2.3E-42 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 TSH58p_02230 b71b9fa6d586d6f21de4248ed1bf0b64 527 Gene3D G3DSA:3.10.105.10 284 499 1.8E-122 T 14-10-2018 TSH58p_02230 b71b9fa6d586d6f21de4248ed1bf0b64 527 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 91 442 4.0E-86 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain TSH58p_02230 b71b9fa6d586d6f21de4248ed1bf0b64 527 SUPERFAMILY SSF53850 48 516 3.62E-122 T 14-10-2018 TSH58p_02230 b71b9fa6d586d6f21de4248ed1bf0b64 527 PIRSF PIRSF002741 40 523 2.9E-103 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TSH58p_02230 b71b9fa6d586d6f21de4248ed1bf0b64 527 Gene3D G3DSA:3.40.190.10 209 509 1.8E-122 T 14-10-2018 TSH58p_02230 b71b9fa6d586d6f21de4248ed1bf0b64 527 Gene3D G3DSA:3.90.76.10 56 208 1.8E-122 T 14-10-2018 TSH58p_22515 8bdf51e4ed29bd6a3d5ddb6812b0e041 122 Pfam PF01521 Iron-sulphur cluster biosynthesis 17 118 8.0E-20 T 14-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 TSH58p_22515 8bdf51e4ed29bd6a3d5ddb6812b0e041 122 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 17 121 3.2E-38 T 14-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 TSH58p_22515 8bdf51e4ed29bd6a3d5ddb6812b0e041 122 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 103 120 - T 14-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 TSH58p_22515 8bdf51e4ed29bd6a3d5ddb6812b0e041 122 SUPERFAMILY SSF89360 16 111 1.0E-30 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 TSH58p_22515 8bdf51e4ed29bd6a3d5ddb6812b0e041 122 Gene3D G3DSA:2.60.300.12 16 122 3.8E-36 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 TSH58p_31990 717f229733e027089b7edd4fe85876ce 480 TIGRFAM TIGR03810 arg_ornith_anti: arginine-ornithine antiporter 9 478 1.1E-192 T 14-10-2018 IPR022461 Arginine/ornithine antiporter GO:0005887|GO:0006527|GO:0043858 TSH58p_31990 717f229733e027089b7edd4fe85876ce 480 Pfam PF13520 Amino acid permease 11 418 3.1E-68 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 TSH58p_31990 717f229733e027089b7edd4fe85876ce 480 TIGRFAM TIGR00905 2A0302: transporter, basic amino acid/polyamine antiporter (APA) family 4 478 3.7E-180 T 14-10-2018 IPR004754 Amino acid antiporter GO:0006865|GO:0016021 TSH58p_31990 717f229733e027089b7edd4fe85876ce 480 Gene3D G3DSA:1.20.1740.10 4 452 2.6E-59 T 14-10-2018 TSH58p_31990 717f229733e027089b7edd4fe85876ce 480 PIRSF PIRSF006060 1 479 2.7E-50 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 TSH58p_14280 6fda3be8e6592d065c44a39591e3e76c 314 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 11 288 44.688 T 14-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 TSH58p_14280 6fda3be8e6592d065c44a39591e3e76c 314 SUPERFAMILY SSF54211 144 286 3.64E-50 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSH58p_14280 6fda3be8e6592d065c44a39591e3e76c 314 Gene3D G3DSA:3.30.230.20 11 138 9.4E-50 T 14-10-2018 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 TSH58p_14280 6fda3be8e6592d065c44a39591e3e76c 314 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 11 294 1.5E-102 T 14-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 TSH58p_14280 6fda3be8e6592d065c44a39591e3e76c 314 Gene3D G3DSA:3.30.1700.10 139 300 2.2E-61 T 14-10-2018 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 TSH58p_14280 6fda3be8e6592d065c44a39591e3e76c 314 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 13 284 3.8E-110 T 14-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 TSH58p_14280 6fda3be8e6592d065c44a39591e3e76c 314 SUPERFAMILY SSF54211 11 136 2.43E-41 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSH58p_03970 152beba7aad8b7b30227aa6a3ca6a669 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.2E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03970 152beba7aad8b7b30227aa6a3ca6a669 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.2E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03970 152beba7aad8b7b30227aa6a3ca6a669 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.2E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03970 152beba7aad8b7b30227aa6a3ca6a669 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.2E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03970 152beba7aad8b7b30227aa6a3ca6a669 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.2E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03970 152beba7aad8b7b30227aa6a3ca6a669 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 2.2E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03970 152beba7aad8b7b30227aa6a3ca6a669 236 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_03970 152beba7aad8b7b30227aa6a3ca6a669 236 Pfam PF00106 short chain dehydrogenase 8 200 3.3E-52 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03970 152beba7aad8b7b30227aa6a3ca6a669 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.4E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03970 152beba7aad8b7b30227aa6a3ca6a669 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.4E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03970 152beba7aad8b7b30227aa6a3ca6a669 236 Gene3D G3DSA:3.40.50.720 1 236 5.4E-72 T 14-10-2018 TSH58p_03970 152beba7aad8b7b30227aa6a3ca6a669 236 SUPERFAMILY SSF51735 1 224 8.11E-66 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_13285 25bf8ceaf2b4bd4c3874219e8206aab1 582 SUPERFAMILY SSF55073 155 308 2.9E-23 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_13285 25bf8ceaf2b4bd4c3874219e8206aab1 582 SMART SM00052 316 566 3.3E-124 T 14-10-2018 IPR001633 EAL domain TSH58p_13285 25bf8ceaf2b4bd4c3874219e8206aab1 582 SMART SM00091 25 91 2.3E-6 T 14-10-2018 IPR000014 PAS domain TSH58p_13285 25bf8ceaf2b4bd4c3874219e8206aab1 582 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 147 302 3.9E-15 T 14-10-2018 IPR000160 GGDEF domain TSH58p_13285 25bf8ceaf2b4bd4c3874219e8206aab1 582 Gene3D G3DSA:3.20.20.450 320 574 1.4E-103 T 14-10-2018 IPR035919 EAL domain superfamily TSH58p_13285 25bf8ceaf2b4bd4c3874219e8206aab1 582 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 26 144 2.1E-10 T 14-10-2018 IPR000014 PAS domain TSH58p_13285 25bf8ceaf2b4bd4c3874219e8206aab1 582 SUPERFAMILY SSF141868 321 569 3.79E-90 T 14-10-2018 IPR035919 EAL domain superfamily TSH58p_13285 25bf8ceaf2b4bd4c3874219e8206aab1 582 Pfam PF00990 Diguanylate cyclase, GGDEF domain 149 301 1.7E-23 T 14-10-2018 IPR000160 GGDEF domain TSH58p_13285 25bf8ceaf2b4bd4c3874219e8206aab1 582 Pfam PF00563 EAL domain 323 561 3.7E-78 T 14-10-2018 IPR001633 EAL domain TSH58p_13285 25bf8ceaf2b4bd4c3874219e8206aab1 582 SUPERFAMILY SSF55785 30 140 3.14E-17 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_13285 25bf8ceaf2b4bd4c3874219e8206aab1 582 Pfam PF08448 PAS fold 31 140 3.0E-17 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_13285 25bf8ceaf2b4bd4c3874219e8206aab1 582 Gene3D G3DSA:3.30.70.270 147 319 7.3E-29 T 14-10-2018 TSH58p_13285 25bf8ceaf2b4bd4c3874219e8206aab1 582 SMART SM00267 138 306 7.6E-20 T 14-10-2018 IPR000160 GGDEF domain TSH58p_13285 25bf8ceaf2b4bd4c3874219e8206aab1 582 Gene3D G3DSA:3.30.450.20 17 146 3.8E-21 T 14-10-2018 TSH58p_19460 1c7147902d2e86d1d47599dbf2fc1dd9 529 Pfam PF01019 Gamma-glutamyltranspeptidase 25 524 9.4E-127 T 14-10-2018 TSH58p_19460 1c7147902d2e86d1d47599dbf2fc1dd9 529 Gene3D G3DSA:3.60.20.40 344 529 2.2E-67 T 14-10-2018 TSH58p_19460 1c7147902d2e86d1d47599dbf2fc1dd9 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 367 385 2.4E-22 T 14-10-2018 TSH58p_19460 1c7147902d2e86d1d47599dbf2fc1dd9 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 343 361 2.4E-22 T 14-10-2018 TSH58p_19460 1c7147902d2e86d1d47599dbf2fc1dd9 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 125 144 2.4E-22 T 14-10-2018 TSH58p_19460 1c7147902d2e86d1d47599dbf2fc1dd9 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 398 413 2.4E-22 T 14-10-2018 TSH58p_19460 1c7147902d2e86d1d47599dbf2fc1dd9 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 252 271 2.4E-22 T 14-10-2018 TSH58p_19460 1c7147902d2e86d1d47599dbf2fc1dd9 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 32 57 2.4E-22 T 14-10-2018 TSH58p_19460 1c7147902d2e86d1d47599dbf2fc1dd9 529 SUPERFAMILY SSF56235 5 529 4.44E-152 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_19460 1c7147902d2e86d1d47599dbf2fc1dd9 529 Gene3D G3DSA:1.10.246.130 240 343 4.1E-11 T 14-10-2018 TSH58p_06425 0f562b180f33f748ef96837f1dd287a0 440 PIRSF PIRSF000478 1 439 3.5E-145 T 14-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSH58p_06425 0f562b180f33f748ef96837f1dd287a0 440 SUPERFAMILY SSF54680 336 438 3.92E-26 T 14-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSH58p_06425 0f562b180f33f748ef96837f1dd287a0 440 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 4 423 4.3E-149 T 14-10-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSH58p_06425 0f562b180f33f748ef96837f1dd287a0 440 Pfam PF02885 Glycosyl transferase family, helical bundle domain 5 66 2.9E-22 T 14-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSH58p_06425 0f562b180f33f748ef96837f1dd287a0 440 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 112 127 - T 14-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSH58p_06425 0f562b180f33f748ef96837f1dd287a0 440 Gene3D G3DSA:3.40.1030.10 69 338 9.9E-101 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSH58p_06425 0f562b180f33f748ef96837f1dd287a0 440 Pfam PF00591 Glycosyl transferase family, a/b domain 79 308 1.3E-34 T 14-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSH58p_06425 0f562b180f33f748ef96837f1dd287a0 440 SUPERFAMILY SSF52418 71 332 2.88E-86 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSH58p_06425 0f562b180f33f748ef96837f1dd287a0 440 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 349 423 8.7E-18 T 14-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSH58p_06425 0f562b180f33f748ef96837f1dd287a0 440 Hamap MF_01628 Thymidine phosphorylase [deoA]. 1 438 45.623 T 14-10-2018 IPR013465 Thymidine phosphorylase GO:0006213|GO:0009032 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181 TSH58p_06425 0f562b180f33f748ef96837f1dd287a0 440 SUPERFAMILY SSF47648 2 69 2.22E-22 T 14-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSH58p_06425 0f562b180f33f748ef96837f1dd287a0 440 TIGRFAM TIGR02643 T_phosphoryl: thymidine phosphorylase 1 438 1.4E-194 T 14-10-2018 IPR013465 Thymidine phosphorylase GO:0006213|GO:0009032 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181 TSH58p_06425 0f562b180f33f748ef96837f1dd287a0 440 Gene3D G3DSA:1.20.970.10 3 67 1.4E-24 T 14-10-2018 TSH58p_06425 0f562b180f33f748ef96837f1dd287a0 440 Gene3D G3DSA:3.90.1170.30 339 433 1.3E-27 T 14-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSH58p_06425 0f562b180f33f748ef96837f1dd287a0 440 SMART SM00941 349 424 1.1E-20 T 14-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSH58p_01665 8a05398ca2fec0af246193097a2f9680 261 SUPERFAMILY SSF52833 157 251 7.6E-20 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_01665 8a05398ca2fec0af246193097a2f9680 261 Gene3D G3DSA:3.40.50.1400 9 132 1.6E-6 T 14-10-2018 TSH58p_01665 8a05398ca2fec0af246193097a2f9680 261 Gene3D G3DSA:3.40.30.10 155 256 1.0E-22 T 14-10-2018 TSH58p_01665 8a05398ca2fec0af246193097a2f9680 261 SUPERFAMILY SSF53800 24 166 4.74E-5 T 14-10-2018 TSH58p_01665 8a05398ca2fec0af246193097a2f9680 261 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 158 235 1.7E-7 T 14-10-2018 TSH58p_16305 cdb36467fa557aabfb058d42418ad09f 160 Gene3D G3DSA:3.30.420.270 70 139 6.6E-22 T 14-10-2018 TSH58p_16305 cdb36467fa557aabfb058d42418ad09f 160 TIGRFAM TIGR02801 tolR: protein TolR 22 142 9.8E-38 T 14-10-2018 IPR014168 Tol-Pal system protein TolR GO:0015031|GO:0016021 TSH58p_16305 cdb36467fa557aabfb058d42418ad09f 160 Pfam PF02472 Biopolymer transport protein ExbD/TolR 21 141 4.3E-28 T 14-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 TSH58p_30780 c86cc1795163ecd137d05dcf605b5df0 325 Gene3D G3DSA:1.10.3720.10 88 317 5.7E-23 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_30780 c86cc1795163ecd137d05dcf605b5df0 325 SUPERFAMILY SSF161098 94 310 1.24E-18 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_30780 c86cc1795163ecd137d05dcf605b5df0 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 322 1.5E-40 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_16650 71f467f2376db1f827d22ea7ddc629ef 398 Gene3D G3DSA:1.10.540.10 1 128 1.4E-39 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TSH58p_16650 71f467f2376db1f827d22ea7ddc629ef 398 SUPERFAMILY SSF47203 238 390 1.93E-45 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TSH58p_16650 71f467f2376db1f827d22ea7ddc629ef 398 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 226 3.5E-20 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TSH58p_16650 71f467f2376db1f827d22ea7ddc629ef 398 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 239 386 2.6E-36 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TSH58p_16650 71f467f2376db1f827d22ea7ddc629ef 398 SUPERFAMILY SSF56645 1 250 9.56E-61 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TSH58p_16650 71f467f2376db1f827d22ea7ddc629ef 398 Gene3D G3DSA:2.40.110.10 129 244 1.4E-33 T 14-10-2018 TSH58p_16650 71f467f2376db1f827d22ea7ddc629ef 398 Gene3D G3DSA:1.20.140.10 245 390 1.9E-38 T 14-10-2018 TSH58p_16650 71f467f2376db1f827d22ea7ddc629ef 398 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 125 4.5E-19 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TSH58p_08715 d5e0f0030aec66ab804b65d7dcfc9b42 80 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 2 78 1.2E-35 T 14-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSH58p_08715 d5e0f0030aec66ab804b65d7dcfc9b42 80 SUPERFAMILY SSF82697 1 78 3.31E-30 T 14-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSH58p_08715 d5e0f0030aec66ab804b65d7dcfc9b42 80 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 1 78 5.1E-33 T 14-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSH58p_08715 d5e0f0030aec66ab804b65d7dcfc9b42 80 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 9 78 1.0E-20 T 14-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSH58p_08715 d5e0f0030aec66ab804b65d7dcfc9b42 80 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 1 78 23.347 T 14-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSH58p_08715 d5e0f0030aec66ab804b65d7dcfc9b42 80 Gene3D G3DSA:3.30.1280.10 1 80 1.1E-34 T 14-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSH58p_28085 c33d7c116716cc690fe3cdad27b70ee3 359 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 180 191 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_28085 c33d7c116716cc690fe3cdad27b70ee3 359 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 16 49 0.0012 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal TSH58p_28085 c33d7c116716cc690fe3cdad27b70ee3 359 Pfam PF12800 4Fe-4S binding domain 70 82 0.0074 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_28085 c33d7c116716cc690fe3cdad27b70ee3 359 SUPERFAMILY SSF54862 62 356 1.57E-60 T 14-10-2018 TSH58p_28085 c33d7c116716cc690fe3cdad27b70ee3 359 Pfam PF13247 4Fe-4S dicluster domain 141 237 1.4E-21 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_28085 c33d7c116716cc690fe3cdad27b70ee3 359 Gene3D G3DSA:3.30.70.20 146 211 9.4E-50 T 14-10-2018 TSH58p_28085 c33d7c116716cc690fe3cdad27b70ee3 359 Gene3D G3DSA:3.30.70.20 60 252 9.4E-50 T 14-10-2018 TSH58p_13520 c6e2734cef082ee44bf30cad554d9e26 262 Hamap MF_00057 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase [kdsB]. 16 257 34.675 T 14-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 TSH58p_13520 c6e2734cef082ee44bf30cad554d9e26 262 Gene3D G3DSA:3.90.550.10 17 261 9.7E-77 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_13520 c6e2734cef082ee44bf30cad554d9e26 262 Pfam PF02348 Cytidylyltransferase 19 231 5.9E-39 T 14-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 TSH58p_13520 c6e2734cef082ee44bf30cad554d9e26 262 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 19 250 2.4E-61 T 14-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 TSH58p_13520 c6e2734cef082ee44bf30cad554d9e26 262 SUPERFAMILY SSF53448 19 259 2.82E-54 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_30705 8001a45ad72f15f0efcfb26d72741211 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 21 79 1.4E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_30705 8001a45ad72f15f0efcfb26d72741211 317 Gene3D G3DSA:3.40.190.290 109 310 1.0E-23 T 14-10-2018 TSH58p_30705 8001a45ad72f15f0efcfb26d72741211 317 Gene3D G3DSA:1.10.10.10 19 108 5.8E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_30705 8001a45ad72f15f0efcfb26d72741211 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 57 68 4.2E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_30705 8001a45ad72f15f0efcfb26d72741211 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 47 4.2E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_30705 8001a45ad72f15f0efcfb26d72741211 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 57 4.2E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_30705 8001a45ad72f15f0efcfb26d72741211 317 SUPERFAMILY SSF53850 107 312 4.22E-31 T 14-10-2018 TSH58p_30705 8001a45ad72f15f0efcfb26d72741211 317 SUPERFAMILY SSF46785 14 124 2.01E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_30705 8001a45ad72f15f0efcfb26d72741211 317 Pfam PF03466 LysR substrate binding domain 106 308 3.5E-30 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_16545 1ac6cac1c1ecc8282718b74bb23fedaf 227 PIRSF PIRSF000887 5 222 3.2E-50 T 14-10-2018 IPR024173 Phosphoesterase, MJ0037 TSH58p_16545 1ac6cac1c1ecc8282718b74bb23fedaf 227 SUPERFAMILY SSF56300 26 129 1.73E-12 T 14-10-2018 TSH58p_16545 1ac6cac1c1ecc8282718b74bb23fedaf 227 Pfam PF00149 Calcineurin-like phosphoesterase 26 122 4.4E-5 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TSH58p_16545 1ac6cac1c1ecc8282718b74bb23fedaf 227 TIGRFAM TIGR04123 P_estr_lig_assc: metallophosphoesterase, DNA ligase-associated 6 214 1.8E-68 T 14-10-2018 IPR026336 Metallophosphoesterase, DNA ligase-associated TSH58p_16545 1ac6cac1c1ecc8282718b74bb23fedaf 227 Gene3D G3DSA:3.60.21.10 25 165 2.4E-9 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like TSH58p_17910 50ee2483bf88452c575777a5bb4b8fec 179 TIGRFAM TIGR00213 GmhB_yaeD: D,D-heptose 1,7-bisphosphate phosphatase 4 174 3.3E-48 T 14-10-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 TSH58p_17910 50ee2483bf88452c575777a5bb4b8fec 179 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 4 147 5.5E-27 T 14-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 TSH58p_17910 50ee2483bf88452c575777a5bb4b8fec 179 Gene3D G3DSA:3.40.50.1000 1 178 1.5E-47 T 14-10-2018 IPR023214 HAD superfamily TSH58p_17910 50ee2483bf88452c575777a5bb4b8fec 179 Pfam PF13242 HAD-hyrolase-like 107 161 2.1E-10 T 14-10-2018 TSH58p_17910 50ee2483bf88452c575777a5bb4b8fec 179 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 4 150 1.4E-31 T 14-10-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 TSH58p_17910 50ee2483bf88452c575777a5bb4b8fec 179 PIRSF PIRSF004682 1 175 6.5E-50 T 14-10-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 TSH58p_17910 50ee2483bf88452c575777a5bb4b8fec 179 SUPERFAMILY SSF56784 1 178 5.99E-43 T 14-10-2018 IPR036412 HAD-like superfamily TSH58p_04590 a4b9f95f135b2cda59628a4e108a2d3c 447 SUPERFAMILY SSF55931 111 443 2.16E-106 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TSH58p_04590 a4b9f95f135b2cda59628a4e108a2d3c 447 Gene3D G3DSA:3.10.20.70 3 111 1.9E-8 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TSH58p_04590 a4b9f95f135b2cda59628a4e108a2d3c 447 SUPERFAMILY SSF54368 5 109 3.79E-21 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TSH58p_04590 a4b9f95f135b2cda59628a4e108a2d3c 447 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 246 261 - T 14-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TSH58p_04590 a4b9f95f135b2cda59628a4e108a2d3c 447 Pfam PF00120 Glutamine synthetase, catalytic domain 112 442 4.5E-104 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TSH58p_04590 a4b9f95f135b2cda59628a4e108a2d3c 447 SMART SM01230 110 366 1.9E-110 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TSH58p_04590 a4b9f95f135b2cda59628a4e108a2d3c 447 Gene3D G3DSA:3.30.590.10 113 445 1.3E-102 T 14-10-2018 TSH58p_15380 9d51215aa22bc14b54603d464f316716 365 Pfam PF02119 Flagellar P-ring protein 22 364 6.1E-141 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 TSH58p_15380 9d51215aa22bc14b54603d464f316716 365 Hamap MF_00416 Flagellar P-ring protein [flgI]. 1 365 37.09 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 TSH58p_15380 9d51215aa22bc14b54603d464f316716 365 PRINTS PR01010 Flagellar P-ring protein signature 104 121 2.3E-83 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 TSH58p_15380 9d51215aa22bc14b54603d464f316716 365 PRINTS PR01010 Flagellar P-ring protein signature 82 101 2.3E-83 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 TSH58p_15380 9d51215aa22bc14b54603d464f316716 365 PRINTS PR01010 Flagellar P-ring protein signature 37 52 2.3E-83 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 TSH58p_15380 9d51215aa22bc14b54603d464f316716 365 PRINTS PR01010 Flagellar P-ring protein signature 187 205 2.3E-83 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 TSH58p_15380 9d51215aa22bc14b54603d464f316716 365 PRINTS PR01010 Flagellar P-ring protein signature 57 72 2.3E-83 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 TSH58p_15380 9d51215aa22bc14b54603d464f316716 365 PRINTS PR01010 Flagellar P-ring protein signature 121 139 2.3E-83 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 TSH58p_15380 9d51215aa22bc14b54603d464f316716 365 PRINTS PR01010 Flagellar P-ring protein signature 251 263 2.3E-83 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 TSH58p_15380 9d51215aa22bc14b54603d464f316716 365 PRINTS PR01010 Flagellar P-ring protein signature 161 179 2.3E-83 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 TSH58p_15380 9d51215aa22bc14b54603d464f316716 365 PRINTS PR01010 Flagellar P-ring protein signature 22 37 2.3E-83 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 TSH58p_12400 4f500428a47e70b76e98b8ec7c82a000 447 Pfam PF00691 OmpA family 341 438 9.5E-9 T 14-10-2018 IPR006665 OmpA-like domain TSH58p_12400 4f500428a47e70b76e98b8ec7c82a000 447 Gene3D G3DSA:3.30.1330.60 304 447 7.2E-30 T 14-10-2018 IPR036737 OmpA-like domain superfamily TSH58p_12400 4f500428a47e70b76e98b8ec7c82a000 447 Gene3D G3DSA:1.25.40.590 61 219 9.0E-41 T 14-10-2018 IPR038522 Type IV / VI secretion system, DotU superfamily TSH58p_12400 4f500428a47e70b76e98b8ec7c82a000 447 SUPERFAMILY SSF103088 331 446 8.11E-20 T 14-10-2018 IPR036737 OmpA-like domain superfamily TSH58p_12400 4f500428a47e70b76e98b8ec7c82a000 447 TIGRFAM TIGR03349 IV_VI_DotU: type IV/VI secretion system protein, DotU family 63 272 3.2E-54 T 14-10-2018 IPR017732 Type IV / VI secretion system, DotU TSH58p_12400 4f500428a47e70b76e98b8ec7c82a000 447 Pfam PF09850 Type VI secretion system protein DotU 64 264 3.4E-55 T 14-10-2018 IPR017732 Type IV / VI secretion system, DotU TSH58p_04830 1d1ccb801faa8c75db4937f2ad8bed92 301 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 285 4.2E-54 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_25460 08409cce182720428d7e0dd1c348421e 94 SMART SM00857 11 94 4.7E-5 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 TSH58p_25460 08409cce182720428d7e0dd1c348421e 94 Gene3D G3DSA:3.40.50.1390 8 83 1.3E-22 T 14-10-2018 TSH58p_25460 08409cce182720428d7e0dd1c348421e 94 Pfam PF00239 Resolvase, N terminal domain 11 81 5.1E-18 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 TSH58p_25460 08409cce182720428d7e0dd1c348421e 94 SUPERFAMILY SSF53041 10 80 4.45E-17 T 14-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 TSH58p_02870 5780ae96e640352e78872499bd0e4d94 178 SUPERFAMILY SSF52172 38 162 1.35E-6 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_28755 19b9cf3ef847f83598d1f169c7c44f9e 142 Pfam PF06172 Cupin superfamily (DUF985) 8 134 3.1E-47 T 14-10-2018 IPR009327 Cupin domain of unknown function DUF985 TSH58p_28755 19b9cf3ef847f83598d1f169c7c44f9e 142 SUPERFAMILY SSF51182 4 140 4.07E-54 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_28755 19b9cf3ef847f83598d1f169c7c44f9e 142 Gene3D G3DSA:2.60.120.10 2 142 6.7E-57 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_05960 38964acd9149f531834b523b5bd0884f 514 Gene3D G3DSA:1.20.140.90 54 198 2.6E-39 T 14-10-2018 IPR038351 Malonyl-CoA decarboxylase, N-terminal domain superfamily KEGG: 00410+4.1.1.9|KEGG: 00640+4.1.1.9|Reactome: R-HSA-390247|Reactome: R-HSA-9033241 TSH58p_05960 38964acd9149f531834b523b5bd0884f 514 Gene3D G3DSA:3.40.630.150 201 513 6.6E-113 T 14-10-2018 TSH58p_05960 38964acd9149f531834b523b5bd0884f 514 Pfam PF05292 Malonyl-CoA decarboxylase C-terminal domain 202 483 1.6E-115 T 14-10-2018 IPR007956 Malonyl-CoA decarboxylase, C-terminal GO:0006633|GO:0050080 KEGG: 00410+4.1.1.9|KEGG: 00640+4.1.1.9|Reactome: R-HSA-390247|Reactome: R-HSA-9033241 TSH58p_05960 38964acd9149f531834b523b5bd0884f 514 Pfam PF17408 Malonyl-CoA decarboxylase N-terminal domain 112 199 2.5E-26 T 14-10-2018 IPR035372 Malonyl-CoA decarboxylase, N-terminal KEGG: 00410+4.1.1.9|KEGG: 00640+4.1.1.9|Reactome: R-HSA-390247|Reactome: R-HSA-9033241 TSH58p_29055 12f9bf7901dce4f605255f55af2e5fe1 563 Gene3D G3DSA:1.20.58.340 451 527 3.4E-6 T 14-10-2018 TSH58p_29055 12f9bf7901dce4f605255f55af2e5fe1 563 Pfam PF01544 CorA-like Mg2+ transporter protein 444 521 6.8E-9 T 14-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 TSH58p_29055 12f9bf7901dce4f605255f55af2e5fe1 563 SUPERFAMILY SSF144083 463 522 3.66E-7 T 14-10-2018 TSH58p_26905 162a6b7d740a361bda55db5eeeac57f0 483 Gene3D G3DSA:3.30.43.10 3 101 1.8E-26 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 TSH58p_26905 162a6b7d740a361bda55db5eeeac57f0 483 Pfam PF02913 FAD linked oxidases, C-terminal domain 225 478 5.1E-52 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 TSH58p_26905 162a6b7d740a361bda55db5eeeac57f0 483 Gene3D G3DSA:3.30.70.2190 225 348 1.9E-35 T 14-10-2018 TSH58p_26905 162a6b7d740a361bda55db5eeeac57f0 483 SUPERFAMILY SSF55103 198 481 2.78E-55 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 TSH58p_26905 162a6b7d740a361bda55db5eeeac57f0 483 SUPERFAMILY SSF56176 10 225 3.27E-75 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TSH58p_26905 162a6b7d740a361bda55db5eeeac57f0 483 Gene3D G3DSA:3.30.70.2740 349 439 2.7E-21 T 14-10-2018 TSH58p_26905 162a6b7d740a361bda55db5eeeac57f0 483 Gene3D G3DSA:3.30.465.10 104 223 1.3E-46 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TSH58p_26905 162a6b7d740a361bda55db5eeeac57f0 483 Gene3D G3DSA:1.10.45.10 440 480 5.3E-14 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 TSH58p_26905 162a6b7d740a361bda55db5eeeac57f0 483 Pfam PF01565 FAD binding domain 47 185 3.4E-36 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TSH58p_00045 b38a56e8d04232854a01d1176b5de89c 135 Gene3D G3DSA:3.40.50.12740 14 133 1.4E-45 T 14-10-2018 TSH58p_00045 b38a56e8d04232854a01d1176b5de89c 135 Pfam PF00072 Response regulator receiver domain 17 128 4.3E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_00045 b38a56e8d04232854a01d1176b5de89c 135 SMART SM00448 15 128 2.6E-40 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_00045 b38a56e8d04232854a01d1176b5de89c 135 SUPERFAMILY SSF52172 13 131 2.85E-40 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_03405 b38a56e8d04232854a01d1176b5de89c 135 Gene3D G3DSA:3.40.50.12740 14 133 1.4E-45 T 14-10-2018 TSH58p_03405 b38a56e8d04232854a01d1176b5de89c 135 Pfam PF00072 Response regulator receiver domain 17 128 4.3E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_03405 b38a56e8d04232854a01d1176b5de89c 135 SMART SM00448 15 128 2.6E-40 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_03405 b38a56e8d04232854a01d1176b5de89c 135 SUPERFAMILY SSF52172 13 131 2.85E-40 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_21800 5d26348f6ac9694b1a70e05b7d693174 127 SUPERFAMILY SSF52172 1 123 2.42E-28 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_21800 5d26348f6ac9694b1a70e05b7d693174 127 Gene3D G3DSA:3.40.50.2300 1 124 2.7E-28 T 14-10-2018 TSH58p_21800 5d26348f6ac9694b1a70e05b7d693174 127 SMART SM00448 1 115 1.8E-18 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_21800 5d26348f6ac9694b1a70e05b7d693174 127 Pfam PF00072 Response regulator receiver domain 3 110 9.7E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_05755 ffda6b5f7c7031fcea4088a587713b04 185 SUPERFAMILY SSF55194 6 184 3.92E-67 T 14-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 TSH58p_05755 ffda6b5f7c7031fcea4088a587713b04 185 Gene3D G3DSA:3.30.1360.40 31 105 4.0E-68 T 14-10-2018 TSH58p_05755 ffda6b5f7c7031fcea4088a587713b04 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 4.6E-63 T 14-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 TSH58p_05755 ffda6b5f7c7031fcea4088a587713b04 185 Pfam PF01765 Ribosome recycling factor 20 183 1.1E-60 T 14-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 TSH58p_05755 ffda6b5f7c7031fcea4088a587713b04 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 24.945 T 14-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 TSH58p_05755 ffda6b5f7c7031fcea4088a587713b04 185 Gene3D G3DSA:1.10.132.20 12 182 4.0E-68 T 14-10-2018 TSH58p_25975 0443214ce82f647712977ee36c3f6166 242 Pfam PF03591 AzlC protein 16 157 6.0E-38 T 14-10-2018 IPR011606 Branched-chain amino acid transport, permease TSH58p_28805 283ef8e76d654e688965ef7d6be9ff8e 305 Gene3D G3DSA:3.40.50.720 18 192 6.1E-60 T 14-10-2018 TSH58p_28805 283ef8e76d654e688965ef7d6be9ff8e 305 Gene3D G3DSA:1.10.3660.10 193 299 7.1E-36 T 14-10-2018 TSH58p_28805 283ef8e76d654e688965ef7d6be9ff8e 305 SUPERFAMILY SSF48179 190 299 7.37E-35 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_28805 283ef8e76d654e688965ef7d6be9ff8e 305 Pfam PF02153 Prephenate dehydrogenase 32 289 5.7E-77 T 14-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 TSH58p_28805 283ef8e76d654e688965ef7d6be9ff8e 305 SUPERFAMILY SSF51735 19 185 3.65E-50 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_07675 2c6350a6f64704afd2760c7db9e3dc4d 133 Gene3D G3DSA:3.30.420.130 1 119 1.9E-32 T 14-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TSH58p_07675 2c6350a6f64704afd2760c7db9e3dc4d 133 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 11 103 4.1E-16 T 14-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TSH58p_07675 2c6350a6f64704afd2760c7db9e3dc4d 133 SUPERFAMILY SSF53146 1 118 1.83E-32 T 14-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TSH58p_07675 2c6350a6f64704afd2760c7db9e3dc4d 133 TIGRFAM TIGR02663 nifX: nitrogen fixation protein NifX 1 119 1.8E-48 T 14-10-2018 IPR013480 Nitrogen fixation protein NifX GO:0009399|GO:0051188|GO:0051540 TSH58p_00920 9647adb6efdf107a887494ed1364cbb3 223 Pfam PF07484 Phage Tail Collar Domain 6 61 1.4E-19 T 14-10-2018 IPR011083 Phage tail collar domain TSH58p_00920 9647adb6efdf107a887494ed1364cbb3 223 Gene3D G3DSA:3.90.1340.10 1 58 6.2E-13 T 14-10-2018 IPR037053 Phage tail collar domain superfamily TSH58p_00920 9647adb6efdf107a887494ed1364cbb3 223 SUPERFAMILY SSF88874 2 213 1.44E-28 T 14-10-2018 TSH58p_08050 a4b36fef6c74a3faeb9d8725cbba4e07 771 SUPERFAMILY SSF52540 171 427 1.66E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_08050 a4b36fef6c74a3faeb9d8725cbba4e07 771 Pfam PF07724 AAA domain (Cdc48 subfamily) 490 651 4.5E-46 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSH58p_08050 a4b36fef6c74a3faeb9d8725cbba4e07 771 SUPERFAMILY SSF52540 441 742 2.53E-75 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_08050 a4b36fef6c74a3faeb9d8725cbba4e07 771 Gene3D G3DSA:3.40.50.300 443 655 3.1E-78 T 14-10-2018 TSH58p_08050 a4b36fef6c74a3faeb9d8725cbba4e07 771 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 537 555 5.5E-37 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 TSH58p_08050 a4b36fef6c74a3faeb9d8725cbba4e07 771 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 599 613 5.5E-37 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 TSH58p_08050 a4b36fef6c74a3faeb9d8725cbba4e07 771 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 566 584 5.5E-37 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 TSH58p_08050 a4b36fef6c74a3faeb9d8725cbba4e07 771 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 495 513 5.5E-37 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 TSH58p_08050 a4b36fef6c74a3faeb9d8725cbba4e07 771 Gene3D G3DSA:3.40.50.300 161 354 4.4E-65 T 14-10-2018 TSH58p_08050 a4b36fef6c74a3faeb9d8725cbba4e07 771 Gene3D G3DSA:1.10.1780.10 1 142 8.7E-40 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 TSH58p_08050 a4b36fef6c74a3faeb9d8725cbba4e07 771 SUPERFAMILY SSF81923 1 141 1.44E-58 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 TSH58p_08050 a4b36fef6c74a3faeb9d8725cbba4e07 771 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 522 540 - T 14-10-2018 IPR028299 ClpA/B, conserved site 2 TSH58p_08050 a4b36fef6c74a3faeb9d8725cbba4e07 771 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 3 738 0.0 T 14-10-2018 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0016887|GO:0043335 TSH58p_08050 a4b36fef6c74a3faeb9d8725cbba4e07 771 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 215 346 1.4E-11 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSH58p_08050 a4b36fef6c74a3faeb9d8725cbba4e07 771 SMART SM00382 210 356 7.8E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_08050 a4b36fef6c74a3faeb9d8725cbba4e07 771 SMART SM00382 491 627 4.2E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_08050 a4b36fef6c74a3faeb9d8725cbba4e07 771 Gene3D G3DSA:1.10.8.60 657 761 4.6E-31 T 14-10-2018 TSH58p_08050 a4b36fef6c74a3faeb9d8725cbba4e07 771 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 13 62 7.0E-12 T 14-10-2018 IPR004176 Clp, N-terminal TSH58p_08050 a4b36fef6c74a3faeb9d8725cbba4e07 771 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 657 737 4.1E-25 T 14-10-2018 IPR019489 Clp ATPase, C-terminal TSH58p_08050 a4b36fef6c74a3faeb9d8725cbba4e07 771 SMART SM01086 657 746 8.6E-38 T 14-10-2018 IPR019489 Clp ATPase, C-terminal TSH58p_08050 a4b36fef6c74a3faeb9d8725cbba4e07 771 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 306 318 - T 14-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 TSH58p_08050 a4b36fef6c74a3faeb9d8725cbba4e07 771 Gene3D G3DSA:1.10.8.60 355 442 1.7E-31 T 14-10-2018 TSH58p_01990 4d2718fe5ffc5adfa11d8cc4ac63aa8b 268 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 92 1.4E-11 T 14-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal TSH58p_01990 4d2718fe5ffc5adfa11d8cc4ac63aa8b 268 SUPERFAMILY SSF48179 155 262 8.84E-27 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_01990 4d2718fe5ffc5adfa11d8cc4ac63aa8b 268 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 261 22.934 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TSH58p_01990 4d2718fe5ffc5adfa11d8cc4ac63aa8b 268 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 1 261 2.7E-69 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TSH58p_01990 4d2718fe5ffc5adfa11d8cc4ac63aa8b 268 SUPERFAMILY SSF51735 1 152 1.4E-26 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_01990 4d2718fe5ffc5adfa11d8cc4ac63aa8b 268 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 156 261 1.6E-29 T 14-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TSH58p_01990 4d2718fe5ffc5adfa11d8cc4ac63aa8b 268 PIRSF PIRSF000193 1 264 2.7E-55 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TSH58p_01990 4d2718fe5ffc5adfa11d8cc4ac63aa8b 268 Gene3D G3DSA:3.40.50.720 1 157 9.1E-35 T 14-10-2018 TSH58p_01990 4d2718fe5ffc5adfa11d8cc4ac63aa8b 268 Gene3D G3DSA:1.10.3730.10 158 263 9.7E-34 T 14-10-2018 TSH58p_31995 e32b1669cced487d4c1ca749145d3a40 264 Pfam PF00027 Cyclic nucleotide-binding domain 6 88 1.8E-15 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_31995 e32b1669cced487d4c1ca749145d3a40 264 SMART SM00100 1 103 3.3E-4 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_31995 e32b1669cced487d4c1ca749145d3a40 264 Gene3D G3DSA:2.60.200.20 120 260 2.2E-11 T 14-10-2018 TSH58p_31995 e32b1669cced487d4c1ca749145d3a40 264 SUPERFAMILY SSF49879 160 244 4.97E-12 T 14-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 TSH58p_31995 e32b1669cced487d4c1ca749145d3a40 264 SMART SM00240 168 230 0.0027 T 14-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TSH58p_31995 e32b1669cced487d4c1ca749145d3a40 264 SUPERFAMILY SSF51206 3 113 2.49E-21 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like TSH58p_31995 e32b1669cced487d4c1ca749145d3a40 264 Gene3D G3DSA:2.60.120.10 1 119 3.3E-22 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_31995 e32b1669cced487d4c1ca749145d3a40 264 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 53 70 - T 14-10-2018 IPR018488 Cyclic nucleotide-binding, conserved site TSH58p_31995 e32b1669cced487d4c1ca749145d3a40 264 Pfam PF00498 FHA domain 174 241 7.6E-8 T 14-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TSH58p_20450 bcfc0d78bda8192257ec1c6a58f11859 748 Pfam PF00593 TonB dependent receptor 209 746 3.6E-24 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel TSH58p_20450 bcfc0d78bda8192257ec1c6a58f11859 748 Gene3D G3DSA:2.170.130.10 68 180 2.3E-11 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily TSH58p_20450 bcfc0d78bda8192257ec1c6a58f11859 748 SUPERFAMILY SSF56935 74 748 2.86E-80 T 14-10-2018 TSH58p_20450 bcfc0d78bda8192257ec1c6a58f11859 748 Pfam PF07715 TonB-dependent Receptor Plug Domain 78 173 5.3E-10 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain TSH58p_20450 bcfc0d78bda8192257ec1c6a58f11859 748 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 731 748 - T 14-10-2018 IPR010917 TonB-dependent receptor, conserved site TSH58p_18190 74ed418452b0d213d7e7834c9cef09e7 280 SUPERFAMILY SSF53335 75 253 8.13E-25 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_18190 74ed418452b0d213d7e7834c9cef09e7 280 Gene3D G3DSA:3.40.50.150 70 258 2.7E-25 T 14-10-2018 TSH58p_18190 74ed418452b0d213d7e7834c9cef09e7 280 Pfam PF13649 Methyltransferase domain 112 204 5.0E-14 T 14-10-2018 TSH58p_02200 e6615b8ff46b68aac9b67b7ebf03fd08 308 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_02200 e6615b8ff46b68aac9b67b7ebf03fd08 308 Gene3D G3DSA:3.40.50.300 1 236 7.0E-64 T 14-10-2018 TSH58p_02200 e6615b8ff46b68aac9b67b7ebf03fd08 308 Pfam PF00005 ABC transporter 21 163 4.1E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_02200 e6615b8ff46b68aac9b67b7ebf03fd08 308 SUPERFAMILY SSF52540 2 228 1.18E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_02200 e6615b8ff46b68aac9b67b7ebf03fd08 308 SMART SM00382 30 218 4.4E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_14190 b517d842f354d03397b7f6471e7309c1 229 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_14190 b517d842f354d03397b7f6471e7309c1 229 SMART SM00421 152 209 1.0E-23 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_14190 b517d842f354d03397b7f6471e7309c1 229 Pfam PF00072 Response regulator receiver domain 6 118 1.6E-11 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_14190 b517d842f354d03397b7f6471e7309c1 229 SUPERFAMILY SSF46894 145 214 2.99E-20 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_14190 b517d842f354d03397b7f6471e7309c1 229 Gene3D G3DSA:3.40.50.12740 4 214 1.1E-47 T 14-10-2018 TSH58p_14190 b517d842f354d03397b7f6471e7309c1 229 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 1.6E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_14190 b517d842f354d03397b7f6471e7309c1 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.2E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_14190 b517d842f354d03397b7f6471e7309c1 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.2E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_14190 b517d842f354d03397b7f6471e7309c1 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.2E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_14190 b517d842f354d03397b7f6471e7309c1 229 SUPERFAMILY SSF52172 1 122 1.21E-19 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_14190 b517d842f354d03397b7f6471e7309c1 229 SMART SM00448 4 118 1.2E-6 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_04200 71ff8d8039e1c8287995a942b883aa4d 264 Gene3D G3DSA:3.30.465.10 55 168 1.2E-36 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TSH58p_04200 71ff8d8039e1c8287995a942b883aa4d 264 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 172 261 3.0E-6 T 14-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal TSH58p_04200 71ff8d8039e1c8287995a942b883aa4d 264 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 164 3.2E-49 T 14-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 TSH58p_04200 71ff8d8039e1c8287995a942b883aa4d 264 SMART SM01092 171 263 2.8E-20 T 14-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal TSH58p_04200 71ff8d8039e1c8287995a942b883aa4d 264 SUPERFAMILY SSF56176 1 165 5.01E-53 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TSH58p_04200 71ff8d8039e1c8287995a942b883aa4d 264 SUPERFAMILY SSF55447 170 261 3.01E-19 T 14-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily TSH58p_04200 71ff8d8039e1c8287995a942b883aa4d 264 Gene3D G3DSA:3.30.390.50 169 263 4.8E-12 T 14-10-2018 TSH58p_04200 71ff8d8039e1c8287995a942b883aa4d 264 Gene3D G3DSA:3.30.43.10 1 51 2.9E-16 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 TSH58p_32460 0a1c592197184ad658e4ec3fa49f2567 303 SUPERFAMILY SSF51735 2 176 9.26E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_32460 0a1c592197184ad658e4ec3fa49f2567 303 Gene3D G3DSA:1.10.1040.10 182 302 2.1E-33 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSH58p_32460 0a1c592197184ad658e4ec3fa49f2567 303 Gene3D G3DSA:3.40.50.720 4 181 2.6E-56 T 14-10-2018 TSH58p_32460 0a1c592197184ad658e4ec3fa49f2567 303 PIRSF PIRSF000105 1 302 2.7E-81 T 14-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 TSH58p_32460 0a1c592197184ad658e4ec3fa49f2567 303 SUPERFAMILY SSF48179 179 284 4.34E-20 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_32460 0a1c592197184ad658e4ec3fa49f2567 303 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 180 277 2.4E-18 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 TSH58p_32460 0a1c592197184ad658e4ec3fa49f2567 303 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 6 177 1.4E-51 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 TSH58p_25615 b72795e9410eaaf61190b58e817f9ad8 183 Gene3D G3DSA:3.30.1380.10 72 183 2.9E-14 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSH58p_25615 b72795e9410eaaf61190b58e817f9ad8 183 SUPERFAMILY SSF55166 70 180 4.97E-27 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSH58p_25615 b72795e9410eaaf61190b58e817f9ad8 183 Pfam PF05951 Bacterial protein of unknown function (DUF882) 39 180 4.9E-35 T 14-10-2018 IPR010275 Protein of unknown function DUF882 TSH58p_02305 3b42361649fb6fa1377e73ad573f2081 566 Gene3D G3DSA:3.30.70.1230 363 561 2.9E-31 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_02305 3b42361649fb6fa1377e73ad573f2081 566 SMART SM00044 332 543 1.3E-4 T 14-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 TSH58p_02305 3b42361649fb6fa1377e73ad573f2081 566 SUPERFAMILY SSF55073 365 552 4.08E-31 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_02305 3b42361649fb6fa1377e73ad573f2081 566 SUPERFAMILY SSF54292 258 345 1.04E-22 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TSH58p_02305 3b42361649fb6fa1377e73ad573f2081 566 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 370 544 4.8E-14 T 14-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 TSH58p_02305 3b42361649fb6fa1377e73ad573f2081 566 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 265 338 3.7E-12 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 TSH58p_02305 3b42361649fb6fa1377e73ad573f2081 566 SUPERFAMILY SSF81343 12 191 1.37E-11 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_02305 3b42361649fb6fa1377e73ad573f2081 566 Gene3D G3DSA:3.10.20.30 255 348 3.7E-21 T 14-10-2018 IPR012675 Beta-grasp domain superfamily TSH58p_14070 2cc1b4fcc0b9c78a96186c221a75a08f 177 Pfam PF05981 CreA protein 38 164 1.1E-43 T 14-10-2018 IPR010292 Uncharacterised protein family CreA TSH58p_30750 a73d97613be957c72807cbf98d70314c 249 Gene3D G3DSA:3.50.30.100 7 210 4.4E-51 T 14-10-2018 TSH58p_30750 a73d97613be957c72807cbf98d70314c 249 Pfam PF03737 Aldolase/RraA 45 187 3.7E-36 T 14-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein TSH58p_30750 a73d97613be957c72807cbf98d70314c 249 SUPERFAMILY SSF89562 34 196 1.83E-42 T 14-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily TSH58p_08085 29f1d3adbab7c2ebe7d9b371666c983f 621 SUPERFAMILY SSF64518 6 621 5.89E-36 T 14-10-2018 TSH58p_08085 29f1d3adbab7c2ebe7d9b371666c983f 621 Gene3D G3DSA:2.30.220.10 200 289 2.3E-6 T 14-10-2018 TSH58p_08085 29f1d3adbab7c2ebe7d9b371666c983f 621 Pfam PF00669 Bacterial flagellin N-terminal helical region 4 146 2.8E-13 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 TSH58p_08085 29f1d3adbab7c2ebe7d9b371666c983f 621 Gene3D G3DSA:1.20.58.1830 18 34 2.3E-6 T 14-10-2018 TSH58p_08085 29f1d3adbab7c2ebe7d9b371666c983f 621 Gene3D G3DSA:1.20.1330.10 46 185 2.3E-6 T 14-10-2018 TSH58p_08085 29f1d3adbab7c2ebe7d9b371666c983f 621 Gene3D G3DSA:2.170.280.10 186 378 2.3E-6 T 14-10-2018 TSH58p_12470 90277913e9abf6fa14e902e2666dec87 412 Gene3D G3DSA:3.10.20.340 284 412 1.3E-42 T 14-10-2018 TSH58p_12470 90277913e9abf6fa14e902e2666dec87 412 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 19 412 2.2E-114 T 14-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TSH58p_12470 90277913e9abf6fa14e902e2666dec87 412 Pfam PF01960 ArgJ family 24 412 3.2E-137 T 14-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TSH58p_12470 90277913e9abf6fa14e902e2666dec87 412 Gene3D G3DSA:3.60.70.12 15 283 8.0E-86 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TSH58p_12470 90277913e9abf6fa14e902e2666dec87 412 SUPERFAMILY SSF56266 19 408 1.31E-132 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TSH58p_12470 90277913e9abf6fa14e902e2666dec87 412 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 27 410 4.0E-108 T 14-10-2018 TSH58p_12470 90277913e9abf6fa14e902e2666dec87 412 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 412 149.239 T 14-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TSH58p_32480 2443b244fd0f3f90566b2b5cac8a53b2 177 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 16 177 1.6E-67 T 14-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TSH58p_32480 2443b244fd0f3f90566b2b5cac8a53b2 177 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 92 176 7.2E-39 T 14-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 TSH58p_32480 2443b244fd0f3f90566b2b5cac8a53b2 177 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 16 85 4.9E-29 T 14-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TSH58p_32480 2443b244fd0f3f90566b2b5cac8a53b2 177 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 10 177 29.534 T 14-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TSH58p_32480 2443b244fd0f3f90566b2b5cac8a53b2 177 SUPERFAMILY SSF54364 13 87 1.2E-27 T 14-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TSH58p_32480 2443b244fd0f3f90566b2b5cac8a53b2 177 Gene3D G3DSA:3.30.110.10 85 177 6.9E-39 T 14-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 TSH58p_32480 2443b244fd0f3f90566b2b5cac8a53b2 177 ProSitePatterns PS00938 Initiation factor 3 signature. 67 80 - T 14-10-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 TSH58p_32480 2443b244fd0f3f90566b2b5cac8a53b2 177 Gene3D G3DSA:3.10.20.80 11 84 7.1E-30 T 14-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TSH58p_32480 2443b244fd0f3f90566b2b5cac8a53b2 177 SUPERFAMILY SSF55200 92 176 3.27E-34 T 14-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 TSH58p_13795 d1ce0994f98f205d5b5d5cd6bdef0c60 231 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 6 213 4.1E-62 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 TSH58p_13795 d1ce0994f98f205d5b5d5cd6bdef0c60 231 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 4 226 54.98 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 TSH58p_13795 d1ce0994f98f205d5b5d5cd6bdef0c60 231 Gene3D G3DSA:3.40.50.620 3 227 4.2E-73 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_13795 d1ce0994f98f205d5b5d5cd6bdef0c60 231 Pfam PF06508 Queuosine biosynthesis protein QueC 6 220 2.1E-77 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 TSH58p_13795 d1ce0994f98f205d5b5d5cd6bdef0c60 231 SUPERFAMILY SSF52402 5 228 1.43E-61 T 14-10-2018 TSH58p_13795 d1ce0994f98f205d5b5d5cd6bdef0c60 231 PIRSF PIRSF006293 2 230 9.5E-78 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 TSH58p_09045 12cacaa4cc904dc46eede932cca2e8dd 408 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 16 393 23.289 T 14-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 TSH58p_09045 12cacaa4cc904dc46eede932cca2e8dd 408 Gene3D G3DSA:1.20.1530.10 14 395 1.8E-141 T 14-10-2018 IPR023171 Na/H antiporter domain superfamily TSH58p_09045 12cacaa4cc904dc46eede932cca2e8dd 408 Pfam PF06965 Na+/H+ antiporter 1 18 387 2.1E-139 T 14-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 TSH58p_09045 12cacaa4cc904dc46eede932cca2e8dd 408 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 19 387 3.4E-137 T 14-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 TSH58p_21960 d1848fdb5392ef5e52530015a16f68e0 126 PRINTS PR00604 Class IA and IB cytochrome C signature 99 109 3.7E-17 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_21960 d1848fdb5392ef5e52530015a16f68e0 126 PRINTS PR00604 Class IA and IB cytochrome C signature 47 62 3.7E-17 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_21960 d1848fdb5392ef5e52530015a16f68e0 126 PRINTS PR00604 Class IA and IB cytochrome C signature 80 96 3.7E-17 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_21960 d1848fdb5392ef5e52530015a16f68e0 126 PRINTS PR00604 Class IA and IB cytochrome C signature 63 73 3.7E-17 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_21960 d1848fdb5392ef5e52530015a16f68e0 126 PRINTS PR00604 Class IA and IB cytochrome C signature 116 124 3.7E-17 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_21960 d1848fdb5392ef5e52530015a16f68e0 126 PRINTS PR00604 Class IA and IB cytochrome C signature 35 42 3.7E-17 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_21960 d1848fdb5392ef5e52530015a16f68e0 126 Pfam PF00034 Cytochrome c 26 125 6.4E-8 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_21960 d1848fdb5392ef5e52530015a16f68e0 126 SUPERFAMILY SSF46626 23 124 6.35E-32 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_21960 d1848fdb5392ef5e52530015a16f68e0 126 Gene3D G3DSA:1.10.760.10 11 125 3.7E-40 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_29925 a906bed7ed0c627886993b288d714209 400 SMART SM00091 31 98 9.5E-11 T 14-10-2018 IPR000014 PAS domain TSH58p_29925 a906bed7ed0c627886993b288d714209 400 Gene3D G3DSA:1.10.287.130 159 215 2.9E-9 T 14-10-2018 TSH58p_29925 a906bed7ed0c627886993b288d714209 400 Gene3D G3DSA:3.30.450.20 34 137 4.6E-11 T 14-10-2018 TSH58p_29925 a906bed7ed0c627886993b288d714209 400 SMART SM00388 156 220 3.4E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_29925 a906bed7ed0c627886993b288d714209 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 313 327 1.3E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_29925 a906bed7ed0c627886993b288d714209 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 342 360 1.3E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_29925 a906bed7ed0c627886993b288d714209 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 378 1.3E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_29925 a906bed7ed0c627886993b288d714209 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 331 341 1.3E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_29925 a906bed7ed0c627886993b288d714209 400 Pfam PF00512 His Kinase A (phospho-acceptor) domain 159 215 3.2E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_29925 a906bed7ed0c627886993b288d714209 400 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 262 378 2.5E-17 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_29925 a906bed7ed0c627886993b288d714209 400 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 36 107 2.4E-8 T 14-10-2018 IPR000014 PAS domain TSH58p_29925 a906bed7ed0c627886993b288d714209 400 SUPERFAMILY SSF47384 151 215 6.67E-9 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_29925 a906bed7ed0c627886993b288d714209 400 Gene3D G3DSA:3.30.565.10 219 379 3.2E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_29925 a906bed7ed0c627886993b288d714209 400 SUPERFAMILY SSF55874 225 378 1.57E-33 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_29925 a906bed7ed0c627886993b288d714209 400 Pfam PF00989 PAS fold 34 136 2.3E-17 T 14-10-2018 IPR013767 PAS fold GO:0006355 TSH58p_29925 a906bed7ed0c627886993b288d714209 400 SMART SM00387 261 381 5.6E-30 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_29925 a906bed7ed0c627886993b288d714209 400 SUPERFAMILY SSF55785 36 107 6.63E-10 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_28990 9a06ee4153fa2b7ad665ffe1fb6d7ae1 263 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_28990 9a06ee4153fa2b7ad665ffe1fb6d7ae1 263 Pfam PF00005 ABC transporter 29 168 2.1E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_28990 9a06ee4153fa2b7ad665ffe1fb6d7ae1 263 SUPERFAMILY SSF52540 7 219 1.13E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_28990 9a06ee4153fa2b7ad665ffe1fb6d7ae1 263 SMART SM00382 35 216 5.6E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_28990 9a06ee4153fa2b7ad665ffe1fb6d7ae1 263 Gene3D G3DSA:3.40.50.300 4 247 1.2E-59 T 14-10-2018 TSH58p_26840 2e686b0f687946e66af0bd664e6e4777 206 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 49 8.1E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_26840 2e686b0f687946e66af0bd664e6e4777 206 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 19 33 8.1E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_26840 2e686b0f687946e66af0bd664e6e4777 206 Pfam PF07729 FCD domain 69 192 1.0E-23 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_26840 2e686b0f687946e66af0bd664e6e4777 206 SUPERFAMILY SSF48008 65 201 1.18E-22 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_26840 2e686b0f687946e66af0bd664e6e4777 206 Gene3D G3DSA:1.20.120.530 62 205 1.2E-26 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_26840 2e686b0f687946e66af0bd664e6e4777 206 SMART SM00895 69 193 4.1E-14 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_26840 2e686b0f687946e66af0bd664e6e4777 206 SMART SM00345 1 59 9.7E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_26840 2e686b0f687946e66af0bd664e6e4777 206 Pfam PF00392 Bacterial regulatory proteins, gntR family 1 59 1.0E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_26840 2e686b0f687946e66af0bd664e6e4777 206 Gene3D G3DSA:1.10.10.10 1 59 2.4E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_26840 2e686b0f687946e66af0bd664e6e4777 206 SUPERFAMILY SSF46785 1 63 3.13E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_01445 f887f7e282a640fdef858a4554996ebe 168 Gene3D G3DSA:1.10.1740.10 2 79 9.3E-8 T 14-10-2018 TSH58p_01445 f887f7e282a640fdef858a4554996ebe 168 Pfam PF08281 Sigma-70, region 4 110 162 2.2E-18 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_01445 f887f7e282a640fdef858a4554996ebe 168 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 166 5.9E-26 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TSH58p_01445 f887f7e282a640fdef858a4554996ebe 168 SUPERFAMILY SSF88659 95 166 5.67E-18 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSH58p_01445 f887f7e282a640fdef858a4554996ebe 168 Gene3D G3DSA:1.10.10.10 92 167 8.2E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_01445 f887f7e282a640fdef858a4554996ebe 168 Pfam PF04542 Sigma-70 region 2 14 78 6.6E-10 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_01445 f887f7e282a640fdef858a4554996ebe 168 SUPERFAMILY SSF88946 2 74 1.45E-12 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_06500 bbc342fa42e42b684632c91fb442b1ee 180 Hamap MF_00143 UPF0114 protein YqhA [yqhA]. 1 168 83.357 T 14-10-2018 IPR020761 Uncharacterised protein family UPF0114, bacteria TSH58p_06500 bbc342fa42e42b684632c91fb442b1ee 180 Pfam PF03350 Uncharacterized protein family, UPF0114 10 126 2.0E-39 T 14-10-2018 IPR005134 Uncharacterised protein family UPF0114 TSH58p_06500 bbc342fa42e42b684632c91fb442b1ee 180 TIGRFAM TIGR00645 HI0507: TIGR00645 family protein 3 165 5.7E-61 T 14-10-2018 IPR020761 Uncharacterised protein family UPF0114, bacteria TSH58p_12275 c3eea6cb5c4324f157b72bca067d957b 820 SUPERFAMILY SSF55785 204 319 3.49E-6 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_12275 c3eea6cb5c4324f157b72bca067d957b 820 Gene3D G3DSA:3.30.450.20 462 576 1.9E-7 T 14-10-2018 TSH58p_12275 c3eea6cb5c4324f157b72bca067d957b 820 SMART SM00091 212 278 11.0 T 14-10-2018 IPR000014 PAS domain TSH58p_12275 c3eea6cb5c4324f157b72bca067d957b 820 SMART SM00091 462 533 6.6 T 14-10-2018 IPR000014 PAS domain TSH58p_12275 c3eea6cb5c4324f157b72bca067d957b 820 SMART SM00091 333 403 38.0 T 14-10-2018 IPR000014 PAS domain TSH58p_12275 c3eea6cb5c4324f157b72bca067d957b 820 SMART SM00091 64 125 2.0 T 14-10-2018 IPR000014 PAS domain TSH58p_12275 c3eea6cb5c4324f157b72bca067d957b 820 Gene3D G3DSA:3.30.565.10 670 815 4.6E-19 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_12275 c3eea6cb5c4324f157b72bca067d957b 820 SUPERFAMILY SSF55785 446 563 1.24E-8 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_12275 c3eea6cb5c4324f157b72bca067d957b 820 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 710 812 8.8E-7 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_12275 c3eea6cb5c4324f157b72bca067d957b 820 Gene3D G3DSA:1.10.287.130 577 662 1.4E-22 T 14-10-2018 TSH58p_12275 c3eea6cb5c4324f157b72bca067d957b 820 SMART SM00387 710 813 2.2E-9 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_12275 c3eea6cb5c4324f157b72bca067d957b 820 SUPERFAMILY SSF55874 653 814 7.45E-21 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_12275 c3eea6cb5c4324f157b72bca067d957b 820 Gene3D G3DSA:3.30.450.20 203 332 3.7E-9 T 14-10-2018 TSH58p_12275 c3eea6cb5c4324f157b72bca067d957b 820 Pfam PF00512 His Kinase A (phospho-acceptor) domain 597 664 4.6E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_12275 c3eea6cb5c4324f157b72bca067d957b 820 SUPERFAMILY SSF47384 579 664 5.49E-19 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_12275 c3eea6cb5c4324f157b72bca067d957b 820 SUPERFAMILY SSF55785 317 387 2.79E-5 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_12275 c3eea6cb5c4324f157b72bca067d957b 820 SMART SM00388 596 664 1.3E-20 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_12275 c3eea6cb5c4324f157b72bca067d957b 820 Pfam PF12860 PAS fold 339 451 1.7E-11 T 14-10-2018 TSH58p_12275 c3eea6cb5c4324f157b72bca067d957b 820 Pfam PF12860 PAS fold 468 580 1.3E-9 T 14-10-2018 TSH58p_23025 ee7cf3b895879c501827aace2ca21e53 317 SUPERFAMILY SSF46689 205 252 1.25E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_23025 ee7cf3b895879c501827aace2ca21e53 317 Pfam PF01965 DJ-1/PfpI family 29 167 3.9E-16 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 TSH58p_23025 ee7cf3b895879c501827aace2ca21e53 317 Gene3D G3DSA:1.10.10.60 205 311 1.6E-26 T 14-10-2018 TSH58p_23025 ee7cf3b895879c501827aace2ca21e53 317 SMART SM00342 222 305 6.1E-24 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TSH58p_23025 ee7cf3b895879c501827aace2ca21e53 317 Pfam PF12833 Helix-turn-helix domain 228 306 2.4E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TSH58p_23025 ee7cf3b895879c501827aace2ca21e53 317 Gene3D G3DSA:3.40.50.880 1 196 3.1E-57 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_23025 ee7cf3b895879c501827aace2ca21e53 317 SUPERFAMILY SSF52317 1 188 6.96E-44 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_23025 ee7cf3b895879c501827aace2ca21e53 317 SUPERFAMILY SSF46689 258 307 8.51E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_06615 ab997fc442b2023eb7f7ac975ca73edd 189 SUPERFAMILY SSF101738 4 116 9.42E-43 T 14-10-2018 IPR036760 SspB-like superfamily TSH58p_06615 ab997fc442b2023eb7f7ac975ca73edd 189 Pfam PF04386 Stringent starvation protein B 11 181 3.5E-46 T 14-10-2018 IPR007481 Stringent starvation protein B TSH58p_06615 ab997fc442b2023eb7f7ac975ca73edd 189 Gene3D G3DSA:2.30.30.220 1 119 8.0E-49 T 14-10-2018 IPR036760 SspB-like superfamily TSH58p_13660 23e76b6d0ef90409b8a8197ef677b2e5 296 Gene3D G3DSA:3.40.1380.10 61 215 3.9E-97 T 14-10-2018 TSH58p_13660 23e76b6d0ef90409b8a8197ef677b2e5 296 Gene3D G3DSA:1.10.287.80 6 292 3.9E-97 T 14-10-2018 TSH58p_13660 23e76b6d0ef90409b8a8197ef677b2e5 296 Pfam PF00231 ATP synthase 3 295 4.1E-99 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_13660 23e76b6d0ef90409b8a8197ef677b2e5 296 PIRSF PIRSF039089 1 296 1.8E-108 T 14-10-2018 TSH58p_13660 23e76b6d0ef90409b8a8197ef677b2e5 296 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 296 33.74 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_13660 23e76b6d0ef90409b8a8197ef677b2e5 296 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 282 295 - T 14-10-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_13660 23e76b6d0ef90409b8a8197ef677b2e5 296 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 296 3.2E-108 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_13660 23e76b6d0ef90409b8a8197ef677b2e5 296 SUPERFAMILY SSF52943 2 296 2.88E-91 T 14-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_13660 23e76b6d0ef90409b8a8197ef677b2e5 296 PRINTS PR00126 ATP synthase gamma subunit signature 171 188 4.9E-33 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_13660 23e76b6d0ef90409b8a8197ef677b2e5 296 PRINTS PR00126 ATP synthase gamma subunit signature 274 295 4.9E-33 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_13660 23e76b6d0ef90409b8a8197ef677b2e5 296 PRINTS PR00126 ATP synthase gamma subunit signature 76 95 4.9E-33 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_13660 23e76b6d0ef90409b8a8197ef677b2e5 296 PRINTS PR00126 ATP synthase gamma subunit signature 243 262 4.9E-33 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_13525 343f1d92573dc6d5247c4b470a1eb895 179 Gene3D G3DSA:1.10.760.10 32 169 6.8E-43 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_13525 343f1d92573dc6d5247c4b470a1eb895 179 SUPERFAMILY SSF46626 70 173 1.72E-34 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_13525 343f1d92573dc6d5247c4b470a1eb895 179 Pfam PF00034 Cytochrome c 73 170 3.2E-9 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_13525 343f1d92573dc6d5247c4b470a1eb895 179 PRINTS PR00604 Class IA and IB cytochrome C signature 125 141 3.0E-18 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_13525 343f1d92573dc6d5247c4b470a1eb895 179 PRINTS PR00604 Class IA and IB cytochrome C signature 82 89 3.0E-18 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_13525 343f1d92573dc6d5247c4b470a1eb895 179 PRINTS PR00604 Class IA and IB cytochrome C signature 95 110 3.0E-18 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_13525 343f1d92573dc6d5247c4b470a1eb895 179 PRINTS PR00604 Class IA and IB cytochrome C signature 111 121 3.0E-18 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_13525 343f1d92573dc6d5247c4b470a1eb895 179 PRINTS PR00604 Class IA and IB cytochrome C signature 161 169 3.0E-18 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_13525 343f1d92573dc6d5247c4b470a1eb895 179 PRINTS PR00604 Class IA and IB cytochrome C signature 144 154 3.0E-18 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_01545 2026c2846b2876fb98bc0e6a904a1a28 393 SMART SM00922 153 250 6.6E-24 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal TSH58p_01545 2026c2846b2876fb98bc0e6a904a1a28 393 Gene3D G3DSA:3.20.20.120 122 389 7.9E-92 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TSH58p_01545 2026c2846b2876fb98bc0e6a904a1a28 393 Pfam PF13378 Enolase C-terminal domain-like 156 381 9.0E-66 T 14-10-2018 IPR029065 Enolase C-terminal domain-like TSH58p_01545 2026c2846b2876fb98bc0e6a904a1a28 393 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 101 126 - T 14-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 TSH58p_01545 2026c2846b2876fb98bc0e6a904a1a28 393 SUPERFAMILY SSF51604 114 388 3.41E-78 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TSH58p_01545 2026c2846b2876fb98bc0e6a904a1a28 393 SUPERFAMILY SSF54826 1 131 1.25E-32 T 14-10-2018 TSH58p_01545 2026c2846b2876fb98bc0e6a904a1a28 393 Gene3D G3DSA:3.30.390.10 1 121 1.3E-30 T 14-10-2018 IPR029017 Enolase-like, N-terminal TSH58p_01545 2026c2846b2876fb98bc0e6a904a1a28 393 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 6 126 4.0E-17 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain TSH58p_05940 1726334673d179dd84df8bfbddfb843a 422 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 314 385 1.9E-17 T 14-10-2018 IPR019489 Clp ATPase, C-terminal TSH58p_05940 1726334673d179dd84df8bfbddfb843a 422 SMART SM00994 12 51 1.7E-24 T 14-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 TSH58p_05940 1726334673d179dd84df8bfbddfb843a 422 Pfam PF07724 AAA domain (Cdc48 subfamily) 111 307 1.5E-50 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSH58p_05940 1726334673d179dd84df8bfbddfb843a 422 SUPERFAMILY SSF57716 13 48 1.18E-11 T 14-10-2018 TSH58p_05940 1726334673d179dd84df8bfbddfb843a 422 Gene3D G3DSA:1.10.8.60 313 421 2.4E-40 T 14-10-2018 TSH58p_05940 1726334673d179dd84df8bfbddfb843a 422 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 412 53.504 T 14-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 TSH58p_05940 1726334673d179dd84df8bfbddfb843a 422 Gene3D G3DSA:3.30.50.30 2 51 3.5E-24 T 14-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily TSH58p_05940 1726334673d179dd84df8bfbddfb843a 422 Pfam PF06689 ClpX C4-type zinc finger 13 50 6.0E-20 T 14-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 TSH58p_05940 1726334673d179dd84df8bfbddfb843a 422 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 10 407 9.0E-200 T 14-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 TSH58p_05940 1726334673d179dd84df8bfbddfb843a 422 SMART SM00382 110 330 3.5E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_05940 1726334673d179dd84df8bfbddfb843a 422 SMART SM01086 314 409 1.7E-35 T 14-10-2018 IPR019489 Clp ATPase, C-terminal TSH58p_05940 1726334673d179dd84df8bfbddfb843a 422 Gene3D G3DSA:3.40.50.300 57 312 3.7E-108 T 14-10-2018 TSH58p_05940 1726334673d179dd84df8bfbddfb843a 422 SUPERFAMILY SSF52540 63 389 1.59E-74 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_09480 f1b81d70319da9527844ce96b8b1099e 293 Gene3D G3DSA:3.20.20.60 1 292 3.7E-95 T 14-10-2018 TSH58p_09480 f1b81d70319da9527844ce96b8b1099e 293 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 9 223 4.0E-47 T 14-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 TSH58p_09480 f1b81d70319da9527844ce96b8b1099e 293 PIRSF PIRSF015582 1 292 4.1E-82 T 14-10-2018 IPR011206 Citrate lyase beta subunit-like TSH58p_09480 f1b81d70319da9527844ce96b8b1099e 293 SUPERFAMILY SSF51621 6 233 9.71E-68 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSH58p_23060 e523bfe4b585fb6a24b967dc92a082c8 449 TIGRFAM TIGR02426 protocat_pcaB: 3-carboxy-cis,cis-muconate cycloisomerase 12 350 8.7E-109 T 14-10-2018 IPR012789 3-carboxy-cis,cis-muconate cycloisomerase GO:0019619|GO:0047472 KEGG: 00362+5.5.1.2 TSH58p_23060 e523bfe4b585fb6a24b967dc92a082c8 449 SMART SM00998 365 444 1.7E-34 T 14-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSH58p_23060 e523bfe4b585fb6a24b967dc92a082c8 449 Pfam PF10397 Adenylosuccinate lyase C-terminus 366 443 3.5E-22 T 14-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSH58p_23060 e523bfe4b585fb6a24b967dc92a082c8 449 Gene3D G3DSA:1.10.275.10 4 106 7.0E-34 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal TSH58p_23060 e523bfe4b585fb6a24b967dc92a082c8 449 Pfam PF00206 Lyase 17 294 2.6E-42 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal TSH58p_23060 e523bfe4b585fb6a24b967dc92a082c8 449 SUPERFAMILY SSF48557 11 447 1.12E-113 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 TSH58p_23060 e523bfe4b585fb6a24b967dc92a082c8 449 PRINTS PR00145 Argininosuccinate lyase family signature 142 162 8.0E-6 T 14-10-2018 TSH58p_23060 e523bfe4b585fb6a24b967dc92a082c8 449 PRINTS PR00145 Argininosuccinate lyase family signature 277 293 8.0E-6 T 14-10-2018 TSH58p_23060 e523bfe4b585fb6a24b967dc92a082c8 449 PRINTS PR00145 Argininosuccinate lyase family signature 232 256 8.0E-6 T 14-10-2018 TSH58p_23060 e523bfe4b585fb6a24b967dc92a082c8 449 Gene3D G3DSA:1.10.40.30 364 449 1.4E-31 T 14-10-2018 TSH58p_23060 e523bfe4b585fb6a24b967dc92a082c8 449 Gene3D G3DSA:1.20.200.10 107 362 2.8E-88 T 14-10-2018 TSH58p_23060 e523bfe4b585fb6a24b967dc92a082c8 449 PRINTS PR00149 Fumarate lyase superfamily signature 232 259 3.3E-18 T 14-10-2018 IPR000362 Fumarate lyase family TSH58p_23060 e523bfe4b585fb6a24b967dc92a082c8 449 PRINTS PR00149 Fumarate lyase superfamily signature 147 165 3.3E-18 T 14-10-2018 IPR000362 Fumarate lyase family TSH58p_23060 e523bfe4b585fb6a24b967dc92a082c8 449 PRINTS PR00149 Fumarate lyase superfamily signature 277 293 3.3E-18 T 14-10-2018 IPR000362 Fumarate lyase family TSH58p_23060 e523bfe4b585fb6a24b967dc92a082c8 449 PRINTS PR00149 Fumarate lyase superfamily signature 102 120 3.3E-18 T 14-10-2018 IPR000362 Fumarate lyase family TSH58p_20765 e742b6969c51a2ee9373782c191e2e0c 365 Gene3D G3DSA:1.20.1420.20 23 365 2.5E-75 T 14-10-2018 IPR038352 Imelysin-like domain superfamily TSH58p_20765 e742b6969c51a2ee9373782c191e2e0c 365 Pfam PF09375 Imelysin 40 338 1.8E-39 T 14-10-2018 IPR018976 Imelysin-like domain TSH58p_18800 2147b7c4ddaf0115c43505cd618cc16f 259 Pfam PF03180 NLPA lipoprotein 25 259 9.4E-85 T 14-10-2018 IPR004872 Lipoprotein NlpA family TSH58p_18800 2147b7c4ddaf0115c43505cd618cc16f 259 Gene3D G3DSA:3.40.190.10 106 209 6.1E-89 T 14-10-2018 TSH58p_18800 2147b7c4ddaf0115c43505cd618cc16f 259 SUPERFAMILY SSF53850 25 259 1.2E-81 T 14-10-2018 TSH58p_18800 2147b7c4ddaf0115c43505cd618cc16f 259 PIRSF PIRSF002854 1 259 6.4E-89 T 14-10-2018 IPR004872 Lipoprotein NlpA family TSH58p_18800 2147b7c4ddaf0115c43505cd618cc16f 259 Gene3D G3DSA:3.40.190.10 25 256 6.1E-89 T 14-10-2018 TSH58p_31970 3fae33a9b09c857d3cc301b01f98e959 497 Pfam PF03553 Na+/H+ antiporter family 175 477 4.9E-40 T 14-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 TSH58p_20330 1e2d7e448d5a7353d46da6b4842931c7 250 SUPERFAMILY SSF46785 31 123 2.72E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_20330 1e2d7e448d5a7353d46da6b4842931c7 250 SMART SM00895 107 231 2.3E-20 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_20330 1e2d7e448d5a7353d46da6b4842931c7 250 Gene3D G3DSA:1.10.10.10 33 98 1.7E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_20330 1e2d7e448d5a7353d46da6b4842931c7 250 Pfam PF07729 FCD domain 111 230 5.8E-30 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_20330 1e2d7e448d5a7353d46da6b4842931c7 250 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 71 87 2.2E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_20330 1e2d7e448d5a7353d46da6b4842931c7 250 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 71 2.2E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_20330 1e2d7e448d5a7353d46da6b4842931c7 250 Gene3D G3DSA:1.20.120.530 105 240 3.7E-30 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_20330 1e2d7e448d5a7353d46da6b4842931c7 250 SUPERFAMILY SSF48008 106 235 8.11E-30 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_20330 1e2d7e448d5a7353d46da6b4842931c7 250 Pfam PF00392 Bacterial regulatory proteins, gntR family 38 97 1.7E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_20330 1e2d7e448d5a7353d46da6b4842931c7 250 SMART SM00345 39 97 1.4E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_02220 92b41f9bdb44d289fb0635b60a11189d 448 Pfam PF01425 Amidase 12 426 2.0E-110 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_02220 92b41f9bdb44d289fb0635b60a11189d 448 ProSitePatterns PS00571 Amidases signature. 135 166 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 TSH58p_02220 92b41f9bdb44d289fb0635b60a11189d 448 SUPERFAMILY SSF75304 8 445 1.11E-134 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_02220 92b41f9bdb44d289fb0635b60a11189d 448 Gene3D G3DSA:3.90.1300.10 4 446 3.4E-141 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_29995 f958e3044d25f600d74b11a0583b95ae 61 SUPERFAMILY SSF47598 5 50 2.71E-5 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TSH58p_30155 f958e3044d25f600d74b11a0583b95ae 61 SUPERFAMILY SSF47598 5 50 2.71E-5 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TSH58p_19760 42b36b657fff839574cde89e459d0836 217 Gene3D G3DSA:3.40.50.1000 13 192 1.6E-20 T 14-10-2018 IPR023214 HAD superfamily TSH58p_19760 42b36b657fff839574cde89e459d0836 217 Gene3D G3DSA:1.10.150.240 25 94 1.6E-20 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 TSH58p_19760 42b36b657fff839574cde89e459d0836 217 Pfam PF13419 Haloacid dehalogenase-like hydrolase 13 191 6.1E-14 T 14-10-2018 TSH58p_19760 42b36b657fff839574cde89e459d0836 217 SUPERFAMILY SSF56784 11 214 8.7E-27 T 14-10-2018 IPR036412 HAD-like superfamily TSH58p_31085 7ff437863e7b16db457e051f03b915ca 336 Pfam PF16220 Domain of unknown function (DUF4880) 24 65 6.7E-12 T 14-10-2018 IPR032623 FecR, N-terminal TSH58p_31085 7ff437863e7b16db457e051f03b915ca 336 Pfam PF16344 Domain of unknown function (DUF4974) 235 320 3.0E-8 T 14-10-2018 IPR032508 Protein FecR, C-terminal TSH58p_31085 7ff437863e7b16db457e051f03b915ca 336 PIRSF PIRSF018266 13 336 2.8E-84 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component TSH58p_31085 7ff437863e7b16db457e051f03b915ca 336 Gene3D G3DSA:3.55.50.30 262 335 2.7E-6 T 14-10-2018 TSH58p_31085 7ff437863e7b16db457e051f03b915ca 336 Pfam PF04773 FecR protein 126 216 9.5E-23 T 14-10-2018 IPR006860 FecR protein TSH58p_31085 7ff437863e7b16db457e051f03b915ca 336 Gene3D G3DSA:2.60.120.1440 115 252 3.5E-26 T 14-10-2018 TSH58p_28725 530649afeac67e7ba3b868cc1663307b 78 Pfam PF01206 Sulfurtransferase TusA 4 73 7.7E-18 T 14-10-2018 IPR001455 TusA-like domain TSH58p_28725 530649afeac67e7ba3b868cc1663307b 78 SUPERFAMILY SSF64307 4 74 1.27E-21 T 14-10-2018 IPR036868 TusA-like domain superfamily TSH58p_28725 530649afeac67e7ba3b868cc1663307b 78 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 6 30 - T 14-10-2018 IPR001455 TusA-like domain TSH58p_28725 530649afeac67e7ba3b868cc1663307b 78 Gene3D G3DSA:3.30.110.40 1 75 6.9E-27 T 14-10-2018 IPR036868 TusA-like domain superfamily TSH58p_29490 d0447321ff48aefa7adb1c8a328cf609 874 Gene3D G3DSA:3.30.450.20 373 490 5.3E-39 T 14-10-2018 TSH58p_29490 d0447321ff48aefa7adb1c8a328cf609 874 SUPERFAMILY SSF55785 388 501 4.49E-31 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_29490 d0447321ff48aefa7adb1c8a328cf609 874 SMART SM00388 513 578 4.8E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_29490 d0447321ff48aefa7adb1c8a328cf609 874 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 623 731 7.9E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_29490 d0447321ff48aefa7adb1c8a328cf609 874 Pfam PF00512 His Kinase A (phospho-acceptor) domain 513 578 4.4E-7 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_29490 d0447321ff48aefa7adb1c8a328cf609 874 SMART SM00448 753 866 1.2E-19 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_29490 d0447321ff48aefa7adb1c8a328cf609 874 SMART SM00086 453 493 0.0025 T 14-10-2018 IPR001610 PAC motif TSH58p_29490 d0447321ff48aefa7adb1c8a328cf609 874 SUPERFAMILY SSF52172 755 870 6.26E-21 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_29490 d0447321ff48aefa7adb1c8a328cf609 874 Pfam PF00072 Response regulator receiver domain 755 866 1.7E-12 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_29490 d0447321ff48aefa7adb1c8a328cf609 874 Gene3D G3DSA:1.10.287.130 491 576 3.4E-13 T 14-10-2018 TSH58p_29490 d0447321ff48aefa7adb1c8a328cf609 874 Gene3D G3DSA:3.30.450.20 170 297 7.1E-6 T 14-10-2018 TSH58p_29490 d0447321ff48aefa7adb1c8a328cf609 874 Gene3D G3DSA:3.30.565.10 588 740 3.1E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_29490 d0447321ff48aefa7adb1c8a328cf609 874 SMART SM00387 622 733 1.4E-28 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_29490 d0447321ff48aefa7adb1c8a328cf609 874 SMART SM00091 377 443 7.7E-12 T 14-10-2018 IPR000014 PAS domain TSH58p_29490 d0447321ff48aefa7adb1c8a328cf609 874 Gene3D G3DSA:3.40.50.2300 753 872 5.4E-20 T 14-10-2018 TSH58p_29490 d0447321ff48aefa7adb1c8a328cf609 874 SUPERFAMILY SSF47384 499 578 9.02E-12 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_29490 d0447321ff48aefa7adb1c8a328cf609 874 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 373 500 1.0E-36 T 14-10-2018 IPR000014 PAS domain TSH58p_29490 d0447321ff48aefa7adb1c8a328cf609 874 Pfam PF00989 PAS fold 380 490 7.9E-17 T 14-10-2018 IPR013767 PAS fold GO:0006355 TSH58p_29490 d0447321ff48aefa7adb1c8a328cf609 874 SUPERFAMILY SSF55874 567 737 4.85E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_29490 d0447321ff48aefa7adb1c8a328cf609 874 Pfam PF02743 Cache domain 59 281 1.1E-13 T 14-10-2018 IPR033479 Double Cache domain 1 TSH58p_29490 d0447321ff48aefa7adb1c8a328cf609 874 PRINTS PR00344 Bacterial sensor protein C-terminal signature 658 672 4.5E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_29490 d0447321ff48aefa7adb1c8a328cf609 874 PRINTS PR00344 Bacterial sensor protein C-terminal signature 676 686 4.5E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_29490 d0447321ff48aefa7adb1c8a328cf609 874 PRINTS PR00344 Bacterial sensor protein C-terminal signature 693 711 4.5E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_29490 d0447321ff48aefa7adb1c8a328cf609 874 PRINTS PR00344 Bacterial sensor protein C-terminal signature 717 730 4.5E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_30935 aa3082d395b118ec92d99359d72ef09c 298 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 169 288 2.8E-35 T 14-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 TSH58p_30935 aa3082d395b118ec92d99359d72ef09c 298 SUPERFAMILY SSF48179 168 289 2.04E-33 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_30935 aa3082d395b118ec92d99359d72ef09c 298 Gene3D G3DSA:1.10.1040.10 168 293 9.4E-38 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSH58p_30935 aa3082d395b118ec92d99359d72ef09c 298 Gene3D G3DSA:3.40.50.720 3 167 1.8E-49 T 14-10-2018 TSH58p_30935 aa3082d395b118ec92d99359d72ef09c 298 SUPERFAMILY SSF51735 7 165 3.12E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_30935 aa3082d395b118ec92d99359d72ef09c 298 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 10 23 - T 14-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 TSH58p_30935 aa3082d395b118ec92d99359d72ef09c 298 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 7 165 1.6E-41 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 TSH58p_30935 aa3082d395b118ec92d99359d72ef09c 298 PIRSF PIRSF000103 1 297 5.9E-73 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 TSH58p_13650 b693af39ce1bb1f01fc326147a19a9f5 189 Gene3D G3DSA:1.10.520.20 11 104 4.5E-19 T 14-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_13650 b693af39ce1bb1f01fc326147a19a9f5 189 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 144 163 - T 14-10-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_13650 b693af39ce1bb1f01fc326147a19a9f5 189 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 12 179 1.2E-38 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_13650 b693af39ce1bb1f01fc326147a19a9f5 189 Pfam PF00213 ATP synthase delta (OSCP) subunit 11 181 1.2E-46 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_13650 b693af39ce1bb1f01fc326147a19a9f5 189 PRINTS PR00125 ATP synthase delta subunit signature 157 175 3.4E-23 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_13650 b693af39ce1bb1f01fc326147a19a9f5 189 PRINTS PR00125 ATP synthase delta subunit signature 81 92 3.4E-23 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_13650 b693af39ce1bb1f01fc326147a19a9f5 189 PRINTS PR00125 ATP synthase delta subunit signature 92 106 3.4E-23 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_13650 b693af39ce1bb1f01fc326147a19a9f5 189 PRINTS PR00125 ATP synthase delta subunit signature 142 157 3.4E-23 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_13650 b693af39ce1bb1f01fc326147a19a9f5 189 PRINTS PR00125 ATP synthase delta subunit signature 11 30 3.4E-23 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_13650 b693af39ce1bb1f01fc326147a19a9f5 189 Hamap MF_01416 ATP synthase subunit delta [atpD]. 7 184 19.319 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_13650 b693af39ce1bb1f01fc326147a19a9f5 189 SUPERFAMILY SSF47928 10 112 6.28E-21 T 14-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_24815 a8612e3856448abef75747b90f875c78 253 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 3 230 1.2E-101 T 14-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 TSH58p_24815 a8612e3856448abef75747b90f875c78 253 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 14-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 TSH58p_24815 a8612e3856448abef75747b90f875c78 253 SUPERFAMILY SSF53254 1 226 1.0E-69 T 14-10-2018 IPR029033 Histidine phosphatase superfamily TSH58p_24815 a8612e3856448abef75747b90f875c78 253 Gene3D G3DSA:3.40.50.1240 1 237 2.6E-78 T 14-10-2018 IPR029033 Histidine phosphatase superfamily TSH58p_24815 a8612e3856448abef75747b90f875c78 253 SMART SM00855 3 189 8.3E-23 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TSH58p_24815 a8612e3856448abef75747b90f875c78 253 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 228 43.913 T 14-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 TSH58p_24815 a8612e3856448abef75747b90f875c78 253 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 144 208 5.5E-5 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TSH58p_24815 a8612e3856448abef75747b90f875c78 253 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 126 1.2E-28 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TSH58p_24815 a8612e3856448abef75747b90f875c78 253 PIRSF PIRSF000709 2 107 3.8E-4 T 14-10-2018 TSH58p_24815 a8612e3856448abef75747b90f875c78 253 PIRSF PIRSF000709 143 230 3.9 T 14-10-2018 TSH58p_20070 f882c23a2d74bc76ee6e046784eb721c 218 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 35 205 8.5E-27 T 14-10-2018 IPR003740 Uncharacterised membrane protein YitT TSH58p_22405 f67c5fe9a159ee13f15ee3e49532a652 201 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 96 195 3.2E-37 T 14-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSH58p_22405 f67c5fe9a159ee13f15ee3e49532a652 201 SUPERFAMILY SSF54719 89 199 4.84E-45 T 14-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSH58p_22405 f67c5fe9a159ee13f15ee3e49532a652 201 Gene3D G3DSA:1.10.287.990 20 86 1.6E-25 T 14-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSH58p_22405 f67c5fe9a159ee13f15ee3e49532a652 201 Gene3D G3DSA:2.40.500.20 89 201 2.3E-43 T 14-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSH58p_22405 f67c5fe9a159ee13f15ee3e49532a652 201 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 87 1.2E-31 T 14-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSH58p_22405 f67c5fe9a159ee13f15ee3e49532a652 201 PRINTS PR01703 Manganese superoxide dismutase signature 159 171 6.1E-25 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSH58p_22405 f67c5fe9a159ee13f15ee3e49532a652 201 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 6.1E-25 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSH58p_22405 f67c5fe9a159ee13f15ee3e49532a652 201 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 6.1E-25 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSH58p_22405 f67c5fe9a159ee13f15ee3e49532a652 201 PRINTS PR01703 Manganese superoxide dismutase signature 123 131 6.1E-25 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSH58p_22405 f67c5fe9a159ee13f15ee3e49532a652 201 PRINTS PR01703 Manganese superoxide dismutase signature 70 83 6.1E-25 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSH58p_22405 f67c5fe9a159ee13f15ee3e49532a652 201 SUPERFAMILY SSF46609 1 87 9.95E-36 T 14-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSH58p_22405 f67c5fe9a159ee13f15ee3e49532a652 201 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 161 168 - T 14-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSH58p_22405 f67c5fe9a159ee13f15ee3e49532a652 201 PIRSF PIRSF000349 1 201 2.2E-84 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSH58p_29400 4efeb76b5fcc07bfe30cc61508228f4f 136 ProSitePatterns PS00550 Hemerythrin family signature. 58 81 - T 14-10-2018 IPR016131 Haemerythrin, iron-binding site GO:0046872 TSH58p_29400 4efeb76b5fcc07bfe30cc61508228f4f 136 Gene3D G3DSA:1.20.120.50 2 136 1.3E-41 T 14-10-2018 IPR035938 Hemerythrin-like superfamily TSH58p_29400 4efeb76b5fcc07bfe30cc61508228f4f 136 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 6 130 1.1E-39 T 14-10-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 TSH58p_29400 4efeb76b5fcc07bfe30cc61508228f4f 136 SUPERFAMILY SSF47188 1 130 1.28E-35 T 14-10-2018 IPR035938 Hemerythrin-like superfamily TSH58p_29400 4efeb76b5fcc07bfe30cc61508228f4f 136 Pfam PF01814 Hemerythrin HHE cation binding domain 13 130 1.2E-15 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 TSH58p_03000 b2cd5f895d4324d4ac211bb505564219 471 ProSitePatterns PS00571 Amidases signature. 155 186 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 TSH58p_03000 b2cd5f895d4324d4ac211bb505564219 471 SUPERFAMILY SSF75304 6 468 2.62E-132 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_03000 b2cd5f895d4324d4ac211bb505564219 471 Pfam PF01425 Amidase 27 451 7.7E-107 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_03000 b2cd5f895d4324d4ac211bb505564219 471 Gene3D G3DSA:3.90.1300.10 2 469 4.4E-138 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_06055 3dd75bc5f11b460443e4808aa4d0279c 324 PIRSF PIRSF018005 2 323 3.5E-119 T 14-10-2018 IPR017804 Methyltransferase EgtD-like GO:0008168 TSH58p_06055 3dd75bc5f11b460443e4808aa4d0279c 324 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 22 320 4.5E-125 T 14-10-2018 IPR035094 Histidine N-alpha-methyltransferase KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 TSH58p_06055 3dd75bc5f11b460443e4808aa4d0279c 324 Gene3D G3DSA:3.40.50.150 48 224 2.1E-49 T 14-10-2018 TSH58p_06055 3dd75bc5f11b460443e4808aa4d0279c 324 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 22 321 6.6E-111 T 14-10-2018 IPR019257 Histidine-specific methyltransferase, SAM-dependent TSH58p_06055 3dd75bc5f11b460443e4808aa4d0279c 324 SUPERFAMILY SSF53335 67 314 2.64E-9 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_13205 14059515e3679dbbd5425020ba49b904 245 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 5 239 1.9E-54 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSH58p_13205 14059515e3679dbbd5425020ba49b904 245 Pfam PF01416 tRNA pseudouridine synthase 144 245 5.5E-31 T 14-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSH58p_13205 14059515e3679dbbd5425020ba49b904 245 Pfam PF01416 tRNA pseudouridine synthase 9 103 5.7E-10 T 14-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSH58p_13205 14059515e3679dbbd5425020ba49b904 245 PIRSF PIRSF001430 1 245 5.7E-68 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSH58p_13205 14059515e3679dbbd5425020ba49b904 245 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 245 33.823 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSH58p_13205 14059515e3679dbbd5425020ba49b904 245 Gene3D G3DSA:3.30.70.660 108 243 3.5E-46 T 14-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 TSH58p_13205 14059515e3679dbbd5425020ba49b904 245 SUPERFAMILY SSF55120 1 245 1.25E-81 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSH58p_13205 14059515e3679dbbd5425020ba49b904 245 Gene3D G3DSA:3.30.70.580 1 106 8.9E-33 T 14-10-2018 TSH58p_17120 624bea1920f720b4f3f691112bdf083f 264 SUPERFAMILY SSF46785 155 231 3.69E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_17120 624bea1920f720b4f3f691112bdf083f 264 Pfam PF13545 Crp-like helix-turn-helix domain 157 230 1.5E-14 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_17120 624bea1920f720b4f3f691112bdf083f 264 Pfam PF00027 Cyclic nucleotide-binding domain 47 123 9.4E-7 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_17120 624bea1920f720b4f3f691112bdf083f 264 Gene3D G3DSA:1.10.10.10 154 238 5.4E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_17120 624bea1920f720b4f3f691112bdf083f 264 SUPERFAMILY SSF51206 18 151 1.7E-13 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like TSH58p_17120 624bea1920f720b4f3f691112bdf083f 264 Gene3D G3DSA:2.60.120.10 37 153 6.4E-17 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_17120 624bea1920f720b4f3f691112bdf083f 264 SMART SM00419 177 225 3.0E-7 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_19160 921adfd01e6b2fd01099eba35774ebe3 365 Pfam PF01312 FlhB HrpN YscU SpaS Family 9 350 2.4E-113 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 TSH58p_19160 921adfd01e6b2fd01099eba35774ebe3 365 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 211 229 1.1E-40 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 TSH58p_19160 921adfd01e6b2fd01099eba35774ebe3 365 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 11 33 1.1E-40 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 TSH58p_19160 921adfd01e6b2fd01099eba35774ebe3 365 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 231 248 1.1E-40 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 TSH58p_19160 921adfd01e6b2fd01099eba35774ebe3 365 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 275 290 1.1E-40 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 TSH58p_19160 921adfd01e6b2fd01099eba35774ebe3 365 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 305 326 1.1E-40 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 TSH58p_19160 921adfd01e6b2fd01099eba35774ebe3 365 Gene3D G3DSA:3.40.1690.10 221 359 3.3E-55 T 14-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal TSH58p_19160 921adfd01e6b2fd01099eba35774ebe3 365 SUPERFAMILY SSF160544 255 355 1.14E-39 T 14-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal TSH58p_19160 921adfd01e6b2fd01099eba35774ebe3 365 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 9 355 2.8E-106 T 14-10-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 TSH58p_22815 8a01f9a119ff54bc5ca9b2469655d53c 185 Pfam PF08445 FR47-like protein 92 148 2.8E-12 T 14-10-2018 IPR013653 FR47-like GO:0016747 TSH58p_22815 8a01f9a119ff54bc5ca9b2469655d53c 185 SUPERFAMILY SSF55729 5 169 4.61E-24 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_22815 8a01f9a119ff54bc5ca9b2469655d53c 185 Gene3D G3DSA:3.40.630.30 6 172 5.6E-37 T 14-10-2018 TSH58p_23440 ce3082474404dc7dd072609f58bde6f4 1051 Gene3D G3DSA:1.20.1640.10 513 1028 9.2E-234 T 14-10-2018 TSH58p_23440 ce3082474404dc7dd072609f58bde6f4 1051 SUPERFAMILY SSF82866 792 1032 2.88E-36 T 14-10-2018 TSH58p_23440 ce3082474404dc7dd072609f58bde6f4 1051 SUPERFAMILY SSF82693 38 127 2.27E-16 T 14-10-2018 TSH58p_23440 ce3082474404dc7dd072609f58bde6f4 1051 SUPERFAMILY SSF82693 151 310 6.28E-11 T 14-10-2018 TSH58p_23440 ce3082474404dc7dd072609f58bde6f4 1051 Gene3D G3DSA:3.30.2090.10 708 796 9.2E-234 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_23440 ce3082474404dc7dd072609f58bde6f4 1051 Gene3D G3DSA:3.30.70.1440 654 855 9.2E-234 T 14-10-2018 TSH58p_23440 ce3082474404dc7dd072609f58bde6f4 1051 Gene3D G3DSA:3.30.70.1320 131 327 9.2E-234 T 14-10-2018 TSH58p_23440 ce3082474404dc7dd072609f58bde6f4 1051 Gene3D G3DSA:3.30.70.1430 555 653 9.2E-234 T 14-10-2018 TSH58p_23440 ce3082474404dc7dd072609f58bde6f4 1051 Pfam PF00873 AcrB/AcrD/AcrF family 1 1029 1.2E-183 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_23440 ce3082474404dc7dd072609f58bde6f4 1051 Gene3D G3DSA:3.30.70.1430 38 804 9.2E-234 T 14-10-2018 TSH58p_23440 ce3082474404dc7dd072609f58bde6f4 1051 SUPERFAMILY SSF82866 291 491 8.24E-35 T 14-10-2018 TSH58p_23440 ce3082474404dc7dd072609f58bde6f4 1051 SUPERFAMILY SSF82714 185 265 3.27E-14 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_23440 ce3082474404dc7dd072609f58bde6f4 1051 PRINTS PR00702 Acriflavin resistance protein family signature 333 356 1.9E-41 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_23440 ce3082474404dc7dd072609f58bde6f4 1051 PRINTS PR00702 Acriflavin resistance protein family signature 538 555 1.9E-41 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_23440 ce3082474404dc7dd072609f58bde6f4 1051 PRINTS PR00702 Acriflavin resistance protein family signature 466 489 1.9E-41 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_23440 ce3082474404dc7dd072609f58bde6f4 1051 PRINTS PR00702 Acriflavin resistance protein family signature 360 381 1.9E-41 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_23440 ce3082474404dc7dd072609f58bde6f4 1051 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 1.9E-41 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_23440 ce3082474404dc7dd072609f58bde6f4 1051 PRINTS PR00702 Acriflavin resistance protein family signature 388 412 1.9E-41 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_23440 ce3082474404dc7dd072609f58bde6f4 1051 PRINTS PR00702 Acriflavin resistance protein family signature 441 464 1.9E-41 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_23440 ce3082474404dc7dd072609f58bde6f4 1051 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 1.9E-41 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_23440 ce3082474404dc7dd072609f58bde6f4 1051 SUPERFAMILY SSF82714 707 793 1.44E-10 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_23440 ce3082474404dc7dd072609f58bde6f4 1051 Gene3D G3DSA:1.20.1640.10 8 512 9.2E-234 T 14-10-2018 TSH58p_23440 ce3082474404dc7dd072609f58bde6f4 1051 Gene3D G3DSA:3.30.2090.10 181 272 9.2E-234 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_01400 bcd582603334e21f348fd2b38c2ec0f4 311 Pfam PF00676 Dehydrogenase E1 component 1 291 5.4E-68 T 14-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 TSH58p_01400 bcd582603334e21f348fd2b38c2ec0f4 311 SUPERFAMILY SSF52518 1 304 3.23E-85 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_01400 bcd582603334e21f348fd2b38c2ec0f4 311 Gene3D G3DSA:3.40.50.970 1 309 3.4E-105 T 14-10-2018 TSH58p_16670 fa3a0110960c6d49855d69a4b7acb75e 257 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 87 100 - T 14-10-2018 IPR020583 Inositol monophosphatase, metal-binding site TSH58p_16670 fa3a0110960c6d49855d69a4b7acb75e 257 Hamap MF_02095 3'(2'),5'-bisphosphate nucleotidase CysQ [cysQ]. 9 257 40.835 T 14-10-2018 IPR006240 3'(2'),5'-bisphosphate nucleotidase CysQ GO:0000287|GO:0006790|GO:0008441 KEGG: 00920+3.1.3.7 TSH58p_16670 fa3a0110960c6d49855d69a4b7acb75e 257 TIGRFAM TIGR01331 bisphos_cysQ: 3'(2'),5'-bisphosphate nucleotidase 9 255 1.2E-86 T 14-10-2018 IPR006240 3'(2'),5'-bisphosphate nucleotidase CysQ GO:0000287|GO:0006790|GO:0008441 KEGG: 00920+3.1.3.7 TSH58p_16670 fa3a0110960c6d49855d69a4b7acb75e 257 Pfam PF00459 Inositol monophosphatase family 15 248 8.6E-49 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_16670 fa3a0110960c6d49855d69a4b7acb75e 257 Gene3D G3DSA:3.40.190.80 157 256 9.9E-33 T 14-10-2018 TSH58p_16670 fa3a0110960c6d49855d69a4b7acb75e 257 SUPERFAMILY SSF56655 9 253 1.31E-67 T 14-10-2018 TSH58p_16670 fa3a0110960c6d49855d69a4b7acb75e 257 PRINTS PR00377 Inositol monophosphatase superfamily signature 41 61 7.1E-12 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_16670 fa3a0110960c6d49855d69a4b7acb75e 257 PRINTS PR00377 Inositol monophosphatase superfamily signature 87 103 7.1E-12 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_16670 fa3a0110960c6d49855d69a4b7acb75e 257 PRINTS PR00377 Inositol monophosphatase superfamily signature 213 237 7.1E-12 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_16670 fa3a0110960c6d49855d69a4b7acb75e 257 PRINTS PR00377 Inositol monophosphatase superfamily signature 63 79 7.1E-12 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_16670 fa3a0110960c6d49855d69a4b7acb75e 257 Gene3D G3DSA:3.30.540.10 7 149 1.2E-39 T 14-10-2018 TSH58p_16670 fa3a0110960c6d49855d69a4b7acb75e 257 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 216 230 - T 14-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 TSH58p_21185 94a771a1c575254342be352f4ffd6233 394 Gene3D G3DSA:2.160.20.100 241 336 4.3E-22 T 14-10-2018 TSH58p_21185 94a771a1c575254342be352f4ffd6233 394 SUPERFAMILY SSF141571 251 386 4.84E-30 T 14-10-2018 TSH58p_21185 94a771a1c575254342be352f4ffd6233 394 Gene3D G3DSA:2.160.20.100 128 237 4.5E-16 T 14-10-2018 TSH58p_21185 94a771a1c575254342be352f4ffd6233 394 SUPERFAMILY SSF141571 134 221 1.09E-16 T 14-10-2018 TSH58p_21185 94a771a1c575254342be352f4ffd6233 394 Gene3D G3DSA:2.160.20.100 337 390 2.6E-8 T 14-10-2018 TSH58p_21185 94a771a1c575254342be352f4ffd6233 394 Pfam PF00805 Pentapeptide repeats (8 copies) 294 327 6.7E-11 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_21185 94a771a1c575254342be352f4ffd6233 394 Pfam PF00805 Pentapeptide repeats (8 copies) 81 114 1.9E-8 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_21185 94a771a1c575254342be352f4ffd6233 394 Pfam PF00805 Pentapeptide repeats (8 copies) 144 181 2.0E-10 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_21185 94a771a1c575254342be352f4ffd6233 394 Pfam PF00805 Pentapeptide repeats (8 copies) 341 370 1.5E-6 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_21185 94a771a1c575254342be352f4ffd6233 394 Pfam PF00805 Pentapeptide repeats (8 copies) 255 292 4.0E-4 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_21185 94a771a1c575254342be352f4ffd6233 394 Pfam PF00805 Pentapeptide repeats (8 copies) 43 79 5.9E-10 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_21185 94a771a1c575254342be352f4ffd6233 394 Gene3D G3DSA:2.160.20.80 25 126 1.9E-26 T 14-10-2018 TSH58p_21185 94a771a1c575254342be352f4ffd6233 394 SUPERFAMILY SSF141571 31 122 5.76E-24 T 14-10-2018 TSH58p_30020 23387741a548a1735b3cba6962191760 440 SUPERFAMILY SSF110849 92 202 2.09E-5 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 SUPERFAMILY SSF82693 675 896 2.33E-9 T 14-10-2018 TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 SUPERFAMILY SSF82693 140 328 1.22E-21 T 14-10-2018 TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 Gene3D G3DSA:1.20.1640.10 14 511 2.1E-213 T 14-10-2018 TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 SUPERFAMILY SSF82866 876 1073 5.75E-41 T 14-10-2018 TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 Gene3D G3DSA:1.20.1640.10 512 570 2.1E-213 T 14-10-2018 TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 Gene3D G3DSA:1.20.1640.10 911 1068 3.0E-67 T 14-10-2018 TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 SUPERFAMILY SSF82693 44 138 1.03E-22 T 14-10-2018 TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 Gene3D G3DSA:3.30.70.1440 861 910 3.0E-67 T 14-10-2018 TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 Gene3D G3DSA:3.30.2090.10 183 273 2.1E-213 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 Gene3D G3DSA:3.30.70.1440 664 824 2.1E-213 T 14-10-2018 TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 SUPERFAMILY SSF82714 187 270 5.89E-18 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 Gene3D G3DSA:3.30.70.1430 44 812 2.1E-213 T 14-10-2018 TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 Pfam PF00873 AcrB/AcrD/AcrF family 10 1071 0.0 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 PRINTS PR00702 Acriflavin resistance protein family signature 619 633 1.8E-78 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 PRINTS PR00702 Acriflavin resistance protein family signature 14 38 1.8E-78 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 PRINTS PR00702 Acriflavin resistance protein family signature 389 413 1.8E-78 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 PRINTS PR00702 Acriflavin resistance protein family signature 42 60 1.8E-78 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 PRINTS PR00702 Acriflavin resistance protein family signature 361 382 1.8E-78 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 PRINTS PR00702 Acriflavin resistance protein family signature 334 357 1.8E-78 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 PRINTS PR00702 Acriflavin resistance protein family signature 442 465 1.8E-78 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 PRINTS PR00702 Acriflavin resistance protein family signature 467 490 1.8E-78 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 PRINTS PR00702 Acriflavin resistance protein family signature 556 573 1.8E-78 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 Gene3D G3DSA:3.30.70.1320 139 330 2.1E-213 T 14-10-2018 TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 Gene3D G3DSA:3.30.70.1430 571 663 2.1E-213 T 14-10-2018 TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 Gene3D G3DSA:3.30.2090.10 715 804 2.1E-213 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 Gene3D G3DSA:3.30.2090.10 833 852 3.0E-67 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 SUPERFAMILY SSF82866 295 495 1.83E-48 T 14-10-2018 TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 SUPERFAMILY SSF82693 569 662 2.09E-14 T 14-10-2018 TSH58p_02360 82eb7c7a86db98cd5d9024b97d478079 1091 SUPERFAMILY SSF82714 718 788 4.19E-13 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_15465 bfb54d9128d652b7db48dda9f022dabb 221 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 22 218 9.1E-92 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 TSH58p_15465 bfb54d9128d652b7db48dda9f022dabb 221 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 147 162 - T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 TSH58p_15465 bfb54d9128d652b7db48dda9f022dabb 221 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 195 207 - T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 TSH58p_15465 bfb54d9128d652b7db48dda9f022dabb 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 208 218 3.3E-26 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 TSH58p_15465 bfb54d9128d652b7db48dda9f022dabb 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 118 130 3.3E-26 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 TSH58p_15465 bfb54d9128d652b7db48dda9f022dabb 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 140 152 3.3E-26 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 TSH58p_15465 bfb54d9128d652b7db48dda9f022dabb 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 18 27 3.3E-26 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 TSH58p_15465 bfb54d9128d652b7db48dda9f022dabb 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 90 104 3.3E-26 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 TSH58p_15465 bfb54d9128d652b7db48dda9f022dabb 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 78 90 3.3E-26 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 TSH58p_15465 bfb54d9128d652b7db48dda9f022dabb 221 Pfam PF00813 FliP family 22 214 3.2E-82 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 TSH58p_15465 bfb54d9128d652b7db48dda9f022dabb 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 59 78 8.9E-67 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 TSH58p_15465 bfb54d9128d652b7db48dda9f022dabb 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 168 189 8.9E-67 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 TSH58p_15465 bfb54d9128d652b7db48dda9f022dabb 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 20 39 8.9E-67 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 TSH58p_15465 bfb54d9128d652b7db48dda9f022dabb 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 147 167 8.9E-67 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 TSH58p_15465 bfb54d9128d652b7db48dda9f022dabb 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 39 59 8.9E-67 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 TSH58p_15465 bfb54d9128d652b7db48dda9f022dabb 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 192 217 8.9E-67 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 TSH58p_02350 bf9065ddd1466b02d03a82fa7381fbdf 557 Pfam PF05199 GMC oxidoreductase 405 534 4.3E-23 T 14-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 TSH58p_02350 bf9065ddd1466b02d03a82fa7381fbdf 557 Gene3D G3DSA:3.50.50.60 421 546 8.2E-16 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_02350 bf9065ddd1466b02d03a82fa7381fbdf 557 Pfam PF01266 FAD dependent oxidoreductase 17 231 4.2E-8 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TSH58p_02350 bf9065ddd1466b02d03a82fa7381fbdf 557 SUPERFAMILY SSF51905 15 544 9.18E-46 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_21210 f00af066acc216d78ad6287d9b371ffa 289 Gene3D G3DSA:3.90.550.10 1 289 2.2E-86 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_21210 f00af066acc216d78ad6287d9b371ffa 289 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 5 266 3.8E-105 T 14-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 TSH58p_21210 f00af066acc216d78ad6287d9b371ffa 289 SUPERFAMILY SSF53448 6 277 8.79E-61 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_21210 f00af066acc216d78ad6287d9b371ffa 289 Pfam PF00483 Nucleotidyl transferase 13 267 6.7E-25 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TSH58p_22995 ee4121b18ec31d1bd9a66a20dd6902ac 1167 SUPERFAMILY SSF55874 731 894 7.07E-44 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_22995 ee4121b18ec31d1bd9a66a20dd6902ac 1167 SMART SM00388 675 741 5.9E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_22995 ee4121b18ec31d1bd9a66a20dd6902ac 1167 Pfam PF00512 His Kinase A (phospho-acceptor) domain 676 741 2.5E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_22995 ee4121b18ec31d1bd9a66a20dd6902ac 1167 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 788 894 8.6E-25 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_22995 ee4121b18ec31d1bd9a66a20dd6902ac 1167 PRINTS PR00344 Bacterial sensor protein C-terminal signature 858 876 3.7E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_22995 ee4121b18ec31d1bd9a66a20dd6902ac 1167 PRINTS PR00344 Bacterial sensor protein C-terminal signature 882 895 3.7E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_22995 ee4121b18ec31d1bd9a66a20dd6902ac 1167 PRINTS PR00344 Bacterial sensor protein C-terminal signature 824 838 3.7E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_22995 ee4121b18ec31d1bd9a66a20dd6902ac 1167 PRINTS PR00344 Bacterial sensor protein C-terminal signature 842 852 3.7E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_22995 ee4121b18ec31d1bd9a66a20dd6902ac 1167 Gene3D G3DSA:3.30.565.10 740 899 2.1E-46 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_22995 ee4121b18ec31d1bd9a66a20dd6902ac 1167 Pfam PF00072 Response regulator receiver domain 922 1017 1.2E-17 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_22995 ee4121b18ec31d1bd9a66a20dd6902ac 1167 SMART SM00448 920 1038 1.6E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_22995 ee4121b18ec31d1bd9a66a20dd6902ac 1167 SUPERFAMILY SSF47384 661 742 1.26E-17 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_22995 ee4121b18ec31d1bd9a66a20dd6902ac 1167 Gene3D G3DSA:3.40.50.12740 920 1122 5.2E-27 T 14-10-2018 TSH58p_22995 ee4121b18ec31d1bd9a66a20dd6902ac 1167 Gene3D G3DSA:1.10.4160.10 18 474 1.0E-21 T 14-10-2018 IPR038271 Purine-cytosine permease superfamily TSH58p_22995 ee4121b18ec31d1bd9a66a20dd6902ac 1167 SMART SM00387 788 898 3.6E-36 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_22995 ee4121b18ec31d1bd9a66a20dd6902ac 1167 Gene3D G3DSA:1.10.287.130 636 739 9.0E-21 T 14-10-2018 TSH58p_22995 ee4121b18ec31d1bd9a66a20dd6902ac 1167 SUPERFAMILY SSF52172 918 1045 3.7E-28 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_04055 85c9ac34b6a8442e4bee1807c3b4800f 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_04055 85c9ac34b6a8442e4bee1807c3b4800f 245 SUPERFAMILY SSF51735 6 244 5.89E-85 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_04055 85c9ac34b6a8442e4bee1807c3b4800f 245 Gene3D G3DSA:3.40.50.720 1 245 9.8E-85 T 14-10-2018 TSH58p_04055 85c9ac34b6a8442e4bee1807c3b4800f 245 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 9 243 2.7E-96 T 14-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 TSH58p_04055 85c9ac34b6a8442e4bee1807c3b4800f 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 6.5E-47 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_04055 85c9ac34b6a8442e4bee1807c3b4800f 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 6.5E-47 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_04055 85c9ac34b6a8442e4bee1807c3b4800f 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 6.5E-47 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_04055 85c9ac34b6a8442e4bee1807c3b4800f 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 6.5E-47 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_04055 85c9ac34b6a8442e4bee1807c3b4800f 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 6.5E-47 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_04055 85c9ac34b6a8442e4bee1807c3b4800f 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.5E-47 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_04055 85c9ac34b6a8442e4bee1807c3b4800f 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 183 1.1E-5 T 14-10-2018 TSH58p_04055 85c9ac34b6a8442e4bee1807c3b4800f 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 242 4.2E-64 T 14-10-2018 TSH58p_04055 85c9ac34b6a8442e4bee1807c3b4800f 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 3.3E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_04055 85c9ac34b6a8442e4bee1807c3b4800f 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 3.3E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_04055 85c9ac34b6a8442e4bee1807c3b4800f 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 3.3E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00120 fcf3ae8109784e56f45140d9b1685e14 140 TIGRFAM TIGR02803 ExbD_1: TonB system transport protein ExbD 15 135 8.2E-63 T 14-10-2018 IPR014170 TonB system transport protein ExbD type-1 GO:0016020|GO:0055085 TSH58p_00120 fcf3ae8109784e56f45140d9b1685e14 140 Pfam PF02472 Biopolymer transport protein ExbD/TolR 13 132 2.3E-27 T 14-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 TSH58p_00120 fcf3ae8109784e56f45140d9b1685e14 140 Gene3D G3DSA:3.30.420.270 62 131 1.3E-24 T 14-10-2018 TSH58p_29375 fe0d362d4fafe8e588d8f8a87e1c0eeb 336 SUPERFAMILY SSF161098 92 319 7.19E-17 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_29375 fe0d362d4fafe8e588d8f8a87e1c0eeb 336 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 333 7.1E-48 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_22025 534adf8ad6ed6c2e74e63d8e09c3ef2c 417 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 18 395 7.8E-64 T 14-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 TSH58p_22025 534adf8ad6ed6c2e74e63d8e09c3ef2c 417 Gene3D G3DSA:1.20.1720.10 18 398 2.3E-94 T 14-10-2018 TSH58p_22025 534adf8ad6ed6c2e74e63d8e09c3ef2c 417 SUPERFAMILY SSF103473 19 398 1.96E-56 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_22025 534adf8ad6ed6c2e74e63d8e09c3ef2c 417 Pfam PF07690 Major Facilitator Superfamily 23 366 2.3E-42 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_13050 2cc3e381a2518a362a9161ebb479fd65 322 SUPERFAMILY SSF103481 41 142 3.4E-5 T 14-10-2018 TSH58p_13050 2cc3e381a2518a362a9161ebb479fd65 322 Pfam PF00892 EamA-like transporter family 6 115 2.3E-8 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_08845 2eb3c77197123c7b847c46115b3e0dd2 432 SMART SM01204 286 417 6.2E-33 T 14-10-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 TSH58p_08845 2eb3c77197123c7b847c46115b3e0dd2 432 Pfam PF08495 FIST N domain 83 283 3.7E-32 T 14-10-2018 IPR013702 FIST domain, N-terminal TSH58p_08845 2eb3c77197123c7b847c46115b3e0dd2 432 SMART SM00897 80 285 9.5E-54 T 14-10-2018 IPR013702 FIST domain, N-terminal TSH58p_08845 2eb3c77197123c7b847c46115b3e0dd2 432 Pfam PF10442 FIST C domain 289 415 1.6E-15 T 14-10-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 TSH58p_16895 5da537fe43ef9af59287b76219455deb 439 Gene3D G3DSA:2.160.20.80 377 435 7.9E-14 T 14-10-2018 TSH58p_16895 5da537fe43ef9af59287b76219455deb 439 SUPERFAMILY SSF141571 40 124 2.88E-23 T 14-10-2018 TSH58p_16895 5da537fe43ef9af59287b76219455deb 439 Pfam PF00805 Pentapeptide repeats (8 copies) 288 325 2.7E-10 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_16895 5da537fe43ef9af59287b76219455deb 439 Pfam PF00805 Pentapeptide repeats (8 copies) 175 213 3.3E-12 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_16895 5da537fe43ef9af59287b76219455deb 439 Pfam PF00805 Pentapeptide repeats (8 copies) 214 251 3.2E-9 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_16895 5da537fe43ef9af59287b76219455deb 439 Pfam PF00805 Pentapeptide repeats (8 copies) 384 423 4.0E-12 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_16895 5da537fe43ef9af59287b76219455deb 439 Pfam PF00805 Pentapeptide repeats (8 copies) 328 365 4.3E-12 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_16895 5da537fe43ef9af59287b76219455deb 439 Pfam PF00805 Pentapeptide repeats (8 copies) 90 124 4.3E-9 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_16895 5da537fe43ef9af59287b76219455deb 439 Pfam PF00805 Pentapeptide repeats (8 copies) 45 84 4.3E-10 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_16895 5da537fe43ef9af59287b76219455deb 439 SUPERFAMILY SSF141571 287 433 3.22E-35 T 14-10-2018 TSH58p_16895 5da537fe43ef9af59287b76219455deb 439 SUPERFAMILY SSF141571 175 279 4.97E-23 T 14-10-2018 TSH58p_16895 5da537fe43ef9af59287b76219455deb 439 Gene3D G3DSA:2.160.20.80 146 258 6.8E-23 T 14-10-2018 TSH58p_16895 5da537fe43ef9af59287b76219455deb 439 Gene3D G3DSA:2.160.20.80 260 371 1.5E-28 T 14-10-2018 TSH58p_16895 5da537fe43ef9af59287b76219455deb 439 Gene3D G3DSA:2.160.20.80 28 130 4.9E-25 T 14-10-2018 TSH58p_20435 247f62650e328ce34426f879ae3432e1 273 SMART SM00052 12 258 2.6E-102 T 14-10-2018 IPR001633 EAL domain TSH58p_20435 247f62650e328ce34426f879ae3432e1 273 Gene3D G3DSA:3.20.20.450 15 269 1.4E-93 T 14-10-2018 IPR035919 EAL domain superfamily TSH58p_20435 247f62650e328ce34426f879ae3432e1 273 Pfam PF00563 EAL domain 19 253 5.9E-75 T 14-10-2018 IPR001633 EAL domain TSH58p_20435 247f62650e328ce34426f879ae3432e1 273 SUPERFAMILY SSF141868 18 265 9.55E-86 T 14-10-2018 IPR035919 EAL domain superfamily TSH58p_10260 59f59dc132692d148797bbe9e2cfa7ff 75 Pfam PF06667 Phage shock protein B 3 73 3.6E-29 T 14-10-2018 IPR009554 Phage shock protein B GO:0006355|GO:0009271 TSH58p_10260 59f59dc132692d148797bbe9e2cfa7ff 75 TIGRFAM TIGR02976 phageshock_pspB: phage shock protein B 1 74 1.5E-24 T 14-10-2018 IPR009554 Phage shock protein B GO:0006355|GO:0009271 TSH58p_10515 ecac4a34c5ef3827a584082249ceae85 212 Pfam PF00174 Oxidoreductase molybdopterin binding domain 49 193 1.6E-38 T 14-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 TSH58p_10515 ecac4a34c5ef3827a584082249ceae85 212 SUPERFAMILY SSF56524 8 211 3.4E-64 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 TSH58p_10515 ecac4a34c5ef3827a584082249ceae85 212 Gene3D G3DSA:3.90.420.10 43 211 6.5E-50 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 TSH58p_10405 ce73537215011f066ba92cdbb29f42c6 416 Pfam PF01494 FAD binding domain 14 326 1.8E-33 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 TSH58p_10405 ce73537215011f066ba92cdbb29f42c6 416 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 168 183 7.2E-22 T 14-10-2018 TSH58p_10405 ce73537215011f066ba92cdbb29f42c6 416 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 307 7.2E-22 T 14-10-2018 TSH58p_10405 ce73537215011f066ba92cdbb29f42c6 416 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 307 323 7.2E-22 T 14-10-2018 TSH58p_10405 ce73537215011f066ba92cdbb29f42c6 416 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 15 37 7.2E-22 T 14-10-2018 TSH58p_10405 ce73537215011f066ba92cdbb29f42c6 416 SUPERFAMILY SSF51905 14 398 4.15E-62 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_10405 ce73537215011f066ba92cdbb29f42c6 416 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 306 319 - T 14-10-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 TSH58p_10405 ce73537215011f066ba92cdbb29f42c6 416 Gene3D G3DSA:3.30.9.50 88 281 6.3E-99 T 14-10-2018 TSH58p_10405 ce73537215011f066ba92cdbb29f42c6 416 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 15 402 2.1E-130 T 14-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 TSH58p_10405 ce73537215011f066ba92cdbb29f42c6 416 Gene3D G3DSA:3.50.50.60 15 350 6.3E-99 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_23775 a3c9922c31219606b7f17a45c3420b77 127 Pfam PF01527 Transposase 17 70 2.4E-16 T 14-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 TSH58p_23775 a3c9922c31219606b7f17a45c3420b77 127 SUPERFAMILY SSF48295 16 63 1.73E-9 T 14-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 TSH58p_24000 4b47c99e57c881afd43f5545806c6b4e 653 Pfam PF13193 AMP-binding enzyme C-terminal domain 543 615 4.5E-9 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSH58p_24000 4b47c99e57c881afd43f5545806c6b4e 653 Gene3D G3DSA:3.40.50.12780 79 523 2.0E-55 T 14-10-2018 TSH58p_24000 4b47c99e57c881afd43f5545806c6b4e 653 Gene3D G3DSA:3.30.300.30 526 649 5.9E-17 T 14-10-2018 TSH58p_24000 4b47c99e57c881afd43f5545806c6b4e 653 ProSitePatterns PS00455 Putative AMP-binding domain signature. 271 282 - T 14-10-2018 IPR020845 AMP-binding, conserved site TSH58p_24000 4b47c99e57c881afd43f5545806c6b4e 653 SUPERFAMILY SSF56801 39 627 8.11E-125 T 14-10-2018 TSH58p_24000 4b47c99e57c881afd43f5545806c6b4e 653 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 8 651 9.8E-291 T 14-10-2018 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 TSH58p_24000 4b47c99e57c881afd43f5545806c6b4e 653 Pfam PF00501 AMP-binding enzyme 99 527 1.8E-42 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_23685 1711b2839473aaeacc56a01ef4a7ae9d 537 Pfam PF05199 GMC oxidoreductase 394 527 9.4E-36 T 14-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 TSH58p_23685 1711b2839473aaeacc56a01ef4a7ae9d 537 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 284 298 - T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 TSH58p_23685 1711b2839473aaeacc56a01ef4a7ae9d 537 PIRSF PIRSF000137 376 537 6.2E-44 T 14-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 TSH58p_23685 1711b2839473aaeacc56a01ef4a7ae9d 537 PIRSF PIRSF000137 13 373 1.2E-103 T 14-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 TSH58p_23685 1711b2839473aaeacc56a01ef4a7ae9d 537 Pfam PF00732 GMC oxidoreductase 31 325 3.2E-70 T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 TSH58p_23685 1711b2839473aaeacc56a01ef4a7ae9d 537 Gene3D G3DSA:1.10.1220.110 122 177 1.2E-169 T 14-10-2018 TSH58p_23685 1711b2839473aaeacc56a01ef4a7ae9d 537 SUPERFAMILY SSF51905 29 535 7.29E-79 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_23685 1711b2839473aaeacc56a01ef4a7ae9d 537 Gene3D G3DSA:3.50.50.60 31 530 1.2E-169 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_23685 1711b2839473aaeacc56a01ef4a7ae9d 537 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 107 130 - T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 TSH58p_23685 1711b2839473aaeacc56a01ef4a7ae9d 537 Gene3D G3DSA:4.10.450.10 64 226 1.2E-169 T 14-10-2018 IPR027424 Glucose Oxidase, domain 2 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 TSH58p_23685 1711b2839473aaeacc56a01ef4a7ae9d 537 SUPERFAMILY SSF54373 321 477 3.53E-36 T 14-10-2018 TSH58p_23685 1711b2839473aaeacc56a01ef4a7ae9d 537 Gene3D G3DSA:3.30.410.40 178 474 1.2E-169 T 14-10-2018 TSH58p_30245 b77c1dd33afce47a4fc6b2349b064648 151 Pfam PF01814 Hemerythrin HHE cation binding domain 8 137 3.4E-11 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 TSH58p_30245 b77c1dd33afce47a4fc6b2349b064648 151 Gene3D G3DSA:1.20.120.520 3 150 1.1E-8 T 14-10-2018 TSH58p_06175 2ca3fe496bff41194832657b5fcff512 339 Pfam PF00849 RNA pseudouridylate synthase 110 261 1.7E-36 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSH58p_06175 2ca3fe496bff41194832657b5fcff512 339 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 150 164 - T 14-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSH58p_06175 2ca3fe496bff41194832657b5fcff512 339 SUPERFAMILY SSF55120 97 328 1.2E-60 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSH58p_06175 2ca3fe496bff41194832657b5fcff512 339 Gene3D G3DSA:3.30.2350.10 102 325 2.7E-63 T 14-10-2018 TSH58p_06175 2ca3fe496bff41194832657b5fcff512 339 SUPERFAMILY SSF55174 21 70 3.3E-6 T 14-10-2018 TSH58p_06175 2ca3fe496bff41194832657b5fcff512 339 Gene3D G3DSA:3.10.290.10 9 73 2.7E-13 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TSH58p_06175 2ca3fe496bff41194832657b5fcff512 339 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 18 324 3.9E-63 T 14-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSH58p_19085 d71816227e5e1e86c83b88d93d5ad8ff 427 PIRSF PIRSF006066 1 427 1.4E-136 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSH58p_19085 d71816227e5e1e86c83b88d93d5ad8ff 427 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 8 416 1.2E-99 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TSH58p_19085 d71816227e5e1e86c83b88d93d5ad8ff 427 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 422 3.6E-118 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSH58p_16840 ae6f6bfffb427e3cbd4c8593e6d8e6e2 676 Pfam PF00512 His Kinase A (phospho-acceptor) domain 437 503 5.3E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_16840 ae6f6bfffb427e3cbd4c8593e6d8e6e2 676 Gene3D G3DSA:3.30.450.20 283 441 3.9E-29 T 14-10-2018 TSH58p_16840 ae6f6bfffb427e3cbd4c8593e6d8e6e2 676 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 296 419 3.6E-27 T 14-10-2018 IPR000014 PAS domain TSH58p_16840 ae6f6bfffb427e3cbd4c8593e6d8e6e2 676 SUPERFAMILY SSF55785 283 412 6.6E-29 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_16840 ae6f6bfffb427e3cbd4c8593e6d8e6e2 676 SMART SM00091 298 365 5.6E-10 T 14-10-2018 IPR000014 PAS domain TSH58p_16840 ae6f6bfffb427e3cbd4c8593e6d8e6e2 676 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 549 656 2.9E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_16840 ae6f6bfffb427e3cbd4c8593e6d8e6e2 676 SMART SM00387 548 658 1.7E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_16840 ae6f6bfffb427e3cbd4c8593e6d8e6e2 676 SMART SM00086 372 414 8.2E-7 T 14-10-2018 IPR001610 PAC motif TSH58p_16840 ae6f6bfffb427e3cbd4c8593e6d8e6e2 676 SUPERFAMILY SSF55874 497 659 4.06E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_16840 ae6f6bfffb427e3cbd4c8593e6d8e6e2 676 Gene3D G3DSA:1.10.287.130 442 503 2.3E-20 T 14-10-2018 TSH58p_16840 ae6f6bfffb427e3cbd4c8593e6d8e6e2 676 PRINTS PR00344 Bacterial sensor protein C-terminal signature 618 636 7.8E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_16840 ae6f6bfffb427e3cbd4c8593e6d8e6e2 676 PRINTS PR00344 Bacterial sensor protein C-terminal signature 642 655 7.8E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_16840 ae6f6bfffb427e3cbd4c8593e6d8e6e2 676 PRINTS PR00344 Bacterial sensor protein C-terminal signature 607 617 7.8E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_16840 ae6f6bfffb427e3cbd4c8593e6d8e6e2 676 PRINTS PR00344 Bacterial sensor protein C-terminal signature 589 603 7.8E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_16840 ae6f6bfffb427e3cbd4c8593e6d8e6e2 676 Pfam PF00989 PAS fold 299 411 6.9E-18 T 14-10-2018 IPR013767 PAS fold GO:0006355 TSH58p_16840 ae6f6bfffb427e3cbd4c8593e6d8e6e2 676 SUPERFAMILY SSF47384 424 504 5.49E-10 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_16840 ae6f6bfffb427e3cbd4c8593e6d8e6e2 676 Gene3D G3DSA:3.30.565.10 507 662 1.4E-40 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_16840 ae6f6bfffb427e3cbd4c8593e6d8e6e2 676 SMART SM00388 436 506 4.5E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_18310 d1c6f3716a76e0a61a1db380ba3b380b 263 Pfam PF13578 Methyltransferase domain 64 175 2.7E-10 T 14-10-2018 TSH58p_18310 d1c6f3716a76e0a61a1db380ba3b380b 263 SUPERFAMILY SSF53335 62 189 1.25E-7 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_18310 d1c6f3716a76e0a61a1db380ba3b380b 263 Gene3D G3DSA:3.40.50.150 59 203 1.3E-9 T 14-10-2018 TSH58p_12880 aa1b960453b016fe40f96e651a423395 339 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 34 331 1.4E-99 T 14-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 TSH58p_12880 aa1b960453b016fe40f96e651a423395 339 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 30 331 53.811 T 14-10-2018 IPR023009 Tyrosine recombinase XerC/XerD TSH58p_12880 aa1b960453b016fe40f96e651a423395 339 Gene3D G3DSA:1.10.150.130 29 126 9.6E-21 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal TSH58p_12880 aa1b960453b016fe40f96e651a423395 339 Gene3D G3DSA:1.10.443.10 138 325 1.6E-55 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TSH58p_12880 aa1b960453b016fe40f96e651a423395 339 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 28 331 55.193 T 14-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 TSH58p_12880 aa1b960453b016fe40f96e651a423395 339 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 32 117 2.6E-19 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 TSH58p_12880 aa1b960453b016fe40f96e651a423395 339 SUPERFAMILY SSF56349 33 324 5.89E-54 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TSH58p_12880 aa1b960453b016fe40f96e651a423395 339 Pfam PF00589 Phage integrase family 139 315 7.7E-41 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TSH58p_30260 52e98cd1444310992431a9bd68e4a1d3 264 Gene3D G3DSA:3.40.50.300 3 259 2.1E-67 T 14-10-2018 TSH58p_30260 52e98cd1444310992431a9bd68e4a1d3 264 SMART SM00382 35 224 7.5E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_30260 52e98cd1444310992431a9bd68e4a1d3 264 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_30260 52e98cd1444310992431a9bd68e4a1d3 264 SUPERFAMILY SSF52540 12 237 1.22E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_30260 52e98cd1444310992431a9bd68e4a1d3 264 Pfam PF00005 ABC transporter 26 175 6.4E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_27290 c68cb7027ee6f56aa2b90196a6a15111 337 Pfam PF09898 Uncharacterized protein conserved in bacteria (DUF2125) 25 333 1.1E-66 T 14-10-2018 IPR018666 Protein of unknown function DUF2125 TSH58p_13255 8db59c30739a0caa52a7f8d1e1b5fbc8 181 Gene3D G3DSA:1.10.10.10 1 101 7.7E-38 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_13255 8db59c30739a0caa52a7f8d1e1b5fbc8 181 Pfam PF14557 Putative AphA-like transcriptional regulator 2 177 1.4E-78 T 14-10-2018 IPR029434 Putative transcriptional regulator TSH58p_13255 8db59c30739a0caa52a7f8d1e1b5fbc8 181 Gene3D G3DSA:1.20.1280.20 104 181 5.0E-26 T 14-10-2018 IPR036386 HscB, C-terminal domain superfamily GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 TSH58p_13255 8db59c30739a0caa52a7f8d1e1b5fbc8 181 SUPERFAMILY SSF46785 13 180 1.94E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_21040 958501f2864c56a8fed5bd2a6fdf75b3 323 PIRSF PIRSF000535 8 317 1.7E-80 T 14-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 TSH58p_21040 958501f2864c56a8fed5bd2a6fdf75b3 323 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 11 314 4.7E-95 T 14-10-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 TSH58p_21040 958501f2864c56a8fed5bd2a6fdf75b3 323 Gene3D G3DSA:3.40.1190.20 9 318 2.9E-95 T 14-10-2018 IPR029056 Ribokinase-like TSH58p_21040 958501f2864c56a8fed5bd2a6fdf75b3 323 Pfam PF00294 pfkB family carbohydrate kinase 19 303 6.3E-52 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB TSH58p_21040 958501f2864c56a8fed5bd2a6fdf75b3 323 SUPERFAMILY SSF53613 12 305 1.56E-64 T 14-10-2018 IPR029056 Ribokinase-like TSH58p_21040 958501f2864c56a8fed5bd2a6fdf75b3 323 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 11 314 5.5E-97 T 14-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 TSH58p_21040 958501f2864c56a8fed5bd2a6fdf75b3 323 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 256 269 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TSH58p_31215 f1b9f8000fcc57e21289b3e6d2db892b 108 Pfam PF00034 Cytochrome c 25 106 2.2E-5 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_31215 f1b9f8000fcc57e21289b3e6d2db892b 108 SUPERFAMILY SSF46626 5 106 3.11E-15 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_31215 f1b9f8000fcc57e21289b3e6d2db892b 108 Gene3D G3DSA:1.10.760.10 2 108 2.4E-15 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_12990 2b285b4111a1022ef2b8f6cde05c5fb0 200 SUPERFAMILY SSF47240 35 88 9.74E-8 T 14-10-2018 IPR009078 Ferritin-like superfamily TSH58p_12990 2b285b4111a1022ef2b8f6cde05c5fb0 200 Pfam PF03232 Ubiquinone biosynthesis protein COQ7 38 198 4.6E-28 T 14-10-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 TSH58p_00580 1779e5899b6749ce701474727141521a 163 Pfam PF11154 Protein of unknown function (DUF2934) 4 40 1.3E-15 T 14-10-2018 IPR021327 Protein of unknown function DUF2934 TSH58p_20660 e5230e356bce4622bd57fe46ca9408d9 255 SUPERFAMILY SSF51182 24 184 1.6E-11 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_20660 e5230e356bce4622bd57fe46ca9408d9 255 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 209 250 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 TSH58p_20660 e5230e356bce4622bd57fe46ca9408d9 255 SUPERFAMILY SSF46689 209 253 1.25E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_20660 e5230e356bce4622bd57fe46ca9408d9 255 Gene3D G3DSA:1.10.10.60 157 255 4.2E-21 T 14-10-2018 TSH58p_20660 e5230e356bce4622bd57fe46ca9408d9 255 Pfam PF12833 Helix-turn-helix domain 178 253 3.1E-23 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TSH58p_20660 e5230e356bce4622bd57fe46ca9408d9 255 SMART SM00342 172 254 4.7E-24 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TSH58p_20660 e5230e356bce4622bd57fe46ca9408d9 255 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 223 238 1.8E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TSH58p_20660 e5230e356bce4622bd57fe46ca9408d9 255 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 238 254 1.8E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TSH58p_24045 0bb43bcc3f28d214279607b29933ebac 213 SUPERFAMILY SSF63965 6 210 1.31E-74 T 14-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 TSH58p_24045 0bb43bcc3f28d214279607b29933ebac 213 Gene3D G3DSA:3.40.50.10230 2 211 3.8E-83 T 14-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 TSH58p_24045 0bb43bcc3f28d214279607b29933ebac 213 Pfam PF02570 Precorrin-8X methylmutase 16 209 1.7E-72 T 14-10-2018 IPR003722 Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC GO:0009236|GO:0016993 TSH58p_27135 d0c00afd4b219a17f8254e14b267b42b 338 PIRSF PIRSF010376 2 305 1.6E-71 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 TSH58p_27135 d0c00afd4b219a17f8254e14b267b42b 338 SUPERFAMILY SSF55060 178 295 2.06E-23 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TSH58p_27135 d0c00afd4b219a17f8254e14b267b42b 338 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 4 299 30.229 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 TSH58p_27135 d0c00afd4b219a17f8254e14b267b42b 338 Gene3D G3DSA:3.30.230.10 1 175 1.0E-46 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSH58p_27135 d0c00afd4b219a17f8254e14b267b42b 338 Gene3D G3DSA:3.30.70.890 178 301 1.3E-25 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TSH58p_27135 d0c00afd4b219a17f8254e14b267b42b 338 Pfam PF00288 GHMP kinases N terminal domain 104 160 7.9E-9 T 14-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TSH58p_27135 d0c00afd4b219a17f8254e14b267b42b 338 Pfam PF08544 GHMP kinases C terminal 217 288 8.5E-9 T 14-10-2018 IPR013750 GHMP kinase, C-terminal domain TSH58p_27135 d0c00afd4b219a17f8254e14b267b42b 338 SUPERFAMILY SSF54211 7 172 6.15E-32 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSH58p_05980 2805a07921d0bd531e8f5a9ec7153c54 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 14-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 TSH58p_05980 2805a07921d0bd531e8f5a9ec7153c54 112 PIRSF PIRSF039144 1 112 9.3E-56 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TSH58p_05980 2805a07921d0bd531e8f5a9ec7153c54 112 SMART SM00938 4 105 1.3E-67 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TSH58p_05980 2805a07921d0bd531e8f5a9ec7153c54 112 PRINTS PR00340 P-II protein signature 83 103 1.7E-45 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TSH58p_05980 2805a07921d0bd531e8f5a9ec7153c54 112 PRINTS PR00340 P-II protein signature 2 17 1.7E-45 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TSH58p_05980 2805a07921d0bd531e8f5a9ec7153c54 112 PRINTS PR00340 P-II protein signature 23 41 1.7E-45 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TSH58p_05980 2805a07921d0bd531e8f5a9ec7153c54 112 PRINTS PR00340 P-II protein signature 52 75 1.7E-45 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TSH58p_05980 2805a07921d0bd531e8f5a9ec7153c54 112 SUPERFAMILY SSF54913 1 112 1.11E-46 T 14-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TSH58p_05980 2805a07921d0bd531e8f5a9ec7153c54 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 14-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 TSH58p_05980 2805a07921d0bd531e8f5a9ec7153c54 112 Gene3D G3DSA:3.30.70.120 1 112 1.4E-48 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TSH58p_05980 2805a07921d0bd531e8f5a9ec7153c54 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 1.1E-43 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TSH58p_11105 d56cf0f9ce3057c502ccdc48384e6dda 219 SUPERFAMILY SSF54427 14 216 6.14E-53 T 14-10-2018 IPR032710 NTF2-like domain superfamily TSH58p_11105 d56cf0f9ce3057c502ccdc48384e6dda 219 PIRSF PIRSF031890 1 219 4.5E-76 T 14-10-2018 IPR016985 Uncharacterised conserved protein UCP031890, Tim44-related TSH58p_11105 d56cf0f9ce3057c502ccdc48384e6dda 219 Gene3D G3DSA:3.10.450.240 66 219 3.4E-43 T 14-10-2018 TSH58p_11105 d56cf0f9ce3057c502ccdc48384e6dda 219 ProDom PD111165 RP434 3 212 2.0E-10 T 14-10-2018 TSH58p_11105 d56cf0f9ce3057c502ccdc48384e6dda 219 SMART SM00978 71 217 1.5E-51 T 14-10-2018 IPR007379 Tim44-like domain TSH58p_11105 d56cf0f9ce3057c502ccdc48384e6dda 219 Pfam PF04280 Tim44-like domain 72 215 8.3E-49 T 14-10-2018 IPR007379 Tim44-like domain TSH58p_31420 837649a7ac76c54af9a86678336c2c31 227 SUPERFAMILY SSF48008 85 213 8.11E-22 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_31420 837649a7ac76c54af9a86678336c2c31 227 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 78 2.2E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_31420 837649a7ac76c54af9a86678336c2c31 227 Gene3D G3DSA:1.10.10.10 5 79 8.9E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_31420 837649a7ac76c54af9a86678336c2c31 227 Pfam PF07729 FCD domain 90 206 5.7E-24 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_31420 837649a7ac76c54af9a86678336c2c31 227 SUPERFAMILY SSF46785 13 82 3.03E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_31420 837649a7ac76c54af9a86678336c2c31 227 SMART SM00345 20 78 1.2E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_31420 837649a7ac76c54af9a86678336c2c31 227 Gene3D G3DSA:1.20.120.530 81 217 5.7E-24 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_31420 837649a7ac76c54af9a86678336c2c31 227 SMART SM00895 88 207 7.8E-15 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_31420 837649a7ac76c54af9a86678336c2c31 227 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 68 4.7E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_31420 837649a7ac76c54af9a86678336c2c31 227 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 52 4.7E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_00605 e5ecd0aa5264173e4b3653a05b37dc5d 213 Pfam PF13690 Chemotaxis phosphatase CheX 67 149 6.1E-8 T 14-10-2018 IPR028051 Chemotaxis phosphatase CheX-like domain TSH58p_00605 e5ecd0aa5264173e4b3653a05b37dc5d 213 SUPERFAMILY SSF103039 4 195 8.28E-44 T 14-10-2018 IPR028976 CheC-like superfamily TSH58p_00605 e5ecd0aa5264173e4b3653a05b37dc5d 213 Gene3D G3DSA:3.40.1550.10 2 195 1.3E-49 T 14-10-2018 IPR028976 CheC-like superfamily TSH58p_00605 e5ecd0aa5264173e4b3653a05b37dc5d 213 Pfam PF04509 CheC-like family 8 43 4.8E-7 T 14-10-2018 IPR007597 CheC-like protein GO:0016787 TSH58p_10630 888ce3774cf2ea9de50f8971a367136b 563 Gene3D G3DSA:1.20.1480.50 185 270 1.0E-11 T 14-10-2018 TSH58p_10630 888ce3774cf2ea9de50f8971a367136b 563 SMART SM00283 303 550 2.4E-49 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_10630 888ce3774cf2ea9de50f8971a367136b 563 Pfam PF00672 HAMP domain 216 262 1.4E-6 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_10630 888ce3774cf2ea9de50f8971a367136b 563 Gene3D G3DSA:3.30.450.20 36 184 1.6E-35 T 14-10-2018 TSH58p_10630 888ce3774cf2ea9de50f8971a367136b 563 SMART SM01049 35 129 4.0E-21 T 14-10-2018 IPR033480 Single Cache domain 2 TSH58p_10630 888ce3774cf2ea9de50f8971a367136b 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 430 459 2.5E-21 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_10630 888ce3774cf2ea9de50f8971a367136b 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 8 33 2.5E-21 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_10630 888ce3774cf2ea9de50f8971a367136b 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 478 507 2.5E-21 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_10630 888ce3774cf2ea9de50f8971a367136b 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 401 428 2.5E-21 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_10630 888ce3774cf2ea9de50f8971a367136b 563 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 383 527 5.5E-32 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_10630 888ce3774cf2ea9de50f8971a367136b 563 Pfam PF17200 Single Cache domain 2 40 190 6.9E-31 T 14-10-2018 IPR033480 Single Cache domain 2 TSH58p_10630 888ce3774cf2ea9de50f8971a367136b 563 SUPERFAMILY SSF58104 234 556 1.18E-61 T 14-10-2018 TSH58p_10630 888ce3774cf2ea9de50f8971a367136b 563 SMART SM00304 213 266 1.2E-5 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_10630 888ce3774cf2ea9de50f8971a367136b 563 Gene3D G3DSA:1.10.287.950 271 560 5.4E-52 T 14-10-2018 TSH58p_32540 f5861ca292a55423f1bb9624ae5fb96b 315 Gene3D G3DSA:3.40.50.720 10 298 9.9E-56 T 14-10-2018 TSH58p_32540 f5861ca292a55423f1bb9624ae5fb96b 315 Gene3D G3DSA:3.30.360.10 129 313 9.9E-56 T 14-10-2018 TSH58p_32540 f5861ca292a55423f1bb9624ae5fb96b 315 SUPERFAMILY SSF55347 126 259 2.62E-12 T 14-10-2018 TSH58p_32540 f5861ca292a55423f1bb9624ae5fb96b 315 SUPERFAMILY SSF51735 2 141 2.18E-40 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_32540 f5861ca292a55423f1bb9624ae5fb96b 315 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 121 4.6E-20 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 TSH58p_24050 ad9fc801dcb01c46e9ef7ade71a671d8 250 Gene3D G3DSA:3.30.950.10 146 246 2.2E-14 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 TSH58p_24050 ad9fc801dcb01c46e9ef7ade71a671d8 250 SUPERFAMILY SSF53790 9 245 4.58E-43 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 TSH58p_24050 ad9fc801dcb01c46e9ef7ade71a671d8 250 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 14 226 1.1E-41 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 TSH58p_24050 ad9fc801dcb01c46e9ef7ade71a671d8 250 Gene3D G3DSA:3.40.1010.10 12 144 7.4E-28 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 TSH58p_24050 ad9fc801dcb01c46e9ef7ade71a671d8 250 PIRSF PIRSF036427 11 250 8.8E-65 T 14-10-2018 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 TSH58p_24050 ad9fc801dcb01c46e9ef7ade71a671d8 250 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 13 244 1.3E-60 T 14-10-2018 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 TSH58p_29080 d57bbfadbb2595a6e078b11a8d110a89 130 SUPERFAMILY SSF47188 1 121 1.83E-29 T 14-10-2018 IPR035938 Hemerythrin-like superfamily TSH58p_29080 d57bbfadbb2595a6e078b11a8d110a89 130 Gene3D G3DSA:1.20.120.50 1 125 1.1E-32 T 14-10-2018 IPR035938 Hemerythrin-like superfamily TSH58p_29080 d57bbfadbb2595a6e078b11a8d110a89 130 ProSitePatterns PS00550 Hemerythrin family signature. 49 72 - T 14-10-2018 IPR016131 Haemerythrin, iron-binding site GO:0046872 TSH58p_29080 d57bbfadbb2595a6e078b11a8d110a89 130 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 2 121 4.7E-31 T 14-10-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 TSH58p_29080 d57bbfadbb2595a6e078b11a8d110a89 130 Pfam PF01814 Hemerythrin HHE cation binding domain 4 120 3.6E-10 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 TSH58p_10685 0eef85875bac0271070305c39fefb3cb 179 Pfam PF13466 STAS domain 34 113 3.5E-12 T 14-10-2018 IPR002645 STAS domain TSH58p_10685 0eef85875bac0271070305c39fefb3cb 179 Gene3D G3DSA:3.30.750.24 19 131 8.5E-20 T 14-10-2018 IPR036513 STAS domain superfamily TSH58p_10685 0eef85875bac0271070305c39fefb3cb 179 SUPERFAMILY SSF52091 23 127 3.34E-18 T 14-10-2018 IPR036513 STAS domain superfamily TSH58p_02385 205db04e43098d9d89a6774451cbfc9c 679 Gene3D G3DSA:1.10.1370.10 144 604 1.2E-226 T 14-10-2018 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 TSH58p_02385 205db04e43098d9d89a6774451cbfc9c 679 Gene3D G3DSA:1.10.1370.40 17 670 1.2E-226 T 14-10-2018 TSH58p_02385 205db04e43098d9d89a6774451cbfc9c 679 Pfam PF01432 Peptidase family M3 228 671 1.1E-115 T 14-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 TSH58p_02385 205db04e43098d9d89a6774451cbfc9c 679 SUPERFAMILY SSF55486 1 672 1.69E-181 T 14-10-2018 TSH58p_11345 e497b151cfaa33717166ff6bee61789e 360 SUPERFAMILY SSF52540 122 303 3.64E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_11345 e497b151cfaa33717166ff6bee61789e 360 Pfam PF02562 PhoH-like protein 123 326 5.4E-92 T 14-10-2018 IPR003714 PhoH-like protein GO:0005524 TSH58p_11345 e497b151cfaa33717166ff6bee61789e 360 Gene3D G3DSA:3.40.50.300 120 326 4.3E-73 T 14-10-2018 TSH58p_13615 7ec1731dc903b105f560bc953b4756ce 466 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 41 51 - T 14-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 TSH58p_13615 7ec1731dc903b105f560bc953b4756ce 466 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 347 455 1.6E-41 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TSH58p_13615 7ec1731dc903b105f560bc953b4756ce 466 SUPERFAMILY SSF51905 1 322 2.24E-65 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_13615 7ec1731dc903b105f560bc953b4756ce 466 Gene3D G3DSA:3.50.50.60 7 328 7.5E-121 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_13615 7ec1731dc903b105f560bc953b4756ce 466 PIRSF PIRSF000350 1 462 2.5E-85 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 TSH58p_13615 7ec1731dc903b105f560bc953b4756ce 466 Gene3D G3DSA:3.30.390.30 346 466 1.5E-47 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TSH58p_13615 7ec1731dc903b105f560bc953b4756ce 466 SUPERFAMILY SSF55424 344 465 5.84E-44 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TSH58p_13615 7ec1731dc903b105f560bc953b4756ce 466 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 328 2.2E-73 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSH58p_13615 7ec1731dc903b105f560bc953b4756ce 466 Gene3D G3DSA:3.50.50.60 148 271 7.5E-121 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_13615 7ec1731dc903b105f560bc953b4756ce 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 136 154 8.0E-40 T 14-10-2018 TSH58p_13615 7ec1731dc903b105f560bc953b4756ce 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 175 193 8.0E-40 T 14-10-2018 TSH58p_13615 7ec1731dc903b105f560bc953b4756ce 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 8.0E-40 T 14-10-2018 TSH58p_13615 7ec1731dc903b105f560bc953b4756ce 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 315 8.0E-40 T 14-10-2018 TSH58p_13615 7ec1731dc903b105f560bc953b4756ce 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 280 8.0E-40 T 14-10-2018 TSH58p_13615 7ec1731dc903b105f560bc953b4756ce 466 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 6 466 1.2E-175 T 14-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 TSH58p_13615 7ec1731dc903b105f560bc953b4756ce 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 343 364 4.0E-79 T 14-10-2018 TSH58p_13615 7ec1731dc903b105f560bc953b4756ce 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 408 423 4.0E-79 T 14-10-2018 TSH58p_13615 7ec1731dc903b105f560bc953b4756ce 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 175 200 4.0E-79 T 14-10-2018 TSH58p_13615 7ec1731dc903b105f560bc953b4756ce 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 308 315 4.0E-79 T 14-10-2018 TSH58p_13615 7ec1731dc903b105f560bc953b4756ce 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 139 148 4.0E-79 T 14-10-2018 TSH58p_13615 7ec1731dc903b105f560bc953b4756ce 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 279 4.0E-79 T 14-10-2018 TSH58p_13615 7ec1731dc903b105f560bc953b4756ce 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 430 450 4.0E-79 T 14-10-2018 TSH58p_13615 7ec1731dc903b105f560bc953b4756ce 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 40 55 4.0E-79 T 14-10-2018 TSH58p_13615 7ec1731dc903b105f560bc953b4756ce 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 4.0E-79 T 14-10-2018 TSH58p_25110 aff0a1c468803ec23f46e8044cf0a5bd 636 Gene3D G3DSA:1.25.40.10 12 119 1.4E-23 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25110 aff0a1c468803ec23f46e8044cf0a5bd 636 Pfam PF13432 Tetratricopeptide repeat 150 203 2.8E-4 T 14-10-2018 TSH58p_25110 aff0a1c468803ec23f46e8044cf0a5bd 636 Pfam PF13432 Tetratricopeptide repeat 84 143 5.7E-6 T 14-10-2018 TSH58p_25110 aff0a1c468803ec23f46e8044cf0a5bd 636 Pfam PF13432 Tetratricopeptide repeat 13 77 1.9E-7 T 14-10-2018 TSH58p_25110 aff0a1c468803ec23f46e8044cf0a5bd 636 Gene3D G3DSA:3.40.50.11380 259 610 2.6E-129 T 14-10-2018 TSH58p_25110 aff0a1c468803ec23f46e8044cf0a5bd 636 SUPERFAMILY SSF48452 20 220 3.67E-39 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25110 aff0a1c468803ec23f46e8044cf0a5bd 636 SUPERFAMILY SSF53756 331 600 2.62E-5 T 14-10-2018 TSH58p_25110 aff0a1c468803ec23f46e8044cf0a5bd 636 Gene3D G3DSA:1.25.40.10 120 150 7.4E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25110 aff0a1c468803ec23f46e8044cf0a5bd 636 Pfam PF13844 Glycosyl transferase family 41 266 413 2.8E-29 T 14-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 TSH58p_25110 aff0a1c468803ec23f46e8044cf0a5bd 636 Pfam PF13844 Glycosyl transferase family 41 431 621 9.8E-25 T 14-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 TSH58p_25110 aff0a1c468803ec23f46e8044cf0a5bd 636 Gene3D G3DSA:1.25.40.10 151 186 3.8E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25110 aff0a1c468803ec23f46e8044cf0a5bd 636 Gene3D G3DSA:1.25.40.10 187 245 8.0E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25110 aff0a1c468803ec23f46e8044cf0a5bd 636 SMART SM00028 111 144 4.0E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25110 aff0a1c468803ec23f46e8044cf0a5bd 636 SMART SM00028 43 76 0.0018 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25110 aff0a1c468803ec23f46e8044cf0a5bd 636 SMART SM00028 179 212 42.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25110 aff0a1c468803ec23f46e8044cf0a5bd 636 SMART SM00028 9 42 370.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25110 aff0a1c468803ec23f46e8044cf0a5bd 636 SMART SM00028 145 178 0.0057 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25110 aff0a1c468803ec23f46e8044cf0a5bd 636 SMART SM00028 77 110 22.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25110 aff0a1c468803ec23f46e8044cf0a5bd 636 Gene3D G3DSA:3.40.50.2000 422 603 2.6E-129 T 14-10-2018 TSH58p_14415 d6d7d6f9af5e9ebbf693baffee19b63b 293 SUPERFAMILY SSF51735 10 169 8.72E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_14415 d6d7d6f9af5e9ebbf693baffee19b63b 293 Gene3D G3DSA:1.10.1040.10 168 293 9.4E-40 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSH58p_14415 d6d7d6f9af5e9ebbf693baffee19b63b 293 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 13 26 - T 14-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 TSH58p_14415 d6d7d6f9af5e9ebbf693baffee19b63b 293 Gene3D G3DSA:3.40.50.720 1 167 1.1E-50 T 14-10-2018 TSH58p_14415 d6d7d6f9af5e9ebbf693baffee19b63b 293 PIRSF PIRSF000103 3 293 1.6E-69 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 TSH58p_14415 d6d7d6f9af5e9ebbf693baffee19b63b 293 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 171 288 4.6E-35 T 14-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 TSH58p_14415 d6d7d6f9af5e9ebbf693baffee19b63b 293 SUPERFAMILY SSF48179 169 291 3.17E-41 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_14415 d6d7d6f9af5e9ebbf693baffee19b63b 293 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 11 168 1.3E-45 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 TSH58p_27955 9af2c2d7a952c2d53337f5c9bb00e953 364 Gene3D G3DSA:3.90.79.10 239 363 1.1E-13 T 14-10-2018 TSH58p_27955 9af2c2d7a952c2d53337f5c9bb00e953 364 SMART SM00525 206 226 3.2E-4 T 14-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 TSH58p_27955 9af2c2d7a952c2d53337f5c9bb00e953 364 ProSitePatterns PS01155 Endonuclease III family signature. 119 146 - T 14-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 TSH58p_27955 9af2c2d7a952c2d53337f5c9bb00e953 364 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 22 279 2.7E-92 T 14-10-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 TSH58p_27955 9af2c2d7a952c2d53337f5c9bb00e953 364 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 207 223 - T 14-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 TSH58p_27955 9af2c2d7a952c2d53337f5c9bb00e953 364 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 53 170 3.3E-16 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TSH58p_27955 9af2c2d7a952c2d53337f5c9bb00e953 364 SUPERFAMILY SSF55811 235 360 2.23E-22 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TSH58p_27955 9af2c2d7a952c2d53337f5c9bb00e953 364 SUPERFAMILY SSF48150 21 237 3.14E-70 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TSH58p_27955 9af2c2d7a952c2d53337f5c9bb00e953 364 Pfam PF14815 NUDIX domain 250 358 3.4E-22 T 14-10-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 TSH58p_27955 9af2c2d7a952c2d53337f5c9bb00e953 364 SMART SM00478 56 205 1.4E-41 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TSH58p_27955 9af2c2d7a952c2d53337f5c9bb00e953 364 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 207 223 1.2E-6 T 14-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 TSH58p_27955 9af2c2d7a952c2d53337f5c9bb00e953 364 Gene3D G3DSA:1.10.340.30 34 149 6.6E-83 T 14-10-2018 TSH58p_27955 9af2c2d7a952c2d53337f5c9bb00e953 364 Gene3D G3DSA:1.10.1670.10 23 227 6.6E-83 T 14-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 TSH58p_21295 a1a749d483daeba901760dcdd4c18d3f 328 Hamap MF_01601 ADP-L-glycero-D-manno-heptose-6-epimerase [hldD]. 1 323 47.058 T 14-10-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 TSH58p_21295 a1a749d483daeba901760dcdd4c18d3f 328 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 249 1.8E-38 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TSH58p_21295 a1a749d483daeba901760dcdd4c18d3f 328 Gene3D G3DSA:3.90.25.10 174 304 1.1E-112 T 14-10-2018 TSH58p_21295 a1a749d483daeba901760dcdd4c18d3f 328 Gene3D G3DSA:3.40.50.720 3 317 1.1E-112 T 14-10-2018 TSH58p_21295 a1a749d483daeba901760dcdd4c18d3f 328 TIGRFAM TIGR02197 heptose_epim: ADP-glyceromanno-heptose 6-epimerase 2 322 4.6E-116 T 14-10-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 TSH58p_21295 a1a749d483daeba901760dcdd4c18d3f 328 SUPERFAMILY SSF51735 2 325 1.06E-58 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_10140 f1ffced84e6404886fce4811e0048f9c 303 SUPERFAMILY SSF103481 47 138 2.22E-12 T 14-10-2018 TSH58p_10140 f1ffced84e6404886fce4811e0048f9c 303 Pfam PF00892 EamA-like transporter family 4 136 4.4E-15 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_10140 f1ffced84e6404886fce4811e0048f9c 303 Pfam PF00892 EamA-like transporter family 163 301 2.0E-16 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_10140 f1ffced84e6404886fce4811e0048f9c 303 SUPERFAMILY SSF103481 203 301 9.94E-10 T 14-10-2018 TSH58p_31490 7c734074cdfb6371a3e56686b295d462 392 Gene3D G3DSA:1.10.10.10 3 78 4.4E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_31490 7c734074cdfb6371a3e56686b295d462 392 Pfam PF00480 ROK family 94 381 5.6E-53 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TSH58p_31490 7c734074cdfb6371a3e56686b295d462 392 Gene3D G3DSA:3.30.420.40 92 375 1.8E-84 T 14-10-2018 TSH58p_31490 7c734074cdfb6371a3e56686b295d462 392 Pfam PF12802 MarR family 14 67 2.5E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_31490 7c734074cdfb6371a3e56686b295d462 392 Gene3D G3DSA:3.30.420.40 208 367 1.8E-84 T 14-10-2018 TSH58p_31490 7c734074cdfb6371a3e56686b295d462 392 SUPERFAMILY SSF46785 10 75 4.89E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_31490 7c734074cdfb6371a3e56686b295d462 392 SUPERFAMILY SSF53067 83 382 3.17E-53 T 14-10-2018 TSH58p_05790 3f7985c1e3132d1a162b37c3833bd7a2 285 Gene3D G3DSA:3.40.50.1820 50 284 4.2E-53 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_05790 3f7985c1e3132d1a162b37c3833bd7a2 285 SUPERFAMILY SSF53474 62 284 1.62E-39 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_05790 3f7985c1e3132d1a162b37c3833bd7a2 285 Pfam PF01738 Dienelactone hydrolase family 75 282 1.4E-48 T 14-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 TSH58p_15190 2bc954fe6a04997d2550fbc9dc2fafbf 131 Gene3D G3DSA:3.90.470.10 3 131 5.4E-37 T 14-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 TSH58p_15190 2bc954fe6a04997d2550fbc9dc2fafbf 131 SUPERFAMILY SSF54843 11 123 1.83E-35 T 14-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 TSH58p_15190 2bc954fe6a04997d2550fbc9dc2fafbf 131 ProSitePatterns PS00464 Ribosomal protein L22 signature. 95 119 - T 14-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15190 2bc954fe6a04997d2550fbc9dc2fafbf 131 Pfam PF00237 Ribosomal protein L22p/L17e 20 119 6.1E-28 T 14-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 TSH58p_15190 2bc954fe6a04997d2550fbc9dc2fafbf 131 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 20 119 7.5E-27 T 14-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_15190 2bc954fe6a04997d2550fbc9dc2fafbf 131 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 13 122 23.121 T 14-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_22065 68ae1a5aaad41e6450c67d1c459a6ce8 454 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 19 450 61.09 T 14-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 TSH58p_22065 68ae1a5aaad41e6450c67d1c459a6ce8 454 Gene3D G3DSA:3.40.50.12160 20 137 1.2E-28 T 14-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily TSH58p_22065 68ae1a5aaad41e6450c67d1c459a6ce8 454 Gene3D G3DSA:3.80.30.20 148 389 7.0E-71 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TSH58p_22065 68ae1a5aaad41e6450c67d1c459a6ce8 454 SUPERFAMILY SSF102114 134 381 7.85E-51 T 14-10-2018 TSH58p_22065 68ae1a5aaad41e6450c67d1c459a6ce8 454 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 154 174 - T 14-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 TSH58p_22065 68ae1a5aaad41e6450c67d1c459a6ce8 454 Pfam PF04055 Radical SAM superfamily 156 333 1.6E-27 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSH58p_22065 68ae1a5aaad41e6450c67d1c459a6ce8 454 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 20 448 1.6E-102 T 14-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 TSH58p_22065 68ae1a5aaad41e6450c67d1c459a6ce8 454 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 20 448 8.9E-177 T 14-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 TSH58p_22065 68ae1a5aaad41e6450c67d1c459a6ce8 454 Pfam PF00919 Uncharacterized protein family UPF0004 20 108 8.1E-20 T 14-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 TSH58p_22065 68ae1a5aaad41e6450c67d1c459a6ce8 454 Gene3D G3DSA:2.40.50.140 390 454 2.5E-22 T 14-10-2018 TSH58p_22065 68ae1a5aaad41e6450c67d1c459a6ce8 454 SMART SM00729 150 375 1.3E-48 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSH58p_14540 593ad8793c0246468a2e0e43e1527bf3 665 Gene3D G3DSA:3.20.20.80 129 540 5.1E-163 T 14-10-2018 TSH58p_14540 593ad8793c0246468a2e0e43e1527bf3 665 SMART SM00642 115 484 1.5E-12 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSH58p_14540 593ad8793c0246468a2e0e43e1527bf3 665 SUPERFAMILY SSF81296 31 119 1.86E-15 T 14-10-2018 IPR014756 Immunoglobulin E-set TSH58p_14540 593ad8793c0246468a2e0e43e1527bf3 665 Pfam PF11941 Domain of unknown function (DUF3459) 531 641 4.4E-19 T 14-10-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) TSH58p_14540 593ad8793c0246468a2e0e43e1527bf3 665 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 43 569 1.1E-184 T 14-10-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|MetaCyc: PWY-2661 TSH58p_14540 593ad8793c0246468a2e0e43e1527bf3 665 Gene3D G3DSA:1.10.10.760 470 514 5.1E-163 T 14-10-2018 TSH58p_14540 593ad8793c0246468a2e0e43e1527bf3 665 PIRSF PIRSF006337 28 586 5.7E-189 T 14-10-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|MetaCyc: PWY-2661 TSH58p_14540 593ad8793c0246468a2e0e43e1527bf3 665 Pfam PF00128 Alpha amylase, catalytic domain 157 235 2.0E-11 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSH58p_14540 593ad8793c0246468a2e0e43e1527bf3 665 SUPERFAMILY SSF51445 116 546 8.16E-105 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_14540 593ad8793c0246468a2e0e43e1527bf3 665 Gene3D G3DSA:2.60.40.10 29 125 1.2E-21 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_15295 5e2dae8e6c9ab07e143130ae99f4c7b1 436 PIRSF PIRSF001434 1 434 1.1E-123 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TSH58p_15295 5e2dae8e6c9ab07e143130ae99f4c7b1 436 Gene3D G3DSA:3.40.640.10 7 290 2.5E-98 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_15295 5e2dae8e6c9ab07e143130ae99f4c7b1 436 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 10 430 2.0E-131 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TSH58p_15295 5e2dae8e6c9ab07e143130ae99f4c7b1 436 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 8 430 8.2E-178 T 14-10-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 TSH58p_15295 5e2dae8e6c9ab07e143130ae99f4c7b1 436 Gene3D G3DSA:3.90.1150.10 294 436 1.2E-45 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_15295 5e2dae8e6c9ab07e143130ae99f4c7b1 436 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 202 216 - T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TSH58p_15295 5e2dae8e6c9ab07e143130ae99f4c7b1 436 SUPERFAMILY SSF53383 8 431 8.64E-121 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_27970 4d1a00359c24db51537711f0a95a07ab 141 Pfam PF02152 Dihydroneopterin aldolase 38 137 1.3E-21 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TSH58p_27970 4d1a00359c24db51537711f0a95a07ab 141 Gene3D G3DSA:3.30.1130.10 14 141 6.9E-34 T 14-10-2018 TSH58p_27970 4d1a00359c24db51537711f0a95a07ab 141 SMART SM00905 38 138 8.5E-25 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TSH58p_27970 4d1a00359c24db51537711f0a95a07ab 141 TIGRFAM TIGR00526 folB_dom: FolB domain 39 140 6.7E-15 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TSH58p_27970 4d1a00359c24db51537711f0a95a07ab 141 SUPERFAMILY SSF55620 39 140 5.23E-21 T 14-10-2018 TSH58p_25500 0adc27bbdc6cbe3bfca08d8d1a580985 418 Gene3D G3DSA:3.60.21.10 1 287 1.9E-74 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like TSH58p_25500 0adc27bbdc6cbe3bfca08d8d1a580985 418 Pfam PF00149 Calcineurin-like phosphoesterase 1 98 2.1E-11 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TSH58p_25500 0adc27bbdc6cbe3bfca08d8d1a580985 418 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 261 5.4E-54 T 14-10-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 TSH58p_25500 0adc27bbdc6cbe3bfca08d8d1a580985 418 SUPERFAMILY SSF56300 1 350 1.61E-48 T 14-10-2018 TSH58p_25500 0adc27bbdc6cbe3bfca08d8d1a580985 418 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 288 395 1.7E-11 T 14-10-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain TSH58p_13165 4f755681d06b0d96e3cc113aad45fc93 130 SUPERFAMILY SSF50104 1 119 8.12E-47 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily TSH58p_13165 4f755681d06b0d96e3cc113aad45fc93 130 ProSitePatterns PS01015 Ribosomal protein L19 signature. 90 105 - T 14-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_13165 4f755681d06b0d96e3cc113aad45fc93 130 PIRSF PIRSF002191 1 130 1.3E-55 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_13165 4f755681d06b0d96e3cc113aad45fc93 130 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 1 117 1.1E-49 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_13165 4f755681d06b0d96e3cc113aad45fc93 130 PRINTS PR00061 Ribosomal protein L19 signature 38 67 2.0E-37 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_13165 4f755681d06b0d96e3cc113aad45fc93 130 PRINTS PR00061 Ribosomal protein L19 signature 8 37 2.0E-37 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_13165 4f755681d06b0d96e3cc113aad45fc93 130 PRINTS PR00061 Ribosomal protein L19 signature 92 117 2.0E-37 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_13165 4f755681d06b0d96e3cc113aad45fc93 130 Gene3D G3DSA:2.30.30.790 2 119 2.7E-17 T 14-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_13165 4f755681d06b0d96e3cc113aad45fc93 130 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 118 31.911 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_13165 4f755681d06b0d96e3cc113aad45fc93 130 Pfam PF01245 Ribosomal protein L19 3 117 2.4E-49 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_12235 882a528dacb25bc7a8481827759d9db9 337 Pfam PF01636 Phosphotransferase enzyme family 23 260 1.8E-18 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase TSH58p_12235 882a528dacb25bc7a8481827759d9db9 337 SUPERFAMILY SSF56112 6 318 3.91E-35 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily TSH58p_12235 882a528dacb25bc7a8481827759d9db9 337 Gene3D G3DSA:3.90.1200.10 92 332 6.1E-58 T 14-10-2018 TSH58p_12235 882a528dacb25bc7a8481827759d9db9 337 Gene3D G3DSA:3.30.200.20 1 91 1.4E-24 T 14-10-2018 TSH58p_32280 24462821dafb22dd23a280177e6ff719 360 Pfam PF00356 Bacterial regulatory proteins, lacI family 22 66 2.2E-14 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TSH58p_32280 24462821dafb22dd23a280177e6ff719 360 Gene3D G3DSA:1.10.260.40 19 74 3.3E-17 T 14-10-2018 TSH58p_32280 24462821dafb22dd23a280177e6ff719 360 Gene3D G3DSA:3.40.50.2300 75 325 2.5E-50 T 14-10-2018 TSH58p_32280 24462821dafb22dd23a280177e6ff719 360 SUPERFAMILY SSF53822 78 343 1.05E-47 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_32280 24462821dafb22dd23a280177e6ff719 360 Gene3D G3DSA:3.40.50.2300 179 310 2.5E-50 T 14-10-2018 TSH58p_32280 24462821dafb22dd23a280177e6ff719 360 SUPERFAMILY SSF47413 20 78 1.13E-12 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_32280 24462821dafb22dd23a280177e6ff719 360 SMART SM00354 19 90 1.0E-20 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TSH58p_32280 24462821dafb22dd23a280177e6ff719 360 Pfam PF13377 Periplasmic binding protein-like domain 187 346 1.7E-21 T 14-10-2018 TSH58p_09030 f6ae95a65cf6e8ba98aac947b1faf919 679 SMART SM00889 459 576 2.1E-55 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TSH58p_09030 f6ae95a65cf6e8ba98aac947b1faf919 679 SUPERFAMILY SSF54980 384 461 4.32E-18 T 14-10-2018 IPR035647 EF-G domain III/V-like TSH58p_09030 f6ae95a65cf6e8ba98aac947b1faf919 679 Gene3D G3DSA:3.30.230.10 463 666 3.2E-66 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSH58p_09030 f6ae95a65cf6e8ba98aac947b1faf919 679 Gene3D G3DSA:3.30.70.870 384 462 4.3E-23 T 14-10-2018 TSH58p_09030 f6ae95a65cf6e8ba98aac947b1faf919 679 Gene3D G3DSA:2.40.30.10 291 377 3.9E-15 T 14-10-2018 TSH58p_09030 f6ae95a65cf6e8ba98aac947b1faf919 679 Gene3D G3DSA:3.30.70.240 582 655 3.2E-66 T 14-10-2018 TSH58p_09030 f6ae95a65cf6e8ba98aac947b1faf919 679 Pfam PF14492 Elongation Factor G, domain II 383 453 5.3E-23 T 14-10-2018 TSH58p_09030 f6ae95a65cf6e8ba98aac947b1faf919 679 SUPERFAMILY SSF50447 247 373 1.69E-16 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSH58p_09030 f6ae95a65cf6e8ba98aac947b1faf919 679 SUPERFAMILY SSF52540 6 277 9.71E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_09030 f6ae95a65cf6e8ba98aac947b1faf919 679 SMART SM00838 578 668 1.4E-13 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like TSH58p_09030 f6ae95a65cf6e8ba98aac947b1faf919 679 Pfam PF03764 Elongation factor G, domain IV 458 575 1.1E-37 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TSH58p_09030 f6ae95a65cf6e8ba98aac947b1faf919 679 Pfam PF00009 Elongation factor Tu GTP binding domain 12 273 2.4E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_09030 f6ae95a65cf6e8ba98aac947b1faf919 679 Pfam PF00679 Elongation factor G C-terminus 578 667 8.4E-19 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like TSH58p_09030 f6ae95a65cf6e8ba98aac947b1faf919 679 SUPERFAMILY SSF54980 581 669 3.93E-18 T 14-10-2018 IPR035647 EF-G domain III/V-like TSH58p_09030 f6ae95a65cf6e8ba98aac947b1faf919 679 Gene3D G3DSA:3.40.50.300 4 281 2.6E-49 T 14-10-2018 TSH58p_09030 f6ae95a65cf6e8ba98aac947b1faf919 679 SUPERFAMILY SSF54211 458 577 6.07E-36 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSH58p_19660 4d1a9be85420e1dfa3ec59f3dc2ed399 159 Pfam PF13404 AsnC-type helix-turn-helix domain 3 44 4.9E-19 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSH58p_19660 4d1a9be85420e1dfa3ec59f3dc2ed399 159 SUPERFAMILY SSF54909 64 145 1.61E-19 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel TSH58p_19660 4d1a9be85420e1dfa3ec59f3dc2ed399 159 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 14-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site TSH58p_19660 4d1a9be85420e1dfa3ec59f3dc2ed399 159 SUPERFAMILY SSF46785 3 93 9.57E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_19660 4d1a9be85420e1dfa3ec59f3dc2ed399 159 Gene3D G3DSA:1.10.10.10 3 55 3.1E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_19660 4d1a9be85420e1dfa3ec59f3dc2ed399 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 3.1E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSH58p_19660 4d1a9be85420e1dfa3ec59f3dc2ed399 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 3.1E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSH58p_19660 4d1a9be85420e1dfa3ec59f3dc2ed399 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 3.1E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSH58p_19660 4d1a9be85420e1dfa3ec59f3dc2ed399 159 SMART SM00344 3 112 3.1E-45 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TSH58p_19660 4d1a9be85420e1dfa3ec59f3dc2ed399 159 Gene3D G3DSA:3.30.70.920 56 139 1.7E-24 T 14-10-2018 TSH58p_19660 4d1a9be85420e1dfa3ec59f3dc2ed399 159 Pfam PF01037 Lrp/AsnC ligand binding domain 69 142 2.5E-20 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TSH58p_01465 620de7e6f3697d702d215321f510d6e6 645 Pfam PF12704 MacB-like periplasmic core domain 273 490 4.2E-33 T 14-10-2018 IPR025857 MacB-like periplasmic core domain TSH58p_01465 620de7e6f3697d702d215321f510d6e6 645 Gene3D G3DSA:3.40.50.300 4 249 1.6E-72 T 14-10-2018 TSH58p_01465 620de7e6f3697d702d215321f510d6e6 645 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_01465 620de7e6f3697d702d215321f510d6e6 645 Pfam PF00005 ABC transporter 26 174 1.3E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_01465 620de7e6f3697d702d215321f510d6e6 645 Pfam PF02687 FtsX-like permease family 552 638 1.7E-8 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 TSH58p_01465 620de7e6f3697d702d215321f510d6e6 645 SUPERFAMILY SSF52540 5 227 1.69E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_01465 620de7e6f3697d702d215321f510d6e6 645 SMART SM00382 35 222 9.8E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_06060 c0392c86435f630ac8b745bbc8c6a9ab 427 SUPERFAMILY SSF109854 11 133 1.1E-6 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TSH58p_06060 c0392c86435f630ac8b745bbc8c6a9ab 427 Gene3D G3DSA:3.90.1580.10 170 427 1.2E-40 T 14-10-2018 TSH58p_06060 c0392c86435f630ac8b745bbc8c6a9ab 427 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 11 424 1.6E-169 T 14-10-2018 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 TSH58p_06060 c0392c86435f630ac8b745bbc8c6a9ab 427 SUPERFAMILY SSF56436 179 426 1.11E-69 T 14-10-2018 IPR016187 C-type lectin fold TSH58p_06060 c0392c86435f630ac8b745bbc8c6a9ab 427 Pfam PF12867 DinB superfamily 15 129 5.0E-13 T 14-10-2018 IPR024775 DinB-like domain TSH58p_06060 c0392c86435f630ac8b745bbc8c6a9ab 427 Pfam PF03781 Sulfatase-modifying factor enzyme 1 179 424 1.0E-33 T 14-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 TSH58p_32510 f252e3c67ea32cf2d54948eeae1ec4c0 236 SMART SM00382 32 209 1.9E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_32510 f252e3c67ea32cf2d54948eeae1ec4c0 236 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_32510 f252e3c67ea32cf2d54948eeae1ec4c0 236 Gene3D G3DSA:3.40.50.300 3 233 4.6E-55 T 14-10-2018 TSH58p_32510 f252e3c67ea32cf2d54948eeae1ec4c0 236 Pfam PF00005 ABC transporter 24 163 8.5E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_32510 f252e3c67ea32cf2d54948eeae1ec4c0 236 SUPERFAMILY SSF52540 7 228 2.07E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_28520 d23c6b94f35199612cc0663c77b8b631 417 SUPERFAMILY SSF56059 109 317 8.31E-30 T 14-10-2018 TSH58p_28520 d23c6b94f35199612cc0663c77b8b631 417 Gene3D G3DSA:3.30.470.20 105 413 4.9E-54 T 14-10-2018 TSH58p_28520 d23c6b94f35199612cc0663c77b8b631 417 Pfam PF13535 ATP-grasp domain 147 295 1.5E-12 T 14-10-2018 TSH58p_00180 a3c59283a387a0a678ce40d035c9526b 417 Pfam PF07690 Major Facilitator Superfamily 205 388 4.0E-16 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_00180 a3c59283a387a0a678ce40d035c9526b 417 Gene3D G3DSA:1.20.1250.20 201 401 1.9E-18 T 14-10-2018 TSH58p_00180 a3c59283a387a0a678ce40d035c9526b 417 Gene3D G3DSA:1.20.1250.20 4 189 6.1E-10 T 14-10-2018 TSH58p_00180 a3c59283a387a0a678ce40d035c9526b 417 SUPERFAMILY SSF103473 6 380 4.05E-34 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_04765 7c41f1ad8471fc1fe036415cbfd5157a 229 SUPERFAMILY SSF55120 3 222 1.39E-60 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSH58p_04765 7c41f1ad8471fc1fe036415cbfd5157a 229 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 56 70 - T 14-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSH58p_04765 7c41f1ad8471fc1fe036415cbfd5157a 229 Pfam PF00849 RNA pseudouridylate synthase 18 165 1.9E-36 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSH58p_04765 7c41f1ad8471fc1fe036415cbfd5157a 229 Gene3D G3DSA:3.30.2350.10 1 210 3.9E-62 T 14-10-2018 TSH58p_29020 66163e2bb2a57deddd399f0386dfacdb 324 Pfam PF07859 alpha/beta hydrolase fold 93 298 8.3E-64 T 14-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 TSH58p_29020 66163e2bb2a57deddd399f0386dfacdb 324 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 93 109 - T 14-10-2018 IPR002168 Lipase, GDXG, putative histidine active site GO:0016787 Reactome: R-HSA-163560 TSH58p_29020 66163e2bb2a57deddd399f0386dfacdb 324 SUPERFAMILY SSF53474 56 307 2.21E-65 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_29020 66163e2bb2a57deddd399f0386dfacdb 324 Gene3D G3DSA:3.40.50.1820 5 324 1.3E-86 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_12760 baf5b3cf7f70bdb51df1f01c704c9cc6 129 Pfam PF06305 Lipopolysaccharide assembly protein A domain 23 86 6.7E-12 T 14-10-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 TSH58p_25430 8a68b636f7f068a0d690d32dfb11bd12 212 Pfam PF05433 Glycine zipper 2TM domain 9 51 2.8E-7 T 14-10-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 TSH58p_11080 92c45958c11ca70f8191ebe9c1ae7d64 142 Pfam PF03653 Uncharacterised protein family (UPF0093) 2 142 5.8E-61 T 14-10-2018 IPR005265 Uncharacterised protein family UPF0093 TSH58p_11080 92c45958c11ca70f8191ebe9c1ae7d64 142 TIGRFAM TIGR00701 TIGR00701: TIGR00701 family protein 3 142 3.0E-53 T 14-10-2018 IPR005265 Uncharacterised protein family UPF0093 TSH58p_11080 92c45958c11ca70f8191ebe9c1ae7d64 142 PIRSF PIRSF004638 1 142 4.4E-60 T 14-10-2018 IPR005265 Uncharacterised protein family UPF0093 TSH58p_00110 57664ae0ad1b1fe0b72cd8dd2f85ea26 208 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_00110 57664ae0ad1b1fe0b72cd8dd2f85ea26 208 SUPERFAMILY SSF46894 140 206 8.5E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_00110 57664ae0ad1b1fe0b72cd8dd2f85ea26 208 SMART SM00421 147 204 9.9E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_00110 57664ae0ad1b1fe0b72cd8dd2f85ea26 208 Gene3D G3DSA:3.40.50.2300 8 138 3.8E-44 T 14-10-2018 TSH58p_00110 57664ae0ad1b1fe0b72cd8dd2f85ea26 208 Pfam PF00072 Response regulator receiver domain 14 122 2.2E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_00110 57664ae0ad1b1fe0b72cd8dd2f85ea26 208 SUPERFAMILY SSF52172 11 160 6.97E-34 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_00110 57664ae0ad1b1fe0b72cd8dd2f85ea26 208 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 202 3.4E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_00110 57664ae0ad1b1fe0b72cd8dd2f85ea26 208 SMART SM00448 12 123 3.1E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_00110 57664ae0ad1b1fe0b72cd8dd2f85ea26 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 1.1E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_00110 57664ae0ad1b1fe0b72cd8dd2f85ea26 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 1.1E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_00110 57664ae0ad1b1fe0b72cd8dd2f85ea26 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 1.1E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_00110 57664ae0ad1b1fe0b72cd8dd2f85ea26 208 Gene3D G3DSA:1.10.10.10 141 207 2.2E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_16095 5878c8e57f13411c607f55813dbcf3c9 191 SUPERFAMILY SSF143456 10 191 1.07E-62 T 14-10-2018 TSH58p_16095 5878c8e57f13411c607f55813dbcf3c9 191 Gene3D G3DSA:3.40.1740.10 6 191 7.5E-68 T 14-10-2018 TSH58p_16095 5878c8e57f13411c607f55813dbcf3c9 191 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 9 191 36.09 T 14-10-2018 IPR003774 Protein of unknown function UPF0301 TSH58p_16095 5878c8e57f13411c607f55813dbcf3c9 191 Pfam PF02622 Uncharacterized ACR, COG1678 20 178 2.8E-46 T 14-10-2018 IPR003774 Protein of unknown function UPF0301 TSH58p_19200 232dac98a094ee47e91db140a8426967 446 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 349 358 - T 14-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSH58p_19200 232dac98a094ee47e91db140a8426967 446 Gene3D G3DSA:3.40.50.12240 13 440 1.6E-138 T 14-10-2018 TSH58p_19200 232dac98a094ee47e91db140a8426967 446 TIGRFAM TIGR03498 FliI_clade3: flagellar protein export ATPase FliI 21 437 2.8E-188 T 14-10-2018 IPR022426 Flagellum-specific ATP synthase FliI, clade 3 GO:0009288|GO:0016887|GO:0030257|GO:0044781 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSH58p_19200 232dac98a094ee47e91db140a8426967 446 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 147 358 1.4E-70 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSH58p_19200 232dac98a094ee47e91db140a8426967 446 SUPERFAMILY SSF52540 93 362 2.48E-92 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_19200 232dac98a094ee47e91db140a8426967 446 SMART SM00382 159 343 2.8E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_19200 232dac98a094ee47e91db140a8426967 446 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 5 438 3.2E-153 T 14-10-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSH58p_25665 7f9d3793d601bccab85970e074734b93 418 Gene3D G3DSA:3.40.630.10 23 406 1.7E-138 T 14-10-2018 TSH58p_25665 7f9d3793d601bccab85970e074734b93 418 PIRSF PIRSF001235 6 415 2.4E-129 T 14-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 TSH58p_25665 7f9d3793d601bccab85970e074734b93 418 SUPERFAMILY SSF55031 211 330 2.09E-28 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TSH58p_25665 7f9d3793d601bccab85970e074734b93 418 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 74 83 - T 14-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 TSH58p_25665 7f9d3793d601bccab85970e074734b93 418 Pfam PF07687 Peptidase dimerisation domain 209 306 1.2E-4 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain TSH58p_25665 7f9d3793d601bccab85970e074734b93 418 Gene3D G3DSA:3.30.70.360 211 330 1.7E-138 T 14-10-2018 TSH58p_25665 7f9d3793d601bccab85970e074734b93 418 SUPERFAMILY SSF53187 9 411 3.59E-80 T 14-10-2018 TSH58p_25665 7f9d3793d601bccab85970e074734b93 418 Pfam PF01546 Peptidase family M20/M25/M40 75 409 2.5E-29 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 TSH58p_25665 7f9d3793d601bccab85970e074734b93 418 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 19 408 2.2E-116 T 14-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 TSH58p_22505 2c87dbbcb7f4643f1770835d853a8abf 586 SMART SM01016 5 94 1.3E-32 T 14-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TSH58p_22505 2c87dbbcb7f4643f1770835d853a8abf 586 Gene3D G3DSA:3.40.50.620 124 446 8.6E-146 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_22505 2c87dbbcb7f4643f1770835d853a8abf 586 SUPERFAMILY SSF52374 116 463 1.15E-79 T 14-10-2018 TSH58p_22505 2c87dbbcb7f4643f1770835d853a8abf 586 PRINTS PR01038 Arginyl-tRNA synthetase signature 123 138 6.4E-21 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TSH58p_22505 2c87dbbcb7f4643f1770835d853a8abf 586 PRINTS PR01038 Arginyl-tRNA synthetase signature 138 154 6.4E-21 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TSH58p_22505 2c87dbbcb7f4643f1770835d853a8abf 586 PRINTS PR01038 Arginyl-tRNA synthetase signature 162 175 6.4E-21 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TSH58p_22505 2c87dbbcb7f4643f1770835d853a8abf 586 PRINTS PR01038 Arginyl-tRNA synthetase signature 321 342 6.4E-21 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TSH58p_22505 2c87dbbcb7f4643f1770835d853a8abf 586 SMART SM00836 452 584 9.7E-56 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 TSH58p_22505 2c87dbbcb7f4643f1770835d853a8abf 586 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 584 23.806 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TSH58p_22505 2c87dbbcb7f4643f1770835d853a8abf 586 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 12 583 8.1E-104 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TSH58p_22505 2c87dbbcb7f4643f1770835d853a8abf 586 Pfam PF05746 DALR anticodon binding domain 452 584 3.4E-32 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 TSH58p_22505 2c87dbbcb7f4643f1770835d853a8abf 586 Pfam PF00750 tRNA synthetases class I (R) 103 424 9.5E-14 T 14-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 TSH58p_22505 2c87dbbcb7f4643f1770835d853a8abf 586 Gene3D G3DSA:1.10.730.10 447 581 8.6E-146 T 14-10-2018 TSH58p_22505 2c87dbbcb7f4643f1770835d853a8abf 586 Gene3D G3DSA:3.30.1360.70 4 111 1.1E-22 T 14-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 TSH58p_22505 2c87dbbcb7f4643f1770835d853a8abf 586 SUPERFAMILY SSF55190 22 107 7.06E-22 T 14-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 TSH58p_22505 2c87dbbcb7f4643f1770835d853a8abf 586 SUPERFAMILY SSF47323 446 584 2.03E-34 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_22505 2c87dbbcb7f4643f1770835d853a8abf 586 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 9 94 8.9E-21 T 14-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TSH58p_00460 332017bd2b1f842e3e3a25b410be338d 377 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 122 134 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TSH58p_00460 332017bd2b1f842e3e3a25b410be338d 377 SUPERFAMILY SSF47203 226 376 2.58E-57 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TSH58p_00460 332017bd2b1f842e3e3a25b410be338d 377 PIRSF PIRSF016578 1 376 1.3E-22 T 14-10-2018 TSH58p_00460 332017bd2b1f842e3e3a25b410be338d 377 SUPERFAMILY SSF56645 2 240 6.68E-86 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TSH58p_00460 332017bd2b1f842e3e3a25b410be338d 377 Gene3D G3DSA:1.20.140.10 233 377 1.3E-56 T 14-10-2018 TSH58p_00460 332017bd2b1f842e3e3a25b410be338d 377 Gene3D G3DSA:1.10.540.10 1 118 2.3E-46 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TSH58p_00460 332017bd2b1f842e3e3a25b410be338d 377 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 334 353 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TSH58p_00460 332017bd2b1f842e3e3a25b410be338d 377 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 215 5.2E-30 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TSH58p_00460 332017bd2b1f842e3e3a25b410be338d 377 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 116 8.4E-38 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TSH58p_00460 332017bd2b1f842e3e3a25b410be338d 377 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 375 1.7E-51 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TSH58p_00460 332017bd2b1f842e3e3a25b410be338d 377 Gene3D G3DSA:2.40.110.10 119 232 5.2E-44 T 14-10-2018 TSH58p_19250 fa85bb68be3ca23d9ca913f2d24d2b1a 263 Gene3D G3DSA:3.40.50.2300 1 124 2.3E-11 T 14-10-2018 TSH58p_19250 fa85bb68be3ca23d9ca913f2d24d2b1a 263 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 223 2.2E-20 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_19250 fa85bb68be3ca23d9ca913f2d24d2b1a 263 SMART SM00862 146 223 7.8E-23 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_19250 fa85bb68be3ca23d9ca913f2d24d2b1a 263 SUPERFAMILY SSF46894 120 225 8.79E-22 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_19250 fa85bb68be3ca23d9ca913f2d24d2b1a 263 SUPERFAMILY SSF52172 1 134 2.05E-10 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_19250 fa85bb68be3ca23d9ca913f2d24d2b1a 263 Gene3D G3DSA:1.10.10.10 125 236 2.8E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_08045 0706659ea1f78e86ac7a65ef426c3e87 108 Gene3D G3DSA:3.30.1390.10 4 108 2.4E-44 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like TSH58p_08045 0706659ea1f78e86ac7a65ef426c3e87 108 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 25 104 3.5E-36 T 14-10-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 TSH58p_08045 0706659ea1f78e86ac7a65ef426c3e87 108 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 12 103 29.102 T 14-10-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS TSH58p_08045 0706659ea1f78e86ac7a65ef426c3e87 108 SUPERFAMILY SSF54736 23 107 3.4E-33 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like TSH58p_13225 ab9eeecdb0b0177ee03a15c8f177656e 69 SMART SM00357 3 69 3.8E-26 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 TSH58p_13225 ab9eeecdb0b0177ee03a15c8f177656e 69 PIRSF PIRSF002599 1 69 2.4E-22 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 TSH58p_13225 ab9eeecdb0b0177ee03a15c8f177656e 69 SUPERFAMILY SSF50249 1 68 2.14E-23 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_13225 ab9eeecdb0b0177ee03a15c8f177656e 69 PRINTS PR00050 Cold shock protein signature 4 19 3.4E-13 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_13225 ab9eeecdb0b0177ee03a15c8f177656e 69 PRINTS PR00050 Cold shock protein signature 40 58 3.4E-13 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_13225 ab9eeecdb0b0177ee03a15c8f177656e 69 PRINTS PR00050 Cold shock protein signature 25 34 3.4E-13 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_13225 ab9eeecdb0b0177ee03a15c8f177656e 69 Pfam PF00313 'Cold-shock' DNA-binding domain 4 67 1.5E-24 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_13225 ab9eeecdb0b0177ee03a15c8f177656e 69 Gene3D G3DSA:2.40.50.140 3 67 4.4E-25 T 14-10-2018 TSH58p_13225 ab9eeecdb0b0177ee03a15c8f177656e 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 14-10-2018 IPR019844 Cold-shock conserved site TSH58p_29700 8d753f3941404d9bff15b5c402b1a1a3 249 Pfam PF00035 Double-stranded RNA binding motif 178 243 8.4E-15 T 14-10-2018 IPR014720 Double-stranded RNA-binding domain TSH58p_29700 8d753f3941404d9bff15b5c402b1a1a3 249 Pfam PF14622 Ribonuclease-III-like 31 163 2.5E-29 T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 TSH58p_29700 8d753f3941404d9bff15b5c402b1a1a3 249 SUPERFAMILY SSF54768 133 245 2.04E-27 T 14-10-2018 TSH58p_29700 8d753f3941404d9bff15b5c402b1a1a3 249 Gene3D G3DSA:1.10.1520.10 13 170 3.6E-39 T 14-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 TSH58p_29700 8d753f3941404d9bff15b5c402b1a1a3 249 Hamap MF_00104 Ribonuclease 3 [rnc]. 17 240 26.869 T 14-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 TSH58p_29700 8d753f3941404d9bff15b5c402b1a1a3 249 SMART SM00358 177 244 1.7E-22 T 14-10-2018 IPR014720 Double-stranded RNA-binding domain TSH58p_29700 8d753f3941404d9bff15b5c402b1a1a3 249 ProSitePatterns PS00517 Ribonuclease III family signature. 61 69 - T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 TSH58p_29700 8d753f3941404d9bff15b5c402b1a1a3 249 SUPERFAMILY SSF69065 10 169 1.74E-41 T 14-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 TSH58p_29700 8d753f3941404d9bff15b5c402b1a1a3 249 Gene3D G3DSA:3.30.160.20 176 248 1.2E-20 T 14-10-2018 TSH58p_29700 8d753f3941404d9bff15b5c402b1a1a3 249 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 19 243 1.2E-64 T 14-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 TSH58p_29700 8d753f3941404d9bff15b5c402b1a1a3 249 SMART SM00535 29 172 1.2E-43 T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 TSH58p_01670 20699a7ea34b9c9b388f2db298488d68 719 Pfam PF07715 TonB-dependent Receptor Plug Domain 76 180 3.1E-19 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain TSH58p_01670 20699a7ea34b9c9b388f2db298488d68 719 Gene3D G3DSA:2.170.130.10 63 191 9.4E-28 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily TSH58p_01670 20699a7ea34b9c9b388f2db298488d68 719 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 702 719 - T 14-10-2018 IPR010917 TonB-dependent receptor, conserved site TSH58p_01670 20699a7ea34b9c9b388f2db298488d68 719 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 77 719 9.8E-88 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 TSH58p_01670 20699a7ea34b9c9b388f2db298488d68 719 Pfam PF00593 TonB dependent receptor 261 716 6.2E-51 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel TSH58p_01670 20699a7ea34b9c9b388f2db298488d68 719 Gene3D G3DSA:2.40.170.20 192 719 1.5E-104 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily TSH58p_01670 20699a7ea34b9c9b388f2db298488d68 719 SUPERFAMILY SSF56935 30 719 5.16E-130 T 14-10-2018 TSH58p_00705 16151fce465da50cacd3ce39403fd8c0 584 Gene3D G3DSA:3.40.190.10 184 503 7.9E-43 T 14-10-2018 TSH58p_00705 16151fce465da50cacd3ce39403fd8c0 584 SUPERFAMILY SSF53850 64 512 4.03E-55 T 14-10-2018 TSH58p_00705 16151fce465da50cacd3ce39403fd8c0 584 Gene3D G3DSA:3.40.190.10 81 460 7.9E-43 T 14-10-2018 TSH58p_00705 16151fce465da50cacd3ce39403fd8c0 584 PIRSF PIRSF035859 2 577 0.0 T 14-10-2018 IPR014597 ABC transporter, periplasmic substrate-binding protein, predicted GO:0005215 TSH58p_21825 8c939abcc55a1b271b9c925f3d52b9ec 377 Pfam PF00583 Acetyltransferase (GNAT) family 30 122 7.8E-18 T 14-10-2018 IPR000182 GNAT domain TSH58p_21825 8c939abcc55a1b271b9c925f3d52b9ec 377 Pfam PF11814 Peptidase_C39 like family 159 363 7.6E-85 T 14-10-2018 IPR021770 Protein of unknown function DUF3335 TSH58p_21825 8c939abcc55a1b271b9c925f3d52b9ec 377 SUPERFAMILY SSF55729 2 145 1.05E-33 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_21825 8c939abcc55a1b271b9c925f3d52b9ec 377 Gene3D G3DSA:3.40.630.30 1 148 1.3E-36 T 14-10-2018 TSH58p_21825 8c939abcc55a1b271b9c925f3d52b9ec 377 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 10 137 1.5E-25 T 14-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 TSH58p_12300 b2cd3ed0a2223cf0d0a570582e8e40dd 328 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 281 37.187 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSH58p_12300 b2cd3ed0a2223cf0d0a570582e8e40dd 328 Gene3D G3DSA:3.90.226.10 25 283 2.1E-77 T 14-10-2018 TSH58p_12300 b2cd3ed0a2223cf0d0a570582e8e40dd 328 SUPERFAMILY SSF52096 25 281 1.72E-81 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_12300 b2cd3ed0a2223cf0d0a570582e8e40dd 328 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 251 260 8.0E-37 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSH58p_12300 b2cd3ed0a2223cf0d0a570582e8e40dd 328 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 229 240 8.0E-37 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSH58p_12300 b2cd3ed0a2223cf0d0a570582e8e40dd 328 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 163 181 8.0E-37 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSH58p_12300 b2cd3ed0a2223cf0d0a570582e8e40dd 328 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 129 143 8.0E-37 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSH58p_12300 b2cd3ed0a2223cf0d0a570582e8e40dd 328 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 200 217 8.0E-37 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSH58p_12300 b2cd3ed0a2223cf0d0a570582e8e40dd 328 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 15 281 2.2E-108 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSH58p_12300 b2cd3ed0a2223cf0d0a570582e8e40dd 328 Pfam PF01039 Carboxyl transferase domain 93 241 9.9E-20 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 TSH58p_30440 d46c4aee61771b96f813027ecf396359 256 SMART SM00382 33 230 5.2E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_30440 d46c4aee61771b96f813027ecf396359 256 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 233 255 9.3E-12 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSH58p_30440 d46c4aee61771b96f813027ecf396359 256 SUPERFAMILY SSF52540 9 254 2.0E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_30440 d46c4aee61771b96f813027ecf396359 256 Gene3D G3DSA:3.40.50.300 4 253 5.1E-60 T 14-10-2018 TSH58p_30440 d46c4aee61771b96f813027ecf396359 256 Pfam PF00005 ABC transporter 25 185 1.2E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_16030 baea05371d3bb1c1837305f141d63939 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 146 158 2.3E-152 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16030 baea05371d3bb1c1837305f141d63939 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 258 279 2.3E-152 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16030 baea05371d3bb1c1837305f141d63939 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 304 319 2.3E-152 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16030 baea05371d3bb1c1837305f141d63939 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 328 349 2.3E-152 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16030 baea05371d3bb1c1837305f141d63939 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 104 128 2.3E-152 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16030 baea05371d3bb1c1837305f141d63939 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 178 196 2.3E-152 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16030 baea05371d3bb1c1837305f141d63939 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 28 53 2.3E-152 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16030 baea05371d3bb1c1837305f141d63939 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 207 226 2.3E-152 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16030 baea05371d3bb1c1837305f141d63939 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 76 99 2.3E-152 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16030 baea05371d3bb1c1837305f141d63939 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 441 462 2.3E-152 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16030 baea05371d3bb1c1837305f141d63939 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 391 410 2.3E-152 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16030 baea05371d3bb1c1837305f141d63939 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 363 381 2.3E-152 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16030 baea05371d3bb1c1837305f141d63939 537 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 37 482 2.3E-156 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16030 baea05371d3bb1c1837305f141d63939 537 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 260 314 - T 14-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16030 baea05371d3bb1c1837305f141d63939 537 SUPERFAMILY SSF81442 26 536 7.46E-222 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16030 baea05371d3bb1c1837305f141d63939 537 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 29 536 1.3E-218 T 14-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 TSH58p_16030 baea05371d3bb1c1837305f141d63939 537 Gene3D G3DSA:1.20.210.10 24 537 2.9E-246 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_24970 0ad82521637e5a4a56134ed1874c20b8 295 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 23 287 1.7E-93 T 14-10-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 TSH58p_24970 0ad82521637e5a4a56134ed1874c20b8 295 SUPERFAMILY SSF161098 34 285 4.95E-55 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_24970 0ad82521637e5a4a56134ed1874c20b8 295 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 27 290 2.3E-124 T 14-10-2018 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 TSH58p_24970 0ad82521637e5a4a56134ed1874c20b8 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 291 5.0E-28 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_24970 0ad82521637e5a4a56134ed1874c20b8 295 Gene3D G3DSA:1.10.3720.10 31 293 3.4E-66 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_04680 4749af9b043cfc31ddd554f585a3f69c 152 Pfam PF02391 MoaE protein 6 118 2.1E-34 T 14-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 TSH58p_04680 4749af9b043cfc31ddd554f585a3f69c 152 Gene3D G3DSA:3.90.1170.40 1 148 1.1E-49 T 14-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 TSH58p_04680 4749af9b043cfc31ddd554f585a3f69c 152 SUPERFAMILY SSF54690 3 148 4.84E-50 T 14-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 TSH58p_03845 fdfb186c0cfe83974214a100a9e35257 572 Pfam PF00501 AMP-binding enzyme 43 471 1.8E-104 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_03845 fdfb186c0cfe83974214a100a9e35257 572 Pfam PF13193 AMP-binding enzyme C-terminal domain 482 556 4.5E-18 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSH58p_03845 fdfb186c0cfe83974214a100a9e35257 572 Gene3D G3DSA:3.40.50.12780 31 468 3.8E-121 T 14-10-2018 TSH58p_03845 fdfb186c0cfe83974214a100a9e35257 572 SUPERFAMILY SSF56801 21 565 6.15E-151 T 14-10-2018 TSH58p_03845 fdfb186c0cfe83974214a100a9e35257 572 ProSitePatterns PS00455 Putative AMP-binding domain signature. 223 234 - T 14-10-2018 IPR020845 AMP-binding, conserved site TSH58p_03845 fdfb186c0cfe83974214a100a9e35257 572 Gene3D G3DSA:3.30.300.310 469 569 8.8E-27 T 14-10-2018 TSH58p_18725 43658e3fefc088d5e54518e4bc16549b 256 Gene3D G3DSA:3.20.20.70 1 255 4.6E-108 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_18725 43658e3fefc088d5e54518e4bc16549b 256 Pfam PF05690 Thiazole biosynthesis protein ThiG 7 249 1.3E-104 T 14-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 TSH58p_18725 43658e3fefc088d5e54518e4bc16549b 256 SUPERFAMILY SSF110399 3 241 4.45E-81 T 14-10-2018 TSH58p_18725 43658e3fefc088d5e54518e4bc16549b 256 Hamap MF_00443 Thiazole synthase [thiG]. 4 255 41.993 T 14-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 TSH58p_12375 effdfd69dc52a295c18fe23c9db8b50f 543 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 294 407 5.5E-31 T 14-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_12375 effdfd69dc52a295c18fe23c9db8b50f 543 SUPERFAMILY SSF53738 183 291 2.59E-30 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_12375 effdfd69dc52a295c18fe23c9db8b50f 543 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 442 503 1.8E-6 T 14-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_12375 effdfd69dc52a295c18fe23c9db8b50f 543 Gene3D G3DSA:3.40.120.10 291 409 2.5E-46 T 14-10-2018 TSH58p_12375 effdfd69dc52a295c18fe23c9db8b50f 543 Gene3D G3DSA:3.40.120.10 189 290 5.1E-36 T 14-10-2018 TSH58p_12375 effdfd69dc52a295c18fe23c9db8b50f 543 SUPERFAMILY SSF53738 5 212 6.28E-47 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_12375 effdfd69dc52a295c18fe23c9db8b50f 543 Gene3D G3DSA:3.30.310.50 410 543 3.2E-42 T 14-10-2018 TSH58p_12375 effdfd69dc52a295c18fe23c9db8b50f 543 SUPERFAMILY SSF55957 409 543 6.28E-42 T 14-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_12375 effdfd69dc52a295c18fe23c9db8b50f 543 SUPERFAMILY SSF53738 278 414 1.49E-36 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_12375 effdfd69dc52a295c18fe23c9db8b50f 543 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 14 153 6.6E-33 T 14-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_12375 effdfd69dc52a295c18fe23c9db8b50f 543 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 107 116 - T 14-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_12375 effdfd69dc52a295c18fe23c9db8b50f 543 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 184 286 3.3E-15 T 14-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_12375 effdfd69dc52a295c18fe23c9db8b50f 543 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 106 120 3.2E-23 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_12375 effdfd69dc52a295c18fe23c9db8b50f 543 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 205 224 3.2E-23 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_12375 effdfd69dc52a295c18fe23c9db8b50f 543 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 241 254 3.2E-23 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_12375 effdfd69dc52a295c18fe23c9db8b50f 543 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 270 285 3.2E-23 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSH58p_12375 effdfd69dc52a295c18fe23c9db8b50f 543 Gene3D G3DSA:3.40.120.10 2 188 9.3E-78 T 14-10-2018 TSH58p_06930 00d8c7d8f34296bffb9c10ca9fe0c731 560 Pfam PF00563 EAL domain 306 535 6.3E-55 T 14-10-2018 IPR001633 EAL domain TSH58p_06930 00d8c7d8f34296bffb9c10ca9fe0c731 560 SUPERFAMILY SSF55785 14 108 1.92E-7 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_06930 00d8c7d8f34296bffb9c10ca9fe0c731 560 SUPERFAMILY SSF141868 305 536 1.23E-61 T 14-10-2018 IPR035919 EAL domain superfamily TSH58p_06930 00d8c7d8f34296bffb9c10ca9fe0c731 560 Gene3D G3DSA:3.20.20.450 304 552 9.5E-64 T 14-10-2018 IPR035919 EAL domain superfamily TSH58p_06930 00d8c7d8f34296bffb9c10ca9fe0c731 560 SMART SM00052 299 540 2.2E-54 T 14-10-2018 IPR001633 EAL domain TSH58p_01030 38628e04d0c8928fb35e3e28c0c47702 440 Gene3D G3DSA:3.30.1540.10 279 370 1.2E-142 T 14-10-2018 TSH58p_01030 38628e04d0c8928fb35e3e28c0c47702 440 SUPERFAMILY SSF89796 50 440 3.79E-140 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily TSH58p_01030 38628e04d0c8928fb35e3e28c0c47702 440 Pfam PF02515 CoA-transferase family III 53 417 2.4E-131 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 TSH58p_01030 38628e04d0c8928fb35e3e28c0c47702 440 Gene3D G3DSA:3.40.50.10540 52 434 1.2E-142 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily TSH58p_06660 fb3e7e9bc94c70a1a41fc23c1206da30 385 Gene3D G3DSA:3.40.50.720 3 374 1.7E-139 T 14-10-2018 TSH58p_06660 fb3e7e9bc94c70a1a41fc23c1206da30 385 Gene3D G3DSA:3.40.50.720 145 328 1.7E-139 T 14-10-2018 TSH58p_06660 fb3e7e9bc94c70a1a41fc23c1206da30 385 SUPERFAMILY SSF51735 145 327 5.43E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_06660 fb3e7e9bc94c70a1a41fc23c1206da30 385 SMART SM01002 154 321 7.2E-88 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain TSH58p_06660 fb3e7e9bc94c70a1a41fc23c1206da30 385 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 149 377 2.0E-74 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain TSH58p_06660 fb3e7e9bc94c70a1a41fc23c1206da30 385 SUPERFAMILY SSF52283 1 176 2.21E-50 T 14-10-2018 TSH58p_06660 fb3e7e9bc94c70a1a41fc23c1206da30 385 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 178 203 - T 14-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 TSH58p_06660 fb3e7e9bc94c70a1a41fc23c1206da30 385 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 5 145 7.8E-42 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal TSH58p_06660 fb3e7e9bc94c70a1a41fc23c1206da30 385 SMART SM01003 4 145 4.7E-65 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal TSH58p_26995 d477875fe78dd888629bb414fbf85393 99 Gene3D G3DSA:2.30.30.90 16 98 1.0E-24 T 14-10-2018 IPR038157 Ferrous iron transporter, core domain TSH58p_26995 d477875fe78dd888629bb414fbf85393 99 SMART SM00899 16 97 1.0E-17 T 14-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 TSH58p_26995 d477875fe78dd888629bb414fbf85393 99 Pfam PF04023 FeoA domain 17 96 3.2E-20 T 14-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 TSH58p_26995 d477875fe78dd888629bb414fbf85393 99 SUPERFAMILY SSF50037 20 97 4.81E-14 T 14-10-2018 IPR008988 Transcriptional repressor, C-terminal TSH58p_06130 235cb9f8aea369e70ab1aa984a0d2734 511 Gene3D G3DSA:3.40.50.300 3 237 2.2E-63 T 14-10-2018 TSH58p_06130 235cb9f8aea369e70ab1aa984a0d2734 511 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_06130 235cb9f8aea369e70ab1aa984a0d2734 511 ProSitePatterns PS00211 ABC transporters family signature. 403 417 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_06130 235cb9f8aea369e70ab1aa984a0d2734 511 Pfam PF00005 ABC transporter 273 430 2.1E-10 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_06130 235cb9f8aea369e70ab1aa984a0d2734 511 Pfam PF00005 ABC transporter 24 168 1.9E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_06130 235cb9f8aea369e70ab1aa984a0d2734 511 SUPERFAMILY SSF52540 7 225 9.8E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_06130 235cb9f8aea369e70ab1aa984a0d2734 511 SUPERFAMILY SSF52540 253 487 5.97E-35 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_06130 235cb9f8aea369e70ab1aa984a0d2734 511 SMART SM00382 32 224 3.5E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_06130 235cb9f8aea369e70ab1aa984a0d2734 511 Gene3D G3DSA:3.40.50.300 256 493 1.7E-33 T 14-10-2018 TSH58p_04515 0167569d52057a972b346a748495c052 388 Gene3D G3DSA:2.60.410.10 279 369 5.6E-21 T 14-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TSH58p_04515 0167569d52057a972b346a748495c052 388 SMART SM00936 279 369 4.6E-27 T 14-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TSH58p_04515 0167569d52057a972b346a748495c052 388 SUPERFAMILY SSF69189 279 371 1.71E-20 T 14-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TSH58p_04515 0167569d52057a972b346a748495c052 388 SUPERFAMILY SSF56601 11 279 1.88E-76 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TSH58p_04515 0167569d52057a972b346a748495c052 388 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 33 255 2.7E-71 T 14-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 TSH58p_04515 0167569d52057a972b346a748495c052 388 Gene3D G3DSA:3.40.710.10 30 278 1.5E-80 T 14-10-2018 TSH58p_04515 0167569d52057a972b346a748495c052 388 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 146 159 4.4E-15 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 TSH58p_04515 0167569d52057a972b346a748495c052 388 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 119 136 4.4E-15 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 TSH58p_04515 0167569d52057a972b346a748495c052 388 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 66 77 4.4E-15 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 TSH58p_04515 0167569d52057a972b346a748495c052 388 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 279 369 1.1E-16 T 14-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TSH58p_02965 2144af73401ffae0f9c89f3d0b2d6052 299 Gene3D G3DSA:1.10.3720.10 27 295 3.9E-55 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_02965 2144af73401ffae0f9c89f3d0b2d6052 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 284 2.4E-7 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_02965 2144af73401ffae0f9c89f3d0b2d6052 299 SUPERFAMILY SSF161098 26 289 2.24E-50 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_08135 fe50a082dc310cf1be81d44992a9c1c8 149 Pfam PF01575 MaoC like domain 28 127 3.0E-27 T 14-10-2018 IPR002539 MaoC-like dehydratase domain TSH58p_08135 fe50a082dc310cf1be81d44992a9c1c8 149 SUPERFAMILY SSF54637 13 148 1.39E-45 T 14-10-2018 IPR029069 HotDog domain superfamily TSH58p_08135 fe50a082dc310cf1be81d44992a9c1c8 149 Gene3D G3DSA:3.10.129.10 7 148 4.4E-47 T 14-10-2018 TSH58p_14885 ca574dae88761c06a509d68a4e419028 779 Pfam PF02493 MORN repeat 652 674 4.9E-7 T 14-10-2018 IPR003409 MORN motif TSH58p_14885 ca574dae88761c06a509d68a4e419028 779 Pfam PF02493 MORN repeat 698 720 0.57 T 14-10-2018 IPR003409 MORN motif TSH58p_14885 ca574dae88761c06a509d68a4e419028 779 Pfam PF02493 MORN repeat 605 618 5.0 T 14-10-2018 IPR003409 MORN motif TSH58p_14885 ca574dae88761c06a509d68a4e419028 779 Pfam PF02493 MORN repeat 638 650 1.4 T 14-10-2018 IPR003409 MORN motif TSH58p_14885 ca574dae88761c06a509d68a4e419028 779 Pfam PF02493 MORN repeat 675 696 2.9E-4 T 14-10-2018 IPR003409 MORN motif TSH58p_14885 ca574dae88761c06a509d68a4e419028 779 SMART SM00698 696 717 2.7 T 14-10-2018 IPR003409 MORN motif TSH58p_14885 ca574dae88761c06a509d68a4e419028 779 SMART SM00698 617 648 0.53 T 14-10-2018 IPR003409 MORN motif TSH58p_14885 ca574dae88761c06a509d68a4e419028 779 SMART SM00698 650 671 6.3E-4 T 14-10-2018 IPR003409 MORN motif TSH58p_14885 ca574dae88761c06a509d68a4e419028 779 SMART SM00698 673 694 0.6 T 14-10-2018 IPR003409 MORN motif TSH58p_14885 ca574dae88761c06a509d68a4e419028 779 Pfam PF08239 Bacterial SH3 domain 430 481 2.2E-6 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type TSH58p_14885 ca574dae88761c06a509d68a4e419028 779 Pfam PF08239 Bacterial SH3 domain 337 388 4.1E-12 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type TSH58p_14885 ca574dae88761c06a509d68a4e419028 779 SUPERFAMILY SSF52129 18 268 1.03E-23 T 14-10-2018 IPR029030 Caspase-like domain superfamily TSH58p_14885 ca574dae88761c06a509d68a4e419028 779 Pfam PF00656 Caspase domain 38 257 3.4E-14 T 14-10-2018 TSH58p_14885 ca574dae88761c06a509d68a4e419028 779 Gene3D G3DSA:2.20.110.10 602 678 5.2E-10 T 14-10-2018 TSH58p_14885 ca574dae88761c06a509d68a4e419028 779 Gene3D G3DSA:2.20.110.10 679 769 6.6E-10 T 14-10-2018 TSH58p_14885 ca574dae88761c06a509d68a4e419028 779 Gene3D G3DSA:2.30.30.40 329 389 1.4E-11 T 14-10-2018 TSH58p_14885 ca574dae88761c06a509d68a4e419028 779 SMART SM00287 328 392 0.017 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type TSH58p_14885 ca574dae88761c06a509d68a4e419028 779 SMART SM00287 421 484 0.042 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type TSH58p_14885 ca574dae88761c06a509d68a4e419028 779 Gene3D G3DSA:3.40.50.1460 27 268 6.4E-29 T 14-10-2018 TSH58p_14885 ca574dae88761c06a509d68a4e419028 779 SUPERFAMILY SSF82185 650 772 5.69E-25 T 14-10-2018 TSH58p_19290 bf250cf1d96c14805beb9c26d1de8014 318 Gene3D G3DSA:3.90.420.10 64 318 4.8E-109 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 TSH58p_19290 bf250cf1d96c14805beb9c26d1de8014 318 SUPERFAMILY SSF56524 70 314 1.44E-92 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 TSH58p_19290 bf250cf1d96c14805beb9c26d1de8014 318 Pfam PF00174 Oxidoreductase molybdopterin binding domain 103 256 1.1E-32 T 14-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 TSH58p_19290 bf250cf1d96c14805beb9c26d1de8014 318 Hamap MF_01206 Protein-methionine-sulfoxide reductase catalytic subunit MsrP [msrP]. 9 318 56.609 T 14-10-2018 IPR022867 Protein-methionine-sulfoxide reductase subunit MsrP GO:0016667|GO:0030091|GO:0043546|GO:0055114 TSH58p_00730 39b9b0cf5426717e7ddd11837cf5d057 367 Gene3D G3DSA:3.40.50.300 3 213 2.8E-48 T 14-10-2018 TSH58p_00730 39b9b0cf5426717e7ddd11837cf5d057 367 Pfam PF00005 ABC transporter 18 160 4.2E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_00730 39b9b0cf5426717e7ddd11837cf5d057 367 Gene3D G3DSA:2.40.50.940 219 351 2.1E-12 T 14-10-2018 TSH58p_00730 39b9b0cf5426717e7ddd11837cf5d057 367 Gene3D G3DSA:2.40.50.140 281 343 2.1E-12 T 14-10-2018 TSH58p_00730 39b9b0cf5426717e7ddd11837cf5d057 367 SUPERFAMILY SSF50331 236 358 2.93E-17 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSH58p_00730 39b9b0cf5426717e7ddd11837cf5d057 367 SUPERFAMILY SSF52540 4 243 1.72E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_00730 39b9b0cf5426717e7ddd11837cf5d057 367 SMART SM00382 27 287 3.6E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_18480 f1b71d07a2d45f829e03e78e948785ed 220 Gene3D G3DSA:3.40.50.150 4 156 2.7E-15 T 14-10-2018 TSH58p_18480 f1b71d07a2d45f829e03e78e948785ed 220 Pfam PF08241 Methyltransferase domain 56 108 2.1E-8 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TSH58p_18480 f1b71d07a2d45f829e03e78e948785ed 220 SUPERFAMILY SSF53335 4 119 1.26E-16 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_17805 f1b71d07a2d45f829e03e78e948785ed 220 Gene3D G3DSA:3.40.50.150 4 156 2.7E-15 T 14-10-2018 TSH58p_17805 f1b71d07a2d45f829e03e78e948785ed 220 Pfam PF08241 Methyltransferase domain 56 108 2.1E-8 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TSH58p_17805 f1b71d07a2d45f829e03e78e948785ed 220 SUPERFAMILY SSF53335 4 119 1.26E-16 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_15185 94af2bc12bf6d3fe3dbc998c42d651ed 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 91 4.1E-42 T 14-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 TSH58p_15185 94af2bc12bf6d3fe3dbc998c42d651ed 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 1.6E-20 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15185 94af2bc12bf6d3fe3dbc998c42d651ed 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 1.6E-20 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15185 94af2bc12bf6d3fe3dbc998c42d651ed 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 1.6E-20 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15185 94af2bc12bf6d3fe3dbc998c42d651ed 92 PIRSF PIRSF002144 1 92 7.9E-34 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15185 94af2bc12bf6d3fe3dbc998c42d651ed 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 14-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15185 94af2bc12bf6d3fe3dbc998c42d651ed 92 Gene3D G3DSA:3.30.860.10 1 92 8.4E-39 T 14-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15185 94af2bc12bf6d3fe3dbc998c42d651ed 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 24.695 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15185 94af2bc12bf6d3fe3dbc998c42d651ed 92 Pfam PF00203 Ribosomal protein S19 3 83 5.2E-35 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15185 94af2bc12bf6d3fe3dbc998c42d651ed 92 SUPERFAMILY SSF54570 3 84 2.49E-34 T 14-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_31770 576c71db000f5b7c191d4dd45d636e92 287 SUPERFAMILY SSF161098 13 274 4.45E-51 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_31770 576c71db000f5b7c191d4dd45d636e92 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 269 1.2E-7 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_31770 576c71db000f5b7c191d4dd45d636e92 287 Gene3D G3DSA:1.10.3720.10 11 281 1.2E-56 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_27680 4df2de8f3ef48da932faafb3e6a63bb7 415 Pfam PF00999 Sodium/hydrogen exchanger family 9 408 2.1E-54 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TSH58p_27680 4df2de8f3ef48da932faafb3e6a63bb7 415 Gene3D G3DSA:1.20.1530.20 3 412 3.1E-11 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily TSH58p_25545 b5e9666d2956f57160e5447255b431c7 559 SUPERFAMILY SSF52540 3 229 3.71E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_25545 b5e9666d2956f57160e5447255b431c7 559 Gene3D G3DSA:3.40.50.300 1 237 6.6E-61 T 14-10-2018 TSH58p_25545 b5e9666d2956f57160e5447255b431c7 559 Gene3D G3DSA:3.40.50.300 298 550 2.7E-58 T 14-10-2018 TSH58p_25545 b5e9666d2956f57160e5447255b431c7 559 TIGRFAM TIGR01184 ntrCD: nitrate ABC transporter, ATP-binding proteins C and D 320 548 4.5E-96 T 14-10-2018 IPR005890 Nitrate transport ATP-binding subunit C/D GO:0015112|GO:0015706|GO:0016020 TSH58p_25545 b5e9666d2956f57160e5447255b431c7 559 SMART SM00382 328 510 2.4E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_25545 b5e9666d2956f57160e5447255b431c7 559 SMART SM00382 28 210 4.4E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_25545 b5e9666d2956f57160e5447255b431c7 559 Pfam PF00005 ABC transporter 320 460 6.0E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_25545 b5e9666d2956f57160e5447255b431c7 559 SUPERFAMILY SSF52540 300 520 1.13E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_25545 b5e9666d2956f57160e5447255b431c7 559 Pfam PF00005 ABC transporter 19 160 3.0E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_25545 b5e9666d2956f57160e5447255b431c7 559 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_25755 13ee91f1526121c19474e4186e38c767 574 Pfam PF04724 Glycosyltransferase family 17 292 533 2.0E-31 T 14-10-2018 IPR006813 Glycosyl transferase, family 17 GO:0003830|GO:0006487|GO:0016020 KEGG: 00510+2.4.1.144|MetaCyc: PWY-7426|Reactome: R-HSA-975574 TSH58p_04040 3fc116a2c7b7c4a627cc13ad297c7e1b 90 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 38 90 7.0E-21 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_04040 3fc116a2c7b7c4a627cc13ad297c7e1b 90 TIGRFAM TIGR00165 S18: ribosomal protein bS18 21 89 4.7E-31 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_04040 3fc116a2c7b7c4a627cc13ad297c7e1b 90 Pfam PF01084 Ribosomal protein S18 37 85 3.7E-26 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_04040 3fc116a2c7b7c4a627cc13ad297c7e1b 90 ProSitePatterns PS00057 Ribosomal protein S18 signature. 38 61 - T 14-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_04040 3fc116a2c7b7c4a627cc13ad297c7e1b 90 SUPERFAMILY SSF46911 17 90 8.24E-29 T 14-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_04040 3fc116a2c7b7c4a627cc13ad297c7e1b 90 Gene3D G3DSA:4.10.640.10 9 90 3.1E-29 T 14-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_04040 3fc116a2c7b7c4a627cc13ad297c7e1b 90 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 19 90 22.336 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_04040 3fc116a2c7b7c4a627cc13ad297c7e1b 90 PRINTS PR00974 Ribosomal protein S18 family signature 77 87 6.7E-19 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_04040 3fc116a2c7b7c4a627cc13ad297c7e1b 90 PRINTS PR00974 Ribosomal protein S18 family signature 55 62 6.7E-19 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_04040 3fc116a2c7b7c4a627cc13ad297c7e1b 90 PRINTS PR00974 Ribosomal protein S18 family signature 63 77 6.7E-19 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_04040 3fc116a2c7b7c4a627cc13ad297c7e1b 90 PRINTS PR00974 Ribosomal protein S18 family signature 45 55 6.7E-19 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_03050 e5d04dcd24dfbf768445fb704623995c 700 Pfam PF01568 Molydopterin dinucleotide binding domain 580 683 2.1E-22 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TSH58p_03050 e5d04dcd24dfbf768445fb704623995c 700 SUPERFAMILY SSF50692 571 697 1.97E-31 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TSH58p_03050 e5d04dcd24dfbf768445fb704623995c 700 SUPERFAMILY SSF53706 11 581 4.19E-139 T 14-10-2018 TSH58p_03050 e5d04dcd24dfbf768445fb704623995c 700 Gene3D G3DSA:2.40.40.20 557 700 1.5E-25 T 14-10-2018 TSH58p_03050 e5d04dcd24dfbf768445fb704623995c 700 Gene3D G3DSA:3.30.2070.10 437 519 1.5E-112 T 14-10-2018 TSH58p_03050 e5d04dcd24dfbf768445fb704623995c 700 Gene3D G3DSA:2.20.25.90 6 68 1.7E-7 T 14-10-2018 TSH58p_03050 e5d04dcd24dfbf768445fb704623995c 700 Gene3D G3DSA:3.40.50.740 77 482 1.5E-112 T 14-10-2018 TSH58p_03050 e5d04dcd24dfbf768445fb704623995c 700 SMART SM00926 7 63 1.9E-14 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_03050 e5d04dcd24dfbf768445fb704623995c 700 Pfam PF00384 Molybdopterin oxidoreductase 66 477 3.6E-47 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_03050 e5d04dcd24dfbf768445fb704623995c 700 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 11 63 4.0E-7 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_03050 e5d04dcd24dfbf768445fb704623995c 700 Gene3D G3DSA:3.40.228.10 143 521 1.5E-112 T 14-10-2018 TSH58p_06820 62c4205e126bb3efe35d7d1e7ba444eb 551 ProSitePatterns PS00455 Putative AMP-binding domain signature. 193 204 - T 14-10-2018 IPR020845 AMP-binding, conserved site TSH58p_06820 62c4205e126bb3efe35d7d1e7ba444eb 551 Gene3D G3DSA:3.40.50.12780 11 445 3.4E-107 T 14-10-2018 TSH58p_06820 62c4205e126bb3efe35d7d1e7ba444eb 551 Pfam PF13193 AMP-binding enzyme C-terminal domain 459 533 8.4E-24 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSH58p_06820 62c4205e126bb3efe35d7d1e7ba444eb 551 SUPERFAMILY SSF56801 18 544 4.71E-141 T 14-10-2018 TSH58p_06820 62c4205e126bb3efe35d7d1e7ba444eb 551 Gene3D G3DSA:3.30.300.310 446 549 1.0E-35 T 14-10-2018 TSH58p_06820 62c4205e126bb3efe35d7d1e7ba444eb 551 Pfam PF00501 AMP-binding enzyme 30 450 1.4E-95 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_05190 0f483fd68ae66872317aa43f07ebd19c 390 SUPERFAMILY SSF52283 1 176 2.72E-51 T 14-10-2018 TSH58p_05190 0f483fd68ae66872317aa43f07ebd19c 390 SMART SM01003 4 145 3.1E-66 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal TSH58p_05190 0f483fd68ae66872317aa43f07ebd19c 390 Gene3D G3DSA:3.40.50.720 145 328 1.5E-139 T 14-10-2018 TSH58p_05190 0f483fd68ae66872317aa43f07ebd19c 390 SMART SM01002 154 321 7.2E-88 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain TSH58p_05190 0f483fd68ae66872317aa43f07ebd19c 390 ProSitePatterns PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. 4 30 - T 14-10-2018 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 GO:0016491|GO:0055114 Reactome: R-HSA-71403 TSH58p_05190 0f483fd68ae66872317aa43f07ebd19c 390 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 178 203 - T 14-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 TSH58p_05190 0f483fd68ae66872317aa43f07ebd19c 390 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 149 377 1.8E-74 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain TSH58p_05190 0f483fd68ae66872317aa43f07ebd19c 390 Gene3D G3DSA:3.40.50.720 3 374 1.5E-139 T 14-10-2018 TSH58p_05190 0f483fd68ae66872317aa43f07ebd19c 390 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 5 145 4.6E-42 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal TSH58p_05190 0f483fd68ae66872317aa43f07ebd19c 390 SUPERFAMILY SSF51735 145 327 5.48E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_26640 146a98c173bd6b221534676c2f825a64 433 Gene3D G3DSA:1.20.1600.10 1 407 5.2E-67 T 14-10-2018 TSH58p_26640 146a98c173bd6b221534676c2f825a64 433 Pfam PF02321 Outer membrane efflux protein 8 185 1.0E-22 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 TSH58p_26640 146a98c173bd6b221534676c2f825a64 433 Pfam PF02321 Outer membrane efflux protein 209 393 1.5E-22 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 TSH58p_26640 146a98c173bd6b221534676c2f825a64 433 SUPERFAMILY SSF56954 2 400 9.42E-60 T 14-10-2018 TSH58p_19610 aa598f7e6e0fac4a4a0fa30c8155df27 399 Pfam PF01546 Peptidase family M20/M25/M40 79 390 9.6E-35 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 TSH58p_19610 aa598f7e6e0fac4a4a0fa30c8155df27 399 SUPERFAMILY SSF55031 190 303 1.7E-31 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TSH58p_19610 aa598f7e6e0fac4a4a0fa30c8155df27 399 Gene3D G3DSA:3.40.630.10 21 377 1.6E-135 T 14-10-2018 TSH58p_19610 aa598f7e6e0fac4a4a0fa30c8155df27 399 PIRSF PIRSF005962 6 396 2.6E-124 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 TSH58p_19610 aa598f7e6e0fac4a4a0fa30c8155df27 399 Pfam PF07687 Peptidase dimerisation domain 193 288 3.4E-11 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain TSH58p_19610 aa598f7e6e0fac4a4a0fa30c8155df27 399 SUPERFAMILY SSF53187 12 395 2.45E-86 T 14-10-2018 TSH58p_19610 aa598f7e6e0fac4a4a0fa30c8155df27 399 Gene3D G3DSA:3.30.70.360 188 302 1.6E-135 T 14-10-2018 TSH58p_19610 aa598f7e6e0fac4a4a0fa30c8155df27 399 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 20 381 1.2E-108 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 TSH58p_20975 a82e8f63527cefca7edf7685f65b0bf1 150 Gene3D G3DSA:3.40.30.10 1 141 4.1E-60 T 14-10-2018 TSH58p_20975 a82e8f63527cefca7edf7685f65b0bf1 150 SUPERFAMILY SSF52833 4 135 6.38E-41 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_20975 a82e8f63527cefca7edf7685f65b0bf1 150 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 4 116 4.2E-44 T 14-10-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 TSH58p_20975 a82e8f63527cefca7edf7685f65b0bf1 150 Pfam PF03960 ArsC family 7 114 2.1E-18 T 14-10-2018 IPR006660 Arsenate reductase-like TSH58p_20000 4862e6560dd7c5dcca9123290553589f 886 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 718 738 - T 14-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 TSH58p_20000 4862e6560dd7c5dcca9123290553589f 886 PIRSF PIRSF000111 1 862 0.0 T 14-10-2018 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 TSH58p_20000 4862e6560dd7c5dcca9123290553589f 886 Gene3D G3DSA:3.40.309.10 218 404 6.1E-178 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TSH58p_20000 4862e6560dd7c5dcca9123290553589f 886 SUPERFAMILY SSF56796 449 863 1.28E-116 T 14-10-2018 TSH58p_20000 4862e6560dd7c5dcca9123290553589f 886 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 630 658 - T 14-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 TSH58p_20000 4862e6560dd7c5dcca9123290553589f 886 Gene3D G3DSA:3.40.50.1970 450 641 3.4E-54 T 14-10-2018 TSH58p_20000 4862e6560dd7c5dcca9123290553589f 886 Gene3D G3DSA:1.20.1090.10 643 861 3.6E-65 T 14-10-2018 TSH58p_20000 4862e6560dd7c5dcca9123290553589f 886 Pfam PF00465 Iron-containing alcohol dehydrogenase 457 848 1.4E-113 T 14-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 TSH58p_20000 4862e6560dd7c5dcca9123290553589f 886 Gene3D G3DSA:3.40.605.10 12 445 6.1E-178 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TSH58p_20000 4862e6560dd7c5dcca9123290553589f 886 SUPERFAMILY SSF53720 6 453 9.16E-79 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSH58p_20000 4862e6560dd7c5dcca9123290553589f 886 Pfam PF00171 Aldehyde dehydrogenase family 4 269 8.1E-24 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TSH58p_24510 c40a4c64e060678f8215404592016f44 562 Gene3D G3DSA:1.25.40.10 117 318 8.5E-16 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_24510 c40a4c64e060678f8215404592016f44 562 Gene3D G3DSA:1.25.40.10 7 115 9.0E-20 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_24510 c40a4c64e060678f8215404592016f44 562 SUPERFAMILY SSF48452 10 178 7.11E-27 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_24510 c40a4c64e060678f8215404592016f44 562 Pfam PF13432 Tetratricopeptide repeat 16 72 5.3E-8 T 14-10-2018 TSH58p_24510 c40a4c64e060678f8215404592016f44 562 Pfam PF13432 Tetratricopeptide repeat 111 174 1.6E-6 T 14-10-2018 TSH58p_24510 c40a4c64e060678f8215404592016f44 562 SMART SM00028 106 139 23.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24510 c40a4c64e060678f8215404592016f44 562 SMART SM00028 38 71 1.5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24510 c40a4c64e060678f8215404592016f44 562 SMART SM00028 72 105 12.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24510 c40a4c64e060678f8215404592016f44 562 SMART SM00028 140 173 0.24 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29030 3a2632f473d774b0d640e6ce6357b100 472 Pfam PF00224 Pyruvate kinase, barrel domain 5 335 4.0E-111 T 14-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_29030 3a2632f473d774b0d640e6ce6357b100 472 Gene3D G3DSA:3.40.1380.20 333 466 1.0E-167 T 14-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_29030 3a2632f473d774b0d640e6ce6357b100 472 SUPERFAMILY SSF50800 73 168 7.33E-23 T 14-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily TSH58p_29030 3a2632f473d774b0d640e6ce6357b100 472 PRINTS PR01050 Pyruvate kinase family signature 291 309 1.7E-63 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_29030 3a2632f473d774b0d640e6ce6357b100 472 PRINTS PR01050 Pyruvate kinase family signature 310 326 1.7E-63 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_29030 3a2632f473d774b0d640e6ce6357b100 472 PRINTS PR01050 Pyruvate kinase family signature 62 78 1.7E-63 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_29030 3a2632f473d774b0d640e6ce6357b100 472 PRINTS PR01050 Pyruvate kinase family signature 214 240 1.7E-63 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_29030 3a2632f473d774b0d640e6ce6357b100 472 PRINTS PR01050 Pyruvate kinase family signature 266 290 1.7E-63 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_29030 3a2632f473d774b0d640e6ce6357b100 472 PRINTS PR01050 Pyruvate kinase family signature 241 265 1.7E-63 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_29030 3a2632f473d774b0d640e6ce6357b100 472 PRINTS PR01050 Pyruvate kinase family signature 187 201 1.7E-63 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_29030 3a2632f473d774b0d640e6ce6357b100 472 Gene3D G3DSA:2.40.33.10 73 169 1.0E-167 T 14-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_29030 3a2632f473d774b0d640e6ce6357b100 472 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 5 470 2.3E-152 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_29030 3a2632f473d774b0d640e6ce6357b100 472 Gene3D G3DSA:3.20.20.60 5 332 1.0E-167 T 14-10-2018 TSH58p_29030 3a2632f473d774b0d640e6ce6357b100 472 SUPERFAMILY SSF51621 2 340 1.36E-93 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSH58p_29030 3a2632f473d774b0d640e6ce6357b100 472 Pfam PF02887 Pyruvate kinase, alpha/beta domain 355 468 3.5E-31 T 14-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_29030 3a2632f473d774b0d640e6ce6357b100 472 SUPERFAMILY SSF52935 320 470 4.19E-40 T 14-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_20335 d03d5104e54907d6792534bc51e3503b 344 Hamap MF_00070 2-keto-3-deoxygluconate permease [kdgT]. 1 318 33.416 T 14-10-2018 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 TSH58p_20335 d03d5104e54907d6792534bc51e3503b 344 TIGRFAM TIGR00793 kdgT: 2-keto-3-deoxygluconate transporter 1 312 8.9E-144 T 14-10-2018 IPR018395 2-keto-3-deoxygluconate permease, subgroup GO:0008643|GO:0015649|GO:0016021|GO:0046411 TSH58p_20335 d03d5104e54907d6792534bc51e3503b 344 ProDom PD024513 PERMEASE 2-KETO-3-DEOXYGLUCONATE MEMBRANE TRANSMEMBRANE SUGAR KDG SYMPORT INNER 2-KETO-3-DEOXY-D-GLUCONATE SYSTEM 14 245 3.0E-60 T 14-10-2018 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 TSH58p_20335 d03d5104e54907d6792534bc51e3503b 344 Pfam PF03812 2-keto-3-deoxygluconate permease 3 312 3.8E-114 T 14-10-2018 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 TSH58p_07435 93dcf263f6a08ccb6facf9f56b356c48 370 SUPERFAMILY SSF81901 68 186 5.1E-24 T 14-10-2018 TSH58p_07435 93dcf263f6a08ccb6facf9f56b356c48 370 Gene3D G3DSA:1.25.40.10 186 363 2.1E-40 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_07435 93dcf263f6a08ccb6facf9f56b356c48 370 Gene3D G3DSA:1.25.40.10 65 185 1.3E-30 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_07435 93dcf263f6a08ccb6facf9f56b356c48 370 SMART SM00671 241 276 1.0E-7 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07435 93dcf263f6a08ccb6facf9f56b356c48 370 SMART SM00671 91 126 0.0015 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07435 93dcf263f6a08ccb6facf9f56b356c48 370 SMART SM00671 277 312 0.018 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07435 93dcf263f6a08ccb6facf9f56b356c48 370 SMART SM00671 313 348 28.0 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07435 93dcf263f6a08ccb6facf9f56b356c48 370 SMART SM00671 163 204 0.019 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07435 93dcf263f6a08ccb6facf9f56b356c48 370 SMART SM00671 205 240 2.8E-5 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07435 93dcf263f6a08ccb6facf9f56b356c48 370 SMART SM00671 127 162 7.5E-5 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07435 93dcf263f6a08ccb6facf9f56b356c48 370 SMART SM00671 47 90 66.0 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07435 93dcf263f6a08ccb6facf9f56b356c48 370 SUPERFAMILY SSF81901 187 358 3.05E-35 T 14-10-2018 TSH58p_07435 93dcf263f6a08ccb6facf9f56b356c48 370 Pfam PF08238 Sel1 repeat 243 276 1.4E-5 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07435 93dcf263f6a08ccb6facf9f56b356c48 370 Pfam PF08238 Sel1 repeat 67 89 0.061 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07435 93dcf263f6a08ccb6facf9f56b356c48 370 Pfam PF08238 Sel1 repeat 206 240 0.0013 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07435 93dcf263f6a08ccb6facf9f56b356c48 370 Pfam PF08238 Sel1 repeat 279 310 0.0035 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07435 93dcf263f6a08ccb6facf9f56b356c48 370 Pfam PF08238 Sel1 repeat 127 162 2.2E-4 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07435 93dcf263f6a08ccb6facf9f56b356c48 370 Pfam PF08238 Sel1 repeat 92 126 0.001 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_07435 93dcf263f6a08ccb6facf9f56b356c48 370 Pfam PF08238 Sel1 repeat 165 204 0.01 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_02145 527a35d1ef37c636b06997618b4de7c1 239 SUPERFAMILY SSF46785 6 96 8.82E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_02145 527a35d1ef37c636b06997618b4de7c1 239 SMART SM00345 17 75 1.7E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_02145 527a35d1ef37c636b06997618b4de7c1 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 75 2.1E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_02145 527a35d1ef37c636b06997618b4de7c1 239 SUPERFAMILY SSF48008 81 214 1.49E-23 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_02145 527a35d1ef37c636b06997618b4de7c1 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 2.9E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_02145 527a35d1ef37c636b06997618b4de7c1 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 2.9E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_02145 527a35d1ef37c636b06997618b4de7c1 239 Pfam PF07729 FCD domain 89 208 2.5E-22 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_02145 527a35d1ef37c636b06997618b4de7c1 239 Gene3D G3DSA:1.10.10.10 11 76 9.8E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_02145 527a35d1ef37c636b06997618b4de7c1 239 SMART SM00895 85 209 6.0E-16 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_02145 527a35d1ef37c636b06997618b4de7c1 239 Gene3D G3DSA:1.20.120.530 78 216 6.8E-24 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_25915 ae8cbb74e7fabb16b6f37e1be00aab30 446 SUPERFAMILY SSF47413 24 94 2.19E-6 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_25915 ae8cbb74e7fabb16b6f37e1be00aab30 446 Pfam PF13464 Domain of unknown function (DUF4115) 359 428 6.2E-16 T 14-10-2018 IPR025194 Domain of unknown function DUF4115 TSH58p_25915 ae8cbb74e7fabb16b6f37e1be00aab30 446 SMART SM00530 27 88 4.1E-5 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_25915 ae8cbb74e7fabb16b6f37e1be00aab30 446 Gene3D G3DSA:1.10.260.40 18 106 2.1E-25 T 14-10-2018 TSH58p_25915 ae8cbb74e7fabb16b6f37e1be00aab30 446 Pfam PF13413 Helix-turn-helix domain 28 87 7.4E-23 T 14-10-2018 TSH58p_25915 ae8cbb74e7fabb16b6f37e1be00aab30 446 PRINTS PR01217 Proline rich extensin signature 210 226 4.2E-9 T 14-10-2018 TSH58p_25915 ae8cbb74e7fabb16b6f37e1be00aab30 446 PRINTS PR01217 Proline rich extensin signature 230 247 4.2E-9 T 14-10-2018 TSH58p_25915 ae8cbb74e7fabb16b6f37e1be00aab30 446 PRINTS PR01217 Proline rich extensin signature 181 202 4.2E-9 T 14-10-2018 TSH58p_25915 ae8cbb74e7fabb16b6f37e1be00aab30 446 PRINTS PR01217 Proline rich extensin signature 252 277 4.2E-9 T 14-10-2018 TSH58p_25915 ae8cbb74e7fabb16b6f37e1be00aab30 446 PRINTS PR01217 Proline rich extensin signature 102 114 4.2E-9 T 14-10-2018 TSH58p_10845 29271cf3fdc5f07c93c2196f08cdf607 326 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 41 155 5.1E-15 T 14-10-2018 IPR000014 PAS domain TSH58p_10845 29271cf3fdc5f07c93c2196f08cdf607 326 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 156 319 2.4E-54 T 14-10-2018 IPR000160 GGDEF domain TSH58p_10845 29271cf3fdc5f07c93c2196f08cdf607 326 SUPERFAMILY SSF55073 164 320 5.34E-52 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_10845 29271cf3fdc5f07c93c2196f08cdf607 326 Gene3D G3DSA:3.30.70.270 157 323 2.4E-61 T 14-10-2018 TSH58p_10845 29271cf3fdc5f07c93c2196f08cdf607 326 Pfam PF13426 PAS domain 47 147 1.2E-11 T 14-10-2018 IPR000014 PAS domain TSH58p_10845 29271cf3fdc5f07c93c2196f08cdf607 326 SMART SM00267 148 320 4.7E-68 T 14-10-2018 IPR000160 GGDEF domain TSH58p_10845 29271cf3fdc5f07c93c2196f08cdf607 326 SUPERFAMILY SSF55785 51 157 5.76E-16 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_10845 29271cf3fdc5f07c93c2196f08cdf607 326 Pfam PF00990 Diguanylate cyclase, GGDEF domain 160 316 6.6E-48 T 14-10-2018 IPR000160 GGDEF domain TSH58p_10845 29271cf3fdc5f07c93c2196f08cdf607 326 SMART SM00091 36 101 9.3E-6 T 14-10-2018 IPR000014 PAS domain TSH58p_10845 29271cf3fdc5f07c93c2196f08cdf607 326 Gene3D G3DSA:3.30.450.20 34 156 1.0E-15 T 14-10-2018 TSH58p_20915 4ca6aa00f57ea5572c9b28967cf02705 298 Gene3D G3DSA:3.20.20.60 7 297 2.5E-83 T 14-10-2018 TSH58p_20915 4ca6aa00f57ea5572c9b28967cf02705 298 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 18 235 1.9E-37 T 14-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 TSH58p_20915 4ca6aa00f57ea5572c9b28967cf02705 298 SUPERFAMILY SSF51621 16 246 1.12E-58 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSH58p_20915 4ca6aa00f57ea5572c9b28967cf02705 298 PIRSF PIRSF015582 2 298 4.9E-72 T 14-10-2018 IPR011206 Citrate lyase beta subunit-like TSH58p_03625 2d54311e636974f1d5b8c7d9423e3ac5 280 Gene3D G3DSA:1.10.101.10 213 279 9.4E-15 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 TSH58p_03625 2d54311e636974f1d5b8c7d9423e3ac5 280 Pfam PF01471 Putative peptidoglycan binding domain 222 275 1.7E-13 T 14-10-2018 IPR002477 Peptidoglycan binding-like TSH58p_03625 2d54311e636974f1d5b8c7d9423e3ac5 280 SUPERFAMILY SSF47090 213 278 6.44E-16 T 14-10-2018 IPR036365 PGBD-like superfamily TSH58p_03625 2d54311e636974f1d5b8c7d9423e3ac5 280 Pfam PF11860 N-acetylmuramidase 41 207 6.8E-44 T 14-10-2018 IPR024408 N-acetylmuramidase TSH58p_19070 358652b7b153c35a1119200de5a34a00 252 SMART SM00895 97 221 6.9E-15 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_19070 358652b7b153c35a1119200de5a34a00 252 Gene3D G3DSA:1.10.10.10 25 88 5.2E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_19070 358652b7b153c35a1119200de5a34a00 252 Pfam PF00392 Bacterial regulatory proteins, gntR family 28 87 1.1E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_19070 358652b7b153c35a1119200de5a34a00 252 SUPERFAMILY SSF48008 100 223 1.28E-25 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_19070 358652b7b153c35a1119200de5a34a00 252 Pfam PF07729 FCD domain 101 220 3.6E-25 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_19070 358652b7b153c35a1119200de5a34a00 252 Gene3D G3DSA:1.20.120.530 96 232 1.6E-24 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_19070 358652b7b153c35a1119200de5a34a00 252 SMART SM00345 29 87 1.6E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_19070 358652b7b153c35a1119200de5a34a00 252 SUPERFAMILY SSF46785 26 91 7.52E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_20080 4ca3db81db53df6004421c156a94f8a1 298 Pfam PF03466 LysR substrate binding domain 95 296 6.7E-23 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_20080 4ca3db81db53df6004421c156a94f8a1 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 1.6E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_20080 4ca3db81db53df6004421c156a94f8a1 298 Gene3D G3DSA:3.40.190.10 169 269 6.8E-49 T 14-10-2018 TSH58p_20080 4ca3db81db53df6004421c156a94f8a1 298 Gene3D G3DSA:1.10.10.10 1 86 8.1E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_20080 4ca3db81db53df6004421c156a94f8a1 298 Gene3D G3DSA:3.40.190.10 94 293 6.8E-49 T 14-10-2018 TSH58p_20080 4ca3db81db53df6004421c156a94f8a1 298 SUPERFAMILY SSF46785 2 83 2.08E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_20080 4ca3db81db53df6004421c156a94f8a1 298 SUPERFAMILY SSF53850 95 296 2.9E-37 T 14-10-2018 TSH58p_10810 e596fb241cd011bd18251ff71f0f5ac8 169 Gene3D G3DSA:3.60.90.10 45 169 3.0E-39 T 14-10-2018 TSH58p_10810 e596fb241cd011bd18251ff71f0f5ac8 169 Pfam PF02675 S-adenosylmethionine decarboxylase 61 165 3.8E-35 T 14-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 TSH58p_10810 e596fb241cd011bd18251ff71f0f5ac8 169 SUPERFAMILY SSF56276 58 166 9.42E-34 T 14-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 TSH58p_10810 e596fb241cd011bd18251ff71f0f5ac8 169 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 58 165 6.2E-40 T 14-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 TSH58p_10810 e596fb241cd011bd18251ff71f0f5ac8 169 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 55 169 25.595 T 14-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 TSH58p_14670 d2a07fe4fb91d3931c54c348ae67ed7b 161 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 3 144 3.2E-44 T 14-10-2018 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 TSH58p_14670 d2a07fe4fb91d3931c54c348ae67ed7b 161 Pfam PF02470 MlaD protein 36 113 2.7E-20 T 14-10-2018 IPR003399 Mce/MlaD TSH58p_29095 f42939b0d269ae23dd25ce6c6b9afc3c 171 SUPERFAMILY SSF53271 1 167 3.02E-49 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like TSH58p_29095 f42939b0d269ae23dd25ce6c6b9afc3c 171 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 3 168 2.1E-61 T 14-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 TSH58p_29095 f42939b0d269ae23dd25ce6c6b9afc3c 171 Gene3D G3DSA:3.40.50.2020 1 171 2.5E-61 T 14-10-2018 TSH58p_29095 f42939b0d269ae23dd25ce6c6b9afc3c 171 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 169 35.736 T 14-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 TSH58p_29095 f42939b0d269ae23dd25ce6c6b9afc3c 171 Pfam PF00156 Phosphoribosyl transferase domain 32 147 2.5E-17 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TSH58p_18470 947379ad80ff8119f1e5e0245648fba7 241 SUPERFAMILY SSF51161 19 199 8.73E-36 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily TSH58p_18470 947379ad80ff8119f1e5e0245648fba7 241 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 136 164 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 TSH58p_18470 947379ad80ff8119f1e5e0245648fba7 241 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 128 162 1.3E-11 T 14-10-2018 IPR001451 Hexapeptide repeat TSH58p_18470 947379ad80ff8119f1e5e0245648fba7 241 Gene3D G3DSA:2.160.10.10 37 229 7.7E-52 T 14-10-2018 TSH58p_12800 0c6347bb50c150e9883bdcd37e151122 574 SUPERFAMILY SSF161098 309 561 1.14E-30 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_12800 0c6347bb50c150e9883bdcd37e151122 574 SUPERFAMILY SSF161098 31 287 3.79E-43 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_12800 0c6347bb50c150e9883bdcd37e151122 574 Gene3D G3DSA:1.10.3720.10 311 570 3.8E-26 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_12800 0c6347bb50c150e9883bdcd37e151122 574 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 281 5.5E-13 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_12800 0c6347bb50c150e9883bdcd37e151122 574 Gene3D G3DSA:1.10.3720.10 24 294 7.0E-53 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_20560 ae13bc7bb2cf3d68508fd84c7781f28a 307 Pfam PF02653 Branched-chain amino acid transport system / permease component 20 284 2.4E-35 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_22125 9680a549ba9f1461463d7e0689cef5c5 335 PIRSF PIRSF035875 21 320 3.7E-78 T 14-10-2018 IPR017039 Virulence factor BrkB TSH58p_22125 9680a549ba9f1461463d7e0689cef5c5 335 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 40 300 7.1E-30 T 14-10-2018 IPR017039 Virulence factor BrkB TSH58p_22125 9680a549ba9f1461463d7e0689cef5c5 335 Pfam PF03631 Virulence factor BrkB 48 303 4.2E-69 T 14-10-2018 IPR017039 Virulence factor BrkB TSH58p_25890 04f0fe76717b4ff29de5409fffcee99a 152 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 4 145 1.7E-34 T 14-10-2018 IPR002178 PTS EIIA type-2 domain TSH58p_25890 04f0fe76717b4ff29de5409fffcee99a 152 SUPERFAMILY SSF55804 3 144 4.71E-42 T 14-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 TSH58p_25890 04f0fe76717b4ff29de5409fffcee99a 152 TIGRFAM TIGR01419 nitro_reg_IIA: PTS IIA-like nitrogen-regulatory protein PtsN 3 144 3.5E-49 T 14-10-2018 IPR006320 Phosphotransferase system, IIA-like nitrogen-regulatory protein PtsN GO:0008982|GO:0009401 TSH58p_25890 04f0fe76717b4ff29de5409fffcee99a 152 Gene3D G3DSA:3.40.930.10 1 151 2.1E-50 T 14-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 TSH58p_25890 04f0fe76717b4ff29de5409fffcee99a 152 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 49 65 - T 14-10-2018 IPR002178 PTS EIIA type-2 domain TSH58p_25780 5d096727a86bc2dc4789537bcf1a1bfc 325 Gene3D G3DSA:3.40.190.10 109 210 1.2E-46 T 14-10-2018 TSH58p_25780 5d096727a86bc2dc4789537bcf1a1bfc 325 Pfam PF09084 NMT1/THI5 like 39 249 5.6E-46 T 14-10-2018 IPR015168 SsuA/THI5-like TSH58p_25780 5d096727a86bc2dc4789537bcf1a1bfc 325 SUPERFAMILY SSF53850 27 254 3.47E-38 T 14-10-2018 TSH58p_25780 5d096727a86bc2dc4789537bcf1a1bfc 325 Gene3D G3DSA:3.40.190.10 48 298 1.2E-46 T 14-10-2018 TSH58p_31305 b382e3974548126e81bd7d7ba81bea52 192 Gene3D G3DSA:3.40.50.360 1 191 9.8E-49 T 14-10-2018 IPR029039 Flavoprotein-like superfamily TSH58p_31305 b382e3974548126e81bd7d7ba81bea52 192 Pfam PF02525 Flavodoxin-like fold 1 186 2.6E-44 T 14-10-2018 IPR003680 Flavodoxin-like fold TSH58p_31305 b382e3974548126e81bd7d7ba81bea52 192 SUPERFAMILY SSF52218 1 189 2.0E-49 T 14-10-2018 IPR029039 Flavoprotein-like superfamily TSH58p_30815 f0c05a44e623f5d9aa1343d76ecf61ac 154 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 13 148 6.0E-15 T 14-10-2018 IPR009936 Protein of unknown function DUF1468 TSH58p_19285 d3e98789ce6706b9b8de61698af05799 346 Gene3D G3DSA:3.30.360.10 134 336 3.0E-80 T 14-10-2018 TSH58p_19285 d3e98789ce6706b9b8de61698af05799 346 SUPERFAMILY SSF55347 136 279 6.54E-27 T 14-10-2018 TSH58p_19285 d3e98789ce6706b9b8de61698af05799 346 SUPERFAMILY SSF51735 6 161 4.83E-41 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_19285 d3e98789ce6706b9b8de61698af05799 346 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 139 222 8.5E-7 T 14-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 TSH58p_19285 d3e98789ce6706b9b8de61698af05799 346 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 124 1.6E-26 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 TSH58p_19285 d3e98789ce6706b9b8de61698af05799 346 Gene3D G3DSA:3.40.50.720 8 317 3.0E-80 T 14-10-2018 TSH58p_26095 80622937e133c413637eeb32513385b4 362 Gene3D G3DSA:3.20.20.70 5 359 9.1E-126 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_26095 80622937e133c413637eeb32513385b4 362 Pfam PF01070 FMN-dependent dehydrogenase 20 356 8.1E-117 T 14-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 TSH58p_26095 80622937e133c413637eeb32513385b4 362 SUPERFAMILY SSF51395 7 357 3.72E-92 T 14-10-2018 TSH58p_26095 80622937e133c413637eeb32513385b4 362 PIRSF PIRSF000138 2 360 4.4E-114 T 14-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 TSH58p_07485 b762b219d606a42b0d14c486fed5da9e 417 SUPERFAMILY SSF56176 6 185 1.31E-27 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TSH58p_07485 b762b219d606a42b0d14c486fed5da9e 417 Gene3D G3DSA:3.30.465.10 58 184 2.5E-26 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TSH58p_07485 b762b219d606a42b0d14c486fed5da9e 417 Gene3D G3DSA:1.10.45.10 382 413 4.5E-5 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 TSH58p_07485 b762b219d606a42b0d14c486fed5da9e 417 SUPERFAMILY SSF55103 200 415 1.8E-20 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 TSH58p_07485 b762b219d606a42b0d14c486fed5da9e 417 Pfam PF01565 FAD binding domain 6 145 4.0E-15 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TSH58p_16200 5c37fef0eeafadf9c6482f6b344f4770 331 Gene3D G3DSA:3.40.50.720 129 297 1.0E-112 T 14-10-2018 TSH58p_16200 5c37fef0eeafadf9c6482f6b344f4770 331 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 92 1.6E-5 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TSH58p_16200 5c37fef0eeafadf9c6482f6b344f4770 331 SUPERFAMILY SSF51735 121 290 2.52E-32 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_16200 5c37fef0eeafadf9c6482f6b344f4770 331 SUPERFAMILY SSF50129 6 146 2.89E-37 T 14-10-2018 IPR011032 GroES-like superfamily TSH58p_16200 5c37fef0eeafadf9c6482f6b344f4770 331 SMART SM00829 19 327 2.5E-6 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TSH58p_16200 5c37fef0eeafadf9c6482f6b344f4770 331 Pfam PF00107 Zinc-binding dehydrogenase 163 274 1.2E-8 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TSH58p_16200 5c37fef0eeafadf9c6482f6b344f4770 331 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 7 329 6.4E-121 T 14-10-2018 IPR014188 Acrylyl-CoA reductase AcuI TSH58p_16200 5c37fef0eeafadf9c6482f6b344f4770 331 Gene3D G3DSA:3.90.180.10 23 327 1.0E-112 T 14-10-2018 TSH58p_19555 0fb064d55d2c7ba38ae802e8e1e6ac79 321 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 45 69 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TSH58p_19555 0fb064d55d2c7ba38ae802e8e1e6ac79 321 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 258 271 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TSH58p_19555 0fb064d55d2c7ba38ae802e8e1e6ac79 321 Pfam PF00294 pfkB family carbohydrate kinase 19 302 3.5E-51 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB TSH58p_19555 0fb064d55d2c7ba38ae802e8e1e6ac79 321 Gene3D G3DSA:3.40.1190.20 8 320 1.8E-96 T 14-10-2018 IPR029056 Ribokinase-like TSH58p_19555 0fb064d55d2c7ba38ae802e8e1e6ac79 321 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 11 317 9.1E-97 T 14-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 TSH58p_19555 0fb064d55d2c7ba38ae802e8e1e6ac79 321 SUPERFAMILY SSF53613 12 303 2.49E-61 T 14-10-2018 IPR029056 Ribokinase-like TSH58p_19555 0fb064d55d2c7ba38ae802e8e1e6ac79 321 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 11 317 8.6E-96 T 14-10-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 TSH58p_19555 0fb064d55d2c7ba38ae802e8e1e6ac79 321 PIRSF PIRSF000535 9 320 5.6E-89 T 14-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 TSH58p_10790 5aaec92415c3877108bd741fa5767c67 246 Gene3D G3DSA:3.40.50.720 2 246 6.3E-80 T 14-10-2018 TSH58p_10790 5aaec92415c3877108bd741fa5767c67 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 8.5E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_10790 5aaec92415c3877108bd741fa5767c67 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 8.5E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_10790 5aaec92415c3877108bd741fa5767c67 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 8.5E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_10790 5aaec92415c3877108bd741fa5767c67 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 245 4.8E-61 T 14-10-2018 TSH58p_10790 5aaec92415c3877108bd741fa5767c67 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 211 0.0018 T 14-10-2018 TSH58p_10790 5aaec92415c3877108bd741fa5767c67 246 SUPERFAMILY SSF51735 6 245 4.57E-80 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_10790 5aaec92415c3877108bd741fa5767c67 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.6E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_10790 5aaec92415c3877108bd741fa5767c67 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 1.6E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_10790 5aaec92415c3877108bd741fa5767c67 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.6E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_10790 5aaec92415c3877108bd741fa5767c67 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.6E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_10790 5aaec92415c3877108bd741fa5767c67 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.6E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_10790 5aaec92415c3877108bd741fa5767c67 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.6E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_05900 3af7eddb81a667bb186254baa52260fb 406 Gene3D G3DSA:1.10.645.20 20 406 3.5E-179 T 14-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05900 3af7eddb81a667bb186254baa52260fb 406 SUPERFAMILY SSF56762 32 406 6.02E-142 T 14-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05900 3af7eddb81a667bb186254baa52260fb 406 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 23 406 1.2E-182 T 14-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05900 3af7eddb81a667bb186254baa52260fb 406 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 136 406 7.9E-128 T 14-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05900 3af7eddb81a667bb186254baa52260fb 406 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 59 70 - T 14-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05900 3af7eddb81a667bb186254baa52260fb 406 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 13 406 49.174 T 14-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_26445 312592492c95801c0c7bef0124c44456 558 SMART SM00304 229 281 3.1E-6 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_26445 312592492c95801c0c7bef0124c44456 558 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 423 452 1.7E-15 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_26445 312592492c95801c0c7bef0124c44456 558 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 394 421 1.7E-15 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_26445 312592492c95801c0c7bef0124c44456 558 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 313 342 1.7E-15 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_26445 312592492c95801c0c7bef0124c44456 558 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 341 523 1.0E-30 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_26445 312592492c95801c0c7bef0124c44456 558 SUPERFAMILY SSF58104 249 558 3.66E-57 T 14-10-2018 TSH58p_26445 312592492c95801c0c7bef0124c44456 558 SMART SM00283 296 557 8.4E-39 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_26445 312592492c95801c0c7bef0124c44456 558 Gene3D G3DSA:1.10.287.950 229 558 8.8E-58 T 14-10-2018 TSH58p_03140 4fbf460c1b273da965bb3afe97328e87 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 268 4.2E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_03140 4fbf460c1b273da965bb3afe97328e87 277 Gene3D G3DSA:1.10.3720.10 3 264 1.9E-58 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_03140 4fbf460c1b273da965bb3afe97328e87 277 SUPERFAMILY SSF161098 4 277 2.62E-67 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_26980 7e276b37e1da2774f334ea14e5e9b8a3 376 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 120 3.0E-33 T 14-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 TSH58p_26980 7e276b37e1da2774f334ea14e5e9b8a3 376 SMART SM00480 17 372 4.3E-124 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 TSH58p_26980 7e276b37e1da2774f334ea14e5e9b8a3 376 SUPERFAMILY SSF55979 255 376 1.21E-35 T 14-10-2018 TSH58p_26980 7e276b37e1da2774f334ea14e5e9b8a3 376 SUPERFAMILY SSF55979 1 118 3.37E-26 T 14-10-2018 TSH58p_26980 7e276b37e1da2774f334ea14e5e9b8a3 376 Pfam PF02767 DNA polymerase III beta subunit, central domain 133 253 2.0E-31 T 14-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 TSH58p_26980 7e276b37e1da2774f334ea14e5e9b8a3 376 Gene3D G3DSA:3.10.150.10 1 252 2.0E-118 T 14-10-2018 TSH58p_26980 7e276b37e1da2774f334ea14e5e9b8a3 376 SUPERFAMILY SSF55979 128 254 3.14E-26 T 14-10-2018 TSH58p_26980 7e276b37e1da2774f334ea14e5e9b8a3 376 Gene3D G3DSA:3.70.10.10 139 374 2.0E-118 T 14-10-2018 TSH58p_26980 7e276b37e1da2774f334ea14e5e9b8a3 376 PIRSF PIRSF000804 1 376 9.6E-119 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 TSH58p_26980 7e276b37e1da2774f334ea14e5e9b8a3 376 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 256 375 6.1E-33 T 14-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 TSH58p_26980 7e276b37e1da2774f334ea14e5e9b8a3 376 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 375 1.7E-87 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 TSH58p_19345 738ec0f3ae5ec2fba64621f0d619d4de 319 Gene3D G3DSA:3.40.190.290 91 301 4.4E-38 T 14-10-2018 TSH58p_19345 738ec0f3ae5ec2fba64621f0d619d4de 319 SUPERFAMILY SSF53850 89 298 4.96E-37 T 14-10-2018 TSH58p_19345 738ec0f3ae5ec2fba64621f0d619d4de 319 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 3.0E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_19345 738ec0f3ae5ec2fba64621f0d619d4de 319 Gene3D G3DSA:1.10.10.10 1 90 8.9E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_19345 738ec0f3ae5ec2fba64621f0d619d4de 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.3E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_19345 738ec0f3ae5ec2fba64621f0d619d4de 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.3E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_19345 738ec0f3ae5ec2fba64621f0d619d4de 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.3E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_19345 738ec0f3ae5ec2fba64621f0d619d4de 319 SUPERFAMILY SSF46785 1 86 4.27E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_19345 738ec0f3ae5ec2fba64621f0d619d4de 319 Pfam PF03466 LysR substrate binding domain 87 294 7.1E-40 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_09590 7eaa7c2f2567df81fa8e0821c7b3cdbe 125 Gene3D G3DSA:3.40.50.12740 6 124 1.3E-38 T 14-10-2018 TSH58p_09590 7eaa7c2f2567df81fa8e0821c7b3cdbe 125 SUPERFAMILY SSF52172 7 124 1.57E-38 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_09590 7eaa7c2f2567df81fa8e0821c7b3cdbe 125 SMART SM00448 7 120 5.1E-38 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_09590 7eaa7c2f2567df81fa8e0821c7b3cdbe 125 Pfam PF00072 Response regulator receiver domain 9 120 1.7E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_19180 64711ab860c9634acc58cef3ff3c5f93 88 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 81 1.3E-26 T 14-10-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 TSH58p_19180 64711ab860c9634acc58cef3ff3c5f93 88 PIRSF PIRSF004669 1 88 8.6E-27 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 TSH58p_19180 64711ab860c9634acc58cef3ff3c5f93 88 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 2.1E-20 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 TSH58p_19180 64711ab860c9634acc58cef3ff3c5f93 88 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 2.1E-20 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 TSH58p_19180 64711ab860c9634acc58cef3ff3c5f93 88 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 2.1E-20 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 TSH58p_19180 64711ab860c9634acc58cef3ff3c5f93 88 Pfam PF01313 Bacterial export proteins, family 3 6 77 8.8E-27 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 TSH58p_23075 f062dbfae6127ff0f50c3ca4f05fcc78 457 Pfam PF00375 Sodium:dicarboxylate symporter family 22 412 1.6E-100 T 14-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 TSH58p_23075 f062dbfae6127ff0f50c3ca4f05fcc78 457 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 49 64 - T 14-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site TSH58p_23075 f062dbfae6127ff0f50c3ca4f05fcc78 457 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 308 331 - T 14-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site TSH58p_23075 f062dbfae6127ff0f50c3ca4f05fcc78 457 SUPERFAMILY SSF118215 22 415 6.02E-110 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 TSH58p_23075 f062dbfae6127ff0f50c3ca4f05fcc78 457 Gene3D G3DSA:1.10.3860.10 13 432 9.4E-112 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 TSH58p_23075 f062dbfae6127ff0f50c3ca4f05fcc78 457 PRINTS PR00173 Glutamate-aspartate symporter signature 340 359 7.1E-28 T 14-10-2018 TSH58p_23075 f062dbfae6127ff0f50c3ca4f05fcc78 457 PRINTS PR00173 Glutamate-aspartate symporter signature 305 331 7.1E-28 T 14-10-2018 TSH58p_23075 f062dbfae6127ff0f50c3ca4f05fcc78 457 PRINTS PR00173 Glutamate-aspartate symporter signature 16 36 7.1E-28 T 14-10-2018 TSH58p_23075 f062dbfae6127ff0f50c3ca4f05fcc78 457 PRINTS PR00173 Glutamate-aspartate symporter signature 57 77 7.1E-28 T 14-10-2018 TSH58p_23075 f062dbfae6127ff0f50c3ca4f05fcc78 457 PRINTS PR00173 Glutamate-aspartate symporter signature 87 112 7.1E-28 T 14-10-2018 TSH58p_26290 98cd0a1c1333d9848bee0df114766ea2 163 Pfam PF07475 HPr Serine kinase C-terminal domain 29 131 1.1E-17 T 14-10-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 TSH58p_26290 98cd0a1c1333d9848bee0df114766ea2 163 Gene3D G3DSA:3.40.50.300 27 157 2.8E-32 T 14-10-2018 TSH58p_26290 98cd0a1c1333d9848bee0df114766ea2 163 SUPERFAMILY SSF53795 29 123 1.68E-18 T 14-10-2018 TSH58p_22810 1ebfc6f7b072ad9203ae40c1654ec633 516 Pfam PF00958 GMP synthase C terminal domain 424 515 3.1E-46 T 14-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TSH58p_22810 1ebfc6f7b072ad9203ae40c1654ec633 516 Gene3D G3DSA:3.30.300.10 397 516 1.7E-54 T 14-10-2018 TSH58p_22810 1ebfc6f7b072ad9203ae40c1654ec633 516 PRINTS PR00097 Anthranilate synthase component II signature 77 88 1.7E-5 T 14-10-2018 TSH58p_22810 1ebfc6f7b072ad9203ae40c1654ec633 516 PRINTS PR00097 Anthranilate synthase component II signature 168 181 1.7E-5 T 14-10-2018 TSH58p_22810 1ebfc6f7b072ad9203ae40c1654ec633 516 Gene3D G3DSA:3.40.50.880 3 200 2.1E-51 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_22810 1ebfc6f7b072ad9203ae40c1654ec633 516 SUPERFAMILY SSF52317 4 228 3.54E-55 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_22810 1ebfc6f7b072ad9203ae40c1654ec633 516 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 204 516 4.0E-149 T 14-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TSH58p_22810 1ebfc6f7b072ad9203ae40c1654ec633 516 Pfam PF00117 Glutamine amidotransferase class-I 8 190 2.0E-36 T 14-10-2018 IPR017926 Glutamine amidotransferase TSH58p_22810 1ebfc6f7b072ad9203ae40c1654ec633 516 Pfam PF02540 NAD synthase 209 245 3.5E-6 T 14-10-2018 IPR022310 NAD/GMP synthase TSH58p_22810 1ebfc6f7b072ad9203ae40c1654ec633 516 Gene3D G3DSA:3.40.50.620 201 396 2.3E-75 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_22810 1ebfc6f7b072ad9203ae40c1654ec633 516 PRINTS PR00096 Glutamine amidotransferase superfamily signature 168 181 9.0E-8 T 14-10-2018 TSH58p_22810 1ebfc6f7b072ad9203ae40c1654ec633 516 PRINTS PR00096 Glutamine amidotransferase superfamily signature 50 59 9.0E-8 T 14-10-2018 TSH58p_22810 1ebfc6f7b072ad9203ae40c1654ec633 516 PRINTS PR00096 Glutamine amidotransferase superfamily signature 77 88 9.0E-8 T 14-10-2018 TSH58p_22810 1ebfc6f7b072ad9203ae40c1654ec633 516 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 6 194 2.2E-72 T 14-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TSH58p_22810 1ebfc6f7b072ad9203ae40c1654ec633 516 SUPERFAMILY SSF54810 396 516 3.27E-54 T 14-10-2018 TSH58p_22810 1ebfc6f7b072ad9203ae40c1654ec633 516 SUPERFAMILY SSF52402 188 409 8.16E-58 T 14-10-2018 TSH58p_22810 1ebfc6f7b072ad9203ae40c1654ec633 516 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 3 516 55.126 T 14-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 TSH58p_28455 de54bb19967bd5238040c91c0cd49fb3 465 SMART SM00267 282 456 3.0E-67 T 14-10-2018 IPR000160 GGDEF domain TSH58p_28455 de54bb19967bd5238040c91c0cd49fb3 465 Gene3D G3DSA:3.30.70.270 290 459 2.9E-60 T 14-10-2018 TSH58p_28455 de54bb19967bd5238040c91c0cd49fb3 465 Gene3D G3DSA:3.40.50.12740 1 289 1.9E-96 T 14-10-2018 TSH58p_28455 de54bb19967bd5238040c91c0cd49fb3 465 Pfam PF00990 Diguanylate cyclase, GGDEF domain 293 452 4.2E-50 T 14-10-2018 IPR000160 GGDEF domain TSH58p_28455 de54bb19967bd5238040c91c0cd49fb3 465 SMART SM00448 156 269 1.8E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_28455 de54bb19967bd5238040c91c0cd49fb3 465 SMART SM00448 3 116 8.9E-45 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_28455 de54bb19967bd5238040c91c0cd49fb3 465 SUPERFAMILY SSF55073 298 454 1.88E-51 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_28455 de54bb19967bd5238040c91c0cd49fb3 465 SUPERFAMILY SSF52172 2 132 5.69E-43 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_28455 de54bb19967bd5238040c91c0cd49fb3 465 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 292 454 9.1E-55 T 14-10-2018 IPR000160 GGDEF domain TSH58p_28455 de54bb19967bd5238040c91c0cd49fb3 465 SUPERFAMILY SSF52172 151 288 4.7E-28 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_28455 de54bb19967bd5238040c91c0cd49fb3 465 Pfam PF00072 Response regulator receiver domain 158 269 1.2E-17 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_28455 de54bb19967bd5238040c91c0cd49fb3 465 Pfam PF00072 Response regulator receiver domain 5 116 1.2E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_12835 b9740a2a1bec6db619dfe3e0add3cf76 194 Gene3D G3DSA:1.10.287.110 119 191 1.4E-12 T 14-10-2018 IPR036869 Chaperone J-domain superfamily TSH58p_12835 b9740a2a1bec6db619dfe3e0add3cf76 194 Pfam PF00226 DnaJ domain 140 189 6.1E-12 T 14-10-2018 IPR001623 DnaJ domain TSH58p_12835 b9740a2a1bec6db619dfe3e0add3cf76 194 SMART SM00271 135 193 1.1E-11 T 14-10-2018 IPR001623 DnaJ domain TSH58p_12835 b9740a2a1bec6db619dfe3e0add3cf76 194 SUPERFAMILY SSF46565 99 189 2.62E-16 T 14-10-2018 IPR036869 Chaperone J-domain superfamily TSH58p_28320 f2ffbbf8d3969f393bb1288ebbeac903 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_28320 f2ffbbf8d3969f393bb1288ebbeac903 253 SUPERFAMILY SSF51735 4 248 4.41E-56 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_28320 f2ffbbf8d3969f393bb1288ebbeac903 253 Gene3D G3DSA:3.40.50.720 3 251 5.0E-57 T 14-10-2018 TSH58p_28320 f2ffbbf8d3969f393bb1288ebbeac903 253 Pfam PF00106 short chain dehydrogenase 7 191 1.4E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_28320 f2ffbbf8d3969f393bb1288ebbeac903 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.5E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_28320 f2ffbbf8d3969f393bb1288ebbeac903 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.5E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_28320 f2ffbbf8d3969f393bb1288ebbeac903 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.5E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_28320 f2ffbbf8d3969f393bb1288ebbeac903 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 2.5E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_28320 f2ffbbf8d3969f393bb1288ebbeac903 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.5E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_28320 f2ffbbf8d3969f393bb1288ebbeac903 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.5E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_28320 f2ffbbf8d3969f393bb1288ebbeac903 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.5E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_28320 f2ffbbf8d3969f393bb1288ebbeac903 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 2.5E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_14820 5919e8d1a56add54d067560000735084 836 Pfam PF00905 Penicillin binding protein transpeptidase domain 438 732 8.4E-35 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 TSH58p_14820 5919e8d1a56add54d067560000735084 836 SUPERFAMILY SSF56601 214 782 8.88E-133 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TSH58p_14820 5919e8d1a56add54d067560000735084 836 SUPERFAMILY SSF53955 42 257 1.8E-71 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily TSH58p_14820 5919e8d1a56add54d067560000735084 836 Gene3D G3DSA:3.40.710.10 430 776 2.6E-105 T 14-10-2018 TSH58p_14820 5919e8d1a56add54d067560000735084 836 Pfam PF00912 Transglycosylase 55 232 1.3E-60 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_14820 5919e8d1a56add54d067560000735084 836 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 65 736 3.6E-186 T 14-10-2018 TSH58p_14820 5919e8d1a56add54d067560000735084 836 Gene3D G3DSA:3.40.710.10 254 328 1.7E-8 T 14-10-2018 TSH58p_14820 5919e8d1a56add54d067560000735084 836 Gene3D G3DSA:2.40.50.140 329 429 2.1E-15 T 14-10-2018 TSH58p_14820 5919e8d1a56add54d067560000735084 836 Gene3D G3DSA:1.10.3810.10 56 253 2.1E-72 T 14-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_14820 5919e8d1a56add54d067560000735084 836 Pfam PF17092 Penicillin-binding protein OB-like domain 320 436 4.2E-22 T 14-10-2018 IPR031376 Penicillin-binding protein, OB-like domain KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_23260 bd90911f68525ea9ae72421e83fe29a7 248 SUPERFAMILY SSF53850 21 242 1.53E-59 T 14-10-2018 TSH58p_23260 bd90911f68525ea9ae72421e83fe29a7 248 Gene3D G3DSA:3.40.190.10 27 242 1.2E-74 T 14-10-2018 TSH58p_23260 bd90911f68525ea9ae72421e83fe29a7 248 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 28 241 1.5E-69 T 14-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 TSH58p_23260 bd90911f68525ea9ae72421e83fe29a7 248 PIRSF PIRSF004846 1 246 1.0E-50 T 14-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 TSH58p_23260 bd90911f68525ea9ae72421e83fe29a7 248 Gene3D G3DSA:3.40.190.10 102 204 1.2E-74 T 14-10-2018 TSH58p_23260 bd90911f68525ea9ae72421e83fe29a7 248 Pfam PF13531 Bacterial extracellular solute-binding protein 24 242 1.1E-45 T 14-10-2018 TSH58p_13705 711defa25f895981f87ed96c9fbbfb59 152 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 151 28.093 T 14-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 TSH58p_13705 711defa25f895981f87ed96c9fbbfb59 152 Gene3D G3DSA:3.40.1280.10 1 151 9.4E-50 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TSH58p_13705 711defa25f895981f87ed96c9fbbfb59 152 PIRSF PIRSF004505 1 151 2.8E-44 T 14-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 TSH58p_13705 711defa25f895981f87ed96c9fbbfb59 152 Pfam PF02590 Predicted SPOUT methyltransferase 1 150 4.4E-47 T 14-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 TSH58p_13705 711defa25f895981f87ed96c9fbbfb59 152 SUPERFAMILY SSF75217 1 149 2.56E-47 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases TSH58p_10065 f055a5cf4ce9c496c680faa9ce79e45c 568 SUPERFAMILY SSF55874 397 561 7.99E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_10065 f055a5cf4ce9c496c680faa9ce79e45c 568 PRINTS PR00344 Bacterial sensor protein C-terminal signature 546 559 7.2E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_10065 f055a5cf4ce9c496c680faa9ce79e45c 568 PRINTS PR00344 Bacterial sensor protein C-terminal signature 509 519 7.2E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_10065 f055a5cf4ce9c496c680faa9ce79e45c 568 PRINTS PR00344 Bacterial sensor protein C-terminal signature 491 505 7.2E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_10065 f055a5cf4ce9c496c680faa9ce79e45c 568 PRINTS PR00344 Bacterial sensor protein C-terminal signature 522 540 7.2E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_10065 f055a5cf4ce9c496c680faa9ce79e45c 568 SUPERFAMILY SSF47384 322 396 1.59E-5 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_10065 f055a5cf4ce9c496c680faa9ce79e45c 568 Gene3D G3DSA:1.10.287.130 327 398 5.8E-13 T 14-10-2018 TSH58p_10065 f055a5cf4ce9c496c680faa9ce79e45c 568 Gene3D G3DSA:3.30.565.10 404 565 1.4E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_10065 f055a5cf4ce9c496c680faa9ce79e45c 568 SMART SM00387 441 562 2.0E-30 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_10065 f055a5cf4ce9c496c680faa9ce79e45c 568 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 442 560 8.5E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_01130 b4b649c66fe843a1ac4ec7a3ca53b956 234 PIRSF PIRSF015957 2 234 3.3E-44 T 14-10-2018 IPR007565 (5-formylfuran-3-yl)methyl phosphate synthase KEGG: 00680+4.2.3.153|MetaCyc: PWY-5254 TSH58p_01130 b4b649c66fe843a1ac4ec7a3ca53b956 234 Pfam PF04476 4-HFC-P synthase 4 223 2.6E-64 T 14-10-2018 IPR007565 (5-formylfuran-3-yl)methyl phosphate synthase KEGG: 00680+4.2.3.153|MetaCyc: PWY-5254 TSH58p_04245 1400dfb589fc94a9c3c18776bec7888a 252 SUPERFAMILY SSF53300 29 234 2.43E-18 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TSH58p_04245 1400dfb589fc94a9c3c18776bec7888a 252 Pfam PF06707 Protein of unknown function (DUF1194) 30 236 2.6E-76 T 14-10-2018 IPR010607 Protein of unknown function DUF1194 TSH58p_04245 1400dfb589fc94a9c3c18776bec7888a 252 Gene3D G3DSA:3.40.50.410 30 203 2.9E-13 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TSH58p_31780 641ffaf170cbaf458b787964d64afbd6 337 Gene3D G3DSA:3.10.310.10 8 335 4.0E-103 T 14-10-2018 TSH58p_31780 641ffaf170cbaf458b787964d64afbd6 337 SUPERFAMILY SSF54506 1 334 3.14E-93 T 14-10-2018 TSH58p_31780 641ffaf170cbaf458b787964d64afbd6 337 PIRSF PIRSF029792 1 337 4.4E-99 T 14-10-2018 IPR008794 Proline racemase family TSH58p_31780 641ffaf170cbaf458b787964d64afbd6 337 Gene3D G3DSA:3.10.310.10 147 313 4.0E-103 T 14-10-2018 TSH58p_31780 641ffaf170cbaf458b787964d64afbd6 337 Pfam PF05544 Proline racemase 11 334 3.7E-92 T 14-10-2018 IPR008794 Proline racemase family TSH58p_05330 b9271449a5d94fc0283bbfc2967b353a 403 SUPERFAMILY SSF103473 7 388 2.62E-52 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_05330 b9271449a5d94fc0283bbfc2967b353a 403 Gene3D G3DSA:1.20.1250.20 203 396 2.1E-18 T 14-10-2018 TSH58p_05330 b9271449a5d94fc0283bbfc2967b353a 403 Gene3D G3DSA:1.20.1250.20 6 187 2.1E-22 T 14-10-2018 TSH58p_05330 b9271449a5d94fc0283bbfc2967b353a 403 Pfam PF07690 Major Facilitator Superfamily 14 231 4.0E-24 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_18720 017ef2e00553cfdeb5b39103660de9db 147 Pfam PF03061 Thioesterase superfamily 55 130 3.4E-11 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TSH58p_18720 017ef2e00553cfdeb5b39103660de9db 147 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 25 124 2.5E-19 T 14-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 TSH58p_18720 017ef2e00553cfdeb5b39103660de9db 147 SUPERFAMILY SSF54637 10 141 2.81E-29 T 14-10-2018 IPR029069 HotDog domain superfamily TSH58p_18720 017ef2e00553cfdeb5b39103660de9db 147 Gene3D G3DSA:3.10.129.10 6 143 3.7E-33 T 14-10-2018 TSH58p_26605 aaebf45a7ace662cefa552d6b75ac9d5 991 Pfam PF14331 ImcF-related N-terminal domain 67 297 9.4E-28 T 14-10-2018 IPR025743 ImcF-related, N-terminal domain TSH58p_32100 a67ff82803016ebf38e4c18de123dc67 303 ProSitePatterns PS00398 Site-specific recombinases signature 2. 56 68 - T 14-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 TSH58p_32100 a67ff82803016ebf38e4c18de123dc67 303 Pfam PF00239 Resolvase, N terminal domain 4 136 2.0E-39 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 TSH58p_32100 a67ff82803016ebf38e4c18de123dc67 303 SMART SM00857 3 137 3.7E-52 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 TSH58p_32100 a67ff82803016ebf38e4c18de123dc67 303 Gene3D G3DSA:3.40.50.1390 2 126 1.0E-42 T 14-10-2018 TSH58p_32100 a67ff82803016ebf38e4c18de123dc67 303 SUPERFAMILY SSF53041 1 136 4.32E-39 T 14-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 TSH58p_32100 a67ff82803016ebf38e4c18de123dc67 303 ProSitePatterns PS00397 Site-specific recombinases active site. 6 14 - T 14-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 TSH58p_02685 489ff50411bf2ae0bd87ede1ad994c07 124 SUPERFAMILY SSF52172 5 121 7.12E-27 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_02685 489ff50411bf2ae0bd87ede1ad994c07 124 SMART SM00448 5 113 2.1E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_02685 489ff50411bf2ae0bd87ede1ad994c07 124 Gene3D G3DSA:3.40.50.2300 1 124 6.0E-25 T 14-10-2018 TSH58p_02685 489ff50411bf2ae0bd87ede1ad994c07 124 Pfam PF00072 Response regulator receiver domain 7 87 6.1E-16 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_13750 4a780046b0e055e2502e87f34ae159cd 92 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 84 28.516 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_13750 4a780046b0e055e2502e87f34ae159cd 92 Gene3D G3DSA:2.40.50.100 21 91 5.4E-32 T 14-10-2018 TSH58p_13750 4a780046b0e055e2502e87f34ae159cd 92 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 78 2.0E-15 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_13750 4a780046b0e055e2502e87f34ae159cd 92 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 14-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_13750 4a780046b0e055e2502e87f34ae159cd 92 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 81 1.1E-39 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_13750 4a780046b0e055e2502e87f34ae159cd 92 Pfam PF01016 Ribosomal L27 protein 2 81 5.8E-39 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_13750 4a780046b0e055e2502e87f34ae159cd 92 PRINTS PR00063 Ribosomal protein L27 signature 4 28 5.4E-37 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_13750 4a780046b0e055e2502e87f34ae159cd 92 PRINTS PR00063 Ribosomal protein L27 signature 29 53 5.4E-37 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_13750 4a780046b0e055e2502e87f34ae159cd 92 PRINTS PR00063 Ribosomal protein L27 signature 54 78 5.4E-37 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_13750 4a780046b0e055e2502e87f34ae159cd 92 SUPERFAMILY SSF110324 2 81 1.12E-34 T 14-10-2018 TSH58p_03875 40660d9bcf5ff4d857ead322f6172db9 274 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 144 264 3.9E-22 T 14-10-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 TSH58p_03875 40660d9bcf5ff4d857ead322f6172db9 274 SUPERFAMILY SSF47188 141 264 1.83E-22 T 14-10-2018 IPR035938 Hemerythrin-like superfamily TSH58p_03875 40660d9bcf5ff4d857ead322f6172db9 274 Gene3D G3DSA:1.20.120.50 138 269 1.4E-21 T 14-10-2018 IPR035938 Hemerythrin-like superfamily TSH58p_03875 40660d9bcf5ff4d857ead322f6172db9 274 Gene3D G3DSA:1.20.120.50 7 135 1.3E-11 T 14-10-2018 IPR035938 Hemerythrin-like superfamily TSH58p_03875 40660d9bcf5ff4d857ead322f6172db9 274 SUPERFAMILY SSF47188 10 127 2.35E-13 T 14-10-2018 IPR035938 Hemerythrin-like superfamily TSH58p_03875 40660d9bcf5ff4d857ead322f6172db9 274 Pfam PF01814 Hemerythrin HHE cation binding domain 156 256 8.3E-8 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 TSH58p_13075 c0d8a103f575a5e846cde2cdbfcc6937 371 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 15 350 30.642 T 14-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 TSH58p_13075 c0d8a103f575a5e846cde2cdbfcc6937 371 Gene3D G3DSA:3.40.1390.10 5 105 6.9E-9 T 14-10-2018 TSH58p_13075 c0d8a103f575a5e846cde2cdbfcc6937 371 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 292 320 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 TSH58p_13075 c0d8a103f575a5e846cde2cdbfcc6937 371 Gene3D G3DSA:2.160.10.10 108 334 4.1E-62 T 14-10-2018 TSH58p_13075 c0d8a103f575a5e846cde2cdbfcc6937 371 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 154 188 4.0E-8 T 14-10-2018 IPR001451 Hexapeptide repeat TSH58p_13075 c0d8a103f575a5e846cde2cdbfcc6937 371 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 283 317 2.7E-5 T 14-10-2018 IPR001451 Hexapeptide repeat TSH58p_13075 c0d8a103f575a5e846cde2cdbfcc6937 371 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 118 151 5.9E-6 T 14-10-2018 IPR001451 Hexapeptide repeat TSH58p_13075 c0d8a103f575a5e846cde2cdbfcc6937 371 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 248 282 5.0E-8 T 14-10-2018 IPR001451 Hexapeptide repeat TSH58p_13075 c0d8a103f575a5e846cde2cdbfcc6937 371 SUPERFAMILY SSF51161 65 339 8.95E-71 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily TSH58p_13075 c0d8a103f575a5e846cde2cdbfcc6937 371 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 14 349 6.8E-85 T 14-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 TSH58p_13075 c0d8a103f575a5e846cde2cdbfcc6937 371 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 211 241 0.018 T 14-10-2018 IPR001451 Hexapeptide repeat TSH58p_12160 6bc1d930907950b1740843735056d596 302 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 6 122 6.8E-38 T 14-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TSH58p_12160 6bc1d930907950b1740843735056d596 302 Hamap MF_01576 Bifunctional protein FolD [folD]. 4 292 38.304 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TSH58p_12160 6bc1d930907950b1740843735056d596 302 Gene3D G3DSA:3.40.50.10860 9 285 8.0E-104 T 14-10-2018 TSH58p_12160 6bc1d930907950b1740843735056d596 302 SUPERFAMILY SSF53223 4 123 2.4E-39 T 14-10-2018 TSH58p_12160 6bc1d930907950b1740843735056d596 302 SUPERFAMILY SSF51735 124 289 1.49E-50 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_12160 6bc1d930907950b1740843735056d596 302 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 269 277 - T 14-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TSH58p_12160 6bc1d930907950b1740843735056d596 302 Gene3D G3DSA:3.40.50.720 7 268 8.0E-104 T 14-10-2018 TSH58p_12160 6bc1d930907950b1740843735056d596 302 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 125 290 1.2E-64 T 14-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TSH58p_12160 6bc1d930907950b1740843735056d596 302 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 77 102 - T 14-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TSH58p_12160 6bc1d930907950b1740843735056d596 302 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 207 236 2.8E-81 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TSH58p_12160 6bc1d930907950b1740843735056d596 302 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 35 57 2.8E-81 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TSH58p_12160 6bc1d930907950b1740843735056d596 302 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 265 283 2.8E-81 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TSH58p_12160 6bc1d930907950b1740843735056d596 302 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 111 132 2.8E-81 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TSH58p_12160 6bc1d930907950b1740843735056d596 302 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 248 264 2.8E-81 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TSH58p_12160 6bc1d930907950b1740843735056d596 302 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 158 178 2.8E-81 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TSH58p_12160 6bc1d930907950b1740843735056d596 302 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 76 103 2.8E-81 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TSH58p_16215 80e899799f0f560571bb46071602bebd 212 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 6 208 23.071 T 14-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSH58p_16215 80e899799f0f560571bb46071602bebd 212 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 7 198 2.9E-54 T 14-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSH58p_16215 80e899799f0f560571bb46071602bebd 212 Gene3D G3DSA:3.20.20.70 1 211 4.3E-66 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_16215 80e899799f0f560571bb46071602bebd 212 SUPERFAMILY SSF51391 5 201 1.7E-64 T 14-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSH58p_16215 80e899799f0f560571bb46071602bebd 212 Pfam PF02581 Thiamine monophosphate synthase 8 189 3.9E-56 T 14-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSH58p_11855 077b2ede181be340d96834c0e24d2486 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.3E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_11855 077b2ede181be340d96834c0e24d2486 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.3E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_11855 077b2ede181be340d96834c0e24d2486 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.3E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_11855 077b2ede181be340d96834c0e24d2486 307 SUPERFAMILY SSF53850 89 282 1.47E-38 T 14-10-2018 TSH58p_11855 077b2ede181be340d96834c0e24d2486 307 Gene3D G3DSA:1.10.10.10 1 88 4.9E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_11855 077b2ede181be340d96834c0e24d2486 307 Gene3D G3DSA:3.40.190.290 90 288 8.5E-36 T 14-10-2018 TSH58p_11855 077b2ede181be340d96834c0e24d2486 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 3.2E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_11855 077b2ede181be340d96834c0e24d2486 307 Pfam PF03466 LysR substrate binding domain 86 282 2.6E-42 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_11855 077b2ede181be340d96834c0e24d2486 307 SUPERFAMILY SSF46785 1 110 5.1E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_21540 d181f34ec1c717e61c98e32cef23e6c6 419 Pfam PF16360 GTP-binding GTPase Middle Region 108 187 3.5E-30 T 14-10-2018 IPR032305 GTP-binding protein, middle domain TSH58p_21540 d181f34ec1c717e61c98e32cef23e6c6 419 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 19 359 4.6E-136 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 TSH58p_21540 d181f34ec1c717e61c98e32cef23e6c6 419 Hamap MF_00900 GTPase HflX [hflX]. 21 389 46.584 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 TSH58p_21540 d181f34ec1c717e61c98e32cef23e6c6 419 Pfam PF01926 50S ribosome-binding GTPase 195 316 1.9E-19 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 TSH58p_21540 d181f34ec1c717e61c98e32cef23e6c6 419 Gene3D G3DSA:3.40.50.11060 13 132 5.7E-35 T 14-10-2018 TSH58p_21540 d181f34ec1c717e61c98e32cef23e6c6 419 SUPERFAMILY SSF52540 193 368 6.28E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_21540 d181f34ec1c717e61c98e32cef23e6c6 419 Gene3D G3DSA:3.40.50.300 192 366 3.6E-39 T 14-10-2018 TSH58p_21540 d181f34ec1c717e61c98e32cef23e6c6 419 Pfam PF13167 GTP-binding GTPase N-terminal 20 105 3.5E-27 T 14-10-2018 IPR025121 GTPase HflX, N-terminal TSH58p_21540 d181f34ec1c717e61c98e32cef23e6c6 419 PIRSF PIRSF006809 2 418 2.5E-144 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 TSH58p_21540 d181f34ec1c717e61c98e32cef23e6c6 419 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 262 280 1.2E-6 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 TSH58p_21540 d181f34ec1c717e61c98e32cef23e6c6 419 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 195 215 1.2E-6 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 TSH58p_18370 5e0c64c4a4a553a648c86e3b7250036a 365 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 336 1.7E-142 T 14-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 TSH58p_18370 5e0c64c4a4a553a648c86e3b7250036a 365 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 323 4.2E-89 T 14-10-2018 IPR016040 NAD(P)-binding domain TSH58p_18370 5e0c64c4a4a553a648c86e3b7250036a 365 Gene3D G3DSA:3.90.25.10 200 330 1.5E-124 T 14-10-2018 TSH58p_18370 5e0c64c4a4a553a648c86e3b7250036a 365 Gene3D G3DSA:3.40.50.720 2 322 1.5E-124 T 14-10-2018 TSH58p_18370 5e0c64c4a4a553a648c86e3b7250036a 365 SUPERFAMILY SSF51735 1 335 5.37E-89 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_17965 53605944c388ec49292ac2618eeaf2db 197 Pfam PF06055 Exopolysaccharide synthesis, ExoD 8 179 3.0E-39 T 14-10-2018 IPR010331 Exopolysaccharide synthesis, ExoD TSH58p_17965 53605944c388ec49292ac2618eeaf2db 197 PIRSF PIRSF033239 1 194 1.6E-39 T 14-10-2018 IPR010331 Exopolysaccharide synthesis, ExoD TSH58p_24545 79b9cd972db6b37154ac209f1585999d 299 Gene3D G3DSA:3.40.190.10 165 266 1.8E-65 T 14-10-2018 TSH58p_24545 79b9cd972db6b37154ac209f1585999d 299 SUPERFAMILY SSF46785 8 114 1.26E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_24545 79b9cd972db6b37154ac209f1585999d 299 Pfam PF03466 LysR substrate binding domain 90 293 1.2E-41 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_24545 79b9cd972db6b37154ac209f1585999d 299 Gene3D G3DSA:3.40.190.10 94 290 1.8E-65 T 14-10-2018 TSH58p_24545 79b9cd972db6b37154ac209f1585999d 299 SUPERFAMILY SSF53850 92 296 1.76E-43 T 14-10-2018 TSH58p_24545 79b9cd972db6b37154ac209f1585999d 299 Gene3D G3DSA:1.10.10.10 5 91 2.2E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_24545 79b9cd972db6b37154ac209f1585999d 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 1.4E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_25370 aebf05a453675bd68a857bd418397ae9 462 Pfam PF07690 Major Facilitator Superfamily 63 374 5.8E-27 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_25370 aebf05a453675bd68a857bd418397ae9 462 SUPERFAMILY SSF103473 20 446 1.83E-58 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_25370 aebf05a453675bd68a857bd418397ae9 462 ProSitePatterns PS00217 Sugar transport proteins signature 2. 140 165 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TSH58p_25370 aebf05a453675bd68a857bd418397ae9 462 ProSitePatterns PS00216 Sugar transport proteins signature 1. 310 327 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TSH58p_25370 aebf05a453675bd68a857bd418397ae9 462 Gene3D G3DSA:1.20.1250.20 27 454 5.2E-58 T 14-10-2018 TSH58p_19710 a1f3165f872123d679ff0a8219ec8d74 998 Gene3D G3DSA:2.20.25.90 52 113 1.0E-15 T 14-10-2018 TSH58p_19710 a1f3165f872123d679ff0a8219ec8d74 998 Gene3D G3DSA:3.40.228.10 194 297 1.9E-39 T 14-10-2018 TSH58p_19710 a1f3165f872123d679ff0a8219ec8d74 998 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 57 108 7.0E-15 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_19710 a1f3165f872123d679ff0a8219ec8d74 998 Gene3D G3DSA:3.40.228.10 358 465 1.0E-12 T 14-10-2018 TSH58p_19710 a1f3165f872123d679ff0a8219ec8d74 998 Pfam PF01568 Molydopterin dinucleotide binding domain 819 906 6.6E-12 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TSH58p_19710 a1f3165f872123d679ff0a8219ec8d74 998 SMART SM00926 55 109 2.0E-19 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_19710 a1f3165f872123d679ff0a8219ec8d74 998 SUPERFAMILY SSF53706 49 775 9.29E-136 T 14-10-2018 TSH58p_19710 a1f3165f872123d679ff0a8219ec8d74 998 SUPERFAMILY SSF50692 812 965 4.52E-32 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TSH58p_19710 a1f3165f872123d679ff0a8219ec8d74 998 Pfam PF00384 Molybdopterin oxidoreductase 113 397 1.9E-22 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_19710 a1f3165f872123d679ff0a8219ec8d74 998 Gene3D G3DSA:2.40.40.20 794 960 2.5E-24 T 14-10-2018 TSH58p_19710 a1f3165f872123d679ff0a8219ec8d74 998 Gene3D G3DSA:3.40.50.740 518 674 8.9E-15 T 14-10-2018 TSH58p_19710 a1f3165f872123d679ff0a8219ec8d74 998 Gene3D G3DSA:3.40.50.740 114 193 1.9E-39 T 14-10-2018 TSH58p_30275 19c67374403e4760525695c5a72d9f7d 558 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_30275 19c67374403e4760525695c5a72d9f7d 558 SMART SM00382 358 544 9.6E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_30275 19c67374403e4760525695c5a72d9f7d 558 SUPERFAMILY SSF90123 3 321 2.88E-73 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_30275 19c67374403e4760525695c5a72d9f7d 558 Gene3D G3DSA:3.40.50.300 329 558 1.4E-84 T 14-10-2018 TSH58p_30275 19c67374403e4760525695c5a72d9f7d 558 Gene3D G3DSA:1.20.1560.10 1 315 2.3E-74 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_30275 19c67374403e4760525695c5a72d9f7d 558 SUPERFAMILY SSF52540 322 557 8.77E-85 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_30275 19c67374403e4760525695c5a72d9f7d 558 Pfam PF00664 ABC transporter transmembrane region 17 286 6.1E-49 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TSH58p_30275 19c67374403e4760525695c5a72d9f7d 558 Pfam PF00005 ABC transporter 349 498 1.3E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_06310 7af063bf2d11989ecd60da88dfdc32d9 126 Gene3D G3DSA:1.10.10.10 10 125 6.4E-43 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_06310 7af063bf2d11989ecd60da88dfdc32d9 126 SUPERFAMILY SSF46785 13 111 3.99E-36 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_06310 7af063bf2d11989ecd60da88dfdc32d9 126 Pfam PF01638 HxlR-like helix-turn-helix 23 111 5.8E-37 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type TSH58p_22575 238dbf14b76dc1149d08cb321fa641e5 168 Pfam PF10688 Bacterial inner membrane protein 4 163 7.2E-26 T 14-10-2018 IPR019629 Uncharacterised protein family HI1736/YgjV TSH58p_06285 112559759c16190135c52f9447c44b7a 330 Gene3D G3DSA:3.40.50.1100 14 320 3.0E-106 T 14-10-2018 TSH58p_06285 112559759c16190135c52f9447c44b7a 330 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 49 62 - T 14-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 TSH58p_06285 112559759c16190135c52f9447c44b7a 330 SUPERFAMILY SSF53686 11 323 3.4E-90 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TSH58p_06285 112559759c16190135c52f9447c44b7a 330 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 25 315 4.2E-74 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TSH58p_06285 112559759c16190135c52f9447c44b7a 330 Gene3D G3DSA:3.40.50.1100 57 153 3.0E-106 T 14-10-2018 TSH58p_16690 dcbfd5b617a80effca80ed29252177ec 1107 Pfam PF00128 Alpha amylase, catalytic domain 39 396 4.4E-75 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSH58p_16690 dcbfd5b617a80effca80ed29252177ec 1107 TIGRFAM TIGR02456 treS_nterm: trehalose synthase 16 559 2.1E-282 T 14-10-2018 IPR012810 Trehalose synthase/alpha-amylase, N-terminal GO:0003824|GO:0005975 KEGG: 00500+5.4.99.16|MetaCyc: PWY-2622|MetaCyc: PWY-7900 TSH58p_16690 dcbfd5b617a80effca80ed29252177ec 1107 Gene3D G3DSA:2.60.40.1180 475 569 3.0E-34 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta TSH58p_16690 dcbfd5b617a80effca80ed29252177ec 1107 Gene3D G3DSA:3.20.20.80 16 470 1.3E-220 T 14-10-2018 TSH58p_16690 dcbfd5b617a80effca80ed29252177ec 1107 SMART SM00642 24 427 8.5E-105 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSH58p_16690 dcbfd5b617a80effca80ed29252177ec 1107 Gene3D G3DSA:3.90.400.10 114 184 1.3E-220 T 14-10-2018 TSH58p_16690 dcbfd5b617a80effca80ed29252177ec 1107 Gene3D G3DSA:3.90.1200.10 819 1107 2.2E-66 T 14-10-2018 TSH58p_16690 dcbfd5b617a80effca80ed29252177ec 1107 Pfam PF16657 Maltogenic Amylase, C-terminal domain 475 556 7.9E-27 T 14-10-2018 IPR032091 Maltogenic Amylase, C-terminal TSH58p_16690 dcbfd5b617a80effca80ed29252177ec 1107 SUPERFAMILY SSF56112 738 1077 2.04E-15 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily TSH58p_16690 dcbfd5b617a80effca80ed29252177ec 1107 Pfam PF01636 Phosphotransferase enzyme family 860 1005 1.1E-5 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase TSH58p_16690 dcbfd5b617a80effca80ed29252177ec 1107 TIGRFAM TIGR02457 TreS_Cterm: putative maltokinase 576 1102 7.3E-159 T 14-10-2018 IPR012811 Trehalose synthase/probable maltokinase, C-terminal domain TSH58p_16690 dcbfd5b617a80effca80ed29252177ec 1107 SUPERFAMILY SSF51445 15 472 1.97E-128 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_16690 dcbfd5b617a80effca80ed29252177ec 1107 SUPERFAMILY SSF51011 479 559 5.2E-16 T 14-10-2018 TSH58p_10085 8cddbf29ed00017e977399b8a8a06a9a 316 SMART SM00062 28 248 3.0E-6 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_10085 8cddbf29ed00017e977399b8a8a06a9a 316 Gene3D G3DSA:3.40.190.10 21 134 2.7E-13 T 14-10-2018 TSH58p_10085 8cddbf29ed00017e977399b8a8a06a9a 316 SUPERFAMILY SSF53850 26 243 1.43E-42 T 14-10-2018 TSH58p_10085 8cddbf29ed00017e977399b8a8a06a9a 316 Pfam PF09084 NMT1/THI5 like 36 240 3.8E-25 T 14-10-2018 IPR015168 SsuA/THI5-like TSH58p_10085 8cddbf29ed00017e977399b8a8a06a9a 316 Gene3D G3DSA:3.40.190.10 135 316 4.6E-35 T 14-10-2018 TSH58p_05750 283e688dc37d483069ee3bb744388f98 245 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 13 239 7.2E-87 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TSH58p_05750 283e688dc37d483069ee3bb744388f98 245 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 185 202 - T 14-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 TSH58p_05750 283e688dc37d483069ee3bb744388f98 245 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 12 240 41.644 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TSH58p_05750 283e688dc37d483069ee3bb744388f98 245 Gene3D G3DSA:3.40.1180.10 3 241 1.7E-96 T 14-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 TSH58p_05750 283e688dc37d483069ee3bb744388f98 245 SUPERFAMILY SSF64005 12 234 2.22E-86 T 14-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 TSH58p_05750 283e688dc37d483069ee3bb744388f98 245 Pfam PF01255 Putative undecaprenyl diphosphate synthase 19 239 2.8E-82 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TSH58p_24105 26aed079f901760dbb366492fd892994 182 SUPERFAMILY SSF48498 71 174 5.34E-11 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TSH58p_24105 26aed079f901760dbb366492fd892994 182 Pfam PF00440 Bacterial regulatory proteins, tetR family 5 49 9.4E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_24105 26aed079f901760dbb366492fd892994 182 Gene3D G3DSA:1.10.357.10 59 178 1.2E-11 T 14-10-2018 TSH58p_24105 26aed079f901760dbb366492fd892994 182 Gene3D G3DSA:1.10.10.60 1 58 3.7E-20 T 14-10-2018 TSH58p_24105 26aed079f901760dbb366492fd892994 182 SUPERFAMILY SSF46689 3 71 9.23E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_07505 9773f52338ff538c4ba88682f79f1a0e 321 SUPERFAMILY SSF53335 84 319 4.45E-23 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_07505 9773f52338ff538c4ba88682f79f1a0e 321 Pfam PF02353 Mycolic acid cyclopropane synthetase 98 209 1.5E-7 T 14-10-2018 TSH58p_07505 9773f52338ff538c4ba88682f79f1a0e 321 Gene3D G3DSA:3.40.50.150 65 317 4.1E-25 T 14-10-2018 TSH58p_05280 2dfbd0491884d79d4260354adc7e71df 195 SUPERFAMILY SSF103088 75 185 1.57E-28 T 14-10-2018 IPR036737 OmpA-like domain superfamily TSH58p_05280 2dfbd0491884d79d4260354adc7e71df 195 Pfam PF00691 OmpA family 86 181 3.1E-18 T 14-10-2018 IPR006665 OmpA-like domain TSH58p_05280 2dfbd0491884d79d4260354adc7e71df 195 PRINTS PR01021 OMPA domain signature 132 148 4.0E-14 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 TSH58p_05280 2dfbd0491884d79d4260354adc7e71df 195 PRINTS PR01021 OMPA domain signature 117 132 4.0E-14 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 TSH58p_05280 2dfbd0491884d79d4260354adc7e71df 195 PRINTS PR01021 OMPA domain signature 87 109 4.0E-14 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 TSH58p_05280 2dfbd0491884d79d4260354adc7e71df 195 Gene3D G3DSA:3.30.1330.60 68 186 4.4E-30 T 14-10-2018 IPR036737 OmpA-like domain superfamily TSH58p_20910 6fdb67379dc340e696eaf83092a52dea 412 Pfam PF07690 Major Facilitator Superfamily 34 373 9.0E-26 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_20910 6fdb67379dc340e696eaf83092a52dea 412 Gene3D G3DSA:1.20.1250.20 26 201 1.2E-15 T 14-10-2018 TSH58p_20910 6fdb67379dc340e696eaf83092a52dea 412 SUPERFAMILY SSF103473 17 410 6.02E-46 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_20910 6fdb67379dc340e696eaf83092a52dea 412 Gene3D G3DSA:1.20.1250.20 221 412 1.3E-19 T 14-10-2018 TSH58p_00915 1e8d636022e690567e4a600e43d593fa 189 SUPERFAMILY SSF55729 14 152 2.52E-17 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_00915 1e8d636022e690567e4a600e43d593fa 189 Gene3D G3DSA:3.40.630.30 12 164 1.1E-14 T 14-10-2018 TSH58p_00915 1e8d636022e690567e4a600e43d593fa 189 Pfam PF13673 Acetyltransferase (GNAT) domain 43 151 1.5E-9 T 14-10-2018 IPR000182 GNAT domain TSH58p_28190 2f64df0764a89bf1032c5b84bddd21fd 110 Pfam PF14279 HNH endonuclease 19 66 3.2E-9 T 14-10-2018 IPR029471 HNH endonuclease 5 TSH58p_28190 2f64df0764a89bf1032c5b84bddd21fd 110 SMART SM00507 7 58 1.2E-4 T 14-10-2018 IPR003615 HNH nuclease TSH58p_28190 2f64df0764a89bf1032c5b84bddd21fd 110 Gene3D G3DSA:3.30.40.60 5 83 5.2E-16 T 14-10-2018 TSH58p_01450 ebdb7ca161d4ff379b6c0c20fadb5407 316 Gene3D G3DSA:2.60.120.1440 107 222 1.3E-14 T 14-10-2018 TSH58p_01450 ebdb7ca161d4ff379b6c0c20fadb5407 316 PIRSF PIRSF018266 6 315 1.7E-75 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component TSH58p_01450 ebdb7ca161d4ff379b6c0c20fadb5407 316 Pfam PF16220 Domain of unknown function (DUF4880) 17 57 1.2E-14 T 14-10-2018 IPR032623 FecR, N-terminal TSH58p_01450 ebdb7ca161d4ff379b6c0c20fadb5407 316 Pfam PF04773 FecR protein 110 201 2.1E-16 T 14-10-2018 IPR006860 FecR protein TSH58p_11665 c830eb823641f2ba12b1da7d8963c0e1 756 Pfam PF03949 Malic enzyme, NAD binding domain 170 364 4.0E-24 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 TSH58p_11665 c830eb823641f2ba12b1da7d8963c0e1 756 Pfam PF00390 Malic enzyme, N-terminal domain 24 119 4.6E-21 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 TSH58p_11665 c830eb823641f2ba12b1da7d8963c0e1 756 PIRSF PIRSF036684 3 755 0.0 T 14-10-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 TSH58p_11665 c830eb823641f2ba12b1da7d8963c0e1 756 SMART SM00919 168 405 7.5E-144 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 TSH58p_11665 c830eb823641f2ba12b1da7d8963c0e1 756 SMART SM01274 23 156 1.6E-79 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 TSH58p_11665 c830eb823641f2ba12b1da7d8963c0e1 756 Gene3D G3DSA:3.40.50.10750 574 726 2.0E-85 T 14-10-2018 TSH58p_11665 c830eb823641f2ba12b1da7d8963c0e1 756 Gene3D G3DSA:3.40.50.720 166 450 1.3E-86 T 14-10-2018 TSH58p_11665 c830eb823641f2ba12b1da7d8963c0e1 756 ProSitePatterns PS00331 Malic enzymes signature. 164 180 - T 14-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 TSH58p_11665 c830eb823641f2ba12b1da7d8963c0e1 756 SUPERFAMILY SSF51735 168 457 2.37E-87 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_11665 c830eb823641f2ba12b1da7d8963c0e1 756 SUPERFAMILY SSF53223 14 166 2.52E-53 T 14-10-2018 TSH58p_11665 c830eb823641f2ba12b1da7d8963c0e1 756 Gene3D G3DSA:3.40.50.10950 451 750 2.0E-85 T 14-10-2018 TSH58p_11665 c830eb823641f2ba12b1da7d8963c0e1 756 Pfam PF01515 Phosphate acetyl/butaryl transferase 436 750 5.3E-82 T 14-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 TSH58p_11665 c830eb823641f2ba12b1da7d8963c0e1 756 SUPERFAMILY SSF53659 435 752 1.52E-85 T 14-10-2018 TSH58p_11665 c830eb823641f2ba12b1da7d8963c0e1 756 Gene3D G3DSA:3.40.50.10380 4 165 1.6E-64 T 14-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 TSH58p_06445 372cfb1aa86c20894053649ef559dfdc 324 Pfam PF02653 Branched-chain amino acid transport system / permease component 14 302 3.6E-37 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_04910 bbfb91413e1bae1c0e05fdb0eb9d8179 276 Gene3D G3DSA:3.90.550.10 10 221 8.0E-11 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_04910 bbfb91413e1bae1c0e05fdb0eb9d8179 276 SUPERFAMILY SSF53448 10 214 3.94E-20 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_04500 d7d11a4bf3f788e155e83ca41f634fbf 652 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 410 439 2.1E-17 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_04500 d7d11a4bf3f788e155e83ca41f634fbf 652 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 520 549 2.1E-17 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_04500 d7d11a4bf3f788e155e83ca41f634fbf 652 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 491 518 2.1E-17 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_04500 d7d11a4bf3f788e155e83ca41f634fbf 652 SMART SM01358 40 274 3.5E-7 T 14-10-2018 IPR032255 Helical bimodular sensor domain TSH58p_04500 d7d11a4bf3f788e155e83ca41f634fbf 652 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 470 622 4.9E-31 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_04500 d7d11a4bf3f788e155e83ca41f634fbf 652 SMART SM00304 303 356 3.2E-11 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_04500 d7d11a4bf3f788e155e83ca41f634fbf 652 SUPERFAMILY SSF58104 330 646 8.89E-57 T 14-10-2018 TSH58p_04500 d7d11a4bf3f788e155e83ca41f634fbf 652 Pfam PF00672 HAMP domain 303 353 9.3E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_04500 d7d11a4bf3f788e155e83ca41f634fbf 652 SMART SM00283 393 647 3.5E-40 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_04500 d7d11a4bf3f788e155e83ca41f634fbf 652 Gene3D G3DSA:1.10.8.500 303 351 5.8E-18 T 14-10-2018 TSH58p_04500 d7d11a4bf3f788e155e83ca41f634fbf 652 Gene3D G3DSA:1.10.287.950 352 652 1.2E-50 T 14-10-2018 TSH58p_01940 12ece9b57c64be740164f4a40c7255b8 477 Pfam PF04932 O-Antigen ligase 243 385 3.0E-14 T 14-10-2018 IPR007016 O-antigen ligase-related TSH58p_02760 58428b2d7376e209de35dec6feac5621 290 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 15 61 1.4E-10 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TSH58p_02760 58428b2d7376e209de35dec6feac5621 290 Gene3D G3DSA:1.10.3720.10 76 286 2.0E-23 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_02760 58428b2d7376e209de35dec6feac5621 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 285 1.6E-27 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_02760 58428b2d7376e209de35dec6feac5621 290 SUPERFAMILY SSF161098 80 266 6.41E-31 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_21865 8e5c5fd5437777af4dc3ac1701241c1b 543 Gene3D G3DSA:3.30.565.10 382 543 2.5E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_21865 8e5c5fd5437777af4dc3ac1701241c1b 543 SMART SM00387 421 542 9.3E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_21865 8e5c5fd5437777af4dc3ac1701241c1b 543 SUPERFAMILY SSF47384 293 364 1.59E-5 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_21865 8e5c5fd5437777af4dc3ac1701241c1b 543 SUPERFAMILY SSF55874 382 540 8.91E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_21865 8e5c5fd5437777af4dc3ac1701241c1b 543 Gene3D G3DSA:1.10.287.130 253 366 2.6E-7 T 14-10-2018 TSH58p_21865 8e5c5fd5437777af4dc3ac1701241c1b 543 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 423 540 1.1E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_28795 10a2b998ce7086edddf3a0d42ab993ba 303 Pfam PF01817 Chorismate mutase type II 12 100 7.8E-17 T 14-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TSH58p_28795 10a2b998ce7086edddf3a0d42ab993ba 303 Gene3D G3DSA:1.20.59.10 5 102 9.7E-17 T 14-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TSH58p_28795 10a2b998ce7086edddf3a0d42ab993ba 303 SUPERFAMILY SSF48600 6 101 3.36E-13 T 14-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TSH58p_28795 10a2b998ce7086edddf3a0d42ab993ba 303 SMART SM00830 12 103 1.9E-19 T 14-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TSH58p_18220 201e9baa9e3c8c3c48df50a56c2a749a 368 SUPERFAMILY SSF48452 2 172 1.45E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_18220 201e9baa9e3c8c3c48df50a56c2a749a 368 SUPERFAMILY SSF48452 115 342 1.77E-22 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_18220 201e9baa9e3c8c3c48df50a56c2a749a 368 Gene3D G3DSA:1.25.40.10 1 79 1.7E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_18220 201e9baa9e3c8c3c48df50a56c2a749a 368 Pfam PF13432 Tetratricopeptide repeat 2 46 4.3E-6 T 14-10-2018 TSH58p_18220 201e9baa9e3c8c3c48df50a56c2a749a 368 Pfam PF13432 Tetratricopeptide repeat 244 305 3.8E-4 T 14-10-2018 TSH58p_18220 201e9baa9e3c8c3c48df50a56c2a749a 368 SMART SM00028 29 61 340.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_18220 201e9baa9e3c8c3c48df50a56c2a749a 368 SMART SM00028 273 306 9.2 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_18220 201e9baa9e3c8c3c48df50a56c2a749a 368 SMART SM00028 139 172 0.0034 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_18220 201e9baa9e3c8c3c48df50a56c2a749a 368 SMART SM00028 1 28 30.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_18220 201e9baa9e3c8c3c48df50a56c2a749a 368 SMART SM00028 239 272 0.66 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_18220 201e9baa9e3c8c3c48df50a56c2a749a 368 Gene3D G3DSA:1.25.40.10 80 368 2.1E-34 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_02855 94b76180fd9577d5dd442370e85521ce 359 SUPERFAMILY SSF51735 5 334 7.38E-85 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_02855 94b76180fd9577d5dd442370e85521ce 359 Gene3D G3DSA:3.40.50.720 4 340 3.8E-98 T 14-10-2018 TSH58p_02855 94b76180fd9577d5dd442370e85521ce 359 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 329 2.1E-55 T 14-10-2018 IPR016040 NAD(P)-binding domain TSH58p_22520 a657e95e0b846b83292a211f0389ff05 261 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 2 253 1.1E-68 T 14-10-2018 TSH58p_22520 a657e95e0b846b83292a211f0389ff05 261 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 247 3.3E-21 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase TSH58p_22520 a657e95e0b846b83292a211f0389ff05 261 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 254 6.4E-70 T 14-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 TSH58p_22520 a657e95e0b846b83292a211f0389ff05 261 SUPERFAMILY SSF56219 2 255 4.71E-80 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TSH58p_22520 a657e95e0b846b83292a211f0389ff05 261 Gene3D G3DSA:3.60.10.10 1 255 5.3E-72 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TSH58p_07420 72b24598716c869038f616eec372a0e7 160 Pfam PF00578 AhpC/TSA family 12 139 5.4E-39 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TSH58p_07420 72b24598716c869038f616eec372a0e7 160 SUPERFAMILY SSF52833 9 160 9.57E-54 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_07420 72b24598716c869038f616eec372a0e7 160 PIRSF PIRSF000239 4 160 3.3E-26 T 14-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TSH58p_07420 72b24598716c869038f616eec372a0e7 160 Gene3D G3DSA:3.40.30.10 7 159 4.7E-51 T 14-10-2018 TSH58p_13095 b464ed21cfd030e4e149fe65453a4f88 342 Gene3D G3DSA:3.40.50.10210 66 320 1.0E-106 T 14-10-2018 TSH58p_13095 b464ed21cfd030e4e149fe65453a4f88 342 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 25 337 2.6E-119 T 14-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 TSH58p_13095 b464ed21cfd030e4e149fe65453a4f88 342 SUPERFAMILY SSF52733 15 338 5.89E-112 T 14-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 TSH58p_13095 b464ed21cfd030e4e149fe65453a4f88 342 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 22 339 34.414 T 14-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 TSH58p_13095 b464ed21cfd030e4e149fe65453a4f88 342 Pfam PF02277 Phosphoribosyltransferase 22 337 8.8E-116 T 14-10-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 TSH58p_13095 b464ed21cfd030e4e149fe65453a4f88 342 Gene3D G3DSA:1.10.1610.10 22 329 1.0E-106 T 14-10-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 TSH58p_17515 221aa3f2fa0dc3ce37b8cfa1cda0c3e0 456 SUPERFAMILY SSF52540 51 335 8.58E-35 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_17515 221aa3f2fa0dc3ce37b8cfa1cda0c3e0 456 Pfam PF04851 Type III restriction enzyme, res subunit 1 152 5.2E-17 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TSH58p_17515 221aa3f2fa0dc3ce37b8cfa1cda0c3e0 456 Pfam PF00271 Helicase conserved C-terminal domain 225 324 6.2E-10 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_17515 221aa3f2fa0dc3ce37b8cfa1cda0c3e0 456 Gene3D G3DSA:3.40.50.300 1 167 2.5E-25 T 14-10-2018 TSH58p_17515 221aa3f2fa0dc3ce37b8cfa1cda0c3e0 456 SMART SM00487 2 178 1.6E-6 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSH58p_17515 221aa3f2fa0dc3ce37b8cfa1cda0c3e0 456 Gene3D G3DSA:3.40.50.300 200 344 1.3E-20 T 14-10-2018 TSH58p_30800 2dd0b2f7dd82787b85cc04fbc73700f3 338 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 64 334 7.7E-69 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 TSH58p_30800 2dd0b2f7dd82787b85cc04fbc73700f3 338 PIRSF PIRSF017082 7 337 9.9E-78 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 TSH58p_30800 2dd0b2f7dd82787b85cc04fbc73700f3 338 Gene3D G3DSA:3.40.190.150 44 328 2.0E-97 T 14-10-2018 TSH58p_30800 2dd0b2f7dd82787b85cc04fbc73700f3 338 Gene3D G3DSA:3.40.190.10 140 263 2.0E-97 T 14-10-2018 TSH58p_30800 2dd0b2f7dd82787b85cc04fbc73700f3 338 SUPERFAMILY SSF53850 115 302 5.07E-7 T 14-10-2018 TSH58p_05840 7488e74f928e980c03c656791293772a 257 Gene3D G3DSA:3.30.420.40 1 88 1.8E-27 T 14-10-2018 TSH58p_05840 7488e74f928e980c03c656791293772a 257 Gene3D G3DSA:3.30.420.40 90 257 1.3E-58 T 14-10-2018 TSH58p_05840 7488e74f928e980c03c656791293772a 257 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 255 35.491 T 14-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 TSH58p_05840 7488e74f928e980c03c656791293772a 257 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 248 2.0E-70 T 14-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 TSH58p_05840 7488e74f928e980c03c656791293772a 257 Pfam PF03309 Type III pantothenate kinase 2 207 7.8E-70 T 14-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 TSH58p_05840 7488e74f928e980c03c656791293772a 257 SUPERFAMILY SSF53067 125 254 1.76E-40 T 14-10-2018 TSH58p_05840 7488e74f928e980c03c656791293772a 257 SUPERFAMILY SSF53067 1 122 1.85E-31 T 14-10-2018 TSH58p_17900 258fe6e2e96bacf7fa13a9bd9c20f667 319 Pfam PF16363 GDP-mannose 4,6 dehydratase 12 309 2.5E-55 T 14-10-2018 IPR016040 NAD(P)-binding domain TSH58p_17900 258fe6e2e96bacf7fa13a9bd9c20f667 319 SUPERFAMILY SSF51735 8 317 1.5E-94 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_17900 258fe6e2e96bacf7fa13a9bd9c20f667 319 Gene3D G3DSA:3.40.50.720 8 317 1.5E-110 T 14-10-2018 TSH58p_25750 e773173f5e2263881e1750238f142fab 427 Gene3D G3DSA:3.40.630.10 23 411 2.8E-101 T 14-10-2018 TSH58p_25750 e773173f5e2263881e1750238f142fab 427 Gene3D G3DSA:3.30.70.360 203 337 2.8E-101 T 14-10-2018 TSH58p_25750 e773173f5e2263881e1750238f142fab 427 SUPERFAMILY SSF53187 7 422 3.71E-70 T 14-10-2018 TSH58p_25750 e773173f5e2263881e1750238f142fab 427 Pfam PF07687 Peptidase dimerisation domain 199 320 1.5E-19 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain TSH58p_25750 e773173f5e2263881e1750238f142fab 427 SUPERFAMILY SSF55031 202 336 4.93E-12 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TSH58p_25750 e773173f5e2263881e1750238f142fab 427 Pfam PF01546 Peptidase family M20/M25/M40 93 418 2.1E-40 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 TSH58p_25750 e773173f5e2263881e1750238f142fab 427 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 21 414 3.1E-87 T 14-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase TSH58p_19170 8a113ea3b7593bd362a544e44a133fcf 697 Gene3D G3DSA:1.10.8.540 508 596 7.0E-23 T 14-10-2018 TSH58p_19170 8a113ea3b7593bd362a544e44a133fcf 697 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 22 697 6.5E-265 T 14-10-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 TSH58p_19170 8a113ea3b7593bd362a544e44a133fcf 697 Pfam PF00771 FHIPEP family 33 689 7.5E-250 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 TSH58p_19170 8a113ea3b7593bd362a544e44a133fcf 697 Gene3D G3DSA:1.10.490.80 600 697 2.8E-14 T 14-10-2018 TSH58p_19170 8a113ea3b7593bd362a544e44a133fcf 697 PIRSF PIRSF005419 8 697 6.8E-228 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 TSH58p_19170 8a113ea3b7593bd362a544e44a133fcf 697 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 77 96 1.1E-50 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 TSH58p_19170 8a113ea3b7593bd362a544e44a133fcf 697 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 144 160 1.1E-50 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 TSH58p_19170 8a113ea3b7593bd362a544e44a133fcf 697 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 163 181 1.1E-50 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 TSH58p_19170 8a113ea3b7593bd362a544e44a133fcf 697 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 193 210 1.1E-50 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 TSH58p_19170 8a113ea3b7593bd362a544e44a133fcf 697 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 40 53 1.1E-50 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 TSH58p_19170 8a113ea3b7593bd362a544e44a133fcf 697 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 244 258 1.1E-50 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 TSH58p_19170 8a113ea3b7593bd362a544e44a133fcf 697 Gene3D G3DSA:3.40.30.60 364 507 1.7E-43 T 14-10-2018 TSH58p_23910 7746ba0314a5dc8aa946cd4cd4c41c9e 422 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 275 376 1.6E-42 T 14-10-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 TSH58p_23910 7746ba0314a5dc8aa946cd4cd4c41c9e 422 Pfam PF00033 Cytochrome b/b6/petB 33 218 5.2E-76 T 14-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 TSH58p_23910 7746ba0314a5dc8aa946cd4cd4c41c9e 422 SUPERFAMILY SSF81648 278 394 1.81E-41 T 14-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 TSH58p_23910 7746ba0314a5dc8aa946cd4cd4c41c9e 422 SUPERFAMILY SSF81342 15 277 7.06E-107 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 TSH58p_23910 7746ba0314a5dc8aa946cd4cd4c41c9e 422 Gene3D G3DSA:1.20.810.10 3 419 7.2E-162 T 14-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 TSH58p_23910 7746ba0314a5dc8aa946cd4cd4c41c9e 422 PIRSF PIRSF038885 6 405 1.5E-192 T 14-10-2018 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 TSH58p_14395 c7281fc653b8ff2250c53ac6a39a2ad8 245 Gene3D G3DSA:1.10.287.110 163 244 3.9E-12 T 14-10-2018 IPR036869 Chaperone J-domain superfamily TSH58p_14395 c7281fc653b8ff2250c53ac6a39a2ad8 245 Pfam PF00226 DnaJ domain 179 242 1.5E-9 T 14-10-2018 IPR001623 DnaJ domain TSH58p_14395 c7281fc653b8ff2250c53ac6a39a2ad8 245 SUPERFAMILY SSF46565 174 244 1.64E-15 T 14-10-2018 IPR036869 Chaperone J-domain superfamily TSH58p_14395 c7281fc653b8ff2250c53ac6a39a2ad8 245 PRINTS PR00625 DnaJ domain signature 181 199 9.2E-5 T 14-10-2018 IPR001623 DnaJ domain TSH58p_14395 c7281fc653b8ff2250c53ac6a39a2ad8 245 PRINTS PR00625 DnaJ domain signature 199 214 9.2E-5 T 14-10-2018 IPR001623 DnaJ domain TSH58p_14395 c7281fc653b8ff2250c53ac6a39a2ad8 245 Pfam PF05099 Tellurite resistance protein TerB 43 165 5.8E-32 T 14-10-2018 IPR007791 Co-chaperone DjlA, N-terminal TSH58p_14395 c7281fc653b8ff2250c53ac6a39a2ad8 245 SUPERFAMILY SSF158682 12 193 2.35E-24 T 14-10-2018 IPR029024 TerB-like TSH58p_14395 c7281fc653b8ff2250c53ac6a39a2ad8 245 Gene3D G3DSA:1.10.3680.10 39 162 1.7E-16 T 14-10-2018 IPR029024 TerB-like TSH58p_14395 c7281fc653b8ff2250c53ac6a39a2ad8 245 SMART SM00271 178 243 8.0E-12 T 14-10-2018 IPR001623 DnaJ domain TSH58p_21275 f2255418a19838aeb753a1b053c3cf59 360 Gene3D G3DSA:3.40.710.10 16 355 1.5E-65 T 14-10-2018 TSH58p_21275 f2255418a19838aeb753a1b053c3cf59 360 SUPERFAMILY SSF56601 16 327 2.82E-57 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TSH58p_21275 f2255418a19838aeb753a1b053c3cf59 360 Pfam PF00144 Beta-lactamase 30 347 4.4E-49 T 14-10-2018 IPR001466 Beta-lactamase-related TSH58p_23265 94caa11a6bc21176291f47f3d4cc67f8 263 Pfam PF03459 TOBE domain 197 259 4.2E-16 T 14-10-2018 IPR005116 Transport-associated OB, type 1 TSH58p_23265 94caa11a6bc21176291f47f3d4cc67f8 263 Pfam PF03459 TOBE domain 125 188 3.0E-17 T 14-10-2018 IPR005116 Transport-associated OB, type 1 TSH58p_23265 94caa11a6bc21176291f47f3d4cc67f8 263 PIRSF PIRSF005763 1 263 1.1E-94 T 14-10-2018 IPR016462 Molybdate-dependent transcriptional regulator ModE GO:0006355|GO:0015689|GO:0030151 TSH58p_23265 94caa11a6bc21176291f47f3d4cc67f8 263 Gene3D G3DSA:2.40.50.100 193 263 2.2E-22 T 14-10-2018 TSH58p_23265 94caa11a6bc21176291f47f3d4cc67f8 263 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 196 262 1.8E-19 T 14-10-2018 IPR004606 Molybdenum-pterin binding GO:0015689 TSH58p_23265 94caa11a6bc21176291f47f3d4cc67f8 263 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 123 190 2.5E-23 T 14-10-2018 IPR004606 Molybdenum-pterin binding GO:0015689 TSH58p_23265 94caa11a6bc21176291f47f3d4cc67f8 263 SUPERFAMILY SSF46785 13 108 1.03E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_23265 94caa11a6bc21176291f47f3d4cc67f8 263 SUPERFAMILY SSF50331 196 263 1.66E-17 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSH58p_23265 94caa11a6bc21176291f47f3d4cc67f8 263 SUPERFAMILY SSF50331 123 191 4.62E-21 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSH58p_23265 94caa11a6bc21176291f47f3d4cc67f8 263 Gene3D G3DSA:1.10.10.10 1 110 1.3E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_23265 94caa11a6bc21176291f47f3d4cc67f8 263 Gene3D G3DSA:2.40.50.100 123 189 5.8E-26 T 14-10-2018 TSH58p_23265 94caa11a6bc21176291f47f3d4cc67f8 263 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 20 82 3.0E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_23265 94caa11a6bc21176291f47f3d4cc67f8 263 TIGRFAM TIGR00637 ModE_repress: ModE molybdate transport repressor domain 17 108 1.6E-31 T 14-10-2018 IPR003725 Molybdenum-binding protein ModE, N-terminal TSH58p_00315 11198f521a6dda2b1385fcfc30929666 437 SUPERFAMILY SSF53756 6 419 3.93E-57 T 14-10-2018 TSH58p_00315 11198f521a6dda2b1385fcfc30929666 437 Pfam PF00534 Glycosyl transferases group 1 233 393 4.0E-21 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 TSH58p_00315 11198f521a6dda2b1385fcfc30929666 437 Pfam PF13439 Glycosyltransferase Family 4 19 221 1.4E-14 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TSH58p_00315 11198f521a6dda2b1385fcfc30929666 437 Gene3D G3DSA:3.40.50.2000 234 403 2.5E-31 T 14-10-2018 TSH58p_18570 ea9eac7f428c81ef082cef6716e66b6e 144 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 3 132 6.5E-47 T 14-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 TSH58p_18570 ea9eac7f428c81ef082cef6716e66b6e 144 ProSitePatterns PS01335 Methylglyoxal synthase active site. 58 66 - T 14-10-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 TSH58p_18570 ea9eac7f428c81ef082cef6716e66b6e 144 Gene3D G3DSA:3.40.50.1380 1 144 1.7E-54 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily TSH58p_18570 ea9eac7f428c81ef082cef6716e66b6e 144 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 4 124 30.34 T 14-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 TSH58p_18570 ea9eac7f428c81ef082cef6716e66b6e 144 SUPERFAMILY SSF52335 3 135 6.54E-46 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily TSH58p_18570 ea9eac7f428c81ef082cef6716e66b6e 144 SMART SM00851 17 111 2.5E-12 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain TSH58p_18570 ea9eac7f428c81ef082cef6716e66b6e 144 Pfam PF02142 MGS-like domain 35 110 2.2E-14 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain TSH58p_18570 ea9eac7f428c81ef082cef6716e66b6e 144 PIRSF PIRSF006614 1 143 1.7E-56 T 14-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 TSH58p_19595 95624cc31156381bd00f34ef80873975 369 SUPERFAMILY SSF53335 143 364 1.19E-27 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_19595 95624cc31156381bd00f34ef80873975 369 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 178 323 1.2E-21 T 14-10-2018 IPR006342 Methyltransferase FkbM TSH58p_19595 95624cc31156381bd00f34ef80873975 369 Pfam PF05050 Methyltransferase FkbM domain 180 346 2.1E-15 T 14-10-2018 IPR006342 Methyltransferase FkbM TSH58p_19595 95624cc31156381bd00f34ef80873975 369 Gene3D G3DSA:3.40.50.150 174 334 7.9E-22 T 14-10-2018 TSH58p_22440 b9aca3189ff5ae5f7f5e30903725ca2b 217 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 131 146 - T 14-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 TSH58p_22440 b9aca3189ff5ae5f7f5e30903725ca2b 217 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 7 208 1.1E-57 T 14-10-2018 TSH58p_22440 b9aca3189ff5ae5f7f5e30903725ca2b 217 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 3 212 35.923 T 14-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 TSH58p_22440 b9aca3189ff5ae5f7f5e30903725ca2b 217 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 3 208 2.0E-64 T 14-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 TSH58p_22440 b9aca3189ff5ae5f7f5e30903725ca2b 217 Gene3D G3DSA:3.40.50.150 1 211 1.9E-70 T 14-10-2018 TSH58p_22440 b9aca3189ff5ae5f7f5e30903725ca2b 217 SUPERFAMILY SSF53335 12 207 3.53E-44 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_12260 8a722b142ec4c44f33d4c1214fe85f1a 241 SMART SM00862 158 234 2.2E-26 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_12260 8a722b142ec4c44f33d4c1214fe85f1a 241 SUPERFAMILY SSF46894 139 235 1.87E-26 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_12260 8a722b142ec4c44f33d4c1214fe85f1a 241 SUPERFAMILY SSF52172 3 126 6.12E-45 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_12260 8a722b142ec4c44f33d4c1214fe85f1a 241 Pfam PF00072 Response regulator receiver domain 8 119 1.6E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_12260 8a722b142ec4c44f33d4c1214fe85f1a 241 SMART SM00448 5 118 1.1E-45 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_12260 8a722b142ec4c44f33d4c1214fe85f1a 241 Gene3D G3DSA:1.10.10.10 132 239 2.3E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_12260 8a722b142ec4c44f33d4c1214fe85f1a 241 Gene3D G3DSA:3.40.50.2300 1 127 5.0E-41 T 14-10-2018 TSH58p_12260 8a722b142ec4c44f33d4c1214fe85f1a 241 Pfam PF00486 Transcriptional regulatory protein, C terminal 161 234 8.8E-23 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_32300 6aa80e736a752c08c48732192f4e9c72 433 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 20 426 1.3E-125 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSH58p_32300 6aa80e736a752c08c48732192f4e9c72 433 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 12 420 9.7E-110 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TSH58p_32300 6aa80e736a752c08c48732192f4e9c72 433 PIRSF PIRSF006066 5 432 4.4E-145 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSH58p_00970 e530d7144cbec84eded872b6c1ed601b 1279 SUPERFAMILY SSF51126 47 438 5.65E-13 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor TSH58p_00970 e530d7144cbec84eded872b6c1ed601b 1279 Gene3D G3DSA:2.40.128.130 986 1278 1.4E-53 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily TSH58p_00970 e530d7144cbec84eded872b6c1ed601b 1279 Pfam PF03797 Autotransporter beta-domain 1004 1258 8.0E-54 T 14-10-2018 IPR005546 Autotransporter beta-domain TSH58p_00970 e530d7144cbec84eded872b6c1ed601b 1279 SMART SM00869 1001 1269 1.6E-38 T 14-10-2018 IPR005546 Autotransporter beta-domain TSH58p_00970 e530d7144cbec84eded872b6c1ed601b 1279 SUPERFAMILY SSF51126 517 861 1.04E-6 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor TSH58p_00970 e530d7144cbec84eded872b6c1ed601b 1279 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 363 485 8.8E-10 T 14-10-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 TSH58p_00970 e530d7144cbec84eded872b6c1ed601b 1279 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 766 1278 3.2E-30 T 14-10-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 TSH58p_00970 e530d7144cbec84eded872b6c1ed601b 1279 SUPERFAMILY SSF103515 941 1278 1.44E-50 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily TSH58p_14380 32119c7762e540f097d88e12436a3aed 236 SUPERFAMILY SSF47090 187 231 2.28E-9 T 14-10-2018 IPR036365 PGBD-like superfamily TSH58p_14380 32119c7762e540f097d88e12436a3aed 236 SUPERFAMILY SSF55846 11 166 8.51E-56 T 14-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 TSH58p_14380 32119c7762e540f097d88e12436a3aed 236 Gene3D G3DSA:3.40.80.10 6 162 8.9E-52 T 14-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 TSH58p_14380 32119c7762e540f097d88e12436a3aed 236 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 25 150 3.5E-33 T 14-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 TSH58p_14380 32119c7762e540f097d88e12436a3aed 236 SMART SM00644 13 150 2.8E-42 T 14-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 TSH58p_14380 32119c7762e540f097d88e12436a3aed 236 Gene3D G3DSA:1.10.101.10 166 234 2.8E-8 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 TSH58p_29755 a3ae03e6ccafe1e4bf6d9d6d163a3530 1039 SUPERFAMILY SSF82693 553 648 2.88E-23 T 14-10-2018 TSH58p_29755 a3ae03e6ccafe1e4bf6d9d6d163a3530 1039 Pfam PF00873 AcrB/AcrD/AcrF family 4 1015 0.0 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_29755 a3ae03e6ccafe1e4bf6d9d6d163a3530 1039 SUPERFAMILY SSF82693 135 323 4.08E-27 T 14-10-2018 TSH58p_29755 a3ae03e6ccafe1e4bf6d9d6d163a3530 1039 Gene3D G3DSA:1.20.1640.10 10 500 0.0 T 14-10-2018 TSH58p_29755 a3ae03e6ccafe1e4bf6d9d6d163a3530 1039 Gene3D G3DSA:3.30.70.1430 40 806 0.0 T 14-10-2018 TSH58p_29755 a3ae03e6ccafe1e4bf6d9d6d163a3530 1039 Gene3D G3DSA:3.30.70.1430 555 647 0.0 T 14-10-2018 TSH58p_29755 a3ae03e6ccafe1e4bf6d9d6d163a3530 1039 Gene3D G3DSA:3.30.70.1440 648 855 0.0 T 14-10-2018 TSH58p_29755 a3ae03e6ccafe1e4bf6d9d6d163a3530 1039 Gene3D G3DSA:3.30.2090.10 178 268 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_29755 a3ae03e6ccafe1e4bf6d9d6d163a3530 1039 Gene3D G3DSA:1.20.1640.10 501 1012 0.0 T 14-10-2018 TSH58p_29755 a3ae03e6ccafe1e4bf6d9d6d163a3530 1039 SUPERFAMILY SSF82866 291 489 1.31E-50 T 14-10-2018 TSH58p_29755 a3ae03e6ccafe1e4bf6d9d6d163a3530 1039 PRINTS PR00702 Acriflavin resistance protein family signature 384 408 9.8E-82 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_29755 a3ae03e6ccafe1e4bf6d9d6d163a3530 1039 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 9.8E-82 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_29755 a3ae03e6ccafe1e4bf6d9d6d163a3530 1039 PRINTS PR00702 Acriflavin resistance protein family signature 437 460 9.8E-82 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_29755 a3ae03e6ccafe1e4bf6d9d6d163a3530 1039 PRINTS PR00702 Acriflavin resistance protein family signature 329 352 9.8E-82 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_29755 a3ae03e6ccafe1e4bf6d9d6d163a3530 1039 PRINTS PR00702 Acriflavin resistance protein family signature 540 557 9.8E-82 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_29755 a3ae03e6ccafe1e4bf6d9d6d163a3530 1039 PRINTS PR00702 Acriflavin resistance protein family signature 356 377 9.8E-82 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_29755 a3ae03e6ccafe1e4bf6d9d6d163a3530 1039 PRINTS PR00702 Acriflavin resistance protein family signature 462 485 9.8E-82 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_29755 a3ae03e6ccafe1e4bf6d9d6d163a3530 1039 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 9.8E-82 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_29755 a3ae03e6ccafe1e4bf6d9d6d163a3530 1039 PRINTS PR00702 Acriflavin resistance protein family signature 603 617 9.8E-82 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_29755 a3ae03e6ccafe1e4bf6d9d6d163a3530 1039 SUPERFAMILY SSF82714 183 264 2.09E-18 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_29755 a3ae03e6ccafe1e4bf6d9d6d163a3530 1039 Gene3D G3DSA:3.30.2090.10 698 798 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_29755 a3ae03e6ccafe1e4bf6d9d6d163a3530 1039 SUPERFAMILY SSF82866 795 1019 5.62E-48 T 14-10-2018 TSH58p_29755 a3ae03e6ccafe1e4bf6d9d6d163a3530 1039 SUPERFAMILY SSF82693 40 134 3.4E-25 T 14-10-2018 TSH58p_29755 a3ae03e6ccafe1e4bf6d9d6d163a3530 1039 SUPERFAMILY SSF82714 699 794 2.49E-15 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_29755 a3ae03e6ccafe1e4bf6d9d6d163a3530 1039 Gene3D G3DSA:3.30.70.1320 134 325 0.0 T 14-10-2018 TSH58p_01345 ff767174079162625e75f76f741eca8a 248 SUPERFAMILY SSF52096 2 230 1.07E-45 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_01345 ff767174079162625e75f76f741eca8a 248 Gene3D G3DSA:3.90.226.10 6 240 1.2E-45 T 14-10-2018 TSH58p_01345 ff767174079162625e75f76f741eca8a 248 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 192 5.9E-30 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TSH58p_09320 4a2eb60a15f3858ae1ef9e7e83ac8f34 258 Gene3D G3DSA:1.10.1060.10 129 258 1.0E-57 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSH58p_09320 4a2eb60a15f3858ae1ef9e7e83ac8f34 258 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 170 181 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_09320 4a2eb60a15f3858ae1ef9e7e83ac8f34 258 SUPERFAMILY SSF46548 130 257 1.92E-37 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSH58p_09320 4a2eb60a15f3858ae1ef9e7e83ac8f34 258 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 80 88 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 TSH58p_09320 4a2eb60a15f3858ae1ef9e7e83ac8f34 258 Gene3D G3DSA:3.10.20.30 17 128 1.4E-43 T 14-10-2018 IPR012675 Beta-grasp domain superfamily TSH58p_09320 4a2eb60a15f3858ae1ef9e7e83ac8f34 258 Pfam PF13534 4Fe-4S dicluster domain 169 242 4.7E-9 T 14-10-2018 TSH58p_09320 4a2eb60a15f3858ae1ef9e7e83ac8f34 258 SUPERFAMILY SSF54292 27 128 1.48E-31 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TSH58p_09320 4a2eb60a15f3858ae1ef9e7e83ac8f34 258 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 29 133 8.2E-32 T 14-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_09320 4a2eb60a15f3858ae1ef9e7e83ac8f34 258 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 32 251 2.1E-81 T 14-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_13435 9cdbfecf8affa427830d92eb228b8a52 92 Pfam PF10387 Protein of unknown function (DUF2442) 13 81 1.5E-22 T 14-10-2018 IPR018841 Protein of unknown function DUF2442 TSH58p_13435 9cdbfecf8affa427830d92eb228b8a52 92 Gene3D G3DSA:3.30.2020.20 11 76 3.1E-17 T 14-10-2018 TSH58p_15170 113bd314eda555cc2a14ebd34559f9c4 206 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 8 206 32.628 T 14-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_15170 113bd314eda555cc2a14ebd34559f9c4 206 Gene3D G3DSA:3.40.1370.10 1 206 1.8E-71 T 14-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 TSH58p_15170 113bd314eda555cc2a14ebd34559f9c4 206 SUPERFAMILY SSF52166 1 205 3.66E-70 T 14-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 TSH58p_15170 113bd314eda555cc2a14ebd34559f9c4 206 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 16 202 5.7E-71 T 14-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_15170 113bd314eda555cc2a14ebd34559f9c4 206 Pfam PF00573 Ribosomal protein L4/L1 family 16 203 3.8E-63 T 14-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 TSH58p_31575 67ef236ad75b3094889c96d6f439a605 409 Gene3D G3DSA:1.10.287.470 117 190 1.2E-95 T 14-10-2018 TSH58p_31575 67ef236ad75b3094889c96d6f439a605 409 Gene3D G3DSA:2.40.30.170 71 325 1.2E-95 T 14-10-2018 TSH58p_31575 67ef236ad75b3094889c96d6f439a605 409 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 65 396 1.6E-77 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 TSH58p_31575 67ef236ad75b3094889c96d6f439a605 409 Pfam PF13533 Biotin-lipoyl like 84 129 4.5E-12 T 14-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain TSH58p_31575 67ef236ad75b3094889c96d6f439a605 409 Gene3D G3DSA:2.40.420.20 326 394 1.2E-95 T 14-10-2018 TSH58p_31575 67ef236ad75b3094889c96d6f439a605 409 SUPERFAMILY SSF111369 72 320 1.7E-65 T 14-10-2018 TSH58p_31575 67ef236ad75b3094889c96d6f439a605 409 Gene3D G3DSA:2.40.50.100 82 229 1.2E-95 T 14-10-2018 TSH58p_32545 b14c3bebadd67434e78382318cc202ce 244 Pfam PF02585 GlcNAc-PI de-N-acetylase 8 136 1.4E-20 T 14-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 TSH58p_32545 b14c3bebadd67434e78382318cc202ce 244 Gene3D G3DSA:3.40.50.10320 4 244 5.4E-80 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TSH58p_32545 b14c3bebadd67434e78382318cc202ce 244 SUPERFAMILY SSF102588 4 243 4.58E-46 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TSH58p_24120 d738433f49b0fc88137239dfcff58aa7 511 Gene3D G3DSA:3.90.780.10 316 511 3.2E-46 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSH58p_24120 d738433f49b0fc88137239dfcff58aa7 511 Pfam PF02872 5'-nucleotidase, C-terminal domain 315 471 1.1E-39 T 14-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSH58p_24120 d738433f49b0fc88137239dfcff58aa7 511 Gene3D G3DSA:3.60.21.10 38 314 1.1E-31 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like TSH58p_24120 d738433f49b0fc88137239dfcff58aa7 511 PRINTS PR01607 Apyrase family signature 372 395 2.4E-7 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSH58p_24120 d738433f49b0fc88137239dfcff58aa7 511 PRINTS PR01607 Apyrase family signature 445 464 2.4E-7 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSH58p_24120 d738433f49b0fc88137239dfcff58aa7 511 SUPERFAMILY SSF55816 313 509 1.09E-46 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSH58p_24120 d738433f49b0fc88137239dfcff58aa7 511 SUPERFAMILY SSF56300 46 309 2.4E-36 T 14-10-2018 TSH58p_05650 6b1070e89ee5739916a4ac927a3f5461 164 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase [moaC]. 7 163 37.729 T 14-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_05650 6b1070e89ee5739916a4ac927a3f5461 164 Gene3D G3DSA:3.30.70.640 6 164 3.4E-71 T 14-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_05650 6b1070e89ee5739916a4ac927a3f5461 164 Pfam PF01967 MoaC family 20 155 4.0E-57 T 14-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_05650 6b1070e89ee5739916a4ac927a3f5461 164 SUPERFAMILY SSF55040 16 160 1.01E-62 T 14-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_05650 6b1070e89ee5739916a4ac927a3f5461 164 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 9 157 5.5E-66 T 14-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_16055 69fea10f54c28db8aa506d918684c0ed 124 Pfam PF06170 Protein of unknown function (DUF983) 28 112 2.3E-31 T 14-10-2018 IPR009325 Protein of unknown function DUF983 TSH58p_18780 5c65bac6c1dab7098bee000da5fb3322 843 SUPERFAMILY SSF81442 36 531 7.72E-149 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_18780 5c65bac6c1dab7098bee000da5fb3322 843 PRINTS PR01165 Cytochrome c oxidase subunit I signature 368 386 1.3E-78 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_18780 5c65bac6c1dab7098bee000da5fb3322 843 PRINTS PR01165 Cytochrome c oxidase subunit I signature 309 324 1.3E-78 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_18780 5c65bac6c1dab7098bee000da5fb3322 843 PRINTS PR01165 Cytochrome c oxidase subunit I signature 82 105 1.3E-78 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_18780 5c65bac6c1dab7098bee000da5fb3322 843 PRINTS PR01165 Cytochrome c oxidase subunit I signature 183 201 1.3E-78 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_18780 5c65bac6c1dab7098bee000da5fb3322 843 PRINTS PR01165 Cytochrome c oxidase subunit I signature 212 231 1.3E-78 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_18780 5c65bac6c1dab7098bee000da5fb3322 843 PRINTS PR01165 Cytochrome c oxidase subunit I signature 263 284 1.3E-78 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_18780 5c65bac6c1dab7098bee000da5fb3322 843 PRINTS PR01165 Cytochrome c oxidase subunit I signature 446 467 1.3E-78 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_18780 5c65bac6c1dab7098bee000da5fb3322 843 PRINTS PR01165 Cytochrome c oxidase subunit I signature 109 133 1.3E-78 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_18780 5c65bac6c1dab7098bee000da5fb3322 843 PRINTS PR01165 Cytochrome c oxidase subunit I signature 396 415 1.3E-78 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_18780 5c65bac6c1dab7098bee000da5fb3322 843 PRINTS PR01165 Cytochrome c oxidase subunit I signature 151 163 1.3E-78 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_18780 5c65bac6c1dab7098bee000da5fb3322 843 PRINTS PR01165 Cytochrome c oxidase subunit I signature 333 354 1.3E-78 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_18780 5c65bac6c1dab7098bee000da5fb3322 843 Gene3D G3DSA:1.20.120.80 656 839 1.6E-8 T 14-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_18780 5c65bac6c1dab7098bee000da5fb3322 843 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 265 319 - T 14-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_18780 5c65bac6c1dab7098bee000da5fb3322 843 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 45 490 1.0E-132 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_18780 5c65bac6c1dab7098bee000da5fb3322 843 Gene3D G3DSA:1.20.210.10 25 547 2.8E-171 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_18780 5c65bac6c1dab7098bee000da5fb3322 843 SUPERFAMILY SSF81452 660 821 3.66E-12 T 14-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_18780 5c65bac6c1dab7098bee000da5fb3322 843 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 38 535 9.6E-205 T 14-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 TSH58p_01290 5ebdceee05562037c22ff438a3055671 456 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 342 446 3.4E-22 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TSH58p_01290 5ebdceee05562037c22ff438a3055671 456 Gene3D G3DSA:3.30.390.30 341 454 2.2E-28 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TSH58p_01290 5ebdceee05562037c22ff438a3055671 456 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 317 8.3E-56 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSH58p_01290 5ebdceee05562037c22ff438a3055671 456 SUPERFAMILY SSF55424 341 449 1.89E-29 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TSH58p_01290 5ebdceee05562037c22ff438a3055671 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 6.7E-25 T 14-10-2018 TSH58p_01290 5ebdceee05562037c22ff438a3055671 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 130 148 6.7E-25 T 14-10-2018 TSH58p_01290 5ebdceee05562037c22ff438a3055671 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 6.7E-25 T 14-10-2018 TSH58p_01290 5ebdceee05562037c22ff438a3055671 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 285 307 6.7E-25 T 14-10-2018 TSH58p_01290 5ebdceee05562037c22ff438a3055671 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 272 6.7E-25 T 14-10-2018 TSH58p_01290 5ebdceee05562037c22ff438a3055671 456 Gene3D G3DSA:3.50.50.60 3 326 2.0E-101 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_01290 5ebdceee05562037c22ff438a3055671 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 35 50 6.7E-47 T 14-10-2018 TSH58p_01290 5ebdceee05562037c22ff438a3055671 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 133 142 6.7E-47 T 14-10-2018 TSH58p_01290 5ebdceee05562037c22ff438a3055671 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 257 271 6.7E-47 T 14-10-2018 TSH58p_01290 5ebdceee05562037c22ff438a3055671 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 401 416 6.7E-47 T 14-10-2018 TSH58p_01290 5ebdceee05562037c22ff438a3055671 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 336 357 6.7E-47 T 14-10-2018 TSH58p_01290 5ebdceee05562037c22ff438a3055671 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 194 6.7E-47 T 14-10-2018 TSH58p_01290 5ebdceee05562037c22ff438a3055671 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 6.7E-47 T 14-10-2018 TSH58p_01290 5ebdceee05562037c22ff438a3055671 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 300 307 6.7E-47 T 14-10-2018 TSH58p_01290 5ebdceee05562037c22ff438a3055671 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 423 443 6.7E-47 T 14-10-2018 TSH58p_01290 5ebdceee05562037c22ff438a3055671 456 SUPERFAMILY SSF51905 2 360 2.07E-51 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_01290 5ebdceee05562037c22ff438a3055671 456 PIRSF PIRSF000350 1 424 7.3E-86 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 TSH58p_01290 5ebdceee05562037c22ff438a3055671 456 Gene3D G3DSA:3.50.50.60 142 263 2.0E-101 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_05545 6ce1ee811918579e92a7d5b4b4bdc760 309 Pfam PF12706 Beta-lactamase superfamily domain 51 276 8.9E-48 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_05545 6ce1ee811918579e92a7d5b4b4bdc760 309 Gene3D G3DSA:3.60.15.10 1 309 3.0E-81 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_05545 6ce1ee811918579e92a7d5b4b4bdc760 309 Hamap MF_00653 Coenzyme PQQ synthesis protein B [pqqB]. 1 309 150.941 T 14-10-2018 IPR011842 Coenzyme PQQ biosynthesis protein B TSH58p_05545 6ce1ee811918579e92a7d5b4b4bdc760 309 TIGRFAM TIGR02108 PQQ_syn_pqqB: coenzyme PQQ biosynthesis protein B 4 309 2.7E-118 T 14-10-2018 IPR011842 Coenzyme PQQ biosynthesis protein B TSH58p_05545 6ce1ee811918579e92a7d5b4b4bdc760 309 SUPERFAMILY SSF56281 3 309 2.66E-57 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_28840 26ebc7ad70479365885d121d2b5ca6cd 332 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 218 4.0E-47 T 14-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 TSH58p_28840 26ebc7ad70479365885d121d2b5ca6cd 332 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 226 323 4.1E-19 T 14-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal TSH58p_28840 26ebc7ad70479365885d121d2b5ca6cd 332 Gene3D G3DSA:3.30.465.10 1 219 2.0E-82 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TSH58p_28840 26ebc7ad70479365885d121d2b5ca6cd 332 SUPERFAMILY SSF55447 224 325 3.66E-30 T 14-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily TSH58p_28840 26ebc7ad70479365885d121d2b5ca6cd 332 Gene3D G3DSA:3.30.390.50 222 326 3.6E-28 T 14-10-2018 TSH58p_28840 26ebc7ad70479365885d121d2b5ca6cd 332 SUPERFAMILY SSF56176 1 218 1.69E-61 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TSH58p_28840 26ebc7ad70479365885d121d2b5ca6cd 332 SMART SM01092 225 323 2.0E-32 T 14-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal TSH58p_26435 621b85b5300cf68849de6401dc36daaf 366 PIRSF PIRSF000876 4 363 3.5E-97 T 14-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 TSH58p_26435 621b85b5300cf68849de6401dc36daaf 366 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 7 360 30.761 T 14-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 TSH58p_26435 621b85b5300cf68849de6401dc36daaf 366 Gene3D G3DSA:3.40.50.12740 7 157 3.6E-25 T 14-10-2018 TSH58p_26435 621b85b5300cf68849de6401dc36daaf 366 SUPERFAMILY SSF52172 5 114 3.98E-25 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_26435 621b85b5300cf68849de6401dc36daaf 366 SUPERFAMILY SSF52738 177 360 1.01E-54 T 14-10-2018 IPR035909 Methylesterase CheB, C-terminal TSH58p_26435 621b85b5300cf68849de6401dc36daaf 366 Pfam PF00072 Response regulator receiver domain 9 113 1.2E-19 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_26435 621b85b5300cf68849de6401dc36daaf 366 SMART SM00448 7 122 2.5E-16 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_26435 621b85b5300cf68849de6401dc36daaf 366 Pfam PF01339 CheB methylesterase 182 355 2.2E-50 T 14-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 TSH58p_26435 621b85b5300cf68849de6401dc36daaf 366 Gene3D G3DSA:3.40.50.180 172 364 2.6E-57 T 14-10-2018 IPR035909 Methylesterase CheB, C-terminal TSH58p_17245 9c4e980d30f00bef4ee06e181b073046 436 SUPERFAMILY SSF53383 15 434 1.93E-182 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_17245 9c4e980d30f00bef4ee06e181b073046 436 PIRSF PIRSF000412 5 436 1.7E-169 T 14-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TSH58p_17245 9c4e980d30f00bef4ee06e181b073046 436 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 19 434 53.624 T 14-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TSH58p_17245 9c4e980d30f00bef4ee06e181b073046 436 Pfam PF00464 Serine hydroxymethyltransferase 20 397 1.1E-178 T 14-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TSH58p_17245 9c4e980d30f00bef4ee06e181b073046 436 Gene3D G3DSA:3.90.1150.10 22 405 1.8E-183 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_17245 9c4e980d30f00bef4ee06e181b073046 436 Gene3D G3DSA:3.40.640.10 49 300 1.8E-183 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_17245 9c4e980d30f00bef4ee06e181b073046 436 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 234 250 - T 14-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TSH58p_14830 7ac7006d8cfc3fc3ff42ca4a942c507f 479 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 151 362 2.6E-25 T 14-10-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT TSH58p_14830 7ac7006d8cfc3fc3ff42ca4a942c507f 479 PIRSF PIRSF016636 1 479 1.3E-131 T 14-10-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB TSH58p_14830 7ac7006d8cfc3fc3ff42ca4a942c507f 479 PIRSF PIRSF500217 1 479 1.4E-133 T 14-10-2018 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 TSH58p_09335 c92550ee14013c7ea63f1c887866cb06 129 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 6 120 4.2E-32 T 14-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_09335 c92550ee14013c7ea63f1c887866cb06 129 ProSitePatterns PS01001 Succinate dehydrogenase cytochrome b subunit signature 2. 82 95 - T 14-10-2018 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_09335 c92550ee14013c7ea63f1c887866cb06 129 Gene3D G3DSA:1.20.1300.10 2 129 2.2E-42 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_09335 c92550ee14013c7ea63f1c887866cb06 129 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 7 124 8.6E-40 T 14-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_09335 c92550ee14013c7ea63f1c887866cb06 129 PIRSF PIRSF000178 1 126 2.4E-38 T 14-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_09335 c92550ee14013c7ea63f1c887866cb06 129 SUPERFAMILY SSF81343 6 123 4.91E-35 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_11125 39ee6264b4802c3cb1ecf6f02b8e717f 113 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 13 96 2.0E-33 T 14-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 TSH58p_11125 39ee6264b4802c3cb1ecf6f02b8e717f 113 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 15 99 2.3E-20 T 14-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 TSH58p_11125 39ee6264b4802c3cb1ecf6f02b8e717f 113 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 10 96 20.629 T 14-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 TSH58p_11125 39ee6264b4802c3cb1ecf6f02b8e717f 113 Gene3D G3DSA:1.10.287.1080 9 102 5.1E-32 T 14-10-2018 TSH58p_11125 39ee6264b4802c3cb1ecf6f02b8e717f 113 SUPERFAMILY SSF101386 12 100 1.72E-26 T 14-10-2018 TSH58p_20840 08bc0cdffe06e5860cfac911812d9236 523 Gene3D G3DSA:3.50.50.60 440 522 1.6E-13 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_20840 08bc0cdffe06e5860cfac911812d9236 523 SUPERFAMILY SSF54373 292 459 1.77E-15 T 14-10-2018 TSH58p_20840 08bc0cdffe06e5860cfac911812d9236 523 Gene3D G3DSA:3.50.50.60 10 166 1.5E-14 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_20840 08bc0cdffe06e5860cfac911812d9236 523 SUPERFAMILY SSF51905 13 519 2.43E-58 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_20840 08bc0cdffe06e5860cfac911812d9236 523 Pfam PF00732 GMC oxidoreductase 19 304 9.9E-17 T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 TSH58p_20840 08bc0cdffe06e5860cfac911812d9236 523 Gene3D G3DSA:3.50.50.60 208 328 4.3E-7 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_20840 08bc0cdffe06e5860cfac911812d9236 523 Pfam PF05199 GMC oxidoreductase 391 509 3.1E-21 T 14-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 TSH58p_12865 e3f6931e43b086e936c421d60c42bfa2 212 Pfam PF01202 Shikimate kinase 28 184 2.1E-46 T 14-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 TSH58p_12865 e3f6931e43b086e936c421d60c42bfa2 212 Hamap MF_00109 Shikimate kinase [aroK]. 19 185 28.412 T 14-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 TSH58p_12865 e3f6931e43b086e936c421d60c42bfa2 212 PRINTS PR01100 Shikimate kinase family signature 22 37 3.8E-20 T 14-10-2018 TSH58p_12865 e3f6931e43b086e936c421d60c42bfa2 212 PRINTS PR01100 Shikimate kinase family signature 114 131 3.8E-20 T 14-10-2018 TSH58p_12865 e3f6931e43b086e936c421d60c42bfa2 212 PRINTS PR01100 Shikimate kinase family signature 46 59 3.8E-20 T 14-10-2018 TSH58p_12865 e3f6931e43b086e936c421d60c42bfa2 212 PRINTS PR01100 Shikimate kinase family signature 74 82 3.8E-20 T 14-10-2018 TSH58p_12865 e3f6931e43b086e936c421d60c42bfa2 212 PRINTS PR01100 Shikimate kinase family signature 93 102 3.8E-20 T 14-10-2018 TSH58p_12865 e3f6931e43b086e936c421d60c42bfa2 212 ProSitePatterns PS01128 Shikimate kinase signature. 75 101 - T 14-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 TSH58p_12865 e3f6931e43b086e936c421d60c42bfa2 212 Gene3D G3DSA:3.40.50.300 20 202 1.6E-51 T 14-10-2018 TSH58p_12865 e3f6931e43b086e936c421d60c42bfa2 212 SUPERFAMILY SSF52540 19 186 9.67E-26 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_19625 da4821973d8424c872ef44065b1c469d 255 Gene3D G3DSA:3.40.50.300 1 250 3.5E-64 T 14-10-2018 TSH58p_19625 da4821973d8424c872ef44065b1c469d 255 SUPERFAMILY SSF52540 4 249 4.71E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_19625 da4821973d8424c872ef44065b1c469d 255 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 227 249 1.2E-11 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSH58p_19625 da4821973d8424c872ef44065b1c469d 255 Pfam PF00005 ABC transporter 22 178 7.8E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_19625 da4821973d8424c872ef44065b1c469d 255 SMART SM00382 30 226 7.0E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_27845 911aa407e7fe5733572208349c3cbfe3 426 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 8 416 2.9E-116 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TSH58p_27845 911aa407e7fe5733572208349c3cbfe3 426 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 419 1.2E-136 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSH58p_27845 911aa407e7fe5733572208349c3cbfe3 426 PIRSF PIRSF006066 1 425 4.9E-137 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSH58p_00995 16cd585233ec47eb39d32d8ae1986a46 359 SUPERFAMILY SSF52540 4 243 3.59E-82 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_00995 16cd585233ec47eb39d32d8ae1986a46 359 SMART SM00382 28 223 2.2E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_00995 16cd585233ec47eb39d32d8ae1986a46 359 Gene3D G3DSA:2.40.50.140 245 279 5.3E-5 T 14-10-2018 TSH58p_00995 16cd585233ec47eb39d32d8ae1986a46 359 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_00995 16cd585233ec47eb39d32d8ae1986a46 359 Gene3D G3DSA:2.40.50.100 280 332 5.3E-5 T 14-10-2018 TSH58p_00995 16cd585233ec47eb39d32d8ae1986a46 359 Pfam PF08402 TOBE domain 277 355 2.3E-12 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TSH58p_00995 16cd585233ec47eb39d32d8ae1986a46 359 Gene3D G3DSA:3.40.50.300 1 241 3.1E-74 T 14-10-2018 TSH58p_00995 16cd585233ec47eb39d32d8ae1986a46 359 Pfam PF00005 ABC transporter 19 165 7.6E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_00995 16cd585233ec47eb39d32d8ae1986a46 359 SUPERFAMILY SSF50331 241 354 5.38E-13 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSH58p_32635 a1286ddb6822cab2096bd1642fd23be4 307 Pfam PF01497 Periplasmic binding protein 42 282 9.3E-13 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain TSH58p_32635 a1286ddb6822cab2096bd1642fd23be4 307 Gene3D G3DSA:3.40.50.1980 38 123 4.5E-14 T 14-10-2018 TSH58p_32635 a1286ddb6822cab2096bd1642fd23be4 307 SUPERFAMILY SSF53807 40 300 8.24E-40 T 14-10-2018 TSH58p_32635 a1286ddb6822cab2096bd1642fd23be4 307 Gene3D G3DSA:3.40.50.1980 135 304 1.6E-45 T 14-10-2018 TSH58p_32635 a1286ddb6822cab2096bd1642fd23be4 307 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 218 236 4.3E-15 T 14-10-2018 TSH58p_32635 a1286ddb6822cab2096bd1642fd23be4 307 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 283 296 4.3E-15 T 14-10-2018 TSH58p_32635 a1286ddb6822cab2096bd1642fd23be4 307 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 57 75 4.3E-15 T 14-10-2018 TSH58p_32635 a1286ddb6822cab2096bd1642fd23be4 307 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 194 209 4.3E-15 T 14-10-2018 TSH58p_32635 a1286ddb6822cab2096bd1642fd23be4 307 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 88 103 4.3E-15 T 14-10-2018 TSH58p_30185 a1286ddb6822cab2096bd1642fd23be4 307 Pfam PF01497 Periplasmic binding protein 42 282 9.3E-13 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain TSH58p_30185 a1286ddb6822cab2096bd1642fd23be4 307 Gene3D G3DSA:3.40.50.1980 38 123 4.5E-14 T 14-10-2018 TSH58p_30185 a1286ddb6822cab2096bd1642fd23be4 307 SUPERFAMILY SSF53807 40 300 8.24E-40 T 14-10-2018 TSH58p_30185 a1286ddb6822cab2096bd1642fd23be4 307 Gene3D G3DSA:3.40.50.1980 135 304 1.6E-45 T 14-10-2018 TSH58p_30185 a1286ddb6822cab2096bd1642fd23be4 307 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 218 236 4.3E-15 T 14-10-2018 TSH58p_30185 a1286ddb6822cab2096bd1642fd23be4 307 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 283 296 4.3E-15 T 14-10-2018 TSH58p_30185 a1286ddb6822cab2096bd1642fd23be4 307 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 57 75 4.3E-15 T 14-10-2018 TSH58p_30185 a1286ddb6822cab2096bd1642fd23be4 307 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 194 209 4.3E-15 T 14-10-2018 TSH58p_30185 a1286ddb6822cab2096bd1642fd23be4 307 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 88 103 4.3E-15 T 14-10-2018 TSH58p_15570 d6d9b97764cbc887cb48a163993850bc 397 Pfam PF05762 VWA domain containing CoxE-like protein 191 279 1.5E-9 T 14-10-2018 IPR008912 Uncharacterised protein family CoxE-like TSH58p_07075 24d2577e6a7dfaa10f890cb389e3292f 165 Pfam PF01799 [2Fe-2S] binding domain 73 145 9.8E-26 T 14-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 TSH58p_07075 24d2577e6a7dfaa10f890cb389e3292f 165 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 63 1.3E-9 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 TSH58p_07075 24d2577e6a7dfaa10f890cb389e3292f 165 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 39 47 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 TSH58p_07075 24d2577e6a7dfaa10f890cb389e3292f 165 Gene3D G3DSA:3.10.20.30 1 74 2.1E-29 T 14-10-2018 IPR012675 Beta-grasp domain superfamily TSH58p_07075 24d2577e6a7dfaa10f890cb389e3292f 165 SUPERFAMILY SSF47741 84 154 1.57E-27 T 14-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily TSH58p_07075 24d2577e6a7dfaa10f890cb389e3292f 165 Gene3D G3DSA:1.10.150.120 75 162 1.4E-26 T 14-10-2018 TSH58p_07075 24d2577e6a7dfaa10f890cb389e3292f 165 SUPERFAMILY SSF54292 2 78 8.78E-26 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TSH58p_13560 a5f747246f7cbb8e219f7835ddda63eb 535 Pfam PF05235 CHAD domain 238 478 1.1E-59 T 14-10-2018 IPR007899 CHAD domain TSH58p_13560 a5f747246f7cbb8e219f7835ddda63eb 535 Pfam PF01928 CYTH domain 8 206 3.1E-25 T 14-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 TSH58p_13560 a5f747246f7cbb8e219f7835ddda63eb 535 SMART SM01118 8 212 1.5E-30 T 14-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 TSH58p_13560 a5f747246f7cbb8e219f7835ddda63eb 535 SUPERFAMILY SSF55154 8 217 2.45E-38 T 14-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 TSH58p_13560 a5f747246f7cbb8e219f7835ddda63eb 535 Gene3D G3DSA:2.40.320.10 5 209 6.5E-26 T 14-10-2018 TSH58p_13560 a5f747246f7cbb8e219f7835ddda63eb 535 Gene3D G3DSA:1.40.20.10 216 530 2.3E-82 T 14-10-2018 IPR038186 CHAD domain superfamily TSH58p_13560 a5f747246f7cbb8e219f7835ddda63eb 535 SMART SM00880 237 513 1.4E-75 T 14-10-2018 IPR007899 CHAD domain TSH58p_26120 2b3918fa6aee670499f34a7c394401e4 202 Gene3D G3DSA:1.10.10.10 41 155 7.3E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_26120 2b3918fa6aee670499f34a7c394401e4 202 Pfam PF03551 Transcriptional regulator PadR-like family 62 131 9.3E-15 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal TSH58p_26120 2b3918fa6aee670499f34a7c394401e4 202 SUPERFAMILY SSF46785 58 171 1.21E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_31840 351ac29f0242d1b8ea9482d3baf5a4c3 321 Gene3D G3DSA:2.40.400.10 31 165 2.6E-5 T 14-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 TSH58p_31840 351ac29f0242d1b8ea9482d3baf5a4c3 321 Pfam PF06314 Acetoacetate decarboxylase (ADC) 28 145 3.5E-8 T 14-10-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 TSH58p_31840 351ac29f0242d1b8ea9482d3baf5a4c3 321 SUPERFAMILY SSF160104 19 272 2.75E-10 T 14-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 TSH58p_19355 bb0d571fa4433476a4dec3417e86da9a 888 PIRSF PIRSF000157 88 874 6.2E-288 T 14-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 TSH58p_19355 bb0d571fa4433476a4dec3417e86da9a 888 PIRSF PIRSF000157 1 97 0.18 T 14-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 TSH58p_19355 bb0d571fa4433476a4dec3417e86da9a 888 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 5 42 3.9E-11 T 14-10-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 TSH58p_19355 bb0d571fa4433476a4dec3417e86da9a 888 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 96 871 7.5E-242 T 14-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 TSH58p_19355 bb0d571fa4433476a4dec3417e86da9a 888 SMART SM00861 533 726 3.8E-51 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSH58p_19355 bb0d571fa4433476a4dec3417e86da9a 888 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 731 872 1.0E-33 T 14-10-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 TSH58p_19355 bb0d571fa4433476a4dec3417e86da9a 888 SUPERFAMILY SSF52518 528 732 2.69E-47 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_19355 bb0d571fa4433476a4dec3417e86da9a 888 Pfam PF02779 Transketolase, pyrimidine binding domain 532 725 5.6E-61 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSH58p_19355 bb0d571fa4433476a4dec3417e86da9a 888 Gene3D G3DSA:3.40.50.12470 498 749 3.1E-145 T 14-10-2018 TSH58p_19355 bb0d571fa4433476a4dec3417e86da9a 888 Gene3D G3DSA:3.40.50.11610 669 870 3.1E-145 T 14-10-2018 TSH58p_19355 bb0d571fa4433476a4dec3417e86da9a 888 Pfam PF00676 Dehydrogenase E1 component 152 467 1.3E-42 T 14-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 TSH58p_19355 bb0d571fa4433476a4dec3417e86da9a 888 SUPERFAMILY SSF52518 104 467 5.1E-61 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_19355 bb0d571fa4433476a4dec3417e86da9a 888 Gene3D G3DSA:3.40.50.970 108 473 8.7E-117 T 14-10-2018 TSH58p_15360 a21d3d35e6b1329bde1c6658c30b66a4 242 Pfam PF03963 Flagellar hook capping protein - N-terminal region 21 93 7.9E-21 T 14-10-2018 IPR005648 Flagellar hook capping protein TSH58p_15360 a21d3d35e6b1329bde1c6658c30b66a4 242 Gene3D G3DSA:2.30.30.910 111 236 2.2E-16 T 14-10-2018 TSH58p_15360 a21d3d35e6b1329bde1c6658c30b66a4 242 Gene3D G3DSA:2.60.40.4070 119 208 2.2E-16 T 14-10-2018 TSH58p_15360 a21d3d35e6b1329bde1c6658c30b66a4 242 Pfam PF13860 FlgD Ig-like domain 128 192 9.3E-12 T 14-10-2018 IPR025965 FlgD Ig-like domain TSH58p_15255 99131e40627e4f87fb982cbf7b7e270c 63 Gene3D G3DSA:3.30.1390.20 3 61 3.5E-24 T 14-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily TSH58p_15255 99131e40627e4f87fb982cbf7b7e270c 63 Pfam PF00327 Ribosomal protein L30p/L7e 8 57 1.5E-17 T 14-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain TSH58p_15255 99131e40627e4f87fb982cbf7b7e270c 63 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 3 61 18.818 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_15255 99131e40627e4f87fb982cbf7b7e270c 63 SUPERFAMILY SSF55129 5 60 1.29E-20 T 14-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily TSH58p_15255 99131e40627e4f87fb982cbf7b7e270c 63 PIRSF PIRSF002211 1 62 6.6E-27 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_15255 99131e40627e4f87fb982cbf7b7e270c 63 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 8 61 1.1E-26 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_24135 e29fa536f4a5f223fcfa597c7d305af0 484 SUPERFAMILY SSF48452 10 177 2.44E-25 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_24135 e29fa536f4a5f223fcfa597c7d305af0 484 Pfam PF13432 Tetratricopeptide repeat 145 192 0.0017 T 14-10-2018 TSH58p_24135 e29fa536f4a5f223fcfa597c7d305af0 484 Pfam PF13432 Tetratricopeptide repeat 17 72 9.5E-4 T 14-10-2018 TSH58p_24135 e29fa536f4a5f223fcfa597c7d305af0 484 Pfam PF13432 Tetratricopeptide repeat 77 140 6.8E-5 T 14-10-2018 TSH58p_24135 e29fa536f4a5f223fcfa597c7d305af0 484 SUPERFAMILY SSF53756 217 456 2.07E-21 T 14-10-2018 TSH58p_24135 e29fa536f4a5f223fcfa597c7d305af0 484 SMART SM00028 38 71 27.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24135 e29fa536f4a5f223fcfa597c7d305af0 484 SMART SM00028 106 139 1.5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24135 e29fa536f4a5f223fcfa597c7d305af0 484 SMART SM00028 140 173 50.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24135 e29fa536f4a5f223fcfa597c7d305af0 484 SMART SM00028 72 105 18.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24135 e29fa536f4a5f223fcfa597c7d305af0 484 Gene3D G3DSA:1.25.40.10 6 79 1.2E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_24135 e29fa536f4a5f223fcfa597c7d305af0 484 Gene3D G3DSA:3.40.50.2000 368 442 5.4E-6 T 14-10-2018 TSH58p_24135 e29fa536f4a5f223fcfa597c7d305af0 484 Gene3D G3DSA:1.25.40.10 80 199 9.9E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_20805 2b9e301974215146a2dfd02b8b561e4b 436 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 14 417 5.8E-116 T 14-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 TSH58p_20805 2b9e301974215146a2dfd02b8b561e4b 436 Pfam PF00860 Permease family 21 390 7.7E-97 T 14-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 TSH58p_20805 2b9e301974215146a2dfd02b8b561e4b 436 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 339 359 - T 14-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 TSH58p_09670 a599bfd0916fae1964d400763666cbb8 268 Pfam PF13581 Histidine kinase-like ATPase domain 130 265 5.3E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_09670 a599bfd0916fae1964d400763666cbb8 268 SUPERFAMILY SSF55874 147 255 2.62E-6 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_09670 a599bfd0916fae1964d400763666cbb8 268 Gene3D G3DSA:3.30.565.10 117 268 5.5E-16 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_19715 d4f1a215a88e8fc7f4f5c69dc78096bf 251 Gene3D G3DSA:3.30.70.20 7 247 1.9E-63 T 14-10-2018 TSH58p_19715 d4f1a215a88e8fc7f4f5c69dc78096bf 251 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 119 130 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_19715 d4f1a215a88e8fc7f4f5c69dc78096bf 251 SUPERFAMILY SSF54862 13 218 1.67E-64 T 14-10-2018 TSH58p_19715 d4f1a215a88e8fc7f4f5c69dc78096bf 251 Pfam PF13247 4Fe-4S dicluster domain 81 180 1.9E-24 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_19715 d4f1a215a88e8fc7f4f5c69dc78096bf 251 Pfam PF12800 4Fe-4S binding domain 21 35 0.1 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_09860 fc7690d4a01dec548998a96cf764d403 544 SMART SM00028 106 139 0.0027 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_09860 fc7690d4a01dec548998a96cf764d403 544 SMART SM00028 140 173 9.2E-5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_09860 fc7690d4a01dec548998a96cf764d403 544 SMART SM00028 38 71 14.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_09860 fc7690d4a01dec548998a96cf764d403 544 SMART SM00028 72 105 0.39 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_09860 fc7690d4a01dec548998a96cf764d403 544 SMART SM00028 208 241 2.5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_09860 fc7690d4a01dec548998a96cf764d403 544 SMART SM00028 174 207 4.9 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_09860 fc7690d4a01dec548998a96cf764d403 544 Gene3D G3DSA:1.25.40.10 6 251 7.5E-52 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_09860 fc7690d4a01dec548998a96cf764d403 544 Pfam PF13432 Tetratricopeptide repeat 11 72 1.5E-6 T 14-10-2018 TSH58p_09860 fc7690d4a01dec548998a96cf764d403 544 Pfam PF13432 Tetratricopeptide repeat 146 205 3.9E-10 T 14-10-2018 TSH58p_09860 fc7690d4a01dec548998a96cf764d403 544 Pfam PF13432 Tetratricopeptide repeat 78 140 6.8E-7 T 14-10-2018 TSH58p_09860 fc7690d4a01dec548998a96cf764d403 544 SUPERFAMILY SSF53335 257 538 3.65E-44 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_09860 fc7690d4a01dec548998a96cf764d403 544 Gene3D G3DSA:3.40.50.150 252 394 3.1E-45 T 14-10-2018 TSH58p_09860 fc7690d4a01dec548998a96cf764d403 544 Gene3D G3DSA:2.70.160.11 397 542 4.2E-30 T 14-10-2018 TSH58p_09860 fc7690d4a01dec548998a96cf764d403 544 SUPERFAMILY SSF48452 14 252 3.07E-37 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_09860 fc7690d4a01dec548998a96cf764d403 544 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 276 393 5.9E-10 T 14-10-2018 TSH58p_09940 fb8c2d89f1cd7f0f3d7350baa0953762 137 Pfam PF01878 EVE domain 3 131 1.7E-43 T 14-10-2018 IPR002740 EVE domain TSH58p_09940 fb8c2d89f1cd7f0f3d7350baa0953762 137 Gene3D G3DSA:3.10.590.10 1 137 4.8E-49 T 14-10-2018 TSH58p_09940 fb8c2d89f1cd7f0f3d7350baa0953762 137 SUPERFAMILY SSF88697 1 135 1.33E-51 T 14-10-2018 IPR015947 PUA-like superfamily TSH58p_01325 b6ace9625474e8fbc272f9013e0a9200 244 SUPERFAMILY SSF52540 11 237 2.38E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_01325 b6ace9625474e8fbc272f9013e0a9200 244 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_01325 b6ace9625474e8fbc272f9013e0a9200 244 SMART SM00382 38 232 6.2E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_01325 b6ace9625474e8fbc272f9013e0a9200 244 Pfam PF00005 ABC transporter 30 174 1.5E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_01325 b6ace9625474e8fbc272f9013e0a9200 244 Gene3D G3DSA:3.40.50.300 9 243 2.4E-59 T 14-10-2018 TSH58p_19380 ddbe34950a7c23e0d4803409e598e5c4 484 Pfam PF00171 Aldehyde dehydrogenase family 18 479 2.8E-151 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TSH58p_19380 ddbe34950a7c23e0d4803409e598e5c4 484 Gene3D G3DSA:3.40.309.10 256 448 2.7E-153 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TSH58p_19380 ddbe34950a7c23e0d4803409e598e5c4 484 SUPERFAMILY SSF53720 8 481 2.23E-149 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSH58p_19380 ddbe34950a7c23e0d4803409e598e5c4 484 Gene3D G3DSA:3.40.605.10 22 474 2.7E-153 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TSH58p_19380 ddbe34950a7c23e0d4803409e598e5c4 484 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 TSH58p_02215 58e95ce1c8b030aa4aa41d0e8e847384 427 SUPERFAMILY SSF75304 2 421 4.71E-114 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_02215 58e95ce1c8b030aa4aa41d0e8e847384 427 Gene3D G3DSA:3.90.1300.10 6 426 1.7E-125 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_02215 58e95ce1c8b030aa4aa41d0e8e847384 427 Pfam PF01425 Amidase 25 415 2.9E-80 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_13055 cc8050e511e170a149977e21e3c14bac 194 SMART SM00448 22 133 4.4E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_13055 cc8050e511e170a149977e21e3c14bac 194 SUPERFAMILY SSF52172 23 179 8.82E-32 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_13055 cc8050e511e170a149977e21e3c14bac 194 Pfam PF00072 Response regulator receiver domain 25 132 1.1E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_13055 cc8050e511e170a149977e21e3c14bac 194 Gene3D G3DSA:3.40.50.2300 22 134 5.9E-28 T 14-10-2018 TSH58p_13055 cc8050e511e170a149977e21e3c14bac 194 Gene3D G3DSA:1.10.10.60 135 193 4.1E-25 T 14-10-2018 TSH58p_13055 cc8050e511e170a149977e21e3c14bac 194 Pfam PF02954 Bacterial regulatory protein, Fis family 156 189 1.3E-5 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_17895 32bf47a5ccdd2f3b342ae8565cd1c8b1 624 SUPERFAMILY SSF52540 446 619 1.33E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_17895 32bf47a5ccdd2f3b342ae8565cd1c8b1 624 Hamap MF_00062 Sulfate adenylyltransferase subunit 1 [cysN]. 5 449 49.968 T 14-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 TSH58p_17895 32bf47a5ccdd2f3b342ae8565cd1c8b1 624 SUPERFAMILY SSF50465 318 421 9.59E-33 T 14-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal TSH58p_17895 32bf47a5ccdd2f3b342ae8565cd1c8b1 624 Gene3D G3DSA:2.40.30.10 317 421 5.0E-34 T 14-10-2018 TSH58p_17895 32bf47a5ccdd2f3b342ae8565cd1c8b1 624 SUPERFAMILY SSF52540 12 219 1.28E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_17895 32bf47a5ccdd2f3b342ae8565cd1c8b1 624 SUPERFAMILY SSF50447 228 315 1.26E-19 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSH58p_17895 32bf47a5ccdd2f3b342ae8565cd1c8b1 624 Gene3D G3DSA:2.40.30.10 229 315 2.5E-18 T 14-10-2018 TSH58p_17895 32bf47a5ccdd2f3b342ae8565cd1c8b1 624 Pfam PF01583 Adenylylsulphate kinase 449 603 6.9E-71 T 14-10-2018 TSH58p_17895 32bf47a5ccdd2f3b342ae8565cd1c8b1 624 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 14 420 1.4E-190 T 14-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 TSH58p_17895 32bf47a5ccdd2f3b342ae8565cd1c8b1 624 PRINTS PR00315 GTP-binding elongation factor signature 96 106 2.0E-10 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_17895 32bf47a5ccdd2f3b342ae8565cd1c8b1 624 PRINTS PR00315 GTP-binding elongation factor signature 149 158 2.0E-10 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_17895 32bf47a5ccdd2f3b342ae8565cd1c8b1 624 PRINTS PR00315 GTP-binding elongation factor signature 112 123 2.0E-10 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_17895 32bf47a5ccdd2f3b342ae8565cd1c8b1 624 PRINTS PR00315 GTP-binding elongation factor signature 76 84 2.0E-10 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_17895 32bf47a5ccdd2f3b342ae8565cd1c8b1 624 PRINTS PR00315 GTP-binding elongation factor signature 15 28 2.0E-10 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_17895 32bf47a5ccdd2f3b342ae8565cd1c8b1 624 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 448 620 40.239 T 14-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 TSH58p_17895 32bf47a5ccdd2f3b342ae8565cd1c8b1 624 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 436 616 4.9E-73 T 14-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 TSH58p_17895 32bf47a5ccdd2f3b342ae8565cd1c8b1 624 Gene3D G3DSA:3.40.50.300 427 622 7.6E-74 T 14-10-2018 TSH58p_17895 32bf47a5ccdd2f3b342ae8565cd1c8b1 624 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 69 84 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site TSH58p_17895 32bf47a5ccdd2f3b342ae8565cd1c8b1 624 Gene3D G3DSA:3.40.50.300 5 225 1.1E-60 T 14-10-2018 TSH58p_17895 32bf47a5ccdd2f3b342ae8565cd1c8b1 624 Pfam PF00009 Elongation factor Tu GTP binding domain 13 198 7.4E-37 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_13390 6de59f5487b615673ca2290a9728349f 1066 SMART SM00481 5 72 4.4E-14 T 14-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal TSH58p_13390 6de59f5487b615673ca2290a9728349f 1066 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 274 696 9.5E-149 T 14-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSH58p_13390 6de59f5487b615673ca2290a9728349f 1066 Pfam PF02811 PHP domain 6 98 5.6E-9 T 14-10-2018 IPR004013 PHP domain GO:0003824 TSH58p_13390 6de59f5487b615673ca2290a9728349f 1066 Pfam PF14579 Helix-hairpin-helix motif 770 875 1.8E-21 T 14-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSH58p_13390 6de59f5487b615673ca2290a9728349f 1066 Gene3D G3DSA:3.20.20.140 1 251 1.2E-58 T 14-10-2018 TSH58p_13390 6de59f5487b615673ca2290a9728349f 1066 SUPERFAMILY SSF89550 12 186 2.16E-7 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TSH58p_13390 6de59f5487b615673ca2290a9728349f 1066 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 5 880 6.6E-153 T 14-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSH58p_13390 6de59f5487b615673ca2290a9728349f 1066 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 4 1066 13.962 T 14-10-2018 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSH58p_09770 13eb5f8218568fa9a3a416dc7cadddfe 378 SUPERFAMILY SSF51419 15 261 2.13E-65 T 14-10-2018 IPR029066 PLP-binding barrel TSH58p_09770 13eb5f8218568fa9a3a416dc7cadddfe 378 SUPERFAMILY SSF50621 240 378 7.74E-30 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TSH58p_09770 13eb5f8218568fa9a3a416dc7cadddfe 378 Gene3D G3DSA:2.40.37.10 13 370 2.8E-95 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TSH58p_09770 13eb5f8218568fa9a3a416dc7cadddfe 378 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 44 62 2.2E-17 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TSH58p_09770 13eb5f8218568fa9a3a416dc7cadddfe 378 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 249 268 2.2E-17 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TSH58p_09770 13eb5f8218568fa9a3a416dc7cadddfe 378 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 64 76 2.2E-17 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TSH58p_09770 13eb5f8218568fa9a3a416dc7cadddfe 378 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 166 179 2.2E-17 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TSH58p_09770 13eb5f8218568fa9a3a416dc7cadddfe 378 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 25 258 1.5E-57 T 14-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 TSH58p_09770 13eb5f8218568fa9a3a416dc7cadddfe 378 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 204 217 - T 14-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site TSH58p_09770 13eb5f8218568fa9a3a416dc7cadddfe 378 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 259 356 6.8E-13 T 14-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 TSH58p_09770 13eb5f8218568fa9a3a416dc7cadddfe 378 PRINTS PR01182 Ornithine decarboxylase signature 86 110 4.6E-21 T 14-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 TSH58p_09770 13eb5f8218568fa9a3a416dc7cadddfe 378 PRINTS PR01182 Ornithine decarboxylase signature 42 69 4.6E-21 T 14-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 TSH58p_09770 13eb5f8218568fa9a3a416dc7cadddfe 378 PRINTS PR01182 Ornithine decarboxylase signature 116 138 4.6E-21 T 14-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 TSH58p_09770 13eb5f8218568fa9a3a416dc7cadddfe 378 PRINTS PR01182 Ornithine decarboxylase signature 16 40 4.6E-21 T 14-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 TSH58p_09770 13eb5f8218568fa9a3a416dc7cadddfe 378 PRINTS PR01182 Ornithine decarboxylase signature 320 330 4.6E-21 T 14-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 TSH58p_09770 13eb5f8218568fa9a3a416dc7cadddfe 378 Gene3D G3DSA:3.20.20.10 24 259 2.8E-95 T 14-10-2018 IPR029066 PLP-binding barrel TSH58p_09770 13eb5f8218568fa9a3a416dc7cadddfe 378 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 44 62 - T 14-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site TSH58p_19525 fe6f9d72437c982c2c3b584e02d1b80b 271 Gene3D G3DSA:3.40.50.1820 8 263 2.6E-69 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_19525 fe6f9d72437c982c2c3b584e02d1b80b 271 SUPERFAMILY SSF53474 12 268 4.3E-48 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_19525 fe6f9d72437c982c2c3b584e02d1b80b 271 ProSitePatterns PS00560 Serine carboxypeptidases, histidine active site. 239 256 - T 14-10-2018 IPR033124 Serine carboxypeptidases, histidine active site Reactome: R-HSA-1660662|Reactome: R-HSA-2132295|Reactome: R-HSA-4085001|Reactome: R-HSA-6798695 TSH58p_19525 fe6f9d72437c982c2c3b584e02d1b80b 271 Pfam PF12697 Alpha/beta hydrolase family 33 261 3.2E-18 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_25785 de28f2013654fdffe45e0dbd51abdd8e 255 Gene3D G3DSA:3.40.50.720 1 255 1.3E-78 T 14-10-2018 TSH58p_25785 de28f2013654fdffe45e0dbd51abdd8e 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 252 5.2E-66 T 14-10-2018 TSH58p_25785 de28f2013654fdffe45e0dbd51abdd8e 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.9E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_25785 de28f2013654fdffe45e0dbd51abdd8e 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.9E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_25785 de28f2013654fdffe45e0dbd51abdd8e 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 2.9E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_25785 de28f2013654fdffe45e0dbd51abdd8e 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 2.9E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_25785 de28f2013654fdffe45e0dbd51abdd8e 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 2.9E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_25785 de28f2013654fdffe45e0dbd51abdd8e 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 2.9E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_25785 de28f2013654fdffe45e0dbd51abdd8e 255 SUPERFAMILY SSF51735 5 254 8.23E-83 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_25785 de28f2013654fdffe45e0dbd51abdd8e 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.1E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_25785 de28f2013654fdffe45e0dbd51abdd8e 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 1.1E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_25785 de28f2013654fdffe45e0dbd51abdd8e 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.1E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30625 b6afd5187ec0ad339d37c29628d4226c 375 Gene3D G3DSA:2.60.120.330 8 329 1.0E-78 T 14-10-2018 IPR027443 Isopenicillin N synthase-like TSH58p_30625 b6afd5187ec0ad339d37c29628d4226c 375 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 196 296 2.1E-17 T 14-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 TSH58p_30625 b6afd5187ec0ad339d37c29628d4226c 375 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 20 143 2.2E-32 T 14-10-2018 IPR026992 Non-haem dioxygenase N-terminal domain TSH58p_30625 b6afd5187ec0ad339d37c29628d4226c 375 SUPERFAMILY SSF51197 10 308 1.85E-79 T 14-10-2018 TSH58p_30625 b6afd5187ec0ad339d37c29628d4226c 375 PRINTS PR00682 Isopenicillin N synthase signature 257 283 3.8E-14 T 14-10-2018 TSH58p_30625 b6afd5187ec0ad339d37c29628d4226c 375 PRINTS PR00682 Isopenicillin N synthase signature 222 243 3.8E-14 T 14-10-2018 TSH58p_30625 b6afd5187ec0ad339d37c29628d4226c 375 PRINTS PR00682 Isopenicillin N synthase signature 42 59 3.8E-14 T 14-10-2018 TSH58p_30625 b6afd5187ec0ad339d37c29628d4226c 375 PRINTS PR00682 Isopenicillin N synthase signature 165 181 3.8E-14 T 14-10-2018 TSH58p_07655 107596a89bf51ec7faeaea0caa8e07d5 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 4.4E-12 T 14-10-2018 TSH58p_07655 107596a89bf51ec7faeaea0caa8e07d5 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 4.4E-12 T 14-10-2018 TSH58p_07655 107596a89bf51ec7faeaea0caa8e07d5 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 4.4E-12 T 14-10-2018 TSH58p_07655 107596a89bf51ec7faeaea0caa8e07d5 402 Gene3D G3DSA:3.50.50.100 1 389 6.7E-80 T 14-10-2018 TSH58p_07655 107596a89bf51ec7faeaea0caa8e07d5 402 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 312 3.8E-41 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSH58p_07655 107596a89bf51ec7faeaea0caa8e07d5 402 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 4 26 8.2E-8 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_07655 107596a89bf51ec7faeaea0caa8e07d5 402 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 282 300 8.2E-8 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_07655 107596a89bf51ec7faeaea0caa8e07d5 402 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 152 176 8.2E-8 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_07655 107596a89bf51ec7faeaea0caa8e07d5 402 SUPERFAMILY SSF51905 1 329 6.32E-31 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_13965 ffb3fcb294001fdb9e4d570fdcb77d94 283 Gene3D G3DSA:3.40.50.620 1 280 4.5E-91 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_13965 ffb3fcb294001fdb9e4d570fdcb77d94 283 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 4 268 7.6E-51 T 14-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 TSH58p_13965 ffb3fcb294001fdb9e4d570fdcb77d94 283 SUPERFAMILY SSF52374 4 277 1.43E-85 T 14-10-2018 TSH58p_13965 ffb3fcb294001fdb9e4d570fdcb77d94 283 PRINTS PR00987 Glutamyl-tRNA synthetase signature 192 202 6.7E-17 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSH58p_13965 ffb3fcb294001fdb9e4d570fdcb77d94 283 PRINTS PR00987 Glutamyl-tRNA synthetase signature 208 216 6.7E-17 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSH58p_13965 ffb3fcb294001fdb9e4d570fdcb77d94 283 PRINTS PR00987 Glutamyl-tRNA synthetase signature 21 32 6.7E-17 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSH58p_13965 ffb3fcb294001fdb9e4d570fdcb77d94 283 PRINTS PR00987 Glutamyl-tRNA synthetase signature 7 19 6.7E-17 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSH58p_13965 ffb3fcb294001fdb9e4d570fdcb77d94 283 PRINTS PR00987 Glutamyl-tRNA synthetase signature 36 49 6.7E-17 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSH58p_13965 ffb3fcb294001fdb9e4d570fdcb77d94 283 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 21 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_14930 c5fdb4c7489e8ed76822838cb0377547 287 SUPERFAMILY SSF51658 1 268 1.7E-52 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily TSH58p_14930 c5fdb4c7489e8ed76822838cb0377547 287 Gene3D G3DSA:3.20.20.150 7 287 1.2E-67 T 14-10-2018 TSH58p_14930 c5fdb4c7489e8ed76822838cb0377547 287 Pfam PF01261 Xylose isomerase-like TIM barrel 28 240 1.8E-29 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TSH58p_14455 0af0bee7a0cb105fba6091d6d5c3f705 338 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 95 109 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site TSH58p_14455 0af0bee7a0cb105fba6091d6d5c3f705 338 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 217 229 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site TSH58p_14455 0af0bee7a0cb105fba6091d6d5c3f705 338 Pfam PF00348 Polyprenyl synthetase 46 290 1.4E-72 T 14-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 TSH58p_14455 0af0bee7a0cb105fba6091d6d5c3f705 338 SUPERFAMILY SSF48576 15 337 1.16E-97 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily TSH58p_14455 0af0bee7a0cb105fba6091d6d5c3f705 338 Gene3D G3DSA:1.10.600.10 9 337 4.3E-110 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily TSH58p_11375 a8ba434430401ab7409fe6755f5b5848 236 SUPERFAMILY SSF53335 56 228 4.53E-23 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_11375 a8ba434430401ab7409fe6755f5b5848 236 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 14 233 24.592 T 14-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 TSH58p_11375 a8ba434430401ab7409fe6755f5b5848 236 Gene3D G3DSA:3.40.50.150 22 235 1.3E-49 T 14-10-2018 TSH58p_11375 a8ba434430401ab7409fe6755f5b5848 236 Pfam PF02390 Putative methyltransferase 60 224 1.1E-32 T 14-10-2018 TSH58p_31910 65b291ca645a69bbe633aa2652835302 255 Pfam PF00005 ABC transporter 22 161 9.6E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_31910 65b291ca645a69bbe633aa2652835302 255 SUPERFAMILY SSF52540 4 228 2.46E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_31910 65b291ca645a69bbe633aa2652835302 255 SMART SM00382 31 212 6.8E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_31910 65b291ca645a69bbe633aa2652835302 255 Gene3D G3DSA:3.40.50.300 2 253 5.2E-67 T 14-10-2018 TSH58p_31910 65b291ca645a69bbe633aa2652835302 255 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_12220 7ac3b4b7258166d10304e45088d8658c 1158 TIGRFAM TIGR02784 addA_alphas: double-strand break repair helicase AddA 18 1156 0.0 T 14-10-2018 IPR014151 DNA helicase, AddA type TSH58p_12220 7ac3b4b7258166d10304e45088d8658c 1158 SUPERFAMILY SSF52540 16 897 3.63E-100 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_12220 7ac3b4b7258166d10304e45088d8658c 1158 Gene3D G3DSA:3.40.50.300 356 517 5.7E-28 T 14-10-2018 TSH58p_12220 7ac3b4b7258166d10304e45088d8658c 1158 Pfam PF00580 UvrD/REP helicase N-terminal domain 26 481 4.8E-49 T 14-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 TSH58p_12220 7ac3b4b7258166d10304e45088d8658c 1158 SUPERFAMILY SSF52980 1006 1136 1.55E-7 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TSH58p_12220 7ac3b4b7258166d10304e45088d8658c 1158 Gene3D G3DSA:3.40.50.300 577 680 1.4E-11 T 14-10-2018 TSH58p_12220 7ac3b4b7258166d10304e45088d8658c 1158 Pfam PF13361 UvrD-like helicase C-terminal domain 771 893 8.8E-14 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TSH58p_12220 7ac3b4b7258166d10304e45088d8658c 1158 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1003 1140 1.4E-11 T 14-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type TSH58p_12220 7ac3b4b7258166d10304e45088d8658c 1158 Gene3D G3DSA:3.40.50.300 757 906 9.9E-22 T 14-10-2018 TSH58p_12220 7ac3b4b7258166d10304e45088d8658c 1158 Gene3D G3DSA:3.90.320.10 972 1154 6.5E-7 T 14-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal TSH58p_30350 3f753bce5b42c601804e94002cd006f0 455 TIGRFAM TIGR04247 NosD_copper_fam: nitrous oxide reductase family maturation protein NosD 35 438 9.1E-151 T 14-10-2018 IPR026464 Nitrous oxide reductase family maturation protein NosD TSH58p_30350 3f753bce5b42c601804e94002cd006f0 455 SMART SM00722 40 188 1.0E-10 T 14-10-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain TSH58p_30350 3f753bce5b42c601804e94002cd006f0 455 SMART SM00722 194 386 1.6E-20 T 14-10-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain TSH58p_30350 3f753bce5b42c601804e94002cd006f0 455 Pfam PF05048 Periplasmic copper-binding protein (NosD) 150 402 2.0E-58 T 14-10-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 TSH58p_30350 3f753bce5b42c601804e94002cd006f0 455 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 306 348 7.2E-5 T 14-10-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 TSH58p_30350 3f753bce5b42c601804e94002cd006f0 455 SMART SM00710 190 211 4800.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_30350 3f753bce5b42c601804e94002cd006f0 455 SMART SM00710 212 233 2900.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_30350 3f753bce5b42c601804e94002cd006f0 455 SMART SM00710 311 332 310.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_30350 3f753bce5b42c601804e94002cd006f0 455 SMART SM00710 234 256 190.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_30350 3f753bce5b42c601804e94002cd006f0 455 SMART SM00710 138 167 2600.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_30350 3f753bce5b42c601804e94002cd006f0 455 SMART SM00710 334 380 1400.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_30350 3f753bce5b42c601804e94002cd006f0 455 SMART SM00710 86 114 100.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_30350 3f753bce5b42c601804e94002cd006f0 455 SMART SM00710 116 137 2.8 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_30350 3f753bce5b42c601804e94002cd006f0 455 SMART SM00710 168 189 480.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_30350 3f753bce5b42c601804e94002cd006f0 455 SUPERFAMILY SSF51126 33 428 1.67E-71 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor TSH58p_30350 3f753bce5b42c601804e94002cd006f0 455 Gene3D G3DSA:2.160.20.10 32 277 1.1E-22 T 14-10-2018 IPR012334 Pectin lyase fold TSH58p_28785 c3e7ffe6a40fcd3800045414f0af188b 216 TIGRFAM TIGR02081 metW: methionine biosynthesis protein MetW 20 213 8.7E-76 T 14-10-2018 IPR010743 Methionine biosynthesis MetW KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 TSH58p_28785 c3e7ffe6a40fcd3800045414f0af188b 216 SUPERFAMILY SSF53335 22 185 2.15E-29 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_28785 c3e7ffe6a40fcd3800045414f0af188b 216 Pfam PF07021 Methionine biosynthesis protein MetW 20 213 2.1E-80 T 14-10-2018 IPR010743 Methionine biosynthesis MetW KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 TSH58p_28785 c3e7ffe6a40fcd3800045414f0af188b 216 Gene3D G3DSA:3.40.50.150 22 190 4.5E-26 T 14-10-2018 TSH58p_25440 e7fd281d16c8895ed89bec2a44488071 360 SUPERFAMILY SSF50199 312 359 1.01E-5 T 14-10-2018 TSH58p_11020 554e4c829ea0c672d1fc199b872405f9 443 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 9 443 3.1E-88 T 14-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 TSH58p_11020 554e4c829ea0c672d1fc199b872405f9 443 SUPERFAMILY SSF116878 121 443 4.58E-47 T 14-10-2018 TSH58p_11020 554e4c829ea0c672d1fc199b872405f9 443 Gene3D G3DSA:1.20.120.430 122 443 7.3E-106 T 14-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 TSH58p_11020 554e4c829ea0c672d1fc199b872405f9 443 Pfam PF01926 50S ribosome-binding GTPase 218 330 3.1E-22 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 TSH58p_11020 554e4c829ea0c672d1fc199b872405f9 443 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 3 443 32.013 T 14-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 TSH58p_11020 554e4c829ea0c672d1fc199b872405f9 443 Gene3D G3DSA:3.40.50.300 217 375 7.3E-106 T 14-10-2018 TSH58p_11020 554e4c829ea0c672d1fc199b872405f9 443 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 218 340 7.0E-18 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSH58p_11020 554e4c829ea0c672d1fc199b872405f9 443 Pfam PF10396 GTP-binding protein TrmE N-terminus 4 120 5.9E-38 T 14-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 TSH58p_11020 554e4c829ea0c672d1fc199b872405f9 443 SUPERFAMILY SSF52540 72 363 8.76E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_11020 554e4c829ea0c672d1fc199b872405f9 443 Gene3D G3DSA:3.30.1360.120 1 121 1.7E-41 T 14-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 TSH58p_11020 554e4c829ea0c672d1fc199b872405f9 443 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 268 283 2.1E-6 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 TSH58p_11020 554e4c829ea0c672d1fc199b872405f9 443 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 219 239 2.1E-6 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 TSH58p_11020 554e4c829ea0c672d1fc199b872405f9 443 Pfam PF12631 MnmE helical domain 123 440 3.4E-55 T 14-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 TSH58p_06510 5b04370a27f247baf5f8e04affeafcf5 339 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 327 2.8E-133 T 14-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TSH58p_06510 5b04370a27f247baf5f8e04affeafcf5 339 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 329 45.865 T 14-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TSH58p_06510 5b04370a27f247baf5f8e04affeafcf5 339 SUPERFAMILY SSF51735 1 183 3.95E-75 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_06510 5b04370a27f247baf5f8e04affeafcf5 339 Gene3D G3DSA:1.10.3730.40 183 339 2.1E-76 T 14-10-2018 TSH58p_06510 5b04370a27f247baf5f8e04affeafcf5 339 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 184 327 1.3E-68 T 14-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TSH58p_06510 5b04370a27f247baf5f8e04affeafcf5 339 PIRSF PIRSF000116 4 207 1.5E-48 T 14-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TSH58p_06510 5b04370a27f247baf5f8e04affeafcf5 339 PIRSF PIRSF000116 202 332 1.3E-11 T 14-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TSH58p_06510 5b04370a27f247baf5f8e04affeafcf5 339 SUPERFAMILY SSF48179 184 332 9.18E-73 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_06510 5b04370a27f247baf5f8e04affeafcf5 339 Gene3D G3DSA:3.40.50.720 1 182 1.9E-75 T 14-10-2018 TSH58p_06510 5b04370a27f247baf5f8e04affeafcf5 339 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 178 5.0E-74 T 14-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TSH58p_11045 3d5fea7ca1938c0836c963abff779a66 324 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 140 161 - T 14-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 TSH58p_11045 3d5fea7ca1938c0836c963abff779a66 324 SUPERFAMILY SSF51735 114 265 3.2E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_11045 3d5fea7ca1938c0836c963abff779a66 324 SUPERFAMILY SSF50129 3 144 4.41E-39 T 14-10-2018 IPR011032 GroES-like superfamily TSH58p_11045 3d5fea7ca1938c0836c963abff779a66 324 Gene3D G3DSA:3.40.50.720 123 268 1.1E-116 T 14-10-2018 TSH58p_11045 3d5fea7ca1938c0836c963abff779a66 324 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 92 2.2E-10 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TSH58p_11045 3d5fea7ca1938c0836c963abff779a66 324 Pfam PF00107 Zinc-binding dehydrogenase 151 256 1.2E-28 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TSH58p_11045 3d5fea7ca1938c0836c963abff779a66 324 Gene3D G3DSA:3.90.180.10 12 318 1.1E-116 T 14-10-2018 TSH58p_11045 3d5fea7ca1938c0836c963abff779a66 324 SMART SM00829 11 322 1.5E-31 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TSH58p_05880 aa437990958c1c749d8373a70298052b 336 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 57 72 - T 14-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05880 aa437990958c1c749d8373a70298052b 336 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 11 331 25.951 T 14-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05880 aa437990958c1c749d8373a70298052b 336 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 212 225 - T 14-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05880 aa437990958c1c749d8373a70298052b 336 Pfam PF00146 NADH dehydrogenase 18 325 5.3E-133 T 14-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_02690 1fb0c0ca64b44eed4c61a1162699a648 243 Pfam PF00027 Cyclic nucleotide-binding domain 52 135 1.6E-15 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_02690 1fb0c0ca64b44eed4c61a1162699a648 243 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 205 220 1.1E-8 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_02690 1fb0c0ca64b44eed4c61a1162699a648 243 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 189 205 1.1E-8 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_02690 1fb0c0ca64b44eed4c61a1162699a648 243 Gene3D G3DSA:2.60.120.10 48 164 7.8E-41 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_02690 1fb0c0ca64b44eed4c61a1162699a648 243 SUPERFAMILY SSF51206 35 163 7.59E-29 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like TSH58p_02690 1fb0c0ca64b44eed4c61a1162699a648 243 Gene3D G3DSA:1.10.10.10 165 243 7.7E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_02690 1fb0c0ca64b44eed4c61a1162699a648 243 Pfam PF13545 Crp-like helix-turn-helix domain 168 239 5.0E-18 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_02690 1fb0c0ca64b44eed4c61a1162699a648 243 SMART SM00419 183 232 2.2E-11 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_02690 1fb0c0ca64b44eed4c61a1162699a648 243 SUPERFAMILY SSF46785 166 241 1.7E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_02690 1fb0c0ca64b44eed4c61a1162699a648 243 SMART SM00100 33 148 3.2E-17 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_12295 0c2d1397494c3576a60c0f6b589a4038 284 SUPERFAMILY SSF51366 13 257 1.88E-89 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TSH58p_12295 0c2d1397494c3576a60c0f6b589a4038 284 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 58 71 - T 14-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TSH58p_12295 0c2d1397494c3576a60c0f6b589a4038 284 Gene3D G3DSA:3.20.20.70 9 279 2.7E-97 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_12295 0c2d1397494c3576a60c0f6b589a4038 284 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 24 278 35.844 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TSH58p_12295 0c2d1397494c3576a60c0f6b589a4038 284 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 18 260 2.9E-78 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TSH58p_12295 0c2d1397494c3576a60c0f6b589a4038 284 Pfam PF00290 Tryptophan synthase alpha chain 18 252 8.1E-94 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TSH58p_12520 dbbcf798aefa6b63b38215e96c6664ac 88 Pfam PF01313 Bacterial export proteins, family 3 6 77 1.3E-17 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 TSH58p_12520 dbbcf798aefa6b63b38215e96c6664ac 88 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 1.4E-10 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 TSH58p_12520 dbbcf798aefa6b63b38215e96c6664ac 88 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 1.4E-10 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 TSH58p_12520 dbbcf798aefa6b63b38215e96c6664ac 88 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 1.4E-10 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 TSH58p_11505 789542c6418bd96bda1cfdc331bca6cb 243 Pfam PF13189 Cytidylate kinase-like family 34 204 9.3E-35 T 14-10-2018 TSH58p_11680 276d5dced5e22e0e90b9337c9e96ae02 460 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 162 455 2.6E-87 T 14-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 TSH58p_11680 276d5dced5e22e0e90b9337c9e96ae02 460 Pfam PF12501 Phosphate ATP-binding cassette transporter 7 178 2.3E-34 T 14-10-2018 IPR022182 ABC transporter phosphate permease PstC, N-terminal domain GO:0006817 TSH58p_11680 276d5dced5e22e0e90b9337c9e96ae02 460 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 249 450 1.2E-16 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_11680 276d5dced5e22e0e90b9337c9e96ae02 460 Gene3D G3DSA:1.10.3720.10 227 458 1.3E-35 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_11680 276d5dced5e22e0e90b9337c9e96ae02 460 SUPERFAMILY SSF161098 177 451 1.64E-32 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_10940 943974688d085c6634f4cafba29f327a 373 SUPERFAMILY SSF142695 180 351 3.14E-57 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TSH58p_10940 943974688d085c6634f4cafba29f327a 373 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 179 373 38.487 T 14-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TSH58p_10940 943974688d085c6634f4cafba29f327a 373 Pfam PF00925 GTP cyclohydrolase II 183 349 6.2E-59 T 14-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TSH58p_10940 943974688d085c6634f4cafba29f327a 373 SUPERFAMILY SSF55821 6 175 7.33E-13 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily TSH58p_10940 943974688d085c6634f4cafba29f327a 373 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 198 372 1.6E-65 T 14-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TSH58p_10940 943974688d085c6634f4cafba29f327a 373 Gene3D G3DSA:3.40.50.10990 179 352 1.4E-65 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TSH58p_02730 230cccd190717aeaa31aeef280950da0 314 Gene3D G3DSA:3.20.20.70 5 314 1.3E-131 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_02730 230cccd190717aeaa31aeef280950da0 314 Pfam PF05853 beta-keto acid cleavage enzyme 10 306 1.3E-107 T 14-10-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247 TSH58p_10975 b0bc211305767c3fe9755be9d5ecba7a 179 Pfam PF12100 Domain of unknown function (DUF3576) 72 171 4.8E-44 T 14-10-2018 IPR021959 Protein of unknown function DUF3576 TSH58p_12755 eac5fff32c403648226caefb44181733 94 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 14-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 TSH58p_12755 eac5fff32c403648226caefb44181733 94 Gene3D G3DSA:4.10.520.10 1 94 4.6E-34 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 TSH58p_12755 eac5fff32c403648226caefb44181733 94 Pfam PF00216 Bacterial DNA-binding protein 1 91 4.2E-32 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_12755 eac5fff32c403648226caefb44181733 94 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 1 93 2.1E-45 T 14-10-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 TSH58p_12755 eac5fff32c403648226caefb44181733 94 Hamap MF_00381 Integration host factor subunit beta [ihfB]. 1 94 29.493 T 14-10-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 TSH58p_12755 eac5fff32c403648226caefb44181733 94 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 4.6E-18 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_12755 eac5fff32c403648226caefb44181733 94 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 4.6E-18 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_12755 eac5fff32c403648226caefb44181733 94 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 4.6E-18 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_12755 eac5fff32c403648226caefb44181733 94 SMART SM00411 1 91 3.1E-41 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_12755 eac5fff32c403648226caefb44181733 94 SUPERFAMILY SSF47729 1 91 7.51E-31 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 TSH58p_28395 b92bcb8767fc33477e3867edaccb66f8 172 SUPERFAMILY SSF53254 1 170 3.08E-29 T 14-10-2018 IPR029033 Histidine phosphatase superfamily TSH58p_28395 b92bcb8767fc33477e3867edaccb66f8 172 PIRSF PIRSF000709 1 79 0.0013 T 14-10-2018 TSH58p_28395 b92bcb8767fc33477e3867edaccb66f8 172 SMART SM00855 3 117 4.0E-9 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TSH58p_28395 b92bcb8767fc33477e3867edaccb66f8 172 Gene3D G3DSA:3.40.50.1240 1 172 3.1E-44 T 14-10-2018 IPR029033 Histidine phosphatase superfamily TSH58p_28395 b92bcb8767fc33477e3867edaccb66f8 172 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 83 4.1E-12 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TSH58p_24740 e0a4bd8b143a8a199c5eca97b026a4cd 206 PIRSF PIRSF006305 2 204 7.0E-47 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 TSH58p_24740 e0a4bd8b143a8a199c5eca97b026a4cd 206 Pfam PF02545 Maf-like protein 8 199 2.3E-48 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 TSH58p_24740 e0a4bd8b143a8a199c5eca97b026a4cd 206 Hamap MF_00528 Septum formation protein Maf [maf]. 8 205 29.934 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 TSH58p_24740 e0a4bd8b143a8a199c5eca97b026a4cd 206 Gene3D G3DSA:3.90.950.10 7 204 1.4E-57 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TSH58p_24740 e0a4bd8b143a8a199c5eca97b026a4cd 206 SUPERFAMILY SSF52972 6 200 1.05E-54 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TSH58p_24740 e0a4bd8b143a8a199c5eca97b026a4cd 206 TIGRFAM TIGR00172 maf: septum formation protein Maf 7 199 1.0E-40 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 TSH58p_28120 3b179d3275bf6ed7ab84aa6e9317e052 282 Gene3D G3DSA:1.10.3730.20 55 137 2.8E-5 T 14-10-2018 TSH58p_28120 3b179d3275bf6ed7ab84aa6e9317e052 282 SUPERFAMILY SSF103481 179 279 2.29E-12 T 14-10-2018 TSH58p_28120 3b179d3275bf6ed7ab84aa6e9317e052 282 Pfam PF00892 EamA-like transporter family 144 277 5.2E-10 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_28120 3b179d3275bf6ed7ab84aa6e9317e052 282 SUPERFAMILY SSF103481 37 135 1.14E-10 T 14-10-2018 TSH58p_04280 a660290a9fa4054d17cdad16a7f9486c 98 Pfam PF04800 ETC complex I subunit conserved region 2 95 6.5E-36 T 14-10-2018 IPR006885 NADH dehydrogenase ubiquinone Fe-S protein 4, mitochondrial GO:0016651|GO:0022900 TSH58p_04280 a660290a9fa4054d17cdad16a7f9486c 98 Gene3D G3DSA:3.30.160.190 1 78 8.4E-32 T 14-10-2018 IPR038532 NADH dehydrogenase ubiquinone Fe-S protein 4-like superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_11540 e99a7447a654b9683f21439262f47441 86 Gene3D G3DSA:1.20.58.110 1 86 8.9E-28 T 14-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_11540 e99a7447a654b9683f21439262f47441 86 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.51 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_11540 e99a7447a654b9683f21439262f47441 86 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 12 86 2.0E-19 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_11540 e99a7447a654b9683f21439262f47441 86 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 85 7.3E-25 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_11540 e99a7447a654b9683f21439262f47441 86 SUPERFAMILY SSF46992 3 86 9.02E-30 T 14-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_11540 e99a7447a654b9683f21439262f47441 86 Pfam PF01649 Ribosomal protein S20 2 84 2.9E-27 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 PRINTS PR00313 NodO calcium binding signature 277 285 3.8E-6 T 14-10-2018 TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 PRINTS PR00313 NodO calcium binding signature 425 434 3.8E-6 T 14-10-2018 TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 PRINTS PR00313 NodO calcium binding signature 215 223 3.8E-6 T 14-10-2018 TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 PRINTS PR00313 NodO calcium binding signature 74 85 3.8E-6 T 14-10-2018 TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Gene3D G3DSA:2.60.40.10 2404 2490 4.9E-13 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Gene3D G3DSA:2.60.40.10 2308 2394 7.2E-14 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Gene3D G3DSA:2.60.40.10 2500 2587 3.0E-12 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Gene3D G3DSA:2.60.40.10 1447 1534 4.2E-11 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Gene3D G3DSA:2.60.40.10 2596 2682 7.5E-14 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 SUPERFAMILY SSF51120 3203 3377 3.74E-35 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3229 3245 0.22 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3283 3300 0.0019 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 212 222 47.0 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3193 3210 0.014 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3176 3192 3.5 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3266 3282 0.014 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3302 3318 0.13 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3212 3228 0.0023 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3158 3174 0.002 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3142 3155 0.11 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3123 3138 0.04 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Gene3D G3DSA:2.150.10.10 3207 3265 7.5E-12 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Gene3D G3DSA:2.150.10.10 3035 3159 6.7E-9 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 SUPERFAMILY SSF51120 3098 3210 1.27E-23 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3163 3181 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3298 3316 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Gene3D G3DSA:2.60.40.10 2017 2114 5.8E-13 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Gene3D G3DSA:2.60.40.10 2683 2786 1.8E-13 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Gene3D G3DSA:2.60.40.10 2207 2306 2.8E-13 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Gene3D G3DSA:2.60.40.10 1922 2016 9.8E-13 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Gene3D G3DSA:2.60.40.10 1826 1921 9.3E-14 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Gene3D G3DSA:2.60.40.10 1636 1730 2.2E-13 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Gene3D G3DSA:2.60.40.10 1535 1635 2.2E-12 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Gene3D G3DSA:2.60.40.10 2116 2206 1.2E-12 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Gene3D G3DSA:2.60.40.10 1731 1825 1.4E-12 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Pfam PF12245 Bacterial Ig-like domain (group 3) 2184 2210 3.1 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Pfam PF12245 Bacterial Ig-like domain (group 3) 1713 1733 4.5 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Pfam PF12245 Bacterial Ig-like domain (group 3) 2094 2114 4.5 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Pfam PF12245 Bacterial Ig-like domain (group 3) 1617 1637 4.5 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Pfam PF12245 Bacterial Ig-like domain (group 3) 2767 2786 2.3 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Pfam PF12245 Bacterial Ig-like domain (group 3) 1903 1923 4.5 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Pfam PF12245 Bacterial Ig-like domain (group 3) 2574 2594 4.5 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Pfam PF12245 Bacterial Ig-like domain (group 3) 1808 1828 0.012 T 14-10-2018 IPR022038 Bacterial Ig-like domain TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3172 3190 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3280 3298 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Gene3D G3DSA:2.150.10.10 3266 3382 5.1E-23 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Gene3D G3DSA:2.150.10.10 3160 3206 2.1E-12 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Pfam PF13753 Putative flagellar system-associated repeat 580 655 5.4E-10 T 14-10-2018 IPR028059 Putative flagellar system-associated repeat TSH58p_25120 ea137aebde96092f00810aeb31d80bfd 3386 Pfam PF13753 Putative flagellar system-associated repeat 790 865 5.8E-10 T 14-10-2018 IPR028059 Putative flagellar system-associated repeat TSH58p_16960 5aab2d08c8e5383c54c1e1c2ee7d2c9a 461 SUPERFAMILY SSF51569 2 446 5.13E-206 T 14-10-2018 TSH58p_16960 5aab2d08c8e5383c54c1e1c2ee7d2c9a 461 Pfam PF01474 Class-II DAHP synthetase family 5 442 1.2E-206 T 14-10-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 TSH58p_16960 5aab2d08c8e5383c54c1e1c2ee7d2c9a 461 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 5 448 8.5E-224 T 14-10-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 TSH58p_08460 5c4696cf8fd173324504df548e2c3916 650 Pfam PF13432 Tetratricopeptide repeat 486 537 8.6E-5 T 14-10-2018 TSH58p_08460 5c4696cf8fd173324504df548e2c3916 650 SMART SM00028 472 505 0.0011 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_08460 5c4696cf8fd173324504df548e2c3916 650 SMART SM00028 574 607 8.9 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_08460 5c4696cf8fd173324504df548e2c3916 650 SMART SM00028 506 539 23.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_08460 5c4696cf8fd173324504df548e2c3916 650 Gene3D G3DSA:1.25.40.10 353 613 2.8E-30 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_08460 5c4696cf8fd173324504df548e2c3916 650 SUPERFAMILY SSF48452 455 608 1.9E-22 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_04855 9de8e6b482479cb42e3731a106acadfa 107 SMART SM01259 22 93 4.1E-42 T 14-10-2018 IPR011499 Lipid A biosynthesis, N-terminal GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 TSH58p_04855 9de8e6b482479cb42e3731a106acadfa 107 ProDom PD339292 LIPID A SYNTHASE LIPID-A-DISACCHARIDE TRANSFERASE GLYCOSYLTRANSFERASE BIOSYNTHESIS N-TERMINAL BIOSYNTHESIS SYNTHESIS 19 94 2.0E-25 T 14-10-2018 IPR011499 Lipid A biosynthesis, N-terminal GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 TSH58p_04855 9de8e6b482479cb42e3731a106acadfa 107 Pfam PF07578 Lipid A Biosynthesis N-terminal domain 22 92 4.9E-31 T 14-10-2018 IPR011499 Lipid A biosynthesis, N-terminal GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 TSH58p_04855 9de8e6b482479cb42e3731a106acadfa 107 PIRSF PIRSF028440 1 104 1.6E-37 T 14-10-2018 IPR014546 Uncharacterised conserved protein, lipid A biosynthesis TSH58p_29830 42edc47316fc36634354489e281806ad 80 Gene3D G3DSA:3.30.70.920 1 75 1.3E-18 T 14-10-2018 TSH58p_29830 42edc47316fc36634354489e281806ad 80 Pfam PF01037 Lrp/AsnC ligand binding domain 6 77 3.1E-14 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TSH58p_29830 42edc47316fc36634354489e281806ad 80 SUPERFAMILY SSF54909 3 78 1.61E-15 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel TSH58p_21740 9264f7b6b88048b1954c5485fac875b0 302 SUPERFAMILY SSF46785 1 113 2.5E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_21740 9264f7b6b88048b1954c5485fac875b0 302 Gene3D G3DSA:3.40.190.290 92 293 7.4E-41 T 14-10-2018 TSH58p_21740 9264f7b6b88048b1954c5485fac875b0 302 SUPERFAMILY SSF53850 90 294 5.18E-40 T 14-10-2018 TSH58p_21740 9264f7b6b88048b1954c5485fac875b0 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 4.4E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_21740 9264f7b6b88048b1954c5485fac875b0 302 Pfam PF03466 LysR substrate binding domain 89 291 8.1E-37 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_21740 9264f7b6b88048b1954c5485fac875b0 302 Gene3D G3DSA:1.10.10.10 3 90 1.7E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_22985 5df23601cdfc9c5e4a11ed10390b356e 308 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 16 307 8.7E-119 T 14-10-2018 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type TSH58p_22985 5df23601cdfc9c5e4a11ed10390b356e 308 Pfam PF02653 Branched-chain amino acid transport system / permease component 19 294 3.2E-44 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_30380 394cda5d8e3ef79edf782c0da428aaee 450 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 182 238 - T 14-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_30380 394cda5d8e3ef79edf782c0da428aaee 450 SUPERFAMILY SSF81442 3 440 3.14E-96 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_30380 394cda5d8e3ef79edf782c0da428aaee 450 Gene3D G3DSA:1.20.210.10 1 438 2.9E-133 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_30380 394cda5d8e3ef79edf782c0da428aaee 450 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 7 415 5.5E-83 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_07905 548cec712b92d7cc50f9dd7977f53c03 200 Pfam PF02630 SCO1/SenC 30 181 1.9E-50 T 14-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_07905 548cec712b92d7cc50f9dd7977f53c03 200 SUPERFAMILY SSF52833 40 196 1.45E-56 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_07905 548cec712b92d7cc50f9dd7977f53c03 200 Gene3D G3DSA:3.40.30.10 26 199 9.9E-62 T 14-10-2018 TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 Gene3D G3DSA:3.30.450.20 505 621 2.5E-23 T 14-10-2018 TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 SMART SM00388 646 711 2.9E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 Gene3D G3DSA:1.10.287.130 622 709 1.5E-17 T 14-10-2018 TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 Gene3D G3DSA:3.30.565.10 717 867 3.1E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 Pfam PF00512 His Kinase A (phospho-acceptor) domain 646 711 3.9E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 SUPERFAMILY SSF47384 631 711 2.94E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 SMART SM00387 755 866 3.7E-28 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 SUPERFAMILY SSF55785 379 468 6.46E-14 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 Gene3D G3DSA:3.30.450.20 61 201 6.9E-24 T 14-10-2018 TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 Pfam PF00672 HAMP domain 331 379 8.1E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 PRINTS PR00344 Bacterial sensor protein C-terminal signature 809 819 5.0E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 PRINTS PR00344 Bacterial sensor protein C-terminal signature 826 844 5.0E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 PRINTS PR00344 Bacterial sensor protein C-terminal signature 850 863 5.0E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 PRINTS PR00344 Bacterial sensor protein C-terminal signature 791 805 5.0E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 Pfam PF00072 Response regulator receiver domain 889 1001 5.2E-14 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 756 864 4.2E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 Pfam PF13426 PAS domain 529 625 5.7E-8 T 14-10-2018 IPR000014 PAS domain TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 Gene3D G3DSA:3.40.50.2300 885 1007 6.6E-24 T 14-10-2018 TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 SUPERFAMILY SSF158472 330 378 3.53E-7 T 14-10-2018 TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 SMART SM00448 887 1001 6.4E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 SUPERFAMILY SSF55874 701 866 5.5E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 391 479 1.5E-5 T 14-10-2018 IPR000014 PAS domain TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 518 633 1.5E-21 T 14-10-2018 IPR000014 PAS domain TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 SMART SM00304 329 382 9.0E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 Gene3D G3DSA:1.20.1480.50 294 385 7.5E-8 T 14-10-2018 TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 Gene3D G3DSA:3.30.450.20 386 504 1.7E-16 T 14-10-2018 TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 SMART SM00091 518 586 7.9E-8 T 14-10-2018 IPR000014 PAS domain TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 SMART SM00091 392 457 2.7E-10 T 14-10-2018 IPR000014 PAS domain TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 SUPERFAMILY SSF52172 889 1004 1.32E-24 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 Pfam PF02743 Cache domain 64 280 3.0E-13 T 14-10-2018 IPR033479 Double Cache domain 1 TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 SUPERFAMILY SSF55785 529 635 2.09E-21 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_27125 75089bb493cb23790c595be764646e8b 1007 Pfam PF08448 PAS fold 399 508 3.8E-11 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_17475 89463f4516944efb2b9e59d04d38b6e4 81 SUPERFAMILY SSF47413 2 51 2.73E-9 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_17475 89463f4516944efb2b9e59d04d38b6e4 81 Pfam PF01381 Helix-turn-helix 5 48 6.4E-7 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_17475 89463f4516944efb2b9e59d04d38b6e4 81 SMART SM00530 2 57 2.3E-5 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_17475 89463f4516944efb2b9e59d04d38b6e4 81 Gene3D G3DSA:1.10.260.40 2 71 1.1E-9 T 14-10-2018 TSH58p_18665 f0a5f92e3cb5bb00998787989aaa261e 935 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 158 169 - T 14-10-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TSH58p_18665 f0a5f92e3cb5bb00998787989aaa261e 935 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 588 600 - T 14-10-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TSH58p_18665 f0a5f92e3cb5bb00998787989aaa261e 935 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 20 935 19.772 T 14-10-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TSH58p_18665 f0a5f92e3cb5bb00998787989aaa261e 935 Pfam PF00311 Phosphoenolpyruvate carboxylase 154 935 6.6E-296 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TSH58p_18665 f0a5f92e3cb5bb00998787989aaa261e 935 Gene3D G3DSA:1.20.1440.90 297 423 1.5E-11 T 14-10-2018 TSH58p_18665 f0a5f92e3cb5bb00998787989aaa261e 935 SUPERFAMILY SSF51621 28 935 0.0 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSH58p_18665 f0a5f92e3cb5bb00998787989aaa261e 935 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 269 284 2.8E-55 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TSH58p_18665 f0a5f92e3cb5bb00998787989aaa261e 935 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 763 789 2.8E-55 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TSH58p_18665 f0a5f92e3cb5bb00998787989aaa261e 935 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 420 440 2.8E-55 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TSH58p_18665 f0a5f92e3cb5bb00998787989aaa261e 935 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 586 606 2.8E-55 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TSH58p_18665 f0a5f92e3cb5bb00998787989aaa261e 935 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 628 657 2.8E-55 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TSH58p_18665 f0a5f92e3cb5bb00998787989aaa261e 935 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 157 170 2.8E-55 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TSH58p_18665 f0a5f92e3cb5bb00998787989aaa261e 935 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 210 226 2.8E-55 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TSH58p_14965 28944308d37e89a95c7bfbe8922d4d45 563 SMART SM00304 214 267 3.3E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_14965 28944308d37e89a95c7bfbe8922d4d45 563 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 187 3.0E-28 T 14-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain TSH58p_14965 28944308d37e89a95c7bfbe8922d4d45 563 Gene3D G3DSA:1.10.287.950 271 557 1.6E-55 T 14-10-2018 TSH58p_14965 28944308d37e89a95c7bfbe8922d4d45 563 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 367 525 1.6E-31 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_14965 28944308d37e89a95c7bfbe8922d4d45 563 SUPERFAMILY SSF58104 242 556 5.75E-64 T 14-10-2018 TSH58p_14965 28944308d37e89a95c7bfbe8922d4d45 563 Pfam PF00672 HAMP domain 216 262 9.4E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_14965 28944308d37e89a95c7bfbe8922d4d45 563 Gene3D G3DSA:1.20.1480.50 177 270 2.4E-12 T 14-10-2018 TSH58p_14965 28944308d37e89a95c7bfbe8922d4d45 563 SMART SM00283 303 557 5.5E-47 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_14345 aca42334f00d1420da98a84f1a832cc2 498 SUPERFAMILY SSF63418 21 101 2.35E-20 T 14-10-2018 IPR035911 MurE/MurF, N-terminal TSH58p_14345 aca42334f00d1420da98a84f1a832cc2 498 Gene3D G3DSA:3.90.190.20 326 477 1.0E-33 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TSH58p_14345 aca42334f00d1420da98a84f1a832cc2 498 SUPERFAMILY SSF53623 108 320 5.49E-54 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TSH58p_14345 aca42334f00d1420da98a84f1a832cc2 498 Gene3D G3DSA:3.40.1190.10 89 320 8.7E-66 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TSH58p_14345 aca42334f00d1420da98a84f1a832cc2 498 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 33 464 2.3E-116 T 14-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSH58p_14345 aca42334f00d1420da98a84f1a832cc2 498 SUPERFAMILY SSF53244 329 464 1.4E-30 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TSH58p_14345 aca42334f00d1420da98a84f1a832cc2 498 Pfam PF08245 Mur ligase middle domain 113 302 9.7E-49 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 TSH58p_14345 aca42334f00d1420da98a84f1a832cc2 498 Gene3D G3DSA:3.40.1390.10 1 79 8.2E-23 T 14-10-2018 TSH58p_14345 aca42334f00d1420da98a84f1a832cc2 498 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 5 465 32.291 T 14-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSH58p_14345 aca42334f00d1420da98a84f1a832cc2 498 Pfam PF01225 Mur ligase family, catalytic domain 29 74 5.8E-12 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 TSH58p_14345 aca42334f00d1420da98a84f1a832cc2 498 Pfam PF02875 Mur ligase family, glutamate ligase domain 331 408 1.4E-9 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 TSH58p_11040 c90d57e288cab182c22f250905875090 173 SUPERFAMILY SSF53155 13 79 1.55E-14 T 14-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 TSH58p_11040 c90d57e288cab182c22f250905875090 173 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 14 155 37.551 T 14-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 TSH58p_11040 c90d57e288cab182c22f250905875090 173 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 76 155 6.8E-29 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 TSH58p_11040 c90d57e288cab182c22f250905875090 173 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 123 129 - T 14-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 TSH58p_11040 c90d57e288cab182c22f250905875090 173 Gene3D G3DSA:1.10.10.10 70 156 1.4E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_11040 c90d57e288cab182c22f250905875090 173 Gene3D G3DSA:3.30.160.70 12 69 5.1E-11 T 14-10-2018 TSH58p_11040 c90d57e288cab182c22f250905875090 173 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 75 154 1.9E-26 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 TSH58p_11040 c90d57e288cab182c22f250905875090 173 SUPERFAMILY SSF46767 74 155 2.62E-26 T 14-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 TSH58p_27880 70b1cc254046d60ebc95ad9db2a5b41b 542 SUPERFAMILY SSF55874 374 540 2.36E-41 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_27880 70b1cc254046d60ebc95ad9db2a5b41b 542 PRINTS PR00344 Bacterial sensor protein C-terminal signature 528 541 7.0E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_27880 70b1cc254046d60ebc95ad9db2a5b41b 542 PRINTS PR00344 Bacterial sensor protein C-terminal signature 504 522 7.0E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_27880 70b1cc254046d60ebc95ad9db2a5b41b 542 PRINTS PR00344 Bacterial sensor protein C-terminal signature 469 483 7.0E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_27880 70b1cc254046d60ebc95ad9db2a5b41b 542 Gene3D G3DSA:3.30.450.20 178 267 2.5E-16 T 14-10-2018 TSH58p_27880 70b1cc254046d60ebc95ad9db2a5b41b 542 Gene3D G3DSA:1.10.287.130 301 385 2.2E-21 T 14-10-2018 TSH58p_27880 70b1cc254046d60ebc95ad9db2a5b41b 542 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 432 540 2.5E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_27880 70b1cc254046d60ebc95ad9db2a5b41b 542 Gene3D G3DSA:3.30.565.10 386 542 9.9E-41 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_27880 70b1cc254046d60ebc95ad9db2a5b41b 542 SMART SM00387 431 542 1.0E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_27880 70b1cc254046d60ebc95ad9db2a5b41b 542 SUPERFAMILY SSF47384 304 385 2.55E-19 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_27880 70b1cc254046d60ebc95ad9db2a5b41b 542 Pfam PF00512 His Kinase A (phospho-acceptor) domain 318 385 1.6E-18 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_27880 70b1cc254046d60ebc95ad9db2a5b41b 542 SMART SM00388 316 385 6.9E-20 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_27880 70b1cc254046d60ebc95ad9db2a5b41b 542 Gene3D G3DSA:3.30.450.20 34 175 2.2E-18 T 14-10-2018 TSH58p_10485 0068a4f73ae5998d03706cf68669f605 156 PIRSF PIRSF029477 8 156 3.2E-33 T 14-10-2018 IPR016920 Uncharacterised conserved protein UCP029477 TSH58p_10485 0068a4f73ae5998d03706cf68669f605 156 Pfam PF09537 Domain of unknown function (DUF2383) 14 122 3.0E-29 T 14-10-2018 IPR019052 Domain of unknown function DUF2383 TSH58p_10485 0068a4f73ae5998d03706cf68669f605 156 TIGRFAM TIGR02284 TIGR02284: conserved hypothetical protein 14 151 1.0E-32 T 14-10-2018 IPR011971 Conserved hypothetical protein CHP02284 TSH58p_10485 0068a4f73ae5998d03706cf68669f605 156 Gene3D G3DSA:1.20.1260.10 7 154 1.4E-40 T 14-10-2018 IPR012347 Ferritin-like TSH58p_10485 0068a4f73ae5998d03706cf68669f605 156 SUPERFAMILY SSF47240 8 122 3.19E-6 T 14-10-2018 IPR009078 Ferritin-like superfamily TSH58p_21325 c710656f2468974a736ecc7b650062e3 203 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 104 187 4.1E-26 T 14-10-2018 IPR020057 Ribosomal protein L25, beta domain TSH58p_21325 c710656f2468974a736ecc7b650062e3 203 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 7 97 3.0E-24 T 14-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 TSH58p_21325 c710656f2468974a736ecc7b650062e3 203 SUPERFAMILY SSF50715 5 194 2.62E-56 T 14-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TSH58p_21325 c710656f2468974a736ecc7b650062e3 203 Pfam PF01386 Ribosomal L25p family 7 94 2.3E-26 T 14-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 TSH58p_21325 c710656f2468974a736ecc7b650062e3 203 Gene3D G3DSA:2.40.240.10 3 97 1.1E-29 T 14-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TSH58p_21325 c710656f2468974a736ecc7b650062e3 203 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 7 185 7.5E-41 T 14-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 TSH58p_21325 c710656f2468974a736ecc7b650062e3 203 Gene3D G3DSA:2.170.120.20 99 188 6.3E-22 T 14-10-2018 IPR037121 Ribosomal protein L25, C-terminal TSH58p_21325 c710656f2468974a736ecc7b650062e3 203 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 5 186 28.777 T 14-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 TSH58p_14315 6333819131736ab6a3da4159ed704eb8 471 SUPERFAMILY SSF51984 10 95 8.63E-28 T 14-10-2018 TSH58p_14315 6333819131736ab6a3da4159ed704eb8 471 Gene3D G3DSA:3.40.50.720 10 96 2.6E-31 T 14-10-2018 TSH58p_14315 6333819131736ab6a3da4159ed704eb8 471 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 11 459 3.2E-157 T 14-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSH58p_14315 6333819131736ab6a3da4159ed704eb8 471 SUPERFAMILY SSF53623 94 317 1.96E-65 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TSH58p_14315 6333819131736ab6a3da4159ed704eb8 471 SUPERFAMILY SSF53244 318 461 2.56E-47 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TSH58p_14315 6333819131736ab6a3da4159ed704eb8 471 Pfam PF02875 Mur ligase family, glutamate ligase domain 319 404 6.5E-21 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 TSH58p_14315 6333819131736ab6a3da4159ed704eb8 471 Pfam PF08245 Mur ligase middle domain 113 298 7.0E-26 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 TSH58p_14315 6333819131736ab6a3da4159ed704eb8 471 Gene3D G3DSA:3.90.190.20 317 467 2.5E-52 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TSH58p_14315 6333819131736ab6a3da4159ed704eb8 471 Pfam PF01225 Mur ligase family, catalytic domain 10 108 5.9E-29 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 TSH58p_14315 6333819131736ab6a3da4159ed704eb8 471 Gene3D G3DSA:3.40.1190.10 97 316 3.9E-71 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TSH58p_14315 6333819131736ab6a3da4159ed704eb8 471 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 8 466 41.0 T 14-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSH58p_13480 8425be3f95099991c8469fa577508c2b 619 Gene3D G3DSA:3.40.190.10 41 603 1.3E-225 T 14-10-2018 TSH58p_13480 8425be3f95099991c8469fa577508c2b 619 Gene3D G3DSA:3.10.105.10 327 586 1.3E-225 T 14-10-2018 TSH58p_13480 8425be3f95099991c8469fa577508c2b 619 PIRSF PIRSF002741 20 610 6.0E-94 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TSH58p_13480 8425be3f95099991c8469fa577508c2b 619 SUPERFAMILY SSF53850 62 605 1.66E-112 T 14-10-2018 TSH58p_13480 8425be3f95099991c8469fa577508c2b 619 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 112 521 8.6E-75 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain TSH58p_09950 5a6b2941822960a4a46ea8cef09104a6 336 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 9 162 1.1E-44 T 14-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TSH58p_09950 5a6b2941822960a4a46ea8cef09104a6 336 Gene3D G3DSA:3.40.50.720 2 190 2.0E-55 T 14-10-2018 TSH58p_09950 5a6b2941822960a4a46ea8cef09104a6 336 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 191 212 - T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TSH58p_09950 5a6b2941822960a4a46ea8cef09104a6 336 Gene3D G3DSA:1.10.1040.10 192 336 2.7E-46 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSH58p_09950 5a6b2941822960a4a46ea8cef09104a6 336 SUPERFAMILY SSF51735 6 183 6.46E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_09950 5a6b2941822960a4a46ea8cef09104a6 336 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 7 325 36.643 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TSH58p_09950 5a6b2941822960a4a46ea8cef09104a6 336 SUPERFAMILY SSF48179 182 334 2.72E-50 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_09950 5a6b2941822960a4a46ea8cef09104a6 336 PIRSF PIRSF000114 2 335 3.5E-94 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TSH58p_09950 5a6b2941822960a4a46ea8cef09104a6 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 241 258 8.0E-37 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TSH58p_09950 5a6b2941822960a4a46ea8cef09104a6 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 61 88 8.0E-37 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TSH58p_09950 5a6b2941822960a4a46ea8cef09104a6 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 176 200 8.0E-37 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TSH58p_09950 5a6b2941822960a4a46ea8cef09104a6 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 11 28 8.0E-37 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TSH58p_09950 5a6b2941822960a4a46ea8cef09104a6 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 201 225 8.0E-37 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TSH58p_09950 5a6b2941822960a4a46ea8cef09104a6 336 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 136 156 8.0E-37 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TSH58p_09950 5a6b2941822960a4a46ea8cef09104a6 336 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 183 321 1.6E-46 T 14-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TSH58p_09175 fc6bc700b63d2197bad8546c6686d5c5 613 Pfam PF00905 Penicillin binding protein transpeptidase domain 333 605 1.4E-30 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 TSH58p_09175 fc6bc700b63d2197bad8546c6686d5c5 613 Pfam PF00912 Transglycosylase 63 236 3.9E-53 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_09175 fc6bc700b63d2197bad8546c6686d5c5 613 Gene3D G3DSA:1.10.3810.10 54 252 2.0E-60 T 14-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_09175 fc6bc700b63d2197bad8546c6686d5c5 613 Gene3D G3DSA:3.40.710.10 281 612 2.8E-92 T 14-10-2018 TSH58p_09175 fc6bc700b63d2197bad8546c6686d5c5 613 SUPERFAMILY SSF56601 218 611 2.22E-97 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TSH58p_09175 fc6bc700b63d2197bad8546c6686d5c5 613 SUPERFAMILY SSF53955 52 257 8.72E-61 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily TSH58p_16605 35ea905a752b8434e7873ab981e1db88 303 PRINTS PR01021 OMPA domain signature 248 264 4.8E-14 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 TSH58p_16605 35ea905a752b8434e7873ab981e1db88 303 PRINTS PR01021 OMPA domain signature 233 248 4.8E-14 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 TSH58p_16605 35ea905a752b8434e7873ab981e1db88 303 PRINTS PR01021 OMPA domain signature 203 225 4.8E-14 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 TSH58p_16605 35ea905a752b8434e7873ab981e1db88 303 Pfam PF00691 OmpA family 202 295 2.1E-19 T 14-10-2018 IPR006665 OmpA-like domain TSH58p_16605 35ea905a752b8434e7873ab981e1db88 303 ProSitePatterns PS01068 OmpA-like domain. 235 280 - T 14-10-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 TSH58p_16605 35ea905a752b8434e7873ab981e1db88 303 Gene3D G3DSA:3.30.1330.60 187 303 8.8E-29 T 14-10-2018 IPR036737 OmpA-like domain superfamily TSH58p_16605 35ea905a752b8434e7873ab981e1db88 303 SUPERFAMILY SSF103088 197 300 2.35E-29 T 14-10-2018 IPR036737 OmpA-like domain superfamily TSH58p_13870 356d96d1b2d763cd974a505e0898c236 390 Gene3D G3DSA:3.40.50.2300 267 351 3.0E-5 T 14-10-2018 TSH58p_13870 356d96d1b2d763cd974a505e0898c236 390 TIGRFAM TIGR03863 PQQ_ABC_bind: ABC transporter, substrate binding protein, PQQ-dependent alcohol dehydrogenase system 44 389 3.7E-151 T 14-10-2018 IPR022478 ABC transporter, substrate-binding protein, PQQ-dependent alcohol dehydrogenase system TSH58p_13870 356d96d1b2d763cd974a505e0898c236 390 SUPERFAMILY SSF53822 49 354 2.69E-29 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_13870 356d96d1b2d763cd974a505e0898c236 390 Pfam PF13458 Periplasmic binding protein 54 208 2.3E-9 T 14-10-2018 IPR028081 Leucine-binding protein domain TSH58p_13870 356d96d1b2d763cd974a505e0898c236 390 Gene3D G3DSA:3.40.50.2300 43 233 6.7E-11 T 14-10-2018 TSH58p_13870 356d96d1b2d763cd974a505e0898c236 390 Gene3D G3DSA:3.40.50.2300 260 355 3.0E-5 T 14-10-2018 TSH58p_20160 90dfbe8a8a91da7075ea662daecc8aaa 164 PIRSF PIRSF006105 2 161 7.3E-51 T 14-10-2018 IPR005591 Nitrate reductase cytochrome c-type subunit NapB TSH58p_20160 90dfbe8a8a91da7075ea662daecc8aaa 164 Pfam PF03892 Nitrate reductase cytochrome c-type subunit (NapB) 37 147 1.3E-45 T 14-10-2018 IPR005591 Nitrate reductase cytochrome c-type subunit NapB TSH58p_20160 90dfbe8a8a91da7075ea662daecc8aaa 164 SUPERFAMILY SSF48695 37 153 8.12E-44 T 14-10-2018 IPR036280 Multiheme cytochrome superfamily TSH58p_20160 90dfbe8a8a91da7075ea662daecc8aaa 164 Gene3D G3DSA:1.10.1130.10 66 133 4.0E-29 T 14-10-2018 TSH58p_04685 db9f6065c61f36bafd6ce802eac7c23d 83 Pfam PF02597 ThiS family 3 83 5.2E-20 T 14-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TSH58p_04685 db9f6065c61f36bafd6ce802eac7c23d 83 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 1 83 5.3E-26 T 14-10-2018 TSH58p_04685 db9f6065c61f36bafd6ce802eac7c23d 83 SUPERFAMILY SSF54285 1 83 1.23E-21 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TSH58p_04685 db9f6065c61f36bafd6ce802eac7c23d 83 Gene3D G3DSA:3.10.20.30 1 83 1.1E-22 T 14-10-2018 IPR012675 Beta-grasp domain superfamily TSH58p_26515 ae8904e308b5259f5f651078e9333855 314 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 283 4.1E-53 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TSH58p_26515 ae8904e308b5259f5f651078e9333855 314 Gene3D G3DSA:3.40.50.720 2 307 4.2E-120 T 14-10-2018 TSH58p_26515 ae8904e308b5259f5f651078e9333855 314 SUPERFAMILY SSF52283 1 124 1.04E-24 T 14-10-2018 TSH58p_26515 ae8904e308b5259f5f651078e9333855 314 Gene3D G3DSA:3.40.50.720 104 299 4.2E-120 T 14-10-2018 TSH58p_26515 ae8904e308b5259f5f651078e9333855 314 SUPERFAMILY SSF51735 105 283 8.57E-52 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_26515 ae8904e308b5259f5f651078e9333855 314 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 18 310 3.1E-13 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 TSH58p_12055 d67c33db19c313e35c5eb4baaf4bbe05 310 SUPERFAMILY SSF103481 57 158 1.96E-16 T 14-10-2018 TSH58p_12055 d67c33db19c313e35c5eb4baaf4bbe05 310 SUPERFAMILY SSF103481 200 296 3.92E-13 T 14-10-2018 TSH58p_12055 d67c33db19c313e35c5eb4baaf4bbe05 310 Pfam PF00892 EamA-like transporter family 24 154 3.2E-15 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_12055 d67c33db19c313e35c5eb4baaf4bbe05 310 Pfam PF00892 EamA-like transporter family 164 292 7.0E-9 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_15585 d6fa6dbd6eb5a88cc3f8af515079e421 106 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 78 4.5E-21 T 14-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain TSH58p_15585 d6fa6dbd6eb5a88cc3f8af515079e421 106 Gene3D G3DSA:3.30.70.100 1 106 1.1E-33 T 14-10-2018 TSH58p_15585 d6fa6dbd6eb5a88cc3f8af515079e421 106 SUPERFAMILY SSF54909 1 102 6.86E-34 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel TSH58p_08615 f81823e225bc3224edc93551176688d9 351 Pfam PF01979 Amidohydrolase family 13 307 1.0E-14 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TSH58p_08615 f81823e225bc3224edc93551176688d9 351 Hamap MF_00219 Dihydroorotase [pyrC]. 4 348 45.734 T 14-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSH58p_08615 f81823e225bc3224edc93551176688d9 351 PIRSF PIRSF001237 2 350 4.2E-134 T 14-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSH58p_08615 f81823e225bc3224edc93551176688d9 351 ProSitePatterns PS00482 Dihydroorotase signature 1. 13 21 - T 14-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSH58p_08615 f81823e225bc3224edc93551176688d9 351 SUPERFAMILY SSF51556 4 346 2.15E-138 T 14-10-2018 IPR032466 Metal-dependent hydrolase TSH58p_08615 f81823e225bc3224edc93551176688d9 351 TIGRFAM TIGR00856 pyrC_dimer: dihydroorotase, homodimeric type 6 346 3.3E-133 T 14-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSH58p_08615 f81823e225bc3224edc93551176688d9 351 Gene3D G3DSA:3.20.20.140 5 348 1.0E-103 T 14-10-2018 TSH58p_08615 f81823e225bc3224edc93551176688d9 351 ProSitePatterns PS00483 Dihydroorotase signature 2. 249 260 - T 14-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSH58p_01930 f408067fdfd20b019839c681f3d71743 307 Pfam PF00535 Glycosyl transferase family 2 7 171 1.6E-21 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_01930 f408067fdfd20b019839c681f3d71743 307 Gene3D G3DSA:3.90.550.10 1 221 5.9E-33 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_01930 f408067fdfd20b019839c681f3d71743 307 SUPERFAMILY SSF53448 3 227 2.57E-38 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_18435 891cb2304a9bb9839d93445c53713e69 415 Pfam PF04577 Protein of unknown function (DUF563) 173 381 3.5E-33 T 14-10-2018 IPR007657 Glycosyltransferase 61 GO:0016757 TSH58p_16265 093ad20964954d31c1d85d0c2fc3a7fe 202 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 8 194 1.8E-26 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase TSH58p_16265 093ad20964954d31c1d85d0c2fc3a7fe 202 Gene3D G3DSA:3.40.50.10420 6 202 2.0E-43 T 14-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily TSH58p_16265 093ad20964954d31c1d85d0c2fc3a7fe 202 SUPERFAMILY SSF100950 8 200 1.38E-41 T 14-10-2018 IPR037171 NagB/RpiA transferase-like TSH58p_16265 093ad20964954d31c1d85d0c2fc3a7fe 202 PIRSF PIRSF006806 4 197 2.9E-26 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase TSH58p_16265 093ad20964954d31c1d85d0c2fc3a7fe 202 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 8 194 1.8E-39 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase TSH58p_12395 fee8f6f51fea1ed5263a23a091f45b37 136 SUPERFAMILY SSF52091 8 133 9.81E-15 T 14-10-2018 IPR036513 STAS domain superfamily TSH58p_12395 fee8f6f51fea1ed5263a23a091f45b37 136 Gene3D G3DSA:3.30.750.24 7 134 1.1E-23 T 14-10-2018 IPR036513 STAS domain superfamily TSH58p_12395 fee8f6f51fea1ed5263a23a091f45b37 136 Pfam PF01740 STAS domain 14 121 1.9E-8 T 14-10-2018 IPR002645 STAS domain TSH58p_11900 302002dda10d66e83f258a660da3a267 66 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 14-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_11900 302002dda10d66e83f258a660da3a267 66 Gene3D G3DSA:2.40.50.530 1 64 3.5E-21 T 14-10-2018 TSH58p_11900 302002dda10d66e83f258a660da3a267 66 Pfam PF01632 Ribosomal protein L35 2 59 7.7E-22 T 14-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_11900 302002dda10d66e83f258a660da3a267 66 SUPERFAMILY SSF143034 2 60 1.2E-19 T 14-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_11900 302002dda10d66e83f258a660da3a267 66 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 59 1.6E-20 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TSH58p_11900 302002dda10d66e83f258a660da3a267 66 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 15.889 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TSH58p_11900 302002dda10d66e83f258a660da3a267 66 PRINTS PR00064 Ribosomal protein L35 signature 3 20 3.5E-14 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TSH58p_11900 302002dda10d66e83f258a660da3a267 66 PRINTS PR00064 Ribosomal protein L35 signature 21 35 3.5E-14 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TSH58p_11900 302002dda10d66e83f258a660da3a267 66 PRINTS PR00064 Ribosomal protein L35 signature 36 54 3.5E-14 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TSH58p_20100 ecb8ede0d9f7f7dea4d62db9c69e1f35 402 Hamap MF_02091 Uncharacterized MFS-type transporter YfcJ [yfcJ]. 18 396 37.305 T 14-10-2018 IPR037541 Uncharacterized MFS-type transporter YfcJ TSH58p_20100 ecb8ede0d9f7f7dea4d62db9c69e1f35 402 Gene3D G3DSA:1.20.1250.20 12 391 2.4E-41 T 14-10-2018 TSH58p_20100 ecb8ede0d9f7f7dea4d62db9c69e1f35 402 Pfam PF07690 Major Facilitator Superfamily 233 395 3.0E-16 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_20100 ecb8ede0d9f7f7dea4d62db9c69e1f35 402 SUPERFAMILY SSF103473 18 393 1.02E-49 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_28115 c564005fe2100d821a2cc438c7d5745b 271 SUPERFAMILY SSF53335 70 240 2.43E-42 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_28115 c564005fe2100d821a2cc438c7d5745b 271 Pfam PF05050 Methyltransferase FkbM domain 76 226 8.9E-18 T 14-10-2018 IPR006342 Methyltransferase FkbM TSH58p_28115 c564005fe2100d821a2cc438c7d5745b 271 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 73 209 7.6E-27 T 14-10-2018 IPR006342 Methyltransferase FkbM TSH58p_28115 c564005fe2100d821a2cc438c7d5745b 271 Gene3D G3DSA:3.40.50.150 66 224 7.7E-34 T 14-10-2018 TSH58p_29460 f727a84a83cd884112fd22277db0bec7 288 Pfam PF13609 Gram-negative porin 64 271 1.1E-13 T 14-10-2018 TSH58p_29460 f727a84a83cd884112fd22277db0bec7 288 SUPERFAMILY SSF56935 64 288 3.21E-14 T 14-10-2018 TSH58p_29460 f727a84a83cd884112fd22277db0bec7 288 Gene3D G3DSA:2.40.160.10 34 288 1.3E-13 T 14-10-2018 IPR023614 Porin domain superfamily TSH58p_08950 6a8c0bfac161ebacd3cdab9b6c518a5e 163 Gene3D G3DSA:1.20.120.450 1 160 2.1E-46 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TSH58p_08950 6a8c0bfac161ebacd3cdab9b6c518a5e 163 SUPERFAMILY SSF109854 4 145 1.16E-37 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TSH58p_08950 6a8c0bfac161ebacd3cdab9b6c518a5e 163 Pfam PF05163 DinB family 1 158 2.6E-35 T 14-10-2018 IPR007837 DNA damage-inducible protein DinB TSH58p_21895 ebab4ae698e13dcd9657ee814c7c0e82 347 Gene3D G3DSA:1.20.120.20 128 255 7.5E-6 T 14-10-2018 TSH58p_30825 cac4393569ff56615860e04bc10115e3 214 Gene3D G3DSA:3.40.50.300 3 207 1.9E-31 T 14-10-2018 TSH58p_30825 cac4393569ff56615860e04bc10115e3 214 SUPERFAMILY SSF52540 1 209 8.05E-26 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_30825 cac4393569ff56615860e04bc10115e3 214 Pfam PF07015 VirC1 protein 3 146 1.4E-12 T 14-10-2018 IPR009744 VirC1 TSH58p_19000 ede660fd9a987b7e25e60bc984d5fcbe 760 Pfam PF02901 Pyruvate formate lyase-like 34 619 7.7E-198 T 14-10-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 TSH58p_19000 ede660fd9a987b7e25e60bc984d5fcbe 760 Gene3D G3DSA:3.20.70.20 12 759 1.3E-290 T 14-10-2018 TSH58p_19000 ede660fd9a987b7e25e60bc984d5fcbe 760 PIRSF PIRSF000379 17 760 0.0 T 14-10-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 TSH58p_19000 ede660fd9a987b7e25e60bc984d5fcbe 760 Pfam PF01228 Glycine radical 635 741 2.0E-43 T 14-10-2018 IPR001150 Glycine radical domain GO:0003824 TSH58p_19000 ede660fd9a987b7e25e60bc984d5fcbe 760 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 21 757 0.0 T 14-10-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 TSH58p_19000 ede660fd9a987b7e25e60bc984d5fcbe 760 SUPERFAMILY SSF51998 15 758 1.05E-277 T 14-10-2018 TSH58p_19000 ede660fd9a987b7e25e60bc984d5fcbe 760 ProSitePatterns PS00850 Glycine radical domain signature. 730 738 - T 14-10-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site TSH58p_27325 4e3a26f6b579387d235e599db3145264 539 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_27325 4e3a26f6b579387d235e599db3145264 539 SUPERFAMILY SSF52540 2 241 1.75E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_27325 4e3a26f6b579387d235e599db3145264 539 Gene3D G3DSA:3.40.50.300 288 536 1.6E-60 T 14-10-2018 TSH58p_27325 4e3a26f6b579387d235e599db3145264 539 Pfam PF00005 ABC transporter 341 471 2.0E-20 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_27325 4e3a26f6b579387d235e599db3145264 539 Pfam PF00005 ABC transporter 21 190 2.3E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_27325 4e3a26f6b579387d235e599db3145264 539 SMART SM00382 349 516 3.0E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_27325 4e3a26f6b579387d235e599db3145264 539 SMART SM00382 26 235 1.6E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_27325 4e3a26f6b579387d235e599db3145264 539 Gene3D G3DSA:3.40.50.300 2 284 4.4E-62 T 14-10-2018 TSH58p_27325 4e3a26f6b579387d235e599db3145264 539 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_27325 4e3a26f6b579387d235e599db3145264 539 Pfam PF12848 ABC transporter 229 308 1.2E-25 T 14-10-2018 IPR032781 ABC-transporter extension domain TSH58p_27325 4e3a26f6b579387d235e599db3145264 539 SUPERFAMILY SSF52540 303 524 2.97E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_29455 41ebd5865495cbfb3382648ca4e192d9 629 Gene3D G3DSA:1.20.1530.20 5 390 2.7E-14 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily TSH58p_29455 41ebd5865495cbfb3382648ca4e192d9 629 SMART SM01091 487 566 0.0029 T 14-10-2018 IPR005170 Transporter-associated domain TSH58p_29455 41ebd5865495cbfb3382648ca4e192d9 629 Pfam PF00999 Sodium/hydrogen exchanger family 13 387 2.0E-47 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TSH58p_31850 9b09413d8dd49f7d3a39a596ab610cc1 664 Pfam PF13450 NAD(P)-binding Rossmann-like domain 3 74 4.6E-12 T 14-10-2018 TSH58p_31850 9b09413d8dd49f7d3a39a596ab610cc1 664 Gene3D G3DSA:3.50.50.60 1 116 2.8E-5 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_31850 9b09413d8dd49f7d3a39a596ab610cc1 664 SUPERFAMILY SSF51905 1 655 3.11E-15 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_31850 9b09413d8dd49f7d3a39a596ab610cc1 664 Pfam PF01593 Flavin containing amine oxidoreductase 423 653 1.6E-4 T 14-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 420 426 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 SUPERFAMILY SSF81653 220 317 7.19E-23 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 Gene3D G3DSA:2.70.150.20 207 321 1.2E-34 T 14-10-2018 TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 185 716 7.0E-121 T 14-10-2018 TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 SUPERFAMILY SSF81660 429 551 5.23E-24 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 ProSitePatterns PS01229 Hypothetical cof family signature 2. 614 636 - T 14-10-2018 TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 SUPERFAMILY SSF55008 15 84 3.4E-14 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 167 716 3.6E-179 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 SUPERFAMILY SSF81665 169 702 6.93E-15 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 Gene3D G3DSA:3.40.50.1000 399 666 3.0E-84 T 14-10-2018 IPR023214 HAD superfamily TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 PRINTS PR00941 Cadmium-transporting ATPase signature 19 28 2.1E-9 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 PRINTS PR00941 Cadmium-transporting ATPase signature 283 299 2.1E-9 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 PRINTS PR00941 Cadmium-transporting ATPase signature 202 222 2.1E-9 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 PRINTS PR00941 Cadmium-transporting ATPase signature 30 51 2.1E-9 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 PRINTS PR00941 Cadmium-transporting ATPase signature 302 316 2.1E-9 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 267 281 2.8E-30 T 14-10-2018 TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 418 432 2.8E-30 T 14-10-2018 TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 614 633 2.8E-30 T 14-10-2018 TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 541 552 2.8E-30 T 14-10-2018 TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 637 649 2.8E-30 T 14-10-2018 TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 563 573 2.8E-30 T 14-10-2018 TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 Gene3D G3DSA:3.40.1110.10 429 548 3.0E-84 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 SUPERFAMILY SSF56784 416 714 2.38E-51 T 14-10-2018 IPR036412 HAD-like superfamily TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 Gene3D G3DSA:3.30.70.100 14 82 1.1E-12 T 14-10-2018 TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 Pfam PF00403 Heavy-metal-associated domain 19 78 3.4E-7 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 190 700 4.9E-74 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 Pfam PF00122 E1-E2 ATPase 218 398 1.7E-49 T 14-10-2018 TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 167 508 5.1E-96 T 14-10-2018 TSH58p_32180 2324d5dfebfe52aa31b74db60bd2b6cf 728 Pfam PF00702 haloacid dehalogenase-like hydrolase 414 628 2.3E-34 T 14-10-2018 TSH58p_11205 1ee8d01577a828e39ece6f48d06c873c 437 Gene3D G3DSA:1.10.287.950 150 434 4.6E-53 T 14-10-2018 TSH58p_11205 1ee8d01577a828e39ece6f48d06c873c 437 Pfam PF08447 PAS fold 56 142 3.7E-15 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 TSH58p_11205 1ee8d01577a828e39ece6f48d06c873c 437 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 275 302 4.3E-24 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_11205 1ee8d01577a828e39ece6f48d06c873c 437 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 304 333 4.3E-24 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_11205 1ee8d01577a828e39ece6f48d06c873c 437 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 197 226 4.3E-24 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_11205 1ee8d01577a828e39ece6f48d06c873c 437 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 352 381 4.3E-24 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_11205 1ee8d01577a828e39ece6f48d06c873c 437 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 249 404 1.4E-32 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_11205 1ee8d01577a828e39ece6f48d06c873c 437 Gene3D G3DSA:3.30.450.20 19 149 2.6E-18 T 14-10-2018 TSH58p_11205 1ee8d01577a828e39ece6f48d06c873c 437 SMART SM00283 173 431 2.4E-45 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_11205 1ee8d01577a828e39ece6f48d06c873c 437 SUPERFAMILY SSF58104 155 430 7.46E-61 T 14-10-2018 TSH58p_11205 1ee8d01577a828e39ece6f48d06c873c 437 SUPERFAMILY SSF55785 57 152 2.79E-10 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_19440 746f413450ff5716a056465caa9457f9 267 SMART SM00382 37 237 8.2E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_19440 746f413450ff5716a056465caa9457f9 267 Gene3D G3DSA:3.40.50.300 2 264 1.2E-61 T 14-10-2018 TSH58p_19440 746f413450ff5716a056465caa9457f9 267 Pfam PF00005 ABC transporter 30 188 5.7E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_19440 746f413450ff5716a056465caa9457f9 267 SUPERFAMILY SSF52540 11 259 2.96E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_19440 746f413450ff5716a056465caa9457f9 267 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 237 259 6.4E-11 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSH58p_19440 746f413450ff5716a056465caa9457f9 267 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_12340 c4ce3c8b850ef1d413f98f144381cf5a 229 SUPERFAMILY SSF55620 32 220 2.89E-52 T 14-10-2018 TSH58p_12340 c4ce3c8b850ef1d413f98f144381cf5a 229 Pfam PF01227 GTP cyclohydrolase I 41 220 4.1E-46 T 14-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 TSH58p_12340 c4ce3c8b850ef1d413f98f144381cf5a 229 Gene3D G3DSA:1.10.286.10 4 83 1.3E-7 T 14-10-2018 TSH58p_12340 c4ce3c8b850ef1d413f98f144381cf5a 229 Gene3D G3DSA:3.30.1130.10 87 223 3.3E-38 T 14-10-2018 TSH58p_29335 3580ca7fd1b720c969f6212f92cf4f0b 291 SUPERFAMILY SSF88713 13 287 1.0E-68 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TSH58p_29335 3580ca7fd1b720c969f6212f92cf4f0b 291 Gene3D G3DSA:3.20.20.370 14 288 4.4E-43 T 14-10-2018 TSH58p_29335 3580ca7fd1b720c969f6212f92cf4f0b 291 Pfam PF04794 YdjC-like protein 16 276 3.8E-51 T 14-10-2018 IPR006879 Carbohydrate deacetylase YdjC-like TSH58p_11775 9915bfeadcb3c25bc56c2ec883706c25 318 Gene3D G3DSA:3.40.50.1980 171 301 3.1E-44 T 14-10-2018 TSH58p_11775 9915bfeadcb3c25bc56c2ec883706c25 318 PRINTS PR00691 Adhesin B signature 24 45 2.2E-21 T 14-10-2018 IPR006129 Adhesin B GO:0007155 TSH58p_11775 9915bfeadcb3c25bc56c2ec883706c25 318 PRINTS PR00691 Adhesin B signature 124 143 2.2E-21 T 14-10-2018 IPR006129 Adhesin B GO:0007155 TSH58p_11775 9915bfeadcb3c25bc56c2ec883706c25 318 PRINTS PR00691 Adhesin B signature 231 248 2.2E-21 T 14-10-2018 IPR006129 Adhesin B GO:0007155 TSH58p_11775 9915bfeadcb3c25bc56c2ec883706c25 318 PRINTS PR00691 Adhesin B signature 68 87 2.2E-21 T 14-10-2018 IPR006129 Adhesin B GO:0007155 TSH58p_11775 9915bfeadcb3c25bc56c2ec883706c25 318 PRINTS PR00691 Adhesin B signature 49 67 2.2E-21 T 14-10-2018 IPR006129 Adhesin B GO:0007155 TSH58p_11775 9915bfeadcb3c25bc56c2ec883706c25 318 PRINTS PR00691 Adhesin B signature 182 199 2.2E-21 T 14-10-2018 IPR006129 Adhesin B GO:0007155 TSH58p_11775 9915bfeadcb3c25bc56c2ec883706c25 318 Pfam PF01297 Zinc-uptake complex component A periplasmic 27 299 8.8E-69 T 14-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 TSH58p_11775 9915bfeadcb3c25bc56c2ec883706c25 318 PRINTS PR00690 Adhesin family signature 55 68 1.9E-34 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TSH58p_11775 9915bfeadcb3c25bc56c2ec883706c25 318 PRINTS PR00690 Adhesin family signature 68 85 1.9E-34 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TSH58p_11775 9915bfeadcb3c25bc56c2ec883706c25 318 PRINTS PR00690 Adhesin family signature 24 42 1.9E-34 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TSH58p_11775 9915bfeadcb3c25bc56c2ec883706c25 318 PRINTS PR00690 Adhesin family signature 182 203 1.9E-34 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TSH58p_11775 9915bfeadcb3c25bc56c2ec883706c25 318 PRINTS PR00690 Adhesin family signature 235 253 1.9E-34 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TSH58p_11775 9915bfeadcb3c25bc56c2ec883706c25 318 PRINTS PR00690 Adhesin family signature 266 285 1.9E-34 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TSH58p_11775 9915bfeadcb3c25bc56c2ec883706c25 318 Gene3D G3DSA:3.40.50.1980 23 168 5.3E-40 T 14-10-2018 TSH58p_11775 9915bfeadcb3c25bc56c2ec883706c25 318 SUPERFAMILY SSF53807 23 301 3.19E-73 T 14-10-2018 TSH58p_15180 01b9bad153ca4a4eaf2c60ecc7b64b83 275 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 9.9E-127 T 14-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 TSH58p_15180 01b9bad153ca4a4eaf2c60ecc7b64b83 275 Gene3D G3DSA:4.10.950.10 196 274 3.5E-35 T 14-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15180 01b9bad153ca4a4eaf2c60ecc7b64b83 275 Gene3D G3DSA:2.40.50.140 1 114 1.4E-46 T 14-10-2018 TSH58p_15180 01b9bad153ca4a4eaf2c60ecc7b64b83 275 PIRSF PIRSF002158 4 275 3.1E-102 T 14-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15180 01b9bad153ca4a4eaf2c60ecc7b64b83 275 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 250 1.5E-56 T 14-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 TSH58p_15180 01b9bad153ca4a4eaf2c60ecc7b64b83 275 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 1.6E-31 T 14-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15180 01b9bad153ca4a4eaf2c60ecc7b64b83 275 SUPERFAMILY SSF50104 126 272 1.75E-61 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily TSH58p_15180 01b9bad153ca4a4eaf2c60ecc7b64b83 275 Gene3D G3DSA:2.30.30.30 115 195 8.5E-32 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 TSH58p_15180 01b9bad153ca4a4eaf2c60ecc7b64b83 275 SMART SM01382 124 252 1.5E-90 T 14-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 TSH58p_15180 01b9bad153ca4a4eaf2c60ecc7b64b83 275 SMART SM01383 42 118 3.5E-45 T 14-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15180 01b9bad153ca4a4eaf2c60ecc7b64b83 275 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 47.394 T 14-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 TSH58p_15180 01b9bad153ca4a4eaf2c60ecc7b64b83 275 SUPERFAMILY SSF50249 2 125 1.34E-48 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_15180 01b9bad153ca4a4eaf2c60ecc7b64b83 275 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 14-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_32420 cc0b8919bed182be1bb50a008c2a5178 295 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 220 292 1.6E-15 T 14-10-2018 IPR006260 TonB/TolA, C-terminal TSH58p_32420 cc0b8919bed182be1bb50a008c2a5178 295 Gene3D G3DSA:3.30.1150.10 124 294 1.8E-19 T 14-10-2018 TSH58p_32420 cc0b8919bed182be1bb50a008c2a5178 295 SUPERFAMILY SSF74653 201 292 1.83E-14 T 14-10-2018 TSH58p_32420 cc0b8919bed182be1bb50a008c2a5178 295 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 221 291 4.8E-13 T 14-10-2018 IPR037682 TonB, C-terminal GO:0055085 TSH58p_14185 61d371552617b034f5b3fc526e880581 220 SUPERFAMILY SSF52172 2 128 3.98E-25 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_14185 61d371552617b034f5b3fc526e880581 220 Pfam PF00072 Response regulator receiver domain 3 115 1.4E-17 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_14185 61d371552617b034f5b3fc526e880581 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 162 216 4.1E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_14185 61d371552617b034f5b3fc526e880581 220 SMART SM00421 160 217 1.2E-23 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_14185 61d371552617b034f5b3fc526e880581 220 Gene3D G3DSA:3.40.50.12740 1 220 4.2E-50 T 14-10-2018 TSH58p_14185 61d371552617b034f5b3fc526e880581 220 SUPERFAMILY SSF46894 159 218 2.35E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_14185 61d371552617b034f5b3fc526e880581 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 177 1.7E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_14185 61d371552617b034f5b3fc526e880581 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 193 205 1.7E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_14185 61d371552617b034f5b3fc526e880581 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 193 1.7E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_14185 61d371552617b034f5b3fc526e880581 220 SMART SM00448 1 115 1.3E-19 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_27475 4c379581e4675283db6bec2208d922ea 413 Gene3D G3DSA:3.40.50.1100 17 316 9.0E-105 T 14-10-2018 TSH58p_27475 4c379581e4675283db6bec2208d922ea 413 SUPERFAMILY SSF55021 334 402 4.2E-8 T 14-10-2018 TSH58p_27475 4c379581e4675283db6bec2208d922ea 413 Gene3D G3DSA:3.30.70.260 333 408 4.4E-5 T 14-10-2018 TSH58p_27475 4c379581e4675283db6bec2208d922ea 413 Gene3D G3DSA:3.40.50.1100 60 156 9.0E-105 T 14-10-2018 TSH58p_27475 4c379581e4675283db6bec2208d922ea 413 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 31 311 2.8E-73 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TSH58p_27475 4c379581e4675283db6bec2208d922ea 413 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 31 405 1.5E-125 T 14-10-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 TSH58p_27475 4c379581e4675283db6bec2208d922ea 413 SUPERFAMILY SSF53686 13 319 6.29E-88 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TSH58p_03630 fc836df5f92fb652f8b9c8031d882b36 350 TIGRFAM TIGR03830 CxxCG_CxxCG_HTH: putative zinc finger/helix-turn-helix protein, YgiT family 11 127 5.6E-22 T 14-10-2018 IPR022452 Antitoxin MqsA TSH58p_03630 fc836df5f92fb652f8b9c8031d882b36 350 SUPERFAMILY SSF47413 75 128 2.63E-7 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_03630 fc836df5f92fb652f8b9c8031d882b36 350 Gene3D G3DSA:1.10.260.40 23 135 8.3E-19 T 14-10-2018 TSH58p_03630 fc836df5f92fb652f8b9c8031d882b36 350 Pfam PF15731 Antitoxin component of bacterial toxin-antitoxin system, MqsA 11 126 3.0E-8 T 14-10-2018 IPR032758 Antitoxin MqsA/HigA-2 TSH58p_03630 fc836df5f92fb652f8b9c8031d882b36 350 Pfam PF13274 Protein of unknown function (DUF4065) 207 316 1.0E-17 T 14-10-2018 IPR025272 Domain of unknown function DUF4065 TSH58p_03630 fc836df5f92fb652f8b9c8031d882b36 350 SMART SM00530 79 133 0.0012 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_07915 539bb842b6ee67bf16b3842f70c50920 247 Pfam PF00119 ATP synthase A chain 30 240 7.4E-58 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_07915 539bb842b6ee67bf16b3842f70c50920 247 SUPERFAMILY SSF81336 77 240 7.19E-46 T 14-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_07915 539bb842b6ee67bf16b3842f70c50920 247 Hamap MF_01393 ATP synthase subunit a [atpB]. 5 247 16.244 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_07915 539bb842b6ee67bf16b3842f70c50920 247 PRINTS PR00123 ATP synthase A subunit signature 85 101 1.5E-29 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_07915 539bb842b6ee67bf16b3842f70c50920 247 PRINTS PR00123 ATP synthase A subunit signature 166 188 1.5E-29 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_07915 539bb842b6ee67bf16b3842f70c50920 247 PRINTS PR00123 ATP synthase A subunit signature 146 161 1.5E-29 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_07915 539bb842b6ee67bf16b3842f70c50920 247 PRINTS PR00123 ATP synthase A subunit signature 227 242 1.5E-29 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_07915 539bb842b6ee67bf16b3842f70c50920 247 ProSitePatterns PS00449 ATP synthase a subunit signature. 169 178 - T 14-10-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_07915 539bb842b6ee67bf16b3842f70c50920 247 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 4 243 1.4E-67 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_07915 539bb842b6ee67bf16b3842f70c50920 247 Gene3D G3DSA:1.20.120.220 77 247 1.2E-34 T 14-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_28970 284f1178534c8d3fbcddefe630c7769e 321 Pfam PF13379 NMT1-like family 10 253 5.4E-15 T 14-10-2018 TSH58p_28970 284f1178534c8d3fbcddefe630c7769e 321 SUPERFAMILY SSF53850 15 253 3.02E-23 T 14-10-2018 TSH58p_28970 284f1178534c8d3fbcddefe630c7769e 321 Gene3D G3DSA:3.40.190.10 10 115 1.0E-9 T 14-10-2018 TSH58p_28970 284f1178534c8d3fbcddefe630c7769e 321 Gene3D G3DSA:3.40.190.10 126 312 2.1E-14 T 14-10-2018 TSH58p_31320 2e8bfabfcdb89d33b76c3351989a6953 237 SMART SM00382 38 226 8.9E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_31320 2e8bfabfcdb89d33b76c3351989a6953 237 SUPERFAMILY SSF52540 10 230 9.74E-74 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_31320 2e8bfabfcdb89d33b76c3351989a6953 237 Pfam PF00005 ABC transporter 29 177 5.6E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_31320 2e8bfabfcdb89d33b76c3351989a6953 237 Gene3D G3DSA:3.40.50.300 8 236 5.8E-64 T 14-10-2018 TSH58p_31320 2e8bfabfcdb89d33b76c3351989a6953 237 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_19305 1d40d39f5ad71e34de3ffe51f4c39d51 335 Pfam PF01032 FecCD transport family 13 328 1.0E-82 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TSH58p_19305 1d40d39f5ad71e34de3ffe51f4c39d51 335 Gene3D G3DSA:1.10.3470.10 2 334 2.7E-96 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_19305 1d40d39f5ad71e34de3ffe51f4c39d51 335 SUPERFAMILY SSF81345 5 327 9.02E-74 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_13250 67fe707caf76c916a1c41f233d408f0a 258 Gene3D G3DSA:3.40.50.2300 133 238 1.9E-8 T 14-10-2018 TSH58p_13250 67fe707caf76c916a1c41f233d408f0a 258 SUPERFAMILY SSF47226 15 115 2.75E-12 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_13250 67fe707caf76c916a1c41f233d408f0a 258 Pfam PF01627 Hpt domain 14 110 4.8E-11 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TSH58p_13250 67fe707caf76c916a1c41f233d408f0a 258 SUPERFAMILY SSF52172 138 235 5.98E-12 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_13250 67fe707caf76c916a1c41f233d408f0a 258 Gene3D G3DSA:1.20.120.160 8 132 2.7E-10 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_18400 497187d7488e82df17659a7c55fb4644 747 SUPERFAMILY SSF52540 483 726 4.15E-85 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_18400 497187d7488e82df17659a7c55fb4644 747 ProSitePatterns PS00211 ABC transporters family signature. 628 642 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_18400 497187d7488e82df17659a7c55fb4644 747 Gene3D G3DSA:1.20.1560.10 161 476 5.2E-55 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_18400 497187d7488e82df17659a7c55fb4644 747 SUPERFAMILY SSF90123 156 475 5.76E-53 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_18400 497187d7488e82df17659a7c55fb4644 747 Gene3D G3DSA:3.40.50.300 477 730 3.8E-86 T 14-10-2018 TSH58p_18400 497187d7488e82df17659a7c55fb4644 747 Gene3D G3DSA:3.90.70.10 16 148 2.3E-18 T 14-10-2018 TSH58p_18400 497187d7488e82df17659a7c55fb4644 747 Pfam PF00664 ABC transporter transmembrane region 178 436 7.6E-32 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TSH58p_18400 497187d7488e82df17659a7c55fb4644 747 SMART SM00382 516 700 1.9E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_18400 497187d7488e82df17659a7c55fb4644 747 Pfam PF00005 ABC transporter 507 656 2.7E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_29905 bd2c1c09961f5730ace14cff87c96e46 167 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 20 159 1.1E-46 T 14-10-2018 IPR008136 CinA, C-terminal TSH58p_29905 bd2c1c09961f5730ace14cff87c96e46 167 Pfam PF02464 Competence-damaged protein 8 159 1.7E-55 T 14-10-2018 IPR008136 CinA, C-terminal TSH58p_29905 bd2c1c09961f5730ace14cff87c96e46 167 SUPERFAMILY SSF142433 4 159 1.31E-53 T 14-10-2018 IPR036653 CinA-like, C-terminal TSH58p_29905 bd2c1c09961f5730ace14cff87c96e46 167 Gene3D G3DSA:3.90.950.20 1 164 1.4E-59 T 14-10-2018 IPR036653 CinA-like, C-terminal TSH58p_29670 d14307ee449f45d79676366659986239 148 Gene3D G3DSA:3.90.940.10 1 93 2.8E-23 T 14-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TSH58p_29670 d14307ee449f45d79676366659986239 148 SMART SM01409 8 60 1.0E-13 T 14-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TSH58p_29670 d14307ee449f45d79676366659986239 148 Pfam PF01192 RNA polymerase Rpb6 8 58 5.7E-13 T 14-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TSH58p_29670 d14307ee449f45d79676366659986239 148 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 56 5.8E-16 T 14-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_29670 d14307ee449f45d79676366659986239 148 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 61 15.993 T 14-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSH58p_29670 d14307ee449f45d79676366659986239 148 SUPERFAMILY SSF63562 1 81 2.88E-20 T 14-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TSH58p_06880 a1503ef7d8f58dfeb271f29d23fc666a 230 SUPERFAMILY SSF53056 10 229 1.06E-56 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 TSH58p_06880 a1503ef7d8f58dfeb271f29d23fc666a 230 Gene3D G3DSA:3.40.1050.10 3 228 2.9E-70 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 TSH58p_06880 a1503ef7d8f58dfeb271f29d23fc666a 230 SMART SM00947 38 220 1.3E-67 T 14-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 TSH58p_06880 a1503ef7d8f58dfeb271f29d23fc666a 230 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 95 115 - T 14-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 TSH58p_06880 a1503ef7d8f58dfeb271f29d23fc666a 230 Pfam PF00484 Carbonic anhydrase 45 215 2.9E-49 T 14-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 TSH58p_06880 a1503ef7d8f58dfeb271f29d23fc666a 230 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 50 57 - T 14-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 TSH58p_26485 1384ef2f091b9fdd8f456ef1cc7fb642 273 Gene3D G3DSA:3.40.50.150 111 253 2.2E-25 T 14-10-2018 TSH58p_26485 1384ef2f091b9fdd8f456ef1cc7fb642 273 SUPERFAMILY SSF53335 134 235 7.64E-23 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_26485 1384ef2f091b9fdd8f456ef1cc7fb642 273 Pfam PF08241 Methyltransferase domain 134 181 4.0E-16 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TSH58p_14300 cfcfbf2434b5d66c7cc402aac5e14987 315 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 6 311 33.974 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSH58p_14300 cfcfbf2434b5d66c7cc402aac5e14987 315 Pfam PF01820 D-ala D-ala ligase N-terminus 8 90 3.7E-20 T 14-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSH58p_14300 cfcfbf2434b5d66c7cc402aac5e14987 315 SUPERFAMILY SSF56059 102 309 3.16E-45 T 14-10-2018 TSH58p_14300 cfcfbf2434b5d66c7cc402aac5e14987 315 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 7 310 4.5E-78 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSH58p_14300 cfcfbf2434b5d66c7cc402aac5e14987 315 Gene3D G3DSA:3.40.50.20 1 105 1.6E-35 T 14-10-2018 TSH58p_14300 cfcfbf2434b5d66c7cc402aac5e14987 315 Gene3D G3DSA:3.30.1490.20 117 179 1.1E-52 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSH58p_14300 cfcfbf2434b5d66c7cc402aac5e14987 315 Gene3D G3DSA:3.30.470.20 106 303 1.1E-52 T 14-10-2018 TSH58p_14300 cfcfbf2434b5d66c7cc402aac5e14987 315 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 69 80 - T 14-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSH58p_14300 cfcfbf2434b5d66c7cc402aac5e14987 315 PIRSF PIRSF039102 53 315 1.7E-65 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSH58p_14300 cfcfbf2434b5d66c7cc402aac5e14987 315 PIRSF PIRSF039102 3 58 1.5E-11 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSH58p_14300 cfcfbf2434b5d66c7cc402aac5e14987 315 SUPERFAMILY SSF52440 5 102 3.07E-30 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TSH58p_14300 cfcfbf2434b5d66c7cc402aac5e14987 315 Pfam PF07478 D-ala D-ala ligase C-terminus 137 308 5.1E-39 T 14-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSH58p_15630 7bd266991f589ff714d58c28d8fc5ef9 194 Pfam PF03641 Possible lysine decarboxylase 49 178 8.1E-44 T 14-10-2018 IPR031100 LOG family TSH58p_15630 7bd266991f589ff714d58c28d8fc5ef9 194 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 6 179 2.5E-60 T 14-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG TSH58p_15630 7bd266991f589ff714d58c28d8fc5ef9 194 Gene3D G3DSA:3.40.50.450 1 192 8.1E-75 T 14-10-2018 TSH58p_15630 7bd266991f589ff714d58c28d8fc5ef9 194 SUPERFAMILY SSF102405 4 180 1.3E-63 T 14-10-2018 TSH58p_18680 c608a9b73825e619b2a7b23a29ac4880 328 Pfam PF07885 Ion channel 232 312 3.5E-13 T 14-10-2018 IPR013099 Potassium channel domain TSH58p_18680 c608a9b73825e619b2a7b23a29ac4880 328 Gene3D G3DSA:1.10.287.70 221 325 1.0E-16 T 14-10-2018 TSH58p_18680 c608a9b73825e619b2a7b23a29ac4880 328 SUPERFAMILY SSF81324 221 314 3.79E-16 T 14-10-2018 TSH58p_04215 25c43b72979d487cefd2b5d8a8715cbb 312 Gene3D G3DSA:3.40.190.10 111 247 1.8E-96 T 14-10-2018 TSH58p_04215 25c43b72979d487cefd2b5d8a8715cbb 312 Pfam PF16868 NMT1-like family 27 310 4.5E-91 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family TSH58p_04215 25c43b72979d487cefd2b5d8a8715cbb 312 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 6 310 2.1E-113 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family TSH58p_04215 25c43b72979d487cefd2b5d8a8715cbb 312 SUPERFAMILY SSF53850 22 312 7.33E-75 T 14-10-2018 TSH58p_04215 25c43b72979d487cefd2b5d8a8715cbb 312 Gene3D G3DSA:3.40.190.10 27 310 1.8E-96 T 14-10-2018 TSH58p_01355 a65a949388cf41dfe6ff3cbb24f755fe 127 Gene3D G3DSA:3.10.129.10 17 127 1.8E-10 T 14-10-2018 TSH58p_01355 a65a949388cf41dfe6ff3cbb24f755fe 127 SUPERFAMILY SSF54637 4 126 2.83E-11 T 14-10-2018 IPR029069 HotDog domain superfamily TSH58p_06545 15f71b3cea4672a76f14def51336217e 518 Gene3D G3DSA:2.30.42.10 292 398 4.1E-29 T 14-10-2018 TSH58p_06545 15f71b3cea4672a76f14def51336217e 518 SUPERFAMILY SSF50494 54 293 5.38E-67 T 14-10-2018 IPR009003 Peptidase S1, PA clan TSH58p_06545 15f71b3cea4672a76f14def51336217e 518 SMART SM00228 297 379 4.7E-13 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_06545 15f71b3cea4672a76f14def51336217e 518 SMART SM00228 421 506 7.9E-7 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_06545 15f71b3cea4672a76f14def51336217e 518 PRINTS PR00834 HtrA/DegQ protease family signature 229 246 1.2E-56 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_06545 15f71b3cea4672a76f14def51336217e 518 PRINTS PR00834 HtrA/DegQ protease family signature 251 268 1.2E-56 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_06545 15f71b3cea4672a76f14def51336217e 518 PRINTS PR00834 HtrA/DegQ protease family signature 195 219 1.2E-56 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_06545 15f71b3cea4672a76f14def51336217e 518 PRINTS PR00834 HtrA/DegQ protease family signature 154 174 1.2E-56 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_06545 15f71b3cea4672a76f14def51336217e 518 PRINTS PR00834 HtrA/DegQ protease family signature 133 145 1.2E-56 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_06545 15f71b3cea4672a76f14def51336217e 518 PRINTS PR00834 HtrA/DegQ protease family signature 337 349 1.2E-56 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_06545 15f71b3cea4672a76f14def51336217e 518 Pfam PF13365 Trypsin-like peptidase domain 123 258 1.2E-31 T 14-10-2018 TSH58p_06545 15f71b3cea4672a76f14def51336217e 518 SUPERFAMILY SSF50156 255 380 2.23E-25 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 TSH58p_06545 15f71b3cea4672a76f14def51336217e 518 Gene3D G3DSA:2.30.42.60 411 517 3.5E-17 T 14-10-2018 TSH58p_06545 15f71b3cea4672a76f14def51336217e 518 Gene3D G3DSA:2.40.10.120 55 291 3.6E-89 T 14-10-2018 TSH58p_06545 15f71b3cea4672a76f14def51336217e 518 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 56 512 2.1E-162 T 14-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 TSH58p_06545 15f71b3cea4672a76f14def51336217e 518 SUPERFAMILY SSF50156 422 514 1.97E-15 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 TSH58p_06545 15f71b3cea4672a76f14def51336217e 518 Pfam PF13180 PDZ domain 297 388 1.2E-18 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_06545 15f71b3cea4672a76f14def51336217e 518 Pfam PF13180 PDZ domain 423 512 3.6E-7 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_13745 5c3fb59b2e991a37b1e025876d972b19 413 SUPERFAMILY SSF82051 2 158 3.27E-55 T 14-10-2018 IPR036726 GTP1/OBG domain superfamily TSH58p_13745 5c3fb59b2e991a37b1e025876d972b19 413 Pfam PF01018 GTP1/OBG 5 158 3.2E-58 T 14-10-2018 IPR006169 GTP1/OBG domain TSH58p_13745 5c3fb59b2e991a37b1e025876d972b19 413 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 1.2E-33 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 TSH58p_13745 5c3fb59b2e991a37b1e025876d972b19 413 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 1.2E-33 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 TSH58p_13745 5c3fb59b2e991a37b1e025876d972b19 413 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 1.2E-33 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 TSH58p_13745 5c3fb59b2e991a37b1e025876d972b19 413 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 1.2E-33 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 TSH58p_13745 5c3fb59b2e991a37b1e025876d972b19 413 Gene3D G3DSA:3.40.50.300 161 358 1.3E-45 T 14-10-2018 TSH58p_13745 5c3fb59b2e991a37b1e025876d972b19 413 Hamap MF_01454 GTPase Obg [obg]. 2 327 45.788 T 14-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 TSH58p_13745 5c3fb59b2e991a37b1e025876d972b19 413 PIRSF PIRSF002401 1 356 2.1E-127 T 14-10-2018 IPR035101 GTP-binding protein, Obg-type TSH58p_13745 5c3fb59b2e991a37b1e025876d972b19 413 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 326 1.1E-135 T 14-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 TSH58p_13745 5c3fb59b2e991a37b1e025876d972b19 413 Gene3D G3DSA:2.70.210.12 1 158 3.0E-57 T 14-10-2018 IPR036726 GTP1/OBG domain superfamily TSH58p_13745 5c3fb59b2e991a37b1e025876d972b19 413 Pfam PF01926 50S ribosome-binding GTPase 163 279 1.6E-22 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 TSH58p_13745 5c3fb59b2e991a37b1e025876d972b19 413 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 14-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 TSH58p_13745 5c3fb59b2e991a37b1e025876d972b19 413 SUPERFAMILY SSF52540 150 334 1.1E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_07925 929a1e701acdb2d3440f452195b98529 216 Pfam PF00430 ATP synthase B/B' CF(0) 65 193 3.4E-18 T 14-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 TSH58p_07925 929a1e701acdb2d3440f452195b98529 216 Hamap MF_01398 ATP synthase subunit b [atpF]. 59 196 11.153 T 14-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 TSH58p_23435 2a1d3e5a96ffcefc1c02ded7ce713096 365 SUPERFAMILY SSF111369 44 277 1.83E-27 T 14-10-2018 TSH58p_23435 2a1d3e5a96ffcefc1c02ded7ce713096 365 Gene3D G3DSA:2.40.420.20 286 359 3.5E-59 T 14-10-2018 TSH58p_23435 2a1d3e5a96ffcefc1c02ded7ce713096 365 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 31 361 1.2E-68 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 TSH58p_23435 2a1d3e5a96ffcefc1c02ded7ce713096 365 Gene3D G3DSA:1.10.287.470 90 163 3.5E-59 T 14-10-2018 TSH58p_23435 2a1d3e5a96ffcefc1c02ded7ce713096 365 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 43 271 1.3E-27 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain TSH58p_23435 2a1d3e5a96ffcefc1c02ded7ce713096 365 Gene3D G3DSA:2.40.30.170 42 285 3.5E-59 T 14-10-2018 TSH58p_23435 2a1d3e5a96ffcefc1c02ded7ce713096 365 Gene3D G3DSA:2.40.50.100 55 197 3.5E-59 T 14-10-2018 TSH58p_11735 db9a343ae1f5e6e4d35c53d1343b21b8 164 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 8 153 35.155 T 14-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 TSH58p_11735 db9a343ae1f5e6e4d35c53d1343b21b8 164 Gene3D G3DSA:2.70.40.10 8 153 2.1E-54 T 14-10-2018 IPR036157 dUTPase-like superfamily TSH58p_11735 db9a343ae1f5e6e4d35c53d1343b21b8 164 SUPERFAMILY SSF51283 10 152 9.81E-53 T 14-10-2018 IPR036157 dUTPase-like superfamily TSH58p_11735 db9a343ae1f5e6e4d35c53d1343b21b8 164 Pfam PF00692 dUTPase 22 152 1.4E-31 T 14-10-2018 IPR029054 dUTPase-like TSH58p_11735 db9a343ae1f5e6e4d35c53d1343b21b8 164 TIGRFAM TIGR00576 dut: dUTP diphosphatase 17 153 6.0E-55 T 14-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 TSH58p_27515 2d1e7bf3a2cf25b2de72eeeecb7bfcdb 394 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 26 391 34.461 T 14-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 TSH58p_27515 2d1e7bf3a2cf25b2de72eeeecb7bfcdb 394 PIRSF PIRSF000876 23 394 3.1E-127 T 14-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 TSH58p_27515 2d1e7bf3a2cf25b2de72eeeecb7bfcdb 394 SUPERFAMILY SSF52738 203 391 6.54E-63 T 14-10-2018 IPR035909 Methylesterase CheB, C-terminal TSH58p_27515 2d1e7bf3a2cf25b2de72eeeecb7bfcdb 394 Pfam PF01339 CheB methylesterase 206 386 1.4E-54 T 14-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 TSH58p_27515 2d1e7bf3a2cf25b2de72eeeecb7bfcdb 394 Gene3D G3DSA:3.40.50.2300 24 166 2.0E-28 T 14-10-2018 TSH58p_27515 2d1e7bf3a2cf25b2de72eeeecb7bfcdb 394 Gene3D G3DSA:3.40.50.180 197 393 1.2E-64 T 14-10-2018 IPR035909 Methylesterase CheB, C-terminal TSH58p_27515 2d1e7bf3a2cf25b2de72eeeecb7bfcdb 394 SUPERFAMILY SSF52172 25 137 9.25E-27 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_27515 2d1e7bf3a2cf25b2de72eeeecb7bfcdb 394 SMART SM00448 26 141 3.5E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_27515 2d1e7bf3a2cf25b2de72eeeecb7bfcdb 394 Pfam PF00072 Response regulator receiver domain 28 137 2.0E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_04210 2135c3495aa70334716664e4c79726b5 165 SUPERFAMILY SSF47741 87 159 5.63E-34 T 14-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily TSH58p_04210 2135c3495aa70334716664e4c79726b5 165 Gene3D G3DSA:3.10.20.30 2 76 2.3E-29 T 14-10-2018 IPR012675 Beta-grasp domain superfamily TSH58p_04210 2135c3495aa70334716664e4c79726b5 165 Pfam PF01799 [2Fe-2S] binding domain 75 148 2.5E-31 T 14-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 TSH58p_04210 2135c3495aa70334716664e4c79726b5 165 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 61 1.3E-6 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 TSH58p_04210 2135c3495aa70334716664e4c79726b5 165 SUPERFAMILY SSF54292 4 80 1.97E-24 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TSH58p_04210 2135c3495aa70334716664e4c79726b5 165 Gene3D G3DSA:1.10.150.120 77 165 1.8E-34 T 14-10-2018 TSH58p_10905 7c836d7e6835b1cb34bd1d938c615f77 273 SUPERFAMILY SSF55166 67 184 4.71E-28 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSH58p_10905 7c836d7e6835b1cb34bd1d938c615f77 273 Gene3D G3DSA:3.30.1380.10 74 187 9.0E-14 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSH58p_10905 7c836d7e6835b1cb34bd1d938c615f77 273 Pfam PF05951 Bacterial protein of unknown function (DUF882) 34 182 4.9E-37 T 14-10-2018 IPR010275 Protein of unknown function DUF882 TSH58p_15025 22ee8e1202f415d1f4aeeb9bd543a054 434 SUPERFAMILY SSF56925 304 432 4.97E-5 T 14-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel TSH58p_15025 22ee8e1202f415d1f4aeeb9bd543a054 434 Pfam PF10082 Putative beta-barrel porin 2 43 434 6.7E-137 T 14-10-2018 IPR018759 Putative beta-barrel porin 2 TSH58p_02555 cabdf54cdf1f10f39f1e0f9a7f25aeb2 297 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 22 292 1.2E-49 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 TSH58p_02555 cabdf54cdf1f10f39f1e0f9a7f25aeb2 297 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 8 297 18.442 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 TSH58p_02555 cabdf54cdf1f10f39f1e0f9a7f25aeb2 297 Pfam PF01256 Carbohydrate kinase 32 288 7.8E-44 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 TSH58p_02555 cabdf54cdf1f10f39f1e0f9a7f25aeb2 297 SUPERFAMILY SSF53613 15 295 5.46E-56 T 14-10-2018 IPR029056 Ribokinase-like TSH58p_02555 cabdf54cdf1f10f39f1e0f9a7f25aeb2 297 Gene3D G3DSA:3.40.1190.20 7 295 4.6E-70 T 14-10-2018 IPR029056 Ribokinase-like TSH58p_08160 ab81c42eec88f9dc7ce37cb97bdc65bb 167 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 11 166 16.332 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TSH58p_08160 ab81c42eec88f9dc7ce37cb97bdc65bb 167 Pfam PF01252 Signal peptidase (SPase) II 20 161 5.5E-36 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TSH58p_08160 ab81c42eec88f9dc7ce37cb97bdc65bb 167 TIGRFAM TIGR00077 lspA: signal peptidase II 11 165 5.0E-34 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TSH58p_08160 ab81c42eec88f9dc7ce37cb97bdc65bb 167 ProSitePatterns PS00855 Signal peptidases II signature. 108 120 - T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TSH58p_08160 ab81c42eec88f9dc7ce37cb97bdc65bb 167 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 59 67 3.4E-16 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TSH58p_08160 ab81c42eec88f9dc7ce37cb97bdc65bb 167 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 141 157 3.4E-16 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TSH58p_08160 ab81c42eec88f9dc7ce37cb97bdc65bb 167 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 105 120 3.4E-16 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TSH58p_12435 397ccbf3b82eccf6f5b57386cb3f2311 303 SUPERFAMILY SSF103481 199 302 1.14E-14 T 14-10-2018 TSH58p_12435 397ccbf3b82eccf6f5b57386cb3f2311 303 SUPERFAMILY SSF103481 49 152 2.22E-15 T 14-10-2018 TSH58p_12435 397ccbf3b82eccf6f5b57386cb3f2311 303 Pfam PF00892 EamA-like transporter family 16 148 7.4E-25 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_12435 397ccbf3b82eccf6f5b57386cb3f2311 303 Pfam PF00892 EamA-like transporter family 164 298 9.6E-24 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_06235 499e4b3cbe935d082fb87f2111379169 480 Gene3D G3DSA:3.40.1380.20 340 473 2.2E-167 T 14-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_06235 499e4b3cbe935d082fb87f2111379169 480 SUPERFAMILY SSF52935 327 477 7.06E-38 T 14-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_06235 499e4b3cbe935d082fb87f2111379169 480 SUPERFAMILY SSF51621 9 346 2.13E-96 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSH58p_06235 499e4b3cbe935d082fb87f2111379169 480 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 13 475 8.4E-152 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_06235 499e4b3cbe935d082fb87f2111379169 480 Pfam PF00224 Pyruvate kinase, barrel domain 12 341 1.9E-111 T 14-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_06235 499e4b3cbe935d082fb87f2111379169 480 PRINTS PR01050 Pyruvate kinase family signature 248 272 2.9E-65 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_06235 499e4b3cbe935d082fb87f2111379169 480 PRINTS PR01050 Pyruvate kinase family signature 221 247 2.9E-65 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_06235 499e4b3cbe935d082fb87f2111379169 480 PRINTS PR01050 Pyruvate kinase family signature 298 316 2.9E-65 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_06235 499e4b3cbe935d082fb87f2111379169 480 PRINTS PR01050 Pyruvate kinase family signature 273 297 2.9E-65 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_06235 499e4b3cbe935d082fb87f2111379169 480 PRINTS PR01050 Pyruvate kinase family signature 317 333 2.9E-65 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_06235 499e4b3cbe935d082fb87f2111379169 480 PRINTS PR01050 Pyruvate kinase family signature 69 85 2.9E-65 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_06235 499e4b3cbe935d082fb87f2111379169 480 PRINTS PR01050 Pyruvate kinase family signature 194 208 2.9E-65 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_06235 499e4b3cbe935d082fb87f2111379169 480 Gene3D G3DSA:2.40.33.10 80 176 2.2E-167 T 14-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_06235 499e4b3cbe935d082fb87f2111379169 480 Pfam PF02887 Pyruvate kinase, alpha/beta domain 362 474 7.0E-31 T 14-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_06235 499e4b3cbe935d082fb87f2111379169 480 SUPERFAMILY SSF50800 80 175 1.13E-22 T 14-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily TSH58p_06235 499e4b3cbe935d082fb87f2111379169 480 Gene3D G3DSA:3.20.20.60 12 339 2.2E-167 T 14-10-2018 TSH58p_26625 a95f225fe90f877186603492f694bb77 1027 Pfam PF00924 Mechanosensitive ion channel 801 943 1.9E-26 T 14-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 TSH58p_26625 a95f225fe90f877186603492f694bb77 1027 Gene3D G3DSA:3.40.50.2300 59 400 1.7E-54 T 14-10-2018 TSH58p_26625 a95f225fe90f877186603492f694bb77 1027 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 96 114 1.2E-6 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_26625 a95f225fe90f877186603492f694bb77 1027 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 77 93 1.2E-6 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_26625 a95f225fe90f877186603492f694bb77 1027 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 55 71 1.2E-6 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_26625 a95f225fe90f877186603492f694bb77 1027 Pfam PF13458 Periplasmic binding protein 54 411 2.8E-40 T 14-10-2018 IPR028081 Leucine-binding protein domain TSH58p_26625 a95f225fe90f877186603492f694bb77 1027 SUPERFAMILY SSF53822 53 413 2.33E-47 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_26625 a95f225fe90f877186603492f694bb77 1027 Gene3D G3DSA:3.40.50.2300 172 324 1.7E-54 T 14-10-2018 TSH58p_26625 a95f225fe90f877186603492f694bb77 1027 SUPERFAMILY SSF50182 841 906 2.26E-12 T 14-10-2018 IPR010920 LSM domain superfamily TSH58p_26625 a95f225fe90f877186603492f694bb77 1027 Gene3D G3DSA:2.30.30.60 855 906 9.5E-8 T 14-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily TSH58p_08675 cd474e18ef50a1aeed9e5e94219e1e2d 277 Pfam PF00557 Metallopeptidase family M24 20 248 3.8E-53 T 14-10-2018 IPR000994 Peptidase M24 TSH58p_08675 cd474e18ef50a1aeed9e5e94219e1e2d 277 Gene3D G3DSA:3.90.230.10 7 266 3.7E-108 T 14-10-2018 TSH58p_08675 cd474e18ef50a1aeed9e5e94219e1e2d 277 PRINTS PR00599 Methionine aminopeptidase-1 signature 98 114 1.0E-21 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSH58p_08675 cd474e18ef50a1aeed9e5e94219e1e2d 277 PRINTS PR00599 Methionine aminopeptidase-1 signature 199 211 1.0E-21 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSH58p_08675 cd474e18ef50a1aeed9e5e94219e1e2d 277 PRINTS PR00599 Methionine aminopeptidase-1 signature 76 89 1.0E-21 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSH58p_08675 cd474e18ef50a1aeed9e5e94219e1e2d 277 PRINTS PR00599 Methionine aminopeptidase-1 signature 168 180 1.0E-21 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSH58p_08675 cd474e18ef50a1aeed9e5e94219e1e2d 277 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 11 256 3.4E-93 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSH58p_08675 cd474e18ef50a1aeed9e5e94219e1e2d 277 Hamap MF_01974 Methionine aminopeptidase [map]. 11 257 41.616 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSH58p_08675 cd474e18ef50a1aeed9e5e94219e1e2d 277 SUPERFAMILY SSF55920 12 260 1.83E-90 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like TSH58p_08675 cd474e18ef50a1aeed9e5e94219e1e2d 277 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 174 192 - T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSH58p_07990 424627711f9a887ce79f58a742a168f7 194 Pfam PF11748 Protein of unknown function (DUF3306) 5 114 2.2E-29 T 14-10-2018 IPR021735 Protein of unknown function DUF3306 TSH58p_01935 fc568e1dcaa188d19fed3741fded6763 477 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 323 453 4.0E-8 T 14-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain TSH58p_01935 fc568e1dcaa188d19fed3741fded6763 477 Pfam PF13440 Polysaccharide biosynthesis protein 25 317 6.7E-19 T 14-10-2018 TSH58p_32630 8381819ce7abaec3bcffafbeae65c03f 744 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 92 742 3.0E-104 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 TSH58p_32630 8381819ce7abaec3bcffafbeae65c03f 744 Gene3D G3DSA:2.40.170.20 202 744 2.6E-135 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily TSH58p_32630 8381819ce7abaec3bcffafbeae65c03f 744 Gene3D G3DSA:2.170.130.10 67 201 1.9E-34 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily TSH58p_32630 8381819ce7abaec3bcffafbeae65c03f 744 Pfam PF07715 TonB-dependent Receptor Plug Domain 91 193 5.2E-20 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain TSH58p_32630 8381819ce7abaec3bcffafbeae65c03f 744 Pfam PF00593 TonB dependent receptor 298 743 2.0E-58 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel TSH58p_32630 8381819ce7abaec3bcffafbeae65c03f 744 SUPERFAMILY SSF56935 82 744 1.22E-131 T 14-10-2018 TSH58p_08070 976e29b59528a79abf8a24731ae855fd 158 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 55 92 - T 14-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 TSH58p_08070 976e29b59528a79abf8a24731ae855fd 158 Gene3D G3DSA:3.40.140.10 5 158 3.3E-58 T 14-10-2018 TSH58p_08070 976e29b59528a79abf8a24731ae855fd 158 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 6 103 5.8E-24 T 14-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain TSH58p_08070 976e29b59528a79abf8a24731ae855fd 158 SUPERFAMILY SSF53927 2 155 1.47E-47 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TSH58p_03075 816338f07883e9c57d81fb9f6ab0e8e5 399 Gene3D G3DSA:3.40.630.30 158 325 3.5E-41 T 14-10-2018 TSH58p_03075 816338f07883e9c57d81fb9f6ab0e8e5 399 SUPERFAMILY SSF55729 22 157 2.6E-12 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_03075 816338f07883e9c57d81fb9f6ab0e8e5 399 SUPERFAMILY SSF55729 173 325 1.59E-27 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_03075 816338f07883e9c57d81fb9f6ab0e8e5 399 Gene3D G3DSA:3.40.630.30 35 332 3.5E-41 T 14-10-2018 TSH58p_03075 816338f07883e9c57d81fb9f6ab0e8e5 399 Pfam PF13480 Acetyltransferase (GNAT) domain 174 314 3.4E-12 T 14-10-2018 IPR038740 BioF2-like, acetyltransferase domain KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 TSH58p_26805 e1b4600d960b75532ef30beb3725e5cd 686 Hamap MF_02090 Glutamine-dependent NAD(+) synthetase [nadE]. 12 674 28.264 T 14-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 TSH58p_26805 e1b4600d960b75532ef30beb3725e5cd 686 Gene3D G3DSA:3.40.50.620 330 549 5.9E-64 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_26805 e1b4600d960b75532ef30beb3725e5cd 686 Gene3D G3DSA:1.10.10.1140 564 686 4.3E-51 T 14-10-2018 TSH58p_26805 e1b4600d960b75532ef30beb3725e5cd 686 Pfam PF00795 Carbon-nitrogen hydrolase 13 290 1.5E-12 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 TSH58p_26805 e1b4600d960b75532ef30beb3725e5cd 686 SUPERFAMILY SSF52402 331 653 4.68E-64 T 14-10-2018 TSH58p_26805 e1b4600d960b75532ef30beb3725e5cd 686 SUPERFAMILY SSF56317 11 304 1.44E-48 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TSH58p_26805 e1b4600d960b75532ef30beb3725e5cd 686 PIRSF PIRSF006630 9 676 3.8E-164 T 14-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 TSH58p_26805 e1b4600d960b75532ef30beb3725e5cd 686 Gene3D G3DSA:3.60.110.10 1 328 4.2E-85 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TSH58p_26805 e1b4600d960b75532ef30beb3725e5cd 686 Pfam PF02540 NAD synthase 353 527 5.7E-22 T 14-10-2018 IPR022310 NAD/GMP synthase TSH58p_24400 dda3153c8291bccec3e007dd1e8153df 895 Gene3D G3DSA:1.20.1640.10 457 469 1.5E-7 T 14-10-2018 TSH58p_24400 dda3153c8291bccec3e007dd1e8153df 895 Gene3D G3DSA:3.30.70.1440 87 285 8.4E-6 T 14-10-2018 TSH58p_24400 dda3153c8291bccec3e007dd1e8153df 895 Gene3D G3DSA:1.20.1640.10 695 894 3.8E-9 T 14-10-2018 TSH58p_24400 dda3153c8291bccec3e007dd1e8153df 895 Pfam PF03176 MMPL family 638 889 6.0E-15 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 TSH58p_24400 dda3153c8291bccec3e007dd1e8153df 895 Pfam PF03176 MMPL family 251 459 8.5E-20 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 TSH58p_24400 dda3153c8291bccec3e007dd1e8153df 895 TIGRFAM TIGR03480 HpnN: hopanoid biosynthesis associated RND transporter like protein HpnN 21 878 7.1E-242 T 14-10-2018 IPR017841 Hopanoid biosynthesis associated RND transporter-like protein HpnN TSH58p_24400 dda3153c8291bccec3e007dd1e8153df 895 SUPERFAMILY SSF82866 243 442 1.96E-26 T 14-10-2018 TSH58p_24400 dda3153c8291bccec3e007dd1e8153df 895 SUPERFAMILY SSF82866 688 886 1.57E-29 T 14-10-2018 TSH58p_24400 dda3153c8291bccec3e007dd1e8153df 895 Gene3D G3DSA:1.20.1640.10 368 456 1.5E-7 T 14-10-2018 TSH58p_24400 dda3153c8291bccec3e007dd1e8153df 895 Gene3D G3DSA:1.20.1640.10 286 352 8.4E-6 T 14-10-2018 TSH58p_24400 dda3153c8291bccec3e007dd1e8153df 895 Gene3D G3DSA:3.30.2090.10 131 223 8.4E-6 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_01510 3c7bab18df0434bae91cd4a0518ae3db 221 SUPERFAMILY SSF161098 14 203 2.88E-43 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_01510 3c7bab18df0434bae91cd4a0518ae3db 221 Gene3D G3DSA:1.10.3720.10 4 219 3.0E-52 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_01510 3c7bab18df0434bae91cd4a0518ae3db 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 218 5.1E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_01510 3c7bab18df0434bae91cd4a0518ae3db 221 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 112 4.1E-27 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 TSH58p_08305 4ebfa088b2f9f5c38483c25cba8386eb 114 Pfam PF01042 Endoribonuclease L-PSP 8 113 9.0E-26 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 TSH58p_08305 4ebfa088b2f9f5c38483c25cba8386eb 114 Gene3D G3DSA:3.30.1330.40 1 114 2.1E-40 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TSH58p_08305 4ebfa088b2f9f5c38483c25cba8386eb 114 SUPERFAMILY SSF55298 5 113 1.38E-30 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TSH58p_19930 6f500ba999a2384c9a549896f70d403c 794 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 371 532 2.0E-37 T 14-10-2018 IPR000160 GGDEF domain TSH58p_19930 6f500ba999a2384c9a549896f70d403c 794 Gene3D G3DSA:3.30.70.270 368 546 1.3E-58 T 14-10-2018 TSH58p_19930 6f500ba999a2384c9a549896f70d403c 794 SUPERFAMILY SSF141868 549 792 5.75E-91 T 14-10-2018 IPR035919 EAL domain superfamily TSH58p_19930 6f500ba999a2384c9a549896f70d403c 794 Pfam PF13426 PAS domain 267 362 3.6E-9 T 14-10-2018 IPR000014 PAS domain TSH58p_19930 6f500ba999a2384c9a549896f70d403c 794 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 252 369 5.0E-17 T 14-10-2018 IPR000014 PAS domain TSH58p_19930 6f500ba999a2384c9a549896f70d403c 794 SUPERFAMILY SSF55785 249 360 4.54E-16 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_19930 6f500ba999a2384c9a549896f70d403c 794 SMART SM00267 363 534 7.3E-60 T 14-10-2018 IPR000160 GGDEF domain TSH58p_19930 6f500ba999a2384c9a549896f70d403c 794 Pfam PF03707 Bacterial signalling protein N terminal repeat 58 108 1.9E-11 T 14-10-2018 IPR005330 MHYT domain TSH58p_19930 6f500ba999a2384c9a549896f70d403c 794 Pfam PF03707 Bacterial signalling protein N terminal repeat 182 244 1.6E-6 T 14-10-2018 IPR005330 MHYT domain TSH58p_19930 6f500ba999a2384c9a549896f70d403c 794 Pfam PF03707 Bacterial signalling protein N terminal repeat 119 171 1.9E-10 T 14-10-2018 IPR005330 MHYT domain TSH58p_19930 6f500ba999a2384c9a549896f70d403c 794 SMART SM00091 256 321 1.3E-6 T 14-10-2018 IPR000014 PAS domain TSH58p_19930 6f500ba999a2384c9a549896f70d403c 794 Gene3D G3DSA:3.20.20.450 547 794 9.5E-99 T 14-10-2018 IPR035919 EAL domain superfamily TSH58p_19930 6f500ba999a2384c9a549896f70d403c 794 SMART SM00052 544 786 7.0E-117 T 14-10-2018 IPR001633 EAL domain TSH58p_19930 6f500ba999a2384c9a549896f70d403c 794 SUPERFAMILY SSF55073 379 535 8.63E-49 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_19930 6f500ba999a2384c9a549896f70d403c 794 Gene3D G3DSA:3.30.450.20 242 360 1.6E-18 T 14-10-2018 TSH58p_19930 6f500ba999a2384c9a549896f70d403c 794 Pfam PF00990 Diguanylate cyclase, GGDEF domain 374 529 9.0E-44 T 14-10-2018 IPR000160 GGDEF domain TSH58p_19930 6f500ba999a2384c9a549896f70d403c 794 Pfam PF00563 EAL domain 550 781 2.0E-73 T 14-10-2018 IPR001633 EAL domain TSH58p_26330 07202c490650c76a860871ba271acef9 330 Gene3D G3DSA:3.40.630.30 139 327 5.0E-21 T 14-10-2018 TSH58p_26330 07202c490650c76a860871ba271acef9 330 SUPERFAMILY SSF55729 18 117 1.16E-8 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_26330 07202c490650c76a860871ba271acef9 330 SUPERFAMILY SSF55729 158 329 4.5E-21 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_26330 07202c490650c76a860871ba271acef9 330 Pfam PF13480 Acetyltransferase (GNAT) domain 168 304 4.4E-9 T 14-10-2018 IPR038740 BioF2-like, acetyltransferase domain KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 TSH58p_08975 5bafe360949416398adbdd6082ad60e9 157 Pfam PF03449 Transcription elongation factor, N-terminal 4 74 3.1E-34 T 14-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 TSH58p_08975 5bafe360949416398adbdd6082ad60e9 157 SUPERFAMILY SSF46557 3 78 3.53E-30 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 TSH58p_08975 5bafe360949416398adbdd6082ad60e9 157 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 14-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 TSH58p_08975 5bafe360949416398adbdd6082ad60e9 157 PIRSF PIRSF006092 1 157 3.7E-56 T 14-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 TSH58p_08975 5bafe360949416398adbdd6082ad60e9 157 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 155 33.459 T 14-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 TSH58p_08975 5bafe360949416398adbdd6082ad60e9 157 Gene3D G3DSA:1.10.287.180 1 75 6.5E-34 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 TSH58p_08975 5bafe360949416398adbdd6082ad60e9 157 SUPERFAMILY SSF54534 81 155 1.19E-23 T 14-10-2018 TSH58p_08975 5bafe360949416398adbdd6082ad60e9 157 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 154 1.7E-62 T 14-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 TSH58p_08975 5bafe360949416398adbdd6082ad60e9 157 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 82 155 1.3E-28 T 14-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 TSH58p_08975 5bafe360949416398adbdd6082ad60e9 157 Gene3D G3DSA:3.10.50.30 77 156 1.1E-28 T 14-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 TSH58p_19890 bfc7a3563d5f9df10d743205eaf21ee7 312 Gene3D G3DSA:3.10.20.30 216 312 4.4E-25 T 14-10-2018 IPR012675 Beta-grasp domain superfamily TSH58p_19890 bfc7a3563d5f9df10d743205eaf21ee7 312 Gene3D G3DSA:2.40.30.10 1 93 5.7E-28 T 14-10-2018 TSH58p_19890 bfc7a3563d5f9df10d743205eaf21ee7 312 Pfam PF00970 Oxidoreductase FAD-binding domain 2 95 6.6E-6 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 TSH58p_19890 bfc7a3563d5f9df10d743205eaf21ee7 312 Pfam PF00175 Oxidoreductase NAD-binding domain 104 197 1.5E-7 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 TSH58p_19890 bfc7a3563d5f9df10d743205eaf21ee7 312 Gene3D G3DSA:3.40.50.80 97 211 5.2E-25 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TSH58p_19890 bfc7a3563d5f9df10d743205eaf21ee7 312 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 261 269 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 TSH58p_19890 bfc7a3563d5f9df10d743205eaf21ee7 312 SUPERFAMILY SSF63380 1 92 3.94E-25 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TSH58p_19890 bfc7a3563d5f9df10d743205eaf21ee7 312 SUPERFAMILY SSF54292 203 312 4.59E-26 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TSH58p_19890 bfc7a3563d5f9df10d743205eaf21ee7 312 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 234 303 1.4E-11 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 TSH58p_19890 bfc7a3563d5f9df10d743205eaf21ee7 312 SUPERFAMILY SSF52343 97 204 1.44E-25 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TSH58p_19890 bfc7a3563d5f9df10d743205eaf21ee7 312 PRINTS PR00409 Phthalate dioxygenase reductase family signature 23 33 2.2E-29 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 TSH58p_19890 bfc7a3563d5f9df10d743205eaf21ee7 312 PRINTS PR00409 Phthalate dioxygenase reductase family signature 103 122 2.2E-29 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 TSH58p_19890 bfc7a3563d5f9df10d743205eaf21ee7 312 PRINTS PR00409 Phthalate dioxygenase reductase family signature 128 137 2.2E-29 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 TSH58p_19890 bfc7a3563d5f9df10d743205eaf21ee7 312 PRINTS PR00409 Phthalate dioxygenase reductase family signature 33 45 2.2E-29 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 TSH58p_19890 bfc7a3563d5f9df10d743205eaf21ee7 312 PRINTS PR00409 Phthalate dioxygenase reductase family signature 45 59 2.2E-29 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 TSH58p_19890 bfc7a3563d5f9df10d743205eaf21ee7 312 PRINTS PR00409 Phthalate dioxygenase reductase family signature 183 191 2.2E-29 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 TSH58p_06000 df10e232333cc3a63f3600f40ed8582b 264 PIRSF PIRSF016184 1 264 8.6E-57 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 TSH58p_06000 df10e232333cc3a63f3600f40ed8582b 264 SUPERFAMILY SSF54506 2 264 3.44E-83 T 14-10-2018 TSH58p_06000 df10e232333cc3a63f3600f40ed8582b 264 Pfam PF02567 Phenazine biosynthesis-like protein 8 260 1.0E-55 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 TSH58p_06000 df10e232333cc3a63f3600f40ed8582b 264 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 2 262 9.4E-41 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 TSH58p_06000 df10e232333cc3a63f3600f40ed8582b 264 Gene3D G3DSA:3.10.310.10 118 252 3.3E-94 T 14-10-2018 TSH58p_06000 df10e232333cc3a63f3600f40ed8582b 264 Gene3D G3DSA:3.10.310.10 6 260 3.3E-94 T 14-10-2018 TSH58p_27010 882aab8ba8b6a94b07ed6d4ff45cceb1 545 Pfam PF00990 Diguanylate cyclase, GGDEF domain 385 538 6.4E-48 T 14-10-2018 IPR000160 GGDEF domain TSH58p_27010 882aab8ba8b6a94b07ed6d4ff45cceb1 545 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 382 537 4.0E-44 T 14-10-2018 IPR000160 GGDEF domain TSH58p_27010 882aab8ba8b6a94b07ed6d4ff45cceb1 545 SUPERFAMILY SSF55073 390 538 4.0E-50 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_27010 882aab8ba8b6a94b07ed6d4ff45cceb1 545 SUPERFAMILY SSF158472 319 369 4.05E-8 T 14-10-2018 TSH58p_27010 882aab8ba8b6a94b07ed6d4ff45cceb1 545 SMART SM00304 319 372 1.6E-6 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_27010 882aab8ba8b6a94b07ed6d4ff45cceb1 545 Pfam PF00672 HAMP domain 319 368 9.3E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_27010 882aab8ba8b6a94b07ed6d4ff45cceb1 545 Gene3D G3DSA:3.30.70.270 379 543 2.0E-59 T 14-10-2018 TSH58p_27010 882aab8ba8b6a94b07ed6d4ff45cceb1 545 Gene3D G3DSA:1.20.1480.50 284 377 8.3E-9 T 14-10-2018 TSH58p_27010 882aab8ba8b6a94b07ed6d4ff45cceb1 545 SMART SM00267 374 545 3.4E-61 T 14-10-2018 IPR000160 GGDEF domain TSH58p_27010 882aab8ba8b6a94b07ed6d4ff45cceb1 545 Pfam PF02743 Cache domain 51 281 1.7E-21 T 14-10-2018 IPR033479 Double Cache domain 1 TSH58p_27010 882aab8ba8b6a94b07ed6d4ff45cceb1 545 Gene3D G3DSA:3.30.450.20 45 189 2.7E-20 T 14-10-2018 TSH58p_12190 e1ad7b921eb8392ed63a8ba7edc11304 253 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 21 252 53.961 T 14-10-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 TSH58p_12190 e1ad7b921eb8392ed63a8ba7edc11304 253 Gene3D G3DSA:3.30.1600.10 37 174 8.2E-77 T 14-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily TSH58p_12190 e1ad7b921eb8392ed63a8ba7edc11304 253 Pfam PF02146 Sir2 family 28 202 1.7E-46 T 14-10-2018 IPR003000 Sirtuin family GO:0070403 TSH58p_12190 e1ad7b921eb8392ed63a8ba7edc11304 253 SUPERFAMILY SSF52467 6 250 2.48E-72 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TSH58p_12190 e1ad7b921eb8392ed63a8ba7edc11304 253 Gene3D G3DSA:3.40.50.1220 23 244 8.2E-77 T 14-10-2018 TSH58p_12840 838ea6acc29cc2ffe3248748d3b0a999 90 Gene3D G3DSA:3.30.300.90 2 90 4.7E-32 T 14-10-2018 TSH58p_12840 838ea6acc29cc2ffe3248748d3b0a999 90 PIRSF PIRSF003113 1 90 1.4E-30 T 14-10-2018 IPR002634 BolA protein TSH58p_12840 838ea6acc29cc2ffe3248748d3b0a999 90 SUPERFAMILY SSF82657 2 88 5.1E-27 T 14-10-2018 IPR036065 BolA-like superfamily TSH58p_12840 838ea6acc29cc2ffe3248748d3b0a999 90 Pfam PF01722 BolA-like protein 11 88 1.9E-30 T 14-10-2018 IPR002634 BolA protein TSH58p_21350 e76c5683f525ff17295437a406d1c9cb 321 SUPERFAMILY SSF53822 27 313 8.8E-77 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_21350 e76c5683f525ff17295437a406d1c9cb 321 Gene3D G3DSA:3.40.50.2300 133 273 2.6E-109 T 14-10-2018 TSH58p_21350 e76c5683f525ff17295437a406d1c9cb 321 Pfam PF13407 Periplasmic binding protein domain 33 279 6.3E-47 T 14-10-2018 IPR025997 Periplasmic binding protein TSH58p_21350 e76c5683f525ff17295437a406d1c9cb 321 Gene3D G3DSA:3.40.50.2300 32 291 2.6E-109 T 14-10-2018 TSH58p_27885 36464549a2de23342663e3bd1aefed41 1621 Gene3D G3DSA:2.60.40.1930 384 475 1.9E-10 T 14-10-2018 TSH58p_27885 36464549a2de23342663e3bd1aefed41 1621 Gene3D G3DSA:1.50.10.20 1162 1426 5.8E-17 T 14-10-2018 TSH58p_27885 36464549a2de23342663e3bd1aefed41 1621 SMART SM01359 749 896 1.9E-22 T 14-10-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 TSH58p_27885 36464549a2de23342663e3bd1aefed41 1621 Pfam PF00207 Alpha-2-macroglobulin family 960 1037 4.4E-8 T 14-10-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 TSH58p_27885 36464549a2de23342663e3bd1aefed41 1621 SMART SM01360 959 1048 3.6E-27 T 14-10-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 TSH58p_27885 36464549a2de23342663e3bd1aefed41 1621 SUPERFAMILY SSF48239 1159 1406 1.15E-25 T 14-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TSH58p_27885 36464549a2de23342663e3bd1aefed41 1621 PIRSF PIRSF038980 15 1621 0.0 T 14-10-2018 IPR026284 Alpha-2-macroglobulin domain protein, bacteria TSH58p_27885 36464549a2de23342663e3bd1aefed41 1621 Pfam PF07703 Alpha-2-macroglobulin family N-terminal region 757 896 2.2E-10 T 14-10-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 TSH58p_27885 36464549a2de23342663e3bd1aefed41 1621 Pfam PF01835 MG2 domain 384 469 1.7E-23 T 14-10-2018 IPR002890 Alpha-2-macroglobulin, N-terminal GO:0004866 TSH58p_27885 36464549a2de23342663e3bd1aefed41 1621 Pfam PF11974 Alpha-2-macroglobulin MG1 domain 263 348 1.4E-13 T 14-10-2018 TSH58p_11570 887b01db567e728f9cf584a31d7ea277 175 Gene3D G3DSA:2.60.40.2230 24 175 7.4E-32 T 14-10-2018 IPR038507 YcnI-like superfamily TSH58p_11570 887b01db567e728f9cf584a31d7ea277 175 Pfam PF07987 Domain of unkown function (DUF1775) 26 171 1.5E-49 T 14-10-2018 IPR012533 YcnI-like TSH58p_00800 c1d64d0638a27e027575f9a10946dafa 195 Gene3D G3DSA:1.20.1260.10 43 187 2.4E-11 T 14-10-2018 IPR012347 Ferritin-like TSH58p_00800 c1d64d0638a27e027575f9a10946dafa 195 Pfam PF13628 Domain of unknown function (DUF4142) 52 187 2.6E-40 T 14-10-2018 IPR025419 Domain of unknown function DUF4142 TSH58p_10505 6c5a259e5085b1f71775c5d6e7edd02a 280 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 58 206 1.4E-31 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TSH58p_10505 6c5a259e5085b1f71775c5d6e7edd02a 280 SUPERFAMILY SSF52518 22 215 1.81E-70 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_10505 6c5a259e5085b1f71775c5d6e7edd02a 280 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 24 214 6.6E-79 T 14-10-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate TSH58p_10505 6c5a259e5085b1f71775c5d6e7edd02a 280 Gene3D G3DSA:3.40.50.970 80 225 7.5E-27 T 14-10-2018 TSH58p_31460 3cc144d115adbeb1eca9c4a473ea1166 435 TIGRFAM TIGR02630 xylose_isom_A: xylose isomerase 5 434 6.1E-194 T 14-10-2018 IPR013452 Xylose isomerase, bacterial-type GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 TSH58p_31460 3cc144d115adbeb1eca9c4a473ea1166 435 SUPERFAMILY SSF51658 4 434 7.62E-160 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily TSH58p_31460 3cc144d115adbeb1eca9c4a473ea1166 435 Hamap MF_00455 Xylose isomerase [xylA]. 12 435 49.605 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 TSH58p_31460 3cc144d115adbeb1eca9c4a473ea1166 435 PRINTS PR00688 Xylose isomerase signature 134 154 3.6E-82 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 TSH58p_31460 3cc144d115adbeb1eca9c4a473ea1166 435 PRINTS PR00688 Xylose isomerase signature 181 202 3.6E-82 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 TSH58p_31460 3cc144d115adbeb1eca9c4a473ea1166 435 PRINTS PR00688 Xylose isomerase signature 208 227 3.6E-82 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 TSH58p_31460 3cc144d115adbeb1eca9c4a473ea1166 435 PRINTS PR00688 Xylose isomerase signature 272 299 3.6E-82 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 TSH58p_31460 3cc144d115adbeb1eca9c4a473ea1166 435 PRINTS PR00688 Xylose isomerase signature 93 115 3.6E-82 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 TSH58p_31460 3cc144d115adbeb1eca9c4a473ea1166 435 PRINTS PR00688 Xylose isomerase signature 230 254 3.6E-82 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 TSH58p_31460 3cc144d115adbeb1eca9c4a473ea1166 435 PRINTS PR00688 Xylose isomerase signature 301 312 3.6E-82 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 TSH58p_31460 3cc144d115adbeb1eca9c4a473ea1166 435 PRINTS PR00688 Xylose isomerase signature 157 176 3.6E-82 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 TSH58p_31460 3cc144d115adbeb1eca9c4a473ea1166 435 PRINTS PR00688 Xylose isomerase signature 334 345 3.6E-82 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 TSH58p_31460 3cc144d115adbeb1eca9c4a473ea1166 435 Gene3D G3DSA:3.20.20.150 3 435 1.0E-162 T 14-10-2018 TSH58p_28695 b87f8143a6eb1a5a8ce6879e4eeeb711 266 Gene3D G3DSA:3.40.190.10 126 217 3.2E-61 T 14-10-2018 TSH58p_28695 b87f8143a6eb1a5a8ce6879e4eeeb711 266 Gene3D G3DSA:3.40.190.10 34 250 3.2E-61 T 14-10-2018 TSH58p_28695 b87f8143a6eb1a5a8ce6879e4eeeb711 266 SMART SM00062 39 259 2.1E-54 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_28695 b87f8143a6eb1a5a8ce6879e4eeeb711 266 SUPERFAMILY SSF53850 14 259 9.2E-61 T 14-10-2018 TSH58p_28695 b87f8143a6eb1a5a8ce6879e4eeeb711 266 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 257 2.5E-56 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_27665 10e6214e01576d6f4b095eb231bf5a77 575 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 382 566 9.5E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_27665 10e6214e01576d6f4b095eb231bf5a77 575 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 289 9.2E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_27665 10e6214e01576d6f4b095eb231bf5a77 575 Gene3D G3DSA:1.10.3720.10 307 566 6.8E-38 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_27665 10e6214e01576d6f4b095eb231bf5a77 575 SUPERFAMILY SSF161098 303 565 1.24E-41 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_27665 10e6214e01576d6f4b095eb231bf5a77 575 SUPERFAMILY SSF161098 25 276 2.49E-41 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_27665 10e6214e01576d6f4b095eb231bf5a77 575 Gene3D G3DSA:1.10.3720.10 23 285 5.1E-48 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_02475 d09c7270c7f2e3490f8447d8c14aeb63 354 SUPERFAMILY SSF52151 20 341 8.63E-51 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TSH58p_02475 d09c7270c7f2e3490f8447d8c14aeb63 354 Pfam PF01734 Patatin-like phospholipase 24 220 8.6E-18 T 14-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 TSH58p_02475 d09c7270c7f2e3490f8447d8c14aeb63 354 Gene3D G3DSA:3.40.1090.10 8 132 9.9E-14 T 14-10-2018 TSH58p_02475 d09c7270c7f2e3490f8447d8c14aeb63 354 Gene3D G3DSA:3.40.1090.10 133 272 9.6E-13 T 14-10-2018 TSH58p_06030 69eb6b62469543668391de532e2a3593 464 SMART SM00345 19 78 1.2E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_06030 69eb6b62469543668391de532e2a3593 464 SUPERFAMILY SSF53383 94 454 2.63E-70 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_06030 69eb6b62469543668391de532e2a3593 464 SUPERFAMILY SSF46785 12 82 1.17E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_06030 69eb6b62469543668391de532e2a3593 464 Gene3D G3DSA:3.40.640.10 135 350 8.0E-64 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_06030 69eb6b62469543668391de532e2a3593 464 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 78 6.9E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_06030 69eb6b62469543668391de532e2a3593 464 Gene3D G3DSA:3.90.1150.10 124 451 8.0E-64 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_06030 69eb6b62469543668391de532e2a3593 464 Gene3D G3DSA:1.10.10.10 9 79 3.3E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_06030 69eb6b62469543668391de532e2a3593 464 Pfam PF00155 Aminotransferase class I and II 131 435 1.4E-20 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSH58p_20260 3534e9687662af58a3650bfe7ff3d3b4 111 SUPERFAMILY SSF54909 7 106 7.38E-26 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel TSH58p_20260 3534e9687662af58a3650bfe7ff3d3b4 111 Gene3D G3DSA:3.30.70.100 7 107 1.6E-23 T 14-10-2018 TSH58p_20260 3534e9687662af58a3650bfe7ff3d3b4 111 Pfam PF03992 Antibiotic biosynthesis monooxygenase 15 86 8.3E-15 T 14-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain TSH58p_00760 8b2d7e8cd6bf637f16133f6c10991ac7 549 ProSitePatterns PS00211 ABC transporters family signature. 461 475 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_00760 8b2d7e8cd6bf637f16133f6c10991ac7 549 SMART SM00382 361 537 8.8E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_00760 8b2d7e8cd6bf637f16133f6c10991ac7 549 Gene3D G3DSA:1.20.1560.10 13 308 5.4E-8 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_00760 8b2d7e8cd6bf637f16133f6c10991ac7 549 SUPERFAMILY SSF90123 16 307 4.84E-15 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_00760 8b2d7e8cd6bf637f16133f6c10991ac7 549 Pfam PF00005 ABC transporter 355 488 1.3E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_00760 8b2d7e8cd6bf637f16133f6c10991ac7 549 SUPERFAMILY SSF52540 332 540 2.42E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_00760 8b2d7e8cd6bf637f16133f6c10991ac7 549 Gene3D G3DSA:3.40.50.300 330 545 9.2E-38 T 14-10-2018 TSH58p_16365 1c5e2f00420dfa55398c670efe5896e5 658 SUPERFAMILY SSF52402 243 637 1.4E-92 T 14-10-2018 TSH58p_16365 1c5e2f00420dfa55398c670efe5896e5 658 Pfam PF13537 Glutamine amidotransferase domain 53 174 7.2E-46 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain TSH58p_16365 1c5e2f00420dfa55398c670efe5896e5 658 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 22 577 1.0E-148 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 TSH58p_16365 1c5e2f00420dfa55398c670efe5896e5 658 PIRSF PIRSF001589 2 657 1.6E-170 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 TSH58p_16365 1c5e2f00420dfa55398c670efe5896e5 658 Pfam PF00733 Asparagine synthase 254 641 9.6E-119 T 14-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 TSH58p_16365 1c5e2f00420dfa55398c670efe5896e5 658 SUPERFAMILY SSF56235 27 230 1.37E-63 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_16365 1c5e2f00420dfa55398c670efe5896e5 658 Gene3D G3DSA:3.60.20.10 14 192 1.6E-61 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_09155 77fdb0a5c7514bba417a26e0d531fb8e 291 Pfam PF13344 Haloacid dehalogenase-like hydrolase 20 124 2.3E-18 T 14-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA TSH58p_09155 77fdb0a5c7514bba417a26e0d531fb8e 291 Gene3D G3DSA:3.40.50.1000 18 256 3.2E-56 T 14-10-2018 IPR023214 HAD superfamily TSH58p_09155 77fdb0a5c7514bba417a26e0d531fb8e 291 SUPERFAMILY SSF56784 16 263 1.65E-49 T 14-10-2018 IPR036412 HAD-like superfamily TSH58p_09155 77fdb0a5c7514bba417a26e0d531fb8e 291 Gene3D G3DSA:3.40.50.1000 85 202 3.2E-56 T 14-10-2018 IPR023214 HAD superfamily TSH58p_09155 77fdb0a5c7514bba417a26e0d531fb8e 291 TIGRFAM TIGR01459 HAD-SF-IIA-hyp4: HAD hydrolase, TIGR01459 family 10 249 1.2E-57 T 14-10-2018 IPR006356 HAD-superfamily hydrolase, subfamily IIA, hypothetical 3 TSH58p_09155 77fdb0a5c7514bba417a26e0d531fb8e 291 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 20 250 9.6E-38 T 14-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA TSH58p_09155 77fdb0a5c7514bba417a26e0d531fb8e 291 Pfam PF13242 HAD-hyrolase-like 203 261 2.8E-14 T 14-10-2018 TSH58p_16165 1557b27a67acd15a53a002d51bba25ae 525 SUPERFAMILY SSF53383 71 514 2.51E-101 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_16165 1557b27a67acd15a53a002d51bba25ae 525 Gene3D G3DSA:3.90.1150.10 373 500 1.3E-39 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_16165 1557b27a67acd15a53a002d51bba25ae 525 Gene3D G3DSA:3.40.640.10 112 372 1.8E-55 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_16165 1557b27a67acd15a53a002d51bba25ae 525 Pfam PF02347 Glycine cleavage system P-protein 77 413 1.8E-10 T 14-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 TSH58p_22050 5cc4b10a8d349314971fc041571b7834 265 Gene3D G3DSA:3.10.20.10 35 120 8.6E-10 T 14-10-2018 TSH58p_22050 5cc4b10a8d349314971fc041571b7834 265 Gene3D G3DSA:3.40.140.10 126 265 5.7E-43 T 14-10-2018 TSH58p_22050 5cc4b10a8d349314971fc041571b7834 265 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 13 265 26.761 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 TSH58p_22050 5cc4b10a8d349314971fc041571b7834 265 PIRSF PIRSF015626 11 265 2.7E-69 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 TSH58p_22050 5cc4b10a8d349314971fc041571b7834 265 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 32 257 7.6E-50 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 TSH58p_22050 5cc4b10a8d349314971fc041571b7834 265 Pfam PF02634 FdhD/NarQ family 33 263 4.8E-69 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 TSH58p_22050 5cc4b10a8d349314971fc041571b7834 265 SUPERFAMILY SSF53927 26 264 3.91E-71 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TSH58p_14085 1538b4d63c8efc422122e686e793dd89 347 Gene3D G3DSA:3.40.630.10 37 346 7.5E-57 T 14-10-2018 TSH58p_14085 1538b4d63c8efc422122e686e793dd89 347 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 67 336 4.3E-15 T 14-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 TSH58p_14085 1538b4d63c8efc422122e686e793dd89 347 SUPERFAMILY SSF53187 38 344 7.63E-52 T 14-10-2018 TSH58p_06750 5f08ec09fa1b7167eb02bbd4577ed0fd 601 Gene3D G3DSA:1.20.140.70 32 180 1.5E-17 T 14-10-2018 TSH58p_06750 5f08ec09fa1b7167eb02bbd4577ed0fd 601 Gene3D G3DSA:1.10.1370.20 232 600 2.2E-113 T 14-10-2018 TSH58p_06750 5f08ec09fa1b7167eb02bbd4577ed0fd 601 Pfam PF01432 Peptidase family M3 345 587 1.3E-33 T 14-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 TSH58p_06750 5f08ec09fa1b7167eb02bbd4577ed0fd 601 Pfam PF08439 Oligopeptidase F 123 192 1.7E-20 T 14-10-2018 IPR013647 Oligopeptidase F, N-terminal domain TSH58p_06750 5f08ec09fa1b7167eb02bbd4577ed0fd 601 SUPERFAMILY SSF55486 18 586 8.96E-116 T 14-10-2018 TSH58p_06750 5f08ec09fa1b7167eb02bbd4577ed0fd 601 TIGRFAM TIGR02290 M3_fam_3: oligoendopeptidase, pepF/M3 family 20 599 1.1E-197 T 14-10-2018 IPR011977 Peptidase M3B, oligoendopeptidase-related clade 3 TSH58p_05765 d70175034b360a0f97546349b1a4fe09 309 Pfam PF00889 Elongation factor TS 71 289 3.8E-68 T 14-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 TSH58p_05765 d70175034b360a0f97546349b1a4fe09 309 SUPERFAMILY SSF46934 4 55 1.9E-19 T 14-10-2018 IPR009060 UBA-like superfamily GO:0005515 TSH58p_05765 d70175034b360a0f97546349b1a4fe09 309 Gene3D G3DSA:3.30.479.20 150 288 9.9E-44 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 TSH58p_05765 d70175034b360a0f97546349b1a4fe09 309 Gene3D G3DSA:3.30.479.20 57 147 4.9E-23 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 TSH58p_05765 d70175034b360a0f97546349b1a4fe09 309 Gene3D G3DSA:1.10.286.20 203 247 9.9E-44 T 14-10-2018 TSH58p_05765 d70175034b360a0f97546349b1a4fe09 309 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 14-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TSH58p_05765 d70175034b360a0f97546349b1a4fe09 309 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 14-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TSH58p_05765 d70175034b360a0f97546349b1a4fe09 309 SUPERFAMILY SSF54713 57 289 4.11E-47 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 TSH58p_05765 d70175034b360a0f97546349b1a4fe09 309 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 306 2.5E-94 T 14-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TSH58p_05765 d70175034b360a0f97546349b1a4fe09 309 Hamap MF_00050 Elongation factor Ts [tsf]. 1 306 77.238 T 14-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TSH58p_05765 d70175034b360a0f97546349b1a4fe09 309 Gene3D G3DSA:1.10.8.10 1 56 1.6E-28 T 14-10-2018 TSH58p_22090 04ccb7027afd32f0c844dd6b77d670fe 432 PIRSF PIRSF006809 7 430 4.8E-141 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 TSH58p_22090 04ccb7027afd32f0c844dd6b77d670fe 432 SUPERFAMILY SSF52540 197 378 1.14E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_22090 04ccb7027afd32f0c844dd6b77d670fe 432 Gene3D G3DSA:3.40.50.11060 15 136 4.0E-33 T 14-10-2018 TSH58p_22090 04ccb7027afd32f0c844dd6b77d670fe 432 Hamap MF_00900 GTPase HflX [hflX]. 25 399 46.051 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 TSH58p_22090 04ccb7027afd32f0c844dd6b77d670fe 432 Pfam PF13167 GTP-binding GTPase N-terminal 23 109 2.4E-24 T 14-10-2018 IPR025121 GTPase HflX, N-terminal TSH58p_22090 04ccb7027afd32f0c844dd6b77d670fe 432 Pfam PF01926 50S ribosome-binding GTPase 199 320 1.1E-18 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 TSH58p_22090 04ccb7027afd32f0c844dd6b77d670fe 432 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 220 238 1.5E-8 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 TSH58p_22090 04ccb7027afd32f0c844dd6b77d670fe 432 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 266 284 1.5E-8 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 TSH58p_22090 04ccb7027afd32f0c844dd6b77d670fe 432 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 199 219 1.5E-8 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 TSH58p_22090 04ccb7027afd32f0c844dd6b77d670fe 432 Gene3D G3DSA:3.40.50.300 197 374 3.7E-38 T 14-10-2018 TSH58p_22090 04ccb7027afd32f0c844dd6b77d670fe 432 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 19 369 1.2E-130 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 TSH58p_22090 04ccb7027afd32f0c844dd6b77d670fe 432 Pfam PF16360 GTP-binding GTPase Middle Region 112 191 7.2E-30 T 14-10-2018 IPR032305 GTP-binding protein, middle domain TSH58p_16110 a49b0a8ad69dac6c20be689b4d8f8a5c 532 Pfam PF00501 AMP-binding enzyme 18 424 3.4E-85 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_16110 a49b0a8ad69dac6c20be689b4d8f8a5c 532 ProSitePatterns PS00455 Putative AMP-binding domain signature. 177 188 - T 14-10-2018 IPR020845 AMP-binding, conserved site TSH58p_16110 a49b0a8ad69dac6c20be689b4d8f8a5c 532 SUPERFAMILY SSF56801 9 520 3.92E-123 T 14-10-2018 TSH58p_16110 a49b0a8ad69dac6c20be689b4d8f8a5c 532 Gene3D G3DSA:3.30.300.30 420 521 4.3E-22 T 14-10-2018 TSH58p_16110 a49b0a8ad69dac6c20be689b4d8f8a5c 532 Gene3D G3DSA:3.40.50.12780 3 419 3.6E-93 T 14-10-2018 TSH58p_16110 a49b0a8ad69dac6c20be689b4d8f8a5c 532 Pfam PF13193 AMP-binding enzyme C-terminal domain 433 510 5.8E-13 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSH58p_16070 5ff9dfeb7f0a5d41f19d284e9c70fe73 441 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 16 336 9.7E-57 T 14-10-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 TSH58p_16070 5ff9dfeb7f0a5d41f19d284e9c70fe73 441 Gene3D G3DSA:3.20.20.80 3 362 2.1E-112 T 14-10-2018 TSH58p_16070 5ff9dfeb7f0a5d41f19d284e9c70fe73 441 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 158 167 - T 14-10-2018 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 TSH58p_16070 5ff9dfeb7f0a5d41f19d284e9c70fe73 441 SUPERFAMILY SSF51445 5 360 4.7E-77 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_24635 64ea07ef1c3c097898fd6abdda167b12 428 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 235 272 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSH58p_24635 64ea07ef1c3c097898fd6abdda167b12 428 Gene3D G3DSA:3.90.1150.10 6 418 7.0E-167 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_24635 64ea07ef1c3c097898fd6abdda167b12 428 SUPERFAMILY SSF53383 18 425 1.38E-138 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_24635 64ea07ef1c3c097898fd6abdda167b12 428 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 9 423 3.9E-189 T 14-10-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 TSH58p_24635 64ea07ef1c3c097898fd6abdda167b12 428 Pfam PF00202 Aminotransferase class-III 21 421 2.2E-128 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSH58p_24635 64ea07ef1c3c097898fd6abdda167b12 428 PIRSF PIRSF000521 122 425 3.6E-41 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSH58p_24635 64ea07ef1c3c097898fd6abdda167b12 428 PIRSF PIRSF000521 18 127 0.0012 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSH58p_24635 64ea07ef1c3c097898fd6abdda167b12 428 Gene3D G3DSA:3.40.640.10 58 318 7.0E-167 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_14145 b4f1ef5c5e4efbba17621aa692df0ff3 402 Gene3D G3DSA:3.30.420.40 206 402 8.2E-73 T 14-10-2018 TSH58p_14145 b4f1ef5c5e4efbba17621aa692df0ff3 402 SUPERFAMILY SSF53067 170 398 1.18E-80 T 14-10-2018 TSH58p_14145 b4f1ef5c5e4efbba17621aa692df0ff3 402 SUPERFAMILY SSF53067 11 205 1.94E-58 T 14-10-2018 TSH58p_14145 b4f1ef5c5e4efbba17621aa692df0ff3 402 Hamap MF_00020 Acetate kinase [ackA]. 1 402 157.824 T 14-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_14145 b4f1ef5c5e4efbba17621aa692df0ff3 402 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 212 229 - T 14-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_14145 b4f1ef5c5e4efbba17621aa692df0ff3 402 PIRSF PIRSF000722 9 402 1.1E-137 T 14-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_14145 b4f1ef5c5e4efbba17621aa692df0ff3 402 PRINTS PR00471 Acetate kinase family signature 12 23 5.3E-40 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_14145 b4f1ef5c5e4efbba17621aa692df0ff3 402 PRINTS PR00471 Acetate kinase family signature 328 344 5.3E-40 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_14145 b4f1ef5c5e4efbba17621aa692df0ff3 402 PRINTS PR00471 Acetate kinase family signature 306 319 5.3E-40 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_14145 b4f1ef5c5e4efbba17621aa692df0ff3 402 PRINTS PR00471 Acetate kinase family signature 212 233 5.3E-40 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_14145 b4f1ef5c5e4efbba17621aa692df0ff3 402 PRINTS PR00471 Acetate kinase family signature 183 196 5.3E-40 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_14145 b4f1ef5c5e4efbba17621aa692df0ff3 402 PRINTS PR00471 Acetate kinase family signature 380 392 5.3E-40 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_14145 b4f1ef5c5e4efbba17621aa692df0ff3 402 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 12 23 - T 14-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_14145 b4f1ef5c5e4efbba17621aa692df0ff3 402 Pfam PF00871 Acetokinase family 12 392 3.3E-109 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_14145 b4f1ef5c5e4efbba17621aa692df0ff3 402 Gene3D G3DSA:3.30.420.40 2 204 1.0E-58 T 14-10-2018 TSH58p_14145 b4f1ef5c5e4efbba17621aa692df0ff3 402 TIGRFAM TIGR00016 ackA: acetate kinase 11 394 5.8E-110 T 14-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TSH58p_19535 13551f96d774124de28e7740bfbce99d 204 Gene3D G3DSA:3.40.50.850 3 204 4.0E-60 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TSH58p_19535 13551f96d774124de28e7740bfbce99d 204 SUPERFAMILY SSF52499 13 203 3.01E-48 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TSH58p_19535 13551f96d774124de28e7740bfbce99d 204 Pfam PF00857 Isochorismatase family 26 198 2.5E-36 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 TSH58p_26580 7c101031e5830aebc258b5dfa7d1a6dc 554 Gene3D G3DSA:3.40.50.300 330 547 1.4E-33 T 14-10-2018 TSH58p_26580 7c101031e5830aebc258b5dfa7d1a6dc 554 ProSitePatterns PS00211 ABC transporters family signature. 461 475 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_26580 7c101031e5830aebc258b5dfa7d1a6dc 554 SUPERFAMILY SSF90123 13 305 6.67E-13 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_26580 7c101031e5830aebc258b5dfa7d1a6dc 554 Gene3D G3DSA:1.20.1560.10 1 306 1.1E-6 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_26580 7c101031e5830aebc258b5dfa7d1a6dc 554 Pfam PF00005 ABC transporter 355 488 2.3E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_26580 7c101031e5830aebc258b5dfa7d1a6dc 554 SMART SM00382 361 537 4.7E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_26580 7c101031e5830aebc258b5dfa7d1a6dc 554 SUPERFAMILY SSF52540 335 544 1.25E-35 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_12890 0d01181476028d1aaabc80edbed0dfc3 336 SUPERFAMILY SSF103481 82 184 4.45E-9 T 14-10-2018 TSH58p_12890 0d01181476028d1aaabc80edbed0dfc3 336 SUPERFAMILY SSF103481 249 333 2.09E-6 T 14-10-2018 TSH58p_12890 0d01181476028d1aaabc80edbed0dfc3 336 Pfam PF00892 EamA-like transporter family 47 181 2.4E-11 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_31600 f1c9ba3e5aef91ec61824997db39907a 782 SUPERFAMILY SSF56935 64 782 5.29E-108 T 14-10-2018 TSH58p_31600 f1c9ba3e5aef91ec61824997db39907a 782 TIGRFAM TIGR01786 TonB-hemlactrns: TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein 75 782 3.8E-119 T 14-10-2018 IPR010949 TonB-dependent haemoglobin/transferrin/lactoferrin receptor GO:0019867|GO:0022857|GO:0055085 TSH58p_31600 f1c9ba3e5aef91ec61824997db39907a 782 Pfam PF07715 TonB-dependent Receptor Plug Domain 89 197 2.6E-23 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain TSH58p_31600 f1c9ba3e5aef91ec61824997db39907a 782 TIGRFAM TIGR01785 TonB-hemin: TonB-dependent heme/hemoglobin receptor family protein 72 782 2.5E-107 T 14-10-2018 IPR011276 TonB-dependent haem/haemoglobin receptor GO:0015232|GO:0015886|GO:0019867 TSH58p_31600 f1c9ba3e5aef91ec61824997db39907a 782 Gene3D G3DSA:2.170.130.10 89 212 1.0E-31 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily TSH58p_31600 f1c9ba3e5aef91ec61824997db39907a 782 Pfam PF00593 TonB dependent receptor 299 780 8.3E-55 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel TSH58p_31600 f1c9ba3e5aef91ec61824997db39907a 782 Gene3D G3DSA:2.40.170.20 216 782 4.1E-95 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily TSH58p_06620 3cd942d03daa8253c2abe747688eada4 151 Gene3D G3DSA:3.30.1460.30 35 136 2.3E-31 T 14-10-2018 TSH58p_06620 3cd942d03daa8253c2abe747688eada4 151 Pfam PF04993 TfoX N-terminal domain 45 135 2.6E-29 T 14-10-2018 IPR007076 TfoX, N-terminal TSH58p_06620 3cd942d03daa8253c2abe747688eada4 151 SUPERFAMILY SSF159894 37 136 2.56E-29 T 14-10-2018 TSH58p_18210 c491b272cbceacbd7f31ffe885b193f6 344 PRINTS PR01713 Nucleotide sugar epimerase signature 238 253 2.0E-6 T 14-10-2018 TSH58p_18210 c491b272cbceacbd7f31ffe885b193f6 344 PRINTS PR01713 Nucleotide sugar epimerase signature 261 276 2.0E-6 T 14-10-2018 TSH58p_18210 c491b272cbceacbd7f31ffe885b193f6 344 PRINTS PR01713 Nucleotide sugar epimerase signature 302 319 2.0E-6 T 14-10-2018 TSH58p_18210 c491b272cbceacbd7f31ffe885b193f6 344 Pfam PF01370 NAD dependent epimerase/dehydratase family 23 267 1.6E-41 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TSH58p_18210 c491b272cbceacbd7f31ffe885b193f6 344 Gene3D G3DSA:3.40.50.720 24 323 1.3E-72 T 14-10-2018 TSH58p_18210 c491b272cbceacbd7f31ffe885b193f6 344 SUPERFAMILY SSF51735 17 341 4.48E-75 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_18210 c491b272cbceacbd7f31ffe885b193f6 344 Gene3D G3DSA:3.90.25.10 199 335 1.3E-72 T 14-10-2018 TSH58p_23050 9ff6543fd14984bab53306b6e2e023bc 579 Gene3D G3DSA:3.10.105.10 323 542 6.6E-54 T 14-10-2018 TSH58p_23050 9ff6543fd14984bab53306b6e2e023bc 579 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 119 475 3.9E-92 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain TSH58p_23050 9ff6543fd14984bab53306b6e2e023bc 579 PIRSF PIRSF002741 39 575 3.4E-142 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TSH58p_23050 9ff6543fd14984bab53306b6e2e023bc 579 Gene3D G3DSA:3.40.190.10 64 319 2.3E-76 T 14-10-2018 TSH58p_23050 9ff6543fd14984bab53306b6e2e023bc 579 SUPERFAMILY SSF53850 72 563 1.7E-136 T 14-10-2018 TSH58p_03855 6f95b1c6b785d8e518971dddc8ebf5ff 170 Gene3D G3DSA:3.10.129.10 23 165 3.4E-18 T 14-10-2018 TSH58p_03855 6f95b1c6b785d8e518971dddc8ebf5ff 170 SUPERFAMILY SSF54637 27 163 3.24E-24 T 14-10-2018 IPR029069 HotDog domain superfamily TSH58p_03855 6f95b1c6b785d8e518971dddc8ebf5ff 170 Pfam PF13279 Thioesterase-like superfamily 32 163 2.7E-25 T 14-10-2018 TSH58p_18850 2dbc0c180415f9ff13c65303d0891008 268 TIGRFAM TIGR01581 Mo_ABC_porter: NifC-like ABC-type porter 25 244 9.8E-69 T 14-10-2018 IPR006469 NifC-like ABC-type porter GO:0005215|GO:0016020|GO:0055085 TSH58p_18850 2dbc0c180415f9ff13c65303d0891008 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 65 253 4.7E-21 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_18850 2dbc0c180415f9ff13c65303d0891008 268 Gene3D G3DSA:1.10.3720.10 1 257 2.3E-58 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_18850 2dbc0c180415f9ff13c65303d0891008 268 SUPERFAMILY SSF161098 6 248 2.8E-47 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_23750 79292f586228e2b924f45df7591a1cae 341 Pfam PF01548 Transposase 7 147 8.6E-13 T 14-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 TSH58p_23750 79292f586228e2b924f45df7591a1cae 341 Pfam PF02371 Transposase IS116/IS110/IS902 family 212 289 2.4E-26 T 14-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 TSH58p_31365 610a69d90dd5bcf15c1225ad40177bcd 267 SUPERFAMILY SSF46785 27 87 3.39E-6 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_31365 610a69d90dd5bcf15c1225ad40177bcd 267 Gene3D G3DSA:1.10.10.10 8 107 1.6E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_31365 610a69d90dd5bcf15c1225ad40177bcd 267 Pfam PF13730 Helix-turn-helix domain 28 75 4.0E-11 T 14-10-2018 TSH58p_07380 e6fd6b3fb26f8d6d75466725aea52605 160 SUPERFAMILY SSF46785 2 135 4.63E-36 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_07380 e6fd6b3fb26f8d6d75466725aea52605 160 Pfam PF02082 Transcriptional regulator 1 83 2.2E-27 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type TSH58p_07380 e6fd6b3fb26f8d6d75466725aea52605 160 Gene3D G3DSA:1.10.10.10 1 142 6.9E-49 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_07380 e6fd6b3fb26f8d6d75466725aea52605 160 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 133 7.6E-43 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type TSH58p_07380 e6fd6b3fb26f8d6d75466725aea52605 160 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 14-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site TSH58p_24900 29fc7012b8c9f1657b5043d01bf314da 98 Pfam PF00550 Phosphopantetheine attachment site 32 88 1.9E-5 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain TSH58p_24900 29fc7012b8c9f1657b5043d01bf314da 98 SUPERFAMILY SSF47336 18 92 1.58E-10 T 14-10-2018 IPR036736 ACP-like superfamily TSH58p_24900 29fc7012b8c9f1657b5043d01bf314da 98 Gene3D G3DSA:1.10.1200.10 14 95 5.0E-23 T 14-10-2018 IPR036736 ACP-like superfamily TSH58p_03860 83233cdc2a10d80ec354f25c58c6f530 294 Pfam PF13468 Glyoxalase-like domain 9 193 3.1E-35 T 14-10-2018 IPR025870 Glyoxalase-like domain TSH58p_03860 83233cdc2a10d80ec354f25c58c6f530 294 SUPERFAMILY SSF54593 3 259 2.03E-21 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSH58p_03860 83233cdc2a10d80ec354f25c58c6f530 294 Gene3D G3DSA:3.10.180.10 5 158 3.9E-11 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSH58p_25950 a7bcfb055aa581fedc53718140c95285 264 Gene3D G3DSA:2.40.33.20 134 263 2.4E-17 T 14-10-2018 TSH58p_25950 a7bcfb055aa581fedc53718140c95285 264 SUPERFAMILY SSF50800 1 257 2.2E-24 T 14-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily TSH58p_25950 a7bcfb055aa581fedc53718140c95285 264 Pfam PF03473 MOSC domain 141 256 2.1E-16 T 14-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 TSH58p_25950 a7bcfb055aa581fedc53718140c95285 264 Pfam PF03476 MOSC N-terminal beta barrel domain 3 97 4.6E-6 T 14-10-2018 IPR005303 MOSC, N-terminal beta barrel KEGG: 00790+2.8.1.9|MetaCyc: PWY-5963 TSH58p_30920 5a2434f19fbcaa7d268a8ea9a0cf376e 284 Gene3D G3DSA:1.10.3720.10 84 277 1.2E-25 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_30920 5a2434f19fbcaa7d268a8ea9a0cf376e 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 262 1.1E-23 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_30920 5a2434f19fbcaa7d268a8ea9a0cf376e 284 SUPERFAMILY SSF161098 88 266 2.75E-33 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_30455 1b8f5290a7d4c84eb89dbc61ae6af477 416 TIGRFAM TIGR01373 soxB: sarcosine oxidase, beta subunit family 3 408 7.6E-203 T 14-10-2018 IPR006278 Sarcosine oxidase subunit beta GO:0008115|GO:0046653|GO:0055114 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 TSH58p_30455 1b8f5290a7d4c84eb89dbc61ae6af477 416 Pfam PF01266 FAD dependent oxidoreductase 34 380 4.8E-58 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TSH58p_30455 1b8f5290a7d4c84eb89dbc61ae6af477 416 SUPERFAMILY SSF51905 33 405 2.93E-53 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_30455 1b8f5290a7d4c84eb89dbc61ae6af477 416 Gene3D G3DSA:3.50.50.60 34 389 2.6E-110 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_30455 1b8f5290a7d4c84eb89dbc61ae6af477 416 Gene3D G3DSA:3.30.9.10 115 346 2.6E-110 T 14-10-2018 TSH58p_25765 607afe80ba83fefd648f26d3a4b4d365 482 PIRSF PIRSF009414 11 479 9.3E-73 T 14-10-2018 IPR008670 Long-chain-fatty-acyl-CoA reductase, LuxC GO:0003995|GO:0008218|GO:0055114 KEGG: 00073+1.2.1.50|MetaCyc: PWY-7723 TSH58p_25765 607afe80ba83fefd648f26d3a4b4d365 482 SUPERFAMILY SSF53720 162 360 7.63E-5 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSH58p_25765 607afe80ba83fefd648f26d3a4b4d365 482 Pfam PF05893 Acyl-CoA reductase (LuxC) 60 462 5.8E-91 T 14-10-2018 IPR008670 Long-chain-fatty-acyl-CoA reductase, LuxC GO:0003995|GO:0008218|GO:0055114 KEGG: 00073+1.2.1.50|MetaCyc: PWY-7723 TSH58p_08830 0232499b4422121b4a0ef890693cb8e8 624 SUPERFAMILY SSF55874 444 608 8.25E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_08830 0232499b4422121b4a0ef890693cb8e8 624 Gene3D G3DSA:3.30.565.10 455 611 4.9E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_08830 0232499b4422121b4a0ef890693cb8e8 624 Gene3D G3DSA:3.30.450.350 110 321 1.4E-49 T 14-10-2018 TSH58p_08830 0232499b4422121b4a0ef890693cb8e8 624 Pfam PF00512 His Kinase A (phospho-acceptor) domain 390 455 1.2E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_08830 0232499b4422121b4a0ef890693cb8e8 624 Gene3D G3DSA:1.10.287.130 355 453 1.6E-17 T 14-10-2018 TSH58p_08830 0232499b4422121b4a0ef890693cb8e8 624 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 500 609 6.9E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_08830 0232499b4422121b4a0ef890693cb8e8 624 Pfam PF03924 CHASE domain 109 297 2.1E-64 T 14-10-2018 IPR006189 CHASE domain TSH58p_08830 0232499b4422121b4a0ef890693cb8e8 624 SMART SM00388 390 455 5.1E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_08830 0232499b4422121b4a0ef890693cb8e8 624 PRINTS PR00344 Bacterial sensor protein C-terminal signature 594 607 6.5E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_08830 0232499b4422121b4a0ef890693cb8e8 624 PRINTS PR00344 Bacterial sensor protein C-terminal signature 570 588 6.5E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_08830 0232499b4422121b4a0ef890693cb8e8 624 PRINTS PR00344 Bacterial sensor protein C-terminal signature 553 563 6.5E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_08830 0232499b4422121b4a0ef890693cb8e8 624 PRINTS PR00344 Bacterial sensor protein C-terminal signature 535 549 6.5E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_08830 0232499b4422121b4a0ef890693cb8e8 624 SMART SM00387 499 610 4.2E-28 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_08830 0232499b4422121b4a0ef890693cb8e8 624 SUPERFAMILY SSF47384 374 455 4.32E-15 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_08830 0232499b4422121b4a0ef890693cb8e8 624 SMART SM01079 106 299 8.1E-78 T 14-10-2018 IPR006189 CHASE domain TSH58p_11810 d1035663a5beceea9091a7e9ce5ff574 397 SUPERFAMILY SSF47384 151 236 1.35E-21 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_11810 d1035663a5beceea9091a7e9ce5ff574 397 Pfam PF00512 His Kinase A (phospho-acceptor) domain 167 235 4.0E-18 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_11810 d1035663a5beceea9091a7e9ce5ff574 397 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 282 393 3.0E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_11810 d1035663a5beceea9091a7e9ce5ff574 397 SMART SM00388 166 235 4.7E-21 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_11810 d1035663a5beceea9091a7e9ce5ff574 397 SUPERFAMILY SSF54631 34 141 5.68E-7 T 14-10-2018 TSH58p_11810 d1035663a5beceea9091a7e9ce5ff574 397 SMART SM00387 281 394 7.6E-33 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_11810 d1035663a5beceea9091a7e9ce5ff574 397 Gene3D G3DSA:1.10.287.130 137 233 6.0E-27 T 14-10-2018 TSH58p_11810 d1035663a5beceea9091a7e9ce5ff574 397 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 391 1.3E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_11810 d1035663a5beceea9091a7e9ce5ff574 397 PRINTS PR00344 Bacterial sensor protein C-terminal signature 354 372 1.3E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_11810 d1035663a5beceea9091a7e9ce5ff574 397 PRINTS PR00344 Bacterial sensor protein C-terminal signature 319 333 1.3E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_11810 d1035663a5beceea9091a7e9ce5ff574 397 Gene3D G3DSA:3.30.565.10 234 395 2.1E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_11810 d1035663a5beceea9091a7e9ce5ff574 397 SUPERFAMILY SSF55874 224 392 7.07E-41 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_05535 8b8929db19837d0edc4d070c61f733fd 425 Gene3D G3DSA:3.20.20.120 128 425 5.6E-130 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TSH58p_05535 8b8929db19837d0edc4d070c61f733fd 425 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 421 2.6E-205 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_05535 8b8929db19837d0edc4d070c61f733fd 425 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 423 2.1E-129 T 14-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_05535 8b8929db19837d0edc4d070c61f733fd 425 ProSitePatterns PS00164 Enolase signature. 334 347 - T 14-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_05535 8b8929db19837d0edc4d070c61f733fd 425 SUPERFAMILY SSF54826 3 138 8.17E-55 T 14-10-2018 TSH58p_05535 8b8929db19837d0edc4d070c61f733fd 425 Hamap MF_00318 Enolase [eno]. 2 411 44.652 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_05535 8b8929db19837d0edc4d070c61f733fd 425 SMART SM01193 4 134 8.8E-94 T 14-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_05535 8b8929db19837d0edc4d070c61f733fd 425 SMART SM01192 139 425 8.0E-220 T 14-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_05535 8b8929db19837d0edc4d070c61f733fd 425 Gene3D G3DSA:3.30.390.10 1 127 1.3E-56 T 14-10-2018 IPR029017 Enolase-like, N-terminal TSH58p_05535 8b8929db19837d0edc4d070c61f733fd 425 PIRSF PIRSF001400 1 425 1.7E-185 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_05535 8b8929db19837d0edc4d070c61f733fd 425 SUPERFAMILY SSF51604 141 422 1.41E-126 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TSH58p_05535 8b8929db19837d0edc4d070c61f733fd 425 Pfam PF03952 Enolase, N-terminal domain 4 134 1.0E-58 T 14-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_05535 8b8929db19837d0edc4d070c61f733fd 425 PRINTS PR00148 Enolase signature 37 51 2.2E-48 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_05535 8b8929db19837d0edc4d070c61f733fd 425 PRINTS PR00148 Enolase signature 363 380 2.2E-48 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_05535 8b8929db19837d0edc4d070c61f733fd 425 PRINTS PR00148 Enolase signature 107 123 2.2E-48 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_05535 8b8929db19837d0edc4d070c61f733fd 425 PRINTS PR00148 Enolase signature 161 174 2.2E-48 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_05535 8b8929db19837d0edc4d070c61f733fd 425 PRINTS PR00148 Enolase signature 311 322 2.2E-48 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_05535 8b8929db19837d0edc4d070c61f733fd 425 PRINTS PR00148 Enolase signature 334 348 2.2E-48 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_01870 1d261e3c02c608c5ce7f4927ff3905d6 675 SMART SM00283 415 669 1.3E-41 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_01870 1d261e3c02c608c5ce7f4927ff3905d6 675 Gene3D G3DSA:1.20.1480.50 285 382 3.2E-16 T 14-10-2018 TSH58p_01870 1d261e3c02c608c5ce7f4927ff3905d6 675 SMART SM01358 43 296 3.9E-24 T 14-10-2018 IPR032255 Helical bimodular sensor domain TSH58p_01870 1d261e3c02c608c5ce7f4927ff3905d6 675 Pfam PF00672 HAMP domain 325 374 1.0E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_01870 1d261e3c02c608c5ce7f4927ff3905d6 675 SUPERFAMILY SSF58104 352 668 1.83E-58 T 14-10-2018 TSH58p_01870 1d261e3c02c608c5ce7f4927ff3905d6 675 SMART SM00304 325 378 1.7E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_01870 1d261e3c02c608c5ce7f4927ff3905d6 675 Gene3D G3DSA:1.10.287.950 383 673 1.6E-51 T 14-10-2018 TSH58p_01870 1d261e3c02c608c5ce7f4927ff3905d6 675 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 484 640 4.5E-33 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_08350 20f1a7fb4b6eb39577e832e03ccb1967 280 SUPERFAMILY SSF52540 17 251 6.34E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_08350 20f1a7fb4b6eb39577e832e03ccb1967 280 Gene3D G3DSA:3.40.50.300 14 255 1.5E-60 T 14-10-2018 TSH58p_08350 20f1a7fb4b6eb39577e832e03ccb1967 280 SMART SM00382 44 233 7.1E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_08350 20f1a7fb4b6eb39577e832e03ccb1967 280 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_08350 20f1a7fb4b6eb39577e832e03ccb1967 280 Pfam PF00005 ABC transporter 35 182 6.4E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_32305 b5f5033a4a9f021e8cb38a0a58fb6c36 792 Pfam PF13802 Galactose mutarotase-like 165 235 4.9E-18 T 14-10-2018 IPR025887 Glycoside hydrolase family 31, N-terminal domain TSH58p_32305 b5f5033a4a9f021e8cb38a0a58fb6c36 792 Gene3D G3DSA:2.60.40.1180 651 702 2.0E-11 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta TSH58p_32305 b5f5033a4a9f021e8cb38a0a58fb6c36 792 Pfam PF01055 Glycosyl hydrolases family 31 260 705 6.8E-101 T 14-10-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 TSH58p_32305 b5f5033a4a9f021e8cb38a0a58fb6c36 792 Gene3D G3DSA:3.20.20.80 266 650 8.3E-102 T 14-10-2018 TSH58p_32305 b5f5033a4a9f021e8cb38a0a58fb6c36 792 SUPERFAMILY SSF51011 620 701 1.65E-20 T 14-10-2018 TSH58p_32305 b5f5033a4a9f021e8cb38a0a58fb6c36 792 SUPERFAMILY SSF51445 269 617 2.69E-58 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_32305 b5f5033a4a9f021e8cb38a0a58fb6c36 792 Gene3D G3DSA:2.60.40.1760 63 264 4.8E-35 T 14-10-2018 TSH58p_32305 b5f5033a4a9f021e8cb38a0a58fb6c36 792 SUPERFAMILY SSF74650 24 266 1.35E-35 T 14-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 TSH58p_31210 d739a9ef6fca8c85726e451b1d68695f 123 SUPERFAMILY SSF46626 16 120 5.38E-12 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_31210 d739a9ef6fca8c85726e451b1d68695f 123 Gene3D G3DSA:1.10.760.10 8 122 1.4E-11 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_31210 d739a9ef6fca8c85726e451b1d68695f 123 Pfam PF00034 Cytochrome c 39 119 1.7E-5 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_00960 139ab665934195cc5ff93c6a1a565d29 109 Pfam PF00550 Phosphopantetheine attachment site 36 89 6.8E-7 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain TSH58p_00960 139ab665934195cc5ff93c6a1a565d29 109 SUPERFAMILY SSF47336 26 101 6.15E-13 T 14-10-2018 IPR036736 ACP-like superfamily TSH58p_00960 139ab665934195cc5ff93c6a1a565d29 109 Gene3D G3DSA:1.10.1200.10 24 101 2.7E-16 T 14-10-2018 IPR036736 ACP-like superfamily TSH58p_08205 7ef06a1996f7d91376b099db5f618002 631 SUPERFAMILY SSF54211 208 330 1.78E-34 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSH58p_08205 7ef06a1996f7d91376b099db5f618002 631 SUPERFAMILY SSF55874 1 199 6.94E-52 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_08205 7ef06a1996f7d91376b099db5f618002 631 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 1 310 9.6E-90 T 14-10-2018 IPR002099 DNA mismatch repair protein family, N-terminal GO:0005524|GO:0006298|GO:0030983 TSH58p_08205 7ef06a1996f7d91376b099db5f618002 631 Gene3D G3DSA:3.30.230.10 217 329 8.6E-34 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSH58p_08205 7ef06a1996f7d91376b099db5f618002 631 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 1 628 28.055 T 14-10-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 TSH58p_08205 7ef06a1996f7d91376b099db5f618002 631 SMART SM01340 212 330 1.7E-56 T 14-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 TSH58p_08205 7ef06a1996f7d91376b099db5f618002 631 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 24 125 4.5E-11 T 14-10-2018 TSH58p_08205 7ef06a1996f7d91376b099db5f618002 631 SUPERFAMILY SSF118116 440 630 3.79E-60 T 14-10-2018 IPR037198 MutL, C-terminal domain superfamily TSH58p_08205 7ef06a1996f7d91376b099db5f618002 631 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 92 98 - T 14-10-2018 IPR014762 DNA mismatch repair, conserved site TSH58p_08205 7ef06a1996f7d91376b099db5f618002 631 Gene3D G3DSA:2.30.42.20 447 625 3.6E-57 T 14-10-2018 TSH58p_08205 7ef06a1996f7d91376b099db5f618002 631 Gene3D G3DSA:3.30.1370.100 488 583 3.6E-57 T 14-10-2018 TSH58p_08205 7ef06a1996f7d91376b099db5f618002 631 Gene3D G3DSA:3.30.565.10 1 208 6.5E-64 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_08205 7ef06a1996f7d91376b099db5f618002 631 Pfam PF08676 MutL C terminal dimerisation domain 441 588 4.7E-48 T 14-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 TSH58p_08205 7ef06a1996f7d91376b099db5f618002 631 SMART SM00853 445 588 9.9E-54 T 14-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 TSH58p_08205 7ef06a1996f7d91376b099db5f618002 631 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 214 329 2.8E-36 T 14-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 TSH58p_20125 8fd3d2cc4af4f0d66acb41a9d709d752 261 SUPERFAMILY SSF117143 93 222 2.75E-33 T 14-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like TSH58p_20125 8fd3d2cc4af4f0d66acb41a9d709d752 261 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 136 1.4E-46 T 14-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G TSH58p_20125 8fd3d2cc4af4f0d66acb41a9d709d752 261 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 143 243 1.5E-29 T 14-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G TSH58p_20125 8fd3d2cc4af4f0d66acb41a9d709d752 261 TIGRFAM TIGR02488 flgG_G_neg: flagellar basal-body rod protein FlgG 4 260 8.6E-107 T 14-10-2018 IPR012834 Flagellar basal-body rod FlgG GO:0009426|GO:0071973 TSH58p_20125 8fd3d2cc4af4f0d66acb41a9d709d752 261 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 10 30 - T 14-10-2018 IPR019776 Flagellar basal body rod protein, conserved site TSH58p_20125 8fd3d2cc4af4f0d66acb41a9d709d752 261 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 182 260 1.9E-26 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain TSH58p_20125 8fd3d2cc4af4f0d66acb41a9d709d752 261 Pfam PF00460 Flagella basal body rod protein 4 34 1.1E-10 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 TSH58p_24385 b769b964fd45168503a005ccebf64fd1 234 Pfam PF01048 Phosphorylase superfamily 30 154 4.0E-14 T 14-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TSH58p_24385 b769b964fd45168503a005ccebf64fd1 234 SUPERFAMILY SSF53167 1 155 4.45E-20 T 14-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TSH58p_24385 b769b964fd45168503a005ccebf64fd1 234 Gene3D G3DSA:3.40.50.1580 4 171 1.7E-17 T 14-10-2018 TSH58p_06240 bfb0f90637e3df586f2fd9a8f74aa8d9 577 SMART SM00091 37 103 32.0 T 14-10-2018 IPR000014 PAS domain TSH58p_06240 bfb0f90637e3df586f2fd9a8f74aa8d9 577 SMART SM00091 178 246 0.0035 T 14-10-2018 IPR000014 PAS domain TSH58p_06240 bfb0f90637e3df586f2fd9a8f74aa8d9 577 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 459 567 1.4E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_06240 bfb0f90637e3df586f2fd9a8f74aa8d9 577 PRINTS PR00344 Bacterial sensor protein C-terminal signature 498 512 1.5E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_06240 bfb0f90637e3df586f2fd9a8f74aa8d9 577 PRINTS PR00344 Bacterial sensor protein C-terminal signature 554 567 1.5E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_06240 bfb0f90637e3df586f2fd9a8f74aa8d9 577 PRINTS PR00344 Bacterial sensor protein C-terminal signature 516 526 1.5E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_06240 bfb0f90637e3df586f2fd9a8f74aa8d9 577 PRINTS PR00344 Bacterial sensor protein C-terminal signature 529 547 1.5E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_06240 bfb0f90637e3df586f2fd9a8f74aa8d9 577 SUPERFAMILY SSF47384 326 397 1.33E-5 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_06240 bfb0f90637e3df586f2fd9a8f74aa8d9 577 Pfam PF08447 PAS fold 203 288 9.0E-10 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 TSH58p_06240 bfb0f90637e3df586f2fd9a8f74aa8d9 577 SUPERFAMILY SSF55785 21 77 9.72E-11 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_06240 bfb0f90637e3df586f2fd9a8f74aa8d9 577 Pfam PF00512 His Kinase A (phospho-acceptor) domain 331 407 1.5E-6 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_06240 bfb0f90637e3df586f2fd9a8f74aa8d9 577 SUPERFAMILY SSF55874 406 572 3.67E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_06240 bfb0f90637e3df586f2fd9a8f74aa8d9 577 Gene3D G3DSA:3.30.450.20 25 173 8.1E-13 T 14-10-2018 TSH58p_06240 bfb0f90637e3df586f2fd9a8f74aa8d9 577 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 176 301 6.4E-9 T 14-10-2018 IPR000014 PAS domain TSH58p_06240 bfb0f90637e3df586f2fd9a8f74aa8d9 577 SMART SM00388 331 415 0.0065 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_06240 bfb0f90637e3df586f2fd9a8f74aa8d9 577 Gene3D G3DSA:3.30.450.20 174 291 4.0E-20 T 14-10-2018 TSH58p_06240 bfb0f90637e3df586f2fd9a8f74aa8d9 577 SMART SM00387 457 570 9.8E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_06240 bfb0f90637e3df586f2fd9a8f74aa8d9 577 SUPERFAMILY SSF55785 163 293 5.06E-20 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_06240 bfb0f90637e3df586f2fd9a8f74aa8d9 577 SMART SM00086 253 295 0.0011 T 14-10-2018 IPR001610 PAC motif TSH58p_06240 bfb0f90637e3df586f2fd9a8f74aa8d9 577 Gene3D G3DSA:1.10.287.130 307 409 1.0E-20 T 14-10-2018 TSH58p_06240 bfb0f90637e3df586f2fd9a8f74aa8d9 577 Pfam PF12860 PAS fold 44 170 1.9E-19 T 14-10-2018 TSH58p_06240 bfb0f90637e3df586f2fd9a8f74aa8d9 577 Gene3D G3DSA:3.30.565.10 414 573 1.2E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_01805 56a24b70c9987d3b286f72cf16e5f916 266 TIGRFAM TIGR02017 hutG_amidohyd: N-formylglutamate deformylase 5 264 4.5E-108 T 14-10-2018 IPR010247 N-formylglutamate deformylase TSH58p_01805 56a24b70c9987d3b286f72cf16e5f916 266 Gene3D G3DSA:3.40.630.40 2 265 1.9E-72 T 14-10-2018 TSH58p_01805 56a24b70c9987d3b286f72cf16e5f916 266 Pfam PF05013 N-formylglutamate amidohydrolase 12 231 8.0E-68 T 14-10-2018 IPR007709 N-formylglutamate amidohydrolase TSH58p_01805 56a24b70c9987d3b286f72cf16e5f916 266 SUPERFAMILY SSF53187 3 264 2.29E-81 T 14-10-2018 TSH58p_28780 b54a7d1ba8cc5e44397ad1528db6cdd5 189 SUPERFAMILY SSF50346 73 175 5.3E-8 T 14-10-2018 IPR011033 PRC-barrel-like superfamily TSH58p_28780 b54a7d1ba8cc5e44397ad1528db6cdd5 189 Pfam PF05239 PRC-barrel domain 86 141 1.9E-5 T 14-10-2018 IPR027275 PRC-barrel domain TSH58p_15950 422e52bac297662c3ba6d513e5da4ddd 294 SUPERFAMILY SSF88659 190 287 4.3E-21 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSH58p_15950 422e52bac297662c3ba6d513e5da4ddd 294 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 48 282 5.8E-32 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TSH58p_15950 422e52bac297662c3ba6d513e5da4ddd 294 Pfam PF00140 Sigma-70 factor, region 1.2 17 43 3.7E-8 T 14-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_15950 422e52bac297662c3ba6d513e5da4ddd 294 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 15 284 3.7E-111 T 14-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_15950 422e52bac297662c3ba6d513e5da4ddd 294 PRINTS PR00046 Major sigma-70 factor signature 253 268 5.5E-22 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_15950 422e52bac297662c3ba6d513e5da4ddd 294 PRINTS PR00046 Major sigma-70 factor signature 77 90 5.5E-22 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_15950 422e52bac297662c3ba6d513e5da4ddd 294 PRINTS PR00046 Major sigma-70 factor signature 234 246 5.5E-22 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_15950 422e52bac297662c3ba6d513e5da4ddd 294 PRINTS PR00046 Major sigma-70 factor signature 101 109 5.5E-22 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_15950 422e52bac297662c3ba6d513e5da4ddd 294 PRINTS PR00046 Major sigma-70 factor signature 268 279 5.5E-22 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_15950 422e52bac297662c3ba6d513e5da4ddd 294 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 253 279 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_15950 422e52bac297662c3ba6d513e5da4ddd 294 Gene3D G3DSA:1.10.10.10 214 288 8.7E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_15950 422e52bac297662c3ba6d513e5da4ddd 294 Pfam PF04545 Sigma-70, region 4 230 281 1.6E-16 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 TSH58p_15950 422e52bac297662c3ba6d513e5da4ddd 294 Pfam PF04542 Sigma-70 region 2 53 118 9.7E-17 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_15950 422e52bac297662c3ba6d513e5da4ddd 294 PIRSF PIRSF000770 1 293 7.1E-38 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_15950 422e52bac297662c3ba6d513e5da4ddd 294 Gene3D G3DSA:1.10.601.10 9 120 7.1E-32 T 14-10-2018 TSH58p_15950 422e52bac297662c3ba6d513e5da4ddd 294 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 1 285 51.302 T 14-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_15950 422e52bac297662c3ba6d513e5da4ddd 294 SUPERFAMILY SSF88946 11 121 3.45E-40 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_08060 5c312dd03f5f483ca012f54970df6c82 370 Gene3D G3DSA:3.30.1540.10 224 311 1.0E-99 T 14-10-2018 TSH58p_08060 5c312dd03f5f483ca012f54970df6c82 370 Pfam PF02515 CoA-transferase family III 6 336 4.1E-96 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 TSH58p_08060 5c312dd03f5f483ca012f54970df6c82 370 SUPERFAMILY SSF89796 5 334 2.35E-99 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily TSH58p_08060 5c312dd03f5f483ca012f54970df6c82 370 Gene3D G3DSA:3.40.50.10540 6 328 1.0E-99 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily TSH58p_15500 ff4b073a4a94679a4f6460786c483e66 106 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 6.7E-14 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 TSH58p_15500 ff4b073a4a94679a4f6460786c483e66 106 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 6.7E-14 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 TSH58p_15500 ff4b073a4a94679a4f6460786c483e66 106 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 6.7E-14 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 TSH58p_15500 ff4b073a4a94679a4f6460786c483e66 106 Pfam PF01313 Bacterial export proteins, family 3 6 77 1.6E-23 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 TSH58p_13685 7fac5e11b1d1b7c11fe1a46d70c9c348 420 Pfam PF04748 Divergent polysaccharide deacetylase 201 414 1.4E-66 T 14-10-2018 IPR006837 Divergent polysaccharide deacetylase TSH58p_13685 7fac5e11b1d1b7c11fe1a46d70c9c348 420 SUPERFAMILY SSF88713 196 414 6.67E-60 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TSH58p_13685 7fac5e11b1d1b7c11fe1a46d70c9c348 420 Gene3D G3DSA:3.20.20.370 181 420 8.9E-87 T 14-10-2018 TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 Gene3D G3DSA:3.40.50.2300 938 1064 3.6E-18 T 14-10-2018 TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 PRINTS PR00344 Bacterial sensor protein C-terminal signature 849 863 3.3E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 PRINTS PR00344 Bacterial sensor protein C-terminal signature 884 902 3.3E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 PRINTS PR00344 Bacterial sensor protein C-terminal signature 908 921 3.3E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 PRINTS PR00344 Bacterial sensor protein C-terminal signature 867 877 3.3E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 Pfam PF08448 PAS fold 326 423 2.6E-7 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 814 922 2.4E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 SUPERFAMILY SSF55785 420 551 9.77E-18 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 Gene3D G3DSA:3.30.450.20 560 634 3.6E-18 T 14-10-2018 TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 Gene3D G3DSA:3.30.450.20 431 502 4.7E-19 T 14-10-2018 TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 SUPERFAMILY SSF52172 947 1063 1.24E-19 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 SUPERFAMILY SSF55785 305 409 2.09E-9 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 Gene3D G3DSA:3.30.450.20 311 422 2.5E-19 T 14-10-2018 TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 Pfam PF00072 Response regulator receiver domain 947 1059 4.0E-11 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 SUPERFAMILY SSF55785 550 680 4.36E-19 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 Pfam PF08447 PAS fold 588 675 2.7E-13 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 Pfam PF08447 PAS fold 459 546 4.2E-16 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 SMART SM00387 813 924 4.1E-30 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 Gene3D G3DSA:2.10.70.100 637 679 6.3E-10 T 14-10-2018 TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 Gene3D G3DSA:2.10.70.100 509 555 2.5E-16 T 14-10-2018 TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 Gene3D G3DSA:1.10.287.130 680 765 3.2E-16 T 14-10-2018 TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 SMART SM00448 944 1058 3.2E-11 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 SUPERFAMILY SSF47384 686 767 4.71E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 431 559 3.3E-6 T 14-10-2018 IPR000014 PAS domain TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 SMART SM00091 435 503 6.7 T 14-10-2018 IPR000014 PAS domain TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 SMART SM00091 319 384 0.014 T 14-10-2018 IPR000014 PAS domain TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 SMART SM00091 565 633 1.7E-4 T 14-10-2018 IPR000014 PAS domain TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 SUPERFAMILY SSF55874 756 922 4.98E-41 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 Gene3D G3DSA:3.30.565.10 767 925 1.3E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 SMART SM00086 640 682 3.3E-4 T 14-10-2018 IPR001610 PAC motif TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 SMART SM00086 511 553 7.4E-10 T 14-10-2018 IPR001610 PAC motif TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 Gene3D G3DSA:3.30.450.20 37 179 1.4E-14 T 14-10-2018 TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 SMART SM00388 702 767 7.3E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_32075 26a6ada003adc5ecd80be69bf567cbc5 1064 Pfam PF00512 His Kinase A (phospho-acceptor) domain 702 765 2.7E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_15715 1301bdf690fd6ebcbc4d50e81277e9e7 653 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 415 651 3.9E-120 T 14-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 TSH58p_15715 1301bdf690fd6ebcbc4d50e81277e9e7 653 Gene3D G3DSA:1.10.10.10 492 567 4.3E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_15715 1301bdf690fd6ebcbc4d50e81277e9e7 653 Gene3D G3DSA:1.10.220.120 29 85 4.5E-23 T 14-10-2018 TSH58p_15715 1301bdf690fd6ebcbc4d50e81277e9e7 653 SUPERFAMILY SSF88946 130 486 2.04E-97 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_15715 1301bdf690fd6ebcbc4d50e81277e9e7 653 Pfam PF03979 Sigma-70 factor, region 1.1 30 89 1.1E-22 T 14-10-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 TSH58p_15715 1301bdf690fd6ebcbc4d50e81277e9e7 653 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 415 640 3.7E-39 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TSH58p_15715 1301bdf690fd6ebcbc4d50e81277e9e7 653 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 12 652 43.864 T 14-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 TSH58p_15715 1301bdf690fd6ebcbc4d50e81277e9e7 653 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 612 638 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_15715 1301bdf690fd6ebcbc4d50e81277e9e7 653 Pfam PF04539 Sigma-70 region 3 498 573 2.5E-29 T 14-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 TSH58p_15715 1301bdf690fd6ebcbc4d50e81277e9e7 653 SUPERFAMILY SSF88659 492 565 1.87E-20 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSH58p_15715 1301bdf690fd6ebcbc4d50e81277e9e7 653 Pfam PF00140 Sigma-70 factor, region 1.2 113 145 1.2E-13 T 14-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_15715 1301bdf690fd6ebcbc4d50e81277e9e7 653 PRINTS PR00046 Major sigma-70 factor signature 443 456 3.4E-31 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_15715 1301bdf690fd6ebcbc4d50e81277e9e7 653 PRINTS PR00046 Major sigma-70 factor signature 591 603 3.4E-31 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_15715 1301bdf690fd6ebcbc4d50e81277e9e7 653 PRINTS PR00046 Major sigma-70 factor signature 627 638 3.4E-31 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_15715 1301bdf690fd6ebcbc4d50e81277e9e7 653 PRINTS PR00046 Major sigma-70 factor signature 467 475 3.4E-31 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_15715 1301bdf690fd6ebcbc4d50e81277e9e7 653 PRINTS PR00046 Major sigma-70 factor signature 612 627 3.4E-31 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_15715 1301bdf690fd6ebcbc4d50e81277e9e7 653 Pfam PF04542 Sigma-70 region 2 419 488 1.9E-21 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_15715 1301bdf690fd6ebcbc4d50e81277e9e7 653 Pfam PF04545 Sigma-70, region 4 587 640 3.5E-19 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 TSH58p_15715 1301bdf690fd6ebcbc4d50e81277e9e7 653 Gene3D G3DSA:1.10.10.10 569 653 1.2E-36 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_15715 1301bdf690fd6ebcbc4d50e81277e9e7 653 Pfam PF04546 Sigma-70, non-essential region 155 385 7.0E-53 T 14-10-2018 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_15715 1301bdf690fd6ebcbc4d50e81277e9e7 653 Gene3D G3DSA:1.10.601.10 128 488 1.2E-120 T 14-10-2018 TSH58p_15715 1301bdf690fd6ebcbc4d50e81277e9e7 653 SUPERFAMILY SSF88659 549 651 1.18E-26 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSH58p_15715 1301bdf690fd6ebcbc4d50e81277e9e7 653 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 443 456 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_27935 f4ee49542d10210ab5019f688877700b 381 Gene3D G3DSA:3.50.50.60 5 353 2.3E-117 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_27935 f4ee49542d10210ab5019f688877700b 381 Pfam PF01266 FAD dependent oxidoreductase 5 352 9.7E-52 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TSH58p_27935 f4ee49542d10210ab5019f688877700b 381 Gene3D G3DSA:3.30.9.10 84 313 2.3E-117 T 14-10-2018 TSH58p_27935 f4ee49542d10210ab5019f688877700b 381 SUPERFAMILY SSF51905 4 373 4.75E-41 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_07035 d957496325336ab3532fa2ae63b26dcc 147 SUPERFAMILY SSF55961 1 144 1.37E-32 T 14-10-2018 TSH58p_07035 d957496325336ab3532fa2ae63b26dcc 147 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 5 144 7.0E-25 T 14-10-2018 IPR010419 Carbon monoxide dehydrogenase subunit G TSH58p_07035 d957496325336ab3532fa2ae63b26dcc 147 Gene3D G3DSA:3.30.530.20 1 146 5.2E-37 T 14-10-2018 IPR023393 START-like domain superfamily TSH58p_30240 59d7ffd6a923ec44df73cfb307564ecd 1062 Gene3D G3DSA:1.20.1640.10 10 522 0.0 T 14-10-2018 TSH58p_30240 59d7ffd6a923ec44df73cfb307564ecd 1062 Gene3D G3DSA:3.30.2090.10 731 819 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_30240 59d7ffd6a923ec44df73cfb307564ecd 1062 Gene3D G3DSA:3.30.70.1440 679 876 0.0 T 14-10-2018 TSH58p_30240 59d7ffd6a923ec44df73cfb307564ecd 1062 SUPERFAMILY SSF82693 575 681 7.32E-27 T 14-10-2018 TSH58p_30240 59d7ffd6a923ec44df73cfb307564ecd 1062 Gene3D G3DSA:3.30.70.1320 135 335 0.0 T 14-10-2018 TSH58p_30240 59d7ffd6a923ec44df73cfb307564ecd 1062 SUPERFAMILY SSF82714 732 819 3.4E-19 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_30240 59d7ffd6a923ec44df73cfb307564ecd 1062 Gene3D G3DSA:3.30.70.1430 40 827 0.0 T 14-10-2018 TSH58p_30240 59d7ffd6a923ec44df73cfb307564ecd 1062 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 4 1041 0.0 T 14-10-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0006855|GO:0015562|GO:0016021 TSH58p_30240 59d7ffd6a923ec44df73cfb307564ecd 1062 Gene3D G3DSA:1.20.1640.10 523 1033 0.0 T 14-10-2018 TSH58p_30240 59d7ffd6a923ec44df73cfb307564ecd 1062 SUPERFAMILY SSF82866 299 500 1.09E-50 T 14-10-2018 TSH58p_30240 59d7ffd6a923ec44df73cfb307564ecd 1062 SUPERFAMILY SSF82714 185 273 5.49E-20 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_30240 59d7ffd6a923ec44df73cfb307564ecd 1062 Gene3D G3DSA:3.30.70.1430 577 678 0.0 T 14-10-2018 TSH58p_30240 59d7ffd6a923ec44df73cfb307564ecd 1062 SUPERFAMILY SSF82693 139 333 1.57E-27 T 14-10-2018 TSH58p_30240 59d7ffd6a923ec44df73cfb307564ecd 1062 SUPERFAMILY SSF82693 682 867 3.77E-27 T 14-10-2018 TSH58p_30240 59d7ffd6a923ec44df73cfb307564ecd 1062 SUPERFAMILY SSF82866 841 1036 2.49E-45 T 14-10-2018 TSH58p_30240 59d7ffd6a923ec44df73cfb307564ecd 1062 PRINTS PR00702 Acriflavin resistance protein family signature 447 470 5.7E-90 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_30240 59d7ffd6a923ec44df73cfb307564ecd 1062 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 5.7E-90 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_30240 59d7ffd6a923ec44df73cfb307564ecd 1062 PRINTS PR00702 Acriflavin resistance protein family signature 562 579 5.7E-90 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_30240 59d7ffd6a923ec44df73cfb307564ecd 1062 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 5.7E-90 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_30240 59d7ffd6a923ec44df73cfb307564ecd 1062 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 5.7E-90 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_30240 59d7ffd6a923ec44df73cfb307564ecd 1062 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 5.7E-90 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_30240 59d7ffd6a923ec44df73cfb307564ecd 1062 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 5.7E-90 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_30240 59d7ffd6a923ec44df73cfb307564ecd 1062 PRINTS PR00702 Acriflavin resistance protein family signature 631 645 5.7E-90 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_30240 59d7ffd6a923ec44df73cfb307564ecd 1062 PRINTS PR00702 Acriflavin resistance protein family signature 394 418 5.7E-90 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_30240 59d7ffd6a923ec44df73cfb307564ecd 1062 SUPERFAMILY SSF82693 41 134 1.94E-25 T 14-10-2018 TSH58p_30240 59d7ffd6a923ec44df73cfb307564ecd 1062 Pfam PF00873 AcrB/AcrD/AcrF family 3 1036 0.0 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_30240 59d7ffd6a923ec44df73cfb307564ecd 1062 Gene3D G3DSA:3.30.2090.10 181 278 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_09805 7051f00145c14bcab7ae002adbf57d75 229 Gene3D G3DSA:2.30.130.40 7 122 7.9E-28 T 14-10-2018 TSH58p_09805 7051f00145c14bcab7ae002adbf57d75 229 SMART SM00464 16 213 4.4E-10 T 14-10-2018 IPR003111 Lon, substrate-binding domain TSH58p_09805 7051f00145c14bcab7ae002adbf57d75 229 SUPERFAMILY SSF88697 16 211 9.44E-46 T 14-10-2018 IPR015947 PUA-like superfamily TSH58p_09805 7051f00145c14bcab7ae002adbf57d75 229 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 17 120 3.4E-15 T 14-10-2018 IPR003111 Lon, substrate-binding domain TSH58p_09805 7051f00145c14bcab7ae002adbf57d75 229 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 173 211 4.5E-6 T 14-10-2018 IPR003111 Lon, substrate-binding domain TSH58p_16915 97a5643f461200192cbe71bb6c1e6302 226 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 13 221 1.9E-54 T 14-10-2018 IPR006346 2-phosphoglycolate phosphatase-like, prokaryotic GO:0016791 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 TSH58p_16915 97a5643f461200192cbe71bb6c1e6302 226 Gene3D G3DSA:1.10.150.240 25 92 3.4E-51 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 TSH58p_16915 97a5643f461200192cbe71bb6c1e6302 226 SUPERFAMILY SSF56784 9 222 4.2E-52 T 14-10-2018 IPR036412 HAD-like superfamily TSH58p_16915 97a5643f461200192cbe71bb6c1e6302 226 Pfam PF13419 Haloacid dehalogenase-like hydrolase 13 192 4.7E-28 T 14-10-2018 TSH58p_16915 97a5643f461200192cbe71bb6c1e6302 226 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 102 187 1.8E-8 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_16915 97a5643f461200192cbe71bb6c1e6302 226 Gene3D G3DSA:3.40.50.1000 13 210 3.4E-51 T 14-10-2018 IPR023214 HAD superfamily TSH58p_16915 97a5643f461200192cbe71bb6c1e6302 226 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 139 155 4.9E-5 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_16915 97a5643f461200192cbe71bb6c1e6302 226 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 108 121 4.9E-5 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_16915 97a5643f461200192cbe71bb6c1e6302 226 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 10 21 4.9E-5 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_16915 97a5643f461200192cbe71bb6c1e6302 226 Hamap MF_00495 Phosphoglycolate phosphatase [gph]. 10 222 36.562 T 14-10-2018 IPR037512 Phosphoglycolate phosphatase, prokaryotic GO:0005975|GO:0008967 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 TSH58p_24990 39533fef0842ca594fa068b7d714f36f 210 SUPERFAMILY SSF56281 5 209 1.62E-55 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_24990 39533fef0842ca594fa068b7d714f36f 210 Pfam PF00753 Metallo-beta-lactamase superfamily 9 192 1.6E-27 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_24990 39533fef0842ca594fa068b7d714f36f 210 Gene3D G3DSA:3.60.15.10 1 210 7.5E-78 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_24990 39533fef0842ca594fa068b7d714f36f 210 SMART SM00849 12 192 1.2E-35 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_16245 484ece02c3ae433d4354ee2f5f38996d 670 Gene3D G3DSA:3.40.50.970 331 538 1.0E-78 T 14-10-2018 TSH58p_16245 484ece02c3ae433d4354ee2f5f38996d 670 Pfam PF02779 Transketolase, pyrimidine binding domain 359 529 1.3E-46 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSH58p_16245 484ece02c3ae433d4354ee2f5f38996d 670 SUPERFAMILY SSF52518 345 531 4.55E-67 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_16245 484ece02c3ae433d4354ee2f5f38996d 670 SMART SM00861 358 530 4.7E-67 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSH58p_16245 484ece02c3ae433d4354ee2f5f38996d 670 SUPERFAMILY SSF52518 14 320 7.48E-114 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_16245 484ece02c3ae433d4354ee2f5f38996d 670 Gene3D G3DSA:3.40.50.920 544 670 3.2E-39 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSH58p_16245 484ece02c3ae433d4354ee2f5f38996d 670 TIGRFAM TIGR00232 tktlase_bact: transketolase 16 668 2.8E-250 T 14-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 TSH58p_16245 484ece02c3ae433d4354ee2f5f38996d 670 Gene3D G3DSA:3.40.50.970 12 330 4.4E-117 T 14-10-2018 TSH58p_16245 484ece02c3ae433d4354ee2f5f38996d 670 SUPERFAMILY SSF52922 540 669 5.37E-40 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSH58p_16245 484ece02c3ae433d4354ee2f5f38996d 670 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 15 321 9.7E-137 T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TSH58p_16245 484ece02c3ae433d4354ee2f5f38996d 670 ProSitePatterns PS00802 Transketolase signature 2. 472 488 - T 14-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TSH58p_16245 484ece02c3ae433d4354ee2f5f38996d 670 Pfam PF02780 Transketolase, C-terminal domain 546 662 1.1E-12 T 14-10-2018 IPR033248 Transketolase, C-terminal domain TSH58p_16245 484ece02c3ae433d4354ee2f5f38996d 670 ProSitePatterns PS00801 Transketolase signature 1. 21 41 - T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TSH58p_15965 5538f72c17b3c4808f995c117a884227 350 SUPERFAMILY SSF53383 8 346 1.17E-96 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_15965 5538f72c17b3c4808f995c117a884227 350 Gene3D G3DSA:3.40.640.10 19 259 3.3E-130 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_15965 5538f72c17b3c4808f995c117a884227 350 PIRSF PIRSF038940 7 350 1.7E-153 T 14-10-2018 IPR026273 Low specificity L-threonine aldolase GO:0004793|GO:0006567 KEGG: 00260+4.1.2.48 TSH58p_15965 5538f72c17b3c4808f995c117a884227 350 Pfam PF01212 Beta-eliminating lyase 9 300 2.8E-63 T 14-10-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 TSH58p_15965 5538f72c17b3c4808f995c117a884227 350 Gene3D G3DSA:3.90.1150.10 12 338 3.3E-130 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_10120 bb8111cd985680839b8e097125166365 130 Pfam PF04379 ApaG domain 20 104 1.3E-35 T 14-10-2018 IPR007474 ApaG domain TSH58p_10120 bb8111cd985680839b8e097125166365 130 SUPERFAMILY SSF110069 5 126 6.02E-49 T 14-10-2018 IPR036767 ApaG domain superfamily TSH58p_10120 bb8111cd985680839b8e097125166365 130 Gene3D G3DSA:2.60.40.1470 2 129 9.0E-49 T 14-10-2018 IPR036767 ApaG domain superfamily TSH58p_10120 bb8111cd985680839b8e097125166365 130 Hamap MF_00791 Protein ApaG [apaG]. 2 130 32.169 T 14-10-2018 IPR023065 Uncharacterised protein family ApaG TSH58p_00230 be1c413f46d25840ff188438bc7117b3 304 Gene3D G3DSA:3.40.190.290 103 303 7.9E-16 T 14-10-2018 TSH58p_00230 be1c413f46d25840ff188438bc7117b3 304 SUPERFAMILY SSF53850 101 301 1.81E-25 T 14-10-2018 TSH58p_00230 be1c413f46d25840ff188438bc7117b3 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 16 75 6.1E-14 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_00230 be1c413f46d25840ff188438bc7117b3 304 Gene3D G3DSA:1.10.10.10 15 100 5.2E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_00230 be1c413f46d25840ff188438bc7117b3 304 Pfam PF03466 LysR substrate binding domain 100 302 4.4E-26 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_00230 be1c413f46d25840ff188438bc7117b3 304 SUPERFAMILY SSF46785 15 99 1.18E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_21925 06eef8b25f243e61e8e451c2ba608c23 155 Pfam PF01592 NifU-like N terminal domain 9 90 1.6E-20 T 14-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 TSH58p_21925 06eef8b25f243e61e8e451c2ba608c23 155 SUPERFAMILY SSF82649 1 148 3.4E-47 T 14-10-2018 TSH58p_21925 06eef8b25f243e61e8e451c2ba608c23 155 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 5 146 2.5E-46 T 14-10-2018 TSH58p_21925 06eef8b25f243e61e8e451c2ba608c23 155 Gene3D G3DSA:3.90.1010.10 1 153 5.5E-54 T 14-10-2018 TSH58p_05850 32862d93db421c2746cde32bfb3b9703 482 Pfam PF00361 Proton-conducting membrane transporter 124 418 9.6E-86 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05850 32862d93db421c2746cde32bfb3b9703 482 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 6 469 18.714 T 14-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 TSH58p_05850 32862d93db421c2746cde32bfb3b9703 482 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 10 468 1.0E-152 T 14-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 TSH58p_26585 18b0fcd9da75927bb53b119b0f94898c 439 SUPERFAMILY SSF117892 89 240 3.4E-8 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily TSH58p_26585 18b0fcd9da75927bb53b119b0f94898c 439 Pfam PF01145 SPFH domain / Band 7 family 58 250 9.3E-17 T 14-10-2018 IPR001107 Band 7 domain TSH58p_26585 18b0fcd9da75927bb53b119b0f94898c 439 SMART SM00244 53 235 4.9E-4 T 14-10-2018 IPR001107 Band 7 domain TSH58p_06665 ceec47afcf8c3fb382b9fd221bfac927 82 Pfam PF10073 Uncharacterized protein conserved in bacteria (DUF2312) 8 79 1.2E-36 T 14-10-2018 IPR018753 Azospirillum phage Cd, Gp10 TSH58p_06665 ceec47afcf8c3fb382b9fd221bfac927 82 Hamap MF_00797 UPF0335 protein . 3 80 23.288 T 14-10-2018 IPR018753 Azospirillum phage Cd, Gp10 TSH58p_21410 aae0eb62066194c32c99103dd188a43d 270 SUPERFAMILY SSF46785 36 131 1.46E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_21410 aae0eb62066194c32c99103dd188a43d 270 Pfam PF07729 FCD domain 115 234 1.5E-29 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_21410 aae0eb62066194c32c99103dd188a43d 270 SMART SM00895 112 236 9.5E-22 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_21410 aae0eb62066194c32c99103dd188a43d 270 SUPERFAMILY SSF48008 111 240 5.23E-30 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_21410 aae0eb62066194c32c99103dd188a43d 270 SMART SM00345 44 102 6.9E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_21410 aae0eb62066194c32c99103dd188a43d 270 Gene3D G3DSA:1.10.10.10 36 103 6.0E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_21410 aae0eb62066194c32c99103dd188a43d 270 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 76 92 4.5E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_21410 aae0eb62066194c32c99103dd188a43d 270 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 62 76 4.5E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_21410 aae0eb62066194c32c99103dd188a43d 270 Pfam PF00392 Bacterial regulatory proteins, gntR family 42 102 3.0E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_21410 aae0eb62066194c32c99103dd188a43d 270 Gene3D G3DSA:1.20.120.530 110 245 2.7E-31 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_18530 aae0eb62066194c32c99103dd188a43d 270 SUPERFAMILY SSF46785 36 131 1.46E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_18530 aae0eb62066194c32c99103dd188a43d 270 Pfam PF07729 FCD domain 115 234 1.5E-29 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_18530 aae0eb62066194c32c99103dd188a43d 270 SMART SM00895 112 236 9.5E-22 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_18530 aae0eb62066194c32c99103dd188a43d 270 SUPERFAMILY SSF48008 111 240 5.23E-30 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_18530 aae0eb62066194c32c99103dd188a43d 270 SMART SM00345 44 102 6.9E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_18530 aae0eb62066194c32c99103dd188a43d 270 Gene3D G3DSA:1.10.10.10 36 103 6.0E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_18530 aae0eb62066194c32c99103dd188a43d 270 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 76 92 4.5E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_18530 aae0eb62066194c32c99103dd188a43d 270 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 62 76 4.5E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_18530 aae0eb62066194c32c99103dd188a43d 270 Pfam PF00392 Bacterial regulatory proteins, gntR family 42 102 3.0E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_18530 aae0eb62066194c32c99103dd188a43d 270 Gene3D G3DSA:1.20.120.530 110 245 2.7E-31 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_30765 9370c542fa297cc05d26c3790ff6e2d9 343 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 221 310 1.7E-23 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_30765 9370c542fa297cc05d26c3790ff6e2d9 343 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 223 290 3.2E-15 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_30765 9370c542fa297cc05d26c3790ff6e2d9 343 SMART SM00382 30 221 9.4E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_30765 9370c542fa297cc05d26c3790ff6e2d9 343 Pfam PF00005 ABC transporter 22 171 9.0E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_30765 9370c542fa297cc05d26c3790ff6e2d9 343 Gene3D G3DSA:3.40.50.300 1 324 2.1E-99 T 14-10-2018 TSH58p_30765 9370c542fa297cc05d26c3790ff6e2d9 343 SUPERFAMILY SSF52540 1 243 1.36E-72 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_30765 9370c542fa297cc05d26c3790ff6e2d9 343 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_27590 449d4009ea031f4e29a2caa03ad49cad 109 SUPERFAMILY SSF101801 32 107 1.15E-22 T 14-10-2018 IPR036429 SpoA-like superfamily TSH58p_27590 449d4009ea031f4e29a2caa03ad49cad 109 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 34 104 9.6E-25 T 14-10-2018 IPR001543 Surface presentation of antigen (SpoA) TSH58p_27590 449d4009ea031f4e29a2caa03ad49cad 109 PRINTS PR00956 Flagellar motor switch protein FliN signature 51 67 9.4E-25 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 TSH58p_27590 449d4009ea031f4e29a2caa03ad49cad 109 PRINTS PR00956 Flagellar motor switch protein FliN signature 34 50 9.4E-25 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 TSH58p_27590 449d4009ea031f4e29a2caa03ad49cad 109 PRINTS PR00956 Flagellar motor switch protein FliN signature 80 95 9.4E-25 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 TSH58p_27590 449d4009ea031f4e29a2caa03ad49cad 109 PRINTS PR00956 Flagellar motor switch protein FliN signature 67 80 9.4E-25 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 TSH58p_27590 449d4009ea031f4e29a2caa03ad49cad 109 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 32 106 1.6E-31 T 14-10-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 TSH58p_27590 449d4009ea031f4e29a2caa03ad49cad 109 Gene3D G3DSA:2.30.330.10 22 108 1.2E-30 T 14-10-2018 IPR036429 SpoA-like superfamily TSH58p_22205 6de1a528252a584d5db36f2d2f79d53d 272 Gene3D G3DSA:1.20.1260.10 49 224 6.4E-25 T 14-10-2018 IPR012347 Ferritin-like TSH58p_22205 6de1a528252a584d5db36f2d2f79d53d 272 Pfam PF03713 Domain of unknown function (DUF305) 59 219 1.0E-23 T 14-10-2018 IPR005183 Domain of unknown function DUF305 TSH58p_16035 2a2bd87eec87ffd2662fd5c7f66ebf01 309 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 21 294 1.3E-102 T 14-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 TSH58p_16035 2a2bd87eec87ffd2662fd5c7f66ebf01 309 Pfam PF01040 UbiA prenyltransferase family 35 279 3.5E-59 T 14-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 TSH58p_16035 2a2bd87eec87ffd2662fd5c7f66ebf01 309 Gene3D G3DSA:1.10.357.140 29 180 3.6E-17 T 14-10-2018 TSH58p_16035 2a2bd87eec87ffd2662fd5c7f66ebf01 309 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 72 94 - T 14-10-2018 IPR030470 UbiA prenyltransferase conserved site TSH58p_16035 2a2bd87eec87ffd2662fd5c7f66ebf01 309 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 18 298 20.201 T 14-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 TSH58p_26500 ccb94f75b696fc1fa63ed22e4936523f 625 SUPERFAMILY SSF49879 526 610 1.66E-15 T 14-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 TSH58p_26500 ccb94f75b696fc1fa63ed22e4936523f 625 Gene3D G3DSA:2.60.200.20 517 613 5.2E-15 T 14-10-2018 TSH58p_26500 ccb94f75b696fc1fa63ed22e4936523f 625 SMART SM00240 535 584 2.0E-5 T 14-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TSH58p_26500 ccb94f75b696fc1fa63ed22e4936523f 625 Pfam PF00498 FHA domain 537 607 5.6E-10 T 14-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TSH58p_04525 9d8fda546015a9e26d87ae11ee0e3e60 372 Gene3D G3DSA:3.40.50.300 24 207 4.0E-44 T 14-10-2018 TSH58p_04525 9d8fda546015a9e26d87ae11ee0e3e60 372 SUPERFAMILY SSF52540 23 246 3.67E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_04525 9d8fda546015a9e26d87ae11ee0e3e60 372 Pfam PF13177 DNA polymerase III, delta subunit 27 207 1.0E-31 T 14-10-2018 TSH58p_11560 6d134cef1d2b6d258351f78c821fc8bd 353 SUPERFAMILY SSF50331 237 348 1.19E-13 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSH58p_11560 6d134cef1d2b6d258351f78c821fc8bd 353 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_11560 6d134cef1d2b6d258351f78c821fc8bd 353 Pfam PF08402 TOBE domain 279 348 3.0E-8 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TSH58p_11560 6d134cef1d2b6d258351f78c821fc8bd 353 Pfam PF00005 ABC transporter 21 162 2.6E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_11560 6d134cef1d2b6d258351f78c821fc8bd 353 SMART SM00382 29 212 5.9E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_11560 6d134cef1d2b6d258351f78c821fc8bd 353 Gene3D G3DSA:2.40.50.940 224 344 3.0E-7 T 14-10-2018 TSH58p_11560 6d134cef1d2b6d258351f78c821fc8bd 353 Gene3D G3DSA:3.40.50.300 5 223 1.1E-63 T 14-10-2018 TSH58p_11560 6d134cef1d2b6d258351f78c821fc8bd 353 SUPERFAMILY SSF52540 5 242 2.66E-80 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_11560 6d134cef1d2b6d258351f78c821fc8bd 353 Gene3D G3DSA:2.40.50.140 285 340 3.0E-7 T 14-10-2018 TSH58p_05020 9149e705dd64e82b4d836887b7d35c00 786 Gene3D G3DSA:3.30.365.10 9 784 4.7E-280 T 14-10-2018 TSH58p_05020 9149e705dd64e82b4d836887b7d35c00 786 SUPERFAMILY SSF54665 20 143 7.46E-40 T 14-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily TSH58p_05020 9149e705dd64e82b4d836887b7d35c00 786 SUPERFAMILY SSF56003 142 777 8.24E-200 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 TSH58p_05020 9149e705dd64e82b4d836887b7d35c00 786 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 36 142 1.0E-25 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead TSH58p_05020 9149e705dd64e82b4d836887b7d35c00 786 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 163 706 5.3E-198 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 TSH58p_05020 9149e705dd64e82b4d836887b7d35c00 786 TIGRFAM TIGR02965 xanthine_xdhB: xanthine dehydrogenase, molybdopterin binding subunit 21 778 0.0 T 14-10-2018 IPR014309 Xanthine dehydrogenase, molybdopterin binding subunit GO:0030151 KEGG: 00230+1.17.1.4+1.17.3.2|KEGG: 00232+1.17.3.2|KEGG: 00983+1.17.3.2|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999 TSH58p_05020 9149e705dd64e82b4d836887b7d35c00 786 SMART SM01008 35 142 1.0E-43 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead TSH58p_02225 88d77cc3df7f15ac391d68c8652ee34d 209 Gene3D G3DSA:3.40.50.850 1 206 6.0E-58 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TSH58p_02225 88d77cc3df7f15ac391d68c8652ee34d 209 Pfam PF00857 Isochorismatase family 22 194 1.6E-33 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 TSH58p_02225 88d77cc3df7f15ac391d68c8652ee34d 209 SUPERFAMILY SSF52499 7 203 2.62E-48 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TSH58p_10300 38676a61fc2c4b07f6bd259f72c3816a 332 Pfam PF00034 Cytochrome c 197 306 1.8E-9 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_10300 38676a61fc2c4b07f6bd259f72c3816a 332 Gene3D G3DSA:1.10.760.10 39 312 3.3E-117 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_10300 38676a61fc2c4b07f6bd259f72c3816a 332 Pfam PF03150 Di-haem cytochrome c peroxidase 42 188 6.1E-54 T 14-10-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 TSH58p_10300 38676a61fc2c4b07f6bd259f72c3816a 332 Gene3D G3DSA:1.10.760.10 41 188 3.3E-117 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_10300 38676a61fc2c4b07f6bd259f72c3816a 332 SUPERFAMILY SSF46626 22 176 7.85E-50 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_10300 38676a61fc2c4b07f6bd259f72c3816a 332 SUPERFAMILY SSF46626 175 326 3.78E-43 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_10300 38676a61fc2c4b07f6bd259f72c3816a 332 PIRSF PIRSF000294 3 330 9.7E-131 T 14-10-2018 IPR026259 Di-c-type haem protein, MauG/cytochrome c peroxidase GO:0016491|GO:0020037|GO:0055114 TSH58p_29740 b16446046eb9ccd2dd6e5c52ebca101f 286 SUPERFAMILY SSF53448 9 214 1.78E-28 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_29740 b16446046eb9ccd2dd6e5c52ebca101f 286 Gene3D G3DSA:3.90.550.10 5 230 6.6E-25 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_29740 b16446046eb9ccd2dd6e5c52ebca101f 286 Pfam PF00535 Glycosyl transferase family 2 10 131 1.2E-17 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_31500 818aa9940118d64c76e882a50ea0c284 304 SUPERFAMILY SSF46785 5 90 8.47E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_31500 818aa9940118d64c76e882a50ea0c284 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 4.2E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_31500 818aa9940118d64c76e882a50ea0c284 304 Pfam PF03466 LysR substrate binding domain 90 296 6.3E-40 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_31500 818aa9940118d64c76e882a50ea0c284 304 SUPERFAMILY SSF53850 92 300 3.72E-43 T 14-10-2018 TSH58p_31500 818aa9940118d64c76e882a50ea0c284 304 Gene3D G3DSA:1.10.10.10 5 90 1.8E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_31500 818aa9940118d64c76e882a50ea0c284 304 Gene3D G3DSA:3.40.190.10 166 267 1.7E-53 T 14-10-2018 TSH58p_31500 818aa9940118d64c76e882a50ea0c284 304 Gene3D G3DSA:3.40.190.10 94 292 1.7E-53 T 14-10-2018 TSH58p_09615 9fabe08aa431f238166ceea776790895 208 Gene3D G3DSA:3.30.1330.200 25 182 3.5E-47 T 14-10-2018 IPR038592 CheD-like superfamily TSH58p_09615 9fabe08aa431f238166ceea776790895 208 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 24 177 28.142 T 14-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 TSH58p_09615 9fabe08aa431f238166ceea776790895 208 Pfam PF03975 CheD chemotactic sensory transduction 71 172 1.1E-28 T 14-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 TSH58p_09615 9fabe08aa431f238166ceea776790895 208 SUPERFAMILY SSF64438 28 176 3.94E-46 T 14-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic TSH58p_19845 8703ed555880d83ae6fa616fd5963ebd 552 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 383 529 7.5E-44 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TSH58p_19845 8703ed555880d83ae6fa616fd5963ebd 552 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 419 438 - T 14-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 TSH58p_19845 8703ed555880d83ae6fa616fd5963ebd 552 Gene3D G3DSA:3.40.50.970 358 550 2.4E-58 T 14-10-2018 TSH58p_19845 8703ed555880d83ae6fa616fd5963ebd 552 SUPERFAMILY SSF52518 361 538 1.02E-59 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_19845 8703ed555880d83ae6fa616fd5963ebd 552 SUPERFAMILY SSF52518 1 177 4.98E-54 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_19845 8703ed555880d83ae6fa616fd5963ebd 552 SUPERFAMILY SSF52467 153 353 9.16E-38 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TSH58p_19845 8703ed555880d83ae6fa616fd5963ebd 552 Gene3D G3DSA:3.40.50.1220 181 352 2.5E-36 T 14-10-2018 TSH58p_19845 8703ed555880d83ae6fa616fd5963ebd 552 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 188 324 9.2E-28 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 TSH58p_19845 8703ed555880d83ae6fa616fd5963ebd 552 Gene3D G3DSA:3.40.50.970 1 180 4.3E-63 T 14-10-2018 TSH58p_19845 8703ed555880d83ae6fa616fd5963ebd 552 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 168 2.0E-55 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 TSH58p_12805 c712dbe2b191227af9589d770e0fdd90 282 Gene3D G3DSA:2.60.120.10 20 278 1.6E-97 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_12805 c712dbe2b191227af9589d770e0fdd90 282 Pfam PF02678 Pirin 24 124 2.9E-37 T 14-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 TSH58p_12805 c712dbe2b191227af9589d770e0fdd90 282 SUPERFAMILY SSF51182 7 282 7.9E-86 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_12805 c712dbe2b191227af9589d770e0fdd90 282 PIRSF PIRSF006232 5 282 1.9E-96 T 14-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 TSH58p_12805 c712dbe2b191227af9589d770e0fdd90 282 Gene3D G3DSA:2.60.120.10 146 252 1.6E-97 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_12805 c712dbe2b191227af9589d770e0fdd90 282 Pfam PF05726 Pirin C-terminal cupin domain 180 282 8.8E-30 T 14-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 TSH58p_16645 498c272502bd24aa1789a6ac22fe1a85 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_16645 498c272502bd24aa1789a6ac22fe1a85 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 8.5E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_16645 498c272502bd24aa1789a6ac22fe1a85 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 8.5E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_16645 498c272502bd24aa1789a6ac22fe1a85 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 8.5E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_16645 498c272502bd24aa1789a6ac22fe1a85 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 8.5E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_16645 498c272502bd24aa1789a6ac22fe1a85 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 8.5E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_16645 498c272502bd24aa1789a6ac22fe1a85 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 8.5E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_16645 498c272502bd24aa1789a6ac22fe1a85 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 247 5.1E-63 T 14-10-2018 TSH58p_16645 498c272502bd24aa1789a6ac22fe1a85 253 Gene3D G3DSA:3.40.50.720 2 251 2.1E-84 T 14-10-2018 TSH58p_16645 498c272502bd24aa1789a6ac22fe1a85 253 SUPERFAMILY SSF51735 1 250 7.72E-83 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_16645 498c272502bd24aa1789a6ac22fe1a85 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 8.2E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_16645 498c272502bd24aa1789a6ac22fe1a85 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 8.2E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_16645 498c272502bd24aa1789a6ac22fe1a85 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 8.2E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03015 c0a04127525e33d2f34a83b910e98463 443 Pfam PF01979 Amidohydrolase family 59 413 9.7E-53 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TSH58p_03015 c0a04127525e33d2f34a83b910e98463 443 SUPERFAMILY SSF51556 62 366 7.29E-68 T 14-10-2018 IPR032466 Metal-dependent hydrolase TSH58p_03015 c0a04127525e33d2f34a83b910e98463 443 Gene3D G3DSA:2.30.40.10 19 429 6.2E-108 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_03015 c0a04127525e33d2f34a83b910e98463 443 SUPERFAMILY SSF51338 6 440 9.11E-27 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_03015 c0a04127525e33d2f34a83b910e98463 443 Gene3D G3DSA:3.20.20.140 63 358 6.2E-108 T 14-10-2018 TSH58p_11980 6789bd25e1eb87d2a7a02bfb24af20fc 284 SUPERFAMILY SSF46689 64 116 7.17E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_11980 6789bd25e1eb87d2a7a02bfb24af20fc 284 Gene3D G3DSA:1.10.10.60 65 119 3.2E-11 T 14-10-2018 TSH58p_11980 6789bd25e1eb87d2a7a02bfb24af20fc 284 Gene3D G3DSA:1.10.10.60 9 64 6.9E-12 T 14-10-2018 TSH58p_11980 6789bd25e1eb87d2a7a02bfb24af20fc 284 SUPERFAMILY SSF46689 12 59 2.78E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_11980 6789bd25e1eb87d2a7a02bfb24af20fc 284 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 65 108 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 TSH58p_11980 6789bd25e1eb87d2a7a02bfb24af20fc 284 SUPERFAMILY SSF55136 133 283 1.06E-36 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily TSH58p_11980 6789bd25e1eb87d2a7a02bfb24af20fc 284 Gene3D G3DSA:3.20.80.10 132 284 7.1E-43 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily TSH58p_11980 6789bd25e1eb87d2a7a02bfb24af20fc 284 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 96 112 3.6E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TSH58p_11980 6789bd25e1eb87d2a7a02bfb24af20fc 284 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 81 96 3.6E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TSH58p_11980 6789bd25e1eb87d2a7a02bfb24af20fc 284 SMART SM00342 28 112 1.5E-23 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TSH58p_11980 6789bd25e1eb87d2a7a02bfb24af20fc 284 Pfam PF12833 Helix-turn-helix domain 34 114 5.8E-19 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TSH58p_11980 6789bd25e1eb87d2a7a02bfb24af20fc 284 Pfam PF06445 GyrI-like small molecule binding domain 132 283 3.5E-37 T 14-10-2018 IPR029442 GyrI-like small molecule binding domain TSH58p_11980 6789bd25e1eb87d2a7a02bfb24af20fc 284 SMART SM00871 132 284 4.6E-38 T 14-10-2018 IPR010499 Bacterial transcription activator, effector binding TSH58p_11325 54a6225f8e2a2f15bb5b1a2f27752002 138 Pfam PF05443 ROS/MUCR transcriptional regulator protein 10 130 2.2E-51 T 14-10-2018 IPR008807 ROSMUCR transcriptional regulator GO:0003677|GO:0006355|GO:0008270 TSH58p_11325 54a6225f8e2a2f15bb5b1a2f27752002 138 Gene3D G3DSA:1.10.10.1550 57 113 2.3E-31 T 14-10-2018 TSH58p_01595 10f9df49ac31c62e81d747a8ae4683f3 328 PIRSF PIRSF018266 1 326 6.0E-79 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component TSH58p_01595 10f9df49ac31c62e81d747a8ae4683f3 328 Pfam PF16220 Domain of unknown function (DUF4880) 12 53 7.8E-11 T 14-10-2018 IPR032623 FecR, N-terminal TSH58p_01595 10f9df49ac31c62e81d747a8ae4683f3 328 Gene3D G3DSA:2.60.120.1440 106 245 1.5E-25 T 14-10-2018 TSH58p_01595 10f9df49ac31c62e81d747a8ae4683f3 328 Pfam PF04773 FecR protein 121 210 1.3E-21 T 14-10-2018 IPR006860 FecR protein TSH58p_06315 f8a4d816b385fe4e4b3779dfceec12f1 337 SUPERFAMILY SSF51735 117 285 1.48E-36 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_06315 f8a4d816b385fe4e4b3779dfceec12f1 337 TIGRFAM TIGR02817 adh_fam_1: zinc-binding alcohol dehydrogenase family protein 2 337 1.3E-166 T 14-10-2018 IPR014182 Alcohol dehydrogenase, zinc-binding type 1 GO:0008270 TSH58p_06315 f8a4d816b385fe4e4b3779dfceec12f1 337 Pfam PF13602 Zinc-binding dehydrogenase 194 334 9.0E-22 T 14-10-2018 TSH58p_06315 f8a4d816b385fe4e4b3779dfceec12f1 337 SUPERFAMILY SSF50129 10 147 2.74E-33 T 14-10-2018 IPR011032 GroES-like superfamily TSH58p_06315 f8a4d816b385fe4e4b3779dfceec12f1 337 SMART SM00829 13 334 3.5E-11 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TSH58p_06315 f8a4d816b385fe4e4b3779dfceec12f1 337 Gene3D G3DSA:3.90.180.10 22 334 1.9E-111 T 14-10-2018 TSH58p_06315 f8a4d816b385fe4e4b3779dfceec12f1 337 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 93 2.8E-5 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TSH58p_06315 f8a4d816b385fe4e4b3779dfceec12f1 337 Gene3D G3DSA:3.40.50.720 128 273 1.9E-111 T 14-10-2018 TSH58p_26745 813bc7b6de94c1b6235d84433138142e 390 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 5.4E-11 T 14-10-2018 IPR027399 Alcohol dehydrogenase GroES-associated TSH58p_26745 813bc7b6de94c1b6235d84433138142e 390 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 TSH58p_26745 813bc7b6de94c1b6235d84433138142e 390 Gene3D G3DSA:3.90.180.10 9 376 1.6E-131 T 14-10-2018 TSH58p_26745 813bc7b6de94c1b6235d84433138142e 390 SUPERFAMILY SSF50129 1 199 2.59E-60 T 14-10-2018 IPR011032 GroES-like superfamily TSH58p_26745 813bc7b6de94c1b6235d84433138142e 390 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 150 3.5E-29 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TSH58p_26745 813bc7b6de94c1b6235d84433138142e 390 Pfam PF00107 Zinc-binding dehydrogenase 197 272 1.1E-11 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TSH58p_26745 813bc7b6de94c1b6235d84433138142e 390 SUPERFAMILY SSF51735 164 352 8.98E-65 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_26745 813bc7b6de94c1b6235d84433138142e 390 Gene3D G3DSA:3.40.50.720 178 341 1.6E-131 T 14-10-2018 TSH58p_21280 84863d57d5d9dd846599dcb8bb6eed89 220 SUPERFAMILY SSF64438 41 187 4.58E-43 T 14-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic TSH58p_21280 84863d57d5d9dd846599dcb8bb6eed89 220 Gene3D G3DSA:3.30.1330.200 40 195 3.5E-43 T 14-10-2018 IPR038592 CheD-like superfamily TSH58p_21280 84863d57d5d9dd846599dcb8bb6eed89 220 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 37 189 27.02 T 14-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 TSH58p_21280 84863d57d5d9dd846599dcb8bb6eed89 220 Pfam PF03975 CheD chemotactic sensory transduction 84 182 2.1E-25 T 14-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 TSH58p_30690 0b88252224027f5aba922fa9bf3a8174 78 SUPERFAMILY SSF47413 2 68 4.02E-17 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_30690 0b88252224027f5aba922fa9bf3a8174 78 SMART SM00530 7 62 4.1E-13 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_30690 0b88252224027f5aba922fa9bf3a8174 78 Gene3D G3DSA:1.10.260.40 2 65 1.5E-17 T 14-10-2018 TSH58p_30690 0b88252224027f5aba922fa9bf3a8174 78 Pfam PF01381 Helix-turn-helix 8 62 2.4E-13 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_00495 712a6c17f7b3623a94c4bc813d2b5d42 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 195 0.0065 T 14-10-2018 TSH58p_00495 712a6c17f7b3623a94c4bc813d2b5d42 253 Gene3D G3DSA:3.40.50.720 1 252 1.7E-74 T 14-10-2018 TSH58p_00495 712a6c17f7b3623a94c4bc813d2b5d42 253 SUPERFAMILY SSF51735 1 250 4.6E-62 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_00495 712a6c17f7b3623a94c4bc813d2b5d42 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 5.4E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00495 712a6c17f7b3623a94c4bc813d2b5d42 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 5.4E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00495 712a6c17f7b3623a94c4bc813d2b5d42 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 5.4E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00495 712a6c17f7b3623a94c4bc813d2b5d42 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 5.4E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00495 712a6c17f7b3623a94c4bc813d2b5d42 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.4E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00495 712a6c17f7b3623a94c4bc813d2b5d42 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 5.4E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00495 712a6c17f7b3623a94c4bc813d2b5d42 253 Pfam PF00106 short chain dehydrogenase 7 199 9.2E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00495 712a6c17f7b3623a94c4bc813d2b5d42 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 1.8E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00495 712a6c17f7b3623a94c4bc813d2b5d42 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 1.8E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00495 712a6c17f7b3623a94c4bc813d2b5d42 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 1.8E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_00495 712a6c17f7b3623a94c4bc813d2b5d42 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_28205 09e835c6733b6beabef6ee8cbcfde715 717 SMART SM00388 340 405 6.0E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_28205 09e835c6733b6beabef6ee8cbcfde715 717 Pfam PF00072 Response regulator receiver domain 594 705 8.3E-13 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_28205 09e835c6733b6beabef6ee8cbcfde715 717 Pfam PF00512 His Kinase A (phospho-acceptor) domain 341 405 3.7E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_28205 09e835c6733b6beabef6ee8cbcfde715 717 SUPERFAMILY SSF55874 394 562 3.14E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_28205 09e835c6733b6beabef6ee8cbcfde715 717 PRINTS PR00344 Bacterial sensor protein C-terminal signature 485 499 5.3E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_28205 09e835c6733b6beabef6ee8cbcfde715 717 PRINTS PR00344 Bacterial sensor protein C-terminal signature 503 513 5.3E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_28205 09e835c6733b6beabef6ee8cbcfde715 717 PRINTS PR00344 Bacterial sensor protein C-terminal signature 520 538 5.3E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_28205 09e835c6733b6beabef6ee8cbcfde715 717 PRINTS PR00344 Bacterial sensor protein C-terminal signature 544 557 5.3E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_28205 09e835c6733b6beabef6ee8cbcfde715 717 SUPERFAMILY SSF52172 590 710 9.82E-24 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_28205 09e835c6733b6beabef6ee8cbcfde715 717 SMART SM00448 592 706 1.9E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_28205 09e835c6733b6beabef6ee8cbcfde715 717 SUPERFAMILY SSF47384 327 405 3.53E-12 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_28205 09e835c6733b6beabef6ee8cbcfde715 717 Gene3D G3DSA:1.10.287.130 304 403 8.2E-16 T 14-10-2018 TSH58p_28205 09e835c6733b6beabef6ee8cbcfde715 717 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 450 558 1.4E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_28205 09e835c6733b6beabef6ee8cbcfde715 717 Gene3D G3DSA:3.30.565.10 412 561 3.1E-33 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_28205 09e835c6733b6beabef6ee8cbcfde715 717 SMART SM00387 449 560 1.8E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_28205 09e835c6733b6beabef6ee8cbcfde715 717 Gene3D G3DSA:3.30.450.20 26 180 1.1E-26 T 14-10-2018 TSH58p_28205 09e835c6733b6beabef6ee8cbcfde715 717 Gene3D G3DSA:3.40.50.2300 584 716 3.9E-20 T 14-10-2018 TSH58p_03205 933045661ad7bdbb15784fe080f80621 441 Pfam PF01266 FAD dependent oxidoreductase 44 396 2.5E-44 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TSH58p_03205 933045661ad7bdbb15784fe080f80621 441 Gene3D G3DSA:3.50.50.60 44 395 2.5E-65 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_03205 933045661ad7bdbb15784fe080f80621 441 Gene3D G3DSA:3.30.9.10 138 359 2.5E-65 T 14-10-2018 TSH58p_03205 933045661ad7bdbb15784fe080f80621 441 SUPERFAMILY SSF51905 43 428 7.77E-46 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_22220 f47a9d18366d208c38e4b0c7f5c385f1 168 Gene3D G3DSA:3.30.530.20 4 164 4.7E-12 T 14-10-2018 IPR023393 START-like domain superfamily TSH58p_22220 f47a9d18366d208c38e4b0c7f5c385f1 168 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 8 135 8.8E-10 T 14-10-2018 IPR019587 Polyketide cyclase/dehydrase TSH58p_22220 f47a9d18366d208c38e4b0c7f5c385f1 168 SUPERFAMILY SSF55961 6 146 1.41E-13 T 14-10-2018 TSH58p_09850 b1a8f4155e6ecf1e1bd68c65eebba065 555 SUPERFAMILY SSF52172 20 158 1.61E-8 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_09850 b1a8f4155e6ecf1e1bd68c65eebba065 555 Gene3D G3DSA:1.10.3210.10 317 523 7.7E-64 T 14-10-2018 TSH58p_09850 b1a8f4155e6ecf1e1bd68c65eebba065 555 Gene3D G3DSA:3.30.450.40 170 316 5.1E-6 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_09850 b1a8f4155e6ecf1e1bd68c65eebba065 555 Gene3D G3DSA:3.40.50.2300 13 167 3.7E-8 T 14-10-2018 TSH58p_09850 b1a8f4155e6ecf1e1bd68c65eebba065 555 Pfam PF13487 HD domain 396 465 4.4E-14 T 14-10-2018 TSH58p_09850 b1a8f4155e6ecf1e1bd68c65eebba065 555 Pfam PF11849 Domain of unknown function (DUF3369) 150 315 1.3E-29 T 14-10-2018 IPR021800 Domain of unknown function DUF3369 TSH58p_09850 b1a8f4155e6ecf1e1bd68c65eebba065 555 SUPERFAMILY SSF109604 328 512 8.11E-30 T 14-10-2018 TSH58p_09850 b1a8f4155e6ecf1e1bd68c65eebba065 555 SMART SM00471 333 483 1.2E-5 T 14-10-2018 IPR003607 HD/PDEase domain TSH58p_09850 b1a8f4155e6ecf1e1bd68c65eebba065 555 SUPERFAMILY SSF55781 236 318 1.5E-5 T 14-10-2018 TSH58p_00240 247f767a227b3a0da11baccc102ed399 499 Gene3D G3DSA:3.40.605.10 24 459 8.6E-158 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TSH58p_00240 247f767a227b3a0da11baccc102ed399 499 Gene3D G3DSA:3.40.309.10 249 451 8.6E-158 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TSH58p_00240 247f767a227b3a0da11baccc102ed399 499 SUPERFAMILY SSF53720 2 482 3.67E-148 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSH58p_00240 247f767a227b3a0da11baccc102ed399 499 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 4 482 3.9E-202 T 14-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 TSH58p_00240 247f767a227b3a0da11baccc102ed399 499 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 274 285 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 TSH58p_00240 247f767a227b3a0da11baccc102ed399 499 Pfam PF00171 Aldehyde dehydrogenase family 18 478 2.7E-139 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TSH58p_13340 110217bed6966b2e9909e47428446138 302 SUPERFAMILY SSF161098 80 280 2.35E-22 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_13340 110217bed6966b2e9909e47428446138 302 Gene3D G3DSA:1.10.3720.10 75 295 4.6E-20 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_13340 110217bed6966b2e9909e47428446138 302 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 10 41 5.6E-6 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TSH58p_13340 110217bed6966b2e9909e47428446138 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 298 1.9E-29 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_15005 8d83da39e60a635f631e9997657eae8f 248 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 223 245 4.1E-11 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSH58p_15005 8d83da39e60a635f631e9997657eae8f 248 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_15005 8d83da39e60a635f631e9997657eae8f 248 SUPERFAMILY SSF52540 5 244 3.79E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_15005 8d83da39e60a635f631e9997657eae8f 248 SMART SM00382 29 223 4.8E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_15005 8d83da39e60a635f631e9997657eae8f 248 Gene3D G3DSA:3.40.50.300 4 245 1.5E-59 T 14-10-2018 TSH58p_15005 8d83da39e60a635f631e9997657eae8f 248 Pfam PF00005 ABC transporter 21 174 1.0E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_00535 60e34f5b776a5dc0cef6a7f7a1373289 590 Pfam PF13432 Tetratricopeptide repeat 6 36 0.0015 T 14-10-2018 TSH58p_00535 60e34f5b776a5dc0cef6a7f7a1373289 590 Pfam PF13432 Tetratricopeptide repeat 154 207 0.016 T 14-10-2018 TSH58p_00535 60e34f5b776a5dc0cef6a7f7a1373289 590 Pfam PF13414 TPR repeat 80 118 1.3E-6 T 14-10-2018 TSH58p_00535 60e34f5b776a5dc0cef6a7f7a1373289 590 SUPERFAMILY SSF102114 284 569 9.81E-46 T 14-10-2018 TSH58p_00535 60e34f5b776a5dc0cef6a7f7a1373289 590 SUPERFAMILY SSF48452 10 231 2.91E-31 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_00535 60e34f5b776a5dc0cef6a7f7a1373289 590 Pfam PF04055 Radical SAM superfamily 292 429 3.9E-18 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSH58p_00535 60e34f5b776a5dc0cef6a7f7a1373289 590 SMART SM00028 106 139 32.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_00535 60e34f5b776a5dc0cef6a7f7a1373289 590 SMART SM00028 4 37 0.58 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_00535 60e34f5b776a5dc0cef6a7f7a1373289 590 SMART SM00028 140 173 95.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_00535 60e34f5b776a5dc0cef6a7f7a1373289 590 SMART SM00028 72 105 0.083 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_00535 60e34f5b776a5dc0cef6a7f7a1373289 590 SMART SM00028 174 207 3.8 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_00535 60e34f5b776a5dc0cef6a7f7a1373289 590 Gene3D G3DSA:1.25.40.10 106 236 2.0E-17 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_00535 60e34f5b776a5dc0cef6a7f7a1373289 590 SMART SM00729 287 520 0.0076 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSH58p_00535 60e34f5b776a5dc0cef6a7f7a1373289 590 Pfam PF13394 4Fe-4S single cluster domain 295 386 8.1E-10 T 14-10-2018 TSH58p_00535 60e34f5b776a5dc0cef6a7f7a1373289 590 Pfam PF13186 Iron-sulfur cluster-binding domain 500 568 4.4E-15 T 14-10-2018 IPR023885 4Fe4S-binding SPASM domain TSH58p_00535 60e34f5b776a5dc0cef6a7f7a1373289 590 Gene3D G3DSA:1.25.40.10 3 105 2.9E-18 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_26490 e919b5c9ccf5e8676efde0d047808736 210 SUPERFAMILY SSF64438 33 182 4.58E-47 T 14-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic TSH58p_26490 e919b5c9ccf5e8676efde0d047808736 210 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 29 182 27.709 T 14-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 TSH58p_26490 e919b5c9ccf5e8676efde0d047808736 210 Pfam PF03975 CheD chemotactic sensory transduction 77 175 8.6E-26 T 14-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 TSH58p_26490 e919b5c9ccf5e8676efde0d047808736 210 Gene3D G3DSA:3.30.1330.200 31 189 8.5E-49 T 14-10-2018 IPR038592 CheD-like superfamily TSH58p_10030 c9250b75ac8a3ef6a420dc3adf2fcf05 256 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 190 207 1.3E-5 T 14-10-2018 TSH58p_10030 c9250b75ac8a3ef6a420dc3adf2fcf05 256 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 228 248 1.3E-5 T 14-10-2018 TSH58p_10030 c9250b75ac8a3ef6a420dc3adf2fcf05 256 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 208 227 1.3E-5 T 14-10-2018 TSH58p_10030 c9250b75ac8a3ef6a420dc3adf2fcf05 256 Gene3D G3DSA:3.30.1330.60 109 250 6.8E-43 T 14-10-2018 IPR036737 OmpA-like domain superfamily TSH58p_10030 c9250b75ac8a3ef6a420dc3adf2fcf05 256 Pfam PF14346 Domain of unknown function (DUF4398) 24 118 7.5E-15 T 14-10-2018 IPR025511 Domain of unknown function DUF4398 TSH58p_10030 c9250b75ac8a3ef6a420dc3adf2fcf05 256 Pfam PF00691 OmpA family 144 239 7.1E-25 T 14-10-2018 IPR006665 OmpA-like domain TSH58p_10030 c9250b75ac8a3ef6a420dc3adf2fcf05 256 PRINTS PR01021 OMPA domain signature 190 206 9.6E-9 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 TSH58p_10030 c9250b75ac8a3ef6a420dc3adf2fcf05 256 PRINTS PR01021 OMPA domain signature 175 190 9.6E-9 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 TSH58p_10030 c9250b75ac8a3ef6a420dc3adf2fcf05 256 PRINTS PR01021 OMPA domain signature 145 167 9.6E-9 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 TSH58p_10030 c9250b75ac8a3ef6a420dc3adf2fcf05 256 SUPERFAMILY SSF103088 136 245 1.06E-37 T 14-10-2018 IPR036737 OmpA-like domain superfamily TSH58p_08125 e995079f670c8afdd19ee2ed64fb060b 215 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 59 175 6.7E-39 T 14-10-2018 IPR012997 Rare lipoprotein A TSH58p_08125 e995079f670c8afdd19ee2ed64fb060b 215 Gene3D G3DSA:2.40.40.10 56 148 6.9E-37 T 14-10-2018 IPR036908 RlpA-like domain superfamily TSH58p_08125 e995079f670c8afdd19ee2ed64fb060b 215 Pfam PF03330 Lytic transglycolase 58 146 5.9E-24 T 14-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain TSH58p_08125 e995079f670c8afdd19ee2ed64fb060b 215 SUPERFAMILY SSF50685 62 145 3.49E-12 T 14-10-2018 IPR036908 RlpA-like domain superfamily TSH58p_08125 e995079f670c8afdd19ee2ed64fb060b 215 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 8 149 21.797 T 14-10-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 TSH58p_30755 b4a5c7e1f21db44d567fb70020679f25 365 Pfam PF02558 Ketopantoate reductase PanE/ApbA 11 151 5.9E-27 T 14-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain TSH58p_30755 b4a5c7e1f21db44d567fb70020679f25 365 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 10 341 1.5E-47 T 14-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 TSH58p_30755 b4a5c7e1f21db44d567fb70020679f25 365 SUPERFAMILY SSF48179 194 340 1.26E-18 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_30755 b4a5c7e1f21db44d567fb70020679f25 365 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 194 339 2.6E-20 T 14-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain TSH58p_30755 b4a5c7e1f21db44d567fb70020679f25 365 SUPERFAMILY SSF51735 10 197 1.97E-13 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_30755 b4a5c7e1f21db44d567fb70020679f25 365 Gene3D G3DSA:1.10.1040.10 195 344 5.3E-21 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSH58p_30755 b4a5c7e1f21db44d567fb70020679f25 365 Gene3D G3DSA:3.40.50.720 10 183 1.0E-35 T 14-10-2018 TSH58p_24085 1cc70480065050583d7b3986a3d9c9cd 268 Gene3D G3DSA:3.30.950.10 138 266 2.9E-40 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 TSH58p_24085 1cc70480065050583d7b3986a3d9c9cd 268 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 102 135 - T 14-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TSH58p_24085 1cc70480065050583d7b3986a3d9c9cd 268 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 24 229 1.2E-47 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 TSH58p_24085 1cc70480065050583d7b3986a3d9c9cd 268 Gene3D G3DSA:3.40.1010.10 15 137 5.5E-40 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 TSH58p_24085 1cc70480065050583d7b3986a3d9c9cd 268 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 22 255 7.9E-83 T 14-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TSH58p_24085 1cc70480065050583d7b3986a3d9c9cd 268 SUPERFAMILY SSF53790 18 261 5.5E-69 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 TSH58p_00745 8b4c320cc2053af7706bd34d439ba76d 67 Pfam PF11450 Protein of unknwon function (DUF3008) 4 59 9.8E-27 T 14-10-2018 IPR021553 Protein of unknwon function DUF3008 TSH58p_30210 4bc602649df5437c0f0fb505cb93b549 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 186 9.0E-5 T 14-10-2018 TSH58p_30210 4bc602649df5437c0f0fb505cb93b549 251 SUPERFAMILY SSF51735 1 250 5.92E-85 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_30210 4bc602649df5437c0f0fb505cb93b549 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.2E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30210 4bc602649df5437c0f0fb505cb93b549 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.2E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30210 4bc602649df5437c0f0fb505cb93b549 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.2E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30210 4bc602649df5437c0f0fb505cb93b549 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 1.2E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30210 4bc602649df5437c0f0fb505cb93b549 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.2E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30210 4bc602649df5437c0f0fb505cb93b549 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.2E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30210 4bc602649df5437c0f0fb505cb93b549 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_30210 4bc602649df5437c0f0fb505cb93b549 251 Gene3D G3DSA:3.40.50.720 1 251 8.1E-90 T 14-10-2018 TSH58p_30210 4bc602649df5437c0f0fb505cb93b549 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 249 3.5E-70 T 14-10-2018 TSH58p_30210 4bc602649df5437c0f0fb505cb93b549 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 3.0E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30210 4bc602649df5437c0f0fb505cb93b549 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 3.0E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30210 4bc602649df5437c0f0fb505cb93b549 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 3.0E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_26410 5ab6dfac9fb16f70e3fac5c35c9acab8 210 TIGRFAM TIGR01583 formate-DH-gamm: formate dehydrogenase, gamma subunit 7 203 3.0E-63 T 14-10-2018 IPR006471 Formate dehydrogenase, gamma subunit GO:0008863|GO:0009326|GO:0016021|GO:0045333 TSH58p_26410 5ab6dfac9fb16f70e3fac5c35c9acab8 210 Gene3D G3DSA:1.20.950.20 1 210 6.8E-67 T 14-10-2018 TSH58p_26410 5ab6dfac9fb16f70e3fac5c35c9acab8 210 Pfam PF01292 Prokaryotic cytochrome b561 10 184 1.7E-19 T 14-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 TSH58p_26410 5ab6dfac9fb16f70e3fac5c35c9acab8 210 SUPERFAMILY SSF81342 4 207 2.12E-51 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 TSH58p_20130 9bda6d0e96489da2bb26deae9b66fe49 238 TIGRFAM TIGR03170 flgA_cterm: flagella basal body P-ring formation protein FlgA 97 230 3.9E-35 T 14-10-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal TSH58p_20130 9bda6d0e96489da2bb26deae9b66fe49 238 SMART SM00858 107 169 5.6E-6 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 TSH58p_20130 9bda6d0e96489da2bb26deae9b66fe49 238 Pfam PF13144 Chaperone for flagella basal body P-ring formation 92 230 3.2E-33 T 14-10-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal TSH58p_20130 9bda6d0e96489da2bb26deae9b66fe49 238 Gene3D G3DSA:2.30.30.760 174 233 1.1E-9 T 14-10-2018 TSH58p_07070 b964a55e0344f75295fe312c0e74e31a 480 Gene3D G3DSA:1.10.760.10 334 439 1.2E-12 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_07070 b964a55e0344f75295fe312c0e74e31a 480 PIRSF PIRSF000018 17 477 3.2E-144 T 14-10-2018 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 TSH58p_07070 b964a55e0344f75295fe312c0e74e31a 480 Gene3D G3DSA:1.10.760.10 1 155 3.1E-11 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_07070 b964a55e0344f75295fe312c0e74e31a 480 Gene3D G3DSA:1.10.760.10 187 297 3.4E-5 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_07070 b964a55e0344f75295fe312c0e74e31a 480 SUPERFAMILY SSF46626 195 307 1.3E-12 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_07070 b964a55e0344f75295fe312c0e74e31a 480 Pfam PF00034 Cytochrome c 49 149 1.6E-7 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_07070 b964a55e0344f75295fe312c0e74e31a 480 SUPERFAMILY SSF46626 355 455 3.48E-15 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_07070 b964a55e0344f75295fe312c0e74e31a 480 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 355 434 1.7E-9 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_07070 b964a55e0344f75295fe312c0e74e31a 480 SUPERFAMILY SSF46626 33 172 2.47E-24 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_01745 2289feadf7c25b0180694d9393c0958a 293 Pfam PF09339 IclR helix-turn-helix domain 39 90 2.3E-15 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TSH58p_01745 2289feadf7c25b0180694d9393c0958a 293 SUPERFAMILY SSF46785 38 110 5.92E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_01745 2289feadf7c25b0180694d9393c0958a 293 Gene3D G3DSA:1.10.10.10 31 108 4.7E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_01745 2289feadf7c25b0180694d9393c0958a 293 Gene3D G3DSA:3.30.450.40 110 282 1.2E-45 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_01745 2289feadf7c25b0180694d9393c0958a 293 Pfam PF01614 Bacterial transcriptional regulator 158 280 1.5E-24 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal TSH58p_01745 2289feadf7c25b0180694d9393c0958a 293 SUPERFAMILY SSF55781 104 280 4.19E-43 T 14-10-2018 TSH58p_01745 2289feadf7c25b0180694d9393c0958a 293 SMART SM00346 37 127 4.7E-25 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TSH58p_16820 c657c6b1e2e4a4b8bfac640bb26ecc58 118 SUPERFAMILY SSF82057 47 118 2.15E-26 T 14-10-2018 TSH58p_16820 c657c6b1e2e4a4b8bfac640bb26ecc58 118 Gene3D G3DSA:2.20.25.10 5 42 9.9E-16 T 14-10-2018 TSH58p_16820 c657c6b1e2e4a4b8bfac640bb26ecc58 118 Gene3D G3DSA:2.30.30.40 47 118 5.2E-33 T 14-10-2018 TSH58p_16820 c657c6b1e2e4a4b8bfac640bb26ecc58 118 Pfam PF03831 PhnA domain 49 118 6.0E-33 T 14-10-2018 IPR013988 PhnA protein, C-terminal TSH58p_16820 c657c6b1e2e4a4b8bfac640bb26ecc58 118 Pfam PF08274 PhnA Zinc-Ribbon 6 31 2.9E-14 T 14-10-2018 IPR013987 PhnA protein, N-terminal TSH58p_16820 c657c6b1e2e4a4b8bfac640bb26ecc58 118 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 6 118 1.2E-42 T 14-10-2018 IPR004624 PhnA protein TSH58p_16820 c657c6b1e2e4a4b8bfac640bb26ecc58 118 SUPERFAMILY SSF57783 6 35 2.38E-12 T 14-10-2018 TSH58p_16945 498ef1028cd42a6511947df89c7f1263 296 Hamap MF_00158 Pantothenate synthetase [panC]. 17 293 38.706 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 TSH58p_16945 498ef1028cd42a6511947df89c7f1263 296 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 39 90 5.0E-8 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TSH58p_16945 498ef1028cd42a6511947df89c7f1263 296 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 18 291 1.1E-86 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 TSH58p_16945 498ef1028cd42a6511947df89c7f1263 296 Gene3D G3DSA:3.40.50.620 9 189 3.5E-69 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_16945 498ef1028cd42a6511947df89c7f1263 296 SUPERFAMILY SSF52374 15 293 6.7E-103 T 14-10-2018 TSH58p_16945 498ef1028cd42a6511947df89c7f1263 296 Gene3D G3DSA:3.30.1300.10 190 296 4.0E-33 T 14-10-2018 TSH58p_16945 498ef1028cd42a6511947df89c7f1263 296 Pfam PF02569 Pantoate-beta-alanine ligase 18 291 9.1E-98 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 TSH58p_03715 146cbec491c131a44958a8c27ec1e160 142 Pfam PF00717 Peptidase S24-like 54 121 2.9E-12 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C TSH58p_03715 146cbec491c131a44958a8c27ec1e160 142 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 62 73 5.7E-8 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 TSH58p_03715 146cbec491c131a44958a8c27ec1e160 142 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 90 102 5.7E-8 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 TSH58p_03715 146cbec491c131a44958a8c27ec1e160 142 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 51 61 5.7E-8 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 TSH58p_03715 146cbec491c131a44958a8c27ec1e160 142 SUPERFAMILY SSF51306 16 138 5.76E-32 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily TSH58p_03715 146cbec491c131a44958a8c27ec1e160 142 Gene3D G3DSA:2.10.109.10 24 141 2.1E-41 T 14-10-2018 TSH58p_03885 fabc4de0bbfe47f10262ec4c2fbae636 472 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 157 439 2.8E-27 T 14-10-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 TSH58p_03885 fabc4de0bbfe47f10262ec4c2fbae636 472 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 15 153 1.8E-33 T 14-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 TSH58p_03885 fabc4de0bbfe47f10262ec4c2fbae636 472 Gene3D G3DSA:3.30.360.30 159 468 5.4E-195 T 14-10-2018 IPR023181 Homospermidine synthase-like, C-terminal KEGG: 00960+2.5.1.44 TSH58p_03885 fabc4de0bbfe47f10262ec4c2fbae636 472 Gene3D G3DSA:3.40.50.720 15 423 5.4E-195 T 14-10-2018 TSH58p_21130 4bc3b39e18c994539665da3e75403c58 479 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 246 253 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 TSH58p_21130 4bc3b39e18c994539665da3e75403c58 479 Pfam PF00171 Aldehyde dehydrogenase family 13 472 1.4E-149 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TSH58p_21130 4bc3b39e18c994539665da3e75403c58 479 Gene3D G3DSA:3.40.605.10 27 468 1.2E-157 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TSH58p_21130 4bc3b39e18c994539665da3e75403c58 479 SUPERFAMILY SSF53720 5 473 1.83E-149 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSH58p_21130 4bc3b39e18c994539665da3e75403c58 479 Gene3D G3DSA:3.40.309.10 250 441 1.2E-157 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TSH58p_02705 d9f361b148ec31a7fae1c134762c3ef8 179 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 131 9.4E-34 T 14-10-2018 TSH58p_02705 d9f361b148ec31a7fae1c134762c3ef8 179 Gene3D G3DSA:3.10.180.10 4 145 3.7E-36 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSH58p_02705 d9f361b148ec31a7fae1c134762c3ef8 179 SUPERFAMILY SSF54593 7 146 1.69E-19 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSH58p_05520 057cc7a835c47e62f71eee62f47a6506 645 SMART SM00382 188 327 1.2E-24 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_05520 057cc7a835c47e62f71eee62f47a6506 645 ProSitePatterns PS00674 AAA-protein family signature. 295 313 - T 14-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TSH58p_05520 057cc7a835c47e62f71eee62f47a6506 645 Pfam PF06480 FtsH Extracellular 9 88 4.2E-10 T 14-10-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 TSH58p_05520 057cc7a835c47e62f71eee62f47a6506 645 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 6 608 37.696 T 14-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 TSH58p_05520 057cc7a835c47e62f71eee62f47a6506 645 Gene3D G3DSA:3.40.50.300 144 324 2.3E-70 T 14-10-2018 TSH58p_05520 057cc7a835c47e62f71eee62f47a6506 645 Gene3D G3DSA:1.10.8.60 326 400 2.2E-29 T 14-10-2018 TSH58p_05520 057cc7a835c47e62f71eee62f47a6506 645 Pfam PF01434 Peptidase family M41 386 595 4.8E-80 T 14-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 TSH58p_05520 057cc7a835c47e62f71eee62f47a6506 645 Gene3D G3DSA:2.40.50.920 28 102 4.6E-9 T 14-10-2018 TSH58p_05520 057cc7a835c47e62f71eee62f47a6506 645 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 192 324 2.2E-45 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSH58p_05520 057cc7a835c47e62f71eee62f47a6506 645 SUPERFAMILY SSF52540 146 395 7.71E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_05520 057cc7a835c47e62f71eee62f47a6506 645 SUPERFAMILY SSF140990 406 606 3.92E-75 T 14-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 TSH58p_05520 057cc7a835c47e62f71eee62f47a6506 645 Gene3D G3DSA:1.20.58.760 401 606 1.2E-73 T 14-10-2018 TSH58p_05520 057cc7a835c47e62f71eee62f47a6506 645 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 104 597 9.8E-239 T 14-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 TSH58p_17100 379bce0f33b4af681ccb601e54a02af0 179 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 76 165 1.2E-27 T 14-10-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 TSH58p_17100 379bce0f33b4af681ccb601e54a02af0 179 Gene3D G3DSA:1.20.120.1630 9 168 2.1E-19 T 14-10-2018 TSH58p_19925 61b073881372256c750384b23610dc20 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 4.0E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_19925 61b073881372256c750384b23610dc20 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 4.0E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_19925 61b073881372256c750384b23610dc20 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 4.0E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_19925 61b073881372256c750384b23610dc20 297 Gene3D G3DSA:3.40.190.10 94 293 2.5E-55 T 14-10-2018 TSH58p_19925 61b073881372256c750384b23610dc20 297 SUPERFAMILY SSF46785 4 114 1.32E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_19925 61b073881372256c750384b23610dc20 297 Gene3D G3DSA:3.40.190.10 166 269 2.5E-55 T 14-10-2018 TSH58p_19925 61b073881372256c750384b23610dc20 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 2.8E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_19925 61b073881372256c750384b23610dc20 297 SUPERFAMILY SSF53850 91 295 2.9E-42 T 14-10-2018 TSH58p_19925 61b073881372256c750384b23610dc20 297 Gene3D G3DSA:1.10.10.10 5 93 1.0E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_19925 61b073881372256c750384b23610dc20 297 Pfam PF03466 LysR substrate binding domain 90 295 3.3E-40 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_13770 d79c0c81a9b8af6549d2a2e4b6118ed0 233 SMART SM00382 26 210 3.8E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_13770 d79c0c81a9b8af6549d2a2e4b6118ed0 233 SUPERFAMILY SSF52540 2 230 3.55E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_13770 d79c0c81a9b8af6549d2a2e4b6118ed0 233 Gene3D G3DSA:3.40.50.300 1 233 8.0E-62 T 14-10-2018 TSH58p_13770 d79c0c81a9b8af6549d2a2e4b6118ed0 233 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_13770 d79c0c81a9b8af6549d2a2e4b6118ed0 233 Pfam PF00005 ABC transporter 19 161 8.1E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_25270 5fb19a5cbb2348a0d5ffbf3351925268 274 Gene3D G3DSA:1.10.443.10 68 254 9.3E-17 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TSH58p_25270 5fb19a5cbb2348a0d5ffbf3351925268 274 SUPERFAMILY SSF56349 2 238 1.21E-25 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TSH58p_25270 5fb19a5cbb2348a0d5ffbf3351925268 274 Pfam PF00589 Phage integrase family 87 226 3.7E-7 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TSH58p_06905 159c78822b2b757c767b905c88a5a680 152 Pfam PF09523 Protein of unknown function (DUF2390) 6 107 4.7E-35 T 14-10-2018 IPR012659 Conserved hypothetical protein CHP02444 TSH58p_06905 159c78822b2b757c767b905c88a5a680 152 TIGRFAM TIGR02444 TIGR02444: TIGR02444 family protein 5 110 1.6E-30 T 14-10-2018 IPR012659 Conserved hypothetical protein CHP02444 TSH58p_12850 e23580bebb8e692e67be1b5a1e23fb2d 203 Pfam PF11136 Protein of unknown function (DUF2889) 13 136 9.7E-47 T 14-10-2018 IPR021312 Protein of unknown function DUF2889 TSH58p_02400 9900c9b8db4bc9d96058a038b136ff99 291 Gene3D G3DSA:3.40.190.100 109 221 1.8E-87 T 14-10-2018 TSH58p_02400 9900c9b8db4bc9d96058a038b136ff99 291 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 26 270 3.5E-66 T 14-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 TSH58p_02400 9900c9b8db4bc9d96058a038b136ff99 291 Gene3D G3DSA:3.40.190.10 28 284 1.8E-87 T 14-10-2018 TSH58p_02400 9900c9b8db4bc9d96058a038b136ff99 291 SUPERFAMILY SSF53850 21 288 1.2E-79 T 14-10-2018 TSH58p_12825 9ab7c5079df9b020bdb5b7d901824451 126 Pfam PF13366 PD-(D/E)XK nuclease superfamily 11 117 1.2E-38 T 14-10-2018 IPR026350 GxxExxY protein TSH58p_12825 9ab7c5079df9b020bdb5b7d901824451 126 TIGRFAM TIGR04256 GxxExxY: GxxExxY protein 12 124 2.3E-40 T 14-10-2018 IPR026350 GxxExxY protein TSH58p_29305 3ffcbb1b87d7881967bf5beb7284ea05 264 Pfam PF00072 Response regulator receiver domain 138 246 3.6E-14 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_29305 3ffcbb1b87d7881967bf5beb7284ea05 264 Gene3D G3DSA:3.40.50.2300 135 259 6.1E-33 T 14-10-2018 TSH58p_29305 3ffcbb1b87d7881967bf5beb7284ea05 264 SMART SM00448 136 246 6.5E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_29305 3ffcbb1b87d7881967bf5beb7284ea05 264 SUPERFAMILY SSF52172 137 250 7.4E-24 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_29305 3ffcbb1b87d7881967bf5beb7284ea05 264 SUPERFAMILY SSF88659 80 134 5.49E-5 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSH58p_29305 3ffcbb1b87d7881967bf5beb7284ea05 264 Gene3D G3DSA:1.20.140.160 3 134 7.6E-30 T 14-10-2018 TSH58p_00500 327c284c0505384e2bea89867a605a78 135 Gene3D G3DSA:2.30.30.240 51 131 1.4E-14 T 14-10-2018 TSH58p_00500 327c284c0505384e2bea89867a605a78 135 Pfam PF05239 PRC-barrel domain 58 117 4.0E-8 T 14-10-2018 IPR027275 PRC-barrel domain TSH58p_00500 327c284c0505384e2bea89867a605a78 135 SUPERFAMILY SSF50346 20 131 2.16E-10 T 14-10-2018 IPR011033 PRC-barrel-like superfamily TSH58p_01900 13dde7e41525ed3a005a5593e36e12b3 202 Pfam PF03358 NADPH-dependent FMN reductase 6 161 4.5E-22 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 TSH58p_01900 13dde7e41525ed3a005a5593e36e12b3 202 SUPERFAMILY SSF52218 1 193 3.73E-24 T 14-10-2018 IPR029039 Flavoprotein-like superfamily TSH58p_01900 13dde7e41525ed3a005a5593e36e12b3 202 Gene3D G3DSA:3.40.50.360 1 199 8.9E-17 T 14-10-2018 IPR029039 Flavoprotein-like superfamily TSH58p_12490 919fd567251caea9a08af59c38a5103e 496 SMART SM00487 52 252 3.9E-59 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSH58p_12490 919fd567251caea9a08af59c38a5103e 496 Pfam PF00271 Helicase conserved C-terminal domain 268 370 1.8E-28 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_12490 919fd567251caea9a08af59c38a5103e 496 SUPERFAMILY SSF52540 106 392 5.35E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_12490 919fd567251caea9a08af59c38a5103e 496 Gene3D G3DSA:3.40.50.300 4 241 1.3E-75 T 14-10-2018 TSH58p_12490 919fd567251caea9a08af59c38a5103e 496 Gene3D G3DSA:3.40.50.300 244 406 1.4E-50 T 14-10-2018 TSH58p_12490 919fd567251caea9a08af59c38a5103e 496 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 184 192 - T 14-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site TSH58p_12490 919fd567251caea9a08af59c38a5103e 496 Pfam PF00270 DEAD/DEAH box helicase 57 224 3.3E-49 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TSH58p_12490 919fd567251caea9a08af59c38a5103e 496 SMART SM00490 289 370 3.8E-33 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_24585 7474f4d48a3639096e8c4e5c91379d2b 308 Pfam PF00892 EamA-like transporter family 16 148 2.3E-16 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_24585 7474f4d48a3639096e8c4e5c91379d2b 308 Pfam PF00892 EamA-like transporter family 160 284 3.3E-6 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_24585 7474f4d48a3639096e8c4e5c91379d2b 308 SUPERFAMILY SSF103481 50 150 7.19E-16 T 14-10-2018 TSH58p_24585 7474f4d48a3639096e8c4e5c91379d2b 308 SUPERFAMILY SSF103481 193 289 2.09E-10 T 14-10-2018 TSH58p_15355 11a0fc992de0817a8aaa9113fc5a94b5 114 SUPERFAMILY SSF48295 17 96 3.56E-20 T 14-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 TSH58p_15355 11a0fc992de0817a8aaa9113fc5a94b5 114 Pfam PF06627 Protein of unknown function (DUF1153) 16 96 6.9E-39 T 14-10-2018 IPR009534 Protein of unknown function DUF1153 TSH58p_15355 11a0fc992de0817a8aaa9113fc5a94b5 114 Gene3D G3DSA:1.10.10.10 16 99 1.2E-36 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_32500 a7c1bea5b1edd589b112032965c39a5d 128 SUPERFAMILY SSF52172 3 123 4.13E-29 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_32500 a7c1bea5b1edd589b112032965c39a5d 128 Gene3D G3DSA:3.40.50.2300 1 125 2.3E-29 T 14-10-2018 TSH58p_32500 a7c1bea5b1edd589b112032965c39a5d 128 Pfam PF00072 Response regulator receiver domain 7 115 2.0E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_32500 a7c1bea5b1edd589b112032965c39a5d 128 SMART SM00448 5 118 4.5E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_11180 0a10d6de42aa7e53bf6d99c8f168b9d3 134 Pfam PF12844 Helix-turn-helix domain 5 58 1.9E-13 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_11180 0a10d6de42aa7e53bf6d99c8f168b9d3 134 SUPERFAMILY SSF47413 2 58 1.41E-11 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_11180 0a10d6de42aa7e53bf6d99c8f168b9d3 134 SMART SM00530 7 63 2.2E-8 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_11180 0a10d6de42aa7e53bf6d99c8f168b9d3 134 Gene3D G3DSA:1.10.260.40 2 79 1.7E-13 T 14-10-2018 TSH58p_19225 4ea4f8f43003dde63be5374d440feedf 264 Gene3D G3DSA:1.10.3700.10 1 224 3.2E-75 T 14-10-2018 IPR023157 AGR-C-984p-like superfamily TSH58p_19225 4ea4f8f43003dde63be5374d440feedf 264 Pfam PF06748 Protein of unknown function (DUF1217) 60 208 5.4E-49 T 14-10-2018 IPR010626 Protein of unknown function DUF1217 TSH58p_19225 4ea4f8f43003dde63be5374d440feedf 264 SUPERFAMILY SSF158837 1 223 1.26E-70 T 14-10-2018 IPR023157 AGR-C-984p-like superfamily TSH58p_01420 24a2bbd96ff59eb63f89e8a1c458a1d0 390 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 222 4.5E-24 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TSH58p_01420 24a2bbd96ff59eb63f89e8a1c458a1d0 390 Gene3D G3DSA:1.10.540.10 1 121 1.3E-27 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TSH58p_01420 24a2bbd96ff59eb63f89e8a1c458a1d0 390 PIRSF PIRSF016578 241 388 3.0E-11 T 14-10-2018 TSH58p_01420 24a2bbd96ff59eb63f89e8a1c458a1d0 390 PIRSF PIRSF016578 134 202 0.039 T 14-10-2018 TSH58p_01420 24a2bbd96ff59eb63f89e8a1c458a1d0 390 PIRSF PIRSF016578 15 110 0.013 T 14-10-2018 TSH58p_01420 24a2bbd96ff59eb63f89e8a1c458a1d0 390 SUPERFAMILY SSF56645 1 231 2.09E-61 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TSH58p_01420 24a2bbd96ff59eb63f89e8a1c458a1d0 390 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 381 2.2E-35 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TSH58p_01420 24a2bbd96ff59eb63f89e8a1c458a1d0 390 Gene3D G3DSA:2.40.110.10 123 238 2.9E-31 T 14-10-2018 TSH58p_01420 24a2bbd96ff59eb63f89e8a1c458a1d0 390 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 119 3.8E-22 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TSH58p_01420 24a2bbd96ff59eb63f89e8a1c458a1d0 390 Gene3D G3DSA:1.20.140.10 239 382 6.2E-38 T 14-10-2018 TSH58p_01420 24a2bbd96ff59eb63f89e8a1c458a1d0 390 SUPERFAMILY SSF47203 234 387 1.16E-41 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TSH58p_01420 24a2bbd96ff59eb63f89e8a1c458a1d0 390 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 342 361 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TSH58p_20745 be12bba983987b6cd0a5961284547e87 70 Pfam PF04964 Flp/Fap pilin component 19 62 5.9E-14 T 14-10-2018 IPR007047 Flp/Fap pilin component TSH58p_32055 8984f87bb800acfd5b9276c1a58671c4 408 Pfam PF00970 Oxidoreductase FAD-binding domain 161 261 1.0E-5 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 TSH58p_32055 8984f87bb800acfd5b9276c1a58671c4 408 Gene3D G3DSA:2.40.30.10 154 263 9.6E-33 T 14-10-2018 TSH58p_32055 8984f87bb800acfd5b9276c1a58671c4 408 SUPERFAMILY SSF46458 5 136 1.61E-33 T 14-10-2018 IPR009050 Globin-like superfamily TSH58p_32055 8984f87bb800acfd5b9276c1a58671c4 408 Pfam PF00042 Globin 11 106 1.1E-4 T 14-10-2018 IPR000971 Globin GO:0020037 TSH58p_32055 8984f87bb800acfd5b9276c1a58671c4 408 Pfam PF00175 Oxidoreductase NAD-binding domain 273 379 3.5E-13 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 TSH58p_32055 8984f87bb800acfd5b9276c1a58671c4 408 Gene3D G3DSA:1.10.490.10 4 147 3.2E-47 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 TSH58p_32055 8984f87bb800acfd5b9276c1a58671c4 408 SUPERFAMILY SSF63380 154 263 8.05E-28 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TSH58p_32055 8984f87bb800acfd5b9276c1a58671c4 408 PRINTS PR00410 Phenol hydroxylase reductase family signature 367 375 3.7E-7 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TSH58p_32055 8984f87bb800acfd5b9276c1a58671c4 408 PRINTS PR00410 Phenol hydroxylase reductase family signature 188 200 3.7E-7 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TSH58p_32055 8984f87bb800acfd5b9276c1a58671c4 408 PRINTS PR00410 Phenol hydroxylase reductase family signature 272 291 3.7E-7 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TSH58p_32055 8984f87bb800acfd5b9276c1a58671c4 408 SUPERFAMILY SSF52343 264 402 4.85E-35 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TSH58p_32055 8984f87bb800acfd5b9276c1a58671c4 408 Gene3D G3DSA:3.40.50.80 266 404 4.4E-30 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TSH58p_11330 6463c4d077f074ef32d9db0a5334a9c6 274 Gene3D G3DSA:3.40.630.30 20 166 3.9E-18 T 14-10-2018 TSH58p_11330 6463c4d077f074ef32d9db0a5334a9c6 274 SUPERFAMILY SSF55729 19 240 8.36E-39 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_11330 6463c4d077f074ef32d9db0a5334a9c6 274 Pfam PF13444 Acetyltransferase (GNAT) domain 36 143 6.1E-32 T 14-10-2018 TSH58p_14260 09fd4fcb5b370d1dba6dca18ef16383a 474 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 288 440 1.0E-27 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_14260 09fd4fcb5b370d1dba6dca18ef16383a 474 SUPERFAMILY SSF58104 193 463 5.89E-50 T 14-10-2018 TSH58p_14260 09fd4fcb5b370d1dba6dca18ef16383a 474 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 231 260 1.1E-21 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_14260 09fd4fcb5b370d1dba6dca18ef16383a 474 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 308 335 1.1E-21 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_14260 09fd4fcb5b370d1dba6dca18ef16383a 474 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 337 366 1.1E-21 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_14260 09fd4fcb5b370d1dba6dca18ef16383a 474 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 385 414 1.1E-21 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_14260 09fd4fcb5b370d1dba6dca18ef16383a 474 Gene3D G3DSA:1.10.490.10 24 179 4.4E-42 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 TSH58p_14260 09fd4fcb5b370d1dba6dca18ef16383a 474 Pfam PF11563 Protoglobin 33 183 4.6E-34 T 14-10-2018 TSH58p_14260 09fd4fcb5b370d1dba6dca18ef16383a 474 SMART SM00283 210 464 1.1E-28 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_14260 09fd4fcb5b370d1dba6dca18ef16383a 474 Gene3D G3DSA:1.10.287.950 182 473 9.8E-48 T 14-10-2018 TSH58p_14260 09fd4fcb5b370d1dba6dca18ef16383a 474 SUPERFAMILY SSF46458 28 178 3.6E-35 T 14-10-2018 IPR009050 Globin-like superfamily TSH58p_10665 5e72cb03d59c482495af16ebf1b3c44c 273 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 198 8.2E-27 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 TSH58p_10665 5e72cb03d59c482495af16ebf1b3c44c 273 SUPERFAMILY SSF53790 1 215 1.18E-75 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 TSH58p_10665 5e72cb03d59c482495af16ebf1b3c44c 273 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 1 217 34.577 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 TSH58p_10665 5e72cb03d59c482495af16ebf1b3c44c 273 Gene3D G3DSA:3.30.950.10 106 222 1.8E-37 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 TSH58p_10665 5e72cb03d59c482495af16ebf1b3c44c 273 PIRSF PIRSF005917 1 270 3.7E-95 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 TSH58p_10665 5e72cb03d59c482495af16ebf1b3c44c 273 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 1 265 3.9E-71 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 TSH58p_10665 5e72cb03d59c482495af16ebf1b3c44c 273 Gene3D G3DSA:3.40.1010.10 1 105 1.7E-38 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 TSH58p_00690 143ccf70f0c4d2a88209d07ac0f4d3ab 188 SUPERFAMILY SSF52540 5 177 3.52E-22 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_00690 143ccf70f0c4d2a88209d07ac0f4d3ab 188 Pfam PF13521 AAA domain 9 172 1.3E-43 T 14-10-2018 IPR038727 NadR/Ttd14, AAA domain TSH58p_00690 143ccf70f0c4d2a88209d07ac0f4d3ab 188 Gene3D G3DSA:3.40.50.300 2 182 3.2E-6 T 14-10-2018 TSH58p_04575 8f9a86f6d1ff02731efbfca9f465b1bd 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 294 2.4E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_04575 8f9a86f6d1ff02731efbfca9f465b1bd 307 SUPERFAMILY SSF161098 13 305 5.89E-59 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_13975 2578710e28d1e9df0b10a05a7ffd92e2 282 Gene3D G3DSA:3.30.750.160 20 202 3.7E-91 T 14-10-2018 TSH58p_13975 2578710e28d1e9df0b10a05a7ffd92e2 282 SUPERFAMILY SSF55811 88 262 7.85E-17 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TSH58p_13975 2578710e28d1e9df0b10a05a7ffd92e2 282 Gene3D G3DSA:3.90.79.10 114 277 3.7E-91 T 14-10-2018 TSH58p_13975 2578710e28d1e9df0b10a05a7ffd92e2 282 Pfam PF15916 Domain of unknown function (DUF4743) 3 114 5.3E-22 T 14-10-2018 IPR031804 Domain of unknown function DUF4743 TSH58p_19545 ed7d87c7f1600bca5c9c5f84a235e836 341 Gene3D G3DSA:3.40.50.2300 169 335 2.8E-78 T 14-10-2018 TSH58p_19545 ed7d87c7f1600bca5c9c5f84a235e836 341 SMART SM00354 12 81 7.2E-29 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TSH58p_19545 ed7d87c7f1600bca5c9c5f84a235e836 341 SUPERFAMILY SSF47413 12 69 3.38E-15 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_19545 ed7d87c7f1600bca5c9c5f84a235e836 341 Pfam PF13377 Periplasmic binding protein-like domain 177 338 1.7E-37 T 14-10-2018 TSH58p_19545 ed7d87c7f1600bca5c9c5f84a235e836 341 SUPERFAMILY SSF53822 69 326 4.71E-68 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_19545 ed7d87c7f1600bca5c9c5f84a235e836 341 Gene3D G3DSA:3.40.50.2300 72 330 2.8E-78 T 14-10-2018 TSH58p_19545 ed7d87c7f1600bca5c9c5f84a235e836 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 15 33 - T 14-10-2018 TSH58p_19545 ed7d87c7f1600bca5c9c5f84a235e836 341 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 3.8E-5 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TSH58p_19545 ed7d87c7f1600bca5c9c5f84a235e836 341 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 24 34 3.8E-5 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TSH58p_19545 ed7d87c7f1600bca5c9c5f84a235e836 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 15 58 4.1E-16 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TSH58p_19545 ed7d87c7f1600bca5c9c5f84a235e836 341 Gene3D G3DSA:1.10.260.40 12 68 2.6E-20 T 14-10-2018 TSH58p_06180 c4ddbe8b22bfd28d827174096cd16f56 133 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 10 121 3.7E-21 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 TSH58p_06180 c4ddbe8b22bfd28d827174096cd16f56 133 TIGRFAM TIGR00494 crcB: protein CrcB 10 123 8.4E-25 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 TSH58p_06180 c4ddbe8b22bfd28d827174096cd16f56 133 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 8 126 18.666 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 TSH58p_31000 bffef4dbf41a6e549436adf02bcc606b 1223 SMART SM00073 1116 1214 0.0079 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TSH58p_31000 bffef4dbf41a6e549436adf02bcc606b 1223 Gene3D G3DSA:1.10.287.130 507 586 3.0E-25 T 14-10-2018 TSH58p_31000 bffef4dbf41a6e549436adf02bcc606b 1223 PRINTS PR00344 Bacterial sensor protein C-terminal signature 694 704 2.4E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_31000 bffef4dbf41a6e549436adf02bcc606b 1223 PRINTS PR00344 Bacterial sensor protein C-terminal signature 711 729 2.4E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_31000 bffef4dbf41a6e549436adf02bcc606b 1223 PRINTS PR00344 Bacterial sensor protein C-terminal signature 676 690 2.4E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_31000 bffef4dbf41a6e549436adf02bcc606b 1223 PRINTS PR00344 Bacterial sensor protein C-terminal signature 735 748 2.4E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_31000 bffef4dbf41a6e549436adf02bcc606b 1223 Gene3D G3DSA:3.40.50.12740 940 1106 3.1E-38 T 14-10-2018 TSH58p_31000 bffef4dbf41a6e549436adf02bcc606b 1223 SUPERFAMILY SSF47384 507 588 4.12E-21 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_31000 bffef4dbf41a6e549436adf02bcc606b 1223 Pfam PF01627 Hpt domain 1128 1203 4.7E-9 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TSH58p_31000 bffef4dbf41a6e549436adf02bcc606b 1223 Gene3D G3DSA:1.10.8.500 453 504 4.9E-11 T 14-10-2018 TSH58p_31000 bffef4dbf41a6e549436adf02bcc606b 1223 Pfam PF00072 Response regulator receiver domain 942 1063 3.6E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_31000 bffef4dbf41a6e549436adf02bcc606b 1223 Gene3D G3DSA:1.20.120.160 1107 1218 2.5E-12 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_31000 bffef4dbf41a6e549436adf02bcc606b 1223 Pfam PF00512 His Kinase A (phospho-acceptor) domain 521 586 1.4E-17 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_31000 bffef4dbf41a6e549436adf02bcc606b 1223 SMART SM00448 940 1063 1.3E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_31000 bffef4dbf41a6e549436adf02bcc606b 1223 Pfam PF00672 HAMP domain 453 501 5.1E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_31000 bffef4dbf41a6e549436adf02bcc606b 1223 SUPERFAMILY SSF158472 453 502 5.62E-7 T 14-10-2018 TSH58p_31000 bffef4dbf41a6e549436adf02bcc606b 1223 SMART SM00387 633 751 1.3E-38 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_31000 bffef4dbf41a6e549436adf02bcc606b 1223 SUPERFAMILY SSF52172 941 1073 3.27E-34 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_31000 bffef4dbf41a6e549436adf02bcc606b 1223 SMART SM00304 453 506 7.4E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_31000 bffef4dbf41a6e549436adf02bcc606b 1223 SMART SM00388 521 586 5.5E-22 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_31000 bffef4dbf41a6e549436adf02bcc606b 1223 Gene3D G3DSA:3.30.565.10 587 753 1.7E-51 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_31000 bffef4dbf41a6e549436adf02bcc606b 1223 SUPERFAMILY SSF55874 575 750 8.64E-46 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_31000 bffef4dbf41a6e549436adf02bcc606b 1223 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 633 749 1.8E-28 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_31000 bffef4dbf41a6e549436adf02bcc606b 1223 SUPERFAMILY SSF47226 1101 1210 1.7E-16 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_22275 c8db72ad1e74937a589845a016e0f05e 574 Gene3D G3DSA:2.40.420.20 266 563 9.0E-30 T 14-10-2018 TSH58p_22275 c8db72ad1e74937a589845a016e0f05e 574 SUPERFAMILY SSF111369 311 435 3.4E-7 T 14-10-2018 TSH58p_22275 c8db72ad1e74937a589845a016e0f05e 574 Gene3D G3DSA:2.40.30.170 278 503 9.0E-30 T 14-10-2018 TSH58p_22275 c8db72ad1e74937a589845a016e0f05e 574 Gene3D G3DSA:1.10.287.470 329 395 9.0E-30 T 14-10-2018 TSH58p_22275 c8db72ad1e74937a589845a016e0f05e 574 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 276 451 3.7E-9 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain TSH58p_22275 c8db72ad1e74937a589845a016e0f05e 574 Gene3D G3DSA:2.40.50.100 292 428 9.0E-30 T 14-10-2018 TSH58p_10370 b6a7394eabcaa8f05495ea647adf92ef 778 SUPERFAMILY SSF50182 593 656 6.54E-11 T 14-10-2018 IPR010920 LSM domain superfamily TSH58p_10370 b6a7394eabcaa8f05495ea647adf92ef 778 SUPERFAMILY SSF82689 658 761 2.35E-13 T 14-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 TSH58p_10370 b6a7394eabcaa8f05495ea647adf92ef 778 Gene3D G3DSA:3.30.70.100 660 750 1.2E-23 T 14-10-2018 TSH58p_10370 b6a7394eabcaa8f05495ea647adf92ef 778 Pfam PF00924 Mechanosensitive ion channel 550 751 1.8E-39 T 14-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 TSH58p_10370 b6a7394eabcaa8f05495ea647adf92ef 778 SUPERFAMILY SSF82861 512 591 6.28E-13 T 14-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 TSH58p_10370 b6a7394eabcaa8f05495ea647adf92ef 778 Gene3D G3DSA:2.30.30.60 609 658 4.9E-13 T 14-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily TSH58p_26860 cd8341572723c9455babb54e459e0e5c 302 SUPERFAMILY SSF53850 91 295 8.32E-35 T 14-10-2018 TSH58p_26860 cd8341572723c9455babb54e459e0e5c 302 Gene3D G3DSA:3.40.190.10 168 269 1.1E-50 T 14-10-2018 TSH58p_26860 cd8341572723c9455babb54e459e0e5c 302 Gene3D G3DSA:3.40.190.10 92 293 1.1E-50 T 14-10-2018 TSH58p_26860 cd8341572723c9455babb54e459e0e5c 302 Gene3D G3DSA:1.10.10.10 1 86 8.5E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_26860 cd8341572723c9455babb54e459e0e5c 302 Pfam PF03466 LysR substrate binding domain 93 298 9.2E-23 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_26860 cd8341572723c9455babb54e459e0e5c 302 SUPERFAMILY SSF46785 3 82 8.71E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_26860 cd8341572723c9455babb54e459e0e5c 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 4.5E-15 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_07080 3502ae7841573e64f0df8d1f2c3677dd 743 SMART SM01008 209 289 3.1E-18 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead TSH58p_07080 3502ae7841573e64f0df8d1f2c3677dd 743 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 599 684 4.5E-15 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 TSH58p_07080 3502ae7841573e64f0df8d1f2c3677dd 743 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 318 565 1.1E-23 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 TSH58p_07080 3502ae7841573e64f0df8d1f2c3677dd 743 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 51 173 1.6E-26 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 TSH58p_07080 3502ae7841573e64f0df8d1f2c3677dd 743 Gene3D G3DSA:3.30.365.10 319 561 5.5E-44 T 14-10-2018 TSH58p_07080 3502ae7841573e64f0df8d1f2c3677dd 743 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 209 258 2.2E-6 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead TSH58p_07080 3502ae7841573e64f0df8d1f2c3677dd 743 PIRSF PIRSF036389 2 739 1.5E-212 T 14-10-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related TSH58p_07080 3502ae7841573e64f0df8d1f2c3677dd 743 Gene3D G3DSA:3.30.365.10 47 181 1.5E-36 T 14-10-2018 TSH58p_07080 3502ae7841573e64f0df8d1f2c3677dd 743 Gene3D G3DSA:3.30.365.10 338 430 5.5E-44 T 14-10-2018 TSH58p_07080 3502ae7841573e64f0df8d1f2c3677dd 743 SUPERFAMILY SSF56003 6 242 4.45E-41 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 TSH58p_07080 3502ae7841573e64f0df8d1f2c3677dd 743 Gene3D G3DSA:3.30.365.10 588 741 3.4E-37 T 14-10-2018 TSH58p_07080 3502ae7841573e64f0df8d1f2c3677dd 743 Gene3D G3DSA:3.90.1170.50 182 286 4.2E-17 T 14-10-2018 TSH58p_07080 3502ae7841573e64f0df8d1f2c3677dd 743 SUPERFAMILY SSF56003 318 737 3.02E-112 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 TSH58p_32205 74a18729a366b57dd15e548d42fe6efa 335 SUPERFAMILY SSF53822 67 333 5.44E-53 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_32205 74a18729a366b57dd15e548d42fe6efa 335 SMART SM00354 7 77 1.7E-17 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TSH58p_32205 74a18729a366b57dd15e548d42fe6efa 335 Gene3D G3DSA:3.40.50.2300 62 310 1.4E-60 T 14-10-2018 TSH58p_32205 74a18729a366b57dd15e548d42fe6efa 335 Gene3D G3DSA:3.40.50.2300 165 293 1.4E-60 T 14-10-2018 TSH58p_32205 74a18729a366b57dd15e548d42fe6efa 335 Pfam PF00356 Bacterial regulatory proteins, lacI family 12 54 2.4E-12 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TSH58p_32205 74a18729a366b57dd15e548d42fe6efa 335 SUPERFAMILY SSF47413 6 66 4.65E-16 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_32205 74a18729a366b57dd15e548d42fe6efa 335 Gene3D G3DSA:1.10.260.40 1 61 4.4E-19 T 14-10-2018 TSH58p_32205 74a18729a366b57dd15e548d42fe6efa 335 Pfam PF13377 Periplasmic binding protein-like domain 174 332 4.0E-31 T 14-10-2018 TSH58p_01440 adadcfb44b414ad16ee5df6830f607bc 302 SUPERFAMILY SSF55166 63 301 9.42E-89 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSH58p_01440 adadcfb44b414ad16ee5df6830f607bc 302 Gene3D G3DSA:3.30.1380.10 55 302 2.8E-88 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSH58p_01440 adadcfb44b414ad16ee5df6830f607bc 302 PIRSF PIRSF018455 30 302 2.0E-95 T 14-10-2018 IPR005073 Peptidase M74, penicillin-insensitive murein endopeptidase GO:0004252|GO:0006508|GO:0030288 TSH58p_01440 adadcfb44b414ad16ee5df6830f607bc 302 Pfam PF03411 Penicillin-insensitive murein endopeptidase 66 299 8.6E-92 T 14-10-2018 IPR005073 Peptidase M74, penicillin-insensitive murein endopeptidase GO:0004252|GO:0006508|GO:0030288 TSH58p_05450 89ac846c1003527ceb2aed48d1b35435 100 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 22 94 2.8E-27 T 14-10-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 TSH58p_05450 89ac846c1003527ceb2aed48d1b35435 100 Gene3D G3DSA:2.30.330.10 12 100 2.5E-25 T 14-10-2018 IPR036429 SpoA-like superfamily TSH58p_05450 89ac846c1003527ceb2aed48d1b35435 100 PRINTS PR00956 Flagellar motor switch protein FliN signature 55 68 4.2E-18 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 TSH58p_05450 89ac846c1003527ceb2aed48d1b35435 100 PRINTS PR00956 Flagellar motor switch protein FliN signature 68 83 4.2E-18 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 TSH58p_05450 89ac846c1003527ceb2aed48d1b35435 100 PRINTS PR00956 Flagellar motor switch protein FliN signature 39 55 4.2E-18 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 TSH58p_05450 89ac846c1003527ceb2aed48d1b35435 100 PRINTS PR00956 Flagellar motor switch protein FliN signature 22 38 4.2E-18 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 TSH58p_05450 89ac846c1003527ceb2aed48d1b35435 100 SUPERFAMILY SSF101801 22 97 6.54E-21 T 14-10-2018 IPR036429 SpoA-like superfamily TSH58p_05450 89ac846c1003527ceb2aed48d1b35435 100 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 23 92 6.4E-22 T 14-10-2018 IPR001543 Surface presentation of antigen (SpoA) TSH58p_24165 7e289779b2024eada27bf6ef4f0410c8 337 Gene3D G3DSA:3.40.50.2000 134 312 2.1E-40 T 14-10-2018 TSH58p_24165 7e289779b2024eada27bf6ef4f0410c8 337 Gene3D G3DSA:3.40.50.2000 1 105 1.8E-15 T 14-10-2018 TSH58p_24165 7e289779b2024eada27bf6ef4f0410c8 337 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 118 283 6.9E-27 T 14-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 TSH58p_24165 7e289779b2024eada27bf6ef4f0410c8 337 SUPERFAMILY SSF53756 2 311 5.76E-63 T 14-10-2018 TSH58p_11870 b9d69d075328fd476579e402053f31df 271 Gene3D G3DSA:3.60.21.10 4 261 2.4E-19 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like TSH58p_11870 b9d69d075328fd476579e402053f31df 271 SUPERFAMILY SSF56300 11 256 1.28E-15 T 14-10-2018 TSH58p_07885 d95efce33e9013ea0ff99e1e502c905d 250 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 14 248 4.5E-59 T 14-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 TSH58p_07885 d95efce33e9013ea0ff99e1e502c905d 250 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 148 247 1.9E-31 T 14-10-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 TSH58p_07885 d95efce33e9013ea0ff99e1e502c905d 250 Gene3D G3DSA:2.160.20.70 143 250 4.2E-32 T 14-10-2018 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 TSH58p_07885 d95efce33e9013ea0ff99e1e502c905d 250 Pfam PF05209 Septum formation inhibitor MinC, N-terminal domain 14 105 4.3E-14 T 14-10-2018 IPR007874 Septum formation inhibitor MinC, N-terminal GO:0051302 TSH58p_07885 d95efce33e9013ea0ff99e1e502c905d 250 SUPERFAMILY SSF63848 146 249 3.27E-31 T 14-10-2018 IPR036145 Septum formation inhibitor MinC, C-terminal domain superfamily GO:0000902 TSH58p_07885 d95efce33e9013ea0ff99e1e502c905d 250 Gene3D G3DSA:3.30.750.120 8 125 4.0E-25 T 14-10-2018 IPR038061 MinC, Proteobacteria, N-terminal domain superfamily TSH58p_07885 d95efce33e9013ea0ff99e1e502c905d 250 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 13 250 24.358 T 14-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 TSH58p_11950 c1fe543cf0770f0ebb4a5ee9713fab6a 474 Pfam PF05050 Methyltransferase FkbM domain 307 442 6.1E-12 T 14-10-2018 IPR006342 Methyltransferase FkbM TSH58p_11950 c1fe543cf0770f0ebb4a5ee9713fab6a 474 SUPERFAMILY SSF53448 69 227 3.0E-14 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_11950 c1fe543cf0770f0ebb4a5ee9713fab6a 474 Gene3D G3DSA:3.90.550.10 76 235 8.4E-10 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_11950 c1fe543cf0770f0ebb4a5ee9713fab6a 474 Gene3D G3DSA:3.40.50.150 294 450 3.9E-30 T 14-10-2018 TSH58p_11950 c1fe543cf0770f0ebb4a5ee9713fab6a 474 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 305 438 4.6E-22 T 14-10-2018 IPR006342 Methyltransferase FkbM TSH58p_11950 c1fe543cf0770f0ebb4a5ee9713fab6a 474 SUPERFAMILY SSF53335 266 457 1.88E-42 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_03115 6f20ee637bb7e3ea953bc5197b054642 285 Gene3D G3DSA:3.90.1530.30 53 115 5.8E-17 T 14-10-2018 TSH58p_03115 6f20ee637bb7e3ea953bc5197b054642 285 SUPERFAMILY SSF110849 40 130 6.1E-23 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily TSH58p_03115 6f20ee637bb7e3ea953bc5197b054642 285 Pfam PF02195 ParB-like nuclease domain 41 127 1.7E-21 T 14-10-2018 IPR003115 ParB/Sulfiredoxin TSH58p_03115 6f20ee637bb7e3ea953bc5197b054642 285 SUPERFAMILY SSF109709 121 225 3.53E-21 T 14-10-2018 TSH58p_03115 6f20ee637bb7e3ea953bc5197b054642 285 SMART SM00470 40 128 3.3E-23 T 14-10-2018 IPR003115 ParB/Sulfiredoxin TSH58p_03115 6f20ee637bb7e3ea953bc5197b054642 285 Gene3D G3DSA:1.10.10.2830 116 228 5.0E-23 T 14-10-2018 TSH58p_03115 6f20ee637bb7e3ea953bc5197b054642 285 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 38 201 2.9E-37 T 14-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 TSH58p_28130 7961f8ff49c6f7e8accc9937b01bc8b6 594 Gene3D G3DSA:1.20.1560.10 150 367 9.2E-6 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_28130 7961f8ff49c6f7e8accc9937b01bc8b6 594 Gene3D G3DSA:3.40.50.300 382 590 2.8E-42 T 14-10-2018 TSH58p_28130 7961f8ff49c6f7e8accc9937b01bc8b6 594 ProSitePatterns PS00211 ABC transporters family signature. 511 525 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_28130 7961f8ff49c6f7e8accc9937b01bc8b6 594 Pfam PF00005 ABC transporter 407 539 1.0E-17 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_28130 7961f8ff49c6f7e8accc9937b01bc8b6 594 SMART SM00382 413 586 4.5E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_28130 7961f8ff49c6f7e8accc9937b01bc8b6 594 Pfam PF06472 ABC transporter transmembrane region 2 24 315 3.9E-70 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TSH58p_28130 7961f8ff49c6f7e8accc9937b01bc8b6 594 SUPERFAMILY SSF90123 44 523 8.63E-26 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_28130 7961f8ff49c6f7e8accc9937b01bc8b6 594 SUPERFAMILY SSF52540 384 580 4.49E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_31800 25be31e33f72400c570d24ed0e8e940e 213 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 2 207 37.873 T 14-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 TSH58p_31800 25be31e33f72400c570d24ed0e8e940e 213 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 4 192 2.9E-64 T 14-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 TSH58p_31800 25be31e33f72400c570d24ed0e8e940e 213 SUPERFAMILY SSF52016 3 198 3.92E-50 T 14-10-2018 TSH58p_31800 25be31e33f72400c570d24ed0e8e940e 213 Pfam PF00694 Aconitase C-terminal domain 8 124 5.4E-31 T 14-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 TSH58p_31800 25be31e33f72400c570d24ed0e8e940e 213 Gene3D G3DSA:3.20.19.10 1 181 1.2E-65 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 TSH58p_00065 8fbbb784323489fc1890a7d201a4adde 496 Gene3D G3DSA:3.30.450.20 142 258 2.2E-26 T 14-10-2018 TSH58p_00065 8fbbb784323489fc1890a7d201a4adde 496 SUPERFAMILY SSF55785 22 125 2.79E-17 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_00065 8fbbb784323489fc1890a7d201a4adde 496 SUPERFAMILY SSF58104 266 494 4.45E-49 T 14-10-2018 TSH58p_00065 8fbbb784323489fc1890a7d201a4adde 496 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 333 484 6.1E-28 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_00065 8fbbb784323489fc1890a7d201a4adde 496 SMART SM00086 207 249 2.2E-8 T 14-10-2018 IPR001610 PAC motif TSH58p_00065 8fbbb784323489fc1890a7d201a4adde 496 SMART SM00086 85 127 9.2 T 14-10-2018 IPR001610 PAC motif TSH58p_00065 8fbbb784323489fc1890a7d201a4adde 496 Gene3D G3DSA:3.30.450.20 7 141 2.1E-16 T 14-10-2018 TSH58p_00065 8fbbb784323489fc1890a7d201a4adde 496 SMART SM00091 12 83 9.8 T 14-10-2018 IPR000014 PAS domain TSH58p_00065 8fbbb784323489fc1890a7d201a4adde 496 SMART SM00091 134 201 0.056 T 14-10-2018 IPR000014 PAS domain TSH58p_00065 8fbbb784323489fc1890a7d201a4adde 496 SUPERFAMILY SSF55785 144 250 2.27E-28 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_00065 8fbbb784323489fc1890a7d201a4adde 496 SMART SM00283 245 495 1.8E-32 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_00065 8fbbb784323489fc1890a7d201a4adde 496 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 382 411 3.3E-18 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_00065 8fbbb784323489fc1890a7d201a4adde 496 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 353 380 3.3E-18 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_00065 8fbbb784323489fc1890a7d201a4adde 496 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 276 305 3.3E-18 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_00065 8fbbb784323489fc1890a7d201a4adde 496 Gene3D G3DSA:1.10.287.950 283 496 1.8E-41 T 14-10-2018 TSH58p_00065 8fbbb784323489fc1890a7d201a4adde 496 Pfam PF13426 PAS domain 24 126 3.7E-11 T 14-10-2018 IPR000014 PAS domain TSH58p_00065 8fbbb784323489fc1890a7d201a4adde 496 Pfam PF08447 PAS fold 157 242 1.5E-16 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 TSH58p_00065 8fbbb784323489fc1890a7d201a4adde 496 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 140 253 1.8E-19 T 14-10-2018 IPR000014 PAS domain TSH58p_00065 8fbbb784323489fc1890a7d201a4adde 496 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 20 129 2.2E-7 T 14-10-2018 IPR000014 PAS domain TSH58p_20370 5b138b7fa660f74caae945086bd335eb 245 Gene3D G3DSA:2.40.500.20 126 245 9.9E-43 T 14-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSH58p_20370 5b138b7fa660f74caae945086bd335eb 245 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 132 234 3.0E-35 T 14-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSH58p_20370 5b138b7fa660f74caae945086bd335eb 245 SUPERFAMILY SSF54719 125 239 2.1E-41 T 14-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSH58p_20370 5b138b7fa660f74caae945086bd335eb 245 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 38 124 1.0E-28 T 14-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSH58p_20370 5b138b7fa660f74caae945086bd335eb 245 SUPERFAMILY SSF46609 37 126 3.67E-35 T 14-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSH58p_20370 5b138b7fa660f74caae945086bd335eb 245 PRINTS PR01703 Manganese superoxide dismutase signature 161 169 5.5E-23 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSH58p_20370 5b138b7fa660f74caae945086bd335eb 245 PRINTS PR01703 Manganese superoxide dismutase signature 62 75 5.5E-23 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSH58p_20370 5b138b7fa660f74caae945086bd335eb 245 PRINTS PR01703 Manganese superoxide dismutase signature 108 121 5.5E-23 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSH58p_20370 5b138b7fa660f74caae945086bd335eb 245 PRINTS PR01703 Manganese superoxide dismutase signature 199 211 5.5E-23 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSH58p_20370 5b138b7fa660f74caae945086bd335eb 245 PRINTS PR01703 Manganese superoxide dismutase signature 41 52 5.5E-23 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSH58p_20370 5b138b7fa660f74caae945086bd335eb 245 PIRSF PIRSF000349 14 243 1.8E-77 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSH58p_20370 5b138b7fa660f74caae945086bd335eb 245 Gene3D G3DSA:1.10.287.990 55 125 1.1E-29 T 14-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSH58p_20370 5b138b7fa660f74caae945086bd335eb 245 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 201 208 - T 14-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSH58p_07010 ca741f219ee5dfdc66fc33f37b2d2b3a 256 Gene3D G3DSA:3.20.20.410 2 246 1.3E-55 T 14-10-2018 IPR036520 UPF0759 superfamily TSH58p_07010 ca741f219ee5dfdc66fc33f37b2d2b3a 256 SUPERFAMILY SSF117396 8 245 5.49E-67 T 14-10-2018 IPR036520 UPF0759 superfamily TSH58p_07010 ca741f219ee5dfdc66fc33f37b2d2b3a 256 Pfam PF01904 Protein of unknown function DUF72 30 242 9.9E-50 T 14-10-2018 IPR002763 Protein of unknown function DUF72 TSH58p_16370 6c937453c609bf80c6d8ce005d3109e5 309 SUPERFAMILY SSF103481 192 294 1.83E-12 T 14-10-2018 TSH58p_16370 6c937453c609bf80c6d8ce005d3109e5 309 Pfam PF00892 EamA-like transporter family 158 291 2.0E-19 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_16370 6c937453c609bf80c6d8ce005d3109e5 309 Pfam PF00892 EamA-like transporter family 10 144 2.1E-9 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_03340 063ddafc50b815de8dfe6addf2894896 203 Gene3D G3DSA:3.40.50.150 10 190 6.7E-23 T 14-10-2018 TSH58p_03340 063ddafc50b815de8dfe6addf2894896 203 Pfam PF13489 Methyltransferase domain 34 149 2.0E-11 T 14-10-2018 TSH58p_03340 063ddafc50b815de8dfe6addf2894896 203 SUPERFAMILY SSF53335 26 184 2.87E-23 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_17855 115df81854186b64b85ce3af81fd33e6 378 SUPERFAMILY SSF53756 10 374 1.75E-63 T 14-10-2018 TSH58p_17855 115df81854186b64b85ce3af81fd33e6 378 Pfam PF13439 Glycosyltransferase Family 4 23 184 3.8E-18 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TSH58p_17855 115df81854186b64b85ce3af81fd33e6 378 Pfam PF00534 Glycosyl transferases group 1 198 354 1.4E-22 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 TSH58p_17855 115df81854186b64b85ce3af81fd33e6 378 Gene3D G3DSA:3.40.50.2000 183 355 6.5E-55 T 14-10-2018 TSH58p_17855 115df81854186b64b85ce3af81fd33e6 378 Gene3D G3DSA:3.40.50.2000 22 371 6.5E-55 T 14-10-2018 TSH58p_06420 61e4560b733071cc8583158f7a171687 684 Gene3D G3DSA:3.50.50.60 409 523 6.5E-22 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_06420 61e4560b733071cc8583158f7a171687 684 Pfam PF01593 Flavin containing amine oxidoreductase 206 668 6.5E-22 T 14-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 TSH58p_06420 61e4560b733071cc8583158f7a171687 684 Gene3D G3DSA:3.50.50.60 197 301 1.3E-21 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_06420 61e4560b733071cc8583158f7a171687 684 SUPERFAMILY SSF51905 199 669 4.07E-55 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_19630 9020026774cebceb40da380dcbd5ee99 355 Pfam PF02653 Branched-chain amino acid transport system / permease component 54 316 7.2E-46 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_15830 6f7b0183b05e5a101ffefa1698dd5c45 513 SUPERFAMILY SSF103473 11 496 4.32E-69 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_15830 6f7b0183b05e5a101ffefa1698dd5c45 513 Pfam PF07690 Major Facilitator Superfamily 23 417 3.8E-49 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_15830 6f7b0183b05e5a101ffefa1698dd5c45 513 Gene3D G3DSA:1.20.1720.10 22 234 7.5E-56 T 14-10-2018 TSH58p_15830 6f7b0183b05e5a101ffefa1698dd5c45 513 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 18 428 1.7E-72 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 TSH58p_15830 6f7b0183b05e5a101ffefa1698dd5c45 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 308 332 2.1E-10 T 14-10-2018 TSH58p_15830 6f7b0183b05e5a101ffefa1698dd5c45 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 142 166 2.1E-10 T 14-10-2018 TSH58p_15830 6f7b0183b05e5a101ffefa1698dd5c45 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 408 427 2.1E-10 T 14-10-2018 TSH58p_15830 6f7b0183b05e5a101ffefa1698dd5c45 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 112 132 2.1E-10 T 14-10-2018 TSH58p_15830 6f7b0183b05e5a101ffefa1698dd5c45 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 22 46 2.1E-10 T 14-10-2018 TSH58p_20735 a7a0e59cab1a9f487d29798fecbf7e19 288 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 111 226 1.8E-31 T 14-10-2018 IPR031571 Flp pilus assembly protein RcpC/CpaB domain TSH58p_20735 a7a0e59cab1a9f487d29798fecbf7e19 288 SMART SM00858 39 105 4.5E-6 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 TSH58p_20735 a7a0e59cab1a9f487d29798fecbf7e19 288 Pfam PF08666 SAF domain 39 104 1.2E-8 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 TSH58p_20735 a7a0e59cab1a9f487d29798fecbf7e19 288 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 6 284 3.7E-60 T 14-10-2018 IPR017592 Pilus assembly, Flp-type CpaB TSH58p_02250 ac364840dfb36f0af9cd9de7af58ddea 379 Gene3D G3DSA:3.40.50.300 18 364 2.6E-92 T 14-10-2018 TSH58p_02250 ac364840dfb36f0af9cd9de7af58ddea 379 SMART SM00382 47 238 2.7E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_02250 ac364840dfb36f0af9cd9de7af58ddea 379 Pfam PF00005 ABC transporter 39 188 4.4E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_02250 ac364840dfb36f0af9cd9de7af58ddea 379 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 238 304 4.8E-17 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_02250 ac364840dfb36f0af9cd9de7af58ddea 379 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 240 303 6.3E-12 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_02250 ac364840dfb36f0af9cd9de7af58ddea 379 SUPERFAMILY SSF52540 28 259 2.25E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_02250 ac364840dfb36f0af9cd9de7af58ddea 379 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_32445 fd571717fb9b2eca8e4a1a5cc1dc43ef 404 Gene3D G3DSA:3.40.50.2300 151 282 1.3E-108 T 14-10-2018 TSH58p_32445 fd571717fb9b2eca8e4a1a5cc1dc43ef 404 Pfam PF13458 Periplasmic binding protein 32 368 2.0E-86 T 14-10-2018 IPR028081 Leucine-binding protein domain TSH58p_32445 fd571717fb9b2eca8e4a1a5cc1dc43ef 404 SUPERFAMILY SSF53822 32 403 5.23E-89 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_32445 fd571717fb9b2eca8e4a1a5cc1dc43ef 404 Gene3D G3DSA:3.40.50.2300 35 342 1.3E-108 T 14-10-2018 TSH58p_31585 43f38e80b28298b6b91f503e3b2a0411 356 Gene3D G3DSA:2.40.30.170 251 301 7.8E-16 T 14-10-2018 TSH58p_31585 43f38e80b28298b6b91f503e3b2a0411 356 Gene3D G3DSA:1.10.287.470 116 181 2.5E-5 T 14-10-2018 TSH58p_31585 43f38e80b28298b6b91f503e3b2a0411 356 SUPERFAMILY SSF111369 42 112 7.06E-8 T 14-10-2018 TSH58p_31585 43f38e80b28298b6b91f503e3b2a0411 356 Gene3D G3DSA:2.40.50.100 50 115 3.4E-11 T 14-10-2018 TSH58p_31585 43f38e80b28298b6b91f503e3b2a0411 356 Pfam PF13533 Biotin-lipoyl like 50 95 3.1E-11 T 14-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain TSH58p_31585 43f38e80b28298b6b91f503e3b2a0411 356 Gene3D G3DSA:1.10.287.470 184 215 7.8E-16 T 14-10-2018 TSH58p_31585 43f38e80b28298b6b91f503e3b2a0411 356 SUPERFAMILY SSF111369 174 288 2.88E-6 T 14-10-2018 TSH58p_31585 43f38e80b28298b6b91f503e3b2a0411 356 Gene3D G3DSA:2.40.50.100 216 250 7.8E-16 T 14-10-2018 TSH58p_31585 43f38e80b28298b6b91f503e3b2a0411 356 Pfam PF13437 HlyD family secretion protein 215 321 9.2E-14 T 14-10-2018 TSH58p_25210 5cf407445fcf3647919c928b8fc65eb3 567 SUPERFAMILY SSF58104 239 560 2.49E-59 T 14-10-2018 TSH58p_25210 5cf407445fcf3647919c928b8fc65eb3 567 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 188 1.3E-19 T 14-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain TSH58p_25210 5cf407445fcf3647919c928b8fc65eb3 567 Pfam PF00672 HAMP domain 219 266 1.1E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_25210 5cf407445fcf3647919c928b8fc65eb3 567 Gene3D G3DSA:1.10.287.950 274 566 7.7E-53 T 14-10-2018 TSH58p_25210 5cf407445fcf3647919c928b8fc65eb3 567 Gene3D G3DSA:1.20.1480.50 176 273 4.8E-12 T 14-10-2018 TSH58p_25210 5cf407445fcf3647919c928b8fc65eb3 567 SMART SM00304 217 270 4.8E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_25210 5cf407445fcf3647919c928b8fc65eb3 567 SMART SM00283 307 561 2.6E-40 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_25210 5cf407445fcf3647919c928b8fc65eb3 567 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 368 530 3.8E-32 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_25210 5cf407445fcf3647919c928b8fc65eb3 567 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 321 350 2.2E-5 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_25210 5cf407445fcf3647919c928b8fc65eb3 567 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 434 463 2.2E-5 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_28025 d11d87e8dce4e2ac45d86eebd460510c 304 SUPERFAMILY SSF52540 103 295 6.14E-33 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_28025 d11d87e8dce4e2ac45d86eebd460510c 304 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 115 276 5.5E-36 T 14-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain TSH58p_28025 d11d87e8dce4e2ac45d86eebd460510c 304 Gene3D G3DSA:3.40.50.300 95 302 6.0E-64 T 14-10-2018 TSH58p_28025 d11d87e8dce4e2ac45d86eebd460510c 304 PIRSF PIRSF005624 81 304 3.6E-95 T 14-10-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 TSH58p_28025 d11d87e8dce4e2ac45d86eebd460510c 304 TIGRFAM TIGR00073 hypB: hydrogenase accessory protein HypB 87 296 1.3E-88 T 14-10-2018 IPR004392 Hydrogenase maturation factor HypB GO:0016151|GO:0051604 TSH58p_28105 631772308b496f24b7bfc6dd410847da 569 TIGRFAM TIGR01178 ade: adenine deaminase 22 567 2.9E-177 T 14-10-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 TSH58p_28105 631772308b496f24b7bfc6dd410847da 569 SUPERFAMILY SSF51338 13 350 1.13E-14 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_28105 631772308b496f24b7bfc6dd410847da 569 SUPERFAMILY SSF51556 73 319 3.57E-30 T 14-10-2018 IPR032466 Metal-dependent hydrolase TSH58p_28105 631772308b496f24b7bfc6dd410847da 569 Gene3D G3DSA:2.30.40.10 15 350 2.8E-118 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_28105 631772308b496f24b7bfc6dd410847da 569 Gene3D G3DSA:3.20.20.140 73 314 2.8E-118 T 14-10-2018 TSH58p_28105 631772308b496f24b7bfc6dd410847da 569 Pfam PF01979 Amidohydrolase family 69 350 2.9E-23 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TSH58p_28105 631772308b496f24b7bfc6dd410847da 569 Pfam PF13382 Adenine deaminase C-terminal domain 398 564 1.7E-68 T 14-10-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 TSH58p_28105 631772308b496f24b7bfc6dd410847da 569 Hamap MF_01518 Adenine deaminase [ade]. 22 568 36.287 T 14-10-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 TSH58p_26055 1d37f3af9dae8d22e7e2f6dcdcdb3fe9 434 Gene3D G3DSA:3.40.50.1480 7 200 7.3E-100 T 14-10-2018 TSH58p_26055 1d37f3af9dae8d22e7e2f6dcdcdb3fe9 434 SMART SM00996 9 433 0.0 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TSH58p_26055 1d37f3af9dae8d22e7e2f6dcdcdb3fe9 434 Gene3D G3DSA:3.40.50.720 201 350 3.7E-76 T 14-10-2018 TSH58p_26055 1d37f3af9dae8d22e7e2f6dcdcdb3fe9 434 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 9 145 4.1E-74 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TSH58p_26055 1d37f3af9dae8d22e7e2f6dcdcdb3fe9 434 SUPERFAMILY SSF52283 7 434 1.98E-123 T 14-10-2018 TSH58p_26055 1d37f3af9dae8d22e7e2f6dcdcdb3fe9 434 SMART SM00997 195 354 4.5E-116 T 14-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TSH58p_26055 1d37f3af9dae8d22e7e2f6dcdcdb3fe9 434 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 217 234 - T 14-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TSH58p_26055 1d37f3af9dae8d22e7e2f6dcdcdb3fe9 434 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 10 426 1.0E-197 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TSH58p_26055 1d37f3af9dae8d22e7e2f6dcdcdb3fe9 434 SUPERFAMILY SSF51735 195 354 2.54E-79 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_26055 1d37f3af9dae8d22e7e2f6dcdcdb3fe9 434 PIRSF PIRSF001109 1 434 1.3E-202 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TSH58p_26055 1d37f3af9dae8d22e7e2f6dcdcdb3fe9 434 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 81 95 - T 14-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TSH58p_26055 1d37f3af9dae8d22e7e2f6dcdcdb3fe9 434 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 5 426 50.167 T 14-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 TSH58p_26055 1d37f3af9dae8d22e7e2f6dcdcdb3fe9 434 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 195 354 4.0E-83 T 14-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TSH58p_26055 1d37f3af9dae8d22e7e2f6dcdcdb3fe9 434 Gene3D G3DSA:3.40.50.1480 351 434 7.0E-42 T 14-10-2018 TSH58p_02120 71c6fdcc65824afe5a1ff508e62abc40 802 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 72 223 5.2E-8 T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TSH58p_02120 71c6fdcc65824afe5a1ff508e62abc40 802 PIRSF PIRSF000156 3 793 3.1E-61 T 14-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 TSH58p_02120 71c6fdcc65824afe5a1ff508e62abc40 802 SMART SM00861 413 632 9.9E-9 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSH58p_02120 71c6fdcc65824afe5a1ff508e62abc40 802 Gene3D G3DSA:3.40.50.970 401 640 4.8E-69 T 14-10-2018 TSH58p_02120 71c6fdcc65824afe5a1ff508e62abc40 802 Gene3D G3DSA:3.40.50.920 642 797 4.2E-17 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSH58p_02120 71c6fdcc65824afe5a1ff508e62abc40 802 SUPERFAMILY SSF52922 637 790 8.3E-28 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSH58p_02120 71c6fdcc65824afe5a1ff508e62abc40 802 SUPERFAMILY SSF52518 397 633 4.05E-56 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_02120 71c6fdcc65824afe5a1ff508e62abc40 802 SUPERFAMILY SSF52518 10 364 3.14E-78 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_02120 71c6fdcc65824afe5a1ff508e62abc40 802 Pfam PF02779 Transketolase, pyrimidine binding domain 413 597 1.7E-4 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSH58p_02120 71c6fdcc65824afe5a1ff508e62abc40 802 Gene3D G3DSA:3.40.50.970 2 383 5.9E-78 T 14-10-2018 TSH58p_28230 d7ead88b08e1db2ec01cb7d07a226faf 712 SMART SM00490 478 564 4.8E-19 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_28230 d7ead88b08e1db2ec01cb7d07a226faf 712 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 22 674 0.0 T 14-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 TSH58p_28230 d7ead88b08e1db2ec01cb7d07a226faf 712 Pfam PF02151 UvrB/uvrC motif 643 676 2.6E-7 T 14-10-2018 IPR001943 UVR domain GO:0005515 TSH58p_28230 d7ead88b08e1db2ec01cb7d07a226faf 712 SUPERFAMILY SSF52540 51 600 1.58E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_28230 d7ead88b08e1db2ec01cb7d07a226faf 712 Pfam PF04851 Type III restriction enzyme, res subunit 29 157 2.3E-11 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TSH58p_28230 d7ead88b08e1db2ec01cb7d07a226faf 712 SUPERFAMILY SSF46600 635 677 1.57E-10 T 14-10-2018 IPR036876 UVR domain superfamily TSH58p_28230 d7ead88b08e1db2ec01cb7d07a226faf 712 SMART SM00487 27 444 1.2E-27 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSH58p_28230 d7ead88b08e1db2ec01cb7d07a226faf 712 Pfam PF12344 Ultra-violet resistance protein B 570 611 8.0E-23 T 14-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain TSH58p_28230 d7ead88b08e1db2ec01cb7d07a226faf 712 Gene3D G3DSA:4.10.860.10 629 679 1.5E-6 T 14-10-2018 TSH58p_28230 d7ead88b08e1db2ec01cb7d07a226faf 712 Hamap MF_00204 UvrABC system protein B [uvrB]. 21 677 42.323 T 14-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 TSH58p_28230 d7ead88b08e1db2ec01cb7d07a226faf 712 SUPERFAMILY SSF52540 21 432 4.02E-133 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_28230 d7ead88b08e1db2ec01cb7d07a226faf 712 Pfam PF00271 Helicase conserved C-terminal domain 459 562 1.2E-17 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_28230 d7ead88b08e1db2ec01cb7d07a226faf 712 Gene3D G3DSA:3.40.50.300 293 432 9.3E-48 T 14-10-2018 TSH58p_28230 d7ead88b08e1db2ec01cb7d07a226faf 712 Gene3D G3DSA:3.40.50.300 15 254 1.5E-77 T 14-10-2018 TSH58p_28230 d7ead88b08e1db2ec01cb7d07a226faf 712 Gene3D G3DSA:3.40.50.300 433 614 8.6E-50 T 14-10-2018 TSH58p_30945 4ba339ea2e6a1cb2199b909663263bc3 351 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 53 294 2.6E-65 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 TSH58p_30945 4ba339ea2e6a1cb2199b909663263bc3 351 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 55 322 3.7E-69 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 TSH58p_30945 4ba339ea2e6a1cb2199b909663263bc3 351 PIRSF PIRSF006470 19 348 2.7E-71 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 TSH58p_30945 4ba339ea2e6a1cb2199b909663263bc3 351 Gene3D G3DSA:3.40.190.170 42 351 7.5E-104 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily TSH58p_03825 279d627d9837ea1b9361b636b8678855 260 Pfam PF00005 ABC transporter 39 175 3.1E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_03825 279d627d9837ea1b9361b636b8678855 260 Gene3D G3DSA:3.40.50.300 17 251 4.5E-63 T 14-10-2018 TSH58p_03825 279d627d9837ea1b9361b636b8678855 260 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_03825 279d627d9837ea1b9361b636b8678855 260 SUPERFAMILY SSF52540 20 234 1.33E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_03825 279d627d9837ea1b9361b636b8678855 260 SMART SM00382 46 225 5.5E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_00385 307de827019e678caaa6f63c920604df 523 Gene3D G3DSA:3.40.50.12780 27 411 4.9E-136 T 14-10-2018 TSH58p_00385 307de827019e678caaa6f63c920604df 523 SUPERFAMILY SSF56801 12 516 9.94E-146 T 14-10-2018 TSH58p_00385 307de827019e678caaa6f63c920604df 523 Pfam PF13193 AMP-binding enzyme C-terminal domain 427 503 3.2E-15 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSH58p_00385 307de827019e678caaa6f63c920604df 523 Gene3D G3DSA:3.30.300.310 414 519 1.4E-30 T 14-10-2018 TSH58p_00385 307de827019e678caaa6f63c920604df 523 ProSitePatterns PS00455 Putative AMP-binding domain signature. 174 185 - T 14-10-2018 IPR020845 AMP-binding, conserved site TSH58p_00385 307de827019e678caaa6f63c920604df 523 Pfam PF00501 AMP-binding enzyme 38 418 1.4E-102 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_26510 45dec4a55d008c2813b159851bc87db6 327 Gene3D G3DSA:3.30.200.20 27 100 2.6E-53 T 14-10-2018 TSH58p_26510 45dec4a55d008c2813b159851bc87db6 327 Gene3D G3DSA:3.30.470.20 101 240 2.6E-53 T 14-10-2018 TSH58p_26510 45dec4a55d008c2813b159851bc87db6 327 SUPERFAMILY SSF56104 17 303 3.27E-87 T 14-10-2018 TSH58p_26510 45dec4a55d008c2813b159851bc87db6 327 Pfam PF01259 SAICAR synthetase 26 277 4.7E-81 T 14-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSH58p_26510 45dec4a55d008c2813b159851bc87db6 327 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 23 300 22.496 T 14-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSH58p_26510 45dec4a55d008c2813b159851bc87db6 327 ProSitePatterns PS01058 SAICAR synthetase signature 2. 208 216 - T 14-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSH58p_16585 8b76c37cb47b91e07b828ee9f565faf1 394 PRINTS PR00103 cAMP-dependent protein kinase signature 261 275 7.0E-6 T 14-10-2018 TSH58p_16585 8b76c37cb47b91e07b828ee9f565faf1 394 PRINTS PR00103 cAMP-dependent protein kinase signature 317 328 7.0E-6 T 14-10-2018 TSH58p_16585 8b76c37cb47b91e07b828ee9f565faf1 394 PRINTS PR00103 cAMP-dependent protein kinase signature 305 314 7.0E-6 T 14-10-2018 TSH58p_16585 8b76c37cb47b91e07b828ee9f565faf1 394 Pfam PF00924 Mechanosensitive ion channel 9 207 4.2E-34 T 14-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 TSH58p_16585 8b76c37cb47b91e07b828ee9f565faf1 394 SUPERFAMILY SSF50182 50 117 2.71E-16 T 14-10-2018 IPR010920 LSM domain superfamily TSH58p_16585 8b76c37cb47b91e07b828ee9f565faf1 394 SUPERFAMILY SSF51206 233 364 1.7E-31 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like TSH58p_16585 8b76c37cb47b91e07b828ee9f565faf1 394 SMART SM00100 240 357 1.0E-24 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_16585 8b76c37cb47b91e07b828ee9f565faf1 394 Gene3D G3DSA:3.30.70.100 121 212 2.4E-7 T 14-10-2018 TSH58p_16585 8b76c37cb47b91e07b828ee9f565faf1 394 Pfam PF00027 Cyclic nucleotide-binding domain 259 344 2.1E-21 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_16585 8b76c37cb47b91e07b828ee9f565faf1 394 Gene3D G3DSA:2.60.120.10 231 371 2.6E-36 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_16585 8b76c37cb47b91e07b828ee9f565faf1 394 SUPERFAMILY SSF82689 124 216 4.32E-11 T 14-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 TSH58p_16585 8b76c37cb47b91e07b828ee9f565faf1 394 Gene3D G3DSA:2.30.30.60 66 116 4.7E-13 T 14-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily TSH58p_16585 8b76c37cb47b91e07b828ee9f565faf1 394 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 307 324 - T 14-10-2018 IPR018488 Cyclic nucleotide-binding, conserved site TSH58p_31845 d63c1ae9a36be313eaadcf9d32c54030 459 Gene3D G3DSA:2.40.160.60 22 447 1.1E-92 T 14-10-2018 TSH58p_31845 d63c1ae9a36be313eaadcf9d32c54030 459 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 13 443 3.7E-51 T 14-10-2018 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) TSH58p_31845 d63c1ae9a36be313eaadcf9d32c54030 459 SUPERFAMILY SSF56935 25 432 1.32E-50 T 14-10-2018 TSH58p_14140 15c3edbadbfed8ae19aad763b8ca1524 465 Pfam PF01575 MaoC like domain 15 114 4.5E-19 T 14-10-2018 IPR002539 MaoC-like dehydratase domain TSH58p_14140 15c3edbadbfed8ae19aad763b8ca1524 465 SUPERFAMILY SSF53659 171 453 5.35E-72 T 14-10-2018 TSH58p_14140 15c3edbadbfed8ae19aad763b8ca1524 465 Pfam PF01515 Phosphate acetyl/butaryl transferase 237 449 2.3E-47 T 14-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 TSH58p_14140 15c3edbadbfed8ae19aad763b8ca1524 465 SUPERFAMILY SSF54637 4 142 4.23E-40 T 14-10-2018 IPR029069 HotDog domain superfamily TSH58p_14140 15c3edbadbfed8ae19aad763b8ca1524 465 Gene3D G3DSA:3.10.129.10 1 155 1.1E-46 T 14-10-2018 TSH58p_14140 15c3edbadbfed8ae19aad763b8ca1524 465 Gene3D G3DSA:3.40.718.10 161 454 8.0E-99 T 14-10-2018 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 15 827 2.8E-293 T 14-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 SMART SM00387 41 196 3.6E-26 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 Pfam PF01751 Toprim domain 446 557 5.3E-18 T 14-10-2018 IPR006171 TOPRIM domain TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 PRINTS PR00418 DNA topoisomerase II family signature 447 461 2.0E-70 T 14-10-2018 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 PRINTS PR00418 DNA topoisomerase II family signature 514 530 2.0E-70 T 14-10-2018 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 PRINTS PR00418 DNA topoisomerase II family signature 759 775 2.0E-70 T 14-10-2018 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 PRINTS PR00418 DNA topoisomerase II family signature 295 308 2.0E-70 T 14-10-2018 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 PRINTS PR00418 DNA topoisomerase II family signature 45 60 2.0E-70 T 14-10-2018 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 PRINTS PR00418 DNA topoisomerase II family signature 80 93 2.0E-70 T 14-10-2018 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 PRINTS PR00418 DNA topoisomerase II family signature 532 549 2.0E-70 T 14-10-2018 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 PRINTS PR00418 DNA topoisomerase II family signature 123 137 2.0E-70 T 14-10-2018 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 PRINTS PR00418 DNA topoisomerase II family signature 552 564 2.0E-70 T 14-10-2018 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 Gene3D G3DSA:3.30.565.10 12 242 3.6E-84 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 Gene3D G3DSA:3.40.50.670 425 596 8.2E-72 T 14-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 Pfam PF00204 DNA gyrase B 243 417 2.3E-57 T 14-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 12 827 98.532 T 14-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 SMART SM00433 45 820 1.8E-253 T 14-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 SUPERFAMILY SSF54211 243 418 8.91E-54 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 Gene3D G3DSA:3.40.50.670 722 826 5.9E-24 T 14-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 PRINTS PR01159 DNA gyrase subunit B signature 269 287 2.6E-69 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 PRINTS PR01159 DNA gyrase subunit B signature 216 229 2.6E-69 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 PRINTS PR01159 DNA gyrase subunit B signature 242 264 2.6E-69 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 PRINTS PR01159 DNA gyrase subunit B signature 15 25 2.6E-69 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 PRINTS PR01159 DNA gyrase subunit B signature 201 216 2.6E-69 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 PRINTS PR01159 DNA gyrase subunit B signature 796 812 2.6E-69 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 PRINTS PR01159 DNA gyrase subunit B signature 339 355 2.6E-69 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 PRINTS PR01159 DNA gyrase subunit B signature 387 401 2.6E-69 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 PRINTS PR01159 DNA gyrase subunit B signature 780 792 2.6E-69 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 PRINTS PR01159 DNA gyrase subunit B signature 497 506 2.6E-69 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 PRINTS PR01159 DNA gyrase subunit B signature 401 421 2.6E-69 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 SUPERFAMILY SSF55874 15 229 4.98E-65 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 755 816 3.3E-29 T 14-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 ProSitePatterns PS00177 DNA topoisomerase II signature. 449 457 - T 14-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 SUPERFAMILY SSF56719 421 818 4.71E-85 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 42 192 3.5E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_26970 da642e81f555bbbe113bce40e929926f 827 Gene3D G3DSA:3.30.230.10 243 419 1.4E-68 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSH58p_18180 dbe68bc77699b949be2d5a27d8411dbd 118 Pfam PF05717 IS66 Orf2 like protein 10 107 6.3E-36 T 14-10-2018 IPR008878 Transposase IS66, Orf2 TSH58p_01085 21ec8a3c4f421d8b3f3144bfbfb85e27 627 SUPERFAMILY SSF50998 31 572 2.09E-170 T 14-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TSH58p_01085 21ec8a3c4f421d8b3f3144bfbfb85e27 627 TIGRFAM TIGR03075 PQQ_enz_alc_DH: PQQ-dependent dehydrogenase, methanol/ethanol family 19 561 1.8E-224 T 14-10-2018 IPR017512 PQQ-dependent dehydrogenase, methanol/ethanol family GO:0005509|GO:0016020|GO:0016614|GO:0055114 TSH58p_01085 21ec8a3c4f421d8b3f3144bfbfb85e27 627 ProSitePatterns PS00364 Bacterial quinoprotein dehydrogenases signature 2. 260 281 - T 14-10-2018 IPR001479 Quinoprotein dehydrogenase, conserved site GO:0030288|GO:0055114 TSH58p_01085 21ec8a3c4f421d8b3f3144bfbfb85e27 627 Pfam PF01011 PQQ enzyme repeat 507 539 2.6E-8 T 14-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat TSH58p_01085 21ec8a3c4f421d8b3f3144bfbfb85e27 627 Gene3D G3DSA:2.140.10.10 23 627 3.3E-214 T 14-10-2018 TSH58p_01085 21ec8a3c4f421d8b3f3144bfbfb85e27 627 Pfam PF13360 PQQ-like domain 297 490 2.3E-4 T 14-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat TSH58p_01085 21ec8a3c4f421d8b3f3144bfbfb85e27 627 Pfam PF13360 PQQ-like domain 106 220 3.8E-13 T 14-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat TSH58p_01085 21ec8a3c4f421d8b3f3144bfbfb85e27 627 SMART SM00564 132 164 9.4E-6 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSH58p_01085 21ec8a3c4f421d8b3f3144bfbfb85e27 627 SMART SM00564 448 492 130.0 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSH58p_01085 21ec8a3c4f421d8b3f3144bfbfb85e27 627 SMART SM00564 501 533 4.7E-6 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSH58p_01085 21ec8a3c4f421d8b3f3144bfbfb85e27 627 SMART SM00564 178 215 0.003 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSH58p_01085 21ec8a3c4f421d8b3f3144bfbfb85e27 627 SMART SM00564 264 319 52.0 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSH58p_01085 21ec8a3c4f421d8b3f3144bfbfb85e27 627 SMART SM00564 80 113 70.0 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSH58p_13715 a9eeaf9636389e45ae1b2ba704f4ee97 205 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 20 203 6.4E-34 T 14-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 TSH58p_13715 a9eeaf9636389e45ae1b2ba704f4ee97 205 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 16 204 20.23 T 14-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 TSH58p_13715 a9eeaf9636389e45ae1b2ba704f4ee97 205 Pfam PF01467 Cytidylyltransferase-like 20 200 2.1E-18 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TSH58p_13715 a9eeaf9636389e45ae1b2ba704f4ee97 205 Gene3D G3DSA:3.40.50.620 15 205 1.9E-39 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_13715 a9eeaf9636389e45ae1b2ba704f4ee97 205 SUPERFAMILY SSF52374 16 204 4.38E-37 T 14-10-2018 TSH58p_06080 05de3b7e470120d529b4c0a1397352ee 297 Gene3D G3DSA:3.40.50.2020 151 287 3.8E-23 T 14-10-2018 TSH58p_06080 05de3b7e470120d529b4c0a1397352ee 297 SUPERFAMILY SSF53271 85 273 1.97E-26 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like TSH58p_06080 05de3b7e470120d529b4c0a1397352ee 297 Pfam PF00156 Phosphoribosyl transferase domain 149 248 1.7E-12 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TSH58p_06080 05de3b7e470120d529b4c0a1397352ee 297 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 17 114 7.5E-15 T 14-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TSH58p_06080 05de3b7e470120d529b4c0a1397352ee 297 Gene3D G3DSA:3.40.50.2020 7 150 1.5E-33 T 14-10-2018 TSH58p_06080 05de3b7e470120d529b4c0a1397352ee 297 SUPERFAMILY SSF53271 11 157 1.76E-28 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like TSH58p_06080 05de3b7e470120d529b4c0a1397352ee 297 SMART SM01400 5 118 1.2E-23 T 14-10-2018 TSH58p_06080 05de3b7e470120d529b4c0a1397352ee 297 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 14 294 3.9E-46 T 14-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TSH58p_31165 f5a00565c3b44bd650fbd493a4843b8b 466 SUPERFAMILY SSF75011 55 403 2.09E-21 T 14-10-2018 TSH58p_31165 f5a00565c3b44bd650fbd493a4843b8b 466 Pfam PF05694 56kDa selenium binding protein (SBP56) 5 464 5.2E-201 T 14-10-2018 IPR008826 Selenium-binding protein GO:0008430 TSH58p_26265 17821de4e0ae0d2ff66b6a557cc9e168 157 SUPERFAMILY SSF53850 12 143 9.93E-24 T 14-10-2018 TSH58p_26265 17821de4e0ae0d2ff66b6a557cc9e168 157 Pfam PF03466 LysR substrate binding domain 20 142 1.1E-24 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_26265 17821de4e0ae0d2ff66b6a557cc9e168 157 Gene3D G3DSA:3.40.190.10 25 113 2.5E-29 T 14-10-2018 TSH58p_26265 17821de4e0ae0d2ff66b6a557cc9e168 157 Gene3D G3DSA:3.40.190.10 114 139 2.5E-29 T 14-10-2018 TSH58p_09530 34e2d134550c57d90499d72826909d21 419 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 11 386 8.5E-103 T 14-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 TSH58p_09530 34e2d134550c57d90499d72826909d21 419 SMART SM00729 136 355 3.6E-53 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSH58p_09530 34e2d134550c57d90499d72826909d21 419 Gene3D G3DSA:3.80.30.20 133 367 1.2E-70 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TSH58p_09530 34e2d134550c57d90499d72826909d21 419 Gene3D G3DSA:3.40.50.12160 9 120 7.8E-18 T 14-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily TSH58p_09530 34e2d134550c57d90499d72826909d21 419 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 11 388 7.4E-130 T 14-10-2018 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 TSH58p_09530 34e2d134550c57d90499d72826909d21 419 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 140 160 - T 14-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 TSH58p_09530 34e2d134550c57d90499d72826909d21 419 Pfam PF00919 Uncharacterized protein family UPF0004 11 95 2.1E-17 T 14-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 TSH58p_09530 34e2d134550c57d90499d72826909d21 419 Pfam PF04055 Radical SAM superfamily 141 313 3.3E-23 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSH58p_09530 34e2d134550c57d90499d72826909d21 419 SUPERFAMILY SSF102114 115 358 9.81E-56 T 14-10-2018 TSH58p_09730 750cc0940c0a7a7078a6f8b1010fe90a 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 285 6.5E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_09730 750cc0940c0a7a7078a6f8b1010fe90a 290 SUPERFAMILY SSF161098 13 286 3.46E-60 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_09730 750cc0940c0a7a7078a6f8b1010fe90a 290 Gene3D G3DSA:1.10.3720.10 8 283 1.1E-55 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_19335 55f419d889a163d0b3c39e4bb360fb3f 401 Pfam PF02515 CoA-transferase family III 5 376 2.0E-62 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 TSH58p_19335 55f419d889a163d0b3c39e4bb360fb3f 401 SUPERFAMILY SSF89796 2 400 1.02E-80 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily TSH58p_19335 55f419d889a163d0b3c39e4bb360fb3f 401 Gene3D G3DSA:3.40.50.10540 5 394 2.6E-71 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily TSH58p_19335 55f419d889a163d0b3c39e4bb360fb3f 401 Gene3D G3DSA:3.30.1540.10 227 324 2.6E-71 T 14-10-2018 TSH58p_31760 b410535df28d9c609a1f1b2d54effe18 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 61 82 1.1E-6 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSH58p_31760 b410535df28d9c609a1f1b2d54effe18 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 159 173 1.1E-6 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSH58p_31760 b410535df28d9c609a1f1b2d54effe18 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 257 276 1.1E-6 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSH58p_31760 b410535df28d9c609a1f1b2d54effe18 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 105 118 1.1E-6 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSH58p_31760 b410535df28d9c609a1f1b2d54effe18 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 45 61 1.1E-6 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSH58p_31760 b410535df28d9c609a1f1b2d54effe18 356 Gene3D G3DSA:3.40.190.10 43 319 4.4E-81 T 14-10-2018 TSH58p_31760 b410535df28d9c609a1f1b2d54effe18 356 SUPERFAMILY SSF53850 36 353 1.9E-56 T 14-10-2018 TSH58p_31760 b410535df28d9c609a1f1b2d54effe18 356 Pfam PF13416 Bacterial extracellular solute-binding protein 55 317 1.5E-27 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSH58p_31760 b410535df28d9c609a1f1b2d54effe18 356 Gene3D G3DSA:3.40.190.10 144 335 4.4E-81 T 14-10-2018 TSH58p_11175 f2492839f39ab8c07e2997f769226bd7 513 SMART SM00388 280 349 4.6E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_11175 f2492839f39ab8c07e2997f769226bd7 513 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 16 139 1.7E-23 T 14-10-2018 IPR000014 PAS domain TSH58p_11175 f2492839f39ab8c07e2997f769226bd7 513 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 141 267 8.6E-25 T 14-10-2018 IPR000014 PAS domain TSH58p_11175 f2492839f39ab8c07e2997f769226bd7 513 Gene3D G3DSA:3.30.450.20 145 258 1.2E-29 T 14-10-2018 TSH58p_11175 f2492839f39ab8c07e2997f769226bd7 513 SUPERFAMILY SSF55785 129 257 1.31E-26 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_11175 f2492839f39ab8c07e2997f769226bd7 513 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 396 507 8.9E-25 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_11175 f2492839f39ab8c07e2997f769226bd7 513 SUPERFAMILY SSF47384 265 350 2.16E-18 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_11175 f2492839f39ab8c07e2997f769226bd7 513 SUPERFAMILY SSF55785 17 130 3.67E-23 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_11175 f2492839f39ab8c07e2997f769226bd7 513 Gene3D G3DSA:3.30.565.10 348 508 1.5E-45 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_11175 f2492839f39ab8c07e2997f769226bd7 513 Gene3D G3DSA:3.30.450.20 14 144 1.2E-23 T 14-10-2018 TSH58p_11175 f2492839f39ab8c07e2997f769226bd7 513 Gene3D G3DSA:1.10.287.130 259 347 1.4E-22 T 14-10-2018 TSH58p_11175 f2492839f39ab8c07e2997f769226bd7 513 PRINTS PR00344 Bacterial sensor protein C-terminal signature 492 505 4.2E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_11175 f2492839f39ab8c07e2997f769226bd7 513 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 447 4.2E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_11175 f2492839f39ab8c07e2997f769226bd7 513 PRINTS PR00344 Bacterial sensor protein C-terminal signature 451 461 4.2E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_11175 f2492839f39ab8c07e2997f769226bd7 513 PRINTS PR00344 Bacterial sensor protein C-terminal signature 468 486 4.2E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_11175 f2492839f39ab8c07e2997f769226bd7 513 SUPERFAMILY SSF55874 338 506 4.19E-45 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_11175 f2492839f39ab8c07e2997f769226bd7 513 Pfam PF00512 His Kinase A (phospho-acceptor) domain 281 349 3.0E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_11175 f2492839f39ab8c07e2997f769226bd7 513 Pfam PF00989 PAS fold 18 129 1.3E-14 T 14-10-2018 IPR013767 PAS fold GO:0006355 TSH58p_11175 f2492839f39ab8c07e2997f769226bd7 513 Pfam PF00989 PAS fold 145 243 2.6E-11 T 14-10-2018 IPR013767 PAS fold GO:0006355 TSH58p_11175 f2492839f39ab8c07e2997f769226bd7 513 SMART SM00091 17 83 3.8E-12 T 14-10-2018 IPR000014 PAS domain TSH58p_11175 f2492839f39ab8c07e2997f769226bd7 513 SMART SM00091 144 210 5.3E-13 T 14-10-2018 IPR000014 PAS domain TSH58p_11175 f2492839f39ab8c07e2997f769226bd7 513 SMART SM00387 395 508 2.6E-37 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_06115 7c9a309af4a1a402739dc43aae4b04a2 358 SUPERFAMILY SSF53822 168 237 4.32E-6 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_06115 7c9a309af4a1a402739dc43aae4b04a2 358 Gene3D G3DSA:3.40.50.2300 132 348 1.8E-137 T 14-10-2018 TSH58p_06115 7c9a309af4a1a402739dc43aae4b04a2 358 Gene3D G3DSA:3.40.50.2300 29 285 1.8E-137 T 14-10-2018 TSH58p_06115 7c9a309af4a1a402739dc43aae4b04a2 358 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 28 289 1.9E-48 T 14-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 TSH58p_24455 d2ae86d27950731092d9c5dbff62f589 232 Pfam PF02678 Pirin 9 119 1.6E-35 T 14-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 TSH58p_24455 d2ae86d27950731092d9c5dbff62f589 232 SUPERFAMILY SSF51182 1 231 6.68E-78 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_24455 d2ae86d27950731092d9c5dbff62f589 232 Gene3D G3DSA:2.60.120.10 133 232 2.1E-37 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_24455 d2ae86d27950731092d9c5dbff62f589 232 Gene3D G3DSA:2.60.120.10 12 132 5.4E-56 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_24455 d2ae86d27950731092d9c5dbff62f589 232 PIRSF PIRSF006232 1 230 8.1E-56 T 14-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 TSH58p_01385 215ca7db29921c9d5446d5392598de6a 598 SMART SM00382 365 565 3.8E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_01385 215ca7db29921c9d5446d5392598de6a 598 Gene3D G3DSA:3.40.50.300 336 588 7.2E-57 T 14-10-2018 TSH58p_01385 215ca7db29921c9d5446d5392598de6a 598 Pfam PF02653 Branched-chain amino acid transport system / permease component 37 298 7.2E-32 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_01385 215ca7db29921c9d5446d5392598de6a 598 SUPERFAMILY SSF52540 339 588 1.15E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_01385 215ca7db29921c9d5446d5392598de6a 598 Pfam PF00005 ABC transporter 356 516 5.7E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_10635 cd4c0f79193f214c94f754892256716e 168 PRINTS PR00070 Dihydrofolate reductase signature 41 52 4.7E-15 T 14-10-2018 TSH58p_10635 cd4c0f79193f214c94f754892256716e 168 PRINTS PR00070 Dihydrofolate reductase signature 28 36 4.7E-15 T 14-10-2018 TSH58p_10635 cd4c0f79193f214c94f754892256716e 168 PRINTS PR00070 Dihydrofolate reductase signature 14 24 4.7E-15 T 14-10-2018 TSH58p_10635 cd4c0f79193f214c94f754892256716e 168 PRINTS PR00070 Dihydrofolate reductase signature 96 110 4.7E-15 T 14-10-2018 TSH58p_10635 cd4c0f79193f214c94f754892256716e 168 SUPERFAMILY SSF53597 1 162 3.93E-52 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TSH58p_10635 cd4c0f79193f214c94f754892256716e 168 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 14 36 - T 14-10-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 TSH58p_10635 cd4c0f79193f214c94f754892256716e 168 Gene3D G3DSA:3.40.430.10 1 166 1.6E-50 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TSH58p_10635 cd4c0f79193f214c94f754892256716e 168 PIRSF PIRSF000194 1 164 3.7E-54 T 14-10-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0046654|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614 TSH58p_10635 cd4c0f79193f214c94f754892256716e 168 Pfam PF00186 Dihydrofolate reductase 3 160 7.7E-48 T 14-10-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 TSH58p_12195 8b03209ca8893823e2302b3fbededdfb 157 SUPERFAMILY SSF52788 1 152 3.14E-52 T 14-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily TSH58p_12195 8b03209ca8893823e2302b3fbededdfb 157 Gene3D G3DSA:3.40.50.2300 1 156 2.0E-60 T 14-10-2018 TSH58p_12195 8b03209ca8893823e2302b3fbededdfb 157 SMART SM00226 2 151 1.6E-60 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I TSH58p_12195 8b03209ca8893823e2302b3fbededdfb 157 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 148 1.0E-42 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I TSH58p_12195 8b03209ca8893823e2302b3fbededdfb 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 47 63 4.0E-26 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 TSH58p_12195 8b03209ca8893823e2302b3fbededdfb 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 104 117 4.0E-26 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 TSH58p_12195 8b03209ca8893823e2302b3fbededdfb 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 81 96 4.0E-26 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 TSH58p_12195 8b03209ca8893823e2302b3fbededdfb 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 4.0E-26 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 TSH58p_12195 8b03209ca8893823e2302b3fbededdfb 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 123 138 4.0E-26 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 TSH58p_08895 a8e3c17fbc289da91bde26e5de8b041a 131 SUPERFAMILY SSF46626 29 129 1.2E-33 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_08895 a8e3c17fbc289da91bde26e5de8b041a 131 Pfam PF00034 Cytochrome c 33 129 3.8E-10 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_08895 a8e3c17fbc289da91bde26e5de8b041a 131 PRINTS PR00604 Class IA and IB cytochrome C signature 84 100 1.1E-20 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_08895 a8e3c17fbc289da91bde26e5de8b041a 131 PRINTS PR00604 Class IA and IB cytochrome C signature 53 68 1.1E-20 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_08895 a8e3c17fbc289da91bde26e5de8b041a 131 PRINTS PR00604 Class IA and IB cytochrome C signature 120 128 1.1E-20 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_08895 a8e3c17fbc289da91bde26e5de8b041a 131 PRINTS PR00604 Class IA and IB cytochrome C signature 103 113 1.1E-20 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_08895 a8e3c17fbc289da91bde26e5de8b041a 131 PRINTS PR00604 Class IA and IB cytochrome C signature 41 48 1.1E-20 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_08895 a8e3c17fbc289da91bde26e5de8b041a 131 Gene3D G3DSA:1.10.760.10 3 129 3.1E-42 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_28830 d68fe05ce5ff6a59a5cdb1524083160b 526 Gene3D G3DSA:3.40.30.80 1 199 4.9E-64 T 14-10-2018 TSH58p_28830 d68fe05ce5ff6a59a5cdb1524083160b 526 SUPERFAMILY SSF52833 104 196 8.0E-22 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_28830 d68fe05ce5ff6a59a5cdb1524083160b 526 Pfam PF13192 Thioredoxin domain 124 194 1.4E-6 T 14-10-2018 IPR012336 Thioredoxin-like fold TSH58p_28830 d68fe05ce5ff6a59a5cdb1524083160b 526 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 212 503 9.4E-46 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSH58p_28830 d68fe05ce5ff6a59a5cdb1524083160b 526 SUPERFAMILY SSF51905 205 514 1.83E-53 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_28830 d68fe05ce5ff6a59a5cdb1524083160b 526 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 1 516 8.3E-245 T 14-10-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0050660|GO:0051287 TSH58p_28830 d68fe05ce5ff6a59a5cdb1524083160b 526 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 467 489 1.9E-40 T 14-10-2018 TSH58p_28830 d68fe05ce5ff6a59a5cdb1524083160b 526 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 214 233 1.9E-40 T 14-10-2018 TSH58p_28830 d68fe05ce5ff6a59a5cdb1524083160b 526 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 356 374 1.9E-40 T 14-10-2018 TSH58p_28830 d68fe05ce5ff6a59a5cdb1524083160b 526 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 314 332 1.9E-40 T 14-10-2018 TSH58p_28830 d68fe05ce5ff6a59a5cdb1524083160b 526 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 441 457 1.9E-40 T 14-10-2018 TSH58p_28830 d68fe05ce5ff6a59a5cdb1524083160b 526 Gene3D G3DSA:3.50.50.60 212 507 1.2E-112 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_28830 d68fe05ce5ff6a59a5cdb1524083160b 526 SUPERFAMILY SSF52833 2 100 6.64E-31 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_28830 d68fe05ce5ff6a59a5cdb1524083160b 526 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 344 364 - T 14-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 TSH58p_28830 d68fe05ce5ff6a59a5cdb1524083160b 526 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 213 235 8.5E-65 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_28830 d68fe05ce5ff6a59a5cdb1524083160b 526 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 404 420 8.5E-65 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_28830 d68fe05ce5ff6a59a5cdb1524083160b 526 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 245 260 8.5E-65 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_28830 d68fe05ce5ff6a59a5cdb1524083160b 526 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 352 376 8.5E-65 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_28830 d68fe05ce5ff6a59a5cdb1524083160b 526 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 477 495 8.5E-65 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_28830 d68fe05ce5ff6a59a5cdb1524083160b 526 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 265 275 8.5E-65 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_28830 d68fe05ce5ff6a59a5cdb1524083160b 526 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 443 464 8.5E-65 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_28830 d68fe05ce5ff6a59a5cdb1524083160b 526 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 337 349 8.5E-65 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_28830 d68fe05ce5ff6a59a5cdb1524083160b 526 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 315 323 8.5E-65 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_28830 d68fe05ce5ff6a59a5cdb1524083160b 526 PIRSF PIRSF000238 1 520 1.7E-267 T 14-10-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0050660|GO:0051287 TSH58p_28830 d68fe05ce5ff6a59a5cdb1524083160b 526 Gene3D G3DSA:3.50.50.60 326 449 1.2E-112 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_09085 f0c955cf1b1053dd865d37f2a52131a0 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 263 6.6E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_09085 f0c955cf1b1053dd865d37f2a52131a0 270 Gene3D G3DSA:1.10.3720.10 70 265 3.1E-22 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_09085 f0c955cf1b1053dd865d37f2a52131a0 270 SUPERFAMILY SSF161098 69 264 2.62E-30 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_23605 647654db8153108776d661d0ad778dfd 504 Gene3D G3DSA:3.90.700.10 274 436 8.6E-103 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_23605 647654db8153108776d661d0ad778dfd 504 Gene3D G3DSA:3.50.50.60 20 493 8.6E-103 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_23605 647654db8153108776d661d0ad778dfd 504 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 21 40 2.5E-5 T 14-10-2018 TSH58p_23605 647654db8153108776d661d0ad778dfd 504 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 2.5E-5 T 14-10-2018 TSH58p_23605 647654db8153108776d661d0ad778dfd 504 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 215 231 2.5E-5 T 14-10-2018 TSH58p_23605 647654db8153108776d661d0ad778dfd 504 SUPERFAMILY SSF51905 19 499 8.55E-40 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_23605 647654db8153108776d661d0ad778dfd 504 Pfam PF00890 FAD binding domain 20 476 9.5E-48 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_23605 647654db8153108776d661d0ad778dfd 504 SUPERFAMILY SSF56425 292 440 1.0E-23 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_08610 a0dffc7d0248a36bc7145470e4dcb10b 537 Pfam PF13742 OB-fold nucleic acid binding domain 19 112 1.8E-27 T 14-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 TSH58p_08610 a0dffc7d0248a36bc7145470e4dcb10b 537 Pfam PF02601 Exonuclease VII, large subunit 135 495 4.9E-91 T 14-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 TSH58p_08610 a0dffc7d0248a36bc7145470e4dcb10b 537 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 20 362 8.4E-119 T 14-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 TSH58p_08610 a0dffc7d0248a36bc7145470e4dcb10b 537 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 16 498 27.183 T 14-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 TSH58p_19125 5a3fcd0ae9617306ee7c5a62952daa42 465 PRINTS PR01005 Flagellar hook-associated protein signature 122 142 8.2E-8 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 TSH58p_19125 5a3fcd0ae9617306ee7c5a62952daa42 465 PRINTS PR01005 Flagellar hook-associated protein signature 13 36 8.2E-8 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 TSH58p_19125 5a3fcd0ae9617306ee7c5a62952daa42 465 PRINTS PR01005 Flagellar hook-associated protein signature 155 179 8.2E-8 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 TSH58p_19125 5a3fcd0ae9617306ee7c5a62952daa42 465 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 7 463 2.8E-79 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 TSH58p_19125 5a3fcd0ae9617306ee7c5a62952daa42 465 SUPERFAMILY SSF64518 164 462 8.63E-7 T 14-10-2018 TSH58p_19125 5a3fcd0ae9617306ee7c5a62952daa42 465 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 396 463 1.1E-7 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain TSH58p_13385 1123a5ccba1693d389dcd7aca1c09f19 192 SUPERFAMILY SSF52799 52 153 1.09E-13 T 14-10-2018 IPR029021 Protein-tyrosine phosphatase-like TSH58p_13385 1123a5ccba1693d389dcd7aca1c09f19 192 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 96 106 - T 14-10-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 TSH58p_13385 1123a5ccba1693d389dcd7aca1c09f19 192 Gene3D G3DSA:3.90.190.10 11 162 5.8E-12 T 14-10-2018 IPR029021 Protein-tyrosine phosphatase-like TSH58p_27235 6ba405b1ea3ee3e74db2d237d40bbe1f 176 SUPERFAMILY SSF52540 1 165 1.8E-22 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_27235 6ba405b1ea3ee3e74db2d237d40bbe1f 176 Gene3D G3DSA:3.40.50.300 1 165 3.9E-33 T 14-10-2018 TSH58p_27235 6ba405b1ea3ee3e74db2d237d40bbe1f 176 Pfam PF13671 AAA domain 2 118 6.6E-14 T 14-10-2018 TSH58p_15850 9948d955687abbc7cff3549f626c2ca9 848 Gene3D G3DSA:3.40.50.2300 713 847 6.7E-26 T 14-10-2018 TSH58p_15850 9948d955687abbc7cff3549f626c2ca9 848 SMART SM00091 201 267 4.7E-10 T 14-10-2018 IPR000014 PAS domain TSH58p_15850 9948d955687abbc7cff3549f626c2ca9 848 SMART SM00091 65 131 2.6E-4 T 14-10-2018 IPR000014 PAS domain TSH58p_15850 9948d955687abbc7cff3549f626c2ca9 848 SMART SM00091 327 394 2.0 T 14-10-2018 IPR000014 PAS domain TSH58p_15850 9948d955687abbc7cff3549f626c2ca9 848 SUPERFAMILY SSF55785 312 461 1.8E-10 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_15850 9948d955687abbc7cff3549f626c2ca9 848 SUPERFAMILY SSF55785 186 313 4.19E-20 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_15850 9948d955687abbc7cff3549f626c2ca9 848 Gene3D G3DSA:3.30.450.20 50 180 1.3E-10 T 14-10-2018 TSH58p_15850 9948d955687abbc7cff3549f626c2ca9 848 PRINTS PR00344 Bacterial sensor protein C-terminal signature 639 649 6.5E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_15850 9948d955687abbc7cff3549f626c2ca9 848 PRINTS PR00344 Bacterial sensor protein C-terminal signature 680 693 6.5E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_15850 9948d955687abbc7cff3549f626c2ca9 848 PRINTS PR00344 Bacterial sensor protein C-terminal signature 656 674 6.5E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_15850 9948d955687abbc7cff3549f626c2ca9 848 PRINTS PR00344 Bacterial sensor protein C-terminal signature 621 635 6.5E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_15850 9948d955687abbc7cff3549f626c2ca9 848 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 199 322 1.1E-17 T 14-10-2018 IPR000014 PAS domain TSH58p_15850 9948d955687abbc7cff3549f626c2ca9 848 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 63 142 1.3E-5 T 14-10-2018 IPR000014 PAS domain TSH58p_15850 9948d955687abbc7cff3549f626c2ca9 848 Gene3D G3DSA:3.30.450.20 326 469 3.7E-12 T 14-10-2018 TSH58p_15850 9948d955687abbc7cff3549f626c2ca9 848 Gene3D G3DSA:3.30.565.10 541 696 3.0E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_15850 9948d955687abbc7cff3549f626c2ca9 848 SUPERFAMILY SSF47384 463 541 2.55E-11 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_15850 9948d955687abbc7cff3549f626c2ca9 848 Gene3D G3DSA:1.10.287.130 470 540 1.1E-6 T 14-10-2018 TSH58p_15850 9948d955687abbc7cff3549f626c2ca9 848 SMART SM00387 585 696 5.1E-35 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_15850 9948d955687abbc7cff3549f626c2ca9 848 Gene3D G3DSA:3.30.450.20 198 325 2.2E-27 T 14-10-2018 TSH58p_15850 9948d955687abbc7cff3549f626c2ca9 848 SMART SM00448 721 834 4.7E-19 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_15850 9948d955687abbc7cff3549f626c2ca9 848 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 586 694 7.6E-25 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_15850 9948d955687abbc7cff3549f626c2ca9 848 SUPERFAMILY SSF55874 532 694 5.89E-41 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_15850 9948d955687abbc7cff3549f626c2ca9 848 Pfam PF00072 Response regulator receiver domain 723 834 2.1E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_15850 9948d955687abbc7cff3549f626c2ca9 848 SUPERFAMILY SSF52172 721 844 2.85E-27 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_15850 9948d955687abbc7cff3549f626c2ca9 848 Pfam PF00989 PAS fold 203 312 1.6E-14 T 14-10-2018 IPR013767 PAS fold GO:0006355 TSH58p_15850 9948d955687abbc7cff3549f626c2ca9 848 SUPERFAMILY SSF55785 52 161 1.22E-12 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_15850 9948d955687abbc7cff3549f626c2ca9 848 SMART SM00388 476 541 8.0E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_16635 13d6c70bdd8493b6c69b30d4df545cb4 273 SMART SM00419 213 261 8.5E-10 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_16635 13d6c70bdd8493b6c69b30d4df545cb4 273 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 124 141 - T 14-10-2018 IPR018488 Cyclic nucleotide-binding, conserved site TSH58p_16635 13d6c70bdd8493b6c69b30d4df545cb4 273 SMART SM00100 56 174 9.9E-26 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_16635 13d6c70bdd8493b6c69b30d4df545cb4 273 Gene3D G3DSA:1.10.10.10 193 270 1.8E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_16635 13d6c70bdd8493b6c69b30d4df545cb4 273 SUPERFAMILY SSF46785 192 269 9.98E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_16635 13d6c70bdd8493b6c69b30d4df545cb4 273 Pfam PF00027 Cyclic nucleotide-binding domain 76 160 1.7E-24 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_16635 13d6c70bdd8493b6c69b30d4df545cb4 273 Gene3D G3DSA:2.60.120.10 46 192 6.3E-43 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_16635 13d6c70bdd8493b6c69b30d4df545cb4 273 Pfam PF13545 Crp-like helix-turn-helix domain 195 268 1.2E-16 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_16635 13d6c70bdd8493b6c69b30d4df545cb4 273 SUPERFAMILY SSF51206 51 186 1.44E-37 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like TSH58p_16635 13d6c70bdd8493b6c69b30d4df545cb4 273 PRINTS PR00103 cAMP-dependent protein kinase signature 77 91 7.2E-5 T 14-10-2018 TSH58p_16635 13d6c70bdd8493b6c69b30d4df545cb4 273 PRINTS PR00103 cAMP-dependent protein kinase signature 122 131 7.2E-5 T 14-10-2018 TSH58p_16635 13d6c70bdd8493b6c69b30d4df545cb4 273 PRINTS PR00103 cAMP-dependent protein kinase signature 134 145 7.2E-5 T 14-10-2018 TSH58p_19265 9fec3a327774582e7a22673d2184fae8 318 Pfam PF00892 EamA-like transporter family 30 161 2.9E-17 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_19265 9fec3a327774582e7a22673d2184fae8 318 Pfam PF00892 EamA-like transporter family 171 295 3.8E-13 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_19265 9fec3a327774582e7a22673d2184fae8 318 SUPERFAMILY SSF103481 206 304 3.4E-12 T 14-10-2018 TSH58p_19265 9fec3a327774582e7a22673d2184fae8 318 SUPERFAMILY SSF103481 70 165 5.23E-17 T 14-10-2018 TSH58p_04700 3e5a50a66d7718114552cb71762141d2 203 Pfam PF01066 CDP-alcohol phosphatidyltransferase 5 71 3.2E-16 T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TSH58p_04700 3e5a50a66d7718114552cb71762141d2 203 Gene3D G3DSA:1.20.120.1760 3 177 2.6E-13 T 14-10-2018 TSH58p_04700 3e5a50a66d7718114552cb71762141d2 203 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 49 71 - T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TSH58p_04700 3e5a50a66d7718114552cb71762141d2 203 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 4 181 1.8E-46 T 14-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 TSH58p_04700 3e5a50a66d7718114552cb71762141d2 203 PIRSF PIRSF000847 1 190 8.9E-45 T 14-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 TSH58p_25920 058b37a059646c461919a9f8618e6822 383 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 12 356 3.2E-138 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 TSH58p_25920 058b37a059646c461919a9f8618e6822 383 Gene3D G3DSA:3.30.413.10 265 366 4.8E-26 T 14-10-2018 TSH58p_25920 058b37a059646c461919a9f8618e6822 383 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 10 361 33.662 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 TSH58p_25920 058b37a059646c461919a9f8618e6822 383 Gene3D G3DSA:3.20.20.20 2 264 2.1E-105 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSH58p_25920 058b37a059646c461919a9f8618e6822 383 Pfam PF04551 GcpE protein 16 357 3.7E-132 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 TSH58p_25920 058b37a059646c461919a9f8618e6822 383 SUPERFAMILY SSF51366 25 174 3.58E-8 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TSH58p_25920 058b37a059646c461919a9f8618e6822 383 SUPERFAMILY SSF56014 269 352 2.06E-13 T 14-10-2018 TSH58p_25920 058b37a059646c461919a9f8618e6822 383 PIRSF PIRSF004640 4 367 6.9E-148 T 14-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 TSH58p_06430 7fd6553d9f3ed547863696043a33a845 297 Gene3D G3DSA:3.20.20.70 19 270 1.3E-83 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_06430 7fd6553d9f3ed547863696043a33a845 297 SMART SM01133 26 256 4.2E-63 T 14-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TSH58p_06430 7fd6553d9f3ed547863696043a33a845 297 SUPERFAMILY SSF51569 26 255 2.3E-71 T 14-10-2018 TSH58p_06430 7fd6553d9f3ed547863696043a33a845 297 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 29 238 1.1E-59 T 14-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TSH58p_06430 7fd6553d9f3ed547863696043a33a845 297 PIRSF PIRSF001357 21 264 6.4E-67 T 14-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TSH58p_06430 7fd6553d9f3ed547863696043a33a845 297 Pfam PF01791 DeoC/LacD family aldolase 28 253 5.1E-29 T 14-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TSH58p_01270 d7d83f7f204fa00bc0bb28801382d6c2 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 1.4E-10 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_01270 d7d83f7f204fa00bc0bb28801382d6c2 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 96 109 1.4E-10 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_01270 d7d83f7f204fa00bc0bb28801382d6c2 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 221 235 1.4E-10 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_01270 d7d83f7f204fa00bc0bb28801382d6c2 278 Pfam PF12146 Serine aminopeptidase, S33 28 260 3.1E-20 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 TSH58p_01270 d7d83f7f204fa00bc0bb28801382d6c2 278 SUPERFAMILY SSF53474 5 277 5.36E-63 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_01270 d7d83f7f204fa00bc0bb28801382d6c2 278 PRINTS PR00412 Epoxide hydrolase signature 32 50 5.2E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TSH58p_01270 d7d83f7f204fa00bc0bb28801382d6c2 278 PRINTS PR00412 Epoxide hydrolase signature 52 67 5.2E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TSH58p_01270 d7d83f7f204fa00bc0bb28801382d6c2 278 PRINTS PR00412 Epoxide hydrolase signature 219 235 5.2E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TSH58p_01270 d7d83f7f204fa00bc0bb28801382d6c2 278 Gene3D G3DSA:3.40.50.1820 3 277 5.5E-77 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_05180 4f49aa8bdd43e574a963b6c730b86e93 464 Gene3D G3DSA:3.40.50.1220 287 463 8.8E-85 T 14-10-2018 TSH58p_05180 4f49aa8bdd43e574a963b6c730b86e93 464 Pfam PF02233 NAD(P) transhydrogenase beta subunit 7 461 7.7E-200 T 14-10-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 TSH58p_05180 4f49aa8bdd43e574a963b6c730b86e93 464 SUPERFAMILY SSF52467 290 462 6.22E-76 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TSH58p_05180 4f49aa8bdd43e574a963b6c730b86e93 464 PIRSF PIRSF000204 1 464 3.6E-218 T 14-10-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 TSH58p_21835 50704efcbdadb5754b1e653d073d02f1 157 Gene3D G3DSA:1.10.10.10 93 157 5.1E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_21835 50704efcbdadb5754b1e653d073d02f1 157 Pfam PF08281 Sigma-70, region 4 100 151 2.0E-16 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_21835 50704efcbdadb5754b1e653d073d02f1 157 Pfam PF04542 Sigma-70 region 2 12 74 1.8E-10 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_21835 50704efcbdadb5754b1e653d073d02f1 157 Gene3D G3DSA:1.10.1740.10 2 76 1.1E-16 T 14-10-2018 TSH58p_21835 50704efcbdadb5754b1e653d073d02f1 157 SUPERFAMILY SSF88659 94 155 5.23E-14 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSH58p_21835 50704efcbdadb5754b1e653d073d02f1 157 SUPERFAMILY SSF88946 5 83 1.84E-15 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_21835 50704efcbdadb5754b1e653d073d02f1 157 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 153 1.6E-21 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TSH58p_13320 980c6fcd16d9d3dfe4733118f7933311 479 SUPERFAMILY SSF103473 4 453 1.83E-58 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_13320 980c6fcd16d9d3dfe4733118f7933311 479 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 12 412 8.7E-71 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 TSH58p_13320 980c6fcd16d9d3dfe4733118f7933311 479 Gene3D G3DSA:1.20.1250.20 255 458 4.6E-13 T 14-10-2018 TSH58p_13320 980c6fcd16d9d3dfe4733118f7933311 479 Gene3D G3DSA:1.20.1720.10 10 240 4.9E-48 T 14-10-2018 TSH58p_13320 980c6fcd16d9d3dfe4733118f7933311 479 Pfam PF07690 Major Facilitator Superfamily 12 403 2.5E-46 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_29760 43c99b0a35c4ae4686776bd8590dd88a 317 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 20 98 9.1E-26 T 14-10-2018 IPR013589 Bacterial transglutaminase-like, N-terminal TSH58p_29760 43c99b0a35c4ae4686776bd8590dd88a 317 SUPERFAMILY SSF54001 83 310 3.92E-39 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily TSH58p_29760 43c99b0a35c4ae4686776bd8590dd88a 317 SMART SM00460 193 264 2.9E-17 T 14-10-2018 IPR002931 Transglutaminase-like TSH58p_29760 43c99b0a35c4ae4686776bd8590dd88a 317 Pfam PF01841 Transglutaminase-like superfamily 157 260 3.4E-18 T 14-10-2018 IPR002931 Transglutaminase-like TSH58p_29760 43c99b0a35c4ae4686776bd8590dd88a 317 Gene3D G3DSA:3.10.620.30 113 298 2.6E-44 T 14-10-2018 TSH58p_29040 6b62f95b62891a61b00faa6f97ffc0b6 301 Gene3D G3DSA:3.40.190.10 94 293 5.4E-52 T 14-10-2018 TSH58p_29040 6b62f95b62891a61b00faa6f97ffc0b6 301 SUPERFAMILY SSF53850 92 299 3.41E-38 T 14-10-2018 TSH58p_29040 6b62f95b62891a61b00faa6f97ffc0b6 301 Gene3D G3DSA:3.40.190.10 166 268 5.4E-52 T 14-10-2018 TSH58p_29040 6b62f95b62891a61b00faa6f97ffc0b6 301 Gene3D G3DSA:1.10.10.10 4 91 2.6E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_29040 6b62f95b62891a61b00faa6f97ffc0b6 301 SUPERFAMILY SSF46785 5 113 3.71E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_29040 6b62f95b62891a61b00faa6f97ffc0b6 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 1.8E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_29040 6b62f95b62891a61b00faa6f97ffc0b6 301 Pfam PF03466 LysR substrate binding domain 90 295 7.0E-35 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_17165 f3cc82ba1631e36ad3274788c20c79a1 232 SUPERFAMILY SSF144091 5 202 5.1E-33 T 14-10-2018 TSH58p_17165 f3cc82ba1631e36ad3274788c20c79a1 232 Gene3D G3DSA:1.20.1540.10 4 205 3.7E-29 T 14-10-2018 IPR035952 Rhomboid-like superfamily TSH58p_17165 f3cc82ba1631e36ad3274788c20c79a1 232 Pfam PF01694 Rhomboid family 51 201 2.6E-34 T 14-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 TSH58p_10565 f6ab8d606027fa27a34b95cb4e313cbe 375 SMART SM00267 200 368 8.1E-51 T 14-10-2018 IPR000160 GGDEF domain TSH58p_10565 f6ab8d606027fa27a34b95cb4e313cbe 375 Pfam PF00990 Diguanylate cyclase, GGDEF domain 210 364 1.1E-40 T 14-10-2018 IPR000160 GGDEF domain TSH58p_10565 f6ab8d606027fa27a34b95cb4e313cbe 375 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 208 367 5.3E-46 T 14-10-2018 IPR000160 GGDEF domain TSH58p_10565 f6ab8d606027fa27a34b95cb4e313cbe 375 Gene3D G3DSA:3.30.70.270 203 368 3.8E-48 T 14-10-2018 TSH58p_10565 f6ab8d606027fa27a34b95cb4e313cbe 375 SUPERFAMILY SSF55073 215 367 2.51E-41 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_28675 88eb7c8cd1efd6dca72d274635dd6261 250 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 75 233 4.1E-7 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 TSH58p_28675 88eb7c8cd1efd6dca72d274635dd6261 250 Gene3D G3DSA:3.90.850.10 1 250 2.5E-61 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TSH58p_28675 88eb7c8cd1efd6dca72d274635dd6261 250 SUPERFAMILY SSF56529 1 249 6.54E-42 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TSH58p_03025 74f863d9f0238e9d91be7b0a7061ac3a 268 Gene3D G3DSA:1.10.3720.10 63 254 4.9E-26 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_03025 74f863d9f0238e9d91be7b0a7061ac3a 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 249 3.3E-23 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_03025 74f863d9f0238e9d91be7b0a7061ac3a 268 SUPERFAMILY SSF161098 62 244 7.19E-32 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_09965 9578021be393c5c7a1f8bf032be2c7ee 288 Gene3D G3DSA:3.40.50.150 54 268 3.8E-51 T 14-10-2018 TSH58p_09965 9578021be393c5c7a1f8bf032be2c7ee 288 Pfam PF13649 Methyltransferase domain 58 158 6.0E-17 T 14-10-2018 TSH58p_09965 9578021be393c5c7a1f8bf032be2c7ee 288 Gene3D G3DSA:2.20.25.570 166 235 3.8E-51 T 14-10-2018 TSH58p_09965 9578021be393c5c7a1f8bf032be2c7ee 288 SUPERFAMILY SSF53335 51 276 3.01E-34 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_22380 2116d55f52350899419bd336d191269b 681 SMART SM00304 331 384 0.0035 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_22380 2116d55f52350899419bd336d191269b 681 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 485 640 3.8E-29 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_22380 2116d55f52350899419bd336d191269b 681 SUPERFAMILY SSF58104 359 674 6.8E-60 T 14-10-2018 TSH58p_22380 2116d55f52350899419bd336d191269b 681 Gene3D G3DSA:3.30.450.20 52 200 3.0E-65 T 14-10-2018 TSH58p_22380 2116d55f52350899419bd336d191269b 681 Pfam PF02743 Cache domain 36 292 1.2E-18 T 14-10-2018 IPR033479 Double Cache domain 1 TSH58p_22380 2116d55f52350899419bd336d191269b 681 Gene3D G3DSA:1.10.287.950 389 679 1.6E-52 T 14-10-2018 TSH58p_22380 2116d55f52350899419bd336d191269b 681 Gene3D G3DSA:1.20.1480.50 299 388 1.7E-6 T 14-10-2018 TSH58p_22380 2116d55f52350899419bd336d191269b 681 Gene3D G3DSA:3.30.450.20 41 298 3.0E-65 T 14-10-2018 TSH58p_22380 2116d55f52350899419bd336d191269b 681 SMART SM00283 421 675 1.5E-44 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_10130 02d845da2a3f42e6162d22b405e10b83 195 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 156 173 3.9E-9 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_10130 02d845da2a3f42e6162d22b405e10b83 195 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 173 193 3.9E-9 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_10130 02d845da2a3f42e6162d22b405e10b83 195 SUPERFAMILY SSF46689 143 192 1.4E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_10130 02d845da2a3f42e6162d22b405e10b83 195 SUPERFAMILY SSF52172 3 137 2.85E-17 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_10130 02d845da2a3f42e6162d22b405e10b83 195 SMART SM00448 4 121 3.1E-4 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_10130 02d845da2a3f42e6162d22b405e10b83 195 Pfam PF02954 Bacterial regulatory protein, Fis family 151 185 1.8E-10 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_10130 02d845da2a3f42e6162d22b405e10b83 195 Gene3D G3DSA:1.10.10.60 143 194 2.6E-13 T 14-10-2018 TSH58p_10130 02d845da2a3f42e6162d22b405e10b83 195 Gene3D G3DSA:3.40.50.2300 4 142 4.5E-15 T 14-10-2018 TSH58p_10130 02d845da2a3f42e6162d22b405e10b83 195 Pfam PF00072 Response regulator receiver domain 7 120 3.1E-9 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_27630 87b9f04297327ae27dc933375180fdf7 160 SUPERFAMILY SSF46785 28 158 5.01E-30 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_27630 87b9f04297327ae27dc933375180fdf7 160 SMART SM00347 48 148 2.6E-20 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_27630 87b9f04297327ae27dc933375180fdf7 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 88 5.9E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_27630 87b9f04297327ae27dc933375180fdf7 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 104 5.9E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_27630 87b9f04297327ae27dc933375180fdf7 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 108 124 5.9E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_27630 87b9f04297327ae27dc933375180fdf7 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 138 158 5.9E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_27630 87b9f04297327ae27dc933375180fdf7 160 Gene3D G3DSA:1.10.10.10 24 159 1.0E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_27630 87b9f04297327ae27dc933375180fdf7 160 Pfam PF01047 MarR family 55 111 2.0E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_23855 49e2bd340e1d3eb588a441561712a3f6 638 SUPERFAMILY SSF52518 7 383 1.11E-79 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_23855 49e2bd340e1d3eb588a441561712a3f6 638 Pfam PF02780 Transketolase, C-terminal domain 498 621 1.5E-26 T 14-10-2018 IPR033248 Transketolase, C-terminal domain TSH58p_23855 49e2bd340e1d3eb588a441561712a3f6 638 SUPERFAMILY SSF52518 318 507 1.59E-55 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_23855 49e2bd340e1d3eb588a441561712a3f6 638 SUPERFAMILY SSF52922 493 629 3.01E-32 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSH58p_23855 49e2bd340e1d3eb588a441561712a3f6 638 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 9 630 44.073 T 14-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TSH58p_23855 49e2bd340e1d3eb588a441561712a3f6 638 Gene3D G3DSA:3.40.50.970 318 491 6.0E-60 T 14-10-2018 TSH58p_23855 49e2bd340e1d3eb588a441561712a3f6 638 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 10 284 2.8E-120 T 14-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TSH58p_23855 49e2bd340e1d3eb588a441561712a3f6 638 Pfam PF02779 Transketolase, pyrimidine binding domain 321 481 1.3E-35 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSH58p_23855 49e2bd340e1d3eb588a441561712a3f6 638 SMART SM00861 321 486 1.2E-60 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSH58p_23855 49e2bd340e1d3eb588a441561712a3f6 638 Gene3D G3DSA:3.40.50.920 498 630 1.3E-34 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSH58p_23855 49e2bd340e1d3eb588a441561712a3f6 638 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 12 626 6.9E-241 T 14-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TSH58p_23855 49e2bd340e1d3eb588a441561712a3f6 638 ProSitePatterns PS00801 Transketolase signature 1. 35 54 - T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TSH58p_23855 49e2bd340e1d3eb588a441561712a3f6 638 ProSitePatterns PS00802 Transketolase signature 2. 427 443 - T 14-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TSH58p_25715 8a20e7180e0c0fc22f2e524b859f4b51 174 Pfam PF11749 Protein of unknown function (DUF3305) 10 149 2.0E-42 T 14-10-2018 IPR021736 Protein of unknown function DUF3305 TSH58p_21900 0c9c79fa69afd8dbc0582bf7eecb4203 160 TIGRFAM TIGR02944 suf_reg_Xantho: FeS assembly SUF system regulator 1 131 1.0E-39 T 14-10-2018 IPR014290 SUF system FeS cluster assembly regulator TSH58p_21900 0c9c79fa69afd8dbc0582bf7eecb4203 160 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 14-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site TSH58p_21900 0c9c79fa69afd8dbc0582bf7eecb4203 160 Gene3D G3DSA:1.10.10.10 1 137 6.2E-37 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_21900 0c9c79fa69afd8dbc0582bf7eecb4203 160 Pfam PF02082 Transcriptional regulator 3 83 3.5E-20 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type TSH58p_21900 0c9c79fa69afd8dbc0582bf7eecb4203 160 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 3 132 2.2E-30 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type TSH58p_21900 0c9c79fa69afd8dbc0582bf7eecb4203 160 SUPERFAMILY SSF46785 3 134 1.54E-33 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_17865 39ca8b0c03fad659764f55e02cb008bc 348 Pfam PF05045 Rhamnan synthesis protein F 89 241 1.4E-26 T 14-10-2018 IPR007739 Rhamnan synthesis F TSH58p_27825 ec77af88a8b4d02711ff3cae3ab7f081 329 Pfam PF01207 Dihydrouridine synthase (Dus) 8 306 3.0E-84 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 TSH58p_27825 ec77af88a8b4d02711ff3cae3ab7f081 329 TIGRFAM TIGR00742 yjbN: tRNA dihydrouridine synthase A 6 318 3.8E-142 T 14-10-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 TSH58p_27825 ec77af88a8b4d02711ff3cae3ab7f081 329 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 2 320 52.035 T 14-10-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 TSH58p_27825 ec77af88a8b4d02711ff3cae3ab7f081 329 SUPERFAMILY SSF51395 6 299 1.1E-71 T 14-10-2018 TSH58p_27825 ec77af88a8b4d02711ff3cae3ab7f081 329 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 87 105 - T 14-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 TSH58p_27825 ec77af88a8b4d02711ff3cae3ab7f081 329 PIRSF PIRSF006621 2 304 3.1E-73 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 TSH58p_27825 ec77af88a8b4d02711ff3cae3ab7f081 329 Gene3D G3DSA:3.20.20.70 4 244 3.7E-74 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_27825 ec77af88a8b4d02711ff3cae3ab7f081 329 Gene3D G3DSA:1.20.120.1460 245 314 2.5E-21 T 14-10-2018 TSH58p_12240 16700c0cc20b8339330d62cfc9d9ac11 171 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 16 135 1.3E-34 T 14-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 TSH58p_12240 16700c0cc20b8339330d62cfc9d9ac11 171 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 15 147 6.5E-29 T 14-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 TSH58p_12240 16700c0cc20b8339330d62cfc9d9ac11 171 Gene3D G3DSA:3.40.50.300 9 158 4.9E-37 T 14-10-2018 TSH58p_12240 16700c0cc20b8339330d62cfc9d9ac11 171 SUPERFAMILY SSF52540 31 137 3.98E-15 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_21720 90ac8eee929f014d297a2d670419552a 219 SUPERFAMILY SSF46689 9 87 2.67E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_21720 90ac8eee929f014d297a2d670419552a 219 Gene3D G3DSA:1.10.10.60 6 66 1.2E-17 T 14-10-2018 TSH58p_21720 90ac8eee929f014d297a2d670419552a 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 69 9.9E-15 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_21720 90ac8eee929f014d297a2d670419552a 219 Gene3D G3DSA:1.10.357.10 67 213 2.6E-25 T 14-10-2018 TSH58p_21720 90ac8eee929f014d297a2d670419552a 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 4.4E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_21720 90ac8eee929f014d297a2d670419552a 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 4.4E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_21720 90ac8eee929f014d297a2d670419552a 219 SUPERFAMILY SSF48498 90 212 3.4E-23 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TSH58p_21720 90ac8eee929f014d297a2d670419552a 219 Pfam PF16859 Bacterial transcriptional repressor C-terminal 89 182 5.2E-13 T 14-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal TSH58p_03920 6027c59f90fe76b0291788ea0ea776e5 292 SMART SM00062 63 287 1.3E-43 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_03920 6027c59f90fe76b0291788ea0ea776e5 292 Gene3D G3DSA:3.40.190.10 55 274 1.9E-59 T 14-10-2018 TSH58p_03920 6027c59f90fe76b0291788ea0ea776e5 292 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 64 283 5.1E-42 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_03920 6027c59f90fe76b0291788ea0ea776e5 292 SUPERFAMILY SSF53850 64 283 2.93E-49 T 14-10-2018 TSH58p_03920 6027c59f90fe76b0291788ea0ea776e5 292 Gene3D G3DSA:3.40.190.10 151 241 1.9E-59 T 14-10-2018 TSH58p_07395 bf55ab75eb2f8646f9b695b52e36cb44 358 SUPERFAMILY SSF53067 4 323 8.42E-20 T 14-10-2018 TSH58p_07395 bf55ab75eb2f8646f9b695b52e36cb44 358 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 3 357 1.2E-93 T 14-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 TSH58p_07395 bf55ab75eb2f8646f9b695b52e36cb44 358 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 2 358 39.34 T 14-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 TSH58p_07395 bf55ab75eb2f8646f9b695b52e36cb44 358 Gene3D G3DSA:3.30.420.40 5 349 2.1E-116 T 14-10-2018 TSH58p_07395 bf55ab75eb2f8646f9b695b52e36cb44 358 Gene3D G3DSA:3.30.420.40 138 318 2.1E-116 T 14-10-2018 TSH58p_15905 18fa55118b0213b3a5f51c274111f31c 338 SUPERFAMILY SSF102114 33 315 7.19E-43 T 14-10-2018 TSH58p_15905 18fa55118b0213b3a5f51c274111f31c 338 Pfam PF04055 Radical SAM superfamily 41 182 3.0E-16 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSH58p_15905 18fa55118b0213b3a5f51c274111f31c 338 Pfam PF13186 Iron-sulfur cluster-binding domain 247 313 4.5E-15 T 14-10-2018 IPR023885 4Fe4S-binding SPASM domain TSH58p_15905 18fa55118b0213b3a5f51c274111f31c 338 SMART SM00729 35 249 0.0026 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSH58p_08725 eb9cce8dd814c2495540ec50e283a6ac 229 Gene3D G3DSA:2.40.33.20 2 229 1.8E-82 T 14-10-2018 TSH58p_08725 eb9cce8dd814c2495540ec50e283a6ac 229 Pfam PF03473 MOSC domain 49 164 2.1E-26 T 14-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 TSH58p_08725 eb9cce8dd814c2495540ec50e283a6ac 229 SUPERFAMILY SSF50800 4 227 5.13E-75 T 14-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily TSH58p_08725 eb9cce8dd814c2495540ec50e283a6ac 229 Pfam PF03475 3-alpha domain 174 217 2.3E-15 T 14-10-2018 IPR005163 3-alpha domain TSH58p_26110 e610a2adc8ed0e8d28684d67829530f7 325 Gene3D G3DSA:1.10.3470.10 2 325 7.6E-66 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_26110 e610a2adc8ed0e8d28684d67829530f7 325 SUPERFAMILY SSF81345 6 320 9.15E-65 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_26110 e610a2adc8ed0e8d28684d67829530f7 325 Pfam PF01032 FecCD transport family 15 319 1.0E-68 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TSH58p_22965 60c304db99d4271b1754e9d07c058b6c 875 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 509 866 9.6E-151 T 14-10-2018 IPR017777 Urea ABC transporter, substrate-binding protein UrtA-like TSH58p_22965 60c304db99d4271b1754e9d07c058b6c 875 Pfam PF13433 Periplasmic binding protein domain 509 868 8.9E-129 T 14-10-2018 TSH58p_22965 60c304db99d4271b1754e9d07c058b6c 875 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 264 424 3.8E-29 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_22965 60c304db99d4271b1754e9d07c058b6c 875 SMART SM00283 202 456 2.4E-39 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_22965 60c304db99d4271b1754e9d07c058b6c 875 Gene3D G3DSA:3.40.50.2300 624 857 5.1E-130 T 14-10-2018 TSH58p_22965 60c304db99d4271b1754e9d07c058b6c 875 Gene3D G3DSA:3.40.50.2300 511 838 5.1E-130 T 14-10-2018 TSH58p_22965 60c304db99d4271b1754e9d07c058b6c 875 Gene3D G3DSA:1.10.287.950 169 467 2.9E-51 T 14-10-2018 TSH58p_22965 60c304db99d4271b1754e9d07c058b6c 875 SUPERFAMILY SSF58104 183 455 5.49E-58 T 14-10-2018 TSH58p_22965 60c304db99d4271b1754e9d07c058b6c 875 SUPERFAMILY SSF53822 509 866 9.71E-91 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_22965 60c304db99d4271b1754e9d07c058b6c 875 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 219 248 5.1E-18 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_22965 60c304db99d4271b1754e9d07c058b6c 875 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 329 358 5.1E-18 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_22965 60c304db99d4271b1754e9d07c058b6c 875 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 300 327 5.1E-18 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_01120 e54f2e17a096ce3c037c6d236e928d2e 455 SUPERFAMILY SSF51717 126 330 1.57E-26 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSH58p_27910 6f7ec56dc06fdcd9ebf04954cd2fc1f3 596 Gene3D G3DSA:2.40.110.10 160 280 6.2E-92 T 14-10-2018 TSH58p_27910 6f7ec56dc06fdcd9ebf04954cd2fc1f3 596 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 79 156 1.6E-8 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TSH58p_27910 6f7ec56dc06fdcd9ebf04954cd2fc1f3 596 SUPERFAMILY SSF47203 286 460 7.57E-47 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TSH58p_27910 6f7ec56dc06fdcd9ebf04954cd2fc1f3 596 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 282 450 1.2E-21 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TSH58p_27910 6f7ec56dc06fdcd9ebf04954cd2fc1f3 596 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 472 592 4.6E-39 T 14-10-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain TSH58p_27910 6f7ec56dc06fdcd9ebf04954cd2fc1f3 596 SUPERFAMILY SSF56645 39 279 4.71E-56 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TSH58p_27910 6f7ec56dc06fdcd9ebf04954cd2fc1f3 596 Gene3D G3DSA:1.20.140.10 281 448 6.2E-92 T 14-10-2018 TSH58p_27910 6f7ec56dc06fdcd9ebf04954cd2fc1f3 596 Gene3D G3DSA:1.10.540.10 46 159 6.2E-92 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TSH58p_27910 6f7ec56dc06fdcd9ebf04954cd2fc1f3 596 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 4 34 2.1E-10 T 14-10-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria TSH58p_27910 6f7ec56dc06fdcd9ebf04954cd2fc1f3 596 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 271 2.0E-18 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TSH58p_12090 ea10a3ffe6dcd8a0683119810976bb44 239 Pfam PF01578 Cytochrome C assembly protein 8 180 1.7E-30 T 14-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 TSH58p_12090 ea10a3ffe6dcd8a0683119810976bb44 239 TIGRFAM TIGR01191 ccmC: heme exporter protein CcmC 41 224 6.7E-85 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSH58p_12090 ea10a3ffe6dcd8a0683119810976bb44 239 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 117 137 1.3E-60 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSH58p_12090 ea10a3ffe6dcd8a0683119810976bb44 239 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 152 178 1.3E-60 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSH58p_12090 ea10a3ffe6dcd8a0683119810976bb44 239 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 96 116 1.3E-60 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSH58p_12090 ea10a3ffe6dcd8a0683119810976bb44 239 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 200 224 1.3E-60 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSH58p_12090 ea10a3ffe6dcd8a0683119810976bb44 239 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 41 58 1.3E-60 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSH58p_12090 ea10a3ffe6dcd8a0683119810976bb44 239 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 58 78 1.3E-60 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSH58p_27570 80f2be6a04f977bfb8f1acec8454aa67 353 Gene3D G3DSA:3.40.50.300 129 332 4.4E-39 T 14-10-2018 TSH58p_27570 80f2be6a04f977bfb8f1acec8454aa67 353 Pfam PF00448 SRP54-type protein, GTPase domain 138 322 1.9E-27 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSH58p_27570 80f2be6a04f977bfb8f1acec8454aa67 353 SUPERFAMILY SSF52540 134 306 1.2E-20 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_27570 80f2be6a04f977bfb8f1acec8454aa67 353 SMART SM00962 135 324 3.4E-22 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSH58p_27570 80f2be6a04f977bfb8f1acec8454aa67 353 SMART SM00382 134 313 9.5E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_17795 32ef7299c5628e8c24a1a5a3dcd38adf 313 SUPERFAMILY SSF53335 25 199 8.26E-15 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_17795 32ef7299c5628e8c24a1a5a3dcd38adf 313 Gene3D G3DSA:3.40.50.150 59 202 4.0E-14 T 14-10-2018 TSH58p_17795 32ef7299c5628e8c24a1a5a3dcd38adf 313 Pfam PF13847 Methyltransferase domain 100 195 3.6E-7 T 14-10-2018 IPR025714 Methyltransferase domain TSH58p_28890 5f10a5a9eacf8b530127ed03f2d50949 320 Gene3D G3DSA:3.40.50.1370 15 308 5.1E-93 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TSH58p_28890 5f10a5a9eacf8b530127ed03f2d50949 320 PRINTS PR00101 Aspartate carbamoyltransferase signature 268 273 1.2E-29 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSH58p_28890 5f10a5a9eacf8b530127ed03f2d50949 320 PRINTS PR00101 Aspartate carbamoyltransferase signature 143 160 1.2E-29 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSH58p_28890 5f10a5a9eacf8b530127ed03f2d50949 320 PRINTS PR00101 Aspartate carbamoyltransferase signature 293 307 1.2E-29 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSH58p_28890 5f10a5a9eacf8b530127ed03f2d50949 320 PRINTS PR00101 Aspartate carbamoyltransferase signature 50 72 1.2E-29 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSH58p_28890 5f10a5a9eacf8b530127ed03f2d50949 320 PRINTS PR00101 Aspartate carbamoyltransferase signature 88 97 1.2E-29 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSH58p_28890 5f10a5a9eacf8b530127ed03f2d50949 320 PRINTS PR00101 Aspartate carbamoyltransferase signature 227 236 1.2E-29 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSH58p_28890 5f10a5a9eacf8b530127ed03f2d50949 320 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 264 273 1.9E-12 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSH58p_28890 5f10a5a9eacf8b530127ed03f2d50949 320 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 60 79 1.9E-12 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSH58p_28890 5f10a5a9eacf8b530127ed03f2d50949 320 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 144 155 1.9E-12 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSH58p_28890 5f10a5a9eacf8b530127ed03f2d50949 320 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 164 310 2.0E-23 T 14-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 TSH58p_28890 5f10a5a9eacf8b530127ed03f2d50949 320 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 14 312 1.1E-93 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSH58p_28890 5f10a5a9eacf8b530127ed03f2d50949 320 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 14 156 9.2E-42 T 14-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 TSH58p_28890 5f10a5a9eacf8b530127ed03f2d50949 320 SUPERFAMILY SSF53671 11 313 1.57E-97 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TSH58p_28890 5f10a5a9eacf8b530127ed03f2d50949 320 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 13 314 40.057 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSH58p_28890 5f10a5a9eacf8b530127ed03f2d50949 320 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 60 67 - T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSH58p_28890 5f10a5a9eacf8b530127ed03f2d50949 320 Gene3D G3DSA:3.40.50.1370 144 299 5.1E-93 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TSH58p_02115 599d85d3c983c1a24b3da1a9c6aa9f2e 239 Gene3D G3DSA:2.150.10.10 4 63 1.0E-10 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_02115 599d85d3c983c1a24b3da1a9c6aa9f2e 239 Gene3D G3DSA:2.150.10.10 118 207 9.6E-8 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_02115 599d85d3c983c1a24b3da1a9c6aa9f2e 239 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 79 97 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_02115 599d85d3c983c1a24b3da1a9c6aa9f2e 239 Gene3D G3DSA:2.150.10.10 64 117 8.4E-15 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_02115 599d85d3c983c1a24b3da1a9c6aa9f2e 239 SUPERFAMILY SSF51120 8 196 2.77E-29 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_02115 599d85d3c983c1a24b3da1a9c6aa9f2e 239 PRINTS PR00313 NodO calcium binding signature 123 131 4.2E-13 T 14-10-2018 TSH58p_02115 599d85d3c983c1a24b3da1a9c6aa9f2e 239 PRINTS PR00313 NodO calcium binding signature 101 109 4.2E-13 T 14-10-2018 TSH58p_02115 599d85d3c983c1a24b3da1a9c6aa9f2e 239 PRINTS PR00313 NodO calcium binding signature 132 141 4.2E-13 T 14-10-2018 TSH58p_02115 599d85d3c983c1a24b3da1a9c6aa9f2e 239 PRINTS PR00313 NodO calcium binding signature 44 55 4.2E-13 T 14-10-2018 TSH58p_02115 599d85d3c983c1a24b3da1a9c6aa9f2e 239 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 123 138 0.0069 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_02115 599d85d3c983c1a24b3da1a9c6aa9f2e 239 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 64 81 0.0076 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_02115 599d85d3c983c1a24b3da1a9c6aa9f2e 239 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 10 18 34.0 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_02115 599d85d3c983c1a24b3da1a9c6aa9f2e 239 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 47 63 0.0014 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_02115 599d85d3c983c1a24b3da1a9c6aa9f2e 239 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 28 45 18.0 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_02115 599d85d3c983c1a24b3da1a9c6aa9f2e 239 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 83 99 0.14 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_02115 599d85d3c983c1a24b3da1a9c6aa9f2e 239 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 100 116 0.0023 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_01145 7d82502015b1cb4021010792a1f9a497 271 PIRSF PIRSF006648 4 258 1.6E-33 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSH58p_01145 7d82502015b1cb4021010792a1f9a497 271 Pfam PF01061 ABC-2 type transporter 10 228 1.4E-35 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TSH58p_01145 7d82502015b1cb4021010792a1f9a497 271 PRINTS PR00164 ABC-2 type transport system membrane protein signature 28 49 4.6E-8 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSH58p_01145 7d82502015b1cb4021010792a1f9a497 271 PRINTS PR00164 ABC-2 type transport system membrane protein signature 145 169 4.6E-8 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSH58p_01145 7d82502015b1cb4021010792a1f9a497 271 PRINTS PR00164 ABC-2 type transport system membrane protein signature 182 201 4.6E-8 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSH58p_01145 7d82502015b1cb4021010792a1f9a497 271 TIGRFAM TIGR03861 phenyl_ABC_PedC: alcohol ABC transporter, permease protein 7 258 2.2E-121 T 14-10-2018 IPR022403 Alcohol ABC transporter, permease protein TSH58p_06290 a839541b71c95682903a6014c5ee3dcf 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 250 4.3E-55 T 14-10-2018 TSH58p_06290 a839541b71c95682903a6014c5ee3dcf 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_06290 a839541b71c95682903a6014c5ee3dcf 251 SUPERFAMILY SSF51735 6 250 1.59E-67 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_06290 a839541b71c95682903a6014c5ee3dcf 251 Gene3D G3DSA:3.40.50.720 6 251 2.1E-70 T 14-10-2018 TSH58p_06290 a839541b71c95682903a6014c5ee3dcf 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 7.3E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_06290 a839541b71c95682903a6014c5ee3dcf 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 7.3E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_06290 a839541b71c95682903a6014c5ee3dcf 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 7.3E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_06290 a839541b71c95682903a6014c5ee3dcf 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 6.6E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_06290 a839541b71c95682903a6014c5ee3dcf 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 6.6E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_06290 a839541b71c95682903a6014c5ee3dcf 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 6.6E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_06290 a839541b71c95682903a6014c5ee3dcf 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 6.6E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_06290 a839541b71c95682903a6014c5ee3dcf 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 6.6E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_06290 a839541b71c95682903a6014c5ee3dcf 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 6.6E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_11485 f20354687728262633ba25afd26eda66 894 Gene3D G3DSA:3.40.630.30 721 890 2.3E-39 T 14-10-2018 TSH58p_11485 f20354687728262633ba25afd26eda66 894 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 148 284 3.2E-55 T 14-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain TSH58p_11485 f20354687728262633ba25afd26eda66 894 Pfam PF13549 ATP-grasp domain 477 698 3.5E-86 T 14-10-2018 TSH58p_11485 f20354687728262633ba25afd26eda66 894 Gene3D G3DSA:3.30.470.20 485 696 2.8E-78 T 14-10-2018 TSH58p_11485 f20354687728262633ba25afd26eda66 894 SMART SM00881 9 103 8.3E-29 T 14-10-2018 IPR003781 CoA-binding GO:0048037 TSH58p_11485 f20354687728262633ba25afd26eda66 894 SUPERFAMILY SSF55729 727 880 6.2E-20 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_11485 f20354687728262633ba25afd26eda66 894 Gene3D G3DSA:3.40.50.261 290 457 1.7E-49 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSH58p_11485 f20354687728262633ba25afd26eda66 894 SUPERFAMILY SSF51735 1 136 4.08E-30 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_11485 f20354687728262633ba25afd26eda66 894 Pfam PF13380 CoA binding domain 14 132 8.9E-18 T 14-10-2018 IPR003781 CoA-binding GO:0048037 TSH58p_11485 f20354687728262633ba25afd26eda66 894 Pfam PF00583 Acetyltransferase (GNAT) family 753 869 2.4E-9 T 14-10-2018 IPR000182 GNAT domain TSH58p_11485 f20354687728262633ba25afd26eda66 894 SUPERFAMILY SSF52210 293 450 1.26E-38 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSH58p_11485 f20354687728262633ba25afd26eda66 894 Gene3D G3DSA:3.40.50.720 3 126 6.5E-35 T 14-10-2018 TSH58p_11485 f20354687728262633ba25afd26eda66 894 SUPERFAMILY SSF52210 128 285 2.75E-45 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSH58p_11485 f20354687728262633ba25afd26eda66 894 Gene3D G3DSA:3.40.50.261 127 287 3.1E-58 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSH58p_11485 f20354687728262633ba25afd26eda66 894 Gene3D G3DSA:3.30.1490.20 503 580 2.8E-78 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSH58p_11485 f20354687728262633ba25afd26eda66 894 SUPERFAMILY SSF56059 485 702 2.14E-40 T 14-10-2018 TSH58p_24845 88ad0d10d084cfc19ab69c4b1d47f550 308 SUPERFAMILY SSF53335 82 248 3.63E-30 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_24845 88ad0d10d084cfc19ab69c4b1d47f550 308 Gene3D G3DSA:3.40.50.150 77 255 1.2E-28 T 14-10-2018 TSH58p_24845 88ad0d10d084cfc19ab69c4b1d47f550 308 Pfam PF13489 Methyltransferase domain 92 238 3.8E-15 T 14-10-2018 TSH58p_14015 6d3d9c64ffdc13d85f0ccf95f9fa3dbc 438 Gene3D G3DSA:3.40.50.300 6 257 2.4E-61 T 14-10-2018 TSH58p_14015 6d3d9c64ffdc13d85f0ccf95f9fa3dbc 438 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_14015 6d3d9c64ffdc13d85f0ccf95f9fa3dbc 438 SUPERFAMILY SSF52540 9 250 7.91E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_14015 6d3d9c64ffdc13d85f0ccf95f9fa3dbc 438 Pfam PF00005 ABC transporter 28 167 4.8E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_14015 6d3d9c64ffdc13d85f0ccf95f9fa3dbc 438 SMART SM00382 37 219 4.8E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_14015 6d3d9c64ffdc13d85f0ccf95f9fa3dbc 438 Pfam PF09821 C-terminal AAA-associated domain 308 426 9.8E-39 T 14-10-2018 IPR018632 C-terminal AAA-associated domain TSH58p_29225 cf5a4a33085e4b8d4c31dbf06c7ad7a0 370 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 114 191 3.8E-18 T 14-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TSH58p_29225 cf5a4a33085e4b8d4c31dbf06c7ad7a0 370 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 236 323 5.6E-25 T 14-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TSH58p_29225 cf5a4a33085e4b8d4c31dbf06c7ad7a0 370 Gene3D G3DSA:3.40.47.10 2 336 6.3E-113 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_29225 cf5a4a33085e4b8d4c31dbf06c7ad7a0 370 SUPERFAMILY SSF53901 13 324 2.64E-48 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_26395 0e184dbc2cfaae4100f1c78b2fafcf6b 299 PIRSF PIRSF018296 81 299 1.1E-61 T 14-10-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 TSH58p_26395 0e184dbc2cfaae4100f1c78b2fafcf6b 299 PIRSF PIRSF018296 15 92 2.0E-9 T 14-10-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 TSH58p_26395 0e184dbc2cfaae4100f1c78b2fafcf6b 299 Gene3D G3DSA:3.90.1670.10 35 299 5.4E-80 T 14-10-2018 IPR024064 FdhE-like superfamily TSH58p_26395 0e184dbc2cfaae4100f1c78b2fafcf6b 299 SUPERFAMILY SSF144020 41 296 2.62E-71 T 14-10-2018 IPR024064 FdhE-like superfamily TSH58p_26395 0e184dbc2cfaae4100f1c78b2fafcf6b 299 TIGRFAM TIGR01562 FdhE: formate dehydrogenase accessory protein FdhE 83 296 2.1E-56 T 14-10-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 TSH58p_26395 0e184dbc2cfaae4100f1c78b2fafcf6b 299 Pfam PF04216 Protein involved in formate dehydrogenase formation 34 295 2.5E-76 T 14-10-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 TSH58p_06640 8e4bc6421c1cf04319b4fcba30a9dbfd 274 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 10 269 42.285 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TSH58p_06640 8e4bc6421c1cf04319b4fcba30a9dbfd 274 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 12 269 1.1E-98 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TSH58p_06640 8e4bc6421c1cf04319b4fcba30a9dbfd 274 SUPERFAMILY SSF51621 15 269 3.19E-100 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSH58p_06640 8e4bc6421c1cf04319b4fcba30a9dbfd 274 PIRSF PIRSF000388 1 272 5.0E-103 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TSH58p_06640 8e4bc6421c1cf04319b4fcba30a9dbfd 274 Gene3D G3DSA:3.20.20.60 10 274 3.1E-104 T 14-10-2018 TSH58p_06640 8e4bc6421c1cf04319b4fcba30a9dbfd 274 Pfam PF02548 Ketopantoate hydroxymethyltransferase 10 264 9.2E-107 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TSH58p_11750 7c84df66d1d619e943a85fc3bb0bd998 69 PRINTS PR00050 Cold shock protein signature 25 34 2.8E-16 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_11750 7c84df66d1d619e943a85fc3bb0bd998 69 PRINTS PR00050 Cold shock protein signature 40 58 2.8E-16 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_11750 7c84df66d1d619e943a85fc3bb0bd998 69 PRINTS PR00050 Cold shock protein signature 4 19 2.8E-16 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_11750 7c84df66d1d619e943a85fc3bb0bd998 69 Gene3D G3DSA:2.40.50.140 1 66 3.3E-26 T 14-10-2018 TSH58p_11750 7c84df66d1d619e943a85fc3bb0bd998 69 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 7.2E-26 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_11750 7c84df66d1d619e943a85fc3bb0bd998 69 SUPERFAMILY SSF50249 1 67 5.14E-22 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_11750 7c84df66d1d619e943a85fc3bb0bd998 69 SMART SM00357 3 67 8.9E-23 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 TSH58p_11750 7c84df66d1d619e943a85fc3bb0bd998 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 14-10-2018 IPR019844 Cold-shock conserved site TSH58p_11750 7c84df66d1d619e943a85fc3bb0bd998 69 PIRSF PIRSF002599 1 69 2.3E-23 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 TSH58p_27455 7e0e9c21523102dfebf5bb652af9f871 325 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 3 312 9.0E-86 T 14-10-2018 IPR007296 Domain of unknown function DUF403 TSH58p_27045 73f5636848aea54e024be75231668fd6 99 Pfam PF07235 Protein of unknown function (DUF1427) 3 82 2.2E-34 T 14-10-2018 IPR009872 Protein of unknown function DUF1427 TSH58p_27045 73f5636848aea54e024be75231668fd6 99 TIGRFAM TIGR03510 XapX: XapX domain 3 50 1.0E-19 T 14-10-2018 IPR020017 XapX domain TSH58p_18175 3db4ad210c6023dab3a3d67136f849bf 127 SUPERFAMILY SSF48295 16 63 9.94E-9 T 14-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 TSH58p_18175 3db4ad210c6023dab3a3d67136f849bf 127 Pfam PF01527 Transposase 17 70 6.8E-15 T 14-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 TSH58p_16190 52be01dedc9e8c21dfc2db5195d43b50 188 Pfam PF09285 Elongation factor P, C-terminal 130 185 1.5E-23 T 14-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 TSH58p_16190 52be01dedc9e8c21dfc2db5195d43b50 188 Gene3D G3DSA:2.30.30.30 3 64 8.0E-19 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 TSH58p_16190 52be01dedc9e8c21dfc2db5195d43b50 188 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 5 61 3.4E-19 T 14-10-2018 IPR013185 Translation elongation factor, KOW-like TSH58p_16190 52be01dedc9e8c21dfc2db5195d43b50 188 SMART SM01185 68 122 1.7E-25 T 14-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 TSH58p_16190 52be01dedc9e8c21dfc2db5195d43b50 188 SUPERFAMILY SSF50249 66 127 1.67E-17 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_16190 52be01dedc9e8c21dfc2db5195d43b50 188 Gene3D G3DSA:2.40.50.140 65 128 1.1E-21 T 14-10-2018 TSH58p_16190 52be01dedc9e8c21dfc2db5195d43b50 188 Pfam PF01132 Elongation factor P (EF-P) OB domain 70 122 3.9E-20 T 14-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 TSH58p_16190 52be01dedc9e8c21dfc2db5195d43b50 188 ProSitePatterns PS01275 Elongation factor P signature. 151 170 - T 14-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site TSH58p_16190 52be01dedc9e8c21dfc2db5195d43b50 188 SUPERFAMILY SSF50249 130 186 7.02E-17 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_16190 52be01dedc9e8c21dfc2db5195d43b50 188 PIRSF PIRSF005901 1 187 1.8E-67 T 14-10-2018 IPR020599 Translation elongation factor P/YeiP TSH58p_16190 52be01dedc9e8c21dfc2db5195d43b50 188 SMART SM00841 130 185 2.6E-30 T 14-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 TSH58p_16190 52be01dedc9e8c21dfc2db5195d43b50 188 Hamap MF_00141 Elongation factor P [efp]. 2 186 43.607 T 14-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 TSH58p_16190 52be01dedc9e8c21dfc2db5195d43b50 188 SUPERFAMILY SSF50104 3 64 9.63E-16 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily TSH58p_16190 52be01dedc9e8c21dfc2db5195d43b50 188 TIGRFAM TIGR00038 efp: translation elongation factor P 4 186 1.2E-70 T 14-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 TSH58p_16190 52be01dedc9e8c21dfc2db5195d43b50 188 Gene3D G3DSA:2.40.50.140 130 187 2.1E-23 T 14-10-2018 TSH58p_02260 0c1321788595f88c02903efd85aec899 348 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 10 164 2.5E-34 T 14-10-2018 IPR017516 AbrB duplication TSH58p_02260 0c1321788595f88c02903efd85aec899 348 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 190 344 4.2E-39 T 14-10-2018 IPR017516 AbrB duplication TSH58p_02260 0c1321788595f88c02903efd85aec899 348 PIRSF PIRSF038991 1 348 2.2E-69 T 14-10-2018 IPR007820 AbrB family GO:0010468|GO:0016021 TSH58p_02260 0c1321788595f88c02903efd85aec899 348 Pfam PF05145 Transition state regulatory protein AbrB 34 345 1.1E-82 T 14-10-2018 IPR007820 AbrB family GO:0010468|GO:0016021 TSH58p_19895 8f5a221587cd01fbcbdef7ba0a1df399 584 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 200 327 1.1E-27 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 TSH58p_19895 8f5a221587cd01fbcbdef7ba0a1df399 584 Gene3D G3DSA:3.40.50.970 1 180 3.4E-56 T 14-10-2018 TSH58p_19895 8f5a221587cd01fbcbdef7ba0a1df399 584 Gene3D G3DSA:3.40.50.970 357 572 1.2E-59 T 14-10-2018 TSH58p_19895 8f5a221587cd01fbcbdef7ba0a1df399 584 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 169 3.3E-44 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 TSH58p_19895 8f5a221587cd01fbcbdef7ba0a1df399 584 SUPERFAMILY SSF52518 366 555 2.32E-59 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_19895 8f5a221587cd01fbcbdef7ba0a1df399 584 Gene3D G3DSA:3.40.50.1220 188 343 3.1E-41 T 14-10-2018 TSH58p_19895 8f5a221587cd01fbcbdef7ba0a1df399 584 SUPERFAMILY SSF52467 157 357 2.14E-39 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TSH58p_19895 8f5a221587cd01fbcbdef7ba0a1df399 584 SUPERFAMILY SSF52518 4 175 3.34E-46 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_19895 8f5a221587cd01fbcbdef7ba0a1df399 584 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 389 536 3.5E-38 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TSH58p_08170 7c9e9449d6f77e2576ad7f393fccc01c 468 SUPERFAMILY SSF63411 277 462 1.83E-30 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TSH58p_08170 7c9e9449d6f77e2576ad7f393fccc01c 468 Pfam PF00675 Insulinase (Peptidase family M16) 60 205 3.1E-28 T 14-10-2018 IPR011765 Peptidase M16, N-terminal TSH58p_08170 7c9e9449d6f77e2576ad7f393fccc01c 468 Gene3D G3DSA:3.30.830.10 268 463 1.4E-43 T 14-10-2018 TSH58p_08170 7c9e9449d6f77e2576ad7f393fccc01c 468 Pfam PF05193 Peptidase M16 inactive domain 214 395 2.3E-32 T 14-10-2018 IPR007863 Peptidase M16, C-terminal TSH58p_08170 7c9e9449d6f77e2576ad7f393fccc01c 468 SUPERFAMILY SSF63411 50 263 5.5E-60 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TSH58p_08170 7c9e9449d6f77e2576ad7f393fccc01c 468 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 80 103 - T 14-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 TSH58p_08170 7c9e9449d6f77e2576ad7f393fccc01c 468 Gene3D G3DSA:3.30.830.10 49 266 1.3E-75 T 14-10-2018 TSH58p_11605 e01c4b5c6a279d0828939597e9ce0141 442 Gene3D G3DSA:3.40.50.150 94 436 9.1E-81 T 14-10-2018 TSH58p_11605 e01c4b5c6a279d0828939597e9ce0141 442 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 373 403 - T 14-10-2018 IPR030390 RNA methyltransferase TrmA, active site TSH58p_11605 e01c4b5c6a279d0828939597e9ce0141 442 Gene3D G3DSA:2.40.50.140 7 93 4.8E-16 T 14-10-2018 TSH58p_11605 e01c4b5c6a279d0828939597e9ce0141 442 SUPERFAMILY SSF50249 20 80 8.57E-8 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_11605 e01c4b5c6a279d0828939597e9ce0141 442 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 366 438 1.1E-7 T 14-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 TSH58p_11605 e01c4b5c6a279d0828939597e9ce0141 442 SUPERFAMILY SSF53335 82 440 1.0E-54 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_11605 e01c4b5c6a279d0828939597e9ce0141 442 Gene3D G3DSA:3.40.1350.30 139 281 9.1E-81 T 14-10-2018 TSH58p_08800 de9dc1ad9236a56f9d0ab5c9cf75a9d5 98 Hamap MF_02117 N(2)-fixation sustaining protein CowN [cowN]. 4 98 26.215 T 14-10-2018 IPR024899 Nitrogen fixation-sustaining protein CowN GO:0009399 TSH58p_06485 edf2848164e09c28a65fe63ccc54292e 170 Pfam PF04093 rod shape-determining protein MreD 19 156 1.5E-15 T 14-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 TSH58p_06485 edf2848164e09c28a65fe63ccc54292e 170 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 16 161 6.8E-20 T 14-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 TSH58p_18290 2358acc49ea34cec3a323d59b6583005 450 Pfam PF14524 Wzt C-terminal domain 295 432 1.1E-31 T 14-10-2018 IPR029439 Wzt, C-terminal TSH58p_18290 2358acc49ea34cec3a323d59b6583005 450 Gene3D G3DSA:3.40.50.300 7 261 8.5E-44 T 14-10-2018 TSH58p_18290 2358acc49ea34cec3a323d59b6583005 450 SUPERFAMILY SSF52540 40 237 3.91E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_18290 2358acc49ea34cec3a323d59b6583005 450 Gene3D G3DSA:2.70.50.60 289 432 7.7E-18 T 14-10-2018 TSH58p_18290 2358acc49ea34cec3a323d59b6583005 450 Pfam PF00005 ABC transporter 44 175 2.0E-18 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_18290 2358acc49ea34cec3a323d59b6583005 450 SMART SM00382 52 229 5.3E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_31985 cafe17521dd1767100c422c002a033c9 409 Hamap MF_00242 Arginine deiminase [arcA]. 1 408 47.136 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 TSH58p_31985 cafe17521dd1767100c422c002a033c9 409 Pfam PF02274 Amidinotransferase 18 405 2.1E-102 T 14-10-2018 TSH58p_31985 cafe17521dd1767100c422c002a033c9 409 SUPERFAMILY SSF55909 4 407 1.16E-131 T 14-10-2018 TSH58p_31985 cafe17521dd1767100c422c002a033c9 409 PRINTS PR01466 Bacterial arginine deiminase signature 344 361 4.7E-51 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 TSH58p_31985 cafe17521dd1767100c422c002a033c9 409 PRINTS PR01466 Bacterial arginine deiminase signature 150 168 4.7E-51 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 TSH58p_31985 cafe17521dd1767100c422c002a033c9 409 PRINTS PR01466 Bacterial arginine deiminase signature 2 22 4.7E-51 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 TSH58p_31985 cafe17521dd1767100c422c002a033c9 409 PRINTS PR01466 Bacterial arginine deiminase signature 387 405 4.7E-51 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 TSH58p_31985 cafe17521dd1767100c422c002a033c9 409 PRINTS PR01466 Bacterial arginine deiminase signature 364 378 4.7E-51 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 TSH58p_31985 cafe17521dd1767100c422c002a033c9 409 PRINTS PR01466 Bacterial arginine deiminase signature 178 193 4.7E-51 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 TSH58p_31985 cafe17521dd1767100c422c002a033c9 409 Gene3D G3DSA:1.10.3930.10 68 149 5.1E-149 T 14-10-2018 TSH58p_31985 cafe17521dd1767100c422c002a033c9 409 Gene3D G3DSA:3.75.10.10 6 405 5.1E-149 T 14-10-2018 TSH58p_31985 cafe17521dd1767100c422c002a033c9 409 PIRSF PIRSF006356 1 408 4.0E-134 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 TSH58p_08280 7e5fc9b5e1c53a27ed0753a2467ae993 227 Gene3D G3DSA:1.10.357.10 77 211 1.0E-26 T 14-10-2018 TSH58p_08280 7e5fc9b5e1c53a27ed0753a2467ae993 227 ProSitePatterns PS01081 TetR-type HTH domain signature. 46 77 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site TSH58p_08280 7e5fc9b5e1c53a27ed0753a2467ae993 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 47 2.9E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_08280 7e5fc9b5e1c53a27ed0753a2467ae993 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 55 78 2.9E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_08280 7e5fc9b5e1c53a27ed0753a2467ae993 227 SUPERFAMILY SSF46689 28 91 8.03E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_08280 7e5fc9b5e1c53a27ed0753a2467ae993 227 SUPERFAMILY SSF48498 100 211 3.44E-14 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TSH58p_08280 7e5fc9b5e1c53a27ed0753a2467ae993 227 Gene3D G3DSA:1.10.10.60 31 76 1.7E-14 T 14-10-2018 TSH58p_08280 7e5fc9b5e1c53a27ed0753a2467ae993 227 Pfam PF00440 Bacterial regulatory proteins, tetR family 38 79 1.9E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_14955 3b2b0194c5dd5c3cf82b3b98b1794ceb 231 Pfam PF00005 ABC transporter 17 160 3.8E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_14955 3b2b0194c5dd5c3cf82b3b98b1794ceb 231 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 2 231 8.6E-104 T 14-10-2018 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE TSH58p_14955 3b2b0194c5dd5c3cf82b3b98b1794ceb 231 SMART SM00382 26 210 4.9E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_14955 3b2b0194c5dd5c3cf82b3b98b1794ceb 231 Gene3D G3DSA:3.40.50.300 1 230 4.7E-58 T 14-10-2018 TSH58p_14955 3b2b0194c5dd5c3cf82b3b98b1794ceb 231 SUPERFAMILY SSF52540 2 221 9.82E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_25580 b6a73490ae047db378c083423692a957 259 Pfam PF00877 NlpC/P60 family 150 242 1.7E-15 T 14-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain TSH58p_25580 b6a73490ae047db378c083423692a957 259 SUPERFAMILY SSF54001 140 247 3.14E-27 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily TSH58p_25580 b6a73490ae047db378c083423692a957 259 Gene3D G3DSA:3.90.1720.10 137 247 1.4E-24 T 14-10-2018 TSH58p_24555 fdd42e531b8534f93c4bd3a5ca6b147e 274 Pfam PF00248 Aldo/keto reductase family 14 256 2.2E-51 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain TSH58p_24555 fdd42e531b8534f93c4bd3a5ca6b147e 274 Gene3D G3DSA:3.20.20.100 1 274 6.3E-109 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TSH58p_24555 fdd42e531b8534f93c4bd3a5ca6b147e 274 PIRSF PIRSF000097 1 116 8.7E-34 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TSH58p_24555 fdd42e531b8534f93c4bd3a5ca6b147e 274 PIRSF PIRSF000097 108 268 6.6E-34 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TSH58p_24555 fdd42e531b8534f93c4bd3a5ca6b147e 274 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 37 54 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 TSH58p_24555 fdd42e531b8534f93c4bd3a5ca6b147e 274 PRINTS PR00069 Aldo-keto reductase signature 191 215 1.5E-44 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TSH58p_24555 fdd42e531b8534f93c4bd3a5ca6b147e 274 PRINTS PR00069 Aldo-keto reductase signature 120 137 1.5E-44 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TSH58p_24555 fdd42e531b8534f93c4bd3a5ca6b147e 274 PRINTS PR00069 Aldo-keto reductase signature 33 57 1.5E-44 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TSH58p_24555 fdd42e531b8534f93c4bd3a5ca6b147e 274 PRINTS PR00069 Aldo-keto reductase signature 89 107 1.5E-44 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TSH58p_24555 fdd42e531b8534f93c4bd3a5ca6b147e 274 PRINTS PR00069 Aldo-keto reductase signature 154 183 1.5E-44 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TSH58p_24555 fdd42e531b8534f93c4bd3a5ca6b147e 274 SUPERFAMILY SSF51430 4 260 7.33E-85 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TSH58p_24555 fdd42e531b8534f93c4bd3a5ca6b147e 274 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 120 137 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 TSH58p_05560 befe40dca470265bd7168b2f2a1c25f6 368 Pfam PF04055 Radical SAM superfamily 20 173 1.9E-18 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSH58p_05560 befe40dca470265bd7168b2f2a1c25f6 368 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 247 337 3.1E-10 T 14-10-2018 IPR023885 4Fe4S-binding SPASM domain TSH58p_05560 befe40dca470265bd7168b2f2a1c25f6 368 SMART SM00729 14 223 4.8E-5 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSH58p_05560 befe40dca470265bd7168b2f2a1c25f6 368 Hamap MF_00660 Coenzyme PQQ synthesis protein E [pqqE]. 1 368 166.945 T 14-10-2018 IPR011843 Coenzyme PQQ biosynthesis protein E, bacteria GO:0018189|GO:0051539 TSH58p_05560 befe40dca470265bd7168b2f2a1c25f6 368 TIGRFAM TIGR02109 PQQ_syn_pqqE: coenzyme PQQ biosynthesis enzyme PqqE 10 354 8.3E-161 T 14-10-2018 IPR011843 Coenzyme PQQ biosynthesis protein E, bacteria GO:0018189|GO:0051539 TSH58p_05560 befe40dca470265bd7168b2f2a1c25f6 368 Pfam PF13186 Iron-sulfur cluster-binding domain 244 310 3.8E-9 T 14-10-2018 IPR023885 4Fe4S-binding SPASM domain TSH58p_05560 befe40dca470265bd7168b2f2a1c25f6 368 PIRSF PIRSF037420 4 354 1.2E-105 T 14-10-2018 IPR017200 Coenzyme PQQ synthesis protein E TSH58p_05560 befe40dca470265bd7168b2f2a1c25f6 368 Pfam PF13353 4Fe-4S single cluster domain 21 89 2.1E-6 T 14-10-2018 TSH58p_05560 befe40dca470265bd7168b2f2a1c25f6 368 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 20 31 - T 14-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_05560 befe40dca470265bd7168b2f2a1c25f6 368 SUPERFAMILY SSF102114 12 319 1.96E-67 T 14-10-2018 TSH58p_05560 befe40dca470265bd7168b2f2a1c25f6 368 Gene3D G3DSA:3.20.20.70 13 302 5.0E-41 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_08670 f4cf1cfa451baaf49866182b722de9c1 252 Gene3D G3DSA:3.40.1350.60 84 240 9.0E-51 T 14-10-2018 TSH58p_08670 f4cf1cfa451baaf49866182b722de9c1 252 Pfam PF03749 Sugar fermentation stimulation protein 13 232 1.8E-72 T 14-10-2018 IPR005224 Sugar fermentation stimulation protein TSH58p_08670 f4cf1cfa451baaf49866182b722de9c1 252 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 5 229 9.7E-61 T 14-10-2018 IPR005224 Sugar fermentation stimulation protein TSH58p_08670 f4cf1cfa451baaf49866182b722de9c1 252 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 1 241 55.206 T 14-10-2018 IPR005224 Sugar fermentation stimulation protein TSH58p_08670 f4cf1cfa451baaf49866182b722de9c1 252 Gene3D G3DSA:2.40.50.580 1 74 3.2E-26 T 14-10-2018 TSH58p_09600 2293b0f94073cb9bab3f675a8a9f0ccf 185 Gene3D G3DSA:2.30.30.40 32 158 3.3E-37 T 14-10-2018 TSH58p_09600 2293b0f94073cb9bab3f675a8a9f0ccf 185 SUPERFAMILY SSF50341 24 165 1.96E-39 T 14-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 TSH58p_09600 2293b0f94073cb9bab3f675a8a9f0ccf 185 SMART SM00260 26 164 4.1E-42 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TSH58p_09600 2293b0f94073cb9bab3f675a8a9f0ccf 185 Gene3D G3DSA:2.40.50.180 49 159 3.3E-37 T 14-10-2018 TSH58p_09600 2293b0f94073cb9bab3f675a8a9f0ccf 185 Pfam PF01584 CheW-like domain 30 165 1.9E-35 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TSH58p_01485 42a45c150e7919585155115e89c8c856 307 Gene3D G3DSA:3.40.50.1980 197 302 2.9E-20 T 14-10-2018 TSH58p_01485 42a45c150e7919585155115e89c8c856 307 Gene3D G3DSA:3.40.50.1980 35 188 9.4E-33 T 14-10-2018 TSH58p_01485 42a45c150e7919585155115e89c8c856 307 SUPERFAMILY SSF53807 37 301 2.16E-62 T 14-10-2018 TSH58p_01485 42a45c150e7919585155115e89c8c856 307 PRINTS PR00691 Adhesin B signature 57 75 9.3E-7 T 14-10-2018 IPR006129 Adhesin B GO:0007155 TSH58p_01485 42a45c150e7919585155115e89c8c856 307 PRINTS PR00691 Adhesin B signature 76 95 9.3E-7 T 14-10-2018 IPR006129 Adhesin B GO:0007155 TSH58p_01485 42a45c150e7919585155115e89c8c856 307 PRINTS PR00691 Adhesin B signature 134 153 9.3E-7 T 14-10-2018 IPR006129 Adhesin B GO:0007155 TSH58p_01485 42a45c150e7919585155115e89c8c856 307 Pfam PF01297 Zinc-uptake complex component A periplasmic 37 299 4.5E-48 T 14-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 TSH58p_01485 42a45c150e7919585155115e89c8c856 307 PRINTS PR00690 Adhesin family signature 76 93 1.9E-7 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TSH58p_01485 42a45c150e7919585155115e89c8c856 307 PRINTS PR00690 Adhesin family signature 192 213 1.9E-7 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TSH58p_01485 42a45c150e7919585155115e89c8c856 307 PRINTS PR00690 Adhesin family signature 63 76 1.9E-7 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TSH58p_01485 42a45c150e7919585155115e89c8c856 307 PRINTS PR00690 Adhesin family signature 245 263 1.9E-7 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TSH58p_21475 13a9331985c8191761cf2b69cc4eb34d 51 Pfam PF17209 Hfq protein 8 50 5.7E-21 T 14-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 TSH58p_21475 13a9331985c8191761cf2b69cc4eb34d 51 Gene3D G3DSA:2.30.30.100 1 51 9.6E-22 T 14-10-2018 TSH58p_21475 13a9331985c8191761cf2b69cc4eb34d 51 SUPERFAMILY SSF50182 7 50 2.57E-16 T 14-10-2018 IPR010920 LSM domain superfamily TSH58p_21475 13a9331985c8191761cf2b69cc4eb34d 51 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 6 50 2.2E-22 T 14-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 TSH58p_31375 c1851f84ca55c4489674646ccd7882e0 135 Gene3D G3DSA:3.40.50.1010 2 129 1.7E-13 T 14-10-2018 TSH58p_31375 c1851f84ca55c4489674646ccd7882e0 135 SUPERFAMILY SSF88723 1 126 3.64E-18 T 14-10-2018 IPR029060 PIN-like domain superfamily TSH58p_31375 c1851f84ca55c4489674646ccd7882e0 135 Pfam PF01850 PIN domain 3 118 1.2E-10 T 14-10-2018 IPR002716 PIN domain TSH58p_00805 b5cc8373e43a44486d56934e3b658230 123 Pfam PF00034 Cytochrome c 25 121 1.6E-9 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_00805 b5cc8373e43a44486d56934e3b658230 123 SUPERFAMILY SSF46626 22 121 9.19E-36 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_00805 b5cc8373e43a44486d56934e3b658230 123 Gene3D G3DSA:1.10.760.10 13 122 6.7E-46 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_00805 b5cc8373e43a44486d56934e3b658230 123 PRINTS PR00604 Class IA and IB cytochrome C signature 113 121 3.8E-24 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_00805 b5cc8373e43a44486d56934e3b658230 123 PRINTS PR00604 Class IA and IB cytochrome C signature 77 93 3.8E-24 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_00805 b5cc8373e43a44486d56934e3b658230 123 PRINTS PR00604 Class IA and IB cytochrome C signature 63 73 3.8E-24 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_00805 b5cc8373e43a44486d56934e3b658230 123 PRINTS PR00604 Class IA and IB cytochrome C signature 47 62 3.8E-24 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_00805 b5cc8373e43a44486d56934e3b658230 123 PRINTS PR00604 Class IA and IB cytochrome C signature 96 106 3.8E-24 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_00805 b5cc8373e43a44486d56934e3b658230 123 PRINTS PR00604 Class IA and IB cytochrome C signature 34 41 3.8E-24 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_15625 2f1ebfc6b1b87d81e98d15c45241f2d2 407 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 394 2.0E-70 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 TSH58p_15625 2f1ebfc6b1b87d81e98d15c45241f2d2 407 SUPERFAMILY SSF53659 1 403 3.26E-157 T 14-10-2018 TSH58p_15625 2f1ebfc6b1b87d81e98d15c45241f2d2 407 PIRSF PIRSF000108 1 406 1.5E-228 T 14-10-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 TSH58p_15625 2f1ebfc6b1b87d81e98d15c45241f2d2 407 SMART SM01329 9 395 2.7E-138 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 TSH58p_15625 2f1ebfc6b1b87d81e98d15c45241f2d2 407 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 270 289 - T 14-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 TSH58p_15625 2f1ebfc6b1b87d81e98d15c45241f2d2 407 TIGRFAM TIGR00127 nadp_idh_euk: isocitrate dehydrogenase, NADP-dependent 2 404 2.2E-220 T 14-10-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 TSH58p_15625 2f1ebfc6b1b87d81e98d15c45241f2d2 407 Gene3D G3DSA:3.40.718.10 1 405 7.1E-221 T 14-10-2018 TSH58p_24885 cea006a4fcc8aa6f78ebeb58e116f1aa 375 Gene3D G3DSA:3.40.50.2000 163 337 2.1E-60 T 14-10-2018 TSH58p_24885 cea006a4fcc8aa6f78ebeb58e116f1aa 375 SUPERFAMILY SSF53756 2 352 3.14E-69 T 14-10-2018 TSH58p_24885 cea006a4fcc8aa6f78ebeb58e116f1aa 375 Gene3D G3DSA:3.40.50.2000 14 341 2.1E-60 T 14-10-2018 TSH58p_24885 cea006a4fcc8aa6f78ebeb58e116f1aa 375 Pfam PF13439 Glycosyltransferase Family 4 36 163 8.5E-7 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TSH58p_24885 cea006a4fcc8aa6f78ebeb58e116f1aa 375 Pfam PF00534 Glycosyl transferases group 1 173 332 6.6E-36 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 TSH58p_17845 5a1392e9d273e0e1c99d07c701c4362d 396 Pfam PF00535 Glycosyl transferase family 2 83 191 1.2E-20 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_17845 5a1392e9d273e0e1c99d07c701c4362d 396 SUPERFAMILY SSF53448 78 317 4.5E-46 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_17845 5a1392e9d273e0e1c99d07c701c4362d 396 Gene3D G3DSA:3.90.550.10 67 303 1.7E-42 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_19210 8ecc56980d36a00b523f6f86029a8fbd 290 SUPERFAMILY SSF46785 1 111 3.1E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_19210 8ecc56980d36a00b523f6f86029a8fbd 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 1.2E-14 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_19210 8ecc56980d36a00b523f6f86029a8fbd 290 Gene3D G3DSA:1.10.10.10 1 89 6.8E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_19210 8ecc56980d36a00b523f6f86029a8fbd 290 Gene3D G3DSA:3.40.190.290 90 288 1.6E-63 T 14-10-2018 TSH58p_19210 8ecc56980d36a00b523f6f86029a8fbd 290 Pfam PF03466 LysR substrate binding domain 87 289 2.3E-47 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_19210 8ecc56980d36a00b523f6f86029a8fbd 290 SUPERFAMILY SSF53850 86 288 9.41E-46 T 14-10-2018 TSH58p_20740 dd670adea26b29daff308387a521fd89 190 Pfam PF01478 Type IV leader peptidase family 19 116 1.2E-10 T 14-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 TSH58p_20740 dd670adea26b29daff308387a521fd89 190 Gene3D G3DSA:1.20.120.1220 13 123 3.7E-6 T 14-10-2018 TSH58p_20590 bd729f44b4350d7e4787d5a49a83340a 420 Gene3D G3DSA:3.40.50.10990 220 379 1.4E-32 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TSH58p_20590 bd729f44b4350d7e4787d5a49a83340a 420 Pfam PF12471 GTP cyclohydrolase N terminal 11 200 1.5E-81 T 14-10-2018 IPR022163 GTP cyclohydrolase N-terminal TSH58p_20590 bd729f44b4350d7e4787d5a49a83340a 420 Pfam PF00925 GTP cyclohydrolase II 232 377 2.0E-14 T 14-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TSH58p_20590 bd729f44b4350d7e4787d5a49a83340a 420 SUPERFAMILY SSF142695 205 379 5.75E-32 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TSH58p_09090 2305de087384bd5d34b3432d509ea82e 262 Gene3D G3DSA:1.10.3720.10 59 254 9.1E-25 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_09090 2305de087384bd5d34b3432d509ea82e 262 SUPERFAMILY SSF161098 62 244 1.07E-28 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_09090 2305de087384bd5d34b3432d509ea82e 262 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 249 2.5E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_21795 c4b84e4ec94ffa05e6d0a10c5be34419 259 SUPERFAMILY SSF88713 4 254 2.13E-97 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TSH58p_21795 c4b84e4ec94ffa05e6d0a10c5be34419 259 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 3 247 44.814 T 14-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 TSH58p_21795 c4b84e4ec94ffa05e6d0a10c5be34419 259 Pfam PF03746 LamB/YcsF family 5 243 7.4E-97 T 14-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 TSH58p_21795 c4b84e4ec94ffa05e6d0a10c5be34419 259 Gene3D G3DSA:3.20.20.370 3 257 6.0E-99 T 14-10-2018 TSH58p_05370 b1eccbc178597c45113d00da53fc19b5 214 Gene3D G3DSA:3.40.50.1820 3 209 8.6E-46 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_05370 b1eccbc178597c45113d00da53fc19b5 214 Pfam PF01738 Dienelactone hydrolase family 24 196 9.1E-5 T 14-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 TSH58p_05370 b1eccbc178597c45113d00da53fc19b5 214 SUPERFAMILY SSF53474 19 208 1.7E-24 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_09295 c434f45e4d2b55ec4f240fbabc077d47 210 SUPERFAMILY SSF47413 5 76 5.2E-5 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_09295 c434f45e4d2b55ec4f240fbabc077d47 210 Gene3D G3DSA:2.10.109.10 82 208 4.6E-17 T 14-10-2018 TSH58p_09295 c434f45e4d2b55ec4f240fbabc077d47 210 Pfam PF00717 Peptidase S24-like 128 195 3.5E-15 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C TSH58p_09295 c434f45e4d2b55ec4f240fbabc077d47 210 SUPERFAMILY SSF51306 85 207 3.53E-23 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily TSH58p_26655 38b5976eacb54a28bac252be6de0df3a 273 SUPERFAMILY SSF161098 8 273 1.68E-64 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_26655 38b5976eacb54a28bac252be6de0df3a 273 Gene3D G3DSA:1.10.3720.10 2 264 2.0E-57 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_26655 38b5976eacb54a28bac252be6de0df3a 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 267 9.3E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_14095 968908a0272fbefada50a1649a20585d 284 Gene3D G3DSA:3.40.50.10330 54 123 9.2E-34 T 14-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 TSH58p_14095 968908a0272fbefada50a1649a20585d 284 SUPERFAMILY SSF111331 50 277 7.85E-52 T 14-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily TSH58p_14095 968908a0272fbefada50a1649a20585d 284 Pfam PF01513 ATP-NAD kinase 58 245 2.3E-15 T 14-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 TSH58p_14095 968908a0272fbefada50a1649a20585d 284 Gene3D G3DSA:2.60.200.30 124 258 9.2E-34 T 14-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 TSH58p_14095 968908a0272fbefada50a1649a20585d 284 Hamap MF_00361 NAD kinase [nadK]. 29 284 20.651 T 14-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 TSH58p_08485 ab21c2e1ed76238a3dd0cdd55a17850e 219 Gene3D G3DSA:2.60.40.4070 101 186 1.4E-18 T 14-10-2018 TSH58p_08485 ab21c2e1ed76238a3dd0cdd55a17850e 219 Pfam PF03963 Flagellar hook capping protein - N-terminal region 7 74 1.6E-18 T 14-10-2018 IPR005648 Flagellar hook capping protein TSH58p_08485 ab21c2e1ed76238a3dd0cdd55a17850e 219 Pfam PF13861 FlgD Tudor-like domain 88 215 1.6E-8 T 14-10-2018 IPR025963 FlgD Tudor-like domain TSH58p_08485 ab21c2e1ed76238a3dd0cdd55a17850e 219 Gene3D G3DSA:2.30.30.910 93 210 1.4E-18 T 14-10-2018 TSH58p_08485 ab21c2e1ed76238a3dd0cdd55a17850e 219 Pfam PF13860 FlgD Ig-like domain 103 175 2.7E-14 T 14-10-2018 IPR025965 FlgD Ig-like domain TSH58p_13125 138d75c07728c2d36daffc953001ac57 444 Pfam PF10098 Uncharacterised protein conserved in bacteria (DUF2336) 153 435 1.8E-76 T 14-10-2018 IPR019285 Protein of unknown function DUF2336 TSH58p_13125 138d75c07728c2d36daffc953001ac57 444 Gene3D G3DSA:1.25.10.10 11 153 1.3E-12 T 14-10-2018 IPR011989 Armadillo-like helical TSH58p_13125 138d75c07728c2d36daffc953001ac57 444 SUPERFAMILY SSF48371 11 134 8.63E-8 T 14-10-2018 IPR016024 Armadillo-type fold TSH58p_23620 d0ad5a9e5c1326bf81dc24e63dd0d98d 245 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_23620 d0ad5a9e5c1326bf81dc24e63dd0d98d 245 Pfam PF00005 ABC transporter 32 173 3.3E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_23620 d0ad5a9e5c1326bf81dc24e63dd0d98d 245 SUPERFAMILY SSF52540 16 242 1.01E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_23620 d0ad5a9e5c1326bf81dc24e63dd0d98d 245 SMART SM00382 41 222 2.3E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_23620 d0ad5a9e5c1326bf81dc24e63dd0d98d 245 Gene3D G3DSA:3.40.50.300 13 245 2.2E-49 T 14-10-2018 TSH58p_11700 c58cf40a1849284a7a03e2d0cfee3a05 234 Gene3D G3DSA:3.40.50.2300 2 131 2.7E-41 T 14-10-2018 TSH58p_11700 c58cf40a1849284a7a03e2d0cfee3a05 234 SMART SM00448 7 120 2.3E-46 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_11700 c58cf40a1849284a7a03e2d0cfee3a05 234 Gene3D G3DSA:1.10.10.10 132 232 4.0E-36 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_11700 c58cf40a1849284a7a03e2d0cfee3a05 234 Pfam PF00072 Response regulator receiver domain 9 120 5.6E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_11700 c58cf40a1849284a7a03e2d0cfee3a05 234 SMART SM00862 154 229 1.3E-27 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_11700 c58cf40a1849284a7a03e2d0cfee3a05 234 SUPERFAMILY SSF52172 7 129 3.42E-45 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_11700 c58cf40a1849284a7a03e2d0cfee3a05 234 SUPERFAMILY SSF46894 130 229 1.42E-32 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_11700 c58cf40a1849284a7a03e2d0cfee3a05 234 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 8 230 4.0E-104 T 14-10-2018 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 TSH58p_11700 c58cf40a1849284a7a03e2d0cfee3a05 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 229 9.8E-28 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_27435 31448b614b102360b3ddcc6be4691f9f 365 Gene3D G3DSA:3.40.190.10 152 322 7.7E-130 T 14-10-2018 TSH58p_27435 31448b614b102360b3ddcc6be4691f9f 365 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 38 322 1.0E-63 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 TSH58p_27435 31448b614b102360b3ddcc6be4691f9f 365 Gene3D G3DSA:3.40.190.170 32 336 7.7E-130 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily TSH58p_27435 31448b614b102360b3ddcc6be4691f9f 365 PIRSF PIRSF039026 1 357 1.4E-126 T 14-10-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like TSH58p_27435 31448b614b102360b3ddcc6be4691f9f 365 SUPERFAMILY SSF53850 134 270 1.34E-5 T 14-10-2018 TSH58p_30410 acca866c71b4f7660b44a481cfb4fb89 357 Pfam PF02558 Ketopantoate reductase PanE/ApbA 7 166 8.9E-27 T 14-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain TSH58p_30410 acca866c71b4f7660b44a481cfb4fb89 357 Gene3D G3DSA:3.40.50.720 4 191 9.3E-42 T 14-10-2018 TSH58p_30410 acca866c71b4f7660b44a481cfb4fb89 357 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 6 340 4.4E-57 T 14-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 TSH58p_30410 acca866c71b4f7660b44a481cfb4fb89 357 Gene3D G3DSA:1.10.1040.10 193 341 1.1E-25 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSH58p_30410 acca866c71b4f7660b44a481cfb4fb89 357 SUPERFAMILY SSF51735 5 192 1.08E-15 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_30410 acca866c71b4f7660b44a481cfb4fb89 357 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 194 338 2.5E-23 T 14-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain TSH58p_30410 acca866c71b4f7660b44a481cfb4fb89 357 SUPERFAMILY SSF48179 191 338 1.5E-21 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_20500 7992ed0b7359dadbb592b4adaa108d4a 229 SUPERFAMILY SSF46785 12 108 2.04E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_20500 7992ed0b7359dadbb592b4adaa108d4a 229 Pfam PF07729 FCD domain 92 213 3.1E-24 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_20500 7992ed0b7359dadbb592b4adaa108d4a 229 Gene3D G3DSA:1.20.120.530 86 226 9.1E-27 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_20500 7992ed0b7359dadbb592b4adaa108d4a 229 SMART SM00895 92 216 6.6E-16 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_20500 7992ed0b7359dadbb592b4adaa108d4a 229 SMART SM00345 21 82 3.0E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_20500 7992ed0b7359dadbb592b4adaa108d4a 229 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 82 3.9E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_20500 7992ed0b7359dadbb592b4adaa108d4a 229 SUPERFAMILY SSF48008 89 223 1.65E-23 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_20500 7992ed0b7359dadbb592b4adaa108d4a 229 Gene3D G3DSA:1.10.10.10 13 83 9.6E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_20500 7992ed0b7359dadbb592b4adaa108d4a 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 6.1E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_20500 7992ed0b7359dadbb592b4adaa108d4a 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 6.1E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_28595 f81384076e6616a4ddd5f08f02a0aa33 343 Pfam PF00005 ABC transporter 33 174 2.4E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_28595 f81384076e6616a4ddd5f08f02a0aa33 343 SUPERFAMILY SSF52540 17 252 2.8E-83 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_28595 f81384076e6616a4ddd5f08f02a0aa33 343 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_28595 f81384076e6616a4ddd5f08f02a0aa33 343 SMART SM00382 41 224 1.1E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_28595 f81384076e6616a4ddd5f08f02a0aa33 343 SUPERFAMILY SSF50331 245 339 1.02E-11 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSH58p_28595 f81384076e6616a4ddd5f08f02a0aa33 343 Gene3D G3DSA:3.40.50.300 10 251 8.0E-70 T 14-10-2018 TSH58p_28595 f81384076e6616a4ddd5f08f02a0aa33 343 Pfam PF08402 TOBE domain 261 339 2.3E-12 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TSH58p_01785 584a600ff0a7070ada7d36ca23b41dca 497 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 331 458 3.1E-38 T 14-10-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain TSH58p_01785 584a600ff0a7070ada7d36ca23b41dca 497 Gene3D G3DSA:3.40.1080.20 336 477 8.2E-37 T 14-10-2018 IPR038460 Acetyl-CoA hydrolase/transferase, C-terminal domain superfamily TSH58p_01785 584a600ff0a7070ada7d36ca23b41dca 497 SUPERFAMILY SSF100950 3 222 2.06E-72 T 14-10-2018 IPR037171 NagB/RpiA transferase-like TSH58p_01785 584a600ff0a7070ada7d36ca23b41dca 497 TIGRFAM TIGR03458 YgfH_subfam: succinate CoA transferase 14 494 2.7E-224 T 14-10-2018 IPR017821 Succinate CoA transferase GO:0006084|GO:0016740 TSH58p_01785 584a600ff0a7070ada7d36ca23b41dca 497 Gene3D G3DSA:3.30.750.70 255 321 2.2E-5 T 14-10-2018 TSH58p_01785 584a600ff0a7070ada7d36ca23b41dca 497 Gene3D G3DSA:3.40.1080.10 10 176 4.6E-14 T 14-10-2018 TSH58p_01785 584a600ff0a7070ada7d36ca23b41dca 497 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 14 215 3.6E-30 T 14-10-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 TSH58p_01785 584a600ff0a7070ada7d36ca23b41dca 497 SUPERFAMILY SSF100950 229 494 1.17E-79 T 14-10-2018 IPR037171 NagB/RpiA transferase-like TSH58p_07755 d66da1f75d3e2a2bd95cb21329dafaf4 97 Gene3D G3DSA:3.30.70.20 8 91 3.9E-12 T 14-10-2018 TSH58p_07755 d66da1f75d3e2a2bd95cb21329dafaf4 97 PIRSF PIRSF036548 1 97 5.3E-44 T 14-10-2018 IPR012206 Ferredoxin-like, FixX GO:0005506 TSH58p_07755 d66da1f75d3e2a2bd95cb21329dafaf4 97 SUPERFAMILY SSF54862 12 88 1.88E-12 T 14-10-2018 TSH58p_07755 d66da1f75d3e2a2bd95cb21329dafaf4 97 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 19 95 5.7E-6 T 14-10-2018 TSH58p_00520 09775d835eb334c123325b7720490a52 155 Gene3D G3DSA:1.10.10.1550 64 119 1.7E-30 T 14-10-2018 TSH58p_00520 09775d835eb334c123325b7720490a52 155 Pfam PF05443 ROS/MUCR transcriptional regulator protein 15 136 9.2E-48 T 14-10-2018 IPR008807 ROSMUCR transcriptional regulator GO:0003677|GO:0006355|GO:0008270 TSH58p_32380 7925a73c8fdebabb047687cb3ce59024 220 SUPERFAMILY SSF161098 15 202 1.83E-43 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_32380 7925a73c8fdebabb047687cb3ce59024 220 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 210 1.2E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_32380 7925a73c8fdebabb047687cb3ce59024 220 Gene3D G3DSA:1.10.3720.10 2 219 2.0E-52 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_32380 7925a73c8fdebabb047687cb3ce59024 220 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 111 3.5E-28 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 TSH58p_13620 36643c479df066f50e08fb8e2ea79fb1 319 Gene3D G3DSA:1.10.150.130 18 116 5.3E-16 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal TSH58p_13620 36643c479df066f50e08fb8e2ea79fb1 319 SUPERFAMILY SSF56349 126 313 3.24E-48 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TSH58p_13620 36643c479df066f50e08fb8e2ea79fb1 319 SUPERFAMILY SSF47823 25 112 1.49E-10 T 14-10-2018 TSH58p_13620 36643c479df066f50e08fb8e2ea79fb1 319 Gene3D G3DSA:1.10.443.10 130 309 2.5E-49 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TSH58p_13620 36643c479df066f50e08fb8e2ea79fb1 319 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 24 105 6.4E-13 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 TSH58p_13620 36643c479df066f50e08fb8e2ea79fb1 319 Pfam PF00589 Phage integrase family 136 300 1.3E-35 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TSH58p_13620 36643c479df066f50e08fb8e2ea79fb1 319 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 19 315 50.703 T 14-10-2018 IPR023009 Tyrosine recombinase XerC/XerD TSH58p_11585 7f2a9d6e976937f002b75e1611a2ebf4 269 SUPERFAMILY SSF161098 6 261 1.83E-47 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_11585 7f2a9d6e976937f002b75e1611a2ebf4 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 260 1.2E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_11585 7f2a9d6e976937f002b75e1611a2ebf4 269 Gene3D G3DSA:1.10.3720.10 8 265 6.4E-44 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_32585 120eccae9f3cbb72f015761a87dc1c77 387 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 330 339 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 TSH58p_32585 120eccae9f3cbb72f015761a87dc1c77 387 PRINTS PR00359 B-class P450 signature 262 273 3.6E-34 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TSH58p_32585 120eccae9f3cbb72f015761a87dc1c77 387 PRINTS PR00359 B-class P450 signature 328 337 3.6E-34 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TSH58p_32585 120eccae9f3cbb72f015761a87dc1c77 387 PRINTS PR00359 B-class P450 signature 181 203 3.6E-34 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TSH58p_32585 120eccae9f3cbb72f015761a87dc1c77 387 PRINTS PR00359 B-class P450 signature 307 322 3.6E-34 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TSH58p_32585 120eccae9f3cbb72f015761a87dc1c77 387 PRINTS PR00359 B-class P450 signature 337 348 3.6E-34 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TSH58p_32585 120eccae9f3cbb72f015761a87dc1c77 387 PRINTS PR00359 B-class P450 signature 77 88 3.6E-34 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TSH58p_32585 120eccae9f3cbb72f015761a87dc1c77 387 PRINTS PR00359 B-class P450 signature 279 306 3.6E-34 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TSH58p_32585 120eccae9f3cbb72f015761a87dc1c77 387 Pfam PF00067 Cytochrome P450 26 254 1.1E-8 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TSH58p_32585 120eccae9f3cbb72f015761a87dc1c77 387 Pfam PF00067 Cytochrome P450 262 357 3.3E-14 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TSH58p_32585 120eccae9f3cbb72f015761a87dc1c77 387 SUPERFAMILY SSF48264 7 384 1.09E-84 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TSH58p_32585 120eccae9f3cbb72f015761a87dc1c77 387 Gene3D G3DSA:1.10.630.10 2 387 7.0E-112 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TSH58p_23850 786205fb9352c4ecfdb7766e0aef3872 302 SUPERFAMILY SSF55874 199 301 3.27E-15 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_23850 786205fb9352c4ecfdb7766e0aef3872 302 Gene3D G3DSA:3.30.450.20 89 161 1.1E-5 T 14-10-2018 TSH58p_23850 786205fb9352c4ecfdb7766e0aef3872 302 Pfam PF07568 Histidine kinase 109 180 2.3E-17 T 14-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain TSH58p_23850 786205fb9352c4ecfdb7766e0aef3872 302 Gene3D G3DSA:3.30.565.10 165 302 2.8E-25 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_23850 786205fb9352c4ecfdb7766e0aef3872 302 SMART SM00387 205 302 6.2E-9 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_23850 786205fb9352c4ecfdb7766e0aef3872 302 SMART SM00911 109 199 0.0091 T 14-10-2018 IPR011102 Signal transduction histidine kinase, HWE region GO:0004673 TSH58p_23850 786205fb9352c4ecfdb7766e0aef3872 302 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 208 301 7.6E-6 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_14970 672de7798b9ce8705d2d0743893f6b15 832 SMART SM00248 710 739 0.024 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 TSH58p_14970 672de7798b9ce8705d2d0743893f6b15 832 SMART SM00248 677 706 0.2 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 TSH58p_14970 672de7798b9ce8705d2d0743893f6b15 832 SMART SM00248 776 805 6.5E-5 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 TSH58p_14970 672de7798b9ce8705d2d0743893f6b15 832 SMART SM00248 743 772 1.1E-4 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 TSH58p_14970 672de7798b9ce8705d2d0743893f6b15 832 Pfam PF12796 Ankyrin repeats (3 copies) 662 741 1.0E-10 T 14-10-2018 IPR020683 Ankyrin repeat-containing domain TSH58p_14970 672de7798b9ce8705d2d0743893f6b15 832 Pfam PF12796 Ankyrin repeats (3 copies) 742 804 3.0E-12 T 14-10-2018 IPR020683 Ankyrin repeat-containing domain TSH58p_14970 672de7798b9ce8705d2d0743893f6b15 832 Gene3D G3DSA:1.25.40.20 648 832 3.5E-46 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily TSH58p_14970 672de7798b9ce8705d2d0743893f6b15 832 SUPERFAMILY SSF48403 655 831 5.57E-43 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily TSH58p_21365 63132f138eec4f4627a4b06227b00920 302 SUPERFAMILY SSF63829 3 292 7.85E-69 T 14-10-2018 TSH58p_21365 63132f138eec4f4627a4b06227b00920 302 Gene3D G3DSA:2.120.10.30 3 294 3.8E-94 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TSH58p_21365 63132f138eec4f4627a4b06227b00920 302 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 15 260 1.4E-72 T 14-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region TSH58p_21365 63132f138eec4f4627a4b06227b00920 302 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 97 118 5.1E-39 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TSH58p_21365 63132f138eec4f4627a4b06227b00920 302 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 161 181 5.1E-39 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TSH58p_21365 63132f138eec4f4627a4b06227b00920 302 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 242 260 5.1E-39 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TSH58p_21365 63132f138eec4f4627a4b06227b00920 302 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 138 160 5.1E-39 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TSH58p_21365 63132f138eec4f4627a4b06227b00920 302 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 200 217 5.1E-39 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TSH58p_21365 63132f138eec4f4627a4b06227b00920 302 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 16 33 5.1E-39 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TSH58p_18965 9f912d7846f632525165e932b6e0aa4f 234 Pfam PF07729 FCD domain 96 215 2.0E-26 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_18965 9f912d7846f632525165e932b6e0aa4f 234 Gene3D G3DSA:1.10.10.10 22 83 1.0E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_18965 9f912d7846f632525165e932b6e0aa4f 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 3.7E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_18965 9f912d7846f632525165e932b6e0aa4f 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 3.7E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_18965 9f912d7846f632525165e932b6e0aa4f 234 SMART SM00345 24 82 1.2E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_18965 9f912d7846f632525165e932b6e0aa4f 234 SUPERFAMILY SSF46785 18 86 5.64E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_18965 9f912d7846f632525165e932b6e0aa4f 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 82 6.5E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_18965 9f912d7846f632525165e932b6e0aa4f 234 SMART SM00895 92 216 1.6E-17 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_18965 9f912d7846f632525165e932b6e0aa4f 234 Gene3D G3DSA:1.20.120.530 89 228 5.5E-26 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_18965 9f912d7846f632525165e932b6e0aa4f 234 SUPERFAMILY SSF48008 92 221 5.75E-23 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_09685 e25f432c4c169a3999339af34f5589fc 985 Gene3D G3DSA:3.40.50.2300 17 169 1.9E-10 T 14-10-2018 TSH58p_09685 e25f432c4c169a3999339af34f5589fc 985 SUPERFAMILY SSF55874 366 540 3.67E-46 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_09685 e25f432c4c169a3999339af34f5589fc 985 Pfam PF00072 Response regulator receiver domain 723 836 2.9E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_09685 e25f432c4c169a3999339af34f5589fc 985 SMART SM00086 252 292 2.2E-5 T 14-10-2018 IPR001610 PAC motif TSH58p_09685 e25f432c4c169a3999339af34f5589fc 985 SUPERFAMILY SSF55785 171 290 1.1E-22 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_09685 e25f432c4c169a3999339af34f5589fc 985 Gene3D G3DSA:1.10.287.130 290 375 8.8E-27 T 14-10-2018 TSH58p_09685 e25f432c4c169a3999339af34f5589fc 985 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 177 298 1.5E-18 T 14-10-2018 IPR000014 PAS domain TSH58p_09685 e25f432c4c169a3999339af34f5589fc 985 SMART SM00448 30 153 0.057 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_09685 e25f432c4c169a3999339af34f5589fc 985 SMART SM00448 721 836 1.8E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_09685 e25f432c4c169a3999339af34f5589fc 985 Pfam PF00512 His Kinase A (phospho-acceptor) domain 312 377 1.0E-19 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_09685 e25f432c4c169a3999339af34f5589fc 985 SMART SM00387 424 544 5.6E-38 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_09685 e25f432c4c169a3999339af34f5589fc 985 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 424 542 2.4E-30 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_09685 e25f432c4c169a3999339af34f5589fc 985 Pfam PF01627 Hpt domain 890 967 2.3E-9 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TSH58p_09685 e25f432c4c169a3999339af34f5589fc 985 SUPERFAMILY SSF47226 819 970 1.18E-17 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_09685 e25f432c4c169a3999339af34f5589fc 985 Gene3D G3DSA:3.30.450.20 170 289 7.9E-23 T 14-10-2018 TSH58p_09685 e25f432c4c169a3999339af34f5589fc 985 SMART SM00091 181 247 2.1E-8 T 14-10-2018 IPR000014 PAS domain TSH58p_09685 e25f432c4c169a3999339af34f5589fc 985 PRINTS PR00344 Bacterial sensor protein C-terminal signature 528 541 4.9E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_09685 e25f432c4c169a3999339af34f5589fc 985 PRINTS PR00344 Bacterial sensor protein C-terminal signature 487 497 4.9E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_09685 e25f432c4c169a3999339af34f5589fc 985 PRINTS PR00344 Bacterial sensor protein C-terminal signature 504 522 4.9E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_09685 e25f432c4c169a3999339af34f5589fc 985 PRINTS PR00344 Bacterial sensor protein C-terminal signature 469 483 4.9E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_09685 e25f432c4c169a3999339af34f5589fc 985 SUPERFAMILY SSF52172 722 841 2.99E-32 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_09685 e25f432c4c169a3999339af34f5589fc 985 SUPERFAMILY SSF52172 29 181 1.04E-12 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_09685 e25f432c4c169a3999339af34f5589fc 985 SUPERFAMILY SSF47384 299 379 3.92E-21 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_09685 e25f432c4c169a3999339af34f5589fc 985 Gene3D G3DSA:1.20.120.160 869 978 4.0E-18 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_09685 e25f432c4c169a3999339af34f5589fc 985 Pfam PF00989 PAS fold 181 279 2.0E-11 T 14-10-2018 IPR013767 PAS fold GO:0006355 TSH58p_09685 e25f432c4c169a3999339af34f5589fc 985 Gene3D G3DSA:3.30.565.10 376 546 4.2E-51 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_09685 e25f432c4c169a3999339af34f5589fc 985 SMART SM00388 312 377 3.3E-25 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_09685 e25f432c4c169a3999339af34f5589fc 985 Gene3D G3DSA:3.40.50.2300 712 838 1.5E-33 T 14-10-2018 TSH58p_03800 917f4a9189d0b7bd045ab0955525e516 244 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 42 211 8.3E-38 T 14-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 TSH58p_03800 917f4a9189d0b7bd045ab0955525e516 244 SUPERFAMILY SSF52402 36 197 4.89E-43 T 14-10-2018 TSH58p_03800 917f4a9189d0b7bd045ab0955525e516 244 PIRSF PIRSF000857 7 240 1.5E-73 T 14-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 TSH58p_03800 917f4a9189d0b7bd045ab0955525e516 244 Gene3D G3DSA:3.40.50.620 6 243 2.1E-55 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_22870 35fd5d4770706b0674d89c056ff2fa02 342 SUPERFAMILY SSF53067 26 147 1.09E-36 T 14-10-2018 TSH58p_22870 35fd5d4770706b0674d89c056ff2fa02 342 Pfam PF02541 Ppx/GppA phosphatase family 40 335 5.2E-45 T 14-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 TSH58p_22870 35fd5d4770706b0674d89c056ff2fa02 342 SUPERFAMILY SSF53067 152 337 8.68E-36 T 14-10-2018 TSH58p_22870 35fd5d4770706b0674d89c056ff2fa02 342 Gene3D G3DSA:3.30.420.150 147 339 4.6E-49 T 14-10-2018 TSH58p_22870 35fd5d4770706b0674d89c056ff2fa02 342 Gene3D G3DSA:3.30.420.40 10 146 3.9E-41 T 14-10-2018 TSH58p_32395 576218401ba933f6b2d4b59e7daea357 376 Pfam PF01070 FMN-dependent dehydrogenase 8 369 1.4E-115 T 14-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 TSH58p_32395 576218401ba933f6b2d4b59e7daea357 376 PIRSF PIRSF000138 1 376 4.2E-116 T 14-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 TSH58p_32395 576218401ba933f6b2d4b59e7daea357 376 SUPERFAMILY SSF51395 2 370 1.52E-85 T 14-10-2018 TSH58p_32395 576218401ba933f6b2d4b59e7daea357 376 Gene3D G3DSA:3.20.20.70 1 374 1.4E-114 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_11640 fa1467ff30cdb51b04b2f47e79bf1011 509 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 54 496 5.7E-155 T 14-10-2018 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021|GO:0055114 TSH58p_11640 fa1467ff30cdb51b04b2f47e79bf1011 509 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 293 304 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_11640 fa1467ff30cdb51b04b2f47e79bf1011 509 Gene3D G3DSA:2.60.40.10 387 507 2.1E-16 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_11640 fa1467ff30cdb51b04b2f47e79bf1011 509 Pfam PF12801 4Fe-4S binding domain 115 153 1.1E-10 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_11640 fa1467ff30cdb51b04b2f47e79bf1011 509 Pfam PF13746 4Fe-4S dicluster domain 237 345 9.3E-44 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_11640 fa1467ff30cdb51b04b2f47e79bf1011 509 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 384 507 3.4E-28 T 14-10-2018 IPR032879 FixG, C-terminal immunoglobulin-like domain TSH58p_11640 fa1467ff30cdb51b04b2f47e79bf1011 509 SUPERFAMILY SSF54862 124 355 1.57E-27 T 14-10-2018 TSH58p_30940 558fb286e5f32b4b2779e940d44d5af2 629 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 49 175 4.1E-28 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ TSH58p_30940 558fb286e5f32b4b2779e940d44d5af2 629 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 218 624 5.2E-94 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TSH58p_30940 558fb286e5f32b4b2779e940d44d5af2 629 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 225 626 2.0E-82 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSH58p_24820 1232487444b6946b9bf45839310a0662 759 Gene3D G3DSA:3.40.50.300 202 354 3.6E-118 T 14-10-2018 TSH58p_24820 1232487444b6946b9bf45839310a0662 759 SMART SM00490 386 475 1.4E-16 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_24820 1232487444b6946b9bf45839310a0662 759 Pfam PF12513 Mitochondrial degradasome RNA helicase subunit C terminal 624 670 3.5E-13 T 14-10-2018 IPR022192 Mitochondrial degradasome RNA helicase subunit, C-terminal domain GO:0016817 TSH58p_24820 1232487444b6946b9bf45839310a0662 759 Pfam PF00271 Helicase conserved C-terminal domain 370 475 5.3E-12 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_24820 1232487444b6946b9bf45839310a0662 759 SUPERFAMILY SSF52540 214 486 4.71E-28 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_24820 1232487444b6946b9bf45839310a0662 759 Gene3D G3DSA:3.40.50.300 355 501 3.6E-118 T 14-10-2018 TSH58p_24820 1232487444b6946b9bf45839310a0662 759 Gene3D G3DSA:1.20.58.1080 580 678 2.8E-6 T 14-10-2018 TSH58p_24820 1232487444b6946b9bf45839310a0662 759 Gene3D G3DSA:1.20.272.40 502 573 3.6E-118 T 14-10-2018 TSH58p_17405 df4633544c942248cb05102255b9471d 360 Pfam PF03837 RecT family 49 275 2.8E-33 T 14-10-2018 IPR018330 RecT family GO:0003677|GO:0006259 TSH58p_17405 df4633544c942248cb05102255b9471d 360 TIGRFAM TIGR00616 rect: recombinase, phage RecT family 16 272 1.8E-45 T 14-10-2018 IPR004590 DNA single-strand annealing protein RecT GO:0003677|GO:0006259 TSH58p_21685 26c7a074e902ef7970276005e5c7a80b 541 Pfam PF11941 Domain of unknown function (DUF3459) 446 532 3.6E-8 T 14-10-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) TSH58p_21685 26c7a074e902ef7970276005e5c7a80b 541 SUPERFAMILY SSF51445 6 458 1.09E-114 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_21685 26c7a074e902ef7970276005e5c7a80b 541 Gene3D G3DSA:3.90.400.10 107 177 6.6E-145 T 14-10-2018 TSH58p_21685 26c7a074e902ef7970276005e5c7a80b 541 SMART SM00642 15 398 1.1E-87 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSH58p_21685 26c7a074e902ef7970276005e5c7a80b 541 Pfam PF00128 Alpha amylase, catalytic domain 30 372 2.4E-68 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSH58p_21685 26c7a074e902ef7970276005e5c7a80b 541 Gene3D G3DSA:3.20.20.80 7 453 6.6E-145 T 14-10-2018 TSH58p_21685 26c7a074e902ef7970276005e5c7a80b 541 SUPERFAMILY SSF51011 467 538 1.57E-6 T 14-10-2018 TSH58p_12550 487c633d7dbb7da90819e9167dbe8cec 173 Pfam PF06676 Protein of unknown function (DUF1178) 1 169 2.2E-54 T 14-10-2018 IPR009562 Protein of unknown function DUF1178 TSH58p_12550 487c633d7dbb7da90819e9167dbe8cec 173 PIRSF PIRSF032131 1 173 7.8E-43 T 14-10-2018 IPR009562 Protein of unknown function DUF1178 TSH58p_00955 d4dd80fcee5918e96b26e0d71e92e803 399 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 250 371 2.8E-7 T 14-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain TSH58p_00955 d4dd80fcee5918e96b26e0d71e92e803 399 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 13 102 7.8E-12 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TSH58p_00955 d4dd80fcee5918e96b26e0d71e92e803 399 PIRSF PIRSF016578 2 392 8.9E-17 T 14-10-2018 TSH58p_00955 d4dd80fcee5918e96b26e0d71e92e803 399 Gene3D G3DSA:1.20.140.10 236 385 3.7E-19 T 14-10-2018 TSH58p_00955 d4dd80fcee5918e96b26e0d71e92e803 399 SUPERFAMILY SSF56645 6 214 3.4E-33 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TSH58p_00955 d4dd80fcee5918e96b26e0d71e92e803 399 Gene3D G3DSA:2.40.110.10 137 223 7.5E-7 T 14-10-2018 TSH58p_00955 d4dd80fcee5918e96b26e0d71e92e803 399 Gene3D G3DSA:1.10.540.10 7 120 1.4E-23 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TSH58p_00955 d4dd80fcee5918e96b26e0d71e92e803 399 SUPERFAMILY SSF47203 238 381 2.86E-12 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TSH58p_24480 50193f52759a81db0c510c9da83d2167 234 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_24480 50193f52759a81db0c510c9da83d2167 234 SMART SM00382 26 213 6.8E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_24480 50193f52759a81db0c510c9da83d2167 234 SUPERFAMILY SSF52540 2 231 1.2E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_24480 50193f52759a81db0c510c9da83d2167 234 Pfam PF00005 ABC transporter 17 162 6.1E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_24480 50193f52759a81db0c510c9da83d2167 234 Gene3D G3DSA:3.40.50.300 1 234 3.2E-63 T 14-10-2018 TSH58p_16255 fd07a686d9f20ada78b7521cd8b13e4a 104 Gene3D G3DSA:1.10.20.30 1 44 8.1E-7 T 14-10-2018 TSH58p_16255 fd07a686d9f20ada78b7521cd8b13e4a 104 Pfam PF05164 Cell division protein ZapA 4 100 9.5E-18 T 14-10-2018 IPR007838 Cell division protein ZapA-like TSH58p_16255 fd07a686d9f20ada78b7521cd8b13e4a 104 SUPERFAMILY SSF102829 3 65 3.53E-15 T 14-10-2018 IPR036192 Cell division protein ZapA-like superfamily TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 237 781 5.7E-150 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 SUPERFAMILY SSF81665 263 766 8.11E-16 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 Pfam PF00122 E1-E2 ATPase 299 480 8.9E-44 T 14-10-2018 TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 SUPERFAMILY SSF55008 79 153 5.11E-18 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 Pfam PF00403 Heavy-metal-associated domain 86 145 3.7E-9 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 Gene3D G3DSA:2.70.150.20 288 403 5.4E-25 T 14-10-2018 TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 PRINTS PR00943 Copper-transporting ATPase signature 268 287 8.3E-5 T 14-10-2018 TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 PRINTS PR00943 Copper-transporting ATPase signature 422 436 8.3E-5 T 14-10-2018 TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 PRINTS PR00943 Copper-transporting ATPase signature 483 498 8.3E-5 T 14-10-2018 TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 PRINTS PR00943 Copper-transporting ATPase signature 127 147 8.3E-5 T 14-10-2018 TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 PRINTS PR00943 Copper-transporting ATPase signature 656 673 8.3E-5 T 14-10-2018 TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 Pfam PF12156 Putative metal-binding domain of cation transport ATPase 4 51 3.0E-9 T 14-10-2018 IPR021993 Putative metal-binding domain of cation transport ATPase TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 SUPERFAMILY SSF56784 498 779 2.22E-40 T 14-10-2018 IPR036412 HAD-like superfamily TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 Gene3D G3DSA:3.40.1110.10 510 611 4.7E-58 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 Pfam PF00702 haloacid dehalogenase-like hydrolase 496 692 8.2E-35 T 14-10-2018 TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 606 766 1.5E-27 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 270 512 1.3E-30 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 262 782 5.0E-103 T 14-10-2018 TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 679 698 6.4E-17 T 14-10-2018 TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 500 514 6.4E-17 T 14-10-2018 TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 604 615 6.4E-17 T 14-10-2018 TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 349 363 6.4E-17 T 14-10-2018 TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 626 636 6.4E-17 T 14-10-2018 TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 702 714 6.4E-17 T 14-10-2018 TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 220 781 6.1E-148 T 14-10-2018 TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 Gene3D G3DSA:3.30.70.100 80 150 1.2E-14 T 14-10-2018 TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 SUPERFAMILY SSF81653 307 399 5.36E-18 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 Gene3D G3DSA:3.40.50.1000 480 715 4.7E-58 T 14-10-2018 IPR023214 HAD superfamily TSH58p_11650 2604c291808f9e2d2795060c700d577c 822 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 502 508 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 TSH58p_07635 688783bbee59593451d7939878859995 293 PIRSF PIRSF000363 2 278 1.3E-120 T 14-10-2018 IPR000392 NifH/frxC family GO:0005524|GO:0016491|GO:0055114 TSH58p_07635 688783bbee59593451d7939878859995 293 SUPERFAMILY SSF52540 4 279 2.83E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_07635 688783bbee59593451d7939878859995 293 Pfam PF00142 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family 4 275 1.3E-134 T 14-10-2018 IPR000392 NifH/frxC family GO:0005524|GO:0016491|GO:0055114 TSH58p_07635 688783bbee59593451d7939878859995 293 ProSitePatterns PS00746 NifH/frxC family signature 1. 88 100 - T 14-10-2018 IPR030655 NifH/chlL conserved site TSH58p_07635 688783bbee59593451d7939878859995 293 Gene3D G3DSA:3.40.50.300 2 277 1.0E-66 T 14-10-2018 TSH58p_07635 688783bbee59593451d7939878859995 293 Hamap MF_00533 Nitrogenase iron protein [nifH]. 3 276 52.876 T 14-10-2018 IPR005977 Nitrogenase iron protein NifH GO:0009399|GO:0016163|GO:0016612|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 TSH58p_07635 688783bbee59593451d7939878859995 293 TIGRFAM TIGR01287 nifH: nitrogenase iron protein 4 278 9.7E-139 T 14-10-2018 IPR005977 Nitrogenase iron protein NifH GO:0009399|GO:0016163|GO:0016612|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 TSH58p_07635 688783bbee59593451d7939878859995 293 PRINTS PR00091 Nitrogenase component II signature 86 100 6.8E-37 T 14-10-2018 TSH58p_07635 688783bbee59593451d7939878859995 293 PRINTS PR00091 Nitrogenase component II signature 124 139 6.8E-37 T 14-10-2018 TSH58p_07635 688783bbee59593451d7939878859995 293 PRINTS PR00091 Nitrogenase component II signature 9 22 6.8E-37 T 14-10-2018 TSH58p_07635 688783bbee59593451d7939878859995 293 PRINTS PR00091 Nitrogenase component II signature 31 46 6.8E-37 T 14-10-2018 TSH58p_07635 688783bbee59593451d7939878859995 293 ProSitePatterns PS00692 NifH/frxC family signature 2. 125 138 - T 14-10-2018 IPR030655 NifH/chlL conserved site TSH58p_01200 a2962883ede05d4ce57fef2a5a7c0ac9 370 Gene3D G3DSA:3.30.470.20 171 262 1.5E-10 T 14-10-2018 TSH58p_01200 a2962883ede05d4ce57fef2a5a7c0ac9 370 SUPERFAMILY SSF56059 113 355 2.05E-18 T 14-10-2018 TSH58p_01200 a2962883ede05d4ce57fef2a5a7c0ac9 370 Pfam PF02655 ATP-grasp domain 111 263 2.8E-14 T 14-10-2018 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 TSH58p_01200 a2962883ede05d4ce57fef2a5a7c0ac9 370 Gene3D G3DSA:3.30.1490.350 137 170 1.5E-10 T 14-10-2018 TSH58p_01200 a2962883ede05d4ce57fef2a5a7c0ac9 370 PIRSF PIRSF016817 1 370 1.3E-87 T 14-10-2018 IPR016677 Uncharacterised conserved protein UCP016817, ATP-dependent carboligase TSH58p_15175 add48225bd62769f63f7f08df7b82822 105 Gene3D G3DSA:3.30.70.330 8 105 1.9E-34 T 14-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TSH58p_15175 add48225bd62769f63f7f08df7b82822 105 ProSitePatterns PS00050 Ribosomal protein L23 signature. 87 102 - T 14-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15175 add48225bd62769f63f7f08df7b82822 105 Pfam PF00276 Ribosomal protein L23 16 101 7.2E-34 T 14-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 TSH58p_15175 add48225bd62769f63f7f08df7b82822 105 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 15 104 22.558 T 14-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 TSH58p_15175 add48225bd62769f63f7f08df7b82822 105 SUPERFAMILY SSF54189 14 103 9.35E-34 T 14-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_26285 8a36a05c50fec0e6d0c63486fb236788 307 PIRSF PIRSF005052 20 304 3.2E-96 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 TSH58p_26285 8a36a05c50fec0e6d0c63486fb236788 307 SUPERFAMILY SSF52540 20 168 7.35E-12 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_26285 8a36a05c50fec0e6d0c63486fb236788 307 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 20 301 39.917 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 TSH58p_26285 8a36a05c50fec0e6d0c63486fb236788 307 Gene3D G3DSA:3.40.50.300 45 171 2.2E-6 T 14-10-2018 TSH58p_26285 8a36a05c50fec0e6d0c63486fb236788 307 Pfam PF03668 P-loop ATPase protein family 21 302 1.9E-89 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 TSH58p_01115 c41c0140eda520640ef0864c41a97f27 218 SUPERFAMILY SSF53633 6 142 5.45E-11 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSH58p_01115 c41c0140eda520640ef0864c41a97f27 218 Gene3D G3DSA:3.40.1160.10 2 146 2.4E-17 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSH58p_01115 c41c0140eda520640ef0864c41a97f27 218 Pfam PF00696 Amino acid kinase family 6 65 4.2E-6 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TSH58p_11695 443427d8b0d643232fe00007bdfcf1a6 266 Pfam PF01895 PhoU domain 124 208 1.4E-20 T 14-10-2018 IPR026022 PhoU domain TSH58p_11695 443427d8b0d643232fe00007bdfcf1a6 266 Pfam PF01895 PhoU domain 21 108 3.4E-23 T 14-10-2018 IPR026022 PhoU domain TSH58p_11695 443427d8b0d643232fe00007bdfcf1a6 266 SUPERFAMILY SSF109755 8 226 1.78E-72 T 14-10-2018 TSH58p_11695 443427d8b0d643232fe00007bdfcf1a6 266 Gene3D G3DSA:1.20.58.220 113 227 1.2E-37 T 14-10-2018 IPR038078 PhoU-like domain superfamily TSH58p_11695 443427d8b0d643232fe00007bdfcf1a6 266 Gene3D G3DSA:1.20.58.220 1 112 9.9E-39 T 14-10-2018 IPR038078 PhoU-like domain superfamily TSH58p_11695 443427d8b0d643232fe00007bdfcf1a6 266 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 9 216 1.3E-70 T 14-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 TSH58p_11695 443427d8b0d643232fe00007bdfcf1a6 266 PIRSF PIRSF003107 3 222 5.0E-69 T 14-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 TSH58p_15250 e392964dd33011e76cb14ec34213ebb1 193 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 23 177 1.6E-63 T 14-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 TSH58p_15250 e392964dd33011e76cb14ec34213ebb1 193 Pfam PF00333 Ribosomal protein S5, N-terminal domain 25 89 2.7E-27 T 14-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 TSH58p_15250 e392964dd33011e76cb14ec34213ebb1 193 Pfam PF03719 Ribosomal protein S5, C-terminal domain 102 172 1.2E-30 T 14-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 TSH58p_15250 e392964dd33011e76cb14ec34213ebb1 193 SUPERFAMILY SSF54211 94 173 8.34E-25 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSH58p_15250 e392964dd33011e76cb14ec34213ebb1 193 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 178 35.966 T 14-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 TSH58p_15250 e392964dd33011e76cb14ec34213ebb1 193 Gene3D G3DSA:3.30.160.20 17 87 2.1E-29 T 14-10-2018 TSH58p_15250 e392964dd33011e76cb14ec34213ebb1 193 SUPERFAMILY SSF54768 22 90 2.3E-22 T 14-10-2018 TSH58p_15250 e392964dd33011e76cb14ec34213ebb1 193 ProSitePatterns PS00585 Ribosomal protein S5 signature. 42 74 - T 14-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site TSH58p_15250 e392964dd33011e76cb14ec34213ebb1 193 Gene3D G3DSA:3.30.230.10 90 182 2.3E-33 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSH58p_15620 d860149a1a59f30d1a990d7316ef180d 126 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 12 87 6.5E-5 T 14-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 TSH58p_15620 d860149a1a59f30d1a990d7316ef180d 126 SUPERFAMILY SSF51735 6 93 2.35E-15 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_15620 d860149a1a59f30d1a990d7316ef180d 126 Gene3D G3DSA:3.40.50.720 2 99 2.5E-9 T 14-10-2018 TSH58p_04555 5ed9ba25e27636bf79ad5dd85ee51625 264 Pfam PF13672 Protein phosphatase 2C 19 217 4.1E-14 T 14-10-2018 TSH58p_04555 5ed9ba25e27636bf79ad5dd85ee51625 264 SUPERFAMILY SSF81606 11 259 6.8E-56 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSH58p_04555 5ed9ba25e27636bf79ad5dd85ee51625 264 Gene3D G3DSA:3.60.40.10 2 260 8.6E-60 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSH58p_04555 5ed9ba25e27636bf79ad5dd85ee51625 264 SMART SM00331 14 259 1.8E-26 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSH58p_04555 5ed9ba25e27636bf79ad5dd85ee51625 264 SMART SM00332 5 257 4.9E-23 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSH58p_09550 d00934bdcdc71a279e27019e91acd4df 190 TIGRFAM TIGR00997 ispZ: intracellular septation protein A 7 179 1.2E-50 T 14-10-2018 IPR006008 Intracellular septation protein A GO:0016021 TSH58p_09550 d00934bdcdc71a279e27019e91acd4df 190 Pfam PF04279 Intracellular septation protein A 6 176 4.7E-55 T 14-10-2018 IPR006008 Intracellular septation protein A GO:0016021 TSH58p_09550 d00934bdcdc71a279e27019e91acd4df 190 Hamap MF_00189 Probable intracellular septation protein A [yciB]. 5 179 17.726 T 14-10-2018 IPR006008 Intracellular septation protein A GO:0016021 TSH58p_24365 3aa8e523bf82df59f1e6055946999d72 370 Pfam PF02607 B12 binding domain 152 224 2.1E-13 T 14-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSH58p_24365 3aa8e523bf82df59f1e6055946999d72 370 SUPERFAMILY SSF52242 218 359 3.66E-28 T 14-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 TSH58p_24365 3aa8e523bf82df59f1e6055946999d72 370 Gene3D G3DSA:1.10.1240.10 150 226 3.8E-16 T 14-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSH58p_24365 3aa8e523bf82df59f1e6055946999d72 370 Gene3D G3DSA:3.40.50.280 230 359 1.2E-34 T 14-10-2018 TSH58p_24365 3aa8e523bf82df59f1e6055946999d72 370 SUPERFAMILY SSF46458 17 123 2.07E-5 T 14-10-2018 IPR009050 Globin-like superfamily TSH58p_24365 3aa8e523bf82df59f1e6055946999d72 370 Pfam PF02310 B12 binding domain 238 351 5.7E-18 T 14-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 TSH58p_30680 dd87a6b97ed7d7ca4bf3b0418828e701 290 Pfam PF01614 Bacterial transcriptional regulator 144 267 5.3E-8 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal TSH58p_30680 dd87a6b97ed7d7ca4bf3b0418828e701 290 Pfam PF09339 IclR helix-turn-helix domain 27 77 9.7E-14 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TSH58p_30680 dd87a6b97ed7d7ca4bf3b0418828e701 290 Gene3D G3DSA:1.10.10.10 11 93 4.0E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_30680 dd87a6b97ed7d7ca4bf3b0418828e701 290 SUPERFAMILY SSF55781 92 270 1.7E-29 T 14-10-2018 TSH58p_30680 dd87a6b97ed7d7ca4bf3b0418828e701 290 SMART SM00346 25 115 6.0E-16 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TSH58p_30680 dd87a6b97ed7d7ca4bf3b0418828e701 290 Gene3D G3DSA:3.30.450.40 101 268 3.9E-27 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_30680 dd87a6b97ed7d7ca4bf3b0418828e701 290 SUPERFAMILY SSF46785 25 98 4.05E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_15855 dc4aca7a8578e690b8c63c6f016300ea 1018 SMART SM00138 239 500 1.3E-82 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_15855 dc4aca7a8578e690b8c63c6f016300ea 1018 PRINTS PR00996 Glutamate methyltransferase family signature 338 358 2.3E-24 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_15855 dc4aca7a8578e690b8c63c6f016300ea 1018 PRINTS PR00996 Glutamate methyltransferase family signature 374 390 2.3E-24 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_15855 dc4aca7a8578e690b8c63c6f016300ea 1018 PRINTS PR00996 Glutamate methyltransferase family signature 298 310 2.3E-24 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_15855 dc4aca7a8578e690b8c63c6f016300ea 1018 PRINTS PR00996 Glutamate methyltransferase family signature 261 274 2.3E-24 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_15855 dc4aca7a8578e690b8c63c6f016300ea 1018 PRINTS PR00996 Glutamate methyltransferase family signature 440 454 2.3E-24 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_15855 dc4aca7a8578e690b8c63c6f016300ea 1018 PRINTS PR00996 Glutamate methyltransferase family signature 459 482 2.3E-24 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_15855 dc4aca7a8578e690b8c63c6f016300ea 1018 SUPERFAMILY SSF53335 305 492 9.32E-46 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_15855 dc4aca7a8578e690b8c63c6f016300ea 1018 SUPERFAMILY SSF47757 234 307 1.57E-13 T 14-10-2018 TSH58p_15855 dc4aca7a8578e690b8c63c6f016300ea 1018 SUPERFAMILY SSF52738 37 221 1.29E-56 T 14-10-2018 IPR035909 Methylesterase CheB, C-terminal TSH58p_15855 dc4aca7a8578e690b8c63c6f016300ea 1018 Gene3D G3DSA:3.40.50.180 34 224 5.0E-64 T 14-10-2018 IPR035909 Methylesterase CheB, C-terminal TSH58p_15855 dc4aca7a8578e690b8c63c6f016300ea 1018 Pfam PF08448 PAS fold 867 985 1.3E-6 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_15855 dc4aca7a8578e690b8c63c6f016300ea 1018 Gene3D G3DSA:3.40.50.150 304 501 2.0E-61 T 14-10-2018 TSH58p_15855 dc4aca7a8578e690b8c63c6f016300ea 1018 Gene3D G3DSA:3.30.450.20 861 994 1.3E-11 T 14-10-2018 TSH58p_15855 dc4aca7a8578e690b8c63c6f016300ea 1018 Gene3D G3DSA:3.30.450.20 731 860 1.9E-15 T 14-10-2018 TSH58p_15855 dc4aca7a8578e690b8c63c6f016300ea 1018 SUPERFAMILY SSF55785 857 982 6.81E-9 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_15855 dc4aca7a8578e690b8c63c6f016300ea 1018 Pfam PF01339 CheB methylesterase 41 216 3.4E-55 T 14-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 TSH58p_15855 dc4aca7a8578e690b8c63c6f016300ea 1018 Pfam PF01739 CheR methyltransferase, SAM binding domain 306 495 2.6E-54 T 14-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal TSH58p_15855 dc4aca7a8578e690b8c63c6f016300ea 1018 SUPERFAMILY SSF55785 734 854 2.09E-9 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_15855 dc4aca7a8578e690b8c63c6f016300ea 1018 Pfam PF13596 PAS domain 749 854 2.5E-24 T 14-10-2018 TSH58p_15855 dc4aca7a8578e690b8c63c6f016300ea 1018 Pfam PF03705 CheR methyltransferase, all-alpha domain 243 291 8.3E-14 T 14-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal TSH58p_02910 45467d8b8b264730eeb680d792d113a2 503 Pfam PF12706 Beta-lactamase superfamily domain 67 203 1.4E-11 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_02910 45467d8b8b264730eeb680d792d113a2 503 Gene3D G3DSA:3.40.50.10710 242 391 1.6E-153 T 14-10-2018 TSH58p_02910 45467d8b8b264730eeb680d792d113a2 503 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 397 441 2.3E-7 T 14-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain TSH58p_02910 45467d8b8b264730eeb680d792d113a2 503 Gene3D G3DSA:3.60.15.10 45 470 1.6E-153 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_02910 45467d8b8b264730eeb680d792d113a2 503 SUPERFAMILY SSF56281 45 456 9.6E-81 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_02910 45467d8b8b264730eeb680d792d113a2 503 SMART SM00849 55 257 1.7E-23 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_28505 8414f154c69c6e4074f7751913e2c62c 659 Gene3D G3DSA:1.20.1480.50 150 242 5.4E-9 T 14-10-2018 TSH58p_28505 8414f154c69c6e4074f7751913e2c62c 659 SUPERFAMILY SSF103473 259 648 9.55E-56 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_28505 8414f154c69c6e4074f7751913e2c62c 659 Pfam PF07690 Major Facilitator Superfamily 259 491 5.5E-26 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_28505 8414f154c69c6e4074f7751913e2c62c 659 Gene3D G3DSA:1.20.1250.20 252 642 1.1E-53 T 14-10-2018 TSH58p_28505 8414f154c69c6e4074f7751913e2c62c 659 Pfam PF00672 HAMP domain 186 234 2.0E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_28505 8414f154c69c6e4074f7751913e2c62c 659 SUPERFAMILY SSF158472 186 234 1.31E-7 T 14-10-2018 TSH58p_28505 8414f154c69c6e4074f7751913e2c62c 659 SMART SM00304 185 237 6.6E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_05130 396b2b98578e33aa39a760f3345dd754 432 SUPERFAMILY SSF103473 11 414 1.44E-51 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_05130 396b2b98578e33aa39a760f3345dd754 432 Gene3D G3DSA:1.20.1250.20 12 416 2.6E-48 T 14-10-2018 TSH58p_05130 396b2b98578e33aa39a760f3345dd754 432 TIGRFAM TIGR04259 oxa_formateAnti: oxalate/formate antiporter 15 418 2.9E-197 T 14-10-2018 IPR026355 Oxalate/formate antiporter GO:0016021|GO:0019531|GO:0019532 TSH58p_05130 396b2b98578e33aa39a760f3345dd754 432 Pfam PF07690 Major Facilitator Superfamily 24 271 2.9E-22 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_06095 6c8d1b92c11e89c8fd41e608f12d42b4 183 SUPERFAMILY SSF55811 8 141 4.34E-8 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TSH58p_06095 6c8d1b92c11e89c8fd41e608f12d42b4 183 Gene3D G3DSA:3.90.79.10 2 147 1.1E-6 T 14-10-2018 TSH58p_19375 244d0d8ad5842bdf8b12aaee650dc959 327 SUPERFAMILY SSF48179 199 321 5.78E-29 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_19375 244d0d8ad5842bdf8b12aaee650dc959 327 SUPERFAMILY SSF51735 1 187 1.75E-13 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_19375 244d0d8ad5842bdf8b12aaee650dc959 327 Gene3D G3DSA:3.40.50.720 1 197 3.8E-58 T 14-10-2018 TSH58p_19375 244d0d8ad5842bdf8b12aaee650dc959 327 Gene3D G3DSA:1.10.1040.10 199 326 1.7E-38 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSH58p_19375 244d0d8ad5842bdf8b12aaee650dc959 327 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 199 320 1.6E-28 T 14-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain TSH58p_19375 244d0d8ad5842bdf8b12aaee650dc959 327 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 105 2.4E-20 T 14-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain TSH58p_00250 b9e40cc7c16a3d72de23ad57142ffddb 228 SMART SM00116 10 58 3.1E-12 T 14-10-2018 IPR000644 CBS domain TSH58p_00250 b9e40cc7c16a3d72de23ad57142ffddb 228 SMART SM00116 97 144 1.7E-7 T 14-10-2018 IPR000644 CBS domain TSH58p_00250 b9e40cc7c16a3d72de23ad57142ffddb 228 Pfam PF04972 BON domain 158 221 1.6E-12 T 14-10-2018 IPR007055 BON domain TSH58p_00250 b9e40cc7c16a3d72de23ad57142ffddb 228 SUPERFAMILY SSF54631 1 142 4.42E-35 T 14-10-2018 TSH58p_00250 b9e40cc7c16a3d72de23ad57142ffddb 228 PIRSF PIRSF036990 1 227 3.1E-73 T 14-10-2018 IPR017080 Uncharacterised conserved protein UCP036990, CBS, BON TSH58p_00250 b9e40cc7c16a3d72de23ad57142ffddb 228 SMART SM00749 162 225 3.3E-4 T 14-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria TSH58p_00250 b9e40cc7c16a3d72de23ad57142ffddb 228 Gene3D G3DSA:3.10.580.10 1 151 4.4E-39 T 14-10-2018 TSH58p_00250 b9e40cc7c16a3d72de23ad57142ffddb 228 Pfam PF00571 CBS domain 90 143 1.0E-12 T 14-10-2018 IPR000644 CBS domain TSH58p_00250 b9e40cc7c16a3d72de23ad57142ffddb 228 Pfam PF00571 CBS domain 3 57 1.6E-15 T 14-10-2018 IPR000644 CBS domain TSH58p_17960 58e6760b3a9cab94ac7fdd069e2c7ba4 684 SUPERFAMILY SSF53474 311 607 2.88E-38 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_17960 58e6760b3a9cab94ac7fdd069e2c7ba4 684 Pfam PF07167 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus 186 360 2.0E-58 T 14-10-2018 IPR010941 Poly-beta-hydroxybutyrate polymerase, N-terminal domain GO:0042619 TSH58p_17960 58e6760b3a9cab94ac7fdd069e2c7ba4 684 TIGRFAM TIGR01838 PHA_synth_I: poly(R)-hydroxyalkanoic acid synthase, class I 143 682 4.0E-191 T 14-10-2018 IPR010963 Poly(R)-hydroxyalkanoic acid synthase, class I GO:0005737|GO:0016746|GO:0042619 TSH58p_17960 58e6760b3a9cab94ac7fdd069e2c7ba4 684 Gene3D G3DSA:3.40.50.1820 327 608 6.6E-10 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_00895 f08b97bddc11c3861d0bbc08efbc93bb 445 Gene3D G3DSA:2.40.30.170 199 209 3.0E-9 T 14-10-2018 TSH58p_00895 f08b97bddc11c3861d0bbc08efbc93bb 445 Gene3D G3DSA:2.40.30.170 345 423 4.0E-7 T 14-10-2018 TSH58p_00895 f08b97bddc11c3861d0bbc08efbc93bb 445 Gene3D G3DSA:2.40.50.100 210 243 3.0E-9 T 14-10-2018 TSH58p_00895 f08b97bddc11c3861d0bbc08efbc93bb 445 Gene3D G3DSA:2.40.50.100 308 343 4.0E-7 T 14-10-2018 TSH58p_00895 f08b97bddc11c3861d0bbc08efbc93bb 445 Pfam PF13437 HlyD family secretion protein 307 410 1.2E-10 T 14-10-2018 TSH58p_00895 f08b97bddc11c3861d0bbc08efbc93bb 445 Gene3D G3DSA:1.10.287.470 279 307 4.0E-7 T 14-10-2018 TSH58p_00895 f08b97bddc11c3861d0bbc08efbc93bb 445 Gene3D G3DSA:1.10.287.470 244 269 3.0E-9 T 14-10-2018 TSH58p_00895 f08b97bddc11c3861d0bbc08efbc93bb 445 SUPERFAMILY SSF111369 205 379 1.44E-8 T 14-10-2018 TSH58p_08735 37a74f7e4f5cc25ed8f85396c8ebec47 298 Pfam PF03466 LysR substrate binding domain 91 290 5.4E-34 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_08735 37a74f7e4f5cc25ed8f85396c8ebec47 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 1.4E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_08735 37a74f7e4f5cc25ed8f85396c8ebec47 298 Gene3D G3DSA:3.40.190.10 103 286 4.0E-45 T 14-10-2018 TSH58p_08735 37a74f7e4f5cc25ed8f85396c8ebec47 298 SUPERFAMILY SSF53850 93 292 1.99E-33 T 14-10-2018 TSH58p_08735 37a74f7e4f5cc25ed8f85396c8ebec47 298 Gene3D G3DSA:3.40.190.10 162 261 4.0E-45 T 14-10-2018 TSH58p_08735 37a74f7e4f5cc25ed8f85396c8ebec47 298 Gene3D G3DSA:1.10.10.10 7 89 1.1E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_08735 37a74f7e4f5cc25ed8f85396c8ebec47 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 5.5E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_08735 37a74f7e4f5cc25ed8f85396c8ebec47 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 5.5E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_08735 37a74f7e4f5cc25ed8f85396c8ebec47 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 5.5E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_08735 37a74f7e4f5cc25ed8f85396c8ebec47 298 SUPERFAMILY SSF46785 4 86 5.76E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_05305 2739225e603321055dafe00d7589ca94 156 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 22 135 3.7E-11 T 14-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 TSH58p_05305 2739225e603321055dafe00d7589ca94 156 Gene3D G3DSA:3.10.129.10 7 141 1.9E-49 T 14-10-2018 TSH58p_05305 2739225e603321055dafe00d7589ca94 156 SUPERFAMILY SSF54637 6 137 3.2E-27 T 14-10-2018 IPR029069 HotDog domain superfamily TSH58p_05305 2739225e603321055dafe00d7589ca94 156 Pfam PF03061 Thioesterase superfamily 51 126 1.1E-9 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TSH58p_08380 873bb8fa8a3bb7736cdd03887f72331a 1041 Gene3D G3DSA:3.30.70.1430 553 651 9.3E-249 T 14-10-2018 TSH58p_08380 873bb8fa8a3bb7736cdd03887f72331a 1041 Gene3D G3DSA:3.30.2090.10 182 271 9.3E-249 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_08380 873bb8fa8a3bb7736cdd03887f72331a 1041 Gene3D G3DSA:3.30.70.1320 139 329 9.3E-249 T 14-10-2018 TSH58p_08380 873bb8fa8a3bb7736cdd03887f72331a 1041 SUPERFAMILY SSF82866 788 1011 2.62E-45 T 14-10-2018 TSH58p_08380 873bb8fa8a3bb7736cdd03887f72331a 1041 SUPERFAMILY SSF82714 188 268 1.7E-10 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_08380 873bb8fa8a3bb7736cdd03887f72331a 1041 SUPERFAMILY SSF82714 705 789 6.8E-17 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_08380 873bb8fa8a3bb7736cdd03887f72331a 1041 Gene3D G3DSA:1.20.1640.10 510 1003 9.3E-249 T 14-10-2018 TSH58p_08380 873bb8fa8a3bb7736cdd03887f72331a 1041 SUPERFAMILY SSF82693 140 327 2.27E-20 T 14-10-2018 TSH58p_08380 873bb8fa8a3bb7736cdd03887f72331a 1041 Pfam PF00873 AcrB/AcrD/AcrF family 7 1004 6.0E-166 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_08380 873bb8fa8a3bb7736cdd03887f72331a 1041 Gene3D G3DSA:3.30.70.1440 652 851 9.3E-249 T 14-10-2018 TSH58p_08380 873bb8fa8a3bb7736cdd03887f72331a 1041 PRINTS PR00702 Acriflavin resistance protein family signature 440 463 9.1E-22 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_08380 873bb8fa8a3bb7736cdd03887f72331a 1041 PRINTS PR00702 Acriflavin resistance protein family signature 465 488 9.1E-22 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_08380 873bb8fa8a3bb7736cdd03887f72331a 1041 PRINTS PR00702 Acriflavin resistance protein family signature 333 356 9.1E-22 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_08380 873bb8fa8a3bb7736cdd03887f72331a 1041 PRINTS PR00702 Acriflavin resistance protein family signature 13 37 9.1E-22 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_08380 873bb8fa8a3bb7736cdd03887f72331a 1041 PRINTS PR00702 Acriflavin resistance protein family signature 387 411 9.1E-22 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_08380 873bb8fa8a3bb7736cdd03887f72331a 1041 PRINTS PR00702 Acriflavin resistance protein family signature 41 59 9.1E-22 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_08380 873bb8fa8a3bb7736cdd03887f72331a 1041 Gene3D G3DSA:3.30.70.1430 43 799 9.3E-249 T 14-10-2018 TSH58p_08380 873bb8fa8a3bb7736cdd03887f72331a 1041 SUPERFAMILY SSF82693 552 630 3.66E-6 T 14-10-2018 TSH58p_08380 873bb8fa8a3bb7736cdd03887f72331a 1041 SUPERFAMILY SSF82693 43 139 5.23E-19 T 14-10-2018 TSH58p_08380 873bb8fa8a3bb7736cdd03887f72331a 1041 Gene3D G3DSA:1.20.1640.10 13 509 9.3E-249 T 14-10-2018 TSH58p_08380 873bb8fa8a3bb7736cdd03887f72331a 1041 SUPERFAMILY SSF82866 295 487 8.24E-32 T 14-10-2018 TSH58p_08380 873bb8fa8a3bb7736cdd03887f72331a 1041 Gene3D G3DSA:3.30.2090.10 703 791 9.3E-249 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_26390 3335fb61c0253b3279619500083aca79 707 SUPERFAMILY SSF47384 454 523 6.08E-12 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_26390 3335fb61c0253b3279619500083aca79 707 SUPERFAMILY SSF55874 517 684 1.07E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_26390 3335fb61c0253b3279619500083aca79 707 SMART SM00304 364 417 1.2E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_26390 3335fb61c0253b3279619500083aca79 707 SUPERFAMILY SSF158472 364 412 1.03E-7 T 14-10-2018 TSH58p_26390 3335fb61c0253b3279619500083aca79 707 SMART SM00388 459 526 1.1E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_26390 3335fb61c0253b3279619500083aca79 707 Pfam PF00672 HAMP domain 364 412 6.0E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_26390 3335fb61c0253b3279619500083aca79 707 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 572 684 1.9E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_26390 3335fb61c0253b3279619500083aca79 707 Gene3D G3DSA:3.30.565.10 529 692 6.5E-41 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_26390 3335fb61c0253b3279619500083aca79 707 SMART SM00387 569 687 8.8E-33 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_26390 3335fb61c0253b3279619500083aca79 707 Pfam PF00512 His Kinase A (phospho-acceptor) domain 461 523 1.2E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_26390 3335fb61c0253b3279619500083aca79 707 Pfam PF17202 Single cache domain 3 226 337 7.0E-29 T 14-10-2018 IPR033463 Single cache domain 3 TSH58p_26390 3335fb61c0253b3279619500083aca79 707 PRINTS PR00344 Bacterial sensor protein C-terminal signature 635 645 5.6E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_26390 3335fb61c0253b3279619500083aca79 707 PRINTS PR00344 Bacterial sensor protein C-terminal signature 617 631 5.6E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_26390 3335fb61c0253b3279619500083aca79 707 PRINTS PR00344 Bacterial sensor protein C-terminal signature 671 684 5.6E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_26390 3335fb61c0253b3279619500083aca79 707 PRINTS PR00344 Bacterial sensor protein C-terminal signature 647 665 5.6E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_26390 3335fb61c0253b3279619500083aca79 707 SUPERFAMILY SSF103190 191 329 8.95E-13 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily TSH58p_26390 3335fb61c0253b3279619500083aca79 707 Gene3D G3DSA:1.20.1480.50 333 423 2.8E-7 T 14-10-2018 TSH58p_26390 3335fb61c0253b3279619500083aca79 707 Gene3D G3DSA:1.10.287.130 436 521 1.5E-22 T 14-10-2018 TSH58p_29705 a405bc20f8f110fa99be0d0c57baf927 343 Pfam PF01926 50S ribosome-binding GTPase 52 167 1.5E-23 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 TSH58p_29705 a405bc20f8f110fa99be0d0c57baf927 343 Pfam PF07650 KH domain 250 326 3.7E-17 T 14-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_29705 a405bc20f8f110fa99be0d0c57baf927 343 Gene3D G3DSA:3.40.50.300 45 225 3.4E-44 T 14-10-2018 TSH58p_29705 a405bc20f8f110fa99be0d0c57baf927 343 Gene3D G3DSA:3.30.300.20 227 340 5.4E-37 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta TSH58p_29705 a405bc20f8f110fa99be0d0c57baf927 343 Hamap MF_00367 GTPase Era [era]. 47 338 32.861 T 14-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_29705 a405bc20f8f110fa99be0d0c57baf927 343 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 49 210 1.4E-23 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSH58p_29705 a405bc20f8f110fa99be0d0c57baf927 343 TIGRFAM TIGR00436 era: GTP-binding protein Era 50 321 2.9E-75 T 14-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_29705 a405bc20f8f110fa99be0d0c57baf927 343 SUPERFAMILY SSF54814 223 338 1.96E-38 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TSH58p_29705 a405bc20f8f110fa99be0d0c57baf927 343 SUPERFAMILY SSF52540 52 253 8.09E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_31735 94d055632f996b4067495699b0d16270 632 SMART SM00564 200 243 300.0 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSH58p_31735 94d055632f996b4067495699b0d16270 632 SMART SM00564 462 527 36.0 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSH58p_31735 94d055632f996b4067495699b0d16270 632 SMART SM00564 105 137 2.3E-6 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSH58p_31735 94d055632f996b4067495699b0d16270 632 SMART SM00564 536 568 2.6E-7 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSH58p_31735 94d055632f996b4067495699b0d16270 632 SMART SM00564 155 186 1.0E-5 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSH58p_31735 94d055632f996b4067495699b0d16270 632 SUPERFAMILY SSF50998 52 619 4.32E-136 T 14-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TSH58p_31735 94d055632f996b4067495699b0d16270 632 Gene3D G3DSA:2.140.10.10 43 626 1.1E-227 T 14-10-2018 TSH58p_31735 94d055632f996b4067495699b0d16270 632 Pfam PF01011 PQQ enzyme repeat 542 578 6.0E-10 T 14-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat TSH58p_31735 94d055632f996b4067495699b0d16270 632 TIGRFAM TIGR03075 PQQ_enz_alc_DH: PQQ-dependent dehydrogenase, methanol/ethanol family 41 596 2.4E-224 T 14-10-2018 IPR017512 PQQ-dependent dehydrogenase, methanol/ethanol family GO:0005509|GO:0016020|GO:0016614|GO:0055114 TSH58p_31735 94d055632f996b4067495699b0d16270 632 ProSitePatterns PS00364 Bacterial quinoprotein dehydrogenases signature 2. 288 309 - T 14-10-2018 IPR001479 Quinoprotein dehydrogenase, conserved site GO:0030288|GO:0055114 TSH58p_31735 94d055632f996b4067495699b0d16270 632 Pfam PF13360 PQQ-like domain 90 284 3.0E-16 T 14-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat TSH58p_05455 a4859e92e59563af8fa973c47df8b502 280 Gene3D G3DSA:3.40.250.10 3 147 1.2E-33 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily TSH58p_05455 a4859e92e59563af8fa973c47df8b502 280 Pfam PF00581 Rhodanese-like domain 13 125 5.3E-13 T 14-10-2018 IPR001763 Rhodanese-like domain TSH58p_05455 a4859e92e59563af8fa973c47df8b502 280 Pfam PF00581 Rhodanese-like domain 161 268 3.5E-7 T 14-10-2018 IPR001763 Rhodanese-like domain TSH58p_05455 a4859e92e59563af8fa973c47df8b502 280 Gene3D G3DSA:3.40.250.10 155 279 1.0E-25 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily TSH58p_05455 a4859e92e59563af8fa973c47df8b502 280 SUPERFAMILY SSF52821 154 277 4.58E-22 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily TSH58p_05455 a4859e92e59563af8fa973c47df8b502 280 SMART SM00450 152 272 2.1E-9 T 14-10-2018 IPR001763 Rhodanese-like domain TSH58p_05455 a4859e92e59563af8fa973c47df8b502 280 SMART SM00450 10 129 2.6E-13 T 14-10-2018 IPR001763 Rhodanese-like domain TSH58p_05455 a4859e92e59563af8fa973c47df8b502 280 SUPERFAMILY SSF52821 7 146 1.96E-28 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily TSH58p_10735 a253b630d5f657663a3e13cd8fc45524 370 Gene3D G3DSA:3.40.50.2300 35 348 4.3E-110 T 14-10-2018 TSH58p_10735 a253b630d5f657663a3e13cd8fc45524 370 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 28 44 1.2E-32 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_10735 a253b630d5f657663a3e13cd8fc45524 370 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 331 346 1.2E-32 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_10735 a253b630d5f657663a3e13cd8fc45524 370 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 50 66 1.2E-32 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_10735 a253b630d5f657663a3e13cd8fc45524 370 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 90 100 1.2E-32 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_10735 a253b630d5f657663a3e13cd8fc45524 370 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 279 292 1.2E-32 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_10735 a253b630d5f657663a3e13cd8fc45524 370 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 256 274 1.2E-32 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_10735 a253b630d5f657663a3e13cd8fc45524 370 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 69 87 1.2E-32 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_10735 a253b630d5f657663a3e13cd8fc45524 370 Pfam PF13458 Periplasmic binding protein 28 364 2.5E-60 T 14-10-2018 IPR028081 Leucine-binding protein domain TSH58p_10735 a253b630d5f657663a3e13cd8fc45524 370 Gene3D G3DSA:3.40.50.2300 146 274 4.3E-110 T 14-10-2018 TSH58p_10735 a253b630d5f657663a3e13cd8fc45524 370 SUPERFAMILY SSF53822 27 369 8.95E-95 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_22325 2dea4d080385c54c55df005ba332d772 570 Gene3D G3DSA:2.30.30.40 501 568 6.8E-9 T 14-10-2018 TSH58p_22325 2dea4d080385c54c55df005ba332d772 570 SMART SM00287 507 568 1.6E-4 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type TSH58p_22325 2dea4d080385c54c55df005ba332d772 570 Pfam PF14020 Protein of unknown function (DUF4236) 3 56 1.3E-18 T 14-10-2018 IPR025330 Domain of unknown function DUF4236 TSH58p_22325 2dea4d080385c54c55df005ba332d772 570 Pfam PF06347 Bacterial SH3 domain 513 561 1.8E-5 T 14-10-2018 IPR010466 Protein of unknown function DUF1058 TSH58p_10745 30a05926e83f3ef7d8426fa9205aa42c 524 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 3 467 19.273 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSH58p_10745 30a05926e83f3ef7d8426fa9205aa42c 524 PRINTS PR01806 Virulence factor MviN signature 157 178 2.7E-70 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSH58p_10745 30a05926e83f3ef7d8426fa9205aa42c 524 PRINTS PR01806 Virulence factor MviN signature 409 426 2.7E-70 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSH58p_10745 30a05926e83f3ef7d8426fa9205aa42c 524 PRINTS PR01806 Virulence factor MviN signature 357 376 2.7E-70 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSH58p_10745 30a05926e83f3ef7d8426fa9205aa42c 524 PRINTS PR01806 Virulence factor MviN signature 33 52 2.7E-70 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSH58p_10745 30a05926e83f3ef7d8426fa9205aa42c 524 PRINTS PR01806 Virulence factor MviN signature 259 285 2.7E-70 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSH58p_10745 30a05926e83f3ef7d8426fa9205aa42c 524 PRINTS PR01806 Virulence factor MviN signature 52 68 2.7E-70 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSH58p_10745 30a05926e83f3ef7d8426fa9205aa42c 524 PRINTS PR01806 Virulence factor MviN signature 133 157 2.7E-70 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSH58p_10745 30a05926e83f3ef7d8426fa9205aa42c 524 PIRSF PIRSF002869 1 514 2.9E-144 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSH58p_10745 30a05926e83f3ef7d8426fa9205aa42c 524 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 4 489 6.9E-125 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSH58p_10745 30a05926e83f3ef7d8426fa9205aa42c 524 Pfam PF03023 MviN-like protein 29 453 1.5E-112 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSH58p_22270 e3d8a664d598c4a88e5db4a22452fd6c 396 SUPERFAMILY SSF56954 1 395 1.96E-45 T 14-10-2018 TSH58p_22270 e3d8a664d598c4a88e5db4a22452fd6c 396 Pfam PF02321 Outer membrane efflux protein 220 393 3.3E-17 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 TSH58p_22270 e3d8a664d598c4a88e5db4a22452fd6c 396 Pfam PF02321 Outer membrane efflux protein 32 203 1.1E-10 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 TSH58p_22270 e3d8a664d598c4a88e5db4a22452fd6c 396 Gene3D G3DSA:1.20.1600.10 17 394 3.9E-42 T 14-10-2018 TSH58p_22700 c0f7152b68c3e7f0c003fb2f8afc22da 120 Pfam PF02924 Bacteriophage lambda head decoration protein D 13 115 7.0E-22 T 14-10-2018 IPR004195 Head decoration protein D TSH58p_11550 1f9df3e5baa76f5f50bda03424c7089d 319 SUPERFAMILY SSF55073 144 304 2.67E-41 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_11550 1f9df3e5baa76f5f50bda03424c7089d 319 Gene3D G3DSA:3.30.70.270 139 310 2.0E-46 T 14-10-2018 TSH58p_11550 1f9df3e5baa76f5f50bda03424c7089d 319 SUPERFAMILY SSF52172 9 133 1.18E-36 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_11550 1f9df3e5baa76f5f50bda03424c7089d 319 Gene3D G3DSA:3.40.50.2300 2 138 5.2E-35 T 14-10-2018 TSH58p_11550 1f9df3e5baa76f5f50bda03424c7089d 319 SMART SM00267 128 305 4.5E-45 T 14-10-2018 IPR000160 GGDEF domain TSH58p_11550 1f9df3e5baa76f5f50bda03424c7089d 319 SMART SM00448 9 122 4.8E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_11550 1f9df3e5baa76f5f50bda03424c7089d 319 Pfam PF00072 Response regulator receiver domain 11 122 2.0E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_11550 1f9df3e5baa76f5f50bda03424c7089d 319 Pfam PF00990 Diguanylate cyclase, GGDEF domain 140 301 1.2E-37 T 14-10-2018 IPR000160 GGDEF domain TSH58p_11550 1f9df3e5baa76f5f50bda03424c7089d 319 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 138 304 3.1E-39 T 14-10-2018 IPR000160 GGDEF domain TSH58p_30870 c822d6b7b2810f6fea8d62076b7be581 147 Gene3D G3DSA:3.10.180.10 2 143 2.8E-31 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSH58p_30870 c822d6b7b2810f6fea8d62076b7be581 147 SUPERFAMILY SSF54593 5 142 1.02E-18 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSH58p_30870 c822d6b7b2810f6fea8d62076b7be581 147 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 129 9.7E-20 T 14-10-2018 TSH58p_20905 dd4c76eaed12d8d4a6f9acd3f499ad5c 343 Gene3D G3DSA:3.40.190.170 21 335 8.7E-59 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily TSH58p_20905 dd4c76eaed12d8d4a6f9acd3f499ad5c 343 SUPERFAMILY SSF53850 152 274 3.26E-5 T 14-10-2018 TSH58p_20905 dd4c76eaed12d8d4a6f9acd3f499ad5c 343 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 51 323 3.8E-43 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 TSH58p_27465 292e2ac019fe26419cb2e44c2a253a93 353 SUPERFAMILY SSF103088 223 339 1.06E-17 T 14-10-2018 IPR036737 OmpA-like domain superfamily TSH58p_27465 292e2ac019fe26419cb2e44c2a253a93 353 Pfam PF00691 OmpA family 236 327 1.3E-10 T 14-10-2018 IPR006665 OmpA-like domain TSH58p_27465 292e2ac019fe26419cb2e44c2a253a93 353 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 15 66 1.4E-18 T 14-10-2018 IPR025713 Motility protein B, N-terminal domain TSH58p_27465 292e2ac019fe26419cb2e44c2a253a93 353 Gene3D G3DSA:3.30.1330.60 183 353 5.6E-48 T 14-10-2018 IPR036737 OmpA-like domain superfamily TSH58p_12770 afd920eb432bc2c6d4d7b526ed487c87 374 Pfam PF01266 FAD dependent oxidoreductase 5 351 1.3E-47 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TSH58p_12770 afd920eb432bc2c6d4d7b526ed487c87 374 SUPERFAMILY SSF54373 215 315 5.89E-8 T 14-10-2018 TSH58p_12770 afd920eb432bc2c6d4d7b526ed487c87 374 Gene3D G3DSA:3.50.50.60 5 354 1.6E-83 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_12770 afd920eb432bc2c6d4d7b526ed487c87 374 Gene3D G3DSA:3.30.9.10 59 316 1.6E-83 T 14-10-2018 TSH58p_12770 afd920eb432bc2c6d4d7b526ed487c87 374 SUPERFAMILY SSF51905 4 359 3.17E-42 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_21235 7c2b6057c5cbcdc7f85ab748b8830914 143 Pfam PF01986 Domain of unknown function DUF123 43 128 1.8E-18 T 14-10-2018 IPR002837 Protein of unknown function DUF123 TSH58p_14390 527646354b3016f40820421ffa4cccee 607 Gene3D G3DSA:1.10.287.380 520 601 4.3E-23 T 14-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 TSH58p_14390 527646354b3016f40820421ffa4cccee 607 Pfam PF00005 ABC transporter 307 441 1.5E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_14390 527646354b3016f40820421ffa4cccee 607 SMART SM00382 315 486 4.3E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_14390 527646354b3016f40820421ffa4cccee 607 SMART SM00382 32 197 3.2E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_14390 527646354b3016f40820421ffa4cccee 607 Pfam PF16326 ABC transporter C-terminal domain 528 596 1.5E-20 T 14-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 TSH58p_14390 527646354b3016f40820421ffa4cccee 607 Pfam PF00005 ABC transporter 24 152 1.2E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_14390 527646354b3016f40820421ffa4cccee 607 SUPERFAMILY SSF52540 10 201 3.93E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_14390 527646354b3016f40820421ffa4cccee 607 Gene3D G3DSA:3.40.50.300 251 519 1.1E-60 T 14-10-2018 TSH58p_14390 527646354b3016f40820421ffa4cccee 607 Gene3D G3DSA:3.40.50.300 2 231 5.7E-57 T 14-10-2018 TSH58p_14390 527646354b3016f40820421ffa4cccee 607 ProSitePatterns PS00211 ABC transporters family signature. 413 427 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_14390 527646354b3016f40820421ffa4cccee 607 SUPERFAMILY SSF52540 282 493 2.58E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_11355 aa471d4cf41b30655d6b9fe3a529d1da 277 Gene3D G3DSA:3.10.580.10 32 183 2.5E-54 T 14-10-2018 TSH58p_11355 aa471d4cf41b30655d6b9fe3a529d1da 277 SMART SM00116 59 108 1.3 T 14-10-2018 IPR000644 CBS domain TSH58p_11355 aa471d4cf41b30655d6b9fe3a529d1da 277 SMART SM00116 121 169 4.2 T 14-10-2018 IPR000644 CBS domain TSH58p_11355 aa471d4cf41b30655d6b9fe3a529d1da 277 Gene3D G3DSA:3.30.465.10 184 266 4.1E-25 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TSH58p_11355 aa471d4cf41b30655d6b9fe3a529d1da 277 SUPERFAMILY SSF54631 45 182 1.07E-32 T 14-10-2018 TSH58p_11355 aa471d4cf41b30655d6b9fe3a529d1da 277 Pfam PF00571 CBS domain 51 108 2.3E-6 T 14-10-2018 IPR000644 CBS domain TSH58p_11355 aa471d4cf41b30655d6b9fe3a529d1da 277 Pfam PF00571 CBS domain 120 169 7.2E-7 T 14-10-2018 IPR000644 CBS domain TSH58p_11355 aa471d4cf41b30655d6b9fe3a529d1da 277 Pfam PF03471 Transporter associated domain 186 265 1.0E-18 T 14-10-2018 IPR005170 Transporter-associated domain TSH58p_11355 aa471d4cf41b30655d6b9fe3a529d1da 277 SMART SM01091 185 267 2.9E-24 T 14-10-2018 IPR005170 Transporter-associated domain TSH58p_11355 aa471d4cf41b30655d6b9fe3a529d1da 277 SUPERFAMILY SSF56176 183 269 3.54E-19 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TSH58p_14765 92f4ed8b94608c8aca2ab6ffd7c92aa2 308 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 87 109 - T 14-10-2018 IPR030470 UbiA prenyltransferase conserved site TSH58p_14765 92f4ed8b94608c8aca2ab6ffd7c92aa2 308 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 24 308 28.902 T 14-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 TSH58p_14765 92f4ed8b94608c8aca2ab6ffd7c92aa2 308 Pfam PF01040 UbiA prenyltransferase family 47 291 2.4E-62 T 14-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 TSH58p_14765 92f4ed8b94608c8aca2ab6ffd7c92aa2 308 Gene3D G3DSA:1.20.120.1780 192 308 3.6E-13 T 14-10-2018 TSH58p_14765 92f4ed8b94608c8aca2ab6ffd7c92aa2 308 Gene3D G3DSA:1.10.357.140 44 191 5.8E-47 T 14-10-2018 TSH58p_14765 92f4ed8b94608c8aca2ab6ffd7c92aa2 308 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 30 306 1.4E-113 T 14-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 TSH58p_13425 8329cdfc0af48052b2c0004606f00854 340 Pfam PF14841 FliG middle domain 122 194 5.5E-24 T 14-10-2018 IPR032779 Flagellar motor switch protein FliG, middle domain TSH58p_13425 8329cdfc0af48052b2c0004606f00854 340 SUPERFAMILY SSF48029 122 329 1.57E-61 T 14-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical TSH58p_13425 8329cdfc0af48052b2c0004606f00854 340 Gene3D G3DSA:1.10.220.30 201 339 1.9E-42 T 14-10-2018 TSH58p_13425 8329cdfc0af48052b2c0004606f00854 340 Gene3D G3DSA:1.10.220.30 93 198 1.5E-25 T 14-10-2018 TSH58p_13425 8329cdfc0af48052b2c0004606f00854 340 Gene3D G3DSA:1.10.220.30 5 88 9.4E-18 T 14-10-2018 TSH58p_13425 8329cdfc0af48052b2c0004606f00854 340 Pfam PF01706 FliG C-terminal domain 223 329 2.9E-39 T 14-10-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal TSH58p_13425 8329cdfc0af48052b2c0004606f00854 340 PIRSF PIRSF003161 6 339 3.2E-111 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 TSH58p_13425 8329cdfc0af48052b2c0004606f00854 340 SUPERFAMILY SSF48029 8 121 2.22E-21 T 14-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical TSH58p_13425 8329cdfc0af48052b2c0004606f00854 340 Pfam PF14842 FliG N-terminal domain 12 113 5.7E-27 T 14-10-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain TSH58p_13425 8329cdfc0af48052b2c0004606f00854 340 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 7 336 9.5E-79 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 TSH58p_13425 8329cdfc0af48052b2c0004606f00854 340 PRINTS PR00954 Flagellar motor switch protein FliG signature 41 67 3.2E-61 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 TSH58p_13425 8329cdfc0af48052b2c0004606f00854 340 PRINTS PR00954 Flagellar motor switch protein FliG signature 12 28 3.2E-61 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 TSH58p_13425 8329cdfc0af48052b2c0004606f00854 340 PRINTS PR00954 Flagellar motor switch protein FliG signature 200 225 3.2E-61 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 TSH58p_13425 8329cdfc0af48052b2c0004606f00854 340 PRINTS PR00954 Flagellar motor switch protein FliG signature 120 143 3.2E-61 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 TSH58p_13425 8329cdfc0af48052b2c0004606f00854 340 PRINTS PR00954 Flagellar motor switch protein FliG signature 277 303 3.2E-61 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 TSH58p_13425 8329cdfc0af48052b2c0004606f00854 340 PRINTS PR00954 Flagellar motor switch protein FliG signature 253 273 3.2E-61 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 TSH58p_13425 8329cdfc0af48052b2c0004606f00854 340 PRINTS PR00954 Flagellar motor switch protein FliG signature 231 251 3.2E-61 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 TSH58p_07550 545bc3c71bfa0f81fdcb6a83a7f44b70 518 SUPERFAMILY SSF53146 380 491 1.57E-31 T 14-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TSH58p_07550 545bc3c71bfa0f81fdcb6a83a7f44b70 518 Gene3D G3DSA:3.30.420.130 376 493 1.9E-28 T 14-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TSH58p_07550 545bc3c71bfa0f81fdcb6a83a7f44b70 518 Gene3D G3DSA:3.20.20.70 60 331 3.6E-28 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_07550 545bc3c71bfa0f81fdcb6a83a7f44b70 518 Pfam PF04055 Radical SAM superfamily 73 252 8.8E-24 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSH58p_07550 545bc3c71bfa0f81fdcb6a83a7f44b70 518 TIGRFAM TIGR01290 nifB: nitrogenase cofactor biosynthesis protein NifB 45 484 6.4E-202 T 14-10-2018 IPR005980 Nitrogenase cofactor biosynthesis protein NifB GO:0009108|GO:0009399 TSH58p_07550 545bc3c71bfa0f81fdcb6a83a7f44b70 518 SUPERFAMILY SSF102114 61 276 7.59E-34 T 14-10-2018 TSH58p_07550 545bc3c71bfa0f81fdcb6a83a7f44b70 518 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 391 480 1.2E-21 T 14-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TSH58p_07550 545bc3c71bfa0f81fdcb6a83a7f44b70 518 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 73 84 - T 14-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_00965 43ac221e7bb2c30b0eaf14cde09c12f5 141 Gene3D G3DSA:3.30.300.20 1 141 8.4E-42 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta TSH58p_00965 43ac221e7bb2c30b0eaf14cde09c12f5 141 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 4 138 9.4E-58 T 14-10-2018 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 TSH58p_00965 43ac221e7bb2c30b0eaf14cde09c12f5 141 Pfam PF02566 OsmC-like protein 41 136 5.4E-21 T 14-10-2018 IPR003718 OsmC/Ohr family TSH58p_00965 43ac221e7bb2c30b0eaf14cde09c12f5 141 SUPERFAMILY SSF82784 4 131 9.95E-38 T 14-10-2018 IPR036102 OsmC/Ohr superfamily TSH58p_25800 a9af79c4d9b2093623b1baa6656a2dee 219 SMART SM00862 145 216 6.2E-26 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_25800 a9af79c4d9b2093623b1baa6656a2dee 219 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 2.0E-23 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_25800 a9af79c4d9b2093623b1baa6656a2dee 219 SUPERFAMILY SSF52172 1 180 4.98E-38 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_25800 a9af79c4d9b2093623b1baa6656a2dee 219 Gene3D G3DSA:1.10.10.10 122 218 1.5E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_25800 a9af79c4d9b2093623b1baa6656a2dee 219 SMART SM00448 1 112 9.1E-39 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_25800 a9af79c4d9b2093623b1baa6656a2dee 219 Gene3D G3DSA:3.40.50.2300 1 121 4.4E-41 T 14-10-2018 TSH58p_25800 a9af79c4d9b2093623b1baa6656a2dee 219 Pfam PF00072 Response regulator receiver domain 4 113 7.7E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_02975 8c274018ede6650c928f6ff2b9dfa767 387 Gene3D G3DSA:2.40.50.940 249 311 5.1E-11 T 14-10-2018 TSH58p_02975 8c274018ede6650c928f6ff2b9dfa767 387 SMART SM00382 54 237 6.7E-20 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_02975 8c274018ede6650c928f6ff2b9dfa767 387 Gene3D G3DSA:3.40.50.300 27 248 2.8E-69 T 14-10-2018 TSH58p_02975 8c274018ede6650c928f6ff2b9dfa767 387 Pfam PF08402 TOBE domain 305 372 5.6E-11 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TSH58p_02975 8c274018ede6650c928f6ff2b9dfa767 387 Gene3D G3DSA:2.40.50.140 312 352 5.1E-11 T 14-10-2018 TSH58p_02975 8c274018ede6650c928f6ff2b9dfa767 387 Pfam PF00005 ABC transporter 45 188 1.0E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_02975 8c274018ede6650c928f6ff2b9dfa767 387 SUPERFAMILY SSF50331 263 371 4.87E-14 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSH58p_02975 8c274018ede6650c928f6ff2b9dfa767 387 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_02975 8c274018ede6650c928f6ff2b9dfa767 387 SUPERFAMILY SSF52540 30 269 3.84E-84 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_10240 747490f5bdc2cfaf5da5f27f13435adb 522 SUPERFAMILY SSF52172 21 160 2.56E-10 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_10240 747490f5bdc2cfaf5da5f27f13435adb 522 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 348 513 3.3E-48 T 14-10-2018 IPR000160 GGDEF domain TSH58p_10240 747490f5bdc2cfaf5da5f27f13435adb 522 Pfam PF00072 Response regulator receiver domain 25 134 2.7E-6 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_10240 747490f5bdc2cfaf5da5f27f13435adb 522 Pfam PF00990 Diguanylate cyclase, GGDEF domain 352 509 5.4E-41 T 14-10-2018 IPR000160 GGDEF domain TSH58p_10240 747490f5bdc2cfaf5da5f27f13435adb 522 Gene3D G3DSA:3.40.50.2300 24 157 1.7E-11 T 14-10-2018 TSH58p_10240 747490f5bdc2cfaf5da5f27f13435adb 522 Pfam PF11849 Domain of unknown function (DUF3369) 145 323 8.3E-47 T 14-10-2018 IPR021800 Domain of unknown function DUF3369 TSH58p_10240 747490f5bdc2cfaf5da5f27f13435adb 522 SMART SM00267 341 513 1.4E-59 T 14-10-2018 IPR000160 GGDEF domain TSH58p_10240 747490f5bdc2cfaf5da5f27f13435adb 522 SUPERFAMILY SSF55073 357 514 1.26E-47 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_10240 747490f5bdc2cfaf5da5f27f13435adb 522 Gene3D G3DSA:3.30.70.270 341 515 1.7E-56 T 14-10-2018 TSH58p_02090 7748f18916b48f706dd6a531ee42fadf 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 2.5E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_02090 7748f18916b48f706dd6a531ee42fadf 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 2.5E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_02090 7748f18916b48f706dd6a531ee42fadf 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 2.5E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_02090 7748f18916b48f706dd6a531ee42fadf 261 Gene3D G3DSA:3.40.50.720 4 260 6.4E-78 T 14-10-2018 TSH58p_02090 7748f18916b48f706dd6a531ee42fadf 261 SUPERFAMILY SSF51735 15 259 1.15E-76 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_02090 7748f18916b48f706dd6a531ee42fadf 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 7.8E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_02090 7748f18916b48f706dd6a531ee42fadf 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 7.8E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_02090 7748f18916b48f706dd6a531ee42fadf 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 7.8E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_02090 7748f18916b48f706dd6a531ee42fadf 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 7.8E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_02090 7748f18916b48f706dd6a531ee42fadf 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 18 35 7.8E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_02090 7748f18916b48f706dd6a531ee42fadf 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 7.8E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_02090 7748f18916b48f706dd6a531ee42fadf 261 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 17 196 0.0018 T 14-10-2018 TSH58p_02090 7748f18916b48f706dd6a531ee42fadf 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_02090 7748f18916b48f706dd6a531ee42fadf 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 25 258 8.9E-63 T 14-10-2018 TSH58p_19640 ba808d3395eaf9d52c365578a93c354d 381 Pfam PF13458 Periplasmic binding protein 34 373 2.2E-64 T 14-10-2018 IPR028081 Leucine-binding protein domain TSH58p_19640 ba808d3395eaf9d52c365578a93c354d 381 SUPERFAMILY SSF53822 34 378 2.47E-89 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_19640 ba808d3395eaf9d52c365578a93c354d 381 Gene3D G3DSA:3.40.50.2300 38 355 5.9E-110 T 14-10-2018 TSH58p_19640 ba808d3395eaf9d52c365578a93c354d 381 Gene3D G3DSA:3.40.50.2300 152 286 5.9E-110 T 14-10-2018 TSH58p_28045 b7eb1ab818129e0e5bc61671e1e16ac9 90 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 76 3.8E-17 T 14-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TSH58p_28045 b7eb1ab818129e0e5bc61671e1e16ac9 90 SUPERFAMILY SSF159127 1 83 1.18E-19 T 14-10-2018 IPR037254 HupF/HypC superfamily TSH58p_28045 b7eb1ab818129e0e5bc61671e1e16ac9 90 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 14-10-2018 IPR019812 Hydrogenase assembly chaperone, conserved site TSH58p_28045 b7eb1ab818129e0e5bc61671e1e16ac9 90 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 5.6E-10 T 14-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TSH58p_28045 b7eb1ab818129e0e5bc61671e1e16ac9 90 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 17 33 5.6E-10 T 14-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TSH58p_28045 b7eb1ab818129e0e5bc61671e1e16ac9 90 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 38 54 5.6E-10 T 14-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TSH58p_28045 b7eb1ab818129e0e5bc61671e1e16ac9 90 Gene3D G3DSA:2.40.50.970 1 74 1.7E-15 T 14-10-2018 IPR037254 HupF/HypC superfamily TSH58p_28045 b7eb1ab818129e0e5bc61671e1e16ac9 90 Pfam PF01455 HupF/HypC family 1 59 1.6E-18 T 14-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TSH58p_07175 56bbc6124f5ec855017607d5ee2f465d 2358 TIGRFAM TIGR02675 tape_meas_nterm: tape measure domain 158 230 8.5E-11 T 14-10-2018 IPR013491 Caudovirus, tape measure, N-terminal TSH58p_31080 6ef88dd928dc528547c8485fe9da4f02 174 SUPERFAMILY SSF88946 12 90 1.22E-11 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_31080 6ef88dd928dc528547c8485fe9da4f02 174 Pfam PF04542 Sigma-70 region 2 15 81 2.1E-9 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_31080 6ef88dd928dc528547c8485fe9da4f02 174 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 167 4.4E-25 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TSH58p_31080 6ef88dd928dc528547c8485fe9da4f02 174 Gene3D G3DSA:1.10.10.10 90 172 4.8E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_31080 6ef88dd928dc528547c8485fe9da4f02 174 SUPERFAMILY SSF88659 106 169 2.18E-16 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSH58p_31080 6ef88dd928dc528547c8485fe9da4f02 174 Gene3D G3DSA:1.10.1740.10 5 77 6.0E-7 T 14-10-2018 TSH58p_31080 6ef88dd928dc528547c8485fe9da4f02 174 Pfam PF08281 Sigma-70, region 4 113 164 7.7E-17 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_25150 5ef9b40adb4fdc6bd229b1a45baf60d8 227 Gene3D G3DSA:3.10.20.30 53 135 1.7E-32 T 14-10-2018 IPR012675 Beta-grasp domain superfamily TSH58p_25150 5ef9b40adb4fdc6bd229b1a45baf60d8 227 SUPERFAMILY SSF54292 61 137 1.22E-26 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TSH58p_25150 5ef9b40adb4fdc6bd229b1a45baf60d8 227 SUPERFAMILY SSF47741 143 224 4.97E-28 T 14-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily TSH58p_25150 5ef9b40adb4fdc6bd229b1a45baf60d8 227 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 64 113 1.8E-9 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 TSH58p_25150 5ef9b40adb4fdc6bd229b1a45baf60d8 227 Gene3D G3DSA:1.10.150.120 136 226 4.0E-35 T 14-10-2018 TSH58p_25150 5ef9b40adb4fdc6bd229b1a45baf60d8 227 Pfam PF01799 [2Fe-2S] binding domain 132 219 1.4E-29 T 14-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 TSH58p_25150 5ef9b40adb4fdc6bd229b1a45baf60d8 227 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 98 106 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 TSH58p_23905 0b0d02105d34e0ae102aaece2b125d93 254 SUPERFAMILY SSF46626 25 218 7.09E-69 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_23905 0b0d02105d34e0ae102aaece2b125d93 254 SUPERFAMILY SSF81496 219 253 1.96E-6 T 14-10-2018 IPR021157 Cytochrome c1, transmembrane anchor, C-terminal Reactome: R-HSA-1268020|Reactome: R-HSA-611105 TSH58p_23905 0b0d02105d34e0ae102aaece2b125d93 254 Gene3D G3DSA:1.10.760.10 23 219 7.8E-84 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_23905 0b0d02105d34e0ae102aaece2b125d93 254 PRINTS PR00603 Cytochrome C1 signature 52 71 8.2E-64 T 14-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 TSH58p_23905 0b0d02105d34e0ae102aaece2b125d93 254 PRINTS PR00603 Cytochrome C1 signature 180 199 8.2E-64 T 14-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 TSH58p_23905 0b0d02105d34e0ae102aaece2b125d93 254 PRINTS PR00603 Cytochrome C1 signature 169 180 8.2E-64 T 14-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 TSH58p_23905 0b0d02105d34e0ae102aaece2b125d93 254 PRINTS PR00603 Cytochrome C1 signature 97 117 8.2E-64 T 14-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 TSH58p_23905 0b0d02105d34e0ae102aaece2b125d93 254 PRINTS PR00603 Cytochrome C1 signature 200 219 8.2E-64 T 14-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 TSH58p_23905 0b0d02105d34e0ae102aaece2b125d93 254 PRINTS PR00603 Cytochrome C1 signature 32 51 8.2E-64 T 14-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 TSH58p_23905 0b0d02105d34e0ae102aaece2b125d93 254 PRINTS PR00603 Cytochrome C1 signature 130 154 8.2E-64 T 14-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 TSH58p_23905 0b0d02105d34e0ae102aaece2b125d93 254 PRINTS PR00603 Cytochrome C1 signature 219 234 8.2E-64 T 14-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 TSH58p_23905 0b0d02105d34e0ae102aaece2b125d93 254 Gene3D G3DSA:1.20.5.100 220 254 1.2E-7 T 14-10-2018 TSH58p_23905 0b0d02105d34e0ae102aaece2b125d93 254 Pfam PF02167 Cytochrome C1 family 34 252 1.5E-91 T 14-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 TSH58p_20715 604a586b1d4a11c18efa9dae0c1a8c8e 355 Pfam PF00437 Type II/IV secretion system protein 5 281 1.6E-81 T 14-10-2018 IPR001482 Type II/IV secretion system protein TSH58p_20715 604a586b1d4a11c18efa9dae0c1a8c8e 355 Gene3D G3DSA:3.30.450.380 1 100 1.1E-31 T 14-10-2018 TSH58p_20715 604a586b1d4a11c18efa9dae0c1a8c8e 355 Gene3D G3DSA:3.40.50.300 103 338 3.9E-71 T 14-10-2018 TSH58p_20715 604a586b1d4a11c18efa9dae0c1a8c8e 355 SUPERFAMILY SSF52540 1 315 1.13E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_25135 a99f91ac7708a5bace60b1fa97609273 279 SUPERFAMILY SSF54637 80 145 2.35E-8 T 14-10-2018 IPR029069 HotDog domain superfamily TSH58p_25135 a99f91ac7708a5bace60b1fa97609273 279 SUPERFAMILY SSF54637 159 268 1.02E-15 T 14-10-2018 IPR029069 HotDog domain superfamily TSH58p_25135 a99f91ac7708a5bace60b1fa97609273 279 Pfam PF13452 N-terminal half of MaoC dehydratase 71 137 2.9E-11 T 14-10-2018 IPR039569 N-terminal of MaoC-like dehydratase Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-9033241|Reactome: R-HSA-9033500 TSH58p_25135 a99f91ac7708a5bace60b1fa97609273 279 Gene3D G3DSA:3.10.129.10 13 152 2.5E-13 T 14-10-2018 TSH58p_25135 a99f91ac7708a5bace60b1fa97609273 279 Gene3D G3DSA:3.10.129.10 159 278 2.7E-16 T 14-10-2018 TSH58p_13585 2b718f3a809e7709ce97791cfd2eec3b 490 Gene3D G3DSA:1.10.287.130 184 307 2.0E-8 T 14-10-2018 TSH58p_13585 2b718f3a809e7709ce97791cfd2eec3b 490 SUPERFAMILY SSF47384 234 307 2.35E-5 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_13585 2b718f3a809e7709ce97791cfd2eec3b 490 SUPERFAMILY SSF55874 335 466 6.42E-27 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_13585 2b718f3a809e7709ce97791cfd2eec3b 490 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 447 7.8E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_13585 2b718f3a809e7709ce97791cfd2eec3b 490 PRINTS PR00344 Bacterial sensor protein C-terminal signature 453 466 7.8E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_13585 2b718f3a809e7709ce97791cfd2eec3b 490 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 413 7.8E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_13585 2b718f3a809e7709ce97791cfd2eec3b 490 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 427 7.8E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_13585 2b718f3a809e7709ce97791cfd2eec3b 490 Gene3D G3DSA:3.30.565.10 317 470 3.3E-28 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_13585 2b718f3a809e7709ce97791cfd2eec3b 490 SMART SM00387 363 469 2.6E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_13585 2b718f3a809e7709ce97791cfd2eec3b 490 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 364 468 8.2E-15 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_05690 f86d617d223b2c8c821e03530c6fb72a 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.1E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_05690 f86d617d223b2c8c821e03530c6fb72a 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.1E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_05690 f86d617d223b2c8c821e03530c6fb72a 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.1E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_05690 f86d617d223b2c8c821e03530c6fb72a 306 Gene3D G3DSA:3.40.190.10 100 281 4.4E-47 T 14-10-2018 TSH58p_05690 f86d617d223b2c8c821e03530c6fb72a 306 Pfam PF03466 LysR substrate binding domain 91 285 5.9E-26 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_05690 f86d617d223b2c8c821e03530c6fb72a 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 1.2E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_05690 f86d617d223b2c8c821e03530c6fb72a 306 Gene3D G3DSA:1.10.10.10 4 94 3.1E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_05690 f86d617d223b2c8c821e03530c6fb72a 306 Gene3D G3DSA:3.40.190.10 160 254 4.4E-47 T 14-10-2018 TSH58p_05690 f86d617d223b2c8c821e03530c6fb72a 306 SUPERFAMILY SSF53850 92 287 1.68E-28 T 14-10-2018 TSH58p_05690 f86d617d223b2c8c821e03530c6fb72a 306 SUPERFAMILY SSF46785 4 111 2.4E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_28875 2aba8ce2a9617f7f410f38ec66d15840 127 SMART SM00448 7 120 6.7E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_28875 2aba8ce2a9617f7f410f38ec66d15840 127 SUPERFAMILY SSF52172 5 123 6.4E-25 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_28875 2aba8ce2a9617f7f410f38ec66d15840 127 Pfam PF00072 Response regulator receiver domain 9 89 1.1E-16 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_28875 2aba8ce2a9617f7f410f38ec66d15840 127 Gene3D G3DSA:3.40.50.2300 2 127 9.9E-25 T 14-10-2018 TSH58p_25680 41ebb7be46b23fb013c45886f72f3b3c 417 Pfam PF03275 UDP-galactopyranose mutase 166 363 3.6E-81 T 14-10-2018 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 TSH58p_25680 41ebb7be46b23fb013c45886f72f3b3c 417 SUPERFAMILY SSF51971 21 383 3.18E-51 T 14-10-2018 TSH58p_25680 41ebb7be46b23fb013c45886f72f3b3c 417 Gene3D G3DSA:3.40.50.720 170 282 5.0E-27 T 14-10-2018 TSH58p_25680 41ebb7be46b23fb013c45886f72f3b3c 417 Pfam PF13450 NAD(P)-binding Rossmann-like domain 25 92 1.5E-16 T 14-10-2018 TSH58p_25680 41ebb7be46b23fb013c45886f72f3b3c 417 Gene3D G3DSA:3.40.50.720 18 114 3.7E-32 T 14-10-2018 TSH58p_25680 41ebb7be46b23fb013c45886f72f3b3c 417 Gene3D G3DSA:3.40.50.720 296 389 7.6E-21 T 14-10-2018 TSH58p_25680 41ebb7be46b23fb013c45886f72f3b3c 417 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 21 376 1.1E-118 T 14-10-2018 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 TSH58p_25680 41ebb7be46b23fb013c45886f72f3b3c 417 SUPERFAMILY SSF54373 265 330 2.55E-21 T 14-10-2018 TSH58p_03805 3a2b9990655bd9bb1df27aef93e46d72 265 PIRSF PIRSF002936 204 265 3.1E-16 T 14-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 TSH58p_03805 3a2b9990655bd9bb1df27aef93e46d72 265 PIRSF PIRSF002936 1 207 1.2E-78 T 14-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 TSH58p_03805 3a2b9990655bd9bb1df27aef93e46d72 265 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 26 217 1.0E-34 T 14-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 TSH58p_03805 3a2b9990655bd9bb1df27aef93e46d72 265 Gene3D G3DSA:3.40.50.620 3 204 8.4E-53 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_03805 3a2b9990655bd9bb1df27aef93e46d72 265 SUPERFAMILY SSF52402 4 202 4.97E-54 T 14-10-2018 TSH58p_27835 1c849c8e2f48cf785fc222793d177289 294 Pfam PF01418 Helix-turn-helix domain, rpiR family 6 77 7.3E-22 T 14-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 TSH58p_27835 1c849c8e2f48cf785fc222793d177289 294 SUPERFAMILY SSF46689 5 82 2.15E-20 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_27835 1c849c8e2f48cf785fc222793d177289 294 Pfam PF01380 SIS domain 128 254 1.1E-12 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TSH58p_27835 1c849c8e2f48cf785fc222793d177289 294 SUPERFAMILY SSF53697 98 268 6.45E-33 T 14-10-2018 TSH58p_27835 1c849c8e2f48cf785fc222793d177289 294 Gene3D G3DSA:3.40.50.10490 95 280 1.4E-35 T 14-10-2018 TSH58p_27835 1c849c8e2f48cf785fc222793d177289 294 Gene3D G3DSA:1.10.10.10 3 82 6.8E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_02620 c2e12a531617f308a271cb546928871c 224 Pfam PF03264 NapC/NirT cytochrome c family, N-terminal region 18 191 7.4E-76 T 14-10-2018 IPR005126 NapC/NirT cytochrome c, N-terminal TSH58p_02620 c2e12a531617f308a271cb546928871c 224 PIRSF PIRSF000013 1 201 5.0E-107 T 14-10-2018 IPR024717 Denitrification system component NapC/NirT/NrfH GO:0016021|GO:0019333|GO:0020037 TSH58p_02620 c2e12a531617f308a271cb546928871c 224 Gene3D G3DSA:1.10.3820.10 19 193 5.4E-38 T 14-10-2018 IPR038266 NapC/NirT cytochrome c superfamily TSH58p_02620 c2e12a531617f308a271cb546928871c 224 SUPERFAMILY SSF48695 17 194 1.44E-63 T 14-10-2018 IPR036280 Multiheme cytochrome superfamily TSH58p_02620 c2e12a531617f308a271cb546928871c 224 TIGRFAM TIGR02161 napC_nirT: periplasmic nitrate (or nitrite) reductase c-type cytochrome, NapC/NirT family 9 191 1.0E-96 T 14-10-2018 IPR011885 Periplasmic nitrate reductase c-type cytochrome, NapC/NirT GO:0016021|GO:0019333|GO:0020037 TSH58p_09200 8abec830d1b0c330ff374ceef14cb298 125 SUPERFAMILY SSF56399 5 113 3.16E-37 T 14-10-2018 TSH58p_09200 8abec830d1b0c330ff374ceef14cb298 125 Pfam PF06108 Protein of unknown function (DUF952) 10 97 3.6E-31 T 14-10-2018 IPR009297 Protein of unknown function DUF952 TSH58p_09200 8abec830d1b0c330ff374ceef14cb298 125 Gene3D G3DSA:3.20.170.20 4 116 5.1E-38 T 14-10-2018 TSH58p_08310 240d7ac835c38f5df9a2079e4a0e3570 267 Gene3D G3DSA:3.40.190.10 128 219 4.6E-55 T 14-10-2018 TSH58p_08310 240d7ac835c38f5df9a2079e4a0e3570 267 SUPERFAMILY SSF53850 14 261 4.19E-52 T 14-10-2018 TSH58p_08310 240d7ac835c38f5df9a2079e4a0e3570 267 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 42 259 1.5E-49 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_08310 240d7ac835c38f5df9a2079e4a0e3570 267 SMART SM00062 41 261 5.0E-44 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_08310 240d7ac835c38f5df9a2079e4a0e3570 267 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 64 77 - T 14-10-2018 IPR018313 Solute-binding protein family 3, conserved site TSH58p_08310 240d7ac835c38f5df9a2079e4a0e3570 267 Gene3D G3DSA:3.40.190.10 39 253 4.6E-55 T 14-10-2018 TSH58p_07405 5d2824f30c0ef8623f5662232409b587 364 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 233 251 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_07405 5d2824f30c0ef8623f5662232409b587 364 SUPERFAMILY SSF141072 72 185 1.03E-20 T 14-10-2018 IPR038081 CalX-like domain superfamily TSH58p_07405 5d2824f30c0ef8623f5662232409b587 364 Pfam PF03160 Calx-beta domain 60 162 7.2E-7 T 14-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 TSH58p_07405 5d2824f30c0ef8623f5662232409b587 364 Pfam PF03160 Calx-beta domain 12 47 1.3 T 14-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 TSH58p_07405 5d2824f30c0ef8623f5662232409b587 364 SUPERFAMILY SSF51120 110 327 2.09E-12 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_07405 5d2824f30c0ef8623f5662232409b587 364 Gene3D G3DSA:2.60.40.2030 74 207 1.3E-16 T 14-10-2018 IPR038081 CalX-like domain superfamily TSH58p_07405 5d2824f30c0ef8623f5662232409b587 364 Gene3D G3DSA:2.150.10.10 215 350 5.8E-14 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_07405 5d2824f30c0ef8623f5662232409b587 364 SMART SM00237 59 163 0.0059 T 14-10-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 TSH58p_07405 5d2824f30c0ef8623f5662232409b587 364 Gene3D G3DSA:2.60.40.2030 2 68 1.9E-10 T 14-10-2018 IPR038081 CalX-like domain superfamily TSH58p_07405 5d2824f30c0ef8623f5662232409b587 364 SUPERFAMILY SSF141072 4 72 4.05E-14 T 14-10-2018 IPR038081 CalX-like domain superfamily TSH58p_29520 5ec14a452ac7b3579fae2d2b66354b9b 221 Gene3D G3DSA:1.10.530.10 42 193 6.5E-11 T 14-10-2018 TSH58p_29520 5ec14a452ac7b3579fae2d2b66354b9b 221 Pfam PF01464 Transglycosylase SLT domain 46 168 2.8E-8 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 TSH58p_29520 5ec14a452ac7b3579fae2d2b66354b9b 221 SUPERFAMILY SSF53955 29 180 2.33E-17 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily TSH58p_06625 59d6043c1627a453fbbc5a1b5ac59f60 235 TIGRFAM TIGR02396 diverge_rpsU: rpsU-divergently transcribed protein 14 193 3.6E-48 T 14-10-2018 IPR012762 Ubiquinone biosynthesis protein COQ9 GO:0006744 Reactome: R-HSA-2142789 TSH58p_06625 59d6043c1627a453fbbc5a1b5ac59f60 235 Pfam PF08511 COQ9 115 191 2.5E-31 T 14-10-2018 IPR013718 COQ9 Reactome: R-HSA-2142789 TSH58p_06625 59d6043c1627a453fbbc5a1b5ac59f60 235 SUPERFAMILY SSF48498 85 186 6.67E-5 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TSH58p_06625 59d6043c1627a453fbbc5a1b5ac59f60 235 Gene3D G3DSA:1.10.357.10 4 186 1.3E-39 T 14-10-2018 TSH58p_07235 345a7925d4ec5fb51b9330f061d0e153 428 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 42 389 7.4E-58 T 14-10-2018 IPR006427 Phage portal protein, HK97 TSH58p_07235 345a7925d4ec5fb51b9330f061d0e153 428 Pfam PF04860 Phage portal protein 52 383 1.4E-77 T 14-10-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein TSH58p_10540 84ac909f13c138d0bcaaad882dcb2378 480 Gene3D G3DSA:1.10.260.40 4 80 3.3E-14 T 14-10-2018 TSH58p_10540 84ac909f13c138d0bcaaad882dcb2378 480 Pfam PF12844 Helix-turn-helix domain 10 67 1.1E-10 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_10540 84ac909f13c138d0bcaaad882dcb2378 480 PIRSF PIRSF019251 1 476 8.8E-195 T 14-10-2018 IPR026281 HTH-type transcriptional regulator RamB GO:0006355 TSH58p_10540 84ac909f13c138d0bcaaad882dcb2378 480 SUPERFAMILY SSF47413 4 70 2.39E-14 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_10540 84ac909f13c138d0bcaaad882dcb2378 480 SMART SM00530 10 65 1.3E-12 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_10540 84ac909f13c138d0bcaaad882dcb2378 480 Pfam PF09856 Predicted transcriptional regulator (DUF2083) 316 472 5.6E-69 T 14-10-2018 IPR018653 Domain of unknown function DUF2083,transcriptional regulator TSH58p_10540 84ac909f13c138d0bcaaad882dcb2378 480 Pfam PF06114 IrrE N-terminal-like domain 193 315 7.7E-17 T 14-10-2018 IPR010359 IrrE N-terminal-like domain TSH58p_01190 0f293bf4d40d54ece01a62c4cdfce51c 331 Pfam PF08544 GHMP kinases C terminal 215 299 4.4E-6 T 14-10-2018 IPR013750 GHMP kinase, C-terminal domain TSH58p_01190 0f293bf4d40d54ece01a62c4cdfce51c 331 Pfam PF00288 GHMP kinases N terminal domain 85 138 6.2E-6 T 14-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TSH58p_01190 0f293bf4d40d54ece01a62c4cdfce51c 331 SUPERFAMILY SSF54211 11 154 5.16E-19 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSH58p_01190 0f293bf4d40d54ece01a62c4cdfce51c 331 TIGRFAM TIGR00144 beta_RFAP_syn: beta-ribofuranosylaminobenzene 5'-phosphate synthase family 12 291 7.5E-47 T 14-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 TSH58p_01190 0f293bf4d40d54ece01a62c4cdfce51c 331 PIRSF PIRSF004884 7 322 7.8E-86 T 14-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 TSH58p_01190 0f293bf4d40d54ece01a62c4cdfce51c 331 Gene3D G3DSA:3.30.230.10 9 149 2.1E-10 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSH58p_13720 35bab1c98dac18f2f98a1fec76069e9f 426 Pfam PF00171 Aldehyde dehydrogenase family 8 289 1.1E-18 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TSH58p_13720 35bab1c98dac18f2f98a1fec76069e9f 426 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 332 353 - T 14-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 TSH58p_13720 35bab1c98dac18f2f98a1fec76069e9f 426 Gene3D G3DSA:3.40.605.10 22 422 8.0E-160 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TSH58p_13720 35bab1c98dac18f2f98a1fec76069e9f 426 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 14 425 40.497 T 14-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 TSH58p_13720 35bab1c98dac18f2f98a1fec76069e9f 426 Gene3D G3DSA:3.40.309.10 235 383 8.0E-160 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TSH58p_13720 35bab1c98dac18f2f98a1fec76069e9f 426 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 22 415 8.1E-140 T 14-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 TSH58p_13720 35bab1c98dac18f2f98a1fec76069e9f 426 SUPERFAMILY SSF53720 14 425 6.54E-119 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSH58p_13720 35bab1c98dac18f2f98a1fec76069e9f 426 PIRSF PIRSF000151 7 426 2.3E-170 T 14-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 TSH58p_22170 8967f0408ad933cc37bf69a0c204a089 150 Gene3D G3DSA:2.30.30.240 26 119 3.1E-5 T 14-10-2018 TSH58p_28545 bd7a1ae175febfeb48fa0566c42c3e28 249 SUPERFAMILY SSF52172 10 126 1.18E-33 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_28545 bd7a1ae175febfeb48fa0566c42c3e28 249 SUPERFAMILY SSF46894 145 245 2.98E-20 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_28545 bd7a1ae175febfeb48fa0566c42c3e28 249 Pfam PF00072 Response regulator receiver domain 12 119 6.2E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_28545 bd7a1ae175febfeb48fa0566c42c3e28 249 SMART SM00862 167 244 3.3E-18 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_28545 bd7a1ae175febfeb48fa0566c42c3e28 249 Pfam PF00486 Transcriptional regulatory protein, C terminal 170 244 1.9E-17 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_28545 bd7a1ae175febfeb48fa0566c42c3e28 249 Gene3D G3DSA:1.10.10.10 135 248 1.0E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_28545 bd7a1ae175febfeb48fa0566c42c3e28 249 Gene3D G3DSA:3.40.50.2300 6 129 8.3E-32 T 14-10-2018 TSH58p_28545 bd7a1ae175febfeb48fa0566c42c3e28 249 SMART SM00448 10 119 5.4E-34 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_19470 c08717aebf00ba6dc9546eba0bc6db82 423 PIRSF PIRSF039004 2 420 9.1E-115 T 14-10-2018 IPR020043 Deacetylase Atu3266-like GO:0019213 TSH58p_19470 c08717aebf00ba6dc9546eba0bc6db82 423 Pfam PF01979 Amidohydrolase family 333 375 5.9E-6 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TSH58p_19470 c08717aebf00ba6dc9546eba0bc6db82 423 Gene3D G3DSA:3.20.20.140 62 360 4.4E-86 T 14-10-2018 TSH58p_19470 c08717aebf00ba6dc9546eba0bc6db82 423 Gene3D G3DSA:2.30.40.10 17 405 4.4E-86 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_19470 c08717aebf00ba6dc9546eba0bc6db82 423 SUPERFAMILY SSF51556 62 357 5.26E-42 T 14-10-2018 IPR032466 Metal-dependent hydrolase TSH58p_19470 c08717aebf00ba6dc9546eba0bc6db82 423 SUPERFAMILY SSF51338 3 376 5.23E-17 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_00565 eb71f379f57e76b0fbdcb3d1baa470fc 444 Pfam PF00232 Glycosyl hydrolase family 1 5 438 8.5E-142 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSH58p_00565 eb71f379f57e76b0fbdcb3d1baa470fc 444 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 10 24 - T 14-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site TSH58p_00565 eb71f379f57e76b0fbdcb3d1baa470fc 444 SUPERFAMILY SSF51445 3 438 1.41E-151 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_00565 eb71f379f57e76b0fbdcb3d1baa470fc 444 PRINTS PR00131 Glycosyl hydrolase family 1 signature 386 403 6.3E-19 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSH58p_00565 eb71f379f57e76b0fbdcb3d1baa470fc 444 PRINTS PR00131 Glycosyl hydrolase family 1 signature 365 376 6.3E-19 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSH58p_00565 eb71f379f57e76b0fbdcb3d1baa470fc 444 PRINTS PR00131 Glycosyl hydrolase family 1 signature 410 422 6.3E-19 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSH58p_00565 eb71f379f57e76b0fbdcb3d1baa470fc 444 PRINTS PR00131 Glycosyl hydrolase family 1 signature 282 296 6.3E-19 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSH58p_00565 eb71f379f57e76b0fbdcb3d1baa470fc 444 PRINTS PR00131 Glycosyl hydrolase family 1 signature 344 352 6.3E-19 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TSH58p_00565 eb71f379f57e76b0fbdcb3d1baa470fc 444 TIGRFAM TIGR03356 BGL: beta-galactosidase 6 431 1.8E-174 T 14-10-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092|MetaCyc: PWY-7913 TSH58p_00565 eb71f379f57e76b0fbdcb3d1baa470fc 444 Gene3D G3DSA:3.20.20.80 2 443 2.4E-159 T 14-10-2018 TSH58p_29675 fb7d44a53a8695762e7c4b88891d3f61 723 SUPERFAMILY SSF109604 6 191 4.87E-70 T 14-10-2018 TSH58p_29675 fb7d44a53a8695762e7c4b88891d3f61 723 SUPERFAMILY SSF81301 182 392 2.62E-59 T 14-10-2018 TSH58p_29675 fb7d44a53a8695762e7c4b88891d3f61 723 SUPERFAMILY SSF81271 375 448 6.32E-23 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 TSH58p_29675 fb7d44a53a8695762e7c4b88891d3f61 723 Gene3D G3DSA:1.10.3210.10 1 192 9.6E-78 T 14-10-2018 TSH58p_29675 fb7d44a53a8695762e7c4b88891d3f61 723 Pfam PF04607 Region found in RelA / SpoT proteins 237 347 2.6E-35 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 TSH58p_29675 fb7d44a53a8695762e7c4b88891d3f61 723 Gene3D G3DSA:3.10.20.30 381 453 8.2E-34 T 14-10-2018 IPR012675 Beta-grasp domain superfamily TSH58p_29675 fb7d44a53a8695762e7c4b88891d3f61 723 SMART SM00471 41 153 1.8E-8 T 14-10-2018 IPR003607 HD/PDEase domain TSH58p_29675 fb7d44a53a8695762e7c4b88891d3f61 723 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 26 715 3.3E-219 T 14-10-2018 IPR004811 RelA/SpoT family GO:0015969 TSH58p_29675 fb7d44a53a8695762e7c4b88891d3f61 723 SUPERFAMILY SSF55021 646 717 8.02E-9 T 14-10-2018 TSH58p_29675 fb7d44a53a8695762e7c4b88891d3f61 723 Gene3D G3DSA:3.30.460.10 195 327 3.6E-44 T 14-10-2018 TSH58p_29675 fb7d44a53a8695762e7c4b88891d3f61 723 Pfam PF13328 HD domain 26 176 8.7E-49 T 14-10-2018 IPR003607 HD/PDEase domain TSH58p_29675 fb7d44a53a8695762e7c4b88891d3f61 723 SMART SM00954 237 347 1.6E-62 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 TSH58p_29675 fb7d44a53a8695762e7c4b88891d3f61 723 Pfam PF02824 TGS domain 389 447 6.9E-20 T 14-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 TSH58p_29675 fb7d44a53a8695762e7c4b88891d3f61 723 Gene3D G3DSA:3.30.70.260 646 722 2.9E-12 T 14-10-2018 TSH58p_29675 fb7d44a53a8695762e7c4b88891d3f61 723 Pfam PF13291 ACT domain 645 719 6.1E-18 T 14-10-2018 IPR002912 ACT domain TSH58p_25055 3fb274b0997255f01bb019f4916e056b 337 Gene3D G3DSA:3.90.1200.10 116 275 3.8E-7 T 14-10-2018 TSH58p_25055 3fb274b0997255f01bb019f4916e056b 337 SUPERFAMILY SSF56112 26 297 6.76E-19 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily TSH58p_02885 d2e80b065bcc67fe480adc8d826eda8a 295 SUPERFAMILY SSF52172 75 199 3.56E-9 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_02885 d2e80b065bcc67fe480adc8d826eda8a 295 SMART SM00421 233 290 2.8E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_02885 d2e80b065bcc67fe480adc8d826eda8a 295 Gene3D G3DSA:1.10.10.10 226 295 7.5E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_02885 d2e80b065bcc67fe480adc8d826eda8a 295 Gene3D G3DSA:3.40.50.2300 70 198 6.2E-8 T 14-10-2018 TSH58p_02885 d2e80b065bcc67fe480adc8d826eda8a 295 ProSitePatterns PS00622 LuxR-type HTH domain signature. 250 277 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_02885 d2e80b065bcc67fe480adc8d826eda8a 295 Pfam PF00196 Bacterial regulatory proteins, luxR family 235 288 2.6E-18 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_02885 d2e80b065bcc67fe480adc8d826eda8a 295 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 266 278 7.4E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_02885 d2e80b065bcc67fe480adc8d826eda8a 295 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 236 250 7.4E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_02885 d2e80b065bcc67fe480adc8d826eda8a 295 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 250 266 7.4E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_02885 d2e80b065bcc67fe480adc8d826eda8a 295 SUPERFAMILY SSF46894 226 292 4.42E-18 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_06520 6e4a68d33ebba71aa5a48d0686f36214 587 SUPERFAMILY SSF52518 2 186 1.15E-64 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_06520 6e4a68d33ebba71aa5a48d0686f36214 587 SUPERFAMILY SSF52467 189 364 7.12E-64 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TSH58p_06520 6e4a68d33ebba71aa5a48d0686f36214 587 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 7 170 8.5E-58 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 TSH58p_06520 6e4a68d33ebba71aa5a48d0686f36214 587 Gene3D G3DSA:3.40.50.1220 190 362 7.3E-60 T 14-10-2018 TSH58p_06520 6e4a68d33ebba71aa5a48d0686f36214 587 Gene3D G3DSA:3.40.50.970 366 575 3.4E-68 T 14-10-2018 TSH58p_06520 6e4a68d33ebba71aa5a48d0686f36214 587 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 398 546 3.6E-48 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TSH58p_06520 6e4a68d33ebba71aa5a48d0686f36214 587 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 6 568 2.6E-240 T 14-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 TSH58p_06520 6e4a68d33ebba71aa5a48d0686f36214 587 SUPERFAMILY SSF52518 374 572 2.86E-68 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_06520 6e4a68d33ebba71aa5a48d0686f36214 587 Gene3D G3DSA:3.40.50.970 1 182 1.8E-70 T 14-10-2018 TSH58p_06520 6e4a68d33ebba71aa5a48d0686f36214 587 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 196 332 2.5E-43 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 TSH58p_04915 41cbd42e63407f9b929f2c21dc500125 155 SUPERFAMILY SSF47413 20 93 9.21E-28 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_04915 41cbd42e63407f9b929f2c21dc500125 155 Pfam PF01381 Helix-turn-helix 32 86 5.2E-14 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_04915 41cbd42e63407f9b929f2c21dc500125 155 Gene3D G3DSA:1.10.260.40 23 91 5.5E-18 T 14-10-2018 TSH58p_04915 41cbd42e63407f9b929f2c21dc500125 155 SMART SM00530 31 86 2.0E-14 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_24220 e091f2d8e8917a515f7910e6e76dcf91 80 SMART SM00834 1 47 0.0018 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain TSH58p_24220 e091f2d8e8917a515f7910e6e76dcf91 80 Pfam PF06676 Protein of unknown function (DUF1178) 1 62 5.2E-19 T 14-10-2018 IPR009562 Protein of unknown function DUF1178 TSH58p_26870 f2be0f3a011b7195f6bc25f883e03c36 315 Gene3D G3DSA:1.10.3720.10 87 310 6.8E-22 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_26870 f2be0f3a011b7195f6bc25f883e03c36 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 313 1.7E-43 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_26870 f2be0f3a011b7195f6bc25f883e03c36 315 SUPERFAMILY SSF161098 92 299 2.45E-19 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_08630 6dc16625bb6509270149adc78ef82b5f 1008 Pfam PF00912 Transglycosylase 130 334 1.0E-24 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_08630 6dc16625bb6509270149adc78ef82b5f 1008 Gene3D G3DSA:1.10.3810.10 120 357 1.6E-5 T 14-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_08630 6dc16625bb6509270149adc78ef82b5f 1008 Gene3D G3DSA:3.40.710.10 782 1005 5.2E-15 T 14-10-2018 TSH58p_08630 6dc16625bb6509270149adc78ef82b5f 1008 SUPERFAMILY SSF56601 718 993 3.68E-26 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TSH58p_08630 6dc16625bb6509270149adc78ef82b5f 1008 SUPERFAMILY SSF53955 137 353 2.62E-7 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily TSH58p_06775 7db564f725643a1e880e24d945aca236 339 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 337 45.385 T 14-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 TSH58p_06775 7db564f725643a1e880e24d945aca236 339 SUPERFAMILY SSF111337 1 336 3.27E-127 T 14-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 TSH58p_06775 7db564f725643a1e880e24d945aca236 339 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 335 2.2E-116 T 14-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 TSH58p_06775 7db564f725643a1e880e24d945aca236 339 Gene3D G3DSA:3.40.1780.10 15 335 2.8E-112 T 14-10-2018 TSH58p_06775 7db564f725643a1e880e24d945aca236 339 Pfam PF02547 Queuosine biosynthesis protein 4 336 7.7E-130 T 14-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 TSH58p_06775 7db564f725643a1e880e24d945aca236 339 Gene3D G3DSA:2.40.10.240 61 158 2.8E-112 T 14-10-2018 TSH58p_24470 09c01bdb4dc1b8073544cc91ed9c0b63 142 Gene3D G3DSA:1.20.1290.10 2 135 4.6E-40 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TSH58p_24470 09c01bdb4dc1b8073544cc91ed9c0b63 142 SUPERFAMILY SSF69118 11 133 1.03E-34 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TSH58p_24470 09c01bdb4dc1b8073544cc91ed9c0b63 142 Pfam PF02627 Carboxymuconolactone decarboxylase family 43 128 8.3E-22 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TSH58p_07120 4e800e3230ef73bb812da5cef04c2cba 581 SUPERFAMILY SSF52540 329 562 6.31E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_07120 4e800e3230ef73bb812da5cef04c2cba 581 Gene3D G3DSA:1.20.1560.10 17 321 3.2E-28 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_07120 4e800e3230ef73bb812da5cef04c2cba 581 Pfam PF00664 ABC transporter transmembrane region 32 287 6.4E-11 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TSH58p_07120 4e800e3230ef73bb812da5cef04c2cba 581 SMART SM00382 363 549 6.0E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_07120 4e800e3230ef73bb812da5cef04c2cba 581 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_07120 4e800e3230ef73bb812da5cef04c2cba 581 TIGRFAM TIGR01842 type_I_sec_PrtD: type I secretion system ATPase 27 562 5.1E-176 T 14-10-2018 IPR010128 ATPase, type I secretion system, PrtD GO:0005524|GO:0008565|GO:0016021|GO:0030253|GO:0030256 TSH58p_07120 4e800e3230ef73bb812da5cef04c2cba 581 Gene3D G3DSA:3.40.50.300 334 571 1.0E-66 T 14-10-2018 TSH58p_07120 4e800e3230ef73bb812da5cef04c2cba 581 SUPERFAMILY SSF90123 23 324 5.89E-35 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_07120 4e800e3230ef73bb812da5cef04c2cba 581 Pfam PF00005 ABC transporter 354 501 1.8E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_12125 44ac6955d0d3d00c2c31d2d2d28dec1d 559 Gene3D G3DSA:3.30.70.1450 302 374 1.2E-9 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSH58p_12125 44ac6955d0d3d00c2c31d2d2d28dec1d 559 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 389 542 1.2E-45 T 14-10-2018 IPR006512 YidE/YbjL duplication TSH58p_12125 44ac6955d0d3d00c2c31d2d2d28dec1d 559 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 28 176 3.3E-34 T 14-10-2018 IPR006512 YidE/YbjL duplication TSH58p_12125 44ac6955d0d3d00c2c31d2d2d28dec1d 559 Gene3D G3DSA:3.30.70.1450 207 285 2.0E-9 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSH58p_12125 44ac6955d0d3d00c2c31d2d2d28dec1d 559 SUPERFAMILY SSF116726 217 285 4.05E-11 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSH58p_12125 44ac6955d0d3d00c2c31d2d2d28dec1d 559 Pfam PF06826 Predicted Permease Membrane Region 384 555 5.9E-45 T 14-10-2018 IPR006512 YidE/YbjL duplication TSH58p_12125 44ac6955d0d3d00c2c31d2d2d28dec1d 559 Pfam PF06826 Predicted Permease Membrane Region 21 189 3.2E-40 T 14-10-2018 IPR006512 YidE/YbjL duplication TSH58p_12125 44ac6955d0d3d00c2c31d2d2d28dec1d 559 Pfam PF02080 TrkA-C domain 305 370 3.9E-11 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TSH58p_12125 44ac6955d0d3d00c2c31d2d2d28dec1d 559 Pfam PF02080 TrkA-C domain 221 285 1.2E-8 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TSH58p_12125 44ac6955d0d3d00c2c31d2d2d28dec1d 559 SUPERFAMILY SSF116726 296 370 1.44E-12 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 Gene3D G3DSA:1.25.40.10 631 903 7.8E-49 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 SMART SM00028 728 761 3.9E-6 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 SMART SM00028 84 117 0.59 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 SMART SM00028 660 693 0.015 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 SMART SM00028 796 829 1.1E-5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 SMART SM00028 220 253 1.5E-5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 SMART SM00028 186 219 0.13 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 SMART SM00028 16 49 0.047 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 SMART SM00028 254 287 0.019 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 SMART SM00028 152 185 9.2E-5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 SMART SM00028 830 863 7.6 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 SMART SM00028 762 795 320.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 SMART SM00028 694 727 0.062 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 SMART SM00028 288 321 1.0E-7 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 SMART SM00028 118 151 13.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 SMART SM00028 50 83 110.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 SUPERFAMILY SSF48452 8 130 3.85E-18 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 SUPERFAMILY SSF53756 915 1164 1.66E-11 T 14-10-2018 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 Pfam PF00515 Tetratricopeptide repeat 729 761 2.8E-7 T 14-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 Pfam PF00515 Tetratricopeptide repeat 797 828 1.1E-6 T 14-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 Pfam PF00515 Tetratricopeptide repeat 289 320 1.5E-8 T 14-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 Gene3D G3DSA:1.25.40.10 8 159 2.4E-26 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 Gene3D G3DSA:1.25.40.10 160 194 6.7E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 Gene3D G3DSA:1.25.40.10 195 228 4.4E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 Pfam PF13432 Tetratricopeptide repeat 667 726 5.3E-8 T 14-10-2018 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 Pfam PF13432 Tetratricopeptide repeat 28 80 1.6E-7 T 14-10-2018 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 Pfam PF13432 Tetratricopeptide repeat 156 220 4.0E-8 T 14-10-2018 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 Pfam PF13424 Tetratricopeptide repeat 221 278 4.9E-8 T 14-10-2018 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 SUPERFAMILY SSF53756 373 623 1.85E-9 T 14-10-2018 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 Gene3D G3DSA:1.25.40.10 229 292 3.0E-15 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 SUPERFAMILY SSF48452 656 876 2.28E-35 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 Gene3D G3DSA:1.25.40.10 293 366 2.9E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29255 d5a032f446b9c93c42474dafe354a3ec 1190 SUPERFAMILY SSF48452 137 348 1.58E-42 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_32565 f9088f2458fe4d0084bea5964dfe51a8 117 Pfam PF07746 Aromatic-ring-opening dioxygenase LigAB, LigA subunit 27 112 3.1E-36 T 14-10-2018 IPR011986 Extradiol ring-cleavage dioxygenase LigAB, LigA subunit TSH58p_32565 f9088f2458fe4d0084bea5964dfe51a8 117 SUPERFAMILY SSF48076 6 116 7.45E-40 T 14-10-2018 IPR036622 Dioxygenase LigAB, LigA subunit superfamily TSH58p_32565 f9088f2458fe4d0084bea5964dfe51a8 117 Gene3D G3DSA:1.10.700.10 3 117 2.3E-45 T 14-10-2018 IPR036622 Dioxygenase LigAB, LigA subunit superfamily TSH58p_28405 852fd1998472697e13c2e358ea9bd007 513 Gene3D G3DSA:1.10.3210.10 309 503 4.8E-54 T 14-10-2018 TSH58p_28405 852fd1998472697e13c2e358ea9bd007 513 SUPERFAMILY SSF109604 350 480 2.2E-14 T 14-10-2018 TSH58p_28405 852fd1998472697e13c2e358ea9bd007 513 Gene3D G3DSA:3.30.420.150 124 308 3.0E-49 T 14-10-2018 TSH58p_28405 852fd1998472697e13c2e358ea9bd007 513 Gene3D G3DSA:3.30.420.40 5 123 6.3E-36 T 14-10-2018 TSH58p_28405 852fd1998472697e13c2e358ea9bd007 513 SUPERFAMILY SSF53067 18 140 4.21E-36 T 14-10-2018 TSH58p_28405 852fd1998472697e13c2e358ea9bd007 513 Pfam PF02541 Ppx/GppA phosphatase family 36 310 4.6E-43 T 14-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 TSH58p_28405 852fd1998472697e13c2e358ea9bd007 513 SUPERFAMILY SSF53067 142 312 2.29E-31 T 14-10-2018 TSH58p_30695 0fd0f31be6c2768009d87f5a8b02bbac 294 Gene3D G3DSA:3.40.190.10 205 247 3.5E-7 T 14-10-2018 TSH58p_30695 0fd0f31be6c2768009d87f5a8b02bbac 294 Gene3D G3DSA:1.10.10.10 4 90 2.1E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_30695 0fd0f31be6c2768009d87f5a8b02bbac 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 4.6E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_30695 0fd0f31be6c2768009d87f5a8b02bbac 294 SUPERFAMILY SSF46785 4 117 3.41E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_30695 0fd0f31be6c2768009d87f5a8b02bbac 294 Gene3D G3DSA:3.40.190.10 248 275 3.5E-7 T 14-10-2018 TSH58p_30695 0fd0f31be6c2768009d87f5a8b02bbac 294 Pfam PF03466 LysR substrate binding domain 93 276 1.9E-29 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_30695 0fd0f31be6c2768009d87f5a8b02bbac 294 SUPERFAMILY SSF53850 94 280 1.81E-34 T 14-10-2018 TSH58p_30695 0fd0f31be6c2768009d87f5a8b02bbac 294 Gene3D G3DSA:3.40.190.10 96 183 1.3E-22 T 14-10-2018 TSH58p_20580 c2f904944ffa8b93f031b6c8ed4dd431 216 Pfam PF14681 Uracil phosphoribosyltransferase 13 215 3.5E-72 T 14-10-2018 TSH58p_20580 c2f904944ffa8b93f031b6c8ed4dd431 216 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 11 215 2.9E-80 T 14-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 TSH58p_20580 c2f904944ffa8b93f031b6c8ed4dd431 216 Gene3D G3DSA:3.40.50.2020 7 216 2.1E-76 T 14-10-2018 TSH58p_20580 c2f904944ffa8b93f031b6c8ed4dd431 216 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 10 216 44.215 T 14-10-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 TSH58p_20580 c2f904944ffa8b93f031b6c8ed4dd431 216 SUPERFAMILY SSF53271 11 214 8.78E-69 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like TSH58p_22295 e9bd2e547edc28125263873daaa7da02 152 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 38 131 2.7E-15 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_22295 e9bd2e547edc28125263873daaa7da02 152 Gene3D G3DSA:1.10.760.10 24 139 7.1E-22 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_22295 e9bd2e547edc28125263873daaa7da02 152 SUPERFAMILY SSF46626 31 138 8.09E-24 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_21375 816b0339307669981998791fb43bf3db 358 Pfam PF13407 Periplasmic binding protein domain 34 309 1.1E-63 T 14-10-2018 IPR025997 Periplasmic binding protein TSH58p_21375 816b0339307669981998791fb43bf3db 358 Gene3D G3DSA:3.40.50.2300 136 352 1.5E-133 T 14-10-2018 TSH58p_21375 816b0339307669981998791fb43bf3db 358 Gene3D G3DSA:3.40.50.2300 34 332 1.5E-133 T 14-10-2018 TSH58p_21375 816b0339307669981998791fb43bf3db 358 SUPERFAMILY SSF53822 31 344 2.36E-69 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_30835 e8798c01e912cb20a6ab2a66e44ec67d 166 Gene3D G3DSA:3.10.490.10 1 149 4.2E-14 T 14-10-2018 TSH58p_30835 e8798c01e912cb20a6ab2a66e44ec67d 166 SUPERFAMILY SSF110857 1 106 1.11E-5 T 14-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily TSH58p_30560 a153c9442ab1f72ca3162610a4d274f1 388 SUPERFAMILY SSF53383 2 382 8.51E-97 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_30560 a153c9442ab1f72ca3162610a4d274f1 388 Gene3D G3DSA:3.40.640.10 39 278 4.1E-120 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_30560 a153c9442ab1f72ca3162610a4d274f1 388 Pfam PF00155 Aminotransferase class I and II 27 367 7.2E-53 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSH58p_30560 a153c9442ab1f72ca3162610a4d274f1 388 Gene3D G3DSA:3.90.1150.10 14 378 4.1E-120 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_32590 461f8db85b4e9eb1eac8e3ca6c64d509 305 Pfam PF02311 AraC-like ligand binding domain 45 112 6.6E-5 T 14-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 TSH58p_32590 461f8db85b4e9eb1eac8e3ca6c64d509 305 SUPERFAMILY SSF46689 255 302 1.84E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_32590 461f8db85b4e9eb1eac8e3ca6c64d509 305 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 268 283 6.1E-6 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TSH58p_32590 461f8db85b4e9eb1eac8e3ca6c64d509 305 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 283 299 6.1E-6 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TSH58p_32590 461f8db85b4e9eb1eac8e3ca6c64d509 305 SUPERFAMILY SSF51182 48 131 9.78E-11 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_32590 461f8db85b4e9eb1eac8e3ca6c64d509 305 Pfam PF12833 Helix-turn-helix domain 222 300 2.4E-19 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TSH58p_32590 461f8db85b4e9eb1eac8e3ca6c64d509 305 Gene3D G3DSA:1.10.10.60 195 304 7.3E-24 T 14-10-2018 TSH58p_32590 461f8db85b4e9eb1eac8e3ca6c64d509 305 SMART SM00342 216 299 3.8E-21 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TSH58p_32590 461f8db85b4e9eb1eac8e3ca6c64d509 305 Gene3D G3DSA:2.60.120.10 44 129 3.6E-7 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_26525 3399134749e731d768f5f4ea5770d4a8 1001 Pfam PF13244 Domain of unknown function (DUF4040) 620 685 1.1E-20 T 14-10-2018 IPR025383 Domain of unknown function DUF4040 TSH58p_26525 3399134749e731d768f5f4ea5770d4a8 1001 Pfam PF00361 Proton-conducting membrane transporter 130 409 1.3E-60 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_26525 3399134749e731d768f5f4ea5770d4a8 1001 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 154 175 5.8E-38 T 14-10-2018 TSH58p_26525 3399134749e731d768f5f4ea5770d4a8 1001 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 242 268 5.8E-38 T 14-10-2018 TSH58p_26525 3399134749e731d768f5f4ea5770d4a8 1001 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 310 322 5.8E-38 T 14-10-2018 TSH58p_26525 3399134749e731d768f5f4ea5770d4a8 1001 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 79 104 5.8E-38 T 14-10-2018 TSH58p_26525 3399134749e731d768f5f4ea5770d4a8 1001 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 420 439 5.8E-38 T 14-10-2018 TSH58p_26525 3399134749e731d768f5f4ea5770d4a8 1001 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 107 127 5.8E-38 T 14-10-2018 TSH58p_26525 3399134749e731d768f5f4ea5770d4a8 1001 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 220 241 5.8E-38 T 14-10-2018 TSH58p_26525 3399134749e731d768f5f4ea5770d4a8 1001 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 821 943 7.5E-31 T 14-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein TSH58p_26525 3399134749e731d768f5f4ea5770d4a8 1001 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 65 117 2.1E-10 T 14-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_11445 c0a76c21baa918e4fd2719edb1c7924d 344 Pfam PF12544 Lysine-2,3-aminomutase 290 342 4.3E-6 T 14-10-2018 IPR025895 Lysine-2,3-aminomutase, C-terminal domain TSH58p_11445 c0a76c21baa918e4fd2719edb1c7924d 344 Pfam PF04055 Radical SAM superfamily 97 246 8.3E-11 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSH58p_11445 c0a76c21baa918e4fd2719edb1c7924d 344 Gene3D G3DSA:3.20.20.70 31 316 6.9E-96 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_11445 c0a76c21baa918e4fd2719edb1c7924d 344 Pfam PF13353 4Fe-4S single cluster domain 98 163 9.2E-5 T 14-10-2018 TSH58p_11445 c0a76c21baa918e4fd2719edb1c7924d 344 PIRSF PIRSF004911 1 344 3.9E-119 T 14-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase TSH58p_11445 c0a76c21baa918e4fd2719edb1c7924d 344 TIGRFAM TIGR00238 TIGR00238: KamA family protein 23 310 1.1E-78 T 14-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase TSH58p_11445 c0a76c21baa918e4fd2719edb1c7924d 344 SUPERFAMILY SSF102114 82 321 2.35E-33 T 14-10-2018 TSH58p_11445 c0a76c21baa918e4fd2719edb1c7924d 344 TIGRFAM TIGR03822 AblA_like_2: lysine-2,3-aminomutase-related protein 6 319 1.2E-149 T 14-10-2018 IPR022447 Lysine-2,3-aminomutase-related TSH58p_13160 cf500b034b2ee2726b84f3472e2505f0 266 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 33 238 3.0E-50 T 14-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TSH58p_13160 cf500b034b2ee2726b84f3472e2505f0 266 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 266 100.923 T 14-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TSH58p_13160 cf500b034b2ee2726b84f3472e2505f0 266 Gene3D G3DSA:1.10.1270.20 186 251 3.0E-26 T 14-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TSH58p_13160 cf500b034b2ee2726b84f3472e2505f0 266 SUPERFAMILY SSF75217 11 251 1.11E-88 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases TSH58p_13160 cf500b034b2ee2726b84f3472e2505f0 266 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 14 248 9.2E-79 T 14-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TSH58p_13160 cf500b034b2ee2726b84f3472e2505f0 266 Gene3D G3DSA:3.40.1280.10 11 185 1.6E-61 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TSH58p_13160 cf500b034b2ee2726b84f3472e2505f0 266 PIRSF PIRSF000386 11 261 1.2E-87 T 14-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TSH58p_15230 36b3cf5d6fb51d0db75a47899699ae70 101 Gene3D G3DSA:4.10.830.10 42 101 1.8E-24 T 14-10-2018 TSH58p_15230 36b3cf5d6fb51d0db75a47899699ae70 101 SUPERFAMILY SSF57716 2 101 1.19E-37 T 14-10-2018 TSH58p_15230 36b3cf5d6fb51d0db75a47899699ae70 101 ProSitePatterns PS00527 Ribosomal protein S14 signature. 63 85 - T 14-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15230 36b3cf5d6fb51d0db75a47899699ae70 101 Pfam PF00253 Ribosomal protein S14p/S29e 47 100 8.2E-26 T 14-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15230 36b3cf5d6fb51d0db75a47899699ae70 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 26.502 T 14-10-2018 IPR023036 Ribosomal protein S14, bacterial/plastid TSH58p_19975 dc2dce7e54ab12417b1f3c6e1ed555e3 383 SUPERFAMILY SSF52540 25 262 5.6E-90 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_19975 dc2dce7e54ab12417b1f3c6e1ed555e3 383 SMART SM00382 49 240 3.1E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_19975 dc2dce7e54ab12417b1f3c6e1ed555e3 383 Gene3D G3DSA:2.40.50.140 304 373 2.8E-10 T 14-10-2018 TSH58p_19975 dc2dce7e54ab12417b1f3c6e1ed555e3 383 Gene3D G3DSA:3.40.50.300 25 242 6.0E-73 T 14-10-2018 TSH58p_19975 dc2dce7e54ab12417b1f3c6e1ed555e3 383 SUPERFAMILY SSF50331 258 377 3.95E-11 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSH58p_19975 dc2dce7e54ab12417b1f3c6e1ed555e3 383 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_19975 dc2dce7e54ab12417b1f3c6e1ed555e3 383 Gene3D G3DSA:2.40.50.940 243 379 2.8E-10 T 14-10-2018 TSH58p_19975 dc2dce7e54ab12417b1f3c6e1ed555e3 383 Pfam PF00005 ABC transporter 40 182 1.0E-36 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_19975 dc2dce7e54ab12417b1f3c6e1ed555e3 383 Pfam PF08402 TOBE domain 298 381 6.6E-8 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TSH58p_27650 d6053d49584c15cdfe3aaf6c04a96921 102 Gene3D G3DSA:3.40.30.10 2 101 3.4E-39 T 14-10-2018 TSH58p_27650 d6053d49584c15cdfe3aaf6c04a96921 102 TIGRFAM TIGR02174 CXXU_selWTH: selT/selW/selH selenoprotein domain 11 82 7.6E-20 T 14-10-2018 IPR011893 Selenoprotein, Rdx-type TSH58p_27650 d6053d49584c15cdfe3aaf6c04a96921 102 Pfam PF10262 Rdx family 12 83 3.1E-31 T 14-10-2018 IPR011893 Selenoprotein, Rdx-type TSH58p_27650 d6053d49584c15cdfe3aaf6c04a96921 102 SUPERFAMILY SSF52833 9 92 5.37E-27 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_12545 acd67727474ee4cedcde8f0be0b16a37 218 Pfam PF07021 Methionine biosynthesis protein MetW 42 121 2.8E-6 T 14-10-2018 IPR010743 Methionine biosynthesis MetW KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 TSH58p_12545 acd67727474ee4cedcde8f0be0b16a37 218 Gene3D G3DSA:3.40.50.150 25 201 1.7E-18 T 14-10-2018 TSH58p_12545 acd67727474ee4cedcde8f0be0b16a37 218 SUPERFAMILY SSF53335 33 188 5.88E-21 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_00470 842e861854c070f07d21c745fe253bb1 260 Gene3D G3DSA:1.10.12.10 203 260 4.8E-21 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal TSH58p_00470 842e861854c070f07d21c745fe253bb1 260 SUPERFAMILY SSF52096 2 259 9.23E-75 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_00470 842e861854c070f07d21c745fe253bb1 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 259 1.9E-53 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TSH58p_00470 842e861854c070f07d21c745fe253bb1 260 Gene3D G3DSA:3.90.226.10 1 200 4.9E-63 T 14-10-2018 TSH58p_02770 d944fc71d739b3b2f2674c73142a8b61 536 Gene3D G3DSA:3.90.76.10 63 200 2.6E-131 T 14-10-2018 TSH58p_02770 d944fc71d739b3b2f2674c73142a8b61 536 Gene3D G3DSA:3.10.105.10 288 509 2.6E-131 T 14-10-2018 TSH58p_02770 d944fc71d739b3b2f2674c73142a8b61 536 Gene3D G3DSA:3.40.190.10 201 519 2.6E-131 T 14-10-2018 TSH58p_02770 d944fc71d739b3b2f2674c73142a8b61 536 PIRSF PIRSF002741 2 536 3.8E-158 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TSH58p_02770 d944fc71d739b3b2f2674c73142a8b61 536 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 82 436 1.2E-95 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain TSH58p_02770 d944fc71d739b3b2f2674c73142a8b61 536 SUPERFAMILY SSF53850 37 529 4.16E-139 T 14-10-2018 TSH58p_14525 a8242439a85c0f43d7c8c8c72039b861 396 Gene3D G3DSA:3.40.50.720 177 347 6.1E-122 T 14-10-2018 TSH58p_14525 a8242439a85c0f43d7c8c8c72039b861 396 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 153 8.4E-25 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TSH58p_14525 a8242439a85c0f43d7c8c8c72039b861 396 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 2.0E-10 T 14-10-2018 IPR027399 Alcohol dehydrogenase GroES-associated TSH58p_14525 a8242439a85c0f43d7c8c8c72039b861 396 SUPERFAMILY SSF51735 163 357 2.45E-58 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_14525 a8242439a85c0f43d7c8c8c72039b861 396 SUPERFAMILY SSF50129 1 186 1.13E-54 T 14-10-2018 IPR011032 GroES-like superfamily TSH58p_14525 a8242439a85c0f43d7c8c8c72039b861 396 Pfam PF00107 Zinc-binding dehydrogenase 196 265 2.6E-11 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TSH58p_14525 a8242439a85c0f43d7c8c8c72039b861 396 SMART SM00829 8 394 2.8E-4 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TSH58p_14525 a8242439a85c0f43d7c8c8c72039b861 396 Gene3D G3DSA:3.90.180.10 10 382 6.1E-122 T 14-10-2018 TSH58p_08825 1687e8eddd64f59e125662fd9043ed22 124 SUPERFAMILY SSF52172 1 118 2.7E-20 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_08825 1687e8eddd64f59e125662fd9043ed22 124 Gene3D G3DSA:3.40.50.2300 1 121 4.0E-20 T 14-10-2018 TSH58p_08825 1687e8eddd64f59e125662fd9043ed22 124 SMART SM00448 1 112 6.3E-10 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_08825 1687e8eddd64f59e125662fd9043ed22 124 Pfam PF00072 Response regulator receiver domain 1 111 6.5E-12 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_15990 950abf9a79556ed5baa580ed2953cf43 234 Gene3D G3DSA:1.10.1740.10 68 135 6.3E-24 T 14-10-2018 TSH58p_15990 950abf9a79556ed5baa580ed2953cf43 234 Gene3D G3DSA:1.10.10.10 164 228 5.6E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_15990 950abf9a79556ed5baa580ed2953cf43 234 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 77 224 2.3E-22 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TSH58p_15990 950abf9a79556ed5baa580ed2953cf43 234 Pfam PF04542 Sigma-70 region 2 77 142 2.5E-15 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_15990 950abf9a79556ed5baa580ed2953cf43 234 SUPERFAMILY SSF88659 165 226 4.11E-17 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSH58p_15990 950abf9a79556ed5baa580ed2953cf43 234 SUPERFAMILY SSF88946 73 147 7.46E-20 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_15990 950abf9a79556ed5baa580ed2953cf43 234 Pfam PF08281 Sigma-70, region 4 169 221 2.9E-17 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_21215 ee749824519a6a34d6357b244297f628 257 Pfam PF00226 DnaJ domain 207 238 2.4E-8 T 14-10-2018 IPR001623 DnaJ domain TSH58p_21215 ee749824519a6a34d6357b244297f628 257 Gene3D G3DSA:1.10.287.110 195 257 5.8E-25 T 14-10-2018 IPR036869 Chaperone J-domain superfamily TSH58p_21215 ee749824519a6a34d6357b244297f628 257 SMART SM00271 205 256 3.3E-9 T 14-10-2018 IPR001623 DnaJ domain TSH58p_21215 ee749824519a6a34d6357b244297f628 257 PRINTS PR00625 DnaJ domain signature 208 226 4.0E-5 T 14-10-2018 IPR001623 DnaJ domain TSH58p_21215 ee749824519a6a34d6357b244297f628 257 PRINTS PR00625 DnaJ domain signature 226 241 4.0E-5 T 14-10-2018 IPR001623 DnaJ domain TSH58p_21215 ee749824519a6a34d6357b244297f628 257 SUPERFAMILY SSF46565 201 255 9.55E-17 T 14-10-2018 IPR036869 Chaperone J-domain superfamily TSH58p_25745 30d9fb9d5763d87f6e11ca1dd1429a17 334 SUPERFAMILY SSF81342 112 323 7.06E-43 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 TSH58p_25745 30d9fb9d5763d87f6e11ca1dd1429a17 334 TIGRFAM TIGR01583 formate-DH-gamm: formate dehydrogenase, gamma subunit 117 317 2.1E-51 T 14-10-2018 IPR006471 Formate dehydrogenase, gamma subunit GO:0008863|GO:0009326|GO:0016021|GO:0045333 TSH58p_25745 30d9fb9d5763d87f6e11ca1dd1429a17 334 Gene3D G3DSA:1.20.950.20 111 327 1.3E-65 T 14-10-2018 TSH58p_25745 30d9fb9d5763d87f6e11ca1dd1429a17 334 Pfam PF01292 Prokaryotic cytochrome b561 118 297 7.9E-20 T 14-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 TSH58p_13045 e0bc20e0a1b3195626db875563c44268 252 SMART SM00342 158 241 1.3E-30 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TSH58p_13045 e0bc20e0a1b3195626db875563c44268 252 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 225 241 2.2E-6 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TSH58p_13045 e0bc20e0a1b3195626db875563c44268 252 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 210 225 2.2E-6 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TSH58p_13045 e0bc20e0a1b3195626db875563c44268 252 SUPERFAMILY SSF46689 195 245 6.72E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_13045 e0bc20e0a1b3195626db875563c44268 252 Pfam PF12833 Helix-turn-helix domain 164 243 1.2E-24 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TSH58p_13045 e0bc20e0a1b3195626db875563c44268 252 SUPERFAMILY SSF46689 142 191 1.61E-5 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_13045 e0bc20e0a1b3195626db875563c44268 252 Gene3D G3DSA:1.10.10.60 145 251 3.2E-30 T 14-10-2018 TSH58p_12305 785c6773d70a35465559ac0bdd2e3ae9 436 Gene3D G3DSA:3.90.190.20 302 434 4.4E-15 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TSH58p_12305 785c6773d70a35465559ac0bdd2e3ae9 436 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 140 155 - T 14-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 TSH58p_12305 785c6773d70a35465559ac0bdd2e3ae9 436 SUPERFAMILY SSF53244 289 433 2.72E-17 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TSH58p_12305 785c6773d70a35465559ac0bdd2e3ae9 436 SUPERFAMILY SSF53623 11 289 3.27E-84 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TSH58p_12305 785c6773d70a35465559ac0bdd2e3ae9 436 Pfam PF08245 Mur ligase middle domain 50 263 2.5E-11 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 TSH58p_12305 785c6773d70a35465559ac0bdd2e3ae9 436 PIRSF PIRSF001563 4 435 3.4E-103 T 14-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 TSH58p_12305 785c6773d70a35465559ac0bdd2e3ae9 436 TIGRFAM TIGR01499 folC: bifunctional protein FolC 27 432 1.0E-105 T 14-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 TSH58p_12305 785c6773d70a35465559ac0bdd2e3ae9 436 Gene3D G3DSA:3.40.1190.10 3 290 1.4E-88 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TSH58p_03330 2fbf9fb5b8820a8d95d22e77d3d959f0 264 SMART SM00345 20 78 1.1E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_03330 2fbf9fb5b8820a8d95d22e77d3d959f0 264 Gene3D G3DSA:1.20.120.530 103 237 2.0E-30 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_03330 2fbf9fb5b8820a8d95d22e77d3d959f0 264 SUPERFAMILY SSF48008 100 238 1.62E-25 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_03330 2fbf9fb5b8820a8d95d22e77d3d959f0 264 SUPERFAMILY SSF46785 11 79 4.61E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_03330 2fbf9fb5b8820a8d95d22e77d3d959f0 264 Pfam PF07729 FCD domain 104 228 5.4E-25 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_03330 2fbf9fb5b8820a8d95d22e77d3d959f0 264 SMART SM00895 102 230 1.9E-19 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_03330 2fbf9fb5b8820a8d95d22e77d3d959f0 264 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 75 2.7E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_03330 2fbf9fb5b8820a8d95d22e77d3d959f0 264 Gene3D G3DSA:1.10.10.10 9 78 2.2E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_03330 2fbf9fb5b8820a8d95d22e77d3d959f0 264 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 9.2E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_03330 2fbf9fb5b8820a8d95d22e77d3d959f0 264 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 9.2E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_31025 a46d2458d2a5624c9869b4ca5478759b 399 Gene3D G3DSA:3.40.50.2300 145 363 1.8E-111 T 14-10-2018 TSH58p_31025 a46d2458d2a5624c9869b4ca5478759b 399 SUPERFAMILY SSF53822 26 397 1.38E-90 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_31025 a46d2458d2a5624c9869b4ca5478759b 399 Gene3D G3DSA:3.40.50.2300 49 355 1.8E-111 T 14-10-2018 TSH58p_31025 a46d2458d2a5624c9869b4ca5478759b 399 Pfam PF13458 Periplasmic binding protein 26 362 2.0E-89 T 14-10-2018 IPR028081 Leucine-binding protein domain TSH58p_10165 090665636c8ec7cfb89ea655ac0c8e83 339 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 339 7.9E-44 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_10165 090665636c8ec7cfb89ea655ac0c8e83 339 SUPERFAMILY SSF161098 96 324 1.11E-18 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_02635 7e4cd9812b049ab8580cba78135f3e57 104 Pfam PF03927 NapD protein 16 89 4.9E-27 T 14-10-2018 IPR005623 Chaperone NapD, nitrate reductase assembly TSH58p_02635 7e4cd9812b049ab8580cba78135f3e57 104 Gene3D G3DSA:3.30.70.920 16 84 7.1E-20 T 14-10-2018 TSH58p_02635 7e4cd9812b049ab8580cba78135f3e57 104 Hamap MF_02200 Chaperone NapD [napD]. 16 91 17.649 T 14-10-2018 IPR005623 Chaperone NapD, nitrate reductase assembly TSH58p_18475 03631c579b144f6968da6f9062dba0fb 1261 SUPERFAMILY SSF75005 1017 1218 6.41E-23 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TSH58p_18475 03631c579b144f6968da6f9062dba0fb 1261 Gene3D G3DSA:3.40.50.150 815 954 3.3E-13 T 14-10-2018 TSH58p_18475 03631c579b144f6968da6f9062dba0fb 1261 SUPERFAMILY SSF53335 815 926 2.73E-13 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_18475 03631c579b144f6968da6f9062dba0fb 1261 SUPERFAMILY SSF53335 408 581 1.2E-13 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_18475 03631c579b144f6968da6f9062dba0fb 1261 Gene3D G3DSA:3.40.50.150 442 585 4.3E-13 T 14-10-2018 TSH58p_18475 03631c579b144f6968da6f9062dba0fb 1261 Gene3D G3DSA:2.115.10.20 1014 1207 1.0E-16 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TSH58p_09875 4743ec54dffde26431c264307aac63b4 436 Pfam PF11700 Vacuole effluxer Atg22 like 146 419 1.9E-36 T 14-10-2018 IPR024671 Autophagy-related protein 22-like TSH58p_09875 4743ec54dffde26431c264307aac63b4 436 Pfam PF11700 Vacuole effluxer Atg22 like 45 139 5.3E-7 T 14-10-2018 IPR024671 Autophagy-related protein 22-like TSH58p_09875 4743ec54dffde26431c264307aac63b4 436 SUPERFAMILY SSF103473 24 422 9.55E-42 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_09875 4743ec54dffde26431c264307aac63b4 436 Gene3D G3DSA:1.20.1250.20 237 423 7.4E-17 T 14-10-2018 TSH58p_09875 4743ec54dffde26431c264307aac63b4 436 Gene3D G3DSA:1.20.1250.20 10 214 2.3E-11 T 14-10-2018 TSH58p_01675 71442e0d77b4a8671bb55d231870dea7 428 Pfam PF13546 DDE superfamily endonuclease 27 249 3.0E-56 T 14-10-2018 IPR038721 Transposase IS701-like, DDE domain TSH58p_01675 71442e0d77b4a8671bb55d231870dea7 428 SUPERFAMILY SSF53098 37 360 2.81E-22 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily TSH58p_21915 3c807f85a35b0d1adc93ddeb6bfbbdc3 451 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 163 439 7.2E-91 T 14-10-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 TSH58p_21915 3c807f85a35b0d1adc93ddeb6bfbbdc3 451 Pfam PF01458 Uncharacterized protein family (UPF0051) 199 423 1.5E-79 T 14-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 TSH58p_21915 3c807f85a35b0d1adc93ddeb6bfbbdc3 451 SUPERFAMILY SSF101960 38 445 1.96E-115 T 14-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily TSH58p_10445 e491c2fcf5da007c50c68d9566d99924 508 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 85 415 1.9E-91 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain TSH58p_10445 e491c2fcf5da007c50c68d9566d99924 508 Gene3D G3DSA:3.10.105.10 280 475 4.5E-48 T 14-10-2018 TSH58p_10445 e491c2fcf5da007c50c68d9566d99924 508 Gene3D G3DSA:3.40.190.10 23 279 6.6E-72 T 14-10-2018 TSH58p_10445 e491c2fcf5da007c50c68d9566d99924 508 PIRSF PIRSF002741 4 507 7.7E-104 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TSH58p_10445 e491c2fcf5da007c50c68d9566d99924 508 SUPERFAMILY SSF53850 42 495 4.35E-128 T 14-10-2018 TSH58p_10445 e491c2fcf5da007c50c68d9566d99924 508 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 91 113 - T 14-10-2018 IPR023765 Solute-binding protein family 5, conserved site TSH58p_12370 5d142db75776b6e4f4a03fb1896ba919 258 SMART SM00357 22 86 3.5E-6 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 TSH58p_12370 5d142db75776b6e4f4a03fb1896ba919 258 SMART SM00357 194 258 1.2E-21 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 TSH58p_12370 5d142db75776b6e4f4a03fb1896ba919 258 Gene3D G3DSA:2.40.50.140 191 256 8.2E-24 T 14-10-2018 TSH58p_12370 5d142db75776b6e4f4a03fb1896ba919 258 Gene3D G3DSA:2.40.50.140 19 84 5.8E-11 T 14-10-2018 TSH58p_12370 5d142db75776b6e4f4a03fb1896ba919 258 PRINTS PR00050 Cold shock protein signature 195 210 2.6E-13 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_12370 5d142db75776b6e4f4a03fb1896ba919 258 PRINTS PR00050 Cold shock protein signature 216 225 2.6E-13 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_12370 5d142db75776b6e4f4a03fb1896ba919 258 PRINTS PR00050 Cold shock protein signature 231 249 2.6E-13 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_12370 5d142db75776b6e4f4a03fb1896ba919 258 SUPERFAMILY SSF50249 193 255 3.21E-20 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_12370 5d142db75776b6e4f4a03fb1896ba919 258 SUPERFAMILY SSF50249 19 83 1.57E-10 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_12370 5d142db75776b6e4f4a03fb1896ba919 258 ProSitePatterns PS00352 'Cold-shock' domain signature. 206 225 - T 14-10-2018 IPR019844 Cold-shock conserved site TSH58p_12370 5d142db75776b6e4f4a03fb1896ba919 258 Pfam PF00313 'Cold-shock' DNA-binding domain 22 80 4.8E-7 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_12370 5d142db75776b6e4f4a03fb1896ba919 258 Pfam PF00313 'Cold-shock' DNA-binding domain 194 256 1.2E-22 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_14775 a67b26cdd559305304d948ab325c53a8 454 TIGRFAM TIGR01436 glu_cys_lig_pln: glutamate--cysteine ligase 11 454 6.0E-225 T 14-10-2018 IPR011556 Glutamate--cysteine ligase, plant-type GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 TSH58p_14775 a67b26cdd559305304d948ab325c53a8 454 PIRSF PIRSF017901 1 454 2.5E-193 T 14-10-2018 IPR035434 Glutamate--cysteine ligase, bacteria and plant GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 TSH58p_14775 a67b26cdd559305304d948ab325c53a8 454 Gene3D G3DSA:3.30.590.20 6 454 8.4E-189 T 14-10-2018 TSH58p_14775 a67b26cdd559305304d948ab325c53a8 454 SUPERFAMILY SSF55931 25 452 4.51E-71 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TSH58p_14775 a67b26cdd559305304d948ab325c53a8 454 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 51 358 6.9E-101 T 14-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 TSH58p_07800 d5fc64b17d692a0e74bf8d965668500c 726 Pfam PF00672 HAMP domain 381 429 2.1E-6 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_07800 d5fc64b17d692a0e74bf8d965668500c 726 Gene3D G3DSA:1.20.1480.50 344 435 1.1E-12 T 14-10-2018 TSH58p_07800 d5fc64b17d692a0e74bf8d965668500c 726 Pfam PF02743 Cache domain 48 331 3.5E-20 T 14-10-2018 IPR033479 Double Cache domain 1 TSH58p_07800 d5fc64b17d692a0e74bf8d965668500c 726 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 529 687 7.3E-29 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_07800 d5fc64b17d692a0e74bf8d965668500c 726 Gene3D G3DSA:1.10.287.950 436 720 1.3E-51 T 14-10-2018 TSH58p_07800 d5fc64b17d692a0e74bf8d965668500c 726 Gene3D G3DSA:3.30.450.20 73 237 1.5E-55 T 14-10-2018 TSH58p_07800 d5fc64b17d692a0e74bf8d965668500c 726 Gene3D G3DSA:3.30.450.20 67 340 1.5E-55 T 14-10-2018 TSH58p_07800 d5fc64b17d692a0e74bf8d965668500c 726 SMART SM00304 479 532 98.0 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_07800 d5fc64b17d692a0e74bf8d965668500c 726 SMART SM00304 380 432 1.1E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_07800 d5fc64b17d692a0e74bf8d965668500c 726 SMART SM00283 462 720 1.0E-44 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_07800 d5fc64b17d692a0e74bf8d965668500c 726 SUPERFAMILY SSF58104 400 719 4.19E-62 T 14-10-2018 TSH58p_25115 1ab0a28a1ba01459175336fdf0f70d66 437 Gene3D G3DSA:1.25.40.10 1 162 1.3E-26 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25115 1ab0a28a1ba01459175336fdf0f70d66 437 SUPERFAMILY SSF53756 177 422 2.35E-17 T 14-10-2018 TSH58p_25115 1ab0a28a1ba01459175336fdf0f70d66 437 Gene3D G3DSA:3.40.50.2000 299 418 3.2E-5 T 14-10-2018 TSH58p_25115 1ab0a28a1ba01459175336fdf0f70d66 437 SUPERFAMILY SSF48452 2 148 1.21E-23 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25115 1ab0a28a1ba01459175336fdf0f70d66 437 SMART SM00028 55 88 1.3E-5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25115 1ab0a28a1ba01459175336fdf0f70d66 437 SMART SM00028 21 54 0.0049 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25115 1ab0a28a1ba01459175336fdf0f70d66 437 Pfam PF13424 Tetratricopeptide repeat 23 84 1.8E-7 T 14-10-2018 TSH58p_07585 0a01cddbd8d5acacb94addad31526d75 69 TIGRFAM TIGR02934 nifT_nitrog: probable nitrogen fixation protein FixT 1 65 4.3E-32 T 14-10-2018 IPR009727 NifT/FixU GO:0009399 TSH58p_07585 0a01cddbd8d5acacb94addad31526d75 69 Pfam PF06988 NifT/FixU protein 1 63 1.6E-28 T 14-10-2018 IPR009727 NifT/FixU GO:0009399 TSH58p_07585 0a01cddbd8d5acacb94addad31526d75 69 SUPERFAMILY SSF159203 1 65 2.88E-25 T 14-10-2018 IPR024044 NifT/FixU barrel-like domain superfamily TSH58p_07585 0a01cddbd8d5acacb94addad31526d75 69 Gene3D G3DSA:2.40.50.240 1 66 5.2E-31 T 14-10-2018 IPR024044 NifT/FixU barrel-like domain superfamily TSH58p_15930 10695c8e526b62f547669034eb0fe1e2 387 Gene3D G3DSA:3.30.930.10 6 333 2.7E-59 T 14-10-2018 TSH58p_15930 10695c8e526b62f547669034eb0fe1e2 387 Pfam PF13393 Histidyl-tRNA synthetase 14 321 6.8E-91 T 14-10-2018 TSH58p_15930 10695c8e526b62f547669034eb0fe1e2 387 SUPERFAMILY SSF55681 11 324 2.99E-46 T 14-10-2018 TSH58p_15930 10695c8e526b62f547669034eb0fe1e2 387 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 21 368 25.21 T 14-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 TSH58p_15930 10695c8e526b62f547669034eb0fe1e2 387 PIRSF PIRSF001549 6 351 3.9E-40 T 14-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 TSH58p_25725 2c580f327669782af1fb4f3971761547 226 Gene3D G3DSA:1.10.3480.10 5 207 1.4E-34 T 14-10-2018 TSH58p_25725 2c580f327669782af1fb4f3971761547 226 Pfam PF02613 Nitrate reductase delta subunit 47 173 8.2E-28 T 14-10-2018 IPR020945 DMSO/Nitrate reductase chaperone TSH58p_25725 2c580f327669782af1fb4f3971761547 226 SUPERFAMILY SSF89155 6 206 2.35E-44 T 14-10-2018 IPR036411 TorD-like superfamily TSH58p_16105 cd9fefa839f5b19f0d652f05fa7d36cc 160 SUPERFAMILY SSF52833 1 157 4.82E-40 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_16105 cd9fefa839f5b19f0d652f05fa7d36cc 160 Gene3D G3DSA:3.40.30.10 1 160 2.3E-61 T 14-10-2018 TSH58p_16105 cd9fefa839f5b19f0d652f05fa7d36cc 160 Pfam PF08534 Redoxin 4 157 3.9E-38 T 14-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 TSH58p_09410 c7d601b56473ce138437f12a97283898 522 Pfam PF01921 tRNA synthetases class I (K) 12 365 2.3E-134 T 14-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 TSH58p_09410 c7d601b56473ce138437f12a97283898 522 SUPERFAMILY SSF52374 13 330 1.61E-58 T 14-10-2018 TSH58p_09410 c7d601b56473ce138437f12a97283898 522 SUPERFAMILY SSF48163 329 519 5.75E-40 T 14-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TSH58p_09410 c7d601b56473ce138437f12a97283898 522 Gene3D G3DSA:1.10.10.350 427 519 4.6E-18 T 14-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TSH58p_09410 c7d601b56473ce138437f12a97283898 522 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 44 53 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_09410 c7d601b56473ce138437f12a97283898 522 Gene3D G3DSA:2.30.30.300 183 228 4.3E-72 T 14-10-2018 IPR023386 Lysine-tRNA ligase, insertion domain superfamily GO:0004824 KEGG: 00970+6.1.1.6 TSH58p_09410 c7d601b56473ce138437f12a97283898 522 Gene3D G3DSA:3.40.50.620 21 281 4.3E-72 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_09410 c7d601b56473ce138437f12a97283898 522 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 12 520 30.116 T 14-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 TSH58p_04820 b7ea152463d78871ebcb062457f2be7d 294 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 246 268 4.4E-9 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSH58p_04820 b7ea152463d78871ebcb062457f2be7d 294 Gene3D G3DSA:3.40.50.300 2 274 2.4E-53 T 14-10-2018 TSH58p_04820 b7ea152463d78871ebcb062457f2be7d 294 SUPERFAMILY SSF52540 10 269 5.71E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_04820 b7ea152463d78871ebcb062457f2be7d 294 Pfam PF00005 ABC transporter 28 196 9.0E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_04820 b7ea152463d78871ebcb062457f2be7d 294 SMART SM00382 36 246 1.7E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_00940 812ee7cee88dfdea30f5b54322eb80dc 710 SUPERFAMILY SSF49785 1 77 8.5E-5 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily TSH58p_00940 812ee7cee88dfdea30f5b54322eb80dc 710 SUPERFAMILY SSF49303 630 687 2.3E-7 T 14-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily TSH58p_00940 812ee7cee88dfdea30f5b54322eb80dc 710 SUPERFAMILY SSF49303 91 178 3.84E-6 T 14-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily TSH58p_00940 812ee7cee88dfdea30f5b54322eb80dc 710 Gene3D G3DSA:3.20.20.80 170 513 2.8E-72 T 14-10-2018 TSH58p_00940 812ee7cee88dfdea30f5b54322eb80dc 710 SUPERFAMILY SSF51445 176 515 1.65E-77 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_23830 0e7e22d842b280de26dff064847ae787 170 SUPERFAMILY SSF46689 26 139 3.58E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_23830 0e7e22d842b280de26dff064847ae787 170 Pfam PF13592 Winged helix-turn helix 111 164 1.3E-17 T 14-10-2018 IPR025959 Winged helix-turn helix domain TSH58p_23830 0e7e22d842b280de26dff064847ae787 170 Pfam PF13551 Winged helix-turn helix 31 91 2.1E-12 T 14-10-2018 TSH58p_02045 1241fecf4d3164914f9ddfbff5b3ceae 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 59 1.5E-12 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSH58p_02045 1241fecf4d3164914f9ddfbff5b3ceae 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 31 42 1.5E-12 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSH58p_02045 1241fecf4d3164914f9ddfbff5b3ceae 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 12 27 1.5E-12 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSH58p_02045 1241fecf4d3164914f9ddfbff5b3ceae 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 1.5E-12 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSH58p_02045 1241fecf4d3164914f9ddfbff5b3ceae 104 Pfam PF01022 Bacterial regulatory protein, arsR family 20 62 2.7E-17 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSH58p_02045 1241fecf4d3164914f9ddfbff5b3ceae 104 SUPERFAMILY SSF46785 6 92 2.45E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_02045 1241fecf4d3164914f9ddfbff5b3ceae 104 Gene3D G3DSA:1.10.10.10 1 92 2.3E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_02045 1241fecf4d3164914f9ddfbff5b3ceae 104 SMART SM00418 10 88 1.9E-25 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSH58p_22195 2dfd7ed30e83996984471d2f9dd8169f 493 SMART SM00382 274 420 1.5E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_22195 2dfd7ed30e83996984471d2f9dd8169f 493 Gene3D G3DSA:3.40.50.300 253 418 3.4E-29 T 14-10-2018 TSH58p_22195 2dfd7ed30e83996984471d2f9dd8169f 493 SUPERFAMILY SSF52540 249 483 5.33E-22 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_22195 2dfd7ed30e83996984471d2f9dd8169f 493 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 278 415 4.8E-10 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSH58p_32065 4f625122fbd1f0ab86903b35cd78b327 420 Gene3D G3DSA:3.30.565.10 264 417 2.4E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_32065 4f625122fbd1f0ab86903b35cd78b327 420 SMART SM00065 35 177 1.7E-9 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_32065 4f625122fbd1f0ab86903b35cd78b327 420 SUPERFAMILY SSF47384 182 255 1.0E-7 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_32065 4f625122fbd1f0ab86903b35cd78b327 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 370 4.5E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_32065 4f625122fbd1f0ab86903b35cd78b327 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 393 4.5E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_32065 4f625122fbd1f0ab86903b35cd78b327 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 412 4.5E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_32065 4f625122fbd1f0ab86903b35cd78b327 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 342 356 4.5E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_32065 4f625122fbd1f0ab86903b35cd78b327 420 Pfam PF00512 His Kinase A (phospho-acceptor) domain 196 254 1.4E-6 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_32065 4f625122fbd1f0ab86903b35cd78b327 420 Gene3D G3DSA:1.10.287.130 184 262 1.4E-7 T 14-10-2018 TSH58p_32065 4f625122fbd1f0ab86903b35cd78b327 420 SUPERFAMILY SSF55781 17 185 3.27E-21 T 14-10-2018 TSH58p_32065 4f625122fbd1f0ab86903b35cd78b327 420 Gene3D G3DSA:3.30.450.40 12 183 3.7E-24 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_32065 4f625122fbd1f0ab86903b35cd78b327 420 SUPERFAMILY SSF55874 251 413 4.85E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_32065 4f625122fbd1f0ab86903b35cd78b327 420 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 312 413 7.4E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_32065 4f625122fbd1f0ab86903b35cd78b327 420 SMART SM00387 306 415 3.4E-27 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_32065 4f625122fbd1f0ab86903b35cd78b327 420 SMART SM00388 196 260 8.8E-4 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_32065 4f625122fbd1f0ab86903b35cd78b327 420 Pfam PF13185 GAF domain 35 167 1.1E-7 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_32315 77371e0e8c379769b5d3e9706c330617 115 Gene3D G3DSA:3.30.1330.40 1 115 2.2E-27 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TSH58p_32315 77371e0e8c379769b5d3e9706c330617 115 SUPERFAMILY SSF55298 11 115 4.4E-24 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TSH58p_32315 77371e0e8c379769b5d3e9706c330617 115 Pfam PF01042 Endoribonuclease L-PSP 14 114 6.6E-17 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 TSH58p_01005 e33f3735fd4d90e78e5797a8a6b37325 351 Gene3D G3DSA:3.40.190.10 164 300 1.1E-17 T 14-10-2018 TSH58p_01005 e33f3735fd4d90e78e5797a8a6b37325 351 Gene3D G3DSA:3.40.190.10 18 163 5.1E-21 T 14-10-2018 TSH58p_01005 e33f3735fd4d90e78e5797a8a6b37325 351 Pfam PF13531 Bacterial extracellular solute-binding protein 60 306 2.1E-18 T 14-10-2018 TSH58p_01005 e33f3735fd4d90e78e5797a8a6b37325 351 SUPERFAMILY SSF53850 47 317 1.37E-38 T 14-10-2018 TSH58p_18135 f7d05d53821d7d0fc45f8b87fd7ce93e 577 SMART SM00729 211 430 1.8E-20 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSH58p_18135 f7d05d53821d7d0fc45f8b87fd7ce93e 577 Gene3D G3DSA:3.80.30.20 210 420 3.4E-16 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TSH58p_18135 f7d05d53821d7d0fc45f8b87fd7ce93e 577 SUPERFAMILY SSF102114 190 418 1.7E-37 T 14-10-2018 TSH58p_18135 f7d05d53821d7d0fc45f8b87fd7ce93e 577 Pfam PF04055 Radical SAM superfamily 218 384 1.3E-10 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSH58p_31170 664677c544797d436c9538fecc3bd6e4 223 Gene3D G3DSA:3.40.50.720 9 223 7.1E-67 T 14-10-2018 TSH58p_31170 664677c544797d436c9538fecc3bd6e4 223 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 148 159 2.1E-8 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSH58p_31170 664677c544797d436c9538fecc3bd6e4 223 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 19 39 2.1E-8 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSH58p_31170 664677c544797d436c9538fecc3bd6e4 223 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 17 220 6.8E-52 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSH58p_31170 664677c544797d436c9538fecc3bd6e4 223 SMART SM00839 10 220 4.8E-63 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSH58p_31170 664677c544797d436c9538fecc3bd6e4 223 SUPERFAMILY SSF51735 18 222 1.81E-60 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_14645 267142c8d4db1d6dd313073c3d073bc8 447 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TSH58p_14645 267142c8d4db1d6dd313073c3d073bc8 447 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TSH58p_14645 267142c8d4db1d6dd313073c3d073bc8 447 SUPERFAMILY SSF52440 1 113 2.23E-49 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TSH58p_14645 267142c8d4db1d6dd313073c3d073bc8 447 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 320 1.6E-80 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TSH58p_14645 267142c8d4db1d6dd313073c3d073bc8 447 SUPERFAMILY SSF51246 330 443 3.19E-40 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TSH58p_14645 267142c8d4db1d6dd313073c3d073bc8 447 Gene3D G3DSA:3.30.470.130 1 445 6.6E-187 T 14-10-2018 TSH58p_14645 267142c8d4db1d6dd313073c3d073bc8 447 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 445 4.2E-216 T 14-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 TSH58p_14645 267142c8d4db1d6dd313073c3d073bc8 447 SMART SM00878 335 440 4.0E-59 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TSH58p_14645 267142c8d4db1d6dd313073c3d073bc8 447 SUPERFAMILY SSF56059 83 345 4.24E-71 T 14-10-2018 TSH58p_14645 267142c8d4db1d6dd313073c3d073bc8 447 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.8E-46 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TSH58p_14645 267142c8d4db1d6dd313073c3d073bc8 447 Pfam PF02785 Biotin carboxylase C-terminal domain 335 441 5.0E-37 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TSH58p_27800 77a4821be4c0ad684023783bbe93f9ea 823 Gene3D G3DSA:3.30.70.100 677 770 6.8E-21 T 14-10-2018 TSH58p_27800 77a4821be4c0ad684023783bbe93f9ea 823 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 639 673 - T 14-10-2018 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 TSH58p_27800 77a4821be4c0ad684023783bbe93f9ea 823 Pfam PF12607 Protein of unknown function (DUF3772) 87 142 1.3E-11 T 14-10-2018 IPR022249 Domain of unknown function DUF3772 TSH58p_27800 77a4821be4c0ad684023783bbe93f9ea 823 SUPERFAMILY SSF50182 609 675 5.56E-18 T 14-10-2018 IPR010920 LSM domain superfamily TSH58p_27800 77a4821be4c0ad684023783bbe93f9ea 823 SUPERFAMILY SSF82689 678 776 1.44E-25 T 14-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 TSH58p_27800 77a4821be4c0ad684023783bbe93f9ea 823 Pfam PF00924 Mechanosensitive ion channel 571 766 2.0E-53 T 14-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 TSH58p_27800 77a4821be4c0ad684023783bbe93f9ea 823 SUPERFAMILY SSF82861 525 608 1.44E-11 T 14-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 TSH58p_27800 77a4821be4c0ad684023783bbe93f9ea 823 Gene3D G3DSA:2.30.30.60 625 674 7.4E-14 T 14-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily TSH58p_19150 516e6084375dc37b67b3335bb0c255c4 333 Gene3D G3DSA:3.40.50.2000 166 333 1.0E-21 T 14-10-2018 TSH58p_19150 516e6084375dc37b67b3335bb0c255c4 333 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 137 298 4.0E-14 T 14-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 TSH58p_19150 516e6084375dc37b67b3335bb0c255c4 333 Gene3D G3DSA:3.40.50.2000 16 155 2.5E-9 T 14-10-2018 TSH58p_19150 516e6084375dc37b67b3335bb0c255c4 333 SUPERFAMILY SSF53756 20 331 1.57E-44 T 14-10-2018 TSH58p_30685 ba2d4837de772efa823124c9aa939583 335 Gene3D G3DSA:3.40.190.10 21 125 9.7E-9 T 14-10-2018 TSH58p_30685 ba2d4837de772efa823124c9aa939583 335 Pfam PF09084 NMT1/THI5 like 40 191 1.9E-7 T 14-10-2018 IPR015168 SsuA/THI5-like TSH58p_30685 ba2d4837de772efa823124c9aa939583 335 SUPERFAMILY SSF53850 28 246 1.75E-25 T 14-10-2018 TSH58p_30685 ba2d4837de772efa823124c9aa939583 335 Gene3D G3DSA:3.40.190.10 139 333 1.8E-13 T 14-10-2018 TSH58p_04905 9cee2fc6e645454dd2611ba0a3cb5e86 999 SUPERFAMILY SSF142984 758 795 6.93E-5 T 14-10-2018 TSH58p_04905 9cee2fc6e645454dd2611ba0a3cb5e86 999 Gene3D G3DSA:3.10.560.10 890 964 3.2E-10 T 14-10-2018 TSH58p_04905 9cee2fc6e645454dd2611ba0a3cb5e86 999 Pfam PF02563 Polysaccharide biosynthesis/export protein 80 152 3.3E-7 T 14-10-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 TSH58p_04905 9cee2fc6e645454dd2611ba0a3cb5e86 999 Gene3D G3DSA:3.10.560.10 666 750 1.8E-7 T 14-10-2018 TSH58p_04905 9cee2fc6e645454dd2611ba0a3cb5e86 999 Gene3D G3DSA:3.10.560.10 149 245 1.2E-12 T 14-10-2018 TSH58p_04905 9cee2fc6e645454dd2611ba0a3cb5e86 999 Pfam PF10531 SLBB domain 682 719 0.001 T 14-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_04905 9cee2fc6e645454dd2611ba0a3cb5e86 999 Pfam PF10531 SLBB domain 760 795 1.0E-9 T 14-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_04905 9cee2fc6e645454dd2611ba0a3cb5e86 999 Pfam PF10531 SLBB domain 162 209 9.0E-8 T 14-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_04905 9cee2fc6e645454dd2611ba0a3cb5e86 999 Pfam PF06251 Capsule biosynthesis GfcC 819 966 2.3E-16 T 14-10-2018 IPR010425 Domain of unknown function DUF1017 TSH58p_14170 91bf422e2efbd09568c9a222aff0e83e 149 Pfam PF03733 Inner membrane component domain 79 128 1.4E-17 T 14-10-2018 IPR005185 Inner membrane component domain TSH58p_14170 91bf422e2efbd09568c9a222aff0e83e 149 Pfam PF03733 Inner membrane component domain 7 57 1.1E-16 T 14-10-2018 IPR005185 Inner membrane component domain TSH58p_14170 91bf422e2efbd09568c9a222aff0e83e 149 PIRSF PIRSF028777 4 141 2.0E-45 T 14-10-2018 IPR031308 Uncharacterised conserved protein UCP028777 TSH58p_32160 259fb0742676e3a9ee0b1985c61ec53e 361 Pfam PF09084 NMT1/THI5 like 48 263 1.7E-12 T 14-10-2018 IPR015168 SsuA/THI5-like TSH58p_32160 259fb0742676e3a9ee0b1985c61ec53e 361 Gene3D G3DSA:3.40.190.10 121 227 6.0E-26 T 14-10-2018 TSH58p_32160 259fb0742676e3a9ee0b1985c61ec53e 361 Gene3D G3DSA:3.40.190.10 49 339 6.0E-26 T 14-10-2018 TSH58p_32160 259fb0742676e3a9ee0b1985c61ec53e 361 SUPERFAMILY SSF53850 35 271 6.37E-27 T 14-10-2018 TSH58p_18405 ac9b1eb95f88fc987b39c0fbac7ac575 345 Pfam PF00535 Glycosyl transferase family 2 58 170 1.2E-21 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_18405 ac9b1eb95f88fc987b39c0fbac7ac575 345 Gene3D G3DSA:3.90.550.10 29 267 7.6E-45 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_18405 ac9b1eb95f88fc987b39c0fbac7ac575 345 SUPERFAMILY SSF53448 56 260 2.63E-42 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_12600 a9f608a100777f72856a601c9586bc18 513 Pfam PF01593 Flavin containing amine oxidoreductase 12 285 1.3E-19 T 14-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 TSH58p_12600 a9f608a100777f72856a601c9586bc18 513 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 6 504 3.0E-123 T 14-10-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 TSH58p_12600 a9f608a100777f72856a601c9586bc18 513 Gene3D G3DSA:3.50.50.60 2 112 6.7E-20 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_12600 a9f608a100777f72856a601c9586bc18 513 Gene3D G3DSA:3.50.50.60 214 323 2.9E-21 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_12600 a9f608a100777f72856a601c9586bc18 513 SUPERFAMILY SSF51905 3 500 9.62E-64 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_09585 adaa1dabc5be4d66be51cf1aef11b5ae 103 SUPERFAMILY SSF52091 5 98 5.89E-9 T 14-10-2018 IPR036513 STAS domain superfamily TSH58p_09585 adaa1dabc5be4d66be51cf1aef11b5ae 103 Pfam PF13466 STAS domain 16 94 1.8E-9 T 14-10-2018 IPR002645 STAS domain TSH58p_09585 adaa1dabc5be4d66be51cf1aef11b5ae 103 Gene3D G3DSA:3.30.750.24 2 102 1.0E-10 T 14-10-2018 IPR036513 STAS domain superfamily TSH58p_04890 92ecf9d02eed094f1bd6731ad6bda20d 174 Pfam PF01047 MarR family 55 112 1.9E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_04890 92ecf9d02eed094f1bd6731ad6bda20d 174 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 87 1.2E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_04890 92ecf9d02eed094f1bd6731ad6bda20d 174 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 103 1.2E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_04890 92ecf9d02eed094f1bd6731ad6bda20d 174 PRINTS PR00598 Bacterial regulatory protein MarR family signature 107 123 1.2E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_04890 92ecf9d02eed094f1bd6731ad6bda20d 174 PRINTS PR00598 Bacterial regulatory protein MarR family signature 137 157 1.2E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_04890 92ecf9d02eed094f1bd6731ad6bda20d 174 Gene3D G3DSA:1.10.10.10 14 162 5.6E-37 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_04890 92ecf9d02eed094f1bd6731ad6bda20d 174 SMART SM00347 47 147 1.3E-20 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_04890 92ecf9d02eed094f1bd6731ad6bda20d 174 SUPERFAMILY SSF46785 23 162 7.16E-35 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_05100 193bb8765c8da3cb6dc97b953e2b7493 207 Gene3D G3DSA:3.20.20.70 3 204 6.1E-58 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_05100 193bb8765c8da3cb6dc97b953e2b7493 207 Pfam PF02581 Thiamine monophosphate synthase 10 186 1.2E-42 T 14-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSH58p_05100 193bb8765c8da3cb6dc97b953e2b7493 207 SUPERFAMILY SSF51391 4 194 9.42E-52 T 14-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSH58p_24150 930141716be1f39a64949023a40ad94c 468 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 411 463 1.2E-8 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain TSH58p_24150 930141716be1f39a64949023a40ad94c 468 SUPERFAMILY SSF64518 105 463 5.75E-15 T 14-10-2018 TSH58p_24150 930141716be1f39a64949023a40ad94c 468 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 7 463 4.4E-64 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 TSH58p_09595 71d0c537b49c89c6bd5badaa89dddd96 745 SMART SM00073 3 101 2.1E-26 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TSH58p_09595 71d0c537b49c89c6bd5badaa89dddd96 745 SMART SM01231 334 397 1.4E-21 T 14-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 TSH58p_09595 71d0c537b49c89c6bd5badaa89dddd96 745 SUPERFAMILY SSF47226 4 128 6.67E-28 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_09595 71d0c537b49c89c6bd5badaa89dddd96 745 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 445 582 5.0E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_09595 71d0c537b49c89c6bd5badaa89dddd96 745 Gene3D G3DSA:1.10.287.560 334 397 9.5E-17 T 14-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 TSH58p_09595 71d0c537b49c89c6bd5badaa89dddd96 745 PRINTS PR00344 Bacterial sensor protein C-terminal signature 527 537 4.8E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_09595 71d0c537b49c89c6bd5badaa89dddd96 745 PRINTS PR00344 Bacterial sensor protein C-terminal signature 487 501 4.8E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_09595 71d0c537b49c89c6bd5badaa89dddd96 745 PRINTS PR00344 Bacterial sensor protein C-terminal signature 543 561 4.8E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_09595 71d0c537b49c89c6bd5badaa89dddd96 745 PRINTS PR00344 Bacterial sensor protein C-terminal signature 567 580 4.8E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_09595 71d0c537b49c89c6bd5badaa89dddd96 745 Gene3D G3DSA:3.30.565.10 398 582 5.7E-55 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_09595 71d0c537b49c89c6bd5badaa89dddd96 745 SUPERFAMILY SSF47384 335 398 1.02E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_09595 71d0c537b49c89c6bd5badaa89dddd96 745 Gene3D G3DSA:2.40.50.180 606 671 6.1E-37 T 14-10-2018 TSH58p_09595 71d0c537b49c89c6bd5badaa89dddd96 745 SUPERFAMILY SSF50341 582 715 1.44E-29 T 14-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 TSH58p_09595 71d0c537b49c89c6bd5badaa89dddd96 745 Pfam PF01627 Hpt domain 8 100 1.1E-16 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TSH58p_09595 71d0c537b49c89c6bd5badaa89dddd96 745 SMART SM00387 442 583 5.0E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_09595 71d0c537b49c89c6bd5badaa89dddd96 745 Pfam PF01584 CheW-like domain 588 715 3.2E-25 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TSH58p_09595 71d0c537b49c89c6bd5badaa89dddd96 745 Gene3D G3DSA:1.20.120.160 1 141 1.8E-34 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_09595 71d0c537b49c89c6bd5badaa89dddd96 745 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 335 397 1.4E-16 T 14-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 TSH58p_09595 71d0c537b49c89c6bd5badaa89dddd96 745 SMART SM00260 575 716 1.1E-36 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TSH58p_09595 71d0c537b49c89c6bd5badaa89dddd96 745 Gene3D G3DSA:2.30.30.40 583 712 6.1E-37 T 14-10-2018 TSH58p_09595 71d0c537b49c89c6bd5badaa89dddd96 745 SUPERFAMILY SSF55874 395 585 2.49E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_07415 ee54d4bf6a15744afc1b9514ab032d9f 998 Gene3D G3DSA:3.30.460.100 61 301 7.3E-64 T 14-10-2018 TSH58p_07415 ee54d4bf6a15744afc1b9514ab032d9f 998 Gene3D G3DSA:3.30.460.100 580 822 5.7E-63 T 14-10-2018 TSH58p_07415 ee54d4bf6a15744afc1b9514ab032d9f 998 Gene3D G3DSA:1.20.120.330 306 463 1.9E-47 T 14-10-2018 TSH58p_07415 ee54d4bf6a15744afc1b9514ab032d9f 998 Gene3D G3DSA:1.20.120.330 823 940 1.0E-24 T 14-10-2018 TSH58p_07415 ee54d4bf6a15744afc1b9514ab032d9f 998 Pfam PF08335 GlnD PII-uridylyltransferase 841 927 3.4E-10 T 14-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 TSH58p_07415 ee54d4bf6a15744afc1b9514ab032d9f 998 Pfam PF08335 GlnD PII-uridylyltransferase 319 460 3.1E-37 T 14-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 TSH58p_07415 ee54d4bf6a15744afc1b9514ab032d9f 998 SUPERFAMILY SSF81301 543 823 1.14E-70 T 14-10-2018 TSH58p_07415 ee54d4bf6a15744afc1b9514ab032d9f 998 SUPERFAMILY SSF81593 308 460 4.79E-38 T 14-10-2018 TSH58p_07415 ee54d4bf6a15744afc1b9514ab032d9f 998 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 49 966 17.113 T 14-10-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 TSH58p_07415 ee54d4bf6a15744afc1b9514ab032d9f 998 SUPERFAMILY SSF81593 826 972 1.26E-28 T 14-10-2018 TSH58p_07415 ee54d4bf6a15744afc1b9514ab032d9f 998 SUPERFAMILY SSF81301 41 307 3.88E-66 T 14-10-2018 TSH58p_07415 ee54d4bf6a15744afc1b9514ab032d9f 998 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 572 815 9.5E-60 T 14-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 TSH58p_07415 ee54d4bf6a15744afc1b9514ab032d9f 998 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 55 298 2.5E-63 T 14-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 TSH58p_04365 925f1f5a84a07bed096f2a5c140780fc 340 Pfam PF13180 PDZ domain 247 325 1.1E-11 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_04365 925f1f5a84a07bed096f2a5c140780fc 340 Gene3D G3DSA:2.40.10.120 18 238 9.0E-20 T 14-10-2018 TSH58p_04365 925f1f5a84a07bed096f2a5c140780fc 340 Gene3D G3DSA:2.30.42.10 245 333 1.3E-13 T 14-10-2018 TSH58p_04365 925f1f5a84a07bed096f2a5c140780fc 340 PRINTS PR00834 HtrA/DegQ protease family signature 195 212 5.3E-8 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_04365 925f1f5a84a07bed096f2a5c140780fc 340 PRINTS PR00834 HtrA/DegQ protease family signature 275 287 5.3E-8 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_04365 925f1f5a84a07bed096f2a5c140780fc 340 PRINTS PR00834 HtrA/DegQ protease family signature 78 90 5.3E-8 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_04365 925f1f5a84a07bed096f2a5c140780fc 340 PRINTS PR00834 HtrA/DegQ protease family signature 99 119 5.3E-8 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSH58p_04365 925f1f5a84a07bed096f2a5c140780fc 340 SUPERFAMILY SSF50156 245 325 1.84E-13 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 TSH58p_04365 925f1f5a84a07bed096f2a5c140780fc 340 SMART SM00228 247 318 3.6E-9 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_04365 925f1f5a84a07bed096f2a5c140780fc 340 Pfam PF13365 Trypsin-like peptidase domain 69 202 3.1E-13 T 14-10-2018 TSH58p_04365 925f1f5a84a07bed096f2a5c140780fc 340 SUPERFAMILY SSF50494 39 239 9.74E-26 T 14-10-2018 IPR009003 Peptidase S1, PA clan TSH58p_18055 c71155bc9fd11b7105df775152df2c9a 441 SUPERFAMILY SSF52413 303 428 3.27E-38 T 14-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 TSH58p_18055 c71155bc9fd11b7105df775152df2c9a 441 PIRSF PIRSF500134 1 436 3.8E-187 T 14-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 TSH58p_18055 c71155bc9fd11b7105df775152df2c9a 441 PIRSF PIRSF000124 1 433 1.2E-143 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 TSH58p_18055 c71155bc9fd11b7105df775152df2c9a 441 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 318 418 3.2E-31 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSH58p_18055 c71155bc9fd11b7105df775152df2c9a 441 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 201 293 3.2E-38 T 14-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSH58p_18055 c71155bc9fd11b7105df775152df2c9a 441 SMART SM00984 317 418 1.8E-48 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSH58p_18055 c71155bc9fd11b7105df775152df2c9a 441 SUPERFAMILY SSF48179 201 298 7.48E-34 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_18055 c71155bc9fd11b7105df775152df2c9a 441 Gene3D G3DSA:3.40.50.720 232 440 6.6E-79 T 14-10-2018 TSH58p_18055 c71155bc9fd11b7105df775152df2c9a 441 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 184 3.5E-67 T 14-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSH58p_18055 c71155bc9fd11b7105df775152df2c9a 441 Gene3D G3DSA:1.20.5.100 201 231 9.3E-17 T 14-10-2018 TSH58p_18055 c71155bc9fd11b7105df775152df2c9a 441 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 414 1.5E-144 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 TSH58p_18055 c71155bc9fd11b7105df775152df2c9a 441 SUPERFAMILY SSF51735 1 188 1.64E-55 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_18055 c71155bc9fd11b7105df775152df2c9a 441 Gene3D G3DSA:3.40.50.720 1 199 1.9E-82 T 14-10-2018 TSH58p_11815 ef83cf1cabe9b6ed9c33e3c31732d1b4 629 Gene3D G3DSA:3.30.565.10 1 223 1.5E-77 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_11815 ef83cf1cabe9b6ed9c33e3c31732d1b4 629 Gene3D G3DSA:3.40.50.11260 393 479 4.6E-28 T 14-10-2018 TSH58p_11815 ef83cf1cabe9b6ed9c33e3c31732d1b4 629 Gene3D G3DSA:1.20.120.790 487 625 9.3E-39 T 14-10-2018 IPR037196 HSP90, C-terminal domain TSH58p_11815 ef83cf1cabe9b6ed9c33e3c31732d1b4 629 PIRSF PIRSF002583 1 629 1.4E-213 T 14-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 TSH58p_11815 ef83cf1cabe9b6ed9c33e3c31732d1b4 629 SUPERFAMILY SSF54211 224 478 1.82E-91 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSH58p_11815 ef83cf1cabe9b6ed9c33e3c31732d1b4 629 SUPERFAMILY SSF55874 4 212 4.98E-66 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_11815 ef83cf1cabe9b6ed9c33e3c31732d1b4 629 SUPERFAMILY SSF110942 505 625 1.19E-29 T 14-10-2018 IPR037196 HSP90, C-terminal domain TSH58p_11815 ef83cf1cabe9b6ed9c33e3c31732d1b4 629 Hamap MF_00505 Chaperone protein HtpG [htpG]. 1 625 31.238 T 14-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 TSH58p_11815 ef83cf1cabe9b6ed9c33e3c31732d1b4 629 PRINTS PR00775 90kDa heat shock protein signature 4 24 1.9E-62 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal TSH58p_11815 ef83cf1cabe9b6ed9c33e3c31732d1b4 629 PRINTS PR00775 90kDa heat shock protein signature 92 109 1.9E-62 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal TSH58p_11815 ef83cf1cabe9b6ed9c33e3c31732d1b4 629 PRINTS PR00775 90kDa heat shock protein signature 124 146 1.9E-62 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal TSH58p_11815 ef83cf1cabe9b6ed9c33e3c31732d1b4 629 PRINTS PR00775 90kDa heat shock protein signature 74 91 1.9E-62 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal TSH58p_11815 ef83cf1cabe9b6ed9c33e3c31732d1b4 629 PRINTS PR00775 90kDa heat shock protein signature 25 47 1.9E-62 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal TSH58p_11815 ef83cf1cabe9b6ed9c33e3c31732d1b4 629 PRINTS PR00775 90kDa heat shock protein signature 192 210 1.9E-62 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal TSH58p_11815 ef83cf1cabe9b6ed9c33e3c31732d1b4 629 PRINTS PR00775 90kDa heat shock protein signature 174 191 1.9E-62 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal TSH58p_11815 ef83cf1cabe9b6ed9c33e3c31732d1b4 629 Pfam PF00183 Hsp90 protein 217 628 1.3E-117 T 14-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 TSH58p_11815 ef83cf1cabe9b6ed9c33e3c31732d1b4 629 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 27 184 6.8E-11 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_11815 ef83cf1cabe9b6ed9c33e3c31732d1b4 629 SMART SM00387 26 186 1.4E-6 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_11815 ef83cf1cabe9b6ed9c33e3c31732d1b4 629 Gene3D G3DSA:3.30.230.80 224 392 4.8E-63 T 14-10-2018 TSH58p_13270 f0e8490dd1b239ca75e036c4647072ee 471 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 270 307 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSH58p_13270 f0e8490dd1b239ca75e036c4647072ee 471 Gene3D G3DSA:3.40.640.10 81 360 4.7E-170 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_13270 f0e8490dd1b239ca75e036c4647072ee 471 SUPERFAMILY SSF53383 27 462 3.61E-121 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_13270 f0e8490dd1b239ca75e036c4647072ee 471 Pfam PF00202 Aminotransferase class-III 43 461 3.0E-95 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSH58p_13270 f0e8490dd1b239ca75e036c4647072ee 471 Gene3D G3DSA:3.90.1150.10 27 463 4.7E-170 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_13270 f0e8490dd1b239ca75e036c4647072ee 471 PIRSF PIRSF000521 39 465 2.0E-30 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSH58p_23520 e0236a65564f2070b0cb8ab3340ca0ae 564 SUPERFAMILY SSF48452 12 265 1.56E-39 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_23520 e0236a65564f2070b0cb8ab3340ca0ae 564 SUPERFAMILY SSF53756 300 543 4.08E-12 T 14-10-2018 TSH58p_23520 e0236a65564f2070b0cb8ab3340ca0ae 564 SMART SM00028 147 180 1.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_23520 e0236a65564f2070b0cb8ab3340ca0ae 564 SMART SM00028 113 146 0.0024 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_23520 e0236a65564f2070b0cb8ab3340ca0ae 564 SMART SM00028 11 44 55.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_23520 e0236a65564f2070b0cb8ab3340ca0ae 564 SMART SM00028 181 214 0.2 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_23520 e0236a65564f2070b0cb8ab3340ca0ae 564 SMART SM00028 45 78 0.022 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_23520 e0236a65564f2070b0cb8ab3340ca0ae 564 SMART SM00028 79 112 74.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_23520 e0236a65564f2070b0cb8ab3340ca0ae 564 SMART SM00028 215 248 0.12 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_23520 e0236a65564f2070b0cb8ab3340ca0ae 564 Pfam PF13374 Tetratricopeptide repeat 117 140 0.01 T 14-10-2018 TSH58p_23520 e0236a65564f2070b0cb8ab3340ca0ae 564 Pfam PF13374 Tetratricopeptide repeat 150 176 0.013 T 14-10-2018 TSH58p_23520 e0236a65564f2070b0cb8ab3340ca0ae 564 Pfam PF13414 TPR repeat 198 229 3.2E-7 T 14-10-2018 TSH58p_23520 e0236a65564f2070b0cb8ab3340ca0ae 564 Gene3D G3DSA:1.25.40.10 3 152 3.4E-29 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_23520 e0236a65564f2070b0cb8ab3340ca0ae 564 Gene3D G3DSA:1.25.40.10 153 189 6.4E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_23520 e0236a65564f2070b0cb8ab3340ca0ae 564 Pfam PF13432 Tetratricopeptide repeat 51 106 1.4E-6 T 14-10-2018 TSH58p_23520 e0236a65564f2070b0cb8ab3340ca0ae 564 Gene3D G3DSA:1.25.40.10 190 272 1.9E-14 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_05745 c7c6ab1e4c7a8d9c53e83576a8493e63 282 Pfam PF01148 Cytidylyltransferase family 24 273 1.3E-57 T 14-10-2018 TSH58p_05745 c7c6ab1e4c7a8d9c53e83576a8493e63 282 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 233 259 - T 14-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 TSH58p_01105 1d622965dc68048162ee10c033ce5f1f 171 Pfam PF11684 Protein of unknown function (DUF2380) 27 163 5.1E-45 T 14-10-2018 IPR021698 Protein of unknown function DUF2380 TSH58p_29655 de3dffbf47d26a1a1a7755958b60bbff 230 Pfam PF07568 Histidine kinase 41 113 9.6E-18 T 14-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain TSH58p_29655 de3dffbf47d26a1a1a7755958b60bbff 230 Gene3D G3DSA:3.30.450.20 15 93 3.2E-8 T 14-10-2018 TSH58p_29655 de3dffbf47d26a1a1a7755958b60bbff 230 SUPERFAMILY SSF55874 133 229 1.36E-11 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_29655 de3dffbf47d26a1a1a7755958b60bbff 230 Gene3D G3DSA:3.30.565.10 98 230 1.6E-20 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_28110 8f40e6e92ef15e1c57b2a62c2a4932d0 238 Gene3D G3DSA:2.60.120.380 54 172 3.0E-8 T 14-10-2018 TSH58p_28110 8f40e6e92ef15e1c57b2a62c2a4932d0 238 SUPERFAMILY SSF89260 73 168 1.11E-5 T 14-10-2018 TSH58p_19370 3c9f132748082f100e69fddecc75ef5d 650 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 60 373 1.8E-61 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TSH58p_19370 3c9f132748082f100e69fddecc75ef5d 650 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 386 613 1.0E-58 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TSH58p_04850 2f7468ad0a3b1174d3693880ee1c24fc 561 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 70 241 5.6E-15 T 14-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like TSH58p_27335 959f89f5e48151eae642f9ff2f6744c1 150 Pfam PF04657 Putative inner membrane exporter, YdcZ 10 147 2.9E-36 T 14-10-2018 IPR006750 Putative inner membrane exporter, YdcZ TSH58p_04815 3605518eeb2383e1c1f5db9de7e10332 236 Gene3D G3DSA:3.40.50.300 1 235 1.2E-59 T 14-10-2018 TSH58p_04815 3605518eeb2383e1c1f5db9de7e10332 236 SMART SM00382 26 213 3.4E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_04815 3605518eeb2383e1c1f5db9de7e10332 236 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_04815 3605518eeb2383e1c1f5db9de7e10332 236 PIRSF PIRSF039137 1 235 8.0E-103 T 14-10-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 TSH58p_04815 3605518eeb2383e1c1f5db9de7e10332 236 SUPERFAMILY SSF52540 2 232 6.02E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_04815 3605518eeb2383e1c1f5db9de7e10332 236 Pfam PF00005 ABC transporter 17 161 6.1E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_02365 8f5c4ff08ac9ae6dca07b302ef822a45 1033 Gene3D G3DSA:1.20.1640.10 10 503 1.1E-295 T 14-10-2018 TSH58p_02365 8f5c4ff08ac9ae6dca07b302ef822a45 1033 SUPERFAMILY SSF82714 711 791 4.45E-14 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_02365 8f5c4ff08ac9ae6dca07b302ef822a45 1033 SUPERFAMILY SSF82866 290 491 3.53E-47 T 14-10-2018 TSH58p_02365 8f5c4ff08ac9ae6dca07b302ef822a45 1033 SUPERFAMILY SSF82693 556 653 9.94E-12 T 14-10-2018 TSH58p_02365 8f5c4ff08ac9ae6dca07b302ef822a45 1033 SUPERFAMILY SSF82866 792 1015 2.22E-44 T 14-10-2018 TSH58p_02365 8f5c4ff08ac9ae6dca07b302ef822a45 1033 Gene3D G3DSA:3.30.70.1430 558 653 1.1E-295 T 14-10-2018 TSH58p_02365 8f5c4ff08ac9ae6dca07b302ef822a45 1033 Gene3D G3DSA:3.30.70.1320 133 326 1.1E-295 T 14-10-2018 TSH58p_02365 8f5c4ff08ac9ae6dca07b302ef822a45 1033 SUPERFAMILY SSF82693 136 324 1.92E-22 T 14-10-2018 TSH58p_02365 8f5c4ff08ac9ae6dca07b302ef822a45 1033 Gene3D G3DSA:3.30.2090.10 706 794 1.1E-295 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_02365 8f5c4ff08ac9ae6dca07b302ef822a45 1033 Gene3D G3DSA:3.30.70.1430 40 802 1.1E-295 T 14-10-2018 TSH58p_02365 8f5c4ff08ac9ae6dca07b302ef822a45 1033 Gene3D G3DSA:3.30.70.1440 654 852 1.1E-295 T 14-10-2018 TSH58p_02365 8f5c4ff08ac9ae6dca07b302ef822a45 1033 Gene3D G3DSA:1.20.1640.10 504 1010 1.1E-295 T 14-10-2018 TSH58p_02365 8f5c4ff08ac9ae6dca07b302ef822a45 1033 Gene3D G3DSA:3.30.2090.10 179 269 1.1E-295 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_02365 8f5c4ff08ac9ae6dca07b302ef822a45 1033 SUPERFAMILY SSF82714 183 265 2.35E-18 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSH58p_02365 8f5c4ff08ac9ae6dca07b302ef822a45 1033 SUPERFAMILY SSF82693 40 130 1.46E-22 T 14-10-2018 TSH58p_02365 8f5c4ff08ac9ae6dca07b302ef822a45 1033 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 6.2E-77 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_02365 8f5c4ff08ac9ae6dca07b302ef822a45 1033 PRINTS PR00702 Acriflavin resistance protein family signature 543 560 6.2E-77 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_02365 8f5c4ff08ac9ae6dca07b302ef822a45 1033 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 6.2E-77 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_02365 8f5c4ff08ac9ae6dca07b302ef822a45 1033 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 6.2E-77 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_02365 8f5c4ff08ac9ae6dca07b302ef822a45 1033 PRINTS PR00702 Acriflavin resistance protein family signature 610 624 6.2E-77 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_02365 8f5c4ff08ac9ae6dca07b302ef822a45 1033 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 6.2E-77 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_02365 8f5c4ff08ac9ae6dca07b302ef822a45 1033 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 6.2E-77 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_02365 8f5c4ff08ac9ae6dca07b302ef822a45 1033 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 6.2E-77 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_02365 8f5c4ff08ac9ae6dca07b302ef822a45 1033 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 6.2E-77 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_02365 8f5c4ff08ac9ae6dca07b302ef822a45 1033 Pfam PF00873 AcrB/AcrD/AcrF family 5 1013 0.0 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSH58p_11660 445b43d1c9a3843c04646389db121537 228 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 190 205 6.4E-11 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_11660 445b43d1c9a3843c04646389db121537 228 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 174 190 6.4E-11 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_11660 445b43d1c9a3843c04646389db121537 228 Gene3D G3DSA:1.10.10.10 146 227 1.2E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_11660 445b43d1c9a3843c04646389db121537 228 Pfam PF13545 Crp-like helix-turn-helix domain 149 221 3.6E-18 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_11660 445b43d1c9a3843c04646389db121537 228 ProSitePatterns PS00042 Crp-type HTH domain signature. 176 199 - T 14-10-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 TSH58p_11660 445b43d1c9a3843c04646389db121537 228 SUPERFAMILY SSF51206 7 144 1.2E-34 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like TSH58p_11660 445b43d1c9a3843c04646389db121537 228 SMART SM00100 14 132 2.2E-26 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_11660 445b43d1c9a3843c04646389db121537 228 SMART SM00419 168 217 3.0E-12 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_11660 445b43d1c9a3843c04646389db121537 228 SUPERFAMILY SSF46785 146 225 2.68E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_11660 445b43d1c9a3843c04646389db121537 228 Gene3D G3DSA:2.60.120.10 28 145 5.6E-44 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_11660 445b43d1c9a3843c04646389db121537 228 Pfam PF00027 Cyclic nucleotide-binding domain 34 116 1.7E-17 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_16790 a9373f8ba30bb1afe27cb58288e0d755 170 Pfam PF00805 Pentapeptide repeats (8 copies) 41 75 4.3E-5 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_16790 a9373f8ba30bb1afe27cb58288e0d755 170 Pfam PF00805 Pentapeptide repeats (8 copies) 112 151 4.4E-12 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_16790 a9373f8ba30bb1afe27cb58288e0d755 170 SUPERFAMILY SSF141571 37 155 1.57E-33 T 14-10-2018 TSH58p_16790 a9373f8ba30bb1afe27cb58288e0d755 170 Gene3D G3DSA:2.160.20.100 27 166 3.3E-34 T 14-10-2018 TSH58p_20225 fba8fc3a6fb19a38d2e9ecd58d4ab2f8 243 Pfam PF02108 Flagellar assembly protein FliH 92 203 4.6E-7 T 14-10-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE TSH58p_11245 c3c84b8881b2cd8d1f6b41b0dbadfe0b 172 PIRSF PIRSF032162 2 167 6.1E-52 T 14-10-2018 IPR016990 Uncharacterised conserved protein UCP032162, transmembrane TSH58p_11245 c3c84b8881b2cd8d1f6b41b0dbadfe0b 172 Pfam PF10003 Integral membrane protein (DUF2244) 20 158 3.3E-53 T 14-10-2018 IPR019253 Protein of unknown function DUF2244, transmembrane TSH58p_22930 92723dbaaa28649bbb56b615dd7dfce9 248 Gene3D G3DSA:3.40.50.300 1 235 5.7E-62 T 14-10-2018 TSH58p_22930 92723dbaaa28649bbb56b615dd7dfce9 248 SUPERFAMILY SSF52540 2 233 1.3E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_22930 92723dbaaa28649bbb56b615dd7dfce9 248 SMART SM00382 26 210 2.6E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_22930 92723dbaaa28649bbb56b615dd7dfce9 248 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 211 233 9.1E-11 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSH58p_22930 92723dbaaa28649bbb56b615dd7dfce9 248 Pfam PF00005 ABC transporter 18 161 2.7E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_06350 5e0dbddc7ceb7e10dfe653d0a359c356 772 SUPERFAMILY SSF56003 132 765 1.07E-191 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 TSH58p_06350 5e0dbddc7ceb7e10dfe653d0a359c356 772 Gene3D G3DSA:3.30.365.10 141 371 6.9E-112 T 14-10-2018 TSH58p_06350 5e0dbddc7ceb7e10dfe653d0a359c356 772 Gene3D G3DSA:3.30.365.10 466 615 7.0E-121 T 14-10-2018 TSH58p_06350 5e0dbddc7ceb7e10dfe653d0a359c356 772 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 158 701 3.6E-165 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 TSH58p_06350 5e0dbddc7ceb7e10dfe653d0a359c356 772 SUPERFAMILY SSF54665 4 162 5.76E-46 T 14-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily TSH58p_06350 5e0dbddc7ceb7e10dfe653d0a359c356 772 SMART SM01008 20 140 1.1E-50 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead TSH58p_06350 5e0dbddc7ceb7e10dfe653d0a359c356 772 Gene3D G3DSA:3.90.1170.50 35 140 6.9E-112 T 14-10-2018 TSH58p_06350 5e0dbddc7ceb7e10dfe653d0a359c356 772 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 20 140 1.8E-28 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead TSH58p_06350 5e0dbddc7ceb7e10dfe653d0a359c356 772 Gene3D G3DSA:3.30.365.10 19 293 6.9E-112 T 14-10-2018 TSH58p_06350 5e0dbddc7ceb7e10dfe653d0a359c356 772 Gene3D G3DSA:3.30.365.10 379 741 7.0E-121 T 14-10-2018 TSH58p_23600 22075584e0b840bbc530844007d8520c 416 Gene3D G3DSA:3.30.1540.10 229 326 4.9E-118 T 14-10-2018 TSH58p_23600 22075584e0b840bbc530844007d8520c 416 Gene3D G3DSA:3.40.50.10540 11 391 4.9E-118 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily TSH58p_23600 22075584e0b840bbc530844007d8520c 416 SUPERFAMILY SSF89796 8 397 9.68E-127 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily TSH58p_23600 22075584e0b840bbc530844007d8520c 416 Pfam PF02515 CoA-transferase family III 12 374 1.6E-118 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 TSH58p_08710 53d73d01db5d8a4ae062059cfa6c99ad 254 ProSitePatterns PS01057 SAICAR synthetase signature 1. 86 100 - T 14-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSH58p_08710 53d73d01db5d8a4ae062059cfa6c99ad 254 ProSitePatterns PS01058 SAICAR synthetase signature 2. 173 181 - T 14-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSH58p_08710 53d73d01db5d8a4ae062059cfa6c99ad 254 Pfam PF01259 SAICAR synthetase 7 235 1.4E-59 T 14-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSH58p_08710 53d73d01db5d8a4ae062059cfa6c99ad 254 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 4 238 31.44 T 14-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSH58p_08710 53d73d01db5d8a4ae062059cfa6c99ad 254 Gene3D G3DSA:3.30.200.20 7 235 2.8E-94 T 14-10-2018 TSH58p_08710 53d73d01db5d8a4ae062059cfa6c99ad 254 Gene3D G3DSA:3.30.470.20 85 224 2.8E-94 T 14-10-2018 TSH58p_08710 53d73d01db5d8a4ae062059cfa6c99ad 254 SUPERFAMILY SSF56104 4 236 1.01E-76 T 14-10-2018 TSH58p_08710 53d73d01db5d8a4ae062059cfa6c99ad 254 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 4 237 1.0E-62 T 14-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 TSH58p_16350 4d1d8f2b95c038c3ab13a3e81e79c84e 381 Gene3D G3DSA:3.40.50.2000 174 350 2.6E-49 T 14-10-2018 TSH58p_16350 4d1d8f2b95c038c3ab13a3e81e79c84e 381 Pfam PF13692 Glycosyl transferases group 1 190 331 8.1E-26 T 14-10-2018 TSH58p_16350 4d1d8f2b95c038c3ab13a3e81e79c84e 381 Gene3D G3DSA:3.40.50.2000 10 363 2.6E-49 T 14-10-2018 TSH58p_16350 4d1d8f2b95c038c3ab13a3e81e79c84e 381 Pfam PF13477 Glycosyl transferase 4-like 4 141 9.3E-19 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TSH58p_16350 4d1d8f2b95c038c3ab13a3e81e79c84e 381 SUPERFAMILY SSF53756 10 366 4.71E-59 T 14-10-2018 TSH58p_04020 bc6da51a869e3cf095ad3f272cb837ec 510 Pfam PF00772 DnaB-like helicase N terminal domain 33 134 3.2E-29 T 14-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 TSH58p_04020 bc6da51a869e3cf095ad3f272cb837ec 510 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 33 501 1.4E-157 T 14-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 TSH58p_04020 bc6da51a869e3cf095ad3f272cb837ec 510 SUPERFAMILY SSF48024 31 143 6.41E-34 T 14-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 TSH58p_04020 bc6da51a869e3cf095ad3f272cb837ec 510 Gene3D G3DSA:3.40.50.300 190 501 1.7E-102 T 14-10-2018 TSH58p_04020 bc6da51a869e3cf095ad3f272cb837ec 510 Gene3D G3DSA:1.10.860.10 26 189 6.0E-46 T 14-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal TSH58p_04020 bc6da51a869e3cf095ad3f272cb837ec 510 SUPERFAMILY SSF52540 209 492 4.34E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_04020 bc6da51a869e3cf095ad3f272cb837ec 510 Pfam PF03796 DnaB-like helicase C terminal domain 211 498 5.5E-104 T 14-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 TSH58p_06270 15d5a0927a0a8b366272bcc344effa78 402 Pfam PF05940 NnrS protein 17 396 4.6E-109 T 14-10-2018 IPR010266 NnrS TSH58p_09740 29c20b31f23013da223c9cef1e6b243a 445 Gene3D G3DSA:3.40.190.10 34 390 1.8E-130 T 14-10-2018 TSH58p_09740 29c20b31f23013da223c9cef1e6b243a 445 SUPERFAMILY SSF53850 32 432 1.14E-73 T 14-10-2018 TSH58p_09740 29c20b31f23013da223c9cef1e6b243a 445 Gene3D G3DSA:3.40.190.10 150 431 1.8E-130 T 14-10-2018 TSH58p_09740 29c20b31f23013da223c9cef1e6b243a 445 Pfam PF13416 Bacterial extracellular solute-binding protein 49 358 1.5E-35 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSH58p_21260 9511e4d5464917f9eeb0344b75447937 331 Pfam PF04055 Radical SAM superfamily 64 217 3.9E-15 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSH58p_21260 9511e4d5464917f9eeb0344b75447937 331 Hamap MF_01694 Biotin synthase [bioB]. 19 327 42.33 T 14-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 TSH58p_21260 9511e4d5464917f9eeb0344b75447937 331 SUPERFAMILY SSF102114 20 325 3.53E-90 T 14-10-2018 TSH58p_21260 9511e4d5464917f9eeb0344b75447937 331 Gene3D G3DSA:3.20.20.70 18 327 3.4E-125 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_21260 9511e4d5464917f9eeb0344b75447937 331 PIRSF PIRSF001619 4 330 9.2E-129 T 14-10-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 TSH58p_21260 9511e4d5464917f9eeb0344b75447937 331 SMART SM00729 57 269 6.2E-35 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSH58p_21260 9511e4d5464917f9eeb0344b75447937 331 TIGRFAM TIGR00433 bioB: biotin synthase 28 325 2.9E-119 T 14-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 TSH58p_21260 9511e4d5464917f9eeb0344b75447937 331 SMART SM00876 234 326 5.5E-43 T 14-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 TSH58p_21260 9511e4d5464917f9eeb0344b75447937 331 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 234 325 1.3E-16 T 14-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 TSH58p_11905 09c4982b862db399eeb644b317c0e971 123 Pfam PF00453 Ribosomal protein L20 3 109 2.9E-49 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_11905 09c4982b862db399eeb644b317c0e971 123 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_11905 09c4982b862db399eeb644b317c0e971 123 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 20 72 3.0E-19 T 14-10-2018 TSH58p_11905 09c4982b862db399eeb644b317c0e971 123 Gene3D G3DSA:1.10.1900.20 56 119 2.8E-29 T 14-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_11905 09c4982b862db399eeb644b317c0e971 123 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 29.761 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_11905 09c4982b862db399eeb644b317c0e971 123 SUPERFAMILY SSF74731 3 117 1.7E-49 T 14-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_11905 09c4982b862db399eeb644b317c0e971 123 PRINTS PR00062 Ribosomal protein L20 signature 75 101 2.5E-38 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_11905 09c4982b862db399eeb644b317c0e971 123 PRINTS PR00062 Ribosomal protein L20 signature 42 71 2.5E-38 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_11905 09c4982b862db399eeb644b317c0e971 123 PRINTS PR00062 Ribosomal protein L20 signature 12 41 2.5E-38 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_11905 09c4982b862db399eeb644b317c0e971 123 Gene3D G3DSA:1.10.720.90 2 55 2.4E-24 T 14-10-2018 TSH58p_11905 09c4982b862db399eeb644b317c0e971 123 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 113 3.2E-49 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_18285 59b6922fb8e6167ea68c23e23c3588b3 271 PIRSF PIRSF006648 4 266 1.0E-17 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSH58p_18285 59b6922fb8e6167ea68c23e23c3588b3 271 Pfam PF01061 ABC-2 type transporter 20 232 7.8E-26 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TSH58p_29650 a9125f7994b63e14b3618bc416c24b74 134 SUPERFAMILY SSF53146 1 112 1.1E-16 T 14-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TSH58p_29650 a9125f7994b63e14b3618bc416c24b74 134 Gene3D G3DSA:3.30.420.130 1 119 5.8E-12 T 14-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TSH58p_29650 a9125f7994b63e14b3618bc416c24b74 134 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 97 1.6E-6 T 14-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TSH58p_31655 65b7207991cfe82e37dcfeb02bc6e6e8 280 SUPERFAMILY SSF52540 26 256 6.25E-71 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_31655 65b7207991cfe82e37dcfeb02bc6e6e8 280 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_31655 65b7207991cfe82e37dcfeb02bc6e6e8 280 Pfam PF00005 ABC transporter 47 186 3.0E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_31655 65b7207991cfe82e37dcfeb02bc6e6e8 280 SMART SM00382 56 237 2.8E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_31655 65b7207991cfe82e37dcfeb02bc6e6e8 280 Gene3D G3DSA:3.40.50.300 24 257 2.1E-62 T 14-10-2018 TSH58p_32370 7b6d400c32c0f89bbdd5a7fa4c8f05ab 301 SUPERFAMILY SSF53850 91 295 3.26E-38 T 14-10-2018 TSH58p_32370 7b6d400c32c0f89bbdd5a7fa4c8f05ab 301 Gene3D G3DSA:1.10.10.10 1 93 1.0E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_32370 7b6d400c32c0f89bbdd5a7fa4c8f05ab 301 Gene3D G3DSA:3.40.190.290 94 296 2.0E-38 T 14-10-2018 TSH58p_32370 7b6d400c32c0f89bbdd5a7fa4c8f05ab 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.6E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_32370 7b6d400c32c0f89bbdd5a7fa4c8f05ab 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.6E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_32370 7b6d400c32c0f89bbdd5a7fa4c8f05ab 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.6E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_32370 7b6d400c32c0f89bbdd5a7fa4c8f05ab 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.1E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_32370 7b6d400c32c0f89bbdd5a7fa4c8f05ab 301 SUPERFAMILY SSF46785 1 112 1.19E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_32370 7b6d400c32c0f89bbdd5a7fa4c8f05ab 301 Pfam PF03466 LysR substrate binding domain 88 292 1.9E-38 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_26235 028ebc60907067a76940c13c10e4c518 642 Gene3D G3DSA:2.40.170.20 174 640 3.1E-105 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily TSH58p_26235 028ebc60907067a76940c13c10e4c518 642 Gene3D G3DSA:2.170.130.10 34 173 1.2E-36 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily TSH58p_26235 028ebc60907067a76940c13c10e4c518 642 Pfam PF00593 TonB dependent receptor 198 639 1.3E-48 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel TSH58p_26235 028ebc60907067a76940c13c10e4c518 642 Pfam PF07715 TonB-dependent Receptor Plug Domain 57 163 3.1E-28 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain TSH58p_26235 028ebc60907067a76940c13c10e4c518 642 SUPERFAMILY SSF56935 45 639 2.14E-116 T 14-10-2018 TSH58p_21715 01ac5e3d887797c462d59fd44085fc3f 360 Gene3D G3DSA:1.10.530.10 54 189 4.6E-31 T 14-10-2018 TSH58p_21715 01ac5e3d887797c462d59fd44085fc3f 360 SUPERFAMILY SSF53955 52 184 3.38E-32 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily TSH58p_21715 01ac5e3d887797c462d59fd44085fc3f 360 Pfam PF01464 Transglycosylase SLT domain 60 165 4.2E-16 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 TSH58p_31625 d6edb5881842aa30dffaf6b745e151bf 369 Pfam PF01032 FecCD transport family 36 361 5.5E-80 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TSH58p_31625 d6edb5881842aa30dffaf6b745e151bf 369 SUPERFAMILY SSF81345 22 362 4.18E-71 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_31625 d6edb5881842aa30dffaf6b745e151bf 369 Gene3D G3DSA:1.10.3470.10 23 368 4.8E-91 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_32365 4b040143d7e195a525d619091216b969 344 SUPERFAMILY SSF53850 23 341 1.56E-65 T 14-10-2018 TSH58p_32365 4b040143d7e195a525d619091216b969 344 Gene3D G3DSA:3.40.190.10 127 338 7.7E-84 T 14-10-2018 TSH58p_32365 4b040143d7e195a525d619091216b969 344 Pfam PF13416 Bacterial extracellular solute-binding protein 43 304 1.0E-35 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSH58p_32365 4b040143d7e195a525d619091216b969 344 Gene3D G3DSA:3.40.190.10 39 309 7.7E-84 T 14-10-2018 TSH58p_11225 4653ef0b4017f744af4ed45e99621ec1 253 SMART SM00382 30 198 3.2E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_11225 4653ef0b4017f744af4ed45e99621ec1 253 Gene3D G3DSA:3.40.50.300 4 224 7.0E-59 T 14-10-2018 TSH58p_11225 4653ef0b4017f744af4ed45e99621ec1 253 Pfam PF00005 ABC transporter 21 148 5.5E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_11225 4653ef0b4017f744af4ed45e99621ec1 253 ProSitePatterns PS00211 ABC transporters family signature. 122 136 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_11225 4653ef0b4017f744af4ed45e99621ec1 253 SUPERFAMILY SSF52540 3 216 1.31E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_00540 2b61b49a84d7c718d8c3cfcf7cbf55ca 707 SMART SM00028 181 214 10.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_00540 2b61b49a84d7c718d8c3cfcf7cbf55ca 707 SMART SM00028 215 248 41.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_00540 2b61b49a84d7c718d8c3cfcf7cbf55ca 707 SMART SM00028 249 282 43.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_00540 2b61b49a84d7c718d8c3cfcf7cbf55ca 707 SMART SM00028 75 108 1.3E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_00540 2b61b49a84d7c718d8c3cfcf7cbf55ca 707 SMART SM00028 7 40 26.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_00540 2b61b49a84d7c718d8c3cfcf7cbf55ca 707 SMART SM00028 109 141 330.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_00540 2b61b49a84d7c718d8c3cfcf7cbf55ca 707 SMART SM00028 41 74 240.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_00540 2b61b49a84d7c718d8c3cfcf7cbf55ca 707 Gene3D G3DSA:1.25.40.10 158 196 2.5E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_00540 2b61b49a84d7c718d8c3cfcf7cbf55ca 707 Gene3D G3DSA:1.25.40.10 197 305 8.0E-13 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_00540 2b61b49a84d7c718d8c3cfcf7cbf55ca 707 Pfam PF07719 Tetratricopeptide repeat 75 107 4.4E-5 T 14-10-2018 IPR013105 Tetratricopeptide repeat 2 TSH58p_00540 2b61b49a84d7c718d8c3cfcf7cbf55ca 707 Pfam PF13432 Tetratricopeptide repeat 185 249 9.9E-7 T 14-10-2018 TSH58p_00540 2b61b49a84d7c718d8c3cfcf7cbf55ca 707 Pfam PF13432 Tetratricopeptide repeat 19 69 3.3E-6 T 14-10-2018 TSH58p_00540 2b61b49a84d7c718d8c3cfcf7cbf55ca 707 SUPERFAMILY SSF48452 46 290 2.09E-20 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_00540 2b61b49a84d7c718d8c3cfcf7cbf55ca 707 Gene3D G3DSA:1.25.40.10 3 157 3.1E-24 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_08985 d17d3ca707366a64664f101330acefb1 184 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 1.6E-17 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSH58p_08985 d17d3ca707366a64664f101330acefb1 184 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 1.6E-17 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSH58p_08985 d17d3ca707366a64664f101330acefb1 184 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 1.6E-17 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSH58p_08985 d17d3ca707366a64664f101330acefb1 184 SMART SM00344 6 115 3.6E-44 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TSH58p_08985 d17d3ca707366a64664f101330acefb1 184 SUPERFAMILY SSF46785 5 66 3.63E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_08985 d17d3ca707366a64664f101330acefb1 184 Gene3D G3DSA:1.10.10.10 1 59 1.1E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_08985 d17d3ca707366a64664f101330acefb1 184 Pfam PF01037 Lrp/AsnC ligand binding domain 74 145 2.7E-18 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TSH58p_08985 d17d3ca707366a64664f101330acefb1 184 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 53 1.8E-18 T 14-10-2018 TSH58p_08985 d17d3ca707366a64664f101330acefb1 184 Gene3D G3DSA:3.30.70.920 60 143 1.5E-23 T 14-10-2018 TSH58p_08985 d17d3ca707366a64664f101330acefb1 184 SUPERFAMILY SSF54909 66 155 1.18E-18 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel TSH58p_12320 34110ed07f44a50e7dbf3283493aaed6 242 Gene3D G3DSA:3.40.50.720 8 241 4.8E-45 T 14-10-2018 TSH58p_12320 34110ed07f44a50e7dbf3283493aaed6 242 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_12320 34110ed07f44a50e7dbf3283493aaed6 242 SUPERFAMILY SSF51735 8 240 5.52E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_12320 34110ed07f44a50e7dbf3283493aaed6 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 7.8E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_12320 34110ed07f44a50e7dbf3283493aaed6 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 7.8E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_12320 34110ed07f44a50e7dbf3283493aaed6 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 7.8E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_12320 34110ed07f44a50e7dbf3283493aaed6 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 7.8E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_12320 34110ed07f44a50e7dbf3283493aaed6 242 Pfam PF00106 short chain dehydrogenase 9 186 4.2E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_08865 c7247c8af3ff81b467a5f84a964982c3 545 Gene3D G3DSA:3.40.50.970 1 182 2.7E-67 T 14-10-2018 TSH58p_08865 c7247c8af3ff81b467a5f84a964982c3 545 SUPERFAMILY SSF52467 162 335 1.46E-29 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TSH58p_08865 c7247c8af3ff81b467a5f84a964982c3 545 Gene3D G3DSA:3.40.50.1220 183 343 1.1E-58 T 14-10-2018 TSH58p_08865 c7247c8af3ff81b467a5f84a964982c3 545 Gene3D G3DSA:3.40.50.970 344 545 4.1E-62 T 14-10-2018 TSH58p_08865 c7247c8af3ff81b467a5f84a964982c3 545 PIRSF PIRSF036565 1 545 5.3E-148 T 14-10-2018 IPR012110 Thiamine pyrophosphate (TPP)-dependent enzyme GO:0016831 TSH58p_08865 c7247c8af3ff81b467a5f84a964982c3 545 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 394 517 2.0E-24 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TSH58p_08865 c7247c8af3ff81b467a5f84a964982c3 545 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 193 328 1.4E-19 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 TSH58p_08865 c7247c8af3ff81b467a5f84a964982c3 545 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 173 3.1E-37 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 TSH58p_08865 c7247c8af3ff81b467a5f84a964982c3 545 SUPERFAMILY SSF52518 353 529 1.01E-39 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_08865 c7247c8af3ff81b467a5f84a964982c3 545 TIGRFAM TIGR03394 indol_phenyl_DC: indolepyruvate/phenylpyruvate decarboxylase 2 535 0.0 T 14-10-2018 IPR017765 Indole-3-pyruvate decarboxylase GO:0009851|GO:0047434 KEGG: 00380+4.1.1.74|MetaCyc: PWY-5081 TSH58p_08865 c7247c8af3ff81b467a5f84a964982c3 545 SUPERFAMILY SSF52518 1 182 2.16E-35 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_30890 befd6506094efd4a48ed2978ff359ef8 260 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 247 3.8E-26 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_30890 befd6506094efd4a48ed2978ff359ef8 260 Gene3D G3DSA:1.10.3720.10 58 250 5.5E-25 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_30890 befd6506094efd4a48ed2978ff359ef8 260 SUPERFAMILY SSF161098 57 243 1.57E-33 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_22400 a378354aec4367578f774928c3f78b79 440 Gene3D G3DSA:3.50.50.60 197 372 4.3E-7 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_22400 a378354aec4367578f774928c3f78b79 440 Gene3D G3DSA:3.50.50.60 2 86 1.8E-11 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_22400 a378354aec4367578f774928c3f78b79 440 Pfam PF01593 Flavin containing amine oxidoreductase 11 416 5.2E-29 T 14-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 TSH58p_22400 a378354aec4367578f774928c3f78b79 440 TIGRFAM TIGR03467 HpnE: squalene-associated FAD-dependent desaturase 4 416 3.3E-113 T 14-10-2018 IPR017830 Hydroxysqualene dehydroxylase HpnE MetaCyc: PWY-7072 TSH58p_22400 a378354aec4367578f774928c3f78b79 440 SUPERFAMILY SSF51905 3 417 7.12E-41 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_22400 a378354aec4367578f774928c3f78b79 440 Gene3D G3DSA:3.30.9.10 264 370 4.3E-7 T 14-10-2018 TSH58p_26520 0628708e9ce7c58517a540cbe9678b5e 162 SUPERFAMILY SSF55804 1 146 6.93E-31 T 14-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 TSH58p_26520 0628708e9ce7c58517a540cbe9678b5e 162 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 147 2.6E-29 T 14-10-2018 IPR002178 PTS EIIA type-2 domain TSH58p_26520 0628708e9ce7c58517a540cbe9678b5e 162 Gene3D G3DSA:3.40.930.10 1 150 1.8E-39 T 14-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 TSH58p_23570 defb063bbda970907072f1b0ee8ea7ea 482 Pfam PF06114 IrrE N-terminal-like domain 194 313 1.0E-18 T 14-10-2018 IPR010359 IrrE N-terminal-like domain TSH58p_23570 defb063bbda970907072f1b0ee8ea7ea 482 Pfam PF09856 Predicted transcriptional regulator (DUF2083) 314 470 3.6E-72 T 14-10-2018 IPR018653 Domain of unknown function DUF2083,transcriptional regulator TSH58p_23570 defb063bbda970907072f1b0ee8ea7ea 482 SMART SM00530 9 64 8.6E-16 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_23570 defb063bbda970907072f1b0ee8ea7ea 482 SUPERFAMILY SSF47413 3 69 7.24E-17 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_23570 defb063bbda970907072f1b0ee8ea7ea 482 PIRSF PIRSF019251 1 475 9.4E-201 T 14-10-2018 IPR026281 HTH-type transcriptional regulator RamB GO:0006355 TSH58p_23570 defb063bbda970907072f1b0ee8ea7ea 482 Pfam PF01381 Helix-turn-helix 10 62 3.0E-15 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_23570 defb063bbda970907072f1b0ee8ea7ea 482 Gene3D G3DSA:1.10.260.40 3 72 7.8E-17 T 14-10-2018 TSH58p_00865 3028c2fdf7a849d743597c2e5c40c8ec 287 Pfam PF03641 Possible lysine decarboxylase 131 260 8.8E-30 T 14-10-2018 IPR031100 LOG family TSH58p_00865 3028c2fdf7a849d743597c2e5c40c8ec 287 Gene3D G3DSA:3.40.50.450 28 264 2.7E-57 T 14-10-2018 TSH58p_00865 3028c2fdf7a849d743597c2e5c40c8ec 287 SUPERFAMILY SSF102405 20 261 1.16E-48 T 14-10-2018 TSH58p_31250 9a064c352e60abe4f5e41e0d27a59625 296 Gene3D G3DSA:3.40.50.12370 21 295 2.1E-33 T 14-10-2018 TSH58p_31250 9a064c352e60abe4f5e41e0d27a59625 296 PRINTS PR01438 Universal stress protein signature 171 189 1.0E-7 T 14-10-2018 IPR006015 Universal stress protein A TSH58p_31250 9a064c352e60abe4f5e41e0d27a59625 296 PRINTS PR01438 Universal stress protein signature 256 268 1.0E-7 T 14-10-2018 IPR006015 Universal stress protein A TSH58p_31250 9a064c352e60abe4f5e41e0d27a59625 296 PRINTS PR01438 Universal stress protein signature 274 296 1.0E-7 T 14-10-2018 IPR006015 Universal stress protein A TSH58p_31250 9a064c352e60abe4f5e41e0d27a59625 296 Pfam PF00582 Universal stress protein family 172 294 5.8E-8 T 14-10-2018 IPR006016 UspA TSH58p_31250 9a064c352e60abe4f5e41e0d27a59625 296 Pfam PF00582 Universal stress protein family 19 162 2.5E-5 T 14-10-2018 IPR006016 UspA TSH58p_31250 9a064c352e60abe4f5e41e0d27a59625 296 SUPERFAMILY SSF52402 172 295 3.18E-19 T 14-10-2018 TSH58p_31250 9a064c352e60abe4f5e41e0d27a59625 296 SUPERFAMILY SSF52402 17 162 2.51E-10 T 14-10-2018 TSH58p_11465 b90cf9ca95de57db7743b055dfc455ed 139 Gene3D G3DSA:1.20.1260.10 1 138 6.2E-55 T 14-10-2018 IPR012347 Ferritin-like TSH58p_11465 b90cf9ca95de57db7743b055dfc455ed 139 SUPERFAMILY SSF47240 3 138 2.25E-42 T 14-10-2018 IPR009078 Ferritin-like superfamily TSH58p_11465 b90cf9ca95de57db7743b055dfc455ed 139 Pfam PF02915 Rubrerythrin 11 133 1.1E-27 T 14-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TSH58p_01160 fbc6e0c4edc6aaad9dcdbc955251b0ab 395 TIGRFAM TIGR03863 PQQ_ABC_bind: ABC transporter, substrate binding protein, PQQ-dependent alcohol dehydrogenase system 45 392 1.1E-144 T 14-10-2018 IPR022478 ABC transporter, substrate-binding protein, PQQ-dependent alcohol dehydrogenase system TSH58p_01160 fbc6e0c4edc6aaad9dcdbc955251b0ab 395 Gene3D G3DSA:3.40.50.2300 276 355 1.6E-5 T 14-10-2018 TSH58p_01160 fbc6e0c4edc6aaad9dcdbc955251b0ab 395 Pfam PF13458 Periplasmic binding protein 52 210 4.9E-12 T 14-10-2018 IPR028081 Leucine-binding protein domain TSH58p_01160 fbc6e0c4edc6aaad9dcdbc955251b0ab 395 SUPERFAMILY SSF53822 51 358 1.18E-27 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_01160 fbc6e0c4edc6aaad9dcdbc955251b0ab 395 Gene3D G3DSA:3.40.50.2300 40 221 3.9E-12 T 14-10-2018 TSH58p_17315 6839fcc8b4ffacc3bdb258e3d72ca38c 350 PIRSF PIRSF002465 3 340 2.5E-121 T 14-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 TSH58p_17315 6839fcc8b4ffacc3bdb258e3d72ca38c 350 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 341 144.462 T 14-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 TSH58p_17315 6839fcc8b4ffacc3bdb258e3d72ca38c 350 Pfam PF02504 Fatty acid synthesis protein 6 327 2.4E-108 T 14-10-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 TSH58p_17315 6839fcc8b4ffacc3bdb258e3d72ca38c 350 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 6 336 6.0E-99 T 14-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 TSH58p_17315 6839fcc8b4ffacc3bdb258e3d72ca38c 350 Gene3D G3DSA:3.40.718.10 4 344 2.1E-123 T 14-10-2018 TSH58p_17315 6839fcc8b4ffacc3bdb258e3d72ca38c 350 SUPERFAMILY SSF53659 5 336 1.48E-103 T 14-10-2018 TSH58p_23450 857caad94f584f0e9f0c0ec8e583ce4d 545 ProSitePatterns PS00455 Putative AMP-binding domain signature. 193 204 - T 14-10-2018 IPR020845 AMP-binding, conserved site TSH58p_23450 857caad94f584f0e9f0c0ec8e583ce4d 545 TIGRFAM TIGR02275 DHB_AMP_lig: (2,3-dihydroxybenzoyl)adenylate synthase 4 530 6.8E-223 T 14-10-2018 IPR011963 2,3-dihydroxybenzoate-AMP ligase GO:0008668|GO:0019290 TSH58p_23450 857caad94f584f0e9f0c0ec8e583ce4d 545 SUPERFAMILY SSF56801 8 534 9.03E-128 T 14-10-2018 TSH58p_23450 857caad94f584f0e9f0c0ec8e583ce4d 545 Gene3D G3DSA:3.30.300.310 436 538 4.3E-31 T 14-10-2018 TSH58p_23450 857caad94f584f0e9f0c0ec8e583ce4d 545 Pfam PF00501 AMP-binding enzyme 39 440 5.1E-74 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_23450 857caad94f584f0e9f0c0ec8e583ce4d 545 Gene3D G3DSA:3.40.50.12780 2 434 4.6E-124 T 14-10-2018 TSH58p_23450 857caad94f584f0e9f0c0ec8e583ce4d 545 Pfam PF13193 AMP-binding enzyme C-terminal domain 449 523 4.4E-18 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSH58p_12430 eaf296cde7e2642637dd05fd9161c9ee 428 PIRSF PIRSF006066 1 428 6.4E-117 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSH58p_12430 eaf296cde7e2642637dd05fd9161c9ee 428 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 7 417 7.1E-89 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TSH58p_12430 eaf296cde7e2642637dd05fd9161c9ee 428 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 423 9.5E-107 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSH58p_26545 58033fd582a670b23d93cacc37069859 93 PIRSF PIRSF028784 2 93 6.6E-24 T 14-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 TSH58p_26545 58033fd582a670b23d93cacc37069859 93 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 35 86 6.4E-20 T 14-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 TSH58p_10435 04bd213ed5770e0f562ee730868eaca7 510 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 402 504 6.7E-29 T 14-10-2018 IPR025158 Mg chelatase-related protein, C-terminal domain TSH58p_10435 04bd213ed5770e0f562ee730868eaca7 510 SMART SM00382 209 391 5.4E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_10435 04bd213ed5770e0f562ee730868eaca7 510 Pfam PF13541 Subunit ChlI of Mg-chelatase 20 139 6.1E-38 T 14-10-2018 TSH58p_10435 04bd213ed5770e0f562ee730868eaca7 510 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 8 504 2.9E-155 T 14-10-2018 IPR004482 Mg chelatase-related protein TSH58p_10435 04bd213ed5770e0f562ee730868eaca7 510 SUPERFAMILY SSF54211 9 169 1.02E-22 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSH58p_10435 04bd213ed5770e0f562ee730868eaca7 510 Gene3D G3DSA:3.40.50.300 190 507 1.3E-51 T 14-10-2018 TSH58p_10435 04bd213ed5770e0f562ee730868eaca7 510 SUPERFAMILY SSF52540 187 505 4.94E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_10435 04bd213ed5770e0f562ee730868eaca7 510 Pfam PF01078 Magnesium chelatase, subunit ChlI 189 393 2.2E-93 T 14-10-2018 IPR000523 Magnesium chelatase ChlI domain TSH58p_03910 42e30e68c0cbdaa20f5ed54aa89cd7b0 435 Gene3D G3DSA:1.10.287.950 138 430 1.6E-53 T 14-10-2018 TSH58p_03910 42e30e68c0cbdaa20f5ed54aa89cd7b0 435 SMART SM00283 173 427 9.8E-47 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_03910 42e30e68c0cbdaa20f5ed54aa89cd7b0 435 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 271 298 3.1E-22 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_03910 42e30e68c0cbdaa20f5ed54aa89cd7b0 435 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 348 377 3.1E-22 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_03910 42e30e68c0cbdaa20f5ed54aa89cd7b0 435 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 194 223 3.1E-22 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_03910 42e30e68c0cbdaa20f5ed54aa89cd7b0 435 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 300 329 3.1E-22 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_03910 42e30e68c0cbdaa20f5ed54aa89cd7b0 435 SUPERFAMILY SSF58104 82 426 5.36E-54 T 14-10-2018 TSH58p_03910 42e30e68c0cbdaa20f5ed54aa89cd7b0 435 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 241 403 2.0E-32 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_16375 676f3debbc870a377f4fbe4aa678a2b2 146 Gene3D G3DSA:3.40.630.30 38 141 2.5E-25 T 14-10-2018 TSH58p_16375 676f3debbc870a377f4fbe4aa678a2b2 146 Pfam PF00583 Acetyltransferase (GNAT) family 45 119 3.8E-9 T 14-10-2018 IPR000182 GNAT domain TSH58p_16375 676f3debbc870a377f4fbe4aa678a2b2 146 SUPERFAMILY SSF55729 13 141 2.03E-24 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_27945 a577a8a13717ee967bab04957eaf656d 222 Pfam PF13462 Thioredoxin 52 219 1.5E-39 T 14-10-2018 IPR012336 Thioredoxin-like fold TSH58p_27945 a577a8a13717ee967bab04957eaf656d 222 Gene3D G3DSA:3.40.30.10 37 222 1.3E-44 T 14-10-2018 TSH58p_27945 a577a8a13717ee967bab04957eaf656d 222 ProSitePatterns PS00194 Thioredoxin family active site. 65 83 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 TSH58p_27945 a577a8a13717ee967bab04957eaf656d 222 SUPERFAMILY SSF52833 47 218 3.97E-36 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_31645 8fbfcca3b07ef014bd50976f5d0bd6cc 221 SMART SM00903 20 166 1.5E-14 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 TSH58p_31645 8fbfcca3b07ef014bd50976f5d0bd6cc 221 Gene3D G3DSA:2.30.110.10 1 213 7.9E-64 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TSH58p_31645 8fbfcca3b07ef014bd50976f5d0bd6cc 221 Pfam PF01613 Flavin reductase like domain 23 162 4.4E-18 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 TSH58p_31645 8fbfcca3b07ef014bd50976f5d0bd6cc 221 SUPERFAMILY SSF50475 2 194 3.88E-41 T 14-10-2018 TSH58p_06365 6e3235cb3a487e1280056b925b1b4dd2 1115 Gene3D G3DSA:1.20.58.280 560 635 6.4E-46 T 14-10-2018 TSH58p_06365 6e3235cb3a487e1280056b925b1b4dd2 1115 SMART SM00642 3 337 1.1E-6 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSH58p_06365 6e3235cb3a487e1280056b925b1b4dd2 1115 SUPERFAMILY SSF51445 651 1015 3.73E-81 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_06365 6e3235cb3a487e1280056b925b1b4dd2 1115 Gene3D G3DSA:2.60.40.1180 1020 1115 4.8E-26 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta TSH58p_06365 6e3235cb3a487e1280056b925b1b4dd2 1115 SUPERFAMILY SSF51445 7 343 6.28E-57 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_06365 6e3235cb3a487e1280056b925b1b4dd2 1115 Pfam PF00128 Alpha amylase, catalytic domain 679 785 4.0E-5 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSH58p_06365 6e3235cb3a487e1280056b925b1b4dd2 1115 Pfam PF14701 Glycogen debranching enzyme, glucanotransferase domain 11 111 3.7E-11 T 14-10-2018 IPR032792 Glycogen debranching enzyme, glucanotransferase domain KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-6798695|Reactome: R-HSA-70221 TSH58p_06365 6e3235cb3a487e1280056b925b1b4dd2 1115 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 470 1112 45.708 T 14-10-2018 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16|MetaCyc: PWY-7900 TSH58p_06365 6e3235cb3a487e1280056b925b1b4dd2 1115 Gene3D G3DSA:3.20.20.80 5 345 1.1E-69 T 14-10-2018 TSH58p_06365 6e3235cb3a487e1280056b925b1b4dd2 1115 Gene3D G3DSA:3.20.20.80 656 1019 4.6E-150 T 14-10-2018 TSH58p_06365 6e3235cb3a487e1280056b925b1b4dd2 1115 Gene3D G3DSA:2.60.40.10 473 655 6.4E-46 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_06365 6e3235cb3a487e1280056b925b1b4dd2 1115 Pfam PF11896 Domain of unknown function (DUF3416) 472 655 1.0E-51 T 14-10-2018 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16|MetaCyc: PWY-7900 TSH58p_18605 a14b4dab67adec511c51cd5efaf4a846 321 Gene3D G3DSA:3.40.190.10 123 247 2.6E-73 T 14-10-2018 TSH58p_18605 a14b4dab67adec511c51cd5efaf4a846 321 PIRSF PIRSF017082 3 321 6.3E-97 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 TSH58p_18605 a14b4dab67adec511c51cd5efaf4a846 321 SUPERFAMILY SSF53850 34 275 3.33E-11 T 14-10-2018 TSH58p_18605 a14b4dab67adec511c51cd5efaf4a846 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 317 1.7E-30 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 TSH58p_18605 a14b4dab67adec511c51cd5efaf4a846 321 Gene3D G3DSA:3.40.190.150 31 310 2.6E-73 T 14-10-2018 TSH58p_22610 0b5e9416f27f859fdd498cedeb97c42e 69 Pfam PF01471 Putative peptidoglycan binding domain 11 65 1.7E-14 T 14-10-2018 IPR002477 Peptidoglycan binding-like TSH58p_22610 0b5e9416f27f859fdd498cedeb97c42e 69 Gene3D G3DSA:1.10.101.10 2 68 1.9E-15 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 TSH58p_22610 0b5e9416f27f859fdd498cedeb97c42e 69 SUPERFAMILY SSF47090 7 67 9.42E-16 T 14-10-2018 IPR036365 PGBD-like superfamily TSH58p_04380 cba16e5776c11d0187c37f0effe425f6 370 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 62 118 8.7E-8 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 TSH58p_04380 cba16e5776c11d0187c37f0effe425f6 370 Pfam PF14657 Arm DNA-binding domain 19 52 2.8E-5 T 14-10-2018 IPR028259 AP2-like integrase, N-terminal domain TSH58p_04380 cba16e5776c11d0187c37f0effe425f6 370 Gene3D G3DSA:1.10.443.10 168 362 5.2E-45 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TSH58p_04380 cba16e5776c11d0187c37f0effe425f6 370 Pfam PF00589 Phage integrase family 185 349 2.1E-24 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TSH58p_04380 cba16e5776c11d0187c37f0effe425f6 370 Gene3D G3DSA:1.10.150.130 57 167 2.3E-19 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal TSH58p_04380 cba16e5776c11d0187c37f0effe425f6 370 SUPERFAMILY SSF56349 61 357 1.35E-60 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TSH58p_03290 560705c039b250e7360b81f4613457be 537 Gene3D G3DSA:3.20.20.80 7 447 4.4E-178 T 14-10-2018 TSH58p_03290 560705c039b250e7360b81f4613457be 537 SMART SM00642 15 394 9.4E-133 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSH58p_03290 560705c039b250e7360b81f4613457be 537 SUPERFAMILY SSF51011 455 527 3.91E-6 T 14-10-2018 TSH58p_03290 560705c039b250e7360b81f4613457be 537 Pfam PF00128 Alpha amylase, catalytic domain 30 369 2.8E-92 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSH58p_03290 560705c039b250e7360b81f4613457be 537 Gene3D G3DSA:3.90.400.10 107 177 4.4E-178 T 14-10-2018 TSH58p_03290 560705c039b250e7360b81f4613457be 537 SUPERFAMILY SSF51445 6 452 8.33E-145 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_03290 560705c039b250e7360b81f4613457be 537 Pfam PF11941 Domain of unknown function (DUF3459) 438 526 1.1E-10 T 14-10-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) TSH58p_00200 03ce92e84cbb08cb8b0d456171f8ffa3 591 Pfam PF00733 Asparagine synthase 245 587 4.1E-91 T 14-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 TSH58p_00200 03ce92e84cbb08cb8b0d456171f8ffa3 591 SUPERFAMILY SSF56235 1 224 8.06E-61 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_00200 03ce92e84cbb08cb8b0d456171f8ffa3 591 TIGRFAM TIGR03104 trio_amidotrans: asparagine synthase family amidotransferase 1 589 0.0 T 14-10-2018 IPR017535 Asparagine synthase family amidotransferase TSH58p_00200 03ce92e84cbb08cb8b0d456171f8ffa3 591 SUPERFAMILY SSF52402 236 567 1.9E-80 T 14-10-2018 TSH58p_00200 03ce92e84cbb08cb8b0d456171f8ffa3 591 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 520 4.2E-136 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 TSH58p_00200 03ce92e84cbb08cb8b0d456171f8ffa3 591 Gene3D G3DSA:3.60.20.10 4 186 3.4E-58 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_00200 03ce92e84cbb08cb8b0d456171f8ffa3 591 Pfam PF13537 Glutamine amidotransferase domain 47 167 1.8E-43 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain TSH58p_00200 03ce92e84cbb08cb8b0d456171f8ffa3 591 PIRSF PIRSF001589 1 591 2.3E-220 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 TSH58p_23980 ef73e5edc16e2b2279f136bd76e085f6 447 SUPERFAMILY SSF58104 193 440 5.93E-56 T 14-10-2018 TSH58p_23980 ef73e5edc16e2b2279f136bd76e085f6 447 Gene3D G3DSA:1.10.287.950 166 446 2.0E-46 T 14-10-2018 TSH58p_23980 ef73e5edc16e2b2279f136bd76e085f6 447 SMART SM00283 194 441 7.1E-35 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_23980 ef73e5edc16e2b2279f136bd76e085f6 447 Gene3D G3DSA:1.10.490.10 6 165 4.0E-17 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 TSH58p_23980 ef73e5edc16e2b2279f136bd76e085f6 447 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 314 343 9.1E-22 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_23980 ef73e5edc16e2b2279f136bd76e085f6 447 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 285 312 9.1E-22 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_23980 ef73e5edc16e2b2279f136bd76e085f6 447 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 362 391 9.1E-22 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_23980 ef73e5edc16e2b2279f136bd76e085f6 447 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 204 233 9.1E-22 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_23980 ef73e5edc16e2b2279f136bd76e085f6 447 Pfam PF11563 Protoglobin 7 163 6.1E-14 T 14-10-2018 TSH58p_23980 ef73e5edc16e2b2279f136bd76e085f6 447 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 249 409 7.0E-29 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_23980 ef73e5edc16e2b2279f136bd76e085f6 447 SUPERFAMILY SSF46458 3 155 3.02E-9 T 14-10-2018 IPR009050 Globin-like superfamily TSH58p_03590 d36dca008b2d68037e65203a2696c189 3252 Pfam PF01464 Transglycosylase SLT domain 1467 1553 2.4E-20 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 TSH58p_03590 d36dca008b2d68037e65203a2696c189 3252 Pfam PF06791 Prophage tail length tape measure protein 642 836 1.2E-37 T 14-10-2018 IPR009628 Bacteriophage lambda, GpH, tail tape measure, N-terminal TSH58p_03590 d36dca008b2d68037e65203a2696c189 3252 SUPERFAMILY SSF53955 1458 1575 2.51E-27 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily TSH58p_03590 d36dca008b2d68037e65203a2696c189 3252 Gene3D G3DSA:1.10.530.10 1462 1590 1.3E-24 T 14-10-2018 TSH58p_16115 a78784d6e61239491d580a775b1180c2 163 Pfam PF00075 RNase H 16 154 1.9E-51 T 14-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 TSH58p_16115 a78784d6e61239491d580a775b1180c2 163 SUPERFAMILY SSF53098 16 154 2.53E-59 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily TSH58p_16115 a78784d6e61239491d580a775b1180c2 163 Gene3D G3DSA:3.30.420.10 11 161 8.6E-62 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TSH58p_16115 a78784d6e61239491d580a775b1180c2 163 Hamap MF_00042 Ribonuclease H [rnhA]. 15 163 35.987 T 14-10-2018 IPR022892 Ribonuclease HI GO:0004523 TSH58p_09665 368dac922ae321db06bf782dedb8fe0a 385 Gene3D G3DSA:3.60.40.10 138 384 3.0E-47 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSH58p_09665 368dac922ae321db06bf782dedb8fe0a 385 SMART SM00331 169 383 2.2E-14 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSH58p_09665 368dac922ae321db06bf782dedb8fe0a 385 Pfam PF00072 Response regulator receiver domain 10 122 1.4E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_09665 368dac922ae321db06bf782dedb8fe0a 385 SMART SM00448 8 122 1.8E-37 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_09665 368dac922ae321db06bf782dedb8fe0a 385 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 196 383 2.7E-32 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSH58p_09665 368dac922ae321db06bf782dedb8fe0a 385 SUPERFAMILY SSF52172 9 149 1.42E-39 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_09665 368dac922ae321db06bf782dedb8fe0a 385 Gene3D G3DSA:3.40.50.2300 5 137 5.5E-39 T 14-10-2018 TSH58p_25845 601a7a967fa90c23d32ba7fc2e3fa33f 329 Gene3D G3DSA:3.40.50.720 8 284 3.2E-52 T 14-10-2018 TSH58p_25845 601a7a967fa90c23d32ba7fc2e3fa33f 329 SUPERFAMILY SSF51735 7 262 1.17E-54 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_25845 601a7a967fa90c23d32ba7fc2e3fa33f 329 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 216 7.6E-17 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TSH58p_03840 c04c834bf74e8f309cf549da17411276 102 Pfam PF02036 SCP-2 sterol transfer family 5 101 3.2E-18 T 14-10-2018 IPR003033 SCP2 sterol-binding domain TSH58p_03840 c04c834bf74e8f309cf549da17411276 102 SUPERFAMILY SSF55718 15 101 3.14E-19 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily TSH58p_03840 c04c834bf74e8f309cf549da17411276 102 Gene3D G3DSA:3.30.1050.10 1 102 1.7E-21 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily TSH58p_09625 38b5eac14819f6b2fd3475108a32101e 388 SUPERFAMILY SSF58104 67 318 9.81E-33 T 14-10-2018 TSH58p_09625 38b5eac14819f6b2fd3475108a32101e 388 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 144 289 5.0E-24 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_09625 38b5eac14819f6b2fd3475108a32101e 388 SMART SM00283 65 315 3.8E-5 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_09625 38b5eac14819f6b2fd3475108a32101e 388 Gene3D G3DSA:1.10.287.950 51 327 8.3E-36 T 14-10-2018 TSH58p_25560 c7a68d96bfb92c1beaafcf1a4efcf793 821 PIRSF PIRSF037149 6 820 0.0 T 14-10-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 TSH58p_25560 c7a68d96bfb92c1beaafcf1a4efcf793 821 Gene3D G3DSA:3.30.390.30 324 383 3.3E-8 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TSH58p_25560 c7a68d96bfb92c1beaafcf1a4efcf793 821 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 14 797 3.7E-289 T 14-10-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 TSH58p_25560 c7a68d96bfb92c1beaafcf1a4efcf793 821 SUPERFAMILY SSF51905 155 313 1.91E-26 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_25560 c7a68d96bfb92c1beaafcf1a4efcf793 821 Gene3D G3DSA:3.50.50.60 118 252 1.4E-89 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_25560 c7a68d96bfb92c1beaafcf1a4efcf793 821 SUPERFAMILY SSF56014 643 810 2.36E-51 T 14-10-2018 TSH58p_25560 c7a68d96bfb92c1beaafcf1a4efcf793 821 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 13 289 7.5E-51 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSH58p_25560 c7a68d96bfb92c1beaafcf1a4efcf793 821 Pfam PF04324 BFD-like [2Fe-2S] binding domain 429 477 1.6E-12 T 14-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain TSH58p_25560 c7a68d96bfb92c1beaafcf1a4efcf793 821 Pfam PF04324 BFD-like [2Fe-2S] binding domain 493 542 4.7E-13 T 14-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain TSH58p_25560 c7a68d96bfb92c1beaafcf1a4efcf793 821 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 642 775 2.2E-24 T 14-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TSH58p_25560 c7a68d96bfb92c1beaafcf1a4efcf793 821 SUPERFAMILY SSF51905 9 200 1.94E-43 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_25560 c7a68d96bfb92c1beaafcf1a4efcf793 821 Gene3D G3DSA:1.10.10.1100 428 482 8.2E-9 T 14-10-2018 TSH58p_25560 c7a68d96bfb92c1beaafcf1a4efcf793 821 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 688 704 - T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TSH58p_25560 c7a68d96bfb92c1beaafcf1a4efcf793 821 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 1.3E-17 T 14-10-2018 TSH58p_25560 c7a68d96bfb92c1beaafcf1a4efcf793 821 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 287 1.3E-17 T 14-10-2018 TSH58p_25560 c7a68d96bfb92c1beaafcf1a4efcf793 821 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 14 33 1.3E-17 T 14-10-2018 TSH58p_25560 c7a68d96bfb92c1beaafcf1a4efcf793 821 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 240 256 1.3E-17 T 14-10-2018 TSH58p_25560 c7a68d96bfb92c1beaafcf1a4efcf793 821 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 110 128 1.3E-17 T 14-10-2018 TSH58p_25560 c7a68d96bfb92c1beaafcf1a4efcf793 821 SUPERFAMILY SSF55124 527 650 7.03E-27 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TSH58p_25560 c7a68d96bfb92c1beaafcf1a4efcf793 821 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 568 632 1.9E-14 T 14-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TSH58p_25560 c7a68d96bfb92c1beaafcf1a4efcf793 821 Gene3D G3DSA:3.50.50.60 15 288 1.4E-89 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_25560 c7a68d96bfb92c1beaafcf1a4efcf793 821 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 13 35 1.1E-9 T 14-10-2018 TSH58p_25560 c7a68d96bfb92c1beaafcf1a4efcf793 821 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 241 255 1.1E-9 T 14-10-2018 TSH58p_25560 c7a68d96bfb92c1beaafcf1a4efcf793 821 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 280 287 1.1E-9 T 14-10-2018 TSH58p_25560 c7a68d96bfb92c1beaafcf1a4efcf793 821 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 180 1.1E-9 T 14-10-2018 TSH58p_25560 c7a68d96bfb92c1beaafcf1a4efcf793 821 Gene3D G3DSA:3.30.413.10 641 802 6.6E-33 T 14-10-2018 TSH58p_25560 c7a68d96bfb92c1beaafcf1a4efcf793 821 PRINTS PR00397 Sirohaem Fe-binding site signature 645 663 1.4E-6 T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TSH58p_25560 c7a68d96bfb92c1beaafcf1a4efcf793 821 PRINTS PR00397 Sirohaem Fe-binding site signature 688 706 1.4E-6 T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TSH58p_15600 58ad02fc578e0dcdbc660b19ec8a561a 188 Gene3D G3DSA:1.10.1740.10 18 85 2.6E-19 T 14-10-2018 TSH58p_15600 58ad02fc578e0dcdbc660b19ec8a561a 188 Pfam PF04542 Sigma-70 region 2 30 93 5.3E-10 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_15600 58ad02fc578e0dcdbc660b19ec8a561a 188 Gene3D G3DSA:1.10.10.10 114 178 5.4E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_15600 58ad02fc578e0dcdbc660b19ec8a561a 188 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 30 175 6.6E-19 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TSH58p_15600 58ad02fc578e0dcdbc660b19ec8a561a 188 SUPERFAMILY SSF88946 26 101 3.73E-15 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_15600 58ad02fc578e0dcdbc660b19ec8a561a 188 Pfam PF08281 Sigma-70, region 4 122 172 3.9E-16 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_15600 58ad02fc578e0dcdbc660b19ec8a561a 188 SUPERFAMILY SSF88659 116 177 6.32E-17 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSH58p_22860 ee798b3f14a04779390e6b206ce27a97 492 PIRSF PIRSF000130 1 492 3.2E-206 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 TSH58p_22860 ee798b3f14a04779390e6b206ce27a97 492 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 300 312 - T 14-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 TSH58p_22860 ee798b3f14a04779390e6b206ce27a97 492 Pfam PF00571 CBS domain 156 206 1.4E-8 T 14-10-2018 IPR000644 CBS domain TSH58p_22860 ee798b3f14a04779390e6b206ce27a97 492 Pfam PF00571 CBS domain 95 148 3.0E-11 T 14-10-2018 IPR000644 CBS domain TSH58p_22860 ee798b3f14a04779390e6b206ce27a97 492 SUPERFAMILY SSF51412 6 482 4.71E-125 T 14-10-2018 TSH58p_22860 ee798b3f14a04779390e6b206ce27a97 492 SMART SM01240 9 478 0.0 T 14-10-2018 TSH58p_22860 ee798b3f14a04779390e6b206ce27a97 492 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 10 491 84.995 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 TSH58p_22860 ee798b3f14a04779390e6b206ce27a97 492 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 10 478 5.5E-163 T 14-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 TSH58p_22860 ee798b3f14a04779390e6b206ce27a97 492 SUPERFAMILY SSF54631 65 209 6.57E-31 T 14-10-2018 TSH58p_22860 ee798b3f14a04779390e6b206ce27a97 492 SMART SM00116 98 151 1.9E-12 T 14-10-2018 IPR000644 CBS domain TSH58p_22860 ee798b3f14a04779390e6b206ce27a97 492 SMART SM00116 163 211 5.6E-7 T 14-10-2018 IPR000644 CBS domain TSH58p_22860 ee798b3f14a04779390e6b206ce27a97 492 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 10 459 9.8E-199 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 TSH58p_22860 ee798b3f14a04779390e6b206ce27a97 492 Gene3D G3DSA:3.20.20.70 2 491 3.7E-215 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_12860 961e9a5792f2f4064d243dfefb8ef634 374 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 18 360 2.4E-108 T 14-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 TSH58p_12860 961e9a5792f2f4064d243dfefb8ef634 374 Gene3D G3DSA:3.40.50.1970 1 179 1.4E-60 T 14-10-2018 TSH58p_12860 961e9a5792f2f4064d243dfefb8ef634 374 SUPERFAMILY SSF56796 12 369 4.19E-107 T 14-10-2018 TSH58p_12860 961e9a5792f2f4064d243dfefb8ef634 374 PIRSF PIRSF001455 9 373 4.1E-102 T 14-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 TSH58p_12860 961e9a5792f2f4064d243dfefb8ef634 374 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 6 368 67.48 T 14-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 TSH58p_12860 961e9a5792f2f4064d243dfefb8ef634 374 Pfam PF01761 3-dehydroquinate synthase 74 337 3.9E-99 T 14-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 TSH58p_12860 961e9a5792f2f4064d243dfefb8ef634 374 Gene3D G3DSA:1.20.1090.10 180 373 3.5E-59 T 14-10-2018 TSH58p_11990 3158f582615421426340dfb4c41daa68 194 SUPERFAMILY SSF75217 6 145 9.81E-28 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases TSH58p_11990 3158f582615421426340dfb4c41daa68 194 Gene3D G3DSA:3.40.1280.10 7 145 3.9E-25 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TSH58p_11990 3158f582615421426340dfb4c41daa68 194 Pfam PF00588 SpoU rRNA Methylase family 6 139 7.0E-21 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TSH58p_13565 d14e036c54bea86f72ddf0749e3de065 207 Gene3D G3DSA:3.40.50.300 4 207 8.8E-36 T 14-10-2018 TSH58p_13565 d14e036c54bea86f72ddf0749e3de065 207 PIRSF PIRSF009320 1 206 1.9E-23 T 14-10-2018 TSH58p_13565 d14e036c54bea86f72ddf0749e3de065 207 SUPERFAMILY SSF52540 1 204 2.01E-29 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_13565 d14e036c54bea86f72ddf0749e3de065 207 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 179 5.8E-12 T 14-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TSH58p_19340 3c51c54fdbcdc0bd84c76485239ef97b 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.7E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_19340 3c51c54fdbcdc0bd84c76485239ef97b 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.7E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_19340 3c51c54fdbcdc0bd84c76485239ef97b 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.7E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_19340 3c51c54fdbcdc0bd84c76485239ef97b 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 247 1.5E-63 T 14-10-2018 TSH58p_19340 3c51c54fdbcdc0bd84c76485239ef97b 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_19340 3c51c54fdbcdc0bd84c76485239ef97b 250 Gene3D G3DSA:3.40.50.720 1 250 2.5E-81 T 14-10-2018 TSH58p_19340 3c51c54fdbcdc0bd84c76485239ef97b 250 SUPERFAMILY SSF51735 6 249 9.49E-82 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_19340 3c51c54fdbcdc0bd84c76485239ef97b 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 3.2E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_19340 3c51c54fdbcdc0bd84c76485239ef97b 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 3.2E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_19340 3c51c54fdbcdc0bd84c76485239ef97b 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 3.2E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_19340 3c51c54fdbcdc0bd84c76485239ef97b 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.2E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_19340 3c51c54fdbcdc0bd84c76485239ef97b 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 3.2E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_19340 3c51c54fdbcdc0bd84c76485239ef97b 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 3.2E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_01275 a9b04c5ab5a55f03d0a3441fd0c374d4 211 SUPERFAMILY SSF46894 141 201 2.76E-17 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_01275 a9b04c5ab5a55f03d0a3441fd0c374d4 211 Gene3D G3DSA:3.40.50.2300 5 137 6.8E-44 T 14-10-2018 TSH58p_01275 a9b04c5ab5a55f03d0a3441fd0c374d4 211 SUPERFAMILY SSF52172 10 158 8.97E-31 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_01275 a9b04c5ab5a55f03d0a3441fd0c374d4 211 SMART SM00421 145 202 1.1E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_01275 a9b04c5ab5a55f03d0a3441fd0c374d4 211 SMART SM00448 10 121 9.7E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_01275 a9b04c5ab5a55f03d0a3441fd0c374d4 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 8.7E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_01275 a9b04c5ab5a55f03d0a3441fd0c374d4 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 8.7E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_01275 a9b04c5ab5a55f03d0a3441fd0c374d4 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 8.7E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_01275 a9b04c5ab5a55f03d0a3441fd0c374d4 211 Pfam PF00072 Response regulator receiver domain 12 121 1.8E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_01275 a9b04c5ab5a55f03d0a3441fd0c374d4 211 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 201 2.4E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_01275 a9b04c5ab5a55f03d0a3441fd0c374d4 211 Gene3D G3DSA:1.10.10.10 140 202 6.7E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_15580 8a9aa59698b871aa2e0db1c26fc75c3e 236 SUPERFAMILY SSF48097 119 201 1.25E-7 T 14-10-2018 IPR036305 RGS domain superfamily TSH58p_15580 8a9aa59698b871aa2e0db1c26fc75c3e 236 Gene3D G3DSA:1.20.58.1850 114 217 7.7E-6 T 14-10-2018 TSH58p_28200 494db8424e44d1d78b61b21485670081 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 228 5.5E-19 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_28200 494db8424e44d1d78b61b21485670081 232 SMART SM00448 7 117 1.1E-43 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_28200 494db8424e44d1d78b61b21485670081 232 Pfam PF00072 Response regulator receiver domain 9 117 9.7E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_28200 494db8424e44d1d78b61b21485670081 232 SUPERFAMILY SSF46894 133 230 2.38E-20 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_28200 494db8424e44d1d78b61b21485670081 232 Gene3D G3DSA:1.10.10.10 127 231 1.7E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_28200 494db8424e44d1d78b61b21485670081 232 SUPERFAMILY SSF52172 5 128 1.25E-41 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_28200 494db8424e44d1d78b61b21485670081 232 Gene3D G3DSA:3.40.50.2300 1 126 9.1E-39 T 14-10-2018 TSH58p_28200 494db8424e44d1d78b61b21485670081 232 SMART SM00862 155 228 4.7E-20 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_00070 3895e31709af1ffae41553f9ac78bd3f 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 46 62 2.7E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_00070 3895e31709af1ffae41553f9ac78bd3f 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 78 2.7E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_00070 3895e31709af1ffae41553f9ac78bd3f 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 82 98 2.7E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_00070 3895e31709af1ffae41553f9ac78bd3f 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 112 132 2.7E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_00070 3895e31709af1ffae41553f9ac78bd3f 144 Pfam PF12802 MarR family 28 85 1.1E-14 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_00070 3895e31709af1ffae41553f9ac78bd3f 144 Gene3D G3DSA:1.10.10.10 1 136 3.0E-37 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_00070 3895e31709af1ffae41553f9ac78bd3f 144 SMART SM00347 22 122 1.4E-18 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_00070 3895e31709af1ffae41553f9ac78bd3f 144 SUPERFAMILY SSF46785 2 135 5.79E-32 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_05255 8ece346d45672cd3eda797068e73f512 424 Gene3D G3DSA:3.40.640.10 65 296 1.0E-121 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_05255 8ece346d45672cd3eda797068e73f512 424 Gene3D G3DSA:3.90.1150.10 297 394 1.0E-121 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_05255 8ece346d45672cd3eda797068e73f512 424 SUPERFAMILY SSF53383 6 398 6.8E-110 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_05255 8ece346d45672cd3eda797068e73f512 424 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 244 257 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TSH58p_05255 8ece346d45672cd3eda797068e73f512 424 Pfam PF00155 Aminotransferase class I and II 33 379 5.5E-58 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSH58p_09025 f26a71cb556d3782f75791c594e121b8 307 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 299 8.0E-70 T 14-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 TSH58p_09025 f26a71cb556d3782f75791c594e121b8 307 SUPERFAMILY SSF48179 180 300 1.12E-24 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_09025 f26a71cb556d3782f75791c594e121b8 307 Gene3D G3DSA:3.40.50.720 1 177 2.6E-59 T 14-10-2018 TSH58p_09025 f26a71cb556d3782f75791c594e121b8 307 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 153 5.3E-40 T 14-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain TSH58p_09025 f26a71cb556d3782f75791c594e121b8 307 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 180 300 2.7E-24 T 14-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain TSH58p_09025 f26a71cb556d3782f75791c594e121b8 307 Gene3D G3DSA:1.10.1040.10 180 307 1.4E-28 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSH58p_09025 f26a71cb556d3782f75791c594e121b8 307 SUPERFAMILY SSF51735 1 155 1.5E-15 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_24695 8b94f444b56ea74c01c0eef320389931 142 Pfam PF13404 AsnC-type helix-turn-helix domain 1 41 8.0E-12 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSH58p_24695 8b94f444b56ea74c01c0eef320389931 142 Pfam PF01037 Lrp/AsnC ligand binding domain 68 136 9.6E-16 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TSH58p_24695 8b94f444b56ea74c01c0eef320389931 142 SMART SM00344 1 107 3.9E-15 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TSH58p_24695 8b94f444b56ea74c01c0eef320389931 142 Gene3D G3DSA:1.10.10.10 1 53 1.3E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_24695 8b94f444b56ea74c01c0eef320389931 142 SUPERFAMILY SSF46785 1 55 1.54E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_24695 8b94f444b56ea74c01c0eef320389931 142 SUPERFAMILY SSF54909 63 139 6.97E-16 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel TSH58p_24695 8b94f444b56ea74c01c0eef320389931 142 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 3.0E-7 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSH58p_24695 8b94f444b56ea74c01c0eef320389931 142 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 3.0E-7 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TSH58p_24695 8b94f444b56ea74c01c0eef320389931 142 Gene3D G3DSA:3.30.70.920 62 133 1.8E-17 T 14-10-2018 TSH58p_22830 f9ac0cc85446281a8f7aa2a639231919 455 Gene3D G3DSA:3.40.50.150 130 432 2.7E-86 T 14-10-2018 TSH58p_22830 f9ac0cc85446281a8f7aa2a639231919 455 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 309 320 - T 14-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 TSH58p_22830 f9ac0cc85446281a8f7aa2a639231919 455 SUPERFAMILY SSF53335 125 432 4.37E-74 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_22830 f9ac0cc85446281a8f7aa2a639231919 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 415 432 1.4E-29 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSH58p_22830 f9ac0cc85446281a8f7aa2a639231919 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 241 251 1.4E-29 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSH58p_22830 f9ac0cc85446281a8f7aa2a639231919 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 212 226 1.4E-29 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSH58p_22830 f9ac0cc85446281a8f7aa2a639231919 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 360 376 1.4E-29 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSH58p_22830 f9ac0cc85446281a8f7aa2a639231919 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 310 322 1.4E-29 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSH58p_22830 f9ac0cc85446281a8f7aa2a639231919 455 Pfam PF01189 16S rRNA methyltransferase RsmB/F 230 429 3.1E-51 T 14-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 TSH58p_13150 6be58a65683e9f6f0276f1ed2dcc89d8 117 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 82 3.5E-31 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_13150 6be58a65683e9f6f0276f1ed2dcc89d8 117 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 14-10-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_13150 6be58a65683e9f6f0276f1ed2dcc89d8 117 Pfam PF00886 Ribosomal protein S16 9 70 4.5E-27 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_13150 6be58a65683e9f6f0276f1ed2dcc89d8 117 Gene3D G3DSA:3.30.1320.10 1 117 4.4E-39 T 14-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_13150 6be58a65683e9f6f0276f1ed2dcc89d8 117 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 80 23.795 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_13150 6be58a65683e9f6f0276f1ed2dcc89d8 117 SUPERFAMILY SSF54565 3 96 5.23E-32 T 14-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_30500 b9b97ca16131477451c5930560ac2207 267 SUPERFAMILY SSF51735 11 264 5.44E-76 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_30500 b9b97ca16131477451c5930560ac2207 267 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 27 263 1.1E-60 T 14-10-2018 TSH58p_30500 b9b97ca16131477451c5930560ac2207 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 2.2E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30500 b9b97ca16131477451c5930560ac2207 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 2.2E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30500 b9b97ca16131477451c5930560ac2207 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 2.2E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30500 b9b97ca16131477451c5930560ac2207 267 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_30500 b9b97ca16131477451c5930560ac2207 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 9.7E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30500 b9b97ca16131477451c5930560ac2207 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 9.7E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30500 b9b97ca16131477451c5930560ac2207 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 9.7E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30500 b9b97ca16131477451c5930560ac2207 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 226 246 9.7E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30500 b9b97ca16131477451c5930560ac2207 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 9.7E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30500 b9b97ca16131477451c5930560ac2207 267 Gene3D G3DSA:3.40.50.720 1 264 2.5E-80 T 14-10-2018 TSH58p_19055 c90b77a4be05698267537e3f740878bd 259 SUPERFAMILY SSF102114 40 226 5.69E-26 T 14-10-2018 TSH58p_19055 c90b77a4be05698267537e3f740878bd 259 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 23 253 6.6E-91 T 14-10-2018 IPR012838 Pyruvate formate-lyase 1 activating enzyme GO:0043365|GO:0055114 TSH58p_19055 c90b77a4be05698267537e3f740878bd 259 ProSitePatterns PS01087 Radical activating enzymes signature. 34 55 - T 14-10-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 TSH58p_19055 c90b77a4be05698267537e3f740878bd 259 Gene3D G3DSA:3.20.20.70 18 259 1.4E-81 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_19055 c90b77a4be05698267537e3f740878bd 259 Pfam PF13353 4Fe-4S single cluster domain 32 144 6.7E-16 T 14-10-2018 TSH58p_19055 c90b77a4be05698267537e3f740878bd 259 Pfam PF04055 Radical SAM superfamily 42 200 8.5E-22 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSH58p_19055 c90b77a4be05698267537e3f740878bd 259 PIRSF PIRSF000371 61 259 3.0E-37 T 14-10-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 TSH58p_19055 c90b77a4be05698267537e3f740878bd 259 PIRSF PIRSF000371 17 65 1.2E-12 T 14-10-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 TSH58p_23250 ff64ebaab756860229698469f5e9f31d 363 SUPERFAMILY SSF50331 238 358 1.07E-17 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSH58p_23250 ff64ebaab756860229698469f5e9f31d 363 SUPERFAMILY SSF52540 10 226 6.44E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_23250 ff64ebaab756860229698469f5e9f31d 363 Gene3D G3DSA:3.40.50.300 3 240 8.3E-55 T 14-10-2018 TSH58p_23250 ff64ebaab756860229698469f5e9f31d 363 SMART SM00382 24 210 4.8E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_23250 ff64ebaab756860229698469f5e9f31d 363 TIGRFAM TIGR02142 modC_ABC: molybdate ABC transporter, ATP-binding protein 3 358 1.2E-131 T 14-10-2018 IPR011868 Molybdate ABC transporter, ATP-binding protein GO:0005524|GO:0015098|GO:0015689|GO:0016020 TSH58p_23250 ff64ebaab756860229698469f5e9f31d 363 Pfam PF00005 ABC transporter 21 160 1.1E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_23250 ff64ebaab756860229698469f5e9f31d 363 Gene3D G3DSA:2.40.50.100 293 359 3.8E-11 T 14-10-2018 TSH58p_23250 ff64ebaab756860229698469f5e9f31d 363 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_23250 ff64ebaab756860229698469f5e9f31d 363 Pfam PF03459 TOBE domain 293 357 4.1E-12 T 14-10-2018 IPR005116 Transport-associated OB, type 1 TSH58p_08910 c9db81a5178e8ccd4639055ace3ccbfc 327 Gene3D G3DSA:3.40.50.720 1 265 2.9E-66 T 14-10-2018 TSH58p_08910 c9db81a5178e8ccd4639055ace3ccbfc 327 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 3.4E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_08910 c9db81a5178e8ccd4639055ace3ccbfc 327 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 3.4E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_08910 c9db81a5178e8ccd4639055ace3ccbfc 327 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 3.4E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_08910 c9db81a5178e8ccd4639055ace3ccbfc 327 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.4E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_08910 c9db81a5178e8ccd4639055ace3ccbfc 327 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.4E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_08910 c9db81a5178e8ccd4639055ace3ccbfc 327 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 1.4E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_08910 c9db81a5178e8ccd4639055ace3ccbfc 327 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.4E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_08910 c9db81a5178e8ccd4639055ace3ccbfc 327 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.4E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_08910 c9db81a5178e8ccd4639055ace3ccbfc 327 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.4E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_08910 c9db81a5178e8ccd4639055ace3ccbfc 327 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 0.0043 T 14-10-2018 TSH58p_08910 c9db81a5178e8ccd4639055ace3ccbfc 327 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_08910 c9db81a5178e8ccd4639055ace3ccbfc 327 Pfam PF00106 short chain dehydrogenase 8 193 2.8E-47 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_08910 c9db81a5178e8ccd4639055ace3ccbfc 327 SUPERFAMILY SSF51735 2 239 1.77E-67 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_23495 4ecc6b902a3bca71bfc734c81c0c8751 760 PIRSF PIRSF000379 17 760 0.0 T 14-10-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 TSH58p_23495 4ecc6b902a3bca71bfc734c81c0c8751 760 Pfam PF01228 Glycine radical 635 741 2.0E-43 T 14-10-2018 IPR001150 Glycine radical domain GO:0003824 TSH58p_23495 4ecc6b902a3bca71bfc734c81c0c8751 760 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 21 757 0.0 T 14-10-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 TSH58p_23495 4ecc6b902a3bca71bfc734c81c0c8751 760 Pfam PF02901 Pyruvate formate lyase-like 39 619 3.2E-198 T 14-10-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 TSH58p_23495 4ecc6b902a3bca71bfc734c81c0c8751 760 SUPERFAMILY SSF51998 17 758 6.87E-277 T 14-10-2018 TSH58p_23495 4ecc6b902a3bca71bfc734c81c0c8751 760 Gene3D G3DSA:3.20.70.20 13 759 1.2E-289 T 14-10-2018 TSH58p_23495 4ecc6b902a3bca71bfc734c81c0c8751 760 ProSitePatterns PS00850 Glycine radical domain signature. 730 738 - T 14-10-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site TSH58p_25385 b5a5e853be9404f7671acf26b37d3bfc 399 SUPERFAMILY SSF54826 1 113 9.38E-29 T 14-10-2018 TSH58p_25385 b5a5e853be9404f7671acf26b37d3bfc 399 Pfam PF13378 Enolase C-terminal domain-like 160 384 2.2E-52 T 14-10-2018 IPR029065 Enolase C-terminal domain-like TSH58p_25385 b5a5e853be9404f7671acf26b37d3bfc 399 Gene3D G3DSA:3.20.20.120 106 377 3.0E-90 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TSH58p_25385 b5a5e853be9404f7671acf26b37d3bfc 399 SMART SM00922 155 265 1.4E-13 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal TSH58p_25385 b5a5e853be9404f7671acf26b37d3bfc 399 SUPERFAMILY SSF51604 97 389 6.42E-70 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TSH58p_25385 b5a5e853be9404f7671acf26b37d3bfc 399 Gene3D G3DSA:3.30.390.10 1 105 1.6E-28 T 14-10-2018 IPR029017 Enolase-like, N-terminal TSH58p_25385 b5a5e853be9404f7671acf26b37d3bfc 399 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 13 109 3.8E-19 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain TSH58p_04120 9e188d9b10da4275a38b510ecf064351 157 SUPERFAMILY SSF46785 7 142 1.89E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_04120 9e188d9b10da4275a38b510ecf064351 157 ProSitePatterns PS01117 MarR-type HTH domain signature. 66 100 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site TSH58p_04120 9e188d9b10da4275a38b510ecf064351 157 Pfam PF13463 Winged helix DNA-binding domain 36 100 1.5E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_04120 9e188d9b10da4275a38b510ecf064351 157 Gene3D G3DSA:1.10.10.10 6 141 3.0E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_04120 9e188d9b10da4275a38b510ecf064351 157 SMART SM00347 28 128 3.6E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_09525 c26e0f8467053ab58f2c06c6c3730906 278 SUPERFAMILY SSF54506 4 130 2.45E-41 T 14-10-2018 TSH58p_09525 c26e0f8467053ab58f2c06c6c3730906 278 SUPERFAMILY SSF54506 145 270 2.92E-51 T 14-10-2018 TSH58p_09525 c26e0f8467053ab58f2c06c6c3730906 278 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 4 271 5.5E-84 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 TSH58p_09525 c26e0f8467053ab58f2c06c6c3730906 278 Gene3D G3DSA:3.10.310.10 115 260 1.8E-93 T 14-10-2018 TSH58p_09525 c26e0f8467053ab58f2c06c6c3730906 278 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 273 35.871 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 TSH58p_09525 c26e0f8467053ab58f2c06c6c3730906 278 Gene3D G3DSA:3.10.310.10 4 269 1.8E-93 T 14-10-2018 TSH58p_09525 c26e0f8467053ab58f2c06c6c3730906 278 Pfam PF01678 Diaminopimelate epimerase 152 264 5.0E-32 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 TSH58p_09525 c26e0f8467053ab58f2c06c6c3730906 278 Pfam PF01678 Diaminopimelate epimerase 5 122 3.3E-24 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 TSH58p_09525 c26e0f8467053ab58f2c06c6c3730906 278 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 66 80 - T 14-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 TSH58p_17290 2a5fc8cd9cf69aaa701ed06b375f893f 700 PIRSF PIRSF001265 1 700 1.3E-244 T 14-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 TSH58p_17290 2a5fc8cd9cf69aaa701ed06b375f893f 700 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 6 698 9.0E-267 T 14-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 TSH58p_17290 2a5fc8cd9cf69aaa701ed06b375f893f 700 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 2 697 25.082 T 14-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 TSH58p_17290 2a5fc8cd9cf69aaa701ed06b375f893f 700 Pfam PF03030 Inorganic H+ pyrophosphatase 13 691 9.8E-256 T 14-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 TSH58p_05300 b646f72578f5d4f89ed879e119c5515e 154 Gene3D G3DSA:3.90.1180.10 1 143 2.3E-57 T 14-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 TSH58p_05300 b646f72578f5d4f89ed879e119c5515e 154 Pfam PF00572 Ribosomal protein L13 14 138 3.4E-52 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TSH58p_05300 b646f72578f5d4f89ed879e119c5515e 154 PIRSF PIRSF002181 1 154 1.8E-50 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TSH58p_05300 b646f72578f5d4f89ed879e119c5515e 154 SUPERFAMILY SSF52161 1 140 7.46E-56 T 14-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 TSH58p_05300 b646f72578f5d4f89ed879e119c5515e 154 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 7 142 5.1E-60 T 14-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_05300 b646f72578f5d4f89ed879e119c5515e 154 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 142 28.257 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TSH58p_00980 6f45a522c4f2cda467ad7517bbb7e9bb 400 Gene3D G3DSA:1.25.40.10 6 98 8.0E-15 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_00980 6f45a522c4f2cda467ad7517bbb7e9bb 400 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 283 339 1.5E-6 T 14-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 TSH58p_00980 6f45a522c4f2cda467ad7517bbb7e9bb 400 SUPERFAMILY SSF48452 10 94 1.38E-14 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_00980 6f45a522c4f2cda467ad7517bbb7e9bb 400 SUPERFAMILY SSF53756 132 372 5.34E-18 T 14-10-2018 TSH58p_00980 6f45a522c4f2cda467ad7517bbb7e9bb 400 Gene3D G3DSA:3.40.50.2000 262 359 1.7E-8 T 14-10-2018 TSH58p_31720 0ff83c47162fb0db2b37f989efc48fe7 384 Pfam PF13416 Bacterial extracellular solute-binding protein 51 322 3.0E-24 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSH58p_31720 0ff83c47162fb0db2b37f989efc48fe7 384 Gene3D G3DSA:3.40.190.10 23 384 1.4E-30 T 14-10-2018 TSH58p_31720 0ff83c47162fb0db2b37f989efc48fe7 384 SUPERFAMILY SSF53850 25 335 1.3E-34 T 14-10-2018 TSH58p_20145 b1c6a4264ff1c1468831ebebdcb314ec 58 Pfam PF06796 Periplasmic nitrate reductase protein NapE 8 52 4.0E-16 T 14-10-2018 IPR010649 Nitrate/trimethylamine N-oxide reductase NapE/TorE TSH58p_01035 b84d91929bee573b2d90586cd16832d1 305 Pfam PF03466 LysR substrate binding domain 94 293 1.2E-20 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_01035 b84d91929bee573b2d90586cd16832d1 305 Gene3D G3DSA:1.10.10.10 8 95 1.6E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_01035 b84d91929bee573b2d90586cd16832d1 305 Gene3D G3DSA:3.40.190.10 165 263 2.3E-38 T 14-10-2018 TSH58p_01035 b84d91929bee573b2d90586cd16832d1 305 Gene3D G3DSA:3.40.190.10 103 289 2.3E-38 T 14-10-2018 TSH58p_01035 b84d91929bee573b2d90586cd16832d1 305 SUPERFAMILY SSF53850 95 296 6.33E-23 T 14-10-2018 TSH58p_01035 b84d91929bee573b2d90586cd16832d1 305 SUPERFAMILY SSF46785 3 88 4.52E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_01035 b84d91929bee573b2d90586cd16832d1 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 66 1.3E-15 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_07360 5de02fa81317c7866aafc485b3ea9406 377 Pfam PF03054 tRNA methyl transferase 18 372 8.1E-118 T 14-10-2018 TSH58p_07360 5de02fa81317c7866aafc485b3ea9406 377 Gene3D G3DSA:2.40.30.10 294 375 4.5E-19 T 14-10-2018 TSH58p_07360 5de02fa81317c7866aafc485b3ea9406 377 Gene3D G3DSA:2.30.30.280 230 293 1.5E-18 T 14-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 TSH58p_07360 5de02fa81317c7866aafc485b3ea9406 377 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 17 373 39.989 T 14-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 TSH58p_07360 5de02fa81317c7866aafc485b3ea9406 377 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 18 372 8.6E-101 T 14-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 TSH58p_07360 5de02fa81317c7866aafc485b3ea9406 377 Gene3D G3DSA:3.40.50.620 5 224 3.1E-73 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_07360 5de02fa81317c7866aafc485b3ea9406 377 SUPERFAMILY SSF52402 16 259 9.7E-52 T 14-10-2018 TSH58p_06375 e78dc44518ccdfca90455e1dc44557fe 265 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 12 233 7.3E-108 T 14-10-2018 IPR022488 Polyphosphate kinase-2-related TSH58p_06375 e78dc44518ccdfca90455e1dc44557fe 265 Gene3D G3DSA:3.40.50.300 5 241 1.8E-94 T 14-10-2018 TSH58p_06375 e78dc44518ccdfca90455e1dc44557fe 265 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 12 234 1.1E-113 T 14-10-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 KEGG: 00190+2.7.4.1 TSH58p_06375 e78dc44518ccdfca90455e1dc44557fe 265 PIRSF PIRSF028756 5 265 6.8E-126 T 14-10-2018 IPR016898 Polyphosphate kinase 2 KEGG: 00190+2.7.4.1 TSH58p_06375 e78dc44518ccdfca90455e1dc44557fe 265 SUPERFAMILY SSF52540 41 230 2.09E-33 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_24705 1489911dca6c9ef84df6b34c8a921c33 261 Pfam PF13733 N-terminal region of glycosyl transferase group 7 6 86 5.6E-15 T 14-10-2018 IPR027995 Galactosyltransferase, N-terminal Reactome: R-HSA-2022854|Reactome: R-HSA-975577 TSH58p_24705 1489911dca6c9ef84df6b34c8a921c33 261 Gene3D G3DSA:3.90.550.10 2 244 2.8E-44 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_24705 1489911dca6c9ef84df6b34c8a921c33 261 SUPERFAMILY SSF53448 6 179 1.69E-21 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_24705 1489911dca6c9ef84df6b34c8a921c33 261 Pfam PF02709 N-terminal domain of galactosyltransferase 121 168 1.1E-12 T 14-10-2018 IPR027791 Galactosyltransferase, C-terminal Reactome: R-HSA-2022854|Reactome: R-HSA-975577 TSH58p_24705 1489911dca6c9ef84df6b34c8a921c33 261 PRINTS PR02050 Beta-1,4-galactosyltransferase family signature 140 158 1.7E-15 T 14-10-2018 IPR003859 Beta-1,4-galactosyltransferase GO:0005975|GO:0016757 Reactome: R-HSA-2022854|Reactome: R-HSA-975577 TSH58p_24705 1489911dca6c9ef84df6b34c8a921c33 261 PRINTS PR02050 Beta-1,4-galactosyltransferase family signature 118 139 1.7E-15 T 14-10-2018 IPR003859 Beta-1,4-galactosyltransferase GO:0005975|GO:0016757 Reactome: R-HSA-2022854|Reactome: R-HSA-975577 TSH58p_24705 1489911dca6c9ef84df6b34c8a921c33 261 PRINTS PR02050 Beta-1,4-galactosyltransferase family signature 44 63 1.7E-15 T 14-10-2018 IPR003859 Beta-1,4-galactosyltransferase GO:0005975|GO:0016757 Reactome: R-HSA-2022854|Reactome: R-HSA-975577 TSH58p_24705 1489911dca6c9ef84df6b34c8a921c33 261 PRINTS PR02050 Beta-1,4-galactosyltransferase family signature 73 92 1.7E-15 T 14-10-2018 IPR003859 Beta-1,4-galactosyltransferase GO:0005975|GO:0016757 Reactome: R-HSA-2022854|Reactome: R-HSA-975577 TSH58p_25675 32e522dd34bf75cf1b2fd55f7ff6bf15 347 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 172 184 - T 14-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 TSH58p_25675 32e522dd34bf75cf1b2fd55f7ff6bf15 347 SUPERFAMILY SSF51412 6 336 1.11E-87 T 14-10-2018 TSH58p_25675 32e522dd34bf75cf1b2fd55f7ff6bf15 347 SMART SM01240 7 345 3.2E-97 T 14-10-2018 TSH58p_25675 32e522dd34bf75cf1b2fd55f7ff6bf15 347 Gene3D G3DSA:3.20.20.70 1 346 9.8E-102 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_25675 32e522dd34bf75cf1b2fd55f7ff6bf15 347 Hamap MF_00596 GMP reductase [guaC]. 1 346 46.044 T 14-10-2018 IPR005993 GMP reductase GO:0003920|GO:0009117|GO:1902560 KEGG: 00230+1.7.1.7|Reactome: R-HSA-74217 TSH58p_25675 32e522dd34bf75cf1b2fd55f7ff6bf15 347 TIGRFAM TIGR01305 GMP_reduct_1: guanosine monophosphate reductase 3 345 8.3E-150 T 14-10-2018 IPR005993 GMP reductase GO:0003920|GO:0009117|GO:1902560 KEGG: 00230+1.7.1.7|Reactome: R-HSA-74217 TSH58p_25675 32e522dd34bf75cf1b2fd55f7ff6bf15 347 PIRSF PIRSF000235 1 347 1.1E-164 T 14-10-2018 IPR005993 GMP reductase GO:0003920|GO:0009117|GO:1902560 KEGG: 00230+1.7.1.7|Reactome: R-HSA-74217 TSH58p_25675 32e522dd34bf75cf1b2fd55f7ff6bf15 347 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 9 338 3.7E-68 T 14-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 TSH58p_31900 07dcb6dd77735edb7d0dcb9b4a171bca 256 Pfam PF00106 short chain dehydrogenase 8 196 6.2E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_31900 07dcb6dd77735edb7d0dcb9b4a171bca 256 Gene3D G3DSA:3.40.50.720 1 254 3.1E-64 T 14-10-2018 TSH58p_31900 07dcb6dd77735edb7d0dcb9b4a171bca 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 4.7E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_31900 07dcb6dd77735edb7d0dcb9b4a171bca 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 4.7E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_31900 07dcb6dd77735edb7d0dcb9b4a171bca 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 4.7E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_31900 07dcb6dd77735edb7d0dcb9b4a171bca 256 SUPERFAMILY SSF51735 4 255 8.67E-60 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_31900 07dcb6dd77735edb7d0dcb9b4a171bca 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.5E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_31900 07dcb6dd77735edb7d0dcb9b4a171bca 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.5E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_31900 07dcb6dd77735edb7d0dcb9b4a171bca 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.5E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_31900 07dcb6dd77735edb7d0dcb9b4a171bca 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.5E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_31900 07dcb6dd77735edb7d0dcb9b4a171bca 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.5E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_31900 07dcb6dd77735edb7d0dcb9b4a171bca 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.5E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_08955 94cf8c4cf2ebddf8ccf17b5179463ce3 242 Pfam PF02308 MgtC family 23 155 5.6E-32 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 TSH58p_08955 94cf8c4cf2ebddf8ccf17b5179463ce3 242 PRINTS PR01837 MgtC/SapB protein signature 26 45 7.2E-38 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 TSH58p_08955 94cf8c4cf2ebddf8ccf17b5179463ce3 242 PRINTS PR01837 MgtC/SapB protein signature 45 63 7.2E-38 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 TSH58p_08955 94cf8c4cf2ebddf8ccf17b5179463ce3 242 PRINTS PR01837 MgtC/SapB protein signature 82 104 7.2E-38 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 TSH58p_08955 94cf8c4cf2ebddf8ccf17b5179463ce3 242 PRINTS PR01837 MgtC/SapB protein signature 109 133 7.2E-38 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 TSH58p_13835 d6b9f97c4b9839ff06444d44a17352b5 139 Pfam PF13474 SnoaL-like domain 7 115 1.3E-21 T 14-10-2018 IPR037401 SnoaL-like domain TSH58p_13835 d6b9f97c4b9839ff06444d44a17352b5 139 Gene3D G3DSA:3.10.450.50 1 125 4.1E-41 T 14-10-2018 TSH58p_13835 d6b9f97c4b9839ff06444d44a17352b5 139 SUPERFAMILY SSF54427 1 119 2.64E-33 T 14-10-2018 IPR032710 NTF2-like domain superfamily TSH58p_01860 81fd9a86f5a4ca21398095b9fbe95782 291 Gene3D G3DSA:3.40.190.10 163 257 3.1E-60 T 14-10-2018 TSH58p_01860 81fd9a86f5a4ca21398095b9fbe95782 291 Pfam PF03466 LysR substrate binding domain 93 287 8.1E-39 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_01860 81fd9a86f5a4ca21398095b9fbe95782 291 Gene3D G3DSA:1.10.10.10 6 94 2.0E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_01860 81fd9a86f5a4ca21398095b9fbe95782 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 2.9E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_01860 81fd9a86f5a4ca21398095b9fbe95782 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 2.9E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_01860 81fd9a86f5a4ca21398095b9fbe95782 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 2.9E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_01860 81fd9a86f5a4ca21398095b9fbe95782 291 Gene3D G3DSA:3.40.190.10 103 283 3.1E-60 T 14-10-2018 TSH58p_01860 81fd9a86f5a4ca21398095b9fbe95782 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 3.3E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_01860 81fd9a86f5a4ca21398095b9fbe95782 291 SUPERFAMILY SSF53850 94 288 2.35E-35 T 14-10-2018 TSH58p_01860 81fd9a86f5a4ca21398095b9fbe95782 291 SUPERFAMILY SSF46785 4 86 4.66E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_03165 c7cb64a1292731774c219e7a72e53523 651 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 460 489 2.5E-23 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_03165 c7cb64a1292731774c219e7a72e53523 651 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 412 441 2.5E-23 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_03165 c7cb64a1292731774c219e7a72e53523 651 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 383 410 2.5E-23 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_03165 c7cb64a1292731774c219e7a72e53523 651 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 306 335 2.5E-23 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_03165 c7cb64a1292731774c219e7a72e53523 651 Gene3D G3DSA:1.10.287.950 252 548 3.5E-53 T 14-10-2018 TSH58p_03165 c7cb64a1292731774c219e7a72e53523 651 SUPERFAMILY SSF141371 544 622 1.73E-5 T 14-10-2018 TSH58p_03165 c7cb64a1292731774c219e7a72e53523 651 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 362 507 1.5E-31 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_03165 c7cb64a1292731774c219e7a72e53523 651 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 7 92 3.6E-11 T 14-10-2018 IPR000014 PAS domain TSH58p_03165 c7cb64a1292731774c219e7a72e53523 651 SUPERFAMILY SSF55785 4 97 5.06E-24 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_03165 c7cb64a1292731774c219e7a72e53523 651 SMART SM00283 285 539 3.0E-44 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_03165 c7cb64a1292731774c219e7a72e53523 651 Pfam PF07238 PilZ domain 547 629 4.3E-8 T 14-10-2018 IPR009875 PilZ domain GO:0035438 TSH58p_03165 c7cb64a1292731774c219e7a72e53523 651 Pfam PF08447 PAS fold 14 97 3.3E-14 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 TSH58p_03165 c7cb64a1292731774c219e7a72e53523 651 SUPERFAMILY SSF58104 291 533 4.71E-54 T 14-10-2018 TSH58p_03165 c7cb64a1292731774c219e7a72e53523 651 Gene3D G3DSA:3.30.450.20 2 124 1.4E-24 T 14-10-2018 TSH58p_18595 3535acd15b0bb3c86ebe58d4ff078bbd 253 Pfam PF01925 Sulfite exporter TauE/SafE 15 238 1.3E-13 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TSH58p_13460 7e69a3a2dd864492f11656c04923f6a1 362 SUPERFAMILY SSF161098 134 321 5.49E-20 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_13460 7e69a3a2dd864492f11656c04923f6a1 362 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 157 339 2.1E-29 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_13460 7e69a3a2dd864492f11656c04923f6a1 362 Gene3D G3DSA:1.10.3720.10 128 339 6.0E-17 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_21780 214a09b90b96c6c273b42ded822b8081 433 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 21 428 7.4E-112 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSH58p_21780 214a09b90b96c6c273b42ded822b8081 433 PIRSF PIRSF006066 5 433 4.3E-91 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSH58p_21780 214a09b90b96c6c273b42ded822b8081 433 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 11 423 1.2E-85 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TSH58p_00880 eb0798f6597dc5f16144b57c9592b652 682 SUPERFAMILY SSF50182 487 550 6.54E-11 T 14-10-2018 IPR010920 LSM domain superfamily TSH58p_00880 eb0798f6597dc5f16144b57c9592b652 682 Pfam PF00924 Mechanosensitive ion channel 444 643 5.3E-39 T 14-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 TSH58p_00880 eb0798f6597dc5f16144b57c9592b652 682 SUPERFAMILY SSF82689 550 643 8.11E-9 T 14-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 TSH58p_00880 eb0798f6597dc5f16144b57c9592b652 682 Gene3D G3DSA:2.30.30.60 502 551 5.5E-15 T 14-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily TSH58p_00880 eb0798f6597dc5f16144b57c9592b652 682 Gene3D G3DSA:3.30.70.100 555 642 2.4E-16 T 14-10-2018 TSH58p_00880 eb0798f6597dc5f16144b57c9592b652 682 SUPERFAMILY SSF82861 398 485 8.76E-15 T 14-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 TSH58p_26940 cb3b2b191a2840d01844516d33d562e1 260 Gene3D G3DSA:3.90.70.30 43 251 7.6E-40 T 14-10-2018 IPR038156 Phytochelatin synthase, N-terminal domain superfamily MetaCyc: PWY-6745 TSH58p_26940 cb3b2b191a2840d01844516d33d562e1 260 Pfam PF05023 Phytochelatin synthase 50 239 7.9E-27 T 14-10-2018 IPR007719 Phytochelatin synthase, N-terminal catalytic domain GO:0010038|GO:0016756|GO:0046872|GO:0046938 MetaCyc: PWY-6745 TSH58p_26940 cb3b2b191a2840d01844516d33d562e1 260 SUPERFAMILY SSF54001 55 247 2.35E-28 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily TSH58p_03095 2a1aa3b638eec7fb65576a5fc01726f4 246 Gene3D G3DSA:3.40.50.720 1 245 2.7E-83 T 14-10-2018 TSH58p_03095 2a1aa3b638eec7fb65576a5fc01726f4 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 5.4E-49 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03095 2a1aa3b638eec7fb65576a5fc01726f4 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 5.4E-49 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03095 2a1aa3b638eec7fb65576a5fc01726f4 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 5.4E-49 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03095 2a1aa3b638eec7fb65576a5fc01726f4 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 5.4E-49 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03095 2a1aa3b638eec7fb65576a5fc01726f4 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 5.4E-49 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03095 2a1aa3b638eec7fb65576a5fc01726f4 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 5.4E-49 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03095 2a1aa3b638eec7fb65576a5fc01726f4 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 184 1.5E-4 T 14-10-2018 TSH58p_03095 2a1aa3b638eec7fb65576a5fc01726f4 246 Pfam PF00106 short chain dehydrogenase 4 197 2.8E-66 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03095 2a1aa3b638eec7fb65576a5fc01726f4 246 SUPERFAMILY SSF51735 3 244 1.02E-82 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_03095 2a1aa3b638eec7fb65576a5fc01726f4 246 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 4 244 7.6E-124 T 14-10-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216|MetaCyc: PWY-7948 TSH58p_03095 2a1aa3b638eec7fb65576a5fc01726f4 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 2.1E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03095 2a1aa3b638eec7fb65576a5fc01726f4 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.1E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03095 2a1aa3b638eec7fb65576a5fc01726f4 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.1E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_03095 2a1aa3b638eec7fb65576a5fc01726f4 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_18655 dd615f8ce7c8ec3ef30ec56169153dcc 359 SUPERFAMILY SSF51569 3 355 9.52E-104 T 14-10-2018 TSH58p_18655 dd615f8ce7c8ec3ef30ec56169153dcc 359 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 13 355 5.1E-88 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 TSH58p_18655 dd615f8ce7c8ec3ef30ec56169153dcc 359 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 169 180 - T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 TSH58p_18655 dd615f8ce7c8ec3ef30ec56169153dcc 359 Gene3D G3DSA:3.20.20.70 1 356 7.6E-114 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_18655 dd615f8ce7c8ec3ef30ec56169153dcc 359 PIRSF PIRSF001359 12 356 8.1E-72 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 TSH58p_18655 dd615f8ce7c8ec3ef30ec56169153dcc 359 Pfam PF01116 Fructose-bisphosphate aldolase class-II 16 355 1.6E-79 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 TSH58p_18655 dd615f8ce7c8ec3ef30ec56169153dcc 359 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 6 355 7.5E-135 T 14-10-2018 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TSH58p_14635 0e3273e49b9c1c59b44aa42432670498 149 Pfam PF01220 Dehydroquinase class II 7 142 1.5E-60 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TSH58p_14635 0e3273e49b9c1c59b44aa42432670498 149 PIRSF PIRSF001399 3 149 5.2E-65 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TSH58p_14635 0e3273e49b9c1c59b44aa42432670498 149 SUPERFAMILY SSF52304 6 147 2.35E-62 T 14-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TSH58p_14635 0e3273e49b9c1c59b44aa42432670498 149 Gene3D G3DSA:3.40.50.9100 1 149 6.8E-66 T 14-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TSH58p_14635 0e3273e49b9c1c59b44aa42432670498 149 ProSitePatterns PS01029 Dehydroquinase class II signature. 10 27 - T 14-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TSH58p_14635 0e3273e49b9c1c59b44aa42432670498 149 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 7 145 4.5E-61 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TSH58p_14635 0e3273e49b9c1c59b44aa42432670498 149 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 149 69.285 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TSH58p_14635 0e3273e49b9c1c59b44aa42432670498 149 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 7 143 3.0E-48 T 14-10-2018 TSH58p_23525 25d8c52323bb84d5d08dc10abdd4d47e 772 Pfam PF01515 Phosphate acetyl/butaryl transferase 429 749 5.8E-94 T 14-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 TSH58p_23525 25d8c52323bb84d5d08dc10abdd4d47e 772 Pfam PF00390 Malic enzyme, N-terminal domain 20 150 3.8E-25 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 TSH58p_23525 25d8c52323bb84d5d08dc10abdd4d47e 772 SUPERFAMILY SSF51735 163 442 2.3E-82 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_23525 25d8c52323bb84d5d08dc10abdd4d47e 772 Gene3D G3DSA:3.40.50.10950 445 749 4.7E-92 T 14-10-2018 TSH58p_23525 25d8c52323bb84d5d08dc10abdd4d47e 772 Pfam PF03949 Malic enzyme, NAD binding domain 165 357 3.5E-19 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 TSH58p_23525 25d8c52323bb84d5d08dc10abdd4d47e 772 Gene3D G3DSA:3.40.50.10380 1 160 2.6E-65 T 14-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 TSH58p_23525 25d8c52323bb84d5d08dc10abdd4d47e 772 SMART SM00919 163 400 1.6E-131 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 TSH58p_23525 25d8c52323bb84d5d08dc10abdd4d47e 772 SUPERFAMILY SSF53659 429 752 7.4E-89 T 14-10-2018 TSH58p_23525 25d8c52323bb84d5d08dc10abdd4d47e 772 SUPERFAMILY SSF53223 11 161 2.88E-50 T 14-10-2018 TSH58p_23525 25d8c52323bb84d5d08dc10abdd4d47e 772 Gene3D G3DSA:3.40.50.10750 572 725 4.7E-92 T 14-10-2018 TSH58p_23525 25d8c52323bb84d5d08dc10abdd4d47e 772 PIRSF PIRSF036684 1 756 0.0 T 14-10-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 TSH58p_23525 25d8c52323bb84d5d08dc10abdd4d47e 772 Gene3D G3DSA:3.40.50.720 161 444 1.5E-79 T 14-10-2018 TSH58p_23525 25d8c52323bb84d5d08dc10abdd4d47e 772 SMART SM01274 18 151 2.1E-73 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 TSH58p_13380 46754ce332b8f355df6f54b53a25cba9 241 Pfam PF03942 DTW domain 4 202 1.8E-36 T 14-10-2018 IPR005636 DTW TSH58p_13380 46754ce332b8f355df6f54b53a25cba9 241 SMART SM01144 2 208 2.2E-42 T 14-10-2018 IPR005636 DTW TSH58p_15525 fb5b7c9aad98d27c5fe6e79599425a3f 359 Pfam PF00154 recA bacterial DNA recombination protein 18 280 2.2E-146 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TSH58p_15525 fb5b7c9aad98d27c5fe6e79599425a3f 359 SMART SM00382 69 240 6.9E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_15525 fb5b7c9aad98d27c5fe6e79599425a3f 359 Hamap MF_00268 Protein RecA [recA]. 16 341 52.098 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TSH58p_15525 fb5b7c9aad98d27c5fe6e79599425a3f 359 PRINTS PR00142 RecA protein signature 139 168 1.6E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TSH58p_15525 fb5b7c9aad98d27c5fe6e79599425a3f 359 PRINTS PR00142 RecA protein signature 177 206 1.6E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TSH58p_15525 fb5b7c9aad98d27c5fe6e79599425a3f 359 PRINTS PR00142 RecA protein signature 105 134 1.6E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TSH58p_15525 fb5b7c9aad98d27c5fe6e79599425a3f 359 PRINTS PR00142 RecA protein signature 222 250 1.6E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TSH58p_15525 fb5b7c9aad98d27c5fe6e79599425a3f 359 PRINTS PR00142 RecA protein signature 255 284 1.6E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TSH58p_15525 fb5b7c9aad98d27c5fe6e79599425a3f 359 PRINTS PR00142 RecA protein signature 309 326 1.6E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TSH58p_15525 fb5b7c9aad98d27c5fe6e79599425a3f 359 Gene3D G3DSA:3.40.50.300 40 279 3.5E-83 T 14-10-2018 TSH58p_15525 fb5b7c9aad98d27c5fe6e79599425a3f 359 SUPERFAMILY SSF54752 280 337 6.15E-21 T 14-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal TSH58p_15525 fb5b7c9aad98d27c5fe6e79599425a3f 359 Gene3D G3DSA:3.30.250.10 280 356 1.4E-25 T 14-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal TSH58p_15525 fb5b7c9aad98d27c5fe6e79599425a3f 359 ProSitePatterns PS00321 recA signature. 225 233 - T 14-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 TSH58p_15525 fb5b7c9aad98d27c5fe6e79599425a3f 359 SUPERFAMILY SSF52540 16 279 1.49E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_15525 fb5b7c9aad98d27c5fe6e79599425a3f 359 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 15 335 8.9E-173 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TSH58p_05135 19837c322093814b0b1b4c68fd33ae99 613 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 135 583 9.5E-214 T 14-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 TSH58p_05135 19837c322093814b0b1b4c68fd33ae99 613 Pfam PF13667 ThiC-associated domain 24 94 6.3E-24 T 14-10-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 TSH58p_05135 19837c322093814b0b1b4c68fd33ae99 613 Pfam PF01964 Radical SAM ThiC family 136 581 9.5E-200 T 14-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 TSH58p_05135 19837c322093814b0b1b4c68fd33ae99 613 Gene3D G3DSA:3.20.20.540 203 516 2.1E-153 T 14-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 TSH58p_05135 19837c322093814b0b1b4c68fd33ae99 613 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 135 585 99.379 T 14-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 TSH58p_28015 25f4999ad829408e4e63b3e5cf564b72 76 Pfam PF01455 HupF/HypC family 1 66 6.4E-25 T 14-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TSH58p_28015 25f4999ad829408e4e63b3e5cf564b72 76 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 69 1.3E-20 T 14-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TSH58p_28015 25f4999ad829408e4e63b3e5cf564b72 76 Gene3D G3DSA:2.40.50.970 1 73 5.9E-26 T 14-10-2018 IPR037254 HupF/HypC superfamily TSH58p_28015 25f4999ad829408e4e63b3e5cf564b72 76 SUPERFAMILY SSF159127 1 71 2.49E-22 T 14-10-2018 IPR037254 HupF/HypC superfamily TSH58p_28015 25f4999ad829408e4e63b3e5cf564b72 76 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 14-10-2018 IPR019812 Hydrogenase assembly chaperone, conserved site TSH58p_28015 25f4999ad829408e4e63b3e5cf564b72 76 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 18 34 9.9E-18 T 14-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TSH58p_28015 25f4999ad829408e4e63b3e5cf564b72 76 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 57 69 9.9E-18 T 14-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TSH58p_28015 25f4999ad829408e4e63b3e5cf564b72 76 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 39 55 9.9E-18 T 14-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TSH58p_28015 25f4999ad829408e4e63b3e5cf564b72 76 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 9.9E-18 T 14-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TSH58p_21870 e7fc96426dc0974c815fedaa50a9d787 287 SUPERFAMILY SSF52172 29 184 6.69E-32 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_21870 e7fc96426dc0974c815fedaa50a9d787 287 SUPERFAMILY SSF46894 161 262 1.08E-14 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_21870 e7fc96426dc0974c815fedaa50a9d787 287 SMART SM00448 28 140 4.5E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_21870 e7fc96426dc0974c815fedaa50a9d787 287 Gene3D G3DSA:1.10.10.10 156 264 3.9E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_21870 e7fc96426dc0974c815fedaa50a9d787 287 SMART SM00862 180 262 6.7E-11 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_21870 e7fc96426dc0974c815fedaa50a9d787 287 Gene3D G3DSA:3.40.50.2300 26 155 7.2E-30 T 14-10-2018 TSH58p_21870 e7fc96426dc0974c815fedaa50a9d787 287 Pfam PF00486 Transcriptional regulatory protein, C terminal 180 261 2.4E-9 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_21870 e7fc96426dc0974c815fedaa50a9d787 287 Pfam PF00072 Response regulator receiver domain 30 139 2.8E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_09720 86c33271410b11169dc0835fcf72cddb 201 SUPERFAMILY SSF47616 81 198 1.81E-32 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily TSH58p_09720 86c33271410b11169dc0835fcf72cddb 201 Gene3D G3DSA:1.20.1050.10 83 188 2.6E-71 T 14-10-2018 TSH58p_09720 86c33271410b11169dc0835fcf72cddb 201 Gene3D G3DSA:3.40.30.10 3 191 2.6E-71 T 14-10-2018 TSH58p_09720 86c33271410b11169dc0835fcf72cddb 201 Pfam PF02798 Glutathione S-transferase, N-terminal domain 1 74 4.1E-10 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 TSH58p_09720 86c33271410b11169dc0835fcf72cddb 201 SUPERFAMILY SSF52833 1 85 2.57E-18 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_09720 86c33271410b11169dc0835fcf72cddb 201 Pfam PF00043 Glutathione S-transferase, C-terminal domain 104 189 1.4E-15 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal TSH58p_05895 24769d14545c8e8edd35d5398f6cf337 205 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 26 171 2.8E-63 T 14-10-2018 TSH58p_05895 24769d14545c8e8edd35d5398f6cf337 205 Gene3D G3DSA:3.40.30.10 90 191 4.3E-34 T 14-10-2018 TSH58p_05895 24769d14545c8e8edd35d5398f6cf337 205 SUPERFAMILY SSF52833 17 190 2.98E-60 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_05895 24769d14545c8e8edd35d5398f6cf337 205 Gene3D G3DSA:1.10.10.1590 15 89 7.7E-28 T 14-10-2018 TSH58p_05895 24769d14545c8e8edd35d5398f6cf337 205 PIRSF PIRSF000216 1 205 6.4E-78 T 14-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05895 24769d14545c8e8edd35d5398f6cf337 205 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 26 172 6.3E-59 T 14-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_23615 2b0058f6e9d8ed8e560393667a2d712b 259 Pfam PF00005 ABC transporter 31 185 3.6E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_23615 2b0058f6e9d8ed8e560393667a2d712b 259 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 233 255 1.5E-7 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSH58p_23615 2b0058f6e9d8ed8e560393667a2d712b 259 SUPERFAMILY SSF52540 13 255 5.98E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_23615 2b0058f6e9d8ed8e560393667a2d712b 259 SMART SM00382 39 233 3.6E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_23615 2b0058f6e9d8ed8e560393667a2d712b 259 Gene3D G3DSA:3.40.50.300 12 257 1.2E-55 T 14-10-2018 TSH58p_09375 3f6618cea1632119391016aad4489bab 307 Gene3D G3DSA:3.40.50.880 1 300 1.1E-119 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_09375 3f6618cea1632119391016aad4489bab 307 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 36 292 5.0E-105 T 14-10-2018 TSH58p_09375 3f6618cea1632119391016aad4489bab 307 TIGRFAM TIGR01001 metA: homoserine O-succinyltransferase 1 300 3.3E-105 T 14-10-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 TSH58p_09375 3f6618cea1632119391016aad4489bab 307 Pfam PF04204 Homoserine O-succinyltransferase 2 298 5.2E-124 T 14-10-2018 IPR033752 MetA family TSH58p_09375 3f6618cea1632119391016aad4489bab 307 PIRSF PIRSF000450 1 307 3.1E-131 T 14-10-2018 IPR033752 MetA family TSH58p_09375 3f6618cea1632119391016aad4489bab 307 Hamap MF_00295 Homoserine O-succinyltransferase [metAS]. 31 298 39.804 T 14-10-2018 IPR033752 MetA family TSH58p_09375 3f6618cea1632119391016aad4489bab 307 SUPERFAMILY SSF52317 18 296 5.38E-96 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_13935 fdae36d05e644839b095c0d75e589b33 131 SUPERFAMILY SSF51182 6 130 4.89E-31 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_13935 fdae36d05e644839b095c0d75e589b33 131 Gene3D G3DSA:2.60.120.10 1 130 1.6E-53 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_13935 fdae36d05e644839b095c0d75e589b33 131 Pfam PF07883 Cupin domain 42 97 1.8E-12 T 14-10-2018 IPR013096 Cupin 2, conserved barrel TSH58p_01790 34b94822a88353094821297980beefe9 392 Gene3D G3DSA:3.90.1150.10 28 381 1.3E-120 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_01790 34b94822a88353094821297980beefe9 392 SUPERFAMILY SSF53383 17 385 2.26E-113 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_01790 34b94822a88353094821297980beefe9 392 Gene3D G3DSA:3.40.640.10 64 283 1.3E-120 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_01790 34b94822a88353094821297980beefe9 392 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 233 246 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TSH58p_01790 34b94822a88353094821297980beefe9 392 Pfam PF00155 Aminotransferase class I and II 33 381 2.9E-65 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSH58p_24205 d9a74e74c6dc8c5437371cde15250eed 424 SUPERFAMILY SSF53822 49 387 1.52E-58 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_24205 d9a74e74c6dc8c5437371cde15250eed 424 Gene3D G3DSA:3.40.50.2300 50 368 6.6E-60 T 14-10-2018 TSH58p_24205 d9a74e74c6dc8c5437371cde15250eed 424 Gene3D G3DSA:3.40.50.2300 163 301 6.6E-60 T 14-10-2018 TSH58p_24205 d9a74e74c6dc8c5437371cde15250eed 424 Pfam PF13458 Periplasmic binding protein 49 387 6.3E-43 T 14-10-2018 IPR028081 Leucine-binding protein domain TSH58p_24540 ae32ea330323a5d17635df7286ce4a32 154 Pfam PF12802 MarR family 50 99 2.1E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_24540 ae32ea330323a5d17635df7286ce4a32 154 SMART SM00347 34 135 1.4E-20 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_24540 ae32ea330323a5d17635df7286ce4a32 154 SUPERFAMILY SSF46785 8 148 3.58E-32 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_24540 ae32ea330323a5d17635df7286ce4a32 154 Gene3D G3DSA:1.10.10.10 15 153 6.3E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_24540 ae32ea330323a5d17635df7286ce4a32 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 59 75 2.9E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_24540 ae32ea330323a5d17635df7286ce4a32 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 111 2.9E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_24540 ae32ea330323a5d17635df7286ce4a32 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 91 2.9E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_02780 3b8f15185509ad08d16c885e4d270d8d 332 Pfam PF03466 LysR substrate binding domain 99 306 7.8E-28 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_02780 3b8f15185509ad08d16c885e4d270d8d 332 SUPERFAMILY SSF46785 13 99 5.52E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_02780 3b8f15185509ad08d16c885e4d270d8d 332 Gene3D G3DSA:3.40.190.10 173 280 9.7E-22 T 14-10-2018 TSH58p_02780 3b8f15185509ad08d16c885e4d270d8d 332 Gene3D G3DSA:3.40.190.10 103 303 9.7E-22 T 14-10-2018 TSH58p_02780 3b8f15185509ad08d16c885e4d270d8d 332 SUPERFAMILY SSF53850 100 312 7.76E-31 T 14-10-2018 TSH58p_02780 3b8f15185509ad08d16c885e4d270d8d 332 Gene3D G3DSA:1.10.10.10 9 87 6.6E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_02780 3b8f15185509ad08d16c885e4d270d8d 332 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 74 8.9E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_02780 3b8f15185509ad08d16c885e4d270d8d 332 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 41 1.1E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_02780 3b8f15185509ad08d16c885e4d270d8d 332 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 51 1.1E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_02780 3b8f15185509ad08d16c885e4d270d8d 332 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 51 62 1.1E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_03505 34c7f708aff49f349d9f05aec3c42df8 86 Gene3D G3DSA:1.10.10.10 31 85 1.1E-5 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_17665 34c7f708aff49f349d9f05aec3c42df8 86 Gene3D G3DSA:1.10.10.10 31 85 1.1E-5 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_17740 34c7f708aff49f349d9f05aec3c42df8 86 Gene3D G3DSA:1.10.10.10 31 85 1.1E-5 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_18145 72b0d85b171c1e0e22d5030ea6bf89f7 359 Gene3D G3DSA:3.40.50.720 9 337 1.0E-58 T 14-10-2018 TSH58p_18145 72b0d85b171c1e0e22d5030ea6bf89f7 359 Gene3D G3DSA:3.90.25.10 217 350 1.0E-58 T 14-10-2018 TSH58p_18145 72b0d85b171c1e0e22d5030ea6bf89f7 359 SUPERFAMILY SSF51735 8 348 1.94E-54 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_18145 72b0d85b171c1e0e22d5030ea6bf89f7 359 Pfam PF01370 NAD dependent epimerase/dehydratase family 9 277 1.1E-33 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TSH58p_14110 720ca35b99ac92befa3b3d0d04bd8f54 187 SUPERFAMILY SSF55729 6 168 1.36E-31 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_14110 720ca35b99ac92befa3b3d0d04bd8f54 187 Gene3D G3DSA:3.40.630.30 1 179 4.6E-50 T 14-10-2018 TSH58p_14110 720ca35b99ac92befa3b3d0d04bd8f54 187 Pfam PF13420 Acetyltransferase (GNAT) domain 7 161 8.1E-24 T 14-10-2018 TSH58p_03230 b5226acccb0ac63b314b7d5b3754b041 273 Pfam PF04391 Protein of unknown function (DUF533) 105 272 4.3E-42 T 14-10-2018 IPR007486 Inner membrane protein YebE TSH58p_03230 b5226acccb0ac63b314b7d5b3754b041 273 Gene3D G3DSA:1.10.3680.10 157 273 1.2E-10 T 14-10-2018 IPR029024 TerB-like TSH58p_03230 b5226acccb0ac63b314b7d5b3754b041 273 SUPERFAMILY SSF158682 57 271 1.24E-17 T 14-10-2018 IPR029024 TerB-like TSH58p_02335 7f39cdcefcfc19e817ae2bf20dc112d9 124 SUPERFAMILY SSF52172 9 122 2.56E-29 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_02335 7f39cdcefcfc19e817ae2bf20dc112d9 124 SMART SM00448 7 118 4.9E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_02335 7f39cdcefcfc19e817ae2bf20dc112d9 124 Pfam PF00072 Response regulator receiver domain 9 119 1.3E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_02335 7f39cdcefcfc19e817ae2bf20dc112d9 124 Gene3D G3DSA:3.40.50.2300 4 124 3.7E-35 T 14-10-2018 TSH58p_13700 68efe7dd12601f55c85a0b6e368eb879 521 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 9 511 2.2E-206 T 14-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_13700 68efe7dd12601f55c85a0b6e368eb879 521 Gene3D G3DSA:3.40.1450.10 81 311 8.6E-205 T 14-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_13700 68efe7dd12601f55c85a0b6e368eb879 521 SUPERFAMILY SSF64158 81 300 1.06E-75 T 14-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_13700 68efe7dd12601f55c85a0b6e368eb879 521 SUPERFAMILY SSF53649 8 511 7.85E-75 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 TSH58p_13700 68efe7dd12601f55c85a0b6e368eb879 521 PIRSF PIRSF001492 2 514 1.6E-198 T 14-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_13700 68efe7dd12601f55c85a0b6e368eb879 521 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 8 512 47.653 T 14-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_13700 68efe7dd12601f55c85a0b6e368eb879 521 Gene3D G3DSA:3.40.720.10 9 511 8.6E-205 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 TSH58p_13700 68efe7dd12601f55c85a0b6e368eb879 521 Pfam PF01676 Metalloenzyme superfamily 9 500 3.9E-73 T 14-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 TSH58p_13700 68efe7dd12601f55c85a0b6e368eb879 521 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 86 296 9.7E-72 T 14-10-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSH58p_14735 9eaabbcc8fe7c58316933e8996b9cddc 149 Pfam PF07681 DoxX 17 95 1.5E-16 T 14-10-2018 IPR032808 DoxX family TSH58p_13180 75d38d26dd127de5d2fd835d608ad571 467 PRINTS PR00415 Aconitase family signature 135 150 8.3E-51 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_13180 75d38d26dd127de5d2fd835d608ad571 467 PRINTS PR00415 Aconitase family signature 211 224 8.3E-51 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_13180 75d38d26dd127de5d2fd835d608ad571 467 PRINTS PR00415 Aconitase family signature 121 134 8.3E-51 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_13180 75d38d26dd127de5d2fd835d608ad571 467 PRINTS PR00415 Aconitase family signature 110 118 8.3E-51 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_13180 75d38d26dd127de5d2fd835d608ad571 467 PRINTS PR00415 Aconitase family signature 288 302 8.3E-51 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_13180 75d38d26dd127de5d2fd835d608ad571 467 PRINTS PR00415 Aconitase family signature 345 356 8.3E-51 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_13180 75d38d26dd127de5d2fd835d608ad571 467 PRINTS PR00415 Aconitase family signature 197 210 8.3E-51 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_13180 75d38d26dd127de5d2fd835d608ad571 467 PRINTS PR00415 Aconitase family signature 401 414 8.3E-51 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_13180 75d38d26dd127de5d2fd835d608ad571 467 PRINTS PR00415 Aconitase family signature 84 97 8.3E-51 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_13180 75d38d26dd127de5d2fd835d608ad571 467 ProSitePatterns PS01244 Aconitase family signature 2. 401 414 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 TSH58p_13180 75d38d26dd127de5d2fd835d608ad571 467 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 3 467 60.827 T 14-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 TSH58p_13180 75d38d26dd127de5d2fd835d608ad571 467 Pfam PF00330 Aconitase family (aconitate hydratase) 9 459 8.1E-162 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSH58p_13180 75d38d26dd127de5d2fd835d608ad571 467 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 4 466 4.3E-248 T 14-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 TSH58p_13180 75d38d26dd127de5d2fd835d608ad571 467 SUPERFAMILY SSF53732 3 466 1.44E-168 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 TSH58p_13180 75d38d26dd127de5d2fd835d608ad571 467 Gene3D G3DSA:3.30.499.20 6 288 9.0E-102 T 14-10-2018 TSH58p_13180 75d38d26dd127de5d2fd835d608ad571 467 ProSitePatterns PS00450 Aconitase family signature 1. 341 357 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 TSH58p_13180 75d38d26dd127de5d2fd835d608ad571 467 Gene3D G3DSA:3.30.499.10 329 467 3.2E-51 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 TSH58p_28935 08634bd3ff0a310bd5c1fc3caeb6e1cc 558 SMART SM00283 294 552 1.3E-38 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_28935 08634bd3ff0a310bd5c1fc3caeb6e1cc 558 SUPERFAMILY SSF58104 237 551 6.41E-61 T 14-10-2018 TSH58p_28935 08634bd3ff0a310bd5c1fc3caeb6e1cc 558 Gene3D G3DSA:1.10.287.950 268 557 3.6E-54 T 14-10-2018 TSH58p_28935 08634bd3ff0a310bd5c1fc3caeb6e1cc 558 SMART SM00304 208 261 2.7E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_28935 08634bd3ff0a310bd5c1fc3caeb6e1cc 558 Gene3D G3DSA:1.20.1480.50 169 267 2.8E-16 T 14-10-2018 TSH58p_28935 08634bd3ff0a310bd5c1fc3caeb6e1cc 558 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 371 523 2.1E-33 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_28935 08634bd3ff0a310bd5c1fc3caeb6e1cc 558 Pfam PF00672 HAMP domain 208 258 3.5E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_28935 08634bd3ff0a310bd5c1fc3caeb6e1cc 558 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 315 344 8.7E-19 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_28935 08634bd3ff0a310bd5c1fc3caeb6e1cc 558 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 425 454 8.7E-19 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_28935 08634bd3ff0a310bd5c1fc3caeb6e1cc 558 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 396 423 8.7E-19 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_22030 c2532a6f841458b59014a8be2e7bd7f2 310 Gene3D G3DSA:1.10.10.10 1 85 7.1E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_22030 c2532a6f841458b59014a8be2e7bd7f2 310 Pfam PF03466 LysR substrate binding domain 86 288 8.8E-35 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_22030 c2532a6f841458b59014a8be2e7bd7f2 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 49 8.0E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_22030 c2532a6f841458b59014a8be2e7bd7f2 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 17 28 8.0E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_22030 c2532a6f841458b59014a8be2e7bd7f2 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 38 8.0E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_22030 c2532a6f841458b59014a8be2e7bd7f2 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 2 60 1.9E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_22030 c2532a6f841458b59014a8be2e7bd7f2 310 SUPERFAMILY SSF53850 86 290 5.43E-35 T 14-10-2018 TSH58p_22030 c2532a6f841458b59014a8be2e7bd7f2 310 SUPERFAMILY SSF46785 3 102 1.96E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_22030 c2532a6f841458b59014a8be2e7bd7f2 310 Gene3D G3DSA:3.40.190.290 90 294 4.2E-37 T 14-10-2018 TSH58p_09780 a2543379f4c051880bb9e6ac48c30697 228 Gene3D G3DSA:3.40.50.1000 4 207 4.9E-81 T 14-10-2018 IPR023214 HAD superfamily TSH58p_09780 a2543379f4c051880bb9e6ac48c30697 228 Gene3D G3DSA:1.10.150.240 17 98 4.9E-81 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 TSH58p_09780 a2543379f4c051880bb9e6ac48c30697 228 SUPERFAMILY SSF56784 1 225 8.55E-34 T 14-10-2018 IPR036412 HAD-like superfamily TSH58p_09780 a2543379f4c051880bb9e6ac48c30697 228 Pfam PF13419 Haloacid dehalogenase-like hydrolase 34 182 2.9E-8 T 14-10-2018 TSH58p_19400 3ad5d6c0f7e1fdd38262e28145c5ecd5 399 Gene3D G3DSA:1.10.10.660 35 102 2.9E-48 T 14-10-2018 IPR024033 Uncharacterised domain superfamily, YlbE TSH58p_19400 3ad5d6c0f7e1fdd38262e28145c5ecd5 399 Gene3D G3DSA:3.90.1700.10 234 387 3.2E-31 T 14-10-2018 TSH58p_19400 3ad5d6c0f7e1fdd38262e28145c5ecd5 399 Pfam PF06545 Protein of unknown function (DUF1116) 82 285 1.9E-58 T 14-10-2018 IPR009499 Protein of unknown function DUF1116 TSH58p_19400 3ad5d6c0f7e1fdd38262e28145c5ecd5 399 Gene3D G3DSA:3.90.1710.10 103 226 2.9E-48 T 14-10-2018 TSH58p_02140 564204c88449b7da468abcf01d26038e 428 Gene3D G3DSA:1.20.1250.20 2 196 4.1E-43 T 14-10-2018 TSH58p_02140 564204c88449b7da468abcf01d26038e 428 PIRSF PIRSF002808 2 419 1.2E-35 T 14-10-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 TSH58p_02140 564204c88449b7da468abcf01d26038e 428 Pfam PF07690 Major Facilitator Superfamily 15 331 3.0E-46 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_02140 564204c88449b7da468abcf01d26038e 428 SUPERFAMILY SSF103473 3 408 3.92E-77 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_02140 564204c88449b7da468abcf01d26038e 428 Gene3D G3DSA:1.20.1250.20 213 411 3.7E-28 T 14-10-2018 TSH58p_10055 d75554aba2c3e85f7ac75505dcd3349c 237 Pfam PF07722 Peptidase C26 50 206 1.4E-43 T 14-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 TSH58p_10055 d75554aba2c3e85f7ac75505dcd3349c 237 Gene3D G3DSA:3.40.50.880 7 232 8.9E-61 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_10055 d75554aba2c3e85f7ac75505dcd3349c 237 SUPERFAMILY SSF52317 9 225 1.99E-35 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_17280 15af68d8d1a3412e8c4ea1b4b46e45a5 339 SUPERFAMILY SSF56042 159 319 9.59E-30 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSH58p_17280 15af68d8d1a3412e8c4ea1b4b46e45a5 339 Pfam PF00586 AIR synthase related protein, N-terminal domain 40 152 1.0E-20 T 14-10-2018 IPR016188 PurM-like, N-terminal domain TSH58p_17280 15af68d8d1a3412e8c4ea1b4b46e45a5 339 Gene3D G3DSA:3.30.1330.10 14 158 9.4E-38 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSH58p_17280 15af68d8d1a3412e8c4ea1b4b46e45a5 339 Pfam PF02769 AIR synthase related protein, C-terminal domain 164 321 1.6E-9 T 14-10-2018 IPR010918 PurM-like, C-terminal domain TSH58p_17280 15af68d8d1a3412e8c4ea1b4b46e45a5 339 SUPERFAMILY SSF55326 14 152 6.93E-32 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSH58p_17280 15af68d8d1a3412e8c4ea1b4b46e45a5 339 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 15 339 26.399 T 14-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 TSH58p_17280 15af68d8d1a3412e8c4ea1b4b46e45a5 339 Gene3D G3DSA:3.90.650.10 160 339 1.9E-46 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSH58p_17280 15af68d8d1a3412e8c4ea1b4b46e45a5 339 PIRSF PIRSF005303 10 339 1.6E-74 T 14-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 TSH58p_17280 15af68d8d1a3412e8c4ea1b4b46e45a5 339 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 16 339 5.3E-85 T 14-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 TSH58p_04580 f66bf0b7bab0de235869c6e59efa2e2f 391 SUPERFAMILY SSF50331 257 389 2.47E-18 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSH58p_04580 f66bf0b7bab0de235869c6e59efa2e2f 391 Pfam PF08402 TOBE domain 299 389 1.6E-15 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TSH58p_04580 f66bf0b7bab0de235869c6e59efa2e2f 391 Gene3D G3DSA:3.40.50.300 18 258 1.8E-76 T 14-10-2018 TSH58p_04580 f66bf0b7bab0de235869c6e59efa2e2f 391 Pfam PF00005 ABC transporter 40 181 2.5E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_04580 f66bf0b7bab0de235869c6e59efa2e2f 391 SUPERFAMILY SSF52540 24 264 1.01E-87 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_04580 f66bf0b7bab0de235869c6e59efa2e2f 391 SMART SM00382 48 231 1.3E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_04580 f66bf0b7bab0de235869c6e59efa2e2f 391 Gene3D G3DSA:2.40.50.140 259 301 3.3E-8 T 14-10-2018 TSH58p_04580 f66bf0b7bab0de235869c6e59efa2e2f 391 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_04580 f66bf0b7bab0de235869c6e59efa2e2f 391 Gene3D G3DSA:2.40.50.100 302 380 3.3E-8 T 14-10-2018 TSH58p_04580 f66bf0b7bab0de235869c6e59efa2e2f 391 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 54 389 5.2E-128 T 14-10-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 TSH58p_02450 dbcca7055f2361858564f0c8855959ac 713 Pfam PF02743 Cache domain 145 334 9.8E-18 T 14-10-2018 IPR033479 Double Cache domain 1 TSH58p_02450 dbcca7055f2361858564f0c8855959ac 713 Gene3D G3DSA:1.20.1480.50 338 426 2.7E-6 T 14-10-2018 TSH58p_02450 dbcca7055f2361858564f0c8855959ac 713 SMART SM00044 414 612 3.9E-15 T 14-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 TSH58p_02450 dbcca7055f2361858564f0c8855959ac 713 SMART SM00304 372 425 0.0021 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_02450 dbcca7055f2361858564f0c8855959ac 713 SUPERFAMILY SSF55073 444 631 2.83E-55 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_02450 dbcca7055f2361858564f0c8855959ac 713 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 448 610 2.1E-28 T 14-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 TSH58p_02450 dbcca7055f2361858564f0c8855959ac 713 Gene3D G3DSA:3.30.70.1230 440 642 2.7E-61 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_02450 dbcca7055f2361858564f0c8855959ac 713 Gene3D G3DSA:3.30.450.20 204 337 3.2E-12 T 14-10-2018 TSH58p_28090 451cd1a1545b6c88717c269b2519295a 375 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 254 280 1.2E-66 T 14-10-2018 TSH58p_28090 451cd1a1545b6c88717c269b2519295a 375 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 212 229 1.2E-66 T 14-10-2018 TSH58p_28090 451cd1a1545b6c88717c269b2519295a 375 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 157 181 1.2E-66 T 14-10-2018 TSH58p_28090 451cd1a1545b6c88717c269b2519295a 375 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 45 67 1.2E-66 T 14-10-2018 TSH58p_28090 451cd1a1545b6c88717c269b2519295a 375 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 68 92 1.2E-66 T 14-10-2018 TSH58p_28090 451cd1a1545b6c88717c269b2519295a 375 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 114 137 1.2E-66 T 14-10-2018 TSH58p_28090 451cd1a1545b6c88717c269b2519295a 375 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 186 209 1.2E-66 T 14-10-2018 TSH58p_28090 451cd1a1545b6c88717c269b2519295a 375 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 230 248 1.2E-66 T 14-10-2018 TSH58p_28090 451cd1a1545b6c88717c269b2519295a 375 PIRSF PIRSF000310 7 367 6.2E-122 T 14-10-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 TSH58p_28090 451cd1a1545b6c88717c269b2519295a 375 SUPERFAMILY SSF56770 48 304 3.36E-80 T 14-10-2018 TSH58p_28090 451cd1a1545b6c88717c269b2519295a 375 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 225 305 1.0E-27 T 14-10-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal TSH58p_28090 451cd1a1545b6c88717c269b2519295a 375 Gene3D G3DSA:3.40.50.700 45 224 2.0E-64 T 14-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily TSH58p_28090 451cd1a1545b6c88717c269b2519295a 375 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 60 205 3.9E-27 T 14-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_28090 451cd1a1545b6c88717c269b2519295a 375 Gene3D G3DSA:4.10.480.10 227 350 3.2E-31 T 14-10-2018 IPR037148 [NiFe]-hydrogenase, small subunit, C-terminal domain superfamily TSH58p_28090 451cd1a1545b6c88717c269b2519295a 375 TIGRFAM TIGR00391 hydA: hydrogenase (NiFe) small subunit (hydA) 12 365 1.5E-132 T 14-10-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 TSH58p_28090 451cd1a1545b6c88717c269b2519295a 375 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 14 43 4.0E-4 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal TSH58p_02955 14fb32c18e4c18a9e8d834010d79c702 118 SUPERFAMILY SSF49472 2 118 1.14E-30 T 14-10-2018 IPR036817 Transthyretin/hydroxyisourate hydrolase domain superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 TSH58p_02955 14fb32c18e4c18a9e8d834010d79c702 118 Gene3D G3DSA:2.60.40.180 1 118 6.9E-26 T 14-10-2018 IPR036817 Transthyretin/hydroxyisourate hydrolase domain superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 TSH58p_02955 14fb32c18e4c18a9e8d834010d79c702 118 Pfam PF00576 HIUase/Transthyretin family 5 117 2.2E-22 T 14-10-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase domain Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 TSH58p_06885 1ca363a4522905db9a1ce8e367f37ff2 456 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 366 454 8.5E-16 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain TSH58p_06885 1ca363a4522905db9a1ce8e367f37ff2 456 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 6 436 2.0E-51 T 14-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G TSH58p_06885 1ca363a4522905db9a1ce8e367f37ff2 456 Pfam PF00460 Flagella basal body rod protein 7 37 6.5E-8 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 TSH58p_06885 1ca363a4522905db9a1ce8e367f37ff2 456 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 14-10-2018 IPR019776 Flagellar basal body rod protein, conserved site TSH58p_06885 1ca363a4522905db9a1ce8e367f37ff2 456 SUPERFAMILY SSF117143 81 390 8.37E-36 T 14-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like TSH58p_25045 fcbb17499a8a8e4cd6d258ee6aa8febf 656 SUPERFAMILY SSF53955 475 626 1.13E-41 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily TSH58p_25045 fcbb17499a8a8e4cd6d258ee6aa8febf 656 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 484 512 - T 14-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 TSH58p_25045 fcbb17499a8a8e4cd6d258ee6aa8febf 656 Pfam PF01464 Transglycosylase SLT domain 474 579 1.6E-25 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 TSH58p_25045 fcbb17499a8a8e4cd6d258ee6aa8febf 656 Gene3D G3DSA:1.25.40.10 181 366 1.5E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25045 fcbb17499a8a8e4cd6d258ee6aa8febf 656 Gene3D G3DSA:1.10.530.10 471 628 1.1E-42 T 14-10-2018 TSH58p_25045 fcbb17499a8a8e4cd6d258ee6aa8febf 656 SUPERFAMILY SSF48435 225 449 2.75E-22 T 14-10-2018 IPR008939 Lytic transglycosylase, superhelical U-shaped GO:0004553|GO:0042597 TSH58p_12590 a3385e0d155edfca21f728b101f885ac 490 Gene3D G3DSA:3.40.309.10 232 445 5.3E-47 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TSH58p_12590 a3385e0d155edfca21f728b101f885ac 490 SUPERFAMILY SSF53720 23 439 1.02E-91 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSH58p_12590 a3385e0d155edfca21f728b101f885ac 490 Gene3D G3DSA:3.40.605.10 20 231 5.5E-42 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TSH58p_12590 a3385e0d155edfca21f728b101f885ac 490 Pfam PF00171 Aldehyde dehydrogenase family 26 437 1.6E-80 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TSH58p_12590 a3385e0d155edfca21f728b101f885ac 490 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 225 232 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 TSH58p_30385 61ef1b6c1ab2438b1a6b5bee09426050 150 Pfam PF00034 Cytochrome c 50 134 1.8E-9 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_30385 61ef1b6c1ab2438b1a6b5bee09426050 150 Gene3D G3DSA:1.10.760.10 1 150 7.6E-38 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_30385 61ef1b6c1ab2438b1a6b5bee09426050 150 SUPERFAMILY SSF46626 25 146 6.35E-20 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_10620 b557b17376947617e013d68a7a7008db 200 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 13 196 3.7E-47 T 14-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 TSH58p_10620 b557b17376947617e013d68a7a7008db 200 Gene3D G3DSA:3.90.950.10 10 199 5.4E-64 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TSH58p_10620 b557b17376947617e013d68a7a7008db 200 Pfam PF01725 Ham1 family 13 196 1.2E-53 T 14-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 TSH58p_10620 b557b17376947617e013d68a7a7008db 200 SUPERFAMILY SSF52972 8 198 9.42E-65 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TSH58p_10620 b557b17376947617e013d68a7a7008db 200 Hamap MF_01405 dITP/XTP pyrophosphatase. 11 200 44.136 T 14-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 TSH58p_16975 dea0dd877fc9a7bccfe3019639d430d8 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 2.5E-30 T 14-10-2018 TSH58p_16975 dea0dd877fc9a7bccfe3019639d430d8 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 2.5E-30 T 14-10-2018 TSH58p_16975 dea0dd877fc9a7bccfe3019639d430d8 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 304 2.5E-30 T 14-10-2018 TSH58p_16975 dea0dd877fc9a7bccfe3019639d430d8 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 269 2.5E-30 T 14-10-2018 TSH58p_16975 dea0dd877fc9a7bccfe3019639d430d8 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 2.5E-30 T 14-10-2018 TSH58p_16975 dea0dd877fc9a7bccfe3019639d430d8 450 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 337 445 2.8E-33 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TSH58p_16975 dea0dd877fc9a7bccfe3019639d430d8 450 Gene3D G3DSA:3.50.50.60 6 320 8.1E-115 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_16975 dea0dd877fc9a7bccfe3019639d430d8 450 TIGRFAM TIGR01424 gluta_reduc_2: glutathione-disulfide reductase 4 446 1.7E-196 T 14-10-2018 IPR006324 Glutathione-disulphide reductase GO:0004362|GO:0006749|GO:0050660|GO:0050661|GO:0055114 KEGG: 00480+1.8.1.7|MetaCyc: PWY-4081 TSH58p_16975 dea0dd877fc9a7bccfe3019639d430d8 450 Gene3D G3DSA:3.30.390.30 336 450 3.3E-43 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TSH58p_16975 dea0dd877fc9a7bccfe3019639d430d8 450 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 14-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 TSH58p_16975 dea0dd877fc9a7bccfe3019639d430d8 450 SUPERFAMILY SSF51905 5 362 7.07E-56 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_16975 dea0dd877fc9a7bccfe3019639d430d8 450 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 317 6.2E-69 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSH58p_16975 dea0dd877fc9a7bccfe3019639d430d8 450 Gene3D G3DSA:3.50.50.60 144 260 8.1E-115 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_16975 dea0dd877fc9a7bccfe3019639d430d8 450 PIRSF PIRSF000350 2 445 8.2E-89 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 TSH58p_16975 dea0dd877fc9a7bccfe3019639d430d8 450 SUPERFAMILY SSF55424 334 447 5.67E-35 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TSH58p_16975 dea0dd877fc9a7bccfe3019639d430d8 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 420 440 9.2E-66 T 14-10-2018 TSH58p_16975 dea0dd877fc9a7bccfe3019639d430d8 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 194 9.2E-66 T 14-10-2018 TSH58p_16975 dea0dd877fc9a7bccfe3019639d430d8 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 333 354 9.2E-66 T 14-10-2018 TSH58p_16975 dea0dd877fc9a7bccfe3019639d430d8 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 9.2E-66 T 14-10-2018 TSH58p_16975 dea0dd877fc9a7bccfe3019639d430d8 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 135 144 9.2E-66 T 14-10-2018 TSH58p_16975 dea0dd877fc9a7bccfe3019639d430d8 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 9.2E-66 T 14-10-2018 TSH58p_16975 dea0dd877fc9a7bccfe3019639d430d8 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 304 9.2E-66 T 14-10-2018 TSH58p_16975 dea0dd877fc9a7bccfe3019639d430d8 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 254 268 9.2E-66 T 14-10-2018 TSH58p_16975 dea0dd877fc9a7bccfe3019639d430d8 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 398 413 9.2E-66 T 14-10-2018 TSH58p_23930 9e71e361f5712fbdc8e780c780cdb3e6 417 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 189 241 3.1E-9 T 14-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 TSH58p_23930 9e71e361f5712fbdc8e780c780cdb3e6 417 SUPERFAMILY SSF81891 152 414 8.89E-44 T 14-10-2018 TSH58p_23930 9e71e361f5712fbdc8e780c780cdb3e6 417 Gene3D G3DSA:1.10.3090.10 152 309 5.0E-31 T 14-10-2018 TSH58p_23930 9e71e361f5712fbdc8e780c780cdb3e6 417 SUPERFAMILY SSF81301 8 150 5.56E-40 T 14-10-2018 TSH58p_23930 9e71e361f5712fbdc8e780c780cdb3e6 417 Pfam PF01743 Poly A polymerase head domain 33 154 4.2E-31 T 14-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 TSH58p_23930 9e71e361f5712fbdc8e780c780cdb3e6 417 Gene3D G3DSA:3.30.460.10 7 150 3.6E-42 T 14-10-2018 TSH58p_26560 53e9373075de32a722b334566e1c85dd 390 SUPERFAMILY SSF56935 22 381 3.97E-25 T 14-10-2018 TSH58p_26560 53e9373075de32a722b334566e1c85dd 390 Pfam PF13609 Gram-negative porin 14 363 1.3E-34 T 14-10-2018 TSH58p_26560 53e9373075de32a722b334566e1c85dd 390 Gene3D G3DSA:2.40.160.10 31 374 3.0E-32 T 14-10-2018 IPR023614 Porin domain superfamily TSH58p_03745 f27430620e83024e1c3cc444f3da9fc0 83 Gene3D G3DSA:1.10.260.40 1 77 1.4E-23 T 14-10-2018 TSH58p_03745 f27430620e83024e1c3cc444f3da9fc0 83 Pfam PF01381 Helix-turn-helix 9 53 8.9E-8 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_03745 f27430620e83024e1c3cc444f3da9fc0 83 SUPERFAMILY SSF47413 6 67 1.46E-7 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_26415 c1958a3ba94fa08592d783dcb33e14f6 272 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 31 271 4.9E-71 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 TSH58p_26415 c1958a3ba94fa08592d783dcb33e14f6 272 Pfam PF02634 FdhD/NarQ family 34 270 2.2E-75 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 TSH58p_26415 c1958a3ba94fa08592d783dcb33e14f6 272 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 10 272 34.167 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 TSH58p_26415 c1958a3ba94fa08592d783dcb33e14f6 272 Gene3D G3DSA:3.10.20.10 36 122 5.5E-11 T 14-10-2018 TSH58p_26415 c1958a3ba94fa08592d783dcb33e14f6 272 SUPERFAMILY SSF53927 13 270 1.23E-80 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TSH58p_26415 c1958a3ba94fa08592d783dcb33e14f6 272 PIRSF PIRSF015626 5 272 8.1E-78 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 TSH58p_26415 c1958a3ba94fa08592d783dcb33e14f6 272 Gene3D G3DSA:3.40.140.10 126 272 1.3E-49 T 14-10-2018 TSH58p_04195 6ab4714aae9d2a8a948b7b589fcbb2ea 307 Gene3D G3DSA:3.40.50.300 22 213 3.4E-27 T 14-10-2018 TSH58p_04195 6ab4714aae9d2a8a948b7b589fcbb2ea 307 Pfam PF07728 AAA domain (dynein-related subfamily) 41 195 2.2E-10 T 14-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 TSH58p_04195 6ab4714aae9d2a8a948b7b589fcbb2ea 307 SUPERFAMILY SSF52540 39 285 2.09E-34 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_20200 5e9272c2f86488e413962ba0cfa7c779 244 Gene3D G3DSA:1.25.60.10 141 218 2.8E-5 T 14-10-2018 IPR038076 MgtE, N-terminal domain superfamily TSH58p_20200 5e9272c2f86488e413962ba0cfa7c779 244 SUPERFAMILY SSF158791 154 216 2.49E-7 T 14-10-2018 TSH58p_29885 176ae1d637074b37c9a2f0f2250ee506 443 Gene3D G3DSA:3.30.559.10 203 440 1.3E-91 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TSH58p_29885 176ae1d637074b37c9a2f0f2250ee506 443 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 TSH58p_29885 176ae1d637074b37c9a2f0f2250ee506 443 TIGRFAM TIGR01349 PDHac_trf_mito: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase 5 443 3.8E-169 T 14-10-2018 IPR006257 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex GO:0004742|GO:0006090|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-70268 TSH58p_29885 176ae1d637074b37c9a2f0f2250ee506 443 Pfam PF02817 e3 binding domain 132 167 2.2E-17 T 14-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 TSH58p_29885 176ae1d637074b37c9a2f0f2250ee506 443 SUPERFAMILY SSF51230 1 97 1.83E-29 T 14-10-2018 IPR011053 Single hybrid motif TSH58p_29885 176ae1d637074b37c9a2f0f2250ee506 443 SUPERFAMILY SSF52777 218 443 4.14E-81 T 14-10-2018 TSH58p_29885 176ae1d637074b37c9a2f0f2250ee506 443 Gene3D G3DSA:4.10.320.10 120 174 3.4E-19 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TSH58p_29885 176ae1d637074b37c9a2f0f2250ee506 443 Pfam PF00364 Biotin-requiring enzyme 4 77 1.5E-20 T 14-10-2018 IPR000089 Biotin/lipoyl attachment TSH58p_29885 176ae1d637074b37c9a2f0f2250ee506 443 Gene3D G3DSA:2.40.50.100 2 103 1.4E-33 T 14-10-2018 TSH58p_29885 176ae1d637074b37c9a2f0f2250ee506 443 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 219 443 3.2E-84 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 TSH58p_29885 176ae1d637074b37c9a2f0f2250ee506 443 SUPERFAMILY SSF47005 125 170 3.4E-13 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TSH58p_16315 f0730ef2409920a5679e9179a8062336 450 SUPERFAMILY SSF69304 171 447 1.06E-58 T 14-10-2018 TSH58p_16315 f0730ef2409920a5679e9179a8062336 450 SUPERFAMILY SSF52964 39 174 7.85E-44 T 14-10-2018 TSH58p_16315 f0730ef2409920a5679e9179a8062336 450 Pfam PF07676 WD40-like Beta Propeller Repeat 295 330 2.8E-12 T 14-10-2018 IPR011659 WD40-like Beta Propeller TSH58p_16315 f0730ef2409920a5679e9179a8062336 450 Pfam PF07676 WD40-like Beta Propeller Repeat 338 370 2.9E-7 T 14-10-2018 IPR011659 WD40-like Beta Propeller TSH58p_16315 f0730ef2409920a5679e9179a8062336 450 Pfam PF07676 WD40-like Beta Propeller Repeat 382 415 0.0073 T 14-10-2018 IPR011659 WD40-like Beta Propeller TSH58p_16315 f0730ef2409920a5679e9179a8062336 450 Pfam PF07676 WD40-like Beta Propeller Repeat 259 285 0.0029 T 14-10-2018 IPR011659 WD40-like Beta Propeller TSH58p_16315 f0730ef2409920a5679e9179a8062336 450 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 28 446 3.1E-143 T 14-10-2018 IPR014167 Tol-Pal system protein TolB GO:0017038|GO:0042597 TSH58p_16315 f0730ef2409920a5679e9179a8062336 450 Gene3D G3DSA:2.120.10.30 178 449 1.4E-75 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TSH58p_16315 f0730ef2409920a5679e9179a8062336 450 Hamap MF_00671 Tol-Pal system protein TolB [tolB]. 15 445 51.013 T 14-10-2018 IPR014167 Tol-Pal system protein TolB GO:0017038|GO:0042597 TSH58p_16315 f0730ef2409920a5679e9179a8062336 450 Pfam PF04052 TolB amino-terminal domain 34 141 3.3E-36 T 14-10-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 TSH58p_16315 f0730ef2409920a5679e9179a8062336 450 Gene3D G3DSA:3.40.50.10070 30 177 4.6E-43 T 14-10-2018 IPR036752 TolB, N-terminal domain superfamily GO:0015031|GO:0042597 TSH58p_12165 6dcf03b2110233daa651e4c69fbf96e2 336 Gene3D G3DSA:1.20.58.340 260 336 5.3E-27 T 14-10-2018 TSH58p_12165 6dcf03b2110233daa651e4c69fbf96e2 336 Pfam PF01544 CorA-like Mg2+ transporter protein 27 332 3.1E-55 T 14-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 TSH58p_12165 6dcf03b2110233daa651e4c69fbf96e2 336 SUPERFAMILY SSF143865 1 275 2.48E-35 T 14-10-2018 TSH58p_12165 6dcf03b2110233daa651e4c69fbf96e2 336 SUPERFAMILY SSF144083 271 333 5.49E-21 T 14-10-2018 TSH58p_21945 3e502bab22759b1d2d0ac13edaa30cc8 397 Pfam PF01435 Peptidase family M48 75 256 1.5E-26 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 TSH58p_21945 3e502bab22759b1d2d0ac13edaa30cc8 397 SUPERFAMILY SSF48452 254 383 7.09E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_21945 3e502bab22759b1d2d0ac13edaa30cc8 397 Gene3D G3DSA:1.25.40.10 205 396 8.3E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_03645 ff68010d18757eeb99db9315f056c3e8 125 Gene3D G3DSA:3.40.50.2300 1 124 6.1E-27 T 14-10-2018 TSH58p_03645 ff68010d18757eeb99db9315f056c3e8 125 SMART SM00448 5 113 4.6E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_03645 ff68010d18757eeb99db9315f056c3e8 125 Pfam PF00072 Response regulator receiver domain 7 110 3.0E-18 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_03645 ff68010d18757eeb99db9315f056c3e8 125 SUPERFAMILY SSF52172 3 121 4.27E-29 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_27310 6ceb512dc8f012efceb2503af07c61f2 379 PIRSF PIRSF005622 1 374 3.1E-155 T 14-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 TSH58p_27310 6ceb512dc8f012efceb2503af07c61f2 379 Gene3D G3DSA:3.40.50.11750 22 265 2.5E-104 T 14-10-2018 TSH58p_27310 6ceb512dc8f012efceb2503af07c61f2 379 Gene3D G3DSA:1.10.10.2140 320 371 7.4E-25 T 14-10-2018 TSH58p_27310 6ceb512dc8f012efceb2503af07c61f2 379 Gene3D G3DSA:3.40.50.11740 61 306 2.5E-104 T 14-10-2018 TSH58p_27310 6ceb512dc8f012efceb2503af07c61f2 379 Pfam PF01924 Hydrogenase formation hypA family 12 369 2.7E-153 T 14-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 TSH58p_27310 6ceb512dc8f012efceb2503af07c61f2 379 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 2 372 4.6E-140 T 14-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 TSH58p_04605 557363523b8ef8a0a3eaa2c22c569cca 446 SUPERFAMILY SSF63380 233 317 5.3E-14 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TSH58p_04605 557363523b8ef8a0a3eaa2c22c569cca 446 Gene3D G3DSA:3.40.50.80 318 446 6.2E-16 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TSH58p_04605 557363523b8ef8a0a3eaa2c22c569cca 446 Pfam PF01794 Ferric reductase like transmembrane component 43 177 1.7E-19 T 14-10-2018 IPR013130 Ferric reductase transmembrane component-like domain TSH58p_04605 557363523b8ef8a0a3eaa2c22c569cca 446 Pfam PF08022 FAD-binding domain 238 314 3.0E-6 T 14-10-2018 IPR013112 FAD-binding 8 GO:0016491|GO:0055114 TSH58p_04605 557363523b8ef8a0a3eaa2c22c569cca 446 Gene3D G3DSA:2.40.30.10 224 314 3.2E-11 T 14-10-2018 TSH58p_04605 557363523b8ef8a0a3eaa2c22c569cca 446 PRINTS PR00409 Phthalate dioxygenase reductase family signature 410 418 6.3E-6 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 TSH58p_04605 557363523b8ef8a0a3eaa2c22c569cca 446 PRINTS PR00409 Phthalate dioxygenase reductase family signature 304 318 6.3E-6 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 TSH58p_04605 557363523b8ef8a0a3eaa2c22c569cca 446 PRINTS PR00409 Phthalate dioxygenase reductase family signature 326 345 6.3E-6 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 TSH58p_04605 557363523b8ef8a0a3eaa2c22c569cca 446 SUPERFAMILY SSF52343 306 437 3.14E-18 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TSH58p_15995 7ec531aa4ae2cc5cf3df204a82e61eab 54 Hamap MF_01361 UPF0391 membrane protein YtjA [ytjA]. 1 50 20.453 T 14-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 TSH58p_15995 7ec531aa4ae2cc5cf3df204a82e61eab 54 PIRSF PIRSF036466 1 54 1.3E-22 T 14-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 TSH58p_15995 7ec531aa4ae2cc5cf3df204a82e61eab 54 Pfam PF07043 Protein of unknown function (DUF1328) 6 42 1.7E-14 T 14-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 TSH58p_20420 ab1ca06af362e74d2d5498e9f81d4107 395 Gene3D G3DSA:1.20.1250.20 1 386 2.6E-40 T 14-10-2018 TSH58p_20420 ab1ca06af362e74d2d5498e9f81d4107 395 SUPERFAMILY SSF103473 2 383 1.57E-50 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_20420 ab1ca06af362e74d2d5498e9f81d4107 395 Pfam PF07690 Major Facilitator Superfamily 6 346 5.5E-27 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_24040 6d3ee8d2c6d344aa8e255f24f3975bf0 475 SUPERFAMILY SSF55124 13 96 3.6E-21 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TSH58p_24040 6d3ee8d2c6d344aa8e255f24f3975bf0 475 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 409 425 - T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TSH58p_24040 6d3ee8d2c6d344aa8e255f24f3975bf0 475 SUPERFAMILY SSF55124 293 350 6.35E-5 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TSH58p_24040 6d3ee8d2c6d344aa8e255f24f3975bf0 475 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 104 241 8.6E-7 T 14-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TSH58p_24040 6d3ee8d2c6d344aa8e255f24f3975bf0 475 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 28 93 5.3E-14 T 14-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TSH58p_24040 6d3ee8d2c6d344aa8e255f24f3975bf0 475 TIGRFAM TIGR02435 CobG: precorrin-3B synthase 18 429 3.8E-86 T 14-10-2018 IPR012798 Cobalamin (vitamin B12) biosynthesis CobG-like TSH58p_24040 6d3ee8d2c6d344aa8e255f24f3975bf0 475 Gene3D G3DSA:3.90.480.10 36 343 2.7E-47 T 14-10-2018 TSH58p_24040 6d3ee8d2c6d344aa8e255f24f3975bf0 475 Gene3D G3DSA:3.30.413.10 364 463 7.0E-11 T 14-10-2018 TSH58p_24040 6d3ee8d2c6d344aa8e255f24f3975bf0 475 SUPERFAMILY SSF56014 106 244 1.37E-19 T 14-10-2018 TSH58p_24040 6d3ee8d2c6d344aa8e255f24f3975bf0 475 SUPERFAMILY SSF56014 366 450 4.06E-12 T 14-10-2018 TSH58p_24040 6d3ee8d2c6d344aa8e255f24f3975bf0 475 Gene3D G3DSA:3.30.413.10 102 279 2.7E-47 T 14-10-2018 TSH58p_12485 88a10dc9075673f535674f032d9362bc 148 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 133 3.3E-34 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 TSH58p_12485 88a10dc9075673f535674f032d9362bc 148 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 98 107 9.9E-9 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 TSH58p_12485 88a10dc9075673f535674f032d9362bc 148 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 89 97 9.9E-9 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 TSH58p_12485 88a10dc9075673f535674f032d9362bc 148 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 9.9E-9 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 TSH58p_12485 88a10dc9075673f535674f032d9362bc 148 SUPERFAMILY SSF81330 11 129 1.16E-34 T 14-10-2018 IPR036019 Gated mechanosensitive channel TSH58p_12485 88a10dc9075673f535674f032d9362bc 148 Gene3D G3DSA:1.10.1200.120 1 136 1.8E-40 T 14-10-2018 IPR036019 Gated mechanosensitive channel TSH58p_12485 88a10dc9075673f535674f032d9362bc 148 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 132 3.6E-42 T 14-10-2018 IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L TSH58p_12485 88a10dc9075673f535674f032d9362bc 148 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 134 22.828 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 TSH58p_31730 0c29834997e5598b7929a70ead1b438c 206 Pfam PF00805 Pentapeptide repeats (8 copies) 79 118 4.7E-12 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_31730 0c29834997e5598b7929a70ead1b438c 206 Pfam PF00805 Pentapeptide repeats (8 copies) 159 198 2.8E-10 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_31730 0c29834997e5598b7929a70ead1b438c 206 Pfam PF00805 Pentapeptide repeats (8 copies) 119 158 1.5E-8 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_31730 0c29834997e5598b7929a70ead1b438c 206 SUPERFAMILY SSF141571 56 199 6.18E-37 T 14-10-2018 TSH58p_31730 0c29834997e5598b7929a70ead1b438c 206 Gene3D G3DSA:2.160.20.80 41 206 4.9E-42 T 14-10-2018 TSH58p_20400 528e77f3ea662a41fe966c4caaa828da 415 Gene3D G3DSA:3.40.50.1820 112 412 3.2E-22 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_20400 528e77f3ea662a41fe966c4caaa828da 415 Pfam PF00561 alpha/beta hydrolase fold 130 391 1.8E-10 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_20400 528e77f3ea662a41fe966c4caaa828da 415 SUPERFAMILY SSF53474 121 412 2.23E-31 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_26760 9dad8b33ceca4d7bf487eb345ca37f22 225 SUPERFAMILY SSF48008 73 201 2.62E-21 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_26760 9dad8b33ceca4d7bf487eb345ca37f22 225 Gene3D G3DSA:1.10.10.10 1 67 3.4E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_26760 9dad8b33ceca4d7bf487eb345ca37f22 225 SMART SM00345 8 66 4.4E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_26760 9dad8b33ceca4d7bf487eb345ca37f22 225 SMART SM00895 76 198 9.7E-9 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_26760 9dad8b33ceca4d7bf487eb345ca37f22 225 Pfam PF07729 FCD domain 78 198 4.5E-15 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_26760 9dad8b33ceca4d7bf487eb345ca37f22 225 Gene3D G3DSA:1.20.120.530 69 208 4.9E-21 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_26760 9dad8b33ceca4d7bf487eb345ca37f22 225 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 66 9.1E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_26760 9dad8b33ceca4d7bf487eb345ca37f22 225 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 1.8E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_26760 9dad8b33ceca4d7bf487eb345ca37f22 225 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 1.8E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_26760 9dad8b33ceca4d7bf487eb345ca37f22 225 SUPERFAMILY SSF46785 5 79 5.13E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_29540 b463750753d889ae8c117585e525a467 315 SUPERFAMILY SSF52833 31 150 4.48E-17 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_29540 b463750753d889ae8c117585e525a467 315 SUPERFAMILY SSF47616 166 312 6.13E-36 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily TSH58p_29540 b463750753d889ae8c117585e525a467 315 Gene3D G3DSA:3.40.30.130 1 168 3.1E-70 T 14-10-2018 TSH58p_29540 b463750753d889ae8c117585e525a467 315 Gene3D G3DSA:1.20.1050.10 169 315 2.4E-70 T 14-10-2018 TSH58p_29540 b463750753d889ae8c117585e525a467 315 Pfam PF13409 Glutathione S-transferase, N-terminal domain 56 146 5.2E-24 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 TSH58p_29540 b463750753d889ae8c117585e525a467 315 Pfam PF13410 Glutathione S-transferase, C-terminal domain 194 263 1.0E-12 T 14-10-2018 TSH58p_29540 b463750753d889ae8c117585e525a467 315 PIRSF PIRSF015753 5 312 1.6E-132 T 14-10-2018 IPR016639 Glutathione S-transferase Omega/GSH GO:0004364 TSH58p_26945 0cae7366c05e0c732d92095f1caa2b10 103 Pfam PF04341 Protein of unknown function, DUF485 11 98 1.6E-26 T 14-10-2018 IPR007436 Protein of unknown function DUF485 TSH58p_14485 de56193e748fef8e90e98284e3456179 295 SUPERFAMILY SSF55681 15 290 2.06E-134 T 14-10-2018 TSH58p_14485 de56193e748fef8e90e98284e3456179 295 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 120 144 2.1E-66 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TSH58p_14485 de56193e748fef8e90e98284e3456179 295 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 255 271 2.1E-66 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TSH58p_14485 de56193e748fef8e90e98284e3456179 295 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 146 166 2.1E-66 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TSH58p_14485 de56193e748fef8e90e98284e3456179 295 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 89 109 2.1E-66 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TSH58p_14485 de56193e748fef8e90e98284e3456179 295 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 68 83 2.1E-66 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TSH58p_14485 de56193e748fef8e90e98284e3456179 295 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 169 184 2.1E-66 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TSH58p_14485 de56193e748fef8e90e98284e3456179 295 Gene3D G3DSA:3.30.930.10 5 218 7.7E-110 T 14-10-2018 TSH58p_14485 de56193e748fef8e90e98284e3456179 295 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 15 290 8.0E-146 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TSH58p_14485 de56193e748fef8e90e98284e3456179 295 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 16 290 9.6E-151 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TSH58p_14485 de56193e748fef8e90e98284e3456179 295 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 14 295 58.61 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TSH58p_14485 de56193e748fef8e90e98284e3456179 295 Gene3D G3DSA:1.20.58.180 219 292 1.4E-33 T 14-10-2018 TSH58p_01815 884ac24dce04ba9178dae0ad099d79aa 262 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 43 259 1.8E-64 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_01815 884ac24dce04ba9178dae0ad099d79aa 262 SUPERFAMILY SSF53850 8 259 9.32E-71 T 14-10-2018 TSH58p_01815 884ac24dce04ba9178dae0ad099d79aa 262 Gene3D G3DSA:3.40.190.10 127 220 4.2E-72 T 14-10-2018 TSH58p_01815 884ac24dce04ba9178dae0ad099d79aa 262 SMART SM00062 41 261 1.4E-71 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_01815 884ac24dce04ba9178dae0ad099d79aa 262 SMART SM00079 41 260 1.3E-4 T 14-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 TSH58p_01815 884ac24dce04ba9178dae0ad099d79aa 262 Gene3D G3DSA:3.40.190.10 44 258 4.2E-72 T 14-10-2018 TSH58p_01815 884ac24dce04ba9178dae0ad099d79aa 262 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 63 76 - T 14-10-2018 IPR018313 Solute-binding protein family 3, conserved site TSH58p_15495 94ab4507049f0815767fd441a1504263 99 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 63 79 5.8E-5 T 14-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 TSH58p_15495 94ab4507049f0815767fd441a1504263 99 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 84 97 5.8E-5 T 14-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 TSH58p_15495 94ab4507049f0815767fd441a1504263 99 Pfam PF02049 Flagellar hook-basal body complex protein FliE 14 99 3.9E-23 T 14-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 TSH58p_15495 94ab4507049f0815767fd441a1504263 99 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 13 98 3.1E-15 T 14-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 TSH58p_15495 94ab4507049f0815767fd441a1504263 99 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 3 99 15.216 T 14-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 TSH58p_19560 b08c4687c1a4a25265565b4dd266f0f5 580 Gene3D G3DSA:3.40.50.2300 2 102 5.4E-13 T 14-10-2018 TSH58p_19560 b08c4687c1a4a25265565b4dd266f0f5 580 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 116 205 6.9E-18 T 14-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TSH58p_19560 b08c4687c1a4a25265565b4dd266f0f5 580 Gene3D G3DSA:3.40.50.2300 103 212 2.1E-38 T 14-10-2018 TSH58p_19560 b08c4687c1a4a25265565b4dd266f0f5 580 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 115 198 1.1E-34 T 14-10-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202 TSH58p_19560 b08c4687c1a4a25265565b4dd266f0f5 580 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 234 571 1.2E-139 T 14-10-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 TSH58p_19560 b08c4687c1a4a25265565b4dd266f0f5 580 SUPERFAMILY SSF52794 4 101 3.4E-19 T 14-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 TSH58p_19560 b08c4687c1a4a25265565b4dd266f0f5 580 Pfam PF02378 Phosphotransferase system, EIIC 248 515 9.0E-16 T 14-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 TSH58p_19560 b08c4687c1a4a25265565b4dd266f0f5 580 SUPERFAMILY SSF52794 113 213 1.74E-35 T 14-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 TSH58p_00725 8736a1940ce866172ff4b1a57afade9e 362 Gene3D G3DSA:3.40.50.300 4 228 2.9E-51 T 14-10-2018 TSH58p_00725 8736a1940ce866172ff4b1a57afade9e 362 Pfam PF00005 ABC transporter 28 168 1.2E-19 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_00725 8736a1940ce866172ff4b1a57afade9e 362 Gene3D G3DSA:2.40.50.940 229 352 5.0E-17 T 14-10-2018 TSH58p_00725 8736a1940ce866172ff4b1a57afade9e 362 Gene3D G3DSA:2.40.50.140 289 343 5.0E-17 T 14-10-2018 TSH58p_00725 8736a1940ce866172ff4b1a57afade9e 362 SUPERFAMILY SSF52540 21 249 2.42E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_00725 8736a1940ce866172ff4b1a57afade9e 362 SUPERFAMILY SSF50331 243 354 3.97E-18 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSH58p_00725 8736a1940ce866172ff4b1a57afade9e 362 SMART SM00382 34 218 1.0E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_16925 55ce13b98f65a60714d989b91f9846fc 290 Pfam PF11306 Protein of unknown function (DUF3108) 30 275 2.3E-26 T 14-10-2018 IPR021457 Protein of unknown function DUF3108 TSH58p_28905 9a6f3148de21b065678962e057da5977 321 SUPERFAMILY SSF53850 93 295 9.41E-45 T 14-10-2018 TSH58p_28905 9a6f3148de21b065678962e057da5977 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 2.5E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_28905 9a6f3148de21b065678962e057da5977 321 SUPERFAMILY SSF46785 2 86 9.83E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_28905 9a6f3148de21b065678962e057da5977 321 Pfam PF03466 LysR substrate binding domain 93 292 9.8E-44 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_28905 9a6f3148de21b065678962e057da5977 321 Gene3D G3DSA:1.10.10.10 7 91 1.7E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_28905 9a6f3148de21b065678962e057da5977 321 Gene3D G3DSA:3.40.190.10 103 288 2.2E-64 T 14-10-2018 TSH58p_28905 9a6f3148de21b065678962e057da5977 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.2E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_28905 9a6f3148de21b065678962e057da5977 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.2E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_28905 9a6f3148de21b065678962e057da5977 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.2E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_28905 9a6f3148de21b065678962e057da5977 321 Gene3D G3DSA:3.40.190.10 163 261 2.2E-64 T 14-10-2018 TSH58p_30615 f9f805641e14409a4ab431687980a5cb 560 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 37 59 6.3E-7 T 14-10-2018 TSH58p_30615 f9f805641e14409a4ab431687980a5cb 560 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 364 371 6.3E-7 T 14-10-2018 TSH58p_30615 f9f805641e14409a4ab431687980a5cb 560 Pfam PF00890 FAD binding domain 37 243 2.7E-23 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_30615 f9f805641e14409a4ab431687980a5cb 560 Gene3D G3DSA:1.20.58.100 422 520 6.1E-14 T 14-10-2018 TSH58p_30615 f9f805641e14409a4ab431687980a5cb 560 PIRSF PIRSF000171 290 543 1.4E-10 T 14-10-2018 TSH58p_30615 f9f805641e14409a4ab431687980a5cb 560 PIRSF PIRSF000171 27 274 7.7E-23 T 14-10-2018 TSH58p_30615 f9f805641e14409a4ab431687980a5cb 560 SUPERFAMILY SSF51905 29 406 5.46E-43 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_30615 f9f805641e14409a4ab431687980a5cb 560 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 349 371 4.6E-16 T 14-10-2018 TSH58p_30615 f9f805641e14409a4ab431687980a5cb 560 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 38 57 4.6E-16 T 14-10-2018 TSH58p_30615 f9f805641e14409a4ab431687980a5cb 560 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 201 219 4.6E-16 T 14-10-2018 TSH58p_30615 f9f805641e14409a4ab431687980a5cb 560 Gene3D G3DSA:3.50.50.60 27 264 1.8E-45 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_30615 f9f805641e14409a4ab431687980a5cb 560 Pfam PF02910 Fumarate reductase flavoprotein C-term 449 521 9.3E-8 T 14-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_30615 f9f805641e14409a4ab431687980a5cb 560 SUPERFAMILY SSF46977 432 544 3.79E-22 T 14-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSH58p_31435 17dadde712f9c329a30003a7f51eeb52 297 Pfam PF00701 Dihydrodipicolinate synthetase family 4 288 1.4E-65 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_31435 17dadde712f9c329a30003a7f51eeb52 297 SUPERFAMILY SSF51569 1 292 1.15E-86 T 14-10-2018 TSH58p_31435 17dadde712f9c329a30003a7f51eeb52 297 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 7 281 4.0E-62 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSH58p_31435 17dadde712f9c329a30003a7f51eeb52 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 38 59 1.4E-20 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_31435 17dadde712f9c329a30003a7f51eeb52 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 74 92 1.4E-20 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_31435 17dadde712f9c329a30003a7f51eeb52 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 131 148 1.4E-20 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_31435 17dadde712f9c329a30003a7f51eeb52 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 106 122 1.4E-20 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_31435 17dadde712f9c329a30003a7f51eeb52 297 SMART SM01130 3 291 1.1E-107 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_31435 17dadde712f9c329a30003a7f51eeb52 297 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 41 58 - T 14-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSH58p_31435 17dadde712f9c329a30003a7f51eeb52 297 Gene3D G3DSA:3.20.20.70 2 291 1.0E-93 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_31435 17dadde712f9c329a30003a7f51eeb52 297 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 3 289 40.19 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSH58p_31435 17dadde712f9c329a30003a7f51eeb52 297 PIRSF PIRSF001365 1 296 6.0E-89 T 14-10-2018 IPR002220 DapA-like GO:0016829 TSH58p_06965 0ce12953c97f1a56f2f9fdf066ebb86a 163 Pfam PF00583 Acetyltransferase (GNAT) family 21 137 1.1E-18 T 14-10-2018 IPR000182 GNAT domain TSH58p_06965 0ce12953c97f1a56f2f9fdf066ebb86a 163 Gene3D G3DSA:3.40.630.30 1 163 3.1E-54 T 14-10-2018 TSH58p_06965 0ce12953c97f1a56f2f9fdf066ebb86a 163 SUPERFAMILY SSF55729 4 150 9.09E-38 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_31630 2f142f3da3e8dafe94870c86fa2b8452 295 Gene3D G3DSA:3.40.50.1980 24 147 8.6E-39 T 14-10-2018 TSH58p_31630 2f142f3da3e8dafe94870c86fa2b8452 295 Gene3D G3DSA:3.40.50.1980 150 288 1.6E-31 T 14-10-2018 TSH58p_31630 2f142f3da3e8dafe94870c86fa2b8452 295 SUPERFAMILY SSF53807 28 284 3.81E-49 T 14-10-2018 TSH58p_31630 2f142f3da3e8dafe94870c86fa2b8452 295 Pfam PF01497 Periplasmic binding protein 30 265 1.3E-32 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain TSH58p_04655 b9f3c39bc4fe11d001f89f0885d07720 191 Pfam PF00583 Acetyltransferase (GNAT) family 44 137 1.6E-13 T 14-10-2018 IPR000182 GNAT domain TSH58p_04655 b9f3c39bc4fe11d001f89f0885d07720 191 SUPERFAMILY SSF55729 15 170 2.4E-24 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_04655 b9f3c39bc4fe11d001f89f0885d07720 191 Gene3D G3DSA:3.40.630.30 12 174 5.3E-22 T 14-10-2018 TSH58p_17870 99237888c130864439dc01749e8f5ac0 604 Pfam PF13489 Methyltransferase domain 102 247 1.2E-10 T 14-10-2018 TSH58p_17870 99237888c130864439dc01749e8f5ac0 604 Gene3D G3DSA:3.40.50.150 84 256 3.8E-20 T 14-10-2018 TSH58p_17870 99237888c130864439dc01749e8f5ac0 604 SUPERFAMILY SSF53335 94 255 2.29E-20 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_21255 dcd9b6834f82a07bf2e65f61895ae67c 438 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 16 434 4.3E-161 T 14-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 TSH58p_21255 dcd9b6834f82a07bf2e65f61895ae67c 438 SUPERFAMILY SSF53383 9 436 1.75E-116 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_21255 dcd9b6834f82a07bf2e65f61895ae67c 438 Pfam PF00202 Aminotransferase class-III 27 433 8.1E-104 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSH58p_21255 dcd9b6834f82a07bf2e65f61895ae67c 438 Gene3D G3DSA:3.90.1150.10 13 428 2.1E-146 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_21255 dcd9b6834f82a07bf2e65f61895ae67c 438 Gene3D G3DSA:3.40.640.10 64 338 2.1E-146 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_21255 dcd9b6834f82a07bf2e65f61895ae67c 438 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 249 286 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSH58p_25435 593968b8a9d79edd2e00a66732c11deb 97 Pfam PF14110 Domain of unknown function (DUF4282) 4 83 2.8E-14 T 14-10-2018 IPR025557 Protein of unknown function DUF4282 TSH58p_13915 b8859b1fa972e4ffcef094b738e26bcb 252 Gene3D G3DSA:1.10.3720.10 45 236 7.1E-25 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_13915 b8859b1fa972e4ffcef094b738e26bcb 252 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 231 1.6E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_13915 b8859b1fa972e4ffcef094b738e26bcb 252 SUPERFAMILY SSF161098 48 231 4.71E-31 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_22120 b04d1a2588b0186b2ac9ddaa15f5e9cf 322 Pfam PF07786 Protein of unknown function (DUF1624) 20 236 2.8E-64 T 14-10-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-2206291|Reactome: R-HSA-6798695 TSH58p_27105 38f2f16846f6b7769a3d016653dcd445 213 Pfam PF13417 Glutathione S-transferase, N-terminal domain 23 84 3.3E-9 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 TSH58p_27105 38f2f16846f6b7769a3d016653dcd445 213 SUPERFAMILY SSF52833 8 91 1.97E-13 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_27105 38f2f16846f6b7769a3d016653dcd445 213 Gene3D G3DSA:1.20.1050.10 88 198 7.7E-45 T 14-10-2018 TSH58p_27105 38f2f16846f6b7769a3d016653dcd445 213 SUPERFAMILY SSF47616 87 205 1.09E-17 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily TSH58p_27105 38f2f16846f6b7769a3d016653dcd445 213 Gene3D G3DSA:3.40.30.10 8 202 7.7E-45 T 14-10-2018 TSH58p_23300 407000e38f78028dabe8e17243c0a2e7 295 Gene3D G3DSA:1.25.40.590 68 223 1.1E-26 T 14-10-2018 IPR038522 Type IV / VI secretion system, DotU superfamily TSH58p_23300 407000e38f78028dabe8e17243c0a2e7 295 Pfam PF09850 Type VI secretion system protein DotU 73 272 1.6E-21 T 14-10-2018 IPR017732 Type IV / VI secretion system, DotU TSH58p_01260 50354260a7d54d3cef5208657d275bae 279 Gene3D G3DSA:3.40.430.10 19 275 3.9E-41 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TSH58p_01260 50354260a7d54d3cef5208657d275bae 279 SUPERFAMILY SSF53597 36 253 1.71E-26 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TSH58p_01260 50354260a7d54d3cef5208657d275bae 279 Pfam PF01872 RibD C-terminal domain 36 243 2.4E-14 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 TSH58p_12960 deea5288c5a43f318562cc4c26cd84c9 500 Gene3D G3DSA:3.40.50.620 191 324 1.2E-5 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_12960 deea5288c5a43f318562cc4c26cd84c9 500 SUPERFAMILY SSF52402 191 293 1.15E-7 T 14-10-2018 TSH58p_18990 850f8693ccd707e378fbe884ca81af31 494 SUPERFAMILY SSF53659 190 472 5.35E-71 T 14-10-2018 TSH58p_18990 850f8693ccd707e378fbe884ca81af31 494 Gene3D G3DSA:3.40.718.10 178 473 2.9E-98 T 14-10-2018 TSH58p_18990 850f8693ccd707e378fbe884ca81af31 494 Pfam PF01575 MaoC like domain 36 132 7.4E-18 T 14-10-2018 IPR002539 MaoC-like dehydratase domain TSH58p_18990 850f8693ccd707e378fbe884ca81af31 494 Gene3D G3DSA:3.10.129.10 20 174 4.8E-44 T 14-10-2018 TSH58p_18990 850f8693ccd707e378fbe884ca81af31 494 Pfam PF01515 Phosphate acetyl/butaryl transferase 254 469 1.2E-47 T 14-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 TSH58p_18990 850f8693ccd707e378fbe884ca81af31 494 SUPERFAMILY SSF54637 23 160 1.15E-39 T 14-10-2018 IPR029069 HotDog domain superfamily TSH58p_17150 f49b5ff72ceaa74dbed3995095af9ff6 608 Gene3D G3DSA:3.40.50.300 1 197 1.7E-62 T 14-10-2018 TSH58p_17150 f49b5ff72ceaa74dbed3995095af9ff6 608 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 148 1.2E-23 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSH58p_17150 f49b5ff72ceaa74dbed3995095af9ff6 608 SUPERFAMILY SSF54980 400 514 2.83E-25 T 14-10-2018 IPR035647 EF-G domain III/V-like TSH58p_17150 f49b5ff72ceaa74dbed3995095af9ff6 608 Pfam PF00679 Elongation factor G C-terminus 399 482 4.0E-20 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like TSH58p_17150 f49b5ff72ceaa74dbed3995095af9ff6 608 Gene3D G3DSA:3.30.70.870 306 591 3.6E-130 T 14-10-2018 TSH58p_17150 f49b5ff72ceaa74dbed3995095af9ff6 608 Gene3D G3DSA:2.40.30.10 198 299 2.2E-31 T 14-10-2018 TSH58p_17150 f49b5ff72ceaa74dbed3995095af9ff6 608 Gene3D G3DSA:2.40.50.250 484 600 3.6E-130 T 14-10-2018 TSH58p_17150 f49b5ff72ceaa74dbed3995095af9ff6 608 Pfam PF00009 Elongation factor Tu GTP binding domain 2 194 2.0E-54 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_17150 f49b5ff72ceaa74dbed3995095af9ff6 608 SUPERFAMILY SSF50447 150 297 5.82E-29 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSH58p_17150 f49b5ff72ceaa74dbed3995095af9ff6 608 PRINTS PR00315 GTP-binding elongation factor signature 85 96 4.8E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_17150 f49b5ff72ceaa74dbed3995095af9ff6 608 PRINTS PR00315 GTP-binding elongation factor signature 49 57 4.8E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_17150 f49b5ff72ceaa74dbed3995095af9ff6 608 PRINTS PR00315 GTP-binding elongation factor signature 69 79 4.8E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_17150 f49b5ff72ceaa74dbed3995095af9ff6 608 PRINTS PR00315 GTP-binding elongation factor signature 121 130 4.8E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_17150 f49b5ff72ceaa74dbed3995095af9ff6 608 PRINTS PR00315 GTP-binding elongation factor signature 5 18 4.8E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSH58p_17150 f49b5ff72ceaa74dbed3995095af9ff6 608 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 3 600 2.7E-282 T 14-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 TSH58p_17150 f49b5ff72ceaa74dbed3995095af9ff6 608 SUPERFAMILY SSF52540 3 205 5.06E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_17150 f49b5ff72ceaa74dbed3995095af9ff6 608 SUPERFAMILY SSF54980 302 387 7.67E-13 T 14-10-2018 IPR035647 EF-G domain III/V-like TSH58p_17150 f49b5ff72ceaa74dbed3995095af9ff6 608 Pfam PF03144 Elongation factor Tu domain 2 218 289 1.3E-11 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TSH58p_17150 f49b5ff72ceaa74dbed3995095af9ff6 608 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 42 57 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site TSH58p_17150 f49b5ff72ceaa74dbed3995095af9ff6 608 Gene3D G3DSA:3.30.70.240 389 483 3.6E-130 T 14-10-2018 TSH58p_32360 9a87b98a4dd51e001dce29304cf8631c 347 Gene3D G3DSA:3.40.50.300 4 258 2.5E-76 T 14-10-2018 TSH58p_32360 9a87b98a4dd51e001dce29304cf8631c 347 SUPERFAMILY SSF50331 237 343 2.15E-12 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSH58p_32360 9a87b98a4dd51e001dce29304cf8631c 347 Pfam PF00005 ABC transporter 19 161 8.8E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_32360 9a87b98a4dd51e001dce29304cf8631c 347 SMART SM00382 28 211 1.8E-20 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_32360 9a87b98a4dd51e001dce29304cf8631c 347 SUPERFAMILY SSF52540 4 243 7.45E-86 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_32360 9a87b98a4dd51e001dce29304cf8631c 347 Pfam PF08402 TOBE domain 273 343 1.9E-11 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TSH58p_32360 9a87b98a4dd51e001dce29304cf8631c 347 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_07230 0afc92526eb6eaa2e6940a9580012787 313 SUPERFAMILY SSF52096 79 292 1.7E-29 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_07230 0afc92526eb6eaa2e6940a9580012787 313 Gene3D G3DSA:3.40.1750.20 192 258 4.1E-50 T 14-10-2018 TSH58p_07230 0afc92526eb6eaa2e6940a9580012787 313 Gene3D G3DSA:3.90.226.10 85 297 4.1E-50 T 14-10-2018 TSH58p_07230 0afc92526eb6eaa2e6940a9580012787 313 Pfam PF01343 Peptidase family S49 155 299 7.0E-34 T 14-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 TSH58p_23760 28dbfeb454900b81e54775b0ba6edb4b 243 PIRSF PIRSF003073 1 243 2.3E-65 T 14-10-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein TSH58p_23760 28dbfeb454900b81e54775b0ba6edb4b 243 SUPERFAMILY SSF52540 94 230 3.99E-19 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_23760 28dbfeb454900b81e54775b0ba6edb4b 243 Pfam PF01695 IstB-like ATP binding protein 54 229 1.1E-49 T 14-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 TSH58p_23760 28dbfeb454900b81e54775b0ba6edb4b 243 Gene3D G3DSA:3.40.50.300 61 243 1.7E-34 T 14-10-2018 TSH58p_23760 28dbfeb454900b81e54775b0ba6edb4b 243 SMART SM00382 97 230 2.1E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_16185 6c7b50a06a0ff9a07505f1639032cc51 281 SUPERFAMILY SSF56655 6 261 3.4E-80 T 14-10-2018 TSH58p_16185 6c7b50a06a0ff9a07505f1639032cc51 281 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 84 97 - T 14-10-2018 IPR020583 Inositol monophosphatase, metal-binding site TSH58p_16185 6c7b50a06a0ff9a07505f1639032cc51 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 84 100 1.3E-56 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_16185 6c7b50a06a0ff9a07505f1639032cc51 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 211 235 1.3E-56 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_16185 6c7b50a06a0ff9a07505f1639032cc51 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 133 156 1.3E-56 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_16185 6c7b50a06a0ff9a07505f1639032cc51 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 41 61 1.3E-56 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_16185 6c7b50a06a0ff9a07505f1639032cc51 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 63 79 1.3E-56 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_16185 6c7b50a06a0ff9a07505f1639032cc51 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 180 201 1.3E-56 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_16185 6c7b50a06a0ff9a07505f1639032cc51 281 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 214 228 - T 14-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 TSH58p_16185 6c7b50a06a0ff9a07505f1639032cc51 281 Gene3D G3DSA:3.40.190.80 144 263 4.1E-33 T 14-10-2018 TSH58p_16185 6c7b50a06a0ff9a07505f1639032cc51 281 Pfam PF00459 Inositol monophosphatase family 7 250 2.4E-61 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_16185 6c7b50a06a0ff9a07505f1639032cc51 281 Gene3D G3DSA:3.30.540.10 1 143 5.8E-54 T 14-10-2018 TSH58p_16185 6c7b50a06a0ff9a07505f1639032cc51 281 PRINTS PR01959 SuhB family inositol monophosphatase signature 107 126 2.1E-25 T 14-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 TSH58p_16185 6c7b50a06a0ff9a07505f1639032cc51 281 PRINTS PR01959 SuhB family inositol monophosphatase signature 201 213 2.1E-25 T 14-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 TSH58p_16185 6c7b50a06a0ff9a07505f1639032cc51 281 PRINTS PR01959 SuhB family inositol monophosphatase signature 159 185 2.1E-25 T 14-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 TSH58p_16185 6c7b50a06a0ff9a07505f1639032cc51 281 PRINTS PR01959 SuhB family inositol monophosphatase signature 20 42 2.1E-25 T 14-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 TSH58p_08430 19bb1f5d253395b2601b02947730e767 278 Pfam PF09865 Predicted periplasmic protein (DUF2092) 50 261 4.1E-71 T 14-10-2018 IPR019207 Protein of unknown function DUF2092, periplasmic TSH58p_08430 19bb1f5d253395b2601b02947730e767 278 Gene3D G3DSA:2.50.20.10 52 259 7.4E-10 T 14-10-2018 TSH58p_08430 19bb1f5d253395b2601b02947730e767 278 SUPERFAMILY SSF89392 54 259 7.85E-12 T 14-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX TSH58p_04495 990a52d21c18c15bbc67e58f8e6e8a0a 885 Gene3D G3DSA:3.40.50.620 24 532 0.0 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_04495 990a52d21c18c15bbc67e58f8e6e8a0a 885 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 17 570 9.4E-216 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_04495 990a52d21c18c15bbc67e58f8e6e8a0a 885 Pfam PF08264 Anticodon-binding domain of tRNA 613 759 6.8E-38 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TSH58p_04495 990a52d21c18c15bbc67e58f8e6e8a0a 885 SUPERFAMILY SSF46589 819 883 2.98E-16 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 TSH58p_04495 990a52d21c18c15bbc67e58f8e6e8a0a 885 Hamap MF_02004 Valine--tRNA ligase [valS]. 4 884 16.111 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TSH58p_04495 990a52d21c18c15bbc67e58f8e6e8a0a 885 SUPERFAMILY SSF47323 584 834 6.92E-57 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_04495 990a52d21c18c15bbc67e58f8e6e8a0a 885 Gene3D G3DSA:1.10.730.10 4 747 0.0 T 14-10-2018 TSH58p_04495 990a52d21c18c15bbc67e58f8e6e8a0a 885 SUPERFAMILY SSF52374 5 581 2.94E-140 T 14-10-2018 TSH58p_04495 990a52d21c18c15bbc67e58f8e6e8a0a 885 PRINTS PR00986 Valyl-tRNA synthetase signature 452 473 3.1E-38 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TSH58p_04495 990a52d21c18c15bbc67e58f8e6e8a0a 885 PRINTS PR00986 Valyl-tRNA synthetase signature 483 501 3.1E-38 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TSH58p_04495 990a52d21c18c15bbc67e58f8e6e8a0a 885 PRINTS PR00986 Valyl-tRNA synthetase signature 233 250 3.1E-38 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TSH58p_04495 990a52d21c18c15bbc67e58f8e6e8a0a 885 PRINTS PR00986 Valyl-tRNA synthetase signature 350 363 3.1E-38 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TSH58p_04495 990a52d21c18c15bbc67e58f8e6e8a0a 885 PRINTS PR00986 Valyl-tRNA synthetase signature 38 49 3.1E-38 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TSH58p_04495 990a52d21c18c15bbc67e58f8e6e8a0a 885 TIGRFAM TIGR00422 valS: valine--tRNA ligase 5 863 0.0 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TSH58p_04495 990a52d21c18c15bbc67e58f8e6e8a0a 885 Gene3D G3DSA:1.10.287.380 812 884 1.0E-21 T 14-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 TSH58p_04495 990a52d21c18c15bbc67e58f8e6e8a0a 885 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 45 56 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSH58p_04495 990a52d21c18c15bbc67e58f8e6e8a0a 885 SUPERFAMILY SSF50677 193 346 5.62E-63 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TSH58p_04495 990a52d21c18c15bbc67e58f8e6e8a0a 885 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 819 883 9.6E-20 T 14-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 TSH58p_04495 990a52d21c18c15bbc67e58f8e6e8a0a 885 Gene3D G3DSA:3.90.740.10 177 346 0.0 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TSH58p_23885 4a73595b219113e8749d54781b900abc 119 SMART SM00418 15 93 8.6E-26 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSH58p_23885 4a73595b219113e8749d54781b900abc 119 SUPERFAMILY SSF46785 11 96 2.87E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_23885 4a73595b219113e8749d54781b900abc 119 Pfam PF01022 Bacterial regulatory protein, arsR family 23 67 7.8E-14 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSH58p_23885 4a73595b219113e8749d54781b900abc 119 Gene3D G3DSA:1.10.10.10 2 102 3.5E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_23885 4a73595b219113e8749d54781b900abc 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 64 79 2.9E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSH58p_23885 4a73595b219113e8749d54781b900abc 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 17 32 2.9E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSH58p_23885 4a73595b219113e8749d54781b900abc 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 2.9E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSH58p_31870 a9395f883524210573b95a6ca80a1756 324 Gene3D G3DSA:3.40.190.10 116 295 1.0E-77 T 14-10-2018 TSH58p_31870 a9395f883524210573b95a6ca80a1756 324 Pfam PF13343 Bacterial extracellular solute-binding protein 85 303 8.9E-30 T 14-10-2018 TSH58p_31870 a9395f883524210573b95a6ca80a1756 324 PIRSF PIRSF002825 4 322 1.8E-70 T 14-10-2018 IPR026045 Ferric binding protein TSH58p_31870 a9395f883524210573b95a6ca80a1756 324 SUPERFAMILY SSF53850 10 319 1.21E-62 T 14-10-2018 TSH58p_31870 a9395f883524210573b95a6ca80a1756 324 Gene3D G3DSA:3.40.190.10 17 289 1.0E-77 T 14-10-2018 TSH58p_01215 dc5e5bd64c8238329fe92a2bd210820c 309 Gene3D G3DSA:1.10.4200.10 38 286 2.1E-55 T 14-10-2018 TSH58p_01215 dc5e5bd64c8238329fe92a2bd210820c 309 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 18 280 6.0E-63 T 14-10-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 TSH58p_31890 1dd1b96af0cdb2a8eaee45b4f3eec862 273 SUPERFAMILY SSF53955 9 166 4.35E-48 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily TSH58p_31890 1dd1b96af0cdb2a8eaee45b4f3eec862 273 Gene3D G3DSA:1.10.530.40 11 169 1.1E-49 T 14-10-2018 TSH58p_31890 1dd1b96af0cdb2a8eaee45b4f3eec862 273 Pfam PF00959 Phage lysozyme 34 156 1.7E-15 T 14-10-2018 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 TSH58p_16600 404aab669a87401d5428c2f0689bb4ba 521 Pfam PF14326 Domain of unknown function (DUF4384) 387 465 7.4E-20 T 14-10-2018 IPR025493 Domain of unknown function DUF4384 TSH58p_16600 404aab669a87401d5428c2f0689bb4ba 521 Pfam PF01471 Putative peptidoglycan binding domain 281 335 4.4E-8 T 14-10-2018 IPR002477 Peptidoglycan binding-like TSH58p_16600 404aab669a87401d5428c2f0689bb4ba 521 Gene3D G3DSA:1.10.101.10 269 337 3.3E-6 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 TSH58p_16600 404aab669a87401d5428c2f0689bb4ba 521 SUPERFAMILY SSF47090 280 336 8.32E-11 T 14-10-2018 IPR036365 PGBD-like superfamily TSH58p_26075 de4b06427b9c51fe089c24479f1da1c0 516 Gene3D G3DSA:1.20.970.10 193 250 1.2E-17 T 14-10-2018 TSH58p_26075 de4b06427b9c51fe089c24479f1da1c0 516 SUPERFAMILY SSF47648 194 248 9.68E-14 T 14-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSH58p_26075 de4b06427b9c51fe089c24479f1da1c0 516 SUPERFAMILY SSF46785 43 118 3.88E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_26075 de4b06427b9c51fe089c24479f1da1c0 516 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 43 101 4.5E-15 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_26075 de4b06427b9c51fe089c24479f1da1c0 516 Gene3D G3DSA:1.10.10.10 37 120 6.0E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_26075 de4b06427b9c51fe089c24479f1da1c0 516 Pfam PF02885 Glycosyl transferase family, helical bundle domain 195 247 1.1E-14 T 14-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSH58p_26075 de4b06427b9c51fe089c24479f1da1c0 516 Gene3D G3DSA:3.40.1030.10 276 512 2.6E-28 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSH58p_26075 de4b06427b9c51fe089c24479f1da1c0 516 SUPERFAMILY SSF52418 258 505 1.96E-34 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSH58p_18260 edf7f2641cecb423cd0fa382b471f32a 430 SUPERFAMILY SSF51735 5 191 1.66E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_18260 edf7f2641cecb423cd0fa382b471f32a 430 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 317 418 3.3E-20 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSH58p_18260 edf7f2641cecb423cd0fa382b471f32a 430 SUPERFAMILY SSF52413 300 417 5.62E-23 T 14-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 TSH58p_18260 edf7f2641cecb423cd0fa382b471f32a 430 PIRSF PIRSF500136 1 429 1.4E-140 T 14-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 TSH58p_18260 edf7f2641cecb423cd0fa382b471f32a 430 SUPERFAMILY SSF48179 200 291 1.31E-24 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_18260 edf7f2641cecb423cd0fa382b471f32a 430 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 6 406 2.6E-115 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 TSH58p_18260 edf7f2641cecb423cd0fa382b471f32a 430 PIRSF PIRSF000124 5 417 9.9E-49 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 TSH58p_18260 edf7f2641cecb423cd0fa382b471f32a 430 Gene3D G3DSA:3.40.50.720 200 425 6.2E-51 T 14-10-2018 TSH58p_18260 edf7f2641cecb423cd0fa382b471f32a 430 SMART SM00984 317 418 1.9E-30 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSH58p_18260 edf7f2641cecb423cd0fa382b471f32a 430 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 6 179 4.5E-33 T 14-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSH58p_18260 edf7f2641cecb423cd0fa382b471f32a 430 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 201 289 6.2E-24 T 14-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TSH58p_18260 edf7f2641cecb423cd0fa382b471f32a 430 Gene3D G3DSA:3.40.50.720 1 197 1.4E-59 T 14-10-2018 TSH58p_16980 119364e457a9eacc94a244a51c75e9e2 165 Pfam PF03748 Flagellar basal body-associated protein FliL 72 164 8.4E-9 T 14-10-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 TSH58p_27440 ea21acf1c60c60856331e1b466fe97fe 503 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 24 451 3.5E-97 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSH58p_27440 ea21acf1c60c60856331e1b466fe97fe 503 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 14 450 1.5E-126 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TSH58p_15675 2de15d5ae9b3abd7c51e93aaee00c413 113 Gene3D G3DSA:3.40.30.10 1 113 1.7E-42 T 14-10-2018 TSH58p_15675 2de15d5ae9b3abd7c51e93aaee00c413 113 Pfam PF03960 ArsC family 62 112 1.8E-11 T 14-10-2018 IPR006660 Arsenate reductase-like TSH58p_15675 2de15d5ae9b3abd7c51e93aaee00c413 113 SUPERFAMILY SSF52833 3 113 5.79E-30 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_15675 2de15d5ae9b3abd7c51e93aaee00c413 113 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 4 113 1.9E-38 T 14-10-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 TSH58p_19730 1d190aab2e85271f4404c932dee392e7 591 TIGRFAM TIGR03457 sulphoacet_xsc: sulfoacetaldehyde acetyltransferase 2 577 5.0E-299 T 14-10-2018 IPR017820 Sulphoacetaldehyde acetyltransferase GO:0000287|GO:0005737|GO:0019529|GO:0030976|GO:0050487 KEGG: 00430+2.3.3.15|MetaCyc: PWY-1281|MetaCyc: PWY-6637 TSH58p_19730 1d190aab2e85271f4404c932dee392e7 591 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 441 460 - T 14-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 TSH58p_19730 1d190aab2e85271f4404c932dee392e7 591 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 404 554 2.6E-28 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TSH58p_19730 1d190aab2e85271f4404c932dee392e7 591 Gene3D G3DSA:3.40.50.970 1 181 1.2E-45 T 14-10-2018 TSH58p_19730 1d190aab2e85271f4404c932dee392e7 591 SUPERFAMILY SSF52518 378 588 5.68E-46 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_19730 1d190aab2e85271f4404c932dee392e7 591 Gene3D G3DSA:3.40.50.1220 183 361 6.4E-45 T 14-10-2018 TSH58p_19730 1d190aab2e85271f4404c932dee392e7 591 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 187 324 2.2E-32 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 TSH58p_19730 1d190aab2e85271f4404c932dee392e7 591 SUPERFAMILY SSF52518 1 179 6.34E-42 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_19730 1d190aab2e85271f4404c932dee392e7 591 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 168 4.5E-41 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 TSH58p_19730 1d190aab2e85271f4404c932dee392e7 591 Gene3D G3DSA:3.40.50.970 373 572 9.6E-46 T 14-10-2018 TSH58p_19730 1d190aab2e85271f4404c932dee392e7 591 SUPERFAMILY SSF52467 153 356 5.82E-41 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TSH58p_20520 6185229cc993bceea5e3732e0252e8c8 281 Gene3D G3DSA:3.30.450.40 102 278 9.4E-51 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_20520 6185229cc993bceea5e3732e0252e8c8 281 Pfam PF09339 IclR helix-turn-helix domain 33 83 1.5E-16 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TSH58p_20520 6185229cc993bceea5e3732e0252e8c8 281 SUPERFAMILY SSF46785 31 102 7.7E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_20520 6185229cc993bceea5e3732e0252e8c8 281 Gene3D G3DSA:1.10.10.10 31 92 2.8E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_20520 6185229cc993bceea5e3732e0252e8c8 281 SUPERFAMILY SSF55781 96 277 2.16E-43 T 14-10-2018 TSH58p_20520 6185229cc993bceea5e3732e0252e8c8 281 SMART SM00346 31 121 2.3E-21 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TSH58p_20520 6185229cc993bceea5e3732e0252e8c8 281 Pfam PF01614 Bacterial transcriptional regulator 157 272 5.1E-31 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal TSH58p_20530 8e7a9539a5247631501c35ad08764bba 153 Pfam PF00376 MerR family regulatory protein 14 50 1.5E-13 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_20530 8e7a9539a5247631501c35ad08764bba 153 ProSitePatterns PS00552 MerR-type HTH domain signature. 16 38 - T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_20530 8e7a9539a5247631501c35ad08764bba 153 Gene3D G3DSA:1.10.1660.10 6 136 1.2E-33 T 14-10-2018 TSH58p_20530 8e7a9539a5247631501c35ad08764bba 153 Pfam PF09278 MerR, DNA binding 55 120 6.7E-18 T 14-10-2018 IPR015358 Transcription regulator MerR, DNA binding TSH58p_20530 8e7a9539a5247631501c35ad08764bba 153 SMART SM00422 13 81 6.3E-25 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_20530 8e7a9539a5247631501c35ad08764bba 153 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 13 151 5.8E-68 T 14-10-2018 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 TSH58p_20530 8e7a9539a5247631501c35ad08764bba 153 SUPERFAMILY SSF46955 13 135 6.23E-29 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily TSH58p_20530 8e7a9539a5247631501c35ad08764bba 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 25 9.2E-13 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_20530 8e7a9539a5247631501c35ad08764bba 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 48 68 9.2E-13 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_20530 8e7a9539a5247631501c35ad08764bba 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 25 38 9.2E-13 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_02460 db916dfd57a47e69b6f148dad9185e36 847 SUPERFAMILY SSF103473 437 835 3.79E-31 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_02460 db916dfd57a47e69b6f148dad9185e36 847 Pfam PF07690 Major Facilitator Superfamily 437 756 9.2E-14 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_02460 db916dfd57a47e69b6f148dad9185e36 847 Gene3D G3DSA:1.20.1250.20 434 830 2.2E-25 T 14-10-2018 TSH58p_06565 45b7acc52fc4c8a343257d6e4c77078e 384 Hamap MF_02040 Iron-sulfur cluster carrier protein. 116 365 38.863 T 14-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein TSH58p_06565 45b7acc52fc4c8a343257d6e4c77078e 384 Gene3D G3DSA:3.30.300.130 1 95 2.1E-10 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TSH58p_06565 45b7acc52fc4c8a343257d6e4c77078e 384 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 122 364 1.8E-106 T 14-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 TSH58p_06565 45b7acc52fc4c8a343257d6e4c77078e 384 ProSitePatterns PS01215 Mrp family signature. 228 244 - T 14-10-2018 IPR000808 Mrp, conserved site GO:0005524 TSH58p_06565 45b7acc52fc4c8a343257d6e4c77078e 384 SUPERFAMILY SSF52540 125 369 9.14E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_06565 45b7acc52fc4c8a343257d6e4c77078e 384 Gene3D G3DSA:3.40.50.300 109 363 1.6E-88 T 14-10-2018 TSH58p_06565 45b7acc52fc4c8a343257d6e4c77078e 384 SUPERFAMILY SSF117916 2 93 2.32E-19 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TSH58p_06565 45b7acc52fc4c8a343257d6e4c77078e 384 Pfam PF01883 Iron-sulfur cluster assembly protein 6 76 9.3E-21 T 14-10-2018 IPR002744 MIP18 family-like TSH58p_27600 0ecd818c42e22d2e352d28e28a44ab0b 554 Pfam PF01514 Secretory protein of YscJ/FliF family 24 213 2.9E-68 T 14-10-2018 IPR006182 Secretory protein YscJ/FliF TSH58p_27600 0ecd818c42e22d2e352d28e28a44ab0b 554 Pfam PF08345 Flagellar M-ring protein C-terminal 247 412 2.7E-44 T 14-10-2018 IPR013556 Flagellar M-ring C-terminal TSH58p_27600 0ecd818c42e22d2e352d28e28a44ab0b 554 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 22 476 1.1E-92 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 TSH58p_27600 0ecd818c42e22d2e352d28e28a44ab0b 554 Gene3D G3DSA:3.30.300.30 115 213 1.7E-13 T 14-10-2018 TSH58p_27600 0ecd818c42e22d2e352d28e28a44ab0b 554 PIRSF PIRSF004862 1 554 1.2E-138 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 TSH58p_27600 0ecd818c42e22d2e352d28e28a44ab0b 554 PRINTS PR01009 Flagellar M-ring protein signature 260 278 9.3E-38 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 TSH58p_27600 0ecd818c42e22d2e352d28e28a44ab0b 554 PRINTS PR01009 Flagellar M-ring protein signature 335 359 9.3E-38 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 TSH58p_27600 0ecd818c42e22d2e352d28e28a44ab0b 554 PRINTS PR01009 Flagellar M-ring protein signature 146 160 9.3E-38 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 TSH58p_27600 0ecd818c42e22d2e352d28e28a44ab0b 554 PRINTS PR01009 Flagellar M-ring protein signature 114 132 9.3E-38 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 TSH58p_27600 0ecd818c42e22d2e352d28e28a44ab0b 554 PRINTS PR01009 Flagellar M-ring protein signature 189 207 9.3E-38 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 TSH58p_17950 5fd077fd6dc276d9581b62fbb9eb0c36 611 Pfam PF00999 Sodium/hydrogen exchanger family 11 390 3.9E-74 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TSH58p_17950 5fd077fd6dc276d9581b62fbb9eb0c36 611 Pfam PF02254 TrkA-N domain 432 545 6.7E-25 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TSH58p_17950 5fd077fd6dc276d9581b62fbb9eb0c36 611 Gene3D G3DSA:3.40.50.720 428 584 3.1E-35 T 14-10-2018 TSH58p_17950 5fd077fd6dc276d9581b62fbb9eb0c36 611 Gene3D G3DSA:1.20.1530.20 4 399 3.4E-73 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily TSH58p_17950 5fd077fd6dc276d9581b62fbb9eb0c36 611 SUPERFAMILY SSF51735 430 560 5.81E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_02560 613eb1d48d8aa4be1e61326249f5ab0b 83 SUPERFAMILY SSF47598 1 43 3.56E-11 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TSH58p_02560 613eb1d48d8aa4be1e61326249f5ab0b 83 TIGRFAM TIGR02606 antidote_CC2985: putative addiction module antidote protein, CC2985 family 3 68 7.9E-18 T 14-10-2018 IPR022789 Antitoxin ParD TSH58p_02560 613eb1d48d8aa4be1e61326249f5ab0b 83 Pfam PF03693 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 6 44 2.7E-8 T 14-10-2018 IPR022789 Antitoxin ParD TSH58p_02560 613eb1d48d8aa4be1e61326249f5ab0b 83 Gene3D G3DSA:1.10.8.1250 10 82 6.2E-13 T 14-10-2018 IPR038296 Antitoxin ParD superfamily TSH58p_23245 44724a66ce60b1808858b6307af94fe7 299 SUPERFAMILY SSF103481 188 285 3.79E-12 T 14-10-2018 TSH58p_23245 44724a66ce60b1808858b6307af94fe7 299 SUPERFAMILY SSF103481 38 141 4.18E-15 T 14-10-2018 TSH58p_23245 44724a66ce60b1808858b6307af94fe7 299 Pfam PF00892 EamA-like transporter family 152 285 3.2E-18 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_23245 44724a66ce60b1808858b6307af94fe7 299 Pfam PF00892 EamA-like transporter family 5 137 9.6E-21 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_14810 5db4a60330f1d7e40562fd295b8eb4ec 1070 SUPERFAMILY SSF50249 40 232 3.52E-15 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_14810 5db4a60330f1d7e40562fd295b8eb4ec 1070 Pfam PF10150 Ribonuclease E/G family 228 499 3.3E-96 T 14-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 TSH58p_14810 5db4a60330f1d7e40562fd295b8eb4ec 1070 Gene3D G3DSA:2.40.50.140 36 123 7.3E-24 T 14-10-2018 TSH58p_14810 5db4a60330f1d7e40562fd295b8eb4ec 1070 Gene3D G3DSA:2.40.50.140 153 226 2.5E-13 T 14-10-2018 TSH58p_14810 5db4a60330f1d7e40562fd295b8eb4ec 1070 Hamap MF_00970 Ribonuclease E [rne]. 2 1070 32.897 T 14-10-2018 IPR028878 Ribonuclease E GO:0006396|GO:0008995 TSH58p_14810 5db4a60330f1d7e40562fd295b8eb4ec 1070 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 14 533 1.1E-161 T 14-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 TSH58p_14810 5db4a60330f1d7e40562fd295b8eb4ec 1070 Pfam PF00575 S1 RNA binding domain 39 78 1.4E-4 T 14-10-2018 IPR003029 S1 domain GO:0003676 TSH58p_14810 5db4a60330f1d7e40562fd295b8eb4ec 1070 Gene3D G3DSA:3.40.1260.20 509 616 7.5E-32 T 14-10-2018 TSH58p_32110 66956bdb5268ee3a0c66cfb22cfb68c6 290 Pfam PF05621 Bacterial TniB protein 21 265 6.1E-55 T 14-10-2018 IPR008868 Bacterial TniB TSH58p_32110 66956bdb5268ee3a0c66cfb22cfb68c6 290 Gene3D G3DSA:3.40.50.300 20 197 2.9E-5 T 14-10-2018 TSH58p_32110 66956bdb5268ee3a0c66cfb22cfb68c6 290 SUPERFAMILY SSF52540 28 269 4.03E-9 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_16180 938439404448be41d16ce4846adbc0da 263 Gene3D G3DSA:3.30.1330.60 141 251 4.4E-11 T 14-10-2018 IPR036737 OmpA-like domain superfamily TSH58p_16180 938439404448be41d16ce4846adbc0da 263 SUPERFAMILY SSF103088 157 247 5.76E-11 T 14-10-2018 IPR036737 OmpA-like domain superfamily TSH58p_16180 938439404448be41d16ce4846adbc0da 263 Pfam PF00691 OmpA family 168 246 1.6E-7 T 14-10-2018 IPR006665 OmpA-like domain TSH58p_31930 b66c4289b5e77edadff466dbe40317a6 397 SUPERFAMILY SSF89796 8 397 3.92E-137 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily TSH58p_31930 b66c4289b5e77edadff466dbe40317a6 397 Gene3D G3DSA:3.40.50.10540 10 391 8.2E-138 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily TSH58p_31930 b66c4289b5e77edadff466dbe40317a6 397 Pfam PF02515 CoA-transferase family III 10 374 3.4E-129 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 TSH58p_31930 b66c4289b5e77edadff466dbe40317a6 397 Gene3D G3DSA:3.30.1540.10 229 326 8.2E-138 T 14-10-2018 TSH58p_08345 01a411bb9c9e4fddab2bf3e8321c1e53 234 Pfam PF07729 FCD domain 86 207 2.3E-20 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_08345 01a411bb9c9e4fddab2bf3e8321c1e53 234 SMART SM00345 18 76 1.9E-11 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_08345 01a411bb9c9e4fddab2bf3e8321c1e53 234 SUPERFAMILY SSF46785 11 80 5.46E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_08345 01a411bb9c9e4fddab2bf3e8321c1e53 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 72 8.2E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_08345 01a411bb9c9e4fddab2bf3e8321c1e53 234 Gene3D G3DSA:1.10.10.10 1 77 4.4E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_08345 01a411bb9c9e4fddab2bf3e8321c1e53 234 SUPERFAMILY SSF48008 82 212 4.97E-23 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_08345 01a411bb9c9e4fddab2bf3e8321c1e53 234 SMART SM00895 86 208 4.1E-16 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_08345 01a411bb9c9e4fddab2bf3e8321c1e53 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 5.8E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_08345 01a411bb9c9e4fddab2bf3e8321c1e53 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 5.8E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_08345 01a411bb9c9e4fddab2bf3e8321c1e53 234 Gene3D G3DSA:1.20.120.530 80 218 5.6E-24 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_31545 1ef3c312d8017d3e430de3564e0dd942 352 Gene3D G3DSA:3.40.190.10 39 317 1.2E-60 T 14-10-2018 TSH58p_31545 1ef3c312d8017d3e430de3564e0dd942 352 SUPERFAMILY SSF53850 36 270 6.16E-39 T 14-10-2018 TSH58p_31545 1ef3c312d8017d3e430de3564e0dd942 352 Gene3D G3DSA:3.40.190.10 120 226 1.2E-60 T 14-10-2018 TSH58p_31545 1ef3c312d8017d3e430de3564e0dd942 352 Pfam PF09084 NMT1/THI5 like 49 265 1.3E-41 T 14-10-2018 IPR015168 SsuA/THI5-like TSH58p_15935 df369438b309e2e1e9ebecc59fdc2c08 430 Pfam PF00709 Adenylosuccinate synthetase 4 422 6.4E-173 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TSH58p_15935 df369438b309e2e1e9ebecc59fdc2c08 430 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 430 207.792 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TSH58p_15935 df369438b309e2e1e9ebecc59fdc2c08 430 Gene3D G3DSA:1.10.300.10 108 206 1.8E-90 T 14-10-2018 TSH58p_15935 df369438b309e2e1e9ebecc59fdc2c08 430 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 6 428 1.1E-159 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TSH58p_15935 df369438b309e2e1e9ebecc59fdc2c08 430 SUPERFAMILY SSF52540 1 424 3.61E-169 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_15935 df369438b309e2e1e9ebecc59fdc2c08 430 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 133 144 - T 14-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TSH58p_15935 df369438b309e2e1e9ebecc59fdc2c08 430 Gene3D G3DSA:3.90.170.10 266 430 7.5E-68 T 14-10-2018 TSH58p_15935 df369438b309e2e1e9ebecc59fdc2c08 430 SMART SM00788 3 423 3.2E-282 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TSH58p_15935 df369438b309e2e1e9ebecc59fdc2c08 430 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 14-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TSH58p_15935 df369438b309e2e1e9ebecc59fdc2c08 430 Gene3D G3DSA:3.40.440.10 6 258 1.8E-90 T 14-10-2018 TSH58p_10835 e38b5e770f111b1de110726c09d6dd13 194 SMART SM00855 3 149 5.7E-17 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TSH58p_10835 e38b5e770f111b1de110726c09d6dd13 194 SUPERFAMILY SSF53254 1 184 1.54E-37 T 14-10-2018 IPR029033 Histidine phosphatase superfamily TSH58p_10835 e38b5e770f111b1de110726c09d6dd13 194 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 188 9.6E-33 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TSH58p_10835 e38b5e770f111b1de110726c09d6dd13 194 Gene3D G3DSA:3.40.50.1240 1 184 3.9E-35 T 14-10-2018 IPR029033 Histidine phosphatase superfamily TSH58p_10835 e38b5e770f111b1de110726c09d6dd13 194 PIRSF PIRSF000709 3 157 1.1E-6 T 14-10-2018 TSH58p_01090 e5d8022fcc64e7a62ff0eb41bfd273dc 145 SUPERFAMILY SSF46626 1 132 6.45E-15 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_01090 e5d8022fcc64e7a62ff0eb41bfd273dc 145 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 50 126 1.5E-7 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_01090 e5d8022fcc64e7a62ff0eb41bfd273dc 145 Gene3D G3DSA:1.10.760.10 22 134 1.2E-11 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_06550 f9b4d8a370883da1d00099fdfd4849bc 62 Pfam PF09838 Uncharacterized protein conserved in bacteria (DUF2065) 4 59 2.3E-20 T 14-10-2018 IPR019201 Protein of unknown function DUF2065 TSH58p_01975 a8b2405dbbdb94878f74b21bbf2dea13 293 Pfam PF00535 Glycosyl transferase family 2 6 162 2.6E-18 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_01975 a8b2405dbbdb94878f74b21bbf2dea13 293 Gene3D G3DSA:3.90.550.10 1 220 1.9E-32 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_01975 a8b2405dbbdb94878f74b21bbf2dea13 293 SUPERFAMILY SSF53448 2 226 4.84E-32 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_26555 bafca735f8bfe517b9cab967c8b23143 140 Gene3D G3DSA:3.10.180.10 3 134 1.6E-34 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSH58p_26555 bafca735f8bfe517b9cab967c8b23143 140 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 124 9.9E-8 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TSH58p_26555 bafca735f8bfe517b9cab967c8b23143 140 SUPERFAMILY SSF54593 4 128 7.84E-23 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSH58p_23280 5224bbf70bdb5c6d873f37f93bb9f19c 195 Pfam PF03350 Uncharacterized protein family, UPF0114 38 154 1.4E-35 T 14-10-2018 IPR005134 Uncharacterised protein family UPF0114 TSH58p_23280 5224bbf70bdb5c6d873f37f93bb9f19c 195 TIGRFAM TIGR00645 HI0507: TIGR00645 family protein 31 194 3.9E-56 T 14-10-2018 IPR020761 Uncharacterised protein family UPF0114, bacteria TSH58p_23280 5224bbf70bdb5c6d873f37f93bb9f19c 195 Hamap MF_00143 UPF0114 protein YqhA [yqhA]. 26 195 69.717 T 14-10-2018 IPR020761 Uncharacterised protein family UPF0114, bacteria TSH58p_17020 21e66a7a4f8e7ef369b49c8e587bb222 327 Gene3D G3DSA:3.30.2130.10 200 325 1.3E-42 T 14-10-2018 TSH58p_17020 21e66a7a4f8e7ef369b49c8e587bb222 327 Pfam PF13840 ACT domain 257 318 2.1E-21 T 14-10-2018 IPR027795 CASTOR, ACT domain TSH58p_17020 21e66a7a4f8e7ef369b49c8e587bb222 327 SUPERFAMILY SSF55021 202 258 9.15E-10 T 14-10-2018 TSH58p_17020 21e66a7a4f8e7ef369b49c8e587bb222 327 SUPERFAMILY SSF48371 44 185 6.62E-7 T 14-10-2018 IPR016024 Armadillo-type fold TSH58p_17020 21e66a7a4f8e7ef369b49c8e587bb222 327 SUPERFAMILY SSF55021 260 320 2.84E-16 T 14-10-2018 TSH58p_17020 21e66a7a4f8e7ef369b49c8e587bb222 327 Gene3D G3DSA:1.25.10.10 23 185 8.7E-8 T 14-10-2018 IPR011989 Armadillo-like helical TSH58p_09555 14f710477fe81a070b868234468bd245 305 Pfam PF01522 Polysaccharide deacetylase 76 164 3.4E-11 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 TSH58p_09555 14f710477fe81a070b868234468bd245 305 SUPERFAMILY SSF88713 4 301 1.51E-94 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TSH58p_09555 14f710477fe81a070b868234468bd245 305 Gene3D G3DSA:3.20.20.370 1 305 8.9E-102 T 14-10-2018 TSH58p_09555 14f710477fe81a070b868234468bd245 305 TIGRFAM TIGR03212 uraD_N-term-dom: putative urate catabolism protein 5 301 3.6E-170 T 14-10-2018 IPR017625 PuuE allantoinase/chitin deacetylase 1 TSH58p_12080 a8c85ed0ff1efc7caa4263aa24711edb 151 Pfam PF03100 CcmE 3 128 5.6E-43 T 14-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 TSH58p_12080 a8c85ed0ff1efc7caa4263aa24711edb 151 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 1 138 31.372 T 14-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 TSH58p_12080 a8c85ed0ff1efc7caa4263aa24711edb 151 SUPERFAMILY SSF82093 29 134 7.06E-37 T 14-10-2018 IPR036127 CcmE-like superfamily GO:0005886|GO:0017003|GO:0017004 TSH58p_12080 a8c85ed0ff1efc7caa4263aa24711edb 151 Gene3D G3DSA:2.40.50.140 29 134 1.9E-36 T 14-10-2018 TSH58p_03240 e8101724b5cc93da2320d02798463b14 229 Gene3D G3DSA:3.40.50.1820 4 227 2.1E-44 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_03240 e8101724b5cc93da2320d02798463b14 229 SUPERFAMILY SSF53474 8 224 1.37E-29 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_03240 e8101724b5cc93da2320d02798463b14 229 Pfam PF12697 Alpha/beta hydrolase family 8 220 4.1E-20 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_24080 ab27b81d60523783f65853863d33f78a 357 PIRSF PIRSF026782 1 355 3.5E-125 T 14-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 TSH58p_24080 ab27b81d60523783f65853863d33f78a 357 Pfam PF01888 CbiD 1 261 2.3E-87 T 14-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 TSH58p_24080 ab27b81d60523783f65853863d33f78a 357 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 1 352 27.943 T 14-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 TSH58p_24080 ab27b81d60523783f65853863d33f78a 357 Gene3D G3DSA:3.30.2110.10 3 176 2.9E-49 T 14-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 TSH58p_24080 ab27b81d60523783f65853863d33f78a 357 SUPERFAMILY SSF111342 1 278 2.35E-81 T 14-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 TSH58p_06475 e415705bd0d5549bd0abf1542e818764 591 Pfam PF12729 Four helix bundle sensory module for signal transduction 31 175 7.3E-7 T 14-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain TSH58p_06475 e415705bd0d5549bd0abf1542e818764 591 Gene3D G3DSA:1.20.1480.50 200 298 2.7E-10 T 14-10-2018 TSH58p_06475 e415705bd0d5549bd0abf1542e818764 591 SUPERFAMILY SSF58104 267 584 1.27E-55 T 14-10-2018 TSH58p_06475 e415705bd0d5549bd0abf1542e818764 591 Gene3D G3DSA:1.10.287.950 299 589 8.8E-50 T 14-10-2018 TSH58p_06475 e415705bd0d5549bd0abf1542e818764 591 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 397 556 2.0E-25 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_06475 e415705bd0d5549bd0abf1542e818764 591 SMART SM00283 331 585 2.6E-34 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_06475 e415705bd0d5549bd0abf1542e818764 591 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 506 535 5.2E-18 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_06475 e415705bd0d5549bd0abf1542e818764 591 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 32 57 5.2E-18 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_06475 e415705bd0d5549bd0abf1542e818764 591 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 429 456 5.2E-18 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_06475 e415705bd0d5549bd0abf1542e818764 591 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 458 487 5.2E-18 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_13725 2e2d4f3d179d39c9ed7fafabc67ff69a 287 SUPERFAMILY SSF46626 32 146 3.64E-21 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_13725 2e2d4f3d179d39c9ed7fafabc67ff69a 287 Gene3D G3DSA:1.10.760.10 7 148 9.5E-12 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_13725 2e2d4f3d179d39c9ed7fafabc67ff69a 287 Gene3D G3DSA:1.10.760.10 168 286 2.8E-6 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_13725 2e2d4f3d179d39c9ed7fafabc67ff69a 287 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 33 136 1.3E-4 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_13725 2e2d4f3d179d39c9ed7fafabc67ff69a 287 SUPERFAMILY SSF46626 173 286 8.21E-15 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_19965 ea0fd949a1fd226dfd79019094f36198 448 SUPERFAMILY SSF53850 28 328 1.09E-52 T 14-10-2018 TSH58p_19965 ea0fd949a1fd226dfd79019094f36198 448 Gene3D G3DSA:3.40.190.10 136 252 4.9E-54 T 14-10-2018 TSH58p_19965 ea0fd949a1fd226dfd79019094f36198 448 Gene3D G3DSA:3.40.190.10 35 303 4.9E-54 T 14-10-2018 TSH58p_19965 ea0fd949a1fd226dfd79019094f36198 448 Pfam PF13343 Bacterial extracellular solute-binding protein 81 314 4.1E-32 T 14-10-2018 TSH58p_29770 ec1ec8f2426230aafa2852baf255ee95 1114 Pfam PF09899 Putative amidoligase enzyme (DUF2126) 276 1112 0.0 T 14-10-2018 IPR018667 Domain of unknown function DUF2126 TSH58p_29770 ec1ec8f2426230aafa2852baf255ee95 1114 Gene3D G3DSA:3.10.620.30 96 282 3.4E-26 T 14-10-2018 TSH58p_29770 ec1ec8f2426230aafa2852baf255ee95 1114 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 6 84 6.6E-26 T 14-10-2018 IPR013589 Bacterial transglutaminase-like, N-terminal TSH58p_29770 ec1ec8f2426230aafa2852baf255ee95 1114 SMART SM00460 172 248 1.2E-20 T 14-10-2018 IPR002931 Transglutaminase-like TSH58p_29770 ec1ec8f2426230aafa2852baf255ee95 1114 SUPERFAMILY SSF54001 8 337 1.96E-67 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily TSH58p_29770 ec1ec8f2426230aafa2852baf255ee95 1114 Pfam PF01841 Transglutaminase-like superfamily 137 246 3.2E-17 T 14-10-2018 IPR002931 Transglutaminase-like TSH58p_24965 956a3da366cad482370f9be33c05bdb2 286 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 18 276 4.9E-99 T 14-10-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 TSH58p_24965 956a3da366cad482370f9be33c05bdb2 286 SUPERFAMILY SSF161098 17 269 2.09E-55 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_24965 956a3da366cad482370f9be33c05bdb2 286 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 19 277 2.7E-126 T 14-10-2018 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 TSH58p_24965 956a3da366cad482370f9be33c05bdb2 286 Gene3D G3DSA:1.10.3720.10 21 276 4.4E-63 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_24965 956a3da366cad482370f9be33c05bdb2 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 268 7.5E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_17860 6c02e6166516f730ed972a450be9d459 289 Pfam PF00535 Glycosyl transferase family 2 7 113 1.8E-33 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_17860 6c02e6166516f730ed972a450be9d459 289 SUPERFAMILY SSF53448 4 207 2.89E-56 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_17860 6c02e6166516f730ed972a450be9d459 289 Gene3D G3DSA:3.90.550.10 1 211 2.5E-57 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_32615 e64aaf127dd61a7db9722fb338ad8d4f 805 SMART SM00965 60 110 4.3E-10 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 TSH58p_32615 e64aaf127dd61a7db9722fb338ad8d4f 805 Pfam PF00593 TonB dependent receptor 348 803 5.8E-54 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel TSH58p_32615 e64aaf127dd61a7db9722fb338ad8d4f 805 Pfam PF07660 Secretin and TonB N terminus short domain 60 109 7.7E-8 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 TSH58p_32615 e64aaf127dd61a7db9722fb338ad8d4f 805 Gene3D G3DSA:2.40.170.20 262 805 2.7E-125 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily TSH58p_32615 e64aaf127dd61a7db9722fb338ad8d4f 805 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 151 804 1.6E-101 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 TSH58p_32615 e64aaf127dd61a7db9722fb338ad8d4f 805 Pfam PF07715 TonB-dependent Receptor Plug Domain 149 251 7.5E-20 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain TSH58p_32615 e64aaf127dd61a7db9722fb338ad8d4f 805 Gene3D G3DSA:2.170.130.10 132 261 1.2E-29 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily TSH58p_32615 e64aaf127dd61a7db9722fb338ad8d4f 805 Gene3D G3DSA:3.55.50.30 36 117 5.5E-24 T 14-10-2018 TSH58p_32615 e64aaf127dd61a7db9722fb338ad8d4f 805 SUPERFAMILY SSF56935 144 805 6.6E-121 T 14-10-2018 TSH58p_13910 bd0462be4aedeca91856e1db23ac9764 269 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_13910 bd0462be4aedeca91856e1db23ac9764 269 Gene3D G3DSA:3.40.50.300 30 256 1.4E-54 T 14-10-2018 TSH58p_13910 bd0462be4aedeca91856e1db23ac9764 269 SMART SM00382 58 229 2.7E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_13910 bd0462be4aedeca91856e1db23ac9764 269 Pfam PF00005 ABC transporter 50 179 9.2E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_13910 bd0462be4aedeca91856e1db23ac9764 269 SUPERFAMILY SSF52540 41 235 7.29E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_02715 49796328df7299e304f142f19415417c 347 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 47 300 9.3E-69 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 TSH58p_02715 49796328df7299e304f142f19415417c 347 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 53 313 3.5E-70 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 TSH58p_02715 49796328df7299e304f142f19415417c 347 PIRSF PIRSF006470 13 339 1.2E-69 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 TSH58p_02715 49796328df7299e304f142f19415417c 347 Gene3D G3DSA:3.40.190.170 39 347 5.7E-105 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily TSH58p_32515 01abfd483958dd1b74c35bf760dc7179 252 SMART SM00382 29 222 1.9E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_32515 01abfd483958dd1b74c35bf760dc7179 252 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 223 245 6.8E-7 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSH58p_32515 01abfd483958dd1b74c35bf760dc7179 252 SUPERFAMILY SSF52540 4 246 2.42E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_32515 01abfd483958dd1b74c35bf760dc7179 252 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_32515 01abfd483958dd1b74c35bf760dc7179 252 Pfam PF00005 ABC transporter 22 175 6.1E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_32515 01abfd483958dd1b74c35bf760dc7179 252 Gene3D G3DSA:3.40.50.300 2 249 1.0E-58 T 14-10-2018 TSH58p_01515 f06f82c2bfd25cb347c91debe2704030 251 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_01515 f06f82c2bfd25cb347c91debe2704030 251 PIRSF PIRSF039085 1 251 2.7E-115 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 TSH58p_01515 f06f82c2bfd25cb347c91debe2704030 251 Gene3D G3DSA:3.40.50.300 1 250 3.5E-79 T 14-10-2018 TSH58p_01515 f06f82c2bfd25cb347c91debe2704030 251 Pfam PF00005 ABC transporter 17 175 1.4E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_01515 f06f82c2bfd25cb347c91debe2704030 251 SMART SM00382 26 223 1.0E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_01515 f06f82c2bfd25cb347c91debe2704030 251 SUPERFAMILY SSF52540 1 245 5.09E-76 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_24600 31b22eb35fc9cf997fd575d972cc2f41 305 Pfam PF03466 LysR substrate binding domain 88 292 1.4E-41 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_24600 31b22eb35fc9cf997fd575d972cc2f41 305 Gene3D G3DSA:3.40.190.10 91 288 4.7E-64 T 14-10-2018 TSH58p_24600 31b22eb35fc9cf997fd575d972cc2f41 305 Gene3D G3DSA:1.10.10.10 1 90 1.5E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_24600 31b22eb35fc9cf997fd575d972cc2f41 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.1E-22 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_24600 31b22eb35fc9cf997fd575d972cc2f41 305 Gene3D G3DSA:3.40.190.10 166 271 4.7E-64 T 14-10-2018 TSH58p_24600 31b22eb35fc9cf997fd575d972cc2f41 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.3E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_24600 31b22eb35fc9cf997fd575d972cc2f41 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.3E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_24600 31b22eb35fc9cf997fd575d972cc2f41 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.3E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_24600 31b22eb35fc9cf997fd575d972cc2f41 305 SUPERFAMILY SSF53850 88 296 1.09E-36 T 14-10-2018 TSH58p_24600 31b22eb35fc9cf997fd575d972cc2f41 305 SUPERFAMILY SSF46785 1 83 7.71E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_11285 7f44bf83ee02bbec85597f3332a12ca0 488 SUPERFAMILY SSF53335 227 434 8.92E-37 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_11285 7f44bf83ee02bbec85597f3332a12ca0 488 Gene3D G3DSA:3.40.50.150 229 473 2.5E-44 T 14-10-2018 TSH58p_11285 7f44bf83ee02bbec85597f3332a12ca0 488 Pfam PF08241 Methyltransferase domain 288 387 6.0E-6 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TSH58p_12635 b4b6821073de6bb9a78b1d069da1bc90 447 Pfam PF13458 Periplasmic binding protein 39 407 5.6E-75 T 14-10-2018 IPR028081 Leucine-binding protein domain TSH58p_12635 b4b6821073de6bb9a78b1d069da1bc90 447 SUPERFAMILY SSF53822 43 411 3.33E-47 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_12635 b4b6821073de6bb9a78b1d069da1bc90 447 Gene3D G3DSA:3.40.50.2300 47 369 2.8E-74 T 14-10-2018 TSH58p_12635 b4b6821073de6bb9a78b1d069da1bc90 447 Gene3D G3DSA:3.40.50.2300 159 301 2.8E-74 T 14-10-2018 TSH58p_19490 7f66615a9768c81c923771a6fd783654 378 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 255 273 8.0E-13 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_19490 7f66615a9768c81c923771a6fd783654 378 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 48 64 8.0E-13 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_19490 7f66615a9768c81c923771a6fd783654 378 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 26 42 8.0E-13 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_19490 7f66615a9768c81c923771a6fd783654 378 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 67 85 8.0E-13 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_19490 7f66615a9768c81c923771a6fd783654 378 Pfam PF13458 Periplasmic binding protein 25 364 1.5E-81 T 14-10-2018 IPR028081 Leucine-binding protein domain TSH58p_19490 7f66615a9768c81c923771a6fd783654 378 Gene3D G3DSA:3.40.50.2300 145 273 1.3E-101 T 14-10-2018 TSH58p_19490 7f66615a9768c81c923771a6fd783654 378 SUPERFAMILY SSF53822 24 369 4.71E-100 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_19490 7f66615a9768c81c923771a6fd783654 378 Gene3D G3DSA:3.40.50.2300 27 341 1.3E-101 T 14-10-2018 TSH58p_29170 96adb2adfaebfe1920b8ded9ac163c2d 183 Gene3D G3DSA:3.40.630.30 1 168 1.1E-31 T 14-10-2018 TSH58p_29170 96adb2adfaebfe1920b8ded9ac163c2d 183 SUPERFAMILY SSF55729 3 161 4.75E-24 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_29170 96adb2adfaebfe1920b8ded9ac163c2d 183 Pfam PF13302 Acetyltransferase (GNAT) domain 3 130 5.4E-9 T 14-10-2018 IPR000182 GNAT domain TSH58p_16755 975418ec6c7f7852e73be73d93cfcaa6 205 Pfam PF05494 MlaC protein 40 199 4.4E-47 T 14-10-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC TSH58p_16755 975418ec6c7f7852e73be73d93cfcaa6 205 PIRSF PIRSF004649 2 205 8.2E-39 T 14-10-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC TSH58p_16755 975418ec6c7f7852e73be73d93cfcaa6 205 Gene3D G3DSA:3.10.450.710 31 204 1.2E-38 T 14-10-2018 TSH58p_01650 524b3ca80a0238a681abdb442f253e91 288 SUPERFAMILY SSF52540 19 258 8.56E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_01650 524b3ca80a0238a681abdb442f253e91 288 Pfam PF00005 ABC transporter 43 193 3.6E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_01650 524b3ca80a0238a681abdb442f253e91 288 Gene3D G3DSA:3.40.50.300 20 277 1.4E-71 T 14-10-2018 TSH58p_01650 524b3ca80a0238a681abdb442f253e91 288 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_01650 524b3ca80a0238a681abdb442f253e91 288 SMART SM00382 52 238 4.3E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_02520 00fdaffeb50f401dd6e216e4d1067a07 484 PIRSF PIRSF006247 1 484 1.2E-169 T 14-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 TSH58p_02520 00fdaffeb50f401dd6e216e4d1067a07 484 Pfam PF02386 Cation transport protein 40 478 1.9E-54 T 14-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 TSH58p_06460 3b85a0d4586dceaeedc62fea5e74f2ac 332 SUPERFAMILY SSF53822 43 274 2.39E-16 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_06460 3b85a0d4586dceaeedc62fea5e74f2ac 332 Gene3D G3DSA:3.40.50.2300 133 325 4.2E-97 T 14-10-2018 TSH58p_06460 3b85a0d4586dceaeedc62fea5e74f2ac 332 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 34 322 5.1E-61 T 14-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 TSH58p_06460 3b85a0d4586dceaeedc62fea5e74f2ac 332 Gene3D G3DSA:3.40.50.2300 34 289 4.2E-97 T 14-10-2018 TSH58p_16130 25b468fd4445e0f0f890272f4fb0db2a 326 Gene3D G3DSA:3.40.50.11270 17 101 4.6E-108 T 14-10-2018 TSH58p_16130 25b468fd4445e0f0f890272f4fb0db2a 326 Gene3D G3DSA:3.40.1010.20 102 199 4.6E-108 T 14-10-2018 TSH58p_16130 25b468fd4445e0f0f890272f4fb0db2a 326 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 6 290 37.044 T 14-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 TSH58p_16130 25b468fd4445e0f0f890272f4fb0db2a 326 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 7 286 4.4E-99 T 14-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 TSH58p_16130 25b468fd4445e0f0f890272f4fb0db2a 326 Gene3D G3DSA:3.40.1010.20 12 284 4.6E-108 T 14-10-2018 TSH58p_16130 25b468fd4445e0f0f890272f4fb0db2a 326 Pfam PF02401 LytB protein 8 285 7.6E-89 T 14-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 TSH58p_22550 29cb7aa7b10649d1c2f16ee87d8ce7e9 181 Pfam PF13643 Domain of unknown function (DUF4145) 32 130 7.0E-17 T 14-10-2018 IPR025285 Domain of unknown function DUF4145 TSH58p_04550 5b94c85901849abef34b5aee6fc22948 286 Pfam PF14326 Domain of unknown function (DUF4384) 177 244 4.7E-9 T 14-10-2018 IPR025493 Domain of unknown function DUF4384 TSH58p_06725 44b781942cda930c1c61feaba82eff5e 169 SUPERFAMILY SSF88659 96 157 5.79E-18 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSH58p_06725 44b781942cda930c1c61feaba82eff5e 169 Gene3D G3DSA:1.10.10.10 95 161 4.9E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_06725 44b781942cda930c1c61feaba82eff5e 169 SUPERFAMILY SSF88946 4 85 1.65E-19 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_06725 44b781942cda930c1c61feaba82eff5e 169 Pfam PF04542 Sigma-70 region 2 11 74 9.7E-15 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_06725 44b781942cda930c1c61feaba82eff5e 169 Gene3D G3DSA:1.10.1740.10 2 66 3.4E-21 T 14-10-2018 TSH58p_06725 44b781942cda930c1c61feaba82eff5e 169 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 157 8.4E-28 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TSH58p_06725 44b781942cda930c1c61feaba82eff5e 169 Pfam PF08281 Sigma-70, region 4 101 152 2.2E-18 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_29385 4b46239d9c8db2dce0ba532b7a92839e 329 Gene3D G3DSA:3.40.50.300 2 320 3.2E-94 T 14-10-2018 TSH58p_29385 4b46239d9c8db2dce0ba532b7a92839e 329 SMART SM00382 32 231 3.2E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_29385 4b46239d9c8db2dce0ba532b7a92839e 329 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 315 4.9E-22 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_29385 4b46239d9c8db2dce0ba532b7a92839e 329 Pfam PF00005 ABC transporter 24 181 4.9E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_29385 4b46239d9c8db2dce0ba532b7a92839e 329 SUPERFAMILY SSF52540 3 252 2.78E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_29385 4b46239d9c8db2dce0ba532b7a92839e 329 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 297 4.4E-18 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_04695 ce7ad3314999862c7f85c5807df40bc0 175 Gene3D G3DSA:2.20.25.120 47 80 3.6E-56 T 14-10-2018 TSH58p_04695 ce7ad3314999862c7f85c5807df40bc0 175 SUPERFAMILY SSF52540 1 163 1.13E-27 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_04695 ce7ad3314999862c7f85c5807df40bc0 175 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 4 136 3.8E-52 T 14-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 TSH58p_04695 ce7ad3314999862c7f85c5807df40bc0 175 Gene3D G3DSA:3.40.50.300 5 159 3.6E-56 T 14-10-2018 TSH58p_04695 ce7ad3314999862c7f85c5807df40bc0 175 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 4 160 5.8E-47 T 14-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 TSH58p_28335 b56c8213288fb8bf3a95144347172baa 631 Gene3D G3DSA:3.40.50.300 1 258 6.6E-58 T 14-10-2018 TSH58p_28335 b56c8213288fb8bf3a95144347172baa 631 Gene3D G3DSA:3.40.50.300 272 535 3.9E-55 T 14-10-2018 TSH58p_28335 b56c8213288fb8bf3a95144347172baa 631 Pfam PF00005 ABC transporter 325 456 2.0E-20 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_28335 b56c8213288fb8bf3a95144347172baa 631 SUPERFAMILY SSF52540 289 510 1.45E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_28335 b56c8213288fb8bf3a95144347172baa 631 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_28335 b56c8213288fb8bf3a95144347172baa 631 SUPERFAMILY SSF52540 2 236 4.78E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_28335 b56c8213288fb8bf3a95144347172baa 631 Pfam PF00005 ABC transporter 21 175 1.0E-22 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_28335 b56c8213288fb8bf3a95144347172baa 631 Pfam PF16326 ABC transporter C-terminal domain 557 617 2.8E-8 T 14-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 TSH58p_28335 b56c8213288fb8bf3a95144347172baa 631 Pfam PF12848 ABC transporter 214 293 1.7E-26 T 14-10-2018 IPR032781 ABC-transporter extension domain TSH58p_28335 b56c8213288fb8bf3a95144347172baa 631 ProSitePatterns PS00211 ABC transporters family signature. 428 442 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_28335 b56c8213288fb8bf3a95144347172baa 631 SMART SM00382 26 220 3.9E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_28335 b56c8213288fb8bf3a95144347172baa 631 SMART SM00382 334 501 4.7E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_06710 e73324f13748b9044a9e321895561b50 556 SMART SM00028 4 37 81.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_06710 e73324f13748b9044a9e321895561b50 556 SMART SM00028 173 206 97.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_06710 e73324f13748b9044a9e321895561b50 556 SMART SM00028 38 71 21.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_06710 e73324f13748b9044a9e321895561b50 556 SMART SM00028 106 139 51.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_06710 e73324f13748b9044a9e321895561b50 556 SMART SM00028 207 240 110.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_06710 e73324f13748b9044a9e321895561b50 556 SUPERFAMILY SSF53756 292 529 6.59E-18 T 14-10-2018 TSH58p_06710 e73324f13748b9044a9e321895561b50 556 Gene3D G3DSA:3.40.50.2000 404 527 2.0E-5 T 14-10-2018 TSH58p_06710 e73324f13748b9044a9e321895561b50 556 Pfam PF13432 Tetratricopeptide repeat 83 139 0.014 T 14-10-2018 TSH58p_06710 e73324f13748b9044a9e321895561b50 556 Pfam PF13432 Tetratricopeptide repeat 9 72 9.1E-7 T 14-10-2018 TSH58p_06710 e73324f13748b9044a9e321895561b50 556 SUPERFAMILY SSF48452 15 269 3.65E-22 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_06710 e73324f13748b9044a9e321895561b50 556 Gene3D G3DSA:1.25.40.10 108 168 3.2E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_06710 e73324f13748b9044a9e321895561b50 556 Gene3D G3DSA:1.25.40.10 7 107 8.4E-15 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_06710 e73324f13748b9044a9e321895561b50 556 Gene3D G3DSA:1.25.40.10 169 281 9.8E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_26915 58e9e5b1c6d6227966b27c1bd63e582a 277 Pfam PF13714 Phosphoenolpyruvate phosphomutase 12 249 9.5E-68 T 14-10-2018 TSH58p_26915 58e9e5b1c6d6227966b27c1bd63e582a 277 Gene3D G3DSA:3.20.20.60 2 275 8.9E-61 T 14-10-2018 TSH58p_26915 58e9e5b1c6d6227966b27c1bd63e582a 277 SUPERFAMILY SSF51621 8 274 1.17E-58 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSH58p_22770 309832ae69ff34b16acec242845105da 80 Pfam PF12728 Helix-turn-helix domain 25 67 2.4E-6 T 14-10-2018 TSH58p_05595 60d2ab25c3d7435697a65e97279a98ae 251 Pfam PF00121 Triosephosphate isomerase 6 246 3.2E-80 T 14-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_05595 60d2ab25c3d7435697a65e97279a98ae 251 Gene3D G3DSA:3.20.20.70 1 251 1.7E-94 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_05595 60d2ab25c3d7435697a65e97279a98ae 251 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 4 249 56.34 T 14-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_05595 60d2ab25c3d7435697a65e97279a98ae 251 ProSitePatterns PS00171 Triosephosphate isomerase active site. 167 177 - T 14-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_05595 60d2ab25c3d7435697a65e97279a98ae 251 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 7 241 2.7E-55 T 14-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_05595 60d2ab25c3d7435697a65e97279a98ae 251 SUPERFAMILY SSF51351 3 247 1.02E-87 T 14-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_08600 9fac9f3da08086fab6c361e546e3cf0f 98 Gene3D G3DSA:3.30.460.10 10 96 3.4E-24 T 14-10-2018 TSH58p_08600 9fac9f3da08086fab6c361e546e3cf0f 98 SUPERFAMILY SSF81301 14 96 8.92E-20 T 14-10-2018 TSH58p_08600 9fac9f3da08086fab6c361e546e3cf0f 98 Pfam PF01909 Nucleotidyltransferase domain 17 97 1.1E-12 T 14-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TSH58p_19820 589b3d528edbe802fcc94ea366e3017e 169 Pfam PF11162 Protein of unknown function (DUF2946) 50 161 2.6E-6 T 14-10-2018 IPR021333 Protein of unknown function DUF2946 TSH58p_06455 fcb2808d7d04f45ae455c11b8d98f162 511 SUPERFAMILY SSF52540 242 495 1.18E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_06455 fcb2808d7d04f45ae455c11b8d98f162 511 Pfam PF00005 ABC transporter 25 171 6.1E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_06455 fcb2808d7d04f45ae455c11b8d98f162 511 ProSitePatterns PS00211 ABC transporters family signature. 409 423 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_06455 fcb2808d7d04f45ae455c11b8d98f162 511 Pfam PF00005 ABC transporter 277 436 1.3E-14 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_06455 fcb2808d7d04f45ae455c11b8d98f162 511 Gene3D G3DSA:3.40.50.300 2 245 3.3E-58 T 14-10-2018 TSH58p_06455 fcb2808d7d04f45ae455c11b8d98f162 511 SUPERFAMILY SSF52540 6 225 2.13E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_06455 fcb2808d7d04f45ae455c11b8d98f162 511 Gene3D G3DSA:3.40.50.300 254 504 8.9E-37 T 14-10-2018 TSH58p_06455 fcb2808d7d04f45ae455c11b8d98f162 511 SMART SM00382 32 220 1.9E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_06455 fcb2808d7d04f45ae455c11b8d98f162 511 SMART SM00382 285 485 0.43 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_03565 41abfbb00db15643b0ad31ab9f48bdc6 148 PRINTS PR01996 Phage major tail protein 1 family signature 28 57 2.8E-10 T 14-10-2018 IPR022344 Gene transfer agent, major tail protein TSH58p_03565 41abfbb00db15643b0ad31ab9f48bdc6 148 PRINTS PR01996 Phage major tail protein 1 family signature 7 19 2.8E-10 T 14-10-2018 IPR022344 Gene transfer agent, major tail protein TSH58p_03565 41abfbb00db15643b0ad31ab9f48bdc6 148 PRINTS PR01996 Phage major tail protein 1 family signature 57 86 2.8E-10 T 14-10-2018 IPR022344 Gene transfer agent, major tail protein TSH58p_03565 41abfbb00db15643b0ad31ab9f48bdc6 148 Pfam PF06199 Phage tail tube protein 10 143 1.2E-19 T 14-10-2018 IPR011855 Phage major tail protein TP901-1 TSH58p_05125 a1a70ba5f410b8b38f134c0d2b3de03c 420 Pfam PF05161 MOFRL family 308 413 1.2E-36 T 14-10-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 TSH58p_05125 a1a70ba5f410b8b38f134c0d2b3de03c 420 Gene3D G3DSA:3.40.1480.10 253 414 4.3E-149 T 14-10-2018 IPR037035 Glycerate kinase-like, C-terminal domain superfamily TSH58p_05125 a1a70ba5f410b8b38f134c0d2b3de03c 420 Gene3D G3DSA:3.40.50.10180 36 252 4.3E-149 T 14-10-2018 IPR038614 Glycerate kinase, N-terminal domain superfamily Reactome: R-HSA-70350 TSH58p_05125 a1a70ba5f410b8b38f134c0d2b3de03c 420 Pfam PF13660 Domain of unknown function (DUF4147) 10 228 2.6E-87 T 14-10-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 TSH58p_05125 a1a70ba5f410b8b38f134c0d2b3de03c 420 SUPERFAMILY SSF82544 4 419 1.06E-156 T 14-10-2018 TSH58p_30740 af02b5113e606815e353bdc9be709de2 476 ProSitePatterns PS00571 Amidases signature. 150 181 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 TSH58p_30740 af02b5113e606815e353bdc9be709de2 476 Gene3D G3DSA:3.90.1300.10 5 476 7.0E-144 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_30740 af02b5113e606815e353bdc9be709de2 476 Pfam PF01425 Amidase 28 455 5.3E-94 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_30740 af02b5113e606815e353bdc9be709de2 476 SUPERFAMILY SSF75304 5 464 1.13E-121 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_32560 8352c6da9da6f5e2f7bb76501a74774f 291 Gene3D G3DSA:3.20.20.140 3 291 1.8E-88 T 14-10-2018 TSH58p_32560 8352c6da9da6f5e2f7bb76501a74774f 291 SUPERFAMILY SSF51556 20 288 8.67E-82 T 14-10-2018 IPR032466 Metal-dependent hydrolase TSH58p_32560 8352c6da9da6f5e2f7bb76501a74774f 291 Pfam PF04909 Amidohydrolase 24 288 2.0E-47 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TSH58p_08150 8b9f1bb4df37a68e57a344f91f0ce1df 231 SUPERFAMILY SSF53271 17 224 8.78E-46 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like TSH58p_08150 8b9f1bb4df37a68e57a344f91f0ce1df 231 Pfam PF00156 Phosphoribosyl transferase domain 59 164 7.2E-13 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TSH58p_08150 8b9f1bb4df37a68e57a344f91f0ce1df 231 Gene3D G3DSA:3.40.50.2020 5 231 6.0E-66 T 14-10-2018 TSH58p_08150 8b9f1bb4df37a68e57a344f91f0ce1df 231 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 231 28.63 T 14-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSH58p_23460 26961b99844e328a20528f094a24f316 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 248 7.4E-51 T 14-10-2018 TSH58p_23460 26961b99844e328a20528f094a24f316 251 SUPERFAMILY SSF51735 2 249 1.51E-67 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_23460 26961b99844e328a20528f094a24f316 251 Gene3D G3DSA:3.40.50.720 1 249 2.3E-70 T 14-10-2018 TSH58p_23460 26961b99844e328a20528f094a24f316 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 1.1E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_23460 26961b99844e328a20528f094a24f316 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 1.1E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_23460 26961b99844e328a20528f094a24f316 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 1.1E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_23460 26961b99844e328a20528f094a24f316 251 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 76 93 2.4E-52 T 14-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 TSH58p_23460 26961b99844e328a20528f094a24f316 251 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 96 116 2.4E-52 T 14-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 TSH58p_23460 26961b99844e328a20528f094a24f316 251 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 13 30 2.4E-52 T 14-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 TSH58p_23460 26961b99844e328a20528f094a24f316 251 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 227 246 2.4E-52 T 14-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 TSH58p_23460 26961b99844e328a20528f094a24f316 251 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 162 185 2.4E-52 T 14-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 TSH58p_23460 26961b99844e328a20528f094a24f316 251 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 201 220 2.4E-52 T 14-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 TSH58p_23460 26961b99844e328a20528f094a24f316 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 169 0.0084 T 14-10-2018 TSH58p_23460 26961b99844e328a20528f094a24f316 251 TIGRFAM TIGR04316 dhbA_paeA: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 9 250 1.4E-96 T 14-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 TSH58p_23460 26961b99844e328a20528f094a24f316 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_22840 4890ab255e5bce319443a0b15a061b09 172 Pfam PF00583 Acetyltransferase (GNAT) family 35 155 3.0E-11 T 14-10-2018 IPR000182 GNAT domain TSH58p_22840 4890ab255e5bce319443a0b15a061b09 172 Gene3D G3DSA:3.40.630.30 79 172 2.7E-19 T 14-10-2018 TSH58p_22840 4890ab255e5bce319443a0b15a061b09 172 SUPERFAMILY SSF55729 9 158 1.72E-16 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_08100 a8b8a456fff2dda727645fd025830387 1239 SUPERFAMILY SSF75625 296 385 1.57E-13 T 14-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_08100 a8b8a456fff2dda727645fd025830387 1239 SUPERFAMILY SSF51998 197 916 2.2E-124 T 14-10-2018 TSH58p_08100 a8b8a456fff2dda727645fd025830387 1239 Pfam PF02867 Ribonucleotide reductase, barrel domain 803 905 3.7E-17 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSH58p_08100 a8b8a456fff2dda727645fd025830387 1239 Gene3D G3DSA:3.20.70.20 365 770 3.5E-97 T 14-10-2018 TSH58p_08100 a8b8a456fff2dda727645fd025830387 1239 Gene3D G3DSA:3.20.70.20 90 349 1.4E-54 T 14-10-2018 TSH58p_08100 a8b8a456fff2dda727645fd025830387 1239 Gene3D G3DSA:3.20.70.20 798 920 3.3E-29 T 14-10-2018 TSH58p_08100 a8b8a456fff2dda727645fd025830387 1239 Pfam PF02867 Ribonucleotide reductase, barrel domain 198 744 6.5E-105 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSH58p_08100 a8b8a456fff2dda727645fd025830387 1239 Pfam PF08471 Class II vitamin B12-dependent ribonucleotide reductase 31 147 6.5E-42 T 14-10-2018 IPR013678 Ribonucleotide reductase class II vitamin B12-dependent, N-terminal domain GO:0004748|GO:0050897|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSH58p_08100 a8b8a456fff2dda727645fd025830387 1239 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 132 746 3.6E-146 T 14-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSH58p_31110 e81742973c75f4c0ca2d5c4fb149fe63 337 Gene3D G3DSA:1.10.10.10 24 105 2.7E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_31110 e81742973c75f4c0ca2d5c4fb149fe63 337 SUPERFAMILY SSF46785 24 135 1.54E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_31110 e81742973c75f4c0ca2d5c4fb149fe63 337 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 53 63 9.1E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_31110 e81742973c75f4c0ca2d5c4fb149fe63 337 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 9.1E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_31110 e81742973c75f4c0ca2d5c4fb149fe63 337 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 63 74 9.1E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_31110 e81742973c75f4c0ca2d5c4fb149fe63 337 Gene3D G3DSA:3.40.190.10 116 300 5.4E-27 T 14-10-2018 TSH58p_31110 e81742973c75f4c0ca2d5c4fb149fe63 337 Gene3D G3DSA:3.40.190.10 187 291 5.4E-27 T 14-10-2018 TSH58p_31110 e81742973c75f4c0ca2d5c4fb149fe63 337 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 27 85 1.1E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_31110 e81742973c75f4c0ca2d5c4fb149fe63 337 SUPERFAMILY SSF53850 116 301 1.21E-25 T 14-10-2018 TSH58p_31110 e81742973c75f4c0ca2d5c4fb149fe63 337 Pfam PF03466 LysR substrate binding domain 116 301 2.4E-24 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_09015 d558ab8b23a7a1e4c1b3ed767f034d5c 155 PIRSF PIRSF005900 1 155 1.9E-48 T 14-10-2018 IPR002177 DNA-binding protein Dps TSH58p_09015 d558ab8b23a7a1e4c1b3ed767f034d5c 155 Gene3D G3DSA:1.20.1260.10 1 155 2.0E-60 T 14-10-2018 IPR012347 Ferritin-like TSH58p_09015 d558ab8b23a7a1e4c1b3ed767f034d5c 155 ProSitePatterns PS00819 Dps protein family signature 2. 63 77 - T 14-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 TSH58p_09015 d558ab8b23a7a1e4c1b3ed767f034d5c 155 SUPERFAMILY SSF47240 5 155 7.88E-51 T 14-10-2018 IPR009078 Ferritin-like superfamily TSH58p_09015 d558ab8b23a7a1e4c1b3ed767f034d5c 155 Pfam PF00210 Ferritin-like domain 17 155 7.6E-32 T 14-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 TSH58p_09015 d558ab8b23a7a1e4c1b3ed767f034d5c 155 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 37 53 2.0E-11 T 14-10-2018 IPR002177 DNA-binding protein Dps TSH58p_09015 d558ab8b23a7a1e4c1b3ed767f034d5c 155 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 61 77 2.0E-11 T 14-10-2018 IPR002177 DNA-binding protein Dps TSH58p_09015 d558ab8b23a7a1e4c1b3ed767f034d5c 155 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 132 150 2.0E-11 T 14-10-2018 IPR002177 DNA-binding protein Dps TSH58p_01025 073a2915455f5be2ea7fe161e3144b78 387 SUPERFAMILY SSF53901 11 233 8.65E-25 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_01025 073a2915455f5be2ea7fe161e3144b78 387 Gene3D G3DSA:3.40.47.10 1 387 6.3E-108 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_01025 073a2915455f5be2ea7fe161e3144b78 387 SUPERFAMILY SSF53901 235 377 6.61E-24 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_25930 a63d58714759f025d42ca4ce1f6bd23a 357 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 227 243 - T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TSH58p_25930 a63d58714759f025d42ca4ce1f6bd23a 357 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 5 356 3.1E-150 T 14-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 TSH58p_25930 a63d58714759f025d42ca4ce1f6bd23a 357 Pfam PF00472 RF-1 domain 211 320 3.6E-42 T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TSH58p_25930 a63d58714759f025d42ca4ce1f6bd23a 357 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 3 357 38.928 T 14-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 TSH58p_25930 a63d58714759f025d42ca4ce1f6bd23a 357 SMART SM00937 63 178 3.4E-55 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 TSH58p_25930 a63d58714759f025d42ca4ce1f6bd23a 357 Gene3D G3DSA:3.30.160.20 210 296 1.5E-97 T 14-10-2018 TSH58p_25930 a63d58714759f025d42ca4ce1f6bd23a 357 SUPERFAMILY SSF75620 12 353 2.62E-126 T 14-10-2018 TSH58p_25930 a63d58714759f025d42ca4ce1f6bd23a 357 Pfam PF03462 PCRF domain 12 203 7.9E-66 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 TSH58p_25930 a63d58714759f025d42ca4ce1f6bd23a 357 Gene3D G3DSA:3.30.70.1660 112 342 1.5E-97 T 14-10-2018 TSH58p_23425 a0af581a872d5e781b8801b92f9d6da4 640 Pfam PF07715 TonB-dependent Receptor Plug Domain 49 157 1.5E-23 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain TSH58p_23425 a0af581a872d5e781b8801b92f9d6da4 640 Gene3D G3DSA:2.170.130.10 30 162 2.2E-37 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily TSH58p_23425 a0af581a872d5e781b8801b92f9d6da4 640 Gene3D G3DSA:2.40.170.20 168 640 5.2E-116 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily TSH58p_23425 a0af581a872d5e781b8801b92f9d6da4 640 SUPERFAMILY SSF56935 21 640 4.58E-123 T 14-10-2018 TSH58p_23425 a0af581a872d5e781b8801b92f9d6da4 640 Pfam PF00593 TonB dependent receptor 245 639 3.2E-62 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel TSH58p_11075 95652967a8971c60159d2ec1e6ade79d 341 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 133 149 - T 14-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 TSH58p_11075 95652967a8971c60159d2ec1e6ade79d 341 Gene3D G3DSA:3.20.20.210 1 339 2.0E-124 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 TSH58p_11075 95652967a8971c60159d2ec1e6ade79d 341 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 1 337 2.2E-114 T 14-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 TSH58p_11075 95652967a8971c60159d2ec1e6ade79d 341 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 2 335 1.5E-121 T 14-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 TSH58p_11075 95652967a8971c60159d2ec1e6ade79d 341 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 2 338 45.731 T 14-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 TSH58p_11075 95652967a8971c60159d2ec1e6ade79d 341 SUPERFAMILY SSF51726 2 337 6.28E-101 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 TSH58p_03005 2426229eb15f4424d03d80cd6992240f 478 Gene3D G3DSA:3.20.20.140 54 429 2.6E-178 T 14-10-2018 TSH58p_03005 2426229eb15f4424d03d80cd6992240f 478 SUPERFAMILY SSF51338 3 66 1.73E-13 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_03005 2426229eb15f4424d03d80cd6992240f 478 SUPERFAMILY SSF51338 361 459 2.54E-38 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_03005 2426229eb15f4424d03d80cd6992240f 478 Gene3D G3DSA:2.30.40.10 4 458 2.6E-178 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_03005 2426229eb15f4424d03d80cd6992240f 478 SUPERFAMILY SSF51556 54 388 2.25E-104 T 14-10-2018 IPR032466 Metal-dependent hydrolase TSH58p_03005 2426229eb15f4424d03d80cd6992240f 478 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 6 460 5.3E-167 T 14-10-2018 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 TSH58p_03005 2426229eb15f4424d03d80cd6992240f 478 Pfam PF01979 Amidohydrolase family 50 441 4.0E-26 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TSH58p_13415 57208f43bf4bbc5eacf07bd1058a9909 220 SUPERFAMILY SSF47616 82 208 2.42E-14 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily TSH58p_13415 57208f43bf4bbc5eacf07bd1058a9909 220 Pfam PF13417 Glutathione S-transferase, N-terminal domain 12 82 1.7E-12 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 TSH58p_13415 57208f43bf4bbc5eacf07bd1058a9909 220 SUPERFAMILY SSF52833 4 88 1.72E-19 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_13415 57208f43bf4bbc5eacf07bd1058a9909 220 Gene3D G3DSA:3.40.30.10 6 201 1.4E-58 T 14-10-2018 TSH58p_13415 57208f43bf4bbc5eacf07bd1058a9909 220 Gene3D G3DSA:1.20.1050.10 85 195 1.4E-58 T 14-10-2018 TSH58p_28310 a8d1393f9b43a085c5f67195321f2191 211 SUPERFAMILY SSF52540 7 194 8.65E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_28310 a8d1393f9b43a085c5f67195321f2191 211 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 10 188 1.0E-69 T 14-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 TSH58p_28310 a8d1393f9b43a085c5f67195321f2191 211 SMART SM00072 8 191 6.5E-59 T 14-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit TSH58p_28310 a8d1393f9b43a085c5f67195321f2191 211 Pfam PF00625 Guanylate kinase 11 189 5.4E-49 T 14-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit TSH58p_28310 a8d1393f9b43a085c5f67195321f2191 211 ProSitePatterns PS00856 Guanylate kinase-like signature. 43 60 - T 14-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 TSH58p_28310 a8d1393f9b43a085c5f67195321f2191 211 Gene3D G3DSA:3.30.63.10 40 99 1.8E-63 T 14-10-2018 TSH58p_28310 a8d1393f9b43a085c5f67195321f2191 211 Hamap MF_00328 Guanylate kinase [gmk]. 7 191 35.083 T 14-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 TSH58p_28310 a8d1393f9b43a085c5f67195321f2191 211 Gene3D G3DSA:3.40.50.300 13 187 1.8E-63 T 14-10-2018 TSH58p_16085 5976e27577d09c6eb1200b8f6aea5152 196 Gene3D G3DSA:3.40.630.30 19 195 7.0E-54 T 14-10-2018 TSH58p_16085 5976e27577d09c6eb1200b8f6aea5152 196 Pfam PF13302 Acetyltransferase (GNAT) domain 24 166 3.5E-22 T 14-10-2018 IPR000182 GNAT domain TSH58p_16085 5976e27577d09c6eb1200b8f6aea5152 196 SUPERFAMILY SSF55729 14 191 1.98E-48 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_31465 1d735522d09a7acca377ec47f5d711de 391 SUPERFAMILY SSF55347 151 330 4.09E-41 T 14-10-2018 TSH58p_31465 1d735522d09a7acca377ec47f5d711de 391 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 15 144 7.5E-25 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 TSH58p_31465 1d735522d09a7acca377ec47f5d711de 391 Gene3D G3DSA:3.30.360.10 150 389 5.0E-143 T 14-10-2018 TSH58p_31465 1d735522d09a7acca377ec47f5d711de 391 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 157 278 3.3E-8 T 14-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 TSH58p_31465 1d735522d09a7acca377ec47f5d711de 391 Gene3D G3DSA:3.40.50.720 20 364 5.0E-143 T 14-10-2018 TSH58p_31465 1d735522d09a7acca377ec47f5d711de 391 SUPERFAMILY SSF51735 9 177 4.16E-40 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_24590 5772f9267082ec819a02138452aed677 400 Gene3D G3DSA:3.40.50.10540 4 394 8.7E-150 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily TSH58p_24590 5772f9267082ec819a02138452aed677 400 SUPERFAMILY SSF89796 2 400 3.92E-151 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily TSH58p_24590 5772f9267082ec819a02138452aed677 400 Pfam PF02515 CoA-transferase family III 5 376 1.3E-137 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 TSH58p_24590 5772f9267082ec819a02138452aed677 400 Gene3D G3DSA:3.30.1540.10 236 327 8.7E-150 T 14-10-2018 TSH58p_19900 f280396f76c53c62233a5cc5e5e140c0 379 Gene3D G3DSA:3.30.360.10 123 310 1.0E-65 T 14-10-2018 TSH58p_19900 f280396f76c53c62233a5cc5e5e140c0 379 Gene3D G3DSA:3.40.50.720 4 346 1.0E-65 T 14-10-2018 TSH58p_19900 f280396f76c53c62233a5cc5e5e140c0 379 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 122 342 1.1E-13 T 14-10-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 TSH58p_19900 f280396f76c53c62233a5cc5e5e140c0 379 SUPERFAMILY SSF55347 123 355 1.83E-60 T 14-10-2018 TSH58p_19900 f280396f76c53c62233a5cc5e5e140c0 379 SUPERFAMILY SSF51735 1 175 5.72E-21 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_19900 f280396f76c53c62233a5cc5e5e140c0 379 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 4 100 6.9E-18 T 14-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 TSH58p_01770 b75a78d68dc0d787ca23310623107d43 509 SUPERFAMILY SSF56801 9 499 9.29E-130 T 14-10-2018 TSH58p_01770 b75a78d68dc0d787ca23310623107d43 509 Pfam PF00501 AMP-binding enzyme 13 405 3.0E-87 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_01770 b75a78d68dc0d787ca23310623107d43 509 ProSitePatterns PS00455 Putative AMP-binding domain signature. 164 175 - T 14-10-2018 IPR020845 AMP-binding, conserved site TSH58p_01770 b75a78d68dc0d787ca23310623107d43 509 Gene3D G3DSA:3.40.50.12780 10 401 4.8E-101 T 14-10-2018 TSH58p_01770 b75a78d68dc0d787ca23310623107d43 509 Gene3D G3DSA:3.30.300.30 402 498 1.8E-19 T 14-10-2018 TSH58p_01770 b75a78d68dc0d787ca23310623107d43 509 Pfam PF13193 AMP-binding enzyme C-terminal domain 415 488 8.8E-11 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSH58p_06215 5fa34dadd30627e74662f52b81cfd185 140 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_06215 5fa34dadd30627e74662f52b81cfd185 140 SUPERFAMILY SSF64263 1 119 1.96E-48 T 14-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_06215 5fa34dadd30627e74662f52b81cfd185 140 Pfam PF01196 Ribosomal protein L17 20 116 2.1E-33 T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_06215 5fa34dadd30627e74662f52b81cfd185 140 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 117 4.9E-43 T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_06215 5fa34dadd30627e74662f52b81cfd185 140 Gene3D G3DSA:3.90.1030.10 1 117 5.7E-45 T 14-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_06215 5fa34dadd30627e74662f52b81cfd185 140 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 25.086 T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_12895 709cd8065717a3aaab5c34971e8ed8a5 318 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 314 2.1E-124 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSH58p_12895 709cd8065717a3aaab5c34971e8ed8a5 318 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 4 315 47.447 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSH58p_12895 709cd8065717a3aaab5c34971e8ed8a5 318 SUPERFAMILY SSF52096 4 314 1.9E-92 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_12895 709cd8065717a3aaab5c34971e8ed8a5 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 152 165 2.8E-39 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSH58p_12895 709cd8065717a3aaab5c34971e8ed8a5 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 112 130 2.8E-39 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSH58p_12895 709cd8065717a3aaab5c34971e8ed8a5 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 87 98 2.8E-39 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSH58p_12895 709cd8065717a3aaab5c34971e8ed8a5 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 168 181 2.8E-39 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSH58p_12895 709cd8065717a3aaab5c34971e8ed8a5 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 196 205 2.8E-39 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSH58p_12895 709cd8065717a3aaab5c34971e8ed8a5 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 133 149 2.8E-39 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSH58p_12895 709cd8065717a3aaab5c34971e8ed8a5 318 Gene3D G3DSA:3.90.226.10 1 315 3.9E-111 T 14-10-2018 TSH58p_12895 709cd8065717a3aaab5c34971e8ed8a5 318 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 5 147 6.7E-60 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSH58p_01060 b5e8f032a30bad0a11029c2f1139f0e5 404 Gene3D G3DSA:3.20.20.70 52 158 2.0E-6 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_01060 b5e8f032a30bad0a11029c2f1139f0e5 404 TIGRFAM TIGR03916 rSAM_link_UDG: putative DNA modification/repair radical SAM protein 6 399 6.5E-165 T 14-10-2018 IPR023874 DNA modification/repair radical SAM protein, putative TSH58p_01060 b5e8f032a30bad0a11029c2f1139f0e5 404 SUPERFAMILY SSF47781 301 373 1.0E-9 T 14-10-2018 IPR010994 RuvA domain 2-like TSH58p_01060 b5e8f032a30bad0a11029c2f1139f0e5 404 SMART SM00729 57 278 0.0054 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSH58p_01060 b5e8f032a30bad0a11029c2f1139f0e5 404 SUPERFAMILY SSF102114 45 256 5.59E-13 T 14-10-2018 TSH58p_11845 b051fa73601490ed4cfd8e0634bd21f3 204 Gene3D G3DSA:3.40.50.150 6 202 2.4E-18 T 14-10-2018 TSH58p_11845 b051fa73601490ed4cfd8e0634bd21f3 204 Pfam PF06080 Protein of unknown function (DUF938) 11 203 3.2E-70 T 14-10-2018 IPR010342 Protein of unknown function DUF938 TSH58p_11845 b051fa73601490ed4cfd8e0634bd21f3 204 SUPERFAMILY SSF53335 11 196 4.38E-25 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_07500 767fc3b35d29d88c636759a03aeb7a4c 41 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 16 41 0.009 T 14-10-2018 TSH58p_07500 767fc3b35d29d88c636759a03aeb7a4c 41 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 41 16.829 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_07500 767fc3b35d29d88c636759a03aeb7a4c 41 ProSitePatterns PS00828 Ribosomal protein L36 signature. 14 40 - T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_07500 767fc3b35d29d88c636759a03aeb7a4c 41 SUPERFAMILY SSF57840 1 41 1.31E-13 T 14-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_07500 767fc3b35d29d88c636759a03aeb7a4c 41 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 41 1.1E-7 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_07500 767fc3b35d29d88c636759a03aeb7a4c 41 Pfam PF00444 Ribosomal protein L36 1 41 3.9E-17 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_32345 bd70e5205905d2ed0e62e740d42014f6 377 Gene3D G3DSA:3.30.9.10 96 315 1.0E-75 T 14-10-2018 TSH58p_32345 bd70e5205905d2ed0e62e740d42014f6 377 SUPERFAMILY SSF51905 8 372 3.89E-46 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_32345 bd70e5205905d2ed0e62e740d42014f6 377 Gene3D G3DSA:3.50.50.60 10 351 1.0E-75 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_32345 bd70e5205905d2ed0e62e740d42014f6 377 Pfam PF01266 FAD dependent oxidoreductase 10 350 9.2E-50 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TSH58p_32345 bd70e5205905d2ed0e62e740d42014f6 377 SUPERFAMILY SSF54373 233 316 9.81E-14 T 14-10-2018 TSH58p_21060 394b157ffcdbcce4fa7e9b9e4641d3b6 766 Gene3D G3DSA:2.40.170.20 260 766 1.5E-60 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily TSH58p_21060 394b157ffcdbcce4fa7e9b9e4641d3b6 766 SMART SM00965 80 131 1.1E-12 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 TSH58p_21060 394b157ffcdbcce4fa7e9b9e4641d3b6 766 Pfam PF00593 TonB dependent receptor 347 763 1.2E-24 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel TSH58p_21060 394b157ffcdbcce4fa7e9b9e4641d3b6 766 Pfam PF07715 TonB-dependent Receptor Plug Domain 155 252 2.7E-12 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain TSH58p_21060 394b157ffcdbcce4fa7e9b9e4641d3b6 766 Gene3D G3DSA:3.55.50.30 50 150 4.2E-29 T 14-10-2018 TSH58p_21060 394b157ffcdbcce4fa7e9b9e4641d3b6 766 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 749 766 - T 14-10-2018 IPR010917 TonB-dependent receptor, conserved site TSH58p_21060 394b157ffcdbcce4fa7e9b9e4641d3b6 766 SUPERFAMILY SSF56935 153 766 6.59E-61 T 14-10-2018 TSH58p_21060 394b157ffcdbcce4fa7e9b9e4641d3b6 766 Gene3D G3DSA:2.170.130.10 151 258 8.6E-35 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily TSH58p_21060 394b157ffcdbcce4fa7e9b9e4641d3b6 766 Pfam PF07660 Secretin and TonB N terminus short domain 81 123 3.5E-7 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 TSH58p_31920 de834d8d8c25089d2f8bc055f1ded728 328 Pfam PF13379 NMT1-like family 34 267 5.2E-16 T 14-10-2018 TSH58p_31920 de834d8d8c25089d2f8bc055f1ded728 328 Gene3D G3DSA:3.40.190.10 114 220 3.5E-33 T 14-10-2018 TSH58p_31920 de834d8d8c25089d2f8bc055f1ded728 328 Gene3D G3DSA:3.40.190.10 39 311 3.5E-33 T 14-10-2018 TSH58p_31920 de834d8d8c25089d2f8bc055f1ded728 328 Gene3D G3DSA:1.10.8.450 252 282 3.5E-33 T 14-10-2018 TSH58p_31920 de834d8d8c25089d2f8bc055f1ded728 328 SUPERFAMILY SSF53850 36 263 1.41E-36 T 14-10-2018 TSH58p_10820 a1493b732de54a421bfba1e45e5f740d 164 SUPERFAMILY SSF46785 21 162 3.37E-38 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_10820 a1493b732de54a421bfba1e45e5f740d 164 Pfam PF01047 MarR family 58 114 4.7E-17 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_10820 a1493b732de54a421bfba1e45e5f740d 164 SMART SM00347 50 150 1.3E-32 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_10820 a1493b732de54a421bfba1e45e5f740d 164 Gene3D G3DSA:1.10.10.10 10 163 7.4E-41 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_10820 a1493b732de54a421bfba1e45e5f740d 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 110 126 2.7E-15 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_10820 a1493b732de54a421bfba1e45e5f740d 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 140 160 2.7E-15 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_10820 a1493b732de54a421bfba1e45e5f740d 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 106 2.7E-15 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_10820 a1493b732de54a421bfba1e45e5f740d 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 90 2.7E-15 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_09475 ed49336d11e1b8cf1215cb028d9d38a1 286 Hamap MF_01639 Pyridoxal kinase PdxY [pdxY]. 1 285 51.733 T 14-10-2018 IPR023685 Pyridoxal kinase PdxY GO:0008478|GO:0009443 KEGG: 00750+2.7.1.35|MetaCyc: PWY-7204|MetaCyc: PWY-7282 TSH58p_09475 ed49336d11e1b8cf1215cb028d9d38a1 286 Gene3D G3DSA:3.40.1190.20 1 286 2.0E-95 T 14-10-2018 IPR029056 Ribokinase-like TSH58p_09475 ed49336d11e1b8cf1215cb028d9d38a1 286 TIGRFAM TIGR00687 pyridox_kin: pyridoxal kinase 1 285 1.5E-112 T 14-10-2018 IPR004625 Pyridoxine kinase GO:0008478|GO:0009443 KEGG: 00750+2.7.1.35|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-6798695|Reactome: R-HSA-964975 TSH58p_09475 ed49336d11e1b8cf1215cb028d9d38a1 286 SUPERFAMILY SSF53613 1 277 1.53E-73 T 14-10-2018 IPR029056 Ribokinase-like TSH58p_09475 ed49336d11e1b8cf1215cb028d9d38a1 286 Pfam PF08543 Phosphomethylpyrimidine kinase 92 260 1.3E-15 T 14-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 TSH58p_16765 2afc7809e1242adc6aca6a086a581bf5 327 Gene3D G3DSA:3.40.50.150 104 292 5.5E-39 T 14-10-2018 TSH58p_16765 2afc7809e1242adc6aca6a086a581bf5 327 Pfam PF08241 Methyltransferase domain 153 249 5.9E-25 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TSH58p_16765 2afc7809e1242adc6aca6a086a581bf5 327 SMART SM00418 6 82 2.4E-18 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSH58p_16765 2afc7809e1242adc6aca6a086a581bf5 327 Gene3D G3DSA:1.10.10.10 1 91 2.4E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_16765 2afc7809e1242adc6aca6a086a581bf5 327 Pfam PF01022 Bacterial regulatory protein, arsR family 15 58 3.6E-11 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSH58p_16765 2afc7809e1242adc6aca6a086a581bf5 327 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 27 38 5.7E-12 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSH58p_16765 2afc7809e1242adc6aca6a086a581bf5 327 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 8 23 5.7E-12 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSH58p_16765 2afc7809e1242adc6aca6a086a581bf5 327 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 5.7E-12 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSH58p_16765 2afc7809e1242adc6aca6a086a581bf5 327 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 5.7E-12 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSH58p_16765 2afc7809e1242adc6aca6a086a581bf5 327 SUPERFAMILY SSF53335 114 296 7.68E-38 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_16765 2afc7809e1242adc6aca6a086a581bf5 327 SUPERFAMILY SSF46785 1 105 7.53E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_01955 6c7a79da399e74717f604bf0f0b73998 392 Pfam PF13527 Acetyltransferase (GNAT) domain 42 147 8.9E-9 T 14-10-2018 TSH58p_01955 6c7a79da399e74717f604bf0f0b73998 392 Gene3D G3DSA:3.40.630.30 16 149 6.0E-8 T 14-10-2018 TSH58p_01955 6c7a79da399e74717f604bf0f0b73998 392 SUPERFAMILY SSF55729 23 288 3.9E-16 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_28040 748aec12c81c5f204b49d708b6e7bd18 234 Pfam PF00301 Rubredoxin 17 61 3.7E-15 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 TSH58p_28040 748aec12c81c5f204b49d708b6e7bd18 234 ProDom PD008308 HUPJ HYDROGENASE EXPRESSION/FORMATION HYDROGENASE-2 HYBE COMPONENT OPERON ELECTRON METAL-BINDING IRON 81 183 3.0E-14 T 14-10-2018 IPR023994 [NiFe]-hydrogenase assembly, chaperone, HybE TSH58p_28040 748aec12c81c5f204b49d708b6e7bd18 234 TIGRFAM TIGR03993 hydrog_HybE: [NiFe] hydrogenase assembly chaperone, HybE family 78 229 3.4E-37 T 14-10-2018 IPR023994 [NiFe]-hydrogenase assembly, chaperone, HybE TSH58p_28040 748aec12c81c5f204b49d708b6e7bd18 234 SUPERFAMILY SSF57802 17 65 8.58E-15 T 14-10-2018 TSH58p_28040 748aec12c81c5f204b49d708b6e7bd18 234 Pfam PF11939 [NiFe]-hydrogenase assembly, chaperone, HybE 75 230 2.1E-44 T 14-10-2018 IPR023994 [NiFe]-hydrogenase assembly, chaperone, HybE TSH58p_28040 748aec12c81c5f204b49d708b6e7bd18 234 Gene3D G3DSA:2.20.28.10 14 66 8.3E-18 T 14-10-2018 TSH58p_28040 748aec12c81c5f204b49d708b6e7bd18 234 ProSitePatterns PS00202 Rubredoxin signature. 45 55 - T 14-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 TSH58p_28040 748aec12c81c5f204b49d708b6e7bd18 234 Gene3D G3DSA:3.30.1460.40 71 198 1.8E-34 T 14-10-2018 IPR038530 [NiFe]-hydrogenase assembly, chaperone, HybE superfamily TSH58p_28040 748aec12c81c5f204b49d708b6e7bd18 234 PRINTS PR00163 Rubredoxin signature 15 31 1.1E-6 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 TSH58p_28040 748aec12c81c5f204b49d708b6e7bd18 234 PRINTS PR00163 Rubredoxin signature 45 61 1.1E-6 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 TSH58p_21100 d066c92fec21579ab3622e2cf33ef994 284 Gene3D G3DSA:1.10.3720.10 10 283 1.4E-38 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_21100 d066c92fec21579ab3622e2cf33ef994 284 SUPERFAMILY SSF161098 13 282 9.35E-40 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_21100 d066c92fec21579ab3622e2cf33ef994 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 55 273 7.9E-10 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_05415 331fe7241671ef7045e0a548fea9d177 269 Gene3D G3DSA:1.10.3720.10 56 256 3.6E-21 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_05415 331fe7241671ef7045e0a548fea9d177 269 SUPERFAMILY SSF161098 61 245 1.09E-27 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_05415 331fe7241671ef7045e0a548fea9d177 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 253 2.1E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_29665 d5bc1130f0515a9d1416fdc8abf47db0 193 Gene3D G3DSA:3.40.50.1010 1 159 9.0E-51 T 14-10-2018 TSH58p_29665 d5bc1130f0515a9d1416fdc8abf47db0 193 Pfam PF01936 NYN domain 2 155 5.3E-36 T 14-10-2018 IPR021139 NYN domain, limkain-b1-type TSH58p_01395 6ca295a97b082eb307f6114599f8afbb 403 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 291 304 1.7E-10 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_01395 6ca295a97b082eb307f6114599f8afbb 403 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 33 49 1.7E-10 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_01395 6ca295a97b082eb307f6114599f8afbb 403 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 55 71 1.7E-10 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_01395 6ca295a97b082eb307f6114599f8afbb 403 Gene3D G3DSA:3.40.50.2300 157 284 5.8E-108 T 14-10-2018 TSH58p_01395 6ca295a97b082eb307f6114599f8afbb 403 Gene3D G3DSA:3.40.50.2300 39 373 5.8E-108 T 14-10-2018 TSH58p_01395 6ca295a97b082eb307f6114599f8afbb 403 Pfam PF13458 Periplasmic binding protein 32 387 2.3E-70 T 14-10-2018 IPR028081 Leucine-binding protein domain TSH58p_01395 6ca295a97b082eb307f6114599f8afbb 403 SUPERFAMILY SSF53822 32 388 6.73E-78 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_00900 ca4006d8f6a1acf744e71112d58aaa0c 224 Gene3D G3DSA:1.10.287.470 40 99 1.1E-35 T 14-10-2018 TSH58p_00900 ca4006d8f6a1acf744e71112d58aaa0c 224 SUPERFAMILY SSF111369 3 190 5.62E-21 T 14-10-2018 TSH58p_00900 ca4006d8f6a1acf744e71112d58aaa0c 224 Gene3D G3DSA:2.40.30.170 2 216 1.1E-35 T 14-10-2018 TSH58p_00900 ca4006d8f6a1acf744e71112d58aaa0c 224 Gene3D G3DSA:2.40.50.100 6 138 1.1E-35 T 14-10-2018 TSH58p_00900 ca4006d8f6a1acf744e71112d58aaa0c 224 Pfam PF13437 HlyD family secretion protein 104 200 9.1E-18 T 14-10-2018 TSH58p_00900 ca4006d8f6a1acf744e71112d58aaa0c 224 Pfam PF13533 Biotin-lipoyl like 10 54 8.7E-8 T 14-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain TSH58p_00900 ca4006d8f6a1acf744e71112d58aaa0c 224 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 2 216 9.0E-34 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 TSH58p_10360 79fbcdae625e9fb35f28e290a94e9db8 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 251 2.4E-13 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_10360 79fbcdae625e9fb35f28e290a94e9db8 269 Gene3D G3DSA:1.10.3720.10 58 258 4.0E-15 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_10360 79fbcdae625e9fb35f28e290a94e9db8 269 SUPERFAMILY SSF161098 64 248 3.14E-16 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_12965 f2913558d67be2442f560aac3d5e2809 307 Pfam PF00535 Glycosyl transferase family 2 5 126 7.5E-27 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_12965 f2913558d67be2442f560aac3d5e2809 307 Gene3D G3DSA:3.90.550.10 1 200 1.2E-42 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_12965 f2913558d67be2442f560aac3d5e2809 307 SUPERFAMILY SSF53448 1 228 1.29E-47 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_02470 009c522f1c76d2a18a81e1c3fadc21da 393 Hamap MF_01201 Alanine racemase. 11 383 22.334 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_02470 009c522f1c76d2a18a81e1c3fadc21da 393 TIGRFAM TIGR00492 alr: alanine racemase 14 365 3.8E-58 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_02470 009c522f1c76d2a18a81e1c3fadc21da 393 Pfam PF00842 Alanine racemase, C-terminal domain 256 382 3.5E-23 T 14-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_02470 009c522f1c76d2a18a81e1c3fadc21da 393 Gene3D G3DSA:2.40.37.10 243 382 6.0E-30 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TSH58p_02470 009c522f1c76d2a18a81e1c3fadc21da 393 SUPERFAMILY SSF51419 18 257 1.89E-44 T 14-10-2018 IPR029066 PLP-binding barrel TSH58p_02470 009c522f1c76d2a18a81e1c3fadc21da 393 SUPERFAMILY SSF50621 250 383 1.36E-28 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TSH58p_02470 009c522f1c76d2a18a81e1c3fadc21da 393 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 42 52 - T 14-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_02470 009c522f1c76d2a18a81e1c3fadc21da 393 Pfam PF01168 Alanine racemase, N-terminal domain 18 243 6.2E-49 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_02470 009c522f1c76d2a18a81e1c3fadc21da 393 SMART SM01005 256 383 2.6E-21 T 14-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_02470 009c522f1c76d2a18a81e1c3fadc21da 393 PRINTS PR00992 Alanine racemase signature 289 304 1.6E-25 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_02470 009c522f1c76d2a18a81e1c3fadc21da 393 PRINTS PR00992 Alanine racemase signature 73 91 1.6E-25 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_02470 009c522f1c76d2a18a81e1c3fadc21da 393 PRINTS PR00992 Alanine racemase signature 168 179 1.6E-25 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_02470 009c522f1c76d2a18a81e1c3fadc21da 393 PRINTS PR00992 Alanine racemase signature 310 327 1.6E-25 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_02470 009c522f1c76d2a18a81e1c3fadc21da 393 PRINTS PR00992 Alanine racemase signature 37 53 1.6E-25 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_02470 009c522f1c76d2a18a81e1c3fadc21da 393 PRINTS PR00992 Alanine racemase signature 134 146 1.6E-25 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_02470 009c522f1c76d2a18a81e1c3fadc21da 393 PRINTS PR00992 Alanine racemase signature 272 287 1.6E-25 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_02470 009c522f1c76d2a18a81e1c3fadc21da 393 Gene3D G3DSA:3.20.20.10 20 242 6.7E-53 T 14-10-2018 IPR029066 PLP-binding barrel TSH58p_29220 cd19b6314dd2eea38b113d0f84ad0b48 243 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_29220 cd19b6314dd2eea38b113d0f84ad0b48 243 SUPERFAMILY SSF51735 5 242 4.54E-69 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_29220 cd19b6314dd2eea38b113d0f84ad0b48 243 Gene3D G3DSA:3.40.50.720 2 242 1.4E-68 T 14-10-2018 TSH58p_29220 cd19b6314dd2eea38b113d0f84ad0b48 243 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 187 0.0026 T 14-10-2018 TSH58p_29220 cd19b6314dd2eea38b113d0f84ad0b48 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 3.7E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_29220 cd19b6314dd2eea38b113d0f84ad0b48 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 3.7E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_29220 cd19b6314dd2eea38b113d0f84ad0b48 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 3.7E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_29220 cd19b6314dd2eea38b113d0f84ad0b48 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 4.2E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_29220 cd19b6314dd2eea38b113d0f84ad0b48 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 4.2E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_29220 cd19b6314dd2eea38b113d0f84ad0b48 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 4.2E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_29220 cd19b6314dd2eea38b113d0f84ad0b48 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 4.2E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_29220 cd19b6314dd2eea38b113d0f84ad0b48 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 4.2E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_29220 cd19b6314dd2eea38b113d0f84ad0b48 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 4.2E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_29220 cd19b6314dd2eea38b113d0f84ad0b48 243 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 242 1.3E-49 T 14-10-2018 TSH58p_24655 3efb8306666fdd5bd7de84f3334d67c9 154 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 15 151 2.1E-34 T 14-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like TSH58p_24655 3efb8306666fdd5bd7de84f3334d67c9 154 Gene3D G3DSA:3.30.530.20 1 153 1.7E-45 T 14-10-2018 IPR023393 START-like domain superfamily TSH58p_24655 3efb8306666fdd5bd7de84f3334d67c9 154 SUPERFAMILY SSF55961 3 153 2.32E-47 T 14-10-2018 TSH58p_27470 e97d5557add0d3faabab0d3c9cfc04f7 159 Pfam PF01613 Flavin reductase like domain 13 158 9.6E-38 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 TSH58p_27470 e97d5557add0d3faabab0d3c9cfc04f7 159 SMART SM00903 12 157 6.7E-58 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 TSH58p_27470 e97d5557add0d3faabab0d3c9cfc04f7 159 Gene3D G3DSA:2.30.110.10 1 159 1.4E-52 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TSH58p_27470 e97d5557add0d3faabab0d3c9cfc04f7 159 SUPERFAMILY SSF50475 8 158 8.51E-49 T 14-10-2018 TSH58p_26865 f3052b89db3e6e71249f2be94e1f15cc 523 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 76 433 4.4E-94 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain TSH58p_26865 f3052b89db3e6e71249f2be94e1f15cc 523 Gene3D G3DSA:3.90.76.10 44 199 3.9E-142 T 14-10-2018 TSH58p_26865 f3052b89db3e6e71249f2be94e1f15cc 523 PIRSF PIRSF002741 9 519 6.9E-117 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TSH58p_26865 f3052b89db3e6e71249f2be94e1f15cc 523 Gene3D G3DSA:3.40.190.10 200 511 3.9E-142 T 14-10-2018 TSH58p_26865 f3052b89db3e6e71249f2be94e1f15cc 523 Gene3D G3DSA:3.10.105.10 279 499 3.9E-142 T 14-10-2018 TSH58p_26865 f3052b89db3e6e71249f2be94e1f15cc 523 SUPERFAMILY SSF53850 28 522 6.33E-140 T 14-10-2018 TSH58p_07430 414e78dedbece3d19f4c099839fbb7b5 323 Gene3D G3DSA:3.40.50.11030 214 322 4.5E-18 T 14-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily TSH58p_07430 414e78dedbece3d19f4c099839fbb7b5 323 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 15 209 1.4E-57 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 TSH58p_07430 414e78dedbece3d19f4c099839fbb7b5 323 Gene3D G3DSA:3.90.870.10 7 213 6.4E-76 T 14-10-2018 TSH58p_07430 414e78dedbece3d19f4c099839fbb7b5 323 Pfam PF03481 Putative GTP-binding controlling metal-binding 202 320 5.8E-22 T 14-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain TSH58p_07430 414e78dedbece3d19f4c099839fbb7b5 323 SUPERFAMILY SSF55821 14 211 1.19E-62 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily TSH58p_07430 414e78dedbece3d19f4c099839fbb7b5 323 PIRSF PIRSF004930 8 323 1.8E-108 T 14-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 TSH58p_07430 414e78dedbece3d19f4c099839fbb7b5 323 Pfam PF01300 Telomere recombination 21 198 7.7E-57 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 TSH58p_04690 9289d8fd1578e2ac3eba0e4798e83c66 422 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 264 297 - T 14-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 TSH58p_04690 9289d8fd1578e2ac3eba0e4798e83c66 422 Pfam PF03453 MoeA N-terminal region (domain I and II) 17 178 2.4E-44 T 14-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_04690 9289d8fd1578e2ac3eba0e4798e83c66 422 SUPERFAMILY SSF63882 15 185 1.05E-53 T 14-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_04690 9289d8fd1578e2ac3eba0e4798e83c66 422 SUPERFAMILY SSF53218 188 337 4.97E-40 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSH58p_04690 9289d8fd1578e2ac3eba0e4798e83c66 422 Gene3D G3DSA:2.170.190.11 59 152 3.7E-130 T 14-10-2018 TSH58p_04690 9289d8fd1578e2ac3eba0e4798e83c66 422 SUPERFAMILY SSF63867 345 420 3.27E-19 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_04690 9289d8fd1578e2ac3eba0e4798e83c66 422 Gene3D G3DSA:2.40.340.10 343 413 3.7E-130 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_04690 9289d8fd1578e2ac3eba0e4798e83c66 422 Gene3D G3DSA:3.40.980.10 186 342 3.7E-130 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSH58p_04690 9289d8fd1578e2ac3eba0e4798e83c66 422 SMART SM00852 191 333 1.4E-41 T 14-10-2018 IPR001453 MoaB/Mog domain TSH58p_04690 9289d8fd1578e2ac3eba0e4798e83c66 422 Pfam PF00994 Probable molybdopterin binding domain 191 331 5.1E-27 T 14-10-2018 IPR001453 MoaB/Mog domain TSH58p_04690 9289d8fd1578e2ac3eba0e4798e83c66 422 Pfam PF03454 MoeA C-terminal region (domain IV) 347 418 1.3E-14 T 14-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSH58p_04690 9289d8fd1578e2ac3eba0e4798e83c66 422 Gene3D G3DSA:3.90.105.10 36 185 3.7E-130 T 14-10-2018 TSH58p_05795 fb3085f40edbff723b94873f74e36da5 225 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_05795 fb3085f40edbff723b94873f74e36da5 225 Pfam PF00005 ABC transporter 22 169 3.6E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_05795 fb3085f40edbff723b94873f74e36da5 225 SUPERFAMILY SSF52540 1 223 2.66E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_05795 fb3085f40edbff723b94873f74e36da5 225 SMART SM00382 30 218 3.4E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_05795 fb3085f40edbff723b94873f74e36da5 225 Gene3D G3DSA:3.40.50.300 1 225 7.4E-64 T 14-10-2018 TSH58p_12075 bfe31cefb6f98276d91ae38a38e4d795 663 Pfam PF01578 Cytochrome C assembly protein 89 296 1.8E-52 T 14-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 TSH58p_12075 bfe31cefb6f98276d91ae38a38e4d795 663 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 315 642 7.8E-124 T 14-10-2018 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal TSH58p_12075 bfe31cefb6f98276d91ae38a38e4d795 663 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 53 645 1.2E-201 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSH58p_12075 bfe31cefb6f98276d91ae38a38e4d795 663 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 310 329 5.8E-95 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSH58p_12075 bfe31cefb6f98276d91ae38a38e4d795 663 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 159 181 5.8E-95 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSH58p_12075 bfe31cefb6f98276d91ae38a38e4d795 663 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 244 264 5.8E-95 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSH58p_12075 bfe31cefb6f98276d91ae38a38e4d795 663 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 80 106 5.8E-95 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSH58p_12075 bfe31cefb6f98276d91ae38a38e4d795 663 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 210 236 5.8E-95 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSH58p_12075 bfe31cefb6f98276d91ae38a38e4d795 663 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 132 149 5.8E-95 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSH58p_12075 bfe31cefb6f98276d91ae38a38e4d795 663 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 274 294 5.8E-95 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSH58p_12075 bfe31cefb6f98276d91ae38a38e4d795 663 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 294 310 5.8E-95 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSH58p_12075 bfe31cefb6f98276d91ae38a38e4d795 663 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 394 413 2.2E-60 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSH58p_12075 bfe31cefb6f98276d91ae38a38e4d795 663 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 635 648 2.2E-60 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSH58p_12075 bfe31cefb6f98276d91ae38a38e4d795 663 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 113 136 2.2E-60 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSH58p_12075 bfe31cefb6f98276d91ae38a38e4d795 663 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 351 368 2.2E-60 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSH58p_12075 bfe31cefb6f98276d91ae38a38e4d795 663 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 4 28 2.2E-60 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSH58p_12075 bfe31cefb6f98276d91ae38a38e4d795 663 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 189 204 2.2E-60 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSH58p_12075 bfe31cefb6f98276d91ae38a38e4d795 663 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 313 328 2.2E-60 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSH58p_26540 c19b0712f785cc6cd03eee42ac48187e 162 Pfam PF01899 Na+/H+ ion antiporter subunit 12 160 2.0E-36 T 14-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TSH58p_26540 c19b0712f785cc6cd03eee42ac48187e 162 PIRSF PIRSF019239 1 162 2.4E-35 T 14-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TSH58p_15000 eb4a697952fa0f65b44b230688f1ea5b 238 Pfam PF00005 ABC transporter 22 166 6.7E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_15000 eb4a697952fa0f65b44b230688f1ea5b 238 Gene3D G3DSA:3.40.50.300 2 238 2.5E-62 T 14-10-2018 TSH58p_15000 eb4a697952fa0f65b44b230688f1ea5b 238 SMART SM00382 31 217 1.9E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_15000 eb4a697952fa0f65b44b230688f1ea5b 238 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_15000 eb4a697952fa0f65b44b230688f1ea5b 238 SUPERFAMILY SSF52540 5 234 1.57E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_14840 d57858125563f5ee857fa2cd33fdd193 102 SUPERFAMILY SSF47090 27 91 7.06E-16 T 14-10-2018 IPR036365 PGBD-like superfamily TSH58p_14840 d57858125563f5ee857fa2cd33fdd193 102 Pfam PF01471 Putative peptidoglycan binding domain 37 87 4.8E-11 T 14-10-2018 IPR002477 Peptidoglycan binding-like TSH58p_14840 d57858125563f5ee857fa2cd33fdd193 102 Gene3D G3DSA:1.10.101.10 24 92 7.4E-12 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 TSH58p_23730 33f976f0183161394843f6f530459131 554 Gene3D G3DSA:2.170.16.10 383 513 3.1E-15 T 14-10-2018 TSH58p_23730 33f976f0183161394843f6f530459131 554 SUPERFAMILY SSF51294 383 512 8.11E-13 T 14-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSH58p_23730 33f976f0183161394843f6f530459131 554 SMART SM00306 381 471 0.0055 T 14-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSH58p_22330 d777d19dd1bf887bae3e20e745e841cd 87 Gene3D G3DSA:3.40.50.300 20 85 1.4E-9 T 14-10-2018 TSH58p_22330 d777d19dd1bf887bae3e20e745e841cd 87 SUPERFAMILY SSF52540 28 77 1.15E-8 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_17345 910714b5916346a96c9de79dd91847e8 92 Pfam PF12728 Helix-turn-helix domain 1 48 2.3E-6 T 14-10-2018 TSH58p_17345 910714b5916346a96c9de79dd91847e8 92 Gene3D G3DSA:1.10.1660.10 1 47 5.6E-8 T 14-10-2018 TSH58p_17345 910714b5916346a96c9de79dd91847e8 92 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 1 44 3.6E-8 T 14-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 TSH58p_19915 ce830f41c4dc00700ce1a697a1f8a9a9 734 Gene3D G3DSA:3.90.1170.50 193 292 4.0E-12 T 14-10-2018 TSH58p_19915 ce830f41c4dc00700ce1a697a1f8a9a9 734 PIRSF PIRSF036389 6 734 8.4E-252 T 14-10-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related TSH58p_19915 ce830f41c4dc00700ce1a697a1f8a9a9 734 Gene3D G3DSA:3.30.365.10 352 448 1.8E-60 T 14-10-2018 TSH58p_19915 ce830f41c4dc00700ce1a697a1f8a9a9 734 SUPERFAMILY SSF56003 17 255 5.23E-37 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 TSH58p_19915 ce830f41c4dc00700ce1a697a1f8a9a9 734 Gene3D G3DSA:3.30.365.10 328 562 1.8E-60 T 14-10-2018 TSH58p_19915 ce830f41c4dc00700ce1a697a1f8a9a9 734 SMART SM01008 222 300 3.0E-23 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead TSH58p_19915 ce830f41c4dc00700ce1a697a1f8a9a9 734 Gene3D G3DSA:3.30.365.10 53 192 4.5E-18 T 14-10-2018 TSH58p_19915 ce830f41c4dc00700ce1a697a1f8a9a9 734 SUPERFAMILY SSF56003 323 731 3.93E-124 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 TSH58p_19915 ce830f41c4dc00700ce1a697a1f8a9a9 734 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 57 204 7.8E-10 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 TSH58p_19915 ce830f41c4dc00700ce1a697a1f8a9a9 734 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 319 562 1.3E-34 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 TSH58p_19915 ce830f41c4dc00700ce1a697a1f8a9a9 734 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 601 683 2.9E-17 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 TSH58p_19915 ce830f41c4dc00700ce1a697a1f8a9a9 734 Gene3D G3DSA:3.30.365.10 588 734 2.8E-41 T 14-10-2018 TSH58p_19915 ce830f41c4dc00700ce1a697a1f8a9a9 734 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 223 271 2.6E-4 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead TSH58p_04490 bb206370231cdf84b023732c547cd9db 228 Pfam PF10691 Protein of unknown function (DUF2497) 148 223 4.2E-24 T 14-10-2018 IPR019632 Protein of unknown function DUF2497 TSH58p_04490 bb206370231cdf84b023732c547cd9db 228 PRINTS PR00806 Vinculin signature 33 43 1.6E-5 T 14-10-2018 TSH58p_04490 bb206370231cdf84b023732c547cd9db 228 PRINTS PR00806 Vinculin signature 49 62 1.6E-5 T 14-10-2018 TSH58p_21015 ee8ab2916d8a3190d225954c07120c50 235 SMART SM00100 26 143 1.0E-11 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_21015 ee8ab2916d8a3190d225954c07120c50 235 Gene3D G3DSA:1.10.10.10 159 232 1.3E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_21015 ee8ab2916d8a3190d225954c07120c50 235 Pfam PF00027 Cyclic nucleotide-binding domain 45 129 1.6E-15 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_21015 ee8ab2916d8a3190d225954c07120c50 235 SUPERFAMILY SSF51206 19 157 1.44E-25 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like TSH58p_21015 ee8ab2916d8a3190d225954c07120c50 235 SUPERFAMILY SSF46785 160 232 1.18E-8 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_21015 ee8ab2916d8a3190d225954c07120c50 235 Pfam PF13545 Crp-like helix-turn-helix domain 164 230 3.3E-10 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_21015 ee8ab2916d8a3190d225954c07120c50 235 Gene3D G3DSA:2.60.120.10 42 158 5.2E-27 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_21290 c5c812ad767eaac9bebce53f732107c3 567 Gene3D G3DSA:3.40.50.12780 25 461 4.9E-122 T 14-10-2018 TSH58p_21290 c5c812ad767eaac9bebce53f732107c3 567 Pfam PF00501 AMP-binding enzyme 37 465 6.7E-110 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_21290 c5c812ad767eaac9bebce53f732107c3 567 SUPERFAMILY SSF56801 18 560 1.31E-152 T 14-10-2018 TSH58p_21290 c5c812ad767eaac9bebce53f732107c3 567 ProSitePatterns PS00455 Putative AMP-binding domain signature. 217 228 - T 14-10-2018 IPR020845 AMP-binding, conserved site TSH58p_21290 c5c812ad767eaac9bebce53f732107c3 567 Pfam PF13193 AMP-binding enzyme C-terminal domain 476 550 7.2E-18 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSH58p_21290 c5c812ad767eaac9bebce53f732107c3 567 Gene3D G3DSA:3.30.300.30 462 564 2.6E-26 T 14-10-2018 TSH58p_07970 2fab8e1ac7ded53a776dc4c7a7a73d56 198 PRINTS PR00354 7Fe ferredoxin signature 55 65 2.6E-5 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TSH58p_07970 2fab8e1ac7ded53a776dc4c7a7a73d56 198 PRINTS PR00354 7Fe ferredoxin signature 82 99 2.6E-5 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TSH58p_07970 2fab8e1ac7ded53a776dc4c7a7a73d56 198 PRINTS PR00354 7Fe ferredoxin signature 65 75 2.6E-5 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TSH58p_07970 2fab8e1ac7ded53a776dc4c7a7a73d56 198 Gene3D G3DSA:3.30.70.20 5 172 5.5E-35 T 14-10-2018 TSH58p_07970 2fab8e1ac7ded53a776dc4c7a7a73d56 198 SUPERFAMILY SSF54862 1 180 1.88E-49 T 14-10-2018 TSH58p_07970 2fab8e1ac7ded53a776dc4c7a7a73d56 198 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 87 98 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_07970 2fab8e1ac7ded53a776dc4c7a7a73d56 198 Pfam PF13247 4Fe-4S dicluster domain 52 164 6.0E-10 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_07970 2fab8e1ac7ded53a776dc4c7a7a73d56 198 Gene3D G3DSA:3.30.70.20 61 118 5.5E-35 T 14-10-2018 TSH58p_31530 23cdab769a64a85f84c4bca98b35969c 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 8.2E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_31530 23cdab769a64a85f84c4bca98b35969c 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 8.2E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_31530 23cdab769a64a85f84c4bca98b35969c 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 8.2E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_31530 23cdab769a64a85f84c4bca98b35969c 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 8.2E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_31530 23cdab769a64a85f84c4bca98b35969c 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 8.2E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_31530 23cdab769a64a85f84c4bca98b35969c 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 8.2E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_31530 23cdab769a64a85f84c4bca98b35969c 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.1E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_31530 23cdab769a64a85f84c4bca98b35969c 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 2.1E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_31530 23cdab769a64a85f84c4bca98b35969c 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.1E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_31530 23cdab769a64a85f84c4bca98b35969c 263 SUPERFAMILY SSF51735 6 261 1.91E-72 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_31530 23cdab769a64a85f84c4bca98b35969c 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 260 6.2E-54 T 14-10-2018 TSH58p_31530 23cdab769a64a85f84c4bca98b35969c 263 Gene3D G3DSA:3.40.50.720 2 262 5.1E-74 T 14-10-2018 TSH58p_26665 2a1c438d59238bf1e6ab0c00dde12a5b 421 Pfam PF01547 Bacterial extracellular solute-binding protein 54 331 2.7E-30 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSH58p_26665 2a1c438d59238bf1e6ab0c00dde12a5b 421 SUPERFAMILY SSF53850 52 412 1.04E-62 T 14-10-2018 TSH58p_26665 2a1c438d59238bf1e6ab0c00dde12a5b 421 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 147 164 - T 14-10-2018 IPR006061 Solute-binding family 1, conserved site GO:0055085 TSH58p_26665 2a1c438d59238bf1e6ab0c00dde12a5b 421 Gene3D G3DSA:3.40.190.10 49 420 2.0E-58 T 14-10-2018 TSH58p_31060 1154ee2a1f53fe0b4a844d564d7d2a8e 269 Gene3D G3DSA:2.60.120.10 17 97 7.1E-10 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_31060 1154ee2a1f53fe0b4a844d564d7d2a8e 269 Pfam PF12833 Helix-turn-helix domain 181 258 2.3E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TSH58p_31060 1154ee2a1f53fe0b4a844d564d7d2a8e 269 Gene3D G3DSA:1.10.10.60 159 265 4.0E-18 T 14-10-2018 TSH58p_31060 1154ee2a1f53fe0b4a844d564d7d2a8e 269 Pfam PF02311 AraC-like ligand binding domain 32 103 1.2E-8 T 14-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 TSH58p_31060 1154ee2a1f53fe0b4a844d564d7d2a8e 269 SUPERFAMILY SSF46689 214 259 1.39E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_31060 1154ee2a1f53fe0b4a844d564d7d2a8e 269 SUPERFAMILY SSF51182 27 184 9.71E-19 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_31060 1154ee2a1f53fe0b4a844d564d7d2a8e 269 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 241 257 6.4E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TSH58p_31060 1154ee2a1f53fe0b4a844d564d7d2a8e 269 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 226 241 6.4E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TSH58p_31060 1154ee2a1f53fe0b4a844d564d7d2a8e 269 SMART SM00342 175 257 7.8E-17 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TSH58p_03705 7846174622f7d0df8ac9740830762bbc 249 SUPERFAMILY SSF46894 164 220 5.44E-9 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_03705 7846174622f7d0df8ac9740830762bbc 249 Gene3D G3DSA:1.10.10.10 98 243 1.9E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_03705 7846174622f7d0df8ac9740830762bbc 249 SMART SM00421 171 233 7.6E-5 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_03280 2aaf04fdaada54e34db8e659dbb1474d 306 SUPERFAMILY SSF103481 51 152 1.7E-10 T 14-10-2018 TSH58p_03280 2aaf04fdaada54e34db8e659dbb1474d 306 Pfam PF00892 EamA-like transporter family 162 298 3.6E-15 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_03280 2aaf04fdaada54e34db8e659dbb1474d 306 Pfam PF00892 EamA-like transporter family 20 148 3.9E-14 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_03280 2aaf04fdaada54e34db8e659dbb1474d 306 SUPERFAMILY SSF103481 198 300 1.57E-10 T 14-10-2018 TSH58p_15320 e344d240ea6dfe564577df42c6da651c 74 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 69 1.3E-34 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15320 e344d240ea6dfe564577df42c6da651c 74 PRINTS PR01249 Ribosomal protein L31 signature 2 19 2.2E-14 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15320 e344d240ea6dfe564577df42c6da651c 74 PRINTS PR01249 Ribosomal protein L31 signature 34 49 2.2E-14 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15320 e344d240ea6dfe564577df42c6da651c 74 PRINTS PR01249 Ribosomal protein L31 signature 49 67 2.2E-14 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15320 e344d240ea6dfe564577df42c6da651c 74 Gene3D G3DSA:2.30.170.50 1 73 1.1E-25 T 14-10-2018 TSH58p_15320 e344d240ea6dfe564577df42c6da651c 74 ProSitePatterns PS01143 Ribosomal protein L31 signature. 38 59 - T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15320 e344d240ea6dfe564577df42c6da651c 74 Pfam PF01197 Ribosomal protein L31 1 68 1.4E-27 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15320 e344d240ea6dfe564577df42c6da651c 74 SUPERFAMILY SSF143800 1 70 1.1E-23 T 14-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_15320 e344d240ea6dfe564577df42c6da651c 74 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 71 26.66 T 14-10-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_04545 19c8349a2575efb404829eefd36f4122 392 Pfam PF07007 Lysozyme inhibitor LprI 29 96 4.8E-5 T 14-10-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal TSH58p_06035 41410242d09cb24f11f42b6cec737ded 266 SUPERFAMILY SSF53613 3 261 2.65E-80 T 14-10-2018 IPR029056 Ribokinase-like TSH58p_06035 41410242d09cb24f11f42b6cec737ded 266 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 5 258 2.6E-99 T 14-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSH58p_06035 41410242d09cb24f11f42b6cec737ded 266 Pfam PF08543 Phosphomethylpyrimidine kinase 12 257 1.2E-91 T 14-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 TSH58p_06035 41410242d09cb24f11f42b6cec737ded 266 Gene3D G3DSA:3.40.1190.20 2 264 1.1E-101 T 14-10-2018 IPR029056 Ribokinase-like TSH58p_25520 d2c4ea0a12dc68a2cff6a81fb98bd10e 339 Pfam PF13614 AAA domain 77 254 1.5E-53 T 14-10-2018 IPR025669 AAA domain TSH58p_25520 d2c4ea0a12dc68a2cff6a81fb98bd10e 339 SUPERFAMILY SSF52540 77 331 1.25E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_25520 d2c4ea0a12dc68a2cff6a81fb98bd10e 339 Gene3D G3DSA:3.40.50.300 72 338 1.8E-72 T 14-10-2018 TSH58p_22165 cb25e4f8751d1997d71fb4cdff0d5c09 208 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 15 31 0.058 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_22165 cb25e4f8751d1997d71fb4cdff0d5c09 208 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 55 71 0.005 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_22165 cb25e4f8751d1997d71fb4cdff0d5c09 208 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 72 89 8.4E-5 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_22165 cb25e4f8751d1997d71fb4cdff0d5c09 208 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 91 107 9.6E-4 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_22165 cb25e4f8751d1997d71fb4cdff0d5c09 208 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 33 49 0.0068 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_22165 cb25e4f8751d1997d71fb4cdff0d5c09 208 Gene3D G3DSA:2.150.10.10 51 111 1.0E-14 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_22165 cb25e4f8751d1997d71fb4cdff0d5c09 208 Gene3D G3DSA:2.150.10.10 1 50 2.2E-9 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_22165 cb25e4f8751d1997d71fb4cdff0d5c09 208 Gene3D G3DSA:2.150.10.10 112 204 1.0E-5 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_22165 cb25e4f8751d1997d71fb4cdff0d5c09 208 SUPERFAMILY SSF51120 12 194 9.63E-25 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_22165 cb25e4f8751d1997d71fb4cdff0d5c09 208 PRINTS PR00313 NodO calcium binding signature 73 81 7.8E-11 T 14-10-2018 TSH58p_22165 cb25e4f8751d1997d71fb4cdff0d5c09 208 PRINTS PR00313 NodO calcium binding signature 30 41 7.8E-11 T 14-10-2018 TSH58p_22165 cb25e4f8751d1997d71fb4cdff0d5c09 208 PRINTS PR00313 NodO calcium binding signature 91 100 7.8E-11 T 14-10-2018 TSH58p_22165 cb25e4f8751d1997d71fb4cdff0d5c09 208 PRINTS PR00313 NodO calcium binding signature 82 90 7.8E-11 T 14-10-2018 TSH58p_22165 cb25e4f8751d1997d71fb4cdff0d5c09 208 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 69 87 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_28760 d3b7d5cc5f3aaf16975c8c3972c16c08 201 Pfam PF13417 Glutathione S-transferase, N-terminal domain 6 79 1.9E-16 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 TSH58p_28760 d3b7d5cc5f3aaf16975c8c3972c16c08 201 Gene3D G3DSA:3.40.30.10 4 193 3.6E-69 T 14-10-2018 TSH58p_28760 d3b7d5cc5f3aaf16975c8c3972c16c08 201 SUPERFAMILY SSF47616 71 199 9.26E-15 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily TSH58p_28760 d3b7d5cc5f3aaf16975c8c3972c16c08 201 SUPERFAMILY SSF52833 1 87 5.95E-17 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_28760 d3b7d5cc5f3aaf16975c8c3972c16c08 201 Gene3D G3DSA:1.20.1050.10 81 190 3.6E-69 T 14-10-2018 TSH58p_20605 98f5e293ec294a40a421da6a1f389f38 693 SUPERFAMILY SSF51445 330 674 1.22E-79 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_20605 98f5e293ec294a40a421da6a1f389f38 693 Gene3D G3DSA:2.60.60.40 9 128 9.5E-8 T 14-10-2018 TSH58p_20605 98f5e293ec294a40a421da6a1f389f38 693 Gene3D G3DSA:2.60.60.40 165 279 1.7E-8 T 14-10-2018 TSH58p_20605 98f5e293ec294a40a421da6a1f389f38 693 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 341 661 2.4E-61 T 14-10-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 TSH58p_20605 98f5e293ec294a40a421da6a1f389f38 693 Gene3D G3DSA:3.20.20.80 327 687 1.2E-117 T 14-10-2018 TSH58p_20605 98f5e293ec294a40a421da6a1f389f38 693 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 484 493 - T 14-10-2018 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 TSH58p_20605 98f5e293ec294a40a421da6a1f389f38 693 Pfam PF16841 Ca-dependent carbohydrate-binding module xylan-binding 168 259 4.7E-30 T 14-10-2018 IPR031768 Carbohydrate binding module, xylan-binding domain MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSH58p_20605 98f5e293ec294a40a421da6a1f389f38 693 Pfam PF16841 Ca-dependent carbohydrate-binding module xylan-binding 12 102 1.1E-26 T 14-10-2018 IPR031768 Carbohydrate binding module, xylan-binding domain MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSH58p_03030 ea7b6720d217b05aa7e1c396f5d8a289 337 SUPERFAMILY SSF53850 30 248 3.04E-29 T 14-10-2018 TSH58p_03030 ea7b6720d217b05aa7e1c396f5d8a289 337 Pfam PF13379 NMT1-like family 26 254 1.5E-29 T 14-10-2018 TSH58p_03030 ea7b6720d217b05aa7e1c396f5d8a289 337 Gene3D G3DSA:3.40.190.10 26 145 1.6E-8 T 14-10-2018 TSH58p_03030 ea7b6720d217b05aa7e1c396f5d8a289 337 Gene3D G3DSA:3.40.190.10 146 328 1.6E-29 T 14-10-2018 TSH58p_30850 cd339016bca992226ff775cf2f0bffe2 259 SUPERFAMILY SSF52540 12 253 3.25E-74 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_30850 cd339016bca992226ff775cf2f0bffe2 259 Pfam PF00005 ABC transporter 25 183 5.6E-36 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_30850 cd339016bca992226ff775cf2f0bffe2 259 PIRSF PIRSF039085 6 258 3.3E-104 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 TSH58p_30850 cd339016bca992226ff775cf2f0bffe2 259 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_30850 cd339016bca992226ff775cf2f0bffe2 259 Gene3D G3DSA:3.40.50.300 6 258 2.0E-74 T 14-10-2018 TSH58p_30850 cd339016bca992226ff775cf2f0bffe2 259 SMART SM00382 34 231 3.0E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_18600 5d8b961458f18bb8c891ffddcd0b7fb9 323 Gene3D G3DSA:3.40.190.150 31 313 1.3E-69 T 14-10-2018 TSH58p_18600 5d8b961458f18bb8c891ffddcd0b7fb9 323 SUPERFAMILY SSF53850 36 295 6.79E-9 T 14-10-2018 TSH58p_18600 5d8b961458f18bb8c891ffddcd0b7fb9 323 Gene3D G3DSA:3.40.190.10 125 249 1.3E-69 T 14-10-2018 TSH58p_18600 5d8b961458f18bb8c891ffddcd0b7fb9 323 PIRSF PIRSF017082 1 323 5.8E-94 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 TSH58p_18600 5d8b961458f18bb8c891ffddcd0b7fb9 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 320 5.0E-27 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 TSH58p_09955 40fb24fd57719a6cd30e536a66d8c069 155 Gene3D G3DSA:3.40.630.30 2 151 2.2E-38 T 14-10-2018 TSH58p_09955 40fb24fd57719a6cd30e536a66d8c069 155 Pfam PF00583 Acetyltransferase (GNAT) family 39 140 3.7E-15 T 14-10-2018 IPR000182 GNAT domain TSH58p_09955 40fb24fd57719a6cd30e536a66d8c069 155 SUPERFAMILY SSF55729 3 149 3.04E-29 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_16865 2742a05b5cf4d0b4f072146be879d3c1 338 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 69 123 1.0E-6 T 14-10-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 TSH58p_16865 2742a05b5cf4d0b4f072146be879d3c1 338 PIRSF PIRSF031982 11 336 1.3E-84 T 14-10-2018 IPR016986 Uncharacterised conserved protein UCP031982, alpha/beta hydrolase, XabL TSH58p_16865 2742a05b5cf4d0b4f072146be879d3c1 338 SUPERFAMILY SSF53474 35 331 4.99E-33 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_22410 9f3289ccae099021b6b3d9e121670109 125 Gene3D G3DSA:3.40.1230.10 9 125 8.7E-40 T 14-10-2018 IPR036748 MTH938-like superfamily TSH58p_22410 9f3289ccae099021b6b3d9e121670109 125 SUPERFAMILY SSF64076 3 125 3.53E-40 T 14-10-2018 IPR036748 MTH938-like superfamily TSH58p_22410 9f3289ccae099021b6b3d9e121670109 125 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 15 123 1.2E-32 T 14-10-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein TSH58p_12855 95636fe718663a10e0218074c76aba99 161 SMART SM00116 15 67 2.7E-7 T 14-10-2018 IPR000644 CBS domain TSH58p_12855 95636fe718663a10e0218074c76aba99 161 SMART SM00116 85 136 0.013 T 14-10-2018 IPR000644 CBS domain TSH58p_12855 95636fe718663a10e0218074c76aba99 161 Pfam PF00571 CBS domain 15 65 4.7E-8 T 14-10-2018 IPR000644 CBS domain TSH58p_12855 95636fe718663a10e0218074c76aba99 161 Pfam PF00571 CBS domain 79 134 2.9E-11 T 14-10-2018 IPR000644 CBS domain TSH58p_12855 95636fe718663a10e0218074c76aba99 161 SUPERFAMILY SSF54631 8 147 8.72E-28 T 14-10-2018 TSH58p_12855 95636fe718663a10e0218074c76aba99 161 Gene3D G3DSA:3.10.580.10 3 152 2.5E-36 T 14-10-2018 TSH58p_08295 f99a8e1ae63e552acabfe9c5fdc737eb 369 Gene3D G3DSA:3.40.50.2300 107 345 1.6E-55 T 14-10-2018 TSH58p_08295 f99a8e1ae63e552acabfe9c5fdc737eb 369 ProSitePatterns PS00356 LacI-type HTH domain signature. 46 64 - T 14-10-2018 TSH58p_08295 f99a8e1ae63e552acabfe9c5fdc737eb 369 SUPERFAMILY SSF53822 100 353 2.65E-48 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_08295 f99a8e1ae63e552acabfe9c5fdc737eb 369 Gene3D G3DSA:3.40.50.2300 201 329 1.6E-55 T 14-10-2018 TSH58p_08295 f99a8e1ae63e552acabfe9c5fdc737eb 369 SMART SM00354 43 113 5.4E-19 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TSH58p_08295 f99a8e1ae63e552acabfe9c5fdc737eb 369 Pfam PF13377 Periplasmic binding protein-like domain 210 369 6.9E-30 T 14-10-2018 TSH58p_08295 f99a8e1ae63e552acabfe9c5fdc737eb 369 Gene3D G3DSA:1.10.260.40 37 101 4.3E-18 T 14-10-2018 TSH58p_08295 f99a8e1ae63e552acabfe9c5fdc737eb 369 Pfam PF00356 Bacterial regulatory proteins, lacI family 46 90 8.7E-14 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TSH58p_08295 f99a8e1ae63e552acabfe9c5fdc737eb 369 SUPERFAMILY SSF47413 44 101 4.31E-15 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_30790 a8459ff181b970df40bb8642b5c26e06 224 Pfam PF03737 Aldolase/RraA 25 172 2.6E-38 T 14-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein TSH58p_30790 a8459ff181b970df40bb8642b5c26e06 224 Gene3D G3DSA:3.50.30.100 2 195 1.5E-54 T 14-10-2018 TSH58p_30790 a8459ff181b970df40bb8642b5c26e06 224 SUPERFAMILY SSF89562 22 182 1.01E-46 T 14-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily TSH58p_23475 5bf3d755382e1ffe5ef2c853a1ba668b 553 SUPERFAMILY SSF53474 280 521 1.33E-38 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_23475 5bf3d755382e1ffe5ef2c853a1ba668b 553 Pfam PF00756 Putative esterase 292 517 4.2E-25 T 14-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 TSH58p_23475 5bf3d755382e1ffe5ef2c853a1ba668b 553 Pfam PF11806 Domain of unknown function (DUF3327) 168 271 1.4E-19 T 14-10-2018 IPR021764 Enterochelin esterase, N-terminal GO:0005506|GO:0005737|GO:0006826|GO:0008849 TSH58p_23475 5bf3d755382e1ffe5ef2c853a1ba668b 553 Gene3D G3DSA:3.40.50.1820 263 523 1.5E-65 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_23475 5bf3d755382e1ffe5ef2c853a1ba668b 553 Gene3D G3DSA:2.60.40.10 132 257 6.2E-9 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_23475 5bf3d755382e1ffe5ef2c853a1ba668b 553 SUPERFAMILY SSF81296 135 268 2.66E-27 T 14-10-2018 IPR014756 Immunoglobulin E-set TSH58p_06595 195b11a7ce330ef7968437e421a1744b 134 Pfam PF06170 Protein of unknown function (DUF983) 41 124 1.7E-30 T 14-10-2018 IPR009325 Protein of unknown function DUF983 TSH58p_25170 af90c8a3411fe700b48f685941b520d7 561 SMART SM00304 316 369 5.1E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_25170 af90c8a3411fe700b48f685941b520d7 561 SMART SM00267 367 537 7.8E-63 T 14-10-2018 IPR000160 GGDEF domain TSH58p_25170 af90c8a3411fe700b48f685941b520d7 561 Gene3D G3DSA:3.30.450.20 81 185 4.0E-17 T 14-10-2018 TSH58p_25170 af90c8a3411fe700b48f685941b520d7 561 Gene3D G3DSA:3.30.70.270 373 537 2.7E-55 T 14-10-2018 TSH58p_25170 af90c8a3411fe700b48f685941b520d7 561 SUPERFAMILY SSF55073 383 535 6.91E-48 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_25170 af90c8a3411fe700b48f685941b520d7 561 Gene3D G3DSA:1.20.1480.50 284 372 6.2E-8 T 14-10-2018 TSH58p_25170 af90c8a3411fe700b48f685941b520d7 561 SUPERFAMILY SSF158472 317 365 7.98E-6 T 14-10-2018 TSH58p_25170 af90c8a3411fe700b48f685941b520d7 561 Pfam PF00672 HAMP domain 317 365 1.1E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_25170 af90c8a3411fe700b48f685941b520d7 561 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 374 533 1.4E-40 T 14-10-2018 IPR000160 GGDEF domain TSH58p_25170 af90c8a3411fe700b48f685941b520d7 561 Pfam PF00990 Diguanylate cyclase, GGDEF domain 378 533 1.9E-45 T 14-10-2018 IPR000160 GGDEF domain TSH58p_22420 c21fd7d764f9a412fa3630830cc47109 123 SMART SM01323 19 102 1.0E-41 T 14-10-2018 IPR003849 Preprotein translocase YajC TSH58p_22420 c21fd7d764f9a412fa3630830cc47109 123 PRINTS PR01853 Bacterial YajC preprotein translocase signature 21 41 1.3E-17 T 14-10-2018 IPR003849 Preprotein translocase YajC TSH58p_22420 c21fd7d764f9a412fa3630830cc47109 123 PRINTS PR01853 Bacterial YajC preprotein translocase signature 59 77 1.3E-17 T 14-10-2018 IPR003849 Preprotein translocase YajC TSH58p_22420 c21fd7d764f9a412fa3630830cc47109 123 Pfam PF02699 Preprotein translocase subunit 23 98 9.8E-30 T 14-10-2018 IPR003849 Preprotein translocase YajC TSH58p_22420 c21fd7d764f9a412fa3630830cc47109 123 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 20 102 3.4E-28 T 14-10-2018 IPR003849 Preprotein translocase YajC TSH58p_16750 76db18acbbe4a503b8055e9b4d1b5b11 493 SUPERFAMILY SSF141571 240 372 1.44E-26 T 14-10-2018 TSH58p_16750 76db18acbbe4a503b8055e9b4d1b5b11 493 Gene3D G3DSA:2.160.20.100 128 215 1.8E-18 T 14-10-2018 TSH58p_16750 76db18acbbe4a503b8055e9b4d1b5b11 493 SUPERFAMILY SSF141571 29 205 1.18E-39 T 14-10-2018 TSH58p_16750 76db18acbbe4a503b8055e9b4d1b5b11 493 Pfam PF07238 PilZ domain 390 482 4.2E-5 T 14-10-2018 IPR009875 PilZ domain GO:0035438 TSH58p_16750 76db18acbbe4a503b8055e9b4d1b5b11 493 Pfam PF00805 Pentapeptide repeats (8 copies) 133 170 6.1E-11 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_16750 76db18acbbe4a503b8055e9b4d1b5b11 493 Pfam PF00805 Pentapeptide repeats (8 copies) 29 63 3.5E-6 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_16750 76db18acbbe4a503b8055e9b4d1b5b11 493 Pfam PF00805 Pentapeptide repeats (8 copies) 267 306 4.1E-9 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_16750 76db18acbbe4a503b8055e9b4d1b5b11 493 Pfam PF00805 Pentapeptide repeats (8 copies) 337 372 6.1E-10 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_16750 76db18acbbe4a503b8055e9b4d1b5b11 493 Pfam PF00805 Pentapeptide repeats (8 copies) 76 114 2.3E-12 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_16750 76db18acbbe4a503b8055e9b4d1b5b11 493 Gene3D G3DSA:2.160.20.80 222 377 8.0E-30 T 14-10-2018 TSH58p_16750 76db18acbbe4a503b8055e9b4d1b5b11 493 Gene3D G3DSA:2.160.20.80 11 115 3.0E-25 T 14-10-2018 TSH58p_14295 2a485f3e19ace08568110e62b46332a8 320 Gene3D G3DSA:3.10.20.310 98 166 1.2E-6 T 14-10-2018 TSH58p_14295 2a485f3e19ace08568110e62b46332a8 320 Pfam PF03799 Cell division protein FtsQ 171 290 5.3E-19 T 14-10-2018 IPR005548 Cell division protein FtsQ/DivIB TSH58p_14295 2a485f3e19ace08568110e62b46332a8 320 Pfam PF08478 POTRA domain, FtsQ-type 99 167 1.0E-16 T 14-10-2018 IPR013685 POTRA domain, FtsQ-type TSH58p_14295 2a485f3e19ace08568110e62b46332a8 320 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 70 308 19.275 T 14-10-2018 IPR026579 Cell division protein FtsQ GO:0090529 TSH58p_16275 03a4efa64e91cc0597ec1c9840c59f3e 250 Gene3D G3DSA:3.30.70.980 134 206 4.6E-50 T 14-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16275 03a4efa64e91cc0597ec1c9840c59f3e 250 Gene3D G3DSA:1.10.10.200 1 82 1.4E-31 T 14-10-2018 IPR017856 Integrase-like, N-terminal TSH58p_16275 03a4efa64e91cc0597ec1c9840c59f3e 250 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 238 3.4E-94 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16275 03a4efa64e91cc0597ec1c9840c59f3e 250 Gene3D G3DSA:3.30.70.980 85 235 4.6E-50 T 14-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16275 03a4efa64e91cc0597ec1c9840c59f3e 250 SUPERFAMILY SSF75625 3 247 1.09E-88 T 14-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16275 03a4efa64e91cc0597ec1c9840c59f3e 250 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 240 33.639 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16275 03a4efa64e91cc0597ec1c9840c59f3e 250 Pfam PF01709 Transcriptional regulator 5 237 2.4E-89 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_09560 240f146a948e557675a5320c5d6f75ca 378 Pfam PF05036 Sporulation related domain 301 375 1.9E-16 T 14-10-2018 IPR007730 Sporulation-like domain GO:0042834 TSH58p_09560 240f146a948e557675a5320c5d6f75ca 378 SUPERFAMILY SSF110997 300 367 1.7E-14 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 TSH58p_09560 240f146a948e557675a5320c5d6f75ca 378 Gene3D G3DSA:3.30.70.1070 301 376 7.5E-12 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 TSH58p_15315 c865691b3c7f383f7d20357689bcf899 135 Gene3D G3DSA:1.10.8.930 1 130 1.3E-44 T 14-10-2018 IPR038301 AraC-like superfamily TSH58p_15315 c865691b3c7f383f7d20357689bcf899 135 Pfam PF07323 Protein of unknown function (DUF1465) 4 130 2.8E-31 T 14-10-2018 IPR010848 Protein of unknown function DUF1465 TSH58p_31885 63ba58f9f8456176ade26e83d18612ec 251 SUPERFAMILY SSF46785 4 75 3.92E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_31885 63ba58f9f8456176ade26e83d18612ec 251 Gene3D G3DSA:1.10.10.10 1 53 1.6E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_31885 63ba58f9f8456176ade26e83d18612ec 251 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 1.5E-13 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TSH58p_31885 63ba58f9f8456176ade26e83d18612ec 251 SMART SM00420 6 58 1.9E-10 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TSH58p_31885 63ba58f9f8456176ade26e83d18612ec 251 Pfam PF00455 DeoR C terminal sensor domain 76 231 1.0E-47 T 14-10-2018 IPR014036 DeoR C-terminal sensor domain TSH58p_31885 63ba58f9f8456176ade26e83d18612ec 251 SUPERFAMILY SSF100950 75 232 9.07E-30 T 14-10-2018 IPR037171 NagB/RpiA transferase-like TSH58p_31885 63ba58f9f8456176ade26e83d18612ec 251 SMART SM01134 72 233 4.1E-63 T 14-10-2018 TSH58p_31885 63ba58f9f8456176ade26e83d18612ec 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 5.1E-7 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TSH58p_31885 63ba58f9f8456176ade26e83d18612ec 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 5.1E-7 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TSH58p_31885 63ba58f9f8456176ade26e83d18612ec 251 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 TSH58p_15115 cedb1aacda697e2caa8888ada48fd760 172 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 39 155 0.002 T 14-10-2018 TSH58p_15115 cedb1aacda697e2caa8888ada48fd760 172 ProSitePatterns PS01109 Ribosomal protein L10 signature. 6 40 - T 14-10-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15115 cedb1aacda697e2caa8888ada48fd760 172 SUPERFAMILY SSF160369 3 168 2.48E-56 T 14-10-2018 TSH58p_15115 cedb1aacda697e2caa8888ada48fd760 172 Pfam PF00466 Ribosomal protein L10 3 98 2.5E-24 T 14-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 TSH58p_15115 cedb1aacda697e2caa8888ada48fd760 172 Gene3D G3DSA:3.30.70.1730 1 131 4.6E-40 T 14-10-2018 TSH58p_15115 cedb1aacda697e2caa8888ada48fd760 172 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 158 25.685 T 14-10-2018 IPR022973 Ribosomal protein L10 TSH58p_10910 c8fdff71ac31df8df8ef4843ecbdff56 291 SUPERFAMILY SSF56281 22 291 4.72E-52 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_10910 c8fdff71ac31df8df8ef4843ecbdff56 291 SMART SM00849 44 234 1.2E-8 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_10910 c8fdff71ac31df8df8ef4843ecbdff56 291 Pfam PF12706 Beta-lactamase superfamily domain 58 257 8.2E-29 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_10910 c8fdff71ac31df8df8ef4843ecbdff56 291 Gene3D G3DSA:3.60.15.10 21 291 2.9E-48 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_09855 da20f395fd758db2e212347901bf9449 1618 SUPERFAMILY SSF51735 958 1294 2.69E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_09855 da20f395fd758db2e212347901bf9449 1618 PIRSF PIRSF036761 2 1618 0.0 T 14-10-2018 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 TSH58p_09855 da20f395fd758db2e212347901bf9449 1618 SUPERFAMILY SSF53223 766 953 5.95E-23 T 14-10-2018 TSH58p_09855 da20f395fd758db2e212347901bf9449 1618 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 78 1613 0.0 T 14-10-2018 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 TSH58p_30325 ad0a89f7d2154302f65b20369e8109eb 65 Pfam PF02416 mttA/Hcf106 family 5 49 1.1E-11 T 14-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 TSH58p_30325 ad0a89f7d2154302f65b20369e8109eb 65 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 48 6.2E-20 T 14-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 TSH58p_30325 ad0a89f7d2154302f65b20369e8109eb 65 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 64 19.949 T 14-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 TSH58p_05580 d5d537352f844c60c6e25f39d4c2409f 232 Gene3D G3DSA:3.40.50.1820 1 230 1.2E-63 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_05580 d5d537352f844c60c6e25f39d4c2409f 232 SUPERFAMILY SSF53474 2 232 4.75E-55 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_05580 d5d537352f844c60c6e25f39d4c2409f 232 Pfam PF01738 Dienelactone hydrolase family 14 230 2.8E-54 T 14-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 TSH58p_19295 cc30d229333497a7c91bb74a99eed0f8 213 Hamap MF_01207 Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ [msrQ]. 13 208 20.463 T 14-10-2018 IPR022837 Protein-methionine-sulfoxide reductase subunit MsrQ GO:0005887|GO:0030091 TSH58p_19295 cc30d229333497a7c91bb74a99eed0f8 213 Pfam PF01794 Ferric reductase like transmembrane component 55 166 1.2E-18 T 14-10-2018 IPR013130 Ferric reductase transmembrane component-like domain TSH58p_14780 0f500203162d8b5e7b42b0ed8de0b5ab 384 SUPERFAMILY SSF53383 12 382 9.08E-100 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_14780 0f500203162d8b5e7b42b0ed8de0b5ab 384 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 95 115 1.2E-12 T 14-10-2018 TSH58p_14780 0f500203162d8b5e7b42b0ed8de0b5ab 384 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 117 138 1.2E-12 T 14-10-2018 TSH58p_14780 0f500203162d8b5e7b42b0ed8de0b5ab 384 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 163 187 1.2E-12 T 14-10-2018 TSH58p_14780 0f500203162d8b5e7b42b0ed8de0b5ab 384 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 199 222 1.2E-12 T 14-10-2018 TSH58p_14780 0f500203162d8b5e7b42b0ed8de0b5ab 384 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 231 244 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TSH58p_14780 0f500203162d8b5e7b42b0ed8de0b5ab 384 Pfam PF00155 Aminotransferase class I and II 35 379 3.3E-58 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSH58p_14780 0f500203162d8b5e7b42b0ed8de0b5ab 384 Gene3D G3DSA:3.40.640.10 5 384 2.8E-133 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_29865 3589c2443016e7a79ddf91586ae34414 123 Gene3D G3DSA:3.10.129.10 2 123 9.6E-39 T 14-10-2018 TSH58p_29865 3589c2443016e7a79ddf91586ae34414 123 Pfam PF03061 Thioesterase superfamily 19 90 2.2E-17 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TSH58p_29865 3589c2443016e7a79ddf91586ae34414 123 SUPERFAMILY SSF54637 5 122 8.57E-39 T 14-10-2018 IPR029069 HotDog domain superfamily TSH58p_31180 be3d8ab07704120d8c325a790b49727a 240 Gene3D G3DSA:3.40.50.300 1 237 1.3E-61 T 14-10-2018 TSH58p_31180 be3d8ab07704120d8c325a790b49727a 240 SMART SM00382 27 230 9.0E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_31180 be3d8ab07704120d8c325a790b49727a 240 Pfam PF00005 ABC transporter 18 164 9.9E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_31180 be3d8ab07704120d8c325a790b49727a 240 SUPERFAMILY SSF52540 2 234 3.63E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_30345 cc4587e813ae96e180ec1ea47e778072 289 Pfam PF00005 ABC transporter 23 163 1.8E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_30345 cc4587e813ae96e180ec1ea47e778072 289 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_30345 cc4587e813ae96e180ec1ea47e778072 289 Gene3D G3DSA:3.40.50.300 1 228 3.4E-64 T 14-10-2018 TSH58p_30345 cc4587e813ae96e180ec1ea47e778072 289 SUPERFAMILY SSF52540 5 223 8.04E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_30345 cc4587e813ae96e180ec1ea47e778072 289 SMART SM00382 31 212 5.9E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_08575 6d724f12041a993f04403b87e2c071c0 245 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 124 141 5.2E-4 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_08575 6d724f12041a993f04403b87e2c071c0 245 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 89 105 0.0022 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_08575 6d724f12041a993f04403b87e2c071c0 245 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 107 123 6.4E-4 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_08575 6d724f12041a993f04403b87e2c071c0 245 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 160 176 8.9E-4 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_08575 6d724f12041a993f04403b87e2c071c0 245 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 142 159 7.8E-4 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_08575 6d724f12041a993f04403b87e2c071c0 245 SUPERFAMILY SSF55486 14 70 5.43E-5 T 14-10-2018 TSH58p_08575 6d724f12041a993f04403b87e2c071c0 245 SUPERFAMILY SSF51120 83 234 6.06E-36 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_08575 6d724f12041a993f04403b87e2c071c0 245 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 157 175 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_08575 6d724f12041a993f04403b87e2c071c0 245 Gene3D G3DSA:2.150.10.10 130 243 6.7E-28 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_08575 6d724f12041a993f04403b87e2c071c0 245 Gene3D G3DSA:2.150.10.10 83 129 2.5E-13 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_08575 6d724f12041a993f04403b87e2c071c0 245 PRINTS PR00313 NodO calcium binding signature 116 124 1.0E-12 T 14-10-2018 TSH58p_08575 6d724f12041a993f04403b87e2c071c0 245 PRINTS PR00313 NodO calcium binding signature 143 151 1.0E-12 T 14-10-2018 TSH58p_08575 6d724f12041a993f04403b87e2c071c0 245 PRINTS PR00313 NodO calcium binding signature 95 106 1.0E-12 T 14-10-2018 TSH58p_08575 6d724f12041a993f04403b87e2c071c0 245 PRINTS PR00313 NodO calcium binding signature 170 179 1.0E-12 T 14-10-2018 TSH58p_01750 8e7fc82d13a76e2010a5dc579edddd62 256 SUPERFAMILY SSF52096 2 253 9.27E-68 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_01750 8e7fc82d13a76e2010a5dc579edddd62 256 Gene3D G3DSA:3.90.226.10 4 230 4.6E-67 T 14-10-2018 TSH58p_01750 8e7fc82d13a76e2010a5dc579edddd62 256 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 252 1.2E-44 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TSH58p_16410 67e470be8703f22c39fbe4aa3bb1c6db 181 SUPERFAMILY SSF57997 24 88 8.83E-7 T 14-10-2018 TSH58p_04005 ab0661b7f417947717308b5bff067d7f 263 Pfam PF00005 ABC transporter 27 176 8.5E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_04005 ab0661b7f417947717308b5bff067d7f 263 Gene3D G3DSA:3.40.50.300 11 260 1.9E-65 T 14-10-2018 TSH58p_04005 ab0661b7f417947717308b5bff067d7f 263 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_04005 ab0661b7f417947717308b5bff067d7f 263 SUPERFAMILY SSF52540 12 239 2.6E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_04005 ab0661b7f417947717308b5bff067d7f 263 SMART SM00382 36 226 2.4E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_13895 21bbc36b34e4e7f1c1ab1959c0a9ec57 583 SMART SM00564 284 311 23.0 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSH58p_13895 21bbc36b34e4e7f1c1ab1959c0a9ec57 583 SMART SM00564 91 122 8.1E-5 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSH58p_13895 21bbc36b34e4e7f1c1ab1959c0a9ec57 583 SMART SM00564 140 171 7.8E-5 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSH58p_13895 21bbc36b34e4e7f1c1ab1959c0a9ec57 583 SMART SM00564 442 484 0.036 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSH58p_13895 21bbc36b34e4e7f1c1ab1959c0a9ec57 583 SMART SM00564 493 525 2.0E-5 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSH58p_13895 21bbc36b34e4e7f1c1ab1959c0a9ec57 583 SMART SM00564 185 222 0.11 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSH58p_13895 21bbc36b34e4e7f1c1ab1959c0a9ec57 583 SUPERFAMILY SSF50998 35 576 1.44E-168 T 14-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TSH58p_13895 21bbc36b34e4e7f1c1ab1959c0a9ec57 583 Pfam PF13360 PQQ-like domain 74 309 4.0E-20 T 14-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat TSH58p_13895 21bbc36b34e4e7f1c1ab1959c0a9ec57 583 TIGRFAM TIGR03075 PQQ_enz_alc_DH: PQQ-dependent dehydrogenase, methanol/ethanol family 31 553 5.2E-244 T 14-10-2018 IPR017512 PQQ-dependent dehydrogenase, methanol/ethanol family GO:0005509|GO:0016020|GO:0016614|GO:0055114 TSH58p_13895 21bbc36b34e4e7f1c1ab1959c0a9ec57 583 Pfam PF01011 PQQ enzyme repeat 499 535 2.9E-10 T 14-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat TSH58p_13895 21bbc36b34e4e7f1c1ab1959c0a9ec57 583 Gene3D G3DSA:2.140.10.10 31 583 3.0E-224 T 14-10-2018 TSH58p_05645 b26de1765181bd48551ac912aa4fdd4d 153 Pfam PF00583 Acetyltransferase (GNAT) family 36 131 8.9E-16 T 14-10-2018 IPR000182 GNAT domain TSH58p_05645 b26de1765181bd48551ac912aa4fdd4d 153 Gene3D G3DSA:3.40.630.30 3 153 1.9E-43 T 14-10-2018 TSH58p_05645 b26de1765181bd48551ac912aa4fdd4d 153 SUPERFAMILY SSF55729 15 153 7.67E-26 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_14535 93a4a13668833a357f3435d428ad4e96 248 PIRSF PIRSF030013 5 244 4.4E-105 T 14-10-2018 IPR009381 Trehalose catabolism protein, ThuA, prokaryote TSH58p_14535 93a4a13668833a357f3435d428ad4e96 248 SUPERFAMILY SSF52317 6 236 4.12E-60 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_14535 93a4a13668833a357f3435d428ad4e96 248 Gene3D G3DSA:3.40.50.880 4 244 3.9E-102 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_14535 93a4a13668833a357f3435d428ad4e96 248 Pfam PF06283 Trehalose utilisation 7 223 2.3E-30 T 14-10-2018 IPR029010 ThuA-like domain TSH58p_13120 ef9137b3144ae8aa89d23750fe28ff2f 563 SUPERFAMILY SSF55785 101 220 2.44E-11 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_13120 ef9137b3144ae8aa89d23750fe28ff2f 563 Gene3D G3DSA:3.30.450.20 101 237 1.8E-9 T 14-10-2018 TSH58p_13120 ef9137b3144ae8aa89d23750fe28ff2f 563 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 114 165 5.8E-6 T 14-10-2018 IPR000014 PAS domain TSH58p_13120 ef9137b3144ae8aa89d23750fe28ff2f 563 SMART SM00267 375 545 1.4E-54 T 14-10-2018 IPR000160 GGDEF domain TSH58p_13120 ef9137b3144ae8aa89d23750fe28ff2f 563 Pfam PF00990 Diguanylate cyclase, GGDEF domain 388 540 2.7E-38 T 14-10-2018 IPR000160 GGDEF domain TSH58p_13120 ef9137b3144ae8aa89d23750fe28ff2f 563 Gene3D G3DSA:3.30.70.270 380 545 7.4E-50 T 14-10-2018 TSH58p_13120 ef9137b3144ae8aa89d23750fe28ff2f 563 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 383 544 7.1E-41 T 14-10-2018 IPR000160 GGDEF domain TSH58p_13120 ef9137b3144ae8aa89d23750fe28ff2f 563 SUPERFAMILY SSF55781 236 375 5.89E-8 T 14-10-2018 TSH58p_13120 ef9137b3144ae8aa89d23750fe28ff2f 563 SUPERFAMILY SSF55073 391 544 2.59E-42 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_13120 ef9137b3144ae8aa89d23750fe28ff2f 563 Gene3D G3DSA:3.30.450.40 240 379 1.2E-7 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_15280 adfc9d0a48032cb995460f92991fb364 304 SUPERFAMILY SSF103481 203 303 6.28E-12 T 14-10-2018 TSH58p_15280 adfc9d0a48032cb995460f92991fb364 304 Pfam PF00892 EamA-like transporter family 166 299 8.2E-19 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_15280 adfc9d0a48032cb995460f92991fb364 304 Pfam PF00892 EamA-like transporter family 20 153 6.1E-13 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_15280 adfc9d0a48032cb995460f92991fb364 304 SUPERFAMILY SSF103481 51 157 8.63E-15 T 14-10-2018 TSH58p_11930 11d022083a3090602de0793c0b55df04 319 Pfam PF08239 Bacterial SH3 domain 54 103 2.2E-6 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type TSH58p_11930 11d022083a3090602de0793c0b55df04 319 Gene3D G3DSA:2.30.30.40 43 106 2.9E-6 T 14-10-2018 TSH58p_16150 2fb79f13765bc43d6380855dd2966f4d 370 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 8 364 2.8E-108 T 14-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 TSH58p_16150 2fb79f13765bc43d6380855dd2966f4d 370 Gene3D G3DSA:4.10.1250.10 236 280 1.4E-22 T 14-10-2018 TSH58p_16150 2fb79f13765bc43d6380855dd2966f4d 370 Gene3D G3DSA:3.30.70.1400 59 143 2.7E-81 T 14-10-2018 TSH58p_16150 2fb79f13765bc43d6380855dd2966f4d 370 Pfam PF01571 Aminomethyltransferase folate-binding domain 13 258 7.6E-88 T 14-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain TSH58p_16150 2fb79f13765bc43d6380855dd2966f4d 370 Gene3D G3DSA:2.40.30.110 282 359 3.4E-29 T 14-10-2018 TSH58p_16150 2fb79f13765bc43d6380855dd2966f4d 370 SUPERFAMILY SSF101790 276 369 1.16E-26 T 14-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal TSH58p_16150 2fb79f13765bc43d6380855dd2966f4d 370 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 267 360 3.6E-25 T 14-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 TSH58p_16150 2fb79f13765bc43d6380855dd2966f4d 370 PIRSF PIRSF006487 2 370 3.0E-87 T 14-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 TSH58p_16150 2fb79f13765bc43d6380855dd2966f4d 370 SUPERFAMILY SSF103025 7 283 2.13E-90 T 14-10-2018 TSH58p_16150 2fb79f13765bc43d6380855dd2966f4d 370 Gene3D G3DSA:3.30.1360.120 12 234 2.7E-81 T 14-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 TSH58p_10825 a2ad8a2bf2ac4ef1158fac5590ee54ee 227 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 25 226 1.6E-54 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 TSH58p_10825 a2ad8a2bf2ac4ef1158fac5590ee54ee 227 SUPERFAMILY SSF56529 20 226 1.31E-73 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TSH58p_10825 a2ad8a2bf2ac4ef1158fac5590ee54ee 227 Gene3D G3DSA:3.90.850.10 11 227 1.7E-90 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TSH58p_08030 e4a4ebb9246105a7e55be43e931a9c60 252 Pfam PF00227 Proteasome subunit 4 179 1.7E-7 T 14-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TSH58p_08030 e4a4ebb9246105a7e55be43e931a9c60 252 PIRSF PIRSF009120 1 243 4.8E-58 T 14-10-2018 IPR016545 Uncharacterised conserved protein UCP009120, proteasome-type protease, Sll0069 TSH58p_08030 e4a4ebb9246105a7e55be43e931a9c60 252 SUPERFAMILY SSF56235 2 231 2.58E-21 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_08030 e4a4ebb9246105a7e55be43e931a9c60 252 Gene3D G3DSA:3.60.20.10 2 226 2.0E-17 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_12900 df1700d903b1e199be9882f7278414a8 180 SUPERFAMILY SSF161084 64 178 2.49E-11 T 14-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily TSH58p_12900 df1700d903b1e199be9882f7278414a8 180 Pfam PF01124 MAPEG family 65 175 2.3E-9 T 14-10-2018 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein TSH58p_12900 df1700d903b1e199be9882f7278414a8 180 Gene3D G3DSA:1.20.120.550 53 180 1.1E-12 T 14-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily TSH58p_24215 9f623c091f744819f8bd213e00c496f5 230 PIRSF PIRSF001435 24 229 1.5E-34 T 14-10-2018 TSH58p_24215 9f623c091f744819f8bd213e00c496f5 230 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 52 186 1.1E-18 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TSH58p_24215 9f623c091f744819f8bd213e00c496f5 230 Gene3D G3DSA:1.10.340.30 43 150 5.8E-49 T 14-10-2018 TSH58p_24215 9f623c091f744819f8bd213e00c496f5 230 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 205 221 - T 14-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 TSH58p_24215 9f623c091f744819f8bd213e00c496f5 230 SUPERFAMILY SSF48150 37 222 4.08E-54 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TSH58p_24215 9f623c091f744819f8bd213e00c496f5 230 Gene3D G3DSA:1.10.1670.10 151 221 5.8E-49 T 14-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 TSH58p_24215 9f623c091f744819f8bd213e00c496f5 230 SMART SM00478 56 203 3.6E-41 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TSH58p_02095 8bd50b77e70848b4f3e5f6b80c98efb2 453 PRINTS PR00095 Anthranilate synthase component I signature 288 301 3.2E-16 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TSH58p_02095 8bd50b77e70848b4f3e5f6b80c98efb2 453 PRINTS PR00095 Anthranilate synthase component I signature 397 411 3.2E-16 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TSH58p_02095 8bd50b77e70848b4f3e5f6b80c98efb2 453 PRINTS PR00095 Anthranilate synthase component I signature 302 315 3.2E-16 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TSH58p_02095 8bd50b77e70848b4f3e5f6b80c98efb2 453 PRINTS PR00095 Anthranilate synthase component I signature 382 396 3.2E-16 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TSH58p_02095 8bd50b77e70848b4f3e5f6b80c98efb2 453 Pfam PF00425 chorismate binding enzyme 183 440 8.1E-92 T 14-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal TSH58p_02095 8bd50b77e70848b4f3e5f6b80c98efb2 453 Pfam PF04715 Anthranilate synthase component I, N terminal region 10 142 9.3E-26 T 14-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TSH58p_02095 8bd50b77e70848b4f3e5f6b80c98efb2 453 SUPERFAMILY SSF56322 5 449 3.4E-136 T 14-10-2018 IPR005801 ADC synthase GO:0009058 TSH58p_02095 8bd50b77e70848b4f3e5f6b80c98efb2 453 Gene3D G3DSA:3.60.120.10 2 453 2.4E-153 T 14-10-2018 IPR005801 ADC synthase GO:0009058 TSH58p_02095 8bd50b77e70848b4f3e5f6b80c98efb2 453 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 96 442 1.2E-105 T 14-10-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 TSH58p_29145 faa497a873cf1d54567f8e80be1b4068 347 Gene3D G3DSA:3.40.50.2000 154 292 1.2E-26 T 14-10-2018 TSH58p_29145 faa497a873cf1d54567f8e80be1b4068 347 TIGRFAM TIGR03590 PseG: UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase 2 281 5.1E-55 T 14-10-2018 IPR020023 UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase TSH58p_29145 faa497a873cf1d54567f8e80be1b4068 347 SUPERFAMILY SSF53756 164 343 1.19E-12 T 14-10-2018 TSH58p_29145 faa497a873cf1d54567f8e80be1b4068 347 Gene3D G3DSA:3.40.50.11190 1 153 4.3E-19 T 14-10-2018 TSH58p_29145 faa497a873cf1d54567f8e80be1b4068 347 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 227 323 3.7E-6 T 14-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 TSH58p_25515 1158ef620c944ccd067d6ef4829f3742 323 Pfam PF04796 Plasmid encoded RepA protein 95 258 7.8E-45 T 14-10-2018 IPR006881 Plasmid encoded RepA protein TSH58p_03195 1ba7b744bc73620aaa60c89bde3983eb 376 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 258 276 5.3E-5 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_03195 1ba7b744bc73620aaa60c89bde3983eb 376 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 33 49 5.3E-5 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_03195 1ba7b744bc73620aaa60c89bde3983eb 376 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 55 71 5.3E-5 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_03195 1ba7b744bc73620aaa60c89bde3983eb 376 SUPERFAMILY SSF53822 31 374 1.24E-87 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_03195 1ba7b744bc73620aaa60c89bde3983eb 376 Gene3D G3DSA:3.40.50.2300 148 282 2.2E-99 T 14-10-2018 TSH58p_03195 1ba7b744bc73620aaa60c89bde3983eb 376 Pfam PF13458 Periplasmic binding protein 32 369 1.0E-60 T 14-10-2018 IPR028081 Leucine-binding protein domain TSH58p_03195 1ba7b744bc73620aaa60c89bde3983eb 376 Gene3D G3DSA:3.40.50.2300 36 351 2.2E-99 T 14-10-2018 TSH58p_24515 902660d4520e7f874270abe3753650b9 254 SUPERFAMILY SSF53448 1 209 1.9E-32 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_24515 902660d4520e7f874270abe3753650b9 254 Gene3D G3DSA:3.90.550.10 2 222 7.4E-25 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_24515 902660d4520e7f874270abe3753650b9 254 Pfam PF00535 Glycosyl transferase family 2 8 117 7.0E-19 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_23430 342a6ce42e234f66f57c618a02e56426 417 SUPERFAMILY SSF103473 19 397 4.84E-38 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_23430 342a6ce42e234f66f57c618a02e56426 417 Pfam PF07690 Major Facilitator Superfamily 23 355 1.3E-24 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_23430 342a6ce42e234f66f57c618a02e56426 417 Gene3D G3DSA:1.20.1250.20 18 403 1.6E-32 T 14-10-2018 TSH58p_17840 34bb91c305679962773d8c9e2c245ae1 480 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 10 479 8.9E-210 T 14-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 TSH58p_17840 34bb91c305679962773d8c9e2c245ae1 480 Pfam PF01050 Mannose-6-phosphate isomerase 325 475 3.4E-70 T 14-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 TSH58p_17840 34bb91c305679962773d8c9e2c245ae1 480 Gene3D G3DSA:2.60.120.10 370 471 5.4E-19 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_17840 34bb91c305679962773d8c9e2c245ae1 480 Gene3D G3DSA:3.90.550.10 8 361 2.0E-113 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_17840 34bb91c305679962773d8c9e2c245ae1 480 Pfam PF00483 Nucleotidyl transferase 12 294 3.6E-65 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TSH58p_17840 34bb91c305679962773d8c9e2c245ae1 480 SUPERFAMILY SSF51182 194 479 3.35E-86 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_17840 34bb91c305679962773d8c9e2c245ae1 480 SUPERFAMILY SSF53448 10 290 3.92E-70 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_24910 48210c7a80156b6dd161e2cdaf0d3915 672 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 566 2.1E-143 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 TSH58p_24910 48210c7a80156b6dd161e2cdaf0d3915 672 Pfam PF13537 Glutamine amidotransferase domain 48 165 1.5E-40 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain TSH58p_24910 48210c7a80156b6dd161e2cdaf0d3915 672 Gene3D G3DSA:3.60.20.10 4 184 1.5E-57 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_24910 48210c7a80156b6dd161e2cdaf0d3915 672 Pfam PF00733 Asparagine synthase 244 633 2.3E-84 T 14-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 TSH58p_24910 48210c7a80156b6dd161e2cdaf0d3915 672 SUPERFAMILY SSF52402 220 603 1.94E-64 T 14-10-2018 TSH58p_24910 48210c7a80156b6dd161e2cdaf0d3915 672 SUPERFAMILY SSF56235 1 224 2.32E-56 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_24910 48210c7a80156b6dd161e2cdaf0d3915 672 PIRSF PIRSF001589 1 651 9.0E-157 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 TSH58p_29790 426c340d0c5fd1dd547c8a0ffc3794b7 886 Gene3D G3DSA:3.30.200.20 568 711 5.1E-58 T 14-10-2018 TSH58p_29790 426c340d0c5fd1dd547c8a0ffc3794b7 886 SUPERFAMILY SSF56112 599 877 1.75E-50 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily TSH58p_29790 426c340d0c5fd1dd547c8a0ffc3794b7 886 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 749 761 - T 14-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 TSH58p_29790 426c340d0c5fd1dd547c8a0ffc3794b7 886 Pfam PF00069 Protein kinase domain 611 829 2.6E-31 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TSH58p_29790 426c340d0c5fd1dd547c8a0ffc3794b7 886 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 615 638 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TSH58p_29790 426c340d0c5fd1dd547c8a0ffc3794b7 886 Gene3D G3DSA:1.10.510.10 712 879 5.1E-58 T 14-10-2018 TSH58p_11455 0b13339b346fdc951427fb06a6e97418 471 Gene3D G3DSA:3.20.20.70 20 471 1.5E-23 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_11455 0b13339b346fdc951427fb06a6e97418 471 SUPERFAMILY SSF51412 31 315 1.89E-7 T 14-10-2018 TSH58p_03975 102f3847fe6f502a7030a02149cc8d05 482 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 16 462 6.8E-158 T 14-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 TSH58p_03975 102f3847fe6f502a7030a02149cc8d05 482 Gene3D G3DSA:3.60.20.10 16 463 1.0E-157 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_03975 102f3847fe6f502a7030a02149cc8d05 482 Pfam PF00156 Phosphoribosyl transferase domain 269 385 4.0E-11 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TSH58p_03975 102f3847fe6f502a7030a02149cc8d05 482 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 15 461 46.325 T 14-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 TSH58p_03975 102f3847fe6f502a7030a02149cc8d05 482 PIRSF PIRSF000485 12 477 8.8E-171 T 14-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 TSH58p_03975 102f3847fe6f502a7030a02149cc8d05 482 Gene3D G3DSA:3.40.50.2020 275 439 1.0E-157 T 14-10-2018 TSH58p_03975 102f3847fe6f502a7030a02149cc8d05 482 SUPERFAMILY SSF56235 16 257 2.32E-66 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_03975 102f3847fe6f502a7030a02149cc8d05 482 SUPERFAMILY SSF53271 250 469 6.46E-77 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like TSH58p_03975 102f3847fe6f502a7030a02149cc8d05 482 Pfam PF13522 Glutamine amidotransferase domain 82 209 2.2E-19 T 14-10-2018 TSH58p_18910 2fd36d6803e288ff03bd88d0703240b5 279 Gene3D G3DSA:3.40.1280.10 119 276 6.8E-39 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TSH58p_18910 2fd36d6803e288ff03bd88d0703240b5 279 SUPERFAMILY SSF55315 11 108 6.83E-12 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like TSH58p_18910 2fd36d6803e288ff03bd88d0703240b5 279 Pfam PF00588 SpoU rRNA Methylase family 128 266 5.8E-27 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TSH58p_18910 2fd36d6803e288ff03bd88d0703240b5 279 SUPERFAMILY SSF75217 121 269 4.58E-33 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases TSH58p_25085 a22f5c1657381872cd9472941740c7ec 414 Pfam PF00534 Glycosyl transferases group 1 195 359 8.5E-13 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 TSH58p_25085 a22f5c1657381872cd9472941740c7ec 414 SUPERFAMILY SSF53756 106 409 2.62E-33 T 14-10-2018 TSH58p_25085 a22f5c1657381872cd9472941740c7ec 414 Gene3D G3DSA:3.40.50.2000 192 413 4.5E-32 T 14-10-2018 TSH58p_08775 7d7ee5a1067dcfb5a4de58843a89c55e 367 SUPERFAMILY SSF51395 2 363 2.75E-130 T 14-10-2018 TSH58p_08775 7d7ee5a1067dcfb5a4de58843a89c55e 367 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 341 1.4E-90 T 14-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 TSH58p_08775 7d7ee5a1067dcfb5a4de58843a89c55e 367 Gene3D G3DSA:3.20.20.70 3 367 4.2E-147 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_02275 29627d97a895be8fed1a73307429a950 569 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 2 563 36.319 T 14-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 TSH58p_02275 29627d97a895be8fed1a73307429a950 569 PIRSF PIRSF001294 1 565 2.7E-242 T 14-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 TSH58p_02275 29627d97a895be8fed1a73307429a950 569 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 1 562 6.9E-238 T 14-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 TSH58p_02275 29627d97a895be8fed1a73307429a950 569 Pfam PF03814 Potassium-transporting ATPase A subunit 11 561 5.5E-247 T 14-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 TSH58p_28380 9f69db7cee3074c0be9fb40ebda311bb 238 Gene3D G3DSA:3.40.50.300 20 139 4.3E-16 T 14-10-2018 TSH58p_28380 9f69db7cee3074c0be9fb40ebda311bb 238 Pfam PF00308 Bacterial dnaA protein 72 177 3.4E-6 T 14-10-2018 IPR013317 Chromosomal replication initiator protein DnaA TSH58p_28380 9f69db7cee3074c0be9fb40ebda311bb 238 SUPERFAMILY SSF52540 4 177 5.78E-11 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_28380 9f69db7cee3074c0be9fb40ebda311bb 238 Gene3D G3DSA:1.10.8.60 142 208 1.0E-10 T 14-10-2018 TSH58p_24145 db61ec7cdeccdf5c2aeff335cd51c736 1138 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 1059 1136 2.9E-19 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain TSH58p_24145 db61ec7cdeccdf5c2aeff335cd51c736 1138 SUPERFAMILY SSF117143 80 332 5.62E-25 T 14-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like TSH58p_24145 db61ec7cdeccdf5c2aeff335cd51c736 1138 Pfam PF00460 Flagella basal body rod protein 8 37 3.0E-7 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 TSH58p_24145 db61ec7cdeccdf5c2aeff335cd51c736 1138 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 6 377 2.0E-39 T 14-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G TSH58p_24145 db61ec7cdeccdf5c2aeff335cd51c736 1138 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 779 1119 2.1E-31 T 14-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G TSH58p_24145 db61ec7cdeccdf5c2aeff335cd51c736 1138 SUPERFAMILY SSF117143 924 1098 1.7E-14 T 14-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like TSH58p_17825 e22358bdce2434f422e67e03d5855785 1533 Gene3D G3DSA:3.90.550.10 964 1243 2.0E-32 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_17825 e22358bdce2434f422e67e03d5855785 1533 Gene3D G3DSA:3.90.550.10 427 696 2.0E-60 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_17825 e22358bdce2434f422e67e03d5855785 1533 Pfam PF00535 Glycosyl transferase family 2 709 893 4.8E-15 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_17825 e22358bdce2434f422e67e03d5855785 1533 Pfam PF00535 Glycosyl transferase family 2 452 582 6.6E-28 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_17825 e22358bdce2434f422e67e03d5855785 1533 Pfam PF00535 Glycosyl transferase family 2 1007 1163 4.6E-17 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_17825 e22358bdce2434f422e67e03d5855785 1533 SUPERFAMILY SSF53448 449 653 6.03E-48 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_17825 e22358bdce2434f422e67e03d5855785 1533 Gene3D G3DSA:3.90.550.10 697 938 3.5E-36 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_17825 e22358bdce2434f422e67e03d5855785 1533 SUPERFAMILY SSF53448 996 1212 1.36E-35 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_17825 e22358bdce2434f422e67e03d5855785 1533 SUPERFAMILY SSF53448 705 937 2.92E-37 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_05320 97d9386be752f745fcc28460b3869a7e 429 SUPERFAMILY SSF53383 8 426 8.55E-118 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_05320 97d9386be752f745fcc28460b3869a7e 429 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 10 426 1.8E-128 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TSH58p_05320 97d9386be752f745fcc28460b3869a7e 429 Gene3D G3DSA:3.90.1150.10 295 429 7.9E-49 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_05320 97d9386be752f745fcc28460b3869a7e 429 PIRSF PIRSF001434 1 429 9.2E-118 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TSH58p_05320 97d9386be752f745fcc28460b3869a7e 429 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 9 426 2.3E-179 T 14-10-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 TSH58p_05320 97d9386be752f745fcc28460b3869a7e 429 Gene3D G3DSA:3.40.640.10 8 291 2.8E-94 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_03890 4fc775dc47444a378681157e96e1d3dc 320 Pfam PF03186 CobD/Cbib protein 8 302 4.4E-90 T 14-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 TSH58p_03890 4fc775dc47444a378681157e96e1d3dc 320 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 320 99.362 T 14-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 TSH58p_03890 4fc775dc47444a378681157e96e1d3dc 320 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 4 299 6.2E-60 T 14-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 TSH58p_01765 93232a4deaba04242607745275e57259 588 SUPERFAMILY SSF161098 21 284 3.79E-46 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_01765 93232a4deaba04242607745275e57259 588 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 413 582 3.7E-11 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_01765 93232a4deaba04242607745275e57259 588 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 134 280 7.2E-9 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_01765 93232a4deaba04242607745275e57259 588 Gene3D G3DSA:1.10.3720.10 23 290 2.1E-50 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_01765 93232a4deaba04242607745275e57259 588 Gene3D G3DSA:1.10.3720.10 332 587 4.2E-45 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_01765 93232a4deaba04242607745275e57259 588 SUPERFAMILY SSF161098 335 585 2.62E-48 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_09840 50b80d66ebc4858aced96d0cb98f2750 565 Pfam PF00672 HAMP domain 217 263 1.5E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_09840 50b80d66ebc4858aced96d0cb98f2750 565 SUPERFAMILY SSF58104 244 558 1.44E-55 T 14-10-2018 TSH58p_09840 50b80d66ebc4858aced96d0cb98f2750 565 Gene3D G3DSA:1.10.287.950 278 563 2.3E-50 T 14-10-2018 TSH58p_09840 50b80d66ebc4858aced96d0cb98f2750 565 SMART SM00304 215 268 4.7E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_09840 50b80d66ebc4858aced96d0cb98f2750 565 SMART SM00283 305 559 8.7E-43 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_09840 50b80d66ebc4858aced96d0cb98f2750 565 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 387 492 3.1E-28 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_09840 50b80d66ebc4858aced96d0cb98f2750 565 Gene3D G3DSA:1.20.1480.50 175 277 1.9E-19 T 14-10-2018 TSH58p_09610 06e3fd3703b31633c532398ce5d7c593 306 PRINTS PR00996 Glutamate methyltransferase family signature 246 260 4.1E-47 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_09610 06e3fd3703b31633c532398ce5d7c593 306 PRINTS PR00996 Glutamate methyltransferase family signature 96 108 4.1E-47 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_09610 06e3fd3703b31633c532398ce5d7c593 306 PRINTS PR00996 Glutamate methyltransferase family signature 139 159 4.1E-47 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_09610 06e3fd3703b31633c532398ce5d7c593 306 PRINTS PR00996 Glutamate methyltransferase family signature 265 288 4.1E-47 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_09610 06e3fd3703b31633c532398ce5d7c593 306 PRINTS PR00996 Glutamate methyltransferase family signature 57 70 4.1E-47 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_09610 06e3fd3703b31633c532398ce5d7c593 306 PRINTS PR00996 Glutamate methyltransferase family signature 175 191 4.1E-47 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_09610 06e3fd3703b31633c532398ce5d7c593 306 Pfam PF03705 CheR methyltransferase, all-alpha domain 37 87 1.3E-14 T 14-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal TSH58p_09610 06e3fd3703b31633c532398ce5d7c593 306 SMART SM00138 35 306 1.1E-109 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TSH58p_09610 06e3fd3703b31633c532398ce5d7c593 306 SUPERFAMILY SSF53335 103 304 3.41E-57 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_09610 06e3fd3703b31633c532398ce5d7c593 306 Gene3D G3DSA:3.40.50.150 102 306 1.3E-64 T 14-10-2018 TSH58p_09610 06e3fd3703b31633c532398ce5d7c593 306 PIRSF PIRSF000410 20 306 1.1E-102 T 14-10-2018 IPR026024 Chemotaxis protein methyltransferase CheR TSH58p_09610 06e3fd3703b31633c532398ce5d7c593 306 Gene3D G3DSA:1.10.155.10 25 101 1.5E-23 T 14-10-2018 IPR036804 Chemotaxis receptor methyltransferase CheR, N-terminal domain superfamily TSH58p_09610 06e3fd3703b31633c532398ce5d7c593 306 Pfam PF01739 CheR methyltransferase, SAM binding domain 103 300 4.7E-63 T 14-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal TSH58p_09610 06e3fd3703b31633c532398ce5d7c593 306 SUPERFAMILY SSF47757 27 102 1.57E-17 T 14-10-2018 TSH58p_05730 c97abdfc7a09823283f2ef4de4ea8cf8 788 Gene3D G3DSA:3.10.20.310 208 298 6.3E-23 T 14-10-2018 TSH58p_05730 c97abdfc7a09823283f2ef4de4ea8cf8 788 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 54 788 24.701 T 14-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 TSH58p_05730 c97abdfc7a09823283f2ef4de4ea8cf8 788 Gene3D G3DSA:3.10.20.310 371 455 6.2E-25 T 14-10-2018 TSH58p_05730 c97abdfc7a09823283f2ef4de4ea8cf8 788 Gene3D G3DSA:3.10.20.310 299 370 1.0E-15 T 14-10-2018 TSH58p_05730 c97abdfc7a09823283f2ef4de4ea8cf8 788 Gene3D G3DSA:3.10.20.310 127 205 4.7E-17 T 14-10-2018 TSH58p_05730 c97abdfc7a09823283f2ef4de4ea8cf8 788 PIRSF PIRSF006076 4 788 5.4E-259 T 14-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 TSH58p_05730 c97abdfc7a09823283f2ef4de4ea8cf8 788 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 60 788 3.0E-247 T 14-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 TSH58p_05730 c97abdfc7a09823283f2ef4de4ea8cf8 788 Gene3D G3DSA:3.10.20.310 54 126 2.2E-19 T 14-10-2018 TSH58p_05730 c97abdfc7a09823283f2ef4de4ea8cf8 788 Pfam PF01103 Surface antigen 480 788 1.7E-80 T 14-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 TSH58p_05730 c97abdfc7a09823283f2ef4de4ea8cf8 788 Pfam PF07244 Surface antigen variable number repeat 209 295 2.5E-14 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 TSH58p_05730 c97abdfc7a09823283f2ef4de4ea8cf8 788 Pfam PF07244 Surface antigen variable number repeat 382 450 3.5E-11 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 TSH58p_05730 c97abdfc7a09823283f2ef4de4ea8cf8 788 Pfam PF07244 Surface antigen variable number repeat 128 204 1.8E-15 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 TSH58p_05730 c97abdfc7a09823283f2ef4de4ea8cf8 788 Pfam PF07244 Surface antigen variable number repeat 298 377 3.0E-12 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 TSH58p_05730 c97abdfc7a09823283f2ef4de4ea8cf8 788 Pfam PF07244 Surface antigen variable number repeat 60 125 5.3E-8 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 TSH58p_05730 c97abdfc7a09823283f2ef4de4ea8cf8 788 Gene3D G3DSA:2.40.160.50 456 788 1.0E-102 T 14-10-2018 TSH58p_23805 d63b5c7d2e890089a4bdcec07e5d18a0 148 Pfam PF02627 Carboxymuconolactone decarboxylase family 11 94 4.7E-12 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TSH58p_23805 d63b5c7d2e890089a4bdcec07e5d18a0 148 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 33 62 1.0E-9 T 14-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TSH58p_23805 d63b5c7d2e890089a4bdcec07e5d18a0 148 SUPERFAMILY SSF69118 4 144 1.96E-35 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TSH58p_23805 d63b5c7d2e890089a4bdcec07e5d18a0 148 Gene3D G3DSA:1.20.1290.10 1 147 6.4E-37 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TSH58p_14705 30b1e448c87d1331176e846aea09d5f6 332 Pfam PF13439 Glycosyltransferase Family 4 14 165 3.0E-16 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TSH58p_14705 30b1e448c87d1331176e846aea09d5f6 332 Pfam PF13692 Glycosyl transferases group 1 179 292 6.0E-19 T 14-10-2018 TSH58p_14705 30b1e448c87d1331176e846aea09d5f6 332 SUPERFAMILY SSF53756 2 328 2.59E-66 T 14-10-2018 TSH58p_14705 30b1e448c87d1331176e846aea09d5f6 332 Gene3D G3DSA:3.40.50.2000 171 313 2.0E-26 T 14-10-2018 TSH58p_14705 30b1e448c87d1331176e846aea09d5f6 332 Gene3D G3DSA:3.40.50.2000 1 170 2.9E-23 T 14-10-2018 TSH58p_01050 ca1aab1f5a5c25574c797693ee68eabd 356 Pfam PF00144 Beta-lactamase 65 334 2.2E-24 T 14-10-2018 IPR001466 Beta-lactamase-related TSH58p_01050 ca1aab1f5a5c25574c797693ee68eabd 356 Gene3D G3DSA:3.40.710.10 32 338 3.4E-59 T 14-10-2018 TSH58p_01050 ca1aab1f5a5c25574c797693ee68eabd 356 SUPERFAMILY SSF56601 22 333 3.28E-63 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TSH58p_16145 e42dd1fbb0bd50d3a2af533f05a3c1a5 81 SMART SM00704 10 47 2.3E-12 T 14-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 TSH58p_16145 e42dd1fbb0bd50d3a2af533f05a3c1a5 81 SMART SM00704 50 79 0.12 T 14-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 TSH58p_16145 e42dd1fbb0bd50d3a2af533f05a3c1a5 81 Pfam PF09360 Iron-binding zinc finger CDGSH type 17 41 5.7E-10 T 14-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 TSH58p_16145 e42dd1fbb0bd50d3a2af533f05a3c1a5 81 Pfam PF09360 Iron-binding zinc finger CDGSH type 59 77 2.5E-6 T 14-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 TSH58p_16145 e42dd1fbb0bd50d3a2af533f05a3c1a5 81 Gene3D G3DSA:3.40.5.90 1 79 1.3E-32 T 14-10-2018 TSH58p_18900 740811ce4732b432f7c57a279ecfd961 489 SMART SM01060 5 390 5.5E-297 T 14-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TSH58p_18900 740811ce4732b432f7c57a279ecfd961 489 PRINTS PR00067 Catalase signature 81 99 1.4E-77 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TSH58p_18900 740811ce4732b432f7c57a279ecfd961 489 PRINTS PR00067 Catalase signature 102 119 1.4E-77 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TSH58p_18900 740811ce4732b432f7c57a279ecfd961 489 PRINTS PR00067 Catalase signature 286 313 1.4E-77 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TSH58p_18900 740811ce4732b432f7c57a279ecfd961 489 PRINTS PR00067 Catalase signature 318 344 1.4E-77 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TSH58p_18900 740811ce4732b432f7c57a279ecfd961 489 PRINTS PR00067 Catalase signature 121 139 1.4E-77 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TSH58p_18900 740811ce4732b432f7c57a279ecfd961 489 PRINTS PR00067 Catalase signature 18 41 1.4E-77 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TSH58p_18900 740811ce4732b432f7c57a279ecfd961 489 Gene3D G3DSA:2.40.180.10 1 481 2.7E-235 T 14-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 TSH58p_18900 740811ce4732b432f7c57a279ecfd961 489 PIRSF PIRSF038928 1 480 2.5E-226 T 14-10-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TSH58p_18900 740811ce4732b432f7c57a279ecfd961 489 Pfam PF06628 Catalase-related immune-responsive 414 474 7.4E-20 T 14-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TSH58p_18900 740811ce4732b432f7c57a279ecfd961 489 ProSitePatterns PS00438 Catalase proximal active site signature. 41 57 - T 14-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TSH58p_18900 740811ce4732b432f7c57a279ecfd961 489 Pfam PF00199 Catalase 5 387 8.4E-199 T 14-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TSH58p_18900 740811ce4732b432f7c57a279ecfd961 489 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 331 339 - T 14-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TSH58p_18900 740811ce4732b432f7c57a279ecfd961 489 SUPERFAMILY SSF56634 3 480 2.62E-217 T 14-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TSH58p_01110 582d1e791ec0c5b091ff66f4d75f2148 144 Pfam PF02152 Dihydroneopterin aldolase 24 133 5.4E-20 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TSH58p_01110 582d1e791ec0c5b091ff66f4d75f2148 144 SUPERFAMILY SSF55620 21 136 1.33E-24 T 14-10-2018 TSH58p_01110 582d1e791ec0c5b091ff66f4d75f2148 144 SMART SM00905 24 134 4.5E-20 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TSH58p_01110 582d1e791ec0c5b091ff66f4d75f2148 144 TIGRFAM TIGR00526 folB_dom: FolB domain 34 137 5.2E-15 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TSH58p_01110 582d1e791ec0c5b091ff66f4d75f2148 144 Gene3D G3DSA:3.30.1130.10 7 140 7.9E-39 T 14-10-2018 TSH58p_01300 f208370d96fb958e927650b69bfaf23a 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 6.8E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_01300 f208370d96fb958e927650b69bfaf23a 200 SUPERFAMILY SSF46689 3 78 9.23E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_01300 f208370d96fb958e927650b69bfaf23a 200 SUPERFAMILY SSF48498 79 192 1.18E-23 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TSH58p_01300 f208370d96fb958e927650b69bfaf23a 200 Gene3D G3DSA:1.10.357.10 67 193 6.1E-27 T 14-10-2018 TSH58p_01300 f208370d96fb958e927650b69bfaf23a 200 Gene3D G3DSA:1.10.10.60 1 66 3.5E-21 T 14-10-2018 TSH58p_24960 bbf4cfb4a0cf0e1371cf0a1ff3150ef1 346 TIGRFAM TIGR00968 3a0106s01: sulfate ABC transporter, ATP-binding protein 3 242 5.6E-121 T 14-10-2018 IPR005666 Sulphate transport system permease protein 1 GO:0008272|GO:0015419|GO:0016020|GO:0043190 KEGG: 00920+3.6.3.25 TSH58p_24960 bbf4cfb4a0cf0e1371cf0a1ff3150ef1 346 Gene3D G3DSA:3.40.50.300 1 256 3.4E-78 T 14-10-2018 TSH58p_24960 bbf4cfb4a0cf0e1371cf0a1ff3150ef1 346 SUPERFAMILY SSF52540 3 244 3.19E-87 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_24960 bbf4cfb4a0cf0e1371cf0a1ff3150ef1 346 Pfam PF12857 TOBE-like domain 289 332 2.0E-7 T 14-10-2018 IPR024765 TOBE-like domain KEGG: 00920+3.6.3.25 TSH58p_24960 bbf4cfb4a0cf0e1371cf0a1ff3150ef1 346 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_24960 bbf4cfb4a0cf0e1371cf0a1ff3150ef1 346 Pfam PF00005 ABC transporter 18 164 7.1E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_24960 bbf4cfb4a0cf0e1371cf0a1ff3150ef1 346 SUPERFAMILY SSF50331 240 342 7.44E-13 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSH58p_24960 bbf4cfb4a0cf0e1371cf0a1ff3150ef1 346 SMART SM00382 27 214 2.8E-20 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_06470 8df48699402b4475e6710f57f598dad4 222 Pfam PF09335 SNARE associated Golgi protein 34 164 3.0E-17 T 14-10-2018 IPR032816 SNARE associated Golgi protein TSH58p_10095 d73ba3c917ad227a37556265484928cb 262 Gene3D G3DSA:3.40.50.300 3 256 2.0E-63 T 14-10-2018 TSH58p_10095 d73ba3c917ad227a37556265484928cb 262 SMART SM00382 34 215 7.5E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_10095 d73ba3c917ad227a37556265484928cb 262 Pfam PF00005 ABC transporter 28 164 2.3E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_10095 d73ba3c917ad227a37556265484928cb 262 SUPERFAMILY SSF52540 4 235 1.58E-70 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_27315 d2e285002140457f567b065a79d7b4a1 362 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 38 320 7.3E-65 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 TSH58p_27315 d2e285002140457f567b065a79d7b4a1 362 SUPERFAMILY SSF53850 134 280 2.14E-5 T 14-10-2018 TSH58p_27315 d2e285002140457f567b065a79d7b4a1 362 Gene3D G3DSA:3.40.190.170 32 336 5.9E-131 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily TSH58p_27315 d2e285002140457f567b065a79d7b4a1 362 PIRSF PIRSF039026 1 355 1.7E-125 T 14-10-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like TSH58p_27315 d2e285002140457f567b065a79d7b4a1 362 Gene3D G3DSA:3.40.190.10 152 322 5.9E-131 T 14-10-2018 TSH58p_16335 21dad59914745099f81ebd7712aed7de 660 SUPERFAMILY SSF51735 293 568 1.56E-55 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_16335 21dad59914745099f81ebd7712aed7de 660 Pfam PF02719 Polysaccharide biosynthesis protein 296 590 2.5E-111 T 14-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain TSH58p_16335 21dad59914745099f81ebd7712aed7de 660 Gene3D G3DSA:3.40.50.720 292 620 2.0E-109 T 14-10-2018 TSH58p_16335 21dad59914745099f81ebd7712aed7de 660 SUPERFAMILY SSF53335 105 336 5.48E-5 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_16335 21dad59914745099f81ebd7712aed7de 660 Gene3D G3DSA:3.40.50.720 145 277 4.6E-20 T 14-10-2018 TSH58p_16335 21dad59914745099f81ebd7712aed7de 660 Pfam PF13727 CoA-binding domain 61 206 3.9E-10 T 14-10-2018 TSH58p_24270 763c6acf6272fdd9eb3cb847afe529f9 198 Pfam PF13628 Domain of unknown function (DUF4142) 36 168 4.8E-28 T 14-10-2018 IPR025419 Domain of unknown function DUF4142 TSH58p_11050 57915c0eaf405ae5dbb88128737a3276 225 Gene3D G3DSA:3.30.420.10 2 172 2.0E-53 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TSH58p_11050 57915c0eaf405ae5dbb88128737a3276 225 Pfam PF00929 Exonuclease 4 163 5.5E-37 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TSH58p_11050 57915c0eaf405ae5dbb88128737a3276 225 SUPERFAMILY SSF53098 1 169 3.8E-55 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily TSH58p_11050 57915c0eaf405ae5dbb88128737a3276 225 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 3 168 2.8E-50 T 14-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSH58p_11050 57915c0eaf405ae5dbb88128737a3276 225 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 2 222 4.4E-83 T 14-10-2018 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSH58p_11050 57915c0eaf405ae5dbb88128737a3276 225 SMART SM00479 2 172 8.9E-49 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TSH58p_20870 4c9ab3469bbf488ecc349eceddfd5063 179 SUPERFAMILY SSF48403 30 174 6.02E-33 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily TSH58p_20870 4c9ab3469bbf488ecc349eceddfd5063 179 Pfam PF12796 Ankyrin repeats (3 copies) 59 151 1.7E-15 T 14-10-2018 IPR020683 Ankyrin repeat-containing domain TSH58p_20870 4c9ab3469bbf488ecc349eceddfd5063 179 SMART SM00248 87 116 0.15 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 TSH58p_20870 4c9ab3469bbf488ecc349eceddfd5063 179 SMART SM00248 120 149 0.014 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 TSH58p_20870 4c9ab3469bbf488ecc349eceddfd5063 179 SMART SM00248 54 83 9.8E-4 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 TSH58p_20870 4c9ab3469bbf488ecc349eceddfd5063 179 Gene3D G3DSA:1.25.40.20 15 179 3.8E-38 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily TSH58p_17125 3fb66dcca9e98353a1e9e5e936977b6d 869 Gene3D G3DSA:3.90.550.10 411 632 5.4E-63 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_17125 3fb66dcca9e98353a1e9e5e936977b6d 869 Pfam PF13641 Glycosyltransferase like family 2 419 648 1.6E-31 T 14-10-2018 TSH58p_17125 3fb66dcca9e98353a1e9e5e936977b6d 869 SUPERFAMILY SSF51445 38 297 2.05E-46 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_17125 3fb66dcca9e98353a1e9e5e936977b6d 869 SUPERFAMILY SSF53448 412 675 7.03E-54 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_17125 3fb66dcca9e98353a1e9e5e936977b6d 869 Gene3D G3DSA:3.20.20.80 35 300 6.4E-16 T 14-10-2018 TSH58p_13885 a159b2c43e0f9c71e3bc4acdbec5c585 274 SUPERFAMILY SSF81296 181 266 1.96E-13 T 14-10-2018 IPR014756 Immunoglobulin E-set TSH58p_13885 a159b2c43e0f9c71e3bc4acdbec5c585 274 Pfam PF08770 Sulphur oxidation protein SoxZ 180 262 1.2E-10 T 14-10-2018 IPR014880 Sulphur oxidation protein SoxZ TSH58p_13885 a159b2c43e0f9c71e3bc4acdbec5c585 274 Pfam PF13501 Sulfur oxidation protein SoxY 40 143 1.5E-26 T 14-10-2018 IPR032711 Ig-like SoxY domain TSH58p_13885 a159b2c43e0f9c71e3bc4acdbec5c585 274 TIGRFAM TIGR04557 fuse_rel_SoxYZ: quinoprotein dehydrogenase-associated SoxYZ-like carrier 34 259 6.7E-64 T 14-10-2018 IPR030831 Quinoprotein dehydrogenase-associated SoxYZ-like carrier TSH58p_13885 a159b2c43e0f9c71e3bc4acdbec5c585 274 Gene3D G3DSA:2.60.40.2470 28 143 3.4E-24 T 14-10-2018 IPR038162 Ig-like SoxY domain superfamily TSH58p_13885 a159b2c43e0f9c71e3bc4acdbec5c585 274 Gene3D G3DSA:2.60.40.10 175 266 5.5E-9 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_11415 913e13a5fc4b4767e280bf4c8f6b35cb 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 12 88 6.0E-29 T 14-10-2018 TSH58p_11415 913e13a5fc4b4767e280bf4c8f6b35cb 89 Gene3D G3DSA:1.10.287.10 1 89 2.0E-36 T 14-10-2018 TSH58p_11415 913e13a5fc4b4767e280bf4c8f6b35cb 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_11415 913e13a5fc4b4767e280bf4c8f6b35cb 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 6 89 4.0E-39 T 14-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_11415 913e13a5fc4b4767e280bf4c8f6b35cb 89 SMART SM01387 8 88 7.5E-52 T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_11415 913e13a5fc4b4767e280bf4c8f6b35cb 89 Pfam PF00312 Ribosomal protein S15 8 88 3.8E-38 T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_11415 913e13a5fc4b4767e280bf4c8f6b35cb 89 SUPERFAMILY SSF47060 3 89 2.18E-36 T 14-10-2018 IPR009068 S15/NS1, RNA-binding TSH58p_11415 913e13a5fc4b4767e280bf4c8f6b35cb 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 23.208 T 14-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_20430 f017ed83ef685a4bd96f914f4041447f 153 ProDom PD037294 PEPTIDE ACMNPV ORF38 ORF ORF_59 ORF61 ORF7 PXORF52 ORF-30 ORF79 41 73 2.0E-4 T 14-10-2018 TSH58p_20430 f017ed83ef685a4bd96f914f4041447f 153 Pfam PF00293 NUDIX domain 20 139 3.7E-16 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TSH58p_20430 f017ed83ef685a4bd96f914f4041447f 153 PRINTS PR00502 NUDIX hydrolase family signature 46 60 2.3E-5 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TSH58p_20430 f017ed83ef685a4bd96f914f4041447f 153 PRINTS PR00502 NUDIX hydrolase family signature 60 75 2.3E-5 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TSH58p_20430 f017ed83ef685a4bd96f914f4041447f 153 Gene3D G3DSA:3.90.79.10 9 150 1.1E-31 T 14-10-2018 TSH58p_20430 f017ed83ef685a4bd96f914f4041447f 153 SUPERFAMILY SSF55811 8 146 1.49E-32 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TSH58p_20430 f017ed83ef685a4bd96f914f4041447f 153 ProSitePatterns PS00893 Nudix box signature. 51 72 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TSH58p_00395 3570701a625419b7748f67c94d8062ba 379 PIRSF PIRSF016578 3 190 1.6E-9 T 14-10-2018 TSH58p_00395 3570701a625419b7748f67c94d8062ba 379 PIRSF PIRSF016578 221 378 3.6E-16 T 14-10-2018 TSH58p_00395 3570701a625419b7748f67c94d8062ba 379 Gene3D G3DSA:2.40.110.10 120 232 2.3E-45 T 14-10-2018 TSH58p_00395 3570701a625419b7748f67c94d8062ba 379 Gene3D G3DSA:1.10.540.10 1 119 7.0E-43 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TSH58p_00395 3570701a625419b7748f67c94d8062ba 379 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 335 354 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TSH58p_00395 3570701a625419b7748f67c94d8062ba 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 9.9E-35 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TSH58p_00395 3570701a625419b7748f67c94d8062ba 379 Gene3D G3DSA:1.20.140.10 233 378 6.7E-58 T 14-10-2018 TSH58p_00395 3570701a625419b7748f67c94d8062ba 379 SUPERFAMILY SSF47203 225 378 4.83E-62 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TSH58p_00395 3570701a625419b7748f67c94d8062ba 379 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TSH58p_00395 3570701a625419b7748f67c94d8062ba 379 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 215 4.2E-27 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TSH58p_00395 3570701a625419b7748f67c94d8062ba 379 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 376 3.3E-51 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TSH58p_00395 3570701a625419b7748f67c94d8062ba 379 SUPERFAMILY SSF56645 1 240 1.1E-87 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TSH58p_18375 2e9c23594e283ca3d89d6549529bc9fd 302 SUPERFAMILY SSF51735 1 292 2.17E-94 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_18375 2e9c23594e283ca3d89d6549529bc9fd 302 Pfam PF04321 RmlD substrate binding domain 3 291 1.0E-105 T 14-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 TSH58p_18375 2e9c23594e283ca3d89d6549529bc9fd 302 Gene3D G3DSA:3.40.50.720 4 278 2.3E-102 T 14-10-2018 TSH58p_18375 2e9c23594e283ca3d89d6549529bc9fd 302 Gene3D G3DSA:3.90.25.10 161 285 2.3E-102 T 14-10-2018 TSH58p_18375 2e9c23594e283ca3d89d6549529bc9fd 302 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 3 290 2.7E-94 T 14-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 TSH58p_28240 e014f09a8f8528b5bc788585360cfb07 370 Pfam PF10098 Uncharacterised protein conserved in bacteria (DUF2336) 90 349 3.0E-76 T 14-10-2018 IPR019285 Protein of unknown function DUF2336 TSH58p_28240 e014f09a8f8528b5bc788585360cfb07 370 PIRSF PIRSF035865 1 366 5.9E-83 T 14-10-2018 IPR014598 Uncharacterised conserved protein UCP035865 TSH58p_17010 6d24c5f3fec8406c65c6ccfd656dbcf8 100 Pfam PF03937 Flavinator of succinate dehydrogenase 18 89 3.0E-27 T 14-10-2018 IPR005631 Flavinator of succinate dehydrogenase TSH58p_17010 6d24c5f3fec8406c65c6ccfd656dbcf8 100 SUPERFAMILY SSF109910 12 91 3.14E-26 T 14-10-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily TSH58p_17010 6d24c5f3fec8406c65c6ccfd656dbcf8 100 Gene3D G3DSA:1.10.150.250 13 98 8.2E-27 T 14-10-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily TSH58p_21760 91f2ab3dc51fd685c5cf929164a09759 287 Hamap MF_01830 Putative hydro-lyase . 17 271 50.865 T 14-10-2018 IPR016938 Uncharacterised protein family UPF0317 TSH58p_21760 91f2ab3dc51fd685c5cf929164a09759 287 Gene3D G3DSA:3.40.1640.10 30 259 8.0E-92 T 14-10-2018 TSH58p_21760 91f2ab3dc51fd685c5cf929164a09759 287 SUPERFAMILY SSF160920 20 263 4.18E-107 T 14-10-2018 IPR038021 Putative hydro-lyase TSH58p_21760 91f2ab3dc51fd685c5cf929164a09759 287 Gene3D G3DSA:3.30.2040.10 131 243 8.0E-92 T 14-10-2018 TSH58p_21760 91f2ab3dc51fd685c5cf929164a09759 287 PIRSF PIRSF029755 7 272 1.4E-111 T 14-10-2018 IPR016938 Uncharacterised protein family UPF0317 TSH58p_21760 91f2ab3dc51fd685c5cf929164a09759 287 Pfam PF07286 Protein of unknown function (DUF1445) 121 263 4.6E-64 T 14-10-2018 IPR009906 D-glutamate cyclase TSH58p_28055 ce9a07645e722b2bf41dd15f4a5f353c 200 Pfam PF04955 HupE / UreJ protein 14 196 1.4E-57 T 14-10-2018 IPR007038 Hydrogenase/Urease accessory protein HupE/UreJ protein TSH58p_28055 ce9a07645e722b2bf41dd15f4a5f353c 200 PIRSF PIRSF016919 2 200 2.9E-59 T 14-10-2018 IPR007038 Hydrogenase/Urease accessory protein HupE/UreJ protein TSH58p_09000 a52218aff271c2907108ccdd4864328a 214 Gene3D G3DSA:2.60.120.620 18 189 1.9E-15 T 14-10-2018 TSH58p_09000 a52218aff271c2907108ccdd4864328a 214 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 109 184 1.0E-8 T 14-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 TSH58p_07875 b7c3c8f4b735220d2f92b6f049b799f6 131 Pfam PF03776 Septum formation topological specificity factor MinE 14 81 2.1E-24 T 14-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 TSH58p_07875 b7c3c8f4b735220d2f92b6f049b799f6 131 Hamap MF_00262 Cell division topological specificity factor [minE]. 3 84 18.0 T 14-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 TSH58p_07875 b7c3c8f4b735220d2f92b6f049b799f6 131 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 1 81 2.8E-27 T 14-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 TSH58p_07875 b7c3c8f4b735220d2f92b6f049b799f6 131 Gene3D G3DSA:3.30.1070.10 20 79 2.3E-25 T 14-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 TSH58p_07875 b7c3c8f4b735220d2f92b6f049b799f6 131 SUPERFAMILY SSF55229 33 84 7.19E-16 T 14-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 TSH58p_08880 edc3da00a964d31273a9d3ffd2533378 127 PIRSF PIRSF009151 1 121 4.7E-56 T 14-10-2018 IPR008497 Protein of unknown function DUF779 TSH58p_08880 edc3da00a964d31273a9d3ffd2533378 127 Pfam PF05610 Protein of unknown function (DUF779) 14 107 2.3E-46 T 14-10-2018 IPR008497 Protein of unknown function DUF779 TSH58p_23575 1eee9dd060b74b86ddd5ba617a78023a 242 SUPERFAMILY SSF53681 129 240 1.96E-23 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TSH58p_23575 1eee9dd060b74b86ddd5ba617a78023a 242 Pfam PF01177 Asp/Glu/Hydantoin racemase 17 235 1.2E-43 T 14-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TSH58p_23575 1eee9dd060b74b86ddd5ba617a78023a 242 SUPERFAMILY SSF53681 12 126 6.1E-24 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TSH58p_23575 1eee9dd060b74b86ddd5ba617a78023a 242 Gene3D G3DSA:3.40.50.1860 12 232 5.7E-65 T 14-10-2018 TSH58p_23575 1eee9dd060b74b86ddd5ba617a78023a 242 TIGRFAM TIGR00035 asp_race: aspartate racemase 12 241 4.4E-52 T 14-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 TSH58p_23575 1eee9dd060b74b86ddd5ba617a78023a 242 Gene3D G3DSA:3.40.50.1860 114 226 5.7E-65 T 14-10-2018 TSH58p_26600 e9f1cdbda4c558c9015e02caa968aec2 171 Pfam PF05128 Domain of unknown function (DUF697) 4 111 5.2E-12 T 14-10-2018 IPR021147 Protein of unknown function DUF697 TSH58p_15665 e68e7e4f983d7013e04bca6e8b7126ca 196 Pfam PF00583 Acetyltransferase (GNAT) family 65 169 1.3E-14 T 14-10-2018 IPR000182 GNAT domain TSH58p_15665 e68e7e4f983d7013e04bca6e8b7126ca 196 SUPERFAMILY SSF55729 4 178 2.16E-29 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_15665 e68e7e4f983d7013e04bca6e8b7126ca 196 Gene3D G3DSA:3.40.630.30 6 185 1.7E-34 T 14-10-2018 TSH58p_24390 0afb03463aeab38da0f1a2e54037dbb6 124 Pfam PF09912 Uncharacterized protein conserved in bacteria (DUF2141) 7 110 1.7E-29 T 14-10-2018 IPR018673 Protein of unknown function DUF2141 TSH58p_06230 1389754b830ae6788b4ce287f829653c 122 SUPERFAMILY SSF46946 2 121 6.39E-47 T 14-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 TSH58p_06230 1389754b830ae6788b4ce287f829653c 122 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 27.526 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_06230 1389754b830ae6788b4ce287f829653c 122 Gene3D G3DSA:4.10.910.10 73 119 7.9E-27 T 14-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_06230 1389754b830ae6788b4ce287f829653c 122 PIRSF PIRSF002134 1 122 2.9E-45 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_06230 1389754b830ae6788b4ce287f829653c 122 Pfam PF00416 Ribosomal protein S13/S18 3 109 6.5E-33 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_06230 1389754b830ae6788b4ce287f829653c 122 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 14-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_06230 1389754b830ae6788b4ce287f829653c 122 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 1.8E-54 T 14-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_06230 1389754b830ae6788b4ce287f829653c 122 Gene3D G3DSA:1.10.8.50 1 72 1.5E-29 T 14-10-2018 TSH58p_07565 30cdc89ac48c4b59e4c5bd3945177320 257 Pfam PF01816 Leucine rich repeat variant 92 114 1.9E-5 T 14-10-2018 IPR004830 Leucine rich repeat variant TSH58p_07565 30cdc89ac48c4b59e4c5bd3945177320 257 Pfam PF05484 LRV protein FeS4 cluster 8 59 6.1E-26 T 14-10-2018 IPR008665 LRV FeS4 cluster TSH58p_07565 30cdc89ac48c4b59e4c5bd3945177320 257 Gene3D G3DSA:1.25.10.10 11 248 4.0E-74 T 14-10-2018 IPR011989 Armadillo-like helical TSH58p_07565 30cdc89ac48c4b59e4c5bd3945177320 257 SUPERFAMILY SSF48371 14 238 1.06E-43 T 14-10-2018 IPR016024 Armadillo-type fold TSH58p_28625 a0bfd3f040740fb00f02b61b56134705 225 SUPERFAMILY SSF161098 23 209 1.44E-34 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_28625 a0bfd3f040740fb00f02b61b56134705 225 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 49 218 6.0E-24 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_28625 a0bfd3f040740fb00f02b61b56134705 225 Gene3D G3DSA:1.10.3720.10 23 219 2.9E-29 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_15955 95fd3ec92eb4605d36fbd0bf37a70f59 349 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 161 175 - T 14-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSH58p_15955 95fd3ec92eb4605d36fbd0bf37a70f59 349 Pfam PF00849 RNA pseudouridylate synthase 114 270 3.9E-36 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSH58p_15955 95fd3ec92eb4605d36fbd0bf37a70f59 349 Gene3D G3DSA:3.10.290.10 27 96 1.4E-15 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TSH58p_15955 95fd3ec92eb4605d36fbd0bf37a70f59 349 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 37 344 1.8E-96 T 14-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSH58p_15955 95fd3ec92eb4605d36fbd0bf37a70f59 349 SMART SM00363 39 99 0.0033 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15955 95fd3ec92eb4605d36fbd0bf37a70f59 349 Pfam PF01479 S4 domain 39 85 1.8E-5 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15955 95fd3ec92eb4605d36fbd0bf37a70f59 349 Gene3D G3DSA:3.30.2350.10 97 336 4.2E-80 T 14-10-2018 TSH58p_15955 95fd3ec92eb4605d36fbd0bf37a70f59 349 SUPERFAMILY SSF55174 37 127 4.37E-8 T 14-10-2018 TSH58p_15955 95fd3ec92eb4605d36fbd0bf37a70f59 349 SUPERFAMILY SSF55120 100 346 1.52E-80 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSH58p_14585 92e017639ae5ffca47dc5eb1a1b56622 198 Pfam PF05951 Bacterial protein of unknown function (DUF882) 52 198 6.8E-58 T 14-10-2018 IPR010275 Protein of unknown function DUF882 TSH58p_14585 92e017639ae5ffca47dc5eb1a1b56622 198 Gene3D G3DSA:3.30.1380.10 101 198 2.5E-10 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSH58p_14585 92e017639ae5ffca47dc5eb1a1b56622 198 SUPERFAMILY SSF55166 82 198 1.88E-29 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSH58p_28450 a6fabbc8f0e47eb099082ff3e9c02d80 137 SMART SM00448 19 132 1.1E-35 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_28450 a6fabbc8f0e47eb099082ff3e9c02d80 137 Gene3D G3DSA:3.40.50.12740 18 137 7.0E-44 T 14-10-2018 TSH58p_28450 a6fabbc8f0e47eb099082ff3e9c02d80 137 SUPERFAMILY SSF52172 19 137 1.02E-36 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_28450 a6fabbc8f0e47eb099082ff3e9c02d80 137 Pfam PF00072 Response regulator receiver domain 21 133 4.0E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_08230 6dfb0a86bea505ae81f96028eb82d5be 352 Gene3D G3DSA:3.40.50.10330 64 179 6.8E-7 T 14-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 TSH58p_08230 6dfb0a86bea505ae81f96028eb82d5be 352 PIRSF PIRSF018567 1 350 4.7E-122 T 14-10-2018 IPR011391 Acetoin catabolism kinase AcoX TSH58p_08230 6dfb0a86bea505ae81f96028eb82d5be 352 SUPERFAMILY SSF111331 88 171 2.18E-7 T 14-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily TSH58p_08230 6dfb0a86bea505ae81f96028eb82d5be 352 Pfam PF01513 ATP-NAD kinase 5 285 1.2E-23 T 14-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 TSH58p_31740 0acb090875f0205c6896e12d12b14217 454 Gene3D G3DSA:3.30.565.10 307 445 7.0E-28 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_31740 0acb090875f0205c6896e12d12b14217 454 SUPERFAMILY SSF55874 312 444 2.74E-16 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_31740 0acb090875f0205c6896e12d12b14217 454 Pfam PF07730 Histidine kinase 229 304 1.6E-10 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TSH58p_31740 0acb090875f0205c6896e12d12b14217 454 SMART SM00387 348 447 1.1E-9 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_31740 0acb090875f0205c6896e12d12b14217 454 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 354 444 3.3E-6 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_20410 13f13fa2b8660a6e4d95d29beb8743a8 240 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 3 239 2.2E-107 T 14-10-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216|MetaCyc: PWY-7948 TSH58p_20410 13f13fa2b8660a6e4d95d29beb8743a8 240 Gene3D G3DSA:3.40.50.720 1 240 4.5E-78 T 14-10-2018 TSH58p_20410 13f13fa2b8660a6e4d95d29beb8743a8 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 2.4E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_20410 13f13fa2b8660a6e4d95d29beb8743a8 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 2.4E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_20410 13f13fa2b8660a6e4d95d29beb8743a8 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 2.4E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_20410 13f13fa2b8660a6e4d95d29beb8743a8 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 2.4E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_20410 13f13fa2b8660a6e4d95d29beb8743a8 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 2.4E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_20410 13f13fa2b8660a6e4d95d29beb8743a8 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 2.4E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_20410 13f13fa2b8660a6e4d95d29beb8743a8 240 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 178 2.6E-6 T 14-10-2018 TSH58p_20410 13f13fa2b8660a6e4d95d29beb8743a8 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 1.7E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_20410 13f13fa2b8660a6e4d95d29beb8743a8 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 1.7E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_20410 13f13fa2b8660a6e4d95d29beb8743a8 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 1.7E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_20410 13f13fa2b8660a6e4d95d29beb8743a8 240 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_20410 13f13fa2b8660a6e4d95d29beb8743a8 240 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 238 5.1E-61 T 14-10-2018 TSH58p_20410 13f13fa2b8660a6e4d95d29beb8743a8 240 SUPERFAMILY SSF51735 3 239 1.91E-77 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_29835 dcabfa0933fee3d03ac571e53ebc5963 526 SMART SM00490 256 337 5.6E-32 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_29835 dcabfa0933fee3d03ac571e53ebc5963 526 Pfam PF00271 Helicase conserved C-terminal domain 229 337 8.4E-29 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_29835 dcabfa0933fee3d03ac571e53ebc5963 526 SMART SM00487 20 220 2.0E-65 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSH58p_29835 dcabfa0933fee3d03ac571e53ebc5963 526 Gene3D G3DSA:3.40.50.300 1 208 4.1E-78 T 14-10-2018 TSH58p_29835 dcabfa0933fee3d03ac571e53ebc5963 526 Pfam PF00270 DEAD/DEAH box helicase 25 193 4.3E-52 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TSH58p_29835 dcabfa0933fee3d03ac571e53ebc5963 526 Gene3D G3DSA:3.40.50.300 211 369 3.3E-48 T 14-10-2018 TSH58p_29835 dcabfa0933fee3d03ac571e53ebc5963 526 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 151 159 - T 14-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site TSH58p_29835 dcabfa0933fee3d03ac571e53ebc5963 526 SUPERFAMILY SSF52540 73 350 5.03E-74 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_13015 189fd129b72268fda580331ccd34153c 332 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 146 0.0094 T 14-10-2018 TSH58p_13015 189fd129b72268fda580331ccd34153c 332 SUPERFAMILY SSF51735 2 318 2.04E-83 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_13015 189fd129b72268fda580331ccd34153c 332 Gene3D G3DSA:3.40.50.720 2 319 7.5E-80 T 14-10-2018 TSH58p_13015 189fd129b72268fda580331ccd34153c 332 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 250 9.2E-47 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TSH58p_13955 06b4e31619b0df909c18e4c669e57b0c 50 Pfam PF06945 Protein of unknown function (DUF1289) 5 30 2.2E-9 T 14-10-2018 IPR010710 Protein of unknown function DUF1289 TSH58p_18010 5527bb2796d6ac8f19e772302e5e4585 259 Gene3D G3DSA:3.30.300.20 91 229 1.1E-24 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta TSH58p_18010 5527bb2796d6ac8f19e772302e5e4585 259 Pfam PF02566 OsmC-like protein 131 237 2.1E-18 T 14-10-2018 IPR003718 OsmC/Ohr family TSH58p_18010 5527bb2796d6ac8f19e772302e5e4585 259 SUPERFAMILY SSF82784 106 237 1.31E-23 T 14-10-2018 IPR036102 OsmC/Ohr superfamily TSH58p_17135 8666f77e28d6c9121da2cf08dd36390f 58 Pfam PF05532 CsbD-like 4 52 9.4E-14 T 14-10-2018 IPR008462 CsbD-like domain TSH58p_17135 8666f77e28d6c9121da2cf08dd36390f 58 SUPERFAMILY SSF69047 1 53 6.15E-12 T 14-10-2018 IPR036629 YjbJ superfamily TSH58p_17135 8666f77e28d6c9121da2cf08dd36390f 58 Gene3D G3DSA:1.10.1470.10 1 56 1.7E-10 T 14-10-2018 IPR036629 YjbJ superfamily TSH58p_07545 9d3dd0e1201f641b09c4ab7f6d84f291 296 SUPERFAMILY SSF55073 3 165 1.18E-38 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_07545 9d3dd0e1201f641b09c4ab7f6d84f291 296 Gene3D G3DSA:3.30.70.1230 1 163 7.0E-40 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_07545 9d3dd0e1201f641b09c4ab7f6d84f291 296 Gene3D G3DSA:2.60.200.20 195 282 6.9E-14 T 14-10-2018 TSH58p_07545 9d3dd0e1201f641b09c4ab7f6d84f291 296 SUPERFAMILY SSF49879 192 253 3.06E-15 T 14-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 TSH58p_07545 9d3dd0e1201f641b09c4ab7f6d84f291 296 SMART SM00240 207 256 4.7E-6 T 14-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TSH58p_07545 9d3dd0e1201f641b09c4ab7f6d84f291 296 SMART SM00044 1 151 3.1E-4 T 14-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 TSH58p_07545 9d3dd0e1201f641b09c4ab7f6d84f291 296 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 5 152 1.2E-14 T 14-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 TSH58p_07545 9d3dd0e1201f641b09c4ab7f6d84f291 296 Pfam PF00498 FHA domain 208 255 1.3E-10 T 14-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TSH58p_20995 f1dd148a4702e12f586925e23e308d51 521 Gene3D G3DSA:3.10.105.10 281 493 8.9E-108 T 14-10-2018 TSH58p_20995 f1dd148a4702e12f586925e23e308d51 521 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 73 441 1.5E-70 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain TSH58p_20995 f1dd148a4702e12f586925e23e308d51 521 PIRSF PIRSF002741 21 518 3.4E-86 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TSH58p_20995 f1dd148a4702e12f586925e23e308d51 521 Gene3D G3DSA:3.90.76.10 62 180 8.9E-108 T 14-10-2018 TSH58p_20995 f1dd148a4702e12f586925e23e308d51 521 Gene3D G3DSA:3.40.190.10 40 505 8.9E-108 T 14-10-2018 TSH58p_20995 f1dd148a4702e12f586925e23e308d51 521 SUPERFAMILY SSF53850 26 516 9.41E-115 T 14-10-2018 TSH58p_30505 5e0550bae286f61cd2418a9749532e79 429 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 7 418 7.3E-87 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TSH58p_30505 5e0550bae286f61cd2418a9749532e79 429 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 423 1.5E-102 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSH58p_30505 5e0550bae286f61cd2418a9749532e79 429 PIRSF PIRSF006066 1 429 6.2E-117 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSH58p_05855 3d6f920f1c548a73283830211365eb72 508 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 7 489 7.0E-199 T 14-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05855 3d6f920f1c548a73283830211365eb72 508 Pfam PF00361 Proton-conducting membrane transporter 135 419 1.1E-88 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05855 3d6f920f1c548a73283830211365eb72 508 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 240 264 4.3E-49 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05855 3d6f920f1c548a73283830211365eb72 508 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 328 347 4.3E-49 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05855 3d6f920f1c548a73283830211365eb72 508 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 141 160 4.3E-49 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05855 3d6f920f1c548a73283830211365eb72 508 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 171 195 4.3E-49 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05855 3d6f920f1c548a73283830211365eb72 508 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 380 406 4.3E-49 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05855 3d6f920f1c548a73283830211365eb72 508 Pfam PF01059 NADH-ubiquinone oxidoreductase chain 4, amino terminus 78 130 2.9E-5 T 14-10-2018 IPR000260 NADH:ubiquinone oxidoreductase chain 4, N-terminal GO:0006120|GO:0055114 KEGG: 00190+1.6.5.3|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-5083|MetaCyc: PWY-6692|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_10570 66e27ea05ecb570b6aa87084a2dddd32 381 Gene3D G3DSA:2.10.230.10 152 216 1.1E-20 T 14-10-2018 TSH58p_10570 66e27ea05ecb570b6aa87084a2dddd32 381 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 355 7.8E-136 T 14-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 TSH58p_10570 66e27ea05ecb570b6aa87084a2dddd32 381 Gene3D G3DSA:2.60.260.20 260 366 1.7E-30 T 14-10-2018 TSH58p_10570 66e27ea05ecb570b6aa87084a2dddd32 381 SUPERFAMILY SSF57938 139 216 3.53E-21 T 14-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily TSH58p_10570 66e27ea05ecb570b6aa87084a2dddd32 381 Gene3D G3DSA:1.10.287.110 1 117 2.0E-38 T 14-10-2018 IPR036869 Chaperone J-domain superfamily TSH58p_10570 66e27ea05ecb570b6aa87084a2dddd32 381 SUPERFAMILY SSF49493 121 267 2.22E-20 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TSH58p_10570 66e27ea05ecb570b6aa87084a2dddd32 381 SMART SM00271 4 62 6.5E-32 T 14-10-2018 IPR001623 DnaJ domain TSH58p_10570 66e27ea05ecb570b6aa87084a2dddd32 381 Pfam PF00226 DnaJ domain 5 67 1.1E-28 T 14-10-2018 IPR001623 DnaJ domain TSH58p_10570 66e27ea05ecb570b6aa87084a2dddd32 381 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 375 41.793 T 14-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 TSH58p_10570 66e27ea05ecb570b6aa87084a2dddd32 381 SUPERFAMILY SSF49493 264 350 7.19E-24 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TSH58p_10570 66e27ea05ecb570b6aa87084a2dddd32 381 SUPERFAMILY SSF46565 1 109 4.71E-36 T 14-10-2018 IPR036869 Chaperone J-domain superfamily TSH58p_10570 66e27ea05ecb570b6aa87084a2dddd32 381 PRINTS PR00625 DnaJ domain signature 25 40 6.4E-32 T 14-10-2018 IPR001623 DnaJ domain TSH58p_10570 66e27ea05ecb570b6aa87084a2dddd32 381 PRINTS PR00625 DnaJ domain signature 42 62 6.4E-32 T 14-10-2018 IPR001623 DnaJ domain TSH58p_10570 66e27ea05ecb570b6aa87084a2dddd32 381 PRINTS PR00625 DnaJ domain signature 7 25 6.4E-32 T 14-10-2018 IPR001623 DnaJ domain TSH58p_10570 66e27ea05ecb570b6aa87084a2dddd32 381 PRINTS PR00625 DnaJ domain signature 62 81 6.4E-32 T 14-10-2018 IPR001623 DnaJ domain TSH58p_10570 66e27ea05ecb570b6aa87084a2dddd32 381 Pfam PF00684 DnaJ central domain 152 212 7.1E-14 T 14-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 TSH58p_10570 66e27ea05ecb570b6aa87084a2dddd32 381 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 14-10-2018 IPR018253 DnaJ domain, conserved site TSH58p_10570 66e27ea05ecb570b6aa87084a2dddd32 381 Pfam PF01556 DnaJ C terminal domain 126 339 4.4E-43 T 14-10-2018 IPR002939 Chaperone DnaJ, C-terminal TSH58p_09055 0d7c651f6048b8d01c4518931455fe1c 401 Gene3D G3DSA:3.40.640.10 63 286 1.5E-137 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_09055 0d7c651f6048b8d01c4518931455fe1c 401 Gene3D G3DSA:3.90.1150.10 26 392 1.5E-137 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_09055 0d7c651f6048b8d01c4518931455fe1c 401 SUPERFAMILY SSF53383 1 398 1.65E-115 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_09055 0d7c651f6048b8d01c4518931455fe1c 401 Pfam PF00155 Aminotransferase class I and II 32 392 1.9E-77 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSH58p_09055 0d7c651f6048b8d01c4518931455fe1c 401 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TSH58p_12110 61e419036c868bd640f3168a15530a99 278 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 29 272 7.8E-54 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_12110 61e419036c868bd640f3168a15530a99 278 SMART SM00062 28 274 5.0E-50 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_12110 61e419036c868bd640f3168a15530a99 278 SUPERFAMILY SSF53850 5 275 1.09E-60 T 14-10-2018 TSH58p_12110 61e419036c868bd640f3168a15530a99 278 Gene3D G3DSA:3.40.190.10 114 230 3.1E-79 T 14-10-2018 TSH58p_12110 61e419036c868bd640f3168a15530a99 278 Gene3D G3DSA:3.40.190.10 31 271 3.1E-79 T 14-10-2018 TSH58p_12110 61e419036c868bd640f3168a15530a99 278 SMART SM00079 28 273 4.3E-4 T 14-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 TSH58p_07720 11f73c4f8ce2e8b273fe4ae3b71e2bb7 401 PIRSF PIRSF005572 3 384 4.5E-131 T 14-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 TSH58p_07720 11f73c4f8ce2e8b273fe4ae3b71e2bb7 401 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 196 215 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site TSH58p_07720 11f73c4f8ce2e8b273fe4ae3b71e2bb7 401 SUPERFAMILY SSF53383 6 379 2.26E-104 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_07720 11f73c4f8ce2e8b273fe4ae3b71e2bb7 401 Pfam PF00266 Aminotransferase class-V 6 369 1.4E-91 T 14-10-2018 IPR000192 Aminotransferase class V domain TSH58p_07720 11f73c4f8ce2e8b273fe4ae3b71e2bb7 401 Gene3D G3DSA:1.10.260.50 17 282 1.3E-143 T 14-10-2018 TSH58p_07720 11f73c4f8ce2e8b273fe4ae3b71e2bb7 401 Gene3D G3DSA:3.90.1150.10 6 372 1.3E-143 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_07720 11f73c4f8ce2e8b273fe4ae3b71e2bb7 401 TIGRFAM TIGR03402 FeS_nifS: cysteine desulfurase NifS 6 386 5.2E-190 T 14-10-2018 IPR017772 Cysteine desulfurase NifS, bacterial/archaeal GO:0006520|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 TSH58p_07720 11f73c4f8ce2e8b273fe4ae3b71e2bb7 401 Gene3D G3DSA:3.40.640.10 64 238 1.3E-143 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_25505 12ef98396b681230a65324bf21348b9f 1256 Gene3D G3DSA:3.40.50.300 1 317 1.8E-35 T 14-10-2018 TSH58p_25505 12ef98396b681230a65324bf21348b9f 1256 Gene3D G3DSA:3.40.50.300 974 1235 4.8E-23 T 14-10-2018 TSH58p_25505 12ef98396b681230a65324bf21348b9f 1256 SUPERFAMILY SSF52540 1 1228 1.81E-34 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_25505 12ef98396b681230a65324bf21348b9f 1256 Pfam PF13476 AAA domain 9 223 1.9E-21 T 14-10-2018 IPR038729 Rad50/SbcC-type AAA domain TSH58p_25505 12ef98396b681230a65324bf21348b9f 1256 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1122 1194 2.8E-11 T 14-10-2018 TSH58p_10475 052b97809b760a2ab3908598b23809b9 183 Pfam PF10688 Bacterial inner membrane protein 16 171 2.8E-35 T 14-10-2018 IPR019629 Uncharacterised protein family HI1736/YgjV TSH58p_14115 a6afc13a1f05037579f2a05396d3d535 653 SUPERFAMILY SSF47226 542 650 5.89E-15 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_14115 a6afc13a1f05037579f2a05396d3d535 653 Pfam PF00072 Response regulator receiver domain 400 514 1.6E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_14115 a6afc13a1f05037579f2a05396d3d535 653 Gene3D G3DSA:1.20.120.160 535 652 2.0E-12 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_14115 a6afc13a1f05037579f2a05396d3d535 653 SUPERFAMILY SSF52172 396 520 2.7E-35 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_14115 a6afc13a1f05037579f2a05396d3d535 653 Gene3D G3DSA:3.40.50.2300 383 524 2.6E-36 T 14-10-2018 TSH58p_14115 a6afc13a1f05037579f2a05396d3d535 653 SMART SM00448 398 516 6.5E-35 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_14115 a6afc13a1f05037579f2a05396d3d535 653 Pfam PF01627 Hpt domain 565 648 3.9E-8 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TSH58p_26405 e3452b7ba2460424e9b825f35a05aeb6 315 SUPERFAMILY SSF54862 26 288 3.03E-72 T 14-10-2018 TSH58p_26405 e3452b7ba2460424e9b825f35a05aeb6 315 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 130 141 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_26405 e3452b7ba2460424e9b825f35a05aeb6 315 PIRSF PIRSF036298 1 312 5.8E-150 T 14-10-2018 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 TSH58p_26405 e3452b7ba2460424e9b825f35a05aeb6 315 TIGRFAM TIGR01582 FDH-beta: formate dehydrogenase, beta subunit 7 286 5.7E-140 T 14-10-2018 IPR006470 Formate dehydrogenase iron-sulphur subunit, Proteobacteria GO:0015944|GO:0016021|GO:0045333|GO:0051539 TSH58p_26405 e3452b7ba2460424e9b825f35a05aeb6 315 Pfam PF13247 4Fe-4S dicluster domain 89 185 9.3E-24 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_26405 e3452b7ba2460424e9b825f35a05aeb6 315 Gene3D G3DSA:3.30.70.20 25 224 1.6E-96 T 14-10-2018 TSH58p_26405 e3452b7ba2460424e9b825f35a05aeb6 315 Pfam PF09163 Formate dehydrogenase N, transmembrane 243 286 9.3E-21 T 14-10-2018 IPR015246 Formate dehydrogenase, transmembrane TSH58p_26405 e3452b7ba2460424e9b825f35a05aeb6 315 Gene3D G3DSA:3.30.70.20 19 159 1.6E-96 T 14-10-2018 TSH58p_26405 e3452b7ba2460424e9b825f35a05aeb6 315 Gene3D G3DSA:1.20.5.480 244 290 6.3E-15 T 14-10-2018 IPR038384 Formate dehydrogenase, C-terminal domain superfamily TSH58p_20680 c2402927883b919bc7a966495303a170 120 SMART SM00448 5 113 2.0E-13 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_20680 c2402927883b919bc7a966495303a170 120 SUPERFAMILY SSF52172 5 118 2.99E-25 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_20680 c2402927883b919bc7a966495303a170 120 Pfam PF00072 Response regulator receiver domain 7 113 5.1E-18 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_20680 c2402927883b919bc7a966495303a170 120 Gene3D G3DSA:3.40.50.2300 1 119 6.6E-24 T 14-10-2018 TSH58p_10885 f6b2d4f841dddb35fb3e8fa3c8e55c03 632 Pfam PF00005 ABC transporter 26 194 6.5E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_10885 f6b2d4f841dddb35fb3e8fa3c8e55c03 632 SUPERFAMILY SSF52540 5 265 2.19E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_10885 f6b2d4f841dddb35fb3e8fa3c8e55c03 632 Pfam PF00005 ABC transporter 342 496 3.2E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_10885 f6b2d4f841dddb35fb3e8fa3c8e55c03 632 SMART SM00382 34 244 1.1E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_10885 f6b2d4f841dddb35fb3e8fa3c8e55c03 632 SMART SM00382 350 546 1.4E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_10885 f6b2d4f841dddb35fb3e8fa3c8e55c03 632 SUPERFAMILY SSF52540 313 568 2.54E-72 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_10885 f6b2d4f841dddb35fb3e8fa3c8e55c03 632 Gene3D G3DSA:3.40.50.300 311 628 3.3E-89 T 14-10-2018 TSH58p_10885 f6b2d4f841dddb35fb3e8fa3c8e55c03 632 Gene3D G3DSA:3.40.50.300 3 293 2.7E-81 T 14-10-2018 TSH58p_10885 f6b2d4f841dddb35fb3e8fa3c8e55c03 632 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 246 284 1.4E-6 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_10885 f6b2d4f841dddb35fb3e8fa3c8e55c03 632 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 548 580 7.9E-9 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_10885 f6b2d4f841dddb35fb3e8fa3c8e55c03 632 ProSitePatterns PS00211 ABC transporters family signature. 469 483 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_31070 9c59ac7c4a8da4ada0ce4a766abbcd4b 409 Pfam PF07690 Major Facilitator Superfamily 19 221 4.5E-11 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_31070 9c59ac7c4a8da4ada0ce4a766abbcd4b 409 Gene3D G3DSA:1.20.1250.20 207 381 5.9E-11 T 14-10-2018 TSH58p_31070 9c59ac7c4a8da4ada0ce4a766abbcd4b 409 Gene3D G3DSA:1.20.1250.20 6 196 4.5E-14 T 14-10-2018 TSH58p_31070 9c59ac7c4a8da4ada0ce4a766abbcd4b 409 SUPERFAMILY SSF103473 9 387 1.44E-39 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_10955 ff2de7054d9677cb1c6c7cd3722956df 235 Gene3D G3DSA:3.20.20.10 11 233 2.4E-79 T 14-10-2018 IPR029066 PLP-binding barrel TSH58p_10955 ff2de7054d9677cb1c6c7cd3722956df 235 PIRSF PIRSF004848 8 234 2.0E-62 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 TSH58p_10955 ff2de7054d9677cb1c6c7cd3722956df 235 SUPERFAMILY SSF51419 12 227 9.89E-72 T 14-10-2018 IPR029066 PLP-binding barrel TSH58p_10955 ff2de7054d9677cb1c6c7cd3722956df 235 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 15 229 1.8E-51 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 TSH58p_10955 ff2de7054d9677cb1c6c7cd3722956df 235 Pfam PF01168 Alanine racemase, N-terminal domain 33 230 5.4E-28 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSH58p_10955 ff2de7054d9677cb1c6c7cd3722956df 235 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 15 228 26.264 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 TSH58p_07210 76651f835835e63b110c5c1ca24426a6 112 Pfam PF05521 Phage head-tail joining protein 13 105 2.2E-17 T 14-10-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor TSH58p_07210 76651f835835e63b110c5c1ca24426a6 112 TIGRFAM TIGR01563 gp16_SPP1: putative phage head-tail adaptor 11 104 9.4E-11 T 14-10-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor TSH58p_07210 76651f835835e63b110c5c1ca24426a6 112 Gene3D G3DSA:2.40.10.270 7 111 4.3E-20 T 14-10-2018 IPR038666 Bacteriophage SPP1, head-tail adaptor superfamily TSH58p_22925 3b49c0f2c576270a9fa8cfda5198d868 237 Pfam PF00005 ABC transporter 21 165 7.1E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_22925 3b49c0f2c576270a9fa8cfda5198d868 237 SUPERFAMILY SSF52540 5 234 1.52E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_22925 3b49c0f2c576270a9fa8cfda5198d868 237 Gene3D G3DSA:3.40.50.300 1 237 3.4E-52 T 14-10-2018 TSH58p_22925 3b49c0f2c576270a9fa8cfda5198d868 237 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_21190 64961e76b8d402aa368db5d793f4eb41 250 Gene3D G3DSA:3.40.50.850 33 239 2.4E-22 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TSH58p_21190 64961e76b8d402aa368db5d793f4eb41 250 Pfam PF00857 Isochorismatase family 33 212 3.4E-23 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 TSH58p_21190 64961e76b8d402aa368db5d793f4eb41 250 SUPERFAMILY SSF52499 33 247 3.01E-21 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TSH58p_27050 7962c7111e606c231346cb1bb2aa532b 656 Gene3D G3DSA:3.10.310.70 121 233 2.9E-86 T 14-10-2018 TSH58p_27050 7962c7111e606c231346cb1bb2aa532b 656 Gene3D G3DSA:3.20.20.140 102 533 2.9E-86 T 14-10-2018 TSH58p_27050 7962c7111e606c231346cb1bb2aa532b 656 SUPERFAMILY SSF51338 41 576 9.72E-22 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_27050 7962c7111e606c231346cb1bb2aa532b 656 Pfam PF07969 Amidohydrolase family 91 574 4.1E-117 T 14-10-2018 IPR013108 Amidohydrolase 3 TSH58p_27050 7962c7111e606c231346cb1bb2aa532b 656 Gene3D G3DSA:2.30.40.10 49 549 2.9E-86 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_27050 7962c7111e606c231346cb1bb2aa532b 656 SUPERFAMILY SSF51556 101 534 5.79E-43 T 14-10-2018 IPR032466 Metal-dependent hydrolase TSH58p_29640 e2ebaf6169334289f14788c17239a95c 294 Pfam PF09849 Uncharacterized protein conserved in bacteria (DUF2076) 1 291 9.5E-72 T 14-10-2018 IPR018648 Protein of unknown function DUF2076 TSH58p_13455 35ee28d750459fbb7d48cb914f7158d7 545 Pfam PF00005 ABC transporter 307 457 8.8E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_13455 35ee28d750459fbb7d48cb914f7158d7 545 Pfam PF00005 ABC transporter 30 188 2.6E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_13455 35ee28d750459fbb7d48cb914f7158d7 545 Gene3D G3DSA:3.40.50.300 7 278 2.1E-87 T 14-10-2018 TSH58p_13455 35ee28d750459fbb7d48cb914f7158d7 545 Gene3D G3DSA:3.40.50.300 279 544 2.0E-84 T 14-10-2018 TSH58p_13455 35ee28d750459fbb7d48cb914f7158d7 545 ProSitePatterns PS00211 ABC transporters family signature. 429 443 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_13455 35ee28d750459fbb7d48cb914f7158d7 545 SMART SM00382 38 238 6.6E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_13455 35ee28d750459fbb7d48cb914f7158d7 545 SMART SM00382 315 506 2.3E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_13455 35ee28d750459fbb7d48cb914f7158d7 545 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_13455 35ee28d750459fbb7d48cb914f7158d7 545 SUPERFAMILY SSF52540 9 260 3.11E-71 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_13455 35ee28d750459fbb7d48cb914f7158d7 545 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 240 270 5.8E-6 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_13455 35ee28d750459fbb7d48cb914f7158d7 545 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 508 540 4.8E-4 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_13455 35ee28d750459fbb7d48cb914f7158d7 545 SUPERFAMILY SSF52540 281 528 1.66E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_13710 78e3124770bfd4b686ca6902487fe80c 146 SUPERFAMILY SSF81301 32 134 4.58E-35 T 14-10-2018 TSH58p_13710 78e3124770bfd4b686ca6902487fe80c 146 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 28 133 24.564 T 14-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS TSH58p_13710 78e3124770bfd4b686ca6902487fe80c 146 Pfam PF02410 Ribosomal silencing factor during starvation 40 132 2.2E-27 T 14-10-2018 TSH58p_13710 78e3124770bfd4b686ca6902487fe80c 146 Gene3D G3DSA:3.30.460.10 30 144 7.0E-38 T 14-10-2018 TSH58p_13710 78e3124770bfd4b686ca6902487fe80c 146 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 36 132 5.5E-34 T 14-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS TSH58p_11185 dff7002c21ef1f3eae5f07ea61418896 190 SMART SM00463 97 183 3.5E-8 T 14-10-2018 IPR002625 Smr domain TSH58p_11185 dff7002c21ef1f3eae5f07ea61418896 190 SUPERFAMILY SSF160443 98 183 6.02E-17 T 14-10-2018 IPR036063 Smr domain superfamily TSH58p_11185 dff7002c21ef1f3eae5f07ea61418896 190 Gene3D G3DSA:3.30.1370.110 68 188 6.1E-40 T 14-10-2018 TSH58p_11185 dff7002c21ef1f3eae5f07ea61418896 190 Pfam PF01713 Smr domain 100 183 6.2E-26 T 14-10-2018 IPR002625 Smr domain TSH58p_05495 4c1fcf5b523b912c51a0b65ff1a79c9c 563 Gene3D G3DSA:3.40.50.300 307 547 4.1E-53 T 14-10-2018 TSH58p_05495 4c1fcf5b523b912c51a0b65ff1a79c9c 563 Pfam PF00005 ABC transporter 336 484 3.5E-18 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_05495 4c1fcf5b523b912c51a0b65ff1a79c9c 563 Pfam PF00664 ABC transporter transmembrane region 15 269 1.5E-7 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TSH58p_05495 4c1fcf5b523b912c51a0b65ff1a79c9c 563 Gene3D G3DSA:1.20.1560.10 5 302 2.3E-27 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_05495 4c1fcf5b523b912c51a0b65ff1a79c9c 563 SUPERFAMILY SSF90123 8 308 2.22E-34 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_05495 4c1fcf5b523b912c51a0b65ff1a79c9c 563 SUPERFAMILY SSF52540 310 535 4.0E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_05495 4c1fcf5b523b912c51a0b65ff1a79c9c 563 SMART SM00382 345 531 3.5E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_26955 a53b664056415cd498e29e54e49ed04d 364 SUPERFAMILY SSF53850 160 305 1.52E-6 T 14-10-2018 TSH58p_26955 a53b664056415cd498e29e54e49ed04d 364 Gene3D G3DSA:3.40.190.10 153 323 1.5E-129 T 14-10-2018 TSH58p_26955 a53b664056415cd498e29e54e49ed04d 364 PIRSF PIRSF039026 1 358 4.6E-127 T 14-10-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like TSH58p_26955 a53b664056415cd498e29e54e49ed04d 364 Gene3D G3DSA:3.40.190.170 33 337 1.5E-129 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily TSH58p_26955 a53b664056415cd498e29e54e49ed04d 364 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 39 323 3.0E-58 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 TSH58p_00145 b661dcc52883c7d279aba1f1bf7a4923 583 Pfam PF13583 Metallo-peptidase family M12B Reprolysin-like 156 204 8.3E-5 T 14-10-2018 TSH58p_00145 b661dcc52883c7d279aba1f1bf7a4923 583 Gene3D G3DSA:2.150.10.10 293 421 2.9E-14 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_00145 b661dcc52883c7d279aba1f1bf7a4923 583 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 316 334 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_00145 b661dcc52883c7d279aba1f1bf7a4923 583 SMART SM00235 63 225 2.4E-6 T 14-10-2018 IPR006026 Peptidase, metallopeptidase GO:0006508|GO:0008237|GO:0008270 TSH58p_00145 b661dcc52883c7d279aba1f1bf7a4923 583 SUPERFAMILY SSF55486 68 223 1.96E-31 T 14-10-2018 TSH58p_00145 b661dcc52883c7d279aba1f1bf7a4923 583 SUPERFAMILY SSF51120 365 529 2.88E-12 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_00145 b661dcc52883c7d279aba1f1bf7a4923 583 Gene3D G3DSA:3.40.390.10 48 226 2.3E-39 T 14-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 TSH58p_00145 b661dcc52883c7d279aba1f1bf7a4923 583 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 325 343 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_00145 b661dcc52883c7d279aba1f1bf7a4923 583 PRINTS PR00313 NodO calcium binding signature 483 492 4.1E-9 T 14-10-2018 TSH58p_00145 b661dcc52883c7d279aba1f1bf7a4923 583 PRINTS PR00313 NodO calcium binding signature 329 337 4.1E-9 T 14-10-2018 TSH58p_00145 b661dcc52883c7d279aba1f1bf7a4923 583 PRINTS PR00313 NodO calcium binding signature 465 473 4.1E-9 T 14-10-2018 TSH58p_00145 b661dcc52883c7d279aba1f1bf7a4923 583 PRINTS PR00313 NodO calcium binding signature 317 328 4.1E-9 T 14-10-2018 TSH58p_00145 b661dcc52883c7d279aba1f1bf7a4923 583 SUPERFAMILY SSF51120 231 391 3.53E-20 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_00145 b661dcc52883c7d279aba1f1bf7a4923 583 Gene3D G3DSA:2.150.10.10 422 562 1.1E-11 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_17220 169a881ddce49231b0eda0546b52ec1c 170 Gene3D G3DSA:1.20.1260.10 1 164 6.1E-66 T 14-10-2018 IPR012347 Ferritin-like TSH58p_17220 169a881ddce49231b0eda0546b52ec1c 170 SUPERFAMILY SSF47240 1 152 5.8E-55 T 14-10-2018 IPR009078 Ferritin-like superfamily TSH58p_17220 169a881ddce49231b0eda0546b52ec1c 170 Pfam PF05974 Domain of unknown function (DUF892) 5 161 1.7E-60 T 14-10-2018 IPR010287 Domain of unknown function DUF892 TSH58p_05800 47c5bcde9cd855f35b875b30f4714716 415 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 6 415 2.1E-150 T 14-10-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 TSH58p_05800 47c5bcde9cd855f35b875b30f4714716 415 Pfam PF12704 MacB-like periplasmic core domain 30 244 9.8E-21 T 14-10-2018 IPR025857 MacB-like periplasmic core domain TSH58p_05800 47c5bcde9cd855f35b875b30f4714716 415 Pfam PF02687 FtsX-like permease family 301 408 3.5E-12 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 TSH58p_21425 c18c902ee88587c1d9095f145bb9e2f9 329 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 35 313 6.2E-89 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 TSH58p_21425 c18c902ee88587c1d9095f145bb9e2f9 329 PIRSF PIRSF006470 1 328 1.6E-97 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 TSH58p_21425 c18c902ee88587c1d9095f145bb9e2f9 329 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 40 282 4.1E-71 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 TSH58p_21425 c18c902ee88587c1d9095f145bb9e2f9 329 Gene3D G3DSA:3.40.190.170 29 329 6.7E-117 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily TSH58p_21425 c18c902ee88587c1d9095f145bb9e2f9 329 SUPERFAMILY SSF53850 133 227 3.17E-6 T 14-10-2018 TSH58p_04940 0b89d6c93221554562d083892fbcfc86 156 Pfam PF11736 Protein of unknown function (DUF3299) 68 141 1.7E-4 T 14-10-2018 IPR021727 Protein of unknown function DUF3299 TSH58p_04940 0b89d6c93221554562d083892fbcfc86 156 Gene3D G3DSA:2.40.50.870 37 153 1.3E-6 T 14-10-2018 TSH58p_32330 77dddbc6991f95e5f705b5d7b6ac9bcc 375 SUPERFAMILY SSF51905 4 369 3.88E-58 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_32330 77dddbc6991f95e5f705b5d7b6ac9bcc 375 Gene3D G3DSA:3.30.9.10 84 313 1.8E-94 T 14-10-2018 TSH58p_32330 77dddbc6991f95e5f705b5d7b6ac9bcc 375 Gene3D G3DSA:3.50.50.60 5 356 1.8E-94 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_32330 77dddbc6991f95e5f705b5d7b6ac9bcc 375 Pfam PF01266 FAD dependent oxidoreductase 5 350 9.8E-61 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TSH58p_29710 b2d9eb80f6d4fb4e2c098944a337252d 471 PIRSF PIRSF019381 7 471 1.5E-160 T 14-10-2018 IPR007413 Protein of unknown function DUF463, YcjX-like protein TSH58p_29710 b2d9eb80f6d4fb4e2c098944a337252d 471 Pfam PF04317 YcjX-like family, DUF463 33 470 1.3E-166 T 14-10-2018 IPR007413 Protein of unknown function DUF463, YcjX-like protein TSH58p_02570 93636f4a271debcc4fc2ea1c1cdbcace 435 Gene3D G3DSA:1.20.1250.20 26 435 1.4E-36 T 14-10-2018 TSH58p_02570 93636f4a271debcc4fc2ea1c1cdbcace 435 ProSitePatterns PS00216 Sugar transport proteins signature 1. 308 325 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TSH58p_02570 93636f4a271debcc4fc2ea1c1cdbcace 435 Pfam PF07690 Major Facilitator Superfamily 67 397 1.7E-18 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_02570 93636f4a271debcc4fc2ea1c1cdbcace 435 SUPERFAMILY SSF103473 27 429 2.09E-37 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_31235 6578872c192efb3d06cf04709db1650b 571 Gene3D G3DSA:3.30.450.20 50 192 4.4E-7 T 14-10-2018 TSH58p_31235 6578872c192efb3d06cf04709db1650b 571 Gene3D G3DSA:3.30.450.20 353 428 5.1E-6 T 14-10-2018 TSH58p_31235 6578872c192efb3d06cf04709db1650b 571 SMART SM00387 473 566 0.0024 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_31235 6578872c192efb3d06cf04709db1650b 571 SUPERFAMILY SSF55874 441 539 2.01E-8 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_31235 6578872c192efb3d06cf04709db1650b 571 Pfam PF07568 Histidine kinase 376 449 9.5E-18 T 14-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain TSH58p_31235 6578872c192efb3d06cf04709db1650b 571 Gene3D G3DSA:3.30.565.10 432 567 1.1E-16 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_01095 3c2efbdc7571825ddb5e8fa116f78dd7 387 TIGRFAM TIGR03871 ABC_peri_MoxJ_2: quinoprotein dehydrogenase-associated probable ABC transporter substrate-binding protein 2 214 2.4E-76 T 14-10-2018 IPR022448 Quinoprotein dehydrogenase-associated TSH58p_01095 3c2efbdc7571825ddb5e8fa116f78dd7 387 Gene3D G3DSA:3.40.190.10 2 207 1.9E-16 T 14-10-2018 TSH58p_01095 3c2efbdc7571825ddb5e8fa116f78dd7 387 Gene3D G3DSA:3.40.250.10 241 380 1.9E-11 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily TSH58p_01095 3c2efbdc7571825ddb5e8fa116f78dd7 387 SUPERFAMILY SSF52821 249 380 6.55E-17 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily TSH58p_01095 3c2efbdc7571825ddb5e8fa116f78dd7 387 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 2 209 2.4E-18 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_01095 3c2efbdc7571825ddb5e8fa116f78dd7 387 TIGRFAM TIGR03865 PQQ_CXXCW: PQQ-dependent catabolism-associated CXXCW motif protein 221 380 9.3E-59 T 14-10-2018 IPR022376 PQQ-dependent catabolism-associated CXXCW motif TSH58p_01095 3c2efbdc7571825ddb5e8fa116f78dd7 387 SMART SM00062 1 213 7.9E-22 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_01095 3c2efbdc7571825ddb5e8fa116f78dd7 387 Gene3D G3DSA:3.40.190.10 62 177 1.9E-16 T 14-10-2018 TSH58p_01095 3c2efbdc7571825ddb5e8fa116f78dd7 387 SUPERFAMILY SSF53850 2 209 8.69E-24 T 14-10-2018 TSH58p_30425 027cf55cc8b4488e81a2a497bb2f33aa 121 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 35 104 9.4E-19 T 14-10-2018 TSH58p_30425 027cf55cc8b4488e81a2a497bb2f33aa 121 SUPERFAMILY SSF54292 35 104 6.03E-13 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TSH58p_30425 027cf55cc8b4488e81a2a497bb2f33aa 121 Gene3D G3DSA:3.10.20.440 17 108 6.7E-15 T 14-10-2018 TSH58p_00600 3ab351327a8a15956289206e01c64534 376 Gene3D G3DSA:3.30.70.360 168 284 6.3E-97 T 14-10-2018 TSH58p_00600 3ab351327a8a15956289206e01c64534 376 Pfam PF07687 Peptidase dimerisation domain 165 271 2.0E-17 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain TSH58p_00600 3ab351327a8a15956289206e01c64534 376 Gene3D G3DSA:3.40.630.10 5 360 6.3E-97 T 14-10-2018 TSH58p_00600 3ab351327a8a15956289206e01c64534 376 SUPERFAMILY SSF55031 168 274 1.5E-17 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TSH58p_00600 3ab351327a8a15956289206e01c64534 376 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 2 371 1.6E-127 T 14-10-2018 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 TSH58p_00600 3ab351327a8a15956289206e01c64534 376 Pfam PF01546 Peptidase family M20/M25/M40 61 372 1.2E-33 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 TSH58p_00600 3ab351327a8a15956289206e01c64534 376 SUPERFAMILY SSF53187 3 375 7.07E-57 T 14-10-2018 TSH58p_00600 3ab351327a8a15956289206e01c64534 376 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 94 131 - T 14-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 TSH58p_17850 7142fd00129df5230150f23886f70ead 791 Pfam PF00534 Glycosyl transferases group 1 529 663 9.7E-14 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 TSH58p_17850 7142fd00129df5230150f23886f70ead 791 SUPERFAMILY SSF53448 98 211 2.36E-8 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_17850 7142fd00129df5230150f23886f70ead 791 Gene3D G3DSA:3.40.50.2000 508 684 2.5E-29 T 14-10-2018 TSH58p_17850 7142fd00129df5230150f23886f70ead 791 Gene3D G3DSA:3.40.50.2000 463 697 2.5E-29 T 14-10-2018 TSH58p_17850 7142fd00129df5230150f23886f70ead 791 SUPERFAMILY SSF53756 349 699 1.47E-43 T 14-10-2018 TSH58p_07030 077a4c5d15bdc596e02d9d1097f6d9e5 139 Gene3D G3DSA:2.60.120.460 1 139 3.8E-43 T 14-10-2018 IPR035917 YjbQ-like superfamily TSH58p_07030 077a4c5d15bdc596e02d9d1097f6d9e5 139 PIRSF PIRSF004681 1 139 1.2E-50 T 14-10-2018 IPR001602 Uncharacterised protein family UPF0047 TSH58p_07030 077a4c5d15bdc596e02d9d1097f6d9e5 139 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 8 139 1.9E-43 T 14-10-2018 IPR001602 Uncharacterised protein family UPF0047 TSH58p_07030 077a4c5d15bdc596e02d9d1097f6d9e5 139 SUPERFAMILY SSF111038 1 139 1.57E-48 T 14-10-2018 IPR035917 YjbQ-like superfamily TSH58p_07030 077a4c5d15bdc596e02d9d1097f6d9e5 139 Pfam PF01894 Uncharacterised protein family UPF0047 19 135 2.7E-40 T 14-10-2018 IPR001602 Uncharacterised protein family UPF0047 TSH58p_18495 527d25b27f1640fc10f760e8c65cc5e3 153 Gene3D G3DSA:3.40.50.2000 2 110 6.5E-15 T 14-10-2018 TSH58p_18495 527d25b27f1640fc10f760e8c65cc5e3 153 SUPERFAMILY SSF53756 5 125 4.4E-14 T 14-10-2018 TSH58p_18495 527d25b27f1640fc10f760e8c65cc5e3 153 Pfam PF13524 Glycosyl transferases group 1 37 118 1.2E-9 T 14-10-2018 TSH58p_31825 e6253e0a8da77c1aaf36e8410ce12016 297 SUPERFAMILY SSF51621 13 293 4.31E-93 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSH58p_31825 e6253e0a8da77c1aaf36e8410ce12016 297 Gene3D G3DSA:3.20.20.60 13 296 6.3E-103 T 14-10-2018 TSH58p_31825 e6253e0a8da77c1aaf36e8410ce12016 297 Pfam PF13714 Phosphoenolpyruvate phosphomutase 17 259 7.8E-53 T 14-10-2018 TSH58p_18350 f5650a9c22746749d4d7b1ff8746399a 373 Gene3D G3DSA:3.30.9.10 86 326 2.4E-134 T 14-10-2018 TSH58p_18350 f5650a9c22746749d4d7b1ff8746399a 373 Pfam PF01266 FAD dependent oxidoreductase 5 370 6.7E-60 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TSH58p_18350 f5650a9c22746749d4d7b1ff8746399a 373 Gene3D G3DSA:3.50.50.60 5 364 2.4E-134 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_18350 f5650a9c22746749d4d7b1ff8746399a 373 SUPERFAMILY SSF51905 4 371 1.04E-38 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_26000 47d9b7d8b3531ddafc14256ebf7ffa70 189 Gene3D G3DSA:1.20.910.10 2 187 7.6E-38 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 TSH58p_26000 47d9b7d8b3531ddafc14256ebf7ffa70 189 SUPERFAMILY SSF48613 4 180 1.53E-34 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 TSH58p_15095 46e75326e61f56c698f0b27890a71756 65 Gene3D G3DSA:1.20.5.1030 4 60 1.9E-15 T 14-10-2018 IPR038379 SecE superfamily TSH58p_15095 46e75326e61f56c698f0b27890a71756 65 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 8 60 1.0E-17 T 14-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSH58p_15095 46e75326e61f56c698f0b27890a71756 65 Hamap MF_00422 Protein translocase subunit SecE [secE]. 4 60 12.119 T 14-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSH58p_15095 46e75326e61f56c698f0b27890a71756 65 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 8 61 1.9E-17 T 14-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 TSH58p_11145 a9b66ecafa9cbc6c7294723fa1403156 214 SUPERFAMILY SSF52317 3 203 2.72E-55 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_11145 a9b66ecafa9cbc6c7294723fa1403156 214 Gene3D G3DSA:3.40.50.880 1 213 9.1E-72 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_11145 a9b66ecafa9cbc6c7294723fa1403156 214 PIRSF PIRSF000495 2 214 4.6E-69 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 TSH58p_11145 a9b66ecafa9cbc6c7294723fa1403156 214 Pfam PF00117 Glutamine amidotransferase class-I 15 209 2.1E-22 T 14-10-2018 IPR017926 Glutamine amidotransferase TSH58p_11145 a9b66ecafa9cbc6c7294723fa1403156 214 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 4 211 1.7E-67 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 TSH58p_11145 a9b66ecafa9cbc6c7294723fa1403156 214 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 3 212 36.185 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 TSH58p_14730 df5215a17155f7f11ce104ec8446fc74 451 SUPERFAMILY SSF111283 11 450 1.23E-128 T 14-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TSH58p_14730 df5215a17155f7f11ce104ec8446fc74 451 Pfam PF01523 Putative modulator of DNA gyrase 30 320 5.8E-58 T 14-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TSH58p_14730 df5215a17155f7f11ce104ec8446fc74 451 Gene3D G3DSA:3.30.2290.10 2 228 2.8E-75 T 14-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TSH58p_15195 19c086a60f6803c788ac2b887a82de88 258 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 1.3E-39 T 14-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15195 19c086a60f6803c788ac2b887a82de88 258 SUPERFAMILY SSF54814 2 105 1.44E-37 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TSH58p_15195 19c086a60f6803c788ac2b887a82de88 258 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 1.6E-93 T 14-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 TSH58p_15195 19c086a60f6803c788ac2b887a82de88 258 Gene3D G3DSA:3.30.1140.32 107 207 3.4E-44 T 14-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15195 19c086a60f6803c788ac2b887a82de88 258 Pfam PF07650 KH domain 38 109 1.3E-18 T 14-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15195 19c086a60f6803c788ac2b887a82de88 258 Gene3D G3DSA:3.30.300.20 17 106 2.9E-28 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta TSH58p_15195 19c086a60f6803c788ac2b887a82de88 258 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 14-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15195 19c086a60f6803c788ac2b887a82de88 258 SMART SM00322 59 124 9.8E-7 T 14-10-2018 IPR004087 K Homology domain GO:0003676 TSH58p_15195 19c086a60f6803c788ac2b887a82de88 258 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 39.137 T 14-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 TSH58p_15195 19c086a60f6803c788ac2b887a82de88 258 SUPERFAMILY SSF54821 107 205 5.89E-40 T 14-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_18955 89eec627990e8df5b2a8dd9d42c24a00 398 TIGRFAM TIGR00695 uxuA: mannonate dehydratase 1 393 2.9E-154 T 14-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 TSH58p_18955 89eec627990e8df5b2a8dd9d42c24a00 398 SUPERFAMILY SSF51658 1 388 2.49E-77 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily TSH58p_18955 89eec627990e8df5b2a8dd9d42c24a00 398 Hamap MF_00106 Mannonate dehydratase [uxuA]. 1 398 185.634 T 14-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 TSH58p_18955 89eec627990e8df5b2a8dd9d42c24a00 398 PIRSF PIRSF016049 1 396 1.2E-163 T 14-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 TSH58p_18955 89eec627990e8df5b2a8dd9d42c24a00 398 Pfam PF03786 D-mannonate dehydratase (UxuA) 1 391 1.5E-126 T 14-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 TSH58p_23150 e9a1c2766e496d7733817b94cdfa23cd 146 PIRSF PIRSF018267 6 144 9.9E-50 T 14-10-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 TSH58p_23150 e9a1c2766e496d7733817b94cdfa23cd 146 TIGRFAM TIGR00632 vsr: DNA mismatch endonuclease Vsr 14 126 1.9E-39 T 14-10-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 TSH58p_23150 e9a1c2766e496d7733817b94cdfa23cd 146 Gene3D G3DSA:3.40.960.10 28 143 3.9E-45 T 14-10-2018 TSH58p_23150 e9a1c2766e496d7733817b94cdfa23cd 146 SUPERFAMILY SSF52980 16 132 9.12E-46 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TSH58p_23150 e9a1c2766e496d7733817b94cdfa23cd 146 Pfam PF03852 DNA mismatch endonuclease Vsr 16 79 4.1E-29 T 14-10-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 TSH58p_24190 6a26a1e2769126d72e6439a4ff401a99 289 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 277 1.9E-39 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_19740 e0d4fd03ed18441f429459d7400c636f 340 SUPERFAMILY SSF47413 2 55 2.82E-6 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_19740 e0d4fd03ed18441f429459d7400c636f 340 SUPERFAMILY SSF52540 73 331 5.02E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_19740 e0d4fd03ed18441f429459d7400c636f 340 Pfam PF13560 Helix-turn-helix domain 3 56 2.1E-7 T 14-10-2018 TSH58p_19740 e0d4fd03ed18441f429459d7400c636f 340 Pfam PF13614 AAA domain 72 254 2.4E-53 T 14-10-2018 IPR025669 AAA domain TSH58p_19740 e0d4fd03ed18441f429459d7400c636f 340 Gene3D G3DSA:3.40.50.300 68 337 2.8E-65 T 14-10-2018 TSH58p_19740 e0d4fd03ed18441f429459d7400c636f 340 Gene3D G3DSA:1.10.260.40 1 66 1.3E-6 T 14-10-2018 TSH58p_11395 1ab03c7182129d1a32a719d1ba76f0d5 239 SUPERFAMILY SSF55315 119 204 1.2E-8 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like TSH58p_11395 1ab03c7182129d1a32a719d1ba76f0d5 239 Pfam PF04296 Protein of unknown function (DUF448) 38 113 5.3E-21 T 14-10-2018 IPR007393 Domain of unknown function DUF448 TSH58p_11395 1ab03c7182129d1a32a719d1ba76f0d5 239 Gene3D G3DSA:3.30.1230.10 31 119 7.5E-18 T 14-10-2018 IPR035931 YlxR-like superfamily TSH58p_11395 1ab03c7182129d1a32a719d1ba76f0d5 239 Gene3D G3DSA:3.30.1330.30 120 216 4.5E-9 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like TSH58p_11395 1ab03c7182129d1a32a719d1ba76f0d5 239 SUPERFAMILY SSF64376 34 122 9.55E-24 T 14-10-2018 IPR035931 YlxR-like superfamily TSH58p_11305 a973e819c145f304184753143e9ff1a5 188 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 1 176 26.849 T 14-10-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 TSH58p_11305 a973e819c145f304184753143e9ff1a5 188 Gene3D G3DSA:3.30.1380.10 2 171 1.9E-46 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSH58p_11305 a973e819c145f304184753143e9ff1a5 188 PIRSF PIRSF026671 2 178 4.1E-50 T 14-10-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 TSH58p_11305 a973e819c145f304184753143e9ff1a5 188 Pfam PF01427 D-ala-D-ala dipeptidase 11 174 4.6E-45 T 14-10-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 TSH58p_11305 a973e819c145f304184753143e9ff1a5 188 SUPERFAMILY SSF55166 3 167 3.66E-55 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSH58p_05735 b0d6552f3c82cb8399373051531b5f4c 377 SUPERFAMILY SSF50156 101 207 1.58E-19 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 TSH58p_05735 b0d6552f3c82cb8399373051531b5f4c 377 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 144 184 2.6E-7 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_05735 b0d6552f3c82cb8399373051531b5f4c 377 Pfam PF02163 Peptidase family M50 14 354 3.2E-76 T 14-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TSH58p_05735 b0d6552f3c82cb8399373051531b5f4c 377 Gene3D G3DSA:2.30.42.10 141 231 4.6E-21 T 14-10-2018 TSH58p_05735 b0d6552f3c82cb8399373051531b5f4c 377 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 145 366 1.5E-48 T 14-10-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 TSH58p_05735 b0d6552f3c82cb8399373051531b5f4c 377 SMART SM00228 119 198 2.8E-10 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_00405 efd2e0bc9652cc17ee7113340e114c44 555 SUPERFAMILY SSF56801 135 550 1.09E-82 T 14-10-2018 TSH58p_00405 efd2e0bc9652cc17ee7113340e114c44 555 SUPERFAMILY SSF46785 20 92 1.71E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_00405 efd2e0bc9652cc17ee7113340e114c44 555 SMART SM00346 19 96 7.8E-10 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TSH58p_00405 efd2e0bc9652cc17ee7113340e114c44 555 Pfam PF00501 AMP-binding enzyme 138 551 4.8E-66 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_00405 efd2e0bc9652cc17ee7113340e114c44 555 Pfam PF09339 IclR helix-turn-helix domain 21 73 3.9E-12 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TSH58p_00405 efd2e0bc9652cc17ee7113340e114c44 555 Gene3D G3DSA:1.10.10.10 19 82 2.1E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_00405 efd2e0bc9652cc17ee7113340e114c44 555 Gene3D G3DSA:3.40.50.12780 123 545 2.0E-87 T 14-10-2018 TSH58p_02345 bb6b82c33c2bd5d88a1b4d615d6e87a4 496 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 3 127 8.1E-34 T 14-10-2018 IPR000014 PAS domain TSH58p_02345 bb6b82c33c2bd5d88a1b4d615d6e87a4 496 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 128 255 1.2E-35 T 14-10-2018 IPR000014 PAS domain TSH58p_02345 bb6b82c33c2bd5d88a1b4d615d6e87a4 496 SMART SM00091 2 68 6.8E-15 T 14-10-2018 IPR000014 PAS domain TSH58p_02345 bb6b82c33c2bd5d88a1b4d615d6e87a4 496 SMART SM00091 132 198 9.9E-12 T 14-10-2018 IPR000014 PAS domain TSH58p_02345 bb6b82c33c2bd5d88a1b4d615d6e87a4 496 SUPERFAMILY SSF55874 346 488 3.01E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_02345 bb6b82c33c2bd5d88a1b4d615d6e87a4 496 SMART SM00086 208 248 34.0 T 14-10-2018 IPR001610 PAC motif TSH58p_02345 bb6b82c33c2bd5d88a1b4d615d6e87a4 496 SMART SM00086 78 120 0.5 T 14-10-2018 IPR001610 PAC motif TSH58p_02345 bb6b82c33c2bd5d88a1b4d615d6e87a4 496 Pfam PF00512 His Kinase A (phospho-acceptor) domain 271 333 1.2E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_02345 bb6b82c33c2bd5d88a1b4d615d6e87a4 496 SUPERFAMILY SSF55785 13 129 2.36E-33 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_02345 bb6b82c33c2bd5d88a1b4d615d6e87a4 496 SMART SM00388 270 339 1.9E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_02345 bb6b82c33c2bd5d88a1b4d615d6e87a4 496 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 382 489 1.9E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_02345 bb6b82c33c2bd5d88a1b4d615d6e87a4 496 SUPERFAMILY SSF47384 267 334 1.96E-9 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_02345 bb6b82c33c2bd5d88a1b4d615d6e87a4 496 Pfam PF00989 PAS fold 3 117 9.8E-18 T 14-10-2018 IPR013767 PAS fold GO:0006355 TSH58p_02345 bb6b82c33c2bd5d88a1b4d615d6e87a4 496 Pfam PF00989 PAS fold 133 244 2.6E-16 T 14-10-2018 IPR013767 PAS fold GO:0006355 TSH58p_02345 bb6b82c33c2bd5d88a1b4d615d6e87a4 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 437 2.0E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_02345 bb6b82c33c2bd5d88a1b4d615d6e87a4 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 475 488 2.0E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_02345 bb6b82c33c2bd5d88a1b4d615d6e87a4 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 451 2.0E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_02345 bb6b82c33c2bd5d88a1b4d615d6e87a4 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 452 470 2.0E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_02345 bb6b82c33c2bd5d88a1b4d615d6e87a4 496 SUPERFAMILY SSF55785 117 246 2.23E-29 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_02345 bb6b82c33c2bd5d88a1b4d615d6e87a4 496 SMART SM00387 381 491 1.7E-34 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_02345 bb6b82c33c2bd5d88a1b4d615d6e87a4 496 Gene3D G3DSA:1.10.287.130 249 335 3.5E-21 T 14-10-2018 TSH58p_02345 bb6b82c33c2bd5d88a1b4d615d6e87a4 496 Gene3D G3DSA:3.30.565.10 338 494 5.1E-41 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_02345 bb6b82c33c2bd5d88a1b4d615d6e87a4 496 Gene3D G3DSA:3.30.450.20 128 248 2.5E-35 T 14-10-2018 TSH58p_02345 bb6b82c33c2bd5d88a1b4d615d6e87a4 496 Gene3D G3DSA:3.30.450.20 1 123 1.7E-39 T 14-10-2018 TSH58p_32225 de565c81c240b597c542c78d5c767269 527 Pfam PF02397 Bacterial sugar transferase 334 519 8.2E-65 T 14-10-2018 IPR003362 Bacterial sugar transferase TSH58p_32225 de565c81c240b597c542c78d5c767269 527 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 73 524 6.8E-121 T 14-10-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase TSH58p_32225 de565c81c240b597c542c78d5c767269 527 SUPERFAMILY SSF51735 199 282 5.31E-6 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_32225 de565c81c240b597c542c78d5c767269 527 Pfam PF13727 CoA-binding domain 120 294 1.5E-21 T 14-10-2018 TSH58p_32225 de565c81c240b597c542c78d5c767269 527 Gene3D G3DSA:3.40.50.720 197 320 1.4E-12 T 14-10-2018 TSH58p_26895 e8bd6d8107b2f9da3dfc7ceabe01868f 376 SMART SM00382 30 213 1.9E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_26895 e8bd6d8107b2f9da3dfc7ceabe01868f 376 Gene3D G3DSA:2.40.50.140 289 331 3.2E-7 T 14-10-2018 TSH58p_26895 e8bd6d8107b2f9da3dfc7ceabe01868f 376 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_26895 e8bd6d8107b2f9da3dfc7ceabe01868f 376 Pfam PF00005 ABC transporter 25 163 7.0E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_26895 e8bd6d8107b2f9da3dfc7ceabe01868f 376 Gene3D G3DSA:2.40.50.940 225 288 3.2E-7 T 14-10-2018 TSH58p_26895 e8bd6d8107b2f9da3dfc7ceabe01868f 376 SUPERFAMILY SSF50331 238 359 1.13E-9 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSH58p_26895 e8bd6d8107b2f9da3dfc7ceabe01868f 376 Gene3D G3DSA:3.40.50.300 2 224 4.4E-67 T 14-10-2018 TSH58p_26895 e8bd6d8107b2f9da3dfc7ceabe01868f 376 SUPERFAMILY SSF52540 6 242 1.36E-85 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_26895 e8bd6d8107b2f9da3dfc7ceabe01868f 376 Pfam PF08402 TOBE domain 282 359 2.8E-8 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TSH58p_26895 e8bd6d8107b2f9da3dfc7ceabe01868f 376 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 36 360 2.9E-109 T 14-10-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 TSH58p_29070 d96504c5802163aa73965c5a684138dd 158 SUPERFAMILY SSF55154 1 148 1.8E-32 T 14-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 TSH58p_29070 d96504c5802163aa73965c5a684138dd 158 SMART SM01118 2 148 1.9E-14 T 14-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 TSH58p_29070 d96504c5802163aa73965c5a684138dd 158 Gene3D G3DSA:2.40.320.10 1 150 3.8E-39 T 14-10-2018 TSH58p_29070 d96504c5802163aa73965c5a684138dd 158 PIRSF PIRSF016487 1 158 2.0E-46 T 14-10-2018 IPR012042 Inorganic triphosphatase NeuTTM/CthTTM-like TSH58p_00650 6e09ccfcd7f8b0e6c6a7638ac88b26d9 530 Gene3D G3DSA:2.30.30.40 381 502 1.3E-26 T 14-10-2018 TSH58p_00650 6e09ccfcd7f8b0e6c6a7638ac88b26d9 530 Gene3D G3DSA:2.40.50.180 31 114 4.6E-18 T 14-10-2018 TSH58p_00650 6e09ccfcd7f8b0e6c6a7638ac88b26d9 530 Gene3D G3DSA:2.40.50.180 398 467 1.3E-26 T 14-10-2018 TSH58p_00650 6e09ccfcd7f8b0e6c6a7638ac88b26d9 530 Gene3D G3DSA:2.40.50.180 221 293 1.4E-23 T 14-10-2018 TSH58p_00650 6e09ccfcd7f8b0e6c6a7638ac88b26d9 530 Gene3D G3DSA:2.30.30.40 14 147 4.6E-18 T 14-10-2018 TSH58p_00650 6e09ccfcd7f8b0e6c6a7638ac88b26d9 530 SUPERFAMILY SSF50341 380 520 1.44E-28 T 14-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 TSH58p_00650 6e09ccfcd7f8b0e6c6a7638ac88b26d9 530 Gene3D G3DSA:2.30.30.40 204 331 1.4E-23 T 14-10-2018 TSH58p_00650 6e09ccfcd7f8b0e6c6a7638ac88b26d9 530 SMART SM00260 8 165 7.2E-19 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TSH58p_00650 6e09ccfcd7f8b0e6c6a7638ac88b26d9 530 SMART SM00260 375 518 7.4E-27 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TSH58p_00650 6e09ccfcd7f8b0e6c6a7638ac88b26d9 530 SMART SM00260 198 344 1.8E-27 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TSH58p_00650 6e09ccfcd7f8b0e6c6a7638ac88b26d9 530 SUPERFAMILY SSF50341 198 345 3.66E-25 T 14-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 TSH58p_00650 6e09ccfcd7f8b0e6c6a7638ac88b26d9 530 Pfam PF01584 CheW-like domain 202 346 9.8E-26 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TSH58p_00650 6e09ccfcd7f8b0e6c6a7638ac88b26d9 530 Pfam PF01584 CheW-like domain 380 520 2.0E-29 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TSH58p_00650 6e09ccfcd7f8b0e6c6a7638ac88b26d9 530 Pfam PF01584 CheW-like domain 13 167 2.8E-23 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TSH58p_00650 6e09ccfcd7f8b0e6c6a7638ac88b26d9 530 SUPERFAMILY SSF50341 10 167 6.67E-23 T 14-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 TSH58p_29425 c39ea2265f6360582bb5516a87c9e52b 162 SUPERFAMILY SSF89963 2 82 1.12E-24 T 14-10-2018 IPR036183 YajQ-like superfamily TSH58p_29425 c39ea2265f6360582bb5516a87c9e52b 162 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 1 162 25.914 T 14-10-2018 IPR007551 Protein of unknown function DUF520 TSH58p_29425 c39ea2265f6360582bb5516a87c9e52b 162 Gene3D G3DSA:3.30.70.990 9 99 1.1E-54 T 14-10-2018 IPR035570 UPF0234, N-terminal TSH58p_29425 c39ea2265f6360582bb5516a87c9e52b 162 Pfam PF04461 Protein of unknown function (DUF520) 2 161 1.5E-59 T 14-10-2018 IPR007551 Protein of unknown function DUF520 TSH58p_29425 c39ea2265f6360582bb5516a87c9e52b 162 SUPERFAMILY SSF89963 91 162 8.37E-28 T 14-10-2018 IPR036183 YajQ-like superfamily TSH58p_29425 c39ea2265f6360582bb5516a87c9e52b 162 Gene3D G3DSA:3.30.70.860 3 161 1.1E-54 T 14-10-2018 IPR035571 UPF0234-like, C-terminal TSH58p_10480 ba6940040b9a68a421cd1e8660a9909b 171 Pfam PF05974 Domain of unknown function (DUF892) 5 158 2.8E-43 T 14-10-2018 IPR010287 Domain of unknown function DUF892 TSH58p_10480 ba6940040b9a68a421cd1e8660a9909b 171 SUPERFAMILY SSF47240 3 157 1.08E-41 T 14-10-2018 IPR009078 Ferritin-like superfamily TSH58p_10480 ba6940040b9a68a421cd1e8660a9909b 171 Gene3D G3DSA:1.20.1260.10 1 171 3.9E-65 T 14-10-2018 IPR012347 Ferritin-like TSH58p_31245 3debec2decd0078e815452080ba5e060 181 Pfam PF12551 Poly-beta-hydroxybutyrate polymerase N terminal 63 93 7.7E-11 T 14-10-2018 IPR022211 Poly-beta-hydroxybutyrate polymerase N-terminal TSH58p_18645 423a043ccc13b9723ad23d06b6998e33 284 Gene3D G3DSA:3.90.550.20 33 187 5.1E-7 T 14-10-2018 TSH58p_18645 423a043ccc13b9723ad23d06b6998e33 284 Pfam PF04488 Glycosyltransferase sugar-binding region containing DXD motif 116 148 1.1E-7 T 14-10-2018 IPR007577 Glycosyltransferase, DXD sugar-binding motif TSH58p_18645 423a043ccc13b9723ad23d06b6998e33 284 SUPERFAMILY SSF53448 32 260 8.62E-15 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_25340 c5032ddc919b0f03891e5bc8194d4d11 1313 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 581 605 2.1E-8 T 14-10-2018 TSH58p_25340 c5032ddc919b0f03891e5bc8194d4d11 1313 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 550 562 2.1E-8 T 14-10-2018 TSH58p_25340 c5032ddc919b0f03891e5bc8194d4d11 1313 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 331 345 2.1E-8 T 14-10-2018 TSH58p_25340 c5032ddc919b0f03891e5bc8194d4d11 1313 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 553 559 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TSH58p_25340 c5032ddc919b0f03891e5bc8194d4d11 1313 Pfam PF07669 Eco57I restriction-modification methylase 550 640 9.4E-6 T 14-10-2018 IPR011639 Restriction modification methylase Eco57I GO:0003677|GO:0003824|GO:0006304 TSH58p_25340 c5032ddc919b0f03891e5bc8194d4d11 1313 SUPERFAMILY SSF53335 77 660 2.69E-46 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_21125 70756fd6a3bb507108ea49a22ef27c3b 453 Pfam PF00860 Permease family 22 397 2.1E-105 T 14-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 TSH58p_21125 70756fd6a3bb507108ea49a22ef27c3b 453 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 17 431 1.4E-120 T 14-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 TSH58p_21125 70756fd6a3bb507108ea49a22ef27c3b 453 TIGRFAM TIGR03173 pbuX: xanthine permease 25 434 5.7E-164 T 14-10-2018 IPR017588 Uric acid permease UacT-like GO:0016021|GO:0022857|GO:0055085 TSH58p_29435 037ba7cd2342c4160b1e6ba1596d1c09 336 Gene3D G3DSA:2.70.70.10 52 202 1.1E-32 T 14-10-2018 IPR011055 Duplicated hybrid motif TSH58p_29435 037ba7cd2342c4160b1e6ba1596d1c09 336 Pfam PF01551 Peptidase family M23 70 188 1.2E-22 T 14-10-2018 IPR016047 Peptidase M23 TSH58p_29435 037ba7cd2342c4160b1e6ba1596d1c09 336 SUPERFAMILY SSF51261 68 189 1.7E-28 T 14-10-2018 IPR011055 Duplicated hybrid motif TSH58p_06165 6906d7f9409642f6e69ee63961e2b001 415 Pfam PF03594 Benzoate membrane transport protein 17 404 7.4E-95 T 14-10-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 TSH58p_06165 6906d7f9409642f6e69ee63961e2b001 415 TIGRFAM TIGR00843 benE: benzoate transporter 21 402 2.5E-72 T 14-10-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 TSH58p_17725 edfd94a294369c0c430add9e069d9dab 793 Pfam PF06791 Prophage tail length tape measure protein 241 412 4.3E-12 T 14-10-2018 IPR009628 Bacteriophage lambda, GpH, tail tape measure, N-terminal TSH58p_24325 980ead8844982c5e1b1c82dc4baa6b12 619 Gene3D G3DSA:3.30.565.10 466 615 1.4E-28 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_24325 980ead8844982c5e1b1c82dc4baa6b12 619 SMART SM00387 505 614 1.3E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_24325 980ead8844982c5e1b1c82dc4baa6b12 619 Pfam PF00512 His Kinase A (phospho-acceptor) domain 399 460 1.3E-6 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_24325 980ead8844982c5e1b1c82dc4baa6b12 619 Gene3D G3DSA:1.10.287.130 390 462 2.0E-12 T 14-10-2018 TSH58p_24325 980ead8844982c5e1b1c82dc4baa6b12 619 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 510 611 2.3E-15 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_24325 980ead8844982c5e1b1c82dc4baa6b12 619 SUPERFAMILY SSF47384 383 461 6.47E-9 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_24325 980ead8844982c5e1b1c82dc4baa6b12 619 PRINTS PR00344 Bacterial sensor protein C-terminal signature 561 571 6.8E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_24325 980ead8844982c5e1b1c82dc4baa6b12 619 PRINTS PR00344 Bacterial sensor protein C-terminal signature 574 592 6.8E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_24325 980ead8844982c5e1b1c82dc4baa6b12 619 PRINTS PR00344 Bacterial sensor protein C-terminal signature 598 611 6.8E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_24325 980ead8844982c5e1b1c82dc4baa6b12 619 PRINTS PR00344 Bacterial sensor protein C-terminal signature 543 557 6.8E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_24325 980ead8844982c5e1b1c82dc4baa6b12 619 Pfam PF05231 MASE1 9 283 7.0E-13 T 14-10-2018 IPR007895 MASE1 TSH58p_24325 980ead8844982c5e1b1c82dc4baa6b12 619 SUPERFAMILY SSF55874 455 610 4.19E-28 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_24325 980ead8844982c5e1b1c82dc4baa6b12 619 SMART SM00388 397 464 5.9E-6 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_03045 c87651e06b45ffaed72c4b922dd505ec 244 PIRSF PIRSF009120 1 244 1.1E-102 T 14-10-2018 IPR016545 Uncharacterised conserved protein UCP009120, proteasome-type protease, Sll0069 TSH58p_03045 c87651e06b45ffaed72c4b922dd505ec 244 Gene3D G3DSA:3.60.20.10 2 237 3.8E-23 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_03045 c87651e06b45ffaed72c4b922dd505ec 244 SUPERFAMILY SSF56235 2 241 2.42E-32 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_29685 df7ad5e2342395edf5575496e314ce16 250 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 6 240 1.6E-85 T 14-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 TSH58p_29685 df7ad5e2342395edf5575496e314ce16 250 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 6 239 9.4E-100 T 14-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 TSH58p_29685 df7ad5e2342395edf5575496e314ce16 250 Gene3D G3DSA:3.20.20.70 1 249 6.5E-102 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_29685 df7ad5e2342395edf5575496e314ce16 250 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 244 123.367 T 14-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 TSH58p_29685 df7ad5e2342395edf5575496e314ce16 250 SUPERFAMILY SSF63892 5 243 2.88E-96 T 14-10-2018 IPR036130 Pyridoxine 5'-phosphate synthase GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 TSH58p_05410 46a2e2a57f51a16456828b9efa75ec03 339 Gene3D G3DSA:3.40.190.10 112 221 1.5E-115 T 14-10-2018 TSH58p_05410 46a2e2a57f51a16456828b9efa75ec03 339 Gene3D G3DSA:3.40.190.10 33 330 1.5E-115 T 14-10-2018 TSH58p_05410 46a2e2a57f51a16456828b9efa75ec03 339 SUPERFAMILY SSF53850 29 277 1.41E-48 T 14-10-2018 TSH58p_05410 46a2e2a57f51a16456828b9efa75ec03 339 Pfam PF09084 NMT1/THI5 like 44 254 4.3E-31 T 14-10-2018 IPR015168 SsuA/THI5-like TSH58p_27365 0e3b32a9b6c7d78972ef270d2d698908 325 SUPERFAMILY SSF53474 112 272 1.79E-16 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_27365 0e3b32a9b6c7d78972ef270d2d698908 325 Gene3D G3DSA:3.40.50.1820 65 283 1.7E-11 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_10800 6065c07004f8c4eb0a7c6836eff124f0 501 Pfam PF00561 alpha/beta hydrolase fold 85 464 6.2E-23 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_10800 6065c07004f8c4eb0a7c6836eff124f0 501 SUPERFAMILY SSF53474 79 467 3.18E-28 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_06085 484ea52a6901d923e6e5f17b7281a147 344 Gene3D G3DSA:3.40.50.2300 37 178 6.6E-32 T 14-10-2018 TSH58p_06085 484ea52a6901d923e6e5f17b7281a147 344 Pfam PF00072 Response regulator receiver domain 53 164 1.2E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_06085 484ea52a6901d923e6e5f17b7281a147 344 SMART SM00267 170 343 9.3E-68 T 14-10-2018 IPR000160 GGDEF domain TSH58p_06085 484ea52a6901d923e6e5f17b7281a147 344 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 177 341 3.3E-49 T 14-10-2018 IPR000160 GGDEF domain TSH58p_06085 484ea52a6901d923e6e5f17b7281a147 344 SMART SM00448 51 164 1.2E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_06085 484ea52a6901d923e6e5f17b7281a147 344 SUPERFAMILY SSF52172 45 176 1.05E-34 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_06085 484ea52a6901d923e6e5f17b7281a147 344 SUPERFAMILY SSF55073 186 341 2.43E-49 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_06085 484ea52a6901d923e6e5f17b7281a147 344 Gene3D G3DSA:3.30.70.270 179 342 4.5E-58 T 14-10-2018 TSH58p_06085 484ea52a6901d923e6e5f17b7281a147 344 Pfam PF00990 Diguanylate cyclase, GGDEF domain 181 339 2.4E-46 T 14-10-2018 IPR000160 GGDEF domain TSH58p_07650 029da1c337714c7ad67f7197fa18e0af 176 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 4 140 7.1E-31 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type TSH58p_07650 029da1c337714c7ad67f7197fa18e0af 176 Pfam PF02082 Transcriptional regulator 4 83 6.5E-25 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type TSH58p_07650 029da1c337714c7ad67f7197fa18e0af 176 SUPERFAMILY SSF46785 8 140 1.5E-32 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_07650 029da1c337714c7ad67f7197fa18e0af 176 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 14-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site TSH58p_07650 029da1c337714c7ad67f7197fa18e0af 176 Gene3D G3DSA:1.10.10.10 2 147 9.0E-33 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_26910 c7757f81fdf4281781328d61584b3f8c 243 SUPERFAMILY SSF51735 13 243 8.47E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_26910 c7757f81fdf4281781328d61584b3f8c 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 3.2E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_26910 c7757f81fdf4281781328d61584b3f8c 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 3.2E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_26910 c7757f81fdf4281781328d61584b3f8c 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 3.2E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_26910 c7757f81fdf4281781328d61584b3f8c 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 3.2E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_26910 c7757f81fdf4281781328d61584b3f8c 243 Gene3D G3DSA:3.40.50.720 10 243 1.9E-40 T 14-10-2018 TSH58p_26910 c7757f81fdf4281781328d61584b3f8c 243 Pfam PF00106 short chain dehydrogenase 13 200 8.4E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_09510 9042644a14c671e6395bcbdccdce6961 327 Pfam PF00535 Glycosyl transferase family 2 18 170 8.6E-15 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_09510 9042644a14c671e6395bcbdccdce6961 327 Gene3D G3DSA:3.90.550.10 3 240 3.2E-41 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_09510 9042644a14c671e6395bcbdccdce6961 327 SUPERFAMILY SSF53448 3 245 5.34E-32 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_12510 7b67e508cdc8b824dfd02fa5ef4eceb9 255 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 31 243 2.9E-43 T 14-10-2018 IPR039447 Urease accessory protein UreH-like, transmembrane domain TSH58p_09700 b3cc55dd6f9c3aac5636ec8d3d57a319 141 Gene3D G3DSA:3.30.1490.190 71 120 1.9E-18 T 14-10-2018 TSH58p_09700 b3cc55dd6f9c3aac5636ec8d3d57a319 141 Gene3D G3DSA:1.10.10.10 1 69 5.7E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_09700 b3cc55dd6f9c3aac5636ec8d3d57a319 141 SUPERFAMILY SSF46785 1 117 1.14E-32 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_09700 b3cc55dd6f9c3aac5636ec8d3d57a319 141 Pfam PF01475 Ferric uptake regulator family 1 115 1.2E-34 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 TSH58p_07270 784231a33357401905d0fb9f27fd7f4a 222 Pfam PF05063 MT-A70 29 212 2.7E-25 T 14-10-2018 IPR007757 MT-A70-like TSH58p_12985 8e687ab452f8b6b49e4d5bf816284275 658 SUPERFAMILY SSF51126 15 643 1.18E-35 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor TSH58p_12985 8e687ab452f8b6b49e4d5bf816284275 658 SMART SM00710 460 497 5000.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_12985 8e687ab452f8b6b49e4d5bf816284275 658 SMART SM00710 325 346 1000.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_12985 8e687ab452f8b6b49e4d5bf816284275 658 SMART SM00710 347 369 700.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_12985 8e687ab452f8b6b49e4d5bf816284275 658 SMART SM00710 428 455 2000.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_12985 8e687ab452f8b6b49e4d5bf816284275 658 SMART SM00710 581 602 6200.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_12985 8e687ab452f8b6b49e4d5bf816284275 658 SMART SM00710 371 398 2000.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_12985 8e687ab452f8b6b49e4d5bf816284275 658 SMART SM00710 499 521 2400.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_12985 8e687ab452f8b6b49e4d5bf816284275 658 SMART SM00710 399 421 15.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_12985 8e687ab452f8b6b49e4d5bf816284275 658 Gene3D G3DSA:2.160.20.10 270 615 3.6E-24 T 14-10-2018 IPR012334 Pectin lyase fold TSH58p_12985 8e687ab452f8b6b49e4d5bf816284275 658 Pfam PF13229 Right handed beta helix region 323 531 1.5E-13 T 14-10-2018 IPR039448 Right handed beta helix domain TSH58p_12985 8e687ab452f8b6b49e4d5bf816284275 658 Gene3D G3DSA:2.160.20.10 23 143 6.5E-11 T 14-10-2018 IPR012334 Pectin lyase fold TSH58p_10500 275e3e491bff4be024595b579d6decac 177 SUPERFAMILY SSF47240 15 163 4.17E-31 T 14-10-2018 IPR009078 Ferritin-like superfamily TSH58p_10500 275e3e491bff4be024595b579d6decac 177 Pfam PF02915 Rubrerythrin 15 91 2.1E-9 T 14-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TSH58p_10500 275e3e491bff4be024595b579d6decac 177 Pfam PF02915 Rubrerythrin 107 160 9.6E-8 T 14-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TSH58p_10500 275e3e491bff4be024595b579d6decac 177 Gene3D G3DSA:1.20.1260.10 9 160 3.4E-51 T 14-10-2018 IPR012347 Ferritin-like TSH58p_23560 e79bdcaaa2fd8a8d1ce531be484f426a 666 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 622 639 - T 14-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TSH58p_23560 e79bdcaaa2fd8a8d1ce531be484f426a 666 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TSH58p_23560 e79bdcaaa2fd8a8d1ce531be484f426a 666 SUPERFAMILY SSF51246 331 446 6.8E-43 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TSH58p_23560 e79bdcaaa2fd8a8d1ce531be484f426a 666 SMART SM00878 336 443 7.8E-62 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TSH58p_23560 e79bdcaaa2fd8a8d1ce531be484f426a 666 SUPERFAMILY SSF56059 83 348 8.84E-70 T 14-10-2018 TSH58p_23560 e79bdcaaa2fd8a8d1ce531be484f426a 666 Gene3D G3DSA:3.30.700.30 450 586 4.2E-30 T 14-10-2018 TSH58p_23560 e79bdcaaa2fd8a8d1ce531be484f426a 666 SUPERFAMILY SSF52440 2 113 3.74E-48 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TSH58p_23560 e79bdcaaa2fd8a8d1ce531be484f426a 666 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TSH58p_23560 e79bdcaaa2fd8a8d1ce531be484f426a 666 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 110 8.7E-44 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TSH58p_23560 e79bdcaaa2fd8a8d1ce531be484f426a 666 Pfam PF00364 Biotin-requiring enzyme 602 664 1.4E-15 T 14-10-2018 IPR000089 Biotin/lipoyl attachment TSH58p_23560 e79bdcaaa2fd8a8d1ce531be484f426a 666 Gene3D G3DSA:3.30.470.130 1 448 7.7E-206 T 14-10-2018 TSH58p_23560 e79bdcaaa2fd8a8d1ce531be484f426a 666 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 2 444 5.0E-189 T 14-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 TSH58p_23560 e79bdcaaa2fd8a8d1ce531be484f426a 666 SUPERFAMILY SSF51230 587 665 5.23E-19 T 14-10-2018 IPR011053 Single hybrid motif TSH58p_23560 e79bdcaaa2fd8a8d1ce531be484f426a 666 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 7.4E-82 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TSH58p_23560 e79bdcaaa2fd8a8d1ce531be484f426a 666 Pfam PF02785 Biotin carboxylase C-terminal domain 336 443 1.1E-39 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TSH58p_23560 e79bdcaaa2fd8a8d1ce531be484f426a 666 Gene3D G3DSA:2.40.50.100 599 665 4.8E-21 T 14-10-2018 TSH58p_04240 f884e40045d897c27eee95dd1af3094c 274 SUPERFAMILY SSF52402 1 143 2.85E-12 T 14-10-2018 TSH58p_04240 f884e40045d897c27eee95dd1af3094c 274 Gene3D G3DSA:3.40.50.12370 6 273 8.9E-31 T 14-10-2018 TSH58p_04240 f884e40045d897c27eee95dd1af3094c 274 Pfam PF00582 Universal stress protein family 3 143 2.1E-5 T 14-10-2018 IPR006016 UspA TSH58p_04240 f884e40045d897c27eee95dd1af3094c 274 Pfam PF00582 Universal stress protein family 218 272 9.6E-8 T 14-10-2018 IPR006016 UspA TSH58p_04240 f884e40045d897c27eee95dd1af3094c 274 PRINTS PR01438 Universal stress protein signature 234 246 1.8E-5 T 14-10-2018 IPR006015 Universal stress protein A TSH58p_04240 f884e40045d897c27eee95dd1af3094c 274 PRINTS PR01438 Universal stress protein signature 252 274 1.8E-5 T 14-10-2018 IPR006015 Universal stress protein A TSH58p_04240 f884e40045d897c27eee95dd1af3094c 274 SUPERFAMILY SSF52402 154 273 4.52E-18 T 14-10-2018 TSH58p_21135 fc3583ae21b8c3a075b2ad5ab60bb439 553 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 88 459 4.2E-89 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain TSH58p_21135 fc3583ae21b8c3a075b2ad5ab60bb439 553 Gene3D G3DSA:3.10.105.10 306 532 2.5E-127 T 14-10-2018 TSH58p_21135 fc3583ae21b8c3a075b2ad5ab60bb439 553 PIRSF PIRSF002741 19 549 9.3E-95 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TSH58p_21135 fc3583ae21b8c3a075b2ad5ab60bb439 553 Gene3D G3DSA:3.40.190.10 52 305 2.5E-127 T 14-10-2018 TSH58p_21135 fc3583ae21b8c3a075b2ad5ab60bb439 553 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 93 114 - T 14-10-2018 IPR023765 Solute-binding protein family 5, conserved site TSH58p_21135 fc3583ae21b8c3a075b2ad5ab60bb439 553 Gene3D G3DSA:3.90.76.10 78 196 2.5E-127 T 14-10-2018 TSH58p_21135 fc3583ae21b8c3a075b2ad5ab60bb439 553 SUPERFAMILY SSF53850 41 535 8.69E-126 T 14-10-2018 TSH58p_15455 c789ae4be60cc228363844e6afe5a8bb 1157 SUPERFAMILY SSF48452 618 687 7.91E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_15455 c789ae4be60cc228363844e6afe5a8bb 1157 Gene3D G3DSA:1.25.40.10 695 900 5.7E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_15455 c789ae4be60cc228363844e6afe5a8bb 1157 SUPERFAMILY SSF48452 694 820 3.8E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_19190 e72dd72999109b2e1d935908504ade2f 139 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 16 36 - T 14-10-2018 IPR019776 Flagellar basal body rod protein, conserved site TSH58p_19190 e72dd72999109b2e1d935908504ade2f 139 Pfam PF00460 Flagella basal body rod protein 10 37 2.9E-7 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 TSH58p_19190 e72dd72999109b2e1d935908504ade2f 139 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 9 138 5.0E-45 T 14-10-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 TSH58p_19190 e72dd72999109b2e1d935908504ade2f 139 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 91 136 1.5E-9 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain TSH58p_30635 03384cc149eedd6c1b8f62742622e9b6 775 Gene3D G3DSA:2.40.40.20 597 757 1.1E-47 T 14-10-2018 TSH58p_30635 03384cc149eedd6c1b8f62742622e9b6 775 Pfam PF00384 Molybdopterin oxidoreductase 47 507 1.4E-66 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_30635 03384cc149eedd6c1b8f62742622e9b6 775 Pfam PF01568 Molydopterin dinucleotide binding domain 620 739 6.9E-24 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TSH58p_30635 03384cc149eedd6c1b8f62742622e9b6 775 Gene3D G3DSA:3.40.228.10 143 588 2.7E-190 T 14-10-2018 TSH58p_30635 03384cc149eedd6c1b8f62742622e9b6 775 Gene3D G3DSA:3.90.55.10 4 556 2.7E-190 T 14-10-2018 TSH58p_30635 03384cc149eedd6c1b8f62742622e9b6 775 SUPERFAMILY SSF53706 5 608 2.66E-150 T 14-10-2018 TSH58p_30635 03384cc149eedd6c1b8f62742622e9b6 775 SUPERFAMILY SSF50692 613 761 1.2E-42 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TSH58p_30635 03384cc149eedd6c1b8f62742622e9b6 775 Gene3D G3DSA:3.40.50.740 47 515 2.7E-190 T 14-10-2018 TSH58p_30635 03384cc149eedd6c1b8f62742622e9b6 775 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 659 686 - T 14-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 TSH58p_10900 ffc1070271ef34420a309711dac7788d 395 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 206 393 4.1E-28 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_10900 ffc1070271ef34420a309711dac7788d 395 SUPERFAMILY SSF161098 183 380 4.06E-23 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_10900 ffc1070271ef34420a309711dac7788d 395 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 44 96 8.0E-11 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TSH58p_10900 ffc1070271ef34420a309711dac7788d 395 Gene3D G3DSA:1.10.3720.10 178 390 1.9E-19 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_02550 2defbeaa22283e98ab9f84fde3b39350 258 PIRSF PIRSF000709 3 200 6.5E-19 T 14-10-2018 TSH58p_02550 2defbeaa22283e98ab9f84fde3b39350 258 SMART SM00855 8 184 8.2E-18 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TSH58p_02550 2defbeaa22283e98ab9f84fde3b39350 258 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 11 20 - T 14-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 TSH58p_02550 2defbeaa22283e98ab9f84fde3b39350 258 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 9 222 4.9E-35 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TSH58p_02550 2defbeaa22283e98ab9f84fde3b39350 258 Gene3D G3DSA:3.40.50.1240 1 232 4.1E-46 T 14-10-2018 IPR029033 Histidine phosphatase superfamily TSH58p_02550 2defbeaa22283e98ab9f84fde3b39350 258 SUPERFAMILY SSF53254 7 238 6.13E-46 T 14-10-2018 IPR029033 Histidine phosphatase superfamily TSH58p_09370 50aa5e85713ac2c983ba6a17c73a6cce 563 SMART SM00304 214 267 3.0E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_09370 50aa5e85713ac2c983ba6a17c73a6cce 563 SUPERFAMILY SSF58104 243 556 1.28E-64 T 14-10-2018 TSH58p_09370 50aa5e85713ac2c983ba6a17c73a6cce 563 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 365 528 1.9E-30 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_09370 50aa5e85713ac2c983ba6a17c73a6cce 563 Pfam PF12729 Four helix bundle sensory module for signal transduction 7 187 4.3E-25 T 14-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain TSH58p_09370 50aa5e85713ac2c983ba6a17c73a6cce 563 Gene3D G3DSA:1.10.287.950 269 557 1.6E-54 T 14-10-2018 TSH58p_09370 50aa5e85713ac2c983ba6a17c73a6cce 563 SMART SM00283 303 557 6.0E-46 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_09370 50aa5e85713ac2c983ba6a17c73a6cce 563 Gene3D G3DSA:1.10.8.500 214 265 3.0E-14 T 14-10-2018 TSH58p_00430 d5e2660a00809cf76ccafb59cfea95a1 427 Gene3D G3DSA:3.40.50.2300 152 388 1.6E-89 T 14-10-2018 TSH58p_00430 d5e2660a00809cf76ccafb59cfea95a1 427 Gene3D G3DSA:3.40.50.2300 27 382 1.6E-89 T 14-10-2018 TSH58p_00430 d5e2660a00809cf76ccafb59cfea95a1 427 Pfam PF13458 Periplasmic binding protein 26 393 6.5E-59 T 14-10-2018 IPR028081 Leucine-binding protein domain TSH58p_00430 d5e2660a00809cf76ccafb59cfea95a1 427 SUPERFAMILY SSF53822 25 390 2.2E-49 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_01620 ad1804633e35365499465ee16e080858 499 Pfam PF12697 Alpha/beta hydrolase family 122 258 1.5E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_01620 ad1804633e35365499465ee16e080858 499 Gene3D G3DSA:3.40.50.1820 107 361 2.5E-30 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_01620 ad1804633e35365499465ee16e080858 499 SUPERFAMILY SSF53474 79 339 7.7E-25 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_01590 7d678d8d676e18b3db49112c7752b798 842 SMART SM00965 89 140 4.6E-11 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 TSH58p_01590 7d678d8d676e18b3db49112c7752b798 842 Gene3D G3DSA:2.170.130.10 184 305 4.7E-19 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily TSH58p_01590 7d678d8d676e18b3db49112c7752b798 842 Gene3D G3DSA:2.40.170.20 306 842 2.6E-79 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily TSH58p_01590 7d678d8d676e18b3db49112c7752b798 842 Gene3D G3DSA:3.55.50.30 59 160 2.7E-31 T 14-10-2018 TSH58p_01590 7d678d8d676e18b3db49112c7752b798 842 Pfam PF07715 TonB-dependent Receptor Plug Domain 192 285 8.5E-12 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain TSH58p_01590 7d678d8d676e18b3db49112c7752b798 842 Pfam PF00593 TonB dependent receptor 440 839 1.1E-36 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel TSH58p_01590 7d678d8d676e18b3db49112c7752b798 842 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 825 842 - T 14-10-2018 IPR010917 TonB-dependent receptor, conserved site TSH58p_01590 7d678d8d676e18b3db49112c7752b798 842 SUPERFAMILY SSF56935 142 842 8.85E-103 T 14-10-2018 TSH58p_01590 7d678d8d676e18b3db49112c7752b798 842 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 194 842 2.4E-103 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 TSH58p_01590 7d678d8d676e18b3db49112c7752b798 842 Pfam PF07660 Secretin and TonB N terminus short domain 89 139 5.9E-7 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 TSH58p_15590 b7029cf623eb7d747b5735f4460cf1c6 159 Pfam PF06146 Phosphate-starvation-inducible E 69 114 5.3E-8 T 14-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like TSH58p_20310 26787ac033e100c26e1fde4901bdad1d 225 Gene3D G3DSA:1.10.150.240 23 84 8.8E-31 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 TSH58p_20310 26787ac033e100c26e1fde4901bdad1d 225 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 80 182 8.0E-9 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_20310 26787ac033e100c26e1fde4901bdad1d 225 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 88 188 2.6E-9 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_20310 26787ac033e100c26e1fde4901bdad1d 225 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 187 4.8E-29 T 14-10-2018 TSH58p_20310 26787ac033e100c26e1fde4901bdad1d 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 5 16 2.9E-6 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_20310 26787ac033e100c26e1fde4901bdad1d 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 133 149 2.9E-6 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_20310 26787ac033e100c26e1fde4901bdad1d 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 102 115 2.9E-6 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_20310 26787ac033e100c26e1fde4901bdad1d 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 151 171 2.9E-6 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_20310 26787ac033e100c26e1fde4901bdad1d 225 SUPERFAMILY SSF56784 6 219 1.63E-56 T 14-10-2018 IPR036412 HAD-like superfamily TSH58p_24645 622b7e5f70ddea9f5124e07c39c2b4c0 121 PIRSF PIRSF007028 1 121 3.5E-46 T 14-10-2018 IPR009874 Protein of unknown function DUF1428 TSH58p_24645 622b7e5f70ddea9f5124e07c39c2b4c0 121 SUPERFAMILY SSF54909 1 120 4.18E-46 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel TSH58p_24645 622b7e5f70ddea9f5124e07c39c2b4c0 121 Gene3D G3DSA:3.30.70.100 1 121 4.0E-42 T 14-10-2018 TSH58p_24645 622b7e5f70ddea9f5124e07c39c2b4c0 121 Pfam PF07237 Protein of unknown function (DUF1428) 3 107 7.1E-42 T 14-10-2018 IPR009874 Protein of unknown function DUF1428 TSH58p_07445 44144b66846f37b5718f469bd92dabc2 479 SUPERFAMILY SSF55103 232 479 6.87E-58 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 TSH58p_07445 44144b66846f37b5718f469bd92dabc2 479 Gene3D G3DSA:3.30.70.2190 227 350 9.9E-38 T 14-10-2018 TSH58p_07445 44144b66846f37b5718f469bd92dabc2 479 Pfam PF01565 FAD binding domain 51 187 1.3E-39 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TSH58p_07445 44144b66846f37b5718f469bd92dabc2 479 Gene3D G3DSA:3.30.43.10 7 103 9.8E-30 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 TSH58p_07445 44144b66846f37b5718f469bd92dabc2 479 Gene3D G3DSA:1.10.45.10 438 478 4.6E-13 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 TSH58p_07445 44144b66846f37b5718f469bd92dabc2 479 Gene3D G3DSA:3.30.465.10 105 226 2.3E-45 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TSH58p_07445 44144b66846f37b5718f469bd92dabc2 479 Gene3D G3DSA:3.30.70.2740 351 437 1.0E-28 T 14-10-2018 TSH58p_07445 44144b66846f37b5718f469bd92dabc2 479 Pfam PF02913 FAD linked oxidases, C-terminal domain 227 476 2.9E-56 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 TSH58p_07445 44144b66846f37b5718f469bd92dabc2 479 SUPERFAMILY SSF56176 13 227 1.59E-76 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TSH58p_30720 e7c4c19dd98804901dcc675b06053bd0 315 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_30720 e7c4c19dd98804901dcc675b06053bd0 315 SUPERFAMILY SSF52540 8 251 1.91E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_30720 e7c4c19dd98804901dcc675b06053bd0 315 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 231 293 1.6E-18 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_30720 e7c4c19dd98804901dcc675b06053bd0 315 SMART SM00382 37 237 4.6E-19 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_30720 e7c4c19dd98804901dcc675b06053bd0 315 Pfam PF00005 ABC transporter 29 179 4.4E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_30720 e7c4c19dd98804901dcc675b06053bd0 315 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 229 312 2.5E-20 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_30720 e7c4c19dd98804901dcc675b06053bd0 315 Gene3D G3DSA:3.40.50.300 7 315 2.1E-95 T 14-10-2018 TSH58p_03020 56b45c8d7d03ca6f987c60fa5eab6a1b 260 Gene3D G3DSA:3.40.50.300 3 242 1.6E-61 T 14-10-2018 TSH58p_03020 56b45c8d7d03ca6f987c60fa5eab6a1b 260 SUPERFAMILY SSF52540 4 242 8.72E-72 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_03020 56b45c8d7d03ca6f987c60fa5eab6a1b 260 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_03020 56b45c8d7d03ca6f987c60fa5eab6a1b 260 SMART SM00382 34 227 1.9E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_03020 56b45c8d7d03ca6f987c60fa5eab6a1b 260 Pfam PF00005 ABC transporter 26 165 1.0E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_09960 7793099dae113ca93c1e93ef1e8ce331 357 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 320 1.6E-125 T 14-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 TSH58p_09960 7793099dae113ca93c1e93ef1e8ce331 357 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 1.1E-44 T 14-10-2018 IPR017861 Kae1/TsaD family TSH58p_09960 7793099dae113ca93c1e93ef1e8ce331 357 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 1.1E-44 T 14-10-2018 IPR017861 Kae1/TsaD family TSH58p_09960 7793099dae113ca93c1e93ef1e8ce331 357 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 270 279 1.1E-44 T 14-10-2018 IPR017861 Kae1/TsaD family TSH58p_09960 7793099dae113ca93c1e93ef1e8ce331 357 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 1.1E-44 T 14-10-2018 IPR017861 Kae1/TsaD family TSH58p_09960 7793099dae113ca93c1e93ef1e8ce331 357 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 130 142 1.1E-44 T 14-10-2018 IPR017861 Kae1/TsaD family TSH58p_09960 7793099dae113ca93c1e93ef1e8ce331 357 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 153 174 1.1E-44 T 14-10-2018 IPR017861 Kae1/TsaD family TSH58p_09960 7793099dae113ca93c1e93ef1e8ce331 357 Gene3D G3DSA:3.30.420.40 128 300 3.6E-120 T 14-10-2018 TSH58p_09960 7793099dae113ca93c1e93ef1e8ce331 357 Gene3D G3DSA:3.30.420.40 3 321 3.6E-120 T 14-10-2018 TSH58p_09960 7793099dae113ca93c1e93ef1e8ce331 357 Pfam PF00814 Glycoprotease family 23 314 8.4E-97 T 14-10-2018 IPR000905 Gcp-like domain TSH58p_09960 7793099dae113ca93c1e93ef1e8ce331 357 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 313 3.6E-97 T 14-10-2018 IPR017861 Kae1/TsaD family TSH58p_09960 7793099dae113ca93c1e93ef1e8ce331 357 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 338 64.87 T 14-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 TSH58p_09960 7793099dae113ca93c1e93ef1e8ce331 357 SUPERFAMILY SSF53067 1 318 5.47E-42 T 14-10-2018 TSH58p_20990 11e6e309b45509c12421fdec9df31dc9 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 129 306 2.0E-26 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_20990 11e6e309b45509c12421fdec9df31dc9 312 SUPERFAMILY SSF161098 107 289 5.07E-19 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_20990 11e6e309b45509c12421fdec9df31dc9 312 Gene3D G3DSA:1.10.3720.10 101 298 3.6E-21 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_26010 0283bbd6e36c1c32f2ab5395f030ef8d 304 Pfam PF09361 Phasin protein 30 116 2.1E-6 T 14-10-2018 IPR018968 Phasin TSH58p_26010 0283bbd6e36c1c32f2ab5395f030ef8d 304 PRINTS PR00624 Histone H5 signature 146 160 8.2E-6 T 14-10-2018 IPR005819 Histone H5 GO:0000786|GO:0003677|GO:0006334 TSH58p_26010 0283bbd6e36c1c32f2ab5395f030ef8d 304 PRINTS PR00624 Histone H5 signature 179 196 8.2E-6 T 14-10-2018 IPR005819 Histone H5 GO:0000786|GO:0003677|GO:0006334 TSH58p_26010 0283bbd6e36c1c32f2ab5395f030ef8d 304 PRINTS PR00624 Histone H5 signature 201 220 8.2E-6 T 14-10-2018 IPR005819 Histone H5 GO:0000786|GO:0003677|GO:0006334 TSH58p_14215 9ec74ac1b83a7ada4315056b52fb9641 153 Gene3D G3DSA:1.10.3680.10 1 137 1.4E-18 T 14-10-2018 IPR029024 TerB-like TSH58p_14215 9ec74ac1b83a7ada4315056b52fb9641 153 SUPERFAMILY SSF158682 19 146 7.72E-26 T 14-10-2018 IPR029024 TerB-like TSH58p_14215 9ec74ac1b83a7ada4315056b52fb9641 153 Pfam PF05099 Tellurite resistance protein TerB 8 138 7.0E-32 T 14-10-2018 IPR007791 Co-chaperone DjlA, N-terminal TSH58p_14710 b904554486fe5d3141d48826b5a8d13c 285 SUPERFAMILY SSF56300 10 249 1.9E-35 T 14-10-2018 TSH58p_14710 b904554486fe5d3141d48826b5a8d13c 285 Gene3D G3DSA:3.60.21.10 11 243 1.1E-19 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like TSH58p_14710 b904554486fe5d3141d48826b5a8d13c 285 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 13 225 8.9E-14 T 14-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 TSH58p_08130 937c435b7b549ebdce2707687bae1193 273 PIRSF PIRSF000126 2 256 7.7E-55 T 14-10-2018 TSH58p_08130 937c435b7b549ebdce2707687bae1193 273 Pfam PF00106 short chain dehydrogenase 5 193 5.8E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_08130 937c435b7b549ebdce2707687bae1193 273 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 188 4.1E-4 T 14-10-2018 TSH58p_08130 937c435b7b549ebdce2707687bae1193 273 Gene3D G3DSA:3.40.50.720 2 240 3.0E-49 T 14-10-2018 TSH58p_08130 937c435b7b549ebdce2707687bae1193 273 SUPERFAMILY SSF51735 4 228 2.79E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_08130 937c435b7b549ebdce2707687bae1193 273 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_08130 937c435b7b549ebdce2707687bae1193 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 5.4E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_08130 937c435b7b549ebdce2707687bae1193 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 5.4E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_08130 937c435b7b549ebdce2707687bae1193 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 4.4E-16 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_08130 937c435b7b549ebdce2707687bae1193 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 4.4E-16 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_08130 937c435b7b549ebdce2707687bae1193 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 4.4E-16 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_08130 937c435b7b549ebdce2707687bae1193 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.4E-16 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_08130 937c435b7b549ebdce2707687bae1193 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.4E-16 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_12215 a56c08861d35402c4916fe83e838ca0a 107 SUPERFAMILY SSF52833 2 107 5.2E-41 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_12215 a56c08861d35402c4916fe83e838ca0a 107 PRINTS PR00421 Thioredoxin family signature 23 31 2.3E-10 T 14-10-2018 TSH58p_12215 a56c08861d35402c4916fe83e838ca0a 107 PRINTS PR00421 Thioredoxin family signature 31 40 2.3E-10 T 14-10-2018 TSH58p_12215 a56c08861d35402c4916fe83e838ca0a 107 PRINTS PR00421 Thioredoxin family signature 71 82 2.3E-10 T 14-10-2018 TSH58p_12215 a56c08861d35402c4916fe83e838ca0a 107 Pfam PF00085 Thioredoxin 5 105 1.4E-34 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 TSH58p_12215 a56c08861d35402c4916fe83e838ca0a 107 ProSitePatterns PS00194 Thioredoxin family active site. 24 42 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 TSH58p_12215 a56c08861d35402c4916fe83e838ca0a 107 TIGRFAM TIGR01068 thioredoxin: thioredoxin 8 105 2.8E-39 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 TSH58p_12215 a56c08861d35402c4916fe83e838ca0a 107 PIRSF PIRSF000077 1 107 3.1E-44 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 TSH58p_12215 a56c08861d35402c4916fe83e838ca0a 107 Gene3D G3DSA:3.40.30.10 1 107 6.3E-37 T 14-10-2018 TSH58p_02605 148e9a3c044c7bc37b161c62a62fdc78 177 SUPERFAMILY SSF46689 119 173 1.14E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_02605 148e9a3c044c7bc37b161c62a62fdc78 177 Gene3D G3DSA:1.10.10.60 120 175 1.5E-19 T 14-10-2018 TSH58p_02605 148e9a3c044c7bc37b161c62a62fdc78 177 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 157 177 1.0E-7 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_02605 148e9a3c044c7bc37b161c62a62fdc78 177 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 140 157 1.0E-7 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_02605 148e9a3c044c7bc37b161c62a62fdc78 177 Pfam PF02954 Bacterial regulatory protein, Fis family 134 173 1.7E-12 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_02605 148e9a3c044c7bc37b161c62a62fdc78 177 SMART SM00448 5 116 1.2E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_02605 148e9a3c044c7bc37b161c62a62fdc78 177 SUPERFAMILY SSF52172 5 120 2.56E-27 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_02605 148e9a3c044c7bc37b161c62a62fdc78 177 Pfam PF00072 Response regulator receiver domain 8 116 2.4E-19 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_02605 148e9a3c044c7bc37b161c62a62fdc78 177 Gene3D G3DSA:3.40.50.2300 2 119 2.9E-25 T 14-10-2018 TSH58p_00195 3b221857a4839447e93949d060c7ff2a 548 Gene3D G3DSA:3.30.470.20 286 444 2.4E-11 T 14-10-2018 TSH58p_00195 3b221857a4839447e93949d060c7ff2a 548 SUPERFAMILY SSF56059 295 540 6.43E-29 T 14-10-2018 TSH58p_00195 3b221857a4839447e93949d060c7ff2a 548 SUPERFAMILY SSF55729 25 216 7.38E-22 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_00195 3b221857a4839447e93949d060c7ff2a 548 Pfam PF08443 RimK-like ATP-grasp domain 294 396 6.6E-7 T 14-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 TSH58p_00195 3b221857a4839447e93949d060c7ff2a 548 Gene3D G3DSA:3.40.630.30 24 222 5.2E-19 T 14-10-2018 TSH58p_00195 3b221857a4839447e93949d060c7ff2a 548 Pfam PF00583 Acetyltransferase (GNAT) family 111 210 1.7E-9 T 14-10-2018 IPR000182 GNAT domain TSH58p_00195 3b221857a4839447e93949d060c7ff2a 548 Gene3D G3DSA:3.30.470.20 451 539 1.9E-9 T 14-10-2018 TSH58p_00195 3b221857a4839447e93949d060c7ff2a 548 TIGRFAM TIGR03103 trio_acet_GNAT: GNAT-family acetyltransferase TIGR03103 4 542 3.9E-267 T 14-10-2018 IPR017534 GNAT-acetyltransferase TSH58p_31090 851a08b7ae0a43e5ff32200939cb7aca 797 Gene3D G3DSA:3.55.50.30 21 122 3.0E-24 T 14-10-2018 TSH58p_31090 851a08b7ae0a43e5ff32200939cb7aca 797 Pfam PF07715 TonB-dependent Receptor Plug Domain 150 245 1.3E-14 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain TSH58p_31090 851a08b7ae0a43e5ff32200939cb7aca 797 Gene3D G3DSA:2.170.130.10 143 263 2.2E-22 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily TSH58p_31090 851a08b7ae0a43e5ff32200939cb7aca 797 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 152 797 2.3E-105 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 TSH58p_31090 851a08b7ae0a43e5ff32200939cb7aca 797 Gene3D G3DSA:2.40.170.20 264 797 3.6E-82 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily TSH58p_31090 851a08b7ae0a43e5ff32200939cb7aca 797 Pfam PF00593 TonB dependent receptor 338 795 6.9E-36 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel TSH58p_31090 851a08b7ae0a43e5ff32200939cb7aca 797 SMART SM00965 51 102 1.5E-11 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 TSH58p_31090 851a08b7ae0a43e5ff32200939cb7aca 797 SUPERFAMILY SSF56935 103 797 1.28E-100 T 14-10-2018 TSH58p_28440 96114e4a66de07c27ebf874ff36a9401 264 SMART SM00267 70 247 3.1E-36 T 14-10-2018 IPR000160 GGDEF domain TSH58p_28440 96114e4a66de07c27ebf874ff36a9401 264 Gene3D G3DSA:3.30.70.270 76 248 1.7E-45 T 14-10-2018 TSH58p_28440 96114e4a66de07c27ebf874ff36a9401 264 SUPERFAMILY SSF55073 86 243 7.85E-38 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_28440 96114e4a66de07c27ebf874ff36a9401 264 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 77 243 2.3E-37 T 14-10-2018 IPR000160 GGDEF domain TSH58p_28440 96114e4a66de07c27ebf874ff36a9401 264 Pfam PF00990 Diguanylate cyclase, GGDEF domain 82 241 3.2E-34 T 14-10-2018 IPR000160 GGDEF domain TSH58p_01680 dd39fc9f09d56892a022dbf796dbd76f 314 Pfam PF01548 Transposase 8 144 1.6E-20 T 14-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 TSH58p_01680 dd39fc9f09d56892a022dbf796dbd76f 314 Pfam PF02371 Transposase IS116/IS110/IS902 family 191 274 6.1E-15 T 14-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 TSH58p_03830 6954d7d650785f04fbdee0f32ec88f59 94 Pfam PF07369 Protein of unknown function (DUF1488) 6 84 1.1E-10 T 14-10-2018 IPR009962 Protein of unknown function DUF1488 TSH58p_03830 6954d7d650785f04fbdee0f32ec88f59 94 SUPERFAMILY SSF160272 5 84 1.26E-5 T 14-10-2018 IPR036692 Shew3726-like superfamily TSH58p_06210 5192133d372ff1fb3866cf5c22a365bd 192 Pfam PF09335 SNARE associated Golgi protein 52 153 1.4E-10 T 14-10-2018 IPR032816 SNARE associated Golgi protein TSH58p_30910 b01fd87e00c7daea992823bbfba90860 333 Pfam PF09084 NMT1/THI5 like 34 234 1.2E-18 T 14-10-2018 IPR015168 SsuA/THI5-like TSH58p_30910 b01fd87e00c7daea992823bbfba90860 333 SUPERFAMILY SSF53850 26 233 5.14E-39 T 14-10-2018 TSH58p_30910 b01fd87e00c7daea992823bbfba90860 333 Gene3D G3DSA:3.40.190.10 104 201 9.3E-47 T 14-10-2018 TSH58p_30910 b01fd87e00c7daea992823bbfba90860 333 Gene3D G3DSA:3.40.190.10 28 278 9.3E-47 T 14-10-2018 TSH58p_30910 b01fd87e00c7daea992823bbfba90860 333 TIGRFAM TIGR01729 taurine_ABC_bnd: taurine ABC transporter, periplasmic binding protein 27 330 8.8E-99 T 14-10-2018 IPR010068 Taurine ABC transporter, substrate-binding protein TauA GO:0015734|GO:0042597 TSH58p_30910 b01fd87e00c7daea992823bbfba90860 333 Gene3D G3DSA:1.10.8.450 237 273 9.3E-47 T 14-10-2018 TSH58p_30910 b01fd87e00c7daea992823bbfba90860 333 SMART SM00062 26 250 1.1E-8 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_13440 49d31849c01a7ec46934ab4f501bb28a 146 Pfam PF01047 MarR family 26 85 2.2E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_13440 49d31849c01a7ec46934ab4f501bb28a 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 61 76 7.2E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_13440 49d31849c01a7ec46934ab4f501bb28a 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 44 60 7.2E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_13440 49d31849c01a7ec46934ab4f501bb28a 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 96 7.2E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_13440 49d31849c01a7ec46934ab4f501bb28a 146 Gene3D G3DSA:1.10.10.10 5 136 4.7E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_13440 49d31849c01a7ec46934ab4f501bb28a 146 SMART SM00347 19 123 4.5E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_13440 49d31849c01a7ec46934ab4f501bb28a 146 SUPERFAMILY SSF46785 23 111 1.67E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_12210 5093a9ebb6873d63677c731300f1be48 298 Gene3D G3DSA:3.40.190.10 163 263 2.1E-60 T 14-10-2018 TSH58p_12210 5093a9ebb6873d63677c731300f1be48 298 SUPERFAMILY SSF46785 2 85 2.61E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_12210 5093a9ebb6873d63677c731300f1be48 298 Gene3D G3DSA:1.10.10.10 7 93 7.3E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_12210 5093a9ebb6873d63677c731300f1be48 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 6.7E-22 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_12210 5093a9ebb6873d63677c731300f1be48 298 Pfam PF03466 LysR substrate binding domain 90 294 9.4E-42 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_12210 5093a9ebb6873d63677c731300f1be48 298 Gene3D G3DSA:3.40.190.10 103 290 2.1E-60 T 14-10-2018 TSH58p_12210 5093a9ebb6873d63677c731300f1be48 298 SUPERFAMILY SSF53850 92 296 9.59E-40 T 14-10-2018 TSH58p_12210 5093a9ebb6873d63677c731300f1be48 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 6.2E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_12210 5093a9ebb6873d63677c731300f1be48 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 6.2E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_12210 5093a9ebb6873d63677c731300f1be48 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 6.2E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_07670 784fee55ebda4ae21a11fa9fca75671f 466 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 22 428 4.9E-112 T 14-10-2018 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 TSH58p_07670 784fee55ebda4ae21a11fa9fca75671f 466 Gene3D G3DSA:3.40.50.1980 22 162 4.8E-117 T 14-10-2018 TSH58p_07670 784fee55ebda4ae21a11fa9fca75671f 466 Gene3D G3DSA:3.40.50.1980 13 411 4.8E-117 T 14-10-2018 TSH58p_07670 784fee55ebda4ae21a11fa9fca75671f 466 Gene3D G3DSA:3.40.50.1980 163 418 4.8E-117 T 14-10-2018 TSH58p_07670 784fee55ebda4ae21a11fa9fca75671f 466 SUPERFAMILY SSF53807 11 435 9.16E-123 T 14-10-2018 TSH58p_07670 784fee55ebda4ae21a11fa9fca75671f 466 TIGRFAM TIGR01285 nifN: nitrogenase molybdenum-iron cofactor biosynthesis protein NifN 9 429 5.9E-170 T 14-10-2018 IPR005975 Nitrogenase molybdenum-iron cofactor biosynthesis protein GO:0009399|GO:0065003 TSH58p_07670 784fee55ebda4ae21a11fa9fca75671f 466 Gene3D G3DSA:1.20.89.10 269 432 4.8E-117 T 14-10-2018 TSH58p_07670 784fee55ebda4ae21a11fa9fca75671f 466 ProSitePatterns PS00699 Nitrogenases component 1 alpha and beta subunits signature 1. 40 47 - T 14-10-2018 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 TSH58p_08055 38df39e3b1c4fa79a10c924afae7ca3f 63 Gene3D G3DSA:3.30.160.160 8 54 9.1E-19 T 14-10-2018 TSH58p_08055 38df39e3b1c4fa79a10c924afae7ca3f 63 SUPERFAMILY SSF160113 7 56 1.03E-13 T 14-10-2018 IPR036913 YegP-like superfamily TSH58p_08055 38df39e3b1c4fa79a10c924afae7ca3f 63 Pfam PF07411 Domain of unknown function (DUF1508) 15 54 1.7E-12 T 14-10-2018 IPR010879 Domain of unknown function DUF1508 TSH58p_30665 61de5df9c25ffce82d7916f2e0ee5c47 369 SUPERFAMILY SSF50331 244 359 3.74E-12 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSH58p_30665 61de5df9c25ffce82d7916f2e0ee5c47 369 SUPERFAMILY SSF52540 10 248 4.83E-84 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_30665 61de5df9c25ffce82d7916f2e0ee5c47 369 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_30665 61de5df9c25ffce82d7916f2e0ee5c47 369 Gene3D G3DSA:3.40.50.300 10 256 1.2E-76 T 14-10-2018 TSH58p_30665 61de5df9c25ffce82d7916f2e0ee5c47 369 SMART SM00382 35 217 5.9E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_30665 61de5df9c25ffce82d7916f2e0ee5c47 369 Pfam PF00005 ABC transporter 26 168 5.5E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_30665 61de5df9c25ffce82d7916f2e0ee5c47 369 Pfam PF08402 TOBE domain 278 359 3.2E-10 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TSH58p_27860 862f06710d078503e26095028dba9d1f 283 SUPERFAMILY SSF56529 61 280 6.54E-82 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TSH58p_27860 862f06710d078503e26095028dba9d1f 283 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 72 279 1.1E-73 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 TSH58p_27860 862f06710d078503e26095028dba9d1f 283 Gene3D G3DSA:3.90.850.10 67 282 1.8E-87 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TSH58p_23200 61be269c9985a006fe78129afb546f97 486 Pfam PF07508 Recombinase 106 218 1.7E-18 T 14-10-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 TSH58p_23200 61be269c9985a006fe78129afb546f97 486 Pfam PF13408 Recombinase zinc beta ribbon domain 243 294 4.0E-9 T 14-10-2018 IPR025827 Recombinase zinc beta ribbon domain TSH58p_23200 61be269c9985a006fe78129afb546f97 486 SUPERFAMILY SSF53041 13 79 9.02E-7 T 14-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 TSH58p_23200 61be269c9985a006fe78129afb546f97 486 Gene3D G3DSA:1.10.10.2600 64 221 3.9E-12 T 14-10-2018 IPR038109 DNA-binding recombinase domain superfamily TSH58p_26060 9ecef3a637e0ce2c7f60672c739c7f9c 223 SMART SM00014 84 198 1.5E-18 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase TSH58p_26060 9ecef3a637e0ce2c7f60672c739c7f9c 223 Gene3D G3DSA:1.20.144.10 26 118 6.5E-8 T 14-10-2018 TSH58p_26060 9ecef3a637e0ce2c7f60672c739c7f9c 223 Gene3D G3DSA:1.20.144.10 121 219 9.8E-25 T 14-10-2018 TSH58p_26060 9ecef3a637e0ce2c7f60672c739c7f9c 223 Pfam PF01569 PAP2 superfamily 86 202 4.1E-24 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase TSH58p_26060 9ecef3a637e0ce2c7f60672c739c7f9c 223 SUPERFAMILY SSF48317 7 207 1.96E-38 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily TSH58p_23315 07e655b78d1bf15bea113779887bfd0c 256 SUPERFAMILY SSF110997 175 248 2.09E-7 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 TSH58p_23315 07e655b78d1bf15bea113779887bfd0c 256 Pfam PF05036 Sporulation related domain 174 249 7.5E-10 T 14-10-2018 IPR007730 Sporulation-like domain GO:0042834 TSH58p_27375 121a6b32e5a0e03d51cabe27cd0fcf33 212 Pfam PF02698 DUF218 domain 56 194 1.1E-12 T 14-10-2018 IPR003848 Domain of unknown function DUF218 TSH58p_01205 051d6685cd03c436bd45fa28aeed1e93 329 Hamap MF_00486 Methenyltetrahydromethanopterin cyclohydrolase [mch]. 1 329 133.883 T 14-10-2018 IPR003209 Methenyltetrahydromethanopterin cyclohydrolase GO:0006730|GO:0018759 KEGG: 00680+3.5.4.27|MetaCyc: PWY-1723|MetaCyc: PWY-7784 TSH58p_01205 051d6685cd03c436bd45fa28aeed1e93 329 Gene3D G3DSA:3.10.340.11 13 180 7.7E-111 T 14-10-2018 TSH58p_01205 051d6685cd03c436bd45fa28aeed1e93 329 Pfam PF02289 Cyclohydrolase (MCH) 12 325 3.0E-121 T 14-10-2018 IPR003209 Methenyltetrahydromethanopterin cyclohydrolase GO:0006730|GO:0018759 KEGG: 00680+3.5.4.27|MetaCyc: PWY-1723|MetaCyc: PWY-7784 TSH58p_01205 051d6685cd03c436bd45fa28aeed1e93 329 SUPERFAMILY SSF56199 12 325 2.22E-112 T 14-10-2018 TSH58p_01205 051d6685cd03c436bd45fa28aeed1e93 329 TIGRFAM TIGR03120 one_C_mch: methenyltetrahydromethanopterin cyclohydrolase 12 325 2.3E-114 T 14-10-2018 IPR003209 Methenyltetrahydromethanopterin cyclohydrolase GO:0006730|GO:0018759 KEGG: 00680+3.5.4.27|MetaCyc: PWY-1723|MetaCyc: PWY-7784 TSH58p_01205 051d6685cd03c436bd45fa28aeed1e93 329 Gene3D G3DSA:3.30.1030.10 53 325 7.7E-111 T 14-10-2018 TSH58p_20235 e94ab83940775b3b8fe1f0b19bc67d5e 260 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 186 201 - T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 TSH58p_20235 e94ab83940775b3b8fe1f0b19bc67d5e 260 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 179 191 1.4E-19 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 TSH58p_20235 e94ab83940775b3b8fe1f0b19bc67d5e 260 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 126 140 1.4E-19 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 TSH58p_20235 e94ab83940775b3b8fe1f0b19bc67d5e 260 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 114 126 1.4E-19 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 TSH58p_20235 e94ab83940775b3b8fe1f0b19bc67d5e 260 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 247 257 1.4E-19 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 TSH58p_20235 e94ab83940775b3b8fe1f0b19bc67d5e 260 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 54 63 1.4E-19 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 TSH58p_20235 e94ab83940775b3b8fe1f0b19bc67d5e 260 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 154 166 1.4E-19 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 TSH58p_20235 e94ab83940775b3b8fe1f0b19bc67d5e 260 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 58 257 9.9E-85 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 TSH58p_20235 e94ab83940775b3b8fe1f0b19bc67d5e 260 Pfam PF00813 FliP family 58 253 3.0E-78 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 TSH58p_20235 e94ab83940775b3b8fe1f0b19bc67d5e 260 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 186 206 3.8E-65 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 TSH58p_20235 e94ab83940775b3b8fe1f0b19bc67d5e 260 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 207 228 3.8E-65 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 TSH58p_20235 e94ab83940775b3b8fe1f0b19bc67d5e 260 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 75 95 3.8E-65 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 TSH58p_20235 e94ab83940775b3b8fe1f0b19bc67d5e 260 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 231 256 3.8E-65 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 TSH58p_20235 e94ab83940775b3b8fe1f0b19bc67d5e 260 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 95 114 3.8E-65 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 TSH58p_20235 e94ab83940775b3b8fe1f0b19bc67d5e 260 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 56 75 3.8E-65 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 TSH58p_07225 683c00347b8c9c791038bb543a87bf72 450 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 5 435 3.1E-39 T 14-10-2018 IPR024455 Phage capsid TSH58p_07225 683c00347b8c9c791038bb543a87bf72 450 Pfam PF05065 Phage capsid family 155 435 3.5E-33 T 14-10-2018 IPR024455 Phage capsid TSH58p_07225 683c00347b8c9c791038bb543a87bf72 450 SUPERFAMILY SSF56563 150 437 3.79E-34 T 14-10-2018 TSH58p_06980 4050a97acf9e868abb559275d01d4b24 358 Gene3D G3DSA:3.40.50.2000 188 335 2.1E-7 T 14-10-2018 TSH58p_06980 4050a97acf9e868abb559275d01d4b24 358 SUPERFAMILY SSF53756 2 350 9.42E-13 T 14-10-2018 TSH58p_06980 4050a97acf9e868abb559275d01d4b24 358 Pfam PF13524 Glycosyl transferases group 1 255 347 9.9E-18 T 14-10-2018 TSH58p_07920 c369c1ed9637efd98ea2989baa096878 74 PRINTS PR00124 ATP synthase C subunit signature 47 72 7.6E-28 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_07920 c369c1ed9637efd98ea2989baa096878 74 PRINTS PR00124 ATP synthase C subunit signature 9 28 7.6E-28 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_07920 c369c1ed9637efd98ea2989baa096878 74 PRINTS PR00124 ATP synthase C subunit signature 30 45 7.6E-28 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_07920 c369c1ed9637efd98ea2989baa096878 74 Hamap MF_01396 ATP synthase subunit c [atpH]. 4 72 14.368 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_07920 c369c1ed9637efd98ea2989baa096878 74 SUPERFAMILY SSF81333 5 74 5.89E-18 T 14-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily TSH58p_07920 c369c1ed9637efd98ea2989baa096878 74 Pfam PF00137 ATP synthase subunit C 10 71 3.1E-12 T 14-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 TSH58p_07920 c369c1ed9637efd98ea2989baa096878 74 Gene3D G3DSA:1.20.20.10 3 74 3.9E-25 T 14-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_07920 c369c1ed9637efd98ea2989baa096878 74 ProSitePatterns PS00605 ATP synthase c subunit signature. 37 58 - T 14-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TSH58p_14640 9d567bbc9c03c8a31be5fedeea472159 149 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 11 149 1.6E-36 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 TSH58p_14640 9d567bbc9c03c8a31be5fedeea472159 149 Pfam PF00364 Biotin-requiring enzyme 76 148 1.4E-20 T 14-10-2018 IPR000089 Biotin/lipoyl attachment TSH58p_14640 9d567bbc9c03c8a31be5fedeea472159 149 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 110 123 3.6E-13 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 TSH58p_14640 9d567bbc9c03c8a31be5fedeea472159 149 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 95 109 3.6E-13 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 TSH58p_14640 9d567bbc9c03c8a31be5fedeea472159 149 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 78 91 3.6E-13 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 TSH58p_14640 9d567bbc9c03c8a31be5fedeea472159 149 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 105 122 - T 14-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TSH58p_14640 9d567bbc9c03c8a31be5fedeea472159 149 Gene3D G3DSA:2.40.50.100 72 149 2.2E-27 T 14-10-2018 TSH58p_14640 9d567bbc9c03c8a31be5fedeea472159 149 SUPERFAMILY SSF51230 74 149 9.55E-23 T 14-10-2018 IPR011053 Single hybrid motif TSH58p_03740 a5df49dfabb7816473cb9194b87fbe7d 355 Pfam PF13565 Homeodomain-like domain 59 130 7.4E-11 T 14-10-2018 TSH58p_03740 a5df49dfabb7816473cb9194b87fbe7d 355 SUPERFAMILY SSF53098 203 345 4.05E-5 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily TSH58p_03740 a5df49dfabb7816473cb9194b87fbe7d 355 SUPERFAMILY SSF46689 23 132 3.05E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_03740 a5df49dfabb7816473cb9194b87fbe7d 355 Pfam PF13358 DDE superfamily endonuclease 171 317 9.6E-20 T 14-10-2018 IPR038717 Tc1-like transposase, DDE domain TSH58p_27295 694d622aa6fe2a401332f3d197492e67 212 SUPERFAMILY SSF110857 40 154 8.89E-13 T 14-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily TSH58p_27295 694d622aa6fe2a401332f3d197492e67 212 Pfam PF04752 ChaC-like protein 40 209 1.3E-51 T 14-10-2018 IPR006840 Glutathione-specific gamma-glutamylcyclotransferase GO:0003839|GO:0006751 KEGG: 00480+4.3.2.7|MetaCyc: PWY-7942|Reactome: R-HSA-174403 TSH58p_27295 694d622aa6fe2a401332f3d197492e67 212 Gene3D G3DSA:3.10.490.10 25 203 5.0E-11 T 14-10-2018 TSH58p_31495 62dcdd1ec1c04ce6e6b640a0940b97b4 132 Gene3D G3DSA:3.30.1330.40 1 131 8.9E-42 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TSH58p_31495 62dcdd1ec1c04ce6e6b640a0940b97b4 132 SUPERFAMILY SSF55298 10 129 1.35E-35 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TSH58p_31495 62dcdd1ec1c04ce6e6b640a0940b97b4 132 Pfam PF01042 Endoribonuclease L-PSP 13 127 2.4E-30 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 TSH58p_21105 7c14df37c7685d84e53a870226d43da9 266 Gene3D G3DSA:1.10.3720.10 1 255 6.7E-43 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_21105 7c14df37c7685d84e53a870226d43da9 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 252 3.4E-11 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_21105 7c14df37c7685d84e53a870226d43da9 266 SUPERFAMILY SSF161098 4 252 4.86E-48 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_29645 9cfdc7952ea6f116ddda922a3cdc25e7 177 Pfam PF12802 MarR family 57 114 7.8E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_29645 9cfdc7952ea6f116ddda922a3cdc25e7 177 SUPERFAMILY SSF46785 25 169 2.5E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_29645 9cfdc7952ea6f116ddda922a3cdc25e7 177 SMART SM00347 51 150 3.4E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_29645 9cfdc7952ea6f116ddda922a3cdc25e7 177 Gene3D G3DSA:1.10.10.10 3 167 6.7E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_29645 9cfdc7952ea6f116ddda922a3cdc25e7 177 ProSitePatterns PS01117 MarR-type HTH domain signature. 89 123 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site TSH58p_08080 ea8ba8676e792f9aa9eba0c423dafaa5 155 SUPERFAMILY SSF55298 4 154 1.88E-55 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TSH58p_08080 ea8ba8676e792f9aa9eba0c423dafaa5 155 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 6 149 1.5E-39 T 14-10-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like TSH58p_08080 ea8ba8676e792f9aa9eba0c423dafaa5 155 Gene3D G3DSA:3.30.1330.40 1 154 1.1E-62 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TSH58p_17570 93a8e4664c1cc408324d470f0444b0ba 381 Gene3D G3DSA:2.40.10.10 266 357 4.2E-8 T 14-10-2018 TSH58p_17570 93a8e4664c1cc408324d470f0444b0ba 381 SUPERFAMILY SSF50494 177 328 6.99E-23 T 14-10-2018 IPR009003 Peptidase S1, PA clan TSH58p_17570 93a8e4664c1cc408324d470f0444b0ba 381 Gene3D G3DSA:2.40.10.10 172 265 5.0E-8 T 14-10-2018 TSH58p_17570 93a8e4664c1cc408324d470f0444b0ba 381 Pfam PF13365 Trypsin-like peptidase domain 180 326 9.5E-13 T 14-10-2018 TSH58p_06690 be0564f5a9f2599e5ff4d35a722c924c 339 Pfam PF00072 Response regulator receiver domain 11 125 4.0E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_06690 be0564f5a9f2599e5ff4d35a722c924c 339 SMART SM00448 9 125 7.6E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_06690 be0564f5a9f2599e5ff4d35a722c924c 339 Gene3D G3DSA:3.40.50.2300 8 152 1.4E-29 T 14-10-2018 TSH58p_06690 be0564f5a9f2599e5ff4d35a722c924c 339 SUPERFAMILY SSF52172 8 134 2.56E-32 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_15020 fd393e602e26c310dc6e769e5b24452e 146 Gene3D G3DSA:1.10.10.10 4 146 8.9E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_15020 fd393e602e26c310dc6e769e5b24452e 146 SMART SM00347 35 135 3.8E-20 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_15020 fd393e602e26c310dc6e769e5b24452e 146 SUPERFAMILY SSF46785 7 145 1.32E-30 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_15020 fd393e602e26c310dc6e769e5b24452e 146 Pfam PF12802 MarR family 41 99 9.9E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_32520 0d4b4306d7e59e590cf013fdd0260af8 335 Pfam PF02653 Branched-chain amino acid transport system / permease component 50 313 1.3E-32 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_23365 60cfc04b86f333b43a34e9517865fd0a 171 Gene3D G3DSA:2.30.110.20 2 166 4.2E-18 T 14-10-2018 IPR036624 Hcp1-like superfamily TSH58p_23365 60cfc04b86f333b43a34e9517865fd0a 171 SUPERFAMILY SSF141452 4 166 8.5E-19 T 14-10-2018 IPR036624 Hcp1-like superfamily TSH58p_23365 60cfc04b86f333b43a34e9517865fd0a 171 Pfam PF05638 Type VI secretion system effector, Hcp 7 144 5.4E-14 T 14-10-2018 IPR008514 Type VI secretion system effector, Hcp TSH58p_21110 9a16cd0821cb2f00e061dbdf8be6e528 351 PIRSF PIRSF036979 50 344 2.2E-92 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 TSH58p_21110 9a16cd0821cb2f00e061dbdf8be6e528 351 Gene3D G3DSA:3.40.800.10 33 350 5.7E-103 T 14-10-2018 TSH58p_21110 9a16cd0821cb2f00e061dbdf8be6e528 351 SUPERFAMILY SSF52768 35 341 2.88E-87 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily TSH58p_21110 9a16cd0821cb2f00e061dbdf8be6e528 351 TIGRFAM TIGR01230 agmatinase: agmatinase 69 337 2.6E-54 T 14-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 TSH58p_21110 9a16cd0821cb2f00e061dbdf8be6e528 351 ProSitePatterns PS01053 Arginase family signature. 268 289 - T 14-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 TSH58p_21110 9a16cd0821cb2f00e061dbdf8be6e528 351 Pfam PF00491 Arginase family 69 337 1.5E-84 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 TSH58p_16450 bb2a93de813e71879f60e2ea3729e758 524 SUPERFAMILY SSF158472 181 231 4.32E-12 T 14-10-2018 TSH58p_16450 bb2a93de813e71879f60e2ea3729e758 524 Gene3D G3DSA:1.20.1480.50 145 240 5.0E-15 T 14-10-2018 TSH58p_16450 bb2a93de813e71879f60e2ea3729e758 524 SMART SM00304 181 233 9.6E-16 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_16450 bb2a93de813e71879f60e2ea3729e758 524 SMART SM00331 278 506 7.1E-6 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSH58p_16450 bb2a93de813e71879f60e2ea3729e758 524 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 303 506 8.6E-20 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSH58p_16450 bb2a93de813e71879f60e2ea3729e758 524 Pfam PF00672 HAMP domain 181 229 8.6E-15 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_16450 bb2a93de813e71879f60e2ea3729e758 524 Gene3D G3DSA:3.60.40.10 242 507 1.1E-54 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSH58p_08770 ce3e4c03cc05a58536482225d18ab405 223 SUPERFAMILY SSF48498 100 218 2.84E-7 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TSH58p_08770 ce3e4c03cc05a58536482225d18ab405 223 Gene3D G3DSA:1.10.357.10 82 223 1.1E-9 T 14-10-2018 TSH58p_08770 ce3e4c03cc05a58536482225d18ab405 223 Gene3D G3DSA:1.10.10.60 22 81 3.1E-19 T 14-10-2018 TSH58p_08770 ce3e4c03cc05a58536482225d18ab405 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 38 84 3.1E-17 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_08770 ce3e4c03cc05a58536482225d18ab405 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 51 1.9E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_08770 ce3e4c03cc05a58536482225d18ab405 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 59 82 1.9E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_08770 ce3e4c03cc05a58536482225d18ab405 223 SUPERFAMILY SSF46689 26 90 2.15E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_16005 f72c9ec751584db86c1f24d7a3876a95 691 Pfam PF06082 Exopolysaccharide biosynthesis protein YbjH 25 672 6.6E-165 T 14-10-2018 IPR010344 Exopolysaccharide biosynthesis protein YbjH TSH58p_03730 b9f5c2f7ce6eb4ddf011094f4e58bc89 88 SUPERFAMILY SSF160537 9 77 9.94E-6 T 14-10-2018 IPR036751 Stage V sporulation protein G superfamily GO:0030435 TSH58p_30805 f7d382960889c4b55255446bd04f2fe4 260 SUPERFAMILY SSF89562 52 226 6.41E-35 T 14-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily TSH58p_30805 f7d382960889c4b55255446bd04f2fe4 260 Pfam PF03737 Aldolase/RraA 49 214 1.8E-31 T 14-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein TSH58p_30805 f7d382960889c4b55255446bd04f2fe4 260 Gene3D G3DSA:3.50.30.100 19 237 5.7E-51 T 14-10-2018 TSH58p_28400 45efe8b29662b570e01058dc418dde1a 715 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 19 690 1.2E-289 T 14-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 TSH58p_28400 45efe8b29662b570e01058dc418dde1a 715 Gene3D G3DSA:3.30.870.10 507 690 3.5E-65 T 14-10-2018 TSH58p_28400 45efe8b29662b570e01058dc418dde1a 715 Gene3D G3DSA:3.30.870.10 329 506 1.1E-72 T 14-10-2018 TSH58p_28400 45efe8b29662b570e01058dc418dde1a 715 Gene3D G3DSA:3.30.1840.10 13 318 6.2E-99 T 14-10-2018 IPR036830 Polyphosphate kinase middle domain superfamily KEGG: 00190+2.7.4.1 TSH58p_28400 45efe8b29662b570e01058dc418dde1a 715 SUPERFAMILY SSF140356 17 120 2.88E-38 T 14-10-2018 IPR036832 Polyphosphate kinase N-terminal domain superfamily KEGG: 00190+2.7.4.1 TSH58p_28400 45efe8b29662b570e01058dc418dde1a 715 Pfam PF13089 Polyphosphate kinase N-terminal domain 20 124 1.6E-38 T 14-10-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 TSH58p_28400 45efe8b29662b570e01058dc418dde1a 715 SUPERFAMILY SSF56024 507 688 5.61E-67 T 14-10-2018 TSH58p_28400 45efe8b29662b570e01058dc418dde1a 715 SUPERFAMILY SSF143724 122 319 7.65E-59 T 14-10-2018 TSH58p_28400 45efe8b29662b570e01058dc418dde1a 715 Hamap MF_00347 Polyphosphate kinase [ppk]. 17 693 27.884 T 14-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 TSH58p_28400 45efe8b29662b570e01058dc418dde1a 715 SUPERFAMILY SSF56024 327 503 2.89E-58 T 14-10-2018 TSH58p_28400 45efe8b29662b570e01058dc418dde1a 715 Pfam PF13090 Polyphosphate kinase C-terminal domain 337 688 3.2E-154 T 14-10-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 TSH58p_28400 45efe8b29662b570e01058dc418dde1a 715 PIRSF PIRSF015589 2 705 3.6E-267 T 14-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 TSH58p_28400 45efe8b29662b570e01058dc418dde1a 715 Pfam PF02503 Polyphosphate kinase middle domain 134 327 1.1E-56 T 14-10-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 TSH58p_11910 31ccd8cf0dc6e82d254780acaf287059 355 SUPERFAMILY SSF46589 11 97 2.04E-20 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 TSH58p_11910 31ccd8cf0dc6e82d254780acaf287059 355 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 18 85 6.4E-23 T 14-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 TSH58p_11910 31ccd8cf0dc6e82d254780acaf287059 355 Gene3D G3DSA:3.30.930.10 6 341 1.6E-116 T 14-10-2018 TSH58p_11910 31ccd8cf0dc6e82d254780acaf287059 355 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 6 339 47.125 T 14-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 TSH58p_11910 31ccd8cf0dc6e82d254780acaf287059 355 SUPERFAMILY SSF55681 90 340 6.73E-79 T 14-10-2018 TSH58p_11910 31ccd8cf0dc6e82d254780acaf287059 355 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 38 338 2.4E-102 T 14-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TSH58p_11910 31ccd8cf0dc6e82d254780acaf287059 355 Pfam PF01409 tRNA synthetases class II core domain (F) 90 338 3.7E-103 T 14-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 TSH58p_19215 2ceba9978258b2cee6538ae06b6dab1d 403 Pfam PF07690 Major Facilitator Superfamily 32 288 1.3E-21 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_19215 2ceba9978258b2cee6538ae06b6dab1d 403 SUPERFAMILY SSF103473 17 402 1.44E-51 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_19215 2ceba9978258b2cee6538ae06b6dab1d 403 Gene3D G3DSA:1.20.1250.20 20 400 1.7E-40 T 14-10-2018 TSH58p_12525 1982a9b05f08315446cb70f78e4ea95e 247 Gene3D G3DSA:3.40.50.2020 120 246 9.2E-19 T 14-10-2018 TSH58p_12525 1982a9b05f08315446cb70f78e4ea95e 247 SUPERFAMILY SSF53271 69 243 2.23E-35 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like TSH58p_12525 1982a9b05f08315446cb70f78e4ea95e 247 Pfam PF00156 Phosphoribosyl transferase domain 181 242 2.7E-9 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TSH58p_20315 789feae6e7c480f098cc139758d389b4 294 Gene3D G3DSA:2.60.200.40 126 284 8.0E-42 T 14-10-2018 TSH58p_20315 789feae6e7c480f098cc139758d389b4 294 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 6 292 1.2E-50 T 14-10-2018 IPR005218 Diacylglycerol/lipid kinase TSH58p_20315 789feae6e7c480f098cc139758d389b4 294 SMART SM00046 7 129 1.9E-9 T 14-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 TSH58p_20315 789feae6e7c480f098cc139758d389b4 294 Pfam PF00781 Diacylglycerol kinase catalytic domain 7 126 3.4E-25 T 14-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 TSH58p_20315 789feae6e7c480f098cc139758d389b4 294 Gene3D G3DSA:3.40.50.10330 1 125 4.0E-32 T 14-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 TSH58p_20315 789feae6e7c480f098cc139758d389b4 294 SUPERFAMILY SSF111331 5 293 2.09E-74 T 14-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily TSH58p_31130 ff6be9156c52af45af8968c54c4e3b13 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 290 1.3E-31 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_31130 ff6be9156c52af45af8968c54c4e3b13 294 Gene3D G3DSA:1.10.3720.10 81 286 3.4E-22 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_31130 ff6be9156c52af45af8968c54c4e3b13 294 SUPERFAMILY SSF161098 86 272 4.32E-26 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_08365 17b3974d7fd9353a4267c3764b6ac685 526 Pfam PF01019 Gamma-glutamyltranspeptidase 22 512 1.9E-101 T 14-10-2018 TSH58p_08365 17b3974d7fd9353a4267c3764b6ac685 526 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 117 136 8.3E-30 T 14-10-2018 TSH58p_08365 17b3974d7fd9353a4267c3764b6ac685 526 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 29 54 8.3E-30 T 14-10-2018 TSH58p_08365 17b3974d7fd9353a4267c3764b6ac685 526 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 239 258 8.3E-30 T 14-10-2018 TSH58p_08365 17b3974d7fd9353a4267c3764b6ac685 526 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 413 430 8.3E-30 T 14-10-2018 TSH58p_08365 17b3974d7fd9353a4267c3764b6ac685 526 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 386 401 8.3E-30 T 14-10-2018 TSH58p_08365 17b3974d7fd9353a4267c3764b6ac685 526 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 331 349 8.3E-30 T 14-10-2018 TSH58p_08365 17b3974d7fd9353a4267c3764b6ac685 526 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 355 373 8.3E-30 T 14-10-2018 TSH58p_08365 17b3974d7fd9353a4267c3764b6ac685 526 SUPERFAMILY SSF56235 3 515 2.12E-123 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_08365 17b3974d7fd9353a4267c3764b6ac685 526 Gene3D G3DSA:3.60.20.40 331 515 1.8E-52 T 14-10-2018 TSH58p_08365 17b3974d7fd9353a4267c3764b6ac685 526 Gene3D G3DSA:1.10.246.130 226 329 2.2E-17 T 14-10-2018 TSH58p_04630 4756a6f7a15c88cb979ae0eeca764ae0 91 Pfam PF00216 Bacterial DNA-binding protein 1 90 4.0E-33 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_04630 4756a6f7a15c88cb979ae0eeca764ae0 91 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 2.7E-16 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_04630 4756a6f7a15c88cb979ae0eeca764ae0 91 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 2.7E-16 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_04630 4756a6f7a15c88cb979ae0eeca764ae0 91 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 2.7E-16 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_04630 4756a6f7a15c88cb979ae0eeca764ae0 91 Gene3D G3DSA:4.10.520.10 1 91 1.5E-34 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 TSH58p_04630 4756a6f7a15c88cb979ae0eeca764ae0 91 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 14-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 TSH58p_04630 4756a6f7a15c88cb979ae0eeca764ae0 91 SMART SM00411 1 90 8.9E-40 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_04630 4756a6f7a15c88cb979ae0eeca764ae0 91 SUPERFAMILY SSF47729 1 90 8.83E-31 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 TSH58p_15840 bf6a18187d5a4db97bd84528a41450e2 265 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 6 256 3.0E-51 T 14-10-2018 IPR005226 UPF0014 family TSH58p_15840 bf6a18187d5a4db97bd84528a41450e2 265 Pfam PF03649 Uncharacterised protein family (UPF0014) 8 248 2.3E-81 T 14-10-2018 IPR005226 UPF0014 family TSH58p_14510 275d18b880030ecdf7e7b42d39779ed5 219 SUPERFAMILY SSF53474 18 215 3.95E-32 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_14510 275d18b880030ecdf7e7b42d39779ed5 219 Gene3D G3DSA:3.40.50.1820 12 216 1.2E-30 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_14510 275d18b880030ecdf7e7b42d39779ed5 219 Pfam PF01738 Dienelactone hydrolase family 107 200 2.3E-6 T 14-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 TSH58p_07835 0d97f155a4efdbeabb1bd538e441a2fa 394 Pfam PF13524 Glycosyl transferases group 1 281 384 1.5E-8 T 14-10-2018 TSH58p_07835 0d97f155a4efdbeabb1bd538e441a2fa 394 SUPERFAMILY SSF53756 128 394 4.13E-30 T 14-10-2018 TSH58p_07835 0d97f155a4efdbeabb1bd538e441a2fa 394 Gene3D G3DSA:3.40.50.2000 171 394 1.9E-29 T 14-10-2018 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 12 529 2.5E-204 T 14-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 SUPERFAMILY SSF50249 115 194 3.35E-12 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 Gene3D G3DSA:2.40.50.140 278 366 2.2E-28 T 14-10-2018 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 Gene3D G3DSA:2.40.50.140 367 453 3.6E-24 T 14-10-2018 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 SUPERFAMILY SSF50249 198 284 1.04E-26 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 Gene3D G3DSA:2.40.50.140 454 537 5.3E-19 T 14-10-2018 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 PRINTS PR00681 Ribosomal protein S1 signature 164 184 5.6E-85 T 14-10-2018 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 PRINTS PR00681 Ribosomal protein S1 signature 30 48 5.6E-85 T 14-10-2018 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 PRINTS PR00681 Ribosomal protein S1 signature 299 318 5.6E-85 T 14-10-2018 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 PRINTS PR00681 Ribosomal protein S1 signature 48 62 5.6E-85 T 14-10-2018 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 PRINTS PR00681 Ribosomal protein S1 signature 339 357 5.6E-85 T 14-10-2018 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 PRINTS PR00681 Ribosomal protein S1 signature 135 152 5.6E-85 T 14-10-2018 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 PRINTS PR00681 Ribosomal protein S1 signature 93 112 5.6E-85 T 14-10-2018 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 PRINTS PR00681 Ribosomal protein S1 signature 117 133 5.6E-85 T 14-10-2018 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 PRINTS PR00681 Ribosomal protein S1 signature 221 242 5.6E-85 T 14-10-2018 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 Gene3D G3DSA:2.40.50.140 16 109 1.0E-15 T 14-10-2018 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 SUPERFAMILY SSF50249 264 368 3.58E-26 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 SUPERFAMILY SSF50249 442 543 1.64E-21 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 Gene3D G3DSA:2.40.50.140 195 277 3.7E-28 T 14-10-2018 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 SUPERFAMILY SSF50249 351 449 1.27E-22 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 SUPERFAMILY SSF50249 17 121 7.8E-19 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 Pfam PF00575 S1 RNA binding domain 114 180 1.4E-8 T 14-10-2018 IPR003029 S1 domain GO:0003676 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 Pfam PF00575 S1 RNA binding domain 370 443 1.7E-20 T 14-10-2018 IPR003029 S1 domain GO:0003676 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 Pfam PF00575 S1 RNA binding domain 287 356 7.3E-20 T 14-10-2018 IPR003029 S1 domain GO:0003676 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 Pfam PF00575 S1 RNA binding domain 458 529 3.7E-18 T 14-10-2018 IPR003029 S1 domain GO:0003676 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 Pfam PF00575 S1 RNA binding domain 29 95 2.2E-7 T 14-10-2018 IPR003029 S1 domain GO:0003676 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 Pfam PF00575 S1 RNA binding domain 199 269 4.7E-20 T 14-10-2018 IPR003029 S1 domain GO:0003676 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 SMART SM00316 199 269 2.2E-28 T 14-10-2018 IPR022967 RNA-binding domain, S1 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 SMART SM00316 284 356 6.7E-25 T 14-10-2018 IPR022967 RNA-binding domain, S1 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 SMART SM00316 28 96 1.7E-9 T 14-10-2018 IPR022967 RNA-binding domain, S1 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 SMART SM00316 112 180 4.6E-5 T 14-10-2018 IPR022967 RNA-binding domain, S1 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 SMART SM00316 371 443 3.5E-21 T 14-10-2018 IPR022967 RNA-binding domain, S1 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 SMART SM00316 458 529 1.4E-21 T 14-10-2018 IPR022967 RNA-binding domain, S1 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 PIRSF PIRSF002111 364 549 7.6E-46 T 14-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 TSH58p_12745 696a76eac02c4a093eedf704a8d7b52b 569 PIRSF PIRSF002111 1 420 8.6E-175 T 14-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 TSH58p_26085 c7983ec76f544bb46621bb6ee31f2192 228 Gene3D G3DSA:4.10.860.20 181 228 1.8E-16 T 14-10-2018 TSH58p_26085 c7983ec76f544bb46621bb6ee31f2192 228 Gene3D G3DSA:2.60.120.620 1 179 9.1E-40 T 14-10-2018 TSH58p_26085 c7983ec76f544bb46621bb6ee31f2192 228 SMART SM00702 2 178 1.2E-15 T 14-10-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 TSH58p_26085 c7983ec76f544bb46621bb6ee31f2192 228 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 83 176 1.6E-11 T 14-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 TSH58p_26085 c7983ec76f544bb46621bb6ee31f2192 228 Hamap MF_00657 PKHD-type hydroxylase YbiX [ybiX]. 1 228 44.139 T 14-10-2018 IPR023550 PKHD-type hydroxylase GO:0016706|GO:0055114 TSH58p_30470 187582f377597ebf937846d92277fd7a 212 SUPERFAMILY SSF103025 80 203 3.14E-10 T 14-10-2018 TSH58p_30470 187582f377597ebf937846d92277fd7a 212 Gene3D G3DSA:3.30.1360.120 36 200 5.0E-35 T 14-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 TSH58p_30470 187582f377597ebf937846d92277fd7a 212 Pfam PF04268 Sarcosine oxidase, gamma subunit family 52 200 3.8E-20 T 14-10-2018 IPR007375 Sarcosine oxidase, gamma subunit KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 TSH58p_30470 187582f377597ebf937846d92277fd7a 212 Gene3D G3DSA:3.30.70.1520 39 121 5.0E-35 T 14-10-2018 TSH58p_21930 07f8d05625eb94ec2878de7e6641584b 118 SUPERFAMILY SSF117916 21 116 6.54E-31 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TSH58p_21930 07f8d05625eb94ec2878de7e6641584b 118 Gene3D G3DSA:3.30.300.130 13 117 1.5E-36 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TSH58p_21930 07f8d05625eb94ec2878de7e6641584b 118 Pfam PF01883 Iron-sulfur cluster assembly protein 23 95 3.0E-18 T 14-10-2018 IPR002744 MIP18 family-like TSH58p_21930 07f8d05625eb94ec2878de7e6641584b 118 TIGRFAM TIGR02945 SUF_assoc: FeS assembly SUF system protein 21 118 5.1E-43 T 14-10-2018 IPR014291 SUF system FeS cluster assembly associated TSH58p_01705 f37df57087f8088e81e934ca9e2b6d0d 181 Gene3D G3DSA:1.10.443.10 2 156 3.0E-12 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TSH58p_01705 f37df57087f8088e81e934ca9e2b6d0d 181 SUPERFAMILY SSF56349 22 149 7.65E-15 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TSH58p_01705 f37df57087f8088e81e934ca9e2b6d0d 181 Pfam PF00589 Phage integrase family 10 149 6.3E-7 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TSH58p_01915 f34d56c97bc2b6bc47e5c36a3f09cf62 262 PIRSF PIRSF006241 1 260 6.4E-95 T 14-10-2018 IPR026040 Hydroxypyruvate isomerase-like TSH58p_01915 f34d56c97bc2b6bc47e5c36a3f09cf62 262 SUPERFAMILY SSF51658 1 256 4.45E-85 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily TSH58p_01915 f34d56c97bc2b6bc47e5c36a3f09cf62 262 Gene3D G3DSA:3.20.20.150 1 261 2.4E-81 T 14-10-2018 TSH58p_01915 f34d56c97bc2b6bc47e5c36a3f09cf62 262 Pfam PF01261 Xylose isomerase-like TIM barrel 21 217 6.4E-35 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TSH58p_18835 da70bb109b35167282021ec208ca4c33 501 SUPERFAMILY SSF51735 22 279 4.72E-66 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_18835 da70bb109b35167282021ec208ca4c33 501 SUPERFAMILY SSF48179 283 500 2.41E-43 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_18835 da70bb109b35167282021ec208ca4c33 501 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 214 473 5.3E-53 T 14-10-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 TSH58p_18835 da70bb109b35167282021ec208ca4c33 501 PRINTS PR00084 Mannitol dehydrogenase signature 174 187 2.8E-8 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 TSH58p_18835 da70bb109b35167282021ec208ca4c33 501 PRINTS PR00084 Mannitol dehydrogenase signature 215 228 2.8E-8 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 TSH58p_18835 da70bb109b35167282021ec208ca4c33 501 PRINTS PR00084 Mannitol dehydrogenase signature 245 260 2.8E-8 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 TSH58p_18835 da70bb109b35167282021ec208ca4c33 501 PRINTS PR00084 Mannitol dehydrogenase signature 29 39 2.8E-8 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 TSH58p_18835 da70bb109b35167282021ec208ca4c33 501 Gene3D G3DSA:1.10.1040.10 282 500 2.1E-58 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSH58p_18835 da70bb109b35167282021ec208ca4c33 501 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 28 143 2.0E-13 T 14-10-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 TSH58p_18835 da70bb109b35167282021ec208ca4c33 501 Gene3D G3DSA:3.40.50.720 15 279 5.0E-53 T 14-10-2018 TSH58p_12335 715b44e16247c3419016f4e7215efc42 515 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 389 500 3.2E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_12335 715b44e16247c3419016f4e7215efc42 515 SUPERFAMILY SSF47384 236 343 5.49E-17 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_12335 715b44e16247c3419016f4e7215efc42 515 SUPERFAMILY SSF55874 332 499 1.24E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_12335 715b44e16247c3419016f4e7215efc42 515 Gene3D G3DSA:3.30.565.10 341 502 4.0E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_12335 715b44e16247c3419016f4e7215efc42 515 Pfam PF00512 His Kinase A (phospho-acceptor) domain 252 342 1.1E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_12335 715b44e16247c3419016f4e7215efc42 515 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 440 5.1E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_12335 715b44e16247c3419016f4e7215efc42 515 PRINTS PR00344 Bacterial sensor protein C-terminal signature 461 479 5.1E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_12335 715b44e16247c3419016f4e7215efc42 515 PRINTS PR00344 Bacterial sensor protein C-terminal signature 485 498 5.1E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_12335 715b44e16247c3419016f4e7215efc42 515 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 454 5.1E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_12335 715b44e16247c3419016f4e7215efc42 515 SMART SM00387 388 501 3.7E-34 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_12335 715b44e16247c3419016f4e7215efc42 515 SMART SM00388 252 342 3.7E-17 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_12335 715b44e16247c3419016f4e7215efc42 515 Gene3D G3DSA:1.10.287.130 219 340 3.0E-23 T 14-10-2018 TSH58p_32295 a7cad04c6776cbc4c4ccdf0e41a831dd 169 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 24 156 1.2E-30 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ TSH58p_14460 c805bbe1f6650544566802247d57b9fa 71 Pfam PF09413 Putative prokaryotic signal transducing protein 1 65 4.7E-20 T 14-10-2018 IPR018551 Domain of unknown function DUF2007 TSH58p_14460 c805bbe1f6650544566802247d57b9fa 71 SUPERFAMILY SSF54913 1 68 8.89E-23 T 14-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TSH58p_14460 c805bbe1f6650544566802247d57b9fa 71 Gene3D G3DSA:3.30.70.790 1 70 5.7E-30 T 14-10-2018 IPR036675 UreE, C-terminal domain superfamily GO:0016151|GO:0019627|GO:0065003 TSH58p_16800 600c583b04630c5a58c0de1be27691bc 364 Pfam PF03060 Nitronate monooxygenase 14 351 3.5E-92 T 14-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 TSH58p_16800 600c583b04630c5a58c0de1be27691bc 364 Gene3D G3DSA:3.20.20.70 3 360 3.2E-113 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_16800 600c583b04630c5a58c0de1be27691bc 364 SUPERFAMILY SSF51412 3 357 6.87E-66 T 14-10-2018 TSH58p_25870 56577aafcec2d7931d309af73fefb8c2 299 Gene3D G3DSA:2.60.450.10 133 265 8.7E-6 T 14-10-2018 TSH58p_25870 56577aafcec2d7931d309af73fefb8c2 299 Pfam PF03968 OstA-like protein 143 248 3.8E-5 T 14-10-2018 IPR005653 Organic solvent tolerance-like, N-terminal TSH58p_23955 d1e670f4b6f767d7b102dc23c37b7561 299 Pfam PF01882 Protein of unknown function DUF58 51 138 8.6E-18 T 14-10-2018 IPR002881 Domain of unknown function DUF58 TSH58p_06415 713c21e90976c5ec823f23dcb1c4240c 301 SUPERFAMILY SSF103481 197 297 3.4E-14 T 14-10-2018 TSH58p_06415 713c21e90976c5ec823f23dcb1c4240c 301 SUPERFAMILY SSF103481 56 156 6.54E-15 T 14-10-2018 TSH58p_06415 713c21e90976c5ec823f23dcb1c4240c 301 Pfam PF00892 EamA-like transporter family 25 153 7.7E-14 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_06415 713c21e90976c5ec823f23dcb1c4240c 301 Pfam PF00892 EamA-like transporter family 163 292 3.9E-9 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_21975 8e1c8772f13cf3626f9cbe585bed6fa9 168 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 88 99 - T 14-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TSH58p_21975 8e1c8772f13cf3626f9cbe585bed6fa9 168 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 132 1.6E-37 T 14-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TSH58p_21975 8e1c8772f13cf3626f9cbe585bed6fa9 168 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 132 1.4E-40 T 14-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TSH58p_21975 8e1c8772f13cf3626f9cbe585bed6fa9 168 SUPERFAMILY SSF55083 1 156 6.28E-50 T 14-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TSH58p_21975 8e1c8772f13cf3626f9cbe585bed6fa9 168 Gene3D G3DSA:3.30.70.560 1 165 3.2E-53 T 14-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TSH58p_02040 82ec45201daca403384eaa81a9a64325 119 SUPERFAMILY SSF82093 33 105 3.01E-6 T 14-10-2018 IPR036127 CcmE-like superfamily GO:0005886|GO:0017003|GO:0017004 TSH58p_02040 82ec45201daca403384eaa81a9a64325 119 Pfam PF03100 CcmE 5 104 6.8E-6 T 14-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 TSH58p_02040 82ec45201daca403384eaa81a9a64325 119 Gene3D G3DSA:2.40.50.140 18 112 2.3E-6 T 14-10-2018 TSH58p_13570 65751c29c9eed4a4e7139d93d740e8ee 178 Pfam PF14358 Domain of unknown function (DUF4405) 12 63 1.6E-5 T 14-10-2018 IPR025517 Domain of unknown function DUF4405 TSH58p_10615 0e1eade05bf6094de060380877d5a2f0 239 Gene3D G3DSA:3.30.230.70 10 238 6.2E-58 T 14-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSH58p_10615 0e1eade05bf6094de060380877d5a2f0 239 SUPERFAMILY SSF55666 153 236 6.15E-23 T 14-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSH58p_10615 0e1eade05bf6094de060380877d5a2f0 239 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 236 1.7E-113 T 14-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 TSH58p_10615 0e1eade05bf6094de060380877d5a2f0 239 SUPERFAMILY SSF54211 1 181 4.35E-43 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSH58p_10615 0e1eade05bf6094de060380877d5a2f0 239 Hamap MF_00564 Ribonuclease PH [rph]. 11 237 43.315 T 14-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 TSH58p_10615 0e1eade05bf6094de060380877d5a2f0 239 Pfam PF03725 3' exoribonuclease family, domain 2 159 224 2.2E-9 T 14-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSH58p_10615 0e1eade05bf6094de060380877d5a2f0 239 Pfam PF01138 3' exoribonuclease family, domain 1 10 139 3.7E-21 T 14-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSH58p_10615 0e1eade05bf6094de060380877d5a2f0 239 ProSitePatterns PS01277 Ribonuclease PH signature. 116 129 - T 14-10-2018 IPR018336 Ribonuclease PH, conserved site TSH58p_13890 3db953fad391b67a31e111c7a6bed192 311 SUPERFAMILY SSF56281 5 307 6.96E-56 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_13890 3db953fad391b67a31e111c7a6bed192 311 TIGRFAM TIGR04558 SoxH_rel_PQQ_1: quinoprotein relay system zinc metallohydrolase 1 24 307 3.2E-130 T 14-10-2018 IPR030811 Quinoprotein relay system zinc metallohydrolase 1 TSH58p_13890 3db953fad391b67a31e111c7a6bed192 311 SMART SM00849 56 235 2.1E-11 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_13890 3db953fad391b67a31e111c7a6bed192 311 Pfam PF00753 Metallo-beta-lactamase superfamily 57 235 9.8E-12 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_13890 3db953fad391b67a31e111c7a6bed192 311 Gene3D G3DSA:3.60.15.10 30 254 1.5E-37 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_04970 0d7c679fd1d6f0d762d882e35c01ec32 290 Pfam PF05239 PRC-barrel domain 96 163 1.2E-11 T 14-10-2018 IPR027275 PRC-barrel domain TSH58p_04970 0d7c679fd1d6f0d762d882e35c01ec32 290 SUPERFAMILY SSF50346 97 209 4.71E-21 T 14-10-2018 IPR011033 PRC-barrel-like superfamily TSH58p_04970 0d7c679fd1d6f0d762d882e35c01ec32 290 Gene3D G3DSA:2.30.30.240 88 177 4.9E-23 T 14-10-2018 TSH58p_17380 e6265328f6e51289765ac7851dedf551 737 SUPERFAMILY SSF53335 9 699 1.27E-26 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_17380 e6265328f6e51289765ac7851dedf551 737 Gene3D G3DSA:3.40.50.150 3 216 8.7E-18 T 14-10-2018 TSH58p_17380 e6265328f6e51289765ac7851dedf551 737 Pfam PF00145 C-5 cytosine-specific DNA methylase 153 211 6.2E-5 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 TSH58p_06275 1d62aa79d3c6d49bbf6b4677f8a0387f 252 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 131 147 2.9E-9 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_06275 1d62aa79d3c6d49bbf6b4677f8a0387f 252 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 149 169 2.9E-9 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_06275 1d62aa79d3c6d49bbf6b4677f8a0387f 252 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 100 113 2.9E-9 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_06275 1d62aa79d3c6d49bbf6b4677f8a0387f 252 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 5 16 2.9E-9 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_06275 1d62aa79d3c6d49bbf6b4677f8a0387f 252 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 187 5.9E-30 T 14-10-2018 TSH58p_06275 1d62aa79d3c6d49bbf6b4677f8a0387f 252 SUPERFAMILY SSF56784 6 214 1.26E-48 T 14-10-2018 IPR036412 HAD-like superfamily TSH58p_06275 1d62aa79d3c6d49bbf6b4677f8a0387f 252 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 134 187 4.7E-12 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_06275 1d62aa79d3c6d49bbf6b4677f8a0387f 252 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 102 181 3.7E-7 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_06275 1d62aa79d3c6d49bbf6b4677f8a0387f 252 Gene3D G3DSA:3.40.50.1000 9 204 1.1E-48 T 14-10-2018 IPR023214 HAD superfamily TSH58p_06275 1d62aa79d3c6d49bbf6b4677f8a0387f 252 Gene3D G3DSA:1.10.150.240 20 86 1.1E-48 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 TSH58p_28565 4361f9ea1696ac7e02d549526a69dda0 136 Gene3D G3DSA:3.10.450.160 65 135 7.8E-11 T 14-10-2018 TSH58p_28565 4361f9ea1696ac7e02d549526a69dda0 136 Pfam PF11776 Nickel/cobalt transporter regulator 79 128 7.1E-19 T 14-10-2018 IPR024572 Nickel/cobalt homeostasis protein RcnB TSH58p_28565 4361f9ea1696ac7e02d549526a69dda0 136 ProDom PD456999 SIGNAL PRECURSOR TRANSMEMBRANE MEMBRANE YOHN INTEGRAL EXPORTED SIMILAR LIPOPROTEIN LIPOPROTEIN 74 132 2.0E-10 T 14-10-2018 IPR024572 Nickel/cobalt homeostasis protein RcnB TSH58p_15695 68f6cf8d5b8bdcd2771379431e1f3911 1021 SUPERFAMILY SSF55874 708 882 6.29E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_15695 68f6cf8d5b8bdcd2771379431e1f3911 1021 SMART SM00448 902 1011 1.3E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_15695 68f6cf8d5b8bdcd2771379431e1f3911 1021 PRINTS PR00344 Bacterial sensor protein C-terminal signature 827 837 1.2E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_15695 68f6cf8d5b8bdcd2771379431e1f3911 1021 PRINTS PR00344 Bacterial sensor protein C-terminal signature 864 877 1.2E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_15695 68f6cf8d5b8bdcd2771379431e1f3911 1021 PRINTS PR00344 Bacterial sensor protein C-terminal signature 809 823 1.2E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_15695 68f6cf8d5b8bdcd2771379431e1f3911 1021 PRINTS PR00344 Bacterial sensor protein C-terminal signature 840 858 1.2E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_15695 68f6cf8d5b8bdcd2771379431e1f3911 1021 SMART SM00388 651 718 0.0027 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_15695 68f6cf8d5b8bdcd2771379431e1f3911 1021 Gene3D G3DSA:3.30.565.10 719 889 1.2E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_15695 68f6cf8d5b8bdcd2771379431e1f3911 1021 Gene3D G3DSA:3.40.50.2300 893 1017 3.7E-30 T 14-10-2018 TSH58p_15695 68f6cf8d5b8bdcd2771379431e1f3911 1021 Gene3D G3DSA:1.10.287.130 643 716 3.9E-17 T 14-10-2018 TSH58p_15695 68f6cf8d5b8bdcd2771379431e1f3911 1021 Gene3D G3DSA:3.30.450.20 504 642 8.0E-15 T 14-10-2018 TSH58p_15695 68f6cf8d5b8bdcd2771379431e1f3911 1021 SUPERFAMILY SSF55785 367 490 4.51E-13 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_15695 68f6cf8d5b8bdcd2771379431e1f3911 1021 SUPERFAMILY SSF47384 645 715 3.92E-6 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_15695 68f6cf8d5b8bdcd2771379431e1f3911 1021 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 760 878 2.6E-15 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_15695 68f6cf8d5b8bdcd2771379431e1f3911 1021 SUPERFAMILY SSF52172 900 1015 9.68E-33 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_15695 68f6cf8d5b8bdcd2771379431e1f3911 1021 Pfam PF00072 Response regulator receiver domain 904 1012 1.4E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_15695 68f6cf8d5b8bdcd2771379431e1f3911 1021 Gene3D G3DSA:2.10.70.100 449 494 5.5E-7 T 14-10-2018 TSH58p_15695 68f6cf8d5b8bdcd2771379431e1f3911 1021 SUPERFAMILY SSF55785 488 624 8.38E-7 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_15695 68f6cf8d5b8bdcd2771379431e1f3911 1021 Gene3D G3DSA:3.30.450.20 374 442 1.1E-7 T 14-10-2018 TSH58p_15695 68f6cf8d5b8bdcd2771379431e1f3911 1021 SMART SM00387 759 880 3.2E-26 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_15695 68f6cf8d5b8bdcd2771379431e1f3911 1021 Pfam PF08448 PAS fold 519 631 1.7E-11 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_15695 68f6cf8d5b8bdcd2771379431e1f3911 1021 Gene3D G3DSA:3.30.450.20 51 199 2.0E-7 T 14-10-2018 TSH58p_21335 d12fce9078ba62204f28f16f8d9c7dde 325 Pfam PF02653 Branched-chain amino acid transport system / permease component 37 304 7.0E-44 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_01240 1d23db8008a4c7a72fa4fc2b69e82e77 323 Gene3D G3DSA:3.60.15.10 38 279 4.8E-43 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_01240 1d23db8008a4c7a72fa4fc2b69e82e77 323 TIGRFAM TIGR04559 SoxH_rel_PQQ_2: quinoprotein relay system zinc metallohydrolase 2 41 323 3.5E-116 T 14-10-2018 IPR030829 Quinoprotein relay system zinc metallohydrolase 2 TSH58p_01240 1d23db8008a4c7a72fa4fc2b69e82e77 323 SMART SM00849 68 252 3.5E-18 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_01240 1d23db8008a4c7a72fa4fc2b69e82e77 323 SUPERFAMILY SSF56281 21 304 1.37E-53 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_01240 1d23db8008a4c7a72fa4fc2b69e82e77 323 Pfam PF00753 Metallo-beta-lactamase superfamily 67 252 3.2E-17 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_23870 c20845b8b9e1e402c116fee552cf26fd 309 SUPERFAMILY SSF52768 3 307 2.01E-102 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily TSH58p_23870 c20845b8b9e1e402c116fee552cf26fd 309 PRINTS PR01270 Histone deacetylase superfamily signature 236 246 2.5E-16 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSH58p_23870 c20845b8b9e1e402c116fee552cf26fd 309 PRINTS PR01270 Histone deacetylase superfamily signature 121 144 2.5E-16 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSH58p_23870 c20845b8b9e1e402c116fee552cf26fd 309 PRINTS PR01270 Histone deacetylase superfamily signature 155 170 2.5E-16 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSH58p_23870 c20845b8b9e1e402c116fee552cf26fd 309 Gene3D G3DSA:3.40.800.20 1 308 6.3E-116 T 14-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSH58p_23870 c20845b8b9e1e402c116fee552cf26fd 309 Pfam PF00850 Histone deacetylase domain 20 305 9.2E-86 T 14-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSH58p_15210 107f6bb04eea9f2700258f5f83719cfb 84 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 3 76 24.27 T 14-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15210 107f6bb04eea9f2700258f5f83719cfb 84 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 3 74 8.5E-37 T 14-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15210 107f6bb04eea9f2700258f5f83719cfb 84 Gene3D G3DSA:2.40.50.140 1 83 9.5E-35 T 14-10-2018 TSH58p_15210 107f6bb04eea9f2700258f5f83719cfb 84 Pfam PF00366 Ribosomal protein S17 8 74 3.0E-32 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15210 107f6bb04eea9f2700258f5f83719cfb 84 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 1 74 1.0E-26 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15210 107f6bb04eea9f2700258f5f83719cfb 84 ProSitePatterns PS00056 Ribosomal protein S17 signature. 54 66 - T 14-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15210 107f6bb04eea9f2700258f5f83719cfb 84 PRINTS PR00973 Ribosomal protein S17 family signature 22 45 5.4E-13 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15210 107f6bb04eea9f2700258f5f83719cfb 84 PRINTS PR00973 Ribosomal protein S17 family signature 64 71 5.4E-13 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15210 107f6bb04eea9f2700258f5f83719cfb 84 PRINTS PR00973 Ribosomal protein S17 family signature 54 64 5.4E-13 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15210 107f6bb04eea9f2700258f5f83719cfb 84 SUPERFAMILY SSF50249 3 74 1.67E-31 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_31590 d9b39246be3b01174d4de36d9026b70c 922 Pfam PF12698 ABC-2 family transporter protein 583 912 4.3E-38 T 14-10-2018 TSH58p_31590 d9b39246be3b01174d4de36d9026b70c 922 SMART SM00382 307 498 5.2E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_31590 d9b39246be3b01174d4de36d9026b70c 922 SMART SM00382 43 231 1.7E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_31590 d9b39246be3b01174d4de36d9026b70c 922 Gene3D G3DSA:3.40.50.300 276 521 5.2E-64 T 14-10-2018 TSH58p_31590 d9b39246be3b01174d4de36d9026b70c 922 SUPERFAMILY SSF52540 20 246 1.11E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_31590 d9b39246be3b01174d4de36d9026b70c 922 Pfam PF00005 ABC transporter 299 442 3.0E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_31590 d9b39246be3b01174d4de36d9026b70c 922 Gene3D G3DSA:3.40.50.300 5 263 1.2E-58 T 14-10-2018 TSH58p_31590 d9b39246be3b01174d4de36d9026b70c 922 Pfam PF00005 ABC transporter 35 181 4.0E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_31590 d9b39246be3b01174d4de36d9026b70c 922 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_31590 d9b39246be3b01174d4de36d9026b70c 922 SUPERFAMILY SSF52540 276 504 1.22E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_20685 a49846b5d50be9dc3c4bcf13bc2ba169 480 SUPERFAMILY SSF53300 134 473 2.64E-18 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TSH58p_20685 a49846b5d50be9dc3c4bcf13bc2ba169 480 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 24 69 3.3E-13 T 14-10-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal TSH58p_28715 293dc59dec357807313939f854a3ed91 108 Pfam PF06844 Protein of unknown function (DUF1244) 27 92 4.1E-37 T 14-10-2018 IPR023163 SMc04008-like domain TSH58p_28715 293dc59dec357807313939f854a3ed91 108 Gene3D G3DSA:1.10.3340.10 1 100 6.1E-47 T 14-10-2018 IPR036810 SMc04008-like superfamily TSH58p_28715 293dc59dec357807313939f854a3ed91 108 SUPERFAMILY SSF158757 1 77 4.32E-37 T 14-10-2018 IPR036810 SMc04008-like superfamily TSH58p_04045 4c7711988117260e33a4069a83f75d35 145 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 20.374 T 14-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 TSH58p_04045 4c7711988117260e33a4069a83f75d35 145 Pfam PF01250 Ribosomal protein S6 4 92 4.9E-29 T 14-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_04045 4c7711988117260e33a4069a83f75d35 145 Gene3D G3DSA:3.30.70.60 1 101 1.2E-28 T 14-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 TSH58p_04045 4c7711988117260e33a4069a83f75d35 145 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 4.5E-24 T 14-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_04045 4c7711988117260e33a4069a83f75d35 145 SUPERFAMILY SSF54995 1 104 1.01E-32 T 14-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_20695 2801d01c433707a501547aef19bb19b8 188 Pfam PF07811 TadE-like protein 18 60 7.8E-7 T 14-10-2018 IPR012495 TadE-like TSH58p_16845 7f69d75d64fa7891f0cd7ddae2bb0f04 200 SUPERFAMILY SSF52172 5 147 2.85E-27 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_16845 7f69d75d64fa7891f0cd7ddae2bb0f04 200 SUPERFAMILY SSF46894 132 197 5.44E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_16845 7f69d75d64fa7891f0cd7ddae2bb0f04 200 Gene3D G3DSA:3.40.50.2300 1 130 2.5E-43 T 14-10-2018 TSH58p_16845 7f69d75d64fa7891f0cd7ddae2bb0f04 200 SMART SM00421 139 196 1.5E-21 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_16845 7f69d75d64fa7891f0cd7ddae2bb0f04 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 184 3.1E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_16845 7f69d75d64fa7891f0cd7ddae2bb0f04 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 142 156 3.1E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_16845 7f69d75d64fa7891f0cd7ddae2bb0f04 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 172 3.1E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_16845 7f69d75d64fa7891f0cd7ddae2bb0f04 200 Pfam PF00196 Bacterial regulatory proteins, luxR family 141 195 8.7E-21 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_16845 7f69d75d64fa7891f0cd7ddae2bb0f04 200 ProSitePatterns PS00622 LuxR-type HTH domain signature. 156 183 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_16845 7f69d75d64fa7891f0cd7ddae2bb0f04 200 Pfam PF00072 Response regulator receiver domain 7 115 2.1E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_16845 7f69d75d64fa7891f0cd7ddae2bb0f04 200 SMART SM00448 4 115 8.7E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_16845 7f69d75d64fa7891f0cd7ddae2bb0f04 200 Gene3D G3DSA:1.10.10.10 134 198 6.8E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_10890 28c369c70b2b1a78fd4c9cd330cfa962 644 SUPERFAMILY SSF53850 87 626 7.24E-70 T 14-10-2018 TSH58p_10890 28c369c70b2b1a78fd4c9cd330cfa962 644 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 110 516 7.9E-55 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain TSH58p_10890 28c369c70b2b1a78fd4c9cd330cfa962 644 Gene3D G3DSA:3.10.105.10 352 603 2.7E-33 T 14-10-2018 TSH58p_14750 263b1da524e1e2a6bc6f1d72fe9d65de 260 SUPERFAMILY SSF48371 85 255 6.91E-35 T 14-10-2018 IPR016024 Armadillo-type fold TSH58p_14750 263b1da524e1e2a6bc6f1d72fe9d65de 260 Gene3D G3DSA:1.25.40.290 141 256 1.6E-26 T 14-10-2018 TSH58p_32425 dd1a54bab17e151e40c947d188d4fdba 698 SUPERFAMILY SSF56935 38 698 2.41E-82 T 14-10-2018 TSH58p_32425 dd1a54bab17e151e40c947d188d4fdba 698 Pfam PF07715 TonB-dependent Receptor Plug Domain 66 164 8.2E-14 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain TSH58p_32425 dd1a54bab17e151e40c947d188d4fdba 698 Gene3D G3DSA:2.40.170.20 175 698 2.5E-57 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily TSH58p_32425 dd1a54bab17e151e40c947d188d4fdba 698 Pfam PF00593 TonB dependent receptor 233 697 6.8E-31 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel TSH58p_32425 dd1a54bab17e151e40c947d188d4fdba 698 Gene3D G3DSA:2.170.130.10 50 174 8.2E-17 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily TSH58p_30955 ff430a960405810e15a42ef96d8f4b05 281 Gene3D G3DSA:3.40.50.970 10 280 5.1E-87 T 14-10-2018 TSH58p_30955 ff430a960405810e15a42ef96d8f4b05 281 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 27 267 1.3E-40 T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TSH58p_30955 ff430a960405810e15a42ef96d8f4b05 281 SUPERFAMILY SSF52518 12 276 3.37E-81 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_23145 c174184badd20b001cd87f0ca9e2804d 666 SUPERFAMILY SSF55874 8 149 5.75E-6 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_15135 e63d3c8dbda13a9ab24ec50aa28f2885 237 Pfam PF01965 DJ-1/PfpI family 10 166 1.8E-26 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 TSH58p_15135 e63d3c8dbda13a9ab24ec50aa28f2885 237 SUPERFAMILY SSF52317 8 187 2.29E-48 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_15135 e63d3c8dbda13a9ab24ec50aa28f2885 237 Gene3D G3DSA:3.40.50.880 1 232 3.6E-72 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_18355 969ac3c4e047fa2d7e93c2a10d70e106 563 Gene3D G3DSA:2.150.10.10 181 391 4.1E-52 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_18355 969ac3c4e047fa2d7e93c2a10d70e106 563 Gene3D G3DSA:2.150.10.10 413 551 9.2E-17 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_18355 969ac3c4e047fa2d7e93c2a10d70e106 563 SUPERFAMILY SSF51120 406 528 2.49E-18 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_18355 969ac3c4e047fa2d7e93c2a10d70e106 563 SUPERFAMILY SSF55486 3 201 5.5E-39 T 14-10-2018 TSH58p_18355 969ac3c4e047fa2d7e93c2a10d70e106 563 Pfam PF08548 Peptidase M10 serralysin C terminal 200 300 2.9E-16 T 14-10-2018 IPR013858 Peptidase M10 serralysin, C-terminal GO:0005509|GO:0005615 TSH58p_18355 969ac3c4e047fa2d7e93c2a10d70e106 563 PRINTS PR00313 NodO calcium binding signature 302 310 1.1E-11 T 14-10-2018 TSH58p_18355 969ac3c4e047fa2d7e93c2a10d70e106 563 PRINTS PR00313 NodO calcium binding signature 462 471 1.1E-11 T 14-10-2018 TSH58p_18355 969ac3c4e047fa2d7e93c2a10d70e106 563 PRINTS PR00313 NodO calcium binding signature 444 452 1.1E-11 T 14-10-2018 TSH58p_18355 969ac3c4e047fa2d7e93c2a10d70e106 563 PRINTS PR00313 NodO calcium binding signature 281 292 1.1E-11 T 14-10-2018 TSH58p_18355 969ac3c4e047fa2d7e93c2a10d70e106 563 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 431 449 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site TSH58p_18355 969ac3c4e047fa2d7e93c2a10d70e106 563 SMART SM00235 17 203 0.0067 T 14-10-2018 IPR006026 Peptidase, metallopeptidase GO:0006508|GO:0008237|GO:0008270 TSH58p_18355 969ac3c4e047fa2d7e93c2a10d70e106 563 SUPERFAMILY SSF51120 208 364 3.01E-24 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal TSH58p_18355 969ac3c4e047fa2d7e93c2a10d70e106 563 Gene3D G3DSA:3.40.390.10 5 143 2.7E-23 T 14-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 TSH58p_18355 969ac3c4e047fa2d7e93c2a10d70e106 563 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 225 235 60.0 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18355 969ac3c4e047fa2d7e93c2a10d70e106 563 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 283 298 0.72 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18355 969ac3c4e047fa2d7e93c2a10d70e106 563 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 301 318 0.0023 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18355 969ac3c4e047fa2d7e93c2a10d70e106 563 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 425 442 4.2 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_18355 969ac3c4e047fa2d7e93c2a10d70e106 563 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 444 460 0.076 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TSH58p_29365 06e75642e0651fa500b8f392fad056c4 155 Pfam PF13673 Acetyltransferase (GNAT) domain 51 149 2.2E-9 T 14-10-2018 IPR000182 GNAT domain TSH58p_29365 06e75642e0651fa500b8f392fad056c4 155 Gene3D G3DSA:3.40.630.30 1 151 1.4E-23 T 14-10-2018 TSH58p_29365 06e75642e0651fa500b8f392fad056c4 155 SUPERFAMILY SSF55729 1 149 9.26E-21 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_12690 b4bd35dfaa0de72f08e5415bdf7a743d 306 SMART SM00448 6 118 3.3E-38 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_12690 b4bd35dfaa0de72f08e5415bdf7a743d 306 SUPERFAMILY SSF52172 4 129 1.71E-39 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_12690 b4bd35dfaa0de72f08e5415bdf7a743d 306 Gene3D G3DSA:3.30.70.270 126 300 4.2E-61 T 14-10-2018 TSH58p_12690 b4bd35dfaa0de72f08e5415bdf7a743d 306 SUPERFAMILY SSF55073 140 298 9.42E-51 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_12690 b4bd35dfaa0de72f08e5415bdf7a743d 306 SMART SM00267 124 300 1.8E-67 T 14-10-2018 IPR000160 GGDEF domain TSH58p_12690 b4bd35dfaa0de72f08e5415bdf7a743d 306 Pfam PF00072 Response regulator receiver domain 8 118 1.6E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_12690 b4bd35dfaa0de72f08e5415bdf7a743d 306 Pfam PF00990 Diguanylate cyclase, GGDEF domain 137 296 2.1E-50 T 14-10-2018 IPR000160 GGDEF domain TSH58p_12690 b4bd35dfaa0de72f08e5415bdf7a743d 306 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 132 297 7.1E-52 T 14-10-2018 IPR000160 GGDEF domain TSH58p_12690 b4bd35dfaa0de72f08e5415bdf7a743d 306 Gene3D G3DSA:3.40.50.2300 1 125 4.8E-37 T 14-10-2018 TSH58p_01905 23b4d209b9cb5a2ccab1d3c403845d0f 230 Gene3D G3DSA:1.10.10.60 44 88 2.5E-6 T 14-10-2018 TSH58p_01905 23b4d209b9cb5a2ccab1d3c403845d0f 230 SUPERFAMILY SSF88659 52 88 4.97E-5 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSH58p_20800 8aad4450e871c4ddd0dc5d3a3095677b 338 SUPERFAMILY SSF55781 20 167 4.8E-14 T 14-10-2018 TSH58p_20800 8aad4450e871c4ddd0dc5d3a3095677b 338 Gene3D G3DSA:3.30.450.40 3 163 8.4E-13 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_20800 8aad4450e871c4ddd0dc5d3a3095677b 338 Pfam PF00990 Diguanylate cyclase, GGDEF domain 175 334 1.0E-33 T 14-10-2018 IPR000160 GGDEF domain TSH58p_20800 8aad4450e871c4ddd0dc5d3a3095677b 338 SMART SM00065 18 164 9.8E-7 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_20800 8aad4450e871c4ddd0dc5d3a3095677b 338 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 170 334 1.0E-34 T 14-10-2018 IPR000160 GGDEF domain TSH58p_20800 8aad4450e871c4ddd0dc5d3a3095677b 338 Gene3D G3DSA:3.30.70.270 164 337 2.7E-44 T 14-10-2018 TSH58p_20800 8aad4450e871c4ddd0dc5d3a3095677b 338 SUPERFAMILY SSF55073 179 334 5.1E-36 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_20800 8aad4450e871c4ddd0dc5d3a3095677b 338 SMART SM00267 163 337 9.7E-37 T 14-10-2018 IPR000160 GGDEF domain TSH58p_20800 8aad4450e871c4ddd0dc5d3a3095677b 338 Pfam PF13185 GAF domain 71 154 8.8E-7 T 14-10-2018 IPR003018 GAF domain GO:0005515 TSH58p_04570 072c5d25ac2ea536694422d9c3252600 277 SUPERFAMILY SSF161098 7 262 6.17E-54 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_04570 072c5d25ac2ea536694422d9c3252600 277 Gene3D G3DSA:1.10.3720.10 11 267 5.9E-50 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_04570 072c5d25ac2ea536694422d9c3252600 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 266 2.1E-16 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_14805 b1ec49bf7445b2f0ab51e545ad3d35bd 187 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 146 162 - T 14-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 TSH58p_14805 b1ec49bf7445b2f0ab51e545ad3d35bd 187 Gene3D G3DSA:1.10.287.180 28 102 3.4E-28 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 TSH58p_14805 b1ec49bf7445b2f0ab51e545ad3d35bd 187 Pfam PF03449 Transcription elongation factor, N-terminal 30 100 2.8E-25 T 14-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 TSH58p_14805 b1ec49bf7445b2f0ab51e545ad3d35bd 187 PIRSF PIRSF006092 27 183 4.2E-46 T 14-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 TSH58p_14805 b1ec49bf7445b2f0ab51e545ad3d35bd 187 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 108 182 4.3E-23 T 14-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 TSH58p_14805 b1ec49bf7445b2f0ab51e545ad3d35bd 187 SUPERFAMILY SSF54534 107 182 2.22E-19 T 14-10-2018 TSH58p_14805 b1ec49bf7445b2f0ab51e545ad3d35bd 187 SUPERFAMILY SSF46557 29 103 3.79E-27 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 TSH58p_14805 b1ec49bf7445b2f0ab51e545ad3d35bd 187 Hamap MF_00105 Transcription elongation factor GreA [greA]. 28 181 26.273 T 14-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 TSH58p_14805 b1ec49bf7445b2f0ab51e545ad3d35bd 187 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 43 74 - T 14-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 TSH58p_14805 b1ec49bf7445b2f0ab51e545ad3d35bd 187 Gene3D G3DSA:3.10.50.30 105 184 3.6E-26 T 14-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 TSH58p_14805 b1ec49bf7445b2f0ab51e545ad3d35bd 187 TIGRFAM TIGR01461 greB: transcription elongation factor GreB 29 183 9.3E-68 T 14-10-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 TSH58p_14805 b1ec49bf7445b2f0ab51e545ad3d35bd 187 Hamap MF_00930 Transcription elongation factor GreB [greB]. 27 183 51.976 T 14-10-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 TSH58p_24940 7d0814cabc696271954824a6ded5960e 133 SUPERFAMILY SSF52172 1 129 7.12E-30 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_24940 7d0814cabc696271954824a6ded5960e 133 Gene3D G3DSA:3.40.50.12740 1 133 2.1E-30 T 14-10-2018 TSH58p_24940 7d0814cabc696271954824a6ded5960e 133 Pfam PF00072 Response regulator receiver domain 4 125 2.7E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_24940 7d0814cabc696271954824a6ded5960e 133 SMART SM00448 2 124 6.8E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_27160 75ef116012f4a7289f5802414c7ee1c3 310 Gene3D G3DSA:3.90.25.10 171 304 1.6E-88 T 14-10-2018 TSH58p_27160 75ef116012f4a7289f5802414c7ee1c3 310 Gene3D G3DSA:3.40.50.720 5 294 1.6E-88 T 14-10-2018 TSH58p_27160 75ef116012f4a7289f5802414c7ee1c3 310 SUPERFAMILY SSF51735 3 304 5.6E-84 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_27160 75ef116012f4a7289f5802414c7ee1c3 310 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 239 2.1E-55 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TSH58p_30310 29ba96c298099536468da5a1ac3eed79 119 SUPERFAMILY SSF46626 19 117 6.81E-35 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_30310 29ba96c298099536468da5a1ac3eed79 119 Gene3D G3DSA:1.10.760.10 6 118 1.8E-45 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_30310 29ba96c298099536468da5a1ac3eed79 119 PRINTS PR00604 Class IA and IB cytochrome C signature 109 117 1.8E-22 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_30310 29ba96c298099536468da5a1ac3eed79 119 PRINTS PR00604 Class IA and IB cytochrome C signature 31 38 1.8E-22 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_30310 29ba96c298099536468da5a1ac3eed79 119 PRINTS PR00604 Class IA and IB cytochrome C signature 44 59 1.8E-22 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_30310 29ba96c298099536468da5a1ac3eed79 119 PRINTS PR00604 Class IA and IB cytochrome C signature 73 89 1.8E-22 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_30310 29ba96c298099536468da5a1ac3eed79 119 PRINTS PR00604 Class IA and IB cytochrome C signature 92 102 1.8E-22 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_30310 29ba96c298099536468da5a1ac3eed79 119 Pfam PF00034 Cytochrome c 22 117 7.2E-10 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_28270 e2d29f335ddc4556ac71225c0be75f79 480 SUPERFAMILY SSF109998 48 214 1.29E-34 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily TSH58p_28270 e2d29f335ddc4556ac71225c0be75f79 480 SUPERFAMILY SSF54534 318 413 4.58E-12 T 14-10-2018 TSH58p_28270 e2d29f335ddc4556ac71225c0be75f79 480 Gene3D G3DSA:1.10.4030.30 48 190 6.2E-67 T 14-10-2018 TSH58p_28270 e2d29f335ddc4556ac71225c0be75f79 480 SUPERFAMILY SSF54534 190 291 8.5E-23 T 14-10-2018 TSH58p_28270 e2d29f335ddc4556ac71225c0be75f79 480 Pfam PF09312 SurA N-terminal domain 47 160 4.5E-20 T 14-10-2018 IPR015391 SurA N-terminal TSH58p_28270 e2d29f335ddc4556ac71225c0be75f79 480 Pfam PF00639 PPIC-type PPIASE domain 202 287 5.5E-19 T 14-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 TSH58p_28270 e2d29f335ddc4556ac71225c0be75f79 480 Gene3D G3DSA:3.10.50.40 191 290 6.2E-67 T 14-10-2018 TSH58p_28270 e2d29f335ddc4556ac71225c0be75f79 480 Gene3D G3DSA:3.10.50.40 315 415 6.7E-9 T 14-10-2018 TSH58p_27355 06cf642687782a9806408433ef3eec7c 207 Pfam PF09335 SNARE associated Golgi protein 40 162 1.4E-19 T 14-10-2018 IPR032816 SNARE associated Golgi protein TSH58p_13420 65fe51f5db56605311af3159d15b2d51 462 Gene3D G3DSA:3.40.220.10 6 134 8.8E-32 T 14-10-2018 TSH58p_13420 65fe51f5db56605311af3159d15b2d51 462 Gene3D G3DSA:3.40.630.10 137 461 2.6E-121 T 14-10-2018 TSH58p_13420 65fe51f5db56605311af3159d15b2d51 462 PRINTS PR00481 Cytosol aminopeptidase signature 284 305 1.0E-40 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TSH58p_13420 65fe51f5db56605311af3159d15b2d51 462 PRINTS PR00481 Cytosol aminopeptidase signature 306 326 1.0E-40 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TSH58p_13420 65fe51f5db56605311af3159d15b2d51 462 PRINTS PR00481 Cytosol aminopeptidase signature 334 349 1.0E-40 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TSH58p_13420 65fe51f5db56605311af3159d15b2d51 462 PRINTS PR00481 Cytosol aminopeptidase signature 225 242 1.0E-40 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TSH58p_13420 65fe51f5db56605311af3159d15b2d51 462 PRINTS PR00481 Cytosol aminopeptidase signature 247 268 1.0E-40 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TSH58p_13420 65fe51f5db56605311af3159d15b2d51 462 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 151 435 6.7E-103 T 14-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 TSH58p_13420 65fe51f5db56605311af3159d15b2d51 462 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 310 317 - T 14-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 TSH58p_13420 65fe51f5db56605311af3159d15b2d51 462 SUPERFAMILY SSF53187 146 458 1.98E-103 T 14-10-2018 TSH58p_04950 633c3d0bdd118471747a156bd4fc104a 272 TIGRFAM TIGR02017 hutG_amidohyd: N-formylglutamate deformylase 4 259 8.0E-94 T 14-10-2018 IPR010247 N-formylglutamate deformylase TSH58p_04950 633c3d0bdd118471747a156bd4fc104a 272 SUPERFAMILY SSF53187 3 261 1.13E-76 T 14-10-2018 TSH58p_04950 633c3d0bdd118471747a156bd4fc104a 272 Pfam PF05013 N-formylglutamate amidohydrolase 12 228 2.1E-64 T 14-10-2018 IPR007709 N-formylglutamate amidohydrolase TSH58p_04950 633c3d0bdd118471747a156bd4fc104a 272 Gene3D G3DSA:3.40.630.40 1 262 3.2E-74 T 14-10-2018 TSH58p_28845 f5841056240f47ffead59e1808565728 178 Pfam PF01799 [2Fe-2S] binding domain 91 163 5.4E-32 T 14-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 TSH58p_28845 f5841056240f47ffead59e1808565728 178 Gene3D G3DSA:3.10.20.30 10 92 2.6E-31 T 14-10-2018 IPR012675 Beta-grasp domain superfamily TSH58p_28845 f5841056240f47ffead59e1808565728 178 SUPERFAMILY SSF47741 102 170 3.27E-31 T 14-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily TSH58p_28845 f5841056240f47ffead59e1808565728 178 SUPERFAMILY SSF54292 17 105 1.17E-26 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TSH58p_28845 f5841056240f47ffead59e1808565728 178 Gene3D G3DSA:1.10.150.120 93 177 1.8E-33 T 14-10-2018 TSH58p_28845 f5841056240f47ffead59e1808565728 178 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 24 79 1.1E-7 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 TSH58p_28845 f5841056240f47ffead59e1808565728 178 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 57 65 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 TSH58p_26495 d424ea2e3aa4f580d585041de4e7b51c 488 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 42 388 4.0E-39 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TSH58p_26495 d424ea2e3aa4f580d585041de4e7b51c 488 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 411 458 1.9E-5 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TSH58p_26495 d424ea2e3aa4f580d585041de4e7b51c 488 SUPERFAMILY SSF56601 35 460 9.05E-55 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TSH58p_26495 d424ea2e3aa4f580d585041de4e7b51c 488 Gene3D G3DSA:3.50.80.20 96 171 4.1E-15 T 14-10-2018 TSH58p_26495 d424ea2e3aa4f580d585041de4e7b51c 488 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 68 87 1.5E-11 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TSH58p_26495 d424ea2e3aa4f580d585041de4e7b51c 488 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 373 387 1.5E-11 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TSH58p_26495 d424ea2e3aa4f580d585041de4e7b51c 488 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 358 372 1.5E-11 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TSH58p_26495 d424ea2e3aa4f580d585041de4e7b51c 488 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 298 320 1.5E-11 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TSH58p_26495 d424ea2e3aa4f580d585041de4e7b51c 488 Gene3D G3DSA:3.40.710.10 39 95 5.7E-6 T 14-10-2018 TSH58p_26495 d424ea2e3aa4f580d585041de4e7b51c 488 Gene3D G3DSA:3.40.710.10 277 465 1.2E-27 T 14-10-2018 TSH58p_25795 8a92a54579108473ee9df773356beca3 118 Pfam PF03413 Peptidase propeptide and YPEB domain 46 103 6.8E-10 T 14-10-2018 IPR025711 PepSY domain TSH58p_25795 8a92a54579108473ee9df773356beca3 118 Gene3D G3DSA:3.10.450.40 38 105 8.1E-8 T 14-10-2018 TSH58p_06755 010021422cd13d3f4af18ee6d0c24c2c 140 Pfam PF01814 Hemerythrin HHE cation binding domain 25 108 1.9E-7 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 TSH58p_06755 010021422cd13d3f4af18ee6d0c24c2c 140 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 15 135 4.7E-20 T 14-10-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 TSH58p_06755 010021422cd13d3f4af18ee6d0c24c2c 140 Gene3D G3DSA:1.20.120.50 11 139 7.0E-20 T 14-10-2018 IPR035938 Hemerythrin-like superfamily TSH58p_06755 010021422cd13d3f4af18ee6d0c24c2c 140 SUPERFAMILY SSF47188 10 135 2.75E-25 T 14-10-2018 IPR035938 Hemerythrin-like superfamily TSH58p_07680 c8a8bce51a3a45f4e0c5fc5f95034e2e 154 TIGRFAM TIGR02935 TIGR02935: probable nitrogen fixation protein 14 152 1.1E-65 T 14-10-2018 IPR004952 Uncharacterised protein family UPF0460 TSH58p_07680 c8a8bce51a3a45f4e0c5fc5f95034e2e 154 Gene3D G3DSA:1.10.3100.20 2 154 1.7E-64 T 14-10-2018 TSH58p_07680 c8a8bce51a3a45f4e0c5fc5f95034e2e 154 PIRSF PIRSF005788 1 154 4.5E-68 T 14-10-2018 IPR004952 Uncharacterised protein family UPF0460 TSH58p_07680 c8a8bce51a3a45f4e0c5fc5f95034e2e 154 Pfam PF03270 Protein of unknown function, DUF269 33 152 7.3E-54 T 14-10-2018 IPR004952 Uncharacterised protein family UPF0460 TSH58p_31605 2e0b51408f7643f9568c17f39f840f85 166 SUPERFAMILY SSF144064 5 157 1.11E-41 T 14-10-2018 TSH58p_31605 2e0b51408f7643f9568c17f39f840f85 166 TIGRFAM TIGR04108 HutX: putative heme utilization carrier protein HutX 2 154 3.5E-55 T 14-10-2018 IPR010413 Heme utilization carrier protein HutX-like TSH58p_31605 2e0b51408f7643f9568c17f39f840f85 166 PIRSF PIRSF030840 1 160 5.4E-53 T 14-10-2018 IPR010413 Heme utilization carrier protein HutX-like TSH58p_31605 2e0b51408f7643f9568c17f39f840f85 166 Gene3D G3DSA:3.40.1570.10 1 161 4.0E-51 T 14-10-2018 TSH58p_31605 2e0b51408f7643f9568c17f39f840f85 166 Pfam PF06228 Haem utilisation ChuX/HutX 17 154 1.2E-29 T 14-10-2018 IPR010413 Heme utilization carrier protein HutX-like TSH58p_08810 1d46e5521361eecd41fcc75e53683cf9 237 SMART SM00850 138 236 1.3E-29 T 14-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 TSH58p_08810 1d46e5521361eecd41fcc75e53683cf9 237 Pfam PF04397 LytTr DNA-binding domain 140 235 2.0E-22 T 14-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 TSH58p_08810 1d46e5521361eecd41fcc75e53683cf9 237 Gene3D G3DSA:3.30.450.20 1 97 8.1E-9 T 14-10-2018 TSH58p_08810 1d46e5521361eecd41fcc75e53683cf9 237 Pfam PF08448 PAS fold 6 95 3.8E-8 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_08810 1d46e5521361eecd41fcc75e53683cf9 237 Gene3D G3DSA:2.40.50.40 130 198 1.5E-12 T 14-10-2018 TSH58p_08810 1d46e5521361eecd41fcc75e53683cf9 237 SUPERFAMILY SSF55785 3 91 3.06E-9 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_03300 e88e653d0083cad95dbf318438213ead 264 Pfam PF11306 Protein of unknown function (DUF3108) 15 247 5.5E-17 T 14-10-2018 IPR021457 Protein of unknown function DUF3108 TSH58p_30980 849e5368f6aff2c7e5126aa62dd75b95 761 Gene3D G3DSA:2.40.170.20 208 761 2.4E-69 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily TSH58p_30980 849e5368f6aff2c7e5126aa62dd75b95 761 Gene3D G3DSA:2.170.130.10 59 199 1.1E-12 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily TSH58p_30980 849e5368f6aff2c7e5126aa62dd75b95 761 Pfam PF00593 TonB dependent receptor 311 759 5.5E-45 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel TSH58p_30980 849e5368f6aff2c7e5126aa62dd75b95 761 Pfam PF07715 TonB-dependent Receptor Plug Domain 77 187 1.4E-9 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain TSH58p_30980 849e5368f6aff2c7e5126aa62dd75b95 761 SUPERFAMILY SSF56935 48 761 2.08E-97 T 14-10-2018 TSH58p_08915 49a307ac67657dc744655db4d8cd840d 292 Pfam PF00588 SpoU rRNA Methylase family 143 285 7.6E-31 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TSH58p_08915 49a307ac67657dc744655db4d8cd840d 292 SUPERFAMILY SSF75217 137 288 3.35E-32 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases TSH58p_08915 49a307ac67657dc744655db4d8cd840d 292 SUPERFAMILY SSF55315 47 121 1.18E-8 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like TSH58p_08915 49a307ac67657dc744655db4d8cd840d 292 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 51 122 1.3E-8 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 TSH58p_08915 49a307ac67657dc744655db4d8cd840d 292 Gene3D G3DSA:3.40.1280.10 129 291 1.6E-36 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TSH58p_08915 49a307ac67657dc744655db4d8cd840d 292 SMART SM00967 50 125 2.6E-9 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 TSH58p_18765 bd8af870c035f72c3554ca32009b1f97 97 Gene3D G3DSA:3.30.70.100 1 94 1.6E-27 T 14-10-2018 TSH58p_18765 bd8af870c035f72c3554ca32009b1f97 97 ProSitePatterns PS00151 Acylphosphatase signature 2. 38 54 - T 14-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TSH58p_18765 bd8af870c035f72c3554ca32009b1f97 97 Pfam PF00708 Acylphosphatase 12 92 3.0E-22 T 14-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TSH58p_18765 bd8af870c035f72c3554ca32009b1f97 97 SUPERFAMILY SSF54975 8 94 5.89E-26 T 14-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TSH58p_18765 bd8af870c035f72c3554ca32009b1f97 97 PRINTS PR00112 Acylphosphatase signature 9 24 2.3E-7 T 14-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TSH58p_18765 bd8af870c035f72c3554ca32009b1f97 97 PRINTS PR00112 Acylphosphatase signature 30 55 2.3E-7 T 14-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TSH58p_16485 2ae98c3c0b54c967ee8e837bf7598566 463 SMART SM00283 28 289 7.7E-29 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_16485 2ae98c3c0b54c967ee8e837bf7598566 463 SUPERFAMILY SSF58104 12 290 1.83E-50 T 14-10-2018 TSH58p_16485 2ae98c3c0b54c967ee8e837bf7598566 463 Gene3D G3DSA:1.10.287.950 7 295 2.1E-48 T 14-10-2018 TSH58p_16485 2ae98c3c0b54c967ee8e837bf7598566 463 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 109 252 8.8E-27 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_12225 e754b3a6bb9ba0dd06284602f2d577fb 992 TIGRFAM TIGR02786 addB_alphas: double-strand break repair protein AddB 8 984 0.0 T 14-10-2018 IPR014153 Double-strand break repair protein AddB TSH58p_12225 e754b3a6bb9ba0dd06284602f2d577fb 992 SUPERFAMILY SSF52540 324 673 6.05E-35 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_12225 e754b3a6bb9ba0dd06284602f2d577fb 992 Pfam PF12705 PD-(D/E)XK nuclease superfamily 720 962 1.3E-22 T 14-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type TSH58p_26770 ce245186a84d564d89212c25712ea2b9 223 Gene3D G3DSA:1.10.3720.10 3 216 1.9E-47 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_26770 ce245186a84d564d89212c25712ea2b9 223 SUPERFAMILY SSF161098 14 204 3.4E-39 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_26770 ce245186a84d564d89212c25712ea2b9 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 205 1.9E-11 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_26770 ce245186a84d564d89212c25712ea2b9 223 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 111 2.7E-28 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 TSH58p_25030 bc41568c0136efcbdc30d658743d948c 743 Gene3D G3DSA:3.40.50.300 401 550 4.2E-112 T 14-10-2018 TSH58p_25030 bc41568c0136efcbdc30d658743d948c 743 Gene3D G3DSA:3.40.50.300 246 400 4.2E-112 T 14-10-2018 TSH58p_25030 bc41568c0136efcbdc30d658743d948c 743 Pfam PF12513 Mitochondrial degradasome RNA helicase subunit C terminal 669 712 6.4E-9 T 14-10-2018 IPR022192 Mitochondrial degradasome RNA helicase subunit, C-terminal domain GO:0016817 TSH58p_25030 bc41568c0136efcbdc30d658743d948c 743 SMART SM00487 245 411 0.0041 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSH58p_25030 bc41568c0136efcbdc30d658743d948c 743 SUPERFAMILY SSF52540 257 526 1.03E-32 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_25030 bc41568c0136efcbdc30d658743d948c 743 Gene3D G3DSA:1.20.272.40 241 619 4.2E-112 T 14-10-2018 TSH58p_25030 bc41568c0136efcbdc30d658743d948c 743 SMART SM00490 432 521 3.7E-19 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_25030 bc41568c0136efcbdc30d658743d948c 743 Pfam PF00271 Helicase conserved C-terminal domain 416 521 2.4E-10 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_20935 3cf576d1f13e863eb92771ea8dc35aa1 401 Gene3D G3DSA:3.40.50.10540 3 395 2.3E-113 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily TSH58p_20935 3cf576d1f13e863eb92771ea8dc35aa1 401 Pfam PF02515 CoA-transferase family III 4 378 1.2E-114 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 TSH58p_20935 3cf576d1f13e863eb92771ea8dc35aa1 401 SUPERFAMILY SSF89796 2 400 8.63E-117 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily TSH58p_20935 3cf576d1f13e863eb92771ea8dc35aa1 401 Gene3D G3DSA:3.30.1540.10 234 324 2.3E-113 T 14-10-2018 TSH58p_05465 29f362d7454b3a1255b86225dd7183c9 516 Pfam PF03023 MviN-like protein 27 469 1.5E-119 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSH58p_05465 29f362d7454b3a1255b86225dd7183c9 516 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 1 465 19.705 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSH58p_05465 29f362d7454b3a1255b86225dd7183c9 516 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 2 499 4.1E-138 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSH58p_05465 29f362d7454b3a1255b86225dd7183c9 516 PIRSF PIRSF002869 1 512 1.0E-156 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSH58p_05465 29f362d7454b3a1255b86225dd7183c9 516 PRINTS PR01806 Virulence factor MviN signature 257 283 3.0E-75 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSH58p_05465 29f362d7454b3a1255b86225dd7183c9 516 PRINTS PR01806 Virulence factor MviN signature 155 176 3.0E-75 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSH58p_05465 29f362d7454b3a1255b86225dd7183c9 516 PRINTS PR01806 Virulence factor MviN signature 355 374 3.0E-75 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSH58p_05465 29f362d7454b3a1255b86225dd7183c9 516 PRINTS PR01806 Virulence factor MviN signature 50 66 3.0E-75 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSH58p_05465 29f362d7454b3a1255b86225dd7183c9 516 PRINTS PR01806 Virulence factor MviN signature 131 155 3.0E-75 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSH58p_05465 29f362d7454b3a1255b86225dd7183c9 516 PRINTS PR01806 Virulence factor MviN signature 31 50 3.0E-75 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSH58p_05465 29f362d7454b3a1255b86225dd7183c9 516 PRINTS PR01806 Virulence factor MviN signature 407 424 3.0E-75 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSH58p_10415 20f915e90d96fd24e589a46979c8d29a 417 Gene3D G3DSA:3.40.640.10 61 313 2.1E-113 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_10415 20f915e90d96fd24e589a46979c8d29a 417 Pfam PF00155 Aminotransferase class I and II 50 412 5.6E-42 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSH58p_10415 20f915e90d96fd24e589a46979c8d29a 417 SUPERFAMILY SSF53383 19 416 1.0E-80 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_10415 20f915e90d96fd24e589a46979c8d29a 417 Gene3D G3DSA:3.90.1150.10 31 405 2.1E-113 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_21085 c09ba6e3847a4abb42e3895ef54ea8c8 316 Pfam PF03466 LysR substrate binding domain 95 299 1.0E-25 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_21085 c09ba6e3847a4abb42e3895ef54ea8c8 316 SUPERFAMILY SSF53850 97 300 2.02E-27 T 14-10-2018 TSH58p_21085 c09ba6e3847a4abb42e3895ef54ea8c8 316 SUPERFAMILY SSF46785 10 95 1.36E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_21085 c09ba6e3847a4abb42e3895ef54ea8c8 316 Gene3D G3DSA:3.40.190.290 99 303 1.4E-14 T 14-10-2018 TSH58p_21085 c09ba6e3847a4abb42e3895ef54ea8c8 316 Gene3D G3DSA:1.10.10.10 9 93 1.6E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_21085 c09ba6e3847a4abb42e3895ef54ea8c8 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 70 1.7E-14 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_04565 adc9bb8ea2613924eef2da235cd7c042 338 Hamap MF_01841 Agmatine deiminase [aguA]. 2 337 49.196 T 14-10-2018 IPR017754 Agmatine deiminase GO:0009446|GO:0047632 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 TSH58p_04565 adc9bb8ea2613924eef2da235cd7c042 338 SUPERFAMILY SSF55909 2 337 4.46E-128 T 14-10-2018 TSH58p_04565 adc9bb8ea2613924eef2da235cd7c042 338 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 11 336 1.2E-120 T 14-10-2018 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 TSH58p_04565 adc9bb8ea2613924eef2da235cd7c042 338 Gene3D G3DSA:3.75.10.10 1 337 3.4E-131 T 14-10-2018 TSH58p_08695 acc3583b8163ac4a5dad71ca52f0d8e7 431 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 429 1.3E-150 T 14-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSH58p_08695 acc3583b8163ac4a5dad71ca52f0d8e7 431 Gene3D G3DSA:1.20.200.10 93 347 2.6E-90 T 14-10-2018 TSH58p_08695 acc3583b8163ac4a5dad71ca52f0d8e7 431 Gene3D G3DSA:1.10.40.30 349 428 7.2E-28 T 14-10-2018 TSH58p_08695 acc3583b8163ac4a5dad71ca52f0d8e7 431 ProSitePatterns PS00163 Fumarate lyases signature. 261 270 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 TSH58p_08695 acc3583b8163ac4a5dad71ca52f0d8e7 431 Pfam PF00206 Lyase 7 284 1.7E-54 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal TSH58p_08695 acc3583b8163ac4a5dad71ca52f0d8e7 431 SUPERFAMILY SSF48557 3 429 7.7E-133 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 TSH58p_08695 acc3583b8163ac4a5dad71ca52f0d8e7 431 SMART SM00998 349 429 6.3E-37 T 14-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSH58p_08695 acc3583b8163ac4a5dad71ca52f0d8e7 431 Gene3D G3DSA:1.10.275.10 1 92 6.8E-35 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal TSH58p_08695 acc3583b8163ac4a5dad71ca52f0d8e7 431 PRINTS PR00145 Argininosuccinate lyase family signature 216 240 5.5E-5 T 14-10-2018 TSH58p_08695 acc3583b8163ac4a5dad71ca52f0d8e7 431 PRINTS PR00145 Argininosuccinate lyase family signature 261 277 5.5E-5 T 14-10-2018 TSH58p_08695 acc3583b8163ac4a5dad71ca52f0d8e7 431 PRINTS PR00145 Argininosuccinate lyase family signature 128 148 5.5E-5 T 14-10-2018 TSH58p_08695 acc3583b8163ac4a5dad71ca52f0d8e7 431 Pfam PF10397 Adenylosuccinate lyase C-terminus 350 428 9.8E-25 T 14-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSH58p_08695 acc3583b8163ac4a5dad71ca52f0d8e7 431 PRINTS PR00149 Fumarate lyase superfamily signature 261 277 3.6E-24 T 14-10-2018 IPR000362 Fumarate lyase family TSH58p_08695 acc3583b8163ac4a5dad71ca52f0d8e7 431 PRINTS PR00149 Fumarate lyase superfamily signature 88 106 3.6E-24 T 14-10-2018 IPR000362 Fumarate lyase family TSH58p_08695 acc3583b8163ac4a5dad71ca52f0d8e7 431 PRINTS PR00149 Fumarate lyase superfamily signature 216 243 3.6E-24 T 14-10-2018 IPR000362 Fumarate lyase family TSH58p_08695 acc3583b8163ac4a5dad71ca52f0d8e7 431 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 3.6E-24 T 14-10-2018 IPR000362 Fumarate lyase family TSH58p_30415 f0d39b47a3f37b2587306101025124b0 393 Gene3D G3DSA:3.30.9.10 101 327 1.4E-88 T 14-10-2018 TSH58p_30415 f0d39b47a3f37b2587306101025124b0 393 SUPERFAMILY SSF51905 17 383 3.37E-50 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_30415 f0d39b47a3f37b2587306101025124b0 393 Gene3D G3DSA:3.50.50.60 18 366 1.4E-88 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_30415 f0d39b47a3f37b2587306101025124b0 393 Pfam PF01266 FAD dependent oxidoreductase 18 362 1.8E-52 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TSH58p_30415 f0d39b47a3f37b2587306101025124b0 393 SUPERFAMILY SSF54373 236 325 2.09E-5 T 14-10-2018 TSH58p_22055 535b5d11d5ff04cf6b04fa6ecb888cd7 76 Pfam PF11390 NADH-dependant formate dehydrogenase delta subunit FdsD 7 65 3.5E-27 T 14-10-2018 IPR021074 Formate dehydrogenase, delta subunit TSH58p_02860 94363775c62c1e58fd28af79d8b44aed 335 Gene3D G3DSA:3.90.25.10 172 310 5.5E-96 T 14-10-2018 TSH58p_02860 94363775c62c1e58fd28af79d8b44aed 335 PRINTS PR01713 Nucleotide sugar epimerase signature 277 294 1.4E-5 T 14-10-2018 TSH58p_02860 94363775c62c1e58fd28af79d8b44aed 335 PRINTS PR01713 Nucleotide sugar epimerase signature 235 250 1.4E-5 T 14-10-2018 TSH58p_02860 94363775c62c1e58fd28af79d8b44aed 335 PRINTS PR01713 Nucleotide sugar epimerase signature 212 227 1.4E-5 T 14-10-2018 TSH58p_02860 94363775c62c1e58fd28af79d8b44aed 335 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 241 4.5E-60 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TSH58p_02860 94363775c62c1e58fd28af79d8b44aed 335 SUPERFAMILY SSF51735 1 314 2.69E-98 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_02860 94363775c62c1e58fd28af79d8b44aed 335 Gene3D G3DSA:3.40.50.720 4 298 5.5E-96 T 14-10-2018 TSH58p_01855 1d1c12ca69e7e049ff46b7e14781899c 296 Pfam PF13354 Beta-lactamase enzyme family 58 264 4.6E-49 T 14-10-2018 TSH58p_01855 1d1c12ca69e7e049ff46b7e14781899c 296 Gene3D G3DSA:3.40.710.10 33 296 6.6E-88 T 14-10-2018 TSH58p_01855 1d1c12ca69e7e049ff46b7e14781899c 296 ProSitePatterns PS00146 Beta-lactamase class-A active site. 71 86 - T 14-10-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 TSH58p_01855 1d1c12ca69e7e049ff46b7e14781899c 296 PRINTS PR00118 Beta-lactamase class A signature 227 242 3.2E-60 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 TSH58p_01855 1d1c12ca69e7e049ff46b7e14781899c 296 PRINTS PR00118 Beta-lactamase class A signature 38 62 3.2E-60 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 TSH58p_01855 1d1c12ca69e7e049ff46b7e14781899c 296 PRINTS PR00118 Beta-lactamase class A signature 69 86 3.2E-60 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 TSH58p_01855 1d1c12ca69e7e049ff46b7e14781899c 296 PRINTS PR00118 Beta-lactamase class A signature 112 137 3.2E-60 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 TSH58p_01855 1d1c12ca69e7e049ff46b7e14781899c 296 PRINTS PR00118 Beta-lactamase class A signature 174 199 3.2E-60 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 TSH58p_01855 1d1c12ca69e7e049ff46b7e14781899c 296 PRINTS PR00118 Beta-lactamase class A signature 148 172 3.2E-60 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 TSH58p_01855 1d1c12ca69e7e049ff46b7e14781899c 296 PRINTS PR00118 Beta-lactamase class A signature 210 225 3.2E-60 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 TSH58p_01855 1d1c12ca69e7e049ff46b7e14781899c 296 SUPERFAMILY SSF56601 34 292 3.1E-80 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TSH58p_01010 94d1574c92f01da3dc6ca825371c3380 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 252 3.3E-63 T 14-10-2018 TSH58p_01010 94d1574c92f01da3dc6ca825371c3380 256 Gene3D G3DSA:3.40.50.720 2 254 2.7E-81 T 14-10-2018 TSH58p_01010 94d1574c92f01da3dc6ca825371c3380 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_01010 94d1574c92f01da3dc6ca825371c3380 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 8.1E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_01010 94d1574c92f01da3dc6ca825371c3380 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 8.1E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_01010 94d1574c92f01da3dc6ca825371c3380 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 8.1E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_01010 94d1574c92f01da3dc6ca825371c3380 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 14 192 4.4E-5 T 14-10-2018 TSH58p_01010 94d1574c92f01da3dc6ca825371c3380 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 4.2E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_01010 94d1574c92f01da3dc6ca825371c3380 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 4.2E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_01010 94d1574c92f01da3dc6ca825371c3380 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 4.2E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_01010 94d1574c92f01da3dc6ca825371c3380 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 4.2E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_01010 94d1574c92f01da3dc6ca825371c3380 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 4.2E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_01010 94d1574c92f01da3dc6ca825371c3380 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 4.2E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_01010 94d1574c92f01da3dc6ca825371c3380 256 SUPERFAMILY SSF51735 9 252 4.71E-79 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_08255 91da723dda4fb815422d2064ce5abbc8 233 Pfam PF00005 ABC transporter 17 161 4.4E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_08255 91da723dda4fb815422d2064ce5abbc8 233 Gene3D G3DSA:3.40.50.300 1 233 1.6E-57 T 14-10-2018 TSH58p_08255 91da723dda4fb815422d2064ce5abbc8 233 SMART SM00382 26 210 0.0066 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_08255 91da723dda4fb815422d2064ce5abbc8 233 SUPERFAMILY SSF52540 2 230 3.22E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_10830 bfb666c726e7463ce3e0b9fa1a9a51fc 264 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 262 9.2E-57 T 14-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 TSH58p_10830 bfb666c726e7463ce3e0b9fa1a9a51fc 264 SUPERFAMILY SSF56219 1 263 6.02E-70 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TSH58p_10830 bfb666c726e7463ce3e0b9fa1a9a51fc 264 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 261 1.1E-58 T 14-10-2018 TSH58p_10830 bfb666c726e7463ce3e0b9fa1a9a51fc 264 Gene3D G3DSA:3.60.10.10 1 263 5.3E-60 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TSH58p_10830 bfb666c726e7463ce3e0b9fa1a9a51fc 264 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 27 36 - T 14-10-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 TSH58p_10830 bfb666c726e7463ce3e0b9fa1a9a51fc 264 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 255 1.0E-23 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase TSH58p_01980 f6fdff70d63dadca3f28a4d2b23d3da9 718 Pfam PF13229 Right handed beta helix region 457 552 9.2E-10 T 14-10-2018 IPR039448 Right handed beta helix domain TSH58p_01980 f6fdff70d63dadca3f28a4d2b23d3da9 718 Pfam PF13229 Right handed beta helix region 570 712 6.3E-6 T 14-10-2018 IPR039448 Right handed beta helix domain TSH58p_01980 f6fdff70d63dadca3f28a4d2b23d3da9 718 Gene3D G3DSA:2.60.60.40 72 187 3.5E-10 T 14-10-2018 TSH58p_01980 f6fdff70d63dadca3f28a4d2b23d3da9 718 Gene3D G3DSA:2.60.60.40 208 322 5.6E-9 T 14-10-2018 TSH58p_01980 f6fdff70d63dadca3f28a4d2b23d3da9 718 SUPERFAMILY SSF51126 369 667 1.44E-33 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor TSH58p_01980 f6fdff70d63dadca3f28a4d2b23d3da9 718 Gene3D G3DSA:2.160.20.10 364 665 5.3E-31 T 14-10-2018 IPR012334 Pectin lyase fold TSH58p_01980 f6fdff70d63dadca3f28a4d2b23d3da9 718 SMART SM00710 489 511 0.62 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_01980 f6fdff70d63dadca3f28a4d2b23d3da9 718 SMART SM00710 276 321 5200.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_01980 f6fdff70d63dadca3f28a4d2b23d3da9 718 SMART SM00710 465 487 700.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_01980 f6fdff70d63dadca3f28a4d2b23d3da9 718 SMART SM00710 513 535 460.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_01980 f6fdff70d63dadca3f28a4d2b23d3da9 718 SMART SM00710 674 697 350.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_01980 f6fdff70d63dadca3f28a4d2b23d3da9 718 SMART SM00710 599 620 3300.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_01980 f6fdff70d63dadca3f28a4d2b23d3da9 718 SMART SM00710 621 643 41.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_01980 f6fdff70d63dadca3f28a4d2b23d3da9 718 Pfam PF16841 Ca-dependent carbohydrate-binding module xylan-binding 75 166 8.9E-31 T 14-10-2018 IPR031768 Carbohydrate binding module, xylan-binding domain MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSH58p_01980 f6fdff70d63dadca3f28a4d2b23d3da9 718 Pfam PF16841 Ca-dependent carbohydrate-binding module xylan-binding 210 301 4.2E-31 T 14-10-2018 IPR031768 Carbohydrate binding module, xylan-binding domain MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSH58p_11800 23ae503f3d3a4d0c6e58ecdc7d2ae739 144 Gene3D G3DSA:3.30.1490.190 85 138 1.3E-16 T 14-10-2018 TSH58p_11800 23ae503f3d3a4d0c6e58ecdc7d2ae739 144 SUPERFAMILY SSF46785 4 132 5.94E-36 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_11800 23ae503f3d3a4d0c6e58ecdc7d2ae739 144 Gene3D G3DSA:1.10.10.10 1 83 2.2E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_11800 23ae503f3d3a4d0c6e58ecdc7d2ae739 144 Pfam PF01475 Ferric uptake regulator family 11 130 8.6E-38 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 TSH58p_18090 e194d384aa47e74fbc44ff5cf7a97617 182 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 41 173 2.3E-11 T 14-10-2018 IPR009936 Protein of unknown function DUF1468 TSH58p_30565 8623a8a65e672c3a0c31ba0c2f3919b1 418 SUPERFAMILY SSF53383 34 401 6.53E-120 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_30565 8623a8a65e672c3a0c31ba0c2f3919b1 418 PIRSF PIRSF001434 1 402 3.9E-144 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TSH58p_30565 8623a8a65e672c3a0c31ba0c2f3919b1 418 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 207 221 - T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TSH58p_30565 8623a8a65e672c3a0c31ba0c2f3919b1 418 Gene3D G3DSA:3.90.1150.10 267 408 9.5E-51 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_30565 8623a8a65e672c3a0c31ba0c2f3919b1 418 Gene3D G3DSA:3.40.640.10 13 266 6.8E-93 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_30565 8623a8a65e672c3a0c31ba0c2f3919b1 418 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 16 398 7.0E-136 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TSH58p_06785 bbf91953b12e11617f830b3c2ed2badf 154 Pfam PF14489 QueF-like protein 58 136 6.4E-32 T 14-10-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 TSH58p_06785 bbf91953b12e11617f830b3c2ed2badf 154 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 23 133 1.3E-44 T 14-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 TSH58p_06785 bbf91953b12e11617f830b3c2ed2badf 154 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 154 68.47 T 14-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 TSH58p_06785 bbf91953b12e11617f830b3c2ed2badf 154 SUPERFAMILY SSF55620 24 133 7.19E-26 T 14-10-2018 TSH58p_06785 bbf91953b12e11617f830b3c2ed2badf 154 Gene3D G3DSA:3.30.1130.10 19 140 3.5E-40 T 14-10-2018 TSH58p_18335 b156265de82dae5ea24bb583643393f3 415 Pfam PF12000 Gkycosyl transferase family 4 group 26 191 5.6E-64 T 14-10-2018 IPR022623 Domain of unknown function DUF3495 TSH58p_18335 b156265de82dae5ea24bb583643393f3 415 SUPERFAMILY SSF53756 16 391 1.1E-42 T 14-10-2018 TSH58p_18335 b156265de82dae5ea24bb583643393f3 415 Gene3D G3DSA:3.40.50.2000 187 382 9.3E-35 T 14-10-2018 TSH58p_18335 b156265de82dae5ea24bb583643393f3 415 Pfam PF00534 Glycosyl transferases group 1 211 380 7.2E-16 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 TSH58p_18335 b156265de82dae5ea24bb583643393f3 415 Gene3D G3DSA:3.40.50.2000 18 391 9.3E-35 T 14-10-2018 TSH58p_32040 765db197d60fd95c1d2abf6d2172f813 224 Pfam PF13628 Domain of unknown function (DUF4142) 44 199 3.7E-20 T 14-10-2018 IPR025419 Domain of unknown function DUF4142 TSH58p_32040 765db197d60fd95c1d2abf6d2172f813 224 Gene3D G3DSA:1.20.1260.10 35 204 2.6E-7 T 14-10-2018 IPR012347 Ferritin-like TSH58p_32130 0a2f4c843293a95a3ca830400038febf 342 Gene3D G3DSA:3.40.718.10 1 338 3.0E-121 T 14-10-2018 TSH58p_32130 0a2f4c843293a95a3ca830400038febf 342 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 5 335 1.2E-104 T 14-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 TSH58p_32130 0a2f4c843293a95a3ca830400038febf 342 SUPERFAMILY SSF53659 3 338 1.22E-98 T 14-10-2018 TSH58p_32130 0a2f4c843293a95a3ca830400038febf 342 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 38 331 1.1E-100 T 14-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 TSH58p_24880 7b803c73e59a5dc8a2679cdb1443ddf3 402 Gene3D G3DSA:3.40.50.2000 178 352 3.5E-52 T 14-10-2018 TSH58p_24880 7b803c73e59a5dc8a2679cdb1443ddf3 402 Pfam PF13439 Glycosyltransferase Family 4 68 178 2.0E-8 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TSH58p_24880 7b803c73e59a5dc8a2679cdb1443ddf3 402 Gene3D G3DSA:3.40.50.2000 78 369 3.5E-52 T 14-10-2018 TSH58p_24880 7b803c73e59a5dc8a2679cdb1443ddf3 402 SUPERFAMILY SSF53756 19 372 1.05E-59 T 14-10-2018 TSH58p_24880 7b803c73e59a5dc8a2679cdb1443ddf3 402 Pfam PF00534 Glycosyl transferases group 1 199 349 4.0E-28 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 TSH58p_11315 232828da160e7392b5cc8a6174338c79 170 SUPERFAMILY SSF55729 17 161 1.38E-26 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_11315 232828da160e7392b5cc8a6174338c79 170 Pfam PF00583 Acetyltransferase (GNAT) family 34 141 4.3E-14 T 14-10-2018 IPR000182 GNAT domain TSH58p_11315 232828da160e7392b5cc8a6174338c79 170 Gene3D G3DSA:3.40.630.30 19 169 2.2E-33 T 14-10-2018 TSH58p_17005 3509adf3a468d975e59303d4c2b97387 263 Gene3D G3DSA:3.90.226.10 11 263 9.8E-75 T 14-10-2018 TSH58p_17005 3509adf3a468d975e59303d4c2b97387 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 20 261 5.2E-54 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TSH58p_17005 3509adf3a468d975e59303d4c2b97387 263 SUPERFAMILY SSF52096 15 262 4.78E-75 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_29560 2dbfb3c036920437005ea6f01e091cbc 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 63 73 2.7E-29 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_29560 2dbfb3c036920437005ea6f01e091cbc 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 11 33 2.7E-29 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_29560 2dbfb3c036920437005ea6f01e091cbc 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 109 117 2.7E-29 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_29560 2dbfb3c036920437005ea6f01e091cbc 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 231 252 2.7E-29 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_29560 2dbfb3c036920437005ea6f01e091cbc 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 266 284 2.7E-29 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_29560 2dbfb3c036920437005ea6f01e091cbc 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 132 144 2.7E-29 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_29560 2dbfb3c036920437005ea6f01e091cbc 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 147 171 2.7E-29 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSH58p_29560 2dbfb3c036920437005ea6f01e091cbc 309 SUPERFAMILY SSF51905 7 304 7.78E-43 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_29560 2dbfb3c036920437005ea6f01e091cbc 309 Gene3D G3DSA:3.50.50.60 11 298 6.5E-82 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_29560 2dbfb3c036920437005ea6f01e091cbc 309 Gene3D G3DSA:3.50.50.60 122 235 6.5E-82 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_29560 2dbfb3c036920437005ea6f01e091cbc 309 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 151 169 3.1E-23 T 14-10-2018 TSH58p_29560 2dbfb3c036920437005ea6f01e091cbc 309 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 3.1E-23 T 14-10-2018 TSH58p_29560 2dbfb3c036920437005ea6f01e091cbc 309 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 3.1E-23 T 14-10-2018 TSH58p_29560 2dbfb3c036920437005ea6f01e091cbc 309 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 278 3.1E-23 T 14-10-2018 TSH58p_29560 2dbfb3c036920437005ea6f01e091cbc 309 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 229 245 3.1E-23 T 14-10-2018 TSH58p_29560 2dbfb3c036920437005ea6f01e091cbc 309 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 12 291 4.4E-28 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSH58p_11240 4d6a4290bb9a74b055409a545f386801 300 SUPERFAMILY SSF46689 16 67 1.26E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_11240 4d6a4290bb9a74b055409a545f386801 300 Pfam PF12833 Helix-turn-helix domain 39 115 5.0E-18 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TSH58p_11240 4d6a4290bb9a74b055409a545f386801 300 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 259 265 - T 14-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 TSH58p_11240 4d6a4290bb9a74b055409a545f386801 300 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 209 288 1.4E-30 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 TSH58p_11240 4d6a4290bb9a74b055409a545f386801 300 Gene3D G3DSA:3.30.160.70 114 195 8.0E-15 T 14-10-2018 TSH58p_11240 4d6a4290bb9a74b055409a545f386801 300 SUPERFAMILY SSF46767 208 289 7.98E-29 T 14-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 TSH58p_11240 4d6a4290bb9a74b055409a545f386801 300 Gene3D G3DSA:1.10.10.10 206 290 1.8E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_11240 4d6a4290bb9a74b055409a545f386801 300 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 211 289 4.3E-28 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 TSH58p_11240 4d6a4290bb9a74b055409a545f386801 300 SUPERFAMILY SSF53155 121 192 2.94E-17 T 14-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 TSH58p_11240 4d6a4290bb9a74b055409a545f386801 300 SMART SM00342 33 115 3.0E-16 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TSH58p_11240 4d6a4290bb9a74b055409a545f386801 300 Gene3D G3DSA:1.10.10.60 17 113 4.0E-20 T 14-10-2018 TSH58p_29190 dfb5e23a7fad05750162c9b15a363e80 350 TIGRFAM TIGR03586 PseI: pseudaminic acid synthase 18 340 1.0E-146 T 14-10-2018 IPR020030 Pseudaminic acid biosynthesis, PseI KEGG: 00520+2.5.1.97|MetaCyc: PWY-6143 TSH58p_29190 dfb5e23a7fad05750162c9b15a363e80 350 SUPERFAMILY SSF51569 5 297 1.22E-86 T 14-10-2018 TSH58p_29190 dfb5e23a7fad05750162c9b15a363e80 350 Pfam PF03102 NeuB family 38 273 3.1E-88 T 14-10-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 TSH58p_29190 dfb5e23a7fad05750162c9b15a363e80 350 Gene3D G3DSA:3.20.20.70 4 273 1.9E-94 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_29190 dfb5e23a7fad05750162c9b15a363e80 350 SMART SM00858 288 346 2.5E-13 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 TSH58p_29190 dfb5e23a7fad05750162c9b15a363e80 350 SUPERFAMILY SSF51269 287 346 1.88E-15 T 14-10-2018 IPR036732 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily Reactome: R-HSA-4085001 TSH58p_29190 dfb5e23a7fad05750162c9b15a363e80 350 Pfam PF08666 SAF domain 289 345 1.6E-11 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 TSH58p_29190 dfb5e23a7fad05750162c9b15a363e80 350 Gene3D G3DSA:3.90.1210.10 289 349 1.2E-17 T 14-10-2018 TSH58p_13505 c16b4c1decc603a7a29e9daadf7419c1 98 Gene3D G3DSA:2.30.30.110 1 98 7.1E-26 T 14-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor TSH58p_13505 c16b4c1decc603a7a29e9daadf7419c1 98 SUPERFAMILY SSF50118 2 95 1.18E-20 T 14-10-2018 TSH58p_13505 c16b4c1decc603a7a29e9daadf7419c1 98 ProDom PD012578 PLASMID TOXIN CCDB CYTOTOXIC LETB POST-SEGREGATION SYSTEM CCDB-LIKE GYRASE FUSED-CCDB 15 95 4.0E-8 T 14-10-2018 IPR002712 Toxin CcdB GO:0006276|GO:0008657 TSH58p_13505 c16b4c1decc603a7a29e9daadf7419c1 98 Pfam PF01845 CcdB protein 3 96 2.0E-25 T 14-10-2018 IPR002712 Toxin CcdB GO:0006276|GO:0008657 TSH58p_04775 a355d669f100c66458193c861251e738 95 Pfam PF12838 4Fe-4S dicluster domain 41 87 2.9E-7 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_04775 a355d669f100c66458193c861251e738 95 SUPERFAMILY SSF54862 40 93 1.67E-13 T 14-10-2018 TSH58p_04775 a355d669f100c66458193c861251e738 95 Gene3D G3DSA:3.30.70.20 31 92 3.0E-11 T 14-10-2018 TSH58p_04775 a355d669f100c66458193c861251e738 95 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 73 84 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_05060 3f3546bb7b692301ea6c63e0e184b259 76 Pfam PF09723 Zinc ribbon domain 1 38 5.4E-14 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain TSH58p_05060 3f3546bb7b692301ea6c63e0e184b259 76 SMART SM00834 1 40 4.0E-14 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain TSH58p_05060 3f3546bb7b692301ea6c63e0e184b259 76 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 44 3.0E-14 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain TSH58p_22480 d62d1cfc359cabcf1ba883c0cbcc2292 217 Gene3D G3DSA:1.10.10.10 93 190 9.0E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_22480 d62d1cfc359cabcf1ba883c0cbcc2292 217 Pfam PF04079 Segregation and condensation complex subunit ScpB 26 179 1.6E-47 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 TSH58p_22480 d62d1cfc359cabcf1ba883c0cbcc2292 217 Gene3D G3DSA:1.10.10.10 16 92 2.4E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_22480 d62d1cfc359cabcf1ba883c0cbcc2292 217 PIRSF PIRSF019345 8 213 1.5E-48 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 TSH58p_22480 d62d1cfc359cabcf1ba883c0cbcc2292 217 SUPERFAMILY SSF46785 22 92 1.5E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_22480 d62d1cfc359cabcf1ba883c0cbcc2292 217 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 27 183 1.1E-30 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 TSH58p_22480 d62d1cfc359cabcf1ba883c0cbcc2292 217 SUPERFAMILY SSF46785 96 171 4.16E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_02180 c0c65146ac734f2055045f7ea6b79ba1 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 3.3E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_02180 c0c65146ac734f2055045f7ea6b79ba1 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.4E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_02180 c0c65146ac734f2055045f7ea6b79ba1 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 1.4E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_02180 c0c65146ac734f2055045f7ea6b79ba1 190 SUPERFAMILY SSF46689 4 73 2.05E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_02180 c0c65146ac734f2055045f7ea6b79ba1 190 Gene3D G3DSA:1.10.357.10 1 189 1.8E-50 T 14-10-2018 TSH58p_26950 a00fd9a9c0a7e5e56413f3a923e89d72 556 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 69 475 3.4E-63 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 TSH58p_26950 a00fd9a9c0a7e5e56413f3a923e89d72 556 Pfam PF00474 Sodium:solute symporter family 69 475 5.0E-114 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 TSH58p_26950 a00fd9a9c0a7e5e56413f3a923e89d72 556 Gene3D G3DSA:1.20.1730.10 35 552 7.0E-63 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily TSH58p_26950 a00fd9a9c0a7e5e56413f3a923e89d72 556 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 184 209 - T 14-10-2018 IPR018212 Sodium/solute symporter, conserved site TSH58p_16175 7fa443e022511464a667d74c6ddb17f1 395 SUPERFAMILY SSF58113 246 379 1.09E-5 T 14-10-2018 TSH58p_04170 2a1cd586190713b0d24064f0a432480e 237 SUPERFAMILY SSF52317 1 194 1.63E-43 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_04170 2a1cd586190713b0d24064f0a432480e 237 Pfam PF00117 Glutamine amidotransferase class-I 20 180 2.2E-20 T 14-10-2018 IPR017926 Glutamine amidotransferase TSH58p_04170 2a1cd586190713b0d24064f0a432480e 237 Gene3D G3DSA:3.40.50.880 1 236 5.4E-57 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_21370 1d82b141c0966a0659204647583012ca 348 Pfam PF03466 LysR substrate binding domain 103 311 5.5E-37 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_21370 1d82b141c0966a0659204647583012ca 348 Gene3D G3DSA:1.10.10.10 15 103 1.0E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_21370 1d82b141c0966a0659204647583012ca 348 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 54 4.3E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_21370 1d82b141c0966a0659204647583012ca 348 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 44 4.3E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_21370 1d82b141c0966a0659204647583012ca 348 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 54 65 4.3E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_21370 1d82b141c0966a0659204647583012ca 348 SUPERFAMILY SSF53850 104 313 3.38E-35 T 14-10-2018 TSH58p_21370 1d82b141c0966a0659204647583012ca 348 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 18 76 3.3E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_21370 1d82b141c0966a0659204647583012ca 348 Gene3D G3DSA:3.40.190.10 181 284 1.7E-40 T 14-10-2018 TSH58p_21370 1d82b141c0966a0659204647583012ca 348 Gene3D G3DSA:3.40.190.10 108 301 1.7E-40 T 14-10-2018 TSH58p_21370 1d82b141c0966a0659204647583012ca 348 SUPERFAMILY SSF46785 14 125 1.14E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_23130 979cca6116ab6c41871b2511d0de8063 155 Pfam PF10027 Predicted integral membrane protein (DUF2269) 5 153 1.1E-60 T 14-10-2018 IPR018729 Protein of unknown function DUF2269, transmembrane TSH58p_24610 fb5a06918d2696c13fb20d7e395b3eb3 348 Gene3D G3DSA:3.40.190.10 31 326 1.1E-115 T 14-10-2018 TSH58p_24610 fb5a06918d2696c13fb20d7e395b3eb3 348 Gene3D G3DSA:3.40.190.10 130 332 1.1E-115 T 14-10-2018 TSH58p_24610 fb5a06918d2696c13fb20d7e395b3eb3 348 SUPERFAMILY SSF53850 28 345 2.81E-66 T 14-10-2018 TSH58p_24610 fb5a06918d2696c13fb20d7e395b3eb3 348 Pfam PF13416 Bacterial extracellular solute-binding protein 63 312 2.9E-42 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSH58p_30640 d088f690f7d8e5883669f62ae5b116b9 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.1E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30640 d088f690f7d8e5883669f62ae5b116b9 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.1E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30640 d088f690f7d8e5883669f62ae5b116b9 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.1E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30640 d088f690f7d8e5883669f62ae5b116b9 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 243 1.9E-71 T 14-10-2018 TSH58p_30640 d088f690f7d8e5883669f62ae5b116b9 252 SUPERFAMILY SSF51735 4 243 2.94E-84 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_30640 d088f690f7d8e5883669f62ae5b116b9 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_30640 d088f690f7d8e5883669f62ae5b116b9 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.3E-47 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30640 d088f690f7d8e5883669f62ae5b116b9 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 1.3E-47 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30640 d088f690f7d8e5883669f62ae5b116b9 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 1.3E-47 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30640 d088f690f7d8e5883669f62ae5b116b9 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.3E-47 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30640 d088f690f7d8e5883669f62ae5b116b9 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.3E-47 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30640 d088f690f7d8e5883669f62ae5b116b9 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.3E-47 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_30640 d088f690f7d8e5883669f62ae5b116b9 252 Gene3D G3DSA:3.40.50.720 1 247 1.5E-85 T 14-10-2018 TSH58p_30640 d088f690f7d8e5883669f62ae5b116b9 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 183 9.7E-5 T 14-10-2018 TSH58p_30235 f6c31a64ed6cead9a3e1d05421cd6159 393 Gene3D G3DSA:2.40.420.20 305 372 9.7E-94 T 14-10-2018 TSH58p_30235 f6c31a64ed6cead9a3e1d05421cd6159 393 Gene3D G3DSA:2.40.30.170 57 304 9.7E-94 T 14-10-2018 TSH58p_30235 f6c31a64ed6cead9a3e1d05421cd6159 393 Gene3D G3DSA:1.10.287.470 105 178 9.7E-94 T 14-10-2018 TSH58p_30235 f6c31a64ed6cead9a3e1d05421cd6159 393 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 46 375 9.2E-82 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 TSH58p_30235 f6c31a64ed6cead9a3e1d05421cd6159 393 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 72 294 1.8E-18 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain TSH58p_30235 f6c31a64ed6cead9a3e1d05421cd6159 393 Gene3D G3DSA:2.40.50.100 70 215 9.7E-94 T 14-10-2018 TSH58p_30235 f6c31a64ed6cead9a3e1d05421cd6159 393 SUPERFAMILY SSF111369 60 298 3.01E-64 T 14-10-2018 TSH58p_01625 f79ac676ac1cbddf53ee7ab892849c9c 427 SUPERFAMILY SSF52151 1 336 3.92E-23 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TSH58p_01625 f79ac676ac1cbddf53ee7ab892849c9c 427 Pfam PF01734 Patatin-like phospholipase 9 275 1.7E-8 T 14-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 TSH58p_01625 f79ac676ac1cbddf53ee7ab892849c9c 427 Gene3D G3DSA:3.40.1090.10 1 96 4.7E-7 T 14-10-2018 TSH58p_00335 86cb5f7d039af94b934f2ee03d7fa187 783 Pfam PF13641 Glycosyltransferase like family 2 473 703 9.1E-18 T 14-10-2018 TSH58p_00335 86cb5f7d039af94b934f2ee03d7fa187 783 SUPERFAMILY SSF53448 471 726 6.28E-46 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_00335 86cb5f7d039af94b934f2ee03d7fa187 783 Gene3D G3DSA:3.90.550.10 468 707 6.7E-44 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_21640 dfa7e842a00446a528803dab2bc3c3d0 313 Gene3D G3DSA:3.90.320.10 4 187 6.2E-23 T 14-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal TSH58p_21640 dfa7e842a00446a528803dab2bc3c3d0 313 SUPERFAMILY SSF52980 9 182 1.34E-17 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TSH58p_21640 dfa7e842a00446a528803dab2bc3c3d0 313 Pfam PF09588 YqaJ-like viral recombinase domain 10 140 8.6E-10 T 14-10-2018 IPR019080 YqaJ viral recombinase TSH58p_09460 5b172372958bb7bc35ba39475d4b8fd4 384 Pfam PF03969 AFG1-like ATPase 8 380 4.6E-124 T 14-10-2018 IPR005654 ATPase, AFG1-like GO:0005524 TSH58p_09460 5b172372958bb7bc35ba39475d4b8fd4 384 Gene3D G3DSA:3.40.50.300 50 199 3.5E-18 T 14-10-2018 TSH58p_09460 5b172372958bb7bc35ba39475d4b8fd4 384 SUPERFAMILY SSF52540 69 213 6.08E-13 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_10280 f14ed91bb7d31ce74216f51d492e3ea8 740 Pfam PF00905 Penicillin binding protein transpeptidase domain 394 623 6.2E-30 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 TSH58p_10280 f14ed91bb7d31ce74216f51d492e3ea8 740 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 148 659 6.8E-186 T 14-10-2018 TSH58p_10280 f14ed91bb7d31ce74216f51d492e3ea8 740 Gene3D G3DSA:1.10.3810.10 127 324 2.6E-74 T 14-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_10280 f14ed91bb7d31ce74216f51d492e3ea8 740 Pfam PF00912 Transglycosylase 141 307 4.9E-64 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_10280 f14ed91bb7d31ce74216f51d492e3ea8 740 Gene3D G3DSA:3.40.710.10 330 678 6.0E-111 T 14-10-2018 TSH58p_10280 f14ed91bb7d31ce74216f51d492e3ea8 740 SUPERFAMILY SSF56601 289 672 1.09E-120 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TSH58p_10280 f14ed91bb7d31ce74216f51d492e3ea8 740 SUPERFAMILY SSF53955 123 329 3.09E-74 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily TSH58p_16705 c9c757578c55767fadcddad124c684ee 345 Gene3D G3DSA:3.40.50.2300 9 136 5.3E-16 T 14-10-2018 TSH58p_16705 c9c757578c55767fadcddad124c684ee 345 Pfam PF00072 Response regulator receiver domain 13 124 1.8E-11 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_16705 c9c757578c55767fadcddad124c684ee 345 SUPERFAMILY SSF52172 13 132 1.85E-16 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_16705 c9c757578c55767fadcddad124c684ee 345 SMART SM00448 9 125 3.5E-4 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_12950 ae718975b642a20cd288817501940c33 160 SUPERFAMILY SSF54211 6 124 1.54E-25 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSH58p_12950 ae718975b642a20cd288817501940c33 160 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 5 123 16.164 T 14-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 TSH58p_12950 ae718975b642a20cd288817501940c33 160 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 12 98 5.0E-4 T 14-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 TSH58p_12950 ae718975b642a20cd288817501940c33 160 Gene3D G3DSA:3.30.230.10 6 129 1.8E-24 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSH58p_12950 ae718975b642a20cd288817501940c33 160 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 62 76 - T 14-10-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 TSH58p_12950 ae718975b642a20cd288817501940c33 160 Pfam PF00825 Ribonuclease P 7 120 1.6E-23 T 14-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 TSH58p_12950 ae718975b642a20cd288817501940c33 160 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 10 111 8.7E-14 T 14-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 TSH58p_09945 c690ad1486dd204850d1e6fc6b371781 94 Gene3D G3DSA:3.30.70.1060 1 93 1.7E-34 T 14-10-2018 TSH58p_09945 c690ad1486dd204850d1e6fc6b371781 94 SUPERFAMILY SSF54909 1 90 4.56E-24 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel TSH58p_09945 c690ad1486dd204850d1e6fc6b371781 94 Pfam PF03795 YCII-related domain 1 88 1.6E-22 T 14-10-2018 IPR005545 YCII-related TSH58p_06575 24f56b491a2a6445e29042a21fa9e3d5 265 SMART SM00382 31 234 1.2E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_06575 24f56b491a2a6445e29042a21fa9e3d5 265 Pfam PF00005 ABC transporter 22 177 8.3E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_06575 24f56b491a2a6445e29042a21fa9e3d5 265 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_06575 24f56b491a2a6445e29042a21fa9e3d5 265 SUPERFAMILY SSF52540 2 232 1.13E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_06575 24f56b491a2a6445e29042a21fa9e3d5 265 Gene3D G3DSA:3.40.50.300 1 242 1.5E-55 T 14-10-2018 TSH58p_05075 fb3f2c38ee6418c5fae791c5030b9ff1 149 SMART SM00116 13 65 2.0E-8 T 14-10-2018 IPR000644 CBS domain TSH58p_05075 fb3f2c38ee6418c5fae791c5030b9ff1 149 SMART SM00116 83 130 1.0E-9 T 14-10-2018 IPR000644 CBS domain TSH58p_05075 fb3f2c38ee6418c5fae791c5030b9ff1 149 SUPERFAMILY SSF54631 1 129 9.22E-31 T 14-10-2018 TSH58p_05075 fb3f2c38ee6418c5fae791c5030b9ff1 149 Pfam PF00571 CBS domain 79 128 1.5E-12 T 14-10-2018 IPR000644 CBS domain TSH58p_05075 fb3f2c38ee6418c5fae791c5030b9ff1 149 Pfam PF00571 CBS domain 4 65 3.0E-10 T 14-10-2018 IPR000644 CBS domain TSH58p_05075 fb3f2c38ee6418c5fae791c5030b9ff1 149 Gene3D G3DSA:3.10.580.10 1 141 3.2E-37 T 14-10-2018 TSH58p_30230 939f5640961ebf476de5d9646f9843f3 283 Gene3D G3DSA:3.40.50.1820 2 276 3.6E-59 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_30230 939f5640961ebf476de5d9646f9843f3 283 SUPERFAMILY SSF53474 17 271 6.72E-48 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_30230 939f5640961ebf476de5d9646f9843f3 283 Pfam PF07859 alpha/beta hydrolase fold 50 253 2.0E-49 T 14-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 TSH58p_24035 726d9d6636937601444158b441e9815f 1146 Pfam PF02514 CobN/Magnesium Chelatase 714 1132 3.1E-160 T 14-10-2018 IPR003672 CobN/magnesium chelatase GO:0009058 TSH58p_24035 726d9d6636937601444158b441e9815f 1146 Pfam PF02514 CobN/Magnesium Chelatase 144 703 5.1E-157 T 14-10-2018 IPR003672 CobN/magnesium chelatase GO:0009058 TSH58p_07105 f2593b0fc5d39a87cde1e08b982d9744 169 Pfam PF02627 Carboxymuconolactone decarboxylase family 74 153 2.6E-17 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TSH58p_07105 f2593b0fc5d39a87cde1e08b982d9744 169 SUPERFAMILY SSF69118 41 162 2.75E-29 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TSH58p_07105 f2593b0fc5d39a87cde1e08b982d9744 169 Gene3D G3DSA:1.20.1290.10 42 165 1.2E-28 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TSH58p_18150 0b4e5497ad0e19a3cb1e9e9cb57de214 787 SUPERFAMILY SSF53756 24 376 4.29E-27 T 14-10-2018 TSH58p_18150 0b4e5497ad0e19a3cb1e9e9cb57de214 787 Gene3D G3DSA:3.40.50.2000 137 373 4.1E-19 T 14-10-2018 TSH58p_18150 0b4e5497ad0e19a3cb1e9e9cb57de214 787 Gene3D G3DSA:3.40.50.2000 173 358 4.1E-19 T 14-10-2018 TSH58p_18150 0b4e5497ad0e19a3cb1e9e9cb57de214 787 Pfam PF13692 Glycosyl transferases group 1 195 343 5.6E-10 T 14-10-2018 TSH58p_17890 fdebf32f1711d48b34b481178565034b 301 Gene3D G3DSA:3.40.50.620 7 211 6.5E-61 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_17890 fdebf32f1711d48b34b481178565034b 301 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 8 301 9.8E-158 T 14-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 TSH58p_17890 fdebf32f1711d48b34b481178565034b 301 Hamap MF_00064 Sulfate adenylyltransferase subunit 2 [cysD]. 3 301 58.403 T 14-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 TSH58p_17890 fdebf32f1711d48b34b481178565034b 301 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 28 255 1.1E-61 T 14-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 TSH58p_17890 fdebf32f1711d48b34b481178565034b 301 PIRSF PIRSF002936 1 301 2.4E-145 T 14-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 TSH58p_17890 fdebf32f1711d48b34b481178565034b 301 SUPERFAMILY SSF52402 7 209 1.05E-70 T 14-10-2018 TSH58p_15795 f2490440ba21c630c579b09531e26a9c 115 SUPERFAMILY SSF55298 2 114 1.49E-34 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TSH58p_15795 f2490440ba21c630c579b09531e26a9c 115 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 91 109 - T 14-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 TSH58p_15795 f2490440ba21c630c579b09531e26a9c 115 Gene3D G3DSA:3.30.1330.40 1 115 7.5E-43 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TSH58p_15795 f2490440ba21c630c579b09531e26a9c 115 Pfam PF01042 Endoribonuclease L-PSP 11 114 6.0E-26 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 TSH58p_07455 a960dc0188ba751b942315784838f32e 345 SUPERFAMILY SSF53955 28 141 1.05E-9 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily TSH58p_07455 a960dc0188ba751b942315784838f32e 345 Gene3D G3DSA:1.10.530.10 16 220 4.1E-56 T 14-10-2018 TSH58p_24905 4ea7bbc7fbd45f8eced3c3ff96e83838 519 SUPERFAMILY SSF56801 4 518 1.1E-158 T 14-10-2018 TSH58p_24905 4ea7bbc7fbd45f8eced3c3ff96e83838 519 Pfam PF00501 AMP-binding enzyme 10 426 6.3E-112 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_24905 4ea7bbc7fbd45f8eced3c3ff96e83838 519 Gene3D G3DSA:3.40.50.12780 1 418 5.4E-124 T 14-10-2018 TSH58p_24905 4ea7bbc7fbd45f8eced3c3ff96e83838 519 Gene3D G3DSA:3.30.300.30 420 519 1.5E-28 T 14-10-2018 TSH58p_24905 4ea7bbc7fbd45f8eced3c3ff96e83838 519 PRINTS PR00154 AMP-binding signature 168 179 5.0E-5 T 14-10-2018 IPR020459 AMP-binding TSH58p_24905 4ea7bbc7fbd45f8eced3c3ff96e83838 519 PRINTS PR00154 AMP-binding signature 180 188 5.0E-5 T 14-10-2018 IPR020459 AMP-binding TSH58p_24905 4ea7bbc7fbd45f8eced3c3ff96e83838 519 Pfam PF13193 AMP-binding enzyme C-terminal domain 434 509 8.9E-20 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSH58p_24905 4ea7bbc7fbd45f8eced3c3ff96e83838 519 ProSitePatterns PS00455 Putative AMP-binding domain signature. 173 184 - T 14-10-2018 IPR020845 AMP-binding, conserved site TSH58p_00815 186ff2eb0149bb7fa6773a6de41b851a 428 Pfam PF13599 Pentapeptide repeats (9 copies) 285 344 5.1E-11 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_00815 186ff2eb0149bb7fa6773a6de41b851a 428 Pfam PF13599 Pentapeptide repeats (9 copies) 57 124 8.2E-10 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_00815 186ff2eb0149bb7fa6773a6de41b851a 428 Gene3D G3DSA:2.160.20.80 363 428 1.4E-15 T 14-10-2018 TSH58p_00815 186ff2eb0149bb7fa6773a6de41b851a 428 Gene3D G3DSA:2.160.20.80 255 358 7.4E-21 T 14-10-2018 TSH58p_00815 186ff2eb0149bb7fa6773a6de41b851a 428 SUPERFAMILY SSF141571 138 246 1.7E-27 T 14-10-2018 TSH58p_00815 186ff2eb0149bb7fa6773a6de41b851a 428 Gene3D G3DSA:2.160.20.100 39 135 4.8E-22 T 14-10-2018 TSH58p_00815 186ff2eb0149bb7fa6773a6de41b851a 428 Pfam PF00805 Pentapeptide repeats (8 copies) 155 193 2.7E-13 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_00815 186ff2eb0149bb7fa6773a6de41b851a 428 Pfam PF00805 Pentapeptide repeats (8 copies) 371 409 1.1E-11 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_00815 186ff2eb0149bb7fa6773a6de41b851a 428 Gene3D G3DSA:2.160.20.80 136 249 3.1E-27 T 14-10-2018 TSH58p_00815 186ff2eb0149bb7fa6773a6de41b851a 428 SUPERFAMILY SSF141571 40 124 5.49E-22 T 14-10-2018 TSH58p_00815 186ff2eb0149bb7fa6773a6de41b851a 428 SUPERFAMILY SSF141571 270 422 6.67E-35 T 14-10-2018 TSH58p_20385 3cb1eccf8f3837011efd13f7b83cddad 383 SUPERFAMILY SSF56059 2 380 1.09E-29 T 14-10-2018 TSH58p_20385 3cb1eccf8f3837011efd13f7b83cddad 383 SUPERFAMILY SSF52440 173 275 9.21E-18 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TSH58p_20385 3cb1eccf8f3837011efd13f7b83cddad 383 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 20 381 4.1E-67 T 14-10-2018 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain TSH58p_16875 70d37314553da7d88e838757d4c1d295 351 Gene3D G3DSA:3.40.1090.20 7 74 1.3E-7 T 14-10-2018 TSH58p_16875 70d37314553da7d88e838757d4c1d295 351 SUPERFAMILY SSF52151 5 334 2.43E-52 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TSH58p_16875 70d37314553da7d88e838757d4c1d295 351 Gene3D G3DSA:3.40.1090.10 85 230 1.2E-15 T 14-10-2018 TSH58p_16875 70d37314553da7d88e838757d4c1d295 351 Pfam PF01734 Patatin-like phospholipase 11 168 4.4E-22 T 14-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 TSH58p_25685 b28eaf6f6ab8cc0816c910b6f9adc75e 191 Gene3D G3DSA:3.40.50.150 6 145 1.5E-9 T 14-10-2018 TSH58p_25685 b28eaf6f6ab8cc0816c910b6f9adc75e 191 SUPERFAMILY SSF53335 31 124 4.3E-8 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_15820 d5de0815ab59f673d43a48879a372444 465 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 353 458 9.5E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_15820 d5de0815ab59f673d43a48879a372444 465 SUPERFAMILY SSF158472 190 238 9.29E-8 T 14-10-2018 TSH58p_15820 d5de0815ab59f673d43a48879a372444 465 SUPERFAMILY SSF55874 299 461 1.96E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_15820 d5de0815ab59f673d43a48879a372444 465 SMART SM00304 187 240 1.5E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_15820 d5de0815ab59f673d43a48879a372444 465 SMART SM00387 353 464 2.4E-34 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_15820 d5de0815ab59f673d43a48879a372444 465 SUPERFAMILY SSF47384 224 308 6.08E-13 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_15820 d5de0815ab59f673d43a48879a372444 465 Gene3D G3DSA:1.10.287.130 192 308 1.7E-20 T 14-10-2018 TSH58p_15820 d5de0815ab59f673d43a48879a372444 465 SMART SM00388 241 308 5.2E-7 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_15820 d5de0815ab59f673d43a48879a372444 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 425 443 6.3E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_15820 d5de0815ab59f673d43a48879a372444 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 406 6.3E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_15820 d5de0815ab59f673d43a48879a372444 465 Pfam PF00512 His Kinase A (phospho-acceptor) domain 243 308 8.8E-7 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_15820 d5de0815ab59f673d43a48879a372444 465 Gene3D G3DSA:3.30.565.10 313 463 1.5E-32 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_15820 d5de0815ab59f673d43a48879a372444 465 Pfam PF00672 HAMP domain 189 237 9.4E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_05470 0af8b3d2877f96eaad0fbec550634a49 259 Gene3D G3DSA:3.40.50.1820 7 259 1.9E-67 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_05470 0af8b3d2877f96eaad0fbec550634a49 259 Pfam PF12697 Alpha/beta hydrolase family 21 253 1.4E-23 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_05470 0af8b3d2877f96eaad0fbec550634a49 259 PRINTS PR00412 Epoxide hydrolase signature 236 258 4.4E-9 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TSH58p_05470 0af8b3d2877f96eaad0fbec550634a49 259 PRINTS PR00412 Epoxide hydrolase signature 87 100 4.4E-9 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TSH58p_05470 0af8b3d2877f96eaad0fbec550634a49 259 PRINTS PR00412 Epoxide hydrolase signature 101 114 4.4E-9 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TSH58p_05470 0af8b3d2877f96eaad0fbec550634a49 259 PRINTS PR00412 Epoxide hydrolase signature 44 59 4.4E-9 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TSH58p_05470 0af8b3d2877f96eaad0fbec550634a49 259 SUPERFAMILY SSF53474 3 258 2.39E-55 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_05470 0af8b3d2877f96eaad0fbec550634a49 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 87 100 3.5E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_05470 0af8b3d2877f96eaad0fbec550634a49 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 44 59 3.5E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_05470 0af8b3d2877f96eaad0fbec550634a49 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 101 114 3.5E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_05470 0af8b3d2877f96eaad0fbec550634a49 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 206 220 3.5E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_31470 e05e9c53c471558b42058664ed3a5d4c 351 Gene3D G3DSA:3.20.20.150 19 325 3.8E-72 T 14-10-2018 TSH58p_31470 e05e9c53c471558b42058664ed3a5d4c 351 Pfam PF01261 Xylose isomerase-like TIM barrel 30 279 2.7E-37 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TSH58p_31470 e05e9c53c471558b42058664ed3a5d4c 351 Pfam PF07582 AP endonuclease family 2 C terminus 280 334 2.8E-21 T 14-10-2018 IPR011418 AP endonuclease, family 2, C-terminal TSH58p_31470 e05e9c53c471558b42058664ed3a5d4c 351 SUPERFAMILY SSF51658 8 322 6.55E-62 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily TSH58p_13085 1f927aa0fa53933bd1f04ae7d585d99d 209 Gene3D G3DSA:3.40.50.1240 4 205 7.8E-34 T 14-10-2018 IPR029033 Histidine phosphatase superfamily TSH58p_13085 1f927aa0fa53933bd1f04ae7d585d99d 209 SUPERFAMILY SSF53254 1 202 1.56E-35 T 14-10-2018 IPR029033 Histidine phosphatase superfamily TSH58p_13085 1f927aa0fa53933bd1f04ae7d585d99d 209 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 7 190 2.8E-38 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TSH58p_13085 1f927aa0fa53933bd1f04ae7d585d99d 209 PIRSF PIRSF000709 30 182 3.8E-7 T 14-10-2018 TSH58p_13085 1f927aa0fa53933bd1f04ae7d585d99d 209 SMART SM00855 5 156 3.0E-8 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TSH58p_31265 26a90925e88329400e69605b8cd45527 575 Gene3D G3DSA:3.30.300.30 463 559 8.6E-27 T 14-10-2018 TSH58p_31265 26a90925e88329400e69605b8cd45527 575 Gene3D G3DSA:3.40.50.12780 26 462 2.0E-114 T 14-10-2018 TSH58p_31265 26a90925e88329400e69605b8cd45527 575 Pfam PF13193 AMP-binding enzyme C-terminal domain 477 551 1.4E-18 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSH58p_31265 26a90925e88329400e69605b8cd45527 575 ProSitePatterns PS00455 Putative AMP-binding domain signature. 218 229 - T 14-10-2018 IPR020845 AMP-binding, conserved site TSH58p_31265 26a90925e88329400e69605b8cd45527 575 Pfam PF00501 AMP-binding enzyme 39 466 3.1E-101 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_31265 26a90925e88329400e69605b8cd45527 575 SUPERFAMILY SSF56801 20 558 5.23E-147 T 14-10-2018 TSH58p_12580 338e1e0b00681503ea690d239f6f42b4 368 Gene3D G3DSA:3.40.50.10470 192 357 4.0E-47 T 14-10-2018 TSH58p_12580 338e1e0b00681503ea690d239f6f42b4 368 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 18 349 3.4E-124 T 14-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TSH58p_12580 338e1e0b00681503ea690d239f6f42b4 368 SUPERFAMILY SSF100950 2 352 5.69E-108 T 14-10-2018 IPR037171 NagB/RpiA transferase-like TSH58p_12580 338e1e0b00681503ea690d239f6f42b4 368 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 39 349 6.5E-87 T 14-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TSH58p_12580 338e1e0b00681503ea690d239f6f42b4 368 Pfam PF01008 Initiation factor 2 subunit family 52 350 3.1E-55 T 14-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 TSH58p_12580 338e1e0b00681503ea690d239f6f42b4 368 Gene3D G3DSA:1.20.120.1840 8 191 1.1E-51 T 14-10-2018 TSH58p_12580 338e1e0b00681503ea690d239f6f42b4 368 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 7 360 36.306 T 14-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TSH58p_05950 eeba95a4d1fc512a34d787a3cd9eddc3 444 Hamap MF_00303 Trigger factor [tig]. 1 424 21.795 T 14-10-2018 IPR005215 Trigger factor GO:0015031 TSH58p_05950 eeba95a4d1fc512a34d787a3cd9eddc3 444 Gene3D G3DSA:1.10.3120.10 116 423 5.9E-89 T 14-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 TSH58p_05950 eeba95a4d1fc512a34d787a3cd9eddc3 444 SUPERFAMILY SSF54534 88 243 1.96E-31 T 14-10-2018 TSH58p_05950 eeba95a4d1fc512a34d787a3cd9eddc3 444 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 158 239 2.2E-12 T 14-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain TSH58p_05950 eeba95a4d1fc512a34d787a3cd9eddc3 444 SUPERFAMILY SSF102735 1 129 2.09E-37 T 14-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 TSH58p_05950 eeba95a4d1fc512a34d787a3cd9eddc3 444 PIRSF PIRSF003095 1 440 3.2E-133 T 14-10-2018 IPR005215 Trigger factor GO:0015031 TSH58p_05950 eeba95a4d1fc512a34d787a3cd9eddc3 444 TIGRFAM TIGR00115 tig: trigger factor 11 418 1.1E-128 T 14-10-2018 IPR005215 Trigger factor GO:0015031 TSH58p_05950 eeba95a4d1fc512a34d787a3cd9eddc3 444 Gene3D G3DSA:3.10.50.40 150 248 5.9E-89 T 14-10-2018 TSH58p_05950 eeba95a4d1fc512a34d787a3cd9eddc3 444 Gene3D G3DSA:3.30.70.1050 1 115 6.5E-35 T 14-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 TSH58p_05950 eeba95a4d1fc512a34d787a3cd9eddc3 444 SUPERFAMILY SSF109998 250 435 7.55E-46 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily TSH58p_05950 eeba95a4d1fc512a34d787a3cd9eddc3 444 Pfam PF05697 Bacterial trigger factor protein (TF) 1 144 8.1E-39 T 14-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 TSH58p_05950 eeba95a4d1fc512a34d787a3cd9eddc3 444 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 262 419 3.1E-41 T 14-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 TSH58p_21790 bf1d96d1f78a0c5070128a1ad16b5597 365 Gene3D G3DSA:2.40.100.10 186 322 2.3E-48 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily TSH58p_21790 bf1d96d1f78a0c5070128a1ad16b5597 365 SUPERFAMILY SSF50891 189 303 2.24E-10 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily TSH58p_21790 bf1d96d1f78a0c5070128a1ad16b5597 365 SMART SM00797 31 313 2.1E-106 T 14-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B TSH58p_21790 bf1d96d1f78a0c5070128a1ad16b5597 365 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 10 316 4.2E-81 T 14-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B TSH58p_21790 bf1d96d1f78a0c5070128a1ad16b5597 365 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 32 296 2.5E-78 T 14-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B TSH58p_06805 d78e47cec821568f3c7380c7e9a02c3d 411 Pfam PF04932 O-Antigen ligase 205 345 5.6E-15 T 14-10-2018 IPR007016 O-antigen ligase-related TSH58p_32090 66009d99e0904820bd637ab85ed107d0 355 Pfam PF09361 Phasin protein 249 332 4.4E-7 T 14-10-2018 IPR018968 Phasin TSH58p_32090 66009d99e0904820bd637ab85ed107d0 355 Pfam PF01814 Hemerythrin HHE cation binding domain 17 121 1.8E-13 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 TSH58p_32090 66009d99e0904820bd637ab85ed107d0 355 Gene3D G3DSA:1.20.120.520 8 143 4.3E-11 T 14-10-2018 TSH58p_23745 1b7263f256cf331b5e79e36d26c8b6b8 84 Pfam PF13763 Domain of unknown function (DUF4167) 34 81 1.2E-12 T 14-10-2018 IPR025430 Domain of unknown function DUF4167 TSH58p_00095 6ad744eab4cf737f38898f67c96c3cba 130 SUPERFAMILY SSF54534 54 127 2.35E-8 T 14-10-2018 TSH58p_00095 6ad744eab4cf737f38898f67c96c3cba 130 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 56 125 5.6E-7 T 14-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 TSH58p_00095 6ad744eab4cf737f38898f67c96c3cba 130 PIRSF PIRSF006092 22 129 5.2E-9 T 14-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 TSH58p_00095 6ad744eab4cf737f38898f67c96c3cba 130 Gene3D G3DSA:3.10.50.30 50 130 1.6E-14 T 14-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 TSH58p_04960 87b651cc8f4ecef054747599fbfa4fef 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 1.7E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_04960 87b651cc8f4ecef054747599fbfa4fef 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 1.7E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_04960 87b651cc8f4ecef054747599fbfa4fef 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 1.7E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_04960 87b651cc8f4ecef054747599fbfa4fef 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 1.7E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_04960 87b651cc8f4ecef054747599fbfa4fef 261 Gene3D G3DSA:3.40.50.720 15 207 9.0E-39 T 14-10-2018 TSH58p_04960 87b651cc8f4ecef054747599fbfa4fef 261 PIRSF PIRSF000094 8 261 1.1E-93 T 14-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 TSH58p_04960 87b651cc8f4ecef054747599fbfa4fef 261 Gene3D G3DSA:1.10.8.400 208 261 1.0E-14 T 14-10-2018 TSH58p_04960 87b651cc8f4ecef054747599fbfa4fef 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 258 8.7E-86 T 14-10-2018 TSH58p_04960 87b651cc8f4ecef054747599fbfa4fef 261 SUPERFAMILY SSF51735 12 260 1.79E-66 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_18960 b11af53d88c5c1b26bfe19cddea337d3 493 PRINTS PR00084 Mannitol dehydrogenase signature 29 39 3.9E-20 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 TSH58p_18960 b11af53d88c5c1b26bfe19cddea337d3 493 PRINTS PR00084 Mannitol dehydrogenase signature 179 192 3.9E-20 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 TSH58p_18960 b11af53d88c5c1b26bfe19cddea337d3 493 PRINTS PR00084 Mannitol dehydrogenase signature 218 231 3.9E-20 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 TSH58p_18960 b11af53d88c5c1b26bfe19cddea337d3 493 PRINTS PR00084 Mannitol dehydrogenase signature 248 263 3.9E-20 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 TSH58p_18960 b11af53d88c5c1b26bfe19cddea337d3 493 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 28 188 2.3E-44 T 14-10-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 TSH58p_18960 b11af53d88c5c1b26bfe19cddea337d3 493 SUPERFAMILY SSF48179 283 488 3.26E-69 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_18960 b11af53d88c5c1b26bfe19cddea337d3 493 Gene3D G3DSA:3.40.50.720 1 281 1.8E-109 T 14-10-2018 TSH58p_18960 b11af53d88c5c1b26bfe19cddea337d3 493 SUPERFAMILY SSF51735 2 281 9.84E-101 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_18960 b11af53d88c5c1b26bfe19cddea337d3 493 Gene3D G3DSA:1.10.1040.10 282 491 4.2E-80 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSH58p_18960 b11af53d88c5c1b26bfe19cddea337d3 493 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 216 437 8.5E-86 T 14-10-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 TSH58p_22460 d909d03d9cc155946afc9ad24402214a 267 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 16 242 9.3E-66 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TSH58p_22460 d909d03d9cc155946afc9ad24402214a 267 ProSitePatterns PS01218 TatC family signature. 170 189 - T 14-10-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site TSH58p_22460 d909d03d9cc155946afc9ad24402214a 267 Pfam PF00902 Sec-independent protein translocase protein (TatC) 18 237 9.5E-71 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TSH58p_22460 d909d03d9cc155946afc9ad24402214a 267 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 11 254 17.024 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TSH58p_22460 d909d03d9cc155946afc9ad24402214a 267 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 170 198 1.6E-43 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TSH58p_22460 d909d03d9cc155946afc9ad24402214a 267 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 15 42 1.6E-43 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TSH58p_22460 d909d03d9cc155946afc9ad24402214a 267 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 93 111 1.6E-43 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TSH58p_22460 d909d03d9cc155946afc9ad24402214a 267 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 111 137 1.6E-43 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TSH58p_14630 834a7fb5a8f5bec8af76dd8bf9499e58 264 Gene3D G3DSA:3.40.190.10 44 257 1.7E-21 T 14-10-2018 TSH58p_14630 834a7fb5a8f5bec8af76dd8bf9499e58 264 Gene3D G3DSA:3.40.190.10 121 218 1.7E-21 T 14-10-2018 TSH58p_14630 834a7fb5a8f5bec8af76dd8bf9499e58 264 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 42 260 3.0E-15 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_14630 834a7fb5a8f5bec8af76dd8bf9499e58 264 SUPERFAMILY SSF53850 39 261 7.76E-32 T 14-10-2018 TSH58p_14630 834a7fb5a8f5bec8af76dd8bf9499e58 264 SMART SM00062 38 263 0.0061 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_29150 c5c13f62c755114bba6f99b2b66968ba 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 254 1.7E-40 T 14-10-2018 TSH58p_29150 c5c13f62c755114bba6f99b2b66968ba 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 2.9E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_29150 c5c13f62c755114bba6f99b2b66968ba 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 2.9E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_29150 c5c13f62c755114bba6f99b2b66968ba 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 2.9E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_29150 c5c13f62c755114bba6f99b2b66968ba 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 2.9E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_29150 c5c13f62c755114bba6f99b2b66968ba 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_29150 c5c13f62c755114bba6f99b2b66968ba 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 1.6E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_29150 c5c13f62c755114bba6f99b2b66968ba 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 1.6E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_29150 c5c13f62c755114bba6f99b2b66968ba 256 SUPERFAMILY SSF51735 9 255 8.68E-58 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_29150 c5c13f62c755114bba6f99b2b66968ba 256 Gene3D G3DSA:3.40.50.720 1 255 2.7E-56 T 14-10-2018 TSH58p_24890 e93aa9ca70b3092149cacb452ba507cd 303 Gene3D G3DSA:3.20.20.370 21 273 2.8E-47 T 14-10-2018 TSH58p_24890 e93aa9ca70b3092149cacb452ba507cd 303 Pfam PF01522 Polysaccharide deacetylase 73 237 6.0E-19 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 TSH58p_24890 e93aa9ca70b3092149cacb452ba507cd 303 SUPERFAMILY SSF88713 37 270 2.97E-27 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TSH58p_25690 97d8f34928021fa58ea62e382419fd5c 277 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 11 277 9.9E-99 T 14-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 TSH58p_25690 97d8f34928021fa58ea62e382419fd5c 277 SUPERFAMILY SSF51690 111 277 6.67E-60 T 14-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 TSH58p_25690 97d8f34928021fa58ea62e382419fd5c 277 Gene3D G3DSA:3.20.20.70 114 267 1.0E-104 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_25690 97d8f34928021fa58ea62e382419fd5c 277 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 111 276 5.4E-62 T 14-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 TSH58p_25690 97d8f34928021fa58ea62e382419fd5c 277 SUPERFAMILY SSF54675 4 110 2.71E-29 T 14-10-2018 TSH58p_25690 97d8f34928021fa58ea62e382419fd5c 277 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 22 109 3.7E-24 T 14-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 TSH58p_25690 97d8f34928021fa58ea62e382419fd5c 277 Gene3D G3DSA:3.90.1170.20 13 276 1.0E-104 T 14-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 TSH58p_25690 97d8f34928021fa58ea62e382419fd5c 277 PIRSF PIRSF006250 4 277 5.6E-92 T 14-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 TSH58p_09920 6a30aed871806104d49a311dfcefec83 145 Pfam PF00565 Staphylococcal nuclease homologue 54 131 2.1E-5 T 14-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 TSH58p_09920 6a30aed871806104d49a311dfcefec83 145 SMART SM00318 23 140 8.3E-4 T 14-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 TSH58p_09920 6a30aed871806104d49a311dfcefec83 145 Gene3D G3DSA:2.40.50.90 22 140 5.8E-15 T 14-10-2018 IPR035437 SNase-like, OB-fold superfamily TSH58p_09920 6a30aed871806104d49a311dfcefec83 145 SUPERFAMILY SSF50199 21 137 2.62E-19 T 14-10-2018 TSH58p_27925 b3ef0cda71fd941114e2c51e889c1b21 232 Pfam PF03922 OmpW family 34 232 1.7E-54 T 14-10-2018 IPR005618 Outer membrane protein, OmpW GO:0019867 TSH58p_27925 b3ef0cda71fd941114e2c51e889c1b21 232 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 129 213 6.7E-4 T 14-10-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 TSH58p_27925 b3ef0cda71fd941114e2c51e889c1b21 232 Gene3D G3DSA:2.40.160.20 32 232 1.7E-60 T 14-10-2018 TSH58p_27925 b3ef0cda71fd941114e2c51e889c1b21 232 SUPERFAMILY SSF56925 33 232 6.8E-32 T 14-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel TSH58p_21115 5a6235027c93af78fafffc197e46ef91 268 SUPERFAMILY SSF56317 1 258 3.79E-69 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TSH58p_21115 5a6235027c93af78fafffc197e46ef91 268 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 142 162 - T 14-10-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site TSH58p_21115 5a6235027c93af78fafffc197e46ef91 268 Gene3D G3DSA:3.60.110.10 1 259 2.4E-80 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TSH58p_21115 5a6235027c93af78fafffc197e46ef91 268 Pfam PF00795 Carbon-nitrogen hydrolase 5 241 1.0E-45 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 TSH58p_08325 12835f0c42d9b735d3dccc4f8a662ddf 222 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 15 110 4.1E-27 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 TSH58p_08325 12835f0c42d9b735d3dccc4f8a662ddf 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 39 202 5.5E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_08325 12835f0c42d9b735d3dccc4f8a662ddf 222 Gene3D G3DSA:1.10.3720.10 2 215 3.3E-56 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_08325 12835f0c42d9b735d3dccc4f8a662ddf 222 SUPERFAMILY SSF161098 14 203 3.49E-44 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_23900 fee1a871127df6f76fde9051840c1241 183 Pfam PF06041 Bacterial protein of unknown function (DUF924) 9 180 4.8E-58 T 14-10-2018 IPR010323 Protein of unknown function DUF924 TSH58p_23900 fee1a871127df6f76fde9051840c1241 183 Gene3D G3DSA:1.20.58.320 2 81 8.9E-25 T 14-10-2018 TSH58p_23900 fee1a871127df6f76fde9051840c1241 183 SUPERFAMILY SSF48452 5 179 1.48E-63 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_23900 fee1a871127df6f76fde9051840c1241 183 Gene3D G3DSA:1.25.40.10 82 183 7.6E-35 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_20850 bd6cdc7e1f2bb276623a52be297cecf8 131 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 123 8.3E-11 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TSH58p_20850 bd6cdc7e1f2bb276623a52be297cecf8 131 Gene3D G3DSA:3.10.180.10 2 128 7.3E-29 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSH58p_20850 bd6cdc7e1f2bb276623a52be297cecf8 131 SUPERFAMILY SSF54593 5 127 2.28E-27 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSH58p_12115 337051647b78c8dc784719b29355a705 268 Gene3D G3DSA:3.40.50.300 12 266 5.0E-75 T 14-10-2018 TSH58p_12115 337051647b78c8dc784719b29355a705 268 Pfam PF00005 ABC transporter 30 189 9.6E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_12115 337051647b78c8dc784719b29355a705 268 SMART SM00382 39 237 5.0E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_12115 337051647b78c8dc784719b29355a705 268 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_12115 337051647b78c8dc784719b29355a705 268 SUPERFAMILY SSF52540 16 259 7.99E-74 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_12115 337051647b78c8dc784719b29355a705 268 PIRSF PIRSF039085 11 265 4.8E-118 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 TSH58p_13035 d529b51401421dc0c7022e03d6ce2901 230 SMART SM00419 169 217 5.5E-5 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_13035 d529b51401421dc0c7022e03d6ce2901 230 Pfam PF00027 Cyclic nucleotide-binding domain 39 126 1.0E-10 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_13035 d529b51401421dc0c7022e03d6ce2901 230 SUPERFAMILY SSF51206 16 154 8.38E-26 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like TSH58p_13035 d529b51401421dc0c7022e03d6ce2901 230 SUPERFAMILY SSF46785 158 224 1.63E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_13035 d529b51401421dc0c7022e03d6ce2901 230 Gene3D G3DSA:1.10.10.10 153 226 8.9E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_13035 d529b51401421dc0c7022e03d6ce2901 230 Pfam PF13545 Crp-like helix-turn-helix domain 160 223 1.1E-14 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_13035 d529b51401421dc0c7022e03d6ce2901 230 Gene3D G3DSA:2.60.120.10 12 152 1.1E-39 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_04585 2d1b7bab5b33c24394a9afc0151846cb 366 SUPERFAMILY SSF53850 27 365 8.28E-80 T 14-10-2018 TSH58p_04585 2d1b7bab5b33c24394a9afc0151846cb 366 Gene3D G3DSA:3.40.190.10 134 360 1.9E-111 T 14-10-2018 TSH58p_04585 2d1b7bab5b33c24394a9afc0151846cb 366 PIRSF PIRSF019574 1 366 6.1E-108 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSH58p_04585 2d1b7bab5b33c24394a9afc0151846cb 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 125 141 6.8E-37 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSH58p_04585 2d1b7bab5b33c24394a9afc0151846cb 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 310 336 6.8E-37 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSH58p_04585 2d1b7bab5b33c24394a9afc0151846cb 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 92 105 6.8E-37 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSH58p_04585 2d1b7bab5b33c24394a9afc0151846cb 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 32 48 6.8E-37 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSH58p_04585 2d1b7bab5b33c24394a9afc0151846cb 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 48 69 6.8E-37 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSH58p_04585 2d1b7bab5b33c24394a9afc0151846cb 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 265 284 6.8E-37 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSH58p_04585 2d1b7bab5b33c24394a9afc0151846cb 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 155 169 6.8E-37 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSH58p_04585 2d1b7bab5b33c24394a9afc0151846cb 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 178 197 6.8E-37 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSH58p_04585 2d1b7bab5b33c24394a9afc0151846cb 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 215 234 6.8E-37 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSH58p_04585 2d1b7bab5b33c24394a9afc0151846cb 366 Gene3D G3DSA:3.40.190.10 29 334 1.9E-111 T 14-10-2018 TSH58p_04585 2d1b7bab5b33c24394a9afc0151846cb 366 Pfam PF13416 Bacterial extracellular solute-binding protein 44 331 1.2E-23 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSH58p_03380 66c318e11c5e57bc3565a8d8fd86de35 308 SUPERFAMILY SSF63829 23 305 4.14E-60 T 14-10-2018 TSH58p_03380 66c318e11c5e57bc3565a8d8fd86de35 308 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 150 172 1.0E-23 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TSH58p_03380 66c318e11c5e57bc3565a8d8fd86de35 308 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 26 43 1.0E-23 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TSH58p_03380 66c318e11c5e57bc3565a8d8fd86de35 308 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 106 127 1.0E-23 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TSH58p_03380 66c318e11c5e57bc3565a8d8fd86de35 308 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 215 232 1.0E-23 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TSH58p_03380 66c318e11c5e57bc3565a8d8fd86de35 308 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 257 275 1.0E-23 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TSH58p_03380 66c318e11c5e57bc3565a8d8fd86de35 308 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 26 274 3.5E-68 T 14-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region TSH58p_03380 66c318e11c5e57bc3565a8d8fd86de35 308 Gene3D G3DSA:2.120.10.30 14 306 1.4E-84 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TSH58p_24155 2e0432c170cfe50d893de55e28d0a6b5 688 SUPERFAMILY SSF64518 214 687 4.18E-11 T 14-10-2018 TSH58p_24155 2e0432c170cfe50d893de55e28d0a6b5 688 SUPERFAMILY SSF64518 7 204 5.1E-11 T 14-10-2018 TSH58p_05905 813cb3a12572de646ea8b31901f3eec9 209 Gene3D G3DSA:3.30.460.80 1 133 1.1E-44 T 14-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05905 813cb3a12572de646ea8b31901f3eec9 209 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 33 152 1.1E-45 T 14-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05905 813cb3a12572de646ea8b31901f3eec9 209 SUPERFAMILY SSF143243 8 187 4.58E-62 T 14-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05905 813cb3a12572de646ea8b31901f3eec9 209 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 34 154 1.9E-46 T 14-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05905 813cb3a12572de646ea8b31901f3eec9 209 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 9 161 30.778 T 14-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05905 813cb3a12572de646ea8b31901f3eec9 209 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 114 135 - T 14-10-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05905 813cb3a12572de646ea8b31901f3eec9 209 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 85 140 5.0E-14 T 14-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_10715 adb44a7154f7cd639162a5c5c2d0fcc3 199 Pfam PF01569 PAP2 superfamily 82 190 1.3E-12 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase TSH58p_10715 adb44a7154f7cd639162a5c5c2d0fcc3 199 Gene3D G3DSA:1.20.144.10 106 197 3.0E-10 T 14-10-2018 TSH58p_10715 adb44a7154f7cd639162a5c5c2d0fcc3 199 SMART SM00014 77 188 7.5E-7 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase TSH58p_10715 adb44a7154f7cd639162a5c5c2d0fcc3 199 SUPERFAMILY SSF48317 54 194 5.49E-20 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily TSH58p_07480 981fa31ca96f2541eb40b9d66bf4a14d 448 PIRSF PIRSF000139 5 427 4.0E-126 T 14-10-2018 TSH58p_07480 981fa31ca96f2541eb40b9d66bf4a14d 448 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 76 87 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_07480 981fa31ca96f2541eb40b9d66bf4a14d 448 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 25 36 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_07480 981fa31ca96f2541eb40b9d66bf4a14d 448 SUPERFAMILY SSF54862 22 118 1.51E-20 T 14-10-2018 TSH58p_07480 981fa31ca96f2541eb40b9d66bf4a14d 448 Pfam PF02754 Cysteine-rich domain 185 270 1.5E-12 T 14-10-2018 IPR004017 Cysteine-rich domain TSH58p_07480 981fa31ca96f2541eb40b9d66bf4a14d 448 Pfam PF02754 Cysteine-rich domain 317 400 3.4E-11 T 14-10-2018 IPR004017 Cysteine-rich domain TSH58p_07480 981fa31ca96f2541eb40b9d66bf4a14d 448 Pfam PF12838 4Fe-4S dicluster domain 24 90 9.4E-12 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_07480 981fa31ca96f2541eb40b9d66bf4a14d 448 Gene3D G3DSA:1.10.1060.10 5 111 2.1E-8 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSH58p_28600 17dbb6dd2c14c63bb86311f8cfb07e99 246 SMART SM00895 91 217 1.1E-13 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_28600 17dbb6dd2c14c63bb86311f8cfb07e99 246 Gene3D G3DSA:1.20.120.530 84 225 1.0E-25 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_28600 17dbb6dd2c14c63bb86311f8cfb07e99 246 SMART SM00345 23 81 7.2E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_28600 17dbb6dd2c14c63bb86311f8cfb07e99 246 Pfam PF07729 FCD domain 91 216 3.9E-17 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_28600 17dbb6dd2c14c63bb86311f8cfb07e99 246 Gene3D G3DSA:1.10.10.10 6 83 2.0E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_28600 17dbb6dd2c14c63bb86311f8cfb07e99 246 SUPERFAMILY SSF48008 88 222 6.54E-24 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_28600 17dbb6dd2c14c63bb86311f8cfb07e99 246 SUPERFAMILY SSF46785 21 85 4.99E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_28600 17dbb6dd2c14c63bb86311f8cfb07e99 246 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 81 4.0E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_22115 253f3d5e60f16fa2a4909c3b10a09739 232 Pfam PF07568 Histidine kinase 38 110 7.3E-17 T 14-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain TSH58p_22115 253f3d5e60f16fa2a4909c3b10a09739 232 SUPERFAMILY SSF55874 94 226 1.15E-19 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_22115 253f3d5e60f16fa2a4909c3b10a09739 232 Pfam PF13581 Histidine kinase-like ATPase domain 122 196 1.7E-9 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_22115 253f3d5e60f16fa2a4909c3b10a09739 232 Gene3D G3DSA:3.30.450.20 5 89 6.6E-6 T 14-10-2018 TSH58p_22115 253f3d5e60f16fa2a4909c3b10a09739 232 SMART SM00387 131 230 5.2E-12 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_22115 253f3d5e60f16fa2a4909c3b10a09739 232 Gene3D G3DSA:3.30.565.10 95 231 2.1E-29 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_08145 9a6d63aa0ad8531c250b5864c0de13bb 136 Pfam PF01724 Domain of unknown function DUF29 5 127 2.3E-28 T 14-10-2018 IPR002636 Protein from unkown function DUF29 TSH58p_08145 9a6d63aa0ad8531c250b5864c0de13bb 136 Gene3D G3DSA:1.20.1220.20 1 133 7.7E-30 T 14-10-2018 TSH58p_18425 bc051ac96525288559703344012a7616 322 Gene3D G3DSA:3.40.50.720 5 302 7.1E-117 T 14-10-2018 TSH58p_18425 bc051ac96525288559703344012a7616 322 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 3 322 47.6 T 14-10-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 TSH58p_18425 bc051ac96525288559703344012a7616 322 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 311 2.7E-102 T 14-10-2018 IPR016040 NAD(P)-binding domain TSH58p_18425 bc051ac96525288559703344012a7616 322 Gene3D G3DSA:3.90.25.10 186 314 7.1E-117 T 14-10-2018 TSH58p_18425 bc051ac96525288559703344012a7616 322 SUPERFAMILY SSF51735 3 315 1.1E-65 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_31405 af5d5ccf42553769e1c21701dae1aa45 191 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 163 6.7E-26 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TSH58p_31405 af5d5ccf42553769e1c21701dae1aa45 191 SUPERFAMILY SSF88659 96 165 2.4E-14 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSH58p_31405 af5d5ccf42553769e1c21701dae1aa45 191 SUPERFAMILY SSF88946 8 87 1.02E-14 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_31405 af5d5ccf42553769e1c21701dae1aa45 191 Pfam PF08281 Sigma-70, region 4 116 165 5.0E-16 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_31405 af5d5ccf42553769e1c21701dae1aa45 191 Gene3D G3DSA:1.10.10.10 107 172 1.3E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_31405 af5d5ccf42553769e1c21701dae1aa45 191 Gene3D G3DSA:1.10.1740.10 2 79 2.2E-9 T 14-10-2018 TSH58p_31405 af5d5ccf42553769e1c21701dae1aa45 191 Pfam PF04542 Sigma-70 region 2 12 78 3.2E-13 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_22620 90e803a2f890f82fbb72df33f2b21620 154 Pfam PF00959 Phage lysozyme 36 145 1.1E-18 T 14-10-2018 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 TSH58p_22620 90e803a2f890f82fbb72df33f2b21620 154 SUPERFAMILY SSF53955 8 153 7.67E-47 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily TSH58p_22620 90e803a2f890f82fbb72df33f2b21620 154 Gene3D G3DSA:1.10.530.40 1 154 9.7E-51 T 14-10-2018 TSH58p_17200 0f6973b361e6fe9c379d54a27d0159e1 149 Gene3D G3DSA:3.40.630.30 1 147 1.7E-36 T 14-10-2018 TSH58p_17200 0f6973b361e6fe9c379d54a27d0159e1 149 SUPERFAMILY SSF55729 1 148 7.27E-27 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_17200 0f6973b361e6fe9c379d54a27d0159e1 149 Pfam PF13673 Acetyltransferase (GNAT) domain 47 148 1.4E-14 T 14-10-2018 IPR000182 GNAT domain TSH58p_16080 5901e3e666da1b3ff2aa142b486c7d95 418 Pfam PF00675 Insulinase (Peptidase family M16) 13 159 7.5E-42 T 14-10-2018 IPR011765 Peptidase M16, N-terminal TSH58p_16080 5901e3e666da1b3ff2aa142b486c7d95 418 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 34 57 - T 14-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 TSH58p_16080 5901e3e666da1b3ff2aa142b486c7d95 418 SUPERFAMILY SSF63411 222 413 2.39E-50 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TSH58p_16080 5901e3e666da1b3ff2aa142b486c7d95 418 Pfam PF05193 Peptidase M16 inactive domain 167 338 2.3E-38 T 14-10-2018 IPR007863 Peptidase M16, C-terminal TSH58p_16080 5901e3e666da1b3ff2aa142b486c7d95 418 SUPERFAMILY SSF63411 2 206 6.97E-57 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TSH58p_16080 5901e3e666da1b3ff2aa142b486c7d95 418 Gene3D G3DSA:3.30.830.10 3 216 2.3E-67 T 14-10-2018 TSH58p_16080 5901e3e666da1b3ff2aa142b486c7d95 418 Gene3D G3DSA:3.30.830.10 217 417 1.2E-65 T 14-10-2018 TSH58p_20785 c15e2bebd1d91bade9c0ec7ffbdba911 446 SUPERFAMILY SSF75304 3 445 2.62E-123 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_20785 c15e2bebd1d91bade9c0ec7ffbdba911 446 Gene3D G3DSA:3.90.1300.10 5 445 2.7E-132 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_20785 c15e2bebd1d91bade9c0ec7ffbdba911 446 Pfam PF01425 Amidase 38 434 1.0E-92 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_20785 c15e2bebd1d91bade9c0ec7ffbdba911 446 ProSitePatterns PS00571 Amidases signature. 152 183 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 TSH58p_03225 d517eb45828f175c0b30c9623cfdc295 197 Gene3D G3DSA:3.40.50.150 6 196 8.0E-42 T 14-10-2018 TSH58p_03225 d517eb45828f175c0b30c9623cfdc295 197 SUPERFAMILY SSF53335 22 195 3.38E-32 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_03225 d517eb45828f175c0b30c9623cfdc295 197 Pfam PF13578 Methyltransferase domain 56 159 2.1E-19 T 14-10-2018 TSH58p_15405 94c93065adb4ed68f933a677bf126a5f 261 TIGRFAM TIGR02488 flgG_G_neg: flagellar basal-body rod protein FlgG 3 260 5.1E-109 T 14-10-2018 IPR012834 Flagellar basal-body rod FlgG GO:0009426|GO:0071973 TSH58p_15405 94c93065adb4ed68f933a677bf126a5f 261 Pfam PF00460 Flagella basal body rod protein 6 34 3.8E-10 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 TSH58p_15405 94c93065adb4ed68f933a677bf126a5f 261 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 182 260 1.2E-26 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain TSH58p_15405 94c93065adb4ed68f933a677bf126a5f 261 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 146 243 3.9E-31 T 14-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G TSH58p_15405 94c93065adb4ed68f933a677bf126a5f 261 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 136 5.9E-48 T 14-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G TSH58p_15405 94c93065adb4ed68f933a677bf126a5f 261 SUPERFAMILY SSF117143 93 222 3.14E-37 T 14-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like TSH58p_17875 6cfc0848246c6b04963f83d7a60d9eea 365 SUPERFAMILY SSF53335 192 300 6.93E-6 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_13335 4f6c57b223ddd21232d546d738e5d587 321 SUPERFAMILY SSF161098 93 298 8.24E-19 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_13335 4f6c57b223ddd21232d546d738e5d587 321 Gene3D G3DSA:1.10.3720.10 86 308 9.6E-26 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_13335 4f6c57b223ddd21232d546d738e5d587 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 315 6.4E-44 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_04190 cbab9f8018ec685c366dd82169e70810 399 Pfam PF05762 VWA domain containing CoxE-like protein 154 373 1.5E-76 T 14-10-2018 IPR008912 Uncharacterised protein family CoxE-like TSH58p_04190 cbab9f8018ec685c366dd82169e70810 399 PIRSF PIRSF010256 1 383 2.9E-129 T 14-10-2018 IPR011195 Uncharacterised conserved protein UCP010256 TSH58p_04190 cbab9f8018ec685c366dd82169e70810 399 Gene3D G3DSA:3.40.50.410 211 335 9.9E-9 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TSH58p_04190 cbab9f8018ec685c366dd82169e70810 399 SMART SM00327 209 366 3.3E-4 T 14-10-2018 IPR002035 von Willebrand factor, type A TSH58p_04190 cbab9f8018ec685c366dd82169e70810 399 SUPERFAMILY SSF53300 209 340 1.38E-19 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TSH58p_28705 f261922171c441119e464e9451ed8d4b 224 Gene3D G3DSA:1.10.3720.10 3 216 3.4E-54 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_28705 f261922171c441119e464e9451ed8d4b 224 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 15 111 3.9E-33 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 TSH58p_28705 f261922171c441119e464e9451ed8d4b 224 SUPERFAMILY SSF161098 14 202 4.58E-45 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_28705 f261922171c441119e464e9451ed8d4b 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 209 5.9E-19 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_01310 06ce8445f8e6d92708bd83ce98f25cc0 336 SUPERFAMILY SSF46689 197 245 2.6E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_01310 06ce8445f8e6d92708bd83ce98f25cc0 336 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 248 290 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 TSH58p_01310 06ce8445f8e6d92708bd83ce98f25cc0 336 SMART SM00342 211 294 4.7E-30 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TSH58p_01310 06ce8445f8e6d92708bd83ce98f25cc0 336 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 278 294 5.7E-6 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TSH58p_01310 06ce8445f8e6d92708bd83ce98f25cc0 336 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 263 278 5.7E-6 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TSH58p_01310 06ce8445f8e6d92708bd83ce98f25cc0 336 Gene3D G3DSA:1.10.10.60 193 300 7.4E-31 T 14-10-2018 TSH58p_01310 06ce8445f8e6d92708bd83ce98f25cc0 336 SUPERFAMILY SSF46689 248 298 1.52E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_01310 06ce8445f8e6d92708bd83ce98f25cc0 336 Pfam PF12833 Helix-turn-helix domain 217 295 4.6E-22 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TSH58p_13550 3ae1573e234c417cafe0acad6978a356 398 PIRSF PIRSF000724 1 398 1.3E-145 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_13550 3ae1573e234c417cafe0acad6978a356 398 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 16 26 - T 14-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_13550 3ae1573e234c417cafe0acad6978a356 398 SUPERFAMILY SSF53748 4 397 6.24E-147 T 14-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_13550 3ae1573e234c417cafe0acad6978a356 398 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 6 397 39.011 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_13550 3ae1573e234c417cafe0acad6978a356 398 Gene3D G3DSA:3.40.50.1260 170 387 5.6E-148 T 14-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_13550 3ae1573e234c417cafe0acad6978a356 398 Pfam PF00162 Phosphoglycerate kinase 7 387 4.1E-147 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_13550 3ae1573e234c417cafe0acad6978a356 398 PRINTS PR00477 Phosphoglycerate kinase family signature 168 190 9.2E-78 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_13550 3ae1573e234c417cafe0acad6978a356 398 PRINTS PR00477 Phosphoglycerate kinase family signature 313 338 9.2E-78 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_13550 3ae1573e234c417cafe0acad6978a356 398 PRINTS PR00477 Phosphoglycerate kinase family signature 32 54 9.2E-78 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_13550 3ae1573e234c417cafe0acad6978a356 398 PRINTS PR00477 Phosphoglycerate kinase family signature 110 125 9.2E-78 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_13550 3ae1573e234c417cafe0acad6978a356 398 PRINTS PR00477 Phosphoglycerate kinase family signature 191 210 9.2E-78 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_13550 3ae1573e234c417cafe0acad6978a356 398 PRINTS PR00477 Phosphoglycerate kinase family signature 11 27 9.2E-78 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_13550 3ae1573e234c417cafe0acad6978a356 398 PRINTS PR00477 Phosphoglycerate kinase family signature 350 361 9.2E-78 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_13550 3ae1573e234c417cafe0acad6978a356 398 PRINTS PR00477 Phosphoglycerate kinase family signature 373 390 9.2E-78 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_13550 3ae1573e234c417cafe0acad6978a356 398 PRINTS PR00477 Phosphoglycerate kinase family signature 138 160 9.2E-78 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_13550 3ae1573e234c417cafe0acad6978a356 398 Gene3D G3DSA:3.40.50.1260 8 395 5.6E-148 T 14-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSH58p_12155 501301d89e62bc3f8e14ef0e8b1200bc 124 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 16 92 2.2E-25 T 14-10-2018 IPR003746 Protein of unknown function DUF167 TSH58p_12155 501301d89e62bc3f8e14ef0e8b1200bc 124 SUPERFAMILY SSF69786 11 99 1.7E-24 T 14-10-2018 IPR036591 YggU-like superfamily TSH58p_12155 501301d89e62bc3f8e14ef0e8b1200bc 124 Gene3D G3DSA:3.30.1200.10 7 113 1.6E-27 T 14-10-2018 IPR036591 YggU-like superfamily TSH58p_12155 501301d89e62bc3f8e14ef0e8b1200bc 124 SMART SM01152 13 94 2.1E-33 T 14-10-2018 IPR003746 Protein of unknown function DUF167 TSH58p_12155 501301d89e62bc3f8e14ef0e8b1200bc 124 Hamap MF_00634 UPF0235 protein YggU [yggU]. 13 105 19.314 T 14-10-2018 IPR003746 Protein of unknown function DUF167 TSH58p_12185 252b716f2eea96c7d01b9bf88cbee427 202 SUPERFAMILY SSF52141 5 194 1.67E-57 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSH58p_12185 252b716f2eea96c7d01b9bf88cbee427 202 Pfam PF03167 Uracil DNA glycosylase superfamily 32 186 2.8E-23 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSH58p_12185 252b716f2eea96c7d01b9bf88cbee427 202 SMART SM00987 29 187 6.3E-29 T 14-10-2018 TSH58p_12185 252b716f2eea96c7d01b9bf88cbee427 202 SMART SM00986 29 187 6.3E-29 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSH58p_12185 252b716f2eea96c7d01b9bf88cbee427 202 Gene3D G3DSA:3.40.470.10 1 197 1.9E-68 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSH58p_10190 05e7331d3131bb6362137f14651501c0 265 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 4 245 3.5E-76 T 14-10-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 TSH58p_10190 05e7331d3131bb6362137f14651501c0 265 SUPERFAMILY SSF56112 17 245 6.56E-30 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily TSH58p_16555 b1e9b3469e1c81e0f2bec7f3e5c7e4b3 279 SUPERFAMILY SSF53335 17 253 2.74E-38 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_16555 b1e9b3469e1c81e0f2bec7f3e5c7e4b3 279 Gene3D G3DSA:3.40.50.150 12 263 9.3E-39 T 14-10-2018 TSH58p_16555 b1e9b3469e1c81e0f2bec7f3e5c7e4b3 279 Pfam PF13649 Methyltransferase domain 55 152 6.4E-18 T 14-10-2018 TSH58p_32455 6a20848e87a8ed4a956ee2750aa47764 312 Pfam PF05853 beta-keto acid cleavage enzyme 7 304 8.1E-103 T 14-10-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247 TSH58p_32455 6a20848e87a8ed4a956ee2750aa47764 312 Gene3D G3DSA:3.20.20.70 2 312 1.4E-121 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_21155 bb793713bca44528a74ece931b41f296 335 Gene3D G3DSA:3.40.50.300 6 334 3.3E-97 T 14-10-2018 TSH58p_21155 bb793713bca44528a74ece931b41f296 335 SUPERFAMILY SSF52540 51 321 2.66E-69 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_21155 bb793713bca44528a74ece931b41f296 335 Pfam PF00005 ABC transporter 43 193 5.0E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_21155 bb793713bca44528a74ece931b41f296 335 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_21155 bb793713bca44528a74ece931b41f296 335 SMART SM00382 51 243 3.7E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_21155 bb793713bca44528a74ece931b41f296 335 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 243 329 9.8E-27 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_21155 bb793713bca44528a74ece931b41f296 335 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 245 309 6.8E-18 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_21390 d4aa5159320ac2cf6a55c31604f00c74 325 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 9 123 1.9E-19 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 TSH58p_21390 d4aa5159320ac2cf6a55c31604f00c74 325 SUPERFAMILY SSF51735 5 174 9.17E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_21390 d4aa5159320ac2cf6a55c31604f00c74 325 Gene3D G3DSA:3.30.360.10 126 325 3.1E-73 T 14-10-2018 TSH58p_21390 d4aa5159320ac2cf6a55c31604f00c74 325 Gene3D G3DSA:3.40.50.720 2 125 2.0E-31 T 14-10-2018 TSH58p_24620 333f9f950898394cc8ab383e4b9de792 251 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 66 235 3.7E-16 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_24620 333f9f950898394cc8ab383e4b9de792 251 Gene3D G3DSA:1.10.3720.10 1 248 4.5E-53 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_24620 333f9f950898394cc8ab383e4b9de792 251 SUPERFAMILY SSF161098 2 245 6.41E-58 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_12740 ed12667b09b46971713aec49685c5613 220 SUPERFAMILY SSF52540 1 212 2.74E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_12740 ed12667b09b46971713aec49685c5613 220 Pfam PF02224 Cytidylate kinase 5 203 1.4E-52 T 14-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 TSH58p_12740 ed12667b09b46971713aec49685c5613 220 TIGRFAM TIGR00017 cmk: cytidylate kinase 3 201 4.3E-48 T 14-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 TSH58p_12740 ed12667b09b46971713aec49685c5613 220 Hamap MF_00238 Cytidylate kinase [cmk]. 3 214 29.919 T 14-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 TSH58p_12740 ed12667b09b46971713aec49685c5613 220 Gene3D G3DSA:3.40.50.300 2 215 6.3E-63 T 14-10-2018 TSH58p_15285 01338b35041878da1762f7998c6bfe15 290 SUPERFAMILY SSF53187 31 277 9.42E-77 T 14-10-2018 TSH58p_15285 01338b35041878da1762f7998c6bfe15 290 PIRSF PIRSF029730 27 285 4.1E-94 T 14-10-2018 IPR011227 Uncharacterised conserved protein UCP029730 TSH58p_15285 01338b35041878da1762f7998c6bfe15 290 Gene3D G3DSA:3.40.630.40 38 280 5.1E-83 T 14-10-2018 TSH58p_15285 01338b35041878da1762f7998c6bfe15 290 Pfam PF05013 N-formylglutamate amidohydrolase 48 255 3.4E-47 T 14-10-2018 IPR007709 N-formylglutamate amidohydrolase TSH58p_29090 be88bece0a877acfc89931af07f9abbe 562 Gene3D G3DSA:3.40.50.1820 24 354 2.0E-82 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_29090 be88bece0a877acfc89931af07f9abbe 562 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 335 556 5.8E-24 T 14-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 TSH58p_29090 be88bece0a877acfc89931af07f9abbe 562 Gene3D G3DSA:2.60.120.260 364 562 1.5E-43 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily TSH58p_29090 be88bece0a877acfc89931af07f9abbe 562 SUPERFAMILY SSF49785 351 561 4.68E-47 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily TSH58p_29090 be88bece0a877acfc89931af07f9abbe 562 SMART SM00939 323 557 1.6E-51 T 14-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 TSH58p_29090 be88bece0a877acfc89931af07f9abbe 562 SUPERFAMILY SSF53474 11 357 3.43E-40 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_29090 be88bece0a877acfc89931af07f9abbe 562 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 25 560 2.5E-107 T 14-10-2018 IPR005674 CocE/Serine esterase GO:0016787 TSH58p_29090 be88bece0a877acfc89931af07f9abbe 562 Gene3D G3DSA:1.10.3020.10 155 242 2.0E-82 T 14-10-2018 TSH58p_29090 be88bece0a877acfc89931af07f9abbe 562 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 29 292 1.6E-53 T 14-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 TSH58p_23325 2d0c79da60d3ece0863d19be20a2eecb 199 Gene3D G3DSA:1.10.530.10 40 172 4.8E-9 T 14-10-2018 TSH58p_23325 2d0c79da60d3ece0863d19be20a2eecb 199 Pfam PF01464 Transglycosylase SLT domain 48 163 1.7E-5 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 TSH58p_23325 2d0c79da60d3ece0863d19be20a2eecb 199 SUPERFAMILY SSF53955 43 162 1.34E-17 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily TSH58p_29610 00e8d6c1e7f3768bb0dbe2ad3a19601c 327 Gene3D G3DSA:2.40.128.130 36 327 4.6E-54 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily TSH58p_29610 00e8d6c1e7f3768bb0dbe2ad3a19601c 327 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 62 327 4.7E-14 T 14-10-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 TSH58p_29610 00e8d6c1e7f3768bb0dbe2ad3a19601c 327 SUPERFAMILY SSF103515 15 327 4.58E-42 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily TSH58p_29610 00e8d6c1e7f3768bb0dbe2ad3a19601c 327 Pfam PF03797 Autotransporter beta-domain 60 305 1.0E-44 T 14-10-2018 IPR005546 Autotransporter beta-domain TSH58p_29610 00e8d6c1e7f3768bb0dbe2ad3a19601c 327 SMART SM00869 53 316 2.7E-28 T 14-10-2018 IPR005546 Autotransporter beta-domain TSH58p_21815 14647756b1d360b63115f9c290980372 337 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 10 123 8.5E-31 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TSH58p_21815 14647756b1d360b63115f9c290980372 337 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 10 335 5.7E-114 T 14-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TSH58p_21815 14647756b1d360b63115f9c290980372 337 SUPERFAMILY SSF55347 132 324 1.22E-70 T 14-10-2018 TSH58p_21815 14647756b1d360b63115f9c290980372 337 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 8 337 33.684 T 14-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TSH58p_21815 14647756b1d360b63115f9c290980372 337 SUPERFAMILY SSF51735 10 159 8.2E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_21815 14647756b1d360b63115f9c290980372 337 Gene3D G3DSA:3.30.360.10 131 320 2.2E-128 T 14-10-2018 TSH58p_21815 14647756b1d360b63115f9c290980372 337 Gene3D G3DSA:3.40.50.720 11 334 2.2E-128 T 14-10-2018 TSH58p_21815 14647756b1d360b63115f9c290980372 337 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 142 323 3.4E-50 T 14-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TSH58p_21815 14647756b1d360b63115f9c290980372 337 PIRSF PIRSF000148 8 337 6.7E-117 T 14-10-2018 TSH58p_21815 14647756b1d360b63115f9c290980372 337 SMART SM00859 10 125 1.9E-33 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TSH58p_14650 8a7b33f1c8dca722365dae9bce169491 217 Gene3D G3DSA:3.90.730.10 31 215 3.8E-34 T 14-10-2018 IPR036430 Ribonuclease T2-like superfamily GO:0003723|GO:0033897 Reactome: R-HSA-6798695 TSH58p_14650 8a7b33f1c8dca722365dae9bce169491 217 ProSitePatterns PS00530 Ribonuclease T2 family histidine active site 1. 67 74 - T 14-10-2018 IPR018188 Ribonuclease T2, His active site 1 GO:0003723|GO:0033897 Reactome: R-HSA-6798695 TSH58p_14650 8a7b33f1c8dca722365dae9bce169491 217 ProSitePatterns PS00531 Ribonuclease T2 family histidine active site 2. 108 119 - T 14-10-2018 IPR033130 Ribonuclease T2, His active site 2 Reactome: R-HSA-6798695 TSH58p_14650 8a7b33f1c8dca722365dae9bce169491 217 Pfam PF00445 Ribonuclease T2 family 35 199 7.5E-16 T 14-10-2018 IPR001568 Ribonuclease T2-like GO:0003723|GO:0033897 Reactome: R-HSA-6798695 TSH58p_14650 8a7b33f1c8dca722365dae9bce169491 217 SUPERFAMILY SSF55895 31 209 6.15E-40 T 14-10-2018 IPR036430 Ribonuclease T2-like superfamily GO:0003723|GO:0033897 Reactome: R-HSA-6798695 TSH58p_24920 583d72918e7890b62fc0b743bd1333e8 368 SUPERFAMILY SSF55729 22 273 3.45E-13 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_24920 583d72918e7890b62fc0b743bd1333e8 368 Gene3D G3DSA:3.40.630.30 11 140 1.4E-7 T 14-10-2018 TSH58p_24920 583d72918e7890b62fc0b743bd1333e8 368 Pfam PF13527 Acetyltransferase (GNAT) domain 58 138 1.1E-6 T 14-10-2018 TSH58p_30375 a79bbf2515a248ba6bc24e9ebe7296b8 270 Gene3D G3DSA:3.40.50.300 22 189 2.1E-31 T 14-10-2018 TSH58p_30375 a79bbf2515a248ba6bc24e9ebe7296b8 270 Pfam PF08406 CbbQ/NirQ/NorQ C-terminal 184 266 5.3E-31 T 14-10-2018 IPR013615 CbbQ/NirQ/NorQ, C-terminal TSH58p_30375 a79bbf2515a248ba6bc24e9ebe7296b8 270 Pfam PF07728 AAA domain (dynein-related subfamily) 37 171 4.8E-38 T 14-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 TSH58p_30375 a79bbf2515a248ba6bc24e9ebe7296b8 270 SUPERFAMILY SSF52540 29 233 1.08E-34 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_20285 0ff101873b4110f0db4f5dfcdfa600cc 333 SUPERFAMILY SSF53474 50 327 3.34E-15 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_20285 0ff101873b4110f0db4f5dfcdfa600cc 333 PIRSF PIRSF031982 1 333 2.1E-60 T 14-10-2018 IPR016986 Uncharacterised conserved protein UCP031982, alpha/beta hydrolase, XabL TSH58p_22355 8e53bb8cadec3050a3f4521e94fe8d75 164 SUPERFAMILY SSF50249 1 164 1.59E-32 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_22355 8e53bb8cadec3050a3f4521e94fe8d75 164 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 6 164 1.7E-19 T 14-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 TSH58p_22355 8e53bb8cadec3050a3f4521e94fe8d75 164 Pfam PF00436 Single-strand binding protein family 1 98 5.8E-18 T 14-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 TSH58p_22355 8e53bb8cadec3050a3f4521e94fe8d75 164 Gene3D G3DSA:2.40.50.140 1 125 2.3E-26 T 14-10-2018 TSH58p_14580 db3b3fbcc326cbfc456caa09e4cefa4d 410 SUPERFAMILY SSF47090 73 146 5.23E-14 T 14-10-2018 IPR036365 PGBD-like superfamily TSH58p_14580 db3b3fbcc326cbfc456caa09e4cefa4d 410 Pfam PF03734 L,D-transpeptidase catalytic domain 168 330 8.3E-26 T 14-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 TSH58p_14580 db3b3fbcc326cbfc456caa09e4cefa4d 410 Gene3D G3DSA:2.40.440.10 109 331 5.3E-31 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like TSH58p_14580 db3b3fbcc326cbfc456caa09e4cefa4d 410 Pfam PF01471 Putative peptidoglycan binding domain 84 140 3.6E-8 T 14-10-2018 IPR002477 Peptidoglycan binding-like TSH58p_14580 db3b3fbcc326cbfc456caa09e4cefa4d 410 SUPERFAMILY SSF141523 166 321 1.7E-21 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like TSH58p_02890 9f6b017462050e27e3df783b7b6eddb8 397 SMART SM00710 266 288 820.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_02890 9f6b017462050e27e3df783b7b6eddb8 397 SMART SM00710 188 209 4500.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_02890 9f6b017462050e27e3df783b7b6eddb8 397 SMART SM00710 212 233 800.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_02890 9f6b017462050e27e3df783b7b6eddb8 397 SMART SM00710 235 259 820.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_02890 9f6b017462050e27e3df783b7b6eddb8 397 SMART SM00710 112 134 1400.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_02890 9f6b017462050e27e3df783b7b6eddb8 397 SMART SM00710 155 176 940.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_02890 9f6b017462050e27e3df783b7b6eddb8 397 SUPERFAMILY SSF51126 77 315 1.71E-21 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor TSH58p_02890 9f6b017462050e27e3df783b7b6eddb8 397 Gene3D G3DSA:2.160.20.10 79 327 1.9E-26 T 14-10-2018 IPR012334 Pectin lyase fold TSH58p_02890 9f6b017462050e27e3df783b7b6eddb8 397 Pfam PF13229 Right handed beta helix region 115 276 7.6E-16 T 14-10-2018 IPR039448 Right handed beta helix domain TSH58p_02890 9f6b017462050e27e3df783b7b6eddb8 397 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 217 249 6.7E-5 T 14-10-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 TSH58p_23110 fe47e54744cdfbd5660f1eb949aa0c23 544 SMART SM00388 331 399 5.8E-19 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_23110 fe47e54744cdfbd5660f1eb949aa0c23 544 Pfam PF00512 His Kinase A (phospho-acceptor) domain 333 397 1.7E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_23110 fe47e54744cdfbd5660f1eb949aa0c23 544 PRINTS PR00344 Bacterial sensor protein C-terminal signature 471 485 3.8E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_23110 fe47e54744cdfbd5660f1eb949aa0c23 544 PRINTS PR00344 Bacterial sensor protein C-terminal signature 502 520 3.8E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_23110 fe47e54744cdfbd5660f1eb949aa0c23 544 PRINTS PR00344 Bacterial sensor protein C-terminal signature 489 499 3.8E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_23110 fe47e54744cdfbd5660f1eb949aa0c23 544 SUPERFAMILY SSF47384 314 397 3.92E-19 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_23110 fe47e54744cdfbd5660f1eb949aa0c23 544 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 438 537 5.0E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_23110 fe47e54744cdfbd5660f1eb949aa0c23 544 SMART SM00387 434 541 2.4E-30 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_23110 fe47e54744cdfbd5660f1eb949aa0c23 544 Gene3D G3DSA:1.10.287.130 275 395 1.6E-21 T 14-10-2018 TSH58p_23110 fe47e54744cdfbd5660f1eb949aa0c23 544 SUPERFAMILY SSF55874 403 537 5.89E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_23110 fe47e54744cdfbd5660f1eb949aa0c23 544 Gene3D G3DSA:3.30.565.10 397 542 1.0E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_19015 134da16787c801f487c4f6a3f2dd6f25 144 Pfam PF09722 Protein of unknown function (DUF2384) 92 141 4.9E-14 T 14-10-2018 IPR024467 Domain of unknown function DUF2384 TSH58p_19015 134da16787c801f487c4f6a3f2dd6f25 144 TIGRFAM TIGR02293 TAS_TIGR02293: putative toxin-antitoxin system antitoxin component, TIGR02293 family 15 142 8.5E-25 T 14-10-2018 IPR011979 Conserved hypothetical protein CHP02293 TSH58p_25810 f29272e2c160b6ec4f36b39a18ab5e43 463 TIGRFAM TIGR00937 2A51: chromate efflux transporter 30 432 1.1E-60 T 14-10-2018 IPR014047 Chromate transporter, long chain TSH58p_25810 f29272e2c160b6ec4f36b39a18ab5e43 463 Pfam PF02417 Chromate transporter 260 454 3.0E-32 T 14-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 TSH58p_25810 f29272e2c160b6ec4f36b39a18ab5e43 463 Pfam PF02417 Chromate transporter 23 186 1.9E-32 T 14-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 TSH58p_25810 f29272e2c160b6ec4f36b39a18ab5e43 463 PIRSF PIRSF004810 3 461 2.1E-131 T 14-10-2018 IPR014047 Chromate transporter, long chain TSH58p_04335 16b1274addca48b2353ba8cdc99a7be0 213 SUPERFAMILY SSF55729 65 192 1.98E-17 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_04335 16b1274addca48b2353ba8cdc99a7be0 213 Gene3D G3DSA:3.40.630.30 29 192 5.5E-14 T 14-10-2018 TSH58p_04335 16b1274addca48b2353ba8cdc99a7be0 213 Pfam PF00583 Acetyltransferase (GNAT) family 75 182 2.7E-7 T 14-10-2018 IPR000182 GNAT domain TSH58p_31065 79fb13c6ecc24cebac4c1763b9735a6b 298 Gene3D G3DSA:1.10.10.10 6 95 3.0E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_31065 79fb13c6ecc24cebac4c1763b9735a6b 298 SUPERFAMILY SSF53850 92 295 5.74E-35 T 14-10-2018 TSH58p_31065 79fb13c6ecc24cebac4c1763b9735a6b 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 1.0E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_31065 79fb13c6ecc24cebac4c1763b9735a6b 298 SUPERFAMILY SSF46785 2 80 7.07E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_31065 79fb13c6ecc24cebac4c1763b9735a6b 298 Pfam PF03466 LysR substrate binding domain 92 291 3.7E-36 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_31065 79fb13c6ecc24cebac4c1763b9735a6b 298 Gene3D G3DSA:3.40.190.10 102 290 1.2E-43 T 14-10-2018 TSH58p_31065 79fb13c6ecc24cebac4c1763b9735a6b 298 Gene3D G3DSA:3.40.190.10 165 264 1.2E-43 T 14-10-2018 TSH58p_29580 b29eaf366c89e08dbe54b65f86069a08 139 SUPERFAMILY SSF47598 14 57 4.0E-8 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TSH58p_06780 11b91e13bb837875f80c63c6913bdb35 406 SUPERFAMILY SSF51713 4 359 1.44E-153 T 14-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TSH58p_06780 11b91e13bb837875f80c63c6913bdb35 406 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 360 4.8E-145 T 14-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TSH58p_06780 11b91e13bb837875f80c63c6913bdb35 406 Gene3D G3DSA:3.20.20.105 1 369 9.4E-164 T 14-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TSH58p_06780 11b91e13bb837875f80c63c6913bdb35 406 Pfam PF01702 Queuine tRNA-ribosyltransferase 130 359 1.1E-85 T 14-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TSH58p_06780 11b91e13bb837875f80c63c6913bdb35 406 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 4 366 54.069 T 14-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TSH58p_06780 11b91e13bb837875f80c63c6913bdb35 406 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 6 366 2.7E-149 T 14-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TSH58p_00845 e7981dd34b0929c0b86094a6a1096af7 330 SMART SM00342 230 313 3.2E-27 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TSH58p_00845 e7981dd34b0929c0b86094a6a1096af7 330 Pfam PF12852 Cupin 9 197 4.6E-33 T 14-10-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain TSH58p_00845 e7981dd34b0929c0b86094a6a1096af7 330 Gene3D G3DSA:1.10.10.60 209 319 1.1E-24 T 14-10-2018 TSH58p_00845 e7981dd34b0929c0b86094a6a1096af7 330 SUPERFAMILY SSF46689 266 315 3.05E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_00845 e7981dd34b0929c0b86094a6a1096af7 330 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 267 309 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 TSH58p_00845 e7981dd34b0929c0b86094a6a1096af7 330 Pfam PF12833 Helix-turn-helix domain 236 314 2.0E-19 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TSH58p_00845 e7981dd34b0929c0b86094a6a1096af7 330 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 282 297 1.2E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TSH58p_00845 e7981dd34b0929c0b86094a6a1096af7 330 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 297 313 1.2E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TSH58p_00845 e7981dd34b0929c0b86094a6a1096af7 330 SUPERFAMILY SSF46689 216 264 2.51E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_26125 5d541bfc5a63bf7f164cda3e09c113ae 108 Pfam PF09981 Uncharacterized protein conserved in bacteria (DUF2218) 8 103 9.9E-32 T 14-10-2018 IPR014543 Uncharacterised conserved protein UCP028291 TSH58p_26125 5d541bfc5a63bf7f164cda3e09c113ae 108 PIRSF PIRSF028291 1 108 2.1E-23 T 14-10-2018 IPR014543 Uncharacterised conserved protein UCP028291 TSH58p_26125 5d541bfc5a63bf7f164cda3e09c113ae 108 Gene3D G3DSA:3.30.310.50 3 107 3.2E-29 T 14-10-2018 TSH58p_17885 3ef09e2f2076889df474e735c44907dc 324 Pfam PF13641 Glycosyltransferase like family 2 5 246 1.3E-16 T 14-10-2018 TSH58p_17885 3ef09e2f2076889df474e735c44907dc 324 SUPERFAMILY SSF53448 3 270 7.03E-43 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_17885 3ef09e2f2076889df474e735c44907dc 324 Gene3D G3DSA:3.90.550.10 1 252 5.6E-38 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_31380 1edd9c61b6beba397aa8915fe36e2741 78 SUPERFAMILY SSF89447 2 42 9.94E-11 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily TSH58p_31380 1edd9c61b6beba397aa8915fe36e2741 78 Gene3D G3DSA:2.10.260.10 2 41 1.7E-12 T 14-10-2018 TSH58p_31380 1edd9c61b6beba397aa8915fe36e2741 78 Pfam PF15937 prlF antitoxin for toxin YhaV_toxin 3 46 8.3E-10 T 14-10-2018 IPR031848 PrlF antitoxin GO:0001558|GO:0003700|GO:0097351 TSH58p_31380 1edd9c61b6beba397aa8915fe36e2741 78 SMART SM00966 3 49 5.7E-12 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TSH58p_31380 1edd9c61b6beba397aa8915fe36e2741 78 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 3 44 1.7E-15 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TSH58p_13950 a35d7386450d4b6e2ab17680e45adb98 207 Hamap MF_01658 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase [coq7]. 7 207 28.493 T 14-10-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 TSH58p_13950 a35d7386450d4b6e2ab17680e45adb98 207 SUPERFAMILY SSF47240 43 174 5.62E-18 T 14-10-2018 IPR009078 Ferritin-like superfamily TSH58p_13950 a35d7386450d4b6e2ab17680e45adb98 207 Pfam PF03232 Ubiquinone biosynthesis protein COQ7 43 207 2.7E-65 T 14-10-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 TSH58p_02600 b9c5f100d8fbec95dc265f4ed33f8c88 424 SUPERFAMILY SSF47384 196 263 7.85E-7 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_02600 b9c5f100d8fbec95dc265f4ed33f8c88 424 Gene3D G3DSA:3.30.565.10 271 414 2.4E-22 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_02600 b9c5f100d8fbec95dc265f4ed33f8c88 424 SMART SM00388 201 268 0.01 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_02600 b9c5f100d8fbec95dc265f4ed33f8c88 424 Gene3D G3DSA:1.10.287.130 178 262 8.0E-7 T 14-10-2018 TSH58p_02600 b9c5f100d8fbec95dc265f4ed33f8c88 424 SMART SM00387 310 415 1.5E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_02600 b9c5f100d8fbec95dc265f4ed33f8c88 424 SUPERFAMILY SSF55874 277 415 1.23E-23 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_02600 b9c5f100d8fbec95dc265f4ed33f8c88 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 345 359 3.0E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_02600 b9c5f100d8fbec95dc265f4ed33f8c88 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 393 3.0E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_02600 b9c5f100d8fbec95dc265f4ed33f8c88 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 412 3.0E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_02600 b9c5f100d8fbec95dc265f4ed33f8c88 424 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 314 414 7.2E-14 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_31550 7d98efad6a3fb6893a30f45504ee76e0 484 SUPERFAMILY SSF51556 52 370 1.95E-53 T 14-10-2018 IPR032466 Metal-dependent hydrolase TSH58p_31550 7d98efad6a3fb6893a30f45504ee76e0 484 Gene3D G3DSA:2.30.40.10 24 437 9.6E-73 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_31550 7d98efad6a3fb6893a30f45504ee76e0 484 Gene3D G3DSA:3.20.20.140 54 377 9.6E-73 T 14-10-2018 TSH58p_31550 7d98efad6a3fb6893a30f45504ee76e0 484 Pfam PF01979 Amidohydrolase family 50 431 5.6E-34 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TSH58p_31550 7d98efad6a3fb6893a30f45504ee76e0 484 SUPERFAMILY SSF51338 22 451 2.49E-8 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_31565 4fecdfca8bec28f4b7250645e88e060a 484 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 31 442 6.7E-100 T 14-10-2018 TSH58p_31565 4fecdfca8bec28f4b7250645e88e060a 484 ProSitePatterns PS00482 Dihydroorotase signature 1. 69 77 - T 14-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSH58p_31565 4fecdfca8bec28f4b7250645e88e060a 484 ProSitePatterns PS00483 Dihydroorotase signature 2. 319 330 - T 14-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSH58p_31565 4fecdfca8bec28f4b7250645e88e060a 484 Gene3D G3DSA:2.30.40.10 16 453 1.1E-155 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_31565 4fecdfca8bec28f4b7250645e88e060a 484 SUPERFAMILY SSF51338 13 448 1.37E-29 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_31565 4fecdfca8bec28f4b7250645e88e060a 484 TIGRFAM TIGR03178 allantoinase: allantoinase 14 452 8.4E-108 T 14-10-2018 IPR017593 Allantoinase GO:0000256|GO:0004038|GO:0008270|GO:0050897 KEGG: 00230+3.5.2.5|MetaCyc: PWY-5697|MetaCyc: PWY-5698 TSH58p_31565 4fecdfca8bec28f4b7250645e88e060a 484 SUPERFAMILY SSF51556 66 385 4.23E-105 T 14-10-2018 IPR032466 Metal-dependent hydrolase TSH58p_31565 4fecdfca8bec28f4b7250645e88e060a 484 Pfam PF01979 Amidohydrolase family 63 437 3.0E-32 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TSH58p_31565 4fecdfca8bec28f4b7250645e88e060a 484 Gene3D G3DSA:3.20.20.140 66 381 1.1E-155 T 14-10-2018 TSH58p_14550 b92cc3db692cc9051bcbb511dcde7850 393 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 26 142 1.8E-15 T 14-10-2018 IPR000014 PAS domain TSH58p_14550 b92cc3db692cc9051bcbb511dcde7850 393 SMART SM00387 277 389 2.4E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_14550 b92cc3db692cc9051bcbb511dcde7850 393 SUPERFAMILY SSF55874 223 385 1.17E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_14550 b92cc3db692cc9051bcbb511dcde7850 393 Gene3D G3DSA:1.10.287.130 134 229 2.7E-8 T 14-10-2018 TSH58p_14550 b92cc3db692cc9051bcbb511dcde7850 393 SUPERFAMILY SSF47384 146 233 1.02E-8 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_14550 b92cc3db692cc9051bcbb511dcde7850 393 Gene3D G3DSA:3.30.565.10 230 387 3.9E-33 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_14550 b92cc3db692cc9051bcbb511dcde7850 393 Pfam PF00989 PAS fold 26 134 3.3E-9 T 14-10-2018 IPR013767 PAS fold GO:0006355 TSH58p_14550 b92cc3db692cc9051bcbb511dcde7850 393 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 278 386 6.3E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_14550 b92cc3db692cc9051bcbb511dcde7850 393 SMART SM00091 23 88 5.9E-7 T 14-10-2018 IPR000014 PAS domain TSH58p_14550 b92cc3db692cc9051bcbb511dcde7850 393 SUPERFAMILY SSF55785 23 135 1.03E-14 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_14550 b92cc3db692cc9051bcbb511dcde7850 393 Gene3D G3DSA:3.30.450.20 21 133 1.3E-13 T 14-10-2018 TSH58p_22315 d572bcacb6c2c01287148fb927350c1a 634 Pfam PF12532 Protein of unknown function (DUF3732) 452 627 1.5E-51 T 14-10-2018 IPR022205 Protein of unknown function DUF3732 TSH58p_07025 a650cb7c4adf9004f810e969243f436e 129 Pfam PF06803 Protein of unknown function (DUF1232) 32 68 7.4E-14 T 14-10-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 TSH58p_10650 2eba07ca45a8b8ccdef2d1bcf71862c8 326 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 124 296 2.0E-73 T 14-10-2018 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 TSH58p_10650 2eba07ca45a8b8ccdef2d1bcf71862c8 326 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 3 120 2.2E-44 T 14-10-2018 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 TSH58p_10650 2eba07ca45a8b8ccdef2d1bcf71862c8 326 Hamap MF_00162 Glutathione synthetase [gshB]. 1 316 157.15 T 14-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 TSH58p_10650 2eba07ca45a8b8ccdef2d1bcf71862c8 326 SUPERFAMILY SSF52440 3 122 6.04E-43 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TSH58p_10650 2eba07ca45a8b8ccdef2d1bcf71862c8 326 Gene3D G3DSA:3.30.470.20 115 294 8.1E-115 T 14-10-2018 TSH58p_10650 2eba07ca45a8b8ccdef2d1bcf71862c8 326 Gene3D G3DSA:3.40.50.20 9 114 8.1E-115 T 14-10-2018 TSH58p_10650 2eba07ca45a8b8ccdef2d1bcf71862c8 326 SUPERFAMILY SSF56059 124 311 3.53E-56 T 14-10-2018 TSH58p_10650 2eba07ca45a8b8ccdef2d1bcf71862c8 326 Gene3D G3DSA:3.30.1490.20 137 201 8.1E-115 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSH58p_10650 2eba07ca45a8b8ccdef2d1bcf71862c8 326 TIGRFAM TIGR01380 glut_syn: glutathione synthase 3 310 8.6E-126 T 14-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 TSH58p_04340 e301881d36ae1e1f0084b9b7352fcac3 144 SUPERFAMILY SSF55729 7 140 7.72E-27 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_04340 e301881d36ae1e1f0084b9b7352fcac3 144 Pfam PF00583 Acetyltransferase (GNAT) family 29 127 1.2E-13 T 14-10-2018 IPR000182 GNAT domain TSH58p_04340 e301881d36ae1e1f0084b9b7352fcac3 144 Gene3D G3DSA:3.40.630.30 6 142 1.8E-34 T 14-10-2018 TSH58p_11725 851d23e501255f0462a0c1a9e6b8f8e2 319 Gene3D G3DSA:3.40.50.1100 54 156 2.2E-122 T 14-10-2018 TSH58p_11725 851d23e501255f0462a0c1a9e6b8f8e2 319 Gene3D G3DSA:3.40.50.1100 17 310 2.2E-122 T 14-10-2018 TSH58p_11725 851d23e501255f0462a0c1a9e6b8f8e2 319 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 16 303 2.4E-64 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TSH58p_11725 851d23e501255f0462a0c1a9e6b8f8e2 319 TIGRFAM TIGR01139 cysK: cysteine synthase A 15 315 3.1E-134 T 14-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 TSH58p_11725 851d23e501255f0462a0c1a9e6b8f8e2 319 SUPERFAMILY SSF53686 9 315 5.11E-99 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TSH58p_11725 851d23e501255f0462a0c1a9e6b8f8e2 319 TIGRFAM TIGR01136 cysKM: cysteine synthase 15 315 7.8E-129 T 14-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 TSH58p_09845 3c04c51e37832bffdaaf97b16687add3 323 Gene3D G3DSA:3.40.190.10 126 249 2.4E-81 T 14-10-2018 TSH58p_09845 3c04c51e37832bffdaaf97b16687add3 323 Gene3D G3DSA:3.40.190.150 28 306 2.4E-81 T 14-10-2018 TSH58p_09845 3c04c51e37832bffdaaf97b16687add3 323 PIRSF PIRSF017082 1 323 3.9E-90 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 TSH58p_09845 3c04c51e37832bffdaaf97b16687add3 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 287 5.8E-49 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 TSH58p_30490 92f8e78974c4ef1b9c5fb2592fcec56c 283 PIRSF PIRSF015582 2 283 5.1E-83 T 14-10-2018 IPR011206 Citrate lyase beta subunit-like TSH58p_30490 92f8e78974c4ef1b9c5fb2592fcec56c 283 SUPERFAMILY SSF51621 7 233 3.28E-63 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSH58p_30490 92f8e78974c4ef1b9c5fb2592fcec56c 283 Gene3D G3DSA:3.20.20.60 2 283 6.2E-88 T 14-10-2018 TSH58p_30490 92f8e78974c4ef1b9c5fb2592fcec56c 283 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 10 222 3.5E-45 T 14-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 TSH58p_18920 2f255b172d5f20994dd3625bc777ba84 386 Gene3D G3DSA:2.120.10.30 30 383 5.9E-135 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TSH58p_18920 2f255b172d5f20994dd3625bc777ba84 386 Pfam PF07995 Glucose / Sorbosone dehydrogenase 45 379 8.0E-146 T 14-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase TSH58p_18920 2f255b172d5f20994dd3625bc777ba84 386 SUPERFAMILY SSF50952 38 384 1.1E-51 T 14-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 TSH58p_21250 003a0eb89cd06f5ddb551ef8b1d9215b 473 Pfam PF13500 AAA domain 267 457 8.0E-57 T 14-10-2018 TSH58p_21250 003a0eb89cd06f5ddb551ef8b1d9215b 473 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 269 424 8.3E-42 T 14-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 TSH58p_21250 003a0eb89cd06f5ddb551ef8b1d9215b 473 Pfam PF08242 Methyltransferase domain 51 148 1.9E-16 T 14-10-2018 IPR013217 Methyltransferase type 12 TSH58p_21250 003a0eb89cd06f5ddb551ef8b1d9215b 473 SUPERFAMILY SSF52540 267 462 1.28E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_21250 003a0eb89cd06f5ddb551ef8b1d9215b 473 Gene3D G3DSA:3.40.50.300 265 465 7.3E-54 T 14-10-2018 TSH58p_21250 003a0eb89cd06f5ddb551ef8b1d9215b 473 Gene3D G3DSA:3.40.50.150 10 176 1.4E-34 T 14-10-2018 TSH58p_21250 003a0eb89cd06f5ddb551ef8b1d9215b 473 SUPERFAMILY SSF53335 10 260 2.74E-34 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_21250 003a0eb89cd06f5ddb551ef8b1d9215b 473 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 265 463 27.907 T 14-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 TSH58p_21615 f9ce6d3b825d5356098560bd21ff14a4 369 Pfam PF00990 Diguanylate cyclase, GGDEF domain 209 363 1.8E-46 T 14-10-2018 IPR000160 GGDEF domain TSH58p_21615 f9ce6d3b825d5356098560bd21ff14a4 369 SMART SM00267 197 367 3.3E-63 T 14-10-2018 IPR000160 GGDEF domain TSH58p_21615 f9ce6d3b825d5356098560bd21ff14a4 369 Gene3D G3DSA:3.30.450.20 82 205 9.8E-24 T 14-10-2018 TSH58p_21615 f9ce6d3b825d5356098560bd21ff14a4 369 SUPERFAMILY SSF55073 213 365 1.49E-50 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_21615 f9ce6d3b825d5356098560bd21ff14a4 369 SMART SM00086 155 197 0.0099 T 14-10-2018 IPR001610 PAC motif TSH58p_21615 f9ce6d3b825d5356098560bd21ff14a4 369 SMART SM00091 84 151 4.1E-8 T 14-10-2018 IPR000014 PAS domain TSH58p_21615 f9ce6d3b825d5356098560bd21ff14a4 369 Gene3D G3DSA:3.30.70.270 206 367 4.7E-60 T 14-10-2018 TSH58p_21615 f9ce6d3b825d5356098560bd21ff14a4 369 Pfam PF00989 PAS fold 85 193 1.6E-14 T 14-10-2018 IPR013767 PAS fold GO:0006355 TSH58p_21615 f9ce6d3b825d5356098560bd21ff14a4 369 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 81 204 5.4E-21 T 14-10-2018 IPR000014 PAS domain TSH58p_21615 f9ce6d3b825d5356098560bd21ff14a4 369 SUPERFAMILY SSF55785 72 195 4.51E-23 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_21615 f9ce6d3b825d5356098560bd21ff14a4 369 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 206 365 1.1E-43 T 14-10-2018 IPR000160 GGDEF domain TSH58p_27215 309416990f57d1498aff4bbf2b8364aa 335 Pfam PF01384 Phosphate transporter family 25 323 7.0E-89 T 14-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 TSH58p_03785 bea4c686a4c4093b8bdc21450a204a21 100 Pfam PF11011 Protein of unknown function (DUF2849) 3 92 3.8E-25 T 14-10-2018 IPR021270 Protein of unknown function DUF2849 TSH58p_04010 18f4048b1d1af46502baa00dc7c192c0 258 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 21 255 4.5E-76 T 14-10-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria TSH58p_04010 18f4048b1d1af46502baa00dc7c192c0 258 Pfam PF02405 Permease MlaE 42 251 9.1E-81 T 14-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 TSH58p_32350 67bb7bb933d1ce0e1ce4ee127ac7f0bd 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 255 1.0E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_32350 67bb7bb933d1ce0e1ce4ee127ac7f0bd 266 Gene3D G3DSA:1.10.3720.10 6 263 1.2E-56 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_32350 67bb7bb933d1ce0e1ce4ee127ac7f0bd 266 SUPERFAMILY SSF161098 7 253 2.35E-58 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_04880 5ec8caf0bda2936fcc70d99e11758995 234 Pfam PF01895 PhoU domain 22 108 3.3E-21 T 14-10-2018 IPR026022 PhoU domain TSH58p_04880 5ec8caf0bda2936fcc70d99e11758995 234 Pfam PF01895 PhoU domain 126 208 1.8E-16 T 14-10-2018 IPR026022 PhoU domain TSH58p_04880 5ec8caf0bda2936fcc70d99e11758995 234 Gene3D G3DSA:1.20.58.220 8 218 4.4E-68 T 14-10-2018 IPR038078 PhoU-like domain superfamily TSH58p_04880 5ec8caf0bda2936fcc70d99e11758995 234 SUPERFAMILY SSF109755 9 224 3.66E-65 T 14-10-2018 TSH58p_04880 5ec8caf0bda2936fcc70d99e11758995 234 PIRSF PIRSF003107 4 222 6.6E-64 T 14-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 TSH58p_04880 5ec8caf0bda2936fcc70d99e11758995 234 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 9 216 1.8E-64 T 14-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 TSH58p_07020 016fcb7481827e68d32107b44dd620f3 441 Gene3D G3DSA:1.10.8.350 76 237 1.2E-84 T 14-10-2018 TSH58p_07020 016fcb7481827e68d32107b44dd620f3 441 Gene3D G3DSA:1.10.530.10 104 353 1.2E-84 T 14-10-2018 TSH58p_07020 016fcb7481827e68d32107b44dd620f3 441 SUPERFAMILY SSF53955 49 359 1.39E-96 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily TSH58p_07020 016fcb7481827e68d32107b44dd620f3 441 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 61 358 7.7E-114 T 14-10-2018 IPR011970 Lytic murein transglycosylase TSH58p_07020 016fcb7481827e68d32107b44dd620f3 441 Pfam PF13406 Transglycosylase SLT domain 62 354 2.9E-108 T 14-10-2018 IPR031304 Transglycosylase SLT domain 2 TSH58p_07020 016fcb7481827e68d32107b44dd620f3 441 SUPERFAMILY SSF47090 363 434 2.15E-17 T 14-10-2018 IPR036365 PGBD-like superfamily TSH58p_07020 016fcb7481827e68d32107b44dd620f3 441 Gene3D G3DSA:1.10.101.10 373 436 2.7E-12 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 TSH58p_07020 016fcb7481827e68d32107b44dd620f3 441 Pfam PF01471 Putative peptidoglycan binding domain 375 430 1.8E-10 T 14-10-2018 IPR002477 Peptidoglycan binding-like TSH58p_01880 91dfd921c7eaa4fba08aa0c9555580fc 394 SMART SM00116 267 315 0.0068 T 14-10-2018 IPR000644 CBS domain TSH58p_01880 91dfd921c7eaa4fba08aa0c9555580fc 394 SMART SM00116 323 371 0.27 T 14-10-2018 IPR000644 CBS domain TSH58p_01880 91dfd921c7eaa4fba08aa0c9555580fc 394 Pfam PF00571 CBS domain 261 310 2.5E-6 T 14-10-2018 IPR000644 CBS domain TSH58p_01880 91dfd921c7eaa4fba08aa0c9555580fc 394 Pfam PF00571 CBS domain 317 370 2.3E-5 T 14-10-2018 IPR000644 CBS domain TSH58p_01880 91dfd921c7eaa4fba08aa0c9555580fc 394 Gene3D G3DSA:3.10.580.10 227 310 2.6E-9 T 14-10-2018 TSH58p_01880 91dfd921c7eaa4fba08aa0c9555580fc 394 Pfam PF04982 HPP family 72 192 1.4E-37 T 14-10-2018 IPR007065 HPP TSH58p_01880 91dfd921c7eaa4fba08aa0c9555580fc 394 SUPERFAMILY SSF54631 250 369 5.75E-21 T 14-10-2018 TSH58p_01880 91dfd921c7eaa4fba08aa0c9555580fc 394 Gene3D G3DSA:3.10.580.10 311 381 7.1E-7 T 14-10-2018 TSH58p_19540 fb643f4196d820ca87059a817cc53774 254 Pfam PF00440 Bacterial regulatory proteins, tetR family 45 91 4.9E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_19540 fb643f4196d820ca87059a817cc53774 254 SUPERFAMILY SSF46689 34 109 1.08E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_19540 fb643f4196d820ca87059a817cc53774 254 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 66 89 2.4E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_19540 fb643f4196d820ca87059a817cc53774 254 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 58 2.4E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_19540 fb643f4196d820ca87059a817cc53774 254 Gene3D G3DSA:1.10.357.10 43 241 1.4E-64 T 14-10-2018 TSH58p_19540 fb643f4196d820ca87059a817cc53774 254 SUPERFAMILY SSF48498 116 243 3.07E-30 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TSH58p_19540 fb643f4196d820ca87059a817cc53774 254 ProSitePatterns PS01081 TetR-type HTH domain signature. 57 87 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site TSH58p_24115 f1fc99d85abf673f31091b3e2eba4029 481 Gene3D G3DSA:1.10.10.10 15 89 7.3E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_24115 f1fc99d85abf673f31091b3e2eba4029 481 Gene3D G3DSA:3.40.640.10 108 472 2.8E-98 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_24115 f1fc99d85abf673f31091b3e2eba4029 481 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 59 6.3E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_24115 f1fc99d85abf673f31091b3e2eba4029 481 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 59 75 6.3E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_24115 f1fc99d85abf673f31091b3e2eba4029 481 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 85 9.3E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_24115 f1fc99d85abf673f31091b3e2eba4029 481 SUPERFAMILY SSF46785 15 89 1.17E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_24115 f1fc99d85abf673f31091b3e2eba4029 481 Pfam PF00155 Aminotransferase class I and II 150 394 7.9E-18 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSH58p_24115 f1fc99d85abf673f31091b3e2eba4029 481 SMART SM00345 26 85 4.3E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_24115 f1fc99d85abf673f31091b3e2eba4029 481 SUPERFAMILY SSF53383 112 479 1.68E-74 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_18735 e4b590979f7a6456e59f8ccb31c53611 394 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 21 372 1.5E-109 T 14-10-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 KEGG: 00730+1.4.3.19|MetaCyc: PWY-7396|MetaCyc: PWY-7806 TSH58p_18735 e4b590979f7a6456e59f8ccb31c53611 394 Gene3D G3DSA:3.50.50.60 21 369 4.5E-102 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_18735 e4b590979f7a6456e59f8ccb31c53611 394 SUPERFAMILY SSF51905 19 386 3.88E-52 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_18735 e4b590979f7a6456e59f8ccb31c53611 394 SUPERFAMILY SSF54373 241 329 1.11E-21 T 14-10-2018 TSH58p_18735 e4b590979f7a6456e59f8ccb31c53611 394 Pfam PF01266 FAD dependent oxidoreductase 21 367 4.6E-71 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TSH58p_18735 e4b590979f7a6456e59f8ccb31c53611 394 Gene3D G3DSA:3.30.9.10 107 329 4.5E-102 T 14-10-2018 TSH58p_14975 59ad70aafbf853cf6ba10c5ecbf975f2 304 Gene3D G3DSA:3.30.420.40 9 298 1.4E-81 T 14-10-2018 TSH58p_14975 59ad70aafbf853cf6ba10c5ecbf975f2 304 ProSitePatterns PS01125 ROK family signature. 135 162 - T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TSH58p_14975 59ad70aafbf853cf6ba10c5ecbf975f2 304 Pfam PF00480 ROK family 8 303 2.6E-70 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TSH58p_14975 59ad70aafbf853cf6ba10c5ecbf975f2 304 SUPERFAMILY SSF53067 6 301 7.04E-63 T 14-10-2018 TSH58p_14975 59ad70aafbf853cf6ba10c5ecbf975f2 304 Gene3D G3DSA:3.30.420.40 124 291 1.4E-81 T 14-10-2018 TSH58p_14205 f6b506149ca81e7f872756464438e02a 368 SMART SM00228 145 220 9.7E-7 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_14205 f6b506149ca81e7f872756464438e02a 368 Gene3D G3DSA:2.30.42.10 137 231 2.3E-16 T 14-10-2018 TSH58p_14205 f6b506149ca81e7f872756464438e02a 368 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 159 215 2.6E-6 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_14205 f6b506149ca81e7f872756464438e02a 368 SUPERFAMILY SSF50156 138 222 1.16E-14 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 TSH58p_04320 b756707c5b9f7b55564d7053bf4771bf 258 Gene3D G3DSA:3.40.50.300 14 258 1.1E-78 T 14-10-2018 TSH58p_04320 b756707c5b9f7b55564d7053bf4771bf 258 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_04320 b756707c5b9f7b55564d7053bf4771bf 258 SMART SM00382 42 229 2.9E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_04320 b756707c5b9f7b55564d7053bf4771bf 258 SUPERFAMILY SSF52540 17 251 6.49E-82 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_04320 b756707c5b9f7b55564d7053bf4771bf 258 Pfam PF00005 ABC transporter 33 181 1.7E-37 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_04320 b756707c5b9f7b55564d7053bf4771bf 258 PIRSF PIRSF039085 14 257 3.4E-110 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 TSH58p_19680 4157503ec9df22dd92e04bb6632a27b2 329 SUPERFAMILY SSF53850 38 287 1.52E-9 T 14-10-2018 TSH58p_19680 4157503ec9df22dd92e04bb6632a27b2 329 Gene3D G3DSA:3.40.190.10 126 248 3.7E-69 T 14-10-2018 TSH58p_19680 4157503ec9df22dd92e04bb6632a27b2 329 PIRSF PIRSF017082 1 321 1.3E-67 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 TSH58p_19680 4157503ec9df22dd92e04bb6632a27b2 329 Gene3D G3DSA:3.40.190.150 31 310 3.7E-69 T 14-10-2018 TSH58p_19680 4157503ec9df22dd92e04bb6632a27b2 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 287 9.8E-35 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 TSH58p_04825 5551aa88cf81c9c9e52b6145c1ee39be 505 Pfam PF02653 Branched-chain amino acid transport system / permease component 175 459 3.7E-45 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_04825 5551aa88cf81c9c9e52b6145c1ee39be 505 Pfam PF11862 Domain of unknown function (DUF3382) 17 76 1.6E-12 T 14-10-2018 IPR021807 High-affinity branched-chain amino acid transport system permease, LivHM, N-terminal TSH58p_16540 3381614b0cc4af28d06c4decc43d9407 162 Pfam PF02469 Fasciclin domain 38 161 3.3E-39 T 14-10-2018 IPR000782 FAS1 domain TSH58p_16540 3381614b0cc4af28d06c4decc43d9407 162 SMART SM00554 62 162 1.4E-36 T 14-10-2018 IPR000782 FAS1 domain TSH58p_16540 3381614b0cc4af28d06c4decc43d9407 162 Gene3D G3DSA:2.30.180.10 25 162 1.2E-51 T 14-10-2018 IPR036378 FAS1 domain superfamily TSH58p_16540 3381614b0cc4af28d06c4decc43d9407 162 SUPERFAMILY SSF82153 28 161 7.32E-44 T 14-10-2018 IPR036378 FAS1 domain superfamily TSH58p_14195 7967e72ac1d0c29b2aee86c397eb50b5 779 SUPERFAMILY SSF52540 32 661 2.89E-181 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_14195 7967e72ac1d0c29b2aee86c397eb50b5 779 Gene3D G3DSA:3.40.50.300 308 653 5.2E-110 T 14-10-2018 TSH58p_14195 7967e72ac1d0c29b2aee86c397eb50b5 779 Gene3D G3DSA:1.10.486.10 410 565 5.2E-110 T 14-10-2018 TSH58p_14195 7967e72ac1d0c29b2aee86c397eb50b5 779 Gene3D G3DSA:3.40.50.300 36 302 1.1E-95 T 14-10-2018 TSH58p_14195 7967e72ac1d0c29b2aee86c397eb50b5 779 Pfam PF00580 UvrD/REP helicase N-terminal domain 36 299 1.3E-73 T 14-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 TSH58p_14195 7967e72ac1d0c29b2aee86c397eb50b5 779 Pfam PF13361 UvrD-like helicase C-terminal domain 305 635 9.2E-63 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TSH58p_14195 7967e72ac1d0c29b2aee86c397eb50b5 779 Gene3D G3DSA:1.10.10.160 140 215 1.1E-95 T 14-10-2018 IPR013986 DExx box DNA helicase domain superfamily TSH58p_30795 1b3270f431b383825a8bf563914fc474 199 SUPERFAMILY SSF69118 24 194 2.44E-42 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TSH58p_30795 1b3270f431b383825a8bf563914fc474 199 TIGRFAM TIGR01926 peroxid_rel: uncharacterized peroxidase-related enzyme 29 193 9.3E-40 T 14-10-2018 IPR010195 Uncharacterised peroxidase-related TSH58p_30795 1b3270f431b383825a8bf563914fc474 199 Gene3D G3DSA:1.20.1290.10 76 199 1.1E-36 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TSH58p_30795 1b3270f431b383825a8bf563914fc474 199 Pfam PF02627 Carboxymuconolactone decarboxylase family 122 188 9.2E-7 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TSH58p_30795 1b3270f431b383825a8bf563914fc474 199 Pfam PF02627 Carboxymuconolactone decarboxylase family 63 107 1.9E-9 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TSH58p_30795 1b3270f431b383825a8bf563914fc474 199 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 75 107 2.8E-11 T 14-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TSH58p_10895 6db32438c5e6f20a2732e6b4996b9d18 332 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 325 2.0E-27 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_10895 6db32438c5e6f20a2732e6b4996b9d18 332 SUPERFAMILY SSF161098 98 308 4.91E-12 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_10895 6db32438c5e6f20a2732e6b4996b9d18 332 Gene3D G3DSA:1.10.3720.10 94 321 7.0E-14 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_22455 1888d6606364d1367640b9e11c1fee90 387 Gene3D G3DSA:3.30.70.270 218 386 4.0E-58 T 14-10-2018 TSH58p_22455 1888d6606364d1367640b9e11c1fee90 387 Pfam PF00990 Diguanylate cyclase, GGDEF domain 225 379 3.9E-45 T 14-10-2018 IPR000160 GGDEF domain TSH58p_22455 1888d6606364d1367640b9e11c1fee90 387 SMART SM00267 212 383 4.3E-60 T 14-10-2018 IPR000160 GGDEF domain TSH58p_22455 1888d6606364d1367640b9e11c1fee90 387 SUPERFAMILY SSF55073 228 383 8.63E-51 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_22455 1888d6606364d1367640b9e11c1fee90 387 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 220 383 3.8E-48 T 14-10-2018 IPR000160 GGDEF domain TSH58p_12845 f5094a25792b6495d3fb72c7ca007ff0 163 Gene3D G3DSA:1.10.3990.20 19 111 3.2E-14 T 14-10-2018 IPR038268 Ribbon-helix-helix domain superfamily TSH58p_12845 f5094a25792b6495d3fb72c7ca007ff0 163 Pfam PF13467 Ribbon-helix-helix domain 22 97 4.4E-27 T 14-10-2018 IPR027373 Ribbon-helix-helix domain TSH58p_20820 085eb7319f85bdb3f44514bb4df781c8 382 Gene3D G3DSA:3.20.20.80 17 354 4.6E-30 T 14-10-2018 TSH58p_20820 085eb7319f85bdb3f44514bb4df781c8 382 SUPERFAMILY SSF51445 9 352 1.15E-55 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_13630 271ae481aa6895f7d15038a31a6bf8bc 218 ProSitePatterns PS00958 Transaldolase active site. 80 97 - T 14-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 TSH58p_13630 271ae481aa6895f7d15038a31a6bf8bc 218 Hamap MF_00494 Probable transaldolase [tal]. 1 215 44.249 T 14-10-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TSH58p_13630 271ae481aa6895f7d15038a31a6bf8bc 218 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 212 2.7E-88 T 14-10-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TSH58p_13630 271ae481aa6895f7d15038a31a6bf8bc 218 Gene3D G3DSA:3.20.20.70 1 217 9.5E-89 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_13630 271ae481aa6895f7d15038a31a6bf8bc 218 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 213 4.6E-60 T 14-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 TSH58p_13630 271ae481aa6895f7d15038a31a6bf8bc 218 SUPERFAMILY SSF51569 1 216 3.66E-78 T 14-10-2018 TSH58p_13630 271ae481aa6895f7d15038a31a6bf8bc 218 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 14-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 TSH58p_27015 daef8126bf4b3522824a646619dbec28 522 SUPERFAMILY SSF53756 331 511 2.48E-13 T 14-10-2018 TSH58p_27015 daef8126bf4b3522824a646619dbec28 522 Pfam PF13692 Glycosyl transferases group 1 371 477 1.7E-7 T 14-10-2018 TSH58p_27015 daef8126bf4b3522824a646619dbec28 522 Gene3D G3DSA:3.40.50.2000 338 496 3.3E-20 T 14-10-2018 TSH58p_17460 28c7c145fe871d967967b5cbeea8e541 167 SMART SM00530 39 94 1.3E-11 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_17460 28c7c145fe871d967967b5cbeea8e541 167 Pfam PF01381 Helix-turn-helix 41 93 1.5E-11 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_17460 28c7c145fe871d967967b5cbeea8e541 167 SUPERFAMILY SSF47413 27 101 1.05E-26 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_17460 28c7c145fe871d967967b5cbeea8e541 167 Gene3D G3DSA:1.10.260.40 30 99 2.9E-15 T 14-10-2018 TSH58p_23400 290469c6e3dce132f2e3b8fdb06eff7f 130 Pfam PF14107 Domain of unknown function (DUF4280) 5 124 5.1E-31 T 14-10-2018 IPR025460 Protein of unknown function DUF4280 TSH58p_01550 28f29ccc2c2a6f7dbb80865d25816812 196 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 22 150 1.2E-27 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ TSH58p_23590 f37217ecc64e645cb05fbfd757e5aed5 492 Gene3D G3DSA:3.40.309.10 254 447 8.5E-183 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TSH58p_23590 f37217ecc64e645cb05fbfd757e5aed5 492 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 277 288 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 TSH58p_23590 f37217ecc64e645cb05fbfd757e5aed5 492 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 249 256 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 TSH58p_23590 f37217ecc64e645cb05fbfd757e5aed5 492 Pfam PF00171 Aldehyde dehydrogenase family 12 477 7.4E-176 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TSH58p_23590 f37217ecc64e645cb05fbfd757e5aed5 492 Gene3D G3DSA:3.40.605.10 8 475 8.5E-183 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TSH58p_23590 f37217ecc64e645cb05fbfd757e5aed5 492 SUPERFAMILY SSF53720 3 481 1.15E-170 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSH58p_14825 076498467b6c098d87be06152d388547 318 Gene3D G3DSA:3.40.50.1110 195 299 3.2E-5 T 14-10-2018 IPR036514 SGNH hydrolase superfamily TSH58p_14825 076498467b6c098d87be06152d388547 318 SUPERFAMILY SSF52266 47 292 5.04E-8 T 14-10-2018 TSH58p_10930 0c56e9605fb92cc5c3646c28bf8b8075 229 SMART SM00448 5 117 2.4E-36 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_10930 0c56e9605fb92cc5c3646c28bf8b8075 229 SUPERFAMILY SSF52172 5 161 3.56E-37 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_10930 0c56e9605fb92cc5c3646c28bf8b8075 229 SMART SM00862 152 227 1.2E-17 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_10930 0c56e9605fb92cc5c3646c28bf8b8075 229 Pfam PF00072 Response regulator receiver domain 7 117 1.0E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_10930 0c56e9605fb92cc5c3646c28bf8b8075 229 SUPERFAMILY SSF46894 126 228 1.63E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_10930 0c56e9605fb92cc5c3646c28bf8b8075 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 227 1.3E-20 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_10930 0c56e9605fb92cc5c3646c28bf8b8075 229 Gene3D G3DSA:1.10.10.10 131 229 6.0E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_10930 0c56e9605fb92cc5c3646c28bf8b8075 229 Gene3D G3DSA:3.40.50.2300 4 130 4.4E-33 T 14-10-2018 TSH58p_32085 fe44f0fe16413f7baa585a2552db65f3 236 Pfam PF13610 DDE domain 77 202 1.5E-28 T 14-10-2018 IPR032874 DDE domain TSH58p_08815 f8fcb81ca7930f10d36d9a594b68216a 256 PIRSF PIRSF004808 12 255 4.0E-75 T 14-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 TSH58p_08815 f8fcb81ca7930f10d36d9a594b68216a 256 Gene3D G3DSA:3.40.1280.10 13 175 1.6E-51 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TSH58p_08815 f8fcb81ca7930f10d36d9a594b68216a 256 Gene3D G3DSA:1.10.8.590 178 256 7.6E-11 T 14-10-2018 TSH58p_08815 f8fcb81ca7930f10d36d9a594b68216a 256 SUPERFAMILY SSF75217 16 172 2.62E-30 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases TSH58p_08815 f8fcb81ca7930f10d36d9a594b68216a 256 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 17 248 1.9E-50 T 14-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 TSH58p_08815 f8fcb81ca7930f10d36d9a594b68216a 256 Pfam PF00588 SpoU rRNA Methylase family 17 167 4.1E-27 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TSH58p_32240 ab9652334023056559cf4d83f08c7102 270 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 72 238 6.6E-29 T 14-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 TSH58p_02270 dae56d1e1a8db5b92774c51975ff40ac 29 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 6 29 3.5E-12 T 14-10-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 TSH58p_02270 dae56d1e1a8db5b92774c51975ff40ac 29 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 6 29 6.3E-12 T 14-10-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 TSH58p_11235 d0d78dfa0ad8d07358b276a7f460a685 265 SUPERFAMILY SSF51735 1 265 7.33E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_11235 d0d78dfa0ad8d07358b276a7f460a685 265 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 127 263 4.1E-41 T 14-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSH58p_11235 d0d78dfa0ad8d07358b276a7f460a685 265 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 149 166 - T 14-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSH58p_11235 d0d78dfa0ad8d07358b276a7f460a685 265 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 1 264 2.1E-80 T 14-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSH58p_11235 d0d78dfa0ad8d07358b276a7f460a685 265 PIRSF PIRSF000161 1 265 4.7E-80 T 14-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSH58p_11235 d0d78dfa0ad8d07358b276a7f460a685 265 SUPERFAMILY SSF55347 126 235 2.62E-33 T 14-10-2018 TSH58p_11235 d0d78dfa0ad8d07358b276a7f460a685 265 Gene3D G3DSA:3.30.360.10 126 233 2.8E-94 T 14-10-2018 TSH58p_11235 d0d78dfa0ad8d07358b276a7f460a685 265 Gene3D G3DSA:3.40.50.720 4 263 2.8E-94 T 14-10-2018 TSH58p_11235 d0d78dfa0ad8d07358b276a7f460a685 265 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 1 264 32.191 T 14-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSH58p_11235 d0d78dfa0ad8d07358b276a7f460a685 265 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 1 124 1.5E-33 T 14-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSH58p_21555 c3b42cc4d865a7a65783ad5262e421e0 270 Gene3D G3DSA:3.30.540.10 6 155 9.4E-38 T 14-10-2018 TSH58p_21555 c3b42cc4d865a7a65783ad5262e421e0 270 SUPERFAMILY SSF56655 17 268 1.7E-59 T 14-10-2018 TSH58p_21555 c3b42cc4d865a7a65783ad5262e421e0 270 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 93 106 - T 14-10-2018 IPR020583 Inositol monophosphatase, metal-binding site TSH58p_21555 c3b42cc4d865a7a65783ad5262e421e0 270 PRINTS PR00377 Inositol monophosphatase superfamily signature 93 109 3.5E-23 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_21555 c3b42cc4d865a7a65783ad5262e421e0 270 PRINTS PR00377 Inositol monophosphatase superfamily signature 216 240 3.5E-23 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_21555 c3b42cc4d865a7a65783ad5262e421e0 270 PRINTS PR00377 Inositol monophosphatase superfamily signature 142 165 3.5E-23 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_21555 c3b42cc4d865a7a65783ad5262e421e0 270 PRINTS PR00377 Inositol monophosphatase superfamily signature 66 82 3.5E-23 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_21555 c3b42cc4d865a7a65783ad5262e421e0 270 PRINTS PR00377 Inositol monophosphatase superfamily signature 44 64 3.5E-23 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_21555 c3b42cc4d865a7a65783ad5262e421e0 270 Gene3D G3DSA:3.40.190.80 173 268 3.0E-12 T 14-10-2018 TSH58p_21555 c3b42cc4d865a7a65783ad5262e421e0 270 Pfam PF00459 Inositol monophosphatase family 19 256 3.2E-45 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_31185 0b489fe2858564733f83874a2d402e25 252 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 222 242 1.5E-4 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSH58p_31185 0b489fe2858564733f83874a2d402e25 252 SUPERFAMILY SSF52540 4 242 5.11E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_31185 0b489fe2858564733f83874a2d402e25 252 Gene3D G3DSA:3.40.50.300 4 247 1.3E-67 T 14-10-2018 TSH58p_31185 0b489fe2858564733f83874a2d402e25 252 SMART SM00382 30 219 2.8E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_31185 0b489fe2858564733f83874a2d402e25 252 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_31185 0b489fe2858564733f83874a2d402e25 252 Pfam PF00005 ABC transporter 21 172 3.5E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_00630 5e6497787d65d178ed0e3e5a403f4608 142 SUPERFAMILY SSF52172 8 128 1.57E-34 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_00630 5e6497787d65d178ed0e3e5a403f4608 142 SMART SM00448 9 122 1.8E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_00630 5e6497787d65d178ed0e3e5a403f4608 142 Gene3D G3DSA:3.40.50.12740 8 140 1.3E-38 T 14-10-2018 TSH58p_00630 5e6497787d65d178ed0e3e5a403f4608 142 Pfam PF00072 Response regulator receiver domain 11 122 3.1E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_12515 b102d1df7acf044e133889e47ee79053 298 Gene3D G3DSA:3.40.50.150 33 265 1.5E-22 T 14-10-2018 TSH58p_12515 b102d1df7acf044e133889e47ee79053 298 Pfam PF13489 Methyltransferase domain 35 192 8.3E-13 T 14-10-2018 TSH58p_12515 b102d1df7acf044e133889e47ee79053 298 SUPERFAMILY SSF53335 35 220 2.17E-28 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_02810 22f68099e5cdef2bda2f129fa17d4553 423 Pfam PF00534 Glycosyl transferases group 1 238 386 6.0E-15 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 TSH58p_02810 22f68099e5cdef2bda2f129fa17d4553 423 SUPERFAMILY SSF53756 48 415 3.04E-45 T 14-10-2018 TSH58p_02810 22f68099e5cdef2bda2f129fa17d4553 423 Pfam PF13579 Glycosyl transferase 4-like domain 54 219 3.2E-10 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TSH58p_02810 22f68099e5cdef2bda2f129fa17d4553 423 Gene3D G3DSA:3.40.50.2000 235 401 7.1E-26 T 14-10-2018 TSH58p_02810 22f68099e5cdef2bda2f129fa17d4553 423 Gene3D G3DSA:3.40.50.2000 44 224 6.1E-8 T 14-10-2018 TSH58p_31980 4c7a8053c58593a3323d6eac6f85bee2 334 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 332 1.5E-125 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TSH58p_31980 4c7a8053c58593a3323d6eac6f85bee2 334 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 156 330 1.3E-50 T 14-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 TSH58p_31980 4c7a8053c58593a3323d6eac6f85bee2 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 6.2E-24 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSH58p_31980 4c7a8053c58593a3323d6eac6f85bee2 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 6.2E-24 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSH58p_31980 4c7a8053c58593a3323d6eac6f85bee2 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 267 276 6.2E-24 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSH58p_31980 4c7a8053c58593a3323d6eac6f85bee2 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 297 320 6.2E-24 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSH58p_31980 4c7a8053c58593a3323d6eac6f85bee2 334 Gene3D G3DSA:3.40.50.1370 5 329 6.0E-134 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TSH58p_31980 4c7a8053c58593a3323d6eac6f85bee2 334 Gene3D G3DSA:3.40.50.1370 151 319 6.0E-134 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TSH58p_31980 4c7a8053c58593a3323d6eac6f85bee2 334 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 333 79.794 T 14-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 TSH58p_31980 4c7a8053c58593a3323d6eac6f85bee2 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 2.0E-30 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TSH58p_31980 4c7a8053c58593a3323d6eac6f85bee2 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 229 239 2.0E-30 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TSH58p_31980 4c7a8053c58593a3323d6eac6f85bee2 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 311 322 2.0E-30 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TSH58p_31980 4c7a8053c58593a3323d6eac6f85bee2 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 2.0E-30 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TSH58p_31980 4c7a8053c58593a3323d6eac6f85bee2 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 2.0E-30 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TSH58p_31980 4c7a8053c58593a3323d6eac6f85bee2 334 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 4.4E-46 T 14-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 TSH58p_31980 4c7a8053c58593a3323d6eac6f85bee2 334 SUPERFAMILY SSF53671 4 333 1.23E-97 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TSH58p_31980 4c7a8053c58593a3323d6eac6f85bee2 334 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSH58p_10660 f3d58139ddee78257d348297f462e4b1 122 SUPERFAMILY SSF52980 14 120 1.29E-24 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TSH58p_10660 f3d58139ddee78257d348297f462e4b1 122 Pfam PF02021 Uncharacterised protein family UPF0102 18 107 7.9E-22 T 14-10-2018 IPR003509 Uncharacterised protein family UPF0102 TSH58p_10660 f3d58139ddee78257d348297f462e4b1 122 Gene3D G3DSA:3.40.1350.10 17 122 4.1E-32 T 14-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 TSH58p_10660 f3d58139ddee78257d348297f462e4b1 122 Hamap MF_00048 UPF0102 protein YraN [yraN]. 11 120 19.228 T 14-10-2018 IPR003509 Uncharacterised protein family UPF0102 TSH58p_09350 c2c22972cacdb107dbca5aac01f6bd28 164 SUPERFAMILY SSF55729 4 143 1.24E-28 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_09350 c2c22972cacdb107dbca5aac01f6bd28 164 Pfam PF13673 Acetyltransferase (GNAT) domain 49 128 4.9E-16 T 14-10-2018 IPR000182 GNAT domain TSH58p_09350 c2c22972cacdb107dbca5aac01f6bd28 164 Gene3D G3DSA:3.40.630.30 1 146 8.5E-43 T 14-10-2018 TSH58p_18580 54d047dfeefb3956a16d93af9f24dffe 467 SUPERFAMILY SSF51556 1 466 6.12E-163 T 14-10-2018 IPR032466 Metal-dependent hydrolase TSH58p_18580 54d047dfeefb3956a16d93af9f24dffe 467 Gene3D G3DSA:3.20.20.140 1 55 2.7E-17 T 14-10-2018 TSH58p_18580 54d047dfeefb3956a16d93af9f24dffe 467 Gene3D G3DSA:3.20.20.140 114 467 1.1E-119 T 14-10-2018 TSH58p_18580 54d047dfeefb3956a16d93af9f24dffe 467 Hamap MF_00675 Uronate isomerase [uxaC]. 1 467 39.701 T 14-10-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 TSH58p_18580 54d047dfeefb3956a16d93af9f24dffe 467 Pfam PF02614 Glucuronate isomerase 14 463 1.1E-78 T 14-10-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 TSH58p_28350 e0b9e26d66a4985787d1ffa1cd709a30 49 SUPERFAMILY SSF81469 17 48 1.22E-6 T 14-10-2018 IPR036596 Bacterial aa3 type cytochrome c oxidase subunit IV superfamily KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 TSH58p_28350 e0b9e26d66a4985787d1ffa1cd709a30 49 Gene3D G3DSA:1.20.5.160 1 48 2.1E-5 T 14-10-2018 IPR036596 Bacterial aa3 type cytochrome c oxidase subunit IV superfamily KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 TSH58p_28350 e0b9e26d66a4985787d1ffa1cd709a30 49 Pfam PF07835 Bacterial aa3 type cytochrome c oxidase subunit IV 18 48 1.1E-7 T 14-10-2018 IPR012422 Cytochrome c oxidase, subunit IV, bacterial aa3 type KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 TSH58p_27040 7a04f325e2fc0e3c7f70054f363fb426 223 SUPERFAMILY SSF52499 12 210 2.62E-46 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TSH58p_27040 7a04f325e2fc0e3c7f70054f363fb426 223 Gene3D G3DSA:3.40.50.850 13 206 7.4E-44 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TSH58p_27040 7a04f325e2fc0e3c7f70054f363fb426 223 Pfam PF00857 Isochorismatase family 20 170 1.4E-25 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 TSH58p_06570 566e2ff50a74c94c46b921f3988fe599 602 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 11 284 6.0E-80 T 14-10-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 TSH58p_06570 566e2ff50a74c94c46b921f3988fe599 602 Gene3D G3DSA:1.20.1530.20 3 383 3.8E-76 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily TSH58p_06570 566e2ff50a74c94c46b921f3988fe599 602 Pfam PF02254 TrkA-N domain 405 518 4.7E-21 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TSH58p_06570 566e2ff50a74c94c46b921f3988fe599 602 Pfam PF00999 Sodium/hydrogen exchanger family 7 375 1.8E-58 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TSH58p_06570 566e2ff50a74c94c46b921f3988fe599 602 SUPERFAMILY SSF51735 404 532 6.84E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_06570 566e2ff50a74c94c46b921f3988fe599 602 Gene3D G3DSA:3.40.50.720 403 564 9.3E-36 T 14-10-2018 TSH58p_01335 daa330b62772c4e3e81e105a83f30a99 287 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 276 3.5E-40 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_00190 c7d3b6955644f52e3ce06a87a9b0e33d 376 Pfam PF05343 M42 glutamyl aminopeptidase 52 340 1.2E-66 T 14-10-2018 IPR008007 Peptidase M42 TSH58p_00190 c7d3b6955644f52e3ce06a87a9b0e33d 376 PIRSF PIRSF001123 8 347 1.8E-28 T 14-10-2018 IPR008007 Peptidase M42 TSH58p_00190 c7d3b6955644f52e3ce06a87a9b0e33d 376 SUPERFAMILY SSF53187 11 347 2.51E-44 T 14-10-2018 TSH58p_00190 c7d3b6955644f52e3ce06a87a9b0e33d 376 SUPERFAMILY SSF101821 77 189 1.4E-24 T 14-10-2018 TSH58p_00190 c7d3b6955644f52e3ce06a87a9b0e33d 376 TIGRFAM TIGR03106 trio_M42_hydro: hydrolase, peptidase M42 family 7 348 3.4E-171 T 14-10-2018 IPR017537 Peptidase M42, hydrolase TSH58p_00190 c7d3b6955644f52e3ce06a87a9b0e33d 376 Gene3D G3DSA:3.40.630.10 18 344 5.4E-80 T 14-10-2018 TSH58p_00190 c7d3b6955644f52e3ce06a87a9b0e33d 376 Gene3D G3DSA:2.40.30.40 80 174 5.4E-80 T 14-10-2018 IPR023367 Peptidase M42, domain 2 TSH58p_05000 b46ab0f6c127f66b405467836e23916e 101 Pfam PF00699 Urease beta subunit 3 99 3.0E-46 T 14-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 TSH58p_05000 b46ab0f6c127f66b405467836e23916e 101 Hamap MF_01954 Urease subunit beta [ureB]. 1 101 32.07 T 14-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 TSH58p_05000 b46ab0f6c127f66b405467836e23916e 101 Gene3D G3DSA:2.10.150.10 1 101 1.3E-47 T 14-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 TSH58p_05000 b46ab0f6c127f66b405467836e23916e 101 SUPERFAMILY SSF51278 1 101 3.66E-48 T 14-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 TSH58p_05000 b46ab0f6c127f66b405467836e23916e 101 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 100 1.4E-45 T 14-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 TSH58p_27685 07a0833e89de2f87ea39503105132256 411 Pfam PF04143 Sulphur transport 62 390 8.1E-78 T 14-10-2018 IPR007272 Sulphur transport domain TSH58p_19330 4dd582ca91cdf554bdbfb9f2230f2745 200 SUPERFAMILY SSF81452 24 199 3.01E-41 T 14-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_19330 4dd582ca91cdf554bdbfb9f2230f2745 200 Pfam PF00510 Cytochrome c oxidase subunit III 79 198 1.0E-10 T 14-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_19330 4dd582ca91cdf554bdbfb9f2230f2745 200 Gene3D G3DSA:1.20.120.80 32 200 2.4E-43 T 14-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_28580 755056c01266637633cf386deb0bd9ac 279 SUPERFAMILY SSF161098 8 261 1.4E-43 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_28580 755056c01266637633cf386deb0bd9ac 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 260 1.0E-12 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_28580 755056c01266637633cf386deb0bd9ac 279 Gene3D G3DSA:1.10.3720.10 5 271 4.2E-38 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_24800 d371f83fb5f6e2a6ded1485317087066 65 Pfam PF07862 Nif11 domain 5 51 4.1E-7 T 14-10-2018 IPR012903 Nif11 domain TSH58p_21355 e414e37430d860956f6a19ad45250846 526 Gene3D G3DSA:3.40.309.10 268 456 1.7E-208 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TSH58p_21355 e414e37430d860956f6a19ad45250846 526 Gene3D G3DSA:3.40.605.10 43 521 1.7E-208 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TSH58p_21355 e414e37430d860956f6a19ad45250846 526 SUPERFAMILY SSF53720 18 520 3.14E-100 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSH58p_21355 e414e37430d860956f6a19ad45250846 526 Pfam PF00171 Aldehyde dehydrogenase family 19 459 2.0E-41 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TSH58p_04675 a8d2211a25141c91ee59519ad991f081 215 Pfam PF02493 MORN repeat 129 149 1.6 T 14-10-2018 IPR003409 MORN motif TSH58p_04675 a8d2211a25141c91ee59519ad991f081 215 Pfam PF02493 MORN repeat 106 128 1.0E-4 T 14-10-2018 IPR003409 MORN motif TSH58p_04675 a8d2211a25141c91ee59519ad991f081 215 SUPERFAMILY SSF82185 56 144 8.89E-13 T 14-10-2018 TSH58p_04675 a8d2211a25141c91ee59519ad991f081 215 Gene3D G3DSA:2.20.110.10 57 159 6.8E-11 T 14-10-2018 TSH58p_23890 0fd374eb5e0ab113d038367768c93cb6 134 Pfam PF04241 Protein of unknown function (DUF423) 22 109 1.5E-21 T 14-10-2018 IPR006696 Protein of unknown function DUF423 TSH58p_29075 4e01d4c597f63fb2ef2851fdf3e6e945 209 Pfam PF04972 BON domain 134 201 1.2E-18 T 14-10-2018 IPR007055 BON domain TSH58p_29075 4e01d4c597f63fb2ef2851fdf3e6e945 209 SMART SM00749 139 202 4.5E-5 T 14-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria TSH58p_07865 98894a552bf135624376f5fe17e0d94e 182 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 28 121 6.2E-12 T 14-10-2018 IPR000014 PAS domain TSH58p_07865 98894a552bf135624376f5fe17e0d94e 182 Pfam PF08447 PAS fold 40 122 4.0E-12 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 TSH58p_07865 98894a552bf135624376f5fe17e0d94e 182 SUPERFAMILY SSF55785 29 124 3.32E-25 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_07865 98894a552bf135624376f5fe17e0d94e 182 Gene3D G3DSA:3.30.450.20 28 126 1.3E-21 T 14-10-2018 TSH58p_08400 39308a17995089160db7b0656850ad29 319 Pfam PF01515 Phosphate acetyl/butaryl transferase 89 305 3.2E-49 T 14-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 TSH58p_08400 39308a17995089160db7b0656850ad29 319 PIRSF PIRSF000428 13 312 5.7E-92 T 14-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 TSH58p_08400 39308a17995089160db7b0656850ad29 319 SUPERFAMILY SSF53659 17 310 4.52E-71 T 14-10-2018 TSH58p_08400 39308a17995089160db7b0656850ad29 319 Gene3D G3DSA:3.40.718.10 13 309 1.7E-102 T 14-10-2018 TSH58p_18245 091337ae1827fb34eba69adaae54c8cc 136 SUPERFAMILY SSF53448 3 86 4.07E-7 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_18245 091337ae1827fb34eba69adaae54c8cc 136 Gene3D G3DSA:3.90.550.10 1 101 1.9E-8 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_20755 a5c7c65612474fd7bfc34a0ae53a2927 426 Pfam PF09375 Imelysin 41 398 3.2E-92 T 14-10-2018 IPR018976 Imelysin-like domain TSH58p_20755 a5c7c65612474fd7bfc34a0ae53a2927 426 Gene3D G3DSA:1.20.1420.20 17 402 3.8E-78 T 14-10-2018 IPR038352 Imelysin-like domain superfamily TSH58p_18825 232b49fd82d4be44edf95bfb3021c6a8 352 Pfam PF13508 Acetyltransferase (GNAT) domain 63 122 7.4E-7 T 14-10-2018 IPR000182 GNAT domain TSH58p_18825 232b49fd82d4be44edf95bfb3021c6a8 352 Gene3D G3DSA:3.40.630.30 9 341 7.4E-54 T 14-10-2018 TSH58p_18825 232b49fd82d4be44edf95bfb3021c6a8 352 SUPERFAMILY SSF55729 30 149 1.66E-13 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_18825 232b49fd82d4be44edf95bfb3021c6a8 352 SUPERFAMILY SSF55729 194 337 5.06E-13 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_31415 ae6db693956706bf357ad0cd0227b3db 474 SUPERFAMILY SSF51338 4 71 1.83E-13 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_31415 ae6db693956706bf357ad0cd0227b3db 474 SUPERFAMILY SSF51338 354 460 2.16E-37 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_31415 ae6db693956706bf357ad0cd0227b3db 474 Pfam PF01979 Amidohydrolase family 51 443 9.0E-28 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TSH58p_31415 ae6db693956706bf357ad0cd0227b3db 474 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 7 461 8.7E-167 T 14-10-2018 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 TSH58p_31415 ae6db693956706bf357ad0cd0227b3db 474 SUPERFAMILY SSF51556 55 389 1.32E-104 T 14-10-2018 IPR032466 Metal-dependent hydrolase TSH58p_31415 ae6db693956706bf357ad0cd0227b3db 474 Gene3D G3DSA:3.20.20.140 55 430 4.7E-179 T 14-10-2018 TSH58p_31415 ae6db693956706bf357ad0cd0227b3db 474 Gene3D G3DSA:2.30.40.10 5 459 4.7E-179 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_13855 d82e755a35f523c19e58025500d1f4d2 274 PIRSF PIRSF006648 3 264 3.0E-36 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSH58p_13855 d82e755a35f523c19e58025500d1f4d2 274 TIGRFAM TIGR03861 phenyl_ABC_PedC: alcohol ABC transporter, permease protein 15 264 1.5E-129 T 14-10-2018 IPR022403 Alcohol ABC transporter, permease protein TSH58p_13855 d82e755a35f523c19e58025500d1f4d2 274 PRINTS PR00164 ABC-2 type transport system membrane protein signature 151 175 4.0E-8 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSH58p_13855 d82e755a35f523c19e58025500d1f4d2 274 PRINTS PR00164 ABC-2 type transport system membrane protein signature 34 55 4.0E-8 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSH58p_13855 d82e755a35f523c19e58025500d1f4d2 274 PRINTS PR00164 ABC-2 type transport system membrane protein signature 188 207 4.0E-8 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSH58p_13855 d82e755a35f523c19e58025500d1f4d2 274 Pfam PF01061 ABC-2 type transporter 18 234 8.9E-31 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TSH58p_06875 93b16d50e81816b0c32faf98d84ab50d 197 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 5 188 37.22 T 14-10-2018 IPR004507 Flavin prenyltransferase UbiX-like TSH58p_06875 93b16d50e81816b0c32faf98d84ab50d 197 Gene3D G3DSA:3.40.50.1950 5 195 1.4E-77 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TSH58p_06875 93b16d50e81816b0c32faf98d84ab50d 197 SUPERFAMILY SSF52507 6 188 8.76E-62 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TSH58p_06875 93b16d50e81816b0c32faf98d84ab50d 197 Pfam PF02441 Flavoprotein 6 167 1.9E-24 T 14-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 TSH58p_06875 93b16d50e81816b0c32faf98d84ab50d 197 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 6 186 1.1E-72 T 14-10-2018 IPR004507 Flavin prenyltransferase UbiX-like TSH58p_27030 23e0154e3bbd07317f72c22d23475531 218 SMART SM00448 17 128 4.8E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_27030 23e0154e3bbd07317f72c22d23475531 218 SUPERFAMILY SSF46894 143 212 1.97E-20 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_27030 23e0154e3bbd07317f72c22d23475531 218 SUPERFAMILY SSF52172 19 166 1.2E-30 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_27030 23e0154e3bbd07317f72c22d23475531 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_27030 23e0154e3bbd07317f72c22d23475531 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.6E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_27030 23e0154e3bbd07317f72c22d23475531 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.6E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_27030 23e0154e3bbd07317f72c22d23475531 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.6E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_27030 23e0154e3bbd07317f72c22d23475531 218 Pfam PF00072 Response regulator receiver domain 19 128 6.0E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_27030 23e0154e3bbd07317f72c22d23475531 218 Gene3D G3DSA:1.10.10.10 146 210 2.3E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_27030 23e0154e3bbd07317f72c22d23475531 218 SMART SM00421 152 209 4.8E-26 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_27030 23e0154e3bbd07317f72c22d23475531 218 Gene3D G3DSA:3.40.50.2300 12 143 4.4E-46 T 14-10-2018 TSH58p_27030 23e0154e3bbd07317f72c22d23475531 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 2.3E-24 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_29155 0ff0dc6ffe89266e959676fc03f35582 360 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 251 338 2.6E-26 T 14-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TSH58p_29155 0ff0dc6ffe89266e959676fc03f35582 360 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 113 190 1.0E-15 T 14-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TSH58p_29155 0ff0dc6ffe89266e959676fc03f35582 360 SUPERFAMILY SSF53901 9 339 1.14E-48 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_29155 0ff0dc6ffe89266e959676fc03f35582 360 Gene3D G3DSA:3.40.47.10 1 350 1.2E-112 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_12675 fe9fdba6b1d7c8c68dc981a566d47ddd 373 SUPERFAMILY SSF53448 11 273 3.7E-39 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_12675 fe9fdba6b1d7c8c68dc981a566d47ddd 373 Pfam PF00535 Glycosyl transferase family 2 12 174 3.5E-34 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_12675 fe9fdba6b1d7c8c68dc981a566d47ddd 373 Gene3D G3DSA:3.90.550.10 2 214 8.0E-38 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_18315 058163ee9629da5a49655b9d62ba87fd 361 Pfam PF13692 Glycosyl transferases group 1 212 316 7.5E-14 T 14-10-2018 TSH58p_18315 058163ee9629da5a49655b9d62ba87fd 361 Gene3D G3DSA:3.40.50.2000 205 335 9.0E-24 T 14-10-2018 TSH58p_18315 058163ee9629da5a49655b9d62ba87fd 361 SUPERFAMILY SSF53756 2 349 1.88E-31 T 14-10-2018 TSH58p_19530 a82f229f803d5ad136a3a43f7d95bf2a 348 SUPERFAMILY SSF144052 140 341 5.75E-16 T 14-10-2018 TSH58p_32155 e495ab4a9983fa1bd573b00f1989f983 287 SUPERFAMILY SSF161098 88 267 2.49E-30 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_32155 e495ab4a9983fa1bd573b00f1989f983 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 278 5.9E-27 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_32155 e495ab4a9983fa1bd573b00f1989f983 287 Gene3D G3DSA:1.10.3720.10 88 278 3.1E-24 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_24370 684595082c9f1ddab2c99d870779c7c0 144 Pfam PF00072 Response regulator receiver domain 20 136 7.0E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_24370 684595082c9f1ddab2c99d870779c7c0 144 SMART SM00448 18 136 7.4E-35 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_24370 684595082c9f1ddab2c99d870779c7c0 144 SUPERFAMILY SSF52172 17 141 6.83E-36 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_24370 684595082c9f1ddab2c99d870779c7c0 144 Gene3D G3DSA:3.40.50.2300 12 142 1.2E-33 T 14-10-2018 TSH58p_23105 032338845c10b1ae2cb5d619eecb72bd 231 SMART SM00862 153 227 1.2E-19 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_23105 032338845c10b1ae2cb5d619eecb72bd 231 SUPERFAMILY SSF46894 130 227 1.73E-22 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_23105 032338845c10b1ae2cb5d619eecb72bd 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 227 2.2E-19 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_23105 032338845c10b1ae2cb5d619eecb72bd 231 SMART SM00448 2 112 8.3E-47 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_23105 032338845c10b1ae2cb5d619eecb72bd 231 Gene3D G3DSA:3.40.50.2300 1 123 3.3E-39 T 14-10-2018 TSH58p_23105 032338845c10b1ae2cb5d619eecb72bd 231 Gene3D G3DSA:1.10.10.10 132 229 4.2E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_23105 032338845c10b1ae2cb5d619eecb72bd 231 SUPERFAMILY SSF52172 1 122 3.42E-44 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_23105 032338845c10b1ae2cb5d619eecb72bd 231 Pfam PF00072 Response regulator receiver domain 4 113 3.5E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_18415 db1c4cab8e4c88199c597d34d3c38c6d 260 PRINTS PR01868 ABC transporter family E signature 63 88 1.6E-8 T 14-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 TSH58p_18415 db1c4cab8e4c88199c597d34d3c38c6d 260 PRINTS PR01868 ABC transporter family E signature 36 56 1.6E-8 T 14-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 TSH58p_18415 db1c4cab8e4c88199c597d34d3c38c6d 260 Gene3D G3DSA:3.40.50.300 35 253 1.9E-39 T 14-10-2018 TSH58p_18415 db1c4cab8e4c88199c597d34d3c38c6d 260 Pfam PF00005 ABC transporter 49 181 2.2E-19 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_18415 db1c4cab8e4c88199c597d34d3c38c6d 260 SMART SM00382 58 247 4.4E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_18415 db1c4cab8e4c88199c597d34d3c38c6d 260 SUPERFAMILY SSF52540 46 244 3.35E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_16475 94e205701611607424863b446c031d70 203 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 166 179 - T 14-10-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 TSH58p_16475 94e205701611607424863b446c031d70 203 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 6 201 9.4E-74 T 14-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 TSH58p_16475 94e205701611607424863b446c031d70 203 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 156 203 1.0E-15 T 14-10-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 TSH58p_16475 94e205701611607424863b446c031d70 203 PIRSF PIRSF000190 1 203 1.7E-75 T 14-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 TSH58p_16475 94e205701611607424863b446c031d70 203 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 17 103 4.9E-27 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 TSH58p_16475 94e205701611607424863b446c031d70 203 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 2 203 39.177 T 14-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 TSH58p_16475 94e205701611607424863b446c031d70 203 SUPERFAMILY SSF50475 7 203 2.14E-65 T 14-10-2018 TSH58p_16475 94e205701611607424863b446c031d70 203 Gene3D G3DSA:2.30.110.10 1 203 7.0E-80 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TSH58p_22350 83bd98c72b5dda01531c1ded2cc57b60 422 SUPERFAMILY SSF56349 219 395 1.06E-16 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TSH58p_22350 83bd98c72b5dda01531c1ded2cc57b60 422 Pfam PF00589 Phage integrase family 223 360 3.5E-12 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TSH58p_22350 83bd98c72b5dda01531c1ded2cc57b60 422 Gene3D G3DSA:1.10.443.10 217 406 1.1E-20 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TSH58p_14360 38a736869ed643467a8f2e2697bc6113 231 ProDom PD201674 DIVISION CELL RP568 MEMBRANE TRANSMEMBRANE FTSL 20 83 0.006 T 14-10-2018 TSH58p_08245 a1821ba3daf4d61d55fb6fba62db4132 536 Gene3D G3DSA:3.30.300.30 427 534 3.3E-21 T 14-10-2018 TSH58p_08245 a1821ba3daf4d61d55fb6fba62db4132 536 Pfam PF13193 AMP-binding enzyme C-terminal domain 441 510 4.2E-9 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSH58p_08245 a1821ba3daf4d61d55fb6fba62db4132 536 Gene3D G3DSA:3.40.50.12780 3 426 3.4E-78 T 14-10-2018 TSH58p_08245 a1821ba3daf4d61d55fb6fba62db4132 536 ProSitePatterns PS00455 Putative AMP-binding domain signature. 183 194 - T 14-10-2018 IPR020845 AMP-binding, conserved site TSH58p_08245 a1821ba3daf4d61d55fb6fba62db4132 536 Pfam PF00501 AMP-binding enzyme 15 432 8.2E-61 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_08245 a1821ba3daf4d61d55fb6fba62db4132 536 SUPERFAMILY SSF56801 10 528 3.66E-103 T 14-10-2018 TSH58p_19435 66b97154b12acc2b9be221eba3a5d355 234 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_19435 66b97154b12acc2b9be221eba3a5d355 234 PIRSF PIRSF039137 1 234 1.4E-104 T 14-10-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 TSH58p_19435 66b97154b12acc2b9be221eba3a5d355 234 Pfam PF00005 ABC transporter 17 162 4.4E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_19435 66b97154b12acc2b9be221eba3a5d355 234 SUPERFAMILY SSF52540 2 232 4.99E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_19435 66b97154b12acc2b9be221eba3a5d355 234 SMART SM00382 26 217 1.8E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_19435 66b97154b12acc2b9be221eba3a5d355 234 Gene3D G3DSA:3.40.50.300 1 234 6.2E-69 T 14-10-2018 TSH58p_08360 265bb92c4ebaf66f0327fec81736a1aa 340 Gene3D G3DSA:3.40.190.10 29 326 1.1E-55 T 14-10-2018 TSH58p_08360 265bb92c4ebaf66f0327fec81736a1aa 340 SUPERFAMILY SSF53850 27 258 3.18E-27 T 14-10-2018 TSH58p_08360 265bb92c4ebaf66f0327fec81736a1aa 340 Pfam PF09084 NMT1/THI5 like 38 245 3.5E-31 T 14-10-2018 IPR015168 SsuA/THI5-like TSH58p_08360 265bb92c4ebaf66f0327fec81736a1aa 340 Gene3D G3DSA:3.40.190.10 108 213 1.1E-55 T 14-10-2018 TSH58p_29840 f76aff343874365ad5cf121a76948309 180 Pfam PF00857 Isochorismatase family 8 157 5.2E-32 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 TSH58p_29840 f76aff343874365ad5cf121a76948309 180 Gene3D G3DSA:3.40.50.850 2 180 4.4E-55 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TSH58p_29840 f76aff343874365ad5cf121a76948309 180 SUPERFAMILY SSF52499 1 180 2.49E-48 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TSH58p_21600 353d869e98a3e9a9650c930ef2c60fbc 677 Pfam PF00361 Proton-conducting membrane transporter 132 419 5.7E-53 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_21600 353d869e98a3e9a9650c930ef2c60fbc 677 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 311 323 7.4E-7 T 14-10-2018 TSH58p_21600 353d869e98a3e9a9650c930ef2c60fbc 677 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 75 100 7.4E-7 T 14-10-2018 TSH58p_21600 353d869e98a3e9a9650c930ef2c60fbc 677 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 219 240 7.4E-7 T 14-10-2018 TSH58p_21600 353d869e98a3e9a9650c930ef2c60fbc 677 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 436 455 7.4E-7 T 14-10-2018 TSH58p_24690 e6bf99489b512ca472f6460b0291a880 321 ProSitePatterns PS01053 Arginase family signature. 232 253 - T 14-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 TSH58p_24690 e6bf99489b512ca472f6460b0291a880 321 Gene3D G3DSA:3.40.800.10 7 311 2.7E-89 T 14-10-2018 TSH58p_24690 e6bf99489b512ca472f6460b0291a880 321 PIRSF PIRSF036979 2 303 9.2E-31 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 TSH58p_24690 e6bf99489b512ca472f6460b0291a880 321 SUPERFAMILY SSF52768 13 305 1.39E-82 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily TSH58p_24690 e6bf99489b512ca472f6460b0291a880 321 Pfam PF00491 Arginase family 13 302 5.6E-71 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 TSH58p_24690 e6bf99489b512ca472f6460b0291a880 321 PRINTS PR00116 Arginase signature 99 114 3.3E-48 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 TSH58p_24690 e6bf99489b512ca472f6460b0291a880 321 PRINTS PR00116 Arginase signature 264 278 3.3E-48 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 TSH58p_24690 e6bf99489b512ca472f6460b0291a880 321 PRINTS PR00116 Arginase signature 126 153 3.3E-48 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 TSH58p_24690 e6bf99489b512ca472f6460b0291a880 321 PRINTS PR00116 Arginase signature 229 258 3.3E-48 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 TSH58p_24690 e6bf99489b512ca472f6460b0291a880 321 PRINTS PR00116 Arginase signature 180 198 3.3E-48 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 TSH58p_24690 e6bf99489b512ca472f6460b0291a880 321 TIGRFAM TIGR01229 rocF_arginase: arginase 14 305 7.4E-86 T 14-10-2018 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: R-HSA-70635 TSH58p_01000 938cf16c7f13797c6f588019f61f1603 577 Gene3D G3DSA:1.10.3720.10 6 284 5.5E-51 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_01000 938cf16c7f13797c6f588019f61f1603 577 Gene3D G3DSA:1.10.3720.10 298 557 1.1E-41 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_01000 938cf16c7f13797c6f588019f61f1603 577 SUPERFAMILY SSF161098 307 546 1.59E-40 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_01000 938cf16c7f13797c6f588019f61f1603 577 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 380 547 6.8E-8 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_01000 938cf16c7f13797c6f588019f61f1603 577 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 272 7.3E-11 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_01000 938cf16c7f13797c6f588019f61f1603 577 SUPERFAMILY SSF161098 8 278 5.79E-48 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_30360 b64d555a7462282abfc776addfeb8ea1 750 SMART SM00900 85 174 3.9E-11 T 14-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 TSH58p_30360 b64d555a7462282abfc776addfeb8ea1 750 SUPERFAMILY SSF54862 526 692 1.74E-11 T 14-10-2018 TSH58p_30360 b64d555a7462282abfc776addfeb8ea1 750 Pfam PF04205 FMN-binding domain 85 163 1.4E-6 T 14-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 TSH58p_30360 b64d555a7462282abfc776addfeb8ea1 750 Pfam PF12801 4Fe-4S binding domain 508 554 4.8E-14 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_30360 b64d555a7462282abfc776addfeb8ea1 750 Pfam PF12801 4Fe-4S binding domain 610 654 5.1E-6 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_30360 b64d555a7462282abfc776addfeb8ea1 750 PIRSF PIRSF036354 1 738 0.0 T 14-10-2018 IPR011399 Nitrous oxide reductase expression regulator NosR GO:0003677|GO:0016020|GO:0045893 TSH58p_19385 cc102265bfe9fdcfd62211a6eb1c5b3f 478 SUPERFAMILY SSF56176 12 225 4.03E-73 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TSH58p_19385 cc102265bfe9fdcfd62211a6eb1c5b3f 478 Pfam PF01565 FAD binding domain 49 185 6.1E-35 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TSH58p_19385 cc102265bfe9fdcfd62211a6eb1c5b3f 478 Gene3D G3DSA:3.30.465.10 103 223 6.4E-45 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TSH58p_19385 cc102265bfe9fdcfd62211a6eb1c5b3f 478 Pfam PF02913 FAD linked oxidases, C-terminal domain 225 475 1.4E-57 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 TSH58p_19385 cc102265bfe9fdcfd62211a6eb1c5b3f 478 Gene3D G3DSA:3.30.43.10 5 101 1.7E-22 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 TSH58p_19385 cc102265bfe9fdcfd62211a6eb1c5b3f 478 Gene3D G3DSA:3.30.70.2740 349 435 7.9E-30 T 14-10-2018 TSH58p_19385 cc102265bfe9fdcfd62211a6eb1c5b3f 478 SUPERFAMILY SSF55103 200 475 1.42E-58 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 TSH58p_19385 cc102265bfe9fdcfd62211a6eb1c5b3f 478 Gene3D G3DSA:3.30.70.2190 225 348 5.9E-36 T 14-10-2018 TSH58p_19385 cc102265bfe9fdcfd62211a6eb1c5b3f 478 Gene3D G3DSA:1.10.45.10 436 476 4.8E-15 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 TSH58p_30985 4712df989424a6308e0c431b0e7f1bbb 257 Pfam PF00005 ABC transporter 27 160 6.8E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_30985 4712df989424a6308e0c431b0e7f1bbb 257 SUPERFAMILY SSF52540 14 211 7.28E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_30985 4712df989424a6308e0c431b0e7f1bbb 257 SMART SM00382 36 210 8.2E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_30985 4712df989424a6308e0c431b0e7f1bbb 257 Gene3D G3DSA:3.40.50.300 13 218 2.3E-57 T 14-10-2018 TSH58p_30985 4712df989424a6308e0c431b0e7f1bbb 257 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_10115 b305d6790dccef1ca6eec5ee37f1fb58 219 SUPERFAMILY SSF55729 1 130 7.75E-16 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_10115 b305d6790dccef1ca6eec5ee37f1fb58 219 Gene3D G3DSA:3.40.630.30 1 172 6.1E-31 T 14-10-2018 TSH58p_10115 b305d6790dccef1ca6eec5ee37f1fb58 219 Pfam PF00583 Acetyltransferase (GNAT) family 24 127 4.2E-5 T 14-10-2018 IPR000182 GNAT domain TSH58p_01910 32a9d0799f0601b3198e8e9b5812928e 342 Pfam PF05145 Transition state regulatory protein AbrB 31 335 5.5E-71 T 14-10-2018 IPR007820 AbrB family GO:0010468|GO:0016021 TSH58p_01910 32a9d0799f0601b3198e8e9b5812928e 342 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 185 332 2.2E-31 T 14-10-2018 IPR017516 AbrB duplication TSH58p_01910 32a9d0799f0601b3198e8e9b5812928e 342 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 9 162 4.6E-30 T 14-10-2018 IPR017516 AbrB duplication TSH58p_01910 32a9d0799f0601b3198e8e9b5812928e 342 PIRSF PIRSF038991 1 338 8.4E-70 T 14-10-2018 IPR007820 AbrB family GO:0010468|GO:0016021 TSH58p_17070 885883ba90cfa0e7f1216da32863be0c 208 PIRSF PIRSF015617 11 208 3.0E-71 T 14-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 TSH58p_17070 885883ba90cfa0e7f1216da32863be0c 208 SUPERFAMILY SSF52540 18 208 2.38E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_17070 885883ba90cfa0e7f1216da32863be0c 208 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 36 208 2.7E-70 T 14-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 TSH58p_17070 885883ba90cfa0e7f1216da32863be0c 208 Gene3D G3DSA:3.40.50.300 16 208 1.0E-70 T 14-10-2018 TSH58p_17070 885883ba90cfa0e7f1216da32863be0c 208 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 37 208 4.8E-64 T 14-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 TSH58p_11025 7b4ee8dc6bad55d7b501fa7c1c3044d1 119 SUPERFAMILY SSF52833 8 108 8.16E-27 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_11025 7b4ee8dc6bad55d7b501fa7c1c3044d1 119 Gene3D G3DSA:3.40.30.10 9 112 1.8E-30 T 14-10-2018 TSH58p_16640 9b4ada14dd82f21110bcc447ebcfbda0 544 Pfam PF13193 AMP-binding enzyme C-terminal domain 455 531 6.9E-22 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSH58p_16640 9b4ada14dd82f21110bcc447ebcfbda0 544 ProSitePatterns PS00455 Putative AMP-binding domain signature. 188 199 - T 14-10-2018 IPR020845 AMP-binding, conserved site TSH58p_16640 9b4ada14dd82f21110bcc447ebcfbda0 544 SUPERFAMILY SSF56801 11 543 1.31E-139 T 14-10-2018 TSH58p_16640 9b4ada14dd82f21110bcc447ebcfbda0 544 Pfam PF00501 AMP-binding enzyme 27 446 7.2E-90 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_16640 9b4ada14dd82f21110bcc447ebcfbda0 544 Gene3D G3DSA:3.40.50.12780 7 441 1.4E-109 T 14-10-2018 TSH58p_16640 9b4ada14dd82f21110bcc447ebcfbda0 544 Gene3D G3DSA:3.30.300.310 442 543 7.8E-34 T 14-10-2018 TSH58p_15300 2a279ae932d851f2717bf12662dbac09 265 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 1.3E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_15300 2a279ae932d851f2717bf12662dbac09 265 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 106 1.3E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_15300 2a279ae932d851f2717bf12662dbac09 265 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 1.3E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_15300 2a279ae932d851f2717bf12662dbac09 265 PRINTS PR00111 Alpha/beta hydrolase fold signature 208 222 1.3E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_15300 2a279ae932d851f2717bf12662dbac09 265 SUPERFAMILY SSF53474 4 257 5.08E-47 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_15300 2a279ae932d851f2717bf12662dbac09 265 Gene3D G3DSA:3.40.50.1820 3 264 3.3E-49 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_15300 2a279ae932d851f2717bf12662dbac09 265 Pfam PF00561 alpha/beta hydrolase fold 24 155 1.3E-19 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_14700 9d1606d10aa85c9c120a73a359c0176e 451 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 254 415 4.5E-29 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_14700 9d1606d10aa85c9c120a73a359c0176e 451 Pfam PF11563 Protoglobin 12 167 2.0E-12 T 14-10-2018 TSH58p_14700 9d1606d10aa85c9c120a73a359c0176e 451 SUPERFAMILY SSF46458 10 159 1.73E-7 T 14-10-2018 IPR009050 Globin-like superfamily TSH58p_14700 9d1606d10aa85c9c120a73a359c0176e 451 Gene3D G3DSA:1.10.287.950 167 445 2.5E-52 T 14-10-2018 TSH58p_14700 9d1606d10aa85c9c120a73a359c0176e 451 SUPERFAMILY SSF58104 163 444 6.67E-59 T 14-10-2018 TSH58p_14700 9d1606d10aa85c9c120a73a359c0176e 451 SMART SM00283 191 445 7.1E-52 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_14700 9d1606d10aa85c9c120a73a359c0176e 451 Gene3D G3DSA:1.10.490.10 10 166 6.4E-15 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 TSH58p_29500 f26699ddc5d67d77160ea2724d53c24d 235 Pfam PF04273 Putative phosphatase (DUF442) 51 144 2.7E-8 T 14-10-2018 IPR005939 Beta-lactamase hydrolase-like GO:0016787 TSH58p_29500 f26699ddc5d67d77160ea2724d53c24d 235 Gene3D G3DSA:3.90.190.10 45 187 4.5E-30 T 14-10-2018 IPR029021 Protein-tyrosine phosphatase-like TSH58p_29500 f26699ddc5d67d77160ea2724d53c24d 235 SUPERFAMILY SSF52799 46 190 1.36E-24 T 14-10-2018 IPR029021 Protein-tyrosine phosphatase-like TSH58p_22980 f0e097db0425534cf30462af9465b0cd 384 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 33 350 4.5E-134 T 14-10-2018 IPR017778 ABC transporter, urea, permease protein, UrtC TSH58p_22980 f0e097db0425534cf30462af9465b0cd 384 Pfam PF02653 Branched-chain amino acid transport system / permease component 40 340 5.6E-36 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_12350 8bc764e0bfd4401138ab22f38046e719 238 Pfam PF00149 Calcineurin-like phosphoesterase 6 205 1.6E-16 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TSH58p_12350 8bc764e0bfd4401138ab22f38046e719 238 SUPERFAMILY SSF56300 6 237 8.39E-35 T 14-10-2018 TSH58p_12350 8bc764e0bfd4401138ab22f38046e719 238 PIRSF PIRSF008292 4 238 5.9E-86 T 14-10-2018 IPR016538 Uncharacterised conserved protein UCP008292 TSH58p_12350 8bc764e0bfd4401138ab22f38046e719 238 Gene3D G3DSA:3.60.21.10 1 236 2.6E-20 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like TSH58p_04070 16678fb48e66ab5e14e779baa64f7fe0 333 Gene3D G3DSA:1.10.8.1150 37 107 5.3E-12 T 14-10-2018 TSH58p_04070 16678fb48e66ab5e14e779baa64f7fe0 333 Pfam PF02618 YceG-like family 41 313 6.4E-83 T 14-10-2018 IPR003770 Endolytic murein transglycosylase TSH58p_04070 16678fb48e66ab5e14e779baa64f7fe0 333 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 140 315 9.3E-65 T 14-10-2018 IPR003770 Endolytic murein transglycosylase TSH58p_04070 16678fb48e66ab5e14e779baa64f7fe0 333 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 7 320 33.995 T 14-10-2018 IPR003770 Endolytic murein transglycosylase TSH58p_04070 16678fb48e66ab5e14e779baa64f7fe0 333 Gene3D G3DSA:3.30.160.60 286 323 9.3E-17 T 14-10-2018 TSH58p_31055 cae1f40fe17a56a418a0f8f90c846334 704 Pfam PF04632 Fusaric acid resistance protein family 38 696 2.8E-178 T 14-10-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0022857|GO:0055085 TSH58p_16340 69da25f284e725f288754b4878432c9e 317 Gene3D G3DSA:3.40.50.720 1 316 3.8E-71 T 14-10-2018 TSH58p_16340 69da25f284e725f288754b4878432c9e 317 SUPERFAMILY SSF51735 1 314 7.42E-73 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_16340 69da25f284e725f288754b4878432c9e 317 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 223 1.8E-35 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TSH58p_05275 5293f694de21bbdbdcb44529e2b0d904 599 Pfam PF07167 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus 108 280 2.2E-82 T 14-10-2018 IPR010941 Poly-beta-hydroxybutyrate polymerase, N-terminal domain GO:0042619 TSH58p_05275 5293f694de21bbdbdcb44529e2b0d904 599 SUPERFAMILY SSF53474 238 532 3.04E-44 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_05275 5293f694de21bbdbdcb44529e2b0d904 599 TIGRFAM TIGR01838 PHA_synth_I: poly(R)-hydroxyalkanoic acid synthase, class I 65 595 8.3E-246 T 14-10-2018 IPR010963 Poly(R)-hydroxyalkanoic acid synthase, class I GO:0005737|GO:0016746|GO:0042619 TSH58p_05275 5293f694de21bbdbdcb44529e2b0d904 599 Pfam PF00561 alpha/beta hydrolase fold 291 523 8.7E-13 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_28665 785cbfec274f182d74153e8d6e38775d 183 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 20 173 1.2E-56 T 14-10-2018 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 TSH58p_28665 785cbfec274f182d74153e8d6e38775d 183 SUPERFAMILY SSF52540 20 179 4.11E-24 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_28665 785cbfec274f182d74153e8d6e38775d 183 Pfam PF01202 Shikimate kinase 27 135 6.2E-12 T 14-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 TSH58p_28665 785cbfec274f182d74153e8d6e38775d 183 Gene3D G3DSA:3.40.50.300 17 182 1.3E-61 T 14-10-2018 TSH58p_27980 ad9509ec059f7570e0806ca0bbf6e8ac 224 Hamap MF_00052_B Ribonuclease HII [rnhB]. 32 216 34.543 T 14-10-2018 IPR022898 Ribonuclease HII GO:0004523 TSH58p_27980 ad9509ec059f7570e0806ca0bbf6e8ac 224 Gene3D G3DSA:3.30.420.10 19 223 1.1E-69 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TSH58p_27980 ad9509ec059f7570e0806ca0bbf6e8ac 224 SUPERFAMILY SSF53098 28 221 7.89E-61 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily TSH58p_27980 ad9509ec059f7570e0806ca0bbf6e8ac 224 Pfam PF01351 Ribonuclease HII 34 215 2.0E-40 T 14-10-2018 IPR024567 Ribonuclease HII/HIII domain TSH58p_03870 509eda85b63ecdeb054c076f5c2483c3 187 SUPERFAMILY SSF51182 3 178 3.87E-36 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_03870 509eda85b63ecdeb054c076f5c2483c3 187 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 1 172 34.313 T 14-10-2018 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.54+1.13.11.53|MetaCyc: PWY-4361|MetaCyc: PWY-5389 TSH58p_03870 509eda85b63ecdeb054c076f5c2483c3 187 Gene3D G3DSA:2.60.120.10 2 157 4.7E-46 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_03870 509eda85b63ecdeb054c076f5c2483c3 187 Pfam PF03079 ARD/ARD' family 66 165 3.4E-27 T 14-10-2018 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 TSH58p_30745 ac314f867aabf2ecd29e7868b7ae8834 535 Gene3D G3DSA:3.40.190.10 15 289 1.4E-64 T 14-10-2018 TSH58p_30745 ac314f867aabf2ecd29e7868b7ae8834 535 PIRSF PIRSF002741 1 529 4.2E-87 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TSH58p_30745 ac314f867aabf2ecd29e7868b7ae8834 535 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 80 433 5.1E-76 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain TSH58p_30745 ac314f867aabf2ecd29e7868b7ae8834 535 SUPERFAMILY SSF53850 38 524 5.07E-117 T 14-10-2018 TSH58p_30745 ac314f867aabf2ecd29e7868b7ae8834 535 Gene3D G3DSA:3.10.105.10 297 507 9.2E-45 T 14-10-2018 TSH58p_13375 e8154480ccee7bebb3d6ccb1df2244f9 273 Gene3D G3DSA:3.40.50.300 62 174 4.1E-24 T 14-10-2018 TSH58p_13375 e8154480ccee7bebb3d6ccb1df2244f9 273 SUPERFAMILY SSF52540 61 174 5.67E-26 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_13375 e8154480ccee7bebb3d6ccb1df2244f9 273 PIRSF PIRSF034285 13 267 4.3E-67 T 14-10-2018 IPR017026 Inducible mutagenesis protein A TSH58p_21075 da5077f8cc057bd7e36bb664580c24c5 247 Gene3D G3DSA:1.10.3810.10 77 230 1.4E-20 T 14-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_21075 da5077f8cc057bd7e36bb664580c24c5 247 Pfam PF00912 Transglycosylase 85 221 1.3E-19 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_21075 da5077f8cc057bd7e36bb664580c24c5 247 SUPERFAMILY SSF53955 74 224 1.1E-24 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily TSH58p_09095 0bcadaee98fac237302907a93121f5b5 250 SMART SM00382 35 228 2.2E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_09095 0bcadaee98fac237302907a93121f5b5 250 Gene3D G3DSA:3.40.50.300 6 231 3.7E-63 T 14-10-2018 TSH58p_09095 0bcadaee98fac237302907a93121f5b5 250 SUPERFAMILY SSF52540 9 240 8.96E-69 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_09095 0bcadaee98fac237302907a93121f5b5 250 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_09095 0bcadaee98fac237302907a93121f5b5 250 Pfam PF00005 ABC transporter 26 165 5.5E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_02480 7bf65f5bc48a58e74d9f549fac8b565f 244 Gene3D G3DSA:1.10.1740.10 15 116 6.7E-11 T 14-10-2018 TSH58p_02480 7bf65f5bc48a58e74d9f549fac8b565f 244 SUPERFAMILY SSF88946 15 119 3.57E-15 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_02480 7bf65f5bc48a58e74d9f549fac8b565f 244 Gene3D G3DSA:1.10.10.10 117 204 6.7E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_02480 7bf65f5bc48a58e74d9f549fac8b565f 244 SUPERFAMILY SSF88659 123 202 7.48E-9 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSH58p_02480 7bf65f5bc48a58e74d9f549fac8b565f 244 Pfam PF04542 Sigma-70 region 2 41 107 8.9E-7 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_02480 7bf65f5bc48a58e74d9f549fac8b565f 244 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 38 200 3.0E-16 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TSH58p_24005 6a42469fb4cc6f9a9c7f6bf074d82568 343 Pfam PF02653 Branched-chain amino acid transport system / permease component 65 323 2.1E-37 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_07935 b2c1798d76c5d2ab1adc5475c5e3a22f 266 SUPERFAMILY SSF53213 14 262 2.09E-83 T 14-10-2018 TSH58p_07935 b2c1798d76c5d2ab1adc5475c5e3a22f 266 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 17 262 4.7E-44 T 14-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 TSH58p_07935 b2c1798d76c5d2ab1adc5475c5e3a22f 266 PIRSF PIRSF006157 11 264 3.1E-85 T 14-10-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 TSH58p_07935 b2c1798d76c5d2ab1adc5475c5e3a22f 266 Gene3D G3DSA:3.40.830.10 6 263 8.9E-85 T 14-10-2018 TSH58p_30125 091d7a277e06b62b8289d37742240c33 250 SUPERFAMILY SSF52540 25 242 1.46E-30 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_30125 091d7a277e06b62b8289d37742240c33 250 ProDom PD023318 PLASMID VIRC1 CROWN TUMOR GALL TIORF154 RIORF166 107 215 4.0E-4 T 14-10-2018 TSH58p_30125 091d7a277e06b62b8289d37742240c33 250 Pfam PF07015 VirC1 protein 25 215 3.1E-20 T 14-10-2018 IPR009744 VirC1 TSH58p_30125 091d7a277e06b62b8289d37742240c33 250 Gene3D G3DSA:3.40.50.300 27 244 2.9E-35 T 14-10-2018 TSH58p_30125 091d7a277e06b62b8289d37742240c33 250 PIRSF PIRSF009320 25 250 1.9E-34 T 14-10-2018 TSH58p_29215 7ea5e342b9be8c5a144c924a35210c9d 397 Pfam PF13193 AMP-binding enzyme C-terminal domain 315 390 5.4E-8 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSH58p_29215 7ea5e342b9be8c5a144c924a35210c9d 397 Gene3D G3DSA:3.40.50.12780 13 296 5.4E-27 T 14-10-2018 TSH58p_29215 7ea5e342b9be8c5a144c924a35210c9d 397 Gene3D G3DSA:3.30.300.30 302 397 2.3E-13 T 14-10-2018 TSH58p_29215 7ea5e342b9be8c5a144c924a35210c9d 397 SUPERFAMILY SSF56801 16 394 1.1E-52 T 14-10-2018 TSH58p_29215 7ea5e342b9be8c5a144c924a35210c9d 397 Pfam PF00501 AMP-binding enzyme 87 236 1.2E-16 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_01865 7eb95ce63d35d9e1db2193fa884ec8d4 328 Gene3D G3DSA:3.20.20.100 11 318 1.7E-65 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TSH58p_01865 7eb95ce63d35d9e1db2193fa884ec8d4 328 SUPERFAMILY SSF51430 12 317 5.37E-66 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TSH58p_01865 7eb95ce63d35d9e1db2193fa884ec8d4 328 Pfam PF00248 Aldo/keto reductase family 12 316 1.5E-49 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain TSH58p_31675 a1f7eba410663dcc0694a07b18743790 154 SUPERFAMILY SSF54427 2 154 4.79E-79 T 14-10-2018 IPR032710 NTF2-like domain superfamily TSH58p_31675 a1f7eba410663dcc0694a07b18743790 154 Pfam PF07080 Protein of unknown function (DUF1348) 7 136 2.7E-65 T 14-10-2018 IPR009783 Protein of unknown function DUF1348 TSH58p_31675 a1f7eba410663dcc0694a07b18743790 154 Gene3D G3DSA:3.10.450.50 10 154 3.2E-75 T 14-10-2018 TSH58p_15440 466c10eb03a9eb62f90cd86fe31e31a4 236 Pfam PF04344 Chemotaxis phosphatase, CheZ 126 235 9.5E-12 T 14-10-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 TSH58p_15440 466c10eb03a9eb62f90cd86fe31e31a4 236 SUPERFAMILY SSF75708 56 235 1.57E-37 T 14-10-2018 TSH58p_15440 466c10eb03a9eb62f90cd86fe31e31a4 236 Gene3D G3DSA:1.10.287.500 121 170 8.9E-8 T 14-10-2018 TSH58p_19950 7842039c148552e5b3c284b1a02a492d 543 Gene3D G3DSA:1.10.20.110 38 404 2.8E-211 T 14-10-2018 TSH58p_19950 7842039c148552e5b3c284b1a02a492d 543 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 312 325 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TSH58p_19950 7842039c148552e5b3c284b1a02a492d 543 Gene3D G3DSA:3.40.640.10 162 382 2.8E-211 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_19950 7842039c148552e5b3c284b1a02a492d 543 Gene3D G3DSA:3.90.1150.10 31 524 2.8E-211 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_19950 7842039c148552e5b3c284b1a02a492d 543 TIGRFAM TIGR03801 asp_4_decarbox: aspartate 4-decarboxylase 12 526 2.9E-235 T 14-10-2018 IPR022518 Aspartate 4-decarboxylase KEGG: 00220+2.6.1.1|KEGG: 00250+4.1.1.12+2.6.1.1|KEGG: 00270+4.1.1.12+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 TSH58p_19950 7842039c148552e5b3c284b1a02a492d 543 SUPERFAMILY SSF53383 128 511 1.71E-40 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_19950 7842039c148552e5b3c284b1a02a492d 543 Pfam PF00155 Aminotransferase class I and II 191 508 8.0E-21 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSH58p_25075 57c019ae02d1d5b5e283dd16067c0c5f 608 SUPERFAMILY SSF48452 99 287 1.43E-31 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25075 57c019ae02d1d5b5e283dd16067c0c5f 608 SUPERFAMILY SSF48452 9 135 3.22E-25 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25075 57c019ae02d1d5b5e283dd16067c0c5f 608 Pfam PF13424 Tetratricopeptide repeat 86 146 5.6E-8 T 14-10-2018 TSH58p_25075 57c019ae02d1d5b5e283dd16067c0c5f 608 Pfam PF13424 Tetratricopeptide repeat 186 248 7.5E-10 T 14-10-2018 TSH58p_25075 57c019ae02d1d5b5e283dd16067c0c5f 608 Gene3D G3DSA:1.25.40.10 150 317 7.7E-34 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25075 57c019ae02d1d5b5e283dd16067c0c5f 608 SUPERFAMILY SSF53756 339 586 2.07E-22 T 14-10-2018 TSH58p_25075 57c019ae02d1d5b5e283dd16067c0c5f 608 Gene3D G3DSA:1.25.40.10 5 149 4.9E-33 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_25075 57c019ae02d1d5b5e283dd16067c0c5f 608 Gene3D G3DSA:3.40.50.2000 490 590 3.1E-6 T 14-10-2018 TSH58p_25075 57c019ae02d1d5b5e283dd16067c0c5f 608 SMART SM00028 252 285 4.2 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25075 57c019ae02d1d5b5e283dd16067c0c5f 608 SMART SM00028 218 251 0.0047 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25075 57c019ae02d1d5b5e283dd16067c0c5f 608 SMART SM00028 48 81 2.1 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25075 57c019ae02d1d5b5e283dd16067c0c5f 608 SMART SM00028 14 47 0.96 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25075 57c019ae02d1d5b5e283dd16067c0c5f 608 SMART SM00028 116 149 0.96 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25075 57c019ae02d1d5b5e283dd16067c0c5f 608 SMART SM00028 184 217 4.1E-6 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25075 57c019ae02d1d5b5e283dd16067c0c5f 608 SMART SM00028 82 115 2.1E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_25075 57c019ae02d1d5b5e283dd16067c0c5f 608 Pfam PF13432 Tetratricopeptide repeat 19 81 5.8E-10 T 14-10-2018 TSH58p_02070 874e4c3dcdfd3bfdb5d0a19b5dfc5da3 617 Gene3D G3DSA:1.10.287.130 389 451 8.0E-20 T 14-10-2018 TSH58p_02070 874e4c3dcdfd3bfdb5d0a19b5dfc5da3 617 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 497 609 1.3E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_02070 874e4c3dcdfd3bfdb5d0a19b5dfc5da3 617 SMART SM00388 384 454 9.6E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_02070 874e4c3dcdfd3bfdb5d0a19b5dfc5da3 617 SMART SM00387 496 611 5.4E-33 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_02070 874e4c3dcdfd3bfdb5d0a19b5dfc5da3 617 Gene3D G3DSA:3.40.190.10 34 265 1.0E-16 T 14-10-2018 TSH58p_02070 874e4c3dcdfd3bfdb5d0a19b5dfc5da3 617 SUPERFAMILY SSF55874 452 609 6.16E-40 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_02070 874e4c3dcdfd3bfdb5d0a19b5dfc5da3 617 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 33 281 1.2E-35 T 14-10-2018 TSH58p_02070 874e4c3dcdfd3bfdb5d0a19b5dfc5da3 617 Gene3D G3DSA:3.40.190.10 119 240 1.0E-16 T 14-10-2018 TSH58p_02070 874e4c3dcdfd3bfdb5d0a19b5dfc5da3 617 PRINTS PR00344 Bacterial sensor protein C-terminal signature 571 589 3.5E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_02070 874e4c3dcdfd3bfdb5d0a19b5dfc5da3 617 PRINTS PR00344 Bacterial sensor protein C-terminal signature 542 556 3.5E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_02070 874e4c3dcdfd3bfdb5d0a19b5dfc5da3 617 PRINTS PR00344 Bacterial sensor protein C-terminal signature 560 570 3.5E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_02070 874e4c3dcdfd3bfdb5d0a19b5dfc5da3 617 PRINTS PR00344 Bacterial sensor protein C-terminal signature 595 608 3.5E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_02070 874e4c3dcdfd3bfdb5d0a19b5dfc5da3 617 SUPERFAMILY SSF53850 68 215 6.59E-14 T 14-10-2018 TSH58p_02070 874e4c3dcdfd3bfdb5d0a19b5dfc5da3 617 Pfam PF00512 His Kinase A (phospho-acceptor) domain 385 452 2.2E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_02070 874e4c3dcdfd3bfdb5d0a19b5dfc5da3 617 Gene3D G3DSA:3.30.565.10 454 616 1.1E-43 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_02070 874e4c3dcdfd3bfdb5d0a19b5dfc5da3 617 SUPERFAMILY SSF47384 380 451 1.59E-9 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_30735 c3fd3e204853b7e20c5e908ac303c003 327 Gene3D G3DSA:1.10.3720.10 83 315 1.6E-19 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_30735 c3fd3e204853b7e20c5e908ac303c003 327 SUPERFAMILY SSF161098 91 304 1.79E-14 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_30735 c3fd3e204853b7e20c5e908ac303c003 327 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 318 4.8E-33 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_19825 4c889bbe831ee9f1b0dd0f49030ee1a5 174 SUPERFAMILY SSF110087 12 153 1.44E-50 T 14-10-2018 IPR036182 Copper chaperone PCuAC superfamily TSH58p_19825 4c889bbe831ee9f1b0dd0f49030ee1a5 174 Pfam PF04314 Copper chaperone PCu(A)C 37 145 8.7E-40 T 14-10-2018 IPR007410 Copper chaperone PCuAC TSH58p_19825 4c889bbe831ee9f1b0dd0f49030ee1a5 174 Gene3D G3DSA:2.60.40.1890 41 154 2.4E-39 T 14-10-2018 IPR036182 Copper chaperone PCuAC superfamily TSH58p_20485 1b47972c06239936a71c61e91c9bbba2 341 SMART SM00382 56 252 1.7E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_20485 1b47972c06239936a71c61e91c9bbba2 341 SUPERFAMILY SSF52540 19 254 3.09E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_20485 1b47972c06239936a71c61e91c9bbba2 341 Gene3D G3DSA:3.40.50.300 21 264 1.2E-67 T 14-10-2018 TSH58p_20485 1b47972c06239936a71c61e91c9bbba2 341 Pfam PF00005 ABC transporter 47 189 5.6E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_20485 1b47972c06239936a71c61e91c9bbba2 341 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_20190 a56eaccaccd40c81e37d37c72747b4e0 216 Pfam PF03963 Flagellar hook capping protein - N-terminal region 3 71 2.2E-22 T 14-10-2018 IPR005648 Flagellar hook capping protein TSH58p_20190 a56eaccaccd40c81e37d37c72747b4e0 216 Pfam PF13860 FlgD Ig-like domain 98 171 4.4E-16 T 14-10-2018 IPR025965 FlgD Ig-like domain TSH58p_20190 a56eaccaccd40c81e37d37c72747b4e0 216 Gene3D G3DSA:2.30.30.910 89 208 4.9E-20 T 14-10-2018 TSH58p_20190 a56eaccaccd40c81e37d37c72747b4e0 216 Gene3D G3DSA:2.60.40.4070 97 182 4.9E-20 T 14-10-2018 TSH58p_06790 aba34f3676bb98b56ba4345c25e98603 356 SUPERFAMILY SSF46548 136 253 3.5E-19 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSH58p_06790 aba34f3676bb98b56ba4345c25e98603 356 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 5 312 46.548 T 14-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 TSH58p_06790 aba34f3676bb98b56ba4345c25e98603 356 Pfam PF13484 4Fe-4S double cluster binding domain 189 253 1.9E-19 T 14-10-2018 TSH58p_06790 aba34f3676bb98b56ba4345c25e98603 356 Pfam PF08331 Domain of unknown function (DUF1730) 61 137 7.3E-23 T 14-10-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 TSH58p_06790 aba34f3676bb98b56ba4345c25e98603 356 SUPERFAMILY SSF48371 302 349 7.67E-5 T 14-10-2018 IPR016024 Armadillo-type fold TSH58p_06790 aba34f3676bb98b56ba4345c25e98603 356 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 12 344 7.9E-141 T 14-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 TSH58p_06790 aba34f3676bb98b56ba4345c25e98603 356 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 190 201 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_06790 aba34f3676bb98b56ba4345c25e98603 356 Gene3D G3DSA:1.25.10.110 300 354 3.3E-5 T 14-10-2018 TSH58p_05090 9fa29ac2c21905b7e0adfb79674dce57 487 Gene3D G3DSA:3.20.20.60 5 332 1.5E-161 T 14-10-2018 TSH58p_05090 9fa29ac2c21905b7e0adfb79674dce57 487 SUPERFAMILY SSF50800 73 167 2.97E-24 T 14-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily TSH58p_05090 9fa29ac2c21905b7e0adfb79674dce57 487 SUPERFAMILY SSF52935 320 470 4.84E-36 T 14-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_05090 9fa29ac2c21905b7e0adfb79674dce57 487 PRINTS PR01050 Pyruvate kinase family signature 187 201 7.5E-63 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_05090 9fa29ac2c21905b7e0adfb79674dce57 487 PRINTS PR01050 Pyruvate kinase family signature 291 309 7.5E-63 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_05090 9fa29ac2c21905b7e0adfb79674dce57 487 PRINTS PR01050 Pyruvate kinase family signature 310 326 7.5E-63 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_05090 9fa29ac2c21905b7e0adfb79674dce57 487 PRINTS PR01050 Pyruvate kinase family signature 62 78 7.5E-63 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_05090 9fa29ac2c21905b7e0adfb79674dce57 487 PRINTS PR01050 Pyruvate kinase family signature 266 290 7.5E-63 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_05090 9fa29ac2c21905b7e0adfb79674dce57 487 PRINTS PR01050 Pyruvate kinase family signature 214 240 7.5E-63 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_05090 9fa29ac2c21905b7e0adfb79674dce57 487 PRINTS PR01050 Pyruvate kinase family signature 241 265 7.5E-63 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_05090 9fa29ac2c21905b7e0adfb79674dce57 487 Gene3D G3DSA:2.40.33.10 73 169 1.5E-161 T 14-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_05090 9fa29ac2c21905b7e0adfb79674dce57 487 Pfam PF02887 Pyruvate kinase, alpha/beta domain 355 468 6.2E-29 T 14-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_05090 9fa29ac2c21905b7e0adfb79674dce57 487 Gene3D G3DSA:3.40.1380.20 333 466 1.5E-161 T 14-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_05090 9fa29ac2c21905b7e0adfb79674dce57 487 SUPERFAMILY SSF51621 2 340 5.23E-94 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSH58p_05090 9fa29ac2c21905b7e0adfb79674dce57 487 Pfam PF00224 Pyruvate kinase, barrel domain 5 334 3.2E-109 T 14-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_05090 9fa29ac2c21905b7e0adfb79674dce57 487 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 5 470 1.6E-144 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSH58p_31475 363ef3e35dbfcca6074d697b263a7e86 317 Pfam PF13407 Periplasmic binding protein domain 31 278 7.7E-38 T 14-10-2018 IPR025997 Periplasmic binding protein TSH58p_31475 363ef3e35dbfcca6074d697b263a7e86 317 Gene3D G3DSA:3.40.50.2300 31 298 2.5E-95 T 14-10-2018 TSH58p_31475 363ef3e35dbfcca6074d697b263a7e86 317 Gene3D G3DSA:3.40.50.2300 136 310 2.5E-95 T 14-10-2018 TSH58p_31475 363ef3e35dbfcca6074d697b263a7e86 317 SUPERFAMILY SSF53822 8 311 5.89E-63 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_32150 6210036917e31588db18e3e89f2f46fa 263 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_32150 6210036917e31588db18e3e89f2f46fa 263 SMART SM00382 41 221 1.3E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_32150 6210036917e31588db18e3e89f2f46fa 263 Gene3D G3DSA:3.40.50.300 12 254 6.6E-66 T 14-10-2018 TSH58p_32150 6210036917e31588db18e3e89f2f46fa 263 SUPERFAMILY SSF52540 14 237 1.98E-69 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_32150 6210036917e31588db18e3e89f2f46fa 263 Pfam PF00005 ABC transporter 32 170 3.1E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_24500 b92ce524a4a31a56630ddd3ad5644668 720 Gene3D G3DSA:1.25.40.10 2 77 2.9E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_24500 b92ce524a4a31a56630ddd3ad5644668 720 Gene3D G3DSA:1.25.40.10 78 113 3.5E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_24500 b92ce524a4a31a56630ddd3ad5644668 720 Gene3D G3DSA:1.25.40.10 114 147 1.3E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_24500 b92ce524a4a31a56630ddd3ad5644668 720 SUPERFAMILY SSF48452 9 241 3.32E-36 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_24500 b92ce524a4a31a56630ddd3ad5644668 720 SUPERFAMILY SSF53756 366 694 5.81E-6 T 14-10-2018 TSH58p_24500 b92ce524a4a31a56630ddd3ad5644668 720 SUPERFAMILY SSF48452 222 319 1.71E-18 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_24500 b92ce524a4a31a56630ddd3ad5644668 720 Pfam PF13844 Glycosyl transferase family 41 530 709 3.7E-22 T 14-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 TSH58p_24500 b92ce524a4a31a56630ddd3ad5644668 720 Pfam PF13844 Glycosyl transferase family 41 364 510 1.4E-16 T 14-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 TSH58p_24500 b92ce524a4a31a56630ddd3ad5644668 720 Gene3D G3DSA:3.40.50.2000 520 699 4.0E-118 T 14-10-2018 TSH58p_24500 b92ce524a4a31a56630ddd3ad5644668 720 Gene3D G3DSA:3.40.50.11380 350 703 4.0E-118 T 14-10-2018 TSH58p_24500 b92ce524a4a31a56630ddd3ad5644668 720 Gene3D G3DSA:1.25.40.10 148 317 8.8E-34 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_24500 b92ce524a4a31a56630ddd3ad5644668 720 Pfam PF13414 TPR repeat 249 290 1.1E-6 T 14-10-2018 TSH58p_24500 b92ce524a4a31a56630ddd3ad5644668 720 Pfam PF00515 Tetratricopeptide repeat 106 139 9.4E-8 T 14-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 TSH58p_24500 b92ce524a4a31a56630ddd3ad5644668 720 Pfam PF14559 Tetratricopeptide repeat 16 71 1.8E-5 T 14-10-2018 TSH58p_24500 b92ce524a4a31a56630ddd3ad5644668 720 Pfam PF14559 Tetratricopeptide repeat 152 214 1.6E-5 T 14-10-2018 TSH58p_24500 b92ce524a4a31a56630ddd3ad5644668 720 SMART SM00028 106 139 1.4E-6 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24500 b92ce524a4a31a56630ddd3ad5644668 720 SMART SM00028 4 37 120.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24500 b92ce524a4a31a56630ddd3ad5644668 720 SMART SM00028 38 71 11.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24500 b92ce524a4a31a56630ddd3ad5644668 720 SMART SM00028 72 105 0.81 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24500 b92ce524a4a31a56630ddd3ad5644668 720 SMART SM00028 208 241 57.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24500 b92ce524a4a31a56630ddd3ad5644668 720 SMART SM00028 140 173 0.069 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24500 b92ce524a4a31a56630ddd3ad5644668 720 SMART SM00028 174 207 0.38 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24500 b92ce524a4a31a56630ddd3ad5644668 720 SMART SM00028 276 309 7.9E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24500 b92ce524a4a31a56630ddd3ad5644668 720 SMART SM00028 242 275 3.7 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_11630 fa504649e46cf80056aa0ec5f0fc1c0e 53 Pfam PF05545 Cbb3-type cytochrome oxidase component FixQ 1 49 6.4E-19 T 14-10-2018 IPR008621 Cbb3-type cytochrome oxidase component TSH58p_28765 17e958fdf75be131f3f637ed86fe8aed 253 PIRSF PIRSF005457 1 253 5.7E-110 T 14-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 TSH58p_28765 17e958fdf75be131f3f637ed86fe8aed 253 Pfam PF00753 Metallo-beta-lactamase superfamily 22 169 2.7E-21 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_28765 17e958fdf75be131f3f637ed86fe8aed 253 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 3 253 2.2E-103 T 14-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 TSH58p_28765 17e958fdf75be131f3f637ed86fe8aed 253 Gene3D G3DSA:3.60.15.10 1 253 9.0E-91 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_28765 17e958fdf75be131f3f637ed86fe8aed 253 SMART SM00849 11 169 7.5E-37 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_28765 17e958fdf75be131f3f637ed86fe8aed 253 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 1 253 44.531 T 14-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 TSH58p_28765 17e958fdf75be131f3f637ed86fe8aed 253 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 170 253 2.3E-28 T 14-10-2018 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 TSH58p_28765 17e958fdf75be131f3f637ed86fe8aed 253 SUPERFAMILY SSF56281 1 253 2.98E-75 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_14985 c32607612eab6b27ead89e8a59b3ff01 383 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 3 379 3.4E-97 T 14-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 TSH58p_14985 c32607612eab6b27ead89e8a59b3ff01 383 PIRSF PIRSF038994 3 383 2.6E-107 T 14-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 TSH58p_14985 c32607612eab6b27ead89e8a59b3ff01 383 Gene3D G3DSA:2.30.40.10 9 378 5.5E-125 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_14985 c32607612eab6b27ead89e8a59b3ff01 383 Gene3D G3DSA:3.20.20.140 55 346 5.5E-125 T 14-10-2018 TSH58p_14985 c32607612eab6b27ead89e8a59b3ff01 383 SUPERFAMILY SSF51338 2 53 9.84E-13 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_14985 c32607612eab6b27ead89e8a59b3ff01 383 Pfam PF01979 Amidohydrolase family 50 380 4.8E-20 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TSH58p_14985 c32607612eab6b27ead89e8a59b3ff01 383 SUPERFAMILY SSF51556 54 352 6.28E-96 T 14-10-2018 IPR032466 Metal-dependent hydrolase TSH58p_06280 c50b6d77bb06d4770e44128b4287921a 292 Gene3D G3DSA:3.40.50.150 31 223 1.9E-14 T 14-10-2018 TSH58p_06280 c50b6d77bb06d4770e44128b4287921a 292 Pfam PF08241 Methyltransferase domain 86 176 5.0E-7 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TSH58p_06280 c50b6d77bb06d4770e44128b4287921a 292 SUPERFAMILY SSF53335 46 227 2.64E-16 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_16760 c8d2f7508da6a27345c57bb19597d0e4 258 Pfam PF04333 MlaA lipoprotein 40 236 2.9E-67 T 14-10-2018 IPR007428 MlaA lipoprotein GO:0016020 TSH58p_16760 c8d2f7508da6a27345c57bb19597d0e4 258 PRINTS PR01805 VacJ lipoprotein signature 145 162 8.4E-22 T 14-10-2018 IPR007428 MlaA lipoprotein GO:0016020 TSH58p_16760 c8d2f7508da6a27345c57bb19597d0e4 258 PRINTS PR01805 VacJ lipoprotein signature 41 54 8.4E-22 T 14-10-2018 IPR007428 MlaA lipoprotein GO:0016020 TSH58p_16760 c8d2f7508da6a27345c57bb19597d0e4 258 PRINTS PR01805 VacJ lipoprotein signature 109 126 8.4E-22 T 14-10-2018 IPR007428 MlaA lipoprotein GO:0016020 TSH58p_16760 c8d2f7508da6a27345c57bb19597d0e4 258 PRINTS PR01805 VacJ lipoprotein signature 58 74 8.4E-22 T 14-10-2018 IPR007428 MlaA lipoprotein GO:0016020 TSH58p_22425 6e21b60b9478584fbeb9aa1f81442717 246 Gene3D G3DSA:2.60.120.620 15 238 3.7E-8 T 14-10-2018 TSH58p_23160 7497b65c27f5f152c2a177fe9d0715b1 788 Pfam PF10593 Z1 domain 342 560 2.6E-59 T 14-10-2018 IPR018310 Putative endonuclease, Z1 domain TSH58p_02410 808c66792b1af565d2260200727b670a 355 SUPERFAMILY SSF52172 2 156 3.13E-32 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_02410 808c66792b1af565d2260200727b670a 355 Gene3D G3DSA:1.10.3210.10 142 344 3.4E-73 T 14-10-2018 TSH58p_02410 808c66792b1af565d2260200727b670a 355 SMART SM00448 1 115 1.4E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_02410 808c66792b1af565d2260200727b670a 355 SMART SM00471 164 301 9.2E-9 T 14-10-2018 IPR003607 HD/PDEase domain TSH58p_02410 808c66792b1af565d2260200727b670a 355 Pfam PF00072 Response regulator receiver domain 3 115 1.2E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_02410 808c66792b1af565d2260200727b670a 355 Gene3D G3DSA:3.40.50.2300 1 137 1.6E-28 T 14-10-2018 TSH58p_02410 808c66792b1af565d2260200727b670a 355 Pfam PF13487 HD domain 219 282 9.3E-18 T 14-10-2018 TSH58p_02410 808c66792b1af565d2260200727b670a 355 SUPERFAMILY SSF109604 155 329 5.65E-40 T 14-10-2018 TSH58p_28295 63c7d6b3459830608ba64ad2c966bb95 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 227 241 3.7E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_28295 63c7d6b3459830608ba64ad2c966bb95 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 115 3.7E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_28295 63c7d6b3459830608ba64ad2c966bb95 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 56 71 3.7E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_28295 63c7d6b3459830608ba64ad2c966bb95 283 SUPERFAMILY SSF53474 17 274 1.37E-47 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_28295 63c7d6b3459830608ba64ad2c966bb95 283 Pfam PF12697 Alpha/beta hydrolase family 33 275 2.2E-20 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_28295 63c7d6b3459830608ba64ad2c966bb95 283 Gene3D G3DSA:3.40.50.1820 5 281 1.0E-79 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_19645 262d344ffd59910849c003d4e1ecd163 169 Pfam PF14196 L-2-amino-thiazoline-4-carboxylic acid hydrolase 10 150 3.1E-21 T 14-10-2018 IPR026002 L-2-amino-thiazoline-4-carboxylic acid hydrolase TSH58p_26765 ef4c52c54a73dfb9cf192ab3ffc11b18 263 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 256 5.5E-49 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_26765 ef4c52c54a73dfb9cf192ab3ffc11b18 263 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 61 74 - T 14-10-2018 IPR018313 Solute-binding protein family 3, conserved site TSH58p_26765 ef4c52c54a73dfb9cf192ab3ffc11b18 263 Gene3D G3DSA:3.40.190.10 33 250 2.0E-53 T 14-10-2018 TSH58p_26765 ef4c52c54a73dfb9cf192ab3ffc11b18 263 Gene3D G3DSA:3.40.190.10 125 216 2.0E-53 T 14-10-2018 TSH58p_26765 ef4c52c54a73dfb9cf192ab3ffc11b18 263 SUPERFAMILY SSF53850 1 258 1.75E-55 T 14-10-2018 TSH58p_26765 ef4c52c54a73dfb9cf192ab3ffc11b18 263 SMART SM00062 38 258 1.4E-41 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_19300 9926777d1e26b214da9f796ee08315c9 280 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_19300 9926777d1e26b214da9f796ee08315c9 280 Gene3D G3DSA:3.40.50.300 4 259 5.2E-68 T 14-10-2018 TSH58p_19300 9926777d1e26b214da9f796ee08315c9 280 SMART SM00382 29 221 3.9E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_19300 9926777d1e26b214da9f796ee08315c9 280 SUPERFAMILY SSF52540 5 234 3.3E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_19300 9926777d1e26b214da9f796ee08315c9 280 Pfam PF00005 ABC transporter 23 169 2.3E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_20320 3bc68819a02c15b91ec602665976cfc3 254 Gene3D G3DSA:3.40.50.720 10 253 2.9E-79 T 14-10-2018 TSH58p_20320 3bc68819a02c15b91ec602665976cfc3 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 2.4E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_20320 3bc68819a02c15b91ec602665976cfc3 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 2.4E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_20320 3bc68819a02c15b91ec602665976cfc3 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 2.4E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_20320 3bc68819a02c15b91ec602665976cfc3 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 3.3E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_20320 3bc68819a02c15b91ec602665976cfc3 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 3.3E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_20320 3bc68819a02c15b91ec602665976cfc3 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 3.3E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_20320 3bc68819a02c15b91ec602665976cfc3 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 3.3E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_20320 3bc68819a02c15b91ec602665976cfc3 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 3.3E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_20320 3bc68819a02c15b91ec602665976cfc3 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 3.3E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_20320 3bc68819a02c15b91ec602665976cfc3 254 TIGRFAM TIGR01832 kduD: 2-deoxy-D-gluconate 3-dehydrogenase 7 254 4.2E-124 T 14-10-2018 IPR011286 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase GO:0008678|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.127|MetaCyc: PWY-6507|MetaCyc: PWY-7562 TSH58p_20320 3bc68819a02c15b91ec602665976cfc3 254 SUPERFAMILY SSF51735 6 253 8.16E-78 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_20320 3bc68819a02c15b91ec602665976cfc3 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_20320 3bc68819a02c15b91ec602665976cfc3 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 251 7.7E-60 T 14-10-2018 TSH58p_29035 0dce734991e2b3bc37050332353d376e 333 Pfam PF00248 Aldo/keto reductase family 16 306 7.9E-64 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain TSH58p_29035 0dce734991e2b3bc37050332353d376e 333 Gene3D G3DSA:3.20.20.100 1 331 3.4E-105 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TSH58p_29035 0dce734991e2b3bc37050332353d376e 333 SUPERFAMILY SSF51430 1 308 6.94E-89 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TSH58p_29035 0dce734991e2b3bc37050332353d376e 333 PRINTS PR00069 Aldo-keto reductase signature 240 264 4.9E-5 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TSH58p_29035 0dce734991e2b3bc37050332353d376e 333 PRINTS PR00069 Aldo-keto reductase signature 109 127 4.9E-5 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TSH58p_29035 0dce734991e2b3bc37050332353d376e 333 PRINTS PR00069 Aldo-keto reductase signature 140 157 4.9E-5 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TSH58p_12380 2c03ac81f728b157f5d03277e67a8424 228 Pfam PF01738 Dienelactone hydrolase family 24 227 1.0E-36 T 14-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 TSH58p_12380 2c03ac81f728b157f5d03277e67a8424 228 Gene3D G3DSA:3.40.50.1820 11 226 2.2E-44 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_12380 2c03ac81f728b157f5d03277e67a8424 228 SUPERFAMILY SSF53474 13 225 1.46E-35 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_27540 57a0543af5b668f2b648f827ae4ebe8c 448 SMART SM00382 160 344 9.4E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_27540 57a0543af5b668f2b648f827ae4ebe8c 448 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 9 439 6.4E-160 T 14-10-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSH58p_27540 57a0543af5b668f2b648f827ae4ebe8c 448 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 350 359 - T 14-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSH58p_27540 57a0543af5b668f2b648f827ae4ebe8c 448 Gene3D G3DSA:3.40.50.12240 13 442 3.5E-141 T 14-10-2018 TSH58p_27540 57a0543af5b668f2b648f827ae4ebe8c 448 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 24 84 5.1E-4 T 14-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSH58p_27540 57a0543af5b668f2b648f827ae4ebe8c 448 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 148 359 1.7E-71 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSH58p_27540 57a0543af5b668f2b648f827ae4ebe8c 448 SUPERFAMILY SSF52540 96 363 1.13E-90 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_27540 57a0543af5b668f2b648f827ae4ebe8c 448 TIGRFAM TIGR03498 FliI_clade3: flagellar protein export ATPase FliI 22 438 3.3E-198 T 14-10-2018 IPR022426 Flagellum-specific ATP synthase FliI, clade 3 GO:0009288|GO:0016887|GO:0030257|GO:0044781 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSH58p_11460 39be920dcd9c662a5473daf232d6e161 143 Gene3D G3DSA:1.10.10.10 9 90 7.6E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_11460 39be920dcd9c662a5473daf232d6e161 143 Pfam PF01475 Ferric uptake regulator family 17 112 4.6E-20 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 TSH58p_11460 39be920dcd9c662a5473daf232d6e161 143 SUPERFAMILY SSF46785 9 132 8.4E-28 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_03355 e8a6a8fdbf103fa9b1b29e934b3b2b6d 330 Gene3D G3DSA:3.30.420.300 7 89 7.8E-24 T 14-10-2018 TSH58p_03355 e8a6a8fdbf103fa9b1b29e934b3b2b6d 330 Gene3D G3DSA:3.30.420.310 90 322 1.6E-62 T 14-10-2018 TSH58p_03355 e8a6a8fdbf103fa9b1b29e934b3b2b6d 330 Pfam PF05035 2-keto-3-deoxy-galactonokinase 16 317 1.6E-90 T 14-10-2018 IPR007729 2-keto-3-deoxy-galactonokinase GO:0008671|GO:0034194 KEGG: 00052+2.7.1.58|MetaCyc: PWY-7130 TSH58p_13510 250e7b2fd74991498a34197528d66b73 90 Pfam PF07362 Post-segregation antitoxin CcdA 20 90 7.2E-26 T 14-10-2018 IPR009956 Post-segregation antitoxin CcdA TSH58p_26220 505e222d5ddda2f3f1c59b7efbdb6eb3 267 Gene3D G3DSA:3.40.50.300 1 245 6.5E-66 T 14-10-2018 TSH58p_26220 505e222d5ddda2f3f1c59b7efbdb6eb3 267 Pfam PF00005 ABC transporter 18 167 1.6E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_26220 505e222d5ddda2f3f1c59b7efbdb6eb3 267 SUPERFAMILY SSF52540 3 231 1.49E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_26220 505e222d5ddda2f3f1c59b7efbdb6eb3 267 SMART SM00382 27 214 4.9E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_26220 505e222d5ddda2f3f1c59b7efbdb6eb3 267 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_22605 c4ad3b326bc95cd2efb966492a2d6ff6 333 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 124 249 5.5E-29 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSH58p_22605 c4ad3b326bc95cd2efb966492a2d6ff6 333 Gene3D G3DSA:3.40.50.300 69 266 4.1E-45 T 14-10-2018 TSH58p_22605 c4ad3b326bc95cd2efb966492a2d6ff6 333 SUPERFAMILY SSF52540 81 319 9.59E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_22605 c4ad3b326bc95cd2efb966492a2d6ff6 333 SMART SM00382 120 253 1.9E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_02135 7e4b5ecfadcbc2c7020020e772023cb8 297 Gene3D G3DSA:1.10.10.10 1 90 7.3E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_02135 7e4b5ecfadcbc2c7020020e772023cb8 297 SUPERFAMILY SSF53850 91 295 2.48E-41 T 14-10-2018 TSH58p_02135 7e4b5ecfadcbc2c7020020e772023cb8 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 9.2E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_02135 7e4b5ecfadcbc2c7020020e772023cb8 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 9.2E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_02135 7e4b5ecfadcbc2c7020020e772023cb8 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 9.2E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_02135 7e4b5ecfadcbc2c7020020e772023cb8 297 SUPERFAMILY SSF46785 1 112 1.29E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_02135 7e4b5ecfadcbc2c7020020e772023cb8 297 Gene3D G3DSA:3.40.190.290 91 292 9.8E-49 T 14-10-2018 TSH58p_02135 7e4b5ecfadcbc2c7020020e772023cb8 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 2.8E-24 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_02135 7e4b5ecfadcbc2c7020020e772023cb8 297 Pfam PF03466 LysR substrate binding domain 89 291 2.4E-38 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_24945 cdcfe6fe75fcda09c89bebabb90cb038 566 Gene3D G3DSA:3.40.50.720 402 562 5.1E-40 T 14-10-2018 TSH58p_24945 cdcfe6fe75fcda09c89bebabb90cb038 566 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 14 285 1.6E-76 T 14-10-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 TSH58p_24945 cdcfe6fe75fcda09c89bebabb90cb038 566 SUPERFAMILY SSF51735 401 544 1.08E-33 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_24945 cdcfe6fe75fcda09c89bebabb90cb038 566 Pfam PF02254 TrkA-N domain 405 518 4.1E-24 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TSH58p_24945 cdcfe6fe75fcda09c89bebabb90cb038 566 Gene3D G3DSA:1.20.1530.20 3 387 5.5E-82 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily TSH58p_24945 cdcfe6fe75fcda09c89bebabb90cb038 566 Pfam PF00999 Sodium/hydrogen exchanger family 11 373 4.1E-66 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TSH58p_07735 66824beca72297fe8da3d2ea44e307cd 107 PIRSF PIRSF005790 1 107 1.3E-40 T 14-10-2018 IPR004893 Nitrogen fixation protein NifW GO:0009399 TSH58p_07735 66824beca72297fe8da3d2ea44e307cd 107 Hamap MF_00529 Nitrogenase-stabilizing/protective protein NifW [nifW]. 1 105 23.697 T 14-10-2018 IPR004893 Nitrogen fixation protein NifW GO:0009399 TSH58p_07735 66824beca72297fe8da3d2ea44e307cd 107 Pfam PF03206 Nitrogen fixation protein NifW 4 104 3.6E-35 T 14-10-2018 IPR004893 Nitrogen fixation protein NifW GO:0009399 TSH58p_30165 7d150c5a4a645236dd7342441f50bc87 249 Pfam PF07592 Rhodopirellula transposase DDE domain 110 233 4.0E-33 T 14-10-2018 IPR011518 Transposase, Rhodopirellula-type TSH58p_30005 7d150c5a4a645236dd7342441f50bc87 249 Pfam PF07592 Rhodopirellula transposase DDE domain 110 233 4.0E-33 T 14-10-2018 IPR011518 Transposase, Rhodopirellula-type TSH58p_21595 f8fa13eb2c89db03f06e3e2c1003be2b 305 Pfam PF00146 NADH dehydrogenase 3 298 3.6E-36 T 14-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_15745 4b586a2dd46e8f9580d1782a3933446d 1127 Pfam PF08455 Bacterial SNF2 helicase associated 402 645 1.5E-7 T 14-10-2018 IPR013663 Helicase, SWF/SNF/SWI type, bacterial TSH58p_15745 4b586a2dd46e8f9580d1782a3933446d 1127 Gene3D G3DSA:3.40.50.10810 664 875 2.6E-69 T 14-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily TSH58p_15745 4b586a2dd46e8f9580d1782a3933446d 1127 Pfam PF00271 Helicase conserved C-terminal domain 960 1069 3.9E-16 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_15745 4b586a2dd46e8f9580d1782a3933446d 1127 Pfam PF00176 SNF2 family N-terminal domain 679 947 1.1E-63 T 14-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 TSH58p_15745 4b586a2dd46e8f9580d1782a3933446d 1127 SUPERFAMILY SSF52540 875 1111 8.99E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_15745 4b586a2dd46e8f9580d1782a3933446d 1127 SMART SM00490 989 1069 2.6E-19 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_15745 4b586a2dd46e8f9580d1782a3933446d 1127 SUPERFAMILY SSF52540 627 874 3.64E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_15745 4b586a2dd46e8f9580d1782a3933446d 1127 SMART SM00487 659 843 1.9E-36 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSH58p_15745 4b586a2dd46e8f9580d1782a3933446d 1127 Gene3D G3DSA:1.20.120.850 896 1108 1.3E-75 T 14-10-2018 TSH58p_15745 4b586a2dd46e8f9580d1782a3933446d 1127 Gene3D G3DSA:3.40.50.300 881 1083 1.3E-75 T 14-10-2018 TSH58p_25565 6e13a792994fb657d6b3b631bc707886 118 Gene3D G3DSA:2.102.10.10 4 108 5.1E-26 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TSH58p_25565 6e13a792994fb657d6b3b631bc707886 118 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 6 104 1.1E-27 T 14-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 TSH58p_25565 6e13a792994fb657d6b3b631bc707886 118 Pfam PF00355 Rieske [2Fe-2S] domain 6 83 9.6E-15 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TSH58p_25565 6e13a792994fb657d6b3b631bc707886 118 SUPERFAMILY SSF50022 6 106 2.75E-33 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TSH58p_10155 c9af0f2e447dafb0f14dcdd1fdc5ec8e 298 SMART SM00382 34 233 3.6E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_10155 c9af0f2e447dafb0f14dcdd1fdc5ec8e 298 Pfam PF00005 ABC transporter 28 184 1.1E-21 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_10155 c9af0f2e447dafb0f14dcdd1fdc5ec8e 298 SUPERFAMILY SSF52540 6 246 1.97E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_10155 c9af0f2e447dafb0f14dcdd1fdc5ec8e 298 Gene3D G3DSA:3.40.50.300 4 290 8.3E-81 T 14-10-2018 TSH58p_26030 814bee06c0356adb902b0ba27f5d35fb 267 Pfam PF01061 ABC-2 type transporter 20 229 3.7E-32 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TSH58p_26030 814bee06c0356adb902b0ba27f5d35fb 267 PRINTS PR00164 ABC-2 type transport system membrane protein signature 187 206 5.0E-8 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSH58p_26030 814bee06c0356adb902b0ba27f5d35fb 267 PRINTS PR00164 ABC-2 type transport system membrane protein signature 69 91 5.0E-8 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSH58p_26030 814bee06c0356adb902b0ba27f5d35fb 267 PRINTS PR00164 ABC-2 type transport system membrane protein signature 207 226 5.0E-8 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSH58p_26030 814bee06c0356adb902b0ba27f5d35fb 267 PIRSF PIRSF006648 1 264 5.5E-23 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSH58p_06320 0a53f32c88d872e805350d5bb904b815 137 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 21 82 8.6E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_06320 0a53f32c88d872e805350d5bb904b815 137 SUPERFAMILY SSF46785 3 98 3.31E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_06320 0a53f32c88d872e805350d5bb904b815 137 Gene3D G3DSA:1.10.10.10 1 122 6.5E-36 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_04100 51630a2a16328aeaee033ee0741ab4e2 337 PIRSF PIRSF001415 5 337 1.3E-142 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TSH58p_04100 51630a2a16328aeaee033ee0741ab4e2 337 Gene3D G3DSA:3.20.20.70 4 337 2.7E-140 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_04100 51630a2a16328aeaee033ee0741ab4e2 337 SUPERFAMILY SSF51569 9 336 1.29E-137 T 14-10-2018 TSH58p_04100 51630a2a16328aeaee033ee0741ab4e2 337 SMART SM01004 12 334 1.1E-226 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TSH58p_04100 51630a2a16328aeaee033ee0741ab4e2 337 Pfam PF00490 Delta-aminolevulinic acid dehydratase 15 332 2.8E-136 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TSH58p_04100 51630a2a16328aeaee033ee0741ab4e2 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 253 269 3.8E-57 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TSH58p_04100 51630a2a16328aeaee033ee0741ab4e2 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 162 181 3.8E-57 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TSH58p_04100 51630a2a16328aeaee033ee0741ab4e2 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 132 146 3.8E-57 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TSH58p_04100 51630a2a16328aeaee033ee0741ab4e2 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 278 293 3.8E-57 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TSH58p_04100 51630a2a16328aeaee033ee0741ab4e2 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 200 219 3.8E-57 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TSH58p_04100 51630a2a16328aeaee033ee0741ab4e2 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 308 327 3.8E-57 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TSH58p_04100 51630a2a16328aeaee033ee0741ab4e2 337 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 253 265 - T 14-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TSH58p_04670 c7eec04875aa7e7bb6f59853220d5ea7 211 PIRSF PIRSF006324 1 210 3.6E-58 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 TSH58p_04670 c7eec04875aa7e7bb6f59853220d5ea7 211 Pfam PF01810 LysE type translocator 15 207 3.7E-34 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 TSH58p_18280 ff059b0938c5002f4d073e213f99195c 333 SUPERFAMILY SSF51735 9 329 2.69E-91 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_18280 ff059b0938c5002f4d073e213f99195c 333 Pfam PF01370 NAD dependent epimerase/dehydratase family 11 260 5.6E-57 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TSH58p_18280 ff059b0938c5002f4d073e213f99195c 333 Gene3D G3DSA:3.90.25.10 181 314 3.1E-121 T 14-10-2018 TSH58p_18280 ff059b0938c5002f4d073e213f99195c 333 Gene3D G3DSA:3.40.50.720 11 260 3.1E-121 T 14-10-2018 TSH58p_18280 ff059b0938c5002f4d073e213f99195c 333 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 10 329 2.8E-132 T 14-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 TSH58p_29270 6e6540aad508a481d2fc06a3344543fe 194 Pfam PF04972 BON domain 128 193 1.1E-11 T 14-10-2018 IPR007055 BON domain TSH58p_29270 6e6540aad508a481d2fc06a3344543fe 194 Pfam PF04972 BON domain 51 117 1.6E-13 T 14-10-2018 IPR007055 BON domain TSH58p_09470 0174293e7c7eff1e54d069d31c8b62d5 192 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 3 178 8.0E-63 T 14-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG TSH58p_09470 0174293e7c7eff1e54d069d31c8b62d5 192 Pfam PF03641 Possible lysine decarboxylase 45 173 1.9E-41 T 14-10-2018 IPR031100 LOG family TSH58p_09470 0174293e7c7eff1e54d069d31c8b62d5 192 SUPERFAMILY SSF102405 1 177 1.68E-62 T 14-10-2018 TSH58p_09470 0174293e7c7eff1e54d069d31c8b62d5 192 Gene3D G3DSA:3.40.50.450 1 192 3.1E-77 T 14-10-2018 TSH58p_08250 5635aa6f7435d6f3cb427dc992e6f71c 418 Gene3D G3DSA:3.40.50.2300 147 285 3.7E-72 T 14-10-2018 TSH58p_08250 5635aa6f7435d6f3cb427dc992e6f71c 418 Gene3D G3DSA:3.40.50.2300 30 355 3.7E-72 T 14-10-2018 TSH58p_08250 5635aa6f7435d6f3cb427dc992e6f71c 418 SUPERFAMILY SSF53822 27 399 1.04E-66 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_08250 5635aa6f7435d6f3cb427dc992e6f71c 418 Pfam PF13458 Periplasmic binding protein 28 393 7.6E-52 T 14-10-2018 IPR028081 Leucine-binding protein domain TSH58p_28775 d2970912c843e1da5df43fd4e5eb9fb4 187 SUPERFAMILY SSF53474 6 178 1.67E-31 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_28775 d2970912c843e1da5df43fd4e5eb9fb4 187 Gene3D G3DSA:3.40.50.1820 1 185 4.8E-53 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_28775 d2970912c843e1da5df43fd4e5eb9fb4 187 Pfam PF06821 Serine hydrolase 6 176 5.2E-61 T 14-10-2018 IPR010662 Putative hydrolase RBBP9/YdeN GO:0016787 TSH58p_13090 fce7c34e242cfca825df51239f422e70 264 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 25 259 1.2E-37 T 14-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 TSH58p_13090 fce7c34e242cfca825df51239f422e70 264 Pfam PF02654 Cobalamin-5-phosphate synthase 25 257 3.7E-49 T 14-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 TSH58p_13090 fce7c34e242cfca825df51239f422e70 264 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 264 48.419 T 14-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 TSH58p_13245 4ac339f0a6dfe6f7f7cf091b65e7ac6f 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 7.9E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_13245 4ac339f0a6dfe6f7f7cf091b65e7ac6f 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 7.9E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_13245 4ac339f0a6dfe6f7f7cf091b65e7ac6f 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 7.9E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_13245 4ac339f0a6dfe6f7f7cf091b65e7ac6f 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_13245 4ac339f0a6dfe6f7f7cf091b65e7ac6f 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.7E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_13245 4ac339f0a6dfe6f7f7cf091b65e7ac6f 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.7E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_13245 4ac339f0a6dfe6f7f7cf091b65e7ac6f 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.7E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_13245 4ac339f0a6dfe6f7f7cf091b65e7ac6f 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.7E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_13245 4ac339f0a6dfe6f7f7cf091b65e7ac6f 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.7E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_13245 4ac339f0a6dfe6f7f7cf091b65e7ac6f 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 1.7E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_13245 4ac339f0a6dfe6f7f7cf091b65e7ac6f 245 Gene3D G3DSA:3.40.50.720 4 244 1.6E-71 T 14-10-2018 TSH58p_13245 4ac339f0a6dfe6f7f7cf091b65e7ac6f 245 SUPERFAMILY SSF51735 5 244 4.9E-66 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_13245 4ac339f0a6dfe6f7f7cf091b65e7ac6f 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 243 8.8E-48 T 14-10-2018 TSH58p_12500 fad74a941c0f3f9dac3bf917683c80e5 187 Pfam PF12796 Ankyrin repeats (3 copies) 37 124 1.2E-15 T 14-10-2018 IPR020683 Ankyrin repeat-containing domain TSH58p_12500 fad74a941c0f3f9dac3bf917683c80e5 187 Gene3D G3DSA:1.25.40.960 130 187 4.9E-13 T 14-10-2018 TSH58p_12500 fad74a941c0f3f9dac3bf917683c80e5 187 SMART SM00248 128 157 0.015 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 TSH58p_12500 fad74a941c0f3f9dac3bf917683c80e5 187 SMART SM00248 95 124 3.0E-4 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 TSH58p_12500 fad74a941c0f3f9dac3bf917683c80e5 187 SMART SM00248 62 91 0.0023 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 TSH58p_12500 fad74a941c0f3f9dac3bf917683c80e5 187 SUPERFAMILY SSF48403 35 186 5.89E-39 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily TSH58p_12500 fad74a941c0f3f9dac3bf917683c80e5 187 Gene3D G3DSA:1.25.40.20 22 129 1.0E-30 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily TSH58p_12500 fad74a941c0f3f9dac3bf917683c80e5 187 Pfam PF13606 Ankyrin repeat 129 153 0.0011 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 TSH58p_12000 bec620ffbf85a03d5dec53b68437ff45 228 Gene3D G3DSA:1.10.10.1320 1 108 1.4E-32 T 14-10-2018 TSH58p_12000 bec620ffbf85a03d5dec53b68437ff45 228 TIGRFAM TIGR02451 anti_sig_ChrR: anti-sigma factor, putative, ChrR family 6 227 7.2E-57 T 14-10-2018 IPR012807 Anti-sigma factor ChrR, putative TSH58p_12000 bec620ffbf85a03d5dec53b68437ff45 228 SUPERFAMILY SSF51182 140 219 3.37E-14 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_12000 bec620ffbf85a03d5dec53b68437ff45 228 Pfam PF12973 ChrR Cupin-like domain 142 205 1.5E-11 T 14-10-2018 IPR025979 ChrR-like cupin domain TSH58p_12000 bec620ffbf85a03d5dec53b68437ff45 228 Gene3D G3DSA:2.60.120.10 110 210 2.1E-23 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_02325 6324808d7bf059cd1ea9c82dde223151 564 SUPERFAMILY SSF52540 43 503 3.61E-9 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_03070 dbfa8aab08ab28486c427831d57f4b07 346 Pfam PF01380 SIS domain 204 283 6.9E-15 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TSH58p_03070 dbfa8aab08ab28486c427831d57f4b07 346 Pfam PF01380 SIS domain 46 162 3.3E-13 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TSH58p_03070 dbfa8aab08ab28486c427831d57f4b07 346 SUPERFAMILY SSF53697 9 344 1.21E-63 T 14-10-2018 TSH58p_03070 dbfa8aab08ab28486c427831d57f4b07 346 Gene3D G3DSA:3.40.50.10490 197 331 2.6E-39 T 14-10-2018 TSH58p_03070 dbfa8aab08ab28486c427831d57f4b07 346 Gene3D G3DSA:3.40.50.10490 4 191 9.9E-42 T 14-10-2018 TSH58p_11825 3a816d045d042ef3d3ad782b65f3d788 820 SMART SM00490 171 260 6.7E-10 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_11825 3a816d045d042ef3d3ad782b65f3d788 820 Gene3D G3DSA:3.40.50.300 1 137 1.6E-25 T 14-10-2018 TSH58p_11825 3a816d045d042ef3d3ad782b65f3d788 820 Gene3D G3DSA:3.40.50.300 141 294 3.0E-31 T 14-10-2018 TSH58p_11825 3a816d045d042ef3d3ad782b65f3d788 820 SUPERFAMILY SSF52540 134 386 7.98E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_11825 3a816d045d042ef3d3ad782b65f3d788 820 Pfam PF00271 Helicase conserved C-terminal domain 160 259 8.5E-7 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_11825 3a816d045d042ef3d3ad782b65f3d788 820 SUPERFAMILY SSF52540 3 107 3.09E-7 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_09110 daee62ddc86f4f2ee3f08206e0d0a242 114 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 41 52 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_09110 daee62ddc86f4f2ee3f08206e0d0a242 114 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 10 21 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_09110 daee62ddc86f4f2ee3f08206e0d0a242 114 Pfam PF13187 4Fe-4S dicluster domain 9 55 1.5E-8 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_09110 daee62ddc86f4f2ee3f08206e0d0a242 114 SUPERFAMILY SSF54862 3 61 4.19E-18 T 14-10-2018 TSH58p_09110 daee62ddc86f4f2ee3f08206e0d0a242 114 Gene3D G3DSA:3.30.70.20 3 78 2.5E-12 T 14-10-2018 TSH58p_08105 847293179b94ebf882d7a25fe6cfb7d3 124 Pfam PF05239 PRC-barrel domain 28 84 5.1E-10 T 14-10-2018 IPR027275 PRC-barrel domain TSH58p_08105 847293179b94ebf882d7a25fe6cfb7d3 124 Gene3D G3DSA:2.30.30.240 12 100 2.9E-16 T 14-10-2018 TSH58p_08105 847293179b94ebf882d7a25fe6cfb7d3 124 SUPERFAMILY SSF50346 19 110 7.26E-13 T 14-10-2018 IPR011033 PRC-barrel-like superfamily TSH58p_20920 0efc24ece66ef385974c4bd69df9c8c3 165 Pfam PF01575 MaoC like domain 23 132 3.2E-24 T 14-10-2018 IPR002539 MaoC-like dehydratase domain TSH58p_20920 0efc24ece66ef385974c4bd69df9c8c3 165 SUPERFAMILY SSF54637 14 161 1.29E-45 T 14-10-2018 IPR029069 HotDog domain superfamily TSH58p_20920 0efc24ece66ef385974c4bd69df9c8c3 165 Gene3D G3DSA:3.10.129.10 8 160 1.5E-49 T 14-10-2018 TSH58p_00945 e14b2fa068ef6e79be9c35a5d9142593 300 Pfam PF08893 Domain of unknown function (DUF1839) 2 295 2.7E-124 T 14-10-2018 IPR014989 Protein of unknown function DUF1839 TSH58p_14340 a67d6153847d12e17ee32c178ded6791 361 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 39 361 4.2E-131 T 14-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_14340 a67d6153847d12e17ee32c178ded6791 361 ProSitePatterns PS01348 MraY family signature 2. 190 201 - T 14-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_14340 a67d6153847d12e17ee32c178ded6791 361 ProSitePatterns PS01347 MraY family signature 1. 69 81 - T 14-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_14340 a67d6153847d12e17ee32c178ded6791 361 Pfam PF00953 Glycosyl transferase family 4 100 285 6.2E-33 T 14-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 TSH58p_14340 a67d6153847d12e17ee32c178ded6791 361 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 359 24.851 T 14-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_14340 a67d6153847d12e17ee32c178ded6791 361 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 69 81 4.9E-5 T 14-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_17765 1a638507eb6b5a58990089aad73edb11 245 Pfam PF00589 Phage integrase family 72 222 9.0E-15 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TSH58p_17765 1a638507eb6b5a58990089aad73edb11 245 Gene3D G3DSA:1.10.443.10 73 223 1.7E-27 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TSH58p_17765 1a638507eb6b5a58990089aad73edb11 245 SUPERFAMILY SSF56349 1 222 2.44E-27 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TSH58p_12615 845ba23139ef306f3dc929a4f0abc4bd 154 Pfam PF09912 Uncharacterized protein conserved in bacteria (DUF2141) 37 142 9.5E-31 T 14-10-2018 IPR018673 Protein of unknown function DUF2141 TSH58p_16990 8cfc8507f4e1f13d219fc289460f2f46 110 Gene3D G3DSA:3.40.30.10 9 108 7.5E-30 T 14-10-2018 TSH58p_16990 8cfc8507f4e1f13d219fc289460f2f46 110 SUPERFAMILY SSF52833 9 106 2.57E-28 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_05035 aaf5d2f52916535769edb03cd4906a36 220 SUPERFAMILY SSF52172 1 121 3.7E-11 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_05035 aaf5d2f52916535769edb03cd4906a36 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 7.7E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_05035 aaf5d2f52916535769edb03cd4906a36 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 7.7E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_05035 aaf5d2f52916535769edb03cd4906a36 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 7.7E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_05035 aaf5d2f52916535769edb03cd4906a36 220 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_05035 aaf5d2f52916535769edb03cd4906a36 220 Gene3D G3DSA:3.40.50.12740 5 215 2.3E-40 T 14-10-2018 TSH58p_05035 aaf5d2f52916535769edb03cd4906a36 220 SMART SM00448 4 116 0.0058 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_05035 aaf5d2f52916535769edb03cd4906a36 220 SMART SM00421 152 209 1.6E-24 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_05035 aaf5d2f52916535769edb03cd4906a36 220 SUPERFAMILY SSF46894 143 215 5.1E-22 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_05035 aaf5d2f52916535769edb03cd4906a36 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 5.8E-22 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_03255 9924062ee2677633ee705a7a32710903 187 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 1 184 22.908 T 14-10-2018 IPR022929 Putative manganese efflux pump MntP TSH58p_03255 9924062ee2677633ee705a7a32710903 187 Pfam PF02659 Putative manganese efflux pump 33 181 3.5E-44 T 14-10-2018 IPR003810 Putative manganese efflux pump TSH58p_25050 414a952308fdb87089e9d59d556c3278 178 Pfam PF00994 Probable molybdopterin binding domain 16 157 8.5E-38 T 14-10-2018 IPR001453 MoaB/Mog domain TSH58p_25050 414a952308fdb87089e9d59d556c3278 178 SUPERFAMILY SSF53218 7 171 1.44E-48 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSH58p_25050 414a952308fdb87089e9d59d556c3278 178 Gene3D G3DSA:3.40.980.10 4 173 9.2E-52 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSH58p_25050 414a952308fdb87089e9d59d556c3278 178 PIRSF PIRSF006443 1 168 6.5E-64 T 14-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 TSH58p_25050 414a952308fdb87089e9d59d556c3278 178 SMART SM00852 16 160 4.8E-37 T 14-10-2018 IPR001453 MoaB/Mog domain TSH58p_25050 414a952308fdb87089e9d59d556c3278 178 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 14 152 6.2E-40 T 14-10-2018 IPR001453 MoaB/Mog domain TSH58p_25050 414a952308fdb87089e9d59d556c3278 178 TIGRFAM TIGR02667 moaB_proteo: molybdenum cofactor biosynthesis protein B 10 171 7.1E-81 T 14-10-2018 IPR013484 Molybdenum cofactor biosynthesis protein B, proteobacteria GO:0006777 TSH58p_25050 414a952308fdb87089e9d59d556c3278 178 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 74 87 - T 14-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 TSH58p_23480 9c34003c43d7aa46ee32505519beca40 218 Pfam PF12973 ChrR Cupin-like domain 111 195 3.3E-12 T 14-10-2018 IPR025979 ChrR-like cupin domain TSH58p_23480 9c34003c43d7aa46ee32505519beca40 218 TIGRFAM TIGR02451 anti_sig_ChrR: anti-sigma factor, putative, ChrR family 6 214 6.4E-44 T 14-10-2018 IPR012807 Anti-sigma factor ChrR, putative TSH58p_23480 9c34003c43d7aa46ee32505519beca40 218 SUPERFAMILY SSF51182 104 209 1.78E-19 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_23480 9c34003c43d7aa46ee32505519beca40 218 Gene3D G3DSA:1.10.10.1320 2 104 3.5E-28 T 14-10-2018 TSH58p_23480 9c34003c43d7aa46ee32505519beca40 218 Gene3D G3DSA:2.60.120.10 107 200 2.1E-24 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_26550 0964b93db390950cb970a91796373ec1 135 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 18 105 1.9E-28 T 14-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TSH58p_26550 0964b93db390950cb970a91796373ec1 135 Pfam PF03334 Na+/H+ antiporter subunit 18 98 1.6E-21 T 14-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TSH58p_16065 11251978b5f68bbfd0f6051fc7f11c07 498 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 12 484 3.1E-72 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSH58p_16065 11251978b5f68bbfd0f6051fc7f11c07 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 147 167 9.5E-46 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSH58p_16065 11251978b5f68bbfd0f6051fc7f11c07 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 264 283 9.5E-46 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSH58p_16065 11251978b5f68bbfd0f6051fc7f11c07 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 378 395 9.5E-46 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSH58p_16065 11251978b5f68bbfd0f6051fc7f11c07 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 244 263 9.5E-46 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSH58p_16065 11251978b5f68bbfd0f6051fc7f11c07 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 291 307 9.5E-46 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSH58p_16065 11251978b5f68bbfd0f6051fc7f11c07 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 332 351 9.5E-46 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSH58p_16065 11251978b5f68bbfd0f6051fc7f11c07 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 446 464 9.5E-46 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSH58p_16065 11251978b5f68bbfd0f6051fc7f11c07 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 401 422 9.5E-46 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSH58p_16065 11251978b5f68bbfd0f6051fc7f11c07 498 SUPERFAMILY SSF55486 4 496 7.33E-110 T 14-10-2018 TSH58p_16065 11251978b5f68bbfd0f6051fc7f11c07 498 PIRSF PIRSF006615 1 498 4.8E-164 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSH58p_16065 11251978b5f68bbfd0f6051fc7f11c07 498 Gene3D G3DSA:1.10.1370.30 1 497 2.4E-182 T 14-10-2018 TSH58p_27875 1109dd3dea9a8acc40e140bc2c8f2e04 387 SUPERFAMILY SSF53383 6 384 2.69E-97 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_27875 1109dd3dea9a8acc40e140bc2c8f2e04 387 Gene3D G3DSA:3.90.1150.10 14 374 2.3E-132 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_27875 1109dd3dea9a8acc40e140bc2c8f2e04 387 Pfam PF00155 Aminotransferase class I and II 28 380 1.7E-57 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSH58p_27875 1109dd3dea9a8acc40e140bc2c8f2e04 387 Gene3D G3DSA:3.40.640.10 42 279 2.3E-132 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_24265 d03040ec6af88666e1b6d0204990babc 292 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 184 209 - T 14-10-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 TSH58p_24265 d03040ec6af88666e1b6d0204990babc 292 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 188 283 1.1E-31 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 TSH58p_24265 d03040ec6af88666e1b6d0204990babc 292 Gene3D G3DSA:1.10.1040.50 191 292 3.0E-33 T 14-10-2018 TSH58p_24265 d03040ec6af88666e1b6d0204990babc 292 Gene3D G3DSA:3.40.50.720 2 190 1.1E-66 T 14-10-2018 TSH58p_24265 d03040ec6af88666e1b6d0204990babc 292 SUPERFAMILY SSF51735 1 186 7.01E-58 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_24265 d03040ec6af88666e1b6d0204990babc 292 SUPERFAMILY SSF48179 186 287 4.93E-33 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_24265 d03040ec6af88666e1b6d0204990babc 292 PIRSF PIRSF000105 1 291 4.7E-83 T 14-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 TSH58p_24265 d03040ec6af88666e1b6d0204990babc 292 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 6 184 1.4E-62 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 TSH58p_04325 342a1b857c2145d1a50cd22c3490fa7d 361 Gene3D G3DSA:3.90.1150.10 12 352 4.8E-97 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_04325 342a1b857c2145d1a50cd22c3490fa7d 361 Pfam PF00155 Aminotransferase class I and II 50 355 1.9E-40 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSH58p_04325 342a1b857c2145d1a50cd22c3490fa7d 361 SUPERFAMILY SSF53383 6 360 1.5E-77 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_04325 342a1b857c2145d1a50cd22c3490fa7d 361 Gene3D G3DSA:3.40.640.10 40 264 4.8E-97 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_04325 342a1b857c2145d1a50cd22c3490fa7d 361 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 5 360 48.446 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 TSH58p_02495 0b33cfb329eef820752191e1fff21008 551 Gene3D G3DSA:2.40.160.50 171 551 3.6E-73 T 14-10-2018 TSH58p_02495 0b33cfb329eef820752191e1fff21008 551 Pfam PF08479 POTRA domain, ShlB-type 63 137 3.6E-20 T 14-10-2018 IPR013686 Polypeptide-transport-associated, ShlB-type TSH58p_02495 0b33cfb329eef820752191e1fff21008 551 Gene3D G3DSA:3.10.20.310 50 137 6.1E-18 T 14-10-2018 TSH58p_02495 0b33cfb329eef820752191e1fff21008 551 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 200 512 1.5E-22 T 14-10-2018 IPR005565 Haemolysin activator HlyB, C-terminal TSH58p_21905 c52eb51f204fdff81b29184ad9e8ae72 495 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 18 486 2.3E-192 T 14-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 TSH58p_21905 c52eb51f204fdff81b29184ad9e8ae72 495 SUPERFAMILY SSF101960 39 492 3.01E-137 T 14-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily TSH58p_21905 c52eb51f204fdff81b29184ad9e8ae72 495 Pfam PF01458 Uncharacterized protein family (UPF0051) 233 466 6.8E-69 T 14-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 TSH58p_15205 37fb5a5d2b90c8edd7840cf5485c37d9 68 Pfam PF00831 Ribosomal L29 protein 5 60 4.6E-26 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15205 37fb5a5d2b90c8edd7840cf5485c37d9 68 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 18.486 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15205 37fb5a5d2b90c8edd7840cf5485c37d9 68 Gene3D G3DSA:1.10.287.310 1 62 5.2E-28 T 14-10-2018 TSH58p_15205 37fb5a5d2b90c8edd7840cf5485c37d9 68 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 3.1E-24 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15205 37fb5a5d2b90c8edd7840cf5485c37d9 68 SUPERFAMILY SSF46561 1 63 2.49E-23 T 14-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_10340 d2d8ba548ac9538194d671fb53bdd04e 406 Pfam PF06850 PHB de-polymerase C-terminus 204 405 1.8E-93 T 14-10-2018 IPR009656 PHB de-polymerase, C-terminal TSH58p_10340 d2d8ba548ac9538194d671fb53bdd04e 406 TIGRFAM TIGR01849 PHB_depoly_PhaZ: polyhydroxyalkanoate depolymerase, intracellular 2 405 6.4E-181 T 14-10-2018 IPR010915 Polyhydroxyalkanoate depolymerase TSH58p_10340 d2d8ba548ac9538194d671fb53bdd04e 406 PIRSF PIRSF020818 1 406 2.4E-191 T 14-10-2018 IPR010915 Polyhydroxyalkanoate depolymerase TSH58p_10340 d2d8ba548ac9538194d671fb53bdd04e 406 SUPERFAMILY SSF53474 91 403 6.67E-32 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_19970 b530d2c298a30dc4db95bc0cb17cef6b 570 SUPERFAMILY SSF161098 19 281 7.59E-51 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_19970 b530d2c298a30dc4db95bc0cb17cef6b 570 Gene3D G3DSA:1.10.3720.10 18 285 6.0E-61 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_19970 b530d2c298a30dc4db95bc0cb17cef6b 570 Gene3D G3DSA:1.10.3720.10 301 566 5.8E-42 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_19970 b530d2c298a30dc4db95bc0cb17cef6b 570 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 373 564 1.7E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_19970 b530d2c298a30dc4db95bc0cb17cef6b 570 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 273 1.2E-12 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_19970 b530d2c298a30dc4db95bc0cb17cef6b 570 SUPERFAMILY SSF161098 303 565 5.63E-45 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_22915 9e7c104eaed3703e9012f08dae274ac9 300 ProSitePatterns PS00161 Isocitrate lyase signature. 118 123 - T 14-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 TSH58p_22915 9e7c104eaed3703e9012f08dae274ac9 300 Gene3D G3DSA:3.20.20.60 3 292 5.3E-98 T 14-10-2018 TSH58p_22915 9e7c104eaed3703e9012f08dae274ac9 300 Pfam PF13714 Phosphoenolpyruvate phosphomutase 10 250 3.0E-49 T 14-10-2018 TSH58p_22915 9e7c104eaed3703e9012f08dae274ac9 300 SUPERFAMILY SSF51621 6 291 2.92E-88 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSH58p_09120 a5db875fa210a90f61a1ffdf3dc1a1f9 418 Pfam PF07690 Major Facilitator Superfamily 230 401 9.7E-14 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_09120 a5db875fa210a90f61a1ffdf3dc1a1f9 418 Pfam PF07690 Major Facilitator Superfamily 28 223 2.3E-34 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_09120 a5db875fa210a90f61a1ffdf3dc1a1f9 418 PRINTS PR01036 Tetracycline resistance protein TetB signature 147 171 1.7E-6 T 14-10-2018 TSH58p_09120 a5db875fa210a90f61a1ffdf3dc1a1f9 418 PRINTS PR01036 Tetracycline resistance protein TetB signature 117 137 1.7E-6 T 14-10-2018 TSH58p_09120 a5db875fa210a90f61a1ffdf3dc1a1f9 418 SUPERFAMILY SSF103473 20 401 1.31E-66 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_09120 a5db875fa210a90f61a1ffdf3dc1a1f9 418 Gene3D G3DSA:1.20.1250.20 16 252 6.3E-49 T 14-10-2018 TSH58p_09120 a5db875fa210a90f61a1ffdf3dc1a1f9 418 Gene3D G3DSA:1.20.1250.20 253 409 2.4E-8 T 14-10-2018 TSH58p_09120 a5db875fa210a90f61a1ffdf3dc1a1f9 418 ProSitePatterns PS00216 Sugar transport proteins signature 1. 77 93 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TSH58p_02150 2ee1ee7c78bdeff18556c66bd3890d61 327 Gene3D G3DSA:3.40.190.170 22 327 1.6E-92 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily TSH58p_02150 2ee1ee7c78bdeff18556c66bd3890d61 327 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 34 312 1.0E-71 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 TSH58p_02150 2ee1ee7c78bdeff18556c66bd3890d61 327 PIRSF PIRSF006470 2 327 4.0E-70 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 TSH58p_00660 c0c498e2d9fff17798922d1bb0a57e70 212 Pfam PF04509 CheC-like family 14 48 1.6E-8 T 14-10-2018 IPR007597 CheC-like protein GO:0016787 TSH58p_00660 c0c498e2d9fff17798922d1bb0a57e70 212 SUPERFAMILY SSF103039 9 204 1.05E-34 T 14-10-2018 IPR028976 CheC-like superfamily TSH58p_00660 c0c498e2d9fff17798922d1bb0a57e70 212 Gene3D G3DSA:3.40.1550.10 8 205 9.9E-42 T 14-10-2018 IPR028976 CheC-like superfamily TSH58p_17185 c5aae0f144e6c464cc052183acefdae6 328 Gene3D G3DSA:3.60.15.10 3 167 3.5E-21 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_17185 c5aae0f144e6c464cc052183acefdae6 328 TIGRFAM TIGR04122 Xnuc_lig_assoc: putative exonuclease, DNA ligase-associated 2 326 1.4E-143 T 14-10-2018 IPR026360 Putative exonuclease, DNA ligase-associated TSH58p_17185 c5aae0f144e6c464cc052183acefdae6 328 SUPERFAMILY SSF56281 5 310 5.69E-59 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_17185 c5aae0f144e6c464cc052183acefdae6 328 Pfam PF12706 Beta-lactamase superfamily domain 11 132 9.8E-7 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_02240 2dd0c518c134b8ef058ec0cdc58e55e6 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 287 1.8E-26 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_02240 2dd0c518c134b8ef058ec0cdc58e55e6 293 SUPERFAMILY SSF161098 80 267 5.1E-27 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_02240 2dd0c518c134b8ef058ec0cdc58e55e6 293 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 16 62 9.9E-8 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TSH58p_02240 2dd0c518c134b8ef058ec0cdc58e55e6 293 Gene3D G3DSA:1.10.3720.10 76 282 6.1E-23 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_19830 5a38892bd52851343284294763a8bd11 309 SUPERFAMILY SSF103481 193 289 8.24E-13 T 14-10-2018 TSH58p_19830 5a38892bd52851343284294763a8bd11 309 SUPERFAMILY SSF103481 57 149 2.22E-8 T 14-10-2018 TSH58p_19830 5a38892bd52851343284294763a8bd11 309 Pfam PF00892 EamA-like transporter family 16 147 2.4E-7 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_19830 5a38892bd52851343284294763a8bd11 309 Pfam PF00892 EamA-like transporter family 156 284 5.0E-11 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_30915 45df337c4412a1a1de0823abae0a4bdb 267 SUPERFAMILY SSF52540 1 217 2.3E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_30915 45df337c4412a1a1de0823abae0a4bdb 267 Gene3D G3DSA:3.40.50.300 1 259 4.0E-61 T 14-10-2018 TSH58p_30915 45df337c4412a1a1de0823abae0a4bdb 267 Pfam PF00005 ABC transporter 22 161 6.9E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_30915 45df337c4412a1a1de0823abae0a4bdb 267 SMART SM00382 31 212 1.6E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_30915 45df337c4412a1a1de0823abae0a4bdb 267 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_08470 2747aa421be81873aaf8760056a58ae8 149 Pfam PF13463 Winged helix DNA-binding domain 39 102 1.5E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_08470 2747aa421be81873aaf8760056a58ae8 149 SMART SM00347 29 128 2.1E-17 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_08470 2747aa421be81873aaf8760056a58ae8 149 Gene3D G3DSA:1.10.10.10 3 147 1.0E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_08470 2747aa421be81873aaf8760056a58ae8 149 SUPERFAMILY SSF46785 15 145 9.67E-27 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_05660 58d7d1d624a135f3d402b18202550dd3 232 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 185 197 9.4E-9 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 TSH58p_05660 58d7d1d624a135f3d402b18202550dd3 232 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 156 167 9.4E-9 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 TSH58p_05660 58d7d1d624a135f3d402b18202550dd3 232 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 145 155 9.4E-9 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 TSH58p_05660 58d7d1d624a135f3d402b18202550dd3 232 Pfam PF01726 LexA DNA binding domain 2 63 1.0E-13 T 14-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 TSH58p_05660 58d7d1d624a135f3d402b18202550dd3 232 SUPERFAMILY SSF46785 2 68 1.8E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_05660 58d7d1d624a135f3d402b18202550dd3 232 TIGRFAM TIGR00498 lexA: repressor LexA 2 231 1.1E-49 T 14-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 TSH58p_05660 58d7d1d624a135f3d402b18202550dd3 232 Hamap MF_00015 LexA repressor [lexA]. 1 232 32.505 T 14-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 TSH58p_05660 58d7d1d624a135f3d402b18202550dd3 232 Gene3D G3DSA:2.10.109.10 114 232 4.6E-35 T 14-10-2018 TSH58p_05660 58d7d1d624a135f3d402b18202550dd3 232 Gene3D G3DSA:1.10.10.10 1 68 5.2E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_05660 58d7d1d624a135f3d402b18202550dd3 232 Pfam PF00717 Peptidase S24-like 148 211 1.5E-10 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C TSH58p_05660 58d7d1d624a135f3d402b18202550dd3 232 SUPERFAMILY SSF51306 108 230 6.28E-30 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily TSH58p_11675 f8f1c411f9a7ec5d8c58bf5f3c3d1e53 347 Gene3D G3DSA:3.40.190.10 32 311 4.7E-54 T 14-10-2018 TSH58p_11675 f8f1c411f9a7ec5d8c58bf5f3c3d1e53 347 Gene3D G3DSA:3.40.190.10 116 284 4.7E-54 T 14-10-2018 TSH58p_11675 f8f1c411f9a7ec5d8c58bf5f3c3d1e53 347 Pfam PF12849 PBP superfamily domain 22 310 2.2E-42 T 14-10-2018 IPR024370 PBP domain TSH58p_11675 f8f1c411f9a7ec5d8c58bf5f3c3d1e53 347 SUPERFAMILY SSF53850 30 339 1.19E-67 T 14-10-2018 TSH58p_12170 40e624453990b9a0451df20aea4c13f6 275 SUPERFAMILY SSF54675 3 105 4.24E-21 T 14-10-2018 TSH58p_12170 40e624453990b9a0451df20aea4c13f6 275 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 17 104 2.2E-18 T 14-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 TSH58p_12170 40e624453990b9a0451df20aea4c13f6 275 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 106 257 8.5E-27 T 14-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 TSH58p_12170 40e624453990b9a0451df20aea4c13f6 275 Gene3D G3DSA:3.90.1170.20 10 118 1.4E-59 T 14-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 TSH58p_12170 40e624453990b9a0451df20aea4c13f6 275 TIGRFAM TIGR01334 modD: modD protein 2 272 2.4E-79 T 14-10-2018 IPR006242 Putative pyrophosphorylase ModD GO:0016763 TSH58p_12170 40e624453990b9a0451df20aea4c13f6 275 SUPERFAMILY SSF51690 106 269 8.63E-40 T 14-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 TSH58p_12170 40e624453990b9a0451df20aea4c13f6 275 PIRSF PIRSF006250 1 274 2.9E-56 T 14-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 TSH58p_12170 40e624453990b9a0451df20aea4c13f6 275 Gene3D G3DSA:3.20.20.70 119 259 1.4E-59 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_29555 27ccdbcc92ca33d3570f283eb026c497 129 SUPERFAMILY SSF47226 13 124 3.53E-14 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_29555 27ccdbcc92ca33d3570f283eb026c497 129 Pfam PF01627 Hpt domain 43 122 7.9E-7 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TSH58p_29555 27ccdbcc92ca33d3570f283eb026c497 129 Gene3D G3DSA:1.20.120.160 19 127 1.1E-12 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 TSH58p_29300 811e206b8a70c388aff0a09d6708458b 288 SUPERFAMILY SSF55021 8 92 2.75E-16 T 14-10-2018 TSH58p_29300 811e206b8a70c388aff0a09d6708458b 288 Pfam PF00551 Formyl transferase 93 269 3.3E-37 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TSH58p_29300 811e206b8a70c388aff0a09d6708458b 288 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 9 287 4.7E-105 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TSH58p_29300 811e206b8a70c388aff0a09d6708458b 288 PIRSF PIRSF036480 5 288 4.3E-115 T 14-10-2018 TSH58p_29300 811e206b8a70c388aff0a09d6708458b 288 SUPERFAMILY SSF53328 93 288 6.93E-64 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TSH58p_29300 811e206b8a70c388aff0a09d6708458b 288 Gene3D G3DSA:3.40.50.170 92 287 1.5E-72 T 14-10-2018 TSH58p_29300 811e206b8a70c388aff0a09d6708458b 288 Gene3D G3DSA:3.30.70.260 2 91 1.6E-28 T 14-10-2018 TSH58p_29300 811e206b8a70c388aff0a09d6708458b 288 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 5 287 48.55 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TSH58p_29300 811e206b8a70c388aff0a09d6708458b 288 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 261 286 2.9E-52 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TSH58p_29300 811e206b8a70c388aff0a09d6708458b 288 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 93 115 2.9E-52 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TSH58p_29300 811e206b8a70c388aff0a09d6708458b 288 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 115 142 2.9E-52 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TSH58p_29300 811e206b8a70c388aff0a09d6708458b 288 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 239 261 2.9E-52 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TSH58p_29300 811e206b8a70c388aff0a09d6708458b 288 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 10 36 2.9E-52 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TSH58p_29300 811e206b8a70c388aff0a09d6708458b 288 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 42 54 2.9E-52 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TSH58p_11655 6788dc423638ebf141b8743bb58b2c30 61 TIGRFAM TIGR00847 ccoS: cytochrome oxidase maturation protein, cbb3-type 1 47 3.3E-23 T 14-10-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type TSH58p_11655 6788dc423638ebf141b8743bb58b2c30 61 Pfam PF03597 Cytochrome oxidase maturation protein cbb3-type 4 45 1.3E-21 T 14-10-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type TSH58p_13775 5355543e52f38e57dafd894d6831e36c 261 SUPERFAMILY SSF52540 13 255 1.33E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_13775 5355543e52f38e57dafd894d6831e36c 261 SMART SM00382 39 233 2.9E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_13775 5355543e52f38e57dafd894d6831e36c 261 Gene3D G3DSA:3.40.50.300 14 260 1.8E-60 T 14-10-2018 TSH58p_13775 5355543e52f38e57dafd894d6831e36c 261 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 235 255 2.4E-11 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSH58p_13775 5355543e52f38e57dafd894d6831e36c 261 Pfam PF00005 ABC transporter 31 186 5.0E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_22260 ca736b8f3289c8240a8e4d5094546ade 90 Pfam PF11666 Protein of unknown function (DUF2933) 30 78 1.3E-17 T 14-10-2018 IPR021682 Protein of unknown function DUF2933 TSH58p_01175 bf3c131a995b2c93871cc5034fdf3d61 554 TIGRFAM TIGR03121 one_C_dehyd_A: formylmethanofuran dehydrogenase subunit A 3 539 1.6E-208 T 14-10-2018 IPR012027 Formylmethanofuran dehydrogenase, subunit A TSH58p_01175 bf3c131a995b2c93871cc5034fdf3d61 554 SUPERFAMILY SSF51556 59 451 3.74E-29 T 14-10-2018 IPR032466 Metal-dependent hydrolase TSH58p_01175 bf3c131a995b2c93871cc5034fdf3d61 554 SUPERFAMILY SSF51338 5 67 6.28E-10 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_01175 bf3c131a995b2c93871cc5034fdf3d61 554 Pfam PF07969 Amidohydrolase family 47 494 1.1E-57 T 14-10-2018 IPR013108 Amidohydrolase 3 TSH58p_01175 bf3c131a995b2c93871cc5034fdf3d61 554 SUPERFAMILY SSF51338 425 509 2.25E-19 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_01175 bf3c131a995b2c93871cc5034fdf3d61 554 PIRSF PIRSF006453 1 547 4.3E-220 T 14-10-2018 IPR012027 Formylmethanofuran dehydrogenase, subunit A TSH58p_01175 bf3c131a995b2c93871cc5034fdf3d61 554 Gene3D G3DSA:2.30.40.10 3 87 2.6E-7 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_19875 3c5d8ef2bd35c598ddd0b88780fe4e4d 57 PIRSF PIRSF036466 1 55 1.0E-18 T 14-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 TSH58p_19875 3c5d8ef2bd35c598ddd0b88780fe4e4d 57 Pfam PF07043 Protein of unknown function (DUF1328) 6 44 2.1E-13 T 14-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 TSH58p_19875 3c5d8ef2bd35c598ddd0b88780fe4e4d 57 Hamap MF_01361 UPF0391 membrane protein YtjA [ytjA]. 1 56 18.103 T 14-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 TSH58p_29845 c6808351b44699dadc862b11e74fad1c 234 SUPERFAMILY SSF53474 4 231 1.99E-48 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_29845 c6808351b44699dadc862b11e74fad1c 234 Pfam PF12697 Alpha/beta hydrolase family 7 225 5.3E-14 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_29845 c6808351b44699dadc862b11e74fad1c 234 Gene3D G3DSA:3.40.50.1820 2 232 6.1E-47 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_29845 c6808351b44699dadc862b11e74fad1c 234 PRINTS PR00111 Alpha/beta hydrolase fold signature 61 74 2.0E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_29845 c6808351b44699dadc862b11e74fad1c 234 PRINTS PR00111 Alpha/beta hydrolase fold signature 177 191 2.0E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_29845 c6808351b44699dadc862b11e74fad1c 234 PRINTS PR00111 Alpha/beta hydrolase fold signature 75 88 2.0E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_22510 5f3ac1a2e98163ca46bb405684f314e8 400 Pfam PF13286 Phosphohydrolase-associated domain 298 392 2.1E-26 T 14-10-2018 IPR026875 Phosphohydrolase-associated domain TSH58p_22510 5f3ac1a2e98163ca46bb405684f314e8 400 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 10 394 39.172 T 14-10-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 TSH58p_22510 5f3ac1a2e98163ca46bb405684f314e8 400 SMART SM00471 66 221 8.6E-11 T 14-10-2018 IPR003607 HD/PDEase domain TSH58p_22510 5f3ac1a2e98163ca46bb405684f314e8 400 Pfam PF01966 HD domain 70 211 1.1E-15 T 14-10-2018 IPR006674 HD domain TSH58p_22510 5f3ac1a2e98163ca46bb405684f314e8 400 SUPERFAMILY SSF109604 21 395 1.08E-91 T 14-10-2018 TSH58p_22510 5f3ac1a2e98163ca46bb405684f314e8 400 Gene3D G3DSA:1.10.3210.10 2 395 8.9E-130 T 14-10-2018 TSH58p_22510 5f3ac1a2e98163ca46bb405684f314e8 400 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 32 394 2.2E-98 T 14-10-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 TSH58p_20555 42cdbc0ebbc83f52a7a817cacfa4d400 429 Pfam PF07969 Amidohydrolase family 40 400 6.5E-48 T 14-10-2018 IPR013108 Amidohydrolase 3 TSH58p_20555 42cdbc0ebbc83f52a7a817cacfa4d400 429 Gene3D G3DSA:3.20.20.140 53 360 3.0E-157 T 14-10-2018 TSH58p_20555 42cdbc0ebbc83f52a7a817cacfa4d400 429 SUPERFAMILY SSF51556 52 371 1.18E-104 T 14-10-2018 IPR032466 Metal-dependent hydrolase TSH58p_20555 42cdbc0ebbc83f52a7a817cacfa4d400 429 SUPERFAMILY SSF51338 1 380 4.49E-16 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_20555 42cdbc0ebbc83f52a7a817cacfa4d400 429 Gene3D G3DSA:2.30.40.10 9 403 3.0E-157 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_21525 392e2044e45d939ae6472038b840d788 287 Gene3D G3DSA:3.20.10.10 121 283 3.4E-55 T 14-10-2018 TSH58p_21525 392e2044e45d939ae6472038b840d788 287 Gene3D G3DSA:3.30.470.10 1 118 7.1E-31 T 14-10-2018 TSH58p_21525 392e2044e45d939ae6472038b840d788 287 Pfam PF01063 Amino-transferase class IV 31 256 3.3E-45 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 TSH58p_21525 392e2044e45d939ae6472038b840d788 287 SUPERFAMILY SSF56752 3 285 8.76E-80 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 TSH58p_23255 f0a19f4cc7e856e70bc6f5ad7b4d8536 222 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 8 216 4.8E-74 T 14-10-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 TSH58p_23255 f0a19f4cc7e856e70bc6f5ad7b4d8536 222 SUPERFAMILY SSF161098 3 213 6.02E-46 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_23255 f0a19f4cc7e856e70bc6f5ad7b4d8536 222 Gene3D G3DSA:1.10.3720.10 1 218 4.8E-53 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_23255 f0a19f4cc7e856e70bc6f5ad7b4d8536 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 24 209 1.9E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_15490 ae8626589eed510c62eb573b905c71b3 136 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 5 135 2.2E-45 T 14-10-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 TSH58p_15490 ae8626589eed510c62eb573b905c71b3 136 Pfam PF00460 Flagella basal body rod protein 9 34 3.0E-7 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 TSH58p_15490 ae8626589eed510c62eb573b905c71b3 136 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 14-10-2018 IPR019776 Flagellar basal body rod protein, conserved site TSH58p_15490 ae8626589eed510c62eb573b905c71b3 136 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 89 132 1.9E-9 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain TSH58p_02160 2826988906292822c18003c4330c035f 425 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 15 421 4.6E-117 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSH58p_02160 2826988906292822c18003c4330c035f 425 PIRSF PIRSF006066 1 425 3.8E-119 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSH58p_02160 2826988906292822c18003c4330c035f 425 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 6 415 5.3E-98 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TSH58p_13605 b2d1a5c447e5407194e3e868b14c3abc 293 SUPERFAMILY SSF53474 2 292 2.27E-75 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_13605 b2d1a5c447e5407194e3e868b14c3abc 293 Gene3D G3DSA:3.40.50.1820 1 292 4.3E-86 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_13605 b2d1a5c447e5407194e3e868b14c3abc 293 Pfam PF00561 alpha/beta hydrolase fold 26 246 9.7E-24 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_13605 b2d1a5c447e5407194e3e868b14c3abc 293 PRINTS PR00412 Epoxide hydrolase signature 268 290 1.2E-8 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TSH58p_13605 b2d1a5c447e5407194e3e868b14c3abc 293 PRINTS PR00412 Epoxide hydrolase signature 114 127 1.2E-8 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TSH58p_13605 b2d1a5c447e5407194e3e868b14c3abc 293 PRINTS PR00412 Epoxide hydrolase signature 100 113 1.2E-8 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TSH58p_13605 b2d1a5c447e5407194e3e868b14c3abc 293 PRINTS PR00412 Epoxide hydrolase signature 32 50 1.2E-8 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TSH58p_00020 7352c07c30468e9845f3574454b818df 324 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 30 47 2.4E-12 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TSH58p_00020 7352c07c30468e9845f3574454b818df 324 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 109 130 2.4E-12 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TSH58p_00020 7352c07c30468e9845f3574454b818df 324 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 257 275 2.4E-12 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TSH58p_00020 7352c07c30468e9845f3574454b818df 324 Gene3D G3DSA:2.120.10.30 21 297 7.8E-37 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TSH58p_00020 7352c07c30468e9845f3574454b818df 324 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 30 274 2.8E-28 T 14-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region TSH58p_00020 7352c07c30468e9845f3574454b818df 324 SUPERFAMILY SSF63829 27 278 1.21E-23 T 14-10-2018 TSH58p_13350 68b226b039e6fb47a54deab2f049c4c5 206 Gene3D G3DSA:1.20.1050.10 86 195 4.2E-66 T 14-10-2018 TSH58p_13350 68b226b039e6fb47a54deab2f049c4c5 206 Pfam PF00043 Glutathione S-transferase, C-terminal domain 127 196 1.8E-13 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal TSH58p_13350 68b226b039e6fb47a54deab2f049c4c5 206 Gene3D G3DSA:3.40.30.10 2 205 4.2E-66 T 14-10-2018 TSH58p_13350 68b226b039e6fb47a54deab2f049c4c5 206 SUPERFAMILY SSF52833 1 86 6.41E-16 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_13350 68b226b039e6fb47a54deab2f049c4c5 206 SUPERFAMILY SSF47616 81 203 3.48E-32 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily TSH58p_13350 68b226b039e6fb47a54deab2f049c4c5 206 Pfam PF02798 Glutathione S-transferase, N-terminal domain 2 76 1.2E-10 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 TSH58p_08540 177a26bb1b3fb9da7bcdc826caa73784 618 SMART SM00028 65 98 28.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_08540 177a26bb1b3fb9da7bcdc826caa73784 618 SMART SM00028 31 64 4.2 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_08540 177a26bb1b3fb9da7bcdc826caa73784 618 SMART SM00028 99 132 37.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_08540 177a26bb1b3fb9da7bcdc826caa73784 618 SMART SM00028 133 166 0.0015 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_08540 177a26bb1b3fb9da7bcdc826caa73784 618 SMART SM00028 201 234 0.048 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_08540 177a26bb1b3fb9da7bcdc826caa73784 618 SMART SM00028 167 200 0.0036 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_08540 177a26bb1b3fb9da7bcdc826caa73784 618 Gene3D G3DSA:1.25.40.10 21 295 1.4E-52 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_08540 177a26bb1b3fb9da7bcdc826caa73784 618 SUPERFAMILY SSF48452 23 234 5.77E-33 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_08540 177a26bb1b3fb9da7bcdc826caa73784 618 SUPERFAMILY SSF53756 319 566 2.17E-8 T 14-10-2018 TSH58p_08540 177a26bb1b3fb9da7bcdc826caa73784 618 Pfam PF14559 Tetratricopeptide repeat 178 233 6.3E-7 T 14-10-2018 TSH58p_08540 177a26bb1b3fb9da7bcdc826caa73784 618 SUPERFAMILY SSF48452 208 286 1.52E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_08540 177a26bb1b3fb9da7bcdc826caa73784 618 Pfam PF13432 Tetratricopeptide repeat 28 63 0.0085 T 14-10-2018 TSH58p_08540 177a26bb1b3fb9da7bcdc826caa73784 618 Pfam PF13432 Tetratricopeptide repeat 70 132 0.011 T 14-10-2018 TSH58p_08000 de3b04eee1a44c3c6992d54965cc5b3e 208 Gene3D G3DSA:3.90.550.10 2 203 5.9E-47 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_08000 de3b04eee1a44c3c6992d54965cc5b3e 208 Pfam PF12804 MobA-like NTP transferase domain 8 165 1.1E-33 T 14-10-2018 IPR025877 MobA-like NTP transferase TSH58p_08000 de3b04eee1a44c3c6992d54965cc5b3e 208 TIGRFAM TIGR02665 molyb_mobA: molybdenum cofactor guanylyltransferase 6 196 4.7E-62 T 14-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 TSH58p_08000 de3b04eee1a44c3c6992d54965cc5b3e 208 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 4 198 26.757 T 14-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 TSH58p_08000 de3b04eee1a44c3c6992d54965cc5b3e 208 SUPERFAMILY SSF53448 6 195 4.69E-26 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_01570 61b4f6015dcbb2332bebbfa25a08d6f2 294 Gene3D G3DSA:1.10.260.40 16 86 6.5E-12 T 14-10-2018 TSH58p_01570 61b4f6015dcbb2332bebbfa25a08d6f2 294 SUPERFAMILY SSF47413 19 77 2.95E-13 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_01570 61b4f6015dcbb2332bebbfa25a08d6f2 294 Pfam PF13560 Helix-turn-helix domain 20 80 4.2E-10 T 14-10-2018 TSH58p_01570 61b4f6015dcbb2332bebbfa25a08d6f2 294 SMART SM00530 23 78 6.5E-8 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_20220 77dfe5172df09efc013ea9bbf14dd4ce 565 PRINTS PR01009 Flagellar M-ring protein signature 146 160 1.7E-31 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 TSH58p_20220 77dfe5172df09efc013ea9bbf14dd4ce 565 PRINTS PR01009 Flagellar M-ring protein signature 189 207 1.7E-31 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 TSH58p_20220 77dfe5172df09efc013ea9bbf14dd4ce 565 PRINTS PR01009 Flagellar M-ring protein signature 258 276 1.7E-31 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 TSH58p_20220 77dfe5172df09efc013ea9bbf14dd4ce 565 PRINTS PR01009 Flagellar M-ring protein signature 114 132 1.7E-31 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 TSH58p_20220 77dfe5172df09efc013ea9bbf14dd4ce 565 PRINTS PR01009 Flagellar M-ring protein signature 334 358 1.7E-31 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 TSH58p_20220 77dfe5172df09efc013ea9bbf14dd4ce 565 Pfam PF08345 Flagellar M-ring protein C-terminal 247 410 2.2E-39 T 14-10-2018 IPR013556 Flagellar M-ring C-terminal TSH58p_20220 77dfe5172df09efc013ea9bbf14dd4ce 565 PIRSF PIRSF004862 2 564 6.1E-129 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 TSH58p_20220 77dfe5172df09efc013ea9bbf14dd4ce 565 Gene3D G3DSA:3.30.300.30 115 214 7.5E-11 T 14-10-2018 TSH58p_20220 77dfe5172df09efc013ea9bbf14dd4ce 565 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 21 463 3.4E-81 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 TSH58p_20220 77dfe5172df09efc013ea9bbf14dd4ce 565 Pfam PF01514 Secretory protein of YscJ/FliF family 24 212 3.7E-61 T 14-10-2018 IPR006182 Secretory protein YscJ/FliF TSH58p_13155 790eafe2e52b99cace1bd85afc1715d3 198 Gene3D G3DSA:2.40.30.60 3 89 3.8E-19 T 14-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 TSH58p_13155 790eafe2e52b99cace1bd85afc1715d3 198 SUPERFAMILY SSF50346 96 163 2.88E-15 T 14-10-2018 IPR011033 PRC-barrel-like superfamily TSH58p_13155 790eafe2e52b99cace1bd85afc1715d3 198 SUPERFAMILY SSF50447 5 89 5.89E-19 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSH58p_13155 790eafe2e52b99cace1bd85afc1715d3 198 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 5 164 5.6E-40 T 14-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 TSH58p_13155 790eafe2e52b99cace1bd85afc1715d3 198 Gene3D G3DSA:2.30.30.240 92 170 1.5E-12 T 14-10-2018 TSH58p_13155 790eafe2e52b99cace1bd85afc1715d3 198 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 4 166 22.888 T 14-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 TSH58p_13155 790eafe2e52b99cace1bd85afc1715d3 198 Pfam PF05239 PRC-barrel domain 93 163 1.1E-7 T 14-10-2018 IPR027275 PRC-barrel domain TSH58p_13155 790eafe2e52b99cace1bd85afc1715d3 198 Pfam PF01782 RimM N-terminal domain 7 86 3.6E-19 T 14-10-2018 IPR002676 RimM, N-terminal GO:0006364 TSH58p_06680 3db962abbdcc5eebb47fc447880705cc 308 Gene3D G3DSA:1.20.1510.10 4 217 3.4E-14 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TSH58p_06680 3db962abbdcc5eebb47fc447880705cc 308 SUPERFAMILY SSF161111 3 215 7.59E-27 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TSH58p_06680 3db962abbdcc5eebb47fc447880705cc 308 Pfam PF01545 Cation efflux family 8 215 1.6E-32 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TSH58p_09225 fa4b0e88c904c302d341d56c8db101f7 676 SUPERFAMILY SSF51126 185 381 4.32E-24 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor TSH58p_09225 fa4b0e88c904c302d341d56c8db101f7 676 Gene3D G3DSA:2.160.20.10 156 292 1.4E-27 T 14-10-2018 IPR012334 Pectin lyase fold TSH58p_09225 fa4b0e88c904c302d341d56c8db101f7 676 Pfam PF12708 Pectate lyase superfamily protein 189 263 9.0E-18 T 14-10-2018 IPR024535 Pectate lyase superfamily protein TSH58p_23490 df4230e5c664dd0c8e11c46b30f7a66a 478 Gene3D G3DSA:3.40.50.300 142 328 6.1E-65 T 14-10-2018 TSH58p_23490 df4230e5c664dd0c8e11c46b30f7a66a 478 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 451 471 8.1E-10 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_23490 df4230e5c664dd0c8e11c46b30f7a66a 478 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 434 451 8.1E-10 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_23490 df4230e5c664dd0c8e11c46b30f7a66a 478 Pfam PF02954 Bacterial regulatory protein, Fis family 428 467 4.8E-13 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_23490 df4230e5c664dd0c8e11c46b30f7a66a 478 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 244 259 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 TSH58p_23490 df4230e5c664dd0c8e11c46b30f7a66a 478 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 371 380 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site TSH58p_23490 df4230e5c664dd0c8e11c46b30f7a66a 478 Gene3D G3DSA:1.10.10.60 413 472 8.2E-16 T 14-10-2018 TSH58p_23490 df4230e5c664dd0c8e11c46b30f7a66a 478 Pfam PF00158 Sigma-54 interaction domain 157 325 6.0E-67 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 TSH58p_23490 df4230e5c664dd0c8e11c46b30f7a66a 478 SUPERFAMILY SSF46689 371 470 1.0E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_23490 df4230e5c664dd0c8e11c46b30f7a66a 478 SMART SM00382 177 325 5.2E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_23490 df4230e5c664dd0c8e11c46b30f7a66a 478 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 181 194 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 TSH58p_23490 df4230e5c664dd0c8e11c46b30f7a66a 478 SUPERFAMILY SSF55785 21 114 9.71E-11 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_23490 df4230e5c664dd0c8e11c46b30f7a66a 478 SUPERFAMILY SSF52540 157 402 7.66E-69 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_23490 df4230e5c664dd0c8e11c46b30f7a66a 478 Pfam PF08448 PAS fold 27 115 5.0E-6 T 14-10-2018 IPR013656 PAS fold-4 TSH58p_23490 df4230e5c664dd0c8e11c46b30f7a66a 478 Gene3D G3DSA:3.30.450.20 7 115 4.7E-10 T 14-10-2018 TSH58p_23490 df4230e5c664dd0c8e11c46b30f7a66a 478 Gene3D G3DSA:1.10.8.60 329 406 1.3E-18 T 14-10-2018 TSH58p_16505 ebdc6df9cbd04db597b15bfbdee9fa12 418 Pfam PF03600 Citrate transporter 26 341 4.9E-25 T 14-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 TSH58p_25670 18ccd46bc00dd199c95471a448195b1e 410 Pfam PF07687 Peptidase dimerisation domain 192 302 1.8E-17 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain TSH58p_25670 18ccd46bc00dd199c95471a448195b1e 410 Gene3D G3DSA:3.40.630.10 31 406 4.5E-82 T 14-10-2018 TSH58p_25670 18ccd46bc00dd199c95471a448195b1e 410 SUPERFAMILY SSF53187 7 406 7.38E-57 T 14-10-2018 TSH58p_25670 18ccd46bc00dd199c95471a448195b1e 410 Gene3D G3DSA:3.30.70.360 196 315 4.5E-82 T 14-10-2018 TSH58p_25670 18ccd46bc00dd199c95471a448195b1e 410 SUPERFAMILY SSF55031 196 314 1.94E-23 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TSH58p_25670 18ccd46bc00dd199c95471a448195b1e 410 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 90 99 - T 14-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 TSH58p_25670 18ccd46bc00dd199c95471a448195b1e 410 Pfam PF01546 Peptidase family M20/M25/M40 91 402 1.7E-29 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 TSH58p_06480 7750868d7cfe97d8ce1f1e43d6f69536 625 SUPERFAMILY SSF56601 243 598 2.91E-98 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TSH58p_06480 7750868d7cfe97d8ce1f1e43d6f69536 625 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 13 599 4.9E-217 T 14-10-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0009002|GO:0009252|GO:0016020 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TSH58p_06480 7750868d7cfe97d8ce1f1e43d6f69536 625 Pfam PF03717 Penicillin-binding Protein dimerisation domain 59 228 3.6E-41 T 14-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 TSH58p_06480 7750868d7cfe97d8ce1f1e43d6f69536 625 Gene3D G3DSA:3.30.1390.30 79 154 6.1E-38 T 14-10-2018 TSH58p_06480 7750868d7cfe97d8ce1f1e43d6f69536 625 SUPERFAMILY SSF56519 50 242 1.96E-44 T 14-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 TSH58p_06480 7750868d7cfe97d8ce1f1e43d6f69536 625 Gene3D G3DSA:3.90.1310.10 59 237 6.1E-38 T 14-10-2018 TSH58p_06480 7750868d7cfe97d8ce1f1e43d6f69536 625 Pfam PF00905 Penicillin binding protein transpeptidase domain 262 597 6.6E-72 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 TSH58p_06480 7750868d7cfe97d8ce1f1e43d6f69536 625 Gene3D G3DSA:3.40.710.10 238 610 1.0E-100 T 14-10-2018 TSH58p_17835 7ed8b00567b598d5f7d8dfdd5028315b 360 PIRSF PIRSF030158 1 358 3.3E-87 T 14-10-2018 IPR024698 Capsular polysaccharide biosynthesis protein, Cps23fI-type, predicted TSH58p_17835 7ed8b00567b598d5f7d8dfdd5028315b 360 Pfam PF04577 Protein of unknown function (DUF563) 130 331 6.5E-42 T 14-10-2018 IPR007657 Glycosyltransferase 61 GO:0016757 TSH58p_16655 db0dca41636fbebca604869b2c0aad69 368 SUPERFAMILY SSF56112 30 318 2.77E-40 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily TSH58p_16655 db0dca41636fbebca604869b2c0aad69 368 Pfam PF01636 Phosphotransferase enzyme family 82 278 4.2E-30 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase TSH58p_16655 db0dca41636fbebca604869b2c0aad69 368 Gene3D G3DSA:3.90.1200.10 125 332 2.6E-38 T 14-10-2018 TSH58p_16655 db0dca41636fbebca604869b2c0aad69 368 Gene3D G3DSA:3.30.200.20 9 121 2.2E-11 T 14-10-2018 TSH58p_01890 b71e68f840c9e94ee4adbae1cb51c4fa 344 SUPERFAMILY SSF52540 72 333 1.01E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_01890 b71e68f840c9e94ee4adbae1cb51c4fa 344 Gene3D G3DSA:3.40.50.300 65 341 1.3E-63 T 14-10-2018 TSH58p_01890 b71e68f840c9e94ee4adbae1cb51c4fa 344 Gene3D G3DSA:1.10.260.40 1 60 3.6E-5 T 14-10-2018 TSH58p_01890 b71e68f840c9e94ee4adbae1cb51c4fa 344 Pfam PF13614 AAA domain 71 255 2.4E-40 T 14-10-2018 IPR025669 AAA domain TSH58p_22235 cae539da91de3888d267ca237d1ef04d 563 Gene3D G3DSA:1.20.210.10 21 556 1.3E-53 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_22235 cae539da91de3888d267ca237d1ef04d 563 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 33 480 3.3E-31 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_22235 cae539da91de3888d267ca237d1ef04d 563 SUPERFAMILY SSF81442 26 505 7.46E-33 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16390 7be474c1935d936db7e559e25e11d6de 139 Gene3D G3DSA:2.20.25.10 1 32 2.3E-17 T 14-10-2018 TSH58p_16390 7be474c1935d936db7e559e25e11d6de 139 SUPERFAMILY SSF82784 1 137 5.37E-43 T 14-10-2018 IPR036102 OsmC/Ohr superfamily TSH58p_16390 7be474c1935d936db7e559e25e11d6de 139 Gene3D G3DSA:3.30.300.20 39 136 1.3E-30 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta TSH58p_16390 7be474c1935d936db7e559e25e11d6de 139 Pfam PF02566 OsmC-like protein 34 130 3.7E-17 T 14-10-2018 IPR003718 OsmC/Ohr family TSH58p_26535 2c005060658e992e05709f479bb107fc 539 Pfam PF00361 Proton-conducting membrane transporter 132 435 2.1E-34 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_16270 47711f53e4c74e8b7e9240adf08850ec 273 SMART SM00854 2 200 0.0065 T 14-10-2018 IPR019079 Capsule synthesis protein, CapA TSH58p_16270 47711f53e4c74e8b7e9240adf08850ec 273 SUPERFAMILY SSF56300 1 260 2.86E-83 T 14-10-2018 TSH58p_16270 47711f53e4c74e8b7e9240adf08850ec 273 PIRSF PIRSF004789 1 267 1.6E-84 T 14-10-2018 IPR005235 Metallophosphoesterase, YmdB-like TSH58p_16270 47711f53e4c74e8b7e9240adf08850ec 273 Pfam PF13277 YmdB-like protein 4 259 1.8E-98 T 14-10-2018 IPR005235 Metallophosphoesterase, YmdB-like TSH58p_16270 47711f53e4c74e8b7e9240adf08850ec 273 Gene3D G3DSA:3.60.21.10 1 268 1.1E-100 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like TSH58p_07350 6b2dd31045273f5f6ee3c658b9bd66d8 548 SMART SM00857 3 145 1.0E-35 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 TSH58p_07350 6b2dd31045273f5f6ee3c658b9bd66d8 548 Gene3D G3DSA:1.10.10.2600 129 289 6.6E-12 T 14-10-2018 IPR038109 DNA-binding recombinase domain superfamily TSH58p_07350 6b2dd31045273f5f6ee3c658b9bd66d8 548 Gene3D G3DSA:3.40.50.1390 1 109 1.6E-26 T 14-10-2018 TSH58p_07350 6b2dd31045273f5f6ee3c658b9bd66d8 548 Pfam PF00239 Resolvase, N terminal domain 3 143 6.0E-23 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 TSH58p_07350 6b2dd31045273f5f6ee3c658b9bd66d8 548 SUPERFAMILY SSF53041 1 143 2.88E-27 T 14-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 TSH58p_07350 6b2dd31045273f5f6ee3c658b9bd66d8 548 Pfam PF13408 Recombinase zinc beta ribbon domain 304 358 3.1E-10 T 14-10-2018 IPR025827 Recombinase zinc beta ribbon domain TSH58p_07350 6b2dd31045273f5f6ee3c658b9bd66d8 548 Pfam PF07508 Recombinase 174 286 2.6E-21 T 14-10-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 TSH58p_00325 615a87f0a806ae464a287f6abecacf3c 437 Gene3D G3DSA:3.40.50.2000 232 396 1.7E-32 T 14-10-2018 TSH58p_00325 615a87f0a806ae464a287f6abecacf3c 437 Pfam PF13439 Glycosyltransferase Family 4 18 219 1.7E-16 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TSH58p_00325 615a87f0a806ae464a287f6abecacf3c 437 SUPERFAMILY SSF53756 7 416 3.14E-55 T 14-10-2018 TSH58p_00325 615a87f0a806ae464a287f6abecacf3c 437 Pfam PF00534 Glycosyl transferases group 1 236 391 1.1E-20 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 TSH58p_31520 e8105dc0801e5bd26b178d899a6a7e5e 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 3.7E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_31520 e8105dc0801e5bd26b178d899a6a7e5e 305 SUPERFAMILY SSF53850 91 299 3.26E-32 T 14-10-2018 TSH58p_31520 e8105dc0801e5bd26b178d899a6a7e5e 305 Gene3D G3DSA:3.40.190.290 91 300 5.6E-36 T 14-10-2018 TSH58p_31520 e8105dc0801e5bd26b178d899a6a7e5e 305 SUPERFAMILY SSF46785 4 110 1.25E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_31520 e8105dc0801e5bd26b178d899a6a7e5e 305 Gene3D G3DSA:1.10.10.10 1 90 6.4E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_31520 e8105dc0801e5bd26b178d899a6a7e5e 305 Pfam PF03466 LysR substrate binding domain 90 295 5.8E-33 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_12060 aaa8e03c04517a920e8390f536345089 482 Pfam PF13432 Tetratricopeptide repeat 413 466 7.0E-5 T 14-10-2018 TSH58p_12060 aaa8e03c04517a920e8390f536345089 482 Pfam PF13432 Tetratricopeptide repeat 162 197 0.012 T 14-10-2018 TSH58p_12060 aaa8e03c04517a920e8390f536345089 482 Pfam PF13432 Tetratricopeptide repeat 222 263 0.0012 T 14-10-2018 TSH58p_12060 aaa8e03c04517a920e8390f536345089 482 SUPERFAMILY SSF48452 228 456 1.18E-17 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_12060 aaa8e03c04517a920e8390f536345089 482 Gene3D G3DSA:1.25.40.10 153 298 1.8E-24 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_12060 aaa8e03c04517a920e8390f536345089 482 Gene3D G3DSA:1.25.40.10 339 478 4.9E-21 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_12060 aaa8e03c04517a920e8390f536345089 482 TIGRFAM TIGR03142 cytochro_ccmI: cytochrome c-type biogenesis protein CcmI 2 129 4.8E-29 T 14-10-2018 IPR017560 Cytochrome c-type biogenesis protein CcmI TSH58p_12060 aaa8e03c04517a920e8390f536345089 482 SMART SM00028 355 388 11.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_12060 aaa8e03c04517a920e8390f536345089 482 SMART SM00028 169 202 0.0083 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_12060 aaa8e03c04517a920e8390f536345089 482 SMART SM00028 240 273 280.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_12060 aaa8e03c04517a920e8390f536345089 482 SUPERFAMILY SSF48452 153 263 9.93E-14 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_07985 917250358105c476d425acca7ec76caf 203 Gene3D G3DSA:1.10.3480.10 13 202 3.1E-38 T 14-10-2018 TSH58p_07985 917250358105c476d425acca7ec76caf 203 Pfam PF02613 Nitrate reductase delta subunit 48 169 5.0E-30 T 14-10-2018 IPR020945 DMSO/Nitrate reductase chaperone TSH58p_07985 917250358105c476d425acca7ec76caf 203 SUPERFAMILY SSF89155 16 201 2.62E-50 T 14-10-2018 IPR036411 TorD-like superfamily TSH58p_30600 53ab4ae5cd7062d70506b284701bb77f 277 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_30600 53ab4ae5cd7062d70506b284701bb77f 277 Gene3D G3DSA:3.40.50.300 4 230 4.7E-68 T 14-10-2018 TSH58p_30600 53ab4ae5cd7062d70506b284701bb77f 277 Pfam PF00005 ABC transporter 26 166 5.5E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_30600 53ab4ae5cd7062d70506b284701bb77f 277 SUPERFAMILY SSF52540 6 241 1.23E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_30600 53ab4ae5cd7062d70506b284701bb77f 277 SMART SM00382 35 215 9.8E-19 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_04985 bfd3eba1d47479ee6eb897fd94f186e3 187 Pfam PF05194 UreE urease accessory protein, C-terminal domain 79 167 4.3E-22 T 14-10-2018 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0016151|GO:0019627|GO:0065003 TSH58p_04985 bfd3eba1d47479ee6eb897fd94f186e3 187 Pfam PF02814 UreE urease accessory protein, N-terminal domain 14 69 7.9E-16 T 14-10-2018 IPR004029 UreE urease accessory, N-terminal TSH58p_04985 bfd3eba1d47479ee6eb897fd94f186e3 187 Gene3D G3DSA:2.60.260.20 5 78 4.8E-15 T 14-10-2018 TSH58p_04985 bfd3eba1d47479ee6eb897fd94f186e3 187 Hamap MF_00822 Urease accessory protein UreE [ureE]. 6 147 22.015 T 14-10-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 TSH58p_04985 bfd3eba1d47479ee6eb897fd94f186e3 187 SUPERFAMILY SSF69737 79 146 1.96E-18 T 14-10-2018 IPR036675 UreE, C-terminal domain superfamily GO:0016151|GO:0019627|GO:0065003 TSH58p_04985 bfd3eba1d47479ee6eb897fd94f186e3 187 SUPERFAMILY SSF69287 20 78 6.8E-13 T 14-10-2018 IPR036118 UreE urease accessory, N-terminal domain superfamily TSH58p_04985 bfd3eba1d47479ee6eb897fd94f186e3 187 Gene3D G3DSA:3.30.70.790 79 151 2.1E-26 T 14-10-2018 IPR036675 UreE, C-terminal domain superfamily GO:0016151|GO:0019627|GO:0065003 TSH58p_04985 bfd3eba1d47479ee6eb897fd94f186e3 187 SMART SM00988 7 72 1.3E-14 T 14-10-2018 IPR004029 UreE urease accessory, N-terminal TSH58p_13005 72b8e36326aabc49d14680b842ac8467 428 Pfam PF13692 Glycosyl transferases group 1 244 390 3.6E-14 T 14-10-2018 TSH58p_13005 72b8e36326aabc49d14680b842ac8467 428 SUPERFAMILY SSF53756 31 421 5.76E-45 T 14-10-2018 TSH58p_13005 72b8e36326aabc49d14680b842ac8467 428 Pfam PF13579 Glycosyl transferase 4-like domain 44 226 2.3E-15 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TSH58p_13005 72b8e36326aabc49d14680b842ac8467 428 Gene3D G3DSA:3.40.50.2000 29 238 1.5E-14 T 14-10-2018 TSH58p_13005 72b8e36326aabc49d14680b842ac8467 428 Gene3D G3DSA:3.40.50.2000 239 406 6.2E-25 T 14-10-2018 TSH58p_00985 44824a001f994d6151cb5f48b975cb0b 526 SUPERFAMILY SSF48452 14 187 3.8E-21 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_00985 44824a001f994d6151cb5f48b975cb0b 526 SMART SM00028 97 130 0.66 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_00985 44824a001f994d6151cb5f48b975cb0b 526 SMART SM00028 29 62 230.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_00985 44824a001f994d6151cb5f48b975cb0b 526 SMART SM00028 63 96 0.87 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_00985 44824a001f994d6151cb5f48b975cb0b 526 SMART SM00028 200 233 86.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_00985 44824a001f994d6151cb5f48b975cb0b 526 Pfam PF13428 Tetratricopeptide repeat 102 139 4.6E-5 T 14-10-2018 TSH58p_00985 44824a001f994d6151cb5f48b975cb0b 526 Pfam PF13469 Sulfotransferase family 273 468 1.4E-33 T 14-10-2018 TSH58p_00985 44824a001f994d6151cb5f48b975cb0b 526 Gene3D G3DSA:1.25.40.10 11 124 8.3E-20 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_00985 44824a001f994d6151cb5f48b975cb0b 526 SUPERFAMILY SSF52540 270 506 6.83E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_00985 44824a001f994d6151cb5f48b975cb0b 526 Gene3D G3DSA:3.40.50.300 266 525 4.4E-57 T 14-10-2018 TSH58p_00985 44824a001f994d6151cb5f48b975cb0b 526 Pfam PF13432 Tetratricopeptide repeat 35 97 1.5E-5 T 14-10-2018 TSH58p_00985 44824a001f994d6151cb5f48b975cb0b 526 Gene3D G3DSA:1.25.40.10 125 245 1.2E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_18730 820a583ce64ba10b07c8129b479140f8 69 Gene3D G3DSA:3.10.20.30 3 69 1.1E-20 T 14-10-2018 IPR012675 Beta-grasp domain superfamily TSH58p_18730 820a583ce64ba10b07c8129b479140f8 69 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 5 69 6.2E-19 T 14-10-2018 IPR010035 ThiS, thiamine-biosynthesis TSH58p_18730 820a583ce64ba10b07c8129b479140f8 69 SUPERFAMILY SSF54285 4 68 1.45E-14 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TSH58p_18730 820a583ce64ba10b07c8129b479140f8 69 Pfam PF02597 ThiS family 9 69 2.8E-13 T 14-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TSH58p_00015 63e4811acaf72bd12611cefc08502275 334 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 21 326 1.9E-89 T 14-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane TSH58p_10160 d4bae692202acc38b96f6a2887a29969 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 124 305 1.9E-29 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_10160 d4bae692202acc38b96f6a2887a29969 307 Gene3D G3DSA:1.10.3720.10 95 303 4.6E-19 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_10160 d4bae692202acc38b96f6a2887a29969 307 SUPERFAMILY SSF161098 101 288 1.57E-26 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_10160 d4bae692202acc38b96f6a2887a29969 307 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 37 83 1.9E-15 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TSH58p_28460 e2fdc79da928de202c8ec1d2cacb6cca 55 Pfam PF00471 Ribosomal protein L33 8 53 4.3E-15 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_28460 e2fdc79da928de202c8ec1d2cacb6cca 55 Gene3D G3DSA:2.20.28.120 1 55 1.8E-26 T 14-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_28460 e2fdc79da928de202c8ec1d2cacb6cca 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 21 40 - T 14-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_28460 e2fdc79da928de202c8ec1d2cacb6cca 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 55 7.3E-22 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_28460 e2fdc79da928de202c8ec1d2cacb6cca 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 53 12.873 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_28460 e2fdc79da928de202c8ec1d2cacb6cca 55 SUPERFAMILY SSF57829 1 53 3.97E-17 T 14-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TSH58p_01850 96d89b0b2f15b2a6345b8bccfe4bf059 255 Pfam PF13247 4Fe-4S dicluster domain 99 192 8.2E-30 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_01850 96d89b0b2f15b2a6345b8bccfe4bf059 255 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 137 148 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_01850 96d89b0b2f15b2a6345b8bccfe4bf059 255 Gene3D G3DSA:3.30.70.20 111 163 3.5E-68 T 14-10-2018 TSH58p_01850 96d89b0b2f15b2a6345b8bccfe4bf059 255 SUPERFAMILY SSF54862 49 225 1.57E-70 T 14-10-2018 TSH58p_01850 96d89b0b2f15b2a6345b8bccfe4bf059 255 Gene3D G3DSA:3.30.70.20 51 225 3.5E-68 T 14-10-2018 TSH58p_25290 b2d46fc10399ec8d181b4045e61e36fc 654 Pfam PF03389 MobA/MobL family 24 145 8.2E-20 T 14-10-2018 IPR005053 MobA/MobL protein TSH58p_05615 845508e99148f40823c217f3e43cb874 67 SUPERFAMILY SSF55008 4 62 1.13E-15 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 TSH58p_05615 845508e99148f40823c217f3e43cb874 67 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 36 - T 14-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 TSH58p_05615 845508e99148f40823c217f3e43cb874 67 Gene3D G3DSA:3.30.70.100 4 62 3.9E-20 T 14-10-2018 TSH58p_05615 845508e99148f40823c217f3e43cb874 67 Pfam PF00403 Heavy-metal-associated domain 4 62 5.2E-14 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TSH58p_17130 c87a697a977428acd66e349e7272e062 137 Gene3D G3DSA:3.30.428.10 2 137 1.3E-41 T 14-10-2018 IPR036265 HIT-like superfamily TSH58p_17130 c87a697a977428acd66e349e7272e062 137 PIRSF PIRSF000714 3 137 5.3E-51 T 14-10-2018 IPR026026 Histidine triad hydrolase, Hint-type TSH58p_17130 c87a697a977428acd66e349e7272e062 137 SUPERFAMILY SSF54197 1 135 2.89E-35 T 14-10-2018 IPR036265 HIT-like superfamily TSH58p_17130 c87a697a977428acd66e349e7272e062 137 Pfam PF01230 HIT domain 10 100 7.8E-16 T 14-10-2018 IPR001310 Histidine triad (HIT) protein TSH58p_27895 b890b6fe1b5818755865641c2f5bb313 161 Pfam PF13411 MerR HTH family regulatory protein 30 93 4.2E-17 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_27895 b890b6fe1b5818755865641c2f5bb313 161 Gene3D G3DSA:1.10.1660.10 25 148 1.8E-27 T 14-10-2018 TSH58p_27895 b890b6fe1b5818755865641c2f5bb313 161 SMART SM00422 29 96 3.2E-21 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_27895 b890b6fe1b5818755865641c2f5bb313 161 SUPERFAMILY SSF46955 29 137 9.89E-26 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily TSH58p_00055 cc2d0e575dc5229b1e574e9573bc6e63 269 Gene3D G3DSA:3.40.190.10 44 263 1.1E-41 T 14-10-2018 TSH58p_00055 cc2d0e575dc5229b1e574e9573bc6e63 269 SUPERFAMILY SSF53850 38 268 1.8E-45 T 14-10-2018 TSH58p_00055 cc2d0e575dc5229b1e574e9573bc6e63 269 SMART SM00062 37 267 3.2E-31 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_00055 cc2d0e575dc5229b1e574e9573bc6e63 269 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 264 4.6E-40 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_00055 cc2d0e575dc5229b1e574e9573bc6e63 269 Gene3D G3DSA:3.40.190.10 123 224 1.1E-41 T 14-10-2018 TSH58p_07195 9c5c96fa7a20b69aee7e7633045df061 162 Gene3D G3DSA:2.30.110.60 3 152 2.4E-5 T 14-10-2018 TSH58p_25330 b0b28501f71291600dda4249bd25b232 960 Pfam PF08665 PglZ domain 484 657 1.1E-14 T 14-10-2018 IPR013973 PglZ domain TSH58p_19365 695d44afcadcd2edee27b35d99b6e7ae 206 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 30 160 7.6E-23 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ TSH58p_14355 9f835b02466fe6bff0246985426af680 601 SUPERFAMILY SSF56519 81 219 1.57E-36 T 14-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 TSH58p_14355 9f835b02466fe6bff0246985426af680 601 Gene3D G3DSA:3.40.710.10 278 459 2.4E-91 T 14-10-2018 TSH58p_14355 9f835b02466fe6bff0246985426af680 601 Gene3D G3DSA:3.30.450.330 218 545 2.4E-91 T 14-10-2018 TSH58p_14355 9f835b02466fe6bff0246985426af680 601 Pfam PF00905 Penicillin binding protein transpeptidase domain 244 539 5.1E-58 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 TSH58p_14355 9f835b02466fe6bff0246985426af680 601 SUPERFAMILY SSF56601 217 551 1.04E-82 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TSH58p_14355 9f835b02466fe6bff0246985426af680 601 Pfam PF03717 Penicillin-binding Protein dimerisation domain 81 192 5.5E-12 T 14-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 TSH58p_13185 6b1a5db22a41363d8ac94e4d482980a2 229 Gene3D G3DSA:1.10.10.10 1 64 3.2E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_13185 6b1a5db22a41363d8ac94e4d482980a2 229 Pfam PF13280 WYL domain 138 227 3.0E-15 T 14-10-2018 IPR026881 WYL domain TSH58p_13185 6b1a5db22a41363d8ac94e4d482980a2 229 SUPERFAMILY SSF46785 3 62 1.27E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_13185 6b1a5db22a41363d8ac94e4d482980a2 229 Pfam PF08279 HTH domain 6 59 3.6E-19 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 TSH58p_08755 ee5c093aaf40c81ae1530f39a5b6edba 113 SUPERFAMILY SSF52833 5 106 3.22E-36 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_08755 ee5c093aaf40c81ae1530f39a5b6edba 113 Gene3D G3DSA:3.40.30.10 9 104 1.0E-34 T 14-10-2018 TSH58p_08755 ee5c093aaf40c81ae1530f39a5b6edba 113 Pfam PF00462 Glutaredoxin 19 83 1.2E-19 T 14-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 TSH58p_08755 ee5c093aaf40c81ae1530f39a5b6edba 113 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 7 103 5.6E-47 T 14-10-2018 IPR004480 Monothiol glutaredoxin-related TSH58p_08755 ee5c093aaf40c81ae1530f39a5b6edba 113 PIRSF PIRSF005894 1 110 2.0E-50 T 14-10-2018 IPR014434 Monothiol glutaredoxin GO:0015036 Reactome: R-HSA-1362409 TSH58p_14220 c2b12e4828c6bf71a2a416637567409d 681 Gene3D G3DSA:3.90.230.10 383 680 1.7E-101 T 14-10-2018 TSH58p_14220 c2b12e4828c6bf71a2a416637567409d 681 SUPERFAMILY SSF53092 82 210 1.92E-13 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TSH58p_14220 c2b12e4828c6bf71a2a416637567409d 681 Pfam PF00557 Metallopeptidase family M24 393 605 8.4E-49 T 14-10-2018 IPR000994 Peptidase M24 TSH58p_14220 c2b12e4828c6bf71a2a416637567409d 681 Gene3D G3DSA:3.40.350.10 82 227 4.4E-38 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TSH58p_14220 c2b12e4828c6bf71a2a416637567409d 681 Gene3D G3DSA:3.40.350.10 228 372 9.0E-28 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TSH58p_14220 c2b12e4828c6bf71a2a416637567409d 681 SUPERFAMILY SSF55920 386 641 1.31E-59 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like TSH58p_14220 c2b12e4828c6bf71a2a416637567409d 681 Pfam PF01321 Creatinase/Prolidase N-terminal domain 88 218 2.1E-18 T 14-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 TSH58p_14220 c2b12e4828c6bf71a2a416637567409d 681 Pfam PF16188 C-terminal region of peptidase_M24 616 679 1.2E-22 T 14-10-2018 IPR032416 Peptidase M24, C-terminal domain TSH58p_14220 c2b12e4828c6bf71a2a416637567409d 681 Pfam PF16189 Creatinase/Prolidase N-terminal domain 229 389 4.3E-39 T 14-10-2018 TSH58p_04595 42166fdda1556dfcc8dd9a91fa019dae 426 Pfam PF01266 FAD dependent oxidoreductase 31 382 3.5E-56 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TSH58p_04595 42166fdda1556dfcc8dd9a91fa019dae 426 Gene3D G3DSA:3.30.9.10 123 345 1.4E-74 T 14-10-2018 TSH58p_04595 42166fdda1556dfcc8dd9a91fa019dae 426 SUPERFAMILY SSF51905 30 421 2.59E-42 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_04595 42166fdda1556dfcc8dd9a91fa019dae 426 Gene3D G3DSA:3.50.50.60 31 384 1.4E-74 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_28470 e0a1323b64f8190e003214b5ffcaad2c 765 SMART SM00316 637 720 9.4E-8 T 14-10-2018 IPR022967 RNA-binding domain, S1 TSH58p_28470 e0a1323b64f8190e003214b5ffcaad2c 765 Pfam PF00773 RNB domain 260 586 4.7E-93 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 TSH58p_28470 e0a1323b64f8190e003214b5ffcaad2c 765 ProSitePatterns PS01175 Ribonuclease II family signature. 558 582 - T 14-10-2018 IPR022966 Ribonuclease II/R, conserved site TSH58p_28470 e0a1323b64f8190e003214b5ffcaad2c 765 TIGRFAM TIGR02063 RNase_R: ribonuclease R 17 719 5.3E-212 T 14-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 TSH58p_28470 e0a1323b64f8190e003214b5ffcaad2c 765 SMART SM00955 260 591 7.4E-160 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 TSH58p_28470 e0a1323b64f8190e003214b5ffcaad2c 765 Pfam PF00575 S1 RNA binding domain 637 709 3.6E-10 T 14-10-2018 IPR003029 S1 domain GO:0003676 TSH58p_28470 e0a1323b64f8190e003214b5ffcaad2c 765 SUPERFAMILY SSF50249 230 637 1.94E-132 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_28470 e0a1323b64f8190e003214b5ffcaad2c 765 Gene3D G3DSA:2.40.50.140 641 729 4.9E-16 T 14-10-2018 TSH58p_28470 e0a1323b64f8190e003214b5ffcaad2c 765 SUPERFAMILY SSF50249 637 714 1.8E-18 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_28470 e0a1323b64f8190e003214b5ffcaad2c 765 Hamap MF_01895 Ribonuclease R [rnr]. 35 720 54.72 T 14-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 TSH58p_28470 e0a1323b64f8190e003214b5ffcaad2c 765 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 127 709 1.2E-154 T 14-10-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 TSH58p_20455 1d9b44163b82f7d679be3e0430993530 120 Pfam PF11162 Protein of unknown function (DUF2946) 6 117 1.0E-7 T 14-10-2018 IPR021333 Protein of unknown function DUF2946 TSH58p_02285 84e8114e4a283fddf60968a70f8c3c7d 202 Pfam PF02669 K+-transporting ATPase, c chain 6 196 5.7E-73 T 14-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 TSH58p_02285 84e8114e4a283fddf60968a70f8c3c7d 202 PIRSF PIRSF001296 1 202 7.5E-75 T 14-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 TSH58p_02285 84e8114e4a283fddf60968a70f8c3c7d 202 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 4 197 6.6E-70 T 14-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 TSH58p_02285 84e8114e4a283fddf60968a70f8c3c7d 202 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 2 198 36.39 T 14-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 TSH58p_19635 94aac60ffcd51c1a767dd56aca5bee78 305 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 290 1.5E-39 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_03720 7293808ee5e64fdbcea22d80241a26d4 424 Gene3D G3DSA:3.30.70.270 10 159 9.3E-41 T 14-10-2018 TSH58p_03720 7293808ee5e64fdbcea22d80241a26d4 424 Pfam PF13438 Domain of unknown function (DUF4113) 374 422 1.4E-19 T 14-10-2018 IPR025188 Domain of unknown function DUF4113 TSH58p_03720 7293808ee5e64fdbcea22d80241a26d4 424 Gene3D G3DSA:1.10.150.20 183 236 1.0E-8 T 14-10-2018 TSH58p_03720 7293808ee5e64fdbcea22d80241a26d4 424 SUPERFAMILY SSF56672 5 241 1.78E-65 T 14-10-2018 TSH58p_03720 7293808ee5e64fdbcea22d80241a26d4 424 Pfam PF00817 impB/mucB/samB family 10 154 6.8E-31 T 14-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 TSH58p_03720 7293808ee5e64fdbcea22d80241a26d4 424 Gene3D G3DSA:2.30.40.20 15 78 9.3E-41 T 14-10-2018 TSH58p_03720 7293808ee5e64fdbcea22d80241a26d4 424 Pfam PF11799 impB/mucB/samB family C-terminal domain 243 355 2.8E-9 T 14-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 TSH58p_31035 5181b25f0741b206cf4ca59b6aa9394b 327 SMART SM00829 12 325 2.4E-44 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TSH58p_31035 5181b25f0741b206cf4ca59b6aa9394b 327 SUPERFAMILY SSF51735 115 263 8.32E-51 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_31035 5181b25f0741b206cf4ca59b6aa9394b 327 Gene3D G3DSA:3.40.50.720 126 271 3.9E-114 T 14-10-2018 TSH58p_31035 5181b25f0741b206cf4ca59b6aa9394b 327 Pfam PF00107 Zinc-binding dehydrogenase 154 259 4.6E-31 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TSH58p_31035 5181b25f0741b206cf4ca59b6aa9394b 327 SUPERFAMILY SSF50129 3 147 5.33E-39 T 14-10-2018 IPR011032 GroES-like superfamily TSH58p_31035 5181b25f0741b206cf4ca59b6aa9394b 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 90 7.4E-9 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TSH58p_31035 5181b25f0741b206cf4ca59b6aa9394b 327 Gene3D G3DSA:3.90.180.10 13 321 3.9E-114 T 14-10-2018 TSH58p_17325 d916c75ffb93ba0140bce4b1deac83f4 112 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 4 100 28.258 T 14-10-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 TSH58p_17325 d916c75ffb93ba0140bce4b1deac83f4 112 Pfam PF00216 Bacterial DNA-binding protein 6 95 7.3E-26 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_17325 d916c75ffb93ba0140bce4b1deac83f4 112 Gene3D G3DSA:4.10.520.10 4 102 1.3E-29 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 TSH58p_17325 d916c75ffb93ba0140bce4b1deac83f4 112 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 5 97 9.3E-42 T 14-10-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 TSH58p_17325 d916c75ffb93ba0140bce4b1deac83f4 112 SMART SM00411 6 95 9.8E-34 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_17325 d916c75ffb93ba0140bce4b1deac83f4 112 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 51 70 - T 14-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 TSH58p_17325 d916c75ffb93ba0140bce4b1deac83f4 112 PRINTS PR01727 Prokaryotic integration host factor signature 63 76 2.0E-12 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_17325 d916c75ffb93ba0140bce4b1deac83f4 112 PRINTS PR01727 Prokaryotic integration host factor signature 79 93 2.0E-12 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_17325 d916c75ffb93ba0140bce4b1deac83f4 112 PRINTS PR01727 Prokaryotic integration host factor signature 45 60 2.0E-12 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSH58p_17325 d916c75ffb93ba0140bce4b1deac83f4 112 SUPERFAMILY SSF47729 6 96 2.21E-26 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 TSH58p_05435 1e755f31f22ddbc9d56ea7bfcbba6a2d 393 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 239 252 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TSH58p_05435 1e755f31f22ddbc9d56ea7bfcbba6a2d 393 Pfam PF00155 Aminotransferase class I and II 36 388 1.8E-42 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSH58p_05435 1e755f31f22ddbc9d56ea7bfcbba6a2d 393 SUPERFAMILY SSF53383 13 390 6.92E-85 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_05435 1e755f31f22ddbc9d56ea7bfcbba6a2d 393 Gene3D G3DSA:3.40.640.10 20 392 1.6E-82 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_12135 87bc86f6ccd641c249034f0f45b9b282 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 157 176 9.6E-68 T 14-10-2018 TSH58p_12135 87bc86f6ccd641c249034f0f45b9b282 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 77 100 9.6E-68 T 14-10-2018 TSH58p_12135 87bc86f6ccd641c249034f0f45b9b282 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 194 217 9.6E-68 T 14-10-2018 TSH58p_12135 87bc86f6ccd641c249034f0f45b9b282 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 28 49 9.6E-68 T 14-10-2018 TSH58p_12135 87bc86f6ccd641c249034f0f45b9b282 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 102 120 9.6E-68 T 14-10-2018 TSH58p_12135 87bc86f6ccd641c249034f0f45b9b282 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 54 71 9.6E-68 T 14-10-2018 TSH58p_12135 87bc86f6ccd641c249034f0f45b9b282 221 TIGRFAM TIGR01190 ccmB: heme exporter protein CcmB 7 217 2.3E-84 T 14-10-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria TSH58p_12135 87bc86f6ccd641c249034f0f45b9b282 221 PIRSF PIRSF002764 1 221 3.3E-82 T 14-10-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria TSH58p_12135 87bc86f6ccd641c249034f0f45b9b282 221 Pfam PF03379 CcmB protein 5 217 3.8E-83 T 14-10-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSH58p_30370 7a5b412bcc90cdd5629bfb6bb6432c0f 640 SMART SM00327 450 632 1.4E-16 T 14-10-2018 IPR002035 von Willebrand factor, type A TSH58p_30370 7a5b412bcc90cdd5629bfb6bb6432c0f 640 Gene3D G3DSA:3.40.50.410 444 624 5.6E-17 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TSH58p_30370 7a5b412bcc90cdd5629bfb6bb6432c0f 640 Pfam PF00092 von Willebrand factor type A domain 453 602 3.2E-7 T 14-10-2018 IPR002035 von Willebrand factor, type A TSH58p_30370 7a5b412bcc90cdd5629bfb6bb6432c0f 640 SUPERFAMILY SSF53300 451 636 2.7E-22 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TSH58p_13000 3e3e4a883f67ee9513fd9b07f7ebd18b 399 SUPERFAMILY SSF53756 27 373 7.85E-43 T 14-10-2018 TSH58p_13000 3e3e4a883f67ee9513fd9b07f7ebd18b 399 Gene3D G3DSA:3.40.50.2000 175 355 1.2E-33 T 14-10-2018 TSH58p_13000 3e3e4a883f67ee9513fd9b07f7ebd18b 399 Pfam PF00534 Glycosyl transferases group 1 198 354 7.8E-25 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 TSH58p_13000 3e3e4a883f67ee9513fd9b07f7ebd18b 399 Gene3D G3DSA:3.40.50.2000 49 174 1.2E-33 T 14-10-2018 TSH58p_32135 afc49e34a2245429774d79ca9a3a7e44 388 Gene3D G3DSA:3.40.50.1970 14 193 4.3E-40 T 14-10-2018 TSH58p_32135 afc49e34a2245429774d79ca9a3a7e44 388 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 182 210 - T 14-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 TSH58p_32135 afc49e34a2245429774d79ca9a3a7e44 388 Gene3D G3DSA:1.20.1090.10 194 388 5.9E-62 T 14-10-2018 TSH58p_32135 afc49e34a2245429774d79ca9a3a7e44 388 SUPERFAMILY SSF56796 22 388 3.4E-102 T 14-10-2018 TSH58p_32135 afc49e34a2245429774d79ca9a3a7e44 388 Pfam PF00465 Iron-containing alcohol dehydrogenase 25 380 1.8E-99 T 14-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 TSH58p_17310 cdcadd164e88239718c48829d25bbf00 61 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 1.9E-26 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_17310 cdcadd164e88239718c48829d25bbf00 61 Pfam PF01783 Ribosomal L32p protein family 2 56 5.9E-27 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_17310 cdcadd164e88239718c48829d25bbf00 61 SUPERFAMILY SSF57829 1 55 2.56E-23 T 14-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TSH58p_17310 cdcadd164e88239718c48829d25bbf00 61 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 21.21 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_26130 e8c8780562683b56335a1a598c827b14 503 Pfam PF02872 5'-nucleotidase, C-terminal domain 310 465 8.3E-42 T 14-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSH58p_26130 e8c8780562683b56335a1a598c827b14 503 PRINTS PR01607 Apyrase family signature 439 458 4.6E-9 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSH58p_26130 e8c8780562683b56335a1a598c827b14 503 PRINTS PR01607 Apyrase family signature 366 389 4.6E-9 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSH58p_26130 e8c8780562683b56335a1a598c827b14 503 Gene3D G3DSA:3.90.780.10 309 502 3.7E-52 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSH58p_26130 e8c8780562683b56335a1a598c827b14 503 SUPERFAMILY SSF56300 52 302 7.87E-24 T 14-10-2018 TSH58p_26130 e8c8780562683b56335a1a598c827b14 503 Gene3D G3DSA:3.60.21.10 35 232 1.6E-24 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like TSH58p_26130 e8c8780562683b56335a1a598c827b14 503 SUPERFAMILY SSF55816 307 500 1.44E-53 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSH58p_32435 de5a2dcc696be732370723ac4eb7ed47 360 Gene3D G3DSA:3.40.190.10 160 183 2.1E-11 T 14-10-2018 TSH58p_32435 de5a2dcc696be732370723ac4eb7ed47 360 Pfam PF13531 Bacterial extracellular solute-binding protein 165 218 3.2E-7 T 14-10-2018 TSH58p_32435 de5a2dcc696be732370723ac4eb7ed47 360 SUPERFAMILY SSF53850 158 238 1.58E-12 T 14-10-2018 TSH58p_32435 de5a2dcc696be732370723ac4eb7ed47 360 Gene3D G3DSA:3.40.190.10 184 220 2.1E-11 T 14-10-2018 TSH58p_28585 8c8b20dd37b8640dd32b17d0b7293b05 286 SUPERFAMILY SSF161098 20 274 6.73E-50 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_28585 8c8b20dd37b8640dd32b17d0b7293b05 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 276 3.0E-7 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_28585 8c8b20dd37b8640dd32b17d0b7293b05 286 Gene3D G3DSA:1.10.3720.10 12 285 2.6E-45 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_13135 56947b12e3695882fdb3f202674edc2e 231 SUPERFAMILY SSF46565 159 218 6.67E-6 T 14-10-2018 IPR036869 Chaperone J-domain superfamily TSH58p_14325 b2278bad076e2c63c0b79fb6c2172bd8 379 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 5 361 1.9E-78 T 14-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_14325 b2278bad076e2c63c0b79fb6c2172bd8 379 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 9 144 6.1E-28 T 14-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_14325 b2278bad076e2c63c0b79fb6c2172bd8 379 Gene3D G3DSA:3.40.50.2000 10 356 1.1E-93 T 14-10-2018 TSH58p_14325 b2278bad076e2c63c0b79fb6c2172bd8 379 Gene3D G3DSA:3.40.50.2000 168 350 1.1E-93 T 14-10-2018 TSH58p_14325 b2278bad076e2c63c0b79fb6c2172bd8 379 SUPERFAMILY SSF53756 8 366 1.28E-95 T 14-10-2018 TSH58p_14325 b2278bad076e2c63c0b79fb6c2172bd8 379 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 9 366 31.478 T 14-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_14325 b2278bad076e2c63c0b79fb6c2172bd8 379 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 191 357 4.3E-33 T 14-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 TSH58p_26015 558ad5ac90a9eb2eef6a4ab7cde74b5c 100 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 2.9E-25 T 14-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_26015 558ad5ac90a9eb2eef6a4ab7cde74b5c 100 SUPERFAMILY SSF143800 1 84 8.04E-29 T 14-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_26015 558ad5ac90a9eb2eef6a4ab7cde74b5c 100 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 68 21.412 T 14-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_26015 558ad5ac90a9eb2eef6a4ab7cde74b5c 100 Gene3D G3DSA:2.30.170.40 2 76 3.7E-29 T 14-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_26015 558ad5ac90a9eb2eef6a4ab7cde74b5c 100 Pfam PF00830 Ribosomal L28 family 3 61 4.4E-26 T 14-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_32245 178a0bda3dbb7d632dac4740e1c866b7 238 Pfam PF10531 SLBB domain 117 161 6.4E-8 T 14-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_32245 178a0bda3dbb7d632dac4740e1c866b7 238 Gene3D G3DSA:3.30.1950.10 59 113 4.5E-19 T 14-10-2018 TSH58p_32245 178a0bda3dbb7d632dac4740e1c866b7 238 Pfam PF02563 Polysaccharide biosynthesis/export protein 36 108 6.2E-12 T 14-10-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 TSH58p_32245 178a0bda3dbb7d632dac4740e1c866b7 238 Gene3D G3DSA:3.10.560.10 114 201 4.5E-19 T 14-10-2018 TSH58p_11935 64842ff18cfff5eed51cc5ef996e81f9 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 7.2E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_11935 64842ff18cfff5eed51cc5ef996e81f9 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 7.2E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_11935 64842ff18cfff5eed51cc5ef996e81f9 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 7.2E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_11935 64842ff18cfff5eed51cc5ef996e81f9 302 SUPERFAMILY SSF46785 5 113 1.61E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_11935 64842ff18cfff5eed51cc5ef996e81f9 302 SUPERFAMILY SSF53850 94 289 8.01E-29 T 14-10-2018 TSH58p_11935 64842ff18cfff5eed51cc5ef996e81f9 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 2.2E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_11935 64842ff18cfff5eed51cc5ef996e81f9 302 Gene3D G3DSA:3.40.190.10 97 269 1.0E-55 T 14-10-2018 TSH58p_11935 64842ff18cfff5eed51cc5ef996e81f9 302 Gene3D G3DSA:1.10.10.10 2 86 2.6E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_11935 64842ff18cfff5eed51cc5ef996e81f9 302 Pfam PF03466 LysR substrate binding domain 94 286 3.1E-31 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_11935 64842ff18cfff5eed51cc5ef996e81f9 302 Gene3D G3DSA:3.40.190.10 163 262 1.0E-55 T 14-10-2018 TSH58p_04265 9fcbde87fd78d50bba7f162e2e9f2ab4 160 Gene3D G3DSA:2.60.120.1140 30 159 1.2E-47 T 14-10-2018 IPR038695 Saro_0823-like superfamily TSH58p_04265 9fcbde87fd78d50bba7f162e2e9f2ab4 160 Pfam PF02643 Uncharacterized ACR, COG1430 50 152 1.7E-34 T 14-10-2018 IPR003795 Protein of unknown function DUF192 TSH58p_12665 bcdf8d010336b521c151ba0e7529cc94 159 Gene3D G3DSA:2.60.40.790 33 136 3.0E-20 T 14-10-2018 IPR008978 HSP20-like chaperone TSH58p_12665 bcdf8d010336b521c151ba0e7529cc94 159 Pfam PF00011 Hsp20/alpha crystallin family 44 134 7.7E-17 T 14-10-2018 IPR002068 Alpha crystallin/Hsp20 domain TSH58p_12665 bcdf8d010336b521c151ba0e7529cc94 159 SUPERFAMILY SSF49764 31 135 1.53E-19 T 14-10-2018 IPR008978 HSP20-like chaperone TSH58p_20095 cbdd0cbf193337198a2b55c5b17f5384 124 SUPERFAMILY SSF53383 49 121 1.32E-6 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_20095 cbdd0cbf193337198a2b55c5b17f5384 124 Gene3D G3DSA:3.90.1150.10 30 123 3.6E-5 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_08440 20f9e7748e4e22942c4baff4962c5a83 637 SUPERFAMILY SSF53474 331 579 3.49E-16 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_08440 20f9e7748e4e22942c4baff4962c5a83 637 Gene3D G3DSA:3.40.50.1820 329 600 8.1E-22 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_29355 89d83bb0d679884682b277a6e6e4c46a 265 Pfam PF13560 Helix-turn-helix domain 10 91 5.6E-18 T 14-10-2018 TSH58p_29355 89d83bb0d679884682b277a6e6e4c46a 265 Gene3D G3DSA:1.10.260.40 31 90 2.5E-6 T 14-10-2018 TSH58p_29355 89d83bb0d679884682b277a6e6e4c46a 265 SUPERFAMILY SSF47413 35 87 1.5E-5 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_29355 89d83bb0d679884682b277a6e6e4c46a 265 SMART SM00530 14 88 3.9E-6 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_29355 89d83bb0d679884682b277a6e6e4c46a 265 Gene3D G3DSA:3.30.450.180 108 259 1.1E-12 T 14-10-2018 TSH58p_09100 75e4c970a8f525d49cc2f2dda8e2d137 73 SUPERFAMILY SSF52833 6 67 1.74E-11 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_09100 75e4c970a8f525d49cc2f2dda8e2d137 73 Gene3D G3DSA:3.40.30.10 4 71 3.1E-10 T 14-10-2018 TSH58p_09100 75e4c970a8f525d49cc2f2dda8e2d137 73 Pfam PF00578 AhpC/TSA family 12 67 1.5E-6 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TSH58p_05600 8c61bb3f4a9369b2b0ac4b388451ebc3 628 Gene3D G3DSA:1.10.4030.30 43 184 2.3E-8 T 14-10-2018 TSH58p_05600 8c61bb3f4a9369b2b0ac4b388451ebc3 628 Gene3D G3DSA:3.10.50.40 268 351 6.2E-10 T 14-10-2018 TSH58p_05600 8c61bb3f4a9369b2b0ac4b388451ebc3 628 Pfam PF13624 SurA N-terminal domain 1 161 4.8E-44 T 14-10-2018 TSH58p_05600 8c61bb3f4a9369b2b0ac4b388451ebc3 628 Gene3D G3DSA:1.10.4030.30 232 364 6.2E-10 T 14-10-2018 TSH58p_05600 8c61bb3f4a9369b2b0ac4b388451ebc3 628 SUPERFAMILY SSF54534 224 348 6.02E-9 T 14-10-2018 TSH58p_05600 8c61bb3f4a9369b2b0ac4b388451ebc3 628 Pfam PF13145 PPIC-type PPIASE domain 248 363 1.4E-22 T 14-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 TSH58p_05600 8c61bb3f4a9369b2b0ac4b388451ebc3 628 Pfam PF13145 PPIC-type PPIASE domain 390 478 2.7E-7 T 14-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 TSH58p_05600 8c61bb3f4a9369b2b0ac4b388451ebc3 628 SUPERFAMILY SSF109998 40 293 4.97E-25 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily TSH58p_08565 b0dab5468dfa03552a9b078299998955 228 SUPERFAMILY SSF55821 21 222 8.01E-79 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily TSH58p_08565 b0dab5468dfa03552a9b078299998955 228 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 28 219 2.9E-71 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TSH58p_08565 b0dab5468dfa03552a9b078299998955 228 Gene3D G3DSA:3.90.870.10 12 227 2.3E-83 T 14-10-2018 TSH58p_08565 b0dab5468dfa03552a9b078299998955 228 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 31 219 2.9E-77 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TSH58p_08565 b0dab5468dfa03552a9b078299998955 228 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 24 226 39.79 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TSH58p_18275 4cbaca643fad37c91f84eeb52ffaef57 787 Pfam PF01757 Acyltransferase family 410 745 2.6E-9 T 14-10-2018 IPR002656 Acyltransferase 3 GO:0016747 TSH58p_18275 4cbaca643fad37c91f84eeb52ffaef57 787 Pfam PF01757 Acyltransferase family 23 365 1.1E-24 T 14-10-2018 IPR002656 Acyltransferase 3 GO:0016747 TSH58p_27110 39741802b8d150ac9a7f6ecfa1d3afe3 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.0E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_27110 39741802b8d150ac9a7f6ecfa1d3afe3 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.0E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_27110 39741802b8d150ac9a7f6ecfa1d3afe3 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.0E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_27110 39741802b8d150ac9a7f6ecfa1d3afe3 311 Gene3D G3DSA:3.40.190.10 169 269 2.7E-9 T 14-10-2018 TSH58p_27110 39741802b8d150ac9a7f6ecfa1d3afe3 311 SUPERFAMILY SSF53850 92 302 2.17E-22 T 14-10-2018 TSH58p_27110 39741802b8d150ac9a7f6ecfa1d3afe3 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.2E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_27110 39741802b8d150ac9a7f6ecfa1d3afe3 311 SUPERFAMILY SSF46785 1 79 2.27E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_27110 39741802b8d150ac9a7f6ecfa1d3afe3 311 Pfam PF03466 LysR substrate binding domain 90 297 2.2E-23 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_27110 39741802b8d150ac9a7f6ecfa1d3afe3 311 Gene3D G3DSA:3.40.190.10 161 292 2.7E-9 T 14-10-2018 TSH58p_27110 39741802b8d150ac9a7f6ecfa1d3afe3 311 Gene3D G3DSA:1.10.10.10 1 89 1.1E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_28135 b6f7c226a289a0d3789daacf80bfe76a 203 Gene3D G3DSA:3.40.50.1240 37 190 1.2E-26 T 14-10-2018 IPR029033 Histidine phosphatase superfamily TSH58p_28135 b6f7c226a289a0d3789daacf80bfe76a 203 SMART SM00855 47 170 5.6E-5 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TSH58p_28135 b6f7c226a289a0d3789daacf80bfe76a 203 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 48 118 2.3E-7 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TSH58p_28135 b6f7c226a289a0d3789daacf80bfe76a 203 SUPERFAMILY SSF53254 48 174 1.07E-17 T 14-10-2018 IPR029033 Histidine phosphatase superfamily TSH58p_15835 c692e2e6074b62f4668da541d54e4d67 201 Gene3D G3DSA:3.40.50.300 5 200 1.1E-44 T 14-10-2018 TSH58p_15835 c692e2e6074b62f4668da541d54e4d67 201 Pfam PF00005 ABC transporter 12 143 4.8E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_15835 c692e2e6074b62f4668da541d54e4d67 201 SUPERFAMILY SSF52540 4 193 5.15E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_15835 c692e2e6074b62f4668da541d54e4d67 201 SMART SM00382 21 192 1.4E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_32105 e3cb5f883569e486b31cab15656e8957 467 SUPERFAMILY SSF55729 322 460 3.83E-7 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_32105 e3cb5f883569e486b31cab15656e8957 467 Pfam PF06527 TniQ 35 154 1.6E-21 T 14-10-2018 IPR009492 TniQ TSH58p_09735 be9239293ba9233198250deaa1125e8b 294 SUPERFAMILY SSF161098 55 281 7.46E-51 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_09735 be9239293ba9233198250deaa1125e8b 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 291 1.5E-12 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_09735 be9239293ba9233198250deaa1125e8b 294 Gene3D G3DSA:1.10.3720.10 51 292 2.2E-58 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_14770 b31bef48c825a6be6f9e26b2812cb902 264 SUPERFAMILY SSF88697 8 70 2.98E-13 T 14-10-2018 IPR015947 PUA-like superfamily TSH58p_14770 b31bef48c825a6be6f9e26b2812cb902 264 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 16 241 6.4E-31 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 TSH58p_14770 b31bef48c825a6be6f9e26b2812cb902 264 Gene3D G3DSA:2.40.240.20 7 74 1.0E-21 T 14-10-2018 TSH58p_14770 b31bef48c825a6be6f9e26b2812cb902 264 PIRSF PIRSF015601 6 243 5.0E-51 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 TSH58p_14770 b31bef48c825a6be6f9e26b2812cb902 264 Gene3D G3DSA:3.40.1280.10 77 244 8.0E-48 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TSH58p_14770 b31bef48c825a6be6f9e26b2812cb902 264 SUPERFAMILY SSF75217 80 243 5.23E-43 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases TSH58p_14770 b31bef48c825a6be6f9e26b2812cb902 264 Pfam PF04452 RNA methyltransferase 23 238 7.0E-50 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 TSH58p_23895 df645c78d01cffefef5dc16df30c66b3 156 SMART SM00448 19 135 2.8E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_23895 df645c78d01cffefef5dc16df30c66b3 156 Pfam PF00072 Response regulator receiver domain 22 135 2.9E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_23895 df645c78d01cffefef5dc16df30c66b3 156 SUPERFAMILY SSF52172 18 140 9.82E-37 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_23895 df645c78d01cffefef5dc16df30c66b3 156 Gene3D G3DSA:3.40.50.12740 18 154 1.9E-40 T 14-10-2018 TSH58p_02005 cbd765b9f52acd8300c9c0cf7adc76c8 346 SMART SM00849 41 258 1.7E-20 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_02005 cbd765b9f52acd8300c9c0cf7adc76c8 346 SUPERFAMILY SSF56281 10 340 1.83E-63 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_02005 cbd765b9f52acd8300c9c0cf7adc76c8 346 Pfam PF00753 Metallo-beta-lactamase superfamily 40 241 5.0E-20 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_02005 cbd765b9f52acd8300c9c0cf7adc76c8 346 Gene3D G3DSA:3.60.15.10 21 285 3.7E-50 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_02005 cbd765b9f52acd8300c9c0cf7adc76c8 346 Gene3D G3DSA:1.10.10.10 292 337 9.1E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_03725 df2fce03b4d45481593bb38a956e4a6c 91 Pfam PF09956 Uncharacterized conserved protein (DUF2190) 20 83 3.6E-14 T 14-10-2018 IPR011231 Bacteriophage VT1-Sakai, H0018 TSH58p_03725 df2fce03b4d45481593bb38a956e4a6c 91 PIRSF PIRSF030771 6 85 1.3E-10 T 14-10-2018 IPR011231 Bacteriophage VT1-Sakai, H0018 TSH58p_20970 60ece93f904c80d5a5fcc872b7b6a7a4 111 Gene3D G3DSA:1.10.10.10 1 93 1.2E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_20970 60ece93f904c80d5a5fcc872b7b6a7a4 111 SMART SM00418 8 88 4.9E-14 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSH58p_20970 60ece93f904c80d5a5fcc872b7b6a7a4 111 SUPERFAMILY SSF46785 3 94 1.6E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_20970 60ece93f904c80d5a5fcc872b7b6a7a4 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 1.6E-7 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSH58p_20970 60ece93f904c80d5a5fcc872b7b6a7a4 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 1.6E-7 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSH58p_20970 60ece93f904c80d5a5fcc872b7b6a7a4 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 1.6E-7 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSH58p_20970 60ece93f904c80d5a5fcc872b7b6a7a4 111 Pfam PF12840 Helix-turn-helix domain 11 69 6.6E-12 T 14-10-2018 TSH58p_16815 5d6b3e6a5cddb33a21dd39d6b799c5f6 523 Pfam PF00672 HAMP domain 175 224 2.0E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_16815 5d6b3e6a5cddb33a21dd39d6b799c5f6 523 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 340 493 1.7E-29 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_16815 5d6b3e6a5cddb33a21dd39d6b799c5f6 523 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 115 505 0.001 T 14-10-2018 TSH58p_16815 5d6b3e6a5cddb33a21dd39d6b799c5f6 523 Gene3D G3DSA:1.10.8.500 174 225 3.5E-14 T 14-10-2018 TSH58p_16815 5d6b3e6a5cddb33a21dd39d6b799c5f6 523 Gene3D G3DSA:1.10.287.950 234 523 9.0E-50 T 14-10-2018 TSH58p_16815 5d6b3e6a5cddb33a21dd39d6b799c5f6 523 SMART SM00304 255 329 61.0 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_16815 5d6b3e6a5cddb33a21dd39d6b799c5f6 523 SMART SM00304 174 227 7.8E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSH58p_16815 5d6b3e6a5cddb33a21dd39d6b799c5f6 523 SUPERFAMILY SSF58104 202 516 2.49E-55 T 14-10-2018 TSH58p_16815 5d6b3e6a5cddb33a21dd39d6b799c5f6 523 SMART SM00283 263 517 7.2E-37 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_27305 f400e35d3c6e1293ce78745daab2636b 213 Pfam PF08239 Bacterial SH3 domain 40 90 1.7E-9 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type TSH58p_27305 f400e35d3c6e1293ce78745daab2636b 213 SMART SM00287 30 93 0.0013 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type TSH58p_27305 f400e35d3c6e1293ce78745daab2636b 213 Gene3D G3DSA:2.30.30.40 25 94 8.1E-12 T 14-10-2018 TSH58p_18880 8d1db8066f44f006862b0c09507c67f9 398 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 91 294 3.2E-34 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain TSH58p_18880 8d1db8066f44f006862b0c09507c67f9 398 Gene3D G3DSA:1.10.287.470 128 187 2.9E-76 T 14-10-2018 TSH58p_18880 8d1db8066f44f006862b0c09507c67f9 398 SUPERFAMILY SSF111369 83 299 4.05E-47 T 14-10-2018 TSH58p_18880 8d1db8066f44f006862b0c09507c67f9 398 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 69 383 3.5E-74 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 TSH58p_18880 8d1db8066f44f006862b0c09507c67f9 398 Gene3D G3DSA:2.40.30.170 80 304 2.9E-76 T 14-10-2018 TSH58p_18880 8d1db8066f44f006862b0c09507c67f9 398 Gene3D G3DSA:2.40.420.20 305 381 2.9E-76 T 14-10-2018 TSH58p_18880 8d1db8066f44f006862b0c09507c67f9 398 Gene3D G3DSA:2.40.50.100 93 221 2.9E-76 T 14-10-2018 TSH58p_16470 9e115200141c04ccc6f1756ddb4681bb 151 Pfam PF16998 17 kDa outer membrane surface antigen 68 149 3.7E-12 T 14-10-2018 IPR032635 Surface antigen domain TSH58p_16385 d8cbca3517e3ff1529a916c01041c629 154 Pfam PF11164 Protein of unknown function (DUF2948) 6 148 1.2E-47 T 14-10-2018 IPR021335 Protein of unknown function DUF2948 TSH58p_24875 75430667352be1a9471bb2f63d757e4d 309 Pfam PF00535 Glycosyl transferase family 2 8 102 1.0E-27 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_24875 75430667352be1a9471bb2f63d757e4d 309 Gene3D G3DSA:3.90.550.10 1 238 2.3E-34 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_24875 75430667352be1a9471bb2f63d757e4d 309 SUPERFAMILY SSF53448 6 223 2.72E-39 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_31650 45a5fa9087a28d1e2506e29a5fe1a112 357 SUPERFAMILY SSF53850 42 264 2.47E-31 T 14-10-2018 TSH58p_31650 45a5fa9087a28d1e2506e29a5fe1a112 357 Gene3D G3DSA:3.40.190.10 123 220 2.3E-34 T 14-10-2018 TSH58p_31650 45a5fa9087a28d1e2506e29a5fe1a112 357 Gene3D G3DSA:3.40.190.10 74 326 2.3E-34 T 14-10-2018 TSH58p_31650 45a5fa9087a28d1e2506e29a5fe1a112 357 Pfam PF09084 NMT1/THI5 like 70 256 3.2E-13 T 14-10-2018 IPR015168 SsuA/THI5-like TSH58p_31295 9b228ba7292bd5cdfdcacaa49bec235c 190 SUPERFAMILY SSF49764 53 187 2.41E-37 T 14-10-2018 IPR008978 HSP20-like chaperone TSH58p_31295 9b228ba7292bd5cdfdcacaa49bec235c 190 Pfam PF00011 Hsp20/alpha crystallin family 87 187 5.1E-25 T 14-10-2018 IPR002068 Alpha crystallin/Hsp20 domain TSH58p_31295 9b228ba7292bd5cdfdcacaa49bec235c 190 Gene3D G3DSA:2.60.40.790 38 188 4.7E-37 T 14-10-2018 IPR008978 HSP20-like chaperone TSH58p_17110 35bc0e2e6b9bfd87c7b36e3e88ad8672 235 Pfam PF00027 Cyclic nucleotide-binding domain 34 120 2.2E-13 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_17110 35bc0e2e6b9bfd87c7b36e3e88ad8672 235 SUPERFAMILY SSF46785 152 229 1.04E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_17110 35bc0e2e6b9bfd87c7b36e3e88ad8672 235 SMART SM00419 173 220 9.3E-7 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_17110 35bc0e2e6b9bfd87c7b36e3e88ad8672 235 SMART SM00100 15 137 1.7E-9 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_17110 35bc0e2e6b9bfd87c7b36e3e88ad8672 235 Pfam PF13545 Crp-like helix-turn-helix domain 155 227 9.8E-12 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSH58p_17110 35bc0e2e6b9bfd87c7b36e3e88ad8672 235 Gene3D G3DSA:1.10.10.10 152 232 3.2E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_17110 35bc0e2e6b9bfd87c7b36e3e88ad8672 235 SUPERFAMILY SSF51206 10 148 3.14E-26 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like TSH58p_17110 35bc0e2e6b9bfd87c7b36e3e88ad8672 235 Gene3D G3DSA:2.60.120.10 8 151 1.8E-28 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_09650 97b773f316f90173d310921a3b205e05 156 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 18 136 1.5E-14 T 14-10-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component TSH58p_09650 97b773f316f90173d310921a3b205e05 156 SMART SM00670 17 136 0.0029 T 14-10-2018 IPR002716 PIN domain TSH58p_09650 97b773f316f90173d310921a3b205e05 156 SUPERFAMILY SSF88723 18 140 9.81E-14 T 14-10-2018 IPR029060 PIN-like domain superfamily TSH58p_09650 97b773f316f90173d310921a3b205e05 156 Pfam PF13470 PIN domain 18 132 1.3E-18 T 14-10-2018 IPR002716 PIN domain TSH58p_08550 6f998e42f77ef135dcfd687eea376033 409 Gene3D G3DSA:3.40.710.10 27 406 7.7E-122 T 14-10-2018 TSH58p_08550 6f998e42f77ef135dcfd687eea376033 409 Pfam PF00144 Beta-lactamase 41 390 7.7E-73 T 14-10-2018 IPR001466 Beta-lactamase-related TSH58p_08550 6f998e42f77ef135dcfd687eea376033 409 SUPERFAMILY SSF56601 36 404 4.88E-96 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TSH58p_20725 2b9eb6f6b9408c337e802671273d1348 235 Pfam PF09476 Pilus biogenesis CpaD protein (pilus_cpaD) 29 207 1.1E-28 T 14-10-2018 IPR019027 Pilus biogenesis CpaD-related TSH58p_06335 42934ec22793e84e803c304438ebb90a 259 SUPERFAMILY SSF52172 137 250 2.42E-24 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_06335 42934ec22793e84e803c304438ebb90a 259 SUPERFAMILY SSF88659 80 134 2.62E-8 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSH58p_06335 42934ec22793e84e803c304438ebb90a 259 Gene3D G3DSA:1.20.140.160 3 134 7.5E-33 T 14-10-2018 TSH58p_06335 42934ec22793e84e803c304438ebb90a 259 Gene3D G3DSA:3.40.50.2300 135 254 3.9E-31 T 14-10-2018 TSH58p_06335 42934ec22793e84e803c304438ebb90a 259 Pfam PF00072 Response regulator receiver domain 138 246 3.3E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_06335 42934ec22793e84e803c304438ebb90a 259 Pfam PF08281 Sigma-70, region 4 80 127 4.4E-8 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_06335 42934ec22793e84e803c304438ebb90a 259 SMART SM00448 136 246 1.1E-19 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_15910 24b4ca5ab21572316666e314044801b9 378 Pfam PF13088 BNR repeat-like domain 145 355 3.8E-17 T 14-10-2018 IPR011040 Sialidase KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 TSH58p_15910 24b4ca5ab21572316666e314044801b9 378 SUPERFAMILY SSF50939 86 367 1.4E-28 T 14-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 TSH58p_15910 24b4ca5ab21572316666e314044801b9 378 Gene3D G3DSA:2.120.10.10 1 377 2.9E-104 T 14-10-2018 TSH58p_03710 b01010d256e528b22a296af942a25c4e 292 Pfam PF00892 EamA-like transporter family 7 136 1.2E-7 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_03710 b01010d256e528b22a296af942a25c4e 292 Pfam PF00892 EamA-like transporter family 156 284 2.8E-8 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_03710 b01010d256e528b22a296af942a25c4e 292 SUPERFAMILY SSF103481 196 288 1.06E-10 T 14-10-2018 TSH58p_03710 b01010d256e528b22a296af942a25c4e 292 SUPERFAMILY SSF103481 42 140 9.42E-11 T 14-10-2018 TSH58p_14895 ca2c26c6c6f02276190030d0d7c5e5c6 238 Pfam PF00440 Bacterial regulatory proteins, tetR family 46 92 4.7E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_14895 ca2c26c6c6f02276190030d0d7c5e5c6 238 Gene3D G3DSA:1.10.357.10 42 238 7.8E-59 T 14-10-2018 TSH58p_14895 ca2c26c6c6f02276190030d0d7c5e5c6 238 SUPERFAMILY SSF46689 34 114 1.64E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_14895 ca2c26c6c6f02276190030d0d7c5e5c6 238 SUPERFAMILY SSF48498 112 237 1.28E-34 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TSH58p_14895 ca2c26c6c6f02276190030d0d7c5e5c6 238 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 67 90 7.1E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_14895 ca2c26c6c6f02276190030d0d7c5e5c6 238 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 59 7.1E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_14895 ca2c26c6c6f02276190030d0d7c5e5c6 238 Pfam PF14514 Transcriptional regulator, TetR, C-terminal 117 235 1.1E-5 T 14-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal TSH58p_13980 0e24764bd1321262a3caa88a03f12bdf 129 Pfam PF00072 Response regulator receiver domain 10 123 3.0E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_13980 0e24764bd1321262a3caa88a03f12bdf 129 SMART SM00448 8 124 5.0E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_13980 0e24764bd1321262a3caa88a03f12bdf 129 Gene3D G3DSA:3.40.50.2300 4 128 1.5E-32 T 14-10-2018 TSH58p_13980 0e24764bd1321262a3caa88a03f12bdf 129 SUPERFAMILY SSF52172 7 128 9.68E-34 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_22740 6b2101736f0580295150d38631015c86 67 Pfam PF01381 Helix-turn-helix 7 50 7.3E-8 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_22740 6b2101736f0580295150d38631015c86 67 SUPERFAMILY SSF47413 1 56 1.36E-17 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_22740 6b2101736f0580295150d38631015c86 67 Gene3D G3DSA:1.10.260.40 1 63 4.8E-19 T 14-10-2018 TSH58p_20105 17dba8bb0807cc72af77cfeb97898b6c 316 Gene3D G3DSA:3.30.1330.60 154 316 2.7E-43 T 14-10-2018 IPR036737 OmpA-like domain superfamily TSH58p_20105 17dba8bb0807cc72af77cfeb97898b6c 316 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 17 64 1.0E-16 T 14-10-2018 IPR025713 Motility protein B, N-terminal domain TSH58p_20105 17dba8bb0807cc72af77cfeb97898b6c 316 SUPERFAMILY SSF103088 205 309 2.49E-18 T 14-10-2018 IPR036737 OmpA-like domain superfamily TSH58p_20105 17dba8bb0807cc72af77cfeb97898b6c 316 Pfam PF00691 OmpA family 207 296 2.2E-12 T 14-10-2018 IPR006665 OmpA-like domain TSH58p_09915 f896485d8addf57e685e3e0e042d491c 60 Pfam PF07896 Protein of unknown function (DUF1674) 15 60 6.6E-15 T 14-10-2018 IPR012875 Protein of unknown function DUF1674 TSH58p_21820 2c7269f22846cfafcbe69828e38fa678 832 Gene3D G3DSA:3.40.50.2000 30 821 0.0 T 14-10-2018 TSH58p_21820 2c7269f22846cfafcbe69828e38fa678 832 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 662 674 - T 14-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TSH58p_21820 2c7269f22846cfafcbe69828e38fa678 832 PIRSF PIRSF000460 7 831 7.2E-241 T 14-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TSH58p_21820 2c7269f22846cfafcbe69828e38fa678 832 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 18 819 0.0 T 14-10-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TSH58p_21820 2c7269f22846cfafcbe69828e38fa678 832 SUPERFAMILY SSF53756 14 823 0.0 T 14-10-2018 TSH58p_21820 2c7269f22846cfafcbe69828e38fa678 832 Pfam PF00343 Carbohydrate phosphorylase 106 819 0.0 T 14-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TSH58p_21820 2c7269f22846cfafcbe69828e38fa678 832 Gene3D G3DSA:3.40.50.2000 476 804 0.0 T 14-10-2018 TSH58p_00930 e6cd6786cfb2d7ecabc76557aacfa986 228 Pfam PF07484 Phage Tail Collar Domain 6 62 3.2E-17 T 14-10-2018 IPR011083 Phage tail collar domain TSH58p_00930 e6cd6786cfb2d7ecabc76557aacfa986 228 Gene3D G3DSA:3.90.1340.10 5 59 1.9E-11 T 14-10-2018 IPR037053 Phage tail collar domain superfamily TSH58p_00930 e6cd6786cfb2d7ecabc76557aacfa986 228 Gene3D G3DSA:4.10.1070.10 60 89 1.9E-11 T 14-10-2018 TSH58p_00930 e6cd6786cfb2d7ecabc76557aacfa986 228 SUPERFAMILY SSF88874 2 218 4.58E-23 T 14-10-2018 TSH58p_06985 9623e0af3163faa5e92564ccf15055bf 255 SUPERFAMILY SSF88874 28 169 1.57E-25 T 14-10-2018 TSH58p_06985 9623e0af3163faa5e92564ccf15055bf 255 Gene3D G3DSA:4.10.1070.10 86 105 1.3E-12 T 14-10-2018 TSH58p_06985 9623e0af3163faa5e92564ccf15055bf 255 Pfam PF07484 Phage Tail Collar Domain 33 88 6.7E-17 T 14-10-2018 IPR011083 Phage tail collar domain TSH58p_06985 9623e0af3163faa5e92564ccf15055bf 255 Gene3D G3DSA:3.90.1340.10 32 85 1.3E-12 T 14-10-2018 IPR037053 Phage tail collar domain superfamily TSH58p_28150 1878374d90e6de16f60113418b1ba270 162 SUPERFAMILY SSF52172 2 117 3.42E-20 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_28150 1878374d90e6de16f60113418b1ba270 162 SMART SM00448 1 110 3.9E-10 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_28150 1878374d90e6de16f60113418b1ba270 162 Pfam PF00072 Response regulator receiver domain 4 110 1.3E-11 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_28150 1878374d90e6de16f60113418b1ba270 162 Gene3D G3DSA:3.40.50.2300 1 117 2.0E-26 T 14-10-2018 TSH58p_23120 1b8cf2887ace0de5c84422381d4f2662 558 PRINTS PR00344 Bacterial sensor protein C-terminal signature 491 505 3.6E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_23120 1b8cf2887ace0de5c84422381d4f2662 558 PRINTS PR00344 Bacterial sensor protein C-terminal signature 509 519 3.6E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_23120 1b8cf2887ace0de5c84422381d4f2662 558 PRINTS PR00344 Bacterial sensor protein C-terminal signature 520 538 3.6E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_23120 1b8cf2887ace0de5c84422381d4f2662 558 Gene3D G3DSA:3.30.565.10 431 558 1.7E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_23120 1b8cf2887ace0de5c84422381d4f2662 558 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 458 557 3.3E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_23120 1b8cf2887ace0de5c84422381d4f2662 558 SUPERFAMILY SSF55874 417 557 7.99E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_23120 1b8cf2887ace0de5c84422381d4f2662 558 SUPERFAMILY SSF47384 364 423 1.49E-8 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_23120 1b8cf2887ace0de5c84422381d4f2662 558 SMART SM00388 370 427 0.0034 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_23120 1b8cf2887ace0de5c84422381d4f2662 558 SMART SM00387 457 558 1.0E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_23120 1b8cf2887ace0de5c84422381d4f2662 558 Gene3D G3DSA:1.10.287.130 358 424 5.7E-8 T 14-10-2018 TSH58p_04720 7d6d57166cc7ebefb6128bd3c6769fbd 96 Pfam PF03692 Putative zinc- or iron-chelating domain 9 80 5.2E-9 T 14-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein TSH58p_32430 7b34ae0ebffc4a515bf41e12b98d12f3 477 Gene3D G3DSA:1.10.760.10 329 477 2.5E-7 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_32430 7b34ae0ebffc4a515bf41e12b98d12f3 477 PIRSF PIRSF028099 10 81 4.7 T 14-10-2018 IPR010538 Di-haem oxidoreductase, putative peroxidase TSH58p_32430 7b34ae0ebffc4a515bf41e12b98d12f3 477 PIRSF PIRSF028099 70 477 3.8E-143 T 14-10-2018 IPR010538 Di-haem oxidoreductase, putative peroxidase TSH58p_32430 7b34ae0ebffc4a515bf41e12b98d12f3 477 Pfam PF06537 Di-haem oxidoreductase, putative peroxidase 96 477 3.1E-105 T 14-10-2018 IPR010538 Di-haem oxidoreductase, putative peroxidase TSH58p_32430 7b34ae0ebffc4a515bf41e12b98d12f3 477 SUPERFAMILY SSF46626 333 477 3.24E-24 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_27810 aa590244c590118053b67b1fd024551c 383 SUPERFAMILY SSF103473 2 381 4.32E-53 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_27810 aa590244c590118053b67b1fd024551c 383 Pfam PF07690 Major Facilitator Superfamily 9 322 3.2E-36 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_27810 aa590244c590118053b67b1fd024551c 383 Gene3D G3DSA:1.20.1250.20 2 377 9.3E-52 T 14-10-2018 TSH58p_12175 8bb0f99a97b87e4853543211bdccf01d 100 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 2 95 20.133 T 14-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 TSH58p_12175 8bb0f99a97b87e4853543211bdccf01d 100 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 6 94 3.0E-26 T 14-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 TSH58p_12175 8bb0f99a97b87e4853543211bdccf01d 100 Gene3D G3DSA:3.30.1360.20 1 97 3.2E-31 T 14-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 TSH58p_12175 8bb0f99a97b87e4853543211bdccf01d 100 SUPERFAMILY SSF55248 2 95 9.42E-29 T 14-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 TSH58p_06490 317f0c7d7c6f29a03dd25ff24087cab7 289 PIRSF PIRSF038471 14 288 1.4E-63 T 14-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 TSH58p_06490 317f0c7d7c6f29a03dd25ff24087cab7 289 Gene3D G3DSA:2.40.10.350 191 261 9.2E-32 T 14-10-2018 TSH58p_06490 317f0c7d7c6f29a03dd25ff24087cab7 289 Gene3D G3DSA:2.40.10.340 132 270 9.2E-32 T 14-10-2018 TSH58p_06490 317f0c7d7c6f29a03dd25ff24087cab7 289 Pfam PF04085 rod shape-determining protein MreC 134 273 6.6E-34 T 14-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 TSH58p_06490 317f0c7d7c6f29a03dd25ff24087cab7 289 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 19 274 1.8E-39 T 14-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 TSH58p_28005 ca16910824fa0ba8200f2d4d3946a0f1 240 Pfam PF02397 Bacterial sugar transferase 44 234 6.1E-61 T 14-10-2018 IPR003362 Bacterial sugar transferase TSH58p_29115 11fa26f35fa59b2d1a68d0eacf427d98 220 SUPERFAMILY SSF159594 30 201 9.42E-39 T 14-10-2018 TSH58p_29115 11fa26f35fa59b2d1a68d0eacf427d98 220 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 32 192 8.1E-18 T 14-10-2018 IPR005586 ABC-type transport auxiliary lipoprotein component TSH58p_29115 11fa26f35fa59b2d1a68d0eacf427d98 220 Gene3D G3DSA:3.40.50.10610 23 209 9.7E-58 T 14-10-2018 TSH58p_18140 5e0c15edcea341759a8c441b71b3662d 356 SUPERFAMILY SSF51735 3 347 5.18E-63 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_18140 5e0c15edcea341759a8c441b71b3662d 356 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 278 2.5E-36 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TSH58p_18140 5e0c15edcea341759a8c441b71b3662d 356 Gene3D G3DSA:3.90.25.10 214 345 6.0E-64 T 14-10-2018 TSH58p_18140 5e0c15edcea341759a8c441b71b3662d 356 Gene3D G3DSA:3.40.50.720 4 278 6.0E-64 T 14-10-2018 TSH58p_01895 2de9731d4d0baaf770908fd69b1d24c1 257 Pfam PF01435 Peptidase family M48 65 245 3.6E-38 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 TSH58p_20395 832a9eb1b0f905349c11483961dbfd87 219 TIGRFAM TIGR01848 PHA_reg_PhaR: polyhydroxyalkanoate synthesis repressor PhaR 14 117 5.0E-46 T 14-10-2018 IPR010134 Polyhydroxyalkanoate synthesis repressor PhaR GO:0006355 TSH58p_20395 832a9eb1b0f905349c11483961dbfd87 219 Pfam PF05233 PHB accumulation regulatory domain 77 116 6.2E-18 T 14-10-2018 IPR007897 PHB accumulation regulatory TSH58p_20395 832a9eb1b0f905349c11483961dbfd87 219 Pfam PF07879 PHB/PHA accumulation regulator DNA-binding domain 13 73 3.2E-30 T 14-10-2018 IPR012909 PHA accumulation regulator DNA-binding, N-terminal TSH58p_31340 3bd487f0d32f649168965cb2f5c05cce 304 SUPERFAMILY SSF51430 32 294 7.86E-49 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TSH58p_31340 3bd487f0d32f649168965cb2f5c05cce 304 Gene3D G3DSA:3.20.20.100 31 300 1.3E-41 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TSH58p_31340 3bd487f0d32f649168965cb2f5c05cce 304 Pfam PF00248 Aldo/keto reductase family 45 294 2.1E-26 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain TSH58p_31325 b5a1397b99fe14e98e1b575c1bdd3c59 426 SUPERFAMILY SSF111369 77 326 1.7E-22 T 14-10-2018 TSH58p_31325 b5a1397b99fe14e98e1b575c1bdd3c59 426 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 77 322 5.5E-17 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain TSH58p_31325 b5a1397b99fe14e98e1b575c1bdd3c59 426 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 75 343 2.0E-41 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 TSH58p_31325 b5a1397b99fe14e98e1b575c1bdd3c59 426 Gene3D G3DSA:2.40.420.20 71 420 4.2E-67 T 14-10-2018 TSH58p_31325 b5a1397b99fe14e98e1b575c1bdd3c59 426 Gene3D G3DSA:2.40.50.100 87 250 4.2E-67 T 14-10-2018 TSH58p_31325 b5a1397b99fe14e98e1b575c1bdd3c59 426 Gene3D G3DSA:1.10.287.470 121 212 4.2E-67 T 14-10-2018 TSH58p_31325 b5a1397b99fe14e98e1b575c1bdd3c59 426 Gene3D G3DSA:2.40.30.170 76 329 4.2E-67 T 14-10-2018 TSH58p_14025 9a6d95e51d3a6955dc4223ee17fd0610 156 Pfam PF00210 Ferritin-like domain 11 153 3.0E-6 T 14-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 TSH58p_14025 9a6d95e51d3a6955dc4223ee17fd0610 156 Gene3D G3DSA:1.20.1260.10 5 153 6.2E-52 T 14-10-2018 IPR012347 Ferritin-like TSH58p_14025 9a6d95e51d3a6955dc4223ee17fd0610 156 SUPERFAMILY SSF47240 10 153 2.4E-29 T 14-10-2018 IPR009078 Ferritin-like superfamily TSH58p_28075 1868d14952ea8d0b26dc315499b1f8b9 568 SUPERFAMILY SSF56762 1 553 6.28E-167 T 14-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_28075 1868d14952ea8d0b26dc315499b1f8b9 568 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 544 553 - T 14-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 TSH58p_28075 1868d14952ea8d0b26dc315499b1f8b9 568 Pfam PF00374 Nickel-dependent hydrogenase 39 553 2.9E-213 T 14-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 TSH58p_28075 1868d14952ea8d0b26dc315499b1f8b9 568 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 39 64 - T 14-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 TSH58p_28075 1868d14952ea8d0b26dc315499b1f8b9 568 Gene3D G3DSA:1.10.645.10 1 553 1.9E-220 T 14-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_15650 d6ecf896bc7f21eacccc9ba6ffb75fc7 232 Pfam PF02666 Phosphatidylserine decarboxylase 45 216 1.5E-29 T 14-10-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 TSH58p_15650 d6ecf896bc7f21eacccc9ba6ffb75fc7 232 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 10 220 37.88 T 14-10-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 TSH58p_15650 d6ecf896bc7f21eacccc9ba6ffb75fc7 232 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 11 222 5.5E-54 T 14-10-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 TSH58p_13575 f83e090bb6c315bc0653536bdd1dcd73 254 Hamap MF_00560 Trans-aconitate 2-methyltransferase [tam]. 1 254 40.725 T 14-10-2018 IPR023506 Trans-aconitate 2-methyltransferase GO:0030798 TSH58p_13575 f83e090bb6c315bc0653536bdd1dcd73 254 Gene3D G3DSA:1.10.150.290 131 235 5.3E-86 T 14-10-2018 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 TSH58p_13575 f83e090bb6c315bc0653536bdd1dcd73 254 Pfam PF13649 Methyltransferase domain 34 123 1.7E-16 T 14-10-2018 TSH58p_13575 f83e090bb6c315bc0653536bdd1dcd73 254 SUPERFAMILY SSF53335 3 201 2.15E-32 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_13575 f83e090bb6c315bc0653536bdd1dcd73 254 Gene3D G3DSA:3.40.50.150 8 252 5.3E-86 T 14-10-2018 TSH58p_11035 71e2ef046580134c9253c542ed25d02e 672 SUPERFAMILY SSF48208 190 527 8.17E-72 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TSH58p_11035 71e2ef046580134c9253c542ed25d02e 672 Gene3D G3DSA:1.50.10.10 408 575 3.3E-13 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 TSH58p_11035 71e2ef046580134c9253c542ed25d02e 672 Gene3D G3DSA:3.40.30.10 2 173 2.0E-65 T 14-10-2018 TSH58p_11035 71e2ef046580134c9253c542ed25d02e 672 Pfam PF03190 Protein of unknown function, DUF255 4 164 3.5E-72 T 14-10-2018 IPR004879 Domain of unknown function DUF255 TSH58p_11035 71e2ef046580134c9253c542ed25d02e 672 SUPERFAMILY SSF52833 3 130 2.61E-30 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_11035 71e2ef046580134c9253c542ed25d02e 672 PIRSF PIRSF006402 1 672 6.0E-214 T 14-10-2018 IPR024705 Spermatogenesis-associated protein 20 TSH58p_32620 211a542f13e796905b12dfddbca80726 330 Pfam PF16220 Domain of unknown function (DUF4880) 14 56 1.1E-13 T 14-10-2018 IPR032623 FecR, N-terminal TSH58p_32620 211a542f13e796905b12dfddbca80726 330 Pfam PF04773 FecR protein 128 212 7.1E-18 T 14-10-2018 IPR006860 FecR protein TSH58p_32620 211a542f13e796905b12dfddbca80726 330 Gene3D G3DSA:2.60.120.1440 120 252 2.8E-26 T 14-10-2018 TSH58p_32620 211a542f13e796905b12dfddbca80726 330 PIRSF PIRSF018266 3 330 1.5E-79 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component TSH58p_03940 d6e7035e21890a640fda250d942aad83 225 Gene3D G3DSA:1.10.10.10 7 210 1.9E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_03940 d6e7035e21890a640fda250d942aad83 225 SMART SM00421 138 195 1.3E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_03940 d6e7035e21890a640fda250d942aad83 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 171 2.9E-6 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_03940 d6e7035e21890a640fda250d942aad83 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 183 2.9E-6 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_03940 d6e7035e21890a640fda250d942aad83 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 141 155 2.9E-6 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_03940 d6e7035e21890a640fda250d942aad83 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 194 1.8E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_03940 d6e7035e21890a640fda250d942aad83 225 SUPERFAMILY SSF46894 123 198 1.33E-14 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_05565 751422b4dcb7a36314a356dfa62e0113 148 SUPERFAMILY SSF81585 68 132 1.18E-15 T 14-10-2018 TSH58p_05565 751422b4dcb7a36314a356dfa62e0113 148 Pfam PF12836 Helix-hairpin-helix motif 72 130 2.8E-13 T 14-10-2018 TSH58p_05565 751422b4dcb7a36314a356dfa62e0113 148 Gene3D G3DSA:1.10.150.320 59 130 1.5E-14 T 14-10-2018 TSH58p_28225 4fe4f64be95bcb5388b46fa3274daf55 290 Gene3D G3DSA:3.30.470.10 5 130 1.1E-41 T 14-10-2018 TSH58p_28225 4fe4f64be95bcb5388b46fa3274daf55 290 Pfam PF01063 Amino-transferase class IV 40 266 1.3E-48 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 TSH58p_28225 4fe4f64be95bcb5388b46fa3274daf55 290 Gene3D G3DSA:3.20.10.10 133 290 2.1E-44 T 14-10-2018 TSH58p_28225 4fe4f64be95bcb5388b46fa3274daf55 290 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 14 289 1.2E-85 T 14-10-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 TSH58p_28225 4fe4f64be95bcb5388b46fa3274daf55 290 SUPERFAMILY SSF56752 6 290 1.44E-89 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 TSH58p_28225 4fe4f64be95bcb5388b46fa3274daf55 290 ProSitePatterns PS00770 Aminotransferases class-IV signature. 193 221 - T 14-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 TSH58p_30515 b16040ae68fe3dba2383dd1acd02aae0 346 PIRSF PIRSF006470 6 344 1.8E-84 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 TSH58p_30515 b16040ae68fe3dba2383dd1acd02aae0 346 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 50 276 4.4E-61 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 TSH58p_30515 b16040ae68fe3dba2383dd1acd02aae0 346 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 47 326 2.5E-72 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 TSH58p_30515 b16040ae68fe3dba2383dd1acd02aae0 346 Gene3D G3DSA:3.40.190.170 32 345 3.2E-110 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily TSH58p_17090 94fa2435f7571672339fba2a15bc5a21 241 Pfam PF04367 Protein of unknown function (DUF502) 85 187 1.7E-33 T 14-10-2018 IPR007462 Protein of unknown function DUF502 TSH58p_02255 94cd7289c1ea3cd0c9aece2ac49269f8 217 Gene3D G3DSA:3.40.50.850 10 213 4.3E-63 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TSH58p_02255 94cd7289c1ea3cd0c9aece2ac49269f8 217 SUPERFAMILY SSF52499 18 210 7.33E-47 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TSH58p_02255 94cd7289c1ea3cd0c9aece2ac49269f8 217 Pfam PF00857 Isochorismatase family 27 201 9.2E-33 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 TSH58p_17535 60af945710ce4f3ed6382cf20cdc56b7 166 Gene3D G3DSA:3.40.630.30 3 163 9.8E-20 T 14-10-2018 TSH58p_17535 60af945710ce4f3ed6382cf20cdc56b7 166 SUPERFAMILY SSF55729 5 144 9.78E-20 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_17535 60af945710ce4f3ed6382cf20cdc56b7 166 Pfam PF00583 Acetyltransferase (GNAT) family 58 131 2.0E-6 T 14-10-2018 IPR000182 GNAT domain TSH58p_11100 33d613fb6745374a3b7fb32459e1670f 205 Pfam PF04186 FxsA cytoplasmic membrane protein 6 111 2.5E-33 T 14-10-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 TSH58p_14940 d563d15ba653e2d585cbfcaa2febc011 534 Pfam PF02653 Branched-chain amino acid transport system / permease component 244 516 5.0E-53 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_14940 d563d15ba653e2d585cbfcaa2febc011 534 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 240 530 3.2E-128 T 14-10-2018 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type TSH58p_21580 2f118154e47bed0c6d2755355684563f 513 Pfam PF00374 Nickel-dependent hydrogenase 191 257 6.4E-10 T 14-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 TSH58p_21580 2f118154e47bed0c6d2755355684563f 513 SUPERFAMILY SSF56762 163 512 6.93E-102 T 14-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_21580 2f118154e47bed0c6d2755355684563f 513 Gene3D G3DSA:1.10.645.20 154 512 2.9E-109 T 14-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_21580 2f118154e47bed0c6d2755355684563f 513 SUPERFAMILY SSF143243 34 167 3.01E-18 T 14-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_21580 2f118154e47bed0c6d2755355684563f 513 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 75 129 1.7E-7 T 14-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_21580 2f118154e47bed0c6d2755355684563f 513 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 276 426 3.3E-33 T 14-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_21580 2f118154e47bed0c6d2755355684563f 513 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 444 509 7.5E-6 T 14-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_00665 7d8aac83320077ee60adb408130caec9 140 SMART SM00448 3 115 6.7E-12 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_00665 7d8aac83320077ee60adb408130caec9 140 Pfam PF00072 Response regulator receiver domain 5 112 2.4E-17 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_00665 7d8aac83320077ee60adb408130caec9 140 Gene3D G3DSA:3.40.50.2300 2 132 1.8E-21 T 14-10-2018 TSH58p_00665 7d8aac83320077ee60adb408130caec9 140 SUPERFAMILY SSF52172 3 118 2.56E-22 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_20960 66d3346028faa9a6e2d3c3d12e044c27 423 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 7 417 2.0E-92 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TSH58p_20960 66d3346028faa9a6e2d3c3d12e044c27 423 PIRSF PIRSF006066 1 423 1.6E-103 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSH58p_20960 66d3346028faa9a6e2d3c3d12e044c27 423 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 421 2.6E-96 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSH58p_20950 55e2ad8d9e6bd306ef26c57cb96f4477 462 ProSitePatterns PS00571 Amidases signature. 154 185 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 TSH58p_20950 55e2ad8d9e6bd306ef26c57cb96f4477 462 SUPERFAMILY SSF75304 3 456 1.44E-131 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_20950 55e2ad8d9e6bd306ef26c57cb96f4477 462 Gene3D G3DSA:3.90.1300.10 7 450 8.7E-138 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_20950 55e2ad8d9e6bd306ef26c57cb96f4477 462 Pfam PF01425 Amidase 27 439 2.0E-107 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_30725 cf25fd05a556ab294a71371a8188c925 336 SMART SM00382 40 253 2.0E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_30725 cf25fd05a556ab294a71371a8188c925 336 SUPERFAMILY SSF52540 40 311 1.3E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_30725 cf25fd05a556ab294a71371a8188c925 336 Pfam PF00005 ABC transporter 31 189 4.4E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_30725 cf25fd05a556ab294a71371a8188c925 336 Gene3D G3DSA:3.40.50.300 5 332 1.6E-89 T 14-10-2018 TSH58p_30725 cf25fd05a556ab294a71371a8188c925 336 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 244 328 2.3E-19 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_30725 cf25fd05a556ab294a71371a8188c925 336 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 246 309 5.3E-17 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_04300 6900363c2e27870e6453b133306cea92 392 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 7 385 4.6E-105 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TSH58p_04300 6900363c2e27870e6453b133306cea92 392 SUPERFAMILY SSF53383 23 386 6.66E-95 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_04300 6900363c2e27870e6453b133306cea92 392 PIRSF PIRSF001434 1 389 1.3E-122 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TSH58p_04300 6900363c2e27870e6453b133306cea92 392 Gene3D G3DSA:3.40.640.10 1 257 3.8E-72 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_04300 6900363c2e27870e6453b133306cea92 392 Gene3D G3DSA:3.90.1150.10 258 389 2.4E-35 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_04300 6900363c2e27870e6453b133306cea92 392 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 8 387 2.6E-142 T 14-10-2018 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8 TSH58p_05260 2b41c4bfbb3a118d09e59ef05f6c7393 448 Pfam PF07690 Major Facilitator Superfamily 25 365 3.2E-41 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_05260 2b41c4bfbb3a118d09e59ef05f6c7393 448 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 18 394 4.0E-76 T 14-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 TSH58p_05260 2b41c4bfbb3a118d09e59ef05f6c7393 448 SUPERFAMILY SSF103473 16 399 2.49E-61 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_05260 2b41c4bfbb3a118d09e59ef05f6c7393 448 Gene3D G3DSA:1.20.1720.10 19 397 4.8E-88 T 14-10-2018 TSH58p_05720 6d7a224ced8a6047491354b18fd1dbe1 156 Gene3D G3DSA:3.10.129.10 3 156 3.0E-62 T 14-10-2018 TSH58p_05720 6d7a224ced8a6047491354b18fd1dbe1 156 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 13 151 2.7E-58 T 14-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 TSH58p_05720 6d7a224ced8a6047491354b18fd1dbe1 156 Pfam PF07977 FabA-like domain 22 146 2.2E-38 T 14-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 TSH58p_05720 6d7a224ced8a6047491354b18fd1dbe1 156 SUPERFAMILY SSF54637 13 152 4.67E-49 T 14-10-2018 IPR029069 HotDog domain superfamily TSH58p_05720 6d7a224ced8a6047491354b18fd1dbe1 156 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 13 154 34.45 T 14-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 TSH58p_26090 b04435f58110209e0565346f73b21e2d 224 Pfam PF08238 Sel1 repeat 52 86 3.8E-7 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_26090 b04435f58110209e0565346f73b21e2d 224 Pfam PF08238 Sel1 repeat 35 50 0.77 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_26090 b04435f58110209e0565346f73b21e2d 224 Pfam PF08238 Sel1 repeat 175 187 47.0 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_26090 b04435f58110209e0565346f73b21e2d 224 Pfam PF08238 Sel1 repeat 124 158 0.071 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_26090 b04435f58110209e0565346f73b21e2d 224 Pfam PF08238 Sel1 repeat 89 122 4.5E-5 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_26090 b04435f58110209e0565346f73b21e2d 224 SUPERFAMILY SSF81901 29 196 9.59E-34 T 14-10-2018 TSH58p_26090 b04435f58110209e0565346f73b21e2d 224 SMART SM00671 87 122 0.0019 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_26090 b04435f58110209e0565346f73b21e2d 224 SMART SM00671 17 50 70.0 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_26090 b04435f58110209e0565346f73b21e2d 224 SMART SM00671 51 86 5.5E-8 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_26090 b04435f58110209e0565346f73b21e2d 224 SMART SM00671 123 158 0.035 T 14-10-2018 IPR006597 Sel1-like repeat TSH58p_26090 b04435f58110209e0565346f73b21e2d 224 Gene3D G3DSA:1.25.40.10 6 220 1.4E-42 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_21650 e2d601accfd4ae408117f1bcd6d31a01 106 Pfam PF01906 Putative heavy-metal-binding 1 104 1.5E-37 T 14-10-2018 IPR002765 Uncharacterised protein family UPF0145 TSH58p_21650 e2d601accfd4ae408117f1bcd6d31a01 106 Gene3D G3DSA:3.30.110.70 2 106 3.6E-40 T 14-10-2018 TSH58p_21650 e2d601accfd4ae408117f1bcd6d31a01 106 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 105 24.306 T 14-10-2018 IPR002765 Uncharacterised protein family UPF0145 TSH58p_21650 e2d601accfd4ae408117f1bcd6d31a01 106 SUPERFAMILY SSF117782 1 105 3.14E-35 T 14-10-2018 IPR035439 UPF0145 domain superfamily TSH58p_17980 2149da5effd02822657f988b35ecc6e0 143 Pfam PF09557 Domain of unknown function (DUF2382) 22 130 1.3E-15 T 14-10-2018 IPR019060 Domain of unknown function DUF2382 TSH58p_12230 8ab42c6bff8cce3095e95dfe01432a3e 259 Gene3D G3DSA:3.90.550.10 21 254 1.3E-45 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_12230 8ab42c6bff8cce3095e95dfe01432a3e 259 Pfam PF12804 MobA-like NTP transferase domain 22 150 1.3E-16 T 14-10-2018 IPR025877 MobA-like NTP transferase TSH58p_12230 8ab42c6bff8cce3095e95dfe01432a3e 259 SUPERFAMILY SSF53448 17 249 3.83E-47 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_13805 b302df493aff28baabddb31d5c9e4f0e 388 Pfam PF13458 Periplasmic binding protein 23 360 6.5E-76 T 14-10-2018 IPR028081 Leucine-binding protein domain TSH58p_13805 b302df493aff28baabddb31d5c9e4f0e 388 SUPERFAMILY SSF53822 23 386 1.81E-88 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_13805 b302df493aff28baabddb31d5c9e4f0e 388 Gene3D G3DSA:3.40.50.2300 141 356 1.0E-101 T 14-10-2018 TSH58p_13805 b302df493aff28baabddb31d5c9e4f0e 388 Gene3D G3DSA:3.40.50.2300 25 350 1.0E-101 T 14-10-2018 TSH58p_12205 c9a2c061d63837c6a3945f3e3e61e77e 66 Pfam PF06568 Domain of unknown function (DUF1127) 21 56 5.6E-13 T 14-10-2018 IPR009506 Protein of unknown function DUF1127 TSH58p_15015 247706da842aef033e074cbd29f4f6db 418 Pfam PF13458 Periplasmic binding protein 45 386 8.6E-75 T 14-10-2018 IPR028081 Leucine-binding protein domain TSH58p_15015 247706da842aef033e074cbd29f4f6db 418 Gene3D G3DSA:3.40.50.2300 65 378 2.3E-132 T 14-10-2018 TSH58p_15015 247706da842aef033e074cbd29f4f6db 418 SUPERFAMILY SSF53822 45 402 9.13E-90 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_15015 247706da842aef033e074cbd29f4f6db 418 Gene3D G3DSA:3.40.50.2300 165 390 2.3E-132 T 14-10-2018 TSH58p_27915 2a65a3bdaebccc2696671a303d386bba 214 Pfam PF00072 Response regulator receiver domain 3 114 8.7E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_27915 2a65a3bdaebccc2696671a303d386bba 214 SMART SM00448 1 115 8.5E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_27915 2a65a3bdaebccc2696671a303d386bba 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 3.3E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_27915 2a65a3bdaebccc2696671a303d386bba 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 3.3E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_27915 2a65a3bdaebccc2696671a303d386bba 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 3.3E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_27915 2a65a3bdaebccc2696671a303d386bba 214 Gene3D G3DSA:3.40.50.2300 1 127 1.2E-27 T 14-10-2018 TSH58p_27915 2a65a3bdaebccc2696671a303d386bba 214 SUPERFAMILY SSF52172 1 129 1.22E-25 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_27915 2a65a3bdaebccc2696671a303d386bba 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 206 3.5E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_27915 2a65a3bdaebccc2696671a303d386bba 214 SUPERFAMILY SSF46894 144 208 2.65E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_27915 2a65a3bdaebccc2696671a303d386bba 214 Gene3D G3DSA:1.10.10.10 142 213 3.1E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_27915 2a65a3bdaebccc2696671a303d386bba 214 SMART SM00421 151 208 8.8E-22 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_03950 bfd1c33fda6fb95477eaa5bc09277b72 184 SUPERFAMILY SSF52833 5 182 2.31E-48 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_03950 bfd1c33fda6fb95477eaa5bc09277b72 184 Gene3D G3DSA:3.40.30.10 7 183 5.4E-45 T 14-10-2018 TSH58p_03950 bfd1c33fda6fb95477eaa5bc09277b72 184 Pfam PF00578 AhpC/TSA family 11 131 1.7E-22 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TSH58p_27565 1b241e0467d009d6a54bcea537085295 264 Gene3D G3DSA:3.40.50.300 20 261 1.1E-47 T 14-10-2018 TSH58p_27565 1b241e0467d009d6a54bcea537085295 264 PIRSF PIRSF003092 8 264 2.6E-60 T 14-10-2018 IPR025501 ATP binding protein MinD TSH58p_27565 1b241e0467d009d6a54bcea537085295 264 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 22 239 1.1E-13 T 14-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TSH58p_27565 1b241e0467d009d6a54bcea537085295 264 SUPERFAMILY SSF52540 20 261 6.74E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_30040 fae3ea7588c54ce56af6cb718d95dd68 739 SUPERFAMILY SSF52540 71 438 3.36E-10 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_30040 fae3ea7588c54ce56af6cb718d95dd68 739 Gene3D G3DSA:3.40.50.300 72 137 3.1E-5 T 14-10-2018 TSH58p_00950 70a4328e453b48c2f05e8b6af8eb8065 310 Gene3D G3DSA:3.30.930.10 17 309 3.8E-89 T 14-10-2018 TSH58p_00950 70a4328e453b48c2f05e8b6af8eb8065 310 SUPERFAMILY SSF55681 15 308 7.46E-21 T 14-10-2018 TSH58p_20900 1209803331c30557881d071f6dd29a8f 234 SUPERFAMILY SSF51735 4 231 1.08E-61 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_20900 1209803331c30557881d071f6dd29a8f 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 4.1E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_20900 1209803331c30557881d071f6dd29a8f 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 4.1E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_20900 1209803331c30557881d071f6dd29a8f 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 4.1E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_20900 1209803331c30557881d071f6dd29a8f 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 4.1E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_20900 1209803331c30557881d071f6dd29a8f 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 4.1E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_20900 1209803331c30557881d071f6dd29a8f 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 4.1E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_20900 1209803331c30557881d071f6dd29a8f 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 3.3E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_20900 1209803331c30557881d071f6dd29a8f 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 3.3E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_20900 1209803331c30557881d071f6dd29a8f 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 3.3E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_20900 1209803331c30557881d071f6dd29a8f 234 Gene3D G3DSA:3.40.50.720 2 233 8.2E-68 T 14-10-2018 TSH58p_20900 1209803331c30557881d071f6dd29a8f 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 230 3.9E-47 T 14-10-2018 TSH58p_27660 477519d7f656f2cfcf77e98657b518f7 346 SUPERFAMILY SSF53850 43 331 3.34E-64 T 14-10-2018 TSH58p_27660 477519d7f656f2cfcf77e98657b518f7 346 Gene3D G3DSA:3.40.190.10 150 326 5.9E-70 T 14-10-2018 TSH58p_27660 477519d7f656f2cfcf77e98657b518f7 346 PIRSF PIRSF002825 1 342 1.1E-62 T 14-10-2018 IPR026045 Ferric binding protein TSH58p_27660 477519d7f656f2cfcf77e98657b518f7 346 Pfam PF13531 Bacterial extracellular solute-binding protein 48 300 6.3E-27 T 14-10-2018 TSH58p_27660 477519d7f656f2cfcf77e98657b518f7 346 Gene3D G3DSA:3.40.190.10 49 313 5.9E-70 T 14-10-2018 TSH58p_07465 25623860a6f7911a2910c231e63c1e64 225 SUPERFAMILY SSF56925 37 179 4.97E-7 T 14-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel TSH58p_07465 25623860a6f7911a2910c231e63c1e64 225 Gene3D G3DSA:2.40.160.170 17 225 1.2E-46 T 14-10-2018 TSH58p_05695 af860cdcb18e120eb45bcc9799f3b0cd 175 Gene3D G3DSA:3.40.630.30 4 175 6.3E-41 T 14-10-2018 TSH58p_05695 af860cdcb18e120eb45bcc9799f3b0cd 175 SUPERFAMILY SSF55729 19 175 9.39E-21 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_05695 af860cdcb18e120eb45bcc9799f3b0cd 175 Pfam PF00583 Acetyltransferase (GNAT) family 58 147 2.5E-7 T 14-10-2018 IPR000182 GNAT domain TSH58p_25180 86f56b3ef0eb5745c6d3087b6067e58d 71 Pfam PF04102 SlyX 6 71 1.8E-22 T 14-10-2018 IPR007236 SlyX TSH58p_25180 86f56b3ef0eb5745c6d3087b6067e58d 71 Hamap MF_00715 Protein SlyX [slyX]. 4 71 14.471 T 14-10-2018 IPR007236 SlyX TSH58p_08890 585ed0e5fcda94cd57cf6afa6af52317 135 SUPERFAMILY SSF46785 11 101 2.36E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_08890 585ed0e5fcda94cd57cf6afa6af52317 135 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 21 82 4.0E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_08890 585ed0e5fcda94cd57cf6afa6af52317 135 Gene3D G3DSA:1.10.10.10 1 124 1.6E-36 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_28950 4a07b8a78961a03a1822c6894b20e315 483 SMART SM00845 335 481 1.0E-87 T 14-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 TSH58p_28950 4a07b8a78961a03a1822c6894b20e315 483 SUPERFAMILY SSF55931 12 303 1.24E-114 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TSH58p_28950 4a07b8a78961a03a1822c6894b20e315 483 Pfam PF02934 GatB/GatE catalytic domain 13 296 1.0E-113 T 14-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 TSH58p_28950 4a07b8a78961a03a1822c6894b20e315 483 Gene3D G3DSA:1.10.10.410 421 483 2.5E-26 T 14-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal TSH58p_28950 4a07b8a78961a03a1822c6894b20e315 483 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 10 481 2.0E-165 T 14-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 TSH58p_28950 4a07b8a78961a03a1822c6894b20e315 483 Pfam PF02637 GatB domain 335 481 1.6E-55 T 14-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 TSH58p_28950 4a07b8a78961a03a1822c6894b20e315 483 Gene3D G3DSA:1.10.150.380 304 420 5.7E-42 T 14-10-2018 TSH58p_28950 4a07b8a78961a03a1822c6894b20e315 483 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 152 166 - T 14-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 TSH58p_28950 4a07b8a78961a03a1822c6894b20e315 483 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 10 482 37.734 T 14-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 TSH58p_28950 4a07b8a78961a03a1822c6894b20e315 483 SUPERFAMILY SSF89095 304 409 4.71E-37 T 14-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 TSH58p_25865 57f7809a6132b77f01f030ec932a3dc3 245 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 69 232 1.5E-14 T 14-10-2018 IPR010664 Lipopolysaccharide assembly, LptC-related TSH58p_25865 57f7809a6132b77f01f030ec932a3dc3 245 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 66 232 2.7E-16 T 14-10-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 TSH58p_23945 3ed70e1bd56bd60aea735999f2f66a92 198 Pfam PF06938 Protein of unknown function (DUF1285) 45 190 1.7E-58 T 14-10-2018 IPR010707 Protein of unknown function DUF1285 TSH58p_23945 3ed70e1bd56bd60aea735999f2f66a92 198 Gene3D G3DSA:3.10.540.10 20 96 6.7E-22 T 14-10-2018 TSH58p_23945 3ed70e1bd56bd60aea735999f2f66a92 198 Gene3D G3DSA:2.30.270.10 97 166 7.7E-31 T 14-10-2018 IPR023361 DUF1285, beta-roll domain superfamily TSH58p_00720 d3ec120e3a56baf26eede6e926d105a8 294 SUPERFAMILY SSF161098 52 280 7.72E-46 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_00720 d3ec120e3a56baf26eede6e926d105a8 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 289 6.8E-16 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_00720 d3ec120e3a56baf26eede6e926d105a8 294 Gene3D G3DSA:1.10.3720.10 46 293 1.3E-49 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_18815 a6ca8bcd1fb4c2176b25c3a8b753f87d 222 Gene3D G3DSA:1.10.3720.10 3 218 1.6E-54 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_18815 a6ca8bcd1fb4c2176b25c3a8b753f87d 222 SUPERFAMILY SSF161098 10 209 2.22E-48 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_18815 a6ca8bcd1fb4c2176b25c3a8b753f87d 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 216 1.3E-25 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_07365 e3dad41a4e52ac496c7d9f4112652c9d 109 SUPERFAMILY SSF54292 1 101 3.77E-33 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TSH58p_07365 e3dad41a4e52ac496c7d9f4112652c9d 109 PRINTS PR00355 Adrenodoxin signature 58 72 2.9E-11 T 14-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 TSH58p_07365 e3dad41a4e52ac496c7d9f4112652c9d 109 PRINTS PR00355 Adrenodoxin signature 39 49 2.9E-11 T 14-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 TSH58p_07365 e3dad41a4e52ac496c7d9f4112652c9d 109 PRINTS PR00355 Adrenodoxin signature 81 89 2.9E-11 T 14-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 TSH58p_07365 e3dad41a4e52ac496c7d9f4112652c9d 109 Gene3D G3DSA:3.10.20.30 2 109 4.6E-43 T 14-10-2018 IPR012675 Beta-grasp domain superfamily TSH58p_07365 e3dad41a4e52ac496c7d9f4112652c9d 109 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 39 49 - T 14-10-2018 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 TSH58p_07365 e3dad41a4e52ac496c7d9f4112652c9d 109 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 7 89 8.4E-14 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 TSH58p_31040 619d9cfc29ea365d4971fb13b7a94880 511 Gene3D G3DSA:3.40.50.12780 18 398 1.5E-129 T 14-10-2018 TSH58p_31040 619d9cfc29ea365d4971fb13b7a94880 511 SUPERFAMILY SSF56801 4 502 1.06E-140 T 14-10-2018 TSH58p_31040 619d9cfc29ea365d4971fb13b7a94880 511 ProSitePatterns PS00455 Putative AMP-binding domain signature. 162 173 - T 14-10-2018 IPR020845 AMP-binding, conserved site TSH58p_31040 619d9cfc29ea365d4971fb13b7a94880 511 Gene3D G3DSA:3.30.300.310 401 505 4.6E-25 T 14-10-2018 TSH58p_31040 619d9cfc29ea365d4971fb13b7a94880 511 Pfam PF13193 AMP-binding enzyme C-terminal domain 414 490 6.7E-13 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSH58p_31040 619d9cfc29ea365d4971fb13b7a94880 511 Pfam PF00501 AMP-binding enzyme 20 405 2.1E-98 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_27460 af8af9973b2e48462eaa70d51ab319ab 488 PIRSF PIRSF005522 1 477 2.0E-215 T 14-10-2018 IPR016450 Uncharacterised conserved protein UCP005522 TSH58p_27460 af8af9973b2e48462eaa70d51ab319ab 488 Gene3D G3DSA:3.40.50.11290 214 311 1.4E-42 T 14-10-2018 TSH58p_27460 af8af9973b2e48462eaa70d51ab319ab 488 SUPERFAMILY SSF56059 45 466 9.59E-61 T 14-10-2018 TSH58p_27460 af8af9973b2e48462eaa70d51ab319ab 488 Gene3D G3DSA:3.30.1490.270 349 408 6.0E-24 T 14-10-2018 TSH58p_27460 af8af9973b2e48462eaa70d51ab319ab 488 Pfam PF14403 Circularly permuted ATP-grasp type 2 76 451 5.4E-162 T 14-10-2018 IPR025841 Circularly permuted ATP-grasp type 2 TSH58p_20655 2b0202c98a8a63200d1ee5737982e78e 208 Gene3D G3DSA:2.30.110.10 36 159 1.5E-16 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TSH58p_20655 2b0202c98a8a63200d1ee5737982e78e 208 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 37 124 6.5E-9 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 TSH58p_20655 2b0202c98a8a63200d1ee5737982e78e 208 SUPERFAMILY SSF50475 12 177 6.28E-18 T 14-10-2018 TSH58p_20655 2b0202c98a8a63200d1ee5737982e78e 208 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 12 207 1.3E-60 T 14-10-2018 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent TSH58p_31485 4114aec863e0b099f7dd3e4d0a9210f5 519 Pfam PF00005 ABC transporter 21 170 2.3E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_31485 4114aec863e0b099f7dd3e4d0a9210f5 519 Gene3D G3DSA:3.40.50.300 5 242 1.7E-53 T 14-10-2018 TSH58p_31485 4114aec863e0b099f7dd3e4d0a9210f5 519 Gene3D G3DSA:3.40.50.300 263 491 1.8E-35 T 14-10-2018 TSH58p_31485 4114aec863e0b099f7dd3e4d0a9210f5 519 Pfam PF00005 ABC transporter 273 424 1.9E-16 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_31485 4114aec863e0b099f7dd3e4d0a9210f5 519 SUPERFAMILY SSF52540 4 231 4.44E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_31485 4114aec863e0b099f7dd3e4d0a9210f5 519 ProSitePatterns PS00211 ABC transporters family signature. 397 411 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_31485 4114aec863e0b099f7dd3e4d0a9210f5 519 SUPERFAMILY SSF52540 270 477 4.56E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_31485 4114aec863e0b099f7dd3e4d0a9210f5 519 SMART SM00382 30 218 1.3E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_31485 4114aec863e0b099f7dd3e4d0a9210f5 519 SMART SM00382 280 473 1.7E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_11335 d814b04cdace8126fa08694532f4c233 277 SMART SM00563 78 194 1.0E-24 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TSH58p_11335 d814b04cdace8126fa08694532f4c233 277 SUPERFAMILY SSF69593 26 264 1.83E-29 T 14-10-2018 TSH58p_11335 d814b04cdace8126fa08694532f4c233 277 Pfam PF01553 Acyltransferase 70 191 2.2E-21 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TSH58p_10780 4f0af79e6c818654a5daf9d3b3927f5a 211 SUPERFAMILY SSF51161 20 205 3.05E-45 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily TSH58p_10780 4f0af79e6c818654a5daf9d3b3927f5a 211 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 118 146 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 TSH58p_10780 4f0af79e6c818654a5daf9d3b3927f5a 211 Gene3D G3DSA:2.160.10.10 1 209 8.1E-73 T 14-10-2018 TSH58p_10780 4f0af79e6c818654a5daf9d3b3927f5a 211 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 109 143 2.9E-9 T 14-10-2018 IPR001451 Hexapeptide repeat TSH58p_15110 5e9255e40cfc87b9a02b5268ac740aa4 233 Gene3D G3DSA:3.30.190.20 21 225 4.3E-81 T 14-10-2018 TSH58p_15110 5e9255e40cfc87b9a02b5268ac740aa4 233 Pfam PF00687 Ribosomal protein L1p/L10e family 34 220 9.9E-54 T 14-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein TSH58p_15110 5e9255e40cfc87b9a02b5268ac740aa4 233 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 3.0E-101 T 14-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 TSH58p_15110 5e9255e40cfc87b9a02b5268ac740aa4 233 SUPERFAMILY SSF56808 7 226 4.97E-82 T 14-10-2018 IPR023674 Ribosomal protein L1-like TSH58p_15110 5e9255e40cfc87b9a02b5268ac740aa4 233 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 42.989 T 14-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 TSH58p_15110 5e9255e40cfc87b9a02b5268ac740aa4 233 ProSitePatterns PS01199 Ribosomal protein L1 signature. 120 139 - T 14-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15110 5e9255e40cfc87b9a02b5268ac740aa4 233 PIRSF PIRSF002155 1 227 3.2E-78 T 14-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15110 5e9255e40cfc87b9a02b5268ac740aa4 233 Gene3D G3DSA:3.40.50.790 68 159 4.3E-81 T 14-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich TSH58p_15200 08301f460359eeb29f59cb27ffcc3f9d 143 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 14-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15200 08301f460359eeb29f59cb27ffcc3f9d 143 PRINTS PR00060 Ribosomal protein L16 signature 58 87 3.3E-39 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_15200 08301f460359eeb29f59cb27ffcc3f9d 143 PRINTS PR00060 Ribosomal protein L16 signature 88 117 3.3E-39 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_15200 08301f460359eeb29f59cb27ffcc3f9d 143 PRINTS PR00060 Ribosomal protein L16 signature 24 36 3.3E-39 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_15200 08301f460359eeb29f59cb27ffcc3f9d 143 PRINTS PR00060 Ribosomal protein L16 signature 42 53 3.3E-39 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_15200 08301f460359eeb29f59cb27ffcc3f9d 143 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 2.6E-58 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_15200 08301f460359eeb29f59cb27ffcc3f9d 143 SUPERFAMILY SSF54686 1 134 1.31E-56 T 14-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 TSH58p_15200 08301f460359eeb29f59cb27ffcc3f9d 143 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 1.1E-51 T 14-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 TSH58p_15200 08301f460359eeb29f59cb27ffcc3f9d 143 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 14-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15200 08301f460359eeb29f59cb27ffcc3f9d 143 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 38.79 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_15200 08301f460359eeb29f59cb27ffcc3f9d 143 Gene3D G3DSA:3.90.1170.10 1 140 9.0E-59 T 14-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 TSH58p_28485 aa4666edd9482ecb80450d0bc9c8cb53 373 SUPERFAMILY SSF102405 86 288 1.14E-40 T 14-10-2018 TSH58p_28485 aa4666edd9482ecb80450d0bc9c8cb53 373 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 74 287 4.0E-65 T 14-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 TSH58p_28485 aa4666edd9482ecb80450d0bc9c8cb53 373 Gene3D G3DSA:3.40.50.450 3 291 1.5E-106 T 14-10-2018 TSH58p_28485 aa4666edd9482ecb80450d0bc9c8cb53 373 Pfam PF02481 DNA recombination-mediator protein A 79 279 2.6E-70 T 14-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 TSH58p_28485 aa4666edd9482ecb80450d0bc9c8cb53 373 Gene3D G3DSA:1.10.10.10 302 372 3.5E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_04620 6bb7ffc7dcf51b6fe17a888c9bccbeb0 155 Gene3D G3DSA:1.10.40.40 17 49 2.2E-8 T 14-10-2018 TSH58p_04620 6bb7ffc7dcf51b6fe17a888c9bccbeb0 155 SUPERFAMILY SSF56784 4 140 4.95E-11 T 14-10-2018 IPR036412 HAD-like superfamily TSH58p_04620 6bb7ffc7dcf51b6fe17a888c9bccbeb0 155 Gene3D G3DSA:3.40.50.1000 8 136 2.2E-8 T 14-10-2018 IPR023214 HAD superfamily TSH58p_11620 ac7d6d7236db2c2b4022f64b8a5211f8 498 SUPERFAMILY SSF81442 24 481 1.96E-122 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_11620 ac7d6d7236db2c2b4022f64b8a5211f8 498 Gene3D G3DSA:1.20.210.10 16 489 7.3E-193 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_11620 ac7d6d7236db2c2b4022f64b8a5211f8 498 TIGRFAM TIGR00780 ccoN: cytochrome c oxidase, cbb3-type, subunit I 24 488 9.3E-225 T 14-10-2018 IPR004677 Cytochrome c oxidase cbb3-type, subunit I GO:0004129|GO:0045278|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 TSH58p_11620 ac7d6d7236db2c2b4022f64b8a5211f8 498 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 220 275 - T 14-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_11620 ac7d6d7236db2c2b4022f64b8a5211f8 498 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 27 460 1.1E-116 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_11625 7049afa8fd90480ca696871def37ba49 246 Gene3D G3DSA:1.10.760.10 47 237 4.2E-67 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_11625 7049afa8fd90480ca696871def37ba49 246 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 10 233 6.2E-98 T 14-10-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO TSH58p_11625 7049afa8fd90480ca696871def37ba49 246 TIGRFAM TIGR00781 ccoO: cytochrome c oxidase, cbb3-type, subunit II 11 239 3.9E-107 T 14-10-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO TSH58p_11625 7049afa8fd90480ca696871def37ba49 246 SUPERFAMILY SSF46626 21 227 3.25E-27 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_31480 2785b9ebbe82d5ca801f18ffb5fb4339 329 Pfam PF02653 Branched-chain amino acid transport system / permease component 42 319 5.2E-43 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_04125 10e4f9f40d6fe569d8d93354182fc8c0 251 SUPERFAMILY SSF52540 5 247 9.48E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_04125 10e4f9f40d6fe569d8d93354182fc8c0 251 Pfam PF00005 ABC transporter 23 178 6.1E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_04125 10e4f9f40d6fe569d8d93354182fc8c0 251 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 247 6.2E-9 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSH58p_04125 10e4f9f40d6fe569d8d93354182fc8c0 251 Gene3D G3DSA:3.40.50.300 4 249 1.8E-59 T 14-10-2018 TSH58p_04125 10e4f9f40d6fe569d8d93354182fc8c0 251 SMART SM00382 31 225 1.6E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_08450 fa057348073516edc01dcf18250615bb 276 PIRSF PIRSF028756 1 272 9.8E-116 T 14-10-2018 IPR016898 Polyphosphate kinase 2 KEGG: 00190+2.7.4.1 TSH58p_08450 fa057348073516edc01dcf18250615bb 276 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 18 242 6.6E-97 T 14-10-2018 IPR022488 Polyphosphate kinase-2-related TSH58p_08450 fa057348073516edc01dcf18250615bb 276 Gene3D G3DSA:3.40.50.300 1 255 1.1E-89 T 14-10-2018 TSH58p_08450 fa057348073516edc01dcf18250615bb 276 SUPERFAMILY SSF52540 49 236 7.23E-26 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_08450 fa057348073516edc01dcf18250615bb 276 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 17 244 2.6E-107 T 14-10-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 KEGG: 00190+2.7.4.1 TSH58p_16050 05a4eb02458e4aff694dd84b275830ee 284 Gene3D G3DSA:1.10.287.70 17 81 8.7E-24 T 14-10-2018 TSH58p_16050 05a4eb02458e4aff694dd84b275830ee 284 Pfam PF00510 Cytochrome c oxidase subunit III 19 277 3.9E-95 T 14-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16050 05a4eb02458e4aff694dd84b275830ee 284 SUPERFAMILY SSF81452 18 276 2.3E-96 T 14-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_16050 05a4eb02458e4aff694dd84b275830ee 284 Gene3D G3DSA:1.20.120.80 84 277 8.7E-76 T 14-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_02075 609714a0398d7804fdde59db9b5f4054 203 SUPERFAMILY SSF46894 138 200 2.76E-17 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_02075 609714a0398d7804fdde59db9b5f4054 203 Pfam PF00196 Bacterial regulatory proteins, luxR family 144 198 8.7E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_02075 609714a0398d7804fdde59db9b5f4054 203 ProSitePatterns PS00622 LuxR-type HTH domain signature. 159 186 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_02075 609714a0398d7804fdde59db9b5f4054 203 SMART SM00448 7 118 2.0E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_02075 609714a0398d7804fdde59db9b5f4054 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 175 4.3E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_02075 609714a0398d7804fdde59db9b5f4054 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 187 4.3E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_02075 609714a0398d7804fdde59db9b5f4054 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 145 159 4.3E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_02075 609714a0398d7804fdde59db9b5f4054 203 Pfam PF00072 Response regulator receiver domain 9 118 2.5E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_02075 609714a0398d7804fdde59db9b5f4054 203 SMART SM00421 142 199 5.5E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_02075 609714a0398d7804fdde59db9b5f4054 203 SUPERFAMILY SSF52172 7 159 6.69E-36 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_02075 609714a0398d7804fdde59db9b5f4054 203 Gene3D G3DSA:3.40.50.2300 2 134 6.5E-47 T 14-10-2018 TSH58p_02075 609714a0398d7804fdde59db9b5f4054 203 Gene3D G3DSA:1.10.10.10 135 202 6.3E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_18270 2b48cf717ee5c04424ac9707a1b2786c 345 Gene3D G3DSA:3.90.550.10 6 254 5.6E-41 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_18270 2b48cf717ee5c04424ac9707a1b2786c 345 Pfam PF00535 Glycosyl transferase family 2 33 184 2.9E-14 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_18270 2b48cf717ee5c04424ac9707a1b2786c 345 SUPERFAMILY SSF53448 26 270 9.14E-31 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_15450 a1c31d5e5f183529074dd628349ddc1b 245 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 9 61 7.6E-16 T 14-10-2018 IPR025713 Motility protein B, N-terminal domain TSH58p_15450 a1c31d5e5f183529074dd628349ddc1b 245 Gene3D G3DSA:3.30.1330.60 89 208 1.0E-9 T 14-10-2018 IPR036737 OmpA-like domain superfamily TSH58p_15450 a1c31d5e5f183529074dd628349ddc1b 245 SUPERFAMILY SSF103088 118 203 4.45E-7 T 14-10-2018 IPR036737 OmpA-like domain superfamily TSH58p_00770 48d5a4e3f5f3519929410119e67c7dc0 257 SUPERFAMILY SSF53474 4 242 7.96E-49 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_00770 48d5a4e3f5f3519929410119e67c7dc0 257 SMART SM00824 Thioesterase 24 243 5.4E-4 T 14-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 TSH58p_00770 48d5a4e3f5f3519929410119e67c7dc0 257 Gene3D G3DSA:3.40.50.1820 20 247 1.6E-62 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_00770 48d5a4e3f5f3519929410119e67c7dc0 257 Pfam PF00975 Thioesterase domain 21 235 3.7E-44 T 14-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 TSH58p_17930 5f847a2f473088a739b1282349e31561 139 SMART SM00116 78 125 1.8E-4 T 14-10-2018 IPR000644 CBS domain TSH58p_17930 5f847a2f473088a739b1282349e31561 139 SMART SM00116 13 60 0.55 T 14-10-2018 IPR000644 CBS domain TSH58p_17930 5f847a2f473088a739b1282349e31561 139 SUPERFAMILY SSF54631 7 130 5.56E-25 T 14-10-2018 TSH58p_17930 5f847a2f473088a739b1282349e31561 139 Gene3D G3DSA:3.10.580.10 2 138 1.9E-29 T 14-10-2018 TSH58p_17930 5f847a2f473088a739b1282349e31561 139 Pfam PF00571 CBS domain 71 120 4.0E-8 T 14-10-2018 IPR000644 CBS domain TSH58p_17930 5f847a2f473088a739b1282349e31561 139 Pfam PF00571 CBS domain 10 59 6.9E-5 T 14-10-2018 IPR000644 CBS domain TSH58p_30605 a4d742c2be353e5e2a78cdc5819276c1 340 Gene3D G3DSA:3.40.190.10 115 220 6.8E-40 T 14-10-2018 TSH58p_30605 a4d742c2be353e5e2a78cdc5819276c1 340 SUPERFAMILY SSF53850 37 261 1.55E-35 T 14-10-2018 TSH58p_30605 a4d742c2be353e5e2a78cdc5819276c1 340 Pfam PF09084 NMT1/THI5 like 51 250 5.7E-22 T 14-10-2018 IPR015168 SsuA/THI5-like TSH58p_30605 a4d742c2be353e5e2a78cdc5819276c1 340 Gene3D G3DSA:1.10.8.450 252 283 6.8E-40 T 14-10-2018 TSH58p_30605 a4d742c2be353e5e2a78cdc5819276c1 340 Gene3D G3DSA:3.40.190.10 51 311 6.8E-40 T 14-10-2018 TSH58p_00380 2d180904c6edc20ffdf5a1e6fa197d58 187 SUPERFAMILY SSF46689 5 68 4.87E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_00380 2d180904c6edc20ffdf5a1e6fa197d58 187 Gene3D G3DSA:1.10.357.10 2 183 4.7E-20 T 14-10-2018 TSH58p_00380 2d180904c6edc20ffdf5a1e6fa197d58 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 1.9E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_00380 2d180904c6edc20ffdf5a1e6fa197d58 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 2.2E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_00380 2d180904c6edc20ffdf5a1e6fa197d58 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 2.2E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_21170 31c1071f2bcaf8756e8e8f973441ac9a 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 9.1E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_21170 31c1071f2bcaf8756e8e8f973441ac9a 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 9.1E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_21170 31c1071f2bcaf8756e8e8f973441ac9a 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 186 9.1E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_21170 31c1071f2bcaf8756e8e8f973441ac9a 275 Pfam PF00106 short chain dehydrogenase 10 199 6.9E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_21170 31c1071f2bcaf8756e8e8f973441ac9a 275 SUPERFAMILY SSF51735 6 246 9.88E-52 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_21170 31c1071f2bcaf8756e8e8f973441ac9a 275 Gene3D G3DSA:3.40.50.720 2 275 8.4E-74 T 14-10-2018 TSH58p_15145 70cde996285bc862d9a2a68198f54d96 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.843 T 14-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 TSH58p_15145 70cde996285bc862d9a2a68198f54d96 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 1.9E-69 T 14-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 TSH58p_15145 70cde996285bc862d9a2a68198f54d96 156 Gene3D G3DSA:1.10.455.10 2 156 1.2E-61 T 14-10-2018 IPR036823 Ribosomal protein S7 domain superfamily TSH58p_15145 70cde996285bc862d9a2a68198f54d96 156 PIRSF PIRSF002122 2 156 8.1E-60 T 14-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 TSH58p_15145 70cde996285bc862d9a2a68198f54d96 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 14-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15145 70cde996285bc862d9a2a68198f54d96 156 SUPERFAMILY SSF47973 1 149 4.45E-61 T 14-10-2018 IPR036823 Ribosomal protein S7 domain superfamily TSH58p_15145 70cde996285bc862d9a2a68198f54d96 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 1.5E-66 T 14-10-2018 IPR023798 Ribosomal protein S7 domain TSH58p_03305 fa56d3611c025f3da8ae80b7e8e4879a 219 SUPERFAMILY SSF100950 39 218 3.85E-41 T 14-10-2018 IPR037171 NagB/RpiA transferase-like TSH58p_03305 fa56d3611c025f3da8ae80b7e8e4879a 219 Gene3D G3DSA:3.40.50.10420 36 218 6.7E-40 T 14-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily TSH58p_03305 fa56d3611c025f3da8ae80b7e8e4879a 219 Pfam PF02589 LUD domain 42 218 8.3E-28 T 14-10-2018 IPR003741 LUD domain TSH58p_21855 f9ba8c34ae639d597fde9fabdcd0f4e5 303 SUPERFAMILY SSF103481 206 300 4.97E-16 T 14-10-2018 TSH58p_21855 f9ba8c34ae639d597fde9fabdcd0f4e5 303 Pfam PF00892 EamA-like transporter family 162 296 8.5E-13 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_21855 f9ba8c34ae639d597fde9fabdcd0f4e5 303 Pfam PF00892 EamA-like transporter family 25 150 8.2E-15 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_21855 f9ba8c34ae639d597fde9fabdcd0f4e5 303 SUPERFAMILY SSF103481 55 152 1.44E-12 T 14-10-2018 TSH58p_12625 dc0fe8ca3aba9bd9bffe5082660c4cd9 196 SUPERFAMILY SSF55811 8 180 1.3E-36 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TSH58p_12625 dc0fe8ca3aba9bd9bffe5082660c4cd9 196 Gene3D G3DSA:3.90.79.10 5 186 6.2E-44 T 14-10-2018 TSH58p_12625 dc0fe8ca3aba9bd9bffe5082660c4cd9 196 Pfam PF00293 NUDIX domain 48 159 2.8E-13 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TSH58p_22910 5d77a8b3ccffea342a5b05fd4e1df4a2 582 Pfam PF02538 Hydantoinase B/oxoprolinase 10 532 1.1E-168 T 14-10-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 TSH58p_28980 a26c765f3ed0871ed9b777b0f8068bc8 300 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 9 273 3.0E-52 T 14-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 TSH58p_28980 a26c765f3ed0871ed9b777b0f8068bc8 300 SUPERFAMILY SSF51197 6 286 1.1E-82 T 14-10-2018 TSH58p_28980 a26c765f3ed0871ed9b777b0f8068bc8 300 Gene3D G3DSA:3.60.130.10 3 291 1.5E-87 T 14-10-2018 TSH58p_31285 23877bd0a9f57498db76bd92c9a2eccc 88 Pfam PF10025 Uncharacterized conserved protein (DUF2267) 5 83 1.3E-13 T 14-10-2018 IPR018727 Protein of unknown function DUF2267 TSH58p_31285 23877bd0a9f57498db76bd92c9a2eccc 88 Gene3D G3DSA:1.10.490.110 3 85 5.5E-19 T 14-10-2018 TSH58p_24730 5f0f03b4b6292743d167e2ae3e8ebc94 66 Pfam PF03884 DNA gyrase inhibitor YacG 16 60 7.6E-13 T 14-10-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 TSH58p_24730 5f0f03b4b6292743d167e2ae3e8ebc94 66 Hamap MF_00649 DNA gyrase inhibitor YacG [yacG]. 11 65 15.531 T 14-10-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 TSH58p_24730 5f0f03b4b6292743d167e2ae3e8ebc94 66 SUPERFAMILY SSF57716 13 64 1.4E-13 T 14-10-2018 TSH58p_24730 5f0f03b4b6292743d167e2ae3e8ebc94 66 Gene3D G3DSA:3.30.50.10 10 66 2.7E-15 T 14-10-2018 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 Reactome: R-HSA-383280 TSH58p_08920 5d02ee374a2965d4e4712ff7339f8990 147 Pfam PF03979 Sigma-70 factor, region 1.1 5 59 3.0E-5 T 14-10-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 TSH58p_08925 4708dbee32400aaee229646df8c610f1 210 Pfam PF01625 Peptide methionine sulfoxide reductase 48 199 4.0E-68 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 TSH58p_08925 4708dbee32400aaee229646df8c610f1 210 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 44 205 39.366 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 TSH58p_08925 4708dbee32400aaee229646df8c610f1 210 Gene3D G3DSA:3.30.1060.10 5 210 1.7E-96 T 14-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 TSH58p_08925 4708dbee32400aaee229646df8c610f1 210 SUPERFAMILY SSF55068 5 208 8.63E-84 T 14-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 TSH58p_08925 4708dbee32400aaee229646df8c610f1 210 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 46 199 2.5E-68 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 TSH58p_15375 0fd3ad7421738a309bb2c25c41d43e73 127 Pfam PF10135 Rod binding protein 71 116 2.3E-13 T 14-10-2018 IPR019301 Flagellar protein FlgJ, N-terminal TSH58p_16290 653bb3f3f417db4a670ebc6a5b0cfe77 363 SUPERFAMILY SSF46785 264 338 3.88E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_16290 653bb3f3f417db4a670ebc6a5b0cfe77 363 SMART SM00382 59 186 5.0E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_16290 653bb3f3f417db4a670ebc6a5b0cfe77 363 SUPERFAMILY SSF52540 28 259 4.7E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_16290 653bb3f3f417db4a670ebc6a5b0cfe77 363 Gene3D G3DSA:1.10.10.10 265 344 1.1E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_16290 653bb3f3f417db4a670ebc6a5b0cfe77 363 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 32 334 6.0E-134 T 14-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 TSH58p_16290 653bb3f3f417db4a670ebc6a5b0cfe77 363 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 261 334 3.8E-32 T 14-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 TSH58p_16290 653bb3f3f417db4a670ebc6a5b0cfe77 363 Gene3D G3DSA:3.40.50.300 27 189 2.9E-38 T 14-10-2018 TSH58p_16290 653bb3f3f417db4a670ebc6a5b0cfe77 363 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 259 339 8.0E-27 T 14-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 TSH58p_16290 653bb3f3f417db4a670ebc6a5b0cfe77 363 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 363 167.729 T 14-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 TSH58p_16290 653bb3f3f417db4a670ebc6a5b0cfe77 363 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 22 242 2.4E-110 T 14-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 TSH58p_16290 653bb3f3f417db4a670ebc6a5b0cfe77 363 Gene3D G3DSA:1.10.8.60 190 264 1.1E-25 T 14-10-2018 TSH58p_10860 6b1a51049dacacd71ecb75c0689be172 879 SUPERFAMILY SSF52540 349 864 3.2E-28 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_10860 6b1a51049dacacd71ecb75c0689be172 879 Pfam PF00005 ABC transporter 728 809 6.1E-6 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_10860 6b1a51049dacacd71ecb75c0689be172 879 Gene3D G3DSA:1.20.1560.10 3 324 5.9E-41 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_10860 6b1a51049dacacd71ecb75c0689be172 879 SUPERFAMILY SSF90123 10 328 2.62E-45 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_10860 6b1a51049dacacd71ecb75c0689be172 879 Gene3D G3DSA:3.40.50.300 343 507 1.5E-15 T 14-10-2018 TSH58p_10860 6b1a51049dacacd71ecb75c0689be172 879 Gene3D G3DSA:3.40.50.300 681 879 9.0E-31 T 14-10-2018 TSH58p_10860 6b1a51049dacacd71ecb75c0689be172 879 Pfam PF00664 ABC transporter transmembrane region 67 290 3.4E-20 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TSH58p_29320 d4e1da99fc3164ff342cf6446fb7716b 545 Pfam PF00501 AMP-binding enzyme 51 442 1.1E-77 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_29320 d4e1da99fc3164ff342cf6446fb7716b 545 SUPERFAMILY SSF56801 26 540 4.71E-132 T 14-10-2018 TSH58p_29320 d4e1da99fc3164ff342cf6446fb7716b 545 ProSitePatterns PS00455 Putative AMP-binding domain signature. 196 207 - T 14-10-2018 IPR020845 AMP-binding, conserved site TSH58p_29320 d4e1da99fc3164ff342cf6446fb7716b 545 Pfam PF13193 AMP-binding enzyme C-terminal domain 451 529 1.1E-21 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSH58p_29320 d4e1da99fc3164ff342cf6446fb7716b 545 Gene3D G3DSA:3.40.50.12780 30 438 1.2E-93 T 14-10-2018 TSH58p_29320 d4e1da99fc3164ff342cf6446fb7716b 545 Gene3D G3DSA:3.30.300.310 439 543 5.9E-29 T 14-10-2018 TSH58p_11760 9aa567a648e90af6d7a2695692a0d016 328 Pfam PF00950 ABC 3 transport family 14 136 7.1E-23 T 14-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 TSH58p_11760 9aa567a648e90af6d7a2695692a0d016 328 Pfam PF00950 ABC 3 transport family 158 276 1.1E-18 T 14-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 TSH58p_11760 9aa567a648e90af6d7a2695692a0d016 328 SUPERFAMILY SSF81345 8 275 9.29E-26 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_26575 4b5d51f486989d27423a89da5d024abe 388 Pfam PF07993 Male sterility protein 4 233 4.0E-32 T 14-10-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 TSH58p_26575 4b5d51f486989d27423a89da5d024abe 388 SUPERFAMILY SSF51735 2 349 8.81E-29 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_26575 4b5d51f486989d27423a89da5d024abe 388 Gene3D G3DSA:3.40.50.720 1 283 3.2E-47 T 14-10-2018 TSH58p_06685 ab6eca224c2902b772b3411b4717234e 145 SMART SM00116 80 128 6.7E-6 T 14-10-2018 IPR000644 CBS domain TSH58p_06685 ab6eca224c2902b772b3411b4717234e 145 SMART SM00116 14 62 2.8E-8 T 14-10-2018 IPR000644 CBS domain TSH58p_06685 ab6eca224c2902b772b3411b4717234e 145 SUPERFAMILY SSF54631 4 140 1.11E-33 T 14-10-2018 TSH58p_06685 ab6eca224c2902b772b3411b4717234e 145 Pfam PF00571 CBS domain 73 128 3.0E-12 T 14-10-2018 IPR000644 CBS domain TSH58p_06685 ab6eca224c2902b772b3411b4717234e 145 Pfam PF00571 CBS domain 15 62 2.8E-10 T 14-10-2018 IPR000644 CBS domain TSH58p_06685 ab6eca224c2902b772b3411b4717234e 145 Gene3D G3DSA:3.10.580.10 1 142 5.3E-43 T 14-10-2018 TSH58p_08765 936e70552ed97fe9511a956154377213 324 Pfam PF00892 EamA-like transporter family 21 157 1.2E-8 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_08765 936e70552ed97fe9511a956154377213 324 SUPERFAMILY SSF103481 61 159 1.7E-8 T 14-10-2018 TSH58p_08765 936e70552ed97fe9511a956154377213 324 SUPERFAMILY SSF103481 207 297 5.1E-7 T 14-10-2018 TSH58p_08765 936e70552ed97fe9511a956154377213 324 TIGRFAM TIGR00688 rarD: protein RarD 24 273 1.6E-63 T 14-10-2018 IPR004626 RarD protein GO:0005887 TSH58p_26985 247822dfc926c26852b8ae70d9faffb0 297 Gene3D G3DSA:3.40.50.720 2 291 4.4E-101 T 14-10-2018 TSH58p_26985 247822dfc926c26852b8ae70d9faffb0 297 SUPERFAMILY SSF51735 8 286 8.0E-30 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_27370 e8bc9109e250078d0c7e1529f15b86b8 260 SUPERFAMILY SSF69593 8 232 2.62E-33 T 14-10-2018 TSH58p_27370 e8bc9109e250078d0c7e1529f15b86b8 260 SMART SM00563 72 186 3.1E-20 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TSH58p_27370 e8bc9109e250078d0c7e1529f15b86b8 260 Pfam PF01553 Acyltransferase 58 183 1.8E-17 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TSH58p_20860 36d1c35b53036514e5b4a359c4a6575f 70 Pfam PF06568 Domain of unknown function (DUF1127) 26 59 4.9E-7 T 14-10-2018 IPR009506 Protein of unknown function DUF1127 TSH58p_05485 123c64fb0ce92571ec2f7b98cb6a2793 168 Gene3D G3DSA:3.40.50.2300 43 165 1.2E-27 T 14-10-2018 TSH58p_05485 123c64fb0ce92571ec2f7b98cb6a2793 168 Pfam PF00072 Response regulator receiver domain 48 156 9.4E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_05485 123c64fb0ce92571ec2f7b98cb6a2793 168 SMART SM00448 45 156 3.9E-19 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_05485 123c64fb0ce92571ec2f7b98cb6a2793 168 SUPERFAMILY SSF52172 43 164 1.99E-26 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_13370 c8857be74d201dead089b989690e60e4 341 Gene3D G3DSA:3.10.450.240 215 341 1.8E-13 T 14-10-2018 TSH58p_13370 c8857be74d201dead089b989690e60e4 341 Pfam PF04280 Tim44-like domain 204 339 4.8E-29 T 14-10-2018 IPR007379 Tim44-like domain TSH58p_13370 c8857be74d201dead089b989690e60e4 341 SUPERFAMILY SSF54427 218 341 1.73E-23 T 14-10-2018 IPR032710 NTF2-like domain superfamily TSH58p_13370 c8857be74d201dead089b989690e60e4 341 SMART SM00978 196 339 2.7E-35 T 14-10-2018 IPR007379 Tim44-like domain TSH58p_13445 0b80a8c3473be495796e248a8cb31333 308 Gene3D G3DSA:3.40.50.720 92 274 1.7E-116 T 14-10-2018 TSH58p_13445 0b80a8c3473be495796e248a8cb31333 308 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 212 228 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TSH58p_13445 0b80a8c3473be495796e248a8cb31333 308 SUPERFAMILY SSF52283 35 110 9.35E-6 T 14-10-2018 TSH58p_13445 0b80a8c3473be495796e248a8cb31333 308 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 102 273 1.6E-47 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TSH58p_13445 0b80a8c3473be495796e248a8cb31333 308 Gene3D G3DSA:3.40.50.720 15 308 1.7E-116 T 14-10-2018 TSH58p_13445 0b80a8c3473be495796e248a8cb31333 308 SUPERFAMILY SSF51735 94 274 4.94E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_24935 f7cbbbd136753fe49d58e46a552201f8 163 ProSitePatterns PS01117 MarR-type HTH domain signature. 62 96 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site TSH58p_24935 f7cbbbd136753fe49d58e46a552201f8 163 SUPERFAMILY SSF46785 22 135 1.29E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_24935 f7cbbbd136753fe49d58e46a552201f8 163 Pfam PF12802 MarR family 27 87 4.4E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_24935 f7cbbbd136753fe49d58e46a552201f8 163 SMART SM00347 21 120 3.5E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_24935 f7cbbbd136753fe49d58e46a552201f8 163 Gene3D G3DSA:1.10.10.10 3 134 3.5E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_13640 b373a39d1190d9ff10d5766219c5fb08 182 SMART SM01049 50 131 1.4E-6 T 14-10-2018 IPR033480 Single Cache domain 2 TSH58p_13640 b373a39d1190d9ff10d5766219c5fb08 182 Pfam PF17200 Single Cache domain 2 76 166 4.0E-15 T 14-10-2018 IPR033480 Single Cache domain 2 TSH58p_13640 b373a39d1190d9ff10d5766219c5fb08 182 Gene3D G3DSA:3.30.450.20 61 181 5.1E-17 T 14-10-2018 TSH58p_04360 faba6ef55c3485db86260e134fca0939 202 SUPERFAMILY SSF55811 4 197 1.15E-41 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TSH58p_04360 faba6ef55c3485db86260e134fca0939 202 Pfam PF00293 NUDIX domain 47 170 1.8E-16 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TSH58p_04360 faba6ef55c3485db86260e134fca0939 202 ProSitePatterns PS00893 Nudix box signature. 88 109 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TSH58p_04360 faba6ef55c3485db86260e134fca0939 202 Gene3D G3DSA:3.90.79.10 1 200 3.3E-58 T 14-10-2018 TSH58p_04360 faba6ef55c3485db86260e134fca0939 202 TIGRFAM TIGR00052 TIGR00052: nudix-type nucleoside diphosphatase, YffH/AdpP family 5 188 6.5E-41 T 14-10-2018 IPR004385 Nucleoside diphosphate pyrophosphatase GO:0016818|GO:0046872 Reactome: R-HSA-480985 TSH58p_05285 091236ee470653d44a26b00a6f8fd325 172 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 13 47 7.7E-5 T 14-10-2018 IPR001451 Hexapeptide repeat TSH58p_05285 091236ee470653d44a26b00a6f8fd325 172 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 92 125 2.1E-4 T 14-10-2018 IPR001451 Hexapeptide repeat TSH58p_05285 091236ee470653d44a26b00a6f8fd325 172 SUPERFAMILY SSF51161 7 171 2.22E-48 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily TSH58p_05285 091236ee470653d44a26b00a6f8fd325 172 Gene3D G3DSA:2.160.10.10 3 172 4.6E-62 T 14-10-2018 TSH58p_19600 443c3ecf25dafa4c00aebefd9117106c 706 SMART SM00028 113 146 0.4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_19600 443c3ecf25dafa4c00aebefd9117106c 706 SMART SM00028 38 71 140.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_19600 443c3ecf25dafa4c00aebefd9117106c 706 SMART SM00028 4 37 230.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_19600 443c3ecf25dafa4c00aebefd9117106c 706 SMART SM00028 181 214 42.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_19600 443c3ecf25dafa4c00aebefd9117106c 706 SMART SM00028 317 350 0.44 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_19600 443c3ecf25dafa4c00aebefd9117106c 706 SMART SM00028 72 105 9.4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_19600 443c3ecf25dafa4c00aebefd9117106c 706 SMART SM00028 385 418 41.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_19600 443c3ecf25dafa4c00aebefd9117106c 706 SMART SM00028 249 282 54.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_19600 443c3ecf25dafa4c00aebefd9117106c 706 Pfam PF13432 Tetratricopeptide repeat 17 71 5.1E-6 T 14-10-2018 TSH58p_19600 443c3ecf25dafa4c00aebefd9117106c 706 Pfam PF13432 Tetratricopeptide repeat 328 370 1.3E-4 T 14-10-2018 TSH58p_19600 443c3ecf25dafa4c00aebefd9117106c 706 Pfam PF13432 Tetratricopeptide repeat 118 178 0.0016 T 14-10-2018 TSH58p_19600 443c3ecf25dafa4c00aebefd9117106c 706 Gene3D G3DSA:1.25.40.10 3 114 1.7E-14 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_19600 443c3ecf25dafa4c00aebefd9117106c 706 Gene3D G3DSA:3.40.50.11350 565 692 1.6E-5 T 14-10-2018 TSH58p_19600 443c3ecf25dafa4c00aebefd9117106c 706 SUPERFAMILY SSF48452 9 117 9.76E-15 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_19600 443c3ecf25dafa4c00aebefd9117106c 706 Gene3D G3DSA:1.25.40.10 115 437 1.8E-43 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_19600 443c3ecf25dafa4c00aebefd9117106c 706 SUPERFAMILY SSF48452 115 418 8.91E-32 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_04480 e2f280e93a916bd8fabd8ca5d1063a04 108 Pfam PF00581 Rhodanese-like domain 10 99 3.7E-12 T 14-10-2018 IPR001763 Rhodanese-like domain TSH58p_04480 e2f280e93a916bd8fabd8ca5d1063a04 108 Gene3D G3DSA:3.40.250.10 5 104 8.0E-25 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily TSH58p_04480 e2f280e93a916bd8fabd8ca5d1063a04 108 SUPERFAMILY SSF52821 7 105 4.85E-30 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily TSH58p_04480 e2f280e93a916bd8fabd8ca5d1063a04 108 SMART SM00450 8 103 6.6E-22 T 14-10-2018 IPR001763 Rhodanese-like domain TSH58p_23755 d2ea3162ca63dd6e5badab367ee3c11f 507 Pfam PF00665 Integrase core domain 127 253 5.0E-19 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 TSH58p_23755 d2ea3162ca63dd6e5badab367ee3c11f 507 SUPERFAMILY SSF53098 128 276 7.59E-8 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily TSH58p_23755 d2ea3162ca63dd6e5badab367ee3c11f 507 SUPERFAMILY SSF46689 3 85 6.81E-5 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_23755 d2ea3162ca63dd6e5badab367ee3c11f 507 Gene3D G3DSA:1.10.10.60 1 41 2.2E-5 T 14-10-2018 TSH58p_25730 e6318799300a16de1ff7d2390c800ac9 71 PIRSF PIRSF036704 1 70 1.8E-16 T 14-10-2018 IPR014177 Putative formate dehydrogenase, TAT signal-containing TSH58p_25730 e6318799300a16de1ff7d2390c800ac9 71 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 14 44 8.3E-4 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal TSH58p_25730 e6318799300a16de1ff7d2390c800ac9 71 TIGRFAM TIGR02811 formate_TAT: formate dehydrogenase region TAT target 11 67 1.1E-18 T 14-10-2018 IPR014177 Putative formate dehydrogenase, TAT signal-containing TSH58p_22800 0dd3e3459c0a9d8f62986b75937bbbfb 384 Gene3D G3DSA:1.10.150.130 81 185 4.5E-6 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal TSH58p_22800 0dd3e3459c0a9d8f62986b75937bbbfb 384 Pfam PF00589 Phage integrase family 189 362 9.0E-27 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TSH58p_22800 0dd3e3459c0a9d8f62986b75937bbbfb 384 SUPERFAMILY SSF56349 84 367 6.47E-52 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TSH58p_22800 0dd3e3459c0a9d8f62986b75937bbbfb 384 Gene3D G3DSA:1.10.443.10 186 377 2.1E-38 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TSH58p_09065 125212f16728f14a9d8e563c153d72a3 235 Pfam PF01292 Prokaryotic cytochrome b561 18 196 8.2E-20 T 14-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 TSH58p_09065 125212f16728f14a9d8e563c153d72a3 235 SUPERFAMILY SSF81342 13 200 1.18E-32 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 TSH58p_09065 125212f16728f14a9d8e563c153d72a3 235 Gene3D G3DSA:1.20.950.20 7 184 1.4E-16 T 14-10-2018 TSH58p_30495 91ca0505df59536b7992e1981ca2ec77 259 PIRSF PIRSF002854 2 259 1.6E-102 T 14-10-2018 IPR004872 Lipoprotein NlpA family TSH58p_30495 91ca0505df59536b7992e1981ca2ec77 259 Pfam PF03180 NLPA lipoprotein 24 259 1.8E-89 T 14-10-2018 IPR004872 Lipoprotein NlpA family TSH58p_30495 91ca0505df59536b7992e1981ca2ec77 259 Gene3D G3DSA:3.40.190.10 105 209 5.1E-94 T 14-10-2018 TSH58p_30495 91ca0505df59536b7992e1981ca2ec77 259 SUPERFAMILY SSF53850 23 259 2.95E-83 T 14-10-2018 TSH58p_30495 91ca0505df59536b7992e1981ca2ec77 259 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 19 259 1.9E-73 T 14-10-2018 IPR004872 Lipoprotein NlpA family TSH58p_30495 91ca0505df59536b7992e1981ca2ec77 259 Gene3D G3DSA:3.40.190.10 23 255 5.1E-94 T 14-10-2018 TSH58p_02850 8f59ab8fd67e67d3379995d2c5b57896 414 Gene3D G3DSA:3.40.50.2000 197 381 2.7E-59 T 14-10-2018 TSH58p_02850 8f59ab8fd67e67d3379995d2c5b57896 414 Pfam PF13439 Glycosyltransferase Family 4 19 198 5.3E-16 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TSH58p_02850 8f59ab8fd67e67d3379995d2c5b57896 414 Pfam PF00534 Glycosyl transferases group 1 223 380 2.4E-25 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 TSH58p_02850 8f59ab8fd67e67d3379995d2c5b57896 414 Gene3D G3DSA:3.40.50.2000 64 398 2.7E-59 T 14-10-2018 TSH58p_02850 8f59ab8fd67e67d3379995d2c5b57896 414 SUPERFAMILY SSF53756 6 403 3.84E-66 T 14-10-2018 TSH58p_03180 dcf9615d1f85cf8b5750d64616996625 255 Gene3D G3DSA:3.40.50.300 1 251 2.5E-62 T 14-10-2018 TSH58p_03180 dcf9615d1f85cf8b5750d64616996625 255 SMART SM00382 29 229 4.7E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_03180 dcf9615d1f85cf8b5750d64616996625 255 SUPERFAMILY SSF52540 4 251 4.57E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_03180 dcf9615d1f85cf8b5750d64616996625 255 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 230 252 4.7E-11 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSH58p_03180 dcf9615d1f85cf8b5750d64616996625 255 Pfam PF00005 ABC transporter 21 181 4.1E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_17995 56729cc0d1a889a64e29b7b148d82b45 275 Pfam PF09557 Domain of unknown function (DUF2382) 154 263 5.8E-23 T 14-10-2018 IPR019060 Domain of unknown function DUF2382 TSH58p_32530 6d018dcace0097e175ea02262b1e79e5 394 Gene3D G3DSA:3.40.50.2300 144 372 7.3E-113 T 14-10-2018 TSH58p_32530 6d018dcace0097e175ea02262b1e79e5 394 SUPERFAMILY SSF53822 27 372 2.62E-77 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_32530 6d018dcace0097e175ea02262b1e79e5 394 Gene3D G3DSA:3.40.50.2300 28 360 7.3E-113 T 14-10-2018 TSH58p_32530 6d018dcace0097e175ea02262b1e79e5 394 Pfam PF13458 Periplasmic binding protein 27 364 1.7E-63 T 14-10-2018 IPR028081 Leucine-binding protein domain TSH58p_04610 7c6894a17c4745f36e49adbd35dc9889 454 Pfam PF12831 FAD dependent oxidoreductase 8 442 1.3E-119 T 14-10-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal TSH58p_04610 7c6894a17c4745f36e49adbd35dc9889 454 SUPERFAMILY SSF51905 4 424 8.82E-25 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_04610 7c6894a17c4745f36e49adbd35dc9889 454 Gene3D G3DSA:3.50.50.60 4 202 1.6E-13 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_08390 ea693fbf553a62ae49c2377dc2082567 365 SUPERFAMILY SSF111369 50 274 1.83E-24 T 14-10-2018 TSH58p_08390 ea693fbf553a62ae49c2377dc2082567 365 Gene3D G3DSA:2.40.30.170 49 284 3.3E-67 T 14-10-2018 TSH58p_08390 ea693fbf553a62ae49c2377dc2082567 365 Gene3D G3DSA:1.10.287.470 94 159 3.3E-67 T 14-10-2018 TSH58p_08390 ea693fbf553a62ae49c2377dc2082567 365 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 48 268 1.3E-18 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain TSH58p_08390 ea693fbf553a62ae49c2377dc2082567 365 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 38 359 8.4E-75 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 TSH58p_08390 ea693fbf553a62ae49c2377dc2082567 365 Gene3D G3DSA:2.40.50.100 60 206 3.3E-67 T 14-10-2018 TSH58p_08390 ea693fbf553a62ae49c2377dc2082567 365 Gene3D G3DSA:2.40.420.20 285 357 3.3E-67 T 14-10-2018 TSH58p_18215 ba0dabfc3a8705557e895f604626ff65 276 SUPERFAMILY SSF53335 70 196 5.58E-13 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_18215 ba0dabfc3a8705557e895f604626ff65 276 Gene3D G3DSA:3.40.50.150 44 216 3.1E-12 T 14-10-2018 TSH58p_18215 ba0dabfc3a8705557e895f604626ff65 276 Pfam PF08241 Methyltransferase domain 133 176 5.5E-8 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TSH58p_13515 a56f3fe30f580be31935d1a0a769686a 294 Pfam PF00800 Prephenate dehydratase 7 183 6.3E-52 T 14-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 TSH58p_13515 a56f3fe30f580be31935d1a0a769686a 294 PIRSF PIRSF001500 2 283 5.0E-60 T 14-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 TSH58p_13515 a56f3fe30f580be31935d1a0a769686a 294 Gene3D G3DSA:3.40.190.10 89 170 8.2E-24 T 14-10-2018 TSH58p_13515 a56f3fe30f580be31935d1a0a769686a 294 Gene3D G3DSA:3.40.190.10 1 88 6.1E-27 T 14-10-2018 TSH58p_13515 a56f3fe30f580be31935d1a0a769686a 294 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 157 179 - T 14-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 TSH58p_13515 a56f3fe30f580be31935d1a0a769686a 294 Gene3D G3DSA:3.30.70.260 194 282 2.5E-18 T 14-10-2018 TSH58p_13515 a56f3fe30f580be31935d1a0a769686a 294 SUPERFAMILY SSF55021 176 280 1.6E-20 T 14-10-2018 TSH58p_13515 a56f3fe30f580be31935d1a0a769686a 294 SUPERFAMILY SSF53850 7 186 3.8E-55 T 14-10-2018 TSH58p_19240 37a900f5e156ee31cf649bd34db1cef8 130 Pfam PF07309 Flagellar protein FlaF 4 112 2.2E-31 T 14-10-2018 IPR010845 Flagellar FlaF GO:0044781 TSH58p_05530 443c91a5a742b2fe93fa453cbeccb9b4 301 Pfam PF13174 Tetratricopeptide repeat 252 282 7.5E-6 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_05530 443c91a5a742b2fe93fa453cbeccb9b4 301 SUPERFAMILY SSF48452 175 291 4.22E-14 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_05530 443c91a5a742b2fe93fa453cbeccb9b4 301 Gene3D G3DSA:1.25.40.10 176 298 1.0E-26 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_05530 443c91a5a742b2fe93fa453cbeccb9b4 301 Pfam PF13432 Tetratricopeptide repeat 181 246 4.1E-11 T 14-10-2018 TSH58p_05530 443c91a5a742b2fe93fa453cbeccb9b4 301 Hamap MF_02066 Cell division coordinator CpoB [cpoB]. 1 296 19.218 T 14-10-2018 IPR034706 Cell division coordinator CpoB GO:0051301 TSH58p_05530 443c91a5a742b2fe93fa453cbeccb9b4 301 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 176 291 4.8E-38 T 14-10-2018 IPR014162 Cell division coordinator CpoB, C-terminal TSH58p_06120 3517b94fbb2ceaf06be3e508aa96a5d5 310 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 284 2.8E-33 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_01655 e0df42ec0851ed08f0b39df13f0b925c 322 Gene3D G3DSA:3.40.50.1980 22 143 3.1E-20 T 14-10-2018 TSH58p_01655 e0df42ec0851ed08f0b39df13f0b925c 322 Pfam PF01497 Periplasmic binding protein 51 293 2.3E-24 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain TSH58p_01655 e0df42ec0851ed08f0b39df13f0b925c 322 Gene3D G3DSA:3.40.50.1980 147 317 1.7E-46 T 14-10-2018 TSH58p_01655 e0df42ec0851ed08f0b39df13f0b925c 322 SUPERFAMILY SSF53807 41 318 2.35E-44 T 14-10-2018 TSH58p_06410 18e968dba6a832e8bfe9d01429e3b0bb 125 Pfam PF13466 STAS domain 27 104 2.4E-14 T 14-10-2018 IPR002645 STAS domain TSH58p_06410 18e968dba6a832e8bfe9d01429e3b0bb 125 SUPERFAMILY SSF52091 26 105 1.92E-15 T 14-10-2018 IPR036513 STAS domain superfamily TSH58p_06410 18e968dba6a832e8bfe9d01429e3b0bb 125 Gene3D G3DSA:3.30.750.24 20 116 6.1E-17 T 14-10-2018 IPR036513 STAS domain superfamily TSH58p_11765 a3e818dea9242e9d4ffa50957ed80eaa 401 SUPERFAMILY SSF81345 28 284 1.31E-25 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_11765 a3e818dea9242e9d4ffa50957ed80eaa 401 Gene3D G3DSA:1.10.3470.10 74 290 3.4E-6 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_11765 a3e818dea9242e9d4ffa50957ed80eaa 401 Pfam PF00950 ABC 3 transport family 24 288 1.2E-55 T 14-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 TSH58p_04305 1b3e470e8d08b840e2464ba11cad18ae 340 SMART SM00062 35 265 3.9E-48 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_04305 1b3e470e8d08b840e2464ba11cad18ae 340 SUPERFAMILY SSF53850 26 256 8.28E-47 T 14-10-2018 TSH58p_04305 1b3e470e8d08b840e2464ba11cad18ae 340 Gene3D G3DSA:3.40.190.10 30 244 2.0E-50 T 14-10-2018 TSH58p_04305 1b3e470e8d08b840e2464ba11cad18ae 340 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 254 2.4E-27 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_04305 1b3e470e8d08b840e2464ba11cad18ae 340 Gene3D G3DSA:3.40.190.10 122 228 2.0E-50 T 14-10-2018 TSH58p_23735 445740c0924fe878a513f83bfb233b2a 84 Pfam PF13737 Transposase DDE domain 2 76 4.5E-14 T 14-10-2018 IPR025668 Transposase DDE domain TSH58p_24630 f22f1f46bf67c0473e3b257f6580d6e5 485 SUPERFAMILY SSF53720 6 483 2.09E-178 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSH58p_24630 f22f1f46bf67c0473e3b257f6580d6e5 485 Gene3D G3DSA:3.40.309.10 259 448 2.9E-188 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TSH58p_24630 f22f1f46bf67c0473e3b257f6580d6e5 485 Gene3D G3DSA:3.40.605.10 25 473 2.9E-188 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TSH58p_24630 f22f1f46bf67c0473e3b257f6580d6e5 485 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 30 477 2.1E-227 T 14-10-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 TSH58p_24630 f22f1f46bf67c0473e3b257f6580d6e5 485 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 283 294 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 TSH58p_24630 f22f1f46bf67c0473e3b257f6580d6e5 485 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 255 262 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 TSH58p_24630 f22f1f46bf67c0473e3b257f6580d6e5 485 Pfam PF00171 Aldehyde dehydrogenase family 19 478 8.6E-174 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TSH58p_32195 3f945467b82f9720f707033de4ed91e7 286 SUPERFAMILY SSF103481 191 283 1.96E-7 T 14-10-2018 TSH58p_32195 3f945467b82f9720f707033de4ed91e7 286 SUPERFAMILY SSF103481 42 141 2.35E-8 T 14-10-2018 TSH58p_32195 3f945467b82f9720f707033de4ed91e7 286 Pfam PF00892 EamA-like transporter family 7 136 7.8E-12 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_32195 3f945467b82f9720f707033de4ed91e7 286 Pfam PF00892 EamA-like transporter family 148 280 5.7E-11 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_11160 9afa7b12ed9c27ba23a355c510d20304 182 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 11 182 39.27 T 14-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 TSH58p_11160 9afa7b12ed9c27ba23a355c510d20304 182 Gene3D G3DSA:3.60.20.10 7 182 3.7E-67 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_11160 9afa7b12ed9c27ba23a355c510d20304 182 PIRSF PIRSF039093 5 182 5.5E-83 T 14-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 TSH58p_11160 9afa7b12ed9c27ba23a355c510d20304 182 SUPERFAMILY SSF56235 8 181 1.45E-56 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_11160 9afa7b12ed9c27ba23a355c510d20304 182 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 12 182 8.8E-82 T 14-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 TSH58p_11160 9afa7b12ed9c27ba23a355c510d20304 182 Pfam PF00227 Proteasome subunit 10 180 1.2E-19 T 14-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TSH58p_02490 50a2d0fbd8b146a37b65e6b61ffed6b9 325 Pfam PF13531 Bacterial extracellular solute-binding protein 86 322 1.2E-39 T 14-10-2018 TSH58p_02490 50a2d0fbd8b146a37b65e6b61ffed6b9 325 SUPERFAMILY SSF53850 84 325 2.79E-33 T 14-10-2018 TSH58p_02490 50a2d0fbd8b146a37b65e6b61ffed6b9 325 Gene3D G3DSA:3.40.190.10 87 322 2.3E-33 T 14-10-2018 TSH58p_02490 50a2d0fbd8b146a37b65e6b61ffed6b9 325 Gene3D G3DSA:3.40.190.10 161 286 2.3E-33 T 14-10-2018 TSH58p_06855 749073809853b326c8796810ab6bb1eb 279 Pfam PF09955 Predicted integral membrane protein (DUF2189) 89 212 6.3E-38 T 14-10-2018 IPR018692 Predicted integral membrane protein DUF2189 TSH58p_30990 eb918f74fd4fa0aabd34123446de417d 404 Pfam PF05940 NnrS protein 20 397 7.3E-69 T 14-10-2018 IPR010266 NnrS TSH58p_08545 b45aea578b383eac5dbb028d06036b42 233 Gene3D G3DSA:2.60.120.380 29 170 3.3E-8 T 14-10-2018 TSH58p_08545 b45aea578b383eac5dbb028d06036b42 233 SUPERFAMILY SSF89260 73 168 1.96E-5 T 14-10-2018 TSH58p_30575 8e823ca4e6360441de3c358750dc1b13 368 SMART SM00382 53 241 4.6E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_30575 8e823ca4e6360441de3c358750dc1b13 368 Gene3D G3DSA:3.40.50.300 25 261 2.4E-76 T 14-10-2018 TSH58p_30575 8e823ca4e6360441de3c358750dc1b13 368 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_30575 8e823ca4e6360441de3c358750dc1b13 368 SUPERFAMILY SSF55021 270 341 1.13E-5 T 14-10-2018 TSH58p_30575 8e823ca4e6360441de3c358750dc1b13 368 Pfam PF09383 NIL domain 292 341 9.4E-7 T 14-10-2018 IPR018449 NIL domain TSH58p_30575 8e823ca4e6360441de3c358750dc1b13 368 Gene3D G3DSA:3.30.70.260 262 364 2.4E-5 T 14-10-2018 TSH58p_30575 8e823ca4e6360441de3c358750dc1b13 368 SUPERFAMILY SSF52540 29 262 1.86E-78 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_30575 8e823ca4e6360441de3c358750dc1b13 368 Pfam PF00005 ABC transporter 44 192 4.6E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_10395 93f602196dc11459b5c28c4fccfea32c 347 PRINTS PR00069 Aldo-keto reductase signature 117 135 8.4E-10 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TSH58p_10395 93f602196dc11459b5c28c4fccfea32c 347 PRINTS PR00069 Aldo-keto reductase signature 165 182 8.4E-10 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TSH58p_10395 93f602196dc11459b5c28c4fccfea32c 347 Gene3D G3DSA:3.20.20.100 1 347 4.0E-131 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TSH58p_10395 93f602196dc11459b5c28c4fccfea32c 347 SUPERFAMILY SSF51430 1 347 2.49E-110 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TSH58p_10395 93f602196dc11459b5c28c4fccfea32c 347 Pfam PF00248 Aldo/keto reductase family 16 339 1.4E-74 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain TSH58p_19270 9f44c478080c5b830f9086a6d1d5d668 310 Pfam PF00294 pfkB family carbohydrate kinase 7 300 1.2E-51 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB TSH58p_19270 9f44c478080c5b830f9086a6d1d5d668 310 SUPERFAMILY SSF53613 7 302 5.77E-76 T 14-10-2018 IPR029056 Ribokinase-like TSH58p_19270 9f44c478080c5b830f9086a6d1d5d668 310 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 255 268 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TSH58p_19270 9f44c478080c5b830f9086a6d1d5d668 310 Gene3D G3DSA:3.40.1190.20 4 307 2.9E-79 T 14-10-2018 IPR029056 Ribokinase-like TSH58p_24995 5eb40c5bd812fd85a416f5543fdbe5db 170 Pfam PF02566 OsmC-like protein 62 164 4.8E-17 T 14-10-2018 IPR003718 OsmC/Ohr family TSH58p_24995 5eb40c5bd812fd85a416f5543fdbe5db 170 Gene3D G3DSA:3.30.300.20 3 157 1.7E-35 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta TSH58p_24995 5eb40c5bd812fd85a416f5543fdbe5db 170 SUPERFAMILY SSF82784 8 167 9.68E-35 T 14-10-2018 IPR036102 OsmC/Ohr superfamily TSH58p_08560 84fb88a378fc7ac9cf891eca6c406b19 249 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 33 247 3.0E-28 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_08560 84fb88a378fc7ac9cf891eca6c406b19 249 Gene3D G3DSA:3.40.190.10 34 247 9.2E-32 T 14-10-2018 TSH58p_08560 84fb88a378fc7ac9cf891eca6c406b19 249 Gene3D G3DSA:3.40.190.10 115 209 9.2E-32 T 14-10-2018 TSH58p_08560 84fb88a378fc7ac9cf891eca6c406b19 249 SUPERFAMILY SSF53850 31 247 2.35E-36 T 14-10-2018 TSH58p_08560 84fb88a378fc7ac9cf891eca6c406b19 249 SMART SM00062 31 249 3.7E-4 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_17250 b1611003a64efc39ff5848585f146f62 154 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 147 9.1E-54 T 14-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 TSH58p_17250 b1611003a64efc39ff5848585f146f62 154 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 86.107 T 14-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 TSH58p_17250 b1611003a64efc39ff5848585f146f62 154 Pfam PF03477 ATP cone domain 50 136 9.0E-16 T 14-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 TSH58p_32120 65886b8d261a1ae0807b08455a1b5c74 399 Pfam PF00872 Transposase, Mutator family 3 371 6.4E-131 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 TSH58p_26430 bd4359ec240f3efa69652877ea67fc49 266 SUPERFAMILY SSF52172 126 256 1.38E-28 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_26430 bd4359ec240f3efa69652877ea67fc49 266 Pfam PF00072 Response regulator receiver domain 129 238 8.0E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_26430 bd4359ec240f3efa69652877ea67fc49 266 Gene3D G3DSA:3.40.50.12740 126 263 4.2E-28 T 14-10-2018 TSH58p_26430 bd4359ec240f3efa69652877ea67fc49 266 SMART SM00448 127 242 4.3E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_27745 22b86368be9b5623b57bca677040e175 156 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 19 144 5.1E-29 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ TSH58p_26750 2ef64f08a40bf4267280f3798eaa822d 263 SUPERFAMILY SSF51735 8 243 4.21E-53 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_26750 2ef64f08a40bf4267280f3798eaa822d 263 PIRSF PIRSF000126 1 259 2.7E-51 T 14-10-2018 TSH58p_26750 2ef64f08a40bf4267280f3798eaa822d 263 Gene3D G3DSA:3.40.50.720 9 248 1.1E-54 T 14-10-2018 TSH58p_26750 2ef64f08a40bf4267280f3798eaa822d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 9.3E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_26750 2ef64f08a40bf4267280f3798eaa822d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 9.3E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_26750 2ef64f08a40bf4267280f3798eaa822d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 9.3E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_26750 2ef64f08a40bf4267280f3798eaa822d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 9.3E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_26750 2ef64f08a40bf4267280f3798eaa822d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 9.3E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_26750 2ef64f08a40bf4267280f3798eaa822d 263 Pfam PF00106 short chain dehydrogenase 10 193 2.2E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_26750 2ef64f08a40bf4267280f3798eaa822d 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSH58p_26750 2ef64f08a40bf4267280f3798eaa822d 263 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 188 0.0091 T 14-10-2018 TSH58p_15825 3f14bee19a708d0c37b4e4268ca6773d 360 Pfam PF01594 AI-2E family transporter 42 340 1.2E-45 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like TSH58p_26785 5349790b9cddb82d3dca833e71d64b08 251 SUPERFAMILY SSF52266 51 238 6.26E-38 T 14-10-2018 TSH58p_26785 5349790b9cddb82d3dca833e71d64b08 251 Gene3D G3DSA:3.40.50.1110 49 239 1.1E-36 T 14-10-2018 IPR036514 SGNH hydrolase superfamily TSH58p_26785 5349790b9cddb82d3dca833e71d64b08 251 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 56 228 1.4E-19 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain TSH58p_21045 a5dfd041d4d4b0ffb3462c9f9a8283d4 616 SUPERFAMILY SSF52794 132 226 4.88E-36 T 14-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 TSH58p_21045 a5dfd041d4d4b0ffb3462c9f9a8283d4 616 SUPERFAMILY SSF52794 3 100 2.62E-33 T 14-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 TSH58p_21045 a5dfd041d4d4b0ffb3462c9f9a8283d4 616 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 6 94 1.5E-17 T 14-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TSH58p_21045 a5dfd041d4d4b0ffb3462c9f9a8283d4 616 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 134 223 2.3E-16 T 14-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TSH58p_21045 a5dfd041d4d4b0ffb3462c9f9a8283d4 616 Pfam PF02378 Phosphotransferase system, EIIC 267 530 9.9E-21 T 14-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 TSH58p_21045 a5dfd041d4d4b0ffb3462c9f9a8283d4 616 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 133 216 1.8E-36 T 14-10-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202 TSH58p_21045 a5dfd041d4d4b0ffb3462c9f9a8283d4 616 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 5 87 5.6E-31 T 14-10-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202 TSH58p_21045 a5dfd041d4d4b0ffb3462c9f9a8283d4 616 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 251 585 5.1E-137 T 14-10-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 TSH58p_21045 a5dfd041d4d4b0ffb3462c9f9a8283d4 616 Gene3D G3DSA:3.40.50.2300 125 230 3.1E-40 T 14-10-2018 TSH58p_21045 a5dfd041d4d4b0ffb3462c9f9a8283d4 616 Gene3D G3DSA:3.40.50.2300 1 101 2.9E-37 T 14-10-2018 TSH58p_20380 68da4fa09aed85ac5052f17ead40820b 642 SUPERFAMILY SSF53448 63 181 6.86E-5 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_20380 68da4fa09aed85ac5052f17ead40820b 642 SUPERFAMILY SSF53756 346 615 7.22E-23 T 14-10-2018 TSH58p_20380 68da4fa09aed85ac5052f17ead40820b 642 Gene3D G3DSA:3.40.50.2000 533 624 9.8E-9 T 14-10-2018 TSH58p_20380 68da4fa09aed85ac5052f17ead40820b 642 Gene3D G3DSA:3.40.50.2000 343 483 8.1E-7 T 14-10-2018 TSH58p_08730 5a26b18d31a72b3d5b0985159f98e687 391 SUPERFAMILY SSF103473 6 386 1.18E-26 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_08730 5a26b18d31a72b3d5b0985159f98e687 391 Gene3D G3DSA:1.20.1250.20 1 384 2.0E-21 T 14-10-2018 TSH58p_12290 4c4fb3e3b925d9bf6437bc8f55cf165b 405 Gene3D G3DSA:3.40.50.1100 18 214 3.4E-186 T 14-10-2018 TSH58p_12290 4c4fb3e3b925d9bf6437bc8f55cf165b 405 Gene3D G3DSA:3.40.50.1100 62 394 3.4E-186 T 14-10-2018 TSH58p_12290 4c4fb3e3b925d9bf6437bc8f55cf165b 405 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 89 103 - T 14-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TSH58p_12290 4c4fb3e3b925d9bf6437bc8f55cf165b 405 SUPERFAMILY SSF53686 11 399 4.32E-149 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TSH58p_12290 4c4fb3e3b925d9bf6437bc8f55cf165b 405 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 15 400 5.0E-192 T 14-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TSH58p_12290 4c4fb3e3b925d9bf6437bc8f55cf165b 405 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 10 401 53.235 T 14-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TSH58p_12290 4c4fb3e3b925d9bf6437bc8f55cf165b 405 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 60 388 2.9E-48 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TSH58p_12290 4c4fb3e3b925d9bf6437bc8f55cf165b 405 PIRSF PIRSF001413 6 405 1.8E-162 T 14-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TSH58p_20050 8b52759132363ea9ef0844b3ea19b4eb 90 Pfam PF11747 Killing trait 11 78 2.7E-30 T 14-10-2018 IPR021070 Killing trait, RebB TSH58p_06645 67e0ca45e6e4c93b1af4470e71a782b4 95 Pfam PF07045 Domain of unknown function (DUF1330) 2 94 1.9E-35 T 14-10-2018 IPR010753 Domain of unknown function DUF1330 TSH58p_06645 67e0ca45e6e4c93b1af4470e71a782b4 95 SUPERFAMILY SSF54909 1 94 1.17E-30 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel TSH58p_06645 67e0ca45e6e4c93b1af4470e71a782b4 95 Gene3D G3DSA:3.30.70.100 1 95 1.5E-33 T 14-10-2018 TSH58p_22075 9972a5108cb9ef13881b5adb39f3b788 143 TIGRFAM TIGR01841 phasin: phasin family protein 50 137 4.1E-23 T 14-10-2018 IPR010127 Phasin, subfamily 1 TSH58p_22075 9972a5108cb9ef13881b5adb39f3b788 143 Pfam PF09361 Phasin protein 30 129 7.6E-22 T 14-10-2018 IPR018968 Phasin TSH58p_31515 018bae0c2f86371c499c6769f0fb818a 291 Gene3D G3DSA:3.60.130.10 4 288 4.6E-83 T 14-10-2018 TSH58p_31515 018bae0c2f86371c499c6769f0fb818a 291 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 8 277 4.5E-63 T 14-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 TSH58p_31515 018bae0c2f86371c499c6769f0fb818a 291 SUPERFAMILY SSF51197 6 280 4.4E-77 T 14-10-2018 TSH58p_01520 accedfbee0851aabaf15d8d16e3cad2a 279 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 260 7.6E-47 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_01520 accedfbee0851aabaf15d8d16e3cad2a 279 SUPERFAMILY SSF53850 11 261 9.59E-51 T 14-10-2018 TSH58p_01520 accedfbee0851aabaf15d8d16e3cad2a 279 Gene3D G3DSA:3.40.190.10 36 258 2.4E-54 T 14-10-2018 TSH58p_01520 accedfbee0851aabaf15d8d16e3cad2a 279 SMART SM00062 38 263 1.6E-39 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_01520 accedfbee0851aabaf15d8d16e3cad2a 279 Gene3D G3DSA:3.40.190.10 125 221 2.4E-54 T 14-10-2018 TSH58p_26080 87c6a74f196eb9b1db0fadda6dcf9678 763 SUPERFAMILY SSF56935 50 763 9.17E-115 T 14-10-2018 TSH58p_26080 87c6a74f196eb9b1db0fadda6dcf9678 763 Pfam PF07715 TonB-dependent Receptor Plug Domain 87 187 2.3E-15 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain TSH58p_26080 87c6a74f196eb9b1db0fadda6dcf9678 763 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 89 763 3.3E-80 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 TSH58p_26080 87c6a74f196eb9b1db0fadda6dcf9678 763 Gene3D G3DSA:2.170.130.10 71 198 1.4E-29 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily TSH58p_26080 87c6a74f196eb9b1db0fadda6dcf9678 763 Gene3D G3DSA:2.40.170.20 201 763 6.6E-114 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily TSH58p_26080 87c6a74f196eb9b1db0fadda6dcf9678 763 Pfam PF00593 TonB dependent receptor 288 761 8.0E-49 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel TSH58p_07605 cb4e4306c7ae71f79a4396658b5469da 208 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 1 203 33.777 T 14-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 TSH58p_07605 cb4e4306c7ae71f79a4396658b5469da 208 SUPERFAMILY SSF52218 1 204 3.52E-58 T 14-10-2018 IPR029039 Flavoprotein-like superfamily TSH58p_07605 cb4e4306c7ae71f79a4396658b5469da 208 Pfam PF02525 Flavodoxin-like fold 1 201 1.6E-49 T 14-10-2018 IPR003680 Flavodoxin-like fold TSH58p_07605 cb4e4306c7ae71f79a4396658b5469da 208 Gene3D G3DSA:3.40.50.360 1 204 7.3E-63 T 14-10-2018 IPR029039 Flavoprotein-like superfamily TSH58p_15365 1841df52d44a1985bf28ae653a819fcb 689 Pfam PF02120 Flagellar hook-length control protein FliK 561 644 1.4E-16 T 14-10-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal TSH58p_15365 1841df52d44a1985bf28ae653a819fcb 689 Gene3D G3DSA:3.30.750.140 539 655 3.3E-11 T 14-10-2018 IPR038610 FliK-like, C-terminal domain superfamily TSH58p_14405 22bc70f843c00abb4ae725260bd7c6c3 1202 Pfam PF01968 Hydantoinase/oxoprolinase 209 496 7.5E-115 T 14-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 TSH58p_14405 22bc70f843c00abb4ae725260bd7c6c3 1202 Pfam PF02538 Hydantoinase B/oxoprolinase 695 1199 1.6E-212 T 14-10-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 TSH58p_14405 22bc70f843c00abb4ae725260bd7c6c3 1202 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 11 190 1.2E-59 T 14-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 TSH58p_31860 708d383dad3c5f9cb1da1a83ede29e07 464 Gene3D G3DSA:2.30.170.30 1 54 6.9E-21 T 14-10-2018 TSH58p_31860 708d383dad3c5f9cb1da1a83ede29e07 464 PIRSF PIRSF018788 1 456 1.1E-232 T 14-10-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 TSH58p_31860 708d383dad3c5f9cb1da1a83ede29e07 464 Gene3D G3DSA:1.10.220.70 55 141 6.8E-32 T 14-10-2018 TSH58p_31860 708d383dad3c5f9cb1da1a83ede29e07 464 Gene3D G3DSA:3.20.20.70 142 453 3.5E-148 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_31860 708d383dad3c5f9cb1da1a83ede29e07 464 Pfam PF06751 Ethanolamine ammonia lyase large subunit (EutB) 12 445 1.6E-217 T 14-10-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 TSH58p_19860 864ca1cbba3c0d0db266a3f7482d2d31 254 SUPERFAMILY SSF51735 6 251 5.79E-77 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_19860 864ca1cbba3c0d0db266a3f7482d2d31 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 251 3.2E-58 T 14-10-2018 TSH58p_19860 864ca1cbba3c0d0db266a3f7482d2d31 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.1E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_19860 864ca1cbba3c0d0db266a3f7482d2d31 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.1E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_19860 864ca1cbba3c0d0db266a3f7482d2d31 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.1E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_19860 864ca1cbba3c0d0db266a3f7482d2d31 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.1E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_19860 864ca1cbba3c0d0db266a3f7482d2d31 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.1E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_19860 864ca1cbba3c0d0db266a3f7482d2d31 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.1E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_19860 864ca1cbba3c0d0db266a3f7482d2d31 254 Gene3D G3DSA:3.40.50.720 1 253 2.6E-80 T 14-10-2018 TSH58p_14385 430f2416dd80743059f56713cbae94aa 292 Pfam PF00892 EamA-like transporter family 141 277 1.3E-14 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_14385 430f2416dd80743059f56713cbae94aa 292 Pfam PF00892 EamA-like transporter family 7 129 6.8E-18 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_14385 430f2416dd80743059f56713cbae94aa 292 SUPERFAMILY SSF103481 183 280 5.1E-11 T 14-10-2018 TSH58p_14385 430f2416dd80743059f56713cbae94aa 292 SUPERFAMILY SSF103481 37 133 5.49E-13 T 14-10-2018 TSH58p_05585 b11c029f3cda199e40fb7f2301c9689a 542 Gene3D G3DSA:3.40.50.300 1 285 3.3E-122 T 14-10-2018 TSH58p_05585 b11c029f3cda199e40fb7f2301c9689a 542 Hamap MF_01227 CTP synthase [pyrG]. 2 539 50.708 T 14-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TSH58p_05585 b11c029f3cda199e40fb7f2301c9689a 542 TIGRFAM TIGR00337 PyrG: CTP synthase 2 534 6.5E-226 T 14-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TSH58p_05585 b11c029f3cda199e40fb7f2301c9689a 542 SUPERFAMILY SSF52317 289 538 1.05E-79 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_05585 b11c029f3cda199e40fb7f2301c9689a 542 Pfam PF06418 CTP synthase N-terminus 3 264 3.7E-119 T 14-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TSH58p_05585 b11c029f3cda199e40fb7f2301c9689a 542 Gene3D G3DSA:3.40.50.880 286 541 3.0E-97 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_05585 b11c029f3cda199e40fb7f2301c9689a 542 Pfam PF00117 Glutamine amidotransferase class-I 301 534 1.5E-56 T 14-10-2018 IPR017926 Glutamine amidotransferase TSH58p_05585 b11c029f3cda199e40fb7f2301c9689a 542 SUPERFAMILY SSF52540 1 266 4.13E-118 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_14495 5a49bc2d11cac3af8470bbd621b30e72 565 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 47 63 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TSH58p_14495 5a49bc2d11cac3af8470bbd621b30e72 565 Pfam PF00682 HMGL-like 41 318 1.5E-75 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 TSH58p_14495 5a49bc2d11cac3af8470bbd621b30e72 565 SUPERFAMILY SSF51569 29 337 3.3E-98 T 14-10-2018 TSH58p_14495 5a49bc2d11cac3af8470bbd621b30e72 565 Pfam PF08502 LeuA allosteric (dimerisation) domain 431 563 1.4E-29 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TSH58p_14495 5a49bc2d11cac3af8470bbd621b30e72 565 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 250 263 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TSH58p_14495 5a49bc2d11cac3af8470bbd621b30e72 565 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 16 565 2.0E-239 T 14-10-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TSH58p_14495 5a49bc2d11cac3af8470bbd621b30e72 565 Gene3D G3DSA:3.30.160.270 386 563 1.2E-62 T 14-10-2018 TSH58p_14495 5a49bc2d11cac3af8470bbd621b30e72 565 SUPERFAMILY SSF110921 456 563 6.8E-36 T 14-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TSH58p_14495 5a49bc2d11cac3af8470bbd621b30e72 565 SMART SM00917 431 564 8.0E-36 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TSH58p_14495 5a49bc2d11cac3af8470bbd621b30e72 565 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 12 565 53.863 T 14-10-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TSH58p_14495 5a49bc2d11cac3af8470bbd621b30e72 565 Gene3D G3DSA:3.20.20.70 19 385 3.4E-150 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_14495 5a49bc2d11cac3af8470bbd621b30e72 565 SUPERFAMILY SSF89000 397 447 1.1E-15 T 14-10-2018 TSH58p_31015 3635fe93148180c014d59c1804eefc82 264 Pfam PF00378 Enoyl-CoA hydratase/isomerase 21 234 9.2E-29 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TSH58p_31015 3635fe93148180c014d59c1804eefc82 264 Gene3D G3DSA:3.90.226.10 13 264 2.5E-57 T 14-10-2018 TSH58p_31015 3635fe93148180c014d59c1804eefc82 264 SUPERFAMILY SSF52096 18 263 3.32E-54 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_24785 49a7e9ed5333612c022536fade5b0e8e 430 Pfam PF00805 Pentapeptide repeats (8 copies) 41 72 8.3E-6 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_24785 49a7e9ed5333612c022536fade5b0e8e 430 Pfam PF00805 Pentapeptide repeats (8 copies) 319 347 3.0E-5 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_24785 49a7e9ed5333612c022536fade5b0e8e 430 Pfam PF00805 Pentapeptide repeats (8 copies) 80 118 1.6E-9 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_24785 49a7e9ed5333612c022536fade5b0e8e 430 Pfam PF00805 Pentapeptide repeats (8 copies) 166 204 3.9E-12 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_24785 49a7e9ed5333612c022536fade5b0e8e 430 Pfam PF00805 Pentapeptide repeats (8 copies) 380 413 1.8E-8 T 14-10-2018 IPR001646 Pentapeptide repeat TSH58p_24785 49a7e9ed5333612c022536fade5b0e8e 430 SUPERFAMILY SSF141571 20 123 3.53E-19 T 14-10-2018 TSH58p_24785 49a7e9ed5333612c022536fade5b0e8e 430 Gene3D G3DSA:2.160.20.80 2 118 1.1E-20 T 14-10-2018 TSH58p_24785 49a7e9ed5333612c022536fade5b0e8e 430 SUPERFAMILY SSF141571 269 418 1.28E-29 T 14-10-2018 TSH58p_24785 49a7e9ed5333612c022536fade5b0e8e 430 Gene3D G3DSA:2.160.20.80 252 429 5.2E-34 T 14-10-2018 TSH58p_24785 49a7e9ed5333612c022536fade5b0e8e 430 Gene3D G3DSA:2.160.20.80 134 239 2.2E-25 T 14-10-2018 TSH58p_24785 49a7e9ed5333612c022536fade5b0e8e 430 SUPERFAMILY SSF141571 143 232 3.4E-24 T 14-10-2018 TSH58p_20490 3a6b8de9d97d5bdbdd046cba5c9ed3d0 63 Gene3D G3DSA:2.60.260.40 2 53 2.6E-20 T 14-10-2018 TSH58p_20490 3a6b8de9d97d5bdbdd046cba5c9ed3d0 63 ProDom PD007270 C CYTOCHROME OXIDASE MEMBRANE VB SUBUNIT POLYPEPTIDE MITOCHONDRION OXIDOREDUCTASE INNER 17 52 0.007 T 14-10-2018 IPR002124 Cytochrome c oxidase, subunit Vb GO:0004129|GO:0005740 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_20490 3a6b8de9d97d5bdbdd046cba5c9ed3d0 63 Pfam PF10276 Zinc-finger domain 16 50 9.6E-17 T 14-10-2018 IPR019401 Zinc finger, CHCC-type Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_19735 8de5c9890114c508558c3c9774f1c074 285 Gene3D G3DSA:3.90.1530.30 53 115 4.3E-20 T 14-10-2018 TSH58p_19735 8de5c9890114c508558c3c9774f1c074 285 SUPERFAMILY SSF110849 36 132 7.5E-21 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily TSH58p_19735 8de5c9890114c508558c3c9774f1c074 285 SMART SM00470 40 128 5.2E-27 T 14-10-2018 IPR003115 ParB/Sulfiredoxin TSH58p_19735 8de5c9890114c508558c3c9774f1c074 285 SUPERFAMILY SSF109709 121 229 4.19E-21 T 14-10-2018 TSH58p_19735 8de5c9890114c508558c3c9774f1c074 285 Pfam PF02195 ParB-like nuclease domain 42 127 1.3E-18 T 14-10-2018 IPR003115 ParB/Sulfiredoxin TSH58p_19735 8de5c9890114c508558c3c9774f1c074 285 Gene3D G3DSA:1.10.10.2830 116 230 4.2E-21 T 14-10-2018 TSH58p_19735 8de5c9890114c508558c3c9774f1c074 285 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 39 186 1.2E-34 T 14-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 TSH58p_04295 8d05fdaec5f6ba284ebc1026a75e7af8 144 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 44 117 3.5E-35 T 14-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 TSH58p_04295 8d05fdaec5f6ba284ebc1026a75e7af8 144 Gene3D G3DSA:3.10.20.400 12 108 2.6E-39 T 14-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 TSH58p_04295 8d05fdaec5f6ba284ebc1026a75e7af8 144 SUPERFAMILY SSF141734 20 129 6.28E-48 T 14-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 TSH58p_04295 8d05fdaec5f6ba284ebc1026a75e7af8 144 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 18 121 31.876 T 14-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 TSH58p_04295 8d05fdaec5f6ba284ebc1026a75e7af8 144 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 67 120 3.0E-17 T 14-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 TSH58p_02800 ae3d02f07f7a2d07f3721db08a9439a7 421 SUPERFAMILY SSF53756 36 407 2.37E-42 T 14-10-2018 TSH58p_02800 ae3d02f07f7a2d07f3721db08a9439a7 421 Gene3D G3DSA:3.40.50.2000 17 213 4.0E-5 T 14-10-2018 TSH58p_02800 ae3d02f07f7a2d07f3721db08a9439a7 421 Gene3D G3DSA:3.40.50.2000 230 406 2.6E-29 T 14-10-2018 TSH58p_02800 ae3d02f07f7a2d07f3721db08a9439a7 421 Pfam PF00534 Glycosyl transferases group 1 244 379 1.0E-18 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 TSH58p_24180 daa089ce9e857a691a5553a3408f0eba 241 SUPERFAMILY SSF52540 4 237 3.3E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_24180 daa089ce9e857a691a5553a3408f0eba 241 SMART SM00382 29 215 1.3E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_24180 daa089ce9e857a691a5553a3408f0eba 241 Pfam PF00005 ABC transporter 21 164 2.7E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_24180 daa089ce9e857a691a5553a3408f0eba 241 Gene3D G3DSA:3.40.50.300 1 238 1.3E-59 T 14-10-2018 TSH58p_24180 daa089ce9e857a691a5553a3408f0eba 241 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 215 237 6.2E-10 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSH58p_25970 0db69d3bdbc8765f35adc205d87c3177 295 SUPERFAMILY SSF51197 57 274 1.28E-16 T 14-10-2018 TSH58p_25970 0db69d3bdbc8765f35adc205d87c3177 295 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 60 250 1.2E-5 T 14-10-2018 IPR008775 Phytanoyl-CoA dioxygenase TSH58p_25970 0db69d3bdbc8765f35adc205d87c3177 295 Gene3D G3DSA:2.60.120.620 40 273 3.2E-12 T 14-10-2018 TSH58p_04440 bf889ce69a73d8f827854bd9aa585193 728 Gene3D G3DSA:1.10.530.10 190 365 2.1E-28 T 14-10-2018 TSH58p_22290 408e39acbadd4eb0876a8891be2a1be8 288 Pfam PF02012 BNR/Asp-box repeat 149 159 0.11 T 14-10-2018 IPR002860 BNR repeat TSH58p_22290 408e39acbadd4eb0876a8891be2a1be8 288 Gene3D G3DSA:2.130.10.10 31 284 4.9E-32 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TSH58p_22290 408e39acbadd4eb0876a8891be2a1be8 288 SUPERFAMILY SSF110296 36 286 2.88E-40 T 14-10-2018 TSH58p_14165 897826d11526cb38f17764e39e61e4e7 385 Pfam PF11294 Protein of unknown function (DUF3095) 3 375 8.9E-96 T 14-10-2018 IPR021445 Protein of unknown function DUF3095 TSH58p_02590 e4dafb08f8106d0dca3a21e10d6622fe 131 TIGRFAM TIGR02847 CyoD: cytochrome o ubiquinol oxidase subunit IV 26 122 6.6E-35 T 14-10-2018 IPR014210 Cytochrome o ubiquinol oxidase subunit IV GO:0008827|GO:0015990|GO:0016021 TSH58p_02590 e4dafb08f8106d0dca3a21e10d6622fe 131 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 33 106 3.6E-18 T 14-10-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 TSH58p_23375 7e0700ff066b82a7ccb056b9468deb8b 598 Pfam PF05947 Type VI secretion system, TssF 7 596 1.4E-188 T 14-10-2018 IPR010272 Type VI secretion system, TssF-like TSH58p_23375 7e0700ff066b82a7ccb056b9468deb8b 598 PIRSF PIRSF028304 2 597 4.8E-168 T 14-10-2018 IPR010272 Type VI secretion system, TssF-like TSH58p_23375 7e0700ff066b82a7ccb056b9468deb8b 598 TIGRFAM TIGR03359 VI_chp_6: type VI secretion protein, TIGR03359 family 6 598 2.5E-176 T 14-10-2018 IPR010272 Type VI secretion system, TssF-like TSH58p_29410 a1f1b2551d0e3b820b902e99297824ff 217 Pfam PF01618 MotA/TolQ/ExbB proton channel family 87 169 2.7E-5 T 14-10-2018 IPR002898 MotA/TolQ/ExbB proton channel TSH58p_08680 299df4f8cc30b7493b959a3bbfefa20a 259 SUPERFAMILY SSF102712 150 225 3.66E-6 T 14-10-2018 TSH58p_08680 299df4f8cc30b7493b959a3bbfefa20a 259 TIGRFAM TIGR00608 radc: DNA repair protein RadC 44 258 6.4E-65 T 14-10-2018 IPR001405 Uncharacterised protein family UPF0758 TSH58p_08680 299df4f8cc30b7493b959a3bbfefa20a 259 Pfam PF04002 RadC-like JAB domain 139 257 2.7E-44 T 14-10-2018 IPR025657 RadC-like JAB domain TSH58p_08680 299df4f8cc30b7493b959a3bbfefa20a 259 Gene3D G3DSA:3.40.140.10 137 259 5.1E-42 T 14-10-2018 TSH58p_08680 299df4f8cc30b7493b959a3bbfefa20a 259 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 208 213 - T 14-10-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site TSH58p_22850 6a8e4a294cf3f9017c5814b6c7366a88 83 Pfam PF06906 Protein of unknown function (DUF1272) 2 58 6.6E-30 T 14-10-2018 IPR010696 Protein of unknown function DUF1272 TSH58p_22850 6a8e4a294cf3f9017c5814b6c7366a88 83 SUPERFAMILY SSF144206 28 55 3.92E-5 T 14-10-2018 IPR036283 NOB1 zinc finger-like superfamily Reactome: R-HSA-6791226 TSH58p_31620 c620b03883d2f6ec4a13a0f0369b8b03 273 Pfam PF00005 ABC transporter 17 173 1.4E-22 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_31620 c620b03883d2f6ec4a13a0f0369b8b03 273 Gene3D G3DSA:3.40.50.300 4 236 1.1E-55 T 14-10-2018 TSH58p_31620 c620b03883d2f6ec4a13a0f0369b8b03 273 SUPERFAMILY SSF52540 2 230 4.26E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_31620 c620b03883d2f6ec4a13a0f0369b8b03 273 SMART SM00382 26 230 1.5E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_31620 c620b03883d2f6ec4a13a0f0369b8b03 273 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_13690 39342d1b9cfe138705a274c7bc158315 473 SMART SM00228 99 170 2.3E-15 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_13690 39342d1b9cfe138705a274c7bc158315 473 SUPERFAMILY SSF50156 87 182 8.39E-21 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 TSH58p_13690 39342d1b9cfe138705a274c7bc158315 473 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 51 368 2.6E-104 T 14-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 TSH58p_13690 39342d1b9cfe138705a274c7bc158315 473 Pfam PF13180 PDZ domain 99 179 3.3E-12 T 14-10-2018 IPR001478 PDZ domain GO:0005515 TSH58p_13690 39342d1b9cfe138705a274c7bc158315 473 Pfam PF03572 Peptidase family S41 196 362 4.6E-58 T 14-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 TSH58p_13690 39342d1b9cfe138705a274c7bc158315 473 Gene3D G3DSA:3.90.226.10 187 360 8.8E-102 T 14-10-2018 TSH58p_13690 39342d1b9cfe138705a274c7bc158315 473 Gene3D G3DSA:2.30.42.10 99 186 8.8E-102 T 14-10-2018 TSH58p_13690 39342d1b9cfe138705a274c7bc158315 473 SUPERFAMILY SSF52096 27 367 1.09E-86 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_13690 39342d1b9cfe138705a274c7bc158315 473 Gene3D G3DSA:3.30.750.44 35 338 8.8E-102 T 14-10-2018 TSH58p_13690 39342d1b9cfe138705a274c7bc158315 473 SMART SM00245 172 363 8.1E-79 T 14-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 TSH58p_09195 e0425fd0242b27e6f12b912388f4676d 357 Pfam PF01180 Dihydroorotate dehydrogenase 44 340 1.6E-93 T 14-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 TSH58p_09195 e0425fd0242b27e6f12b912388f4676d 357 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 9 357 1.4E-124 T 14-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 TSH58p_09195 e0425fd0242b27e6f12b912388f4676d 357 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 292 312 - T 14-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 TSH58p_09195 e0425fd0242b27e6f12b912388f4676d 357 SUPERFAMILY SSF51395 7 356 2.08E-111 T 14-10-2018 TSH58p_09195 e0425fd0242b27e6f12b912388f4676d 357 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 4 336 42.906 T 14-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 TSH58p_09195 e0425fd0242b27e6f12b912388f4676d 357 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 79 98 - T 14-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 TSH58p_09195 e0425fd0242b27e6f12b912388f4676d 357 Gene3D G3DSA:3.20.20.70 5 357 8.1E-148 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_08510 d2587422dd700a2205b064d405c3336c 301 Gene3D G3DSA:1.20.1330.10 46 296 1.1E-12 T 14-10-2018 TSH58p_08510 d2587422dd700a2205b064d405c3336c 301 Pfam PF00700 Bacterial flagellin C-terminal helical region 220 300 6.0E-10 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 TSH58p_08510 d2587422dd700a2205b064d405c3336c 301 SUPERFAMILY SSF64518 1 301 1.83E-30 T 14-10-2018 TSH58p_08510 d2587422dd700a2205b064d405c3336c 301 Pfam PF00669 Bacterial flagellin N-terminal helical region 6 138 2.8E-10 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 TSH58p_27485 8c984f0006b2ba58357dbe154e50c411 128 PRINTS PR00604 Class IA and IB cytochrome C signature 116 124 5.3E-14 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_27485 8c984f0006b2ba58357dbe154e50c411 128 PRINTS PR00604 Class IA and IB cytochrome C signature 49 64 5.3E-14 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_27485 8c984f0006b2ba58357dbe154e50c411 128 PRINTS PR00604 Class IA and IB cytochrome C signature 99 109 5.3E-14 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_27485 8c984f0006b2ba58357dbe154e50c411 128 PRINTS PR00604 Class IA and IB cytochrome C signature 36 43 5.3E-14 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_27485 8c984f0006b2ba58357dbe154e50c411 128 PRINTS PR00604 Class IA and IB cytochrome C signature 65 75 5.3E-14 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_27485 8c984f0006b2ba58357dbe154e50c411 128 PRINTS PR00604 Class IA and IB cytochrome C signature 79 95 5.3E-14 T 14-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_27485 8c984f0006b2ba58357dbe154e50c411 128 Pfam PF00034 Cytochrome c 28 124 6.7E-8 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_27485 8c984f0006b2ba58357dbe154e50c411 128 Gene3D G3DSA:1.10.760.10 14 124 1.8E-32 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_27485 8c984f0006b2ba58357dbe154e50c411 128 SUPERFAMILY SSF46626 24 124 2.3E-29 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_29210 ef1c51e652d6a2dbef9049baa32b25e1 92 Gene3D G3DSA:1.10.1200.10 1 79 3.2E-6 T 14-10-2018 IPR036736 ACP-like superfamily TSH58p_29210 ef1c51e652d6a2dbef9049baa32b25e1 92 SUPERFAMILY SSF47336 5 77 3.14E-7 T 14-10-2018 IPR036736 ACP-like superfamily TSH58p_29210 ef1c51e652d6a2dbef9049baa32b25e1 92 Pfam PF00550 Phosphopantetheine attachment site 18 77 2.9E-5 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain TSH58p_23695 407de278734c42a2f0ce4eaf2e6e0c87 157 SUPERFAMILY SSF46785 6 122 2.26E-31 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_23695 407de278734c42a2f0ce4eaf2e6e0c87 157 SMART SM00347 32 130 2.6E-20 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_23695 407de278734c42a2f0ce4eaf2e6e0c87 157 Pfam PF01047 MarR family 39 97 2.8E-16 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_23695 407de278734c42a2f0ce4eaf2e6e0c87 157 Gene3D G3DSA:1.10.10.10 4 144 1.0E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_20065 8c1e67f58538e81fb9d24dd3e5944261 96 Pfam PF11747 Killing trait 11 78 1.1E-30 T 14-10-2018 IPR021070 Killing trait, RebB TSH58p_05515 9d9ad307c73d4aeab28d70bda97a3c4e 244 SUPERFAMILY SSF144091 2 205 1.44E-39 T 14-10-2018 TSH58p_05515 9d9ad307c73d4aeab28d70bda97a3c4e 244 Pfam PF01694 Rhomboid family 52 204 4.5E-40 T 14-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 TSH58p_05515 9d9ad307c73d4aeab28d70bda97a3c4e 244 Gene3D G3DSA:1.20.1540.10 1 210 3.5E-30 T 14-10-2018 IPR035952 Rhomboid-like superfamily TSH58p_25380 323f69a5bb220e44f1b6173657d84f56 346 SMART SM00829 8 343 0.0045 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TSH58p_25380 323f69a5bb220e44f1b6173657d84f56 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 139 2.5E-32 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TSH58p_25380 323f69a5bb220e44f1b6173657d84f56 346 SUPERFAMILY SSF50129 1 177 5.93E-54 T 14-10-2018 IPR011032 GroES-like superfamily TSH58p_25380 323f69a5bb220e44f1b6173657d84f56 346 Gene3D G3DSA:3.90.180.10 8 332 3.0E-102 T 14-10-2018 TSH58p_25380 323f69a5bb220e44f1b6173657d84f56 346 SUPERFAMILY SSF51735 149 302 4.6E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_25380 323f69a5bb220e44f1b6173657d84f56 346 Pfam PF00107 Zinc-binding dehydrogenase 179 305 7.6E-19 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TSH58p_25380 323f69a5bb220e44f1b6173657d84f56 346 Gene3D G3DSA:3.40.50.720 156 292 3.0E-102 T 14-10-2018 TSH58p_25380 323f69a5bb220e44f1b6173657d84f56 346 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 TSH58p_29165 984b0c4ba9442bb1d0806b119ecb7eaa 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 253 8.6E-49 T 14-10-2018 TSH58p_29165 984b0c4ba9442bb1d0806b119ecb7eaa 256 Gene3D G3DSA:3.40.50.720 1 255 3.9E-65 T 14-10-2018 TSH58p_29165 984b0c4ba9442bb1d0806b119ecb7eaa 256 SUPERFAMILY SSF51735 9 255 6.33E-65 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_29165 984b0c4ba9442bb1d0806b119ecb7eaa 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 14 182 0.0016 T 14-10-2018 TSH58p_29165 984b0c4ba9442bb1d0806b119ecb7eaa 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 6.8E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_29165 984b0c4ba9442bb1d0806b119ecb7eaa 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 6.8E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_29165 984b0c4ba9442bb1d0806b119ecb7eaa 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 6.8E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_29165 984b0c4ba9442bb1d0806b119ecb7eaa 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 6.8E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_29165 984b0c4ba9442bb1d0806b119ecb7eaa 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 6.8E-26 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_26820 efd6907a154ce6c02dc03d1a0e8c92f2 282 Pfam PF07859 alpha/beta hydrolase fold 69 180 1.4E-13 T 14-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 TSH58p_26820 efd6907a154ce6c02dc03d1a0e8c92f2 282 SUPERFAMILY SSF53474 9 271 4.61E-44 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_26820 efd6907a154ce6c02dc03d1a0e8c92f2 282 Gene3D G3DSA:3.40.50.1820 3 278 2.3E-57 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_16380 7f60436a30d3ce19954238f35377da24 434 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 419 1.4E-95 T 14-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 TSH58p_16380 7f60436a30d3ce19954238f35377da24 434 Gene3D G3DSA:3.65.10.10 21 238 5.9E-159 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 TSH58p_16380 7f60436a30d3ce19954238f35377da24 434 SUPERFAMILY SSF55205 1 430 3.76E-133 T 14-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 TSH58p_16380 7f60436a30d3ce19954238f35377da24 434 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 428 3.9E-167 T 14-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSH58p_16380 7f60436a30d3ce19954238f35377da24 434 Gene3D G3DSA:3.65.10.10 6 426 5.9E-159 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 TSH58p_16380 7f60436a30d3ce19954238f35377da24 434 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 429 44.336 T 14-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSH58p_19695 8b5a0b8261cb1b885ba46a8acb270b8a 475 Pfam PF00171 Aldehyde dehydrogenase family 11 278 7.6E-24 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TSH58p_19695 8b5a0b8261cb1b885ba46a8acb270b8a 475 SUPERFAMILY SSF53720 15 454 4.32E-75 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSH58p_19695 8b5a0b8261cb1b885ba46a8acb270b8a 475 Gene3D G3DSA:3.40.605.10 21 451 2.2E-159 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TSH58p_19695 8b5a0b8261cb1b885ba46a8acb270b8a 475 Gene3D G3DSA:3.40.309.10 228 412 2.2E-159 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TSH58p_14690 bb9453c50de365b702f0fa9fb7440716 336 SUPERFAMILY SSF52540 49 201 2.05E-9 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_14690 bb9453c50de365b702f0fa9fb7440716 336 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 20 321 2.6E-89 T 14-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 TSH58p_14690 bb9453c50de365b702f0fa9fb7440716 336 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 2 330 33.983 T 14-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 TSH58p_14690 bb9453c50de365b702f0fa9fb7440716 336 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 19 313 8.2E-55 T 14-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 TSH58p_25875 989b5fc90143b73778e980866a7f5cc0 274 Gene3D G3DSA:3.40.50.300 38 274 2.8E-66 T 14-10-2018 TSH58p_25875 989b5fc90143b73778e980866a7f5cc0 274 SMART SM00382 62 249 9.7E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_25875 989b5fc90143b73778e980866a7f5cc0 274 SUPERFAMILY SSF52540 42 269 2.66E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_25875 989b5fc90143b73778e980866a7f5cc0 274 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 38 274 5.1E-113 T 14-10-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 TSH58p_25875 989b5fc90143b73778e980866a7f5cc0 274 Pfam PF00005 ABC transporter 54 198 2.8E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_25875 989b5fc90143b73778e980866a7f5cc0 274 ProSitePatterns PS00211 ABC transporters family signature. 171 185 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_25875 989b5fc90143b73778e980866a7f5cc0 274 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 248 269 3.7E-6 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSH58p_05825 d5176d2b28cab70281960b47da52447b 82 Pfam PF07330 Protein of unknown function (DUF1467) 1 78 9.3E-27 T 14-10-2018 IPR009935 Protein of unknown function DUF1467 TSH58p_31965 f7f799e3c50cea249dd0a0bb439e854a 407 Pfam PF13609 Gram-negative porin 10 377 2.2E-47 T 14-10-2018 TSH58p_31965 f7f799e3c50cea249dd0a0bb439e854a 407 SUPERFAMILY SSF56935 22 398 1.74E-24 T 14-10-2018 TSH58p_24350 03e56692a3348788061f47e77d8dc669 437 SUPERFAMILY SSF54631 202 337 2.27E-30 T 14-10-2018 TSH58p_24350 03e56692a3348788061f47e77d8dc669 437 Gene3D G3DSA:3.10.580.10 196 347 4.4E-44 T 14-10-2018 TSH58p_24350 03e56692a3348788061f47e77d8dc669 437 Pfam PF00571 CBS domain 286 334 1.5E-6 T 14-10-2018 IPR000644 CBS domain TSH58p_24350 03e56692a3348788061f47e77d8dc669 437 Pfam PF00571 CBS domain 216 270 0.0061 T 14-10-2018 IPR000644 CBS domain TSH58p_24350 03e56692a3348788061f47e77d8dc669 437 SUPERFAMILY SSF56176 348 429 1.04E-23 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TSH58p_24350 03e56692a3348788061f47e77d8dc669 437 SMART SM00116 286 334 0.0028 T 14-10-2018 IPR000644 CBS domain TSH58p_24350 03e56692a3348788061f47e77d8dc669 437 SMART SM00116 224 273 16.0 T 14-10-2018 IPR000644 CBS domain TSH58p_24350 03e56692a3348788061f47e77d8dc669 437 Pfam PF03471 Transporter associated domain 350 427 2.9E-23 T 14-10-2018 IPR005170 Transporter-associated domain TSH58p_24350 03e56692a3348788061f47e77d8dc669 437 Gene3D G3DSA:3.30.465.10 348 430 1.6E-34 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TSH58p_24350 03e56692a3348788061f47e77d8dc669 437 SMART SM01091 349 429 4.8E-31 T 14-10-2018 IPR005170 Transporter-associated domain TSH58p_24350 03e56692a3348788061f47e77d8dc669 437 Pfam PF01595 Domain of unknown function DUF21 6 200 6.9E-49 T 14-10-2018 IPR002550 CNNM, transmembrane domain TSH58p_18860 665c38062f4037a9f7e18212fa00547d 345 Pfam PF04230 Polysaccharide pyruvyl transferase 71 322 7.6E-20 T 14-10-2018 IPR007345 Polysaccharide pyruvyl transferase TSH58p_30195 9469e3acfb44d7ac0d6e1aaab6b96748 373 Gene3D G3DSA:2.40.30.10 99 238 2.3E-35 T 14-10-2018 TSH58p_30195 9469e3acfb44d7ac0d6e1aaab6b96748 373 Pfam PF08021 Siderophore-interacting FAD-binding domain 115 237 2.5E-26 T 14-10-2018 IPR013113 FAD-binding 9, siderophore-interacting TSH58p_30195 9469e3acfb44d7ac0d6e1aaab6b96748 373 SUPERFAMILY SSF63380 109 237 5.86E-9 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TSH58p_30195 9469e3acfb44d7ac0d6e1aaab6b96748 373 Gene3D G3DSA:3.40.50.80 240 367 1.5E-43 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TSH58p_30195 9469e3acfb44d7ac0d6e1aaab6b96748 373 Pfam PF04954 Siderophore-interacting protein 243 360 1.3E-37 T 14-10-2018 IPR007037 Siderophore-interacting protein, C-terminal domain TSH58p_32645 9469e3acfb44d7ac0d6e1aaab6b96748 373 Gene3D G3DSA:2.40.30.10 99 238 2.3E-35 T 14-10-2018 TSH58p_32645 9469e3acfb44d7ac0d6e1aaab6b96748 373 Pfam PF08021 Siderophore-interacting FAD-binding domain 115 237 2.5E-26 T 14-10-2018 IPR013113 FAD-binding 9, siderophore-interacting TSH58p_32645 9469e3acfb44d7ac0d6e1aaab6b96748 373 SUPERFAMILY SSF63380 109 237 5.86E-9 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TSH58p_32645 9469e3acfb44d7ac0d6e1aaab6b96748 373 Gene3D G3DSA:3.40.50.80 240 367 1.5E-43 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TSH58p_32645 9469e3acfb44d7ac0d6e1aaab6b96748 373 Pfam PF04954 Siderophore-interacting protein 243 360 1.3E-37 T 14-10-2018 IPR007037 Siderophore-interacting protein, C-terminal domain TSH58p_17295 3e91ade1994ffd99503d598ebc210377 155 Pfam PF04355 SmpA / OmlA family 30 104 8.0E-17 T 14-10-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 TSH58p_17295 3e91ade1994ffd99503d598ebc210377 155 Gene3D G3DSA:3.30.1450.10 29 118 5.7E-11 T 14-10-2018 IPR037873 BamE-like TSH58p_31700 6f23664d823f1c349ae919d0956a26f8 438 Pfam PF00202 Aminotransferase class-III 42 434 3.0E-74 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSH58p_31700 6f23664d823f1c349ae919d0956a26f8 438 PIRSF PIRSF000521 185 438 5.3E-31 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSH58p_31700 6f23664d823f1c349ae919d0956a26f8 438 PIRSF PIRSF000521 40 158 9.0E-7 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSH58p_31700 6f23664d823f1c349ae919d0956a26f8 438 Gene3D G3DSA:3.90.1150.10 41 431 4.3E-134 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_31700 6f23664d823f1c349ae919d0956a26f8 438 SUPERFAMILY SSF53383 33 436 5.16E-104 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_31700 6f23664d823f1c349ae919d0956a26f8 438 Gene3D G3DSA:3.40.640.10 74 333 4.3E-134 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_31700 6f23664d823f1c349ae919d0956a26f8 438 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 248 286 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSH58p_01475 4c915b26be071e241b8be7ee01b11072 296 Pfam PF00950 ABC 3 transport family 26 286 3.2E-49 T 14-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 TSH58p_01475 4c915b26be071e241b8be7ee01b11072 296 SUPERFAMILY SSF81345 23 283 1.57E-30 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_01475 4c915b26be071e241b8be7ee01b11072 296 Gene3D G3DSA:1.10.3470.10 58 290 2.9E-7 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_30950 de24b856e42df2cd211c70c84955e3b0 360 SUPERFAMILY SSF52922 223 360 2.22E-30 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSH58p_30950 de24b856e42df2cd211c70c84955e3b0 360 SUPERFAMILY SSF52518 35 217 1.02E-48 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_30950 de24b856e42df2cd211c70c84955e3b0 360 SMART SM00861 53 217 6.9E-41 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSH58p_30950 de24b856e42df2cd211c70c84955e3b0 360 Pfam PF02779 Transketolase, pyrimidine binding domain 59 216 1.9E-33 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSH58p_30950 de24b856e42df2cd211c70c84955e3b0 360 Gene3D G3DSA:3.40.50.970 53 223 5.3E-49 T 14-10-2018 TSH58p_30950 de24b856e42df2cd211c70c84955e3b0 360 Pfam PF02780 Transketolase, C-terminal domain 229 351 9.9E-26 T 14-10-2018 IPR033248 Transketolase, C-terminal domain TSH58p_30950 de24b856e42df2cd211c70c84955e3b0 360 Gene3D G3DSA:3.40.50.920 229 360 3.9E-31 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSH58p_24275 51b64d0c401ce533228ef588db9bed76 274 Pfam PF12146 Serine aminopeptidase, S33 74 175 1.1E-12 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 TSH58p_24275 51b64d0c401ce533228ef588db9bed76 274 Gene3D G3DSA:3.40.50.1820 48 265 6.6E-38 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_24275 51b64d0c401ce533228ef588db9bed76 274 SUPERFAMILY SSF53474 37 249 3.85E-40 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_10235 0fd701826f4ee18eda1604a45b04b2b5 156 Pfam PF04214 Protein of unknown function, DUF 63 131 1.3E-33 T 14-10-2018 IPR007332 Protein of unknown function DUF411 TSH58p_06340 7f5686520c5133e5e9bd13157c3d14b3 133 Pfam PF00565 Staphylococcal nuclease homologue 13 114 2.1E-11 T 14-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 TSH58p_06340 7f5686520c5133e5e9bd13157c3d14b3 133 SMART SM00318 2 115 9.9E-5 T 14-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 TSH58p_06340 7f5686520c5133e5e9bd13157c3d14b3 133 Gene3D G3DSA:2.40.50.90 1 127 5.2E-19 T 14-10-2018 IPR035437 SNase-like, OB-fold superfamily TSH58p_06340 7f5686520c5133e5e9bd13157c3d14b3 133 SUPERFAMILY SSF50199 2 117 1.44E-23 T 14-10-2018 TSH58p_07780 867d2f48b32fb8a7a3e95816ba7d9fed 202 SUPERFAMILY SSF50249 137 200 4.05E-21 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_07780 867d2f48b32fb8a7a3e95816ba7d9fed 202 Gene3D G3DSA:2.40.50.140 134 200 2.2E-23 T 14-10-2018 TSH58p_07780 867d2f48b32fb8a7a3e95816ba7d9fed 202 Gene3D G3DSA:2.40.50.140 18 85 7.6E-20 T 14-10-2018 TSH58p_07780 867d2f48b32fb8a7a3e95816ba7d9fed 202 Pfam PF00313 'Cold-shock' DNA-binding domain 21 83 9.7E-17 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_07780 867d2f48b32fb8a7a3e95816ba7d9fed 202 Pfam PF00313 'Cold-shock' DNA-binding domain 138 199 1.0E-23 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_07780 867d2f48b32fb8a7a3e95816ba7d9fed 202 PRINTS PR00050 Cold shock protein signature 139 154 3.7E-13 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_07780 867d2f48b32fb8a7a3e95816ba7d9fed 202 PRINTS PR00050 Cold shock protein signature 160 169 3.7E-13 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_07780 867d2f48b32fb8a7a3e95816ba7d9fed 202 PRINTS PR00050 Cold shock protein signature 175 193 3.7E-13 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_07780 867d2f48b32fb8a7a3e95816ba7d9fed 202 SMART SM00357 138 202 1.3E-19 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 TSH58p_07780 867d2f48b32fb8a7a3e95816ba7d9fed 202 SMART SM00357 21 85 9.0E-16 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 TSH58p_07780 867d2f48b32fb8a7a3e95816ba7d9fed 202 SUPERFAMILY SSF50249 20 84 1.56E-17 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_12095 9ab76717b8c16d257e2ca34fee5224d1 353 SUPERFAMILY SSF103481 203 295 6.15E-11 T 14-10-2018 TSH58p_12095 9ab76717b8c16d257e2ca34fee5224d1 353 Pfam PF00892 EamA-like transporter family 4 144 7.5E-21 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_12095 9ab76717b8c16d257e2ca34fee5224d1 353 Pfam PF00892 EamA-like transporter family 160 290 3.3E-10 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_12095 9ab76717b8c16d257e2ca34fee5224d1 353 SUPERFAMILY SSF103481 68 148 4.71E-14 T 14-10-2018 TSH58p_01690 885b64e945cb39c863bbcbb2bec3baeb 117 Pfam PF12728 Helix-turn-helix domain 66 114 2.9E-9 T 14-10-2018 TSH58p_01690 885b64e945cb39c863bbcbb2bec3baeb 117 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 67 113 6.4E-9 T 14-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 TSH58p_01690 885b64e945cb39c863bbcbb2bec3baeb 117 Gene3D G3DSA:1.10.1660.10 63 114 9.8E-10 T 14-10-2018 TSH58p_25320 7cc6a5f4f4bf308f4b761f06288522a4 676 Gene3D G3DSA:3.40.50.300 1 181 7.9E-42 T 14-10-2018 TSH58p_25320 7cc6a5f4f4bf308f4b761f06288522a4 676 Pfam PF00271 Helicase conserved C-terminal domain 212 310 1.2E-17 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_25320 7cc6a5f4f4bf308f4b761f06288522a4 676 SUPERFAMILY SSF52540 5 321 4.23E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_25320 7cc6a5f4f4bf308f4b761f06288522a4 676 SMART SM00490 231 312 5.2E-22 T 14-10-2018 IPR001650 Helicase, C-terminal TSH58p_25320 7cc6a5f4f4bf308f4b761f06288522a4 676 SMART SM00487 1 197 9.0E-21 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSH58p_25320 7cc6a5f4f4bf308f4b761f06288522a4 676 Gene3D G3DSA:3.40.50.300 189 361 4.2E-29 T 14-10-2018 TSH58p_25320 7cc6a5f4f4bf308f4b761f06288522a4 676 Pfam PF00270 DEAD/DEAH box helicase 3 165 7.5E-23 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TSH58p_29810 eb2e089efd28cfb7d08b1f096a6b77d3 111 PIRSF PIRSF025560 1 111 1.0E-24 T 14-10-2018 IPR008309 Uncharacterised conserved protein UCP025560 TSH58p_29810 eb2e089efd28cfb7d08b1f096a6b77d3 111 Pfam PF07027 Protein of unknown function (DUF1318) 24 111 5.5E-25 T 14-10-2018 IPR008309 Uncharacterised conserved protein UCP025560 TSH58p_11135 46fb61348ada270ae07002346629f948 249 Pfam PF00977 Histidine biosynthesis protein 3 230 2.7E-79 T 14-10-2018 IPR006062 Histidine biosynthesis GO:0000105 TSH58p_11135 46fb61348ada270ae07002346629f948 249 Gene3D G3DSA:3.20.20.70 1 240 1.1E-84 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_11135 46fb61348ada270ae07002346629f948 249 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 234 6.0E-84 T 14-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 TSH58p_11135 46fb61348ada270ae07002346629f948 249 SUPERFAMILY SSF51366 1 238 5.65E-73 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TSH58p_11135 46fb61348ada270ae07002346629f948 249 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 238 36.072 T 14-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 TSH58p_12410 5600ca1b0eea3131cf02976d8584f912 214 PIRSF PIRSF029287 2 207 5.2E-44 T 14-10-2018 IPR017748 T6S-associated protein TagF TSH58p_12410 5600ca1b0eea3131cf02976d8584f912 214 Pfam PF09867 Uncharacterized protein conserved in bacteria (DUF2094) 8 140 1.0E-42 T 14-10-2018 IPR017748 T6S-associated protein TagF TSH58p_12410 5600ca1b0eea3131cf02976d8584f912 214 TIGRFAM TIGR03373 VI_minor_4: type VI secretion-associated protein, BMA_A0400 family 8 140 4.3E-39 T 14-10-2018 IPR017748 T6S-associated protein TagF TSH58p_12410 5600ca1b0eea3131cf02976d8584f912 214 Gene3D G3DSA:3.40.1730.10 5 210 5.7E-55 T 14-10-2018 IPR038225 T6S-associated protein TagF superfamily TSH58p_11610 a99b8bfda64c3ee3875a1d2f6153a70f 402 SUPERFAMILY SSF88697 13 81 5.22E-11 T 14-10-2018 IPR015947 PUA-like superfamily TSH58p_11610 a99b8bfda64c3ee3875a1d2f6153a70f 402 SUPERFAMILY SSF53335 91 398 3.38E-67 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_11610 a99b8bfda64c3ee3875a1d2f6153a70f 402 Gene3D G3DSA:2.30.130.10 13 81 1.9E-19 T 14-10-2018 IPR036974 PUA domain superfamily GO:0003723 TSH58p_11610 a99b8bfda64c3ee3875a1d2f6153a70f 402 Gene3D G3DSA:3.40.50.150 189 402 3.9E-65 T 14-10-2018 TSH58p_11610 a99b8bfda64c3ee3875a1d2f6153a70f 402 Gene3D G3DSA:3.30.750.80 84 188 1.2E-32 T 14-10-2018 TSH58p_11610 a99b8bfda64c3ee3875a1d2f6153a70f 402 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 179 361 2.4E-18 T 14-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 TSH58p_19275 709151d15ec27fd611ac51243f8b1ca8 250 SUPERFAMILY SSF48008 100 228 4.97E-27 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_19275 709151d15ec27fd611ac51243f8b1ca8 250 SMART SM00345 35 93 8.9E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_19275 709151d15ec27fd611ac51243f8b1ca8 250 Gene3D G3DSA:1.20.120.530 99 229 1.8E-28 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_19275 709151d15ec27fd611ac51243f8b1ca8 250 SUPERFAMILY SSF46785 27 97 3.15E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_19275 709151d15ec27fd611ac51243f8b1ca8 250 SMART SM00895 103 227 1.3E-18 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_19275 709151d15ec27fd611ac51243f8b1ca8 250 Pfam PF07729 FCD domain 107 226 4.7E-29 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_19275 709151d15ec27fd611ac51243f8b1ca8 250 Pfam PF00392 Bacterial regulatory proteins, gntR family 33 93 1.4E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_19275 709151d15ec27fd611ac51243f8b1ca8 250 Gene3D G3DSA:1.10.10.10 28 94 1.5E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_31935 5216355b361429d08692b1d1664e14f8 462 SUPERFAMILY SSF75304 37 448 1.11E-81 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_31935 5216355b361429d08692b1d1664e14f8 462 ProSitePatterns PS00571 Amidases signature. 148 179 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 TSH58p_31935 5216355b361429d08692b1d1664e14f8 462 Gene3D G3DSA:3.90.1300.10 24 441 3.7E-82 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_31935 5216355b361429d08692b1d1664e14f8 462 Pfam PF01425 Amidase 61 430 7.3E-54 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_09125 0dc3b7da3bcedf3bd8bd19a6229423ea 351 SUPERFAMILY SSF53850 41 264 2.88E-35 T 14-10-2018 TSH58p_09125 0dc3b7da3bcedf3bd8bd19a6229423ea 351 Pfam PF09084 NMT1/THI5 like 79 246 2.2E-15 T 14-10-2018 IPR015168 SsuA/THI5-like TSH58p_09125 0dc3b7da3bcedf3bd8bd19a6229423ea 351 Gene3D G3DSA:3.40.190.10 29 339 2.0E-108 T 14-10-2018 TSH58p_09125 0dc3b7da3bcedf3bd8bd19a6229423ea 351 Gene3D G3DSA:3.40.190.10 116 218 2.0E-108 T 14-10-2018 TSH58p_27025 dea65c25cfbdf68c82b29fbee065b244 274 SUPERFAMILY SSF53474 3 272 1.06E-65 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_27025 dea65c25cfbdf68c82b29fbee065b244 274 Gene3D G3DSA:3.40.50.1820 2 273 5.0E-83 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_27025 dea65c25cfbdf68c82b29fbee065b244 274 Pfam PF00561 alpha/beta hydrolase fold 22 253 1.2E-22 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_27025 dea65c25cfbdf68c82b29fbee065b244 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 1.7E-11 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_27025 dea65c25cfbdf68c82b29fbee065b244 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 1.7E-11 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_27025 dea65c25cfbdf68c82b29fbee065b244 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 216 230 1.7E-11 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_27025 dea65c25cfbdf68c82b29fbee065b244 274 PRINTS PR00412 Epoxide hydrolase signature 27 45 8.6E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TSH58p_27025 dea65c25cfbdf68c82b29fbee065b244 274 PRINTS PR00412 Epoxide hydrolase signature 214 230 8.6E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TSH58p_27025 dea65c25cfbdf68c82b29fbee065b244 274 PRINTS PR00412 Epoxide hydrolase signature 47 62 8.6E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TSH58p_13310 7030ae4b22c54f212a9216f347c6338a 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.2E-24 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_13310 7030ae4b22c54f212a9216f347c6338a 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.5E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_13310 7030ae4b22c54f212a9216f347c6338a 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.5E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_13310 7030ae4b22c54f212a9216f347c6338a 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.5E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_13310 7030ae4b22c54f212a9216f347c6338a 296 Pfam PF03466 LysR substrate binding domain 87 290 7.0E-38 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_13310 7030ae4b22c54f212a9216f347c6338a 296 SUPERFAMILY SSF53850 88 293 7.06E-42 T 14-10-2018 TSH58p_13310 7030ae4b22c54f212a9216f347c6338a 296 Gene3D G3DSA:3.40.190.290 90 291 4.1E-50 T 14-10-2018 TSH58p_13310 7030ae4b22c54f212a9216f347c6338a 296 SUPERFAMILY SSF46785 1 111 3.98E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_13310 7030ae4b22c54f212a9216f347c6338a 296 Gene3D G3DSA:1.10.10.10 1 85 2.5E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_05240 f9c89e553798d439b1fec74646a1a084 363 PIRSF PIRSF000112 1 359 5.8E-96 T 14-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 TSH58p_05240 f9c89e553798d439b1fec74646a1a084 363 SUPERFAMILY SSF56796 4 355 1.57E-86 T 14-10-2018 TSH58p_05240 f9c89e553798d439b1fec74646a1a084 363 Gene3D G3DSA:1.20.1090.10 159 363 4.7E-78 T 14-10-2018 TSH58p_05240 f9c89e553798d439b1fec74646a1a084 363 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 149 177 - T 14-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 TSH58p_05240 f9c89e553798d439b1fec74646a1a084 363 Gene3D G3DSA:3.40.50.1970 4 158 4.2E-43 T 14-10-2018 TSH58p_05240 f9c89e553798d439b1fec74646a1a084 363 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 240 260 - T 14-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 TSH58p_05240 f9c89e553798d439b1fec74646a1a084 363 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 346 9.3E-65 T 14-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 TSH58p_04135 077af695f19ffd3252460fa7d14e5d7c 404 Gene3D G3DSA:3.40.50.2300 150 282 4.0E-114 T 14-10-2018 TSH58p_04135 077af695f19ffd3252460fa7d14e5d7c 404 SUPERFAMILY SSF53822 31 402 9.76E-93 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_04135 077af695f19ffd3252460fa7d14e5d7c 404 Gene3D G3DSA:3.40.50.2300 34 343 4.0E-114 T 14-10-2018 TSH58p_04135 077af695f19ffd3252460fa7d14e5d7c 404 Pfam PF13458 Periplasmic binding protein 31 368 1.3E-91 T 14-10-2018 IPR028081 Leucine-binding protein domain TSH58p_16570 b66c1cb3f3d6eaf1efbfa33c0ce9d421 370 Pfam PF00561 alpha/beta hydrolase fold 106 344 2.4E-23 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_16570 b66c1cb3f3d6eaf1efbfa33c0ce9d421 370 PRINTS PR00111 Alpha/beta hydrolase fold signature 132 147 1.6E-11 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_16570 b66c1cb3f3d6eaf1efbfa33c0ce9d421 370 PRINTS PR00111 Alpha/beta hydrolase fold signature 177 190 1.6E-11 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_16570 b66c1cb3f3d6eaf1efbfa33c0ce9d421 370 PRINTS PR00111 Alpha/beta hydrolase fold signature 191 204 1.6E-11 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_16570 b66c1cb3f3d6eaf1efbfa33c0ce9d421 370 PRINTS PR00111 Alpha/beta hydrolase fold signature 303 317 1.6E-11 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_16570 b66c1cb3f3d6eaf1efbfa33c0ce9d421 370 SUPERFAMILY SSF53474 79 356 5.13E-55 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_16570 b66c1cb3f3d6eaf1efbfa33c0ce9d421 370 Gene3D G3DSA:3.40.50.1820 65 357 1.7E-56 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_00140 cc7c7654c6a8cfe1e473160ca07c4a5f 118 Pfam PF09585 Conserved hypothetical protein (Lin0512_fam) 5 116 2.9E-42 T 14-10-2018 IPR011719 Conserved hypothetical protein CHP02058 TSH58p_00140 cc7c7654c6a8cfe1e473160ca07c4a5f 118 TIGRFAM TIGR02058 lin0512_fam: conserved hypothetical protein 3 118 2.6E-46 T 14-10-2018 IPR011719 Conserved hypothetical protein CHP02058 TSH58p_00140 cc7c7654c6a8cfe1e473160ca07c4a5f 118 Gene3D G3DSA:3.30.1330.20 1 118 2.1E-41 T 14-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 TSH58p_01555 1cad44b39d492a7ee390f05a8b6aa955 427 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 7 416 5.2E-119 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TSH58p_01555 1cad44b39d492a7ee390f05a8b6aa955 427 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 419 7.0E-144 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSH58p_01555 1cad44b39d492a7ee390f05a8b6aa955 427 PIRSF PIRSF006066 1 426 1.7E-140 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSH58p_02670 f9453dd29ece2790ac9d085e44927b2b 182 SUPERFAMILY SSF88659 94 153 3.92E-14 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSH58p_02670 f9453dd29ece2790ac9d085e44927b2b 182 Gene3D G3DSA:1.10.10.10 97 155 4.8E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_02670 f9453dd29ece2790ac9d085e44927b2b 182 Pfam PF04542 Sigma-70 region 2 7 70 1.0E-15 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_02670 f9453dd29ece2790ac9d085e44927b2b 182 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 153 3.5E-20 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TSH58p_02670 f9453dd29ece2790ac9d085e44927b2b 182 Gene3D G3DSA:1.10.1740.10 1 74 3.0E-20 T 14-10-2018 TSH58p_02670 f9453dd29ece2790ac9d085e44927b2b 182 Pfam PF08281 Sigma-70, region 4 101 150 1.1E-13 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSH58p_02670 f9453dd29ece2790ac9d085e44927b2b 182 SUPERFAMILY SSF88946 7 77 1.12E-18 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_14695 a881018b484c9e603a73d562b709d2f7 427 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 35 209 1.9E-59 T 14-10-2018 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 TSH58p_14695 a881018b484c9e603a73d562b709d2f7 427 SUPERFAMILY SSF53756 54 400 8.63E-11 T 14-10-2018 TSH58p_14695 a881018b484c9e603a73d562b709d2f7 427 Gene3D G3DSA:3.40.50.11720 33 208 5.1E-47 T 14-10-2018 IPR038107 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal domain superfamily KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 TSH58p_14695 a881018b484c9e603a73d562b709d2f7 427 Gene3D G3DSA:3.40.50.2000 217 401 4.8E-59 T 14-10-2018 TSH58p_18420 7a570177931fa194afa952e5d79ac3d9 285 Pfam PF01061 ABC-2 type transporter 44 246 2.4E-20 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TSH58p_28490 ae21fb61b684f82f3bd7814388f9bca2 393 Pfam PF13384 Homeodomain-like domain 35 70 1.2E-5 T 14-10-2018 TSH58p_01380 fa25f1f8161143f2a92de2fdabecb986 240 Gene3D G3DSA:3.40.50.300 3 240 1.9E-55 T 14-10-2018 TSH58p_01380 fa25f1f8161143f2a92de2fdabecb986 240 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_01380 fa25f1f8161143f2a92de2fdabecb986 240 Pfam PF00005 ABC transporter 23 167 1.5E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_01380 fa25f1f8161143f2a92de2fdabecb986 240 SMART SM00382 31 219 2.0E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_01380 fa25f1f8161143f2a92de2fdabecb986 240 SUPERFAMILY SSF52540 7 238 1.55E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_21910 7313fe22e5c1b1493c0fe8a5861b7d84 250 SUPERFAMILY SSF52540 2 235 2.93E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_21910 7313fe22e5c1b1493c0fe8a5861b7d84 250 Pfam PF00005 ABC transporter 17 172 6.4E-18 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_21910 7313fe22e5c1b1493c0fe8a5861b7d84 250 Gene3D G3DSA:3.40.50.300 1 246 3.0E-56 T 14-10-2018 TSH58p_21910 7313fe22e5c1b1493c0fe8a5861b7d84 250 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 3 243 3.1E-109 T 14-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 TSH58p_32015 81cf2d53dd336ffb513af458a99b0018 354 PRINTS PR00695 Copper containing nitrite reductase signature 146 161 9.3E-31 T 14-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 TSH58p_32015 81cf2d53dd336ffb513af458a99b0018 354 PRINTS PR00695 Copper containing nitrite reductase signature 121 140 9.3E-31 T 14-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 TSH58p_32015 81cf2d53dd336ffb513af458a99b0018 354 PRINTS PR00695 Copper containing nitrite reductase signature 163 179 9.3E-31 T 14-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 TSH58p_32015 81cf2d53dd336ffb513af458a99b0018 354 PRINTS PR00695 Copper containing nitrite reductase signature 60 78 9.3E-31 T 14-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 TSH58p_32015 81cf2d53dd336ffb513af458a99b0018 354 PRINTS PR00695 Copper containing nitrite reductase signature 86 102 9.3E-31 T 14-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 TSH58p_32015 81cf2d53dd336ffb513af458a99b0018 354 PRINTS PR00695 Copper containing nitrite reductase signature 104 121 9.3E-31 T 14-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 TSH58p_32015 81cf2d53dd336ffb513af458a99b0018 354 SUPERFAMILY SSF49503 181 339 1.63E-51 T 14-10-2018 IPR008972 Cupredoxin TSH58p_32015 81cf2d53dd336ffb513af458a99b0018 354 SUPERFAMILY SSF49503 56 197 2.84E-41 T 14-10-2018 IPR008972 Cupredoxin TSH58p_32015 81cf2d53dd336ffb513af458a99b0018 354 Gene3D G3DSA:2.60.40.420 27 180 7.0E-39 T 14-10-2018 IPR008972 Cupredoxin TSH58p_32015 81cf2d53dd336ffb513af458a99b0018 354 Gene3D G3DSA:2.60.40.420 181 345 1.2E-52 T 14-10-2018 IPR008972 Cupredoxin TSH58p_32015 81cf2d53dd336ffb513af458a99b0018 354 Pfam PF07732 Multicopper oxidase 69 181 7.3E-14 T 14-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 TSH58p_32015 81cf2d53dd336ffb513af458a99b0018 354 TIGRFAM TIGR02376 Cu_nitrite_red: nitrite reductase, copper-containing 38 340 2.1E-98 T 14-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 TSH58p_07910 a7c209ab3d0478ef19e0455899c7a481 120 PIRSF PIRSF032126 1 119 4.6E-25 T 14-10-2018 IPR016989 ATP synthase protein I, alphaproteobacterial TSH58p_07910 a7c209ab3d0478ef19e0455899c7a481 120 Pfam PF09527 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter 42 93 1.8E-18 T 14-10-2018 IPR032820 Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter TSH58p_13925 393ba16eb8d95055f13d8914ded502e4 195 SUPERFAMILY SSF52821 63 191 2.88E-14 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily TSH58p_13925 393ba16eb8d95055f13d8914ded502e4 195 Gene3D G3DSA:3.40.250.10 97 188 2.4E-10 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily TSH58p_13925 393ba16eb8d95055f13d8914ded502e4 195 TIGRFAM TIGR03865 PQQ_CXXCW: PQQ-dependent catabolism-associated CXXCW motif protein 33 189 1.9E-58 T 14-10-2018 IPR022376 PQQ-dependent catabolism-associated CXXCW motif TSH58p_29345 d93dce8a5b5db28e51826c480ee287d4 566 Gene3D G3DSA:3.40.1770.10 22 552 4.6E-255 T 14-10-2018 TSH58p_29345 d93dce8a5b5db28e51826c480ee287d4 566 Pfam PF17391 Urocanase N-terminal domain 17 143 2.0E-62 T 14-10-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 TSH58p_29345 d93dce8a5b5db28e51826c480ee287d4 566 Hamap MF_00577 Urocanate hydratase [hutU]. 2 566 50.656 T 14-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 TSH58p_29345 d93dce8a5b5db28e51826c480ee287d4 566 SUPERFAMILY SSF111326 13 565 6.93E-259 T 14-10-2018 IPR036190 Urocanase superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 TSH58p_29345 d93dce8a5b5db28e51826c480ee287d4 566 Gene3D G3DSA:3.40.50.10730 147 359 4.6E-255 T 14-10-2018 IPR038364 Urocanase, central domain superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 TSH58p_29345 d93dce8a5b5db28e51826c480ee287d4 566 PIRSF PIRSF001423 1 566 1.5E-293 T 14-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 TSH58p_29345 d93dce8a5b5db28e51826c480ee287d4 566 Pfam PF01175 Urocanase Rossmann-like domain 146 359 8.0E-84 T 14-10-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 TSH58p_29345 d93dce8a5b5db28e51826c480ee287d4 566 TIGRFAM TIGR01228 hutU: urocanate hydratase 16 564 7.4E-293 T 14-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 TSH58p_29345 d93dce8a5b5db28e51826c480ee287d4 566 Pfam PF17392 Urocanase C-terminal domain 362 556 1.3E-92 T 14-10-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 TSH58p_29345 d93dce8a5b5db28e51826c480ee287d4 566 ProSitePatterns PS01233 Urocanase signature. 452 467 - T 14-10-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 TSH58p_21245 2d6a9719964bbd85f382e66db3e855b4 263 SUPERFAMILY SSF53474 7 258 4.34E-20 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_31145 f04ac06b0ca27ca18dcabec6677d6cb8 319 Pfam PF00491 Arginase family 32 307 2.2E-55 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 TSH58p_31145 f04ac06b0ca27ca18dcabec6677d6cb8 319 Gene3D G3DSA:3.40.800.10 5 313 3.8E-72 T 14-10-2018 TSH58p_31145 f04ac06b0ca27ca18dcabec6677d6cb8 319 SUPERFAMILY SSF52768 8 311 9.36E-65 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily TSH58p_31280 58b6115c41d77f0decb963401bf6dba6 453 Gene3D G3DSA:3.20.140.10 14 382 9.6E-124 T 14-10-2018 TSH58p_31280 58b6115c41d77f0decb963401bf6dba6 453 SUPERFAMILY SSF54675 10 140 3.92E-39 T 14-10-2018 TSH58p_31280 58b6115c41d77f0decb963401bf6dba6 453 PIRSF PIRSF000484 8 447 3.6E-121 T 14-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 TSH58p_31280 58b6115c41d77f0decb963401bf6dba6 453 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 158 336 3.4E-12 T 14-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 TSH58p_31280 58b6115c41d77f0decb963401bf6dba6 453 SUPERFAMILY SSF51690 142 442 7.95E-98 T 14-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 TSH58p_31280 58b6115c41d77f0decb963401bf6dba6 453 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 14 434 1.5E-142 T 14-10-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 TSH58p_31280 58b6115c41d77f0decb963401bf6dba6 453 Gene3D G3DSA:3.20.20.70 154 322 9.6E-124 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_02895 22d06e37cd4f2f098f8140307cdbcc5e 598 SUPERFAMILY SSF48208 190 588 2.34E-110 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TSH58p_02895 22d06e37cd4f2f098f8140307cdbcc5e 598 Gene3D G3DSA:1.50.10.10 218 595 1.6E-88 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 TSH58p_02895 22d06e37cd4f2f098f8140307cdbcc5e 598 Pfam PF00723 Glycosyl hydrolases family 15 218 534 2.0E-62 T 14-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 TSH58p_08525 0f52e8aabe6bded18f0b5bfc4ed249bb 160 SUPERFAMILY SSF101116 10 126 1.26E-16 T 14-10-2018 IPR036584 Flagellar protein FliS superfamily GO:0044780 TSH58p_08525 0f52e8aabe6bded18f0b5bfc4ed249bb 160 Pfam PF02561 Flagellar protein FliS 11 124 7.3E-21 T 14-10-2018 IPR003713 Flagellar protein FliS GO:0044780 TSH58p_08525 0f52e8aabe6bded18f0b5bfc4ed249bb 160 Gene3D G3DSA:1.20.120.340 2 128 6.6E-17 T 14-10-2018 TSH58p_27070 15ef199deffadb8b9cbede46e114e5fc 139 SMART SM00054 109 137 0.096 T 14-10-2018 IPR002048 EF-hand domain GO:0005509 TSH58p_27070 15ef199deffadb8b9cbede46e114e5fc 139 SMART SM00054 39 67 15.0 T 14-10-2018 IPR002048 EF-hand domain GO:0005509 TSH58p_27070 15ef199deffadb8b9cbede46e114e5fc 139 SUPERFAMILY SSF47473 42 134 3.06E-10 T 14-10-2018 IPR011992 EF-hand domain pair TSH58p_27070 15ef199deffadb8b9cbede46e114e5fc 139 Pfam PF13202 EF hand 42 62 1.8E-5 T 14-10-2018 IPR002048 EF-hand domain GO:0005509 TSH58p_27070 15ef199deffadb8b9cbede46e114e5fc 139 ProSitePatterns PS00018 EF-hand calcium-binding domain. 48 60 - T 14-10-2018 IPR018247 EF-Hand 1, calcium-binding site TSH58p_03465 aa504f278a8d9ed6f6c25cbbf60c12b1 49 SUPERFAMILY SSF46955 7 40 2.01E-7 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily TSH58p_03465 aa504f278a8d9ed6f6c25cbbf60c12b1 49 Pfam PF00376 MerR family regulatory protein 8 41 6.7E-7 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_03465 aa504f278a8d9ed6f6c25cbbf60c12b1 49 Gene3D G3DSA:1.10.1660.10 1 42 1.5E-7 T 14-10-2018 TSH58p_14330 57fd208c26690272da519364805c8caa 374 Pfam PF01098 Cell cycle protein 27 368 2.6E-75 T 14-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_14330 57fd208c26690272da519364805c8caa 374 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 21 368 1.8E-102 T 14-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSH58p_04315 525ed0af33edb7595229464ae4627f40 372 SUPERFAMILY SSF161098 159 352 2.75E-41 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_04315 525ed0af33edb7595229464ae4627f40 372 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 181 367 5.0E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_04315 525ed0af33edb7595229464ae4627f40 372 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 160 258 1.4E-18 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 TSH58p_04315 525ed0af33edb7595229464ae4627f40 372 Gene3D G3DSA:1.10.3720.10 153 372 7.8E-47 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_17160 80525a6754d328ed7044f57aa495d96d 1439 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 1081 1439 1.2E-61 T 14-10-2018 IPR007452 Translocation and assembly module TamB TSH58p_02595 5104c0cc01b4a55773ece3116ac9ea54 232 Pfam PF02104 SURF1 family 11 212 4.7E-43 T 14-10-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_30295 af91bb254ce62bf7b3b704f4cb4d2f69 215 SUPERFAMILY SSF55718 45 156 1.55E-15 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily TSH58p_30295 af91bb254ce62bf7b3b704f4cb4d2f69 215 Pfam PF02036 SCP-2 sterol transfer family 95 150 2.6E-8 T 14-10-2018 IPR003033 SCP2 sterol-binding domain TSH58p_05325 3f3426f972868ade13061475ce14912a 212 SUPERFAMILY SSF110997 118 190 1.7E-8 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 TSH58p_05325 3f3426f972868ade13061475ce14912a 212 Pfam PF05036 Sporulation related domain 119 186 8.5E-5 T 14-10-2018 IPR007730 Sporulation-like domain GO:0042834 TSH58p_06300 c0a2ed97e3439e53bcdb884f157ff1ff 306 SUPERFAMILY SSF53448 12 275 3.09E-15 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_24210 2d90f772d6d3a3e8e278a4209b1b3824 468 SMART SM00028 106 139 81.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24210 2d90f772d6d3a3e8e278a4209b1b3824 468 SMART SM00028 38 71 140.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24210 2d90f772d6d3a3e8e278a4209b1b3824 468 SMART SM00028 4 37 320.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24210 2d90f772d6d3a3e8e278a4209b1b3824 468 SMART SM00028 140 173 0.21 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24210 2d90f772d6d3a3e8e278a4209b1b3824 468 SMART SM00028 72 105 6.5E-5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24210 2d90f772d6d3a3e8e278a4209b1b3824 468 SUPERFAMILY SSF53448 206 436 1.59E-22 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_24210 2d90f772d6d3a3e8e278a4209b1b3824 468 Pfam PF13181 Tetratricopeptide repeat 145 172 0.18 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_24210 2d90f772d6d3a3e8e278a4209b1b3824 468 Pfam PF14559 Tetratricopeptide repeat 88 137 2.8E-7 T 14-10-2018 TSH58p_24210 2d90f772d6d3a3e8e278a4209b1b3824 468 Pfam PF02709 N-terminal domain of galactosyltransferase 362 413 8.6E-10 T 14-10-2018 IPR027791 Galactosyltransferase, C-terminal Reactome: R-HSA-2022854|Reactome: R-HSA-975577 TSH58p_24210 2d90f772d6d3a3e8e278a4209b1b3824 468 Pfam PF13432 Tetratricopeptide repeat 9 56 0.0039 T 14-10-2018 TSH58p_24210 2d90f772d6d3a3e8e278a4209b1b3824 468 Gene3D G3DSA:3.90.550.10 199 456 3.7E-22 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_24210 2d90f772d6d3a3e8e278a4209b1b3824 468 SUPERFAMILY SSF48452 8 173 1.93E-30 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_24210 2d90f772d6d3a3e8e278a4209b1b3824 468 Gene3D G3DSA:1.25.40.10 3 179 2.2E-31 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_11690 4a693df96abb6a9b8c8c04a767ec4d1e 272 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_11690 4a693df96abb6a9b8c8c04a767ec4d1e 272 SMART SM00382 49 259 4.8E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_11690 4a693df96abb6a9b8c8c04a767ec4d1e 272 Gene3D G3DSA:3.40.50.300 25 270 7.7E-66 T 14-10-2018 TSH58p_11690 4a693df96abb6a9b8c8c04a767ec4d1e 272 Pfam PF00005 ABC transporter 40 196 8.0E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_11690 4a693df96abb6a9b8c8c04a767ec4d1e 272 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 25 272 1.3E-123 T 14-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 TSH58p_11690 4a693df96abb6a9b8c8c04a767ec4d1e 272 SUPERFAMILY SSF52540 26 259 9.55E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_07870 56e85e63b0c01f43b0af93435a6350b9 467 Pfam PF07593 ASPIC and UnbV 394 461 1.9E-19 T 14-10-2018 IPR011519 ASPIC/UnbV TSH58p_07870 56e85e63b0c01f43b0af93435a6350b9 467 SUPERFAMILY SSF69318 3 352 1.06E-31 T 14-10-2018 TSH58p_07870 56e85e63b0c01f43b0af93435a6350b9 467 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 24 85 1.4E-8 T 14-10-2018 TSH58p_00685 d3e8c06bbe99c5f34955689d65184fb9 155 SUPERFAMILY SSF52218 5 148 5.16E-25 T 14-10-2018 IPR029039 Flavoprotein-like superfamily TSH58p_00685 d3e8c06bbe99c5f34955689d65184fb9 155 Gene3D G3DSA:3.40.50.360 3 150 1.5E-17 T 14-10-2018 IPR029039 Flavoprotein-like superfamily TSH58p_21590 1cc8ad0d8bc1a0e255200bc547310446 220 ProDom PD037531 MEMBRANE HYDROGENASE SUBUNIT COMPONENT HYDROGENASE-4 E OXIDOREDUCTASE PRECURSOR SIGNAL 1.-.-.- 17 199 2.0E-44 T 14-10-2018 TSH58p_08980 9edc1517a13f8cfb211be5e139609ed4 303 Gene3D G3DSA:3.40.50.1820 54 301 4.7E-48 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_08980 9edc1517a13f8cfb211be5e139609ed4 303 SUPERFAMILY SSF53474 59 299 1.65E-33 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_08980 9edc1517a13f8cfb211be5e139609ed4 303 Pfam PF01738 Dienelactone hydrolase family 69 299 3.1E-17 T 14-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 TSH58p_25985 60496a320cebdd8f518109f3347e2efc 153 Gene3D G3DSA:2.30.30.40 53 110 3.9E-9 T 14-10-2018 TSH58p_25985 60496a320cebdd8f518109f3347e2efc 153 Pfam PF08239 Bacterial SH3 domain 59 107 2.2E-10 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type TSH58p_25985 60496a320cebdd8f518109f3347e2efc 153 SMART SM00287 48 112 3.2E-5 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type TSH58p_00330 e5cd0d22914da2c384d2a2be76dd23b4 275 Pfam PF08241 Methyltransferase domain 73 186 7.9E-17 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TSH58p_00330 e5cd0d22914da2c384d2a2be76dd23b4 275 Gene3D G3DSA:3.40.50.150 40 251 1.4E-26 T 14-10-2018 TSH58p_00330 e5cd0d22914da2c384d2a2be76dd23b4 275 SUPERFAMILY SSF53335 45 247 7.28E-25 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_28645 85516163abc01bf98e6287e4857d9ebd 143 Gene3D G3DSA:3.10.129.10 2 132 5.4E-37 T 14-10-2018 TSH58p_28645 85516163abc01bf98e6287e4857d9ebd 143 Pfam PF03061 Thioesterase superfamily 43 119 2.6E-12 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TSH58p_28645 85516163abc01bf98e6287e4857d9ebd 143 SUPERFAMILY SSF54637 10 129 1.82E-29 T 14-10-2018 IPR029069 HotDog domain superfamily TSH58p_28645 85516163abc01bf98e6287e4857d9ebd 143 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 15 124 8.8E-16 T 14-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 TSH58p_27725 079430158b1471d53bce719b7a3a7f82 141 SUPERFAMILY SSF55811 9 121 2.71E-18 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TSH58p_27725 079430158b1471d53bce719b7a3a7f82 141 Pfam PF00293 NUDIX domain 15 126 2.5E-10 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TSH58p_27725 079430158b1471d53bce719b7a3a7f82 141 Gene3D G3DSA:3.90.79.10 7 133 5.9E-25 T 14-10-2018 TSH58p_17605 4a20ee431f88d9624afba86771c27db1 683 Gene3D G3DSA:3.40.50.300 23 223 5.5E-10 T 14-10-2018 TSH58p_17605 4a20ee431f88d9624afba86771c27db1 683 Pfam PF05876 Phage terminase large subunit (GpA) 45 625 4.2E-94 T 14-10-2018 IPR008866 Bacteriophage lambda, GpA TSH58p_19855 0d75523b7115ddfe6403bc0157decb9c 215 Gene3D G3DSA:1.20.58.220 18 215 1.2E-48 T 14-10-2018 IPR038078 PhoU-like domain superfamily TSH58p_19855 0d75523b7115ddfe6403bc0157decb9c 215 Pfam PF01865 Protein of unknown function DUF47 12 212 4.3E-25 T 14-10-2018 IPR018445 Putative phosphate transport regulator TSH58p_28910 93f3892275fe4a5df868a662b8269583 85 Pfam PF06568 Domain of unknown function (DUF1127) 39 74 3.2E-14 T 14-10-2018 IPR009506 Protein of unknown function DUF1127 TSH58p_04980 d3a75dc23955a1a73ebaff581eb363dd 217 Gene3D G3DSA:1.10.4190.10 1 195 1.7E-55 T 14-10-2018 IPR038277 UreF domain superfamily TSH58p_04980 d3a75dc23955a1a73ebaff581eb363dd 217 Pfam PF01730 UreF 25 174 9.3E-35 T 14-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 TSH58p_04980 d3a75dc23955a1a73ebaff581eb363dd 217 PIRSF PIRSF009467 1 217 7.4E-58 T 14-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 TSH58p_04980 d3a75dc23955a1a73ebaff581eb363dd 217 Hamap MF_01385 Urease accessory protein UreF [ureF]. 1 217 27.804 T 14-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 TSH58p_25215 727472a0d5fc35c5256d0113b331c68d 58 Pfam PF01679 Proteolipid membrane potential modulator 2 50 1.1E-23 T 14-10-2018 IPR000612 Proteolipid membrane potential modulator GO:0016021 TSH58p_25215 727472a0d5fc35c5256d0113b331c68d 58 ProSitePatterns PS01309 Uncharacterized protein family UPF0057 signature. 7 22 - T 14-10-2018 IPR000612 Proteolipid membrane potential modulator GO:0016021 TSH58p_06540 9a3aed80ba95e023ab980e4c825e2779 298 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 85 255 5.2E-31 T 14-10-2018 TSH58p_06540 9a3aed80ba95e023ab980e4c825e2779 298 Gene3D G3DSA:3.40.50.1000 41 287 2.4E-66 T 14-10-2018 IPR023214 HAD superfamily TSH58p_06540 9a3aed80ba95e023ab980e4c825e2779 298 Pfam PF12710 haloacid dehalogenase-like hydrolase 87 253 1.6E-18 T 14-10-2018 TSH58p_06540 9a3aed80ba95e023ab980e4c825e2779 298 SUPERFAMILY SSF56784 82 291 6.27E-44 T 14-10-2018 IPR036412 HAD-like superfamily TSH58p_06540 9a3aed80ba95e023ab980e4c825e2779 298 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 76 285 1.9E-62 T 14-10-2018 TSH58p_02205 18d3cabdae23890ef7c6de733d882eb5 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 193 212 5.3E-16 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSH58p_02205 18d3cabdae23890ef7c6de733d882eb5 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 136 160 5.3E-16 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSH58p_02205 18d3cabdae23890ef7c6de733d882eb5 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 173 192 5.3E-16 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSH58p_02205 18d3cabdae23890ef7c6de733d882eb5 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 55 77 5.3E-16 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSH58p_02205 18d3cabdae23890ef7c6de733d882eb5 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 99 124 5.3E-16 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSH58p_02205 18d3cabdae23890ef7c6de733d882eb5 253 PIRSF PIRSF006648 10 250 9.3E-31 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSH58p_02205 18d3cabdae23890ef7c6de733d882eb5 253 Pfam PF01061 ABC-2 type transporter 6 216 2.5E-32 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TSH58p_32415 ac0b9e51ad8813bb22b2f96edfbf2a95 122 SMART SM00530 66 121 4.7E-15 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_32415 ac0b9e51ad8813bb22b2f96edfbf2a95 122 Gene3D G3DSA:1.10.260.40 44 122 7.7E-17 T 14-10-2018 TSH58p_32415 ac0b9e51ad8813bb22b2f96edfbf2a95 122 SUPERFAMILY SSF47413 67 121 7.78E-15 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_32415 ac0b9e51ad8813bb22b2f96edfbf2a95 122 Pfam PF01381 Helix-turn-helix 70 121 2.8E-14 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_09210 8d85de01c4fa0752c2dcf2390354fd88 160 Pfam PF07486 Cell Wall Hydrolase 41 156 1.7E-17 T 14-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 TSH58p_09210 8d85de01c4fa0752c2dcf2390354fd88 160 Gene3D G3DSA:1.10.10.2520 26 119 2.5E-10 T 14-10-2018 TSH58p_22100 388fa875a951e778373c06e6bd0db98a 621 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 610 4.0E-249 T 14-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TSH58p_22100 388fa875a951e778373c06e6bd0db98a 621 SUPERFAMILY SSF52016 421 612 1.1E-59 T 14-10-2018 TSH58p_22100 388fa875a951e778373c06e6bd0db98a 621 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 610 44.873 T 14-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TSH58p_22100 388fa875a951e778373c06e6bd0db98a 621 Gene3D G3DSA:3.50.30.80 421 573 1.2E-55 T 14-10-2018 TSH58p_22100 388fa875a951e778373c06e6bd0db98a 621 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 509 520 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TSH58p_22100 388fa875a951e778373c06e6bd0db98a 621 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TSH58p_22100 388fa875a951e778373c06e6bd0db98a 621 Pfam PF00920 Dehydratase family 34 607 6.9E-219 T 14-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TSH58p_22100 388fa875a951e778373c06e6bd0db98a 621 SUPERFAMILY SSF143975 3 420 9.15E-134 T 14-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TSH58p_16060 de1fb92ff03537c31a741c63597177fb 245 Pfam PF02104 SURF1 family 23 227 3.7E-43 T 14-10-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_14225 a9bf0e03b18d216d56cd51c44f47e6f7 121 Gene3D G3DSA:3.40.50.2300 1 119 3.8E-37 T 14-10-2018 TSH58p_14225 a9bf0e03b18d216d56cd51c44f47e6f7 121 SMART SM00448 1 115 1.1E-36 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_14225 a9bf0e03b18d216d56cd51c44f47e6f7 121 Pfam PF00072 Response regulator receiver domain 3 116 6.2E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_14225 a9bf0e03b18d216d56cd51c44f47e6f7 121 SUPERFAMILY SSF52172 1 120 1.99E-36 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_12975 cb50e006333909cb43e593abcadf9ee1 389 Pfam PF16822 SGNH hydrolase-like domain, acetyltransferase AlgX 235 356 6.8E-7 T 14-10-2018 IPR031811 AlgX/AlgJ, SGNH hydrolase-like domain TSH58p_24495 655e569e6db74e71555d32dee017a63c 185 PIRSF PIRSF002721 48 185 6.8E-32 T 14-10-2018 IPR016364 Surface antigen, Rickettsia type TSH58p_24495 655e569e6db74e71555d32dee017a63c 185 Pfam PF16998 17 kDa outer membrane surface antigen 96 183 2.8E-11 T 14-10-2018 IPR032635 Surface antigen domain TSH58p_15330 1eabcf71d3532bf6d2414b90a5adac5c 264 Pfam PF10002 Predicted membrane protein (DUF2243) 21 159 8.2E-47 T 14-10-2018 IPR018719 Protein of unknown function DUF2243, membrane TSH58p_15610 b8a34a2a92360607ee5a7e292ae56444 127 Pfam PF07750 GcrA cell cycle regulator 55 112 1.8E-21 T 14-10-2018 IPR011681 GcrA cell cycle regulator TSH58p_15610 b8a34a2a92360607ee5a7e292ae56444 127 Pfam PF07750 GcrA cell cycle regulator 1 54 4.4E-22 T 14-10-2018 IPR011681 GcrA cell cycle regulator TSH58p_15610 b8a34a2a92360607ee5a7e292ae56444 127 Gene3D G3DSA:1.10.10.60 2 46 1.7E-7 T 14-10-2018 TSH58p_22725 f0a1b4abadb4b4933ff5bdd608187f59 651 Pfam PF05876 Phage terminase large subunit (GpA) 53 589 4.8E-136 T 14-10-2018 IPR008866 Bacteriophage lambda, GpA TSH58p_22725 f0a1b4abadb4b4933ff5bdd608187f59 651 Gene3D G3DSA:3.40.50.300 27 220 9.3E-7 T 14-10-2018 TSH58p_13110 dc2590a2d72a29c8ffe3a5764b2fc6de 280 Hamap MF_00811 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 3 280 55.581 T 14-10-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 TSH58p_13110 dc2590a2d72a29c8ffe3a5764b2fc6de 280 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 136 169 7.1E-4 T 14-10-2018 IPR001451 Hexapeptide repeat TSH58p_13110 dc2590a2d72a29c8ffe3a5764b2fc6de 280 SUPERFAMILY SSF51161 6 264 2.36E-63 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily TSH58p_13110 dc2590a2d72a29c8ffe3a5764b2fc6de 280 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 137 165 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 TSH58p_13110 dc2590a2d72a29c8ffe3a5764b2fc6de 280 Gene3D G3DSA:1.10.166.10 3 71 3.5E-26 T 14-10-2018 IPR037133 Tetrahydrodipicolinate-N-succinyltransferase, N-terminal domain superfamily KEGG: 00300+2.3.1.117 TSH58p_13110 dc2590a2d72a29c8ffe3a5764b2fc6de 280 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 178 213 8.8E-12 T 14-10-2018 IPR001451 Hexapeptide repeat TSH58p_13110 dc2590a2d72a29c8ffe3a5764b2fc6de 280 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 5 70 3.5E-23 T 14-10-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 TSH58p_13110 dc2590a2d72a29c8ffe3a5764b2fc6de 280 Gene3D G3DSA:2.160.10.10 90 265 2.9E-52 T 14-10-2018 TSH58p_13110 dc2590a2d72a29c8ffe3a5764b2fc6de 280 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 6 279 2.3E-127 T 14-10-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 TSH58p_05250 3ae35e7c66ffb33ddcafbce66f32fcd8 435 SUPERFAMILY SSF51735 9 147 2.4E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_05250 3ae35e7c66ffb33ddcafbce66f32fcd8 435 SUPERFAMILY SSF55021 354 423 2.78E-10 T 14-10-2018 TSH58p_05250 3ae35e7c66ffb33ddcafbce66f32fcd8 435 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 190 212 - T 14-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 TSH58p_05250 3ae35e7c66ffb33ddcafbce66f32fcd8 435 PIRSF PIRSF000098 7 435 4.4E-159 T 14-10-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 TSH58p_05250 3ae35e7c66ffb33ddcafbce66f32fcd8 435 Gene3D G3DSA:3.30.360.10 143 349 1.9E-156 T 14-10-2018 TSH58p_05250 3ae35e7c66ffb33ddcafbce66f32fcd8 435 Gene3D G3DSA:3.40.50.720 10 344 1.9E-156 T 14-10-2018 TSH58p_05250 3ae35e7c66ffb33ddcafbce66f32fcd8 435 Pfam PF01842 ACT domain 355 418 6.7E-8 T 14-10-2018 IPR002912 ACT domain TSH58p_05250 3ae35e7c66ffb33ddcafbce66f32fcd8 435 Pfam PF00742 Homoserine dehydrogenase 144 322 3.6E-65 T 14-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 TSH58p_05250 3ae35e7c66ffb33ddcafbce66f32fcd8 435 SUPERFAMILY SSF55347 144 309 5.56E-53 T 14-10-2018 TSH58p_05250 3ae35e7c66ffb33ddcafbce66f32fcd8 435 Gene3D G3DSA:3.30.70.260 350 423 1.9E-156 T 14-10-2018 TSH58p_05250 3ae35e7c66ffb33ddcafbce66f32fcd8 435 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 16 135 3.7E-17 T 14-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 TSH58p_17030 729a1fc514e326165702ad0253159096 147 Pfam PF05239 PRC-barrel domain 55 120 1.5E-11 T 14-10-2018 IPR027275 PRC-barrel domain TSH58p_17030 729a1fc514e326165702ad0253159096 147 SUPERFAMILY SSF50346 38 133 3.14E-16 T 14-10-2018 IPR011033 PRC-barrel-like superfamily TSH58p_17030 729a1fc514e326165702ad0253159096 147 Gene3D G3DSA:2.30.30.240 35 129 4.2E-20 T 14-10-2018 TSH58p_18875 f3f7ac38042875585121467a8187e8f7 238 SUPERFAMILY SSF46689 5 66 1.59E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_18875 f3f7ac38042875585121467a8187e8f7 238 ProSitePatterns PS01081 TetR-type HTH domain signature. 25 55 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site TSH58p_18875 f3f7ac38042875585121467a8187e8f7 238 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 8.6E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_18875 f3f7ac38042875585121467a8187e8f7 238 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 8.6E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_18875 f3f7ac38042875585121467a8187e8f7 238 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 9.7E-19 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_18875 f3f7ac38042875585121467a8187e8f7 238 Gene3D G3DSA:1.10.357.10 1 208 2.4E-28 T 14-10-2018 TSH58p_02785 9c3021a34ef576751a8f031abf2fac6b 129 Pfam PF00034 Cytochrome c 43 125 2.4E-7 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_02785 9c3021a34ef576751a8f031abf2fac6b 129 SUPERFAMILY SSF46626 19 125 8.47E-14 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_02785 9c3021a34ef576751a8f031abf2fac6b 129 Gene3D G3DSA:1.10.760.10 9 129 4.2E-14 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_11895 816d4bf273c3a5aa763535c7c2af3dc5 316 SUPERFAMILY SSF53474 5 299 7.57E-58 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_11895 816d4bf273c3a5aa763535c7c2af3dc5 316 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 11 312 2.1E-118 T 14-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 TSH58p_11895 816d4bf273c3a5aa763535c7c2af3dc5 316 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 6.3E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_11895 816d4bf273c3a5aa763535c7c2af3dc5 316 PRINTS PR00111 Alpha/beta hydrolase fold signature 122 135 6.3E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_11895 816d4bf273c3a5aa763535c7c2af3dc5 316 PRINTS PR00111 Alpha/beta hydrolase fold signature 62 77 6.3E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_11895 816d4bf273c3a5aa763535c7c2af3dc5 316 Gene3D G3DSA:3.40.50.1820 3 315 3.0E-99 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_11895 816d4bf273c3a5aa763535c7c2af3dc5 316 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 39 47 1.4E-12 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 TSH58p_11895 816d4bf273c3a5aa763535c7c2af3dc5 316 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 108 122 1.4E-12 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 TSH58p_11895 816d4bf273c3a5aa763535c7c2af3dc5 316 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 65 76 1.4E-12 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 TSH58p_11895 816d4bf273c3a5aa763535c7c2af3dc5 316 PIRSF PIRSF006431 1 316 1.4E-130 T 14-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 TSH58p_11895 816d4bf273c3a5aa763535c7c2af3dc5 316 Pfam PF00561 alpha/beta hydrolase fold 38 297 5.3E-28 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_02995 545d21327baab7dfedc1fb0f9421e538 271 Gene3D G3DSA:3.40.50.1110 70 263 4.9E-36 T 14-10-2018 IPR036514 SGNH hydrolase superfamily TSH58p_02995 545d21327baab7dfedc1fb0f9421e538 271 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 73 245 1.8E-18 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain TSH58p_02995 545d21327baab7dfedc1fb0f9421e538 271 SUPERFAMILY SSF52266 68 258 3.66E-37 T 14-10-2018 TSH58p_21585 9505d365ba3b7271b91556e9cb726374 485 Pfam PF00361 Proton-conducting membrane transporter 118 414 2.8E-49 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_21585 9505d365ba3b7271b91556e9cb726374 485 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 374 400 1.8E-9 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_21585 9505d365ba3b7271b91556e9cb726374 485 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 233 257 1.8E-9 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_21585 9505d365ba3b7271b91556e9cb726374 485 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 322 341 1.8E-9 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_20290 c9566f96982ed8044c77f1bcbeef2a56 216 Pfam PF01914 MarC family integral membrane protein 2 208 4.5E-43 T 14-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 TSH58p_20290 c9566f96982ed8044c77f1bcbeef2a56 216 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 2 205 4.7E-43 T 14-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 TSH58p_18690 3421f3a90edf388d55ae26bc412947a1 237 Gene3D G3DSA:3.40.50.2300 1 122 2.9E-36 T 14-10-2018 TSH58p_18690 3421f3a90edf388d55ae26bc412947a1 237 Gene3D G3DSA:1.10.10.10 128 236 2.9E-33 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_18690 3421f3a90edf388d55ae26bc412947a1 237 SUPERFAMILY SSF52172 1 125 2.28E-40 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_18690 3421f3a90edf388d55ae26bc412947a1 237 Pfam PF00072 Response regulator receiver domain 3 112 1.0E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_18690 3421f3a90edf388d55ae26bc412947a1 237 SMART SM00862 154 230 2.2E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_18690 3421f3a90edf388d55ae26bc412947a1 237 SMART SM00448 1 111 1.3E-43 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_18690 3421f3a90edf388d55ae26bc412947a1 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 230 9.6E-23 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSH58p_18690 3421f3a90edf388d55ae26bc412947a1 237 SUPERFAMILY SSF46894 132 231 1.73E-25 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_00320 f836283b5cd47e2d81af43467fa8a53b 720 SUPERFAMILY SSF53448 456 694 4.22E-9 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_00320 f836283b5cd47e2d81af43467fa8a53b 720 Gene3D G3DSA:3.90.550.10 458 697 3.1E-7 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_23940 7b6d8032e63b274478a38c27213ab6f4 243 Pfam PF00293 NUDIX domain 56 175 4.3E-15 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TSH58p_23940 7b6d8032e63b274478a38c27213ab6f4 243 SUPERFAMILY SSF55811 55 208 2.3E-37 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TSH58p_23940 7b6d8032e63b274478a38c27213ab6f4 243 Gene3D G3DSA:3.90.79.10 45 214 9.4E-53 T 14-10-2018 TSH58p_06735 13ac19c606e9472b3cfada28574df454 640 ProSitePatterns PS00455 Putative AMP-binding domain signature. 242 253 - T 14-10-2018 IPR020845 AMP-binding, conserved site TSH58p_06735 13ac19c606e9472b3cfada28574df454 640 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 9 63 6.8E-24 T 14-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 TSH58p_06735 13ac19c606e9472b3cfada28574df454 640 Pfam PF13193 AMP-binding enzyme C-terminal domain 516 594 1.2E-22 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSH58p_06735 13ac19c606e9472b3cfada28574df454 640 Gene3D G3DSA:3.30.300.30 502 631 4.4E-22 T 14-10-2018 TSH58p_06735 13ac19c606e9472b3cfada28574df454 640 SUPERFAMILY SSF56801 4 623 5.36E-161 T 14-10-2018 TSH58p_06735 13ac19c606e9472b3cfada28574df454 640 Pfam PF00501 AMP-binding enzyme 74 506 8.3E-87 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSH58p_06735 13ac19c606e9472b3cfada28574df454 640 Gene3D G3DSA:3.40.50.12780 34 499 3.8E-108 T 14-10-2018 TSH58p_16795 47f51c198479109cf5e8059b8967f83f 345 Pfam PF00990 Diguanylate cyclase, GGDEF domain 177 336 1.4E-43 T 14-10-2018 IPR000160 GGDEF domain TSH58p_16795 47f51c198479109cf5e8059b8967f83f 345 SUPERFAMILY SSF55073 182 338 9.42E-46 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_16795 47f51c198479109cf5e8059b8967f83f 345 SMART SM00267 166 340 4.3E-58 T 14-10-2018 IPR000160 GGDEF domain TSH58p_16795 47f51c198479109cf5e8059b8967f83f 345 Gene3D G3DSA:3.30.70.270 165 341 2.2E-53 T 14-10-2018 TSH58p_16795 47f51c198479109cf5e8059b8967f83f 345 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 175 339 2.0E-49 T 14-10-2018 IPR000160 GGDEF domain TSH58p_23095 b24da0e0fb1d143295437bb8a7ce3f88 426 Gene3D G3DSA:3.20.20.300 73 419 1.3E-80 T 14-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 TSH58p_23095 b24da0e0fb1d143295437bb8a7ce3f88 426 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 105 417 1.1E-51 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TSH58p_23095 b24da0e0fb1d143295437bb8a7ce3f88 426 SUPERFAMILY SSF51445 98 417 8.74E-56 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_08225 b1403122693aaefebf3b53a17b3c6891 327 Pfam PF00676 Dehydrogenase E1 component 19 314 4.9E-101 T 14-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 TSH58p_08225 b1403122693aaefebf3b53a17b3c6891 327 SUPERFAMILY SSF52518 3 326 3.75E-97 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_08225 b1403122693aaefebf3b53a17b3c6891 327 Gene3D G3DSA:3.40.50.970 2 327 2.4E-119 T 14-10-2018 TSH58p_12465 261f0f9ccc45d563a0956678852492b4 172 Pfam PF13302 Acetyltransferase (GNAT) domain 14 149 1.0E-30 T 14-10-2018 IPR000182 GNAT domain TSH58p_12465 261f0f9ccc45d563a0956678852492b4 172 SUPERFAMILY SSF55729 7 165 5.06E-40 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_12465 261f0f9ccc45d563a0956678852492b4 172 Gene3D G3DSA:3.40.630.30 6 170 5.0E-42 T 14-10-2018 TSH58p_14400 cf6a5dedaadcee6c11adb2682af9eacd 184 Pfam PF00583 Acetyltransferase (GNAT) family 49 134 2.3E-7 T 14-10-2018 IPR000182 GNAT domain TSH58p_14400 cf6a5dedaadcee6c11adb2682af9eacd 184 Gene3D G3DSA:3.40.630.30 2 177 3.9E-29 T 14-10-2018 TSH58p_14400 cf6a5dedaadcee6c11adb2682af9eacd 184 SUPERFAMILY SSF55729 4 139 1.95E-18 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_15430 aef930d0c927a14fc83f1d2ec27ec2ae 317 SUPERFAMILY SSF158791 242 304 9.02E-7 T 14-10-2018 TSH58p_19140 7291eae11d2210d205c3b5fec17da5b7 101 Pfam PF10135 Rod binding protein 40 85 4.9E-9 T 14-10-2018 IPR019301 Flagellar protein FlgJ, N-terminal TSH58p_08270 f694fe06c14f4a685970369ccbe5a862 294 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 276 4.3E-38 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_17330 638366f2ba3b1d34b19e09d802f4145a 177 Pfam PF13411 MerR HTH family regulatory protein 15 82 8.1E-24 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_17330 638366f2ba3b1d34b19e09d802f4145a 177 SMART SM00422 15 84 0.0015 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSH58p_17330 638366f2ba3b1d34b19e09d802f4145a 177 SUPERFAMILY SSF46955 15 85 8.7E-15 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily TSH58p_17330 638366f2ba3b1d34b19e09d802f4145a 177 Gene3D G3DSA:1.10.1660.10 8 83 7.4E-21 T 14-10-2018 TSH58p_01045 9ca20d589614e2128c09811a6217e3fb 846 Pfam PF12704 MacB-like periplasmic core domain 26 200 1.4E-6 T 14-10-2018 IPR025857 MacB-like periplasmic core domain TSH58p_11480 ef0053f8b06919b173599fa68497853d 329 SUPERFAMILY SSF51735 106 294 1.78E-60 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_11480 ef0053f8b06919b173599fa68497853d 329 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 19 324 4.8E-32 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 TSH58p_11480 ef0053f8b06919b173599fa68497853d 329 Gene3D G3DSA:3.40.50.720 9 303 5.2E-112 T 14-10-2018 TSH58p_11480 ef0053f8b06919b173599fa68497853d 329 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 154 181 - T 14-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 TSH58p_11480 ef0053f8b06919b173599fa68497853d 329 Gene3D G3DSA:3.40.50.720 106 289 5.2E-112 T 14-10-2018 TSH58p_11480 ef0053f8b06919b173599fa68497853d 329 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 114 293 3.0E-58 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TSH58p_11480 ef0053f8b06919b173599fa68497853d 329 SUPERFAMILY SSF52283 6 139 1.1E-38 T 14-10-2018 TSH58p_04090 03cf3b27352ef32fc5ccad41fd3fef99 148 Pfam PF01668 SmpB protein 3 145 3.3E-57 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 TSH58p_04090 03cf3b27352ef32fc5ccad41fd3fef99 148 Gene3D G3DSA:2.40.280.10 1 124 2.9E-44 T 14-10-2018 IPR023620 Small protein B TSH58p_04090 03cf3b27352ef32fc5ccad41fd3fef99 148 ProSitePatterns PS01317 SsrA-binding protein. 20 32 - T 14-10-2018 IPR020081 SsrA-binding protein, conserved site TSH58p_04090 03cf3b27352ef32fc5ccad41fd3fef99 148 Hamap MF_00023 SsrA-binding protein [smpB]. 1 148 68.717 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 TSH58p_04090 03cf3b27352ef32fc5ccad41fd3fef99 148 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 3 127 2.0E-40 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 TSH58p_04090 03cf3b27352ef32fc5ccad41fd3fef99 148 TIGRFAM TIGR00086 smpB: SsrA-binding protein 2 144 1.1E-52 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 TSH58p_04090 03cf3b27352ef32fc5ccad41fd3fef99 148 SUPERFAMILY SSF74982 2 127 2.62E-46 T 14-10-2018 IPR023620 Small protein B TSH58p_31960 37580cb99cbe1005f38297466c0bc06f 340 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 64 78 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 TSH58p_31960 37580cb99cbe1005f38297466c0bc06f 340 SUPERFAMILY SSF51735 142 309 3.71E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_31960 37580cb99cbe1005f38297466c0bc06f 340 Pfam PF00107 Zinc-binding dehydrogenase 179 302 5.5E-32 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TSH58p_31960 37580cb99cbe1005f38297466c0bc06f 340 Gene3D G3DSA:3.90.180.10 16 336 1.5E-133 T 14-10-2018 TSH58p_31960 37580cb99cbe1005f38297466c0bc06f 340 Gene3D G3DSA:3.40.50.720 152 289 1.5E-133 T 14-10-2018 TSH58p_31960 37580cb99cbe1005f38297466c0bc06f 340 SMART SM00829 8 338 1.4E-8 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TSH58p_31960 37580cb99cbe1005f38297466c0bc06f 340 SUPERFAMILY SSF50129 1 174 1.67E-56 T 14-10-2018 IPR011032 GroES-like superfamily TSH58p_31960 37580cb99cbe1005f38297466c0bc06f 340 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 135 9.2E-33 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TSH58p_31150 75ad6d5ac7f529cdee8f2e84e12a606c 385 Pfam PF01546 Peptidase family M20/M25/M40 69 382 8.6E-34 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 TSH58p_31150 75ad6d5ac7f529cdee8f2e84e12a606c 385 SUPERFAMILY SSF53187 5 385 4.57E-57 T 14-10-2018 TSH58p_31150 75ad6d5ac7f529cdee8f2e84e12a606c 385 Gene3D G3DSA:3.30.70.360 177 293 6.0E-100 T 14-10-2018 TSH58p_31150 75ad6d5ac7f529cdee8f2e84e12a606c 385 Pfam PF07687 Peptidase dimerisation domain 173 281 1.2E-18 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain TSH58p_31150 75ad6d5ac7f529cdee8f2e84e12a606c 385 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 68 77 - T 14-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 TSH58p_31150 75ad6d5ac7f529cdee8f2e84e12a606c 385 Gene3D G3DSA:3.40.630.10 14 370 6.0E-100 T 14-10-2018 TSH58p_31150 75ad6d5ac7f529cdee8f2e84e12a606c 385 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 103 140 - T 14-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 TSH58p_31150 75ad6d5ac7f529cdee8f2e84e12a606c 385 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 9 380 7.9E-121 T 14-10-2018 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 TSH58p_31150 75ad6d5ac7f529cdee8f2e84e12a606c 385 SUPERFAMILY SSF55031 177 285 3.74E-19 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TSH58p_26635 5d47c4c2bd84d893be87ea49a6604788 560 Gene3D G3DSA:3.40.50.300 327 556 1.5E-63 T 14-10-2018 TSH58p_26635 5d47c4c2bd84d893be87ea49a6604788 560 Gene3D G3DSA:1.20.1560.10 12 320 1.3E-29 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_26635 5d47c4c2bd84d893be87ea49a6604788 560 SUPERFAMILY SSF52540 328 544 2.21E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_26635 5d47c4c2bd84d893be87ea49a6604788 560 SUPERFAMILY SSF90123 14 313 1.15E-28 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_26635 5d47c4c2bd84d893be87ea49a6604788 560 Pfam PF00664 ABC transporter transmembrane region 125 282 1.7E-8 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TSH58p_26635 5d47c4c2bd84d893be87ea49a6604788 560 SMART SM00382 359 546 1.1E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_26635 5d47c4c2bd84d893be87ea49a6604788 560 Pfam PF00005 ABC transporter 350 498 4.6E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_24195 1788a7d67cfa2e38e434b550c248147c 320 Gene3D G3DSA:2.40.440.10 13 212 6.1E-49 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like TSH58p_24195 1788a7d67cfa2e38e434b550c248147c 320 SUPERFAMILY SSF141523 50 181 4.71E-30 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like TSH58p_24195 1788a7d67cfa2e38e434b550c248147c 320 Pfam PF03734 L,D-transpeptidase catalytic domain 53 181 1.6E-20 T 14-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 TSH58p_15900 6c616bdee2798eb73648268452d0039a 454 Pfam PF03631 Virulence factor BrkB 19 268 1.5E-49 T 14-10-2018 IPR017039 Virulence factor BrkB TSH58p_15900 6c616bdee2798eb73648268452d0039a 454 Hamap MF_00672 UPF0761 membrane protein YihY [yihY]. 1 300 21.137 T 14-10-2018 IPR023679 Uncharacterised protein family UPF0761, bacterial TSH58p_15900 6c616bdee2798eb73648268452d0039a 454 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 15 268 1.7E-62 T 14-10-2018 IPR017039 Virulence factor BrkB TSH58p_19450 4e851131d831cdfaea159969873e026e 290 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 275 5.6E-41 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_23860 58d24804494dc092a92f3d409b6ecda7 288 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 75 91 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site TSH58p_23860 58d24804494dc092a92f3d409b6ecda7 288 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 207 219 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site TSH58p_23860 58d24804494dc092a92f3d409b6ecda7 288 Gene3D G3DSA:1.10.600.10 1 288 2.7E-98 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily TSH58p_23860 58d24804494dc092a92f3d409b6ecda7 288 Pfam PF00348 Polyprenyl synthetase 26 254 8.5E-54 T 14-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 TSH58p_23860 58d24804494dc092a92f3d409b6ecda7 288 SUPERFAMILY SSF48576 3 280 6.66E-82 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily TSH58p_05910 e03015fed80a5fe87f8f19199609721d 187 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 40 181 8.3E-76 T 14-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05910 e03015fed80a5fe87f8f19199609721d 187 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 67 175 8.7E-22 T 14-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05910 e03015fed80a5fe87f8f19199609721d 187 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 147 163 - T 14-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05910 e03015fed80a5fe87f8f19199609721d 187 Gene3D G3DSA:3.40.50.12280 24 187 1.3E-78 T 14-10-2018 TSH58p_05910 e03015fed80a5fe87f8f19199609721d 187 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 29 180 41.069 T 14-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05910 e03015fed80a5fe87f8f19199609721d 187 SUPERFAMILY SSF56770 38 183 3.66E-66 T 14-10-2018 TSH58p_14240 2ac95fc444d1178d95e8b9a2f0ade467 272 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 5 236 37.221 T 14-10-2018 IPR017689 Outer membrane protein assembly factor BamD TSH58p_14240 2ac95fc444d1178d95e8b9a2f0ade467 272 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 8 242 2.2E-89 T 14-10-2018 IPR017689 Outer membrane protein assembly factor BamD TSH58p_14240 2ac95fc444d1178d95e8b9a2f0ade467 272 Pfam PF13525 Outer membrane lipoprotein 34 229 1.3E-56 T 14-10-2018 IPR039565 Outer membrane lipoprotein BamD-like TSH58p_14240 2ac95fc444d1178d95e8b9a2f0ade467 272 SUPERFAMILY SSF48452 53 228 4.68E-13 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_14240 2ac95fc444d1178d95e8b9a2f0ade467 272 Gene3D G3DSA:1.25.40.10 34 247 1.1E-61 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_03895 411d53c8b61ca6b22e2e84b543d1d2bd 356 Gene3D G3DSA:3.40.640.10 54 258 9.8E-56 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_03895 411d53c8b61ca6b22e2e84b543d1d2bd 356 TIGRFAM TIGR01140 L_thr_O3P_dcar: threonine-phosphate decarboxylase 24 344 6.3E-106 T 14-10-2018 IPR005860 L-threonine-O-3-phosphate decarboxylase GO:0003824|GO:0009236 KEGG: 00860+4.1.1.81|MetaCyc: PWY-5443 TSH58p_03895 411d53c8b61ca6b22e2e84b543d1d2bd 356 SUPERFAMILY SSF53383 24 340 1.51E-55 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_03895 411d53c8b61ca6b22e2e84b543d1d2bd 356 Gene3D G3DSA:3.90.1150.10 42 331 9.8E-56 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_03895 411d53c8b61ca6b22e2e84b543d1d2bd 356 Pfam PF00155 Aminotransferase class I and II 73 335 9.1E-35 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSH58p_29870 d711c8421c793f5580c450eddcf5d0eb 97 Pfam PF04977 Septum formation initiator 6 85 1.2E-16 T 14-10-2018 IPR007060 Septum formation initiator FtsL/DivIC TSH58p_07815 b494c6559a5a6a32c686d9f1ca2f6f87 465 Gene3D G3DSA:3.40.50.2000 22 456 1.8E-163 T 14-10-2018 TSH58p_07815 b494c6559a5a6a32c686d9f1ca2f6f87 465 SUPERFAMILY SSF53756 2 461 2.64E-147 T 14-10-2018 TSH58p_07815 b494c6559a5a6a32c686d9f1ca2f6f87 465 Pfam PF00982 Glycosyltransferase family 20 18 460 8.8E-137 T 14-10-2018 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 KEGG: 00500+2.4.1.15 TSH58p_07815 b494c6559a5a6a32c686d9f1ca2f6f87 465 TIGRFAM TIGR02400 trehalose_OtsA: alpha,alpha-trehalose-phosphate synthase (UDP-forming) 3 460 2.3E-179 T 14-10-2018 IPR012766 Alpha,alpha-trehalose-phosphate synthase GO:0003825|GO:0005992 KEGG: 00500+2.4.1.15 TSH58p_07815 b494c6559a5a6a32c686d9f1ca2f6f87 465 Gene3D G3DSA:3.40.50.2000 237 445 1.8E-163 T 14-10-2018 TSH58p_29780 3ad47a9a0b30327dc31b5fb2dd6d82a5 269 Pfam PF07007 Lysozyme inhibitor LprI 40 119 2.6E-6 T 14-10-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal TSH58p_29780 3ad47a9a0b30327dc31b5fb2dd6d82a5 269 Gene3D G3DSA:1.20.1270.180 23 131 5.0E-6 T 14-10-2018 TSH58p_22445 0467328c574669a55b372a24516a8972 260 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 12 247 4.3E-67 T 14-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TSH58p_22445 0467328c574669a55b372a24516a8972 260 Gene3D G3DSA:3.40.1210.10 11 260 2.7E-91 T 14-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TSH58p_22445 0467328c574669a55b372a24516a8972 260 SUPERFAMILY SSF64167 12 259 1.83E-83 T 14-10-2018 TSH58p_22445 0467328c574669a55b372a24516a8972 260 Pfam PF01975 Survival protein SurE 13 196 2.3E-60 T 14-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TSH58p_22445 0467328c574669a55b372a24516a8972 260 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 11 260 37.359 T 14-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TSH58p_19025 cdff8544eb8a05e65dafef067058eb55 394 Pfam PF00529 HlyD membrane-fusion protein of T1SS 297 363 1.1E-9 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 TSH58p_19025 cdff8544eb8a05e65dafef067058eb55 394 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 64 296 7.3E-14 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain TSH58p_19025 cdff8544eb8a05e65dafef067058eb55 394 Gene3D G3DSA:2.40.50.100 65 209 3.0E-109 T 14-10-2018 TSH58p_19025 cdff8544eb8a05e65dafef067058eb55 394 Gene3D G3DSA:2.40.30.170 52 306 3.0E-109 T 14-10-2018 TSH58p_19025 cdff8544eb8a05e65dafef067058eb55 394 Gene3D G3DSA:1.10.287.470 100 173 3.0E-109 T 14-10-2018 TSH58p_19025 cdff8544eb8a05e65dafef067058eb55 394 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 41 378 1.8E-87 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 TSH58p_19025 cdff8544eb8a05e65dafef067058eb55 394 SUPERFAMILY SSF111369 53 303 1.03E-83 T 14-10-2018 TSH58p_19025 cdff8544eb8a05e65dafef067058eb55 394 Gene3D G3DSA:2.40.420.20 307 376 3.0E-109 T 14-10-2018 TSH58p_17170 e84755c0ef83a09078f401a177322a84 294 SUPERFAMILY SSF53167 8 275 9.88E-92 T 14-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TSH58p_17170 e84755c0ef83a09078f401a177322a84 294 Gene3D G3DSA:3.40.50.1580 2 290 6.2E-102 T 14-10-2018 TSH58p_17170 e84755c0ef83a09078f401a177322a84 294 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 8 275 41.865 T 14-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 TSH58p_17170 e84755c0ef83a09078f401a177322a84 294 Pfam PF01048 Phosphorylase superfamily 10 239 1.5E-44 T 14-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TSH58p_17170 e84755c0ef83a09078f401a177322a84 294 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 10 246 4.1E-95 T 14-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 TSH58p_17170 e84755c0ef83a09078f401a177322a84 294 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 56 96 - T 14-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 TSH58p_05315 25bfd340ddefdd907fdbe92a8599dfcf 172 SUPERFAMILY SSF51735 12 143 1.79E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_05315 25bfd340ddefdd907fdbe92a8599dfcf 172 Gene3D G3DSA:3.40.50.720 7 151 7.9E-45 T 14-10-2018 TSH58p_05315 25bfd340ddefdd907fdbe92a8599dfcf 172 SMART SM00881 19 114 9.0E-31 T 14-10-2018 IPR003781 CoA-binding GO:0048037 TSH58p_05315 25bfd340ddefdd907fdbe92a8599dfcf 172 Pfam PF13380 CoA binding domain 24 140 4.1E-41 T 14-10-2018 IPR003781 CoA-binding GO:0048037 TSH58p_29250 4123e8c6cd063d524da7a8ef3e3423f0 60 Pfam PF04325 Protein of unknown function (DUF465) 8 52 2.0E-12 T 14-10-2018 IPR007420 Protein of unknown function DUF465 TSH58p_29250 4123e8c6cd063d524da7a8ef3e3423f0 60 Gene3D G3DSA:1.20.58.660 1 59 3.3E-7 T 14-10-2018 TSH58p_03360 cdd2389da6da4c0e7e76f1f936a7e6ca 216 Gene3D G3DSA:3.20.20.70 10 214 1.5E-58 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_03360 cdd2389da6da4c0e7e76f1f936a7e6ca 216 SUPERFAMILY SSF51569 11 212 4.94E-55 T 14-10-2018 TSH58p_03360 cdd2389da6da4c0e7e76f1f936a7e6ca 216 Pfam PF01081 KDPG and KHG aldolase 15 189 1.1E-28 T 14-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 TSH58p_11740 85706f2dea2d0cc7026271479c4f3509 418 SUPERFAMILY SSF52507 6 184 6.93E-61 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TSH58p_11740 85706f2dea2d0cc7026271479c4f3509 418 Gene3D G3DSA:3.40.50.10300 189 407 4.2E-72 T 14-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TSH58p_11740 85706f2dea2d0cc7026271479c4f3509 418 Pfam PF02441 Flavoprotein 10 182 5.0E-44 T 14-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 TSH58p_11740 85706f2dea2d0cc7026271479c4f3509 418 SUPERFAMILY SSF102645 191 406 1.31E-72 T 14-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TSH58p_11740 85706f2dea2d0cc7026271479c4f3509 418 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 8 401 4.0E-121 T 14-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 TSH58p_11740 85706f2dea2d0cc7026271479c4f3509 418 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 193 377 9.0E-66 T 14-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TSH58p_11740 85706f2dea2d0cc7026271479c4f3509 418 Gene3D G3DSA:3.40.50.1950 3 188 5.2E-60 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TSH58p_18240 2e0029ddd2163ab83d253065a58ae64d 294 Pfam PF00535 Glycosyl transferase family 2 1 137 5.9E-5 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_18240 2e0029ddd2163ab83d253065a58ae64d 294 SUPERFAMILY SSF53448 1 224 1.88E-21 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_18240 2e0029ddd2163ab83d253065a58ae64d 294 Gene3D G3DSA:3.90.550.10 1 253 4.2E-22 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_10425 c47ae01e44acb1c8ae40c209aaf4d3aa 220 SUPERFAMILY SSF89392 45 212 3.88E-25 T 14-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX TSH58p_10425 c47ae01e44acb1c8ae40c209aaf4d3aa 220 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 55 208 1.2E-27 T 14-10-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like TSH58p_10425 c47ae01e44acb1c8ae40c209aaf4d3aa 220 Gene3D G3DSA:2.50.20.10 41 215 6.9E-22 T 14-10-2018 TSH58p_13040 0584f05926ab9e5971d1a8a5e73720ae 63 Pfam PF11127 Protein of unknown function (DUF2892) 1 61 2.6E-23 T 14-10-2018 IPR021309 Protein of unknown function DUF2892 TSH58p_25205 64540716365567ca750fd25d2821989f 273 PIRSF PIRSF000883 1 246 5.7E-49 T 14-10-2018 IPR011152 Phosphoesterase MJ0912 TSH58p_25205 64540716365567ca750fd25d2821989f 273 SUPERFAMILY SSF56300 1 242 5.62E-47 T 14-10-2018 TSH58p_25205 64540716365567ca750fd25d2821989f 273 Gene3D G3DSA:3.60.21.10 1 245 3.5E-54 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like TSH58p_25205 64540716365567ca750fd25d2821989f 273 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 212 9.1E-25 T 14-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 TSH58p_13990 1160e107efa2b0a40f33a6f598023ca3 430 Pfam PF04285 Protein of unknown function (DUF444) 3 426 2.7E-171 T 14-10-2018 IPR006698 Uncharacterised protein family UPF0229 TSH58p_13990 1160e107efa2b0a40f33a6f598023ca3 430 Hamap MF_01232 UPF0229 protein YeaH [yeaH]. 1 428 37.587 T 14-10-2018 IPR006698 Uncharacterised protein family UPF0229 TSH58p_14520 8b1c5d02c58091abc251b7b489e73164 245 Gene3D G3DSA:3.30.530.20 75 219 7.4E-43 T 14-10-2018 IPR023393 START-like domain superfamily TSH58p_14520 8b1c5d02c58091abc251b7b489e73164 245 SUPERFAMILY SSF55961 81 215 6.09E-25 T 14-10-2018 TSH58p_14520 8b1c5d02c58091abc251b7b489e73164 245 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 84 206 1.3E-12 T 14-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 TSH58p_28615 c283feef9dd01fb695f309ff26569160 390 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 200 374 2.3E-21 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_28615 c283feef9dd01fb695f309ff26569160 390 SUPERFAMILY SSF161098 177 371 2.35E-34 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_28615 c283feef9dd01fb695f309ff26569160 390 Gene3D G3DSA:1.10.3720.10 172 378 3.1E-32 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_08785 159c0c27dc6ab904e22b62bb0967dd99 91 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 21 79 9.7E-8 T 14-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family TSH58p_08785 159c0c27dc6ab904e22b62bb0967dd99 91 Gene3D G3DSA:3.30.2310.20 16 89 9.5E-10 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily TSH58p_05705 288ea2f80e493008205a452e69e14bae 397 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 6 381 1.6E-84 T 14-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 TSH58p_05705 288ea2f80e493008205a452e69e14bae 397 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 3 381 34.664 T 14-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 TSH58p_05705 288ea2f80e493008205a452e69e14bae 397 Pfam PF02684 Lipid-A-disaccharide synthetase 6 361 7.4E-101 T 14-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 TSH58p_05705 288ea2f80e493008205a452e69e14bae 397 SUPERFAMILY SSF53756 6 379 3.18E-28 T 14-10-2018 TSH58p_25065 d2623758b60d8b9665df87f580df7556 358 Gene3D G3DSA:3.20.20.70 140 345 5.5E-6 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSH58p_25065 d2623758b60d8b9665df87f580df7556 358 Pfam PF04055 Radical SAM superfamily 71 248 5.7E-15 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSH58p_25065 d2623758b60d8b9665df87f580df7556 358 SUPERFAMILY SSF102114 65 264 9.03E-13 T 14-10-2018 TSH58p_25065 d2623758b60d8b9665df87f580df7556 358 SMART SM00729 67 295 1.2E-4 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSH58p_18130 1b7f4e68da01420b71f748e9dedbd3de 797 Gene3D G3DSA:3.40.50.2000 104 385 5.9E-21 T 14-10-2018 TSH58p_18130 1b7f4e68da01420b71f748e9dedbd3de 797 Gene3D G3DSA:3.40.50.150 587 720 4.0E-5 T 14-10-2018 TSH58p_18130 1b7f4e68da01420b71f748e9dedbd3de 797 Pfam PF13692 Glycosyl transferases group 1 206 354 9.7E-12 T 14-10-2018 TSH58p_18130 1b7f4e68da01420b71f748e9dedbd3de 797 SUPERFAMILY SSF53335 608 709 8.24E-6 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_18130 1b7f4e68da01420b71f748e9dedbd3de 797 SUPERFAMILY SSF53756 33 387 4.71E-28 T 14-10-2018 TSH58p_18130 1b7f4e68da01420b71f748e9dedbd3de 797 Gene3D G3DSA:3.40.50.2000 184 369 5.9E-21 T 14-10-2018 TSH58p_30865 9cccb4f23ebff6d744efd24fa965a5c8 315 SUPERFAMILY SSF103481 57 156 3.53E-16 T 14-10-2018 TSH58p_30865 9cccb4f23ebff6d744efd24fa965a5c8 315 Pfam PF00892 EamA-like transporter family 24 153 1.6E-13 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_30865 9cccb4f23ebff6d744efd24fa965a5c8 315 SUPERFAMILY SSF103481 196 296 5.1E-9 T 14-10-2018 TSH58p_30335 d2857825126dc761a1476e9a6b0a0fd5 203 SUPERFAMILY SSF160387 56 166 2.25E-31 T 14-10-2018 TSH58p_30335 d2857825126dc761a1476e9a6b0a0fd5 203 Gene3D G3DSA:3.30.70.2060 56 117 2.0E-21 T 14-10-2018 TSH58p_30335 d2857825126dc761a1476e9a6b0a0fd5 203 Gene3D G3DSA:3.30.70.2050 118 189 5.5E-20 T 14-10-2018 TSH58p_30335 d2857825126dc761a1476e9a6b0a0fd5 203 Pfam PF05573 NosL 18 164 6.1E-51 T 14-10-2018 IPR008719 Nitrous oxide reductase accessory protein NosL TSH58p_26880 7b5d34fad586a043ff458f768667bafe 279 SUPERFAMILY SSF46785 28 101 3.45E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_26880 7b5d34fad586a043ff458f768667bafe 279 Pfam PF09339 IclR helix-turn-helix domain 30 79 1.4E-13 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TSH58p_26880 7b5d34fad586a043ff458f768667bafe 279 Pfam PF01614 Bacterial transcriptional regulator 148 271 1.2E-28 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal TSH58p_26880 7b5d34fad586a043ff458f768667bafe 279 Gene3D G3DSA:1.10.10.10 22 98 3.2E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_26880 7b5d34fad586a043ff458f768667bafe 279 SUPERFAMILY SSF55781 99 271 2.09E-45 T 14-10-2018 TSH58p_26880 7b5d34fad586a043ff458f768667bafe 279 SMART SM00346 28 118 7.2E-21 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TSH58p_26880 7b5d34fad586a043ff458f768667bafe 279 Gene3D G3DSA:3.30.450.40 99 274 4.3E-51 T 14-10-2018 IPR029016 GAF-like domain superfamily TSH58p_04110 d355be810a63685069d0a55c67461577 326 Gene3D G3DSA:3.40.50.10330 11 141 1.6E-25 T 14-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 TSH58p_04110 d355be810a63685069d0a55c67461577 326 Pfam PF00781 Diacylglycerol kinase catalytic domain 20 142 1.6E-22 T 14-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 TSH58p_04110 d355be810a63685069d0a55c67461577 326 SUPERFAMILY SSF111331 17 314 5.56E-59 T 14-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily TSH58p_04110 d355be810a63685069d0a55c67461577 326 Gene3D G3DSA:2.60.200.40 142 306 1.1E-27 T 14-10-2018 TSH58p_04110 d355be810a63685069d0a55c67461577 326 SMART SM00046 18 146 0.0055 T 14-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 TSH58p_11055 e21b5f506fd7dc8e75d27910eaa650c8 214 Pfam PF01121 Dephospho-CoA kinase 3 175 3.0E-40 T 14-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 TSH58p_11055 e21b5f506fd7dc8e75d27910eaa650c8 214 Gene3D G3DSA:3.40.50.300 1 201 1.1E-59 T 14-10-2018 TSH58p_11055 e21b5f506fd7dc8e75d27910eaa650c8 214 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 3 174 4.2E-35 T 14-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 TSH58p_11055 e21b5f506fd7dc8e75d27910eaa650c8 214 SUPERFAMILY SSF52540 2 194 1.33E-30 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_11055 e21b5f506fd7dc8e75d27910eaa650c8 214 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 196 25.648 T 14-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 TSH58p_05085 209862aaa9bc5321cb7c89b4031d675c 250 Gene3D G3DSA:3.90.79.10 2 219 1.8E-55 T 14-10-2018 TSH58p_05085 209862aaa9bc5321cb7c89b4031d675c 250 SUPERFAMILY SSF55811 4 181 7.0E-16 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TSH58p_29495 622bd493bcbedcae04b0b98b961417ed 592 Gene3D G3DSA:1.25.40.10 74 151 5.8E-14 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29495 622bd493bcbedcae04b0b98b961417ed 592 SUPERFAMILY SSF48452 8 255 2.38E-27 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29495 622bd493bcbedcae04b0b98b961417ed 592 Pfam PF14559 Tetratricopeptide repeat 13 78 4.1E-6 T 14-10-2018 TSH58p_29495 622bd493bcbedcae04b0b98b961417ed 592 Gene3D G3DSA:1.25.40.10 159 274 2.3E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_29495 622bd493bcbedcae04b0b98b961417ed 592 SMART SM00028 69 102 0.0015 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29495 622bd493bcbedcae04b0b98b961417ed 592 SMART SM00028 35 68 83.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29495 622bd493bcbedcae04b0b98b961417ed 592 SMART SM00028 171 204 100.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29495 622bd493bcbedcae04b0b98b961417ed 592 SMART SM00028 103 136 17.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_29495 622bd493bcbedcae04b0b98b961417ed 592 Gene3D G3DSA:1.25.40.10 1 73 2.7E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_06760 d39d17aca5dc1d7ca54b307f8053b6dd 474 Gene3D G3DSA:3.30.465.10 121 459 5.6E-119 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TSH58p_06760 d39d17aca5dc1d7ca54b307f8053b6dd 474 Pfam PF08031 Berberine and berberine like 428 470 1.7E-13 T 14-10-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 TSH58p_06760 d39d17aca5dc1d7ca54b307f8053b6dd 474 Gene3D G3DSA:3.40.462.20 221 433 5.6E-119 T 14-10-2018 TSH58p_06760 d39d17aca5dc1d7ca54b307f8053b6dd 474 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 55 88 - T 14-10-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 TSH58p_06760 d39d17aca5dc1d7ca54b307f8053b6dd 474 SUPERFAMILY SSF56176 29 221 4.11E-57 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TSH58p_06760 d39d17aca5dc1d7ca54b307f8053b6dd 474 Gene3D G3DSA:3.30.43.10 30 108 1.2E-29 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 TSH58p_06760 d39d17aca5dc1d7ca54b307f8053b6dd 474 Pfam PF01565 FAD binding domain 56 189 7.9E-32 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TSH58p_01920 4e1d23578aee1e04540dc674db1b83ae 296 Pfam PF03547 Membrane transport protein 154 291 1.0E-14 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 TSH58p_01920 4e1d23578aee1e04540dc674db1b83ae 296 Pfam PF03547 Membrane transport protein 13 142 1.2E-6 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 TSH58p_08300 084f1f5b0e312162b82bd8e7b523aa6f 344 PIRSF PIRSF039012 1 338 1.7E-84 T 14-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 TSH58p_08300 084f1f5b0e312162b82bd8e7b523aa6f 344 Gene3D G3DSA:3.40.630.10 2 340 5.3E-93 T 14-10-2018 TSH58p_08300 084f1f5b0e312162b82bd8e7b523aa6f 344 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 46 332 7.4E-73 T 14-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 TSH58p_08300 084f1f5b0e312162b82bd8e7b523aa6f 344 SUPERFAMILY SSF53187 16 334 1.09E-53 T 14-10-2018 TSH58p_22370 46b5aae53744cfa275f7b159f5efdcf7 158 SUPERFAMILY SSF55961 22 155 1.83E-27 T 14-10-2018 TSH58p_22370 46b5aae53744cfa275f7b159f5efdcf7 158 Gene3D G3DSA:3.30.530.20 20 157 1.6E-36 T 14-10-2018 IPR023393 START-like domain superfamily TSH58p_22370 46b5aae53744cfa275f7b159f5efdcf7 158 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 21 155 2.3E-27 T 14-10-2018 IPR019587 Polyketide cyclase/dehydrase TSH58p_13115 8f675076e56060632b6b8ecbd789ba82 241 Gene3D G3DSA:3.40.50.1000 101 240 1.7E-24 T 14-10-2018 IPR023214 HAD superfamily TSH58p_13115 8f675076e56060632b6b8ecbd789ba82 241 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 93 205 5.5E-10 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSH58p_13115 8f675076e56060632b6b8ecbd789ba82 241 SUPERFAMILY SSF56784 27 234 7.97E-35 T 14-10-2018 IPR036412 HAD-like superfamily TSH58p_13115 8f675076e56060632b6b8ecbd789ba82 241 TIGRFAM TIGR01993 Pyr-5-nucltdase: pyrimidine 5'-nucleotidase 27 204 2.0E-57 T 14-10-2018 IPR010237 Pyrimidine 5-nucleotidase TSH58p_13115 8f675076e56060632b6b8ecbd789ba82 241 Pfam PF13419 Haloacid dehalogenase-like hydrolase 29 205 2.5E-11 T 14-10-2018 TSH58p_13115 8f675076e56060632b6b8ecbd789ba82 241 Gene3D G3DSA:1.10.150.450 24 100 2.4E-8 T 14-10-2018 TSH58p_07370 e00b38957cf36e6b539a73a3d9ed5a0b 221 SUPERFAMILY SSF46565 58 130 1.03E-9 T 14-10-2018 IPR036869 Chaperone J-domain superfamily TSH58p_07370 e00b38957cf36e6b539a73a3d9ed5a0b 221 Gene3D G3DSA:1.10.287.110 23 129 4.2E-19 T 14-10-2018 IPR036869 Chaperone J-domain superfamily TSH58p_30995 714cdd91580ab4989bba49a5e0162502 139 SUPERFAMILY SSF52172 6 129 1.57E-29 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_30995 714cdd91580ab4989bba49a5e0162502 139 SMART SM00448 8 124 5.1E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_30995 714cdd91580ab4989bba49a5e0162502 139 Pfam PF00072 Response regulator receiver domain 10 124 1.3E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_30995 714cdd91580ab4989bba49a5e0162502 139 Gene3D G3DSA:3.40.50.2300 3 133 2.5E-28 T 14-10-2018 TSH58p_23795 314cf58e18ca9661757f72e9313fa2ce 534 Pfam PF07690 Major Facilitator Superfamily 26 421 4.4E-27 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_23795 314cf58e18ca9661757f72e9313fa2ce 534 SUPERFAMILY SSF103473 21 516 3.14E-29 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_16745 45c4b8d8929295229cee7db09e27a2a2 558 SUPERFAMILY SSF52540 331 522 7.31E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_16745 45c4b8d8929295229cee7db09e27a2a2 558 Gene3D G3DSA:3.40.50.300 289 556 5.1E-70 T 14-10-2018 TSH58p_16745 45c4b8d8929295229cee7db09e27a2a2 558 Pfam PF00005 ABC transporter 24 193 3.7E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_16745 45c4b8d8929295229cee7db09e27a2a2 558 SUPERFAMILY SSF52540 10 246 3.65E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_16745 45c4b8d8929295229cee7db09e27a2a2 558 Pfam PF12848 ABC transporter 232 299 5.4E-13 T 14-10-2018 IPR032781 ABC-transporter extension domain TSH58p_16745 45c4b8d8929295229cee7db09e27a2a2 558 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 5 555 9.3E-298 T 14-10-2018 IPR022374 Energy-dependent translational throttle protein EttA GO:0045900 TSH58p_16745 45c4b8d8929295229cee7db09e27a2a2 558 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_16745 45c4b8d8929295229cee7db09e27a2a2 558 SMART SM00382 33 234 1.6E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_16745 45c4b8d8929295229cee7db09e27a2a2 558 SMART SM00382 350 526 8.2E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_16745 45c4b8d8929295229cee7db09e27a2a2 558 Gene3D G3DSA:3.40.50.300 4 287 8.0E-83 T 14-10-2018 TSH58p_16745 45c4b8d8929295229cee7db09e27a2a2 558 Pfam PF00005 ABC transporter 342 475 9.4E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_24415 fd11a92013662ed8518e28b0c3b8ce8c 211 Pfam PF05494 MlaC protein 45 201 4.3E-30 T 14-10-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC TSH58p_24415 fd11a92013662ed8518e28b0c3b8ce8c 211 Gene3D G3DSA:1.10.10.640 76 200 4.0E-22 T 14-10-2018 TSH58p_24415 fd11a92013662ed8518e28b0c3b8ce8c 211 Gene3D G3DSA:3.10.450.50 52 175 4.0E-22 T 14-10-2018 TSH58p_29550 6714712983cafb334a0b12085ca0ad4d 125 Pfam PF00072 Response regulator receiver domain 10 117 6.0E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_29550 6714712983cafb334a0b12085ca0ad4d 125 Gene3D G3DSA:3.40.50.2300 4 125 1.1E-27 T 14-10-2018 TSH58p_29550 6714712983cafb334a0b12085ca0ad4d 125 SMART SM00448 8 117 1.3E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_29550 6714712983cafb334a0b12085ca0ad4d 125 SUPERFAMILY SSF52172 7 122 8.25E-30 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_14845 c7f5096cdaf443623ffaccb0cf861197 340 Pfam PF09084 NMT1/THI5 like 47 257 5.6E-27 T 14-10-2018 IPR015168 SsuA/THI5-like TSH58p_14845 c7f5096cdaf443623ffaccb0cf861197 340 Gene3D G3DSA:3.40.190.10 160 339 5.8E-21 T 14-10-2018 TSH58p_14845 c7f5096cdaf443623ffaccb0cf861197 340 Gene3D G3DSA:3.40.190.10 35 159 1.0E-16 T 14-10-2018 TSH58p_14845 c7f5096cdaf443623ffaccb0cf861197 340 SUPERFAMILY SSF53850 38 256 1.63E-34 T 14-10-2018 TSH58p_25155 4c3bbe872d3fc412dba8e02ccfdccd42 316 Gene3D G3DSA:3.30.390.50 223 316 4.2E-25 T 14-10-2018 TSH58p_25155 4c3bbe872d3fc412dba8e02ccfdccd42 316 SMART SM01092 226 314 8.7E-21 T 14-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal TSH58p_25155 4c3bbe872d3fc412dba8e02ccfdccd42 316 SUPERFAMILY SSF56176 1 220 1.14E-59 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TSH58p_25155 4c3bbe872d3fc412dba8e02ccfdccd42 316 Gene3D G3DSA:3.30.465.10 1 222 1.5E-86 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TSH58p_25155 4c3bbe872d3fc412dba8e02ccfdccd42 316 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 227 275 1.6E-6 T 14-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal TSH58p_25155 4c3bbe872d3fc412dba8e02ccfdccd42 316 SUPERFAMILY SSF55447 224 314 5.36E-20 T 14-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily TSH58p_25155 4c3bbe872d3fc412dba8e02ccfdccd42 316 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 221 5.5E-52 T 14-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 TSH58p_21530 b9851b7f8b0cc8666659092c244e7c39 232 Gene3D G3DSA:3.40.50.1000 18 192 2.1E-47 T 14-10-2018 IPR023214 HAD superfamily TSH58p_21530 b9851b7f8b0cc8666659092c244e7c39 232 Pfam PF13419 Haloacid dehalogenase-like hydrolase 18 189 2.5E-28 T 14-10-2018 TSH58p_21530 b9851b7f8b0cc8666659092c244e7c39 232 Gene3D G3DSA:1.10.150.730 30 92 2.1E-47 T 14-10-2018 TSH58p_21530 b9851b7f8b0cc8666659092c244e7c39 232 SUPERFAMILY SSF56784 12 198 2.48E-41 T 14-10-2018 IPR036412 HAD-like superfamily TSH58p_31200 93cca4907ac9133b736132760e6639c1 357 Pfam PF13458 Periplasmic binding protein 16 353 6.6E-57 T 14-10-2018 IPR028081 Leucine-binding protein domain TSH58p_31200 93cca4907ac9133b736132760e6639c1 357 SUPERFAMILY SSF53822 15 355 3.7E-77 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_31200 93cca4907ac9133b736132760e6639c1 357 Gene3D G3DSA:3.40.50.2300 135 261 2.7E-70 T 14-10-2018 TSH58p_31200 93cca4907ac9133b736132760e6639c1 357 Gene3D G3DSA:3.40.50.2300 24 336 2.7E-70 T 14-10-2018 TSH58p_10925 a12b003034928266a77d9f395ccac0bb 151 PIRSF PIRSF029509 6 146 1.1E-37 T 14-10-2018 IPR016923 Uncharacterised conserved protein UCP029509, membrane TSH58p_16675 146cec81f6ab4fa9eb4bf1e4828299d7 172 Pfam PF00583 Acetyltransferase (GNAT) family 19 143 3.1E-9 T 14-10-2018 IPR000182 GNAT domain TSH58p_16675 146cec81f6ab4fa9eb4bf1e4828299d7 172 SUPERFAMILY SSF55729 6 146 1.24E-20 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_16675 146cec81f6ab4fa9eb4bf1e4828299d7 172 Gene3D G3DSA:3.40.630.30 2 149 1.2E-17 T 14-10-2018 TSH58p_07215 0d39300cc91164fc25e7964cf338469f 193 TIGRFAM TIGR02215 phage_chp_gp8: phage conserved hypothetical protein, phiE125 gp8 family 9 188 3.1E-26 T 14-10-2018 IPR011738 Phage conserved hypothetical protein TSH58p_07215 0d39300cc91164fc25e7964cf338469f 193 Pfam PF05135 Phage gp6-like head-tail connector protein 20 93 1.1E-5 T 14-10-2018 IPR021146 Phage gp6-like head-tail connector protein TSH58p_11360 216ea771c4e3e31ca6052175b10b41d0 533 Gene3D G3DSA:3.60.110.10 292 500 2.2E-13 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TSH58p_11360 216ea771c4e3e31ca6052175b10b41d0 533 SUPERFAMILY SSF56317 246 498 1.02E-37 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TSH58p_11360 216ea771c4e3e31ca6052175b10b41d0 533 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 25 519 20.714 T 14-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 TSH58p_11360 216ea771c4e3e31ca6052175b10b41d0 533 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 79 480 1.9E-91 T 14-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 TSH58p_11360 216ea771c4e3e31ca6052175b10b41d0 533 Pfam PF00795 Carbon-nitrogen hydrolase 251 498 1.1E-23 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 TSH58p_02210 7ea5e0d2abc8ad223c290e5098f6d89e 174 SUPERFAMILY SSF51316 1 142 4.08E-31 T 14-10-2018 IPR011057 Mss4-like superfamily TSH58p_02210 7ea5e0d2abc8ad223c290e5098f6d89e 174 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 26 108 1.4E-10 T 14-10-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 TSH58p_02210 7ea5e0d2abc8ad223c290e5098f6d89e 174 Gene3D G3DSA:2.170.150.70 3 123 6.4E-13 T 14-10-2018 TSH58p_11770 89bca0ba5d670fe3e66206119c0b668d 272 Gene3D G3DSA:3.40.50.300 12 254 2.3E-64 T 14-10-2018 TSH58p_11770 89bca0ba5d670fe3e66206119c0b668d 272 Pfam PF00005 ABC transporter 42 186 3.4E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_11770 89bca0ba5d670fe3e66206119c0b668d 272 SUPERFAMILY SSF52540 18 245 2.85E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_11770 89bca0ba5d670fe3e66206119c0b668d 272 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_11770 89bca0ba5d670fe3e66206119c0b668d 272 SMART SM00382 49 242 8.0E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_29440 332cc4330e4af885de343ff13ffa2463 124 SUPERFAMILY SSF52172 2 121 7.97E-27 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_29440 332cc4330e4af885de343ff13ffa2463 124 Pfam PF00072 Response regulator receiver domain 4 116 1.9E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_29440 332cc4330e4af885de343ff13ffa2463 124 Gene3D G3DSA:3.40.50.2300 2 124 5.1E-26 T 14-10-2018 TSH58p_29440 332cc4330e4af885de343ff13ffa2463 124 SMART SM00448 2 117 2.7E-16 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_02695 c63575d258298748fb82b38b528bf875 438 SUPERFAMILY SSF142764 13 435 7.59E-86 T 14-10-2018 TSH58p_02695 c63575d258298748fb82b38b528bf875 438 Gene3D G3DSA:3.40.980.20 266 437 1.4E-34 T 14-10-2018 TSH58p_02695 c63575d258298748fb82b38b528bf875 438 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 278 431 3.4E-29 T 14-10-2018 IPR031475 Four-carbon acid sugar kinase, C-terminal domain TSH58p_02695 c63575d258298748fb82b38b528bf875 438 Pfam PF07005 Putative sugar-binding N-terminal domain 13 254 3.2E-48 T 14-10-2018 IPR010737 Four-carbon acid sugar kinase, N-terminal domain TSH58p_02695 c63575d258298748fb82b38b528bf875 438 Gene3D G3DSA:3.40.50.10840 10 265 1.3E-65 T 14-10-2018 IPR037051 Four-carbon acid sugar kinase, N-terminal domain superfamily TSH58p_02575 42828d165c1bfc809b47e1f70ecfc1ac 395 Gene3D G3DSA:1.10.287.90 22 106 3.4E-30 T 14-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_02575 42828d165c1bfc809b47e1f70ecfc1ac 395 SUPERFAMILY SSF49503 123 282 1.12E-48 T 14-10-2018 IPR008972 Cupredoxin TSH58p_02575 42828d165c1bfc809b47e1f70ecfc1ac 395 SUPERFAMILY SSF81464 13 111 3.11E-21 T 14-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_02575 42828d165c1bfc809b47e1f70ecfc1ac 395 Pfam PF06481 COX Aromatic Rich Motif 241 286 4.4E-19 T 14-10-2018 IPR010514 COX aromatic rich motif GO:0008827|GO:0016021|GO:0022900|GO:0055114 TSH58p_02575 42828d165c1bfc809b47e1f70ecfc1ac 395 TIGRFAM TIGR01433 CyoA: ubiquinol oxidase, subunit II 8 241 2.3E-103 T 14-10-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 TSH58p_02575 42828d165c1bfc809b47e1f70ecfc1ac 395 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 152 222 1.1E-6 T 14-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_02575 42828d165c1bfc809b47e1f70ecfc1ac 395 Gene3D G3DSA:2.60.40.420 107 283 1.4E-49 T 14-10-2018 IPR008972 Cupredoxin TSH58p_11745 23df76cc7fc4fc5f7677a6d98b2a57c1 478 Gene3D G3DSA:3.40.50.300 135 316 2.1E-64 T 14-10-2018 TSH58p_11745 23df76cc7fc4fc5f7677a6d98b2a57c1 478 Gene3D G3DSA:1.10.8.60 317 393 5.3E-22 T 14-10-2018 TSH58p_11745 23df76cc7fc4fc5f7677a6d98b2a57c1 478 Pfam PF00158 Sigma-54 interaction domain 146 312 2.8E-66 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 TSH58p_11745 23df76cc7fc4fc5f7677a6d98b2a57c1 478 SMART SM00448 6 117 2.2E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_11745 23df76cc7fc4fc5f7677a6d98b2a57c1 478 Gene3D G3DSA:1.10.10.60 427 468 1.9E-11 T 14-10-2018 TSH58p_11745 23df76cc7fc4fc5f7677a6d98b2a57c1 478 SUPERFAMILY SSF52540 145 387 4.81E-72 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_11745 23df76cc7fc4fc5f7677a6d98b2a57c1 478 Pfam PF02954 Bacterial regulatory protein, Fis family 432 469 5.4E-11 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TSH58p_11745 23df76cc7fc4fc5f7677a6d98b2a57c1 478 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 231 246 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 TSH58p_11745 23df76cc7fc4fc5f7677a6d98b2a57c1 478 SUPERFAMILY SSF46689 358 468 2.24E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_11745 23df76cc7fc4fc5f7677a6d98b2a57c1 478 SMART SM00382 165 308 2.4E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_11745 23df76cc7fc4fc5f7677a6d98b2a57c1 478 Pfam PF00072 Response regulator receiver domain 8 117 1.7E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_11745 23df76cc7fc4fc5f7677a6d98b2a57c1 478 Gene3D G3DSA:3.40.50.2300 4 134 7.2E-32 T 14-10-2018 TSH58p_11745 23df76cc7fc4fc5f7677a6d98b2a57c1 478 SUPERFAMILY SSF52172 5 189 1.17E-40 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_20120 ca4dd247a72ca4e6448e14f0f5f8db99 242 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 14-10-2018 IPR019776 Flagellar basal body rod protein, conserved site TSH58p_20120 ca4dd247a72ca4e6448e14f0f5f8db99 242 Pfam PF00460 Flagella basal body rod protein 5 35 7.2E-11 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 TSH58p_20120 ca4dd247a72ca4e6448e14f0f5f8db99 242 SUPERFAMILY SSF117143 79 199 1.57E-20 T 14-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like TSH58p_20120 ca4dd247a72ca4e6448e14f0f5f8db99 242 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 5 122 1.3E-40 T 14-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G TSH58p_20120 ca4dd247a72ca4e6448e14f0f5f8db99 242 TIGRFAM TIGR02490 flgF: flagellar basal-body rod protein FlgF 5 218 1.6E-60 T 14-10-2018 IPR012836 Flagellar basal-body rod FlgF GO:0030694|GO:0071973 TSH58p_20120 ca4dd247a72ca4e6448e14f0f5f8db99 242 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 166 236 2.3E-15 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain TSH58p_22390 4231b0cda17fe1364ade7fecc9a58567 290 SUPERFAMILY SSF48576 24 286 1.22E-49 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily TSH58p_22390 4231b0cda17fe1364ade7fecc9a58567 290 Pfam PF00494 Squalene/phytoene synthase 22 269 1.2E-44 T 14-10-2018 TSH58p_22390 4231b0cda17fe1364ade7fecc9a58567 290 Gene3D G3DSA:1.10.600.10 17 263 2.9E-54 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily TSH58p_12930 a4e974261fc458f8ab86a759185eae8c 422 Pfam PF00999 Sodium/hydrogen exchanger family 17 406 3.0E-47 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TSH58p_12930 a4e974261fc458f8ab86a759185eae8c 422 Gene3D G3DSA:1.20.1530.20 8 413 3.9E-70 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily TSH58p_12645 cf497df902fd6761914bf3bd1d3edbb4 636 Gene3D G3DSA:3.40.50.1110 420 628 2.6E-5 T 14-10-2018 IPR036514 SGNH hydrolase superfamily TSH58p_12645 cf497df902fd6761914bf3bd1d3edbb4 636 Pfam PF01757 Acyltransferase family 5 327 2.1E-26 T 14-10-2018 IPR002656 Acyltransferase 3 GO:0016747 TSH58p_12645 cf497df902fd6761914bf3bd1d3edbb4 636 SUPERFAMILY SSF52266 405 627 5.68E-6 T 14-10-2018 TSH58p_10990 588b54706eedecd5bd37ab8f46d5a67f 340 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 21 333 1.5E-51 T 14-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 TSH58p_10990 588b54706eedecd5bd37ab8f46d5a67f 340 Gene3D G3DSA:3.40.50.300 19 134 1.8E-8 T 14-10-2018 TSH58p_10990 588b54706eedecd5bd37ab8f46d5a67f 340 Gene3D G3DSA:1.10.8.60 143 212 1.6E-7 T 14-10-2018 TSH58p_10990 588b54706eedecd5bd37ab8f46d5a67f 340 SUPERFAMILY SSF48019 221 335 4.93E-18 T 14-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 TSH58p_10990 588b54706eedecd5bd37ab8f46d5a67f 340 SUPERFAMILY SSF52540 14 210 1.59E-10 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_10990 588b54706eedecd5bd37ab8f46d5a67f 340 Gene3D G3DSA:1.20.272.10 219 338 1.6E-14 T 14-10-2018 TSH58p_24465 2b37ffb01b02a50b03fc2e434f984fda 94 Gene3D G3DSA:3.40.630.30 7 94 4.2E-18 T 14-10-2018 TSH58p_24465 2b37ffb01b02a50b03fc2e434f984fda 94 SUPERFAMILY SSF55729 6 93 1.8E-22 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_24465 2b37ffb01b02a50b03fc2e434f984fda 94 Pfam PF14542 GCN5-related N-acetyl-transferase 15 91 2.2E-19 T 14-10-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase TSH58p_11210 c399e6f4f167427771fcab7b8402dc5f 199 Pfam PF01810 LysE type translocator 13 198 1.7E-35 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 TSH58p_21860 73a1a77757abf1f8272e276afd00dba5 879 Gene3D G3DSA:1.20.1530.20 6 418 1.1E-8 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily TSH58p_21860 73a1a77757abf1f8272e276afd00dba5 879 SUPERFAMILY SSF51206 699 819 6.28E-31 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like TSH58p_21860 73a1a77757abf1f8272e276afd00dba5 879 Gene3D G3DSA:2.60.120.10 695 821 8.6E-35 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_21860 73a1a77757abf1f8272e276afd00dba5 879 Pfam PF00999 Sodium/hydrogen exchanger family 13 416 6.1E-56 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TSH58p_21860 73a1a77757abf1f8272e276afd00dba5 879 Pfam PF00027 Cyclic nucleotide-binding domain 729 810 2.3E-18 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_21860 73a1a77757abf1f8272e276afd00dba5 879 SMART SM00100 708 825 6.3E-18 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain TSH58p_21860 73a1a77757abf1f8272e276afd00dba5 879 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 735 751 - T 14-10-2018 IPR018488 Cyclic nucleotide-binding, conserved site TSH58p_12100 aff3f252996d3d065c1b00ea007b842b 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 222 6.6E-21 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_12100 aff3f252996d3d065c1b00ea007b842b 229 SUPERFAMILY SSF161098 11 207 2.62E-39 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_12100 aff3f252996d3d065c1b00ea007b842b 229 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 116 8.1E-23 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 TSH58p_12100 aff3f252996d3d065c1b00ea007b842b 229 Gene3D G3DSA:1.10.3720.10 1 222 5.3E-50 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_21405 1658adadb0c7bf2a2c07fd1a15f9021f 281 Gene3D G3DSA:3.40.50.150 39 249 1.2E-30 T 14-10-2018 TSH58p_21405 1658adadb0c7bf2a2c07fd1a15f9021f 281 Pfam PF13649 Methyltransferase domain 55 151 1.5E-12 T 14-10-2018 TSH58p_21405 1658adadb0c7bf2a2c07fd1a15f9021f 281 SUPERFAMILY SSF53335 28 248 2.05E-31 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_18525 1658adadb0c7bf2a2c07fd1a15f9021f 281 Gene3D G3DSA:3.40.50.150 39 249 1.2E-30 T 14-10-2018 TSH58p_18525 1658adadb0c7bf2a2c07fd1a15f9021f 281 Pfam PF13649 Methyltransferase domain 55 151 1.5E-12 T 14-10-2018 TSH58p_18525 1658adadb0c7bf2a2c07fd1a15f9021f 281 SUPERFAMILY SSF53335 28 248 2.05E-31 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_06825 4eb8bc2e5383b1f89db3f778755c8774 160 Pfam PF04073 Aminoacyl-tRNA editing domain 30 147 8.1E-30 T 14-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 TSH58p_06825 4eb8bc2e5383b1f89db3f778755c8774 160 Gene3D G3DSA:3.90.960.10 3 159 5.5E-47 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 TSH58p_06825 4eb8bc2e5383b1f89db3f778755c8774 160 SUPERFAMILY SSF55826 9 154 2.49E-38 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 TSH58p_08905 57ed87cdfb1a519482c6409a763a627c 192 Pfam PF09335 SNARE associated Golgi protein 38 155 7.9E-10 T 14-10-2018 IPR032816 SNARE associated Golgi protein TSH58p_08355 8b8a468ff53952cdd29d7b666a1d0d83 257 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 244 7.9E-24 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_08355 8b8a468ff53952cdd29d7b666a1d0d83 257 Gene3D G3DSA:1.10.3720.10 47 245 1.3E-23 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_08355 8b8a468ff53952cdd29d7b666a1d0d83 257 SUPERFAMILY SSF161098 52 233 3.14E-27 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_16785 970cbc3b7ef24c32acfd18bd0d7f9b3d 164 Gene3D G3DSA:3.10.129.10 5 142 5.8E-41 T 14-10-2018 TSH58p_16785 970cbc3b7ef24c32acfd18bd0d7f9b3d 164 SUPERFAMILY SSF54637 7 159 2.06E-45 T 14-10-2018 IPR029069 HotDog domain superfamily TSH58p_16785 970cbc3b7ef24c32acfd18bd0d7f9b3d 164 Pfam PF13279 Thioesterase-like superfamily 15 131 9.2E-20 T 14-10-2018 TSH58p_26315 069cbc2c4be924adb6103aa84f65d56a 267 Pfam PF10615 Protein of unknown function (DUF2470) 161 237 2.3E-14 T 14-10-2018 IPR019595 Domain of unknown function DUF2470 TSH58p_26315 069cbc2c4be924adb6103aa84f65d56a 267 SUPERFAMILY SSF50475 27 246 1.47E-44 T 14-10-2018 TSH58p_26315 069cbc2c4be924adb6103aa84f65d56a 267 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 28 96 1.2E-6 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 TSH58p_26315 069cbc2c4be924adb6103aa84f65d56a 267 Gene3D G3DSA:2.30.110.10 1 147 6.0E-33 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TSH58p_26315 069cbc2c4be924adb6103aa84f65d56a 267 Gene3D G3DSA:3.20.180.10 151 244 5.9E-26 T 14-10-2018 IPR037119 Haem oxygenase HugZ-like superfamily TSH58p_25555 cba750068d5554228d844853dc907caf 470 SUPERFAMILY SSF53850 43 306 2.25E-21 T 14-10-2018 TSH58p_25555 cba750068d5554228d844853dc907caf 470 Gene3D G3DSA:3.40.190.10 46 440 7.2E-140 T 14-10-2018 TSH58p_25555 cba750068d5554228d844853dc907caf 470 Gene3D G3DSA:3.40.190.10 131 445 7.2E-140 T 14-10-2018 TSH58p_25555 cba750068d5554228d844853dc907caf 470 Pfam PF13379 NMT1-like family 42 318 2.2E-103 T 14-10-2018 TSH58p_09675 690dbf5d4102c020e24519c9cab1a574 101 SUPERFAMILY SSF52091 1 99 2.55E-18 T 14-10-2018 IPR036513 STAS domain superfamily TSH58p_09675 690dbf5d4102c020e24519c9cab1a574 101 Pfam PF13466 STAS domain 16 93 4.5E-10 T 14-10-2018 IPR002645 STAS domain TSH58p_09675 690dbf5d4102c020e24519c9cab1a574 101 Gene3D G3DSA:3.30.750.24 1 101 4.3E-17 T 14-10-2018 IPR036513 STAS domain superfamily TSH58p_14855 a7c53b53eed78a431b6bd8cd1d83aa6f 257 Pfam PF00005 ABC transporter 18 157 5.6E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_14855 a7c53b53eed78a431b6bd8cd1d83aa6f 257 SMART SM00382 27 208 2.3E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_14855 a7c53b53eed78a431b6bd8cd1d83aa6f 257 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_14855 a7c53b53eed78a431b6bd8cd1d83aa6f 257 Gene3D G3DSA:3.40.50.300 3 253 7.0E-63 T 14-10-2018 TSH58p_14855 a7c53b53eed78a431b6bd8cd1d83aa6f 257 SUPERFAMILY SSF52540 3 219 2.06E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_23465 0c2f7bb620ecf9bf06b18af994bd7c05 68 Gene3D G3DSA:3.90.820.10 3 68 3.4E-29 T 14-10-2018 TSH58p_23465 0c2f7bb620ecf9bf06b18af994bd7c05 68 SMART SM00923 8 58 2.2E-26 T 14-10-2018 IPR005153 MbtH-like domain TSH58p_23465 0c2f7bb620ecf9bf06b18af994bd7c05 68 SUPERFAMILY SSF160582 7 66 3.66E-24 T 14-10-2018 IPR038020 MbtH-like domain superfamily TSH58p_23465 0c2f7bb620ecf9bf06b18af994bd7c05 68 Pfam PF03621 MbtH-like protein 8 57 4.8E-25 T 14-10-2018 IPR005153 MbtH-like domain TSH58p_30730 f5c570933b0a015dfd717abf99669706 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 288 9.9E-27 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_30730 f5c570933b0a015dfd717abf99669706 290 Gene3D G3DSA:1.10.3720.10 72 285 1.6E-23 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_30730 f5c570933b0a015dfd717abf99669706 290 SUPERFAMILY SSF161098 79 272 4.45E-25 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_30730 f5c570933b0a015dfd717abf99669706 290 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 5 54 4.9E-9 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TSH58p_29855 9c9ad9f5feaafd419cbefc1b380b4e3e 254 SUPERFAMILY SSF53335 84 175 2.37E-10 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_29855 9c9ad9f5feaafd419cbefc1b380b4e3e 254 Gene3D G3DSA:3.40.50.150 67 175 1.2E-8 T 14-10-2018 TSH58p_02740 46db596f1debe275b522c5fed355d361 353 Pfam PF00850 Histone deacetylase domain 27 340 2.8E-69 T 14-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSH58p_02740 46db596f1debe275b522c5fed355d361 353 SUPERFAMILY SSF52768 3 346 7.67E-90 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily TSH58p_02740 46db596f1debe275b522c5fed355d361 353 PRINTS PR01270 Histone deacetylase superfamily signature 279 289 1.7E-8 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSH58p_02740 46db596f1debe275b522c5fed355d361 353 PRINTS PR01270 Histone deacetylase superfamily signature 155 178 1.7E-8 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSH58p_02740 46db596f1debe275b522c5fed355d361 353 Gene3D G3DSA:3.40.800.20 1 347 9.7E-119 T 14-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSH58p_03605 2ee3a577cf26b0ecab430652af6e46cc 971 SUPERFAMILY SSF49899 589 728 2.18E-8 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily TSH58p_03605 2ee3a577cf26b0ecab430652af6e46cc 971 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 603 730 2.8E-7 T 14-10-2018 TSH58p_03605 2ee3a577cf26b0ecab430652af6e46cc 971 Gene3D G3DSA:2.60.120.200 553 747 8.5E-8 T 14-10-2018 TSH58p_02585 f33073830f9e505acd1ce6a8a5373bdb 211 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 31 210 9.9E-82 T 14-10-2018 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 TSH58p_02585 f33073830f9e505acd1ce6a8a5373bdb 211 Gene3D G3DSA:1.20.120.80 25 210 2.9E-57 T 14-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_02585 f33073830f9e505acd1ce6a8a5373bdb 211 SUPERFAMILY SSF81452 18 208 1.2E-59 T 14-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_02585 f33073830f9e505acd1ce6a8a5373bdb 211 Pfam PF00510 Cytochrome c oxidase subunit III 28 208 4.3E-14 T 14-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSH58p_07840 01f88307a0d85079661cec4b9047882f 400 SUPERFAMILY SSF53383 4 399 7.4E-84 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_07840 01f88307a0d85079661cec4b9047882f 400 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 214 234 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site TSH58p_07840 01f88307a0d85079661cec4b9047882f 400 Gene3D G3DSA:3.40.640.10 30 297 1.9E-107 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_07840 01f88307a0d85079661cec4b9047882f 400 Gene3D G3DSA:3.90.1150.10 15 394 1.9E-107 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_07840 01f88307a0d85079661cec4b9047882f 400 Pfam PF00266 Aminotransferase class-V 21 393 8.5E-63 T 14-10-2018 IPR000192 Aminotransferase class V domain TSH58p_26720 c9dcec92af97ea20836475c716ec729e 527 Pfam PF03929 PepSY-associated TM region 4 361 6.1E-64 T 14-10-2018 IPR005625 PepSY-associated TM protein TSH58p_14060 9a3a23655dd0e3ee5eaefebcab7eace0 350 PRINTS PR00721 Stomatin signature 118 135 3.5E-29 T 14-10-2018 IPR001972 Stomatin family GO:0016020 TSH58p_14060 9a3a23655dd0e3ee5eaefebcab7eace0 350 PRINTS PR00721 Stomatin signature 138 161 3.5E-29 T 14-10-2018 IPR001972 Stomatin family GO:0016020 TSH58p_14060 9a3a23655dd0e3ee5eaefebcab7eace0 350 PRINTS PR00721 Stomatin signature 162 180 3.5E-29 T 14-10-2018 IPR001972 Stomatin family GO:0016020 TSH58p_14060 9a3a23655dd0e3ee5eaefebcab7eace0 350 PRINTS PR00721 Stomatin signature 181 202 3.5E-29 T 14-10-2018 IPR001972 Stomatin family GO:0016020 TSH58p_14060 9a3a23655dd0e3ee5eaefebcab7eace0 350 PRINTS PR00721 Stomatin signature 83 104 3.5E-29 T 14-10-2018 IPR001972 Stomatin family GO:0016020 TSH58p_14060 9a3a23655dd0e3ee5eaefebcab7eace0 350 Gene3D G3DSA:3.30.479.30 56 188 2.3E-39 T 14-10-2018 TSH58p_14060 9a3a23655dd0e3ee5eaefebcab7eace0 350 Pfam PF01145 SPFH domain / Band 7 family 32 202 1.1E-31 T 14-10-2018 IPR001107 Band 7 domain TSH58p_14060 9a3a23655dd0e3ee5eaefebcab7eace0 350 ProSitePatterns PS01270 Band 7 protein family signature. 142 170 - T 14-10-2018 IPR018080 Band 7/stomatin-like, conserved site TSH58p_14060 9a3a23655dd0e3ee5eaefebcab7eace0 350 SUPERFAMILY SSF117892 59 193 1.07E-40 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily TSH58p_14060 9a3a23655dd0e3ee5eaefebcab7eace0 350 SMART SM00244 28 186 3.2E-55 T 14-10-2018 IPR001107 Band 7 domain TSH58p_06465 308dec40494d3d253beb452e1ca75a6d 223 Pfam PF01810 LysE type translocator 22 207 1.8E-19 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 TSH58p_12040 4248eb35133b82a5c385962f16c4797e 144 Gene3D G3DSA:3.10.180.10 2 144 2.1E-59 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSH58p_12040 4248eb35133b82a5c385962f16c4797e 144 SUPERFAMILY SSF54593 4 132 2.34E-31 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSH58p_12040 4248eb35133b82a5c385962f16c4797e 144 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 126 1.4E-11 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TSH58p_09635 4442d49b7faefde383cbb752bfdec326 245 Gene3D G3DSA:3.30.565.10 80 245 1.3E-17 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_09635 4442d49b7faefde383cbb752bfdec326 245 SUPERFAMILY SSF55874 113 244 1.03E-7 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_09635 4442d49b7faefde383cbb752bfdec326 245 Pfam PF13581 Histidine kinase-like ATPase domain 107 242 8.4E-13 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_02155 418d398112c1d025acc70ea757cac7c8 172 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 20 148 3.5E-29 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ TSH58p_15395 ec7341f3852c2338f589c7594fa1615c 256 Hamap MF_00415 Flagellar L-ring protein [flgH]. 12 254 24.506 T 14-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 TSH58p_15395 ec7341f3852c2338f589c7594fa1615c 256 PRINTS PR01008 Flagellar L-ring protein signature 217 231 2.5E-27 T 14-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 TSH58p_15395 ec7341f3852c2338f589c7594fa1615c 256 PRINTS PR01008 Flagellar L-ring protein signature 233 247 2.5E-27 T 14-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 TSH58p_15395 ec7341f3852c2338f589c7594fa1615c 256 PRINTS PR01008 Flagellar L-ring protein signature 170 185 2.5E-27 T 14-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 TSH58p_15395 ec7341f3852c2338f589c7594fa1615c 256 PRINTS PR01008 Flagellar L-ring protein signature 196 212 2.5E-27 T 14-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 TSH58p_15395 ec7341f3852c2338f589c7594fa1615c 256 PRINTS PR01008 Flagellar L-ring protein signature 90 102 2.5E-27 T 14-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 TSH58p_15395 ec7341f3852c2338f589c7594fa1615c 256 Pfam PF02107 Flagellar L-ring protein 69 255 2.7E-57 T 14-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 TSH58p_25900 7e59909729aa51bdd8161b613732ba1e 411 Pfam PF00696 Amino acid kinase family 3 229 1.2E-51 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TSH58p_25900 7e59909729aa51bdd8161b613732ba1e 411 Pfam PF13840 ACT domain 341 403 4.6E-15 T 14-10-2018 IPR027795 CASTOR, ACT domain TSH58p_25900 7e59909729aa51bdd8161b613732ba1e 411 SUPERFAMILY SSF55021 253 332 4.58E-21 T 14-10-2018 TSH58p_25900 7e59909729aa51bdd8161b613732ba1e 411 SUPERFAMILY SSF53633 3 248 3.8E-73 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSH58p_25900 7e59909729aa51bdd8161b613732ba1e 411 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 14-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TSH58p_25900 7e59909729aa51bdd8161b613732ba1e 411 Gene3D G3DSA:3.30.70.260 265 343 5.6E-57 T 14-10-2018 TSH58p_25900 7e59909729aa51bdd8161b613732ba1e 411 PIRSF PIRSF000726 59 411 2.1E-127 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TSH58p_25900 7e59909729aa51bdd8161b613732ba1e 411 PIRSF PIRSF000726 1 63 1.1E-19 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TSH58p_25900 7e59909729aa51bdd8161b613732ba1e 411 Gene3D G3DSA:3.30.70.260 261 408 5.6E-57 T 14-10-2018 TSH58p_25900 7e59909729aa51bdd8161b613732ba1e 411 Pfam PF01842 ACT domain 270 329 2.2E-13 T 14-10-2018 IPR002912 ACT domain TSH58p_25900 7e59909729aa51bdd8161b613732ba1e 411 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 4 407 5.0E-129 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TSH58p_25900 7e59909729aa51bdd8161b613732ba1e 411 Gene3D G3DSA:3.40.1160.10 1 260 1.2E-85 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSH58p_25900 7e59909729aa51bdd8161b613732ba1e 411 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 59 406 1.9E-114 T 14-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TSH58p_25900 7e59909729aa51bdd8161b613732ba1e 411 SUPERFAMILY SSF55021 335 409 5.27E-22 T 14-10-2018 TSH58p_30585 d2d9263300e18c5755ab7fff173a6d52 490 SUPERFAMILY SSF51905 6 255 8.42E-16 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_30585 d2d9263300e18c5755ab7fff173a6d52 490 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 186 7.6E-5 T 14-10-2018 TSH58p_30585 d2d9263300e18c5755ab7fff173a6d52 490 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 7.6E-5 T 14-10-2018 TSH58p_30585 d2d9263300e18c5755ab7fff173a6d52 490 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 213 231 7.6E-5 T 14-10-2018 TSH58p_30585 d2d9263300e18c5755ab7fff173a6d52 490 Pfam PF13454 FAD-NAD(P)-binding 10 177 1.4E-27 T 14-10-2018 IPR038732 FAD-dependent urate hydroxylase HpyO, FAD/NAD(P)-binding domain TSH58p_12270 5717327a71d55de1f9d6bf84d391cf24 453 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 16 333 3.0E-55 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSH58p_12270 5717327a71d55de1f9d6bf84d391cf24 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 5.4E-12 T 14-10-2018 TSH58p_12270 5717327a71d55de1f9d6bf84d391cf24 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 290 312 5.4E-12 T 14-10-2018 TSH58p_12270 5717327a71d55de1f9d6bf84d391cf24 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 109 127 5.4E-12 T 14-10-2018 TSH58p_12270 5717327a71d55de1f9d6bf84d391cf24 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 17 36 5.4E-12 T 14-10-2018 TSH58p_12270 5717327a71d55de1f9d6bf84d391cf24 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 194 1.2E-8 T 14-10-2018 TSH58p_12270 5717327a71d55de1f9d6bf84d391cf24 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 305 312 1.2E-8 T 14-10-2018 TSH58p_12270 5717327a71d55de1f9d6bf84d391cf24 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 16 38 1.2E-8 T 14-10-2018 TSH58p_12270 5717327a71d55de1f9d6bf84d391cf24 453 SUPERFAMILY SSF51905 11 228 8.19E-35 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_12270 5717327a71d55de1f9d6bf84d391cf24 453 Gene3D G3DSA:3.50.50.100 13 414 6.4E-119 T 14-10-2018 TSH58p_12270 5717327a71d55de1f9d6bf84d391cf24 453 SUPERFAMILY SSF51905 163 338 3.77E-22 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_02080 9183f34ecba322e55e1f2c4cd9793c05 149 Gene3D G3DSA:2.20.28.140 2 39 2.5E-11 T 14-10-2018 TSH58p_02080 9183f34ecba322e55e1f2c4cd9793c05 149 PIRSF PIRSF000077 41 146 1.2E-31 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 TSH58p_02080 9183f34ecba322e55e1f2c4cd9793c05 149 ProSitePatterns PS00194 Thioredoxin family active site. 63 81 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 TSH58p_02080 9183f34ecba322e55e1f2c4cd9793c05 149 Pfam PF00085 Thioredoxin 45 143 1.2E-26 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 TSH58p_02080 9183f34ecba322e55e1f2c4cd9793c05 149 PRINTS PR00421 Thioredoxin family signature 62 70 2.1E-7 T 14-10-2018 TSH58p_02080 9183f34ecba322e55e1f2c4cd9793c05 149 PRINTS PR00421 Thioredoxin family signature 70 79 2.1E-7 T 14-10-2018 TSH58p_02080 9183f34ecba322e55e1f2c4cd9793c05 149 PRINTS PR00421 Thioredoxin family signature 110 121 2.1E-7 T 14-10-2018 TSH58p_02080 9183f34ecba322e55e1f2c4cd9793c05 149 SUPERFAMILY SSF52833 31 146 2.7E-35 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_02080 9183f34ecba322e55e1f2c4cd9793c05 149 TIGRFAM TIGR01068 thioredoxin: thioredoxin 47 144 3.0E-32 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 TSH58p_02080 9183f34ecba322e55e1f2c4cd9793c05 149 Gene3D G3DSA:3.40.30.10 40 149 1.3E-29 T 14-10-2018 TSH58p_22715 f7f82d955cd594a158ee29d78cbee777 505 TIGRFAM TIGR01539 portal_lambda: phage portal protein, lambda family 22 480 2.3E-100 T 14-10-2018 IPR006429 Phage portal protein, lambda family GO:0005198|GO:0019068 TSH58p_22715 f7f82d955cd594a158ee29d78cbee777 505 Pfam PF05136 Phage portal protein, lambda family 21 379 1.3E-116 T 14-10-2018 IPR006429 Phage portal protein, lambda family GO:0005198|GO:0019068 TSH58p_06675 8b675c0340d30833c3f1bb00c0c52fe7 193 SUPERFAMILY SSF161111 2 175 1.83E-17 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TSH58p_22710 82d0b5e7c666d93df1c6108e109e922d 281 Pfam PF01343 Peptidase family S49 123 273 1.4E-26 T 14-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 TSH58p_22710 82d0b5e7c666d93df1c6108e109e922d 281 Gene3D G3DSA:3.90.226.10 55 274 1.0E-39 T 14-10-2018 TSH58p_22710 82d0b5e7c666d93df1c6108e109e922d 281 Gene3D G3DSA:3.40.1750.20 163 229 1.0E-39 T 14-10-2018 TSH58p_22710 82d0b5e7c666d93df1c6108e109e922d 281 SUPERFAMILY SSF52096 46 266 1.49E-24 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_04455 bebadfd17953f61cbeadb5ec40cd2aa3 72 SUPERFAMILY SSF47413 2 47 2.45E-7 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_04455 bebadfd17953f61cbeadb5ec40cd2aa3 72 Pfam PF01381 Helix-turn-helix 2 45 1.8E-7 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_04455 bebadfd17953f61cbeadb5ec40cd2aa3 72 Gene3D G3DSA:1.10.260.40 1 69 1.6E-16 T 14-10-2018 TSH58p_01040 404b87cd5ddcc1c4f51c6358d985e8a9 169 Gene3D G3DSA:3.10.129.10 17 152 3.7E-36 T 14-10-2018 TSH58p_01040 404b87cd5ddcc1c4f51c6358d985e8a9 169 Pfam PF13279 Thioesterase-like superfamily 27 144 5.7E-21 T 14-10-2018 TSH58p_01040 404b87cd5ddcc1c4f51c6358d985e8a9 169 SUPERFAMILY SSF54637 22 165 1.62E-40 T 14-10-2018 IPR029069 HotDog domain superfamily TSH58p_30270 6e84f926b8c8c6dd5c9cd3a9954f9466 658 Gene3D G3DSA:1.10.3470.10 335 654 1.4E-69 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_30270 6e84f926b8c8c6dd5c9cd3a9954f9466 658 SUPERFAMILY SSF81345 13 320 1.44E-51 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_30270 6e84f926b8c8c6dd5c9cd3a9954f9466 658 SUPERFAMILY SSF81345 341 652 1.44E-60 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_30270 6e84f926b8c8c6dd5c9cd3a9954f9466 658 Gene3D G3DSA:1.10.3470.10 3 324 9.3E-65 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_30270 6e84f926b8c8c6dd5c9cd3a9954f9466 658 Pfam PF01032 FecCD transport family 379 651 9.7E-69 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TSH58p_30270 6e84f926b8c8c6dd5c9cd3a9954f9466 658 Pfam PF01032 FecCD transport family 44 318 1.7E-58 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TSH58p_03735 bb61bc7c2139ca5d1b8da615646bda17 394 Pfam PF02371 Transposase IS116/IS110/IS902 family 205 290 6.2E-27 T 14-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 TSH58p_03735 bb61bc7c2139ca5d1b8da615646bda17 394 Pfam PF01548 Transposase 2 140 1.6E-9 T 14-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 TSH58p_23710 55cd3c5c1e402652f9c1f10b617338ee 637 Pfam PF06537 Di-haem oxidoreductase, putative peroxidase 518 582 1.8E-9 T 14-10-2018 IPR010538 Di-haem oxidoreductase, putative peroxidase TSH58p_23710 55cd3c5c1e402652f9c1f10b617338ee 637 SUPERFAMILY SSF46626 301 625 1.24E-13 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_23370 a3626836f7f0b3b4c37cb2c2a6625804 157 SUPERFAMILY SSF160719 38 143 2.48E-10 T 14-10-2018 TSH58p_23370 a3626836f7f0b3b4c37cb2c2a6625804 157 Pfam PF04965 Gene 25-like lysozyme 40 131 1.3E-14 T 14-10-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD TSH58p_23370 a3626836f7f0b3b4c37cb2c2a6625804 157 TIGRFAM TIGR03357 VI_zyme: type VI secretion system lysozyme-like protein 14 146 1.3E-25 T 14-10-2018 IPR017737 Type VI secretion system, lysozyme-related protein TSH58p_07600 3efb79a300a015618667f4ccd8e13d67 292 Pfam PF13289 SIR2-like domain 116 272 2.5E-19 T 14-10-2018 IPR039444 SIR2-like domain TSH58p_01885 3efca1ed6a16f02ef976eb8efdd5f897 294 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 36 178 2.7E-32 T 14-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 TSH58p_01885 3efca1ed6a16f02ef976eb8efdd5f897 294 SUPERFAMILY SSF109709 117 214 1.7E-17 T 14-10-2018 TSH58p_01885 3efca1ed6a16f02ef976eb8efdd5f897 294 Gene3D G3DSA:1.10.10.2830 113 222 2.3E-17 T 14-10-2018 TSH58p_01885 3efca1ed6a16f02ef976eb8efdd5f897 294 SMART SM00470 37 124 5.7E-20 T 14-10-2018 IPR003115 ParB/Sulfiredoxin TSH58p_01885 3efca1ed6a16f02ef976eb8efdd5f897 294 Gene3D G3DSA:3.90.1530.30 50 111 1.5E-17 T 14-10-2018 TSH58p_01885 3efca1ed6a16f02ef976eb8efdd5f897 294 SUPERFAMILY SSF110849 36 126 8.02E-20 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily TSH58p_01885 3efca1ed6a16f02ef976eb8efdd5f897 294 Pfam PF02195 ParB-like nuclease domain 38 120 1.5E-15 T 14-10-2018 IPR003115 ParB/Sulfiredoxin TSH58p_00755 ce9f8f28360779f24e50108b69c02cda 343 Gene3D G3DSA:3.60.130.10 72 325 1.6E-30 T 14-10-2018 TSH58p_00755 ce9f8f28360779f24e50108b69c02cda 343 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 68 321 1.2E-14 T 14-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 TSH58p_00755 ce9f8f28360779f24e50108b69c02cda 343 SUPERFAMILY SSF51197 50 323 1.05E-31 T 14-10-2018 TSH58p_15225 b898aa57213b252c2e716dcbb1b3b841 180 PIRSF PIRSF002161 1 180 2.2E-69 T 14-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15225 b898aa57213b252c2e716dcbb1b3b841 180 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 2 180 43.691 T 14-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_15225 b898aa57213b252c2e716dcbb1b3b841 180 SUPERFAMILY SSF55282 4 179 4.0E-79 T 14-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15225 b898aa57213b252c2e716dcbb1b3b841 180 Gene3D G3DSA:3.30.1440.10 1 179 3.0E-81 T 14-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15225 b898aa57213b252c2e716dcbb1b3b841 180 ProSitePatterns PS00358 Ribosomal protein L5 signature. 58 74 - T 14-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15225 b898aa57213b252c2e716dcbb1b3b841 180 Pfam PF00281 Ribosomal protein L5 25 81 3.5E-28 T 14-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_15225 b898aa57213b252c2e716dcbb1b3b841 180 Pfam PF00673 ribosomal L5P family C-terminus 86 178 8.2E-43 T 14-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSH58p_26570 2dfbe1807e9449a9a7f7faa1552c383f 137 Pfam PF00856 SET domain 18 116 2.1E-8 T 14-10-2018 IPR001214 SET domain GO:0005515 TSH58p_26570 2dfbe1807e9449a9a7f7faa1552c383f 137 Gene3D G3DSA:2.170.270.10 6 127 1.2E-12 T 14-10-2018 TSH58p_26570 2dfbe1807e9449a9a7f7faa1552c383f 137 SUPERFAMILY SSF82199 9 120 1.44E-14 T 14-10-2018 TSH58p_19585 3157b88cd9f0ef5e50af14f0b1e2ee24 142 Pfam PF04892 VanZ like family 39 115 5.8E-9 T 14-10-2018 IPR006976 VanZ-like TSH58p_27850 80bfa355e8ad3a594ac6f1d2934349c7 337 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 35 290 6.1E-84 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 TSH58p_27850 80bfa355e8ad3a594ac6f1d2934349c7 337 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 35 317 3.2E-93 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 TSH58p_27850 80bfa355e8ad3a594ac6f1d2934349c7 337 PIRSF PIRSF006470 1 334 2.1E-117 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 TSH58p_27850 80bfa355e8ad3a594ac6f1d2934349c7 337 Gene3D G3DSA:3.40.190.170 28 337 4.4E-108 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily TSH58p_16740 d45347e3d9366868e2508b2d4baae805 155 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 16 144 1.7E-43 T 14-10-2018 IPR003791 Protein of unknown function UPF0178 TSH58p_16740 d45347e3d9366868e2508b2d4baae805 155 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 2 146 27.949 T 14-10-2018 IPR003791 Protein of unknown function UPF0178 TSH58p_05685 643a679043137ecd39caa56a99250865 202 Gene3D G3DSA:1.20.1050.10 82 197 1.0E-38 T 14-10-2018 TSH58p_05685 643a679043137ecd39caa56a99250865 202 SUPERFAMILY SSF52833 1 79 6.6E-22 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_05685 643a679043137ecd39caa56a99250865 202 SUPERFAMILY SSF47616 77 192 2.09E-28 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily TSH58p_05685 643a679043137ecd39caa56a99250865 202 Gene3D G3DSA:3.40.30.10 1 81 2.2E-24 T 14-10-2018 TSH58p_05685 643a679043137ecd39caa56a99250865 202 Pfam PF02798 Glutathione S-transferase, N-terminal domain 2 76 2.0E-15 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 TSH58p_05685 643a679043137ecd39caa56a99250865 202 Pfam PF00043 Glutathione S-transferase, C-terminal domain 135 192 2.8E-11 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal TSH58p_20955 d67ba40dbb6fa443beed85c277bdbad8 199 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 56 186 3.7E-23 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ TSH58p_21315 c76b2fd841dde54b8d2ebcd0a0b992b2 154 SUPERFAMILY SSF47188 23 148 5.23E-18 T 14-10-2018 IPR035938 Hemerythrin-like superfamily TSH58p_21315 c76b2fd841dde54b8d2ebcd0a0b992b2 154 Gene3D G3DSA:1.20.120.50 16 153 3.7E-18 T 14-10-2018 IPR035938 Hemerythrin-like superfamily TSH58p_21315 c76b2fd841dde54b8d2ebcd0a0b992b2 154 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 26 147 3.9E-17 T 14-10-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 TSH58p_21315 c76b2fd841dde54b8d2ebcd0a0b992b2 154 Pfam PF01814 Hemerythrin HHE cation binding domain 31 136 5.1E-7 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 TSH58p_13465 540ae10c9e4bcce32d8a8fb8f1975f36 369 Gene3D G3DSA:1.10.3720.10 125 357 4.4E-17 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_13465 540ae10c9e4bcce32d8a8fb8f1975f36 369 SUPERFAMILY SSF161098 133 348 5.36E-11 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_13465 540ae10c9e4bcce32d8a8fb8f1975f36 369 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 155 362 2.7E-36 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_23100 c693f6c25bb8b99f850681396f081eb6 446 Pfam PF06123 Inner membrane protein CreD 21 441 3.0E-92 T 14-10-2018 IPR010364 Uncharacterised protein family, inner membrane CreD TSH58p_29200 b0eff997eef213263bfe41609ddd62d0 77 Gene3D G3DSA:1.10.1200.10 7 76 9.3E-10 T 14-10-2018 IPR036736 ACP-like superfamily TSH58p_29200 b0eff997eef213263bfe41609ddd62d0 77 SUPERFAMILY SSF47336 12 69 9.64E-6 T 14-10-2018 IPR036736 ACP-like superfamily TSH58p_30670 8e3a797f8cd7f3dfeb2c022e00a5c91b 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 147 279 3.2E-13 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_30670 8e3a797f8cd7f3dfeb2c022e00a5c91b 283 Gene3D G3DSA:1.10.3720.10 7 283 6.1E-46 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_30670 8e3a797f8cd7f3dfeb2c022e00a5c91b 283 SUPERFAMILY SSF161098 10 274 1.7E-45 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_19060 50e67f48c2a855edc9ee18fe780523a2 300 Pfam PF01226 Formate/nitrite transporter 31 289 2.8E-71 T 14-10-2018 IPR000292 Formate/nitrite transporter GO:0016020|GO:0022857|GO:0055085 TSH58p_19060 50e67f48c2a855edc9ee18fe780523a2 300 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 185 195 - T 14-10-2018 IPR024002 Formate/nitrite transporter, conserved site TSH58p_19060 50e67f48c2a855edc9ee18fe780523a2 300 Gene3D G3DSA:1.20.1080.10 19 281 5.4E-84 T 14-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 TSH58p_25860 e62f76537997b1a1fb85dc77f3b8f033 338 Gene3D G3DSA:3.10.580.10 216 335 3.1E-41 T 14-10-2018 TSH58p_25860 e62f76537997b1a1fb85dc77f3b8f033 338 Pfam PF01380 SIS domain 62 190 9.5E-29 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TSH58p_25860 e62f76537997b1a1fb85dc77f3b8f033 338 Pfam PF00571 CBS domain 285 335 1.8E-9 T 14-10-2018 IPR000644 CBS domain TSH58p_25860 e62f76537997b1a1fb85dc77f3b8f033 338 Pfam PF00571 CBS domain 218 274 1.8E-5 T 14-10-2018 IPR000644 CBS domain TSH58p_25860 e62f76537997b1a1fb85dc77f3b8f033 338 Gene3D G3DSA:3.40.50.10490 21 215 4.0E-60 T 14-10-2018 TSH58p_25860 e62f76537997b1a1fb85dc77f3b8f033 338 PIRSF PIRSF004692 14 338 6.2E-127 T 14-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 TSH58p_25860 e62f76537997b1a1fb85dc77f3b8f033 338 SMART SM00116 290 337 0.021 T 14-10-2018 IPR000644 CBS domain TSH58p_25860 e62f76537997b1a1fb85dc77f3b8f033 338 SMART SM00116 227 275 0.21 T 14-10-2018 IPR000644 CBS domain TSH58p_25860 e62f76537997b1a1fb85dc77f3b8f033 338 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 63 328 1.6E-89 T 14-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 TSH58p_25860 e62f76537997b1a1fb85dc77f3b8f033 338 SUPERFAMILY SSF53697 28 321 2.89E-63 T 14-10-2018 TSH58p_03865 7c57c2b5e6e799e610b4d35d6cf4e835 416 SUPERFAMILY SSF103473 34 413 2.09E-57 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_03865 7c57c2b5e6e799e610b4d35d6cf4e835 416 ProSitePatterns PS00216 Sugar transport proteins signature 1. 92 108 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TSH58p_03865 7c57c2b5e6e799e610b4d35d6cf4e835 416 Pfam PF07690 Major Facilitator Superfamily 42 261 1.8E-27 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_03865 7c57c2b5e6e799e610b4d35d6cf4e835 416 Gene3D G3DSA:1.20.1250.20 31 413 2.5E-49 T 14-10-2018 TSH58p_30710 44c6ed5e8a94dbe17e4cc038b950f953 494 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 444 472 1.8E-6 T 14-10-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 TSH58p_30710 44c6ed5e8a94dbe17e4cc038b950f953 494 SUPERFAMILY SSF53383 76 434 5.03E-45 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_30710 44c6ed5e8a94dbe17e4cc038b950f953 494 Gene3D G3DSA:3.90.105.10 440 492 1.1E-12 T 14-10-2018 TSH58p_30710 44c6ed5e8a94dbe17e4cc038b950f953 494 Gene3D G3DSA:3.40.640.10 28 327 5.8E-64 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_30710 44c6ed5e8a94dbe17e4cc038b950f953 494 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 28 380 1.1E-42 T 14-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 TSH58p_12750 ff48e0bc6e0b20d95f8091cf20c38c08 268 Pfam PF09955 Predicted integral membrane protein (DUF2189) 76 198 8.8E-32 T 14-10-2018 IPR018692 Predicted integral membrane protein DUF2189 TSH58p_29060 7a17e2ca010a56ed1d784c51e49f47ca 52 Pfam PF11752 Protein of unknown function (DUF3309) 4 52 7.6E-24 T 14-10-2018 IPR021738 Protein of unknown function DUF3309 TSH58p_02050 72e1e050ff4f4fa9ace2a93c61b4709b 126 Gene3D G3DSA:3.40.250.10 10 126 9.6E-25 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily TSH58p_02050 72e1e050ff4f4fa9ace2a93c61b4709b 126 SMART SM00450 27 123 6.1E-20 T 14-10-2018 IPR001763 Rhodanese-like domain TSH58p_02050 72e1e050ff4f4fa9ace2a93c61b4709b 126 SUPERFAMILY SSF52821 6 126 7.2E-30 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily TSH58p_02050 72e1e050ff4f4fa9ace2a93c61b4709b 126 Pfam PF00581 Rhodanese-like domain 36 119 1.6E-13 T 14-10-2018 IPR001763 Rhodanese-like domain TSH58p_19235 952d53a4d8a5dd1d688697826f395298 150 Pfam PF07378 Flagellar protein FlbT 3 127 2.4E-42 T 14-10-2018 IPR009967 Flagellum biosynthesis repressor FlbT GO:0006402|GO:0048027|GO:1902209 TSH58p_16205 e08bce46ba48cce6f2dee2f243e47236 448 Gene3D G3DSA:2.40.160.60 28 448 2.6E-134 T 14-10-2018 TSH58p_16205 e08bce46ba48cce6f2dee2f243e47236 448 SUPERFAMILY SSF56935 28 444 4.07E-84 T 14-10-2018 TSH58p_16205 e08bce46ba48cce6f2dee2f243e47236 448 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 25 448 1.7E-103 T 14-10-2018 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) TSH58p_26115 acc169dd6179679d13b7ff3dc68013f1 309 Pfam PF01497 Periplasmic binding protein 55 279 2.3E-25 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain TSH58p_26115 acc169dd6179679d13b7ff3dc68013f1 309 SUPERFAMILY SSF53807 30 296 5.49E-60 T 14-10-2018 TSH58p_26115 acc169dd6179679d13b7ff3dc68013f1 309 Gene3D G3DSA:3.40.50.1980 49 296 1.2E-91 T 14-10-2018 TSH58p_26115 acc169dd6179679d13b7ff3dc68013f1 309 Gene3D G3DSA:3.40.50.12260 177 281 1.2E-91 T 14-10-2018 TSH58p_05065 cc01e15e51e878a82d629c9b794bd4ca 187 Gene3D G3DSA:2.160.10.10 6 177 1.2E-60 T 14-10-2018 TSH58p_05065 cc01e15e51e878a82d629c9b794bd4ca 187 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 92 126 5.2E-9 T 14-10-2018 IPR001451 Hexapeptide repeat TSH58p_05065 cc01e15e51e878a82d629c9b794bd4ca 187 SUPERFAMILY SSF51161 7 172 9.15E-46 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily TSH58p_00305 869364d7f1ac5bf678878d56707f8b89 395 Pfam PF04230 Polysaccharide pyruvyl transferase 36 321 2.7E-22 T 14-10-2018 IPR007345 Polysaccharide pyruvyl transferase TSH58p_04475 95f66abd70167ca795dbe3c7f91d01e3 218 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 15 195 3.1E-40 T 14-10-2018 TSH58p_04475 95f66abd70167ca795dbe3c7f91d01e3 218 Gene3D G3DSA:3.40.50.150 3 212 5.8E-52 T 14-10-2018 TSH58p_04475 95f66abd70167ca795dbe3c7f91d01e3 218 SUPERFAMILY SSF53335 2 208 1.16E-41 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_24375 579a2a8d14fd96074771355ff1893848 205 Gene3D G3DSA:1.10.3210.10 7 190 5.9E-42 T 14-10-2018 TSH58p_24375 579a2a8d14fd96074771355ff1893848 205 SUPERFAMILY SSF109604 12 182 3.77E-32 T 14-10-2018 TSH58p_27255 d0cf522477a347979bacdb957a7263f5 401 Pfam PF07690 Major Facilitator Superfamily 23 239 2.9E-20 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_27255 d0cf522477a347979bacdb957a7263f5 401 Gene3D G3DSA:1.20.1250.20 218 396 5.1E-17 T 14-10-2018 TSH58p_27255 d0cf522477a347979bacdb957a7263f5 401 SUPERFAMILY SSF103473 5 392 5.49E-50 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_27255 d0cf522477a347979bacdb957a7263f5 401 Gene3D G3DSA:1.20.1250.20 14 200 1.2E-20 T 14-10-2018 TSH58p_23320 24c17603ec76a6688576d8e4957d3908 175 Pfam PF05036 Sporulation related domain 85 159 2.3E-12 T 14-10-2018 IPR007730 Sporulation-like domain GO:0042834 TSH58p_23320 24c17603ec76a6688576d8e4957d3908 175 SUPERFAMILY SSF110997 85 159 1.24E-11 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 TSH58p_23320 24c17603ec76a6688576d8e4957d3908 175 Gene3D G3DSA:3.30.70.1070 79 159 2.0E-8 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 TSH58p_19425 44ecdbd505507c08ab61caf87290dcb7 270 SUPERFAMILY SSF56176 5 174 3.31E-52 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TSH58p_19425 44ecdbd505507c08ab61caf87290dcb7 270 Gene3D G3DSA:3.30.465.10 58 174 3.1E-38 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TSH58p_19425 44ecdbd505507c08ab61caf87290dcb7 270 Gene3D G3DSA:3.30.43.10 1 57 5.4E-20 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 TSH58p_19425 44ecdbd505507c08ab61caf87290dcb7 270 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 174 4.1E-47 T 14-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 TSH58p_12910 9a9c350103a0c08dd809a4f6acbee72d 327 Pfam PF01544 CorA-like Mg2+ transporter protein 28 323 1.3E-50 T 14-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 TSH58p_12910 9a9c350103a0c08dd809a4f6acbee72d 327 SUPERFAMILY SSF144083 262 324 1.31E-18 T 14-10-2018 TSH58p_12910 9a9c350103a0c08dd809a4f6acbee72d 327 Gene3D G3DSA:1.20.58.340 251 327 9.0E-24 T 14-10-2018 TSH58p_12910 9a9c350103a0c08dd809a4f6acbee72d 327 SUPERFAMILY SSF143865 1 260 6.67E-31 T 14-10-2018 TSH58p_02100 aee2a4656ed8306a832befdf5c95f965 270 Gene3D G3DSA:3.30.470.10 1 118 4.6E-38 T 14-10-2018 TSH58p_02100 aee2a4656ed8306a832befdf5c95f965 270 ProSitePatterns PS00770 Aminotransferases class-IV signature. 178 207 - T 14-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 TSH58p_02100 aee2a4656ed8306a832befdf5c95f965 270 Gene3D G3DSA:3.20.10.10 124 267 7.4E-39 T 14-10-2018 TSH58p_02100 aee2a4656ed8306a832befdf5c95f965 270 Pfam PF01063 Amino-transferase class IV 30 243 6.6E-52 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 TSH58p_02100 aee2a4656ed8306a832befdf5c95f965 270 SUPERFAMILY SSF56752 3 265 4.45E-73 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 TSH58p_07560 4aecc8f56736cafc8e6ccb725d6bf373 183 Gene3D G3DSA:1.25.40.10 21 176 1.9E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_27120 5d5ee92957364cff0fd3db9467f364f6 198 SUPERFAMILY SSF53056 57 141 6.64E-11 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 TSH58p_27120 5d5ee92957364cff0fd3db9467f364f6 198 Gene3D G3DSA:3.40.1050.10 43 183 9.6E-6 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 TSH58p_14055 23bfe11b20db48db07f22fac24ffc76b 142 Pfam PF01957 NfeD-like C-terminal, partner-binding 6 141 5.6E-24 T 14-10-2018 IPR002810 NfeD-like, C-terminal domain TSH58p_03530 2f4db5f96c667d1ffe9e06f18029f72f 395 SUPERFAMILY SSF56349 62 367 6.77E-50 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TSH58p_03530 2f4db5f96c667d1ffe9e06f18029f72f 395 Gene3D G3DSA:1.10.443.10 179 380 5.3E-47 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TSH58p_03530 2f4db5f96c667d1ffe9e06f18029f72f 395 Pfam PF00589 Phage integrase family 178 365 3.0E-30 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TSH58p_03530 2f4db5f96c667d1ffe9e06f18029f72f 395 Gene3D G3DSA:1.10.150.130 58 167 1.4E-10 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal TSH58p_17690 2f4db5f96c667d1ffe9e06f18029f72f 395 SUPERFAMILY SSF56349 62 367 6.77E-50 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TSH58p_17690 2f4db5f96c667d1ffe9e06f18029f72f 395 Gene3D G3DSA:1.10.443.10 179 380 5.3E-47 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TSH58p_17690 2f4db5f96c667d1ffe9e06f18029f72f 395 Pfam PF00589 Phage integrase family 178 365 3.0E-30 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TSH58p_17690 2f4db5f96c667d1ffe9e06f18029f72f 395 Gene3D G3DSA:1.10.150.130 58 167 1.4E-10 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal TSH58p_10535 9b03a7a8b258a95f9dd9f7df9f70bd3a 425 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 13 241 1.9E-98 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 TSH58p_10535 9b03a7a8b258a95f9dd9f7df9f70bd3a 425 SUPERFAMILY SSF51621 7 424 2.29E-144 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSH58p_10535 9b03a7a8b258a95f9dd9f7df9f70bd3a 425 Pfam PF00463 Isocitrate lyase family 11 241 2.9E-52 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 TSH58p_10535 9b03a7a8b258a95f9dd9f7df9f70bd3a 425 PIRSF PIRSF001362 2 425 1.2E-227 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 TSH58p_10535 9b03a7a8b258a95f9dd9f7df9f70bd3a 425 ProSitePatterns PS00161 Isocitrate lyase signature. 181 186 - T 14-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 TSH58p_10535 9b03a7a8b258a95f9dd9f7df9f70bd3a 425 Gene3D G3DSA:3.20.20.60 2 407 2.0E-171 T 14-10-2018 TSH58p_20195 99b15e9a7298fdd1dd4af3ba024ddcb4 436 Pfam PF02120 Flagellar hook-length control protein FliK 310 385 2.2E-17 T 14-10-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal TSH58p_20195 99b15e9a7298fdd1dd4af3ba024ddcb4 436 Gene3D G3DSA:3.30.750.140 283 390 5.4E-10 T 14-10-2018 IPR038610 FliK-like, C-terminal domain superfamily TSH58p_00505 74a9b93fb825510b826d3c6c6618ba95 307 SUPERFAMILY SSF53474 38 303 2.94E-50 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_00505 74a9b93fb825510b826d3c6c6618ba95 307 Pfam PF00756 Putative esterase 47 216 5.2E-13 T 14-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 TSH58p_00505 74a9b93fb825510b826d3c6c6618ba95 307 Gene3D G3DSA:3.40.50.1820 26 305 6.1E-65 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_01365 b01f68bcc3808c222d88a71feddf0812 325 Pfam PF02803 Thiolase, C-terminal domain 191 311 1.0E-5 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 TSH58p_01365 b01f68bcc3808c222d88a71feddf0812 325 Gene3D G3DSA:3.40.47.10 2 325 4.1E-94 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_01365 b01f68bcc3808c222d88a71feddf0812 325 SUPERFAMILY SSF53901 178 314 1.61E-26 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_01365 b01f68bcc3808c222d88a71feddf0812 325 SUPERFAMILY SSF53901 8 167 1.47E-14 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_05395 56c4a67952bd82951c83e8ddbef8a3cd 650 SUPERFAMILY SSF52172 526 649 1.24E-33 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_05395 56c4a67952bd82951c83e8ddbef8a3cd 650 Gene3D G3DSA:3.40.50.2300 523 650 2.1E-30 T 14-10-2018 TSH58p_05395 56c4a67952bd82951c83e8ddbef8a3cd 650 Pfam PF00072 Response regulator receiver domain 531 643 5.6E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_05395 56c4a67952bd82951c83e8ddbef8a3cd 650 SMART SM00448 529 643 2.8E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_02330 568bd414220e514e5c4fc6ddcb3e05be 234 Gene3D G3DSA:3.40.109.10 4 229 1.5E-68 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TSH58p_02330 568bd414220e514e5c4fc6ddcb3e05be 234 SUPERFAMILY SSF55469 13 231 7.2E-49 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TSH58p_02330 568bd414220e514e5c4fc6ddcb3e05be 234 Pfam PF00881 Nitroreductase family 17 208 3.7E-36 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TSH58p_15940 0c0cd2fab654993f61ba1edb41228bb3 680 Gene3D G3DSA:1.10.510.10 79 281 4.8E-15 T 14-10-2018 TSH58p_15940 0c0cd2fab654993f61ba1edb41228bb3 680 SMART SM00220 35 285 2.0E-4 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TSH58p_15940 0c0cd2fab654993f61ba1edb41228bb3 680 Gene3D G3DSA:3.30.200.20 87 110 4.8E-15 T 14-10-2018 TSH58p_15940 0c0cd2fab654993f61ba1edb41228bb3 680 SUPERFAMILY SSF56112 78 283 1.23E-17 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily TSH58p_16860 d805f262fdb6014ba86d56818f63bd4b 93 Gene3D G3DSA:1.10.10.1100 1 56 6.7E-15 T 14-10-2018 TSH58p_16860 d805f262fdb6014ba86d56818f63bd4b 93 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 48 1.1E-10 T 14-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain TSH58p_18020 3c2d18cf1a7312f03c345c0f4fb7d2da 324 ProSitePatterns PS00398 Site-specific recombinases signature 2. 56 68 - T 14-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 TSH58p_18020 3c2d18cf1a7312f03c345c0f4fb7d2da 324 Gene3D G3DSA:3.40.50.1390 2 126 3.6E-45 T 14-10-2018 TSH58p_18020 3c2d18cf1a7312f03c345c0f4fb7d2da 324 SUPERFAMILY SSF53041 1 137 1.44E-42 T 14-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 TSH58p_18020 3c2d18cf1a7312f03c345c0f4fb7d2da 324 Pfam PF00239 Resolvase, N terminal domain 4 136 3.5E-43 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 TSH58p_18020 3c2d18cf1a7312f03c345c0f4fb7d2da 324 ProSitePatterns PS00397 Site-specific recombinases active site. 6 14 - T 14-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 TSH58p_18020 3c2d18cf1a7312f03c345c0f4fb7d2da 324 SMART SM00857 3 137 3.1E-56 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 TSH58p_00090 49072bb807d5b71dcbcd881147475854 159 Pfam PF10087 Uncharacterized protein conserved in bacteria (DUF2325) 55 145 7.3E-26 T 14-10-2018 IPR016772 Uncharacterised conserved protein UCP020408 TSH58p_12535 c508ef38472e5c57aa0b558020d3ca63 278 Pfam PF00795 Carbon-nitrogen hydrolase 6 260 8.1E-50 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 TSH58p_12535 c508ef38472e5c57aa0b558020d3ca63 278 Gene3D G3DSA:3.60.110.10 2 274 4.5E-84 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TSH58p_12535 c508ef38472e5c57aa0b558020d3ca63 278 SUPERFAMILY SSF56317 1 267 9.94E-77 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TSH58p_25945 c57cec44a1bc4f8cc6ddd0e8cbe77705 143 Pfam PF13763 Domain of unknown function (DUF4167) 27 95 5.0E-32 T 14-10-2018 IPR025430 Domain of unknown function DUF4167 TSH58p_27940 c78e1f0013153273e58024301a23dd5e 1153 SUPERFAMILY SSF75553 481 645 2.35E-6 T 14-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 TSH58p_27940 c78e1f0013153273e58024301a23dd5e 1153 SMART SM00968 507 596 0.003 T 14-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 TSH58p_27940 c78e1f0013153273e58024301a23dd5e 1153 Gene3D G3DSA:3.40.50.300 895 1152 2.5E-45 T 14-10-2018 TSH58p_27940 c78e1f0013153273e58024301a23dd5e 1153 Gene3D G3DSA:3.40.50.300 3 277 1.6E-41 T 14-10-2018 TSH58p_27940 c78e1f0013153273e58024301a23dd5e 1153 PIRSF PIRSF005719 549 1152 9.7E-116 T 14-10-2018 IPR024704 Structural maintenance of chromosomes protein TSH58p_27940 c78e1f0013153273e58024301a23dd5e 1153 PIRSF PIRSF005719 1 542 3.4E-105 T 14-10-2018 IPR024704 Structural maintenance of chromosomes protein TSH58p_27940 c78e1f0013153273e58024301a23dd5e 1153 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1145 20.743 T 14-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 TSH58p_27940 c78e1f0013153273e58024301a23dd5e 1153 SUPERFAMILY SSF52540 3 1142 7.48E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_27940 c78e1f0013153273e58024301a23dd5e 1153 Pfam PF02463 RecF/RecN/SMC N terminal domain 4 1136 8.7E-57 T 14-10-2018 IPR003395 RecF/RecN/SMC, N-terminal TSH58p_32290 f36ea5660a6ef6295e2b80b1fd315de5 330 PIRSF PIRSF006470 3 327 1.3E-88 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 TSH58p_32290 f36ea5660a6ef6295e2b80b1fd315de5 330 Gene3D G3DSA:3.40.190.170 38 330 3.5E-99 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily TSH58p_32290 f36ea5660a6ef6295e2b80b1fd315de5 330 SUPERFAMILY SSF53850 32 303 6.42E-7 T 14-10-2018 TSH58p_32290 f36ea5660a6ef6295e2b80b1fd315de5 330 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 36 283 4.8E-70 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 TSH58p_32290 f36ea5660a6ef6295e2b80b1fd315de5 330 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 36 312 4.3E-78 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 TSH58p_19455 fccdd0d7fe49bf067c60ba4fa3eaf111 384 Gene3D G3DSA:3.40.50.2300 146 279 4.4E-81 T 14-10-2018 TSH58p_19455 fccdd0d7fe49bf067c60ba4fa3eaf111 384 Pfam PF13458 Periplasmic binding protein 26 380 2.5E-69 T 14-10-2018 IPR028081 Leucine-binding protein domain TSH58p_19455 fccdd0d7fe49bf067c60ba4fa3eaf111 384 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 258 276 6.6E-9 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_19455 fccdd0d7fe49bf067c60ba4fa3eaf111 384 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 27 43 6.6E-9 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_19455 fccdd0d7fe49bf067c60ba4fa3eaf111 384 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 49 65 6.6E-9 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_19455 fccdd0d7fe49bf067c60ba4fa3eaf111 384 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 68 86 6.6E-9 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_19455 fccdd0d7fe49bf067c60ba4fa3eaf111 384 SUPERFAMILY SSF53822 25 382 9.42E-81 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_19455 fccdd0d7fe49bf067c60ba4fa3eaf111 384 Gene3D G3DSA:3.40.50.2300 28 352 4.4E-81 T 14-10-2018 TSH58p_13790 35454d2b598450fae3a2318478ccd8e6 456 SUPERFAMILY SSF55073 42 147 5.49E-6 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_13790 35454d2b598450fae3a2318478ccd8e6 456 Gene3D G3DSA:3.30.70.270 40 190 2.5E-6 T 14-10-2018 TSH58p_31710 b883f6327c97571d5e9db752d992f1e4 269 SUPERFAMILY SSF161098 6 263 7.46E-52 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_31710 b883f6327c97571d5e9db752d992f1e4 269 Gene3D G3DSA:1.10.3720.10 13 263 6.4E-45 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_31710 b883f6327c97571d5e9db752d992f1e4 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 251 1.1E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_11580 2f2919ed74d5e2dc07ae5cf6656502f2 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 281 2.1E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_11580 2f2919ed74d5e2dc07ae5cf6656502f2 294 SUPERFAMILY SSF161098 15 286 1.44E-51 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_11580 2f2919ed74d5e2dc07ae5cf6656502f2 294 Gene3D G3DSA:1.10.3720.10 10 288 2.6E-47 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_27640 d94b3a15e15297f8d9b2b6276c06dce0 533 Pfam PF01471 Putative peptidoglycan binding domain 165 219 1.1E-8 T 14-10-2018 IPR002477 Peptidoglycan binding-like TSH58p_27640 d94b3a15e15297f8d9b2b6276c06dce0 533 SUPERFAMILY SSF47090 164 223 8.37E-11 T 14-10-2018 IPR036365 PGBD-like superfamily TSH58p_27640 d94b3a15e15297f8d9b2b6276c06dce0 533 Pfam PF03734 L,D-transpeptidase catalytic domain 247 408 6.1E-27 T 14-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 TSH58p_27640 d94b3a15e15297f8d9b2b6276c06dce0 533 SUPERFAMILY SSF141523 244 402 3.92E-23 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like TSH58p_19130 2ae92eccb43fdbd8798c345f4d8b209b 354 Pfam PF00669 Bacterial flagellin N-terminal helical region 6 138 2.9E-11 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 TSH58p_19130 2ae92eccb43fdbd8798c345f4d8b209b 354 Gene3D G3DSA:1.20.1330.10 47 202 1.3E-6 T 14-10-2018 TSH58p_19130 2ae92eccb43fdbd8798c345f4d8b209b 354 Pfam PF00700 Bacterial flagellin C-terminal helical region 273 354 1.9E-12 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 TSH58p_19130 2ae92eccb43fdbd8798c345f4d8b209b 354 SUPERFAMILY SSF64518 6 354 6.67E-21 T 14-10-2018 TSH58p_27225 a51761f13cfdde107c2fd93e7c790245 342 SUPERFAMILY SSF46785 261 331 2.5E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_27225 a51761f13cfdde107c2fd93e7c790245 342 PIRSF PIRSF019423 2 340 5.5E-108 T 14-10-2018 IPR011213 Nicotinic acid mononucleotide biosynthesis protein TSH58p_27225 a51761f13cfdde107c2fd93e7c790245 342 SUPERFAMILY SSF55811 42 145 3.45E-10 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TSH58p_27225 a51761f13cfdde107c2fd93e7c790245 342 Gene3D G3DSA:1.10.10.10 257 332 6.1E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_25425 88327e49d7b7853f0c9c7153b9e7c98c 971 SUPERFAMILY SSF50199 882 969 7.32E-5 T 14-10-2018 TSH58p_25425 88327e49d7b7853f0c9c7153b9e7c98c 971 SUPERFAMILY SSF51695 560 807 7.59E-23 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TSH58p_25425 88327e49d7b7853f0c9c7153b9e7c98c 971 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 562 666 3.1E-11 T 14-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 TSH58p_17095 c369f15bd5c114c2f053792de588b6ad 349 SUPERFAMILY SSF53901 3 207 1.01E-47 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_17095 c369f15bd5c114c2f053792de588b6ad 349 SUPERFAMILY SSF53901 210 347 1.27E-26 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_17095 c369f15bd5c114c2f053792de588b6ad 349 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 216 322 4.4E-11 T 14-10-2018 IPR012328 Chalcone/stilbene synthase, C-terminal TSH58p_17095 c369f15bd5c114c2f053792de588b6ad 349 PIRSF PIRSF000451 1 349 1.9E-107 T 14-10-2018 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 TSH58p_17095 c369f15bd5c114c2f053792de588b6ad 349 Gene3D G3DSA:3.40.47.10 211 347 7.0E-31 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_17095 c369f15bd5c114c2f053792de588b6ad 349 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 7 204 4.2E-19 T 14-10-2018 IPR001099 Chalcone/stilbene synthase, N-terminal TSH58p_17095 c369f15bd5c114c2f053792de588b6ad 349 Gene3D G3DSA:3.40.47.10 5 208 6.0E-59 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 TSH58p_28315 459f6962a2f2bd3a747e95251ca62289 288 Pfam PF08340 Domain of unknown function (DUF1732) 204 288 2.2E-33 T 14-10-2018 IPR013551 Domain of unknown function DUF1732 TSH58p_28315 459f6962a2f2bd3a747e95251ca62289 288 Pfam PF03755 YicC-like family, N-terminal region 1 151 3.6E-31 T 14-10-2018 IPR013527 YicC-like, N-terminal TSH58p_28315 459f6962a2f2bd3a747e95251ca62289 288 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 288 3.8E-63 T 14-10-2018 IPR005229 Conserved hypothetical protein CHP00255 TSH58p_00545 66628793f85f7d03bbe5515bc1d46f00 606 SUPERFAMILY SSF52540 384 581 9.46E-15 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_00545 66628793f85f7d03bbe5515bc1d46f00 606 SUPERFAMILY SSF90123 41 359 2.62E-18 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_00545 66628793f85f7d03bbe5515bc1d46f00 606 Gene3D G3DSA:3.40.50.300 374 591 1.1E-18 T 14-10-2018 TSH58p_00545 66628793f85f7d03bbe5515bc1d46f00 606 Pfam PF06472 ABC transporter transmembrane region 2 38 310 4.8E-40 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TSH58p_04180 f29b3c9978aec9ee4b3f32b3d05ccbce 238 Pfam PF13478 XdhC Rossmann domain 87 228 5.6E-44 T 14-10-2018 IPR027051 XdhC Rossmann domain TSH58p_04180 f29b3c9978aec9ee4b3f32b3d05ccbce 238 Gene3D G3DSA:3.40.50.720 86 234 6.8E-53 T 14-10-2018 TSH58p_24095 3ebcf9ff03be2e6a57419e7f0c804d96 219 Pfam PF00881 Nitroreductase family 18 185 4.7E-30 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TSH58p_24095 3ebcf9ff03be2e6a57419e7f0c804d96 219 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 8 210 3.5E-88 T 14-10-2018 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5523 TSH58p_24095 3ebcf9ff03be2e6a57419e7f0c804d96 219 SUPERFAMILY SSF55469 14 216 1.57E-55 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TSH58p_24095 3ebcf9ff03be2e6a57419e7f0c804d96 219 Gene3D G3DSA:3.40.109.10 2 189 3.9E-59 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TSH58p_08520 92c65465fc7d24c5f96614d1b80fd7c7 565 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 27 137 1.2E-15 T 14-10-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 TSH58p_08520 92c65465fc7d24c5f96614d1b80fd7c7 565 Pfam PF07196 Flagellin hook IN motif 156 213 1.6E-10 T 14-10-2018 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 TSH58p_08520 92c65465fc7d24c5f96614d1b80fd7c7 565 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 247 546 5.5E-42 T 14-10-2018 IPR010809 Flagellar hook-associated protein 2, C-terminal GO:0007155|GO:0009288 TSH58p_01320 6225e55151cd21d2974e34d3c7767174 357 Gene3D G3DSA:3.40.50.720 1 356 2.2E-100 T 14-10-2018 TSH58p_01320 6225e55151cd21d2974e34d3c7767174 357 SUPERFAMILY SSF51735 1 352 4.87E-23 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_16015 d2abfd531ba43104389b4363a263d009 477 Pfam PF01523 Putative modulator of DNA gyrase 37 327 7.6E-66 T 14-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TSH58p_16015 d2abfd531ba43104389b4363a263d009 477 SUPERFAMILY SSF111283 22 473 9.29E-130 T 14-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TSH58p_16015 d2abfd531ba43104389b4363a263d009 477 Gene3D G3DSA:3.30.2290.10 17 231 1.3E-19 T 14-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TSH58p_16015 d2abfd531ba43104389b4363a263d009 477 PIRSF PIRSF004919 18 476 1.8E-134 T 14-10-2018 IPR025502 TldD TSH58p_30820 35704e58a24baf707ee04ed1fece885e 500 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 21 439 4.9E-148 T 14-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane TSH58p_07425 b3243e1d99418272dbe0ff0edb691713 215 PIRSF PIRSF009320 3 215 7.6E-48 T 14-10-2018 TSH58p_07425 b3243e1d99418272dbe0ff0edb691713 215 Gene3D G3DSA:3.40.50.300 5 215 6.3E-44 T 14-10-2018 TSH58p_07425 b3243e1d99418272dbe0ff0edb691713 215 SUPERFAMILY SSF52540 4 213 2.55E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_07425 b3243e1d99418272dbe0ff0edb691713 215 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 7 147 4.4E-12 T 14-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TSH58p_00125 65b4943ff8d2b2159e1f775bff6e8612 301 TIGRFAM TIGR02797 exbB: tonB-system energizer ExbB 76 285 1.7E-97 T 14-10-2018 IPR014164 TonB-system energizer ExbB type-1 GO:0016020|GO:0022857|GO:0055085 TSH58p_00125 65b4943ff8d2b2159e1f775bff6e8612 301 Pfam PF01618 MotA/TolQ/ExbB proton channel family 149 269 6.3E-34 T 14-10-2018 IPR002898 MotA/TolQ/ExbB proton channel TSH58p_28365 832a75946b63cc36c2ed1110347d2318 479 Pfam PF09839 Uncharacterized protein conserved in bacteria (DUF2066) 81 270 5.2E-15 T 14-10-2018 IPR018642 Protein of unknown function DUF2066 TSH58p_10795 1a66977fc4e97f5dfb2a3bc573677de8 443 Pfam PF10129 OpgC protein 45 427 4.8E-66 T 14-10-2018 IPR014550 Uncharacterised conserved protein UCP028704, OpgC TSH58p_10795 1a66977fc4e97f5dfb2a3bc573677de8 443 PIRSF PIRSF028704 16 440 8.5E-69 T 14-10-2018 IPR014550 Uncharacterised conserved protein UCP028704, OpgC TSH58p_18165 4b599076a3f3af9c65ff3b8bcfb98d33 281 SUPERFAMILY SSF53098 22 229 9.86E-6 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily TSH58p_18165 4b599076a3f3af9c65ff3b8bcfb98d33 281 Pfam PF13546 DDE superfamily endonuclease 15 261 1.0E-34 T 14-10-2018 IPR038721 Transposase IS701-like, DDE domain TSH58p_15640 5e514ff416ac376283e8199aab459490 358 SMART SM00257 306 355 0.0079 T 14-10-2018 IPR018392 LysM domain TSH58p_15640 5e514ff416ac376283e8199aab459490 358 Pfam PF01476 LysM domain 308 352 1.4E-9 T 14-10-2018 IPR018392 LysM domain TSH58p_15640 5e514ff416ac376283e8199aab459490 358 SUPERFAMILY SSF54106 306 356 3.53E-5 T 14-10-2018 TSH58p_15640 5e514ff416ac376283e8199aab459490 358 Gene3D G3DSA:2.60.40.10 66 144 5.0E-5 T 14-10-2018 IPR013783 Immunoglobulin-like fold TSH58p_15640 5e514ff416ac376283e8199aab459490 358 Gene3D G3DSA:3.10.350.10 306 353 1.2E-12 T 14-10-2018 IPR036779 LysM domain superfamily TSH58p_21310 5cb1c2c2c77763435161f054511b2f34 255 SUPERFAMILY SSF64438 8 253 9.71E-82 T 14-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic TSH58p_21310 5cb1c2c2c77763435161f054511b2f34 255 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 29 244 1.4E-48 T 14-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase TSH58p_21310 5cb1c2c2c77763435161f054511b2f34 255 Gene3D G3DSA:3.60.140.10 1 255 4.9E-87 T 14-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily TSH58p_21310 5cb1c2c2c77763435161f054511b2f34 255 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 18 251 1.6E-69 T 14-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase TSH58p_30135 d62a45961cb8d5df75a60e9c76131fcf 563 Pfam PF10592 AIPR protein 259 457 9.9E-42 T 14-10-2018 IPR018891 Abortive bacteriophage infection, resistance TSH58p_29975 d62a45961cb8d5df75a60e9c76131fcf 563 Pfam PF10592 AIPR protein 259 457 9.9E-42 T 14-10-2018 IPR018891 Abortive bacteriophage infection, resistance TSH58p_11515 f542e76b1d113534d2e147379a36a72b 273 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 49 271 6.6E-78 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 TSH58p_11515 f542e76b1d113534d2e147379a36a72b 273 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 60 75 - T 14-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 TSH58p_11515 f542e76b1d113534d2e147379a36a72b 273 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 180 194 - T 14-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 TSH58p_11515 f542e76b1d113534d2e147379a36a72b 273 Pfam PF01209 ubiE/COQ5 methyltransferase family 44 271 7.5E-80 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 TSH58p_11515 f542e76b1d113534d2e147379a36a72b 273 SUPERFAMILY SSF53335 41 270 3.22E-42 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_11515 f542e76b1d113534d2e147379a36a72b 273 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 40 272 36.459 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 TSH58p_11515 f542e76b1d113534d2e147379a36a72b 273 Gene3D G3DSA:3.40.50.150 55 273 2.9E-72 T 14-10-2018 TSH58p_13395 8e54ba141cf1a9f62306497b7c7ff339 548 Gene3D G3DSA:3.30.70.270 28 140 1.7E-6 T 14-10-2018 TSH58p_13395 8e54ba141cf1a9f62306497b7c7ff339 548 Pfam PF00817 impB/mucB/samB family 28 159 1.4E-8 T 14-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 TSH58p_13395 8e54ba141cf1a9f62306497b7c7ff339 548 Gene3D G3DSA:2.30.40.20 30 82 1.7E-6 T 14-10-2018 TSH58p_13395 8e54ba141cf1a9f62306497b7c7ff339 548 SUPERFAMILY SSF56672 11 268 3.75E-40 T 14-10-2018 TSH58p_29785 35a933b3e6cd63b54f2cbf1c8d9afba7 312 Gene3D G3DSA:2.70.98.10 16 309 5.4E-80 T 14-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 TSH58p_29785 35a933b3e6cd63b54f2cbf1c8d9afba7 312 Pfam PF01263 Aldose 1-epimerase 31 305 7.0E-38 T 14-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 TSH58p_29785 35a933b3e6cd63b54f2cbf1c8d9afba7 312 SUPERFAMILY SSF74650 23 308 2.95E-54 T 14-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 TSH58p_02875 e79349c1d7b6d376b965bc229bb2c865 258 SUPERFAMILY SSF46894 173 237 1.33E-16 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_02875 e79349c1d7b6d376b965bc229bb2c865 258 Gene3D G3DSA:1.10.10.10 171 244 5.1E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_02875 e79349c1d7b6d376b965bc229bb2c865 258 Pfam PF00196 Bacterial regulatory proteins, luxR family 180 234 2.2E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_02875 e79349c1d7b6d376b965bc229bb2c865 258 SMART SM00421 178 235 2.9E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_02875 e79349c1d7b6d376b965bc229bb2c865 258 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 195 211 1.1E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_02875 e79349c1d7b6d376b965bc229bb2c865 258 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 195 1.1E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_02875 e79349c1d7b6d376b965bc229bb2c865 258 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 211 223 1.1E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_02875 e79349c1d7b6d376b965bc229bb2c865 258 Gene3D G3DSA:3.40.50.2300 28 156 1.1E-7 T 14-10-2018 TSH58p_02875 e79349c1d7b6d376b965bc229bb2c865 258 SUPERFAMILY SSF52172 27 147 3.61E-7 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_24360 967a6b4fa4534447c8fc001db6f3099c 394 SUPERFAMILY SSF47384 148 233 4.71E-17 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSH58p_24360 967a6b4fa4534447c8fc001db6f3099c 394 SMART SM00388 164 232 2.1E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_24360 967a6b4fa4534447c8fc001db6f3099c 394 Gene3D G3DSA:1.10.287.130 130 230 4.3E-17 T 14-10-2018 TSH58p_24360 967a6b4fa4534447c8fc001db6f3099c 394 PRINTS PR00344 Bacterial sensor protein C-terminal signature 351 369 7.3E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_24360 967a6b4fa4534447c8fc001db6f3099c 394 PRINTS PR00344 Bacterial sensor protein C-terminal signature 334 344 7.3E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_24360 967a6b4fa4534447c8fc001db6f3099c 394 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 388 7.3E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_24360 967a6b4fa4534447c8fc001db6f3099c 394 PRINTS PR00344 Bacterial sensor protein C-terminal signature 316 330 7.3E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSH58p_24360 967a6b4fa4534447c8fc001db6f3099c 394 Pfam PF00512 His Kinase A (phospho-acceptor) domain 165 232 2.0E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSH58p_24360 967a6b4fa4534447c8fc001db6f3099c 394 Gene3D G3DSA:3.30.565.10 243 392 7.1E-43 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_24360 967a6b4fa4534447c8fc001db6f3099c 394 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 280 389 2.9E-26 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_24360 967a6b4fa4534447c8fc001db6f3099c 394 SMART SM00387 279 391 8.2E-35 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSH58p_24360 967a6b4fa4534447c8fc001db6f3099c 394 SUPERFAMILY SSF55874 222 390 3.41E-44 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_12660 2321e191eabce250e3cd9b453bba1974 77 Pfam PF06620 Protein of unknown function (DUF1150) 41 77 1.1E-11 T 14-10-2018 IPR009531 Protein of unknown function DUF1150 TSH58p_11920 61cc875265bea220ee6936d80e84d7cf 119 Gene3D G3DSA:3.40.50.2300 1 118 2.9E-17 T 14-10-2018 TSH58p_11920 61cc875265bea220ee6936d80e84d7cf 119 Pfam PF00072 Response regulator receiver domain 1 111 1.8E-9 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_11920 61cc875265bea220ee6936d80e84d7cf 119 SUPERFAMILY SSF52172 1 116 1.42E-19 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_11920 61cc875265bea220ee6936d80e84d7cf 119 SMART SM00448 1 111 1.3E-8 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_04145 0d2d8e7769b2f9ccf0c01b88058ba3e5 327 Pfam PF02653 Branched-chain amino acid transport system / permease component 47 304 2.6E-33 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_26790 65c6537151d48ce858116d49e86dbdf9 404 Pfam PF10129 OpgC protein 3 381 1.8E-70 T 14-10-2018 IPR014550 Uncharacterised conserved protein UCP028704, OpgC TSH58p_26790 65c6537151d48ce858116d49e86dbdf9 404 PIRSF PIRSF028704 1 402 4.6E-67 T 14-10-2018 IPR014550 Uncharacterised conserved protein UCP028704, OpgC TSH58p_09150 75cec427dc4b54837db27620822a4651 413 Gene3D G3DSA:3.40.50.2000 195 386 4.8E-67 T 14-10-2018 TSH58p_09150 75cec427dc4b54837db27620822a4651 413 Pfam PF00534 Glycosyl transferases group 1 215 379 1.7E-31 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 TSH58p_09150 75cec427dc4b54837db27620822a4651 413 SUPERFAMILY SSF53756 33 405 7.07E-84 T 14-10-2018 TSH58p_09150 75cec427dc4b54837db27620822a4651 413 Gene3D G3DSA:3.40.50.2000 56 399 4.8E-67 T 14-10-2018 TSH58p_09150 75cec427dc4b54837db27620822a4651 413 Pfam PF13439 Glycosyltransferase Family 4 44 197 1.3E-27 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TSH58p_00510 9c927c51b9ad00aee72a204aa8d6ded1 220 Gene3D G3DSA:3.40.50.150 2 220 1.2E-76 T 14-10-2018 TSH58p_00510 9c927c51b9ad00aee72a204aa8d6ded1 220 Pfam PF01596 O-methyltransferase 21 219 1.1E-66 T 14-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 TSH58p_00510 9c927c51b9ad00aee72a204aa8d6ded1 220 SUPERFAMILY SSF53335 11 220 5.78E-50 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_04175 5fbaa0792d601736118b0bc7b60a764c 536 SUPERFAMILY SSF53448 342 529 1.53E-38 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_04175 5fbaa0792d601736118b0bc7b60a764c 536 SUPERFAMILY SSF53218 182 305 4.87E-16 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSH58p_04175 5fbaa0792d601736118b0bc7b60a764c 536 PIRSF PIRSF036626 1 536 1.2E-193 T 14-10-2018 IPR012184 Bifunctional molybdopterin binding protein /nucleotidyl transferase, putative TSH58p_04175 5fbaa0792d601736118b0bc7b60a764c 536 Gene3D G3DSA:3.40.980.10 149 303 6.0E-14 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSH58p_04175 5fbaa0792d601736118b0bc7b60a764c 536 Pfam PF12804 MobA-like NTP transferase domain 346 509 2.9E-41 T 14-10-2018 IPR025877 MobA-like NTP transferase TSH58p_04175 5fbaa0792d601736118b0bc7b60a764c 536 SMART SM00852 171 302 1.9E-5 T 14-10-2018 IPR001453 MoaB/Mog domain TSH58p_04175 5fbaa0792d601736118b0bc7b60a764c 536 Gene3D G3DSA:3.90.550.10 341 535 1.3E-59 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_06770 ad5407b443ff28a4e04cbb9027c086d5 448 Pfam PF03109 ABC1 family 104 218 1.1E-26 T 14-10-2018 IPR004147 UbiB domain TSH58p_06770 ad5407b443ff28a4e04cbb9027c086d5 448 SUPERFAMILY SSF56112 87 302 2.88E-20 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily TSH58p_00175 b24b45e071b816200422a7092f1bd01d 603 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 417 538 2.2E-27 T 14-10-2018 IPR025299 CstA, C-terminal domain TSH58p_00175 b24b45e071b816200422a7092f1bd01d 603 Pfam PF02554 Carbon starvation protein CstA 4 368 2.2E-132 T 14-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 TSH58p_00260 f793f3cd67f45293ba2f0e5c30c2bdbe 234 Pfam PF03741 Integral membrane protein TerC family 12 184 2.2E-45 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 TSH58p_00260 f793f3cd67f45293ba2f0e5c30c2bdbe 234 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 9 185 6.3E-68 T 14-10-2018 IPR022301 Integral membrane protein YjbE TSH58p_24315 49a666ad335c447c0b8f11f98db66ba3 867 TIGRFAM TIGR02302 aProt_lowcomp: TIGR02302 family protein 31 866 7.9E-176 T 14-10-2018 IPR012683 Conserved hypothetical protein CHP02302, transmembrane TSH58p_24315 49a666ad335c447c0b8f11f98db66ba3 867 Pfam PF13779 Domain of unknown function (DUF4175) 39 865 2.6E-275 T 14-10-2018 IPR012683 Conserved hypothetical protein CHP02302, transmembrane TSH58p_28630 80e23d97450b99abdc10f6be57c7c6e0 293 SUPERFAMILY SSF48097 180 278 2.02E-7 T 14-10-2018 IPR036305 RGS domain superfamily TSH58p_28630 80e23d97450b99abdc10f6be57c7c6e0 293 Gene3D G3DSA:1.20.58.1850 175 283 6.7E-6 T 14-10-2018 TSH58p_30315 446451bcb55d2a51c633da9950ec7e2a 348 Pfam PF05940 NnrS protein 2 347 3.0E-69 T 14-10-2018 IPR010266 NnrS TSH58p_23765 bd4863ec74d0da0871b0598284e417bf 225 Pfam PF13701 Transposase DDE domain group 1 15 223 3.7E-70 T 14-10-2018 IPR025668 Transposase DDE domain TSH58p_03120 5643f7cc5678417191329981aae918c4 342 Gene3D G3DSA:1.10.260.40 3 63 2.9E-5 T 14-10-2018 TSH58p_03120 5643f7cc5678417191329981aae918c4 342 Pfam PF13614 AAA domain 81 257 2.1E-48 T 14-10-2018 IPR025669 AAA domain TSH58p_03120 5643f7cc5678417191329981aae918c4 342 SUPERFAMILY SSF52540 81 334 8.24E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_03120 5643f7cc5678417191329981aae918c4 342 PRINTS PR00091 Nitrogenase component II signature 85 98 7.3E-5 T 14-10-2018 TSH58p_03120 5643f7cc5678417191329981aae918c4 342 PRINTS PR00091 Nitrogenase component II signature 107 122 7.3E-5 T 14-10-2018 TSH58p_03120 5643f7cc5678417191329981aae918c4 342 Gene3D G3DSA:3.40.50.300 77 337 5.7E-69 T 14-10-2018 TSH58p_27855 6f271fb1b611c4234a09d1654c4f2d06 423 SUPERFAMILY SSF48239 84 358 7.85E-8 T 14-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TSH58p_02390 0d6823b9d353bfface13b50401556b58 398 SMART SM00382 53 250 9.8E-20 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_02390 0d6823b9d353bfface13b50401556b58 398 Pfam PF00005 ABC transporter 46 192 2.5E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_02390 0d6823b9d353bfface13b50401556b58 398 SUPERFAMILY SSF54631 274 393 9.25E-12 T 14-10-2018 TSH58p_02390 0d6823b9d353bfface13b50401556b58 398 Gene3D G3DSA:3.40.50.300 32 308 1.7E-77 T 14-10-2018 TSH58p_02390 0d6823b9d353bfface13b50401556b58 398 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_02390 0d6823b9d353bfface13b50401556b58 398 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 36 394 2.9E-136 T 14-10-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 TSH58p_02390 0d6823b9d353bfface13b50401556b58 398 SUPERFAMILY SSF52540 32 271 2.16E-74 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_31695 e9ce65b21415cc4efad7b0ea5b62194b 349 SUPERFAMILY SSF56112 16 327 1.91E-57 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily TSH58p_31695 e9ce65b21415cc4efad7b0ea5b62194b 349 Pfam PF01636 Phosphotransferase enzyme family 36 260 3.5E-33 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase TSH58p_31695 e9ce65b21415cc4efad7b0ea5b62194b 349 Gene3D G3DSA:3.90.1200.10 127 324 3.5E-22 T 14-10-2018 TSH58p_28275 b68c9c07da792158d7bccfecfdbe17d6 346 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 9 341 5.8E-121 T 14-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 TSH58p_28275 b68c9c07da792158d7bccfecfdbe17d6 346 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 7 344 37.031 T 14-10-2018 IPR037510 4-hydroxythreonine-4-phosphate dehydrogenase GO:0042823|GO:0050570 KEGG: 00750+1.1.1.262 TSH58p_28275 b68c9c07da792158d7bccfecfdbe17d6 346 SUPERFAMILY SSF53659 8 344 1.07E-107 T 14-10-2018 TSH58p_28275 b68c9c07da792158d7bccfecfdbe17d6 346 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 53 337 8.8E-102 T 14-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 TSH58p_28275 b68c9c07da792158d7bccfecfdbe17d6 346 Gene3D G3DSA:3.40.718.10 7 345 3.3E-119 T 14-10-2018 TSH58p_23580 a1e6b3404008ccc98d0d5220cb45110f 198 Pfam PF09860 Uncharacterized protein conserved in bacteria (DUF2087) 102 171 5.6E-24 T 14-10-2018 IPR018656 Domain of unknown function DUF2087 TSH58p_10375 606818ddea17596a62eb00947e6191e3 841 Pfam PF02687 FtsX-like permease family 750 830 4.2E-8 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 TSH58p_19195 cb6e8f1410dfb309c1b075e6f1b2b21b 123 PIRSF PIRSF002889 2 123 2.2E-15 T 14-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 TSH58p_19195 cb6e8f1410dfb309c1b075e6f1b2b21b 123 Pfam PF00460 Flagella basal body rod protein 10 32 1.2E-4 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 TSH58p_31640 d443fd25c0e2eedad4ea32a6916d1275 323 SUPERFAMILY SSF56317 1 297 7.59E-77 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TSH58p_31640 d443fd25c0e2eedad4ea32a6916d1275 323 Gene3D G3DSA:3.60.110.10 1 282 1.3E-103 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TSH58p_31640 d443fd25c0e2eedad4ea32a6916d1275 323 ProSitePatterns PS00921 Nitrilases / cyanide hydratase active site signature. 160 173 - T 14-10-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 TSH58p_31640 d443fd25c0e2eedad4ea32a6916d1275 323 Pfam PF00795 Carbon-nitrogen hydrolase 5 274 6.5E-56 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 TSH58p_13695 21383ee33f658d7d4c6817d1b054a82e 470 Pfam PF01551 Peptidase family M23 367 457 2.7E-20 T 14-10-2018 IPR016047 Peptidase M23 TSH58p_13695 21383ee33f658d7d4c6817d1b054a82e 470 SUPERFAMILY SSF51261 298 458 2.98E-27 T 14-10-2018 IPR011055 Duplicated hybrid motif TSH58p_13695 21383ee33f658d7d4c6817d1b054a82e 470 Gene3D G3DSA:2.70.70.10 327 461 2.1E-24 T 14-10-2018 IPR011055 Duplicated hybrid motif TSH58p_29595 9918f68574249493ff2d5e236d4df998 334 Pfam PF01435 Peptidase family M48 97 294 8.2E-29 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 TSH58p_29595 9918f68574249493ff2d5e236d4df998 334 Gene3D G3DSA:3.30.2010.10 84 172 3.1E-22 T 14-10-2018 TSH58p_23515 b3e7fb86ac975030b228508ca1595033 233 SUPERFAMILY SSF89260 72 156 4.45E-5 T 14-10-2018 TSH58p_23515 b3e7fb86ac975030b228508ca1595033 233 Gene3D G3DSA:2.60.120.380 53 173 3.6E-7 T 14-10-2018 TSH58p_28175 1ba4a5cef4f7edab7958394c6616f992 144 Pfam PF06170 Protein of unknown function (DUF983) 30 114 3.9E-30 T 14-10-2018 IPR009325 Protein of unknown function DUF983 TSH58p_16510 0508c2a62e61d456ac3451dac0bc7598 338 Gene3D G3DSA:3.90.550.10 12 241 4.0E-31 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_16510 0508c2a62e61d456ac3451dac0bc7598 338 SUPERFAMILY SSF53448 26 239 1.41E-35 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_16510 0508c2a62e61d456ac3451dac0bc7598 338 Pfam PF00535 Glycosyl transferase family 2 29 195 5.2E-21 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_15805 e4fb50021461db0633b96a701cfdec58 190 SUPERFAMILY SSF48452 57 185 1.5E-25 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_15805 e4fb50021461db0633b96a701cfdec58 190 SMART SM00028 138 171 0.036 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_15805 e4fb50021461db0633b96a701cfdec58 190 SMART SM00028 70 103 100.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_15805 e4fb50021461db0633b96a701cfdec58 190 SMART SM00028 104 137 9.8E-6 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSH58p_15805 e4fb50021461db0633b96a701cfdec58 190 Pfam PF13432 Tetratricopeptide repeat 109 169 9.1E-7 T 14-10-2018 TSH58p_15805 e4fb50021461db0633b96a701cfdec58 190 Gene3D G3DSA:1.25.40.10 61 185 3.7E-23 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_13900 f88df774c89e974c1b5efbeaf91272d5 221 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_13900 f88df774c89e974c1b5efbeaf91272d5 221 SUPERFAMILY SSF52172 1 133 1.31E-26 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_13900 f88df774c89e974c1b5efbeaf91272d5 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 8.5E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_13900 f88df774c89e974c1b5efbeaf91272d5 221 SMART SM00448 2 120 3.0E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_13900 f88df774c89e974c1b5efbeaf91272d5 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 3.0E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_13900 f88df774c89e974c1b5efbeaf91272d5 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 3.0E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_13900 f88df774c89e974c1b5efbeaf91272d5 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 3.0E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_13900 f88df774c89e974c1b5efbeaf91272d5 221 SUPERFAMILY SSF46894 143 214 3.74E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSH58p_13900 f88df774c89e974c1b5efbeaf91272d5 221 Gene3D G3DSA:3.40.50.12740 3 214 1.7E-52 T 14-10-2018 TSH58p_13900 f88df774c89e974c1b5efbeaf91272d5 221 Pfam PF00072 Response regulator receiver domain 4 119 5.1E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_13900 f88df774c89e974c1b5efbeaf91272d5 221 SMART SM00421 152 209 3.7E-21 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSH58p_22835 10e1a5f94f0df629c83a0097bd1f87cf 388 PIRSF PIRSF019422 170 388 1.6E-83 T 14-10-2018 IPR026044 Membrane-bound lytic murein transglycosylase A TSH58p_22835 10e1a5f94f0df629c83a0097bd1f87cf 388 PIRSF PIRSF019422 6 174 5.6E-23 T 14-10-2018 IPR026044 Membrane-bound lytic murein transglycosylase A TSH58p_22835 10e1a5f94f0df629c83a0097bd1f87cf 388 Pfam PF06725 3D domain 301 375 4.6E-20 T 14-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 TSH58p_22835 10e1a5f94f0df629c83a0097bd1f87cf 388 SMART SM00925 150 282 2.2E-68 T 14-10-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 TSH58p_22835 10e1a5f94f0df629c83a0097bd1f87cf 388 Gene3D G3DSA:2.40.40.10 288 378 3.8E-85 T 14-10-2018 IPR036908 RlpA-like domain superfamily TSH58p_22835 10e1a5f94f0df629c83a0097bd1f87cf 388 Gene3D G3DSA:2.40.40.10 58 148 5.0E-26 T 14-10-2018 IPR036908 RlpA-like domain superfamily TSH58p_22835 10e1a5f94f0df629c83a0097bd1f87cf 388 SUPERFAMILY SSF50685 47 380 2.69E-112 T 14-10-2018 IPR036908 RlpA-like domain superfamily TSH58p_22835 10e1a5f94f0df629c83a0097bd1f87cf 388 Pfam PF03562 MltA specific insert domain 64 282 6.6E-66 T 14-10-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 TSH58p_22835 10e1a5f94f0df629c83a0097bd1f87cf 388 Gene3D G3DSA:2.40.240.50 149 171 5.0E-26 T 14-10-2018 TSH58p_22835 10e1a5f94f0df629c83a0097bd1f87cf 388 Gene3D G3DSA:2.40.240.50 176 287 3.8E-85 T 14-10-2018 TSH58p_07000 0a0079bca01854f9f070ce70f04c88e3 439 Gene3D G3DSA:1.20.1090.10 207 436 8.1E-57 T 14-10-2018 TSH58p_07000 0a0079bca01854f9f070ce70f04c88e3 439 SUPERFAMILY SSF56796 28 436 4.97E-95 T 14-10-2018 TSH58p_07000 0a0079bca01854f9f070ce70f04c88e3 439 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 194 222 - T 14-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 TSH58p_07000 0a0079bca01854f9f070ce70f04c88e3 439 Gene3D G3DSA:3.40.50.1970 17 205 2.1E-50 T 14-10-2018 TSH58p_07000 0a0079bca01854f9f070ce70f04c88e3 439 Pfam PF00465 Iron-containing alcohol dehydrogenase 28 428 2.8E-100 T 14-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 TSH58p_09515 b1131d83a5f87cd6ba722e5a4ac34533 144 Pfam PF04138 GtrA-like protein 22 141 1.1E-22 T 14-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 TSH58p_24010 eb4d3cdd826f6f1ae9c6c51d057e1870 295 Pfam PF02653 Branched-chain amino acid transport system / permease component 17 283 4.5E-37 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_08165 f96c3d98294b8edcfb9844b87f241e03 205 Pfam PF11233 Protein of unknown function (DUF3035) 40 183 1.1E-46 T 14-10-2018 IPR021395 Protein of unknown function DUF3035 TSH58p_14675 fef26ccb03f90cbf9757cbb28c0bf7bc 130 Pfam PF05071 NADH ubiquinone oxidoreductase subunit NDUFA12 24 129 3.0E-25 T 14-10-2018 IPR007763 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 GO:0008137|GO:0009055|GO:0016020 Reactome: R-HSA-6799198 TSH58p_28995 3c0e9aa4e9a3393b7355b4b26ab8f061 298 Gene3D G3DSA:1.10.3720.10 77 292 2.1E-19 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_28995 3c0e9aa4e9a3393b7355b4b26ab8f061 298 SUPERFAMILY SSF161098 93 279 3.14E-25 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_28995 3c0e9aa4e9a3393b7355b4b26ab8f061 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 293 1.4E-13 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_11875 ebf3d312f0753ada124a3557fbf36dc4 300 SUPERFAMILY SSF88946 16 118 2.09E-37 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_11875 ebf3d312f0753ada124a3557fbf36dc4 300 Gene3D G3DSA:1.20.140.160 137 289 8.8E-21 T 14-10-2018 TSH58p_11875 ebf3d312f0753ada124a3557fbf36dc4 300 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 256 282 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_11875 ebf3d312f0753ada124a3557fbf36dc4 300 Pfam PF04542 Sigma-70 region 2 50 119 8.6E-20 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TSH58p_11875 ebf3d312f0753ada124a3557fbf36dc4 300 Pfam PF04545 Sigma-70, region 4 233 284 6.0E-18 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 TSH58p_11875 ebf3d312f0753ada124a3557fbf36dc4 300 SUPERFAMILY SSF88659 193 288 1.72E-22 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSH58p_11875 ebf3d312f0753ada124a3557fbf36dc4 300 PIRSF PIRSF000770 16 292 1.2E-34 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_11875 ebf3d312f0753ada124a3557fbf36dc4 300 PRINTS PR00046 Major sigma-70 factor signature 237 249 3.2E-24 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_11875 ebf3d312f0753ada124a3557fbf36dc4 300 PRINTS PR00046 Major sigma-70 factor signature 271 282 3.2E-24 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_11875 ebf3d312f0753ada124a3557fbf36dc4 300 PRINTS PR00046 Major sigma-70 factor signature 98 106 3.2E-24 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_11875 ebf3d312f0753ada124a3557fbf36dc4 300 PRINTS PR00046 Major sigma-70 factor signature 74 87 3.2E-24 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_11875 ebf3d312f0753ada124a3557fbf36dc4 300 PRINTS PR00046 Major sigma-70 factor signature 256 271 3.2E-24 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_11875 ebf3d312f0753ada124a3557fbf36dc4 300 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 74 87 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSH58p_11875 ebf3d312f0753ada124a3557fbf36dc4 300 Gene3D G3DSA:1.10.601.10 7 122 1.5E-31 T 14-10-2018 TSH58p_11875 ebf3d312f0753ada124a3557fbf36dc4 300 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 46 285 6.1E-34 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TSH58p_05990 fcd1b008cc687f68842776bbd2c7f99f 427 SUPERFAMILY SSF53067 181 421 1.04E-28 T 14-10-2018 TSH58p_05990 fcd1b008cc687f68842776bbd2c7f99f 427 Pfam PF00012 Hsp70 protein 307 393 6.0E-5 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TSH58p_05990 fcd1b008cc687f68842776bbd2c7f99f 427 Pfam PF00012 Hsp70 protein 101 232 3.9E-9 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TSH58p_05990 fcd1b008cc687f68842776bbd2c7f99f 427 SUPERFAMILY SSF53067 2 176 1.07E-26 T 14-10-2018 TSH58p_05990 fcd1b008cc687f68842776bbd2c7f99f 427 Gene3D G3DSA:3.30.420.40 1 184 3.7E-21 T 14-10-2018 TSH58p_22865 11b3814d4a4d074b4e804934ed55c11c 236 SUPERFAMILY SSF53335 50 230 3.22E-37 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_22865 11b3814d4a4d074b4e804934ed55c11c 236 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 35 230 29.843 T 14-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 TSH58p_22865 11b3814d4a4d074b4e804934ed55c11c 236 Gene3D G3DSA:3.40.50.150 47 235 3.8E-61 T 14-10-2018 TSH58p_22865 11b3814d4a4d074b4e804934ed55c11c 236 PIRSF PIRSF005461 17 236 1.9E-74 T 14-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 TSH58p_22865 11b3814d4a4d074b4e804934ed55c11c 236 Pfam PF01728 FtsJ-like methyltransferase 51 229 3.4E-56 T 14-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 TSH58p_25710 5cc6de0345a411117764ca46daba0a3c 201 Pfam PF16917 Biotin/lipoate A/B protein ligase family 9 189 8.4E-58 T 14-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 TSH58p_25710 5cc6de0345a411117764ca46daba0a3c 201 SUPERFAMILY SSF55681 56 192 7.46E-6 T 14-10-2018 TSH58p_25710 5cc6de0345a411117764ca46daba0a3c 201 Gene3D G3DSA:3.30.930.10 17 192 1.6E-41 T 14-10-2018 TSH58p_00670 5f8cbbcb3063318bd41269e3442932d9 215 Pfam PF01914 MarC family integral membrane protein 10 210 8.9E-52 T 14-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 TSH58p_00670 5f8cbbcb3063318bd41269e3442932d9 215 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 11 208 1.5E-45 T 14-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 TSH58p_14785 d09022934d09e7d3e251e4ea9c0f21a0 429 Pfam PF01019 Gamma-glutamyltranspeptidase 42 262 8.1E-26 T 14-10-2018 TSH58p_14785 d09022934d09e7d3e251e4ea9c0f21a0 429 SUPERFAMILY SSF56235 25 329 8.68E-43 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_14785 d09022934d09e7d3e251e4ea9c0f21a0 429 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 119 138 7.1E-11 T 14-10-2018 TSH58p_14785 d09022934d09e7d3e251e4ea9c0f21a0 429 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 49 74 7.1E-11 T 14-10-2018 TSH58p_14785 d09022934d09e7d3e251e4ea9c0f21a0 429 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 242 261 7.1E-11 T 14-10-2018 TSH58p_14785 d09022934d09e7d3e251e4ea9c0f21a0 429 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 101 119 7.1E-11 T 14-10-2018 TSH58p_01925 57688cd1b2c0feba30b63eab54d1ab82 333 Pfam PF00535 Glycosyl transferase family 2 29 141 2.6E-29 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_01925 57688cd1b2c0feba30b63eab54d1ab82 333 SUPERFAMILY SSF53448 25 257 1.38E-44 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_01925 57688cd1b2c0feba30b63eab54d1ab82 333 Gene3D G3DSA:3.90.550.10 11 259 2.8E-34 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_16730 1aa55bab53febb4588d214a6684c6921 227 Gene3D G3DSA:3.10.100.10 40 206 1.1E-9 T 14-10-2018 IPR016186 C-type lectin-like/link domain superfamily TSH58p_16730 1aa55bab53febb4588d214a6684c6921 227 SUPERFAMILY SSF56436 35 204 1.41E-35 T 14-10-2018 IPR016187 C-type lectin fold TSH58p_27155 1bbc5a1ced198eb356d101375dbc94fe 553 Gene3D G3DSA:1.20.58.220 438 532 2.3E-7 T 14-10-2018 IPR038078 PhoU-like domain superfamily TSH58p_27155 1bbc5a1ced198eb356d101375dbc94fe 553 Gene3D G3DSA:1.20.58.220 331 425 3.6E-11 T 14-10-2018 IPR038078 PhoU-like domain superfamily TSH58p_27155 1bbc5a1ced198eb356d101375dbc94fe 553 Pfam PF01895 PhoU domain 337 416 1.3E-9 T 14-10-2018 IPR026022 PhoU domain TSH58p_27155 1bbc5a1ced198eb356d101375dbc94fe 553 Pfam PF01895 PhoU domain 443 525 1.3E-5 T 14-10-2018 IPR026022 PhoU domain TSH58p_27155 1bbc5a1ced198eb356d101375dbc94fe 553 SUPERFAMILY SSF109755 317 528 9.84E-34 T 14-10-2018 TSH58p_27155 1bbc5a1ced198eb356d101375dbc94fe 553 Pfam PF02690 Na+/Pi-cotransporter 10 145 1.7E-28 T 14-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 TSH58p_27155 1bbc5a1ced198eb356d101375dbc94fe 553 Pfam PF02690 Na+/Pi-cotransporter 158 257 9.9E-10 T 14-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 TSH58p_16400 c0a400967247b16c03806d066df5862d 105 SUPERFAMILY SSF103481 6 102 6.54E-20 T 14-10-2018 TSH58p_16400 c0a400967247b16c03806d066df5862d 105 Pfam PF00893 Small Multidrug Resistance protein 2 93 8.4E-28 T 14-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 TSH58p_16400 c0a400967247b16c03806d066df5862d 105 Gene3D G3DSA:1.10.3730.20 1 105 5.5E-32 T 14-10-2018 TSH58p_17975 c8f2ec7ed24511f1f86df88f6152848f 252 Pfam PF09557 Domain of unknown function (DUF2382) 131 241 8.9E-21 T 14-10-2018 IPR019060 Domain of unknown function DUF2382 TSH58p_11300 d51a1368970c9d7d9be285a2b3058022 351 SUPERFAMILY SSF88713 56 224 6.43E-32 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TSH58p_11300 d51a1368970c9d7d9be285a2b3058022 351 Pfam PF01522 Polysaccharide deacetylase 93 219 2.2E-24 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 TSH58p_11300 d51a1368970c9d7d9be285a2b3058022 351 Gene3D G3DSA:3.20.20.370 32 253 6.1E-50 T 14-10-2018 TSH58p_11220 75af9b6b5f96a816c795051a318ddafa 262 Pfam PF00950 ABC 3 transport family 1 257 1.0E-74 T 14-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 TSH58p_11220 75af9b6b5f96a816c795051a318ddafa 262 SUPERFAMILY SSF81345 3 255 3.66E-38 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_11405 c89aabef45fd29b8a23dadbbe2cee3a7 191 Gene3D G3DSA:3.30.300.20 9 114 4.1E-25 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta TSH58p_11405 c89aabef45fd29b8a23dadbbe2cee3a7 191 SUPERFAMILY SSF89919 12 122 3.53E-30 T 14-10-2018 IPR023799 Ribosome-binding factor A domain superfamily TSH58p_11405 c89aabef45fd29b8a23dadbbe2cee3a7 191 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 14 122 2.3E-19 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 TSH58p_11405 c89aabef45fd29b8a23dadbbe2cee3a7 191 Pfam PF02033 Ribosome-binding factor A 15 120 4.3E-27 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 TSH58p_11405 c89aabef45fd29b8a23dadbbe2cee3a7 191 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 14 120 25.334 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 TSH58p_11405 c89aabef45fd29b8a23dadbbe2cee3a7 191 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 18 104 3.0E-21 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 TSH58p_11405 c89aabef45fd29b8a23dadbbe2cee3a7 191 ProSitePatterns PS01319 Ribosome-binding factor A signature. 86 107 - T 14-10-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 TSH58p_18070 0e1bf86d1b3c4d879f46638522392153 330 Pfam PF02719 Polysaccharide biosynthesis protein 7 283 1.3E-105 T 14-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain TSH58p_18070 0e1bf86d1b3c4d879f46638522392153 330 TIGRFAM TIGR03589 PseB: UDP-N-acetylglucosamine 4,6-dehydratase (inverting) 1 324 1.6E-159 T 14-10-2018 IPR020025 UDP-N-acetylglucosamine 4,6-dehydratase (inverting) KEGG: 00520+4.2.1.115|MetaCyc: PWY-6143|MetaCyc: PWY-7330|MetaCyc: PWY-7331|MetaCyc: PWY-7332|MetaCyc: PWY-7719 TSH58p_18070 0e1bf86d1b3c4d879f46638522392153 330 SUPERFAMILY SSF51735 1 275 5.37E-55 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_18070 0e1bf86d1b3c4d879f46638522392153 330 Gene3D G3DSA:3.90.25.30 170 313 3.8E-126 T 14-10-2018 TSH58p_18070 0e1bf86d1b3c4d879f46638522392153 330 Gene3D G3DSA:3.40.50.720 5 309 3.8E-126 T 14-10-2018 TSH58p_09795 695798f129112acdfef108f8441aa2a7 134 Pfam PF06155 Protein of unknown function (DUF971) 20 104 1.2E-27 T 14-10-2018 IPR010376 Gamma-butyrobetaine hydroxylase-like, N-terminal Reactome: R-HSA-71262 TSH58p_09795 695798f129112acdfef108f8441aa2a7 134 Gene3D G3DSA:3.30.2020.30 10 109 7.4E-27 T 14-10-2018 IPR038492 GBBH-like, N-terminal domain superfamily Reactome: R-HSA-71262 TSH58p_01150 60af9c92a4a04a525fe3a80e2500d120 251 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_01150 60af9c92a4a04a525fe3a80e2500d120 251 SUPERFAMILY SSF52540 8 230 2.82E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_01150 60af9c92a4a04a525fe3a80e2500d120 251 Gene3D G3DSA:3.40.50.300 4 248 1.0E-67 T 14-10-2018 TSH58p_01150 60af9c92a4a04a525fe3a80e2500d120 251 Pfam PF00005 ABC transporter 26 169 1.8E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_01150 60af9c92a4a04a525fe3a80e2500d120 251 SMART SM00382 35 218 1.9E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_01150 60af9c92a4a04a525fe3a80e2500d120 251 TIGRFAM TIGR03864 PQQ_ABC_ATP: ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system 11 245 8.1E-104 T 14-10-2018 IPR022467 ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system TSH58p_12200 b0b09f8d219d16ab5f375cab9a57aafa 287 Pfam PF03881 Fructosamine kinase 56 285 4.3E-47 T 14-10-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 TSH58p_12200 b0b09f8d219d16ab5f375cab9a57aafa 287 PIRSF PIRSF006221 6 287 5.2E-50 T 14-10-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 TSH58p_12200 b0b09f8d219d16ab5f375cab9a57aafa 287 Gene3D G3DSA:3.30.200.20 5 88 2.8E-14 T 14-10-2018 TSH58p_12200 b0b09f8d219d16ab5f375cab9a57aafa 287 Gene3D G3DSA:3.90.1200.10 97 287 7.3E-54 T 14-10-2018 TSH58p_12200 b0b09f8d219d16ab5f375cab9a57aafa 287 SUPERFAMILY SSF56112 4 287 9.91E-43 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily TSH58p_23045 9010ea06b251a697790222fa8b74e76a 322 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 320 5.8E-44 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_23045 9010ea06b251a697790222fa8b74e76a 322 Gene3D G3DSA:1.10.3720.10 87 315 1.1E-26 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_23045 9010ea06b251a697790222fa8b74e76a 322 SUPERFAMILY SSF161098 91 308 3.79E-22 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_15655 b92125f30d00a36e1a866f79386fc133 302 Pfam PF08009 CDP-alcohol phosphatidyltransferase 2 214 250 9.0E-14 T 14-10-2018 IPR012616 CDP-alcohol phosphatidyltransferase, C-terminal TSH58p_15655 b92125f30d00a36e1a866f79386fc133 302 Gene3D G3DSA:1.20.120.1760 13 145 3.8E-18 T 14-10-2018 TSH58p_15655 b92125f30d00a36e1a866f79386fc133 302 Pfam PF01066 CDP-alcohol phosphatidyltransferase 32 95 2.4E-15 T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TSH58p_15655 b92125f30d00a36e1a866f79386fc133 302 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 73 95 - T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TSH58p_15655 b92125f30d00a36e1a866f79386fc133 302 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 37 199 1.7E-32 T 14-10-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 TSH58p_06740 a8558b94360786600a4e125791eb179e 373 Pfam PF10503 Esterase PHB depolymerase 52 286 1.2E-21 T 14-10-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 TSH58p_06740 a8558b94360786600a4e125791eb179e 373 Gene3D G3DSA:3.40.50.1820 25 315 1.2E-36 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_06740 a8558b94360786600a4e125791eb179e 373 SUPERFAMILY SSF53474 25 155 1.53E-16 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_06740 a8558b94360786600a4e125791eb179e 373 SUPERFAMILY SSF53474 165 339 6.12E-30 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_07260 813ca1fa29e875c13c0d9aeb3c66f830 533 Pfam PF03288 Poxvirus D5 protein-like 451 502 2.1E-6 T 14-10-2018 IPR004968 DNA primase/nucleoside triphosphatase, C-terminal TSH58p_07260 813ca1fa29e875c13c0d9aeb3c66f830 533 SUPERFAMILY SSF52540 254 427 4.51E-7 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_07260 813ca1fa29e875c13c0d9aeb3c66f830 533 TIGRFAM TIGR01613 primase_Cterm: phage/plasmid primase, P4 family, C-terminal domain 186 498 8.8E-77 T 14-10-2018 IPR006500 DNA primase, phage/plasmid TSH58p_07260 813ca1fa29e875c13c0d9aeb3c66f830 533 Pfam PF08706 D5 N terminal like 57 244 1.1E-22 T 14-10-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal TSH58p_07260 813ca1fa29e875c13c0d9aeb3c66f830 533 SMART SM00885 57 244 1.6E-19 T 14-10-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal TSH58p_10195 8efb380555a23af7e245e12178c67fe3 520 SUPERFAMILY SSF52540 8 254 3.27E-27 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_10195 8efb380555a23af7e245e12178c67fe3 520 Gene3D G3DSA:3.40.50.300 29 249 1.2E-36 T 14-10-2018 TSH58p_10195 8efb380555a23af7e245e12178c67fe3 520 Pfam PF01935 Domain of unknown function DUF87 11 80 1.9E-8 T 14-10-2018 IPR002789 Helicase HerA, central domain TSH58p_10195 8efb380555a23af7e245e12178c67fe3 520 PIRSF PIRSF034081 1 514 1.0E-238 T 14-10-2018 IPR014588 ATPase, Atu1862 type, predicted TSH58p_27840 f420447efb080cc68b2c0dbe322b6e68 179 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 23 151 3.0E-26 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ TSH58p_05605 0851a6d188c56cb01fdd9d4106e8ff2b 503 PRINTS PR00095 Anthranilate synthase component I signature 427 441 1.4E-22 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TSH58p_05605 0851a6d188c56cb01fdd9d4106e8ff2b 503 PRINTS PR00095 Anthranilate synthase component I signature 442 456 1.4E-22 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TSH58p_05605 0851a6d188c56cb01fdd9d4106e8ff2b 503 PRINTS PR00095 Anthranilate synthase component I signature 333 346 1.4E-22 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TSH58p_05605 0851a6d188c56cb01fdd9d4106e8ff2b 503 PRINTS PR00095 Anthranilate synthase component I signature 347 360 1.4E-22 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TSH58p_05605 0851a6d188c56cb01fdd9d4106e8ff2b 503 Pfam PF00425 chorismate binding enzyme 232 485 2.9E-98 T 14-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal TSH58p_05605 0851a6d188c56cb01fdd9d4106e8ff2b 503 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 29 493 9.4E-172 T 14-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TSH58p_05605 0851a6d188c56cb01fdd9d4106e8ff2b 503 Pfam PF04715 Anthranilate synthase component I, N terminal region 29 176 9.3E-30 T 14-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TSH58p_05605 0851a6d188c56cb01fdd9d4106e8ff2b 503 Gene3D G3DSA:3.60.120.10 1 501 1.7E-175 T 14-10-2018 IPR005801 ADC synthase GO:0009058 TSH58p_05605 0851a6d188c56cb01fdd9d4106e8ff2b 503 SUPERFAMILY SSF56322 19 493 3.4E-153 T 14-10-2018 IPR005801 ADC synthase GO:0009058 TSH58p_00290 79c7d87e5424531f2d413f5f796a9722 570 Gene3D G3DSA:2.160.20.10 227 569 1.7E-32 T 14-10-2018 IPR012334 Pectin lyase fold TSH58p_00290 79c7d87e5424531f2d413f5f796a9722 570 Pfam PF16841 Ca-dependent carbohydrate-binding module xylan-binding 76 167 1.3E-31 T 14-10-2018 IPR031768 Carbohydrate binding module, xylan-binding domain MetaCyc: PWY-6717|MetaCyc: PWY-6784 TSH58p_00290 79c7d87e5424531f2d413f5f796a9722 570 Gene3D G3DSA:2.60.60.40 73 189 1.3E-9 T 14-10-2018 TSH58p_00290 79c7d87e5424531f2d413f5f796a9722 570 Pfam PF13229 Right handed beta helix region 308 450 1.2E-10 T 14-10-2018 IPR039448 Right handed beta helix domain TSH58p_00290 79c7d87e5424531f2d413f5f796a9722 570 Pfam PF13229 Right handed beta helix region 453 564 2.4E-6 T 14-10-2018 IPR039448 Right handed beta helix domain TSH58p_00290 79c7d87e5424531f2d413f5f796a9722 570 SMART SM00710 526 549 2200.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_00290 79c7d87e5424531f2d413f5f796a9722 570 SMART SM00710 451 472 1000.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_00290 79c7d87e5424531f2d413f5f796a9722 570 SMART SM00710 341 363 1.4 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_00290 79c7d87e5424531f2d413f5f796a9722 570 SMART SM00710 418 447 8300.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_00290 79c7d87e5424531f2d413f5f796a9722 570 SMART SM00710 317 339 1200.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_00290 79c7d87e5424531f2d413f5f796a9722 570 SMART SM00710 390 413 3100.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_00290 79c7d87e5424531f2d413f5f796a9722 570 SMART SM00710 473 495 47.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_00290 79c7d87e5424531f2d413f5f796a9722 570 SMART SM00710 365 387 380.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_00290 79c7d87e5424531f2d413f5f796a9722 570 SUPERFAMILY SSF51126 226 545 1.65E-36 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor TSH58p_30875 9172eaaf02c75db40bec672772c1fbc7 235 Gene3D G3DSA:1.10.10.10 29 91 8.1E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_30875 9172eaaf02c75db40bec672772c1fbc7 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 31 87 2.6E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_30875 9172eaaf02c75db40bec672772c1fbc7 235 Pfam PF07729 FCD domain 101 222 6.4E-24 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_30875 9172eaaf02c75db40bec672772c1fbc7 235 SMART SM00345 34 90 4.3E-11 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_30875 9172eaaf02c75db40bec672772c1fbc7 235 SUPERFAMILY SSF46785 27 116 1.58E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_30875 9172eaaf02c75db40bec672772c1fbc7 235 Gene3D G3DSA:1.20.120.530 96 234 1.4E-28 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_30875 9172eaaf02c75db40bec672772c1fbc7 235 SUPERFAMILY SSF48008 97 231 7.59E-25 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_30875 9172eaaf02c75db40bec672772c1fbc7 235 SMART SM00895 100 223 3.7E-22 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_28620 1139a8628c6054fed5aca47349abbf55 312 SUPERFAMILY SSF52540 2 240 7.05E-77 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_28620 1139a8628c6054fed5aca47349abbf55 312 SUPERFAMILY SSF54631 267 308 3.67E-6 T 14-10-2018 TSH58p_28620 1139a8628c6054fed5aca47349abbf55 312 Pfam PF00005 ABC transporter 18 163 4.8E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_28620 1139a8628c6054fed5aca47349abbf55 312 Gene3D G3DSA:3.40.50.300 1 266 2.2E-76 T 14-10-2018 TSH58p_28620 1139a8628c6054fed5aca47349abbf55 312 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_28620 1139a8628c6054fed5aca47349abbf55 312 Pfam PF00571 CBS domain 268 307 2.2E-4 T 14-10-2018 IPR000644 CBS domain TSH58p_28620 1139a8628c6054fed5aca47349abbf55 312 SMART SM00382 26 213 1.2E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_05590 cd96c6ef8e027a2e4958bd7db90365a2 110 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 71 7.1E-21 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TSH58p_05590 cd96c6ef8e027a2e4958bd7db90365a2 110 Pfam PF03840 Preprotein translocase SecG subunit 4 70 2.7E-18 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TSH58p_05590 cd96c6ef8e027a2e4958bd7db90365a2 110 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 2.6E-14 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TSH58p_05590 cd96c6ef8e027a2e4958bd7db90365a2 110 PRINTS PR01651 Protein-export SecG membrane protein signature 52 74 2.6E-14 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TSH58p_20895 ab3e2cd60aa9f7f1667cda918c04e606 376 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 144 306 1.7E-20 T 14-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 TSH58p_20895 ab3e2cd60aa9f7f1667cda918c04e606 376 SUPERFAMILY SSF53756 12 368 2.39E-60 T 14-10-2018 TSH58p_20895 ab3e2cd60aa9f7f1667cda918c04e606 376 Gene3D G3DSA:3.40.50.2000 7 176 2.6E-20 T 14-10-2018 TSH58p_20895 ab3e2cd60aa9f7f1667cda918c04e606 376 Gene3D G3DSA:3.40.50.2000 184 369 3.5E-27 T 14-10-2018 TSH58p_26735 0b94408b65e5835feb987e87441d0804 64 Pfam PF04328 Selenoprotein, putative 5 64 7.5E-24 T 14-10-2018 IPR007423 Selenoprotein, putative TSH58p_19415 c04090d057ec635d2c2dc37b7052d66d 389 Gene3D G3DSA:3.90.1300.10 3 389 2.3E-100 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_19415 c04090d057ec635d2c2dc37b7052d66d 389 ProSitePatterns PS00571 Amidases signature. 108 139 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 TSH58p_19415 c04090d057ec635d2c2dc37b7052d66d 389 Pfam PF01425 Amidase 18 381 6.4E-64 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_19415 c04090d057ec635d2c2dc37b7052d66d 389 SUPERFAMILY SSF75304 3 386 4.45E-97 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSH58p_28800 f37136cdeade832c349b518ff7abbf38 364 Gene3D G3DSA:3.90.1150.10 17 354 3.0E-105 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSH58p_28800 f37136cdeade832c349b518ff7abbf38 364 SUPERFAMILY SSF53383 12 362 1.17E-84 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSH58p_28800 f37136cdeade832c349b518ff7abbf38 364 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 9 362 58.395 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 TSH58p_28800 f37136cdeade832c349b518ff7abbf38 364 Pfam PF00155 Aminotransferase class I and II 29 358 6.0E-52 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSH58p_28800 f37136cdeade832c349b518ff7abbf38 364 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 11 360 1.5E-92 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 TSH58p_28800 f37136cdeade832c349b518ff7abbf38 364 Gene3D G3DSA:3.40.640.10 40 264 3.0E-105 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSH58p_21665 835a32c41dcc3c4d9f99b4afb83ad468 134 Pfam PF00072 Response regulator receiver domain 12 123 1.5E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_21665 835a32c41dcc3c4d9f99b4afb83ad468 134 Gene3D G3DSA:3.40.50.12740 9 133 2.2E-34 T 14-10-2018 TSH58p_21665 835a32c41dcc3c4d9f99b4afb83ad468 134 SMART SM00448 10 123 1.2E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_21665 835a32c41dcc3c4d9f99b4afb83ad468 134 SUPERFAMILY SSF52172 10 128 5.55E-35 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_07040 aac73d07984ff5deb0fb94b5f8804a7a 221 Pfam PF04891 NifQ 47 201 7.3E-56 T 14-10-2018 IPR006975 NifQ GO:0009399|GO:0030151 TSH58p_03545 9543ded8f0dbcd3263fdf7d86d62c4f1 114 Pfam PF09956 Uncharacterized conserved protein (DUF2190) 1 106 8.2E-31 T 14-10-2018 IPR011231 Bacteriophage VT1-Sakai, H0018 TSH58p_03545 9543ded8f0dbcd3263fdf7d86d62c4f1 114 PIRSF PIRSF030771 1 108 9.3E-15 T 14-10-2018 IPR011231 Bacteriophage VT1-Sakai, H0018 TSH58p_12390 138a68f416ad2f30af712c5be924db9f 339 Pfam PF00296 Luciferase-like monooxygenase 24 308 4.1E-38 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TSH58p_12390 138a68f416ad2f30af712c5be924db9f 339 Gene3D G3DSA:3.20.20.30 6 334 2.7E-104 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TSH58p_12390 138a68f416ad2f30af712c5be924db9f 339 SUPERFAMILY SSF51679 11 330 5.36E-89 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TSH58p_12390 138a68f416ad2f30af712c5be924db9f 339 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 11 330 7.9E-142 T 14-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 TSH58p_22430 19341c75dccfb809ae9701cf0821ef45 285 Pfam PF05673 Protein of unknown function (DUF815) 33 279 3.2E-106 T 14-10-2018 IPR008533 Domain of unknown function DUF815 TSH58p_22430 19341c75dccfb809ae9701cf0821ef45 285 Gene3D G3DSA:3.40.50.300 60 199 2.4E-6 T 14-10-2018 TSH58p_22430 19341c75dccfb809ae9701cf0821ef45 285 SUPERFAMILY SSF52540 42 246 1.57E-21 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_22385 56eefd8bd7b8ee6e4b64b40bcb94f69b 284 SUPERFAMILY SSF48576 7 283 4.32E-57 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily TSH58p_22385 56eefd8bd7b8ee6e4b64b40bcb94f69b 284 Gene3D G3DSA:1.10.600.10 2 260 2.2E-37 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily TSH58p_22385 56eefd8bd7b8ee6e4b64b40bcb94f69b 284 Pfam PF00494 Squalene/phytoene synthase 15 266 1.5E-53 T 14-10-2018 TSH58p_17415 22bcad9107ea881110e43606989d6cc6 223 SMART SM00479 3 198 5.0E-12 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TSH58p_17415 22bcad9107ea881110e43606989d6cc6 223 Gene3D G3DSA:3.30.420.10 3 194 1.8E-33 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TSH58p_17415 22bcad9107ea881110e43606989d6cc6 223 Pfam PF00929 Exonuclease 5 189 4.7E-13 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TSH58p_17415 22bcad9107ea881110e43606989d6cc6 223 SUPERFAMILY SSF53098 5 195 6.17E-36 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily TSH58p_31135 1a1c51687865123c46167a7b7118f1c5 725 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 620 686 9.7E-12 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_31135 1a1c51687865123c46167a7b7118f1c5 725 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 274 339 4.7E-18 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_31135 1a1c51687865123c46167a7b7118f1c5 725 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 272 359 8.4E-23 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_31135 1a1c51687865123c46167a7b7118f1c5 725 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 618 705 2.8E-15 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSH58p_31135 1a1c51687865123c46167a7b7118f1c5 725 SUPERFAMILY SSF52540 44 293 3.13E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_31135 1a1c51687865123c46167a7b7118f1c5 725 Pfam PF00005 ABC transporter 417 567 3.0E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_31135 1a1c51687865123c46167a7b7118f1c5 725 ProSitePatterns PS00211 ABC transporters family signature. 540 554 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_31135 1a1c51687865123c46167a7b7118f1c5 725 Gene3D G3DSA:3.40.50.300 388 716 6.3E-85 T 14-10-2018 TSH58p_31135 1a1c51687865123c46167a7b7118f1c5 725 Gene3D G3DSA:3.40.50.300 41 367 1.6E-92 T 14-10-2018 TSH58p_31135 1a1c51687865123c46167a7b7118f1c5 725 ProSitePatterns PS00211 ABC transporters family signature. 195 209 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_31135 1a1c51687865123c46167a7b7118f1c5 725 Pfam PF00005 ABC transporter 65 222 4.3E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_31135 1a1c51687865123c46167a7b7118f1c5 725 SUPERFAMILY SSF52540 389 638 2.77E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_31135 1a1c51687865123c46167a7b7118f1c5 725 SMART SM00382 425 617 1.0E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_31135 1a1c51687865123c46167a7b7118f1c5 725 SMART SM00382 73 271 1.8E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_24615 e20eb2fbe6e4eb4fed20a06a427aaafb 420 SUPERFAMILY SSF161098 192 404 4.19E-43 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_24615 e20eb2fbe6e4eb4fed20a06a427aaafb 420 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 232 405 5.3E-8 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_24615 e20eb2fbe6e4eb4fed20a06a427aaafb 420 Gene3D G3DSA:1.10.3720.10 163 418 9.7E-48 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_03955 444a04b50d5a1f7f8ade89a2c578b7f3 214 Pfam PF09976 Tetratricopeptide repeat-like domain 21 197 8.2E-6 T 14-10-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 TSH58p_28880 777652e303e7ea2a8406027e94fab2d2 197 SMART SM01207 8 183 8.8E-82 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 TSH58p_28880 777652e303e7ea2a8406027e94fab2d2 197 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 4 191 7.3E-52 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 TSH58p_28880 777652e303e7ea2a8406027e94fab2d2 197 Pfam PF02660 Glycerol-3-phosphate acyltransferase 9 182 4.0E-48 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 TSH58p_28880 777652e303e7ea2a8406027e94fab2d2 197 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 5 191 20.104 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 TSH58p_13555 3e90265e4c66b9c2788eecda5d65fb93 364 Pfam PF13649 Methyltransferase domain 199 294 2.8E-18 T 14-10-2018 TSH58p_13555 3e90265e4c66b9c2788eecda5d65fb93 364 Gene3D G3DSA:3.40.50.150 139 357 2.6E-30 T 14-10-2018 TSH58p_13555 3e90265e4c66b9c2788eecda5d65fb93 364 SUPERFAMILY SSF53335 157 349 2.46E-33 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_21145 c2fd382968ecfc6dc42e0986901fdc63 300 Gene3D G3DSA:1.10.3720.10 85 295 4.8E-27 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_21145 c2fd382968ecfc6dc42e0986901fdc63 300 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 16 58 4.5E-8 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TSH58p_21145 c2fd382968ecfc6dc42e0986901fdc63 300 SUPERFAMILY SSF161098 93 284 2.62E-28 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_21145 c2fd382968ecfc6dc42e0986901fdc63 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 299 7.4E-31 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_24355 31b3752115c66f82289d7f930b513e07 230 Pfam PF06055 Exopolysaccharide synthesis, ExoD 36 211 1.5E-54 T 14-10-2018 IPR010331 Exopolysaccharide synthesis, ExoD TSH58p_24355 31b3752115c66f82289d7f930b513e07 230 PIRSF PIRSF033239 23 226 1.2E-54 T 14-10-2018 IPR010331 Exopolysaccharide synthesis, ExoD TSH58p_27270 172b6026f02c9fc5ee46357df16a32b4 446 Pfam PF10679 Protein of unknown function (DUF2491) 253 443 2.8E-18 T 14-10-2018 IPR019621 Protein of unknown function DUF2491 TSH58p_18505 588389d601b8a46f1f6fe2b2673492d6 246 Gene3D G3DSA:3.90.550.10 4 124 5.8E-10 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_18505 588389d601b8a46f1f6fe2b2673492d6 246 Pfam PF00535 Glycosyl transferase family 2 23 97 8.7E-9 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_18505 588389d601b8a46f1f6fe2b2673492d6 246 SUPERFAMILY SSF53448 22 91 3.75E-10 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_24280 b4c339a139142a0e951a25d114389341 219 SUPERFAMILY SSF52833 11 200 5.23E-35 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_24280 b4c339a139142a0e951a25d114389341 219 Pfam PF08534 Redoxin 63 188 2.4E-17 T 14-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 TSH58p_24280 b4c339a139142a0e951a25d114389341 219 Gene3D G3DSA:3.40.30.10 36 203 3.2E-40 T 14-10-2018 TSH58p_24280 b4c339a139142a0e951a25d114389341 219 ProSitePatterns PS00194 Thioredoxin family active site. 89 107 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 TSH58p_10105 287a515c1209dd462f2010543255b5bc 75 Pfam PF13441 YMGG-like Gly-zipper 27 69 3.6E-7 T 14-10-2018 IPR027367 YMGG-like Gly-zipper TSH58p_20375 f045d71362081658072948429ab2e026 226 Gene3D G3DSA:1.10.1760.20 1 213 2.5E-7 T 14-10-2018 TSH58p_20375 f045d71362081658072948429ab2e026 226 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 211 4.7E-15 T 14-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 TSH58p_08260 2540d47b3e5c0ba6283dcfd89d10da89 240 SUPERFAMILY SSF52540 1 234 4.13E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_08260 2540d47b3e5c0ba6283dcfd89d10da89 240 Pfam PF00005 ABC transporter 18 162 6.2E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_08260 2540d47b3e5c0ba6283dcfd89d10da89 240 SMART SM00382 26 211 7.5E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_08260 2540d47b3e5c0ba6283dcfd89d10da89 240 Gene3D G3DSA:3.40.50.300 1 235 7.5E-56 T 14-10-2018 TSH58p_08260 2540d47b3e5c0ba6283dcfd89d10da89 240 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 212 233 1.8E-9 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSH58p_10275 440123bb3e074e34446cd2e70e92170b 103 Pfam PF09650 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) 6 95 1.4E-17 T 14-10-2018 IPR013433 Putative polyhydroxyalkanoic acid system protein TSH58p_09405 d1efba659302bdc5bd4e97e32533696b 107 Pfam PF00893 Small Multidrug Resistance protein 1 93 1.4E-29 T 14-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 TSH58p_09405 d1efba659302bdc5bd4e97e32533696b 107 Gene3D G3DSA:1.10.3730.20 1 105 3.2E-37 T 14-10-2018 TSH58p_09405 d1efba659302bdc5bd4e97e32533696b 107 SUPERFAMILY SSF103481 5 104 3.92E-20 T 14-10-2018 TSH58p_11500 7be7ba80b7e0f6a38740e847d10caf3b 602 Gene3D G3DSA:3.40.190.10 29 597 7.8E-235 T 14-10-2018 TSH58p_11500 7be7ba80b7e0f6a38740e847d10caf3b 602 PIRSF PIRSF002741 2 600 4.8E-96 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TSH58p_11500 7be7ba80b7e0f6a38740e847d10caf3b 602 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 100 514 1.4E-77 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain TSH58p_11500 7be7ba80b7e0f6a38740e847d10caf3b 602 Gene3D G3DSA:3.10.105.10 317 577 7.8E-235 T 14-10-2018 TSH58p_11500 7be7ba80b7e0f6a38740e847d10caf3b 602 SUPERFAMILY SSF53850 51 598 1.99E-120 T 14-10-2018 TSH58p_13945 21ecd7cb5c011878c05b4549301dddf2 175 Pfam PF02600 Disulfide bond formation protein DsbB 11 159 4.4E-35 T 14-10-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 TSH58p_13945 21ecd7cb5c011878c05b4549301dddf2 175 SUPERFAMILY SSF158442 16 160 3.14E-31 T 14-10-2018 IPR023380 DsbB-like superfamily TSH58p_13945 21ecd7cb5c011878c05b4549301dddf2 175 Gene3D G3DSA:1.20.1550.10 6 174 1.9E-25 T 14-10-2018 IPR023380 DsbB-like superfamily TSH58p_13945 21ecd7cb5c011878c05b4549301dddf2 175 PIRSF PIRSF033913 6 166 1.1E-33 T 14-10-2018 IPR024199 Uncharacterised conserved protein, DsbB-like TSH58p_02990 95b3f9a2cdd312e12a781d5d4ff0d0a4 255 SUPERFAMILY SSF52266 74 238 2.28E-14 T 14-10-2018 TSH58p_02990 95b3f9a2cdd312e12a781d5d4ff0d0a4 255 Gene3D G3DSA:3.40.50.1110 67 242 1.5E-15 T 14-10-2018 IPR036514 SGNH hydrolase superfamily TSH58p_09255 7ff7d370112597d95bf892e18917f40f 145 SUPERFAMILY SSF50346 54 137 2.35E-9 T 14-10-2018 IPR011033 PRC-barrel-like superfamily TSH58p_09255 7ff7d370112597d95bf892e18917f40f 145 Gene3D G3DSA:2.30.30.240 30 129 3.3E-13 T 14-10-2018 TSH58p_09255 7ff7d370112597d95bf892e18917f40f 145 Pfam PF05239 PRC-barrel domain 55 123 1.4E-6 T 14-10-2018 IPR027275 PRC-barrel domain TSH58p_31315 c6f486f01da6518cce472a2c32d9b2ec 401 Pfam PF02687 FtsX-like permease family 307 394 1.0E-11 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 TSH58p_31315 c6f486f01da6518cce472a2c32d9b2ec 401 Pfam PF12704 MacB-like periplasmic core domain 20 240 1.1E-44 T 14-10-2018 IPR025857 MacB-like periplasmic core domain TSH58p_13430 f9859ab07624eba51c31c0791bf37978 80 Pfam PF13711 Domain of unknown function (DUF4160) 9 73 7.9E-20 T 14-10-2018 IPR025427 Protein of unknown function DUF4160 TSH58p_14850 b670e2a84d95c41c8fa2edb750a2f74f 267 SUPERFAMILY SSF161098 69 251 8.63E-31 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_14850 b670e2a84d95c41c8fa2edb750a2f74f 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 263 5.0E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_14850 b670e2a84d95c41c8fa2edb750a2f74f 267 Gene3D G3DSA:1.10.3720.10 69 265 2.2E-22 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_26610 c28b94a224d1982b930d4c57308a53da 242 Gene3D G3DSA:1.25.40.590 34 174 5.7E-6 T 14-10-2018 IPR038522 Type IV / VI secretion system, DotU superfamily TSH58p_09690 4e75385fbde7007681291d37d706b43e 446 Pfam PF07044 Protein of unknown function (DUF1329) 84 439 5.6E-110 T 14-10-2018 IPR010752 Protein of unknown function DUF1329 TSH58p_23165 78255f0c472d725be28160a32f787dd9 692 Gene3D G3DSA:3.30.565.10 193 373 5.0E-15 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_23165 78255f0c472d725be28160a32f787dd9 692 SUPERFAMILY SSF55874 189 310 6.55E-14 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSH58p_23165 78255f0c472d725be28160a32f787dd9 692 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 204 314 8.9E-25 T 14-10-2018 TSH58p_31400 1c3cfc9691c90ab16a8671137152d0fb 333 Pfam PF04773 FecR protein 127 218 5.2E-20 T 14-10-2018 IPR006860 FecR protein TSH58p_31400 1c3cfc9691c90ab16a8671137152d0fb 333 Pfam PF16344 Domain of unknown function (DUF4974) 231 304 6.9E-8 T 14-10-2018 IPR032508 Protein FecR, C-terminal TSH58p_31400 1c3cfc9691c90ab16a8671137152d0fb 333 PIRSF PIRSF018266 3 332 1.5E-80 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component TSH58p_31400 1c3cfc9691c90ab16a8671137152d0fb 333 Gene3D G3DSA:2.60.120.1440 121 251 5.1E-25 T 14-10-2018 TSH58p_31400 1c3cfc9691c90ab16a8671137152d0fb 333 Gene3D G3DSA:3.55.50.30 257 303 2.8E-5 T 14-10-2018 TSH58p_31400 1c3cfc9691c90ab16a8671137152d0fb 333 Pfam PF16220 Domain of unknown function (DUF4880) 12 54 3.9E-11 T 14-10-2018 IPR032623 FecR, N-terminal TSH58p_30395 7c7b80a205cb941f9787b009afd12a08 435 Pfam PF04143 Sulphur transport 92 423 2.6E-59 T 14-10-2018 IPR007272 Sulphur transport domain TSH58p_18500 942b88c37927ef1f61e559c1183764a7 458 Pfam PF13524 Glycosyl transferases group 1 127 201 1.0E-8 T 14-10-2018 TSH58p_18500 942b88c37927ef1f61e559c1183764a7 458 Gene3D G3DSA:3.40.50.2000 40 192 3.9E-15 T 14-10-2018 TSH58p_18500 942b88c37927ef1f61e559c1183764a7 458 SUPERFAMILY SSF53756 16 207 7.85E-19 T 14-10-2018 TSH58p_18380 7fe438595c56aaffdecf8b07807b49ba 288 SUPERFAMILY SSF53448 1 286 9.66E-93 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_18380 7fe438595c56aaffdecf8b07807b49ba 288 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 2.3E-150 T 14-10-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 TSH58p_18380 7fe438595c56aaffdecf8b07807b49ba 288 Pfam PF00483 Nucleotidyl transferase 2 238 4.1E-69 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TSH58p_18380 7fe438595c56aaffdecf8b07807b49ba 288 Gene3D G3DSA:3.90.550.10 1 288 2.6E-86 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_12815 621836d5ddf5bd01adb25aa521c3f89b 170 Gene3D G3DSA:2.60.40.1880 36 170 5.1E-7 T 14-10-2018 IPR038696 Invasion protein B superfamily TSH58p_12815 621836d5ddf5bd01adb25aa521c3f89b 170 Pfam PF06776 Invasion associated locus B (IalB) protein 38 165 3.2E-6 T 14-10-2018 IPR010642 Invasion protein B TSH58p_10550 375335ee7e93d658b54129b75183c053 603 Pfam PF00332 Glycosyl hydrolases family 17 226 303 4.9E-7 T 14-10-2018 IPR000490 Glycoside hydrolase family 17 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.39 TSH58p_10550 375335ee7e93d658b54129b75183c053 603 Gene3D G3DSA:3.20.20.80 49 309 4.7E-14 T 14-10-2018 TSH58p_10550 375335ee7e93d658b54129b75183c053 603 SUPERFAMILY SSF51445 38 303 1.59E-54 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily TSH58p_12605 c95c4c6804a4776bba1811d8179403d0 277 SUPERFAMILY SSF69593 15 218 1.7E-10 T 14-10-2018 TSH58p_12605 c95c4c6804a4776bba1811d8179403d0 277 SMART SM00563 57 175 3.0E-8 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TSH58p_12605 c95c4c6804a4776bba1811d8179403d0 277 Pfam PF01553 Acyltransferase 51 172 1.1E-6 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TSH58p_12540 328b30e93d46cebf9a03603cdf6fb33a 208 Pfam PF02659 Putative manganese efflux pump 48 202 9.9E-49 T 14-10-2018 IPR003810 Putative manganese efflux pump TSH58p_12540 328b30e93d46cebf9a03603cdf6fb33a 208 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 17 205 23.145 T 14-10-2018 IPR022929 Putative manganese efflux pump MntP TSH58p_31540 fe8122d2ae29897018a17d62ad828c13 257 Gene3D G3DSA:1.10.3720.10 49 246 4.0E-22 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_31540 fe8122d2ae29897018a17d62ad828c13 257 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 245 1.4E-21 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_31540 fe8122d2ae29897018a17d62ad828c13 257 SUPERFAMILY SSF161098 50 233 6.93E-26 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_19145 562d3bcf5ee15c79a59b53ce27b79951 175 SUPERFAMILY SSF140566 48 89 5.75E-5 T 14-10-2018 IPR036679 FlgN-like superfamily GO:0005515|GO:0044780 TSH58p_28355 58688c9a985607a8b0b42c6dfc14c869 222 Pfam PF00551 Formyl transferase 10 190 5.6E-59 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TSH58p_28355 58688c9a985607a8b0b42c6dfc14c869 222 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 10 200 1.2E-73 T 14-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 TSH58p_28355 58688c9a985607a8b0b42c6dfc14c869 222 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 10 196 32.16 T 14-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 TSH58p_28355 58688c9a985607a8b0b42c6dfc14c869 222 SUPERFAMILY SSF53328 9 205 7.2E-65 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TSH58p_28355 58688c9a985607a8b0b42c6dfc14c869 222 Gene3D G3DSA:3.40.50.170 2 214 6.1E-82 T 14-10-2018 TSH58p_14625 b4e19e55b56eb720b297707abd3ac422 487 SUPERFAMILY SSF90123 342 435 3.92E-5 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_14625 b4e19e55b56eb720b297707abd3ac422 487 Pfam PF00350 Dynamin family 61 214 7.1E-12 T 14-10-2018 IPR022812 Dynamin superfamily TSH58p_14625 b4e19e55b56eb720b297707abd3ac422 487 Gene3D G3DSA:3.40.50.300 61 303 1.1E-33 T 14-10-2018 TSH58p_14625 b4e19e55b56eb720b297707abd3ac422 487 SUPERFAMILY SSF52540 58 247 4.71E-16 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_10840 ec658d761fcdd9e1225be1b33d45ba47 399 Pfam PF00534 Glycosyl transferases group 1 272 371 2.3E-26 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 TSH58p_10840 ec658d761fcdd9e1225be1b33d45ba47 399 Gene3D G3DSA:3.40.50.2000 169 377 1.4E-46 T 14-10-2018 TSH58p_10840 ec658d761fcdd9e1225be1b33d45ba47 399 Gene3D G3DSA:3.40.50.2000 22 168 1.4E-46 T 14-10-2018 TSH58p_10840 ec658d761fcdd9e1225be1b33d45ba47 399 SUPERFAMILY SSF53756 2 387 7.18E-54 T 14-10-2018 TSH58p_10255 a592b8cde2b225b1f1b42c44dc67e9e0 133 Pfam PF04024 PspC domain 14 70 9.3E-18 T 14-10-2018 IPR007168 Phage shock protein, PspC, N-terminal TSH58p_10255 a592b8cde2b225b1f1b42c44dc67e9e0 133 TIGRFAM TIGR02978 phageshock_pspC: phage shock protein C 13 131 8.0E-33 T 14-10-2018 IPR014320 Phage shock protein, PspC TSH58p_27300 e77200acdce29a0045e9647b1b52f64c 647 Pfam PF01433 Peptidase family M1 domain 267 410 9.3E-10 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TSH58p_27300 e77200acdce29a0045e9647b1b52f64c 647 SUPERFAMILY SSF55486 190 420 4.91E-39 T 14-10-2018 TSH58p_27300 e77200acdce29a0045e9647b1b52f64c 647 Gene3D G3DSA:1.10.390.60 183 415 8.0E-28 T 14-10-2018 TSH58p_04115 c27b59bbef67d71f649e74cf43779a35 358 Gene3D G3DSA:3.90.226.40 6 357 2.0E-132 T 14-10-2018 TSH58p_04115 c27b59bbef67d71f649e74cf43779a35 358 SUPERFAMILY SSF52096 9 329 4.44E-69 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_04115 c27b59bbef67d71f649e74cf43779a35 358 Pfam PF16113 Enoyl-CoA hydratase/isomerase 20 346 1.0E-129 T 14-10-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 TSH58p_19110 52a77a72f72726b5e30f60a34af1591d 107 Gene3D G3DSA:1.10.1660.10 2 57 4.3E-7 T 14-10-2018 TSH58p_27595 67a2b711eedf8daa3fe9f8b7bf3ed78f 257 Pfam PF02108 Flagellar assembly protein FliH 107 249 1.7E-33 T 14-10-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE TSH58p_27245 1d3b770bdefb663275a047bd074d0e62 114 Pfam PF09633 Protein of unknown function (DUF2023) 5 102 2.6E-41 T 14-10-2018 IPR018594 Domain of unknown function DUF2023 TSH58p_27245 1d3b770bdefb663275a047bd074d0e62 114 SUPERFAMILY SSF160448 4 103 2.62E-39 T 14-10-2018 IPR036780 PG1857-like superfamily TSH58p_27245 1d3b770bdefb663275a047bd074d0e62 114 Gene3D G3DSA:3.30.2190.10 1 107 2.3E-41 T 14-10-2018 IPR036780 PG1857-like superfamily TSH58p_02395 03b0a86d6f14bc3692b6b13fd9324bf6 312 Gene3D G3DSA:1.10.3720.10 82 270 2.8E-35 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_02395 03b0a86d6f14bc3692b6b13fd9324bf6 312 SUPERFAMILY SSF161098 84 267 4.06E-42 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_02395 03b0a86d6f14bc3692b6b13fd9324bf6 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 266 4.4E-28 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_27815 8ab881c97ba1ef53566f77db37c65ecb 208 PRINTS PR01011 Glutathione peroxidase family signature 100 116 1.1E-14 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 TSH58p_27815 8ab881c97ba1ef53566f77db37c65ecb 208 PRINTS PR01011 Glutathione peroxidase family signature 65 82 1.1E-14 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 TSH58p_27815 8ab881c97ba1ef53566f77db37c65ecb 208 PRINTS PR01011 Glutathione peroxidase family signature 163 172 1.1E-14 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 TSH58p_27815 8ab881c97ba1ef53566f77db37c65ecb 208 ProSitePatterns PS00460 Glutathione peroxidases active site. 67 82 - T 14-10-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 TSH58p_27815 8ab881c97ba1ef53566f77db37c65ecb 208 SUPERFAMILY SSF52833 50 201 1.03E-44 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_27815 8ab881c97ba1ef53566f77db37c65ecb 208 Pfam PF00255 Glutathione peroxidase 55 152 8.4E-29 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 TSH58p_27815 8ab881c97ba1ef53566f77db37c65ecb 208 Gene3D G3DSA:3.40.30.10 39 205 1.6E-44 T 14-10-2018 TSH58p_27815 8ab881c97ba1ef53566f77db37c65ecb 208 PIRSF PIRSF000303 21 205 1.2E-48 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 TSH58p_11975 ba2d5fbf25c108820154444a888a87aa 412 Pfam PF08242 Methyltransferase domain 58 158 2.0E-13 T 14-10-2018 IPR013217 Methyltransferase type 12 TSH58p_11975 ba2d5fbf25c108820154444a888a87aa 412 SUPERFAMILY SSF53335 46 271 3.53E-28 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_08665 a41f35cde009b5dc0e34ee4987686245 262 Gene3D G3DSA:3.40.980.10 14 177 5.7E-52 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSH58p_08665 a41f35cde009b5dc0e34ee4987686245 262 Pfam PF00994 Probable molybdopterin binding domain 17 176 2.1E-33 T 14-10-2018 IPR001453 MoaB/Mog domain TSH58p_08665 a41f35cde009b5dc0e34ee4987686245 262 SUPERFAMILY SSF53218 13 200 1.1E-38 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSH58p_08665 a41f35cde009b5dc0e34ee4987686245 262 SMART SM00852 17 178 1.6E-30 T 14-10-2018 IPR001453 MoaB/Mog domain TSH58p_18710 34671d4f350ccd5e3fa112778fbbdca7 232 Pfam PF07298 NnrU protein 10 229 1.2E-55 T 14-10-2018 IPR009915 NnrU domain TSH58p_04105 65f862d5d3af314a6374c9105a1c2bcf 282 Pfam PF00149 Calcineurin-like phosphoesterase 3 192 1.3E-13 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TSH58p_04105 65f862d5d3af314a6374c9105a1c2bcf 282 SUPERFAMILY SSF56300 3 243 1.49E-42 T 14-10-2018 TSH58p_04105 65f862d5d3af314a6374c9105a1c2bcf 282 Gene3D G3DSA:3.60.21.10 1 270 1.1E-32 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like TSH58p_11970 e3d22d4fc2c0578bd2bf7a2ed9cd4937 438 Pfam PF00909 Ammonium Transporter Family 45 436 1.3E-124 T 14-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 TSH58p_11970 e3d22d4fc2c0578bd2bf7a2ed9cd4937 438 ProSitePatterns PS01219 Ammonium transporters signature. 195 220 - T 14-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 TSH58p_11970 e3d22d4fc2c0578bd2bf7a2ed9cd4937 438 Gene3D G3DSA:1.10.3430.10 20 438 9.1E-146 T 14-10-2018 IPR029020 Ammonium/urea transporter TSH58p_11970 e3d22d4fc2c0578bd2bf7a2ed9cd4937 438 SUPERFAMILY SSF111352 39 419 7.98E-135 T 14-10-2018 TSH58p_11970 e3d22d4fc2c0578bd2bf7a2ed9cd4937 438 TIGRFAM TIGR00836 amt: ammonium transporter 43 436 1.9E-141 T 14-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 TSH58p_05385 eca7fda8baf829ad32558f17674b9503 629 SMART SM00448 504 617 4.1E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_05385 eca7fda8baf829ad32558f17674b9503 629 Pfam PF00072 Response regulator receiver domain 506 617 5.3E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_05385 eca7fda8baf829ad32558f17674b9503 629 Gene3D G3DSA:3.40.50.12740 503 627 9.2E-31 T 14-10-2018 TSH58p_05385 eca7fda8baf829ad32558f17674b9503 629 SUPERFAMILY SSF52172 504 622 4.84E-33 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_00390 b644851a9b744c4c042ee38d27dea792 231 Gene3D G3DSA:1.20.120.530 85 220 1.4E-30 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_00390 b644851a9b744c4c042ee38d27dea792 231 SUPERFAMILY SSF48008 87 218 4.97E-26 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_00390 b644851a9b744c4c042ee38d27dea792 231 Gene3D G3DSA:1.10.10.10 4 80 9.7E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_00390 b644851a9b744c4c042ee38d27dea792 231 SUPERFAMILY SSF46785 13 105 2.47E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_00390 b644851a9b744c4c042ee38d27dea792 231 Pfam PF07729 FCD domain 89 211 4.0E-28 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_00390 b644851a9b744c4c042ee38d27dea792 231 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 79 1.1E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_00390 b644851a9b744c4c042ee38d27dea792 231 SMART SM00895 89 213 1.4E-23 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_00390 b644851a9b744c4c042ee38d27dea792 231 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 5.7E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_00390 b644851a9b744c4c042ee38d27dea792 231 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 5.7E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_00390 b644851a9b744c4c042ee38d27dea792 231 SMART SM00345 21 79 8.3E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_14230 d0537f380baf126de32751c2e896d102 372 Gene3D G3DSA:1.10.287.500 145 192 9.7E-6 T 14-10-2018 TSH58p_14230 d0537f380baf126de32751c2e896d102 372 Pfam PF04344 Chemotaxis phosphatase, CheZ 152 240 7.2E-8 T 14-10-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 TSH58p_14230 d0537f380baf126de32751c2e896d102 372 SUPERFAMILY SSF75708 71 240 1.28E-38 T 14-10-2018 TSH58p_08265 1774c01a0b56487acf9133f7b9a5bfaa 350 Pfam PF02653 Branched-chain amino acid transport system / permease component 44 309 6.4E-40 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_25355 e87caec8a8eccf12dc28ab69fbddc0a1 260 Pfam PF08849 Putative inner membrane protein (DUF1819) 19 190 8.4E-6 T 14-10-2018 IPR014948 Protein of unknown function DUF1819, putative inner membrane TSH58p_20750 eb8af36b5c6b230da0911de6ee71a129 394 SUPERFAMILY SSF46626 190 385 2.51E-33 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_20750 eb8af36b5c6b230da0911de6ee71a129 394 Gene3D G3DSA:1.10.760.10 202 394 5.7E-70 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_20750 eb8af36b5c6b230da0911de6ee71a129 394 SUPERFAMILY SSF46626 31 198 3.87E-35 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_20750 eb8af36b5c6b230da0911de6ee71a129 394 Pfam PF03150 Di-haem cytochrome c peroxidase 45 214 2.4E-44 T 14-10-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 TSH58p_20750 eb8af36b5c6b230da0911de6ee71a129 394 Gene3D G3DSA:1.10.760.10 38 201 4.3E-58 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSH58p_20750 eb8af36b5c6b230da0911de6ee71a129 394 PIRSF PIRSF000294 19 391 1.5E-51 T 14-10-2018 IPR026259 Di-c-type haem protein, MauG/cytochrome c peroxidase GO:0016491|GO:0020037|GO:0055114 TSH58p_00655 62cc60ca8494e711ce62697357478aed 657 SUPERFAMILY SSF58104 371 654 9.59E-40 T 14-10-2018 TSH58p_00655 62cc60ca8494e711ce62697357478aed 657 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 100 129 4.5E-5 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_00655 62cc60ca8494e711ce62697357478aed 657 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 213 242 4.5E-5 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TSH58p_00655 62cc60ca8494e711ce62697357478aed 657 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 163 317 6.2E-28 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_00655 62cc60ca8494e711ce62697357478aed 657 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 463 619 4.8E-22 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_00655 62cc60ca8494e711ce62697357478aed 657 Gene3D G3DSA:1.10.287.950 359 656 4.4E-38 T 14-10-2018 TSH58p_00655 62cc60ca8494e711ce62697357478aed 657 Gene3D G3DSA:1.10.287.950 43 358 1.7E-46 T 14-10-2018 TSH58p_00655 62cc60ca8494e711ce62697357478aed 657 SMART SM00283 65 354 7.6E-29 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_00655 62cc60ca8494e711ce62697357478aed 657 SMART SM00283 372 654 1.1E-7 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TSH58p_00655 62cc60ca8494e711ce62697357478aed 657 SUPERFAMILY SSF58104 72 357 1.74E-45 T 14-10-2018 TSH58p_29625 3811d955af3a58685adbd945c7067e21 63 Pfam PF11154 Protein of unknown function (DUF2934) 2 36 2.9E-15 T 14-10-2018 IPR021327 Protein of unknown function DUF2934 TSH58p_11715 07d5c075dc834db974a43509567ee9e4 262 Gene3D G3DSA:3.40.50.720 3 256 8.9E-88 T 14-10-2018 TSH58p_11715 07d5c075dc834db974a43509567ee9e4 262 Pfam PF00899 ThiF family 11 249 5.7E-63 T 14-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 TSH58p_11715 07d5c075dc834db974a43509567ee9e4 262 SUPERFAMILY SSF69572 2 255 5.36E-90 T 14-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 TSH58p_16900 992ada924dd044063e58c31d96c317fa 195 Pfam PF05951 Bacterial protein of unknown function (DUF882) 46 193 1.7E-57 T 14-10-2018 IPR010275 Protein of unknown function DUF882 TSH58p_16900 992ada924dd044063e58c31d96c317fa 195 SUPERFAMILY SSF55166 76 194 1.37E-33 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSH58p_16900 992ada924dd044063e58c31d96c317fa 195 Gene3D G3DSA:3.30.1380.10 77 195 4.8E-13 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSH58p_14915 8833cc28bc495c332c097977bf4a09da 430 Gene3D G3DSA:3.20.20.120 153 386 2.1E-20 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TSH58p_14915 8833cc28bc495c332c097977bf4a09da 430 SUPERFAMILY SSF51604 161 331 8.93E-13 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TSH58p_10655 c7469e975ae4fd879a383561561bdf18 277 Pfam PF13371 Tetratricopeptide repeat 198 269 1.5E-15 T 14-10-2018 TSH58p_10655 c7469e975ae4fd879a383561561bdf18 277 Gene3D G3DSA:1.25.40.10 173 276 4.3E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_10655 c7469e975ae4fd879a383561561bdf18 277 Pfam PF13369 Transglutaminase-like superfamily 43 195 9.9E-40 T 14-10-2018 IPR032698 Protein SirB1, N-terminal Reactome: R-HSA-8951664|Reactome: R-HSA-983168 TSH58p_32010 097f6ecb39dd3deb51fe57776440263e 208 SUPERFAMILY SSF143555 33 193 4.45E-6 T 14-10-2018 TSH58p_32010 097f6ecb39dd3deb51fe57776440263e 208 Pfam PF02663 FmdE, Molybdenum formylmethanofuran dehydrogenase operon 43 189 3.7E-6 T 14-10-2018 IPR003814 Formylmethanofuran dehydrogenase, subunit E domain TSH58p_17830 9b94f3ca908b6601af06fccf67860266 853 Pfam PF00535 Glycosyl transferase family 2 183 362 1.8E-17 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSH58p_17830 9b94f3ca908b6601af06fccf67860266 853 SUPERFAMILY SSF53756 468 826 4.52E-19 T 14-10-2018 TSH58p_17830 9b94f3ca908b6601af06fccf67860266 853 Gene3D G3DSA:3.40.50.2000 678 833 8.5E-8 T 14-10-2018 TSH58p_17830 9b94f3ca908b6601af06fccf67860266 853 SUPERFAMILY SSF53448 180 410 5.13E-38 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_17830 9b94f3ca908b6601af06fccf67860266 853 Gene3D G3DSA:3.40.50.2000 632 677 8.5E-8 T 14-10-2018 TSH58p_17830 9b94f3ca908b6601af06fccf67860266 853 Gene3D G3DSA:3.90.550.10 175 418 9.0E-31 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_32115 e9a50d3801b5f92fc2941f99ff5378a7 510 Pfam PF00665 Integrase core domain 119 252 1.5E-8 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 TSH58p_32115 e9a50d3801b5f92fc2941f99ff5378a7 510 Gene3D G3DSA:3.30.420.10 108 322 2.9E-21 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TSH58p_32115 e9a50d3801b5f92fc2941f99ff5378a7 510 SUPERFAMILY SSF53098 114 261 1.11E-10 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily TSH58p_14040 a8eb06267b359865f78e28b4d6846626 101 Gene3D G3DSA:3.30.750.24 1 101 2.2E-20 T 14-10-2018 IPR036513 STAS domain superfamily TSH58p_14040 a8eb06267b359865f78e28b4d6846626 101 SUPERFAMILY SSF52091 1 100 9.22E-21 T 14-10-2018 IPR036513 STAS domain superfamily TSH58p_14040 a8eb06267b359865f78e28b4d6846626 101 Pfam PF13466 STAS domain 14 90 4.5E-14 T 14-10-2018 IPR002645 STAS domain TSH58p_32550 206a57bc594a42b9e802192b9415bd9e 223 Pfam PF03737 Aldolase/RraA 26 172 1.5E-40 T 14-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein TSH58p_32550 206a57bc594a42b9e802192b9415bd9e 223 Gene3D G3DSA:3.50.30.40 23 174 8.9E-56 T 14-10-2018 TSH58p_32550 206a57bc594a42b9e802192b9415bd9e 223 TIGRFAM TIGR02798 ligK_PcmE: 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase 3 223 2.8E-110 T 14-10-2018 IPR014165 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase KEGG: 00362+4.1.3.17|KEGG: 00660+4.1.3.17|MetaCyc: PWY-7701 TSH58p_32550 206a57bc594a42b9e802192b9415bd9e 223 SUPERFAMILY SSF89562 21 182 2.88E-49 T 14-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily TSH58p_15880 b77c784af3e0b7a0d7a1dc26734c505f 197 Gene3D G3DSA:2.60.40.1880 47 196 8.9E-6 T 14-10-2018 IPR038696 Invasion protein B superfamily TSH58p_09835 ddf118b3f8ba48165f3938b36cac2763 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 287 3.1E-49 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 TSH58p_09835 ddf118b3f8ba48165f3938b36cac2763 327 SUPERFAMILY SSF53850 34 279 2.42E-5 T 14-10-2018 TSH58p_09835 ddf118b3f8ba48165f3938b36cac2763 327 Gene3D G3DSA:3.40.190.10 129 251 1.4E-80 T 14-10-2018 TSH58p_09835 ddf118b3f8ba48165f3938b36cac2763 327 Gene3D G3DSA:3.40.190.150 32 311 1.4E-80 T 14-10-2018 TSH58p_09835 ddf118b3f8ba48165f3938b36cac2763 327 PIRSF PIRSF017082 1 327 7.3E-92 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 TSH58p_11070 5221c8d7ff27cda9feefeb54eb83b245 282 Pfam PF03618 Kinase/pyrophosphorylase 6 261 9.4E-96 T 14-10-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 TSH58p_11070 5221c8d7ff27cda9feefeb54eb83b245 282 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 4 266 56.728 T 14-10-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein TSH58p_29480 5bfb7a66812b28e17655190793a3dbd6 338 SUPERFAMILY SSF52151 21 329 6.54E-53 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TSH58p_29480 5bfb7a66812b28e17655190793a3dbd6 338 Gene3D G3DSA:3.40.1090.10 14 125 1.6E-18 T 14-10-2018 TSH58p_29480 5bfb7a66812b28e17655190793a3dbd6 338 Pfam PF01734 Patatin-like phospholipase 26 184 3.0E-26 T 14-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 TSH58p_25820 a570b1afa3229f9acd611dabc38a4571 151 SUPERFAMILY SSF55729 11 148 9.47E-24 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_25820 a570b1afa3229f9acd611dabc38a4571 151 Gene3D G3DSA:3.40.630.30 7 145 7.9E-25 T 14-10-2018 TSH58p_25820 a570b1afa3229f9acd611dabc38a4571 151 Pfam PF13508 Acetyltransferase (GNAT) domain 53 129 4.9E-14 T 14-10-2018 IPR000182 GNAT domain TSH58p_16615 3754e29ee060fe5bb3f78120bbbe7412 78 Pfam PF06620 Protein of unknown function (DUF1150) 41 78 6.3E-6 T 14-10-2018 IPR009531 Protein of unknown function DUF1150 TSH58p_11380 3beaa04b96523f40cd15f2b566b7a966 106 Gene3D G3DSA:3.30.70.100 2 96 3.5E-34 T 14-10-2018 TSH58p_11380 3beaa04b96523f40cd15f2b566b7a966 106 Pfam PF03992 Antibiotic biosynthesis monooxygenase 7 78 3.7E-10 T 14-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain TSH58p_11380 3beaa04b96523f40cd15f2b566b7a966 106 SUPERFAMILY SSF54909 3 94 5.37E-23 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel TSH58p_19750 a2ccda1fac14a9e92ad039ae3b2b1cde 395 Pfam PF13480 Acetyltransferase (GNAT) domain 184 313 4.3E-12 T 14-10-2018 IPR038740 BioF2-like, acetyltransferase domain KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 TSH58p_19750 a2ccda1fac14a9e92ad039ae3b2b1cde 395 SUPERFAMILY SSF55729 34 179 2.3E-12 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_19750 a2ccda1fac14a9e92ad039ae3b2b1cde 395 SUPERFAMILY SSF55729 183 337 1.43E-28 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_19750 a2ccda1fac14a9e92ad039ae3b2b1cde 395 Gene3D G3DSA:3.40.630.30 43 342 1.2E-35 T 14-10-2018 TSH58p_19750 a2ccda1fac14a9e92ad039ae3b2b1cde 395 Gene3D G3DSA:3.40.630.30 168 335 1.2E-35 T 14-10-2018 TSH58p_24410 6cfd4d0acd563fcf8d9aa3791376bff0 364 SUPERFAMILY SSF52540 62 360 6.83E-30 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_24410 6cfd4d0acd563fcf8d9aa3791376bff0 364 Gene3D G3DSA:3.40.50.300 22 363 1.1E-62 T 14-10-2018 TSH58p_24410 6cfd4d0acd563fcf8d9aa3791376bff0 364 Pfam PF13469 Sulfotransferase family 68 314 3.9E-30 T 14-10-2018 TSH58p_20980 6a2cc0d1753904ea586d1d2438fdb3a3 346 Gene3D G3DSA:1.20.1530.20 4 334 5.3E-19 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily TSH58p_20980 6a2cc0d1753904ea586d1d2438fdb3a3 346 PIRSF PIRSF005508 1 344 1.5E-113 T 14-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 TSH58p_20980 6a2cc0d1753904ea586d1d2438fdb3a3 346 Pfam PF01758 Sodium Bile acid symporter family 47 242 1.1E-35 T 14-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 TSH58p_20980 6a2cc0d1753904ea586d1d2438fdb3a3 346 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 1 329 2.6E-112 T 14-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 TSH58p_27390 6f82b9f87f80756002482688bd95ac66 229 TIGRFAM TIGR02098 MJ0042_CXXC: MJ0042 family finger-like domain 1 36 5.8E-15 T 14-10-2018 IPR011723 Zinc finger/thioredoxin putative TSH58p_27390 6f82b9f87f80756002482688bd95ac66 229 Pfam PF11906 Protein of unknown function (DUF3426) 96 193 6.9E-7 T 14-10-2018 IPR021834 Protein of unknown function DUF3426 TSH58p_27390 6f82b9f87f80756002482688bd95ac66 229 Pfam PF13717 zinc-ribbon domain 1 35 5.4E-15 T 14-10-2018 IPR011723 Zinc finger/thioredoxin putative TSH58p_00465 9abb07e8f16c834739f71017cb365b15 535 SUPERFAMILY SSF52096 275 535 5.66E-87 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_00465 9abb07e8f16c834739f71017cb365b15 535 Pfam PF01039 Carboxyl transferase domain 48 526 1.2E-148 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 TSH58p_00465 9abb07e8f16c834739f71017cb365b15 535 SUPERFAMILY SSF52096 24 269 3.65E-69 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_00465 9abb07e8f16c834739f71017cb365b15 535 Gene3D G3DSA:3.90.226.10 274 535 7.6E-105 T 14-10-2018 TSH58p_00465 9abb07e8f16c834739f71017cb365b15 535 Gene3D G3DSA:3.90.226.10 1 272 1.4E-97 T 14-10-2018 TSH58p_23660 deb01a1ff4b8738b5a6b72b8e93b0f2a 145 Gene3D G3DSA:1.10.10.10 11 127 3.4E-35 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_23660 deb01a1ff4b8738b5a6b72b8e93b0f2a 145 SUPERFAMILY SSF46785 26 126 6.97E-29 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_23660 deb01a1ff4b8738b5a6b72b8e93b0f2a 145 Pfam PF01638 HxlR-like helix-turn-helix 34 118 5.7E-31 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type TSH58p_08590 56337eebb72aa0cbee14078e24b4eb08 69 SUPERFAMILY SSF89807 3 68 1.23E-25 T 14-10-2018 IPR036694 Dodecin-like superfamily TSH58p_08590 56337eebb72aa0cbee14078e24b4eb08 69 Gene3D G3DSA:3.30.1660.10 2 69 2.3E-34 T 14-10-2018 IPR025543 Dodecin-like TSH58p_08590 56337eebb72aa0cbee14078e24b4eb08 69 Pfam PF07311 Dodecin 5 68 4.5E-30 T 14-10-2018 IPR009923 Dodecin TSH58p_05510 1234c7c36572294d419e792316e49b43 74 Pfam PF09834 Predicted membrane protein (DUF2061) 1 52 9.6E-24 T 14-10-2018 IPR018638 Domain of unknown function DUF2061, membrane TSH58p_12130 54888b2d6f6bb30536be8458226d75d6 229 Pfam PF00005 ABC transporter 21 160 5.0E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_12130 54888b2d6f6bb30536be8458226d75d6 229 SMART SM00382 28 207 6.9E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_12130 54888b2d6f6bb30536be8458226d75d6 229 SUPERFAMILY SSF52540 9 191 7.76E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_12130 54888b2d6f6bb30536be8458226d75d6 229 Gene3D G3DSA:3.40.50.300 7 195 2.1E-42 T 14-10-2018 TSH58p_12130 54888b2d6f6bb30536be8458226d75d6 229 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 6 203 1.3E-63 T 14-10-2018 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004 TSH58p_12130 54888b2d6f6bb30536be8458226d75d6 229 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_19075 86ea76c79f3e8982d12b0ffa6676190c 328 Gene3D G3DSA:3.40.190.170 29 328 3.5E-116 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily TSH58p_19075 86ea76c79f3e8982d12b0ffa6676190c 328 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 36 312 9.2E-89 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 TSH58p_19075 86ea76c79f3e8982d12b0ffa6676190c 328 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 41 286 1.0E-71 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 TSH58p_19075 86ea76c79f3e8982d12b0ffa6676190c 328 PIRSF PIRSF006470 1 327 2.7E-95 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 TSH58p_12650 924909d63a769cb89b0fa881d232e527 277 Pfam PF04397 LytTr DNA-binding domain 183 269 2.2E-17 T 14-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 TSH58p_12650 924909d63a769cb89b0fa881d232e527 277 SMART SM00850 178 271 2.1E-19 T 14-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 TSH58p_18360 d104d6ba0c974ef66cf5daff7e3222b4 552 Gene3D G3DSA:3.40.50.2000 410 421 5.1E-7 T 14-10-2018 TSH58p_18360 d104d6ba0c974ef66cf5daff7e3222b4 552 Gene3D G3DSA:3.40.50.2000 373 409 5.1E-7 T 14-10-2018 TSH58p_18360 d104d6ba0c974ef66cf5daff7e3222b4 552 Pfam PF00534 Glycosyl transferases group 1 194 339 1.1E-13 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 TSH58p_18360 d104d6ba0c974ef66cf5daff7e3222b4 552 SUPERFAMILY SSF53756 152 425 2.98E-41 T 14-10-2018 TSH58p_18360 d104d6ba0c974ef66cf5daff7e3222b4 552 Gene3D G3DSA:3.40.50.2000 181 339 8.1E-25 T 14-10-2018 TSH58p_18360 d104d6ba0c974ef66cf5daff7e3222b4 552 Gene3D G3DSA:3.40.50.2000 122 180 8.1E-25 T 14-10-2018 TSH58p_31425 5e5be279e93fcd1b30339fc33edcb1d9 231 Gene3D G3DSA:1.10.3720.10 13 221 1.1E-48 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_31425 5e5be279e93fcd1b30339fc33edcb1d9 231 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 217 1.7E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_31425 5e5be279e93fcd1b30339fc33edcb1d9 231 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 18 113 4.3E-32 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 TSH58p_31425 5e5be279e93fcd1b30339fc33edcb1d9 231 SUPERFAMILY SSF161098 16 215 1.83E-42 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_11280 a4f97e4bacf319f45142fb70baaf8b08 183 Gene3D G3DSA:3.40.50.620 32 171 5.8E-12 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSH58p_11280 a4f97e4bacf319f45142fb70baaf8b08 183 SUPERFAMILY SSF52402 36 171 7.67E-12 T 14-10-2018 TSH58p_11280 a4f97e4bacf319f45142fb70baaf8b08 183 Pfam PF00582 Universal stress protein family 33 171 5.2E-13 T 14-10-2018 IPR006016 UspA TSH58p_30590 cd75d765705261f8723dc8bac9757643 549 Gene3D G3DSA:3.10.310.70 74 213 1.7E-72 T 14-10-2018 TSH58p_30590 cd75d765705261f8723dc8bac9757643 549 Pfam PF07969 Amidohydrolase family 44 545 1.8E-61 T 14-10-2018 IPR013108 Amidohydrolase 3 TSH58p_30590 cd75d765705261f8723dc8bac9757643 549 SUPERFAMILY SSF51556 55 504 2.95E-20 T 14-10-2018 IPR032466 Metal-dependent hydrolase TSH58p_30590 cd75d765705261f8723dc8bac9757643 549 Gene3D G3DSA:2.30.40.10 4 521 1.7E-72 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_30590 cd75d765705261f8723dc8bac9757643 549 Gene3D G3DSA:3.20.20.140 56 504 1.7E-72 T 14-10-2018 TSH58p_30590 cd75d765705261f8723dc8bac9757643 549 SUPERFAMILY SSF51338 1 546 2.24E-15 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_21775 7efd8059a6701b624db03b15f13f013d 169 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 23 153 8.9E-25 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ TSH58p_32230 f16c14f4c2e8f281da948e855be2c159 259 Gene3D G3DSA:3.40.50.150 12 175 3.0E-14 T 14-10-2018 TSH58p_32230 f16c14f4c2e8f281da948e855be2c159 259 SUPERFAMILY SSF53335 28 161 1.33E-6 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_32230 f16c14f4c2e8f281da948e855be2c159 259 Pfam PF13578 Methyltransferase domain 31 150 8.5E-11 T 14-10-2018 TSH58p_02300 06ffac03ea69f4672103de9078b2e4a4 217 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 13 205 1.3E-63 T 14-10-2018 IPR022301 Integral membrane protein YjbE TSH58p_02300 06ffac03ea69f4672103de9078b2e4a4 217 Pfam PF03741 Integral membrane protein TerC family 15 205 8.7E-43 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 TSH58p_08705 7bba089fc027412996af3f313d6d1a26 262 Pfam PF05742 Transport and Golgi organisation 2 1 157 8.3E-25 T 14-10-2018 IPR008551 Transport and Golgi organisation protein 2 TSH58p_08705 7bba089fc027412996af3f313d6d1a26 262 Gene3D G3DSA:3.60.60.10 2 167 5.7E-7 T 14-10-2018 TSH58p_10090 57a47999adc585e5ec6a0094ebde96fd 262 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 255 7.7E-25 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_10090 57a47999adc585e5ec6a0094ebde96fd 262 SUPERFAMILY SSF161098 64 248 3.53E-28 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_10090 57a47999adc585e5ec6a0094ebde96fd 262 Gene3D G3DSA:1.10.3720.10 61 255 5.7E-21 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_28265 c2cff9ee888ee5678e89ebae69fb52b4 364 Pfam PF03739 Predicted permease YjgP/YjgQ family 9 357 1.4E-61 T 14-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 TSH58p_28265 c2cff9ee888ee5678e89ebae69fb52b4 364 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 6 360 2.0E-83 T 14-10-2018 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 TSH58p_08175 c263b4671e9ad855f92d259ab63c083e 453 SUPERFAMILY SSF63411 259 444 3.0E-47 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TSH58p_08175 c263b4671e9ad855f92d259ab63c083e 453 Gene3D G3DSA:3.30.830.10 38 243 9.6E-39 T 14-10-2018 TSH58p_08175 c263b4671e9ad855f92d259ab63c083e 453 Pfam PF05193 Peptidase M16 inactive domain 197 372 7.7E-29 T 14-10-2018 IPR007863 Peptidase M16, C-terminal TSH58p_08175 c263b4671e9ad855f92d259ab63c083e 453 SUPERFAMILY SSF63411 25 253 4.37E-44 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TSH58p_08175 c263b4671e9ad855f92d259ab63c083e 453 Gene3D G3DSA:3.30.830.10 249 443 1.8E-51 T 14-10-2018 TSH58p_30220 689ba50d25273c1e947068564fa81938 428 SUPERFAMILY SSF103473 14 423 4.45E-57 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_30220 689ba50d25273c1e947068564fa81938 428 Gene3D G3DSA:1.20.1250.20 11 210 4.6E-24 T 14-10-2018 TSH58p_30220 689ba50d25273c1e947068564fa81938 428 Gene3D G3DSA:1.20.1250.20 233 423 1.4E-20 T 14-10-2018 TSH58p_30220 689ba50d25273c1e947068564fa81938 428 Pfam PF07690 Major Facilitator Superfamily 26 350 4.7E-33 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_22130 8fd95cbf7a4d71517426aba9794e2efa 282 Gene3D G3DSA:1.20.1260.10 138 282 4.3E-11 T 14-10-2018 IPR012347 Ferritin-like TSH58p_00775 49ee5340f3df80d604adac643997377f 216 Pfam PF05128 Domain of unknown function (DUF697) 58 202 1.0E-10 T 14-10-2018 IPR021147 Protein of unknown function DUF697 TSH58p_28575 c1519314720fa877afa8c1bc89bba8e0 248 Gene3D G3DSA:3.40.50.12500 1 245 1.7E-87 T 14-10-2018 TSH58p_28575 c1519314720fa877afa8c1bc89bba8e0 248 Pfam PF01177 Asp/Glu/Hydantoin racemase 3 209 5.4E-13 T 14-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TSH58p_00640 715819d8ff1abdf87d9129f0991af9ec 205 Gene3D G3DSA:1.25.10.10 13 188 2.7E-21 T 14-10-2018 IPR011989 Armadillo-like helical TSH58p_00640 715819d8ff1abdf87d9129f0991af9ec 205 Pfam PF13646 HEAT repeats 118 191 2.1E-8 T 14-10-2018 TSH58p_00640 715819d8ff1abdf87d9129f0991af9ec 205 Pfam PF13646 HEAT repeats 25 103 1.2E-10 T 14-10-2018 TSH58p_00640 715819d8ff1abdf87d9129f0991af9ec 205 SUPERFAMILY SSF48371 25 181 2.95E-20 T 14-10-2018 IPR016024 Armadillo-type fold TSH58p_31120 bfb3ab24735fe50f55c567822712e88a 500 Gene3D G3DSA:3.90.76.10 36 180 9.7E-125 T 14-10-2018 TSH58p_31120 bfb3ab24735fe50f55c567822712e88a 500 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 69 417 2.4E-91 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain TSH58p_31120 bfb3ab24735fe50f55c567822712e88a 500 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 75 97 - T 14-10-2018 IPR023765 Solute-binding protein family 5, conserved site TSH58p_31120 bfb3ab24735fe50f55c567822712e88a 500 PIRSF PIRSF002741 17 497 9.7E-102 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TSH58p_31120 bfb3ab24735fe50f55c567822712e88a 500 Gene3D G3DSA:3.10.105.10 256 473 9.7E-125 T 14-10-2018 TSH58p_31120 bfb3ab24735fe50f55c567822712e88a 500 Gene3D G3DSA:3.40.190.10 181 483 9.7E-125 T 14-10-2018 TSH58p_31120 bfb3ab24735fe50f55c567822712e88a 500 SUPERFAMILY SSF53850 23 498 1.3E-134 T 14-10-2018 TSH58p_00420 93c134a29a3d2eacef0c990be749f5dd 295 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 279 1.1E-34 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_27150 f2b4c8254f7501f93cd1f634d7161217 299 Pfam PF00892 EamA-like transporter family 162 297 1.2E-19 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_27150 f2b4c8254f7501f93cd1f634d7161217 299 Pfam PF00892 EamA-like transporter family 20 150 5.1E-22 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_27150 f2b4c8254f7501f93cd1f634d7161217 299 SUPERFAMILY SSF103481 51 153 9.02E-17 T 14-10-2018 TSH58p_27150 f2b4c8254f7501f93cd1f634d7161217 299 SUPERFAMILY SSF103481 198 298 6.28E-12 T 14-10-2018 TSH58p_15435 6fa144759270ffe6c54e260674227ae4 112 Pfam PF10685 Stress-induced bacterial acidophilic repeat motif 62 82 4.5E-10 T 14-10-2018 IPR019626 Stress-induced protein, KGG, repeat TSH58p_15435 6fa144759270ffe6c54e260674227ae4 112 Pfam PF10685 Stress-induced bacterial acidophilic repeat motif 18 38 4.4E-9 T 14-10-2018 IPR019626 Stress-induced protein, KGG, repeat TSH58p_15435 6fa144759270ffe6c54e260674227ae4 112 Pfam PF10685 Stress-induced bacterial acidophilic repeat motif 40 60 8.6E-10 T 14-10-2018 IPR019626 Stress-induced protein, KGG, repeat TSH58p_15435 6fa144759270ffe6c54e260674227ae4 112 Pfam PF10685 Stress-induced bacterial acidophilic repeat motif 84 104 1.7E-10 T 14-10-2018 IPR019626 Stress-induced protein, KGG, repeat TSH58p_26850 3482b4692d7915358781714e9cddbaa4 159 SUPERFAMILY SSF54593 5 157 5.0E-48 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSH58p_26850 3482b4692d7915358781714e9cddbaa4 159 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 120 1.5E-48 T 14-10-2018 IPR028973 PhnB-like TSH58p_26850 3482b4692d7915358781714e9cddbaa4 159 PIRSF PIRSF021700 1 159 2.1E-65 T 14-10-2018 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase TSH58p_26850 3482b4692d7915358781714e9cddbaa4 159 Gene3D G3DSA:3.10.180.70 1 159 2.0E-61 T 14-10-2018 TSH58p_21440 dbf43fac49b6e7f8928123be1f241cb6 332 SUPERFAMILY SSF51430 1 314 8.51E-93 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TSH58p_21440 dbf43fac49b6e7f8928123be1f241cb6 332 Gene3D G3DSA:3.20.20.100 3 329 1.0E-118 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TSH58p_21440 dbf43fac49b6e7f8928123be1f241cb6 332 Pfam PF00248 Aldo/keto reductase family 16 314 2.0E-72 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain TSH58p_27645 358fcc50f160e59a01dabefc121328ca 377 SUPERFAMILY SSF56601 15 359 1.18E-72 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TSH58p_27645 358fcc50f160e59a01dabefc121328ca 377 Gene3D G3DSA:3.40.710.10 94 376 1.8E-77 T 14-10-2018 TSH58p_27645 358fcc50f160e59a01dabefc121328ca 377 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 124 342 2.5E-55 T 14-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 TSH58p_27645 358fcc50f160e59a01dabefc121328ca 377 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 229 242 7.2E-11 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 TSH58p_27645 358fcc50f160e59a01dabefc121328ca 377 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 149 160 7.2E-11 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 TSH58p_27645 358fcc50f160e59a01dabefc121328ca 377 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 202 219 7.2E-11 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 TSH58p_12955 0ecce848988edde9c9a38205d1a5f6d2 44 Pfam PF00468 Ribosomal protein L34 2 44 2.1E-23 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_12955 0ecce848988edde9c9a38205d1a5f6d2 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.026 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_12955 0ecce848988edde9c9a38205d1a5f6d2 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 2 39 3.0E-11 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_12955 0ecce848988edde9c9a38205d1a5f6d2 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 2 44 5.4E-23 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_12955 0ecce848988edde9c9a38205d1a5f6d2 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 14-10-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSH58p_00075 31a478f317097d409470ef5bedc38775 133 Pfam PF07166 Protein of unknown function (DUF1398) 74 122 1.3E-4 T 14-10-2018 IPR009833 Uncharacterised protein DUF1398 TSH58p_00075 31a478f317097d409470ef5bedc38775 133 SUPERFAMILY SSF160419 77 123 1.2E-7 T 14-10-2018 IPR036696 YdfO-like superfamily TSH58p_00075 31a478f317097d409470ef5bedc38775 133 SUPERFAMILY SSF160419 10 56 7.72E-5 T 14-10-2018 IPR036696 YdfO-like superfamily TSH58p_13470 aba105a21714005857aadac80fbfa305 623 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 109 519 4.5E-79 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain TSH58p_13470 aba105a21714005857aadac80fbfa305 623 Gene3D G3DSA:3.10.105.10 325 584 3.3E-262 T 14-10-2018 TSH58p_13470 aba105a21714005857aadac80fbfa305 623 SUPERFAMILY SSF53850 58 605 1.3E-124 T 14-10-2018 TSH58p_13470 aba105a21714005857aadac80fbfa305 623 PIRSF PIRSF002741 15 610 2.5E-103 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TSH58p_13470 aba105a21714005857aadac80fbfa305 623 Gene3D G3DSA:3.40.190.10 36 605 3.3E-262 T 14-10-2018 TSH58p_07005 acc844791aea1c055044e2713624e526 888 PIRSF PIRSF035905 24 883 6.9E-122 T 14-10-2018 IPR014600 Uncharacterised conserved protein UCP035905, membrane protein TSH58p_07005 acc844791aea1c055044e2713624e526 888 Pfam PF10101 Predicted membrane protein (DUF2339) 100 400 1.2E-57 T 14-10-2018 IPR019286 Protein of unknown function DUF2339, transmembrane TSH58p_07005 acc844791aea1c055044e2713624e526 888 Pfam PF10101 Predicted membrane protein (DUF2339) 438 876 1.3E-79 T 14-10-2018 IPR019286 Protein of unknown function DUF2339, transmembrane TSH58p_13495 71b70af56f80879f21ad2f48f8b1c232 260 Pfam PF00459 Inositol monophosphatase family 8 257 2.3E-52 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_13495 71b70af56f80879f21ad2f48f8b1c232 260 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 83 96 - T 14-10-2018 IPR020583 Inositol monophosphatase, metal-binding site TSH58p_13495 71b70af56f80879f21ad2f48f8b1c232 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 63 79 2.0E-14 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_13495 71b70af56f80879f21ad2f48f8b1c232 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 83 99 2.0E-14 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_13495 71b70af56f80879f21ad2f48f8b1c232 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 41 61 2.0E-14 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_13495 71b70af56f80879f21ad2f48f8b1c232 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 207 231 2.0E-14 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSH58p_13495 71b70af56f80879f21ad2f48f8b1c232 260 SUPERFAMILY SSF56655 8 258 3.93E-71 T 14-10-2018 TSH58p_13495 71b70af56f80879f21ad2f48f8b1c232 260 Gene3D G3DSA:3.40.190.80 146 259 4.9E-30 T 14-10-2018 TSH58p_13495 71b70af56f80879f21ad2f48f8b1c232 260 TIGRFAM TIGR02067 his_9_HisN: histidinol-phosphatase 11 258 3.6E-91 T 14-10-2018 IPR011809 Histidinol-phosphate phosphatase, putative, inositol monophosphatase GO:0004401 KEGG: 00340+3.1.3.15 TSH58p_13495 71b70af56f80879f21ad2f48f8b1c232 260 Gene3D G3DSA:3.30.540.10 7 141 5.2E-43 T 14-10-2018 TSH58p_24745 db599ba97add67a0b1b70cb9652ca8c6 72 SMART SM00316 4 72 9.1E-5 T 14-10-2018 IPR022967 RNA-binding domain, S1 TSH58p_24745 db599ba97add67a0b1b70cb9652ca8c6 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 4.3E-28 T 14-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 TSH58p_24745 db599ba97add67a0b1b70cb9652ca8c6 72 SUPERFAMILY SSF50249 1 71 4.86E-28 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_24745 db599ba97add67a0b1b70cb9652ca8c6 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 26.898 T 14-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 TSH58p_24745 db599ba97add67a0b1b70cb9652ca8c6 72 Gene3D G3DSA:2.40.50.140 1 72 3.1E-37 T 14-10-2018 TSH58p_24745 db599ba97add67a0b1b70cb9652ca8c6 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 1.9E-35 T 14-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 TSH58p_29585 d5cfaa5f05b2408b3b8a652cc670820b 122 Gene3D G3DSA:1.10.1660.10 14 102 4.4E-18 T 14-10-2018 TSH58p_29585 d5cfaa5f05b2408b3b8a652cc670820b 122 Pfam PF13591 MerR HTH family regulatory protein 21 95 3.5E-12 T 14-10-2018 TSH58p_32505 5eeb1c4a13e5588c44afc0c50d70ea06 369 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 179 1.5E-31 T 14-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase TSH58p_06005 23360d6003c6f6c7925685c4726c7f4f 138 Gene3D G3DSA:3.40.630.30 11 136 8.7E-23 T 14-10-2018 TSH58p_06005 23360d6003c6f6c7925685c4726c7f4f 138 SUPERFAMILY SSF55729 15 129 3.54E-16 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_06005 23360d6003c6f6c7925685c4726c7f4f 138 Pfam PF13673 Acetyltransferase (GNAT) domain 39 132 9.4E-12 T 14-10-2018 IPR000182 GNAT domain TSH58p_27445 3b1c5588292ae8008110571770b8961d 179 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 30 161 3.4E-21 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ TSH58p_06840 218d23aeadfe9d2c4690143c44984bc3 111 Pfam PF04380 Membrane fusogenic activity 3 78 4.7E-25 T 14-10-2018 IPR007475 Membrane fusogenic activity TSH58p_07390 d6f635f7bc1b6700804c5a7f42b6c621 220 Pfam PF00326 Prolyl oligopeptidase family 147 212 2.5E-5 T 14-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TSH58p_07390 d6f635f7bc1b6700804c5a7f42b6c621 220 Gene3D G3DSA:3.40.50.1820 2 217 3.0E-66 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_07390 d6f635f7bc1b6700804c5a7f42b6c621 220 SUPERFAMILY SSF53474 4 211 1.35E-49 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_07390 d6f635f7bc1b6700804c5a7f42b6c621 220 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 30 138 4.8E-9 T 14-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 TSH58p_08320 9987255557fc834109db78e2025d4d14 216 SUPERFAMILY SSF161098 12 201 5.23E-37 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_08320 9987255557fc834109db78e2025d4d14 216 Gene3D G3DSA:1.10.3720.10 7 214 2.1E-45 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_08320 9987255557fc834109db78e2025d4d14 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 212 5.4E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_08320 9987255557fc834109db78e2025d4d14 216 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 107 7.9E-22 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 TSH58p_08035 40282cf88cb2348dfe3330927c47bd1b 178 TIGRFAM TIGR01841 phasin: phasin family protein 86 169 1.1E-11 T 14-10-2018 IPR010127 Phasin, subfamily 1 TSH58p_08035 40282cf88cb2348dfe3330927c47bd1b 178 Pfam PF09361 Phasin protein 67 165 7.3E-23 T 14-10-2018 IPR018968 Phasin TSH58p_22885 d96bd5cb58f1ae03e8ca0088f77f8d3d 198 Pfam PF00694 Aconitase C-terminal domain 45 116 2.5E-19 T 14-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 TSH58p_22885 d96bd5cb58f1ae03e8ca0088f77f8d3d 198 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 194 35.333 T 14-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 TSH58p_22885 d96bd5cb58f1ae03e8ca0088f77f8d3d 198 SUPERFAMILY SSF52016 1 185 4.91E-46 T 14-10-2018 TSH58p_22885 d96bd5cb58f1ae03e8ca0088f77f8d3d 198 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 180 3.5E-52 T 14-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 TSH58p_22885 d96bd5cb58f1ae03e8ca0088f77f8d3d 198 Gene3D G3DSA:3.20.19.10 1 168 1.8E-59 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 TSH58p_22900 3a9c72f7c094c7aea086c97750e36532 204 Gene3D G3DSA:3.40.50.850 1 204 1.5E-42 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TSH58p_22900 3a9c72f7c094c7aea086c97750e36532 204 Pfam PF00857 Isochorismatase family 11 191 2.0E-35 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 TSH58p_22900 3a9c72f7c094c7aea086c97750e36532 204 SUPERFAMILY SSF52499 6 201 7.98E-41 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TSH58p_15505 fc7ab42e6ab54750e589ff44d63f8489 256 Pfam PF01311 Bacterial export proteins, family 1 13 246 9.5E-56 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 TSH58p_15505 fc7ab42e6ab54750e589ff44d63f8489 256 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 81 100 2.1E-17 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 TSH58p_15505 fc7ab42e6ab54750e589ff44d63f8489 256 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 21 42 2.1E-17 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 TSH58p_15505 fc7ab42e6ab54750e589ff44d63f8489 256 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 203 222 2.1E-17 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 TSH58p_15505 fc7ab42e6ab54750e589ff44d63f8489 256 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 181 203 2.1E-17 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 TSH58p_15505 fc7ab42e6ab54750e589ff44d63f8489 256 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 13 249 7.5E-53 T 14-10-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 TSH58p_14545 8f8cbbc227a40e640af7e624b768adaf 686 SUPERFAMILY SSF48208 211 679 2.59E-77 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TSH58p_14545 8f8cbbc227a40e640af7e624b768adaf 686 Gene3D G3DSA:1.50.10.10 334 676 2.7E-38 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 TSH58p_14545 8f8cbbc227a40e640af7e624b768adaf 686 Pfam PF12439 Glycogen debranching enzyme N terminal 24 251 2.1E-55 T 14-10-2018 IPR024742 Glycogen debranching enzyme, bacterial and archaeal type, N-terminal TSH58p_14545 8f8cbbc227a40e640af7e624b768adaf 686 Pfam PF06202 Amylo-alpha-1,6-glucosidase 321 677 3.0E-123 T 14-10-2018 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-6798695|Reactome: R-HSA-70221 TSH58p_14545 8f8cbbc227a40e640af7e624b768adaf 686 TIGRFAM TIGR01561 gde_arch: putative glycogen debranching enzyme, archaeal type 24 621 1.3E-117 T 14-10-2018 IPR006451 Glycogen debranching enzyme, archaeal type TSH58p_19035 ed3dd259dc713f927dd1b81d971055a2 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 53 76 3.3E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_19035 ed3dd259dc713f927dd1b81d971055a2 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 45 3.3E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_19035 ed3dd259dc713f927dd1b81d971055a2 225 Gene3D G3DSA:1.10.357.10 19 222 6.5E-55 T 14-10-2018 TSH58p_19035 ed3dd259dc713f927dd1b81d971055a2 225 SUPERFAMILY SSF46689 21 97 3.74E-20 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_19035 ed3dd259dc713f927dd1b81d971055a2 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 78 2.9E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_19035 ed3dd259dc713f927dd1b81d971055a2 225 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 165 217 2.3E-11 T 14-10-2018 IPR039536 Transcriptional regulator TetR, C-terminal, Proteobacteria type TSH58p_19035 ed3dd259dc713f927dd1b81d971055a2 225 SUPERFAMILY SSF48498 101 219 1.54E-8 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TSH58p_19495 0bb458f88ec50583764b5aa91f09faaa 290 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 275 7.5E-36 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_24225 b35fd52ea410835220134332ce20fcd1 303 Gene3D G3DSA:1.10.101.10 25 96 4.4E-8 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 TSH58p_24225 b35fd52ea410835220134332ce20fcd1 303 Pfam PF01471 Putative peptidoglycan binding domain 37 92 3.2E-11 T 14-10-2018 IPR002477 Peptidoglycan binding-like TSH58p_24225 b35fd52ea410835220134332ce20fcd1 303 SUPERFAMILY SSF47090 32 92 1.1E-10 T 14-10-2018 IPR036365 PGBD-like superfamily TSH58p_15980 ff020c559a13360322e4552186b95c9f 252 SUPERFAMILY SSF53335 13 153 7.15E-19 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_15980 ff020c559a13360322e4552186b95c9f 252 Gene3D G3DSA:3.40.50.150 2 213 5.4E-35 T 14-10-2018 TSH58p_30365 7f351017a9069e28b73cd4912faad400 300 Pfam PF02915 Rubrerythrin 109 196 3.4E-5 T 14-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TSH58p_30365 7f351017a9069e28b73cd4912faad400 300 Pfam PF02915 Rubrerythrin 17 66 1.1E-5 T 14-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TSH58p_30365 7f351017a9069e28b73cd4912faad400 300 Gene3D G3DSA:1.20.1260.10 11 161 4.0E-46 T 14-10-2018 IPR012347 Ferritin-like TSH58p_30365 7f351017a9069e28b73cd4912faad400 300 SUPERFAMILY SSF47240 14 163 1.13E-28 T 14-10-2018 IPR009078 Ferritin-like superfamily TSH58p_14475 0297e4f66cc0bf89c6195dc87eb7fc92 75 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 6 68 2.7E-9 T 14-10-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system TSH58p_14475 0297e4f66cc0bf89c6195dc87eb7fc92 75 Gene3D G3DSA:3.30.160.250 5 75 3.1E-16 T 14-10-2018 TSH58p_14475 0297e4f66cc0bf89c6195dc87eb7fc92 75 SUPERFAMILY SSF143100 14 67 5.23E-15 T 14-10-2018 IPR035069 TTHA1013/TTHA0281-like TSH58p_30930 ed0cf2eb7d70043c7a9f0c8c67c1bfeb 285 SUPERFAMILY SSF51197 9 283 9.16E-95 T 14-10-2018 TSH58p_30930 ed0cf2eb7d70043c7a9f0c8c67c1bfeb 285 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 11 276 4.4E-71 T 14-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 TSH58p_30930 ed0cf2eb7d70043c7a9f0c8c67c1bfeb 285 Gene3D G3DSA:3.60.130.10 7 283 8.6E-97 T 14-10-2018 TSH58p_04615 8c028c0c693326f0fb4dedc29cf38046 384 Pfam PF04230 Polysaccharide pyruvyl transferase 14 297 5.7E-38 T 14-10-2018 IPR007345 Polysaccharide pyruvyl transferase TSH58p_24985 d5e8dec19080d5b41c6d314aa2e80667 150 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 133 2.6E-36 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type TSH58p_24985 d5e8dec19080d5b41c6d314aa2e80667 150 Gene3D G3DSA:1.10.10.10 1 143 2.5E-43 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_24985 d5e8dec19080d5b41c6d314aa2e80667 150 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 48 66 - T 14-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site TSH58p_24985 d5e8dec19080d5b41c6d314aa2e80667 150 Pfam PF02082 Transcriptional regulator 1 82 4.0E-27 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type TSH58p_24985 d5e8dec19080d5b41c6d314aa2e80667 150 SUPERFAMILY SSF46785 1 137 4.39E-34 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_24055 5d756b5ea7d8fda239fb38f2b925d13b 259 Gene3D G3DSA:3.30.950.10 122 257 1.0E-52 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 TSH58p_24055 5d756b5ea7d8fda239fb38f2b925d13b 259 Gene3D G3DSA:3.40.1010.10 3 121 8.3E-24 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 TSH58p_24055 5d756b5ea7d8fda239fb38f2b925d13b 259 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 10 256 9.1E-86 T 14-10-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 TSH58p_24055 5d756b5ea7d8fda239fb38f2b925d13b 259 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 12 219 2.8E-32 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 TSH58p_24055 5d756b5ea7d8fda239fb38f2b925d13b 259 SUPERFAMILY SSF53790 7 257 3.79E-51 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 TSH58p_02195 b822d940803de01e3dd1fe7434715fb7 231 SUPERFAMILY SSF109604 16 229 1.26E-56 T 14-10-2018 TSH58p_02195 b822d940803de01e3dd1fe7434715fb7 231 Gene3D G3DSA:1.10.3210.50 8 231 7.4E-65 T 14-10-2018 TSH58p_02195 b822d940803de01e3dd1fe7434715fb7 231 SMART SM00471 28 156 4.8E-11 T 14-10-2018 IPR003607 HD/PDEase domain TSH58p_02195 b822d940803de01e3dd1fe7434715fb7 231 Pfam PF01966 HD domain 34 145 3.5E-11 T 14-10-2018 IPR006674 HD domain TSH58p_23015 60d912e853edfb4688a3b5b78dba7fd6 345 Gene3D G3DSA:3.60.110.10 1 344 7.4E-145 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TSH58p_23015 60d912e853edfb4688a3b5b78dba7fd6 345 SUPERFAMILY SSF56317 10 275 5.36E-53 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TSH58p_23015 60d912e853edfb4688a3b5b78dba7fd6 345 Pfam PF00795 Carbon-nitrogen hydrolase 15 267 3.8E-47 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 TSH58p_31715 371c94271b98fc1460f9df7b03f06d89 260 Gene3D G3DSA:1.10.3720.10 1 249 6.5E-33 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_31715 371c94271b98fc1460f9df7b03f06d89 260 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 61 239 2.8E-10 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_31715 371c94271b98fc1460f9df7b03f06d89 260 SUPERFAMILY SSF161098 2 255 1.57E-37 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_15290 df2ca2cf1e52f933152357acef42866b 376 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 6 291 6.1E-93 T 14-10-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 TSH58p_15290 df2ca2cf1e52f933152357acef42866b 376 Gene3D G3DSA:3.30.590.20 1 365 2.7E-107 T 14-10-2018 TSH58p_15290 df2ca2cf1e52f933152357acef42866b 376 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 376 89.638 T 14-10-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 TSH58p_15290 df2ca2cf1e52f933152357acef42866b 376 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 7 287 4.1E-53 T 14-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 TSH58p_15290 df2ca2cf1e52f933152357acef42866b 376 SUPERFAMILY SSF55931 3 370 2.72E-107 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TSH58p_01685 e88e7a5ab8a15309fa965953729fb80d 399 Pfam PF00872 Transposase, Mutator family 3 371 9.6E-131 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 TSH58p_18225 e88e7a5ab8a15309fa965953729fb80d 399 Pfam PF00872 Transposase, Mutator family 3 371 9.6E-131 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 TSH58p_25285 e88e7a5ab8a15309fa965953729fb80d 399 Pfam PF00872 Transposase, Mutator family 3 371 9.6E-131 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 TSH58p_23825 96b9a998d016a7bdf9130261a17199a1 106 SUPERFAMILY SSF69118 6 104 4.45E-19 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TSH58p_23825 96b9a998d016a7bdf9130261a17199a1 106 Gene3D G3DSA:1.20.1290.10 2 104 4.0E-18 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TSH58p_23825 96b9a998d016a7bdf9130261a17199a1 106 Pfam PF02627 Carboxymuconolactone decarboxylase family 19 100 5.1E-12 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TSH58p_23285 0117a52a59f585a4ee474e68d45f1387 185 Gene3D G3DSA:2.30.110.20 3 184 2.2E-16 T 14-10-2018 IPR036624 Hcp1-like superfamily TSH58p_23285 0117a52a59f585a4ee474e68d45f1387 185 Pfam PF05638 Type VI secretion system effector, Hcp 7 163 1.7E-14 T 14-10-2018 IPR008514 Type VI secretion system effector, Hcp TSH58p_23285 0117a52a59f585a4ee474e68d45f1387 185 SUPERFAMILY SSF141452 4 166 1.96E-15 T 14-10-2018 IPR036624 Hcp1-like superfamily TSH58p_12995 1029a61d82f459e95f356148fd086129 317 Pfam PF13692 Glycosyl transferases group 1 123 256 1.0E-15 T 14-10-2018 TSH58p_12995 1029a61d82f459e95f356148fd086129 317 Gene3D G3DSA:3.40.50.2000 107 280 1.6E-24 T 14-10-2018 TSH58p_12995 1029a61d82f459e95f356148fd086129 317 SUPERFAMILY SSF53756 34 284 7.33E-30 T 14-10-2018 TSH58p_12995 1029a61d82f459e95f356148fd086129 317 Gene3D G3DSA:3.40.50.2000 48 106 1.6E-24 T 14-10-2018 TSH58p_21620 79f7f99aaa462fa91468fc847626f27c 211 Pfam PF01810 LysE type translocator 17 205 2.7E-29 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 TSH58p_30775 2db7c2677fcd3a9367ca7ca812e9aed2 264 SUPERFAMILY SSF161098 58 243 1.64E-22 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_30775 2db7c2677fcd3a9367ca7ca812e9aed2 264 Gene3D G3DSA:1.10.3720.10 52 260 5.9E-18 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_30775 2db7c2677fcd3a9367ca7ca812e9aed2 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 260 3.0E-24 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_09715 c76c633307ff8a3672d5bcd69661e82f 144 SUPERFAMILY SSF54593 12 136 5.37E-25 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSH58p_09715 c76c633307ff8a3672d5bcd69661e82f 144 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 132 2.8E-10 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TSH58p_09715 c76c633307ff8a3672d5bcd69661e82f 144 Gene3D G3DSA:3.10.180.10 4 142 4.9E-38 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSH58p_01525 086a5e70f256da78fac08a3d79594c06 356 SUPERFAMILY SSF52768 27 327 1.98E-27 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily TSH58p_01525 086a5e70f256da78fac08a3d79594c06 356 Pfam PF00491 Arginase family 46 282 4.8E-20 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 TSH58p_01525 086a5e70f256da78fac08a3d79594c06 356 Gene3D G3DSA:3.40.800.10 14 335 1.1E-27 T 14-10-2018 TSH58p_01525 086a5e70f256da78fac08a3d79594c06 356 PIRSF PIRSF036979 27 318 9.8E-14 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 TSH58p_19605 ed069766ec43479e98208cad5f0d8828 434 Pfam PF01266 FAD dependent oxidoreductase 38 390 1.0E-57 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TSH58p_19605 ed069766ec43479e98208cad5f0d8828 434 Gene3D G3DSA:3.30.9.10 132 353 4.6E-77 T 14-10-2018 TSH58p_19605 ed069766ec43479e98208cad5f0d8828 434 Gene3D G3DSA:3.50.50.60 38 390 4.6E-77 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_19605 ed069766ec43479e98208cad5f0d8828 434 SUPERFAMILY SSF51905 37 413 2.72E-46 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_19515 ace9139b5e573855a943f257c8c6f9a4 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 8.8E-22 T 14-10-2018 TSH58p_19515 ace9139b5e573855a943f257c8c6f9a4 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 8.8E-22 T 14-10-2018 TSH58p_19515 ace9139b5e573855a943f257c8c6f9a4 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 328 344 8.8E-22 T 14-10-2018 TSH58p_19515 ace9139b5e573855a943f257c8c6f9a4 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 8.8E-22 T 14-10-2018 TSH58p_19515 ace9139b5e573855a943f257c8c6f9a4 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 8.8E-22 T 14-10-2018 TSH58p_19515 ace9139b5e573855a943f257c8c6f9a4 403 Pfam PF01494 FAD binding domain 3 339 6.3E-27 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 TSH58p_19515 ace9139b5e573855a943f257c8c6f9a4 403 SUPERFAMILY SSF51905 1 371 1.69E-66 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_19515 ace9139b5e573855a943f257c8c6f9a4 403 Gene3D G3DSA:3.30.9.30 35 352 6.2E-120 T 14-10-2018 TSH58p_19515 ace9139b5e573855a943f257c8c6f9a4 403 Gene3D G3DSA:3.50.50.60 3 344 6.2E-120 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_19515 ace9139b5e573855a943f257c8c6f9a4 403 SUPERFAMILY SSF54373 172 272 3.92E-17 T 14-10-2018 TSH58p_10490 70c93f47b24eb78f86c5502f0a73fdff 64 Pfam PF06945 Protein of unknown function (DUF1289) 12 59 4.3E-21 T 14-10-2018 IPR010710 Protein of unknown function DUF1289 TSH58p_29110 8da9664cfbb8779a27d5beff9d05d6e5 319 Pfam PF02470 MlaD protein 39 115 4.9E-17 T 14-10-2018 IPR003399 Mce/MlaD TSH58p_22255 5a9489e7079cd265d5c6e51f22f2ca12 183 Pfam PF07813 LTXXQ motif family protein 81 175 1.5E-21 T 14-10-2018 IPR012899 LTXXQ motif family protein GO:0042597 TSH58p_13755 5f6488a5fed5ee8514539d8b2cd10ca7 105 SUPERFAMILY SSF141091 1 102 6.41E-40 T 14-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_13755 5f6488a5fed5ee8514539d8b2cd10ca7 105 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 28.054 T 14-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_13755 5f6488a5fed5ee8514539d8b2cd10ca7 105 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 1.3E-35 T 14-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_13755 5f6488a5fed5ee8514539d8b2cd10ca7 105 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 3.9E-43 T 14-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSH58p_19775 762483716eee584b53e61b7ccffbcd4d 293 Gene3D G3DSA:3.40.190.290 90 293 5.4E-43 T 14-10-2018 TSH58p_19775 762483716eee584b53e61b7ccffbcd4d 293 SUPERFAMILY SSF46785 1 85 2.46E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_19775 762483716eee584b53e61b7ccffbcd4d 293 SUPERFAMILY SSF53850 90 292 1.01E-40 T 14-10-2018 TSH58p_19775 762483716eee584b53e61b7ccffbcd4d 293 Gene3D G3DSA:1.10.10.10 1 84 4.7E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_19775 762483716eee584b53e61b7ccffbcd4d 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.4E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_19775 762483716eee584b53e61b7ccffbcd4d 293 Pfam PF03466 LysR substrate binding domain 88 291 1.2E-44 T 14-10-2018 IPR005119 LysR, substrate-binding TSH58p_19775 762483716eee584b53e61b7ccffbcd4d 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_19775 762483716eee584b53e61b7ccffbcd4d 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_19775 762483716eee584b53e61b7ccffbcd4d 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSH58p_03655 ed74e45d44f6ada6ce0b5c488fe0b175 136 SMART SM00448 10 127 4.9E-10 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_03655 ed74e45d44f6ada6ce0b5c488fe0b175 136 Gene3D G3DSA:3.40.50.2300 4 132 9.9E-15 T 14-10-2018 TSH58p_03655 ed74e45d44f6ada6ce0b5c488fe0b175 136 Pfam PF00072 Response regulator receiver domain 12 127 1.2E-9 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_03655 ed74e45d44f6ada6ce0b5c488fe0b175 136 SUPERFAMILY SSF52172 8 130 1.85E-16 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_24025 8e73d0fea5d15fdedc67d4561c29c654 254 Gene3D G3DSA:3.40.50.300 4 251 1.1E-54 T 14-10-2018 TSH58p_24025 8e73d0fea5d15fdedc67d4561c29c654 254 SUPERFAMILY SSF52540 5 247 3.52E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_24025 8e73d0fea5d15fdedc67d4561c29c654 254 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 247 1.4E-6 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSH58p_24025 8e73d0fea5d15fdedc67d4561c29c654 254 SMART SM00382 31 225 3.3E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_24025 8e73d0fea5d15fdedc67d4561c29c654 254 Pfam PF00005 ABC transporter 23 177 4.4E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_06155 54b576aeabba1e6324bc9dc4e44a6d60 232 SUPERFAMILY SSF160909 1 227 3.14E-78 T 14-10-2018 TSH58p_06155 54b576aeabba1e6324bc9dc4e44a6d60 232 Pfam PF07542 ATP12 chaperone protein 2 120 2.5E-37 T 14-10-2018 IPR011419 ATP12, ATP synthase F1-assembly protein GO:0043461 TSH58p_06155 54b576aeabba1e6324bc9dc4e44a6d60 232 Gene3D G3DSA:3.30.2180.30 1 61 1.3E-21 T 14-10-2018 TSH58p_06155 54b576aeabba1e6324bc9dc4e44a6d60 232 Gene3D G3DSA:1.10.3580.10 62 232 2.8E-62 T 14-10-2018 IPR023335 ATP12 orthogonal Bundle domain superfamily TSH58p_21465 38174cfefb95070a37e88b19a9093488 507 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 109 505 1.2E-163 T 14-10-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 TSH58p_21465 38174cfefb95070a37e88b19a9093488 507 Pfam PF08666 SAF domain 12 80 3.3E-13 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 TSH58p_21465 38174cfefb95070a37e88b19a9093488 507 Gene3D G3DSA:3.90.1210.30 5 82 1.4E-23 T 14-10-2018 TSH58p_21465 38174cfefb95070a37e88b19a9093488 507 SMART SM00858 12 81 3.0E-13 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 TSH58p_18585 38174cfefb95070a37e88b19a9093488 507 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 109 505 1.2E-163 T 14-10-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 TSH58p_18585 38174cfefb95070a37e88b19a9093488 507 Pfam PF08666 SAF domain 12 80 3.3E-13 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 TSH58p_18585 38174cfefb95070a37e88b19a9093488 507 Gene3D G3DSA:3.90.1210.30 5 82 1.4E-23 T 14-10-2018 TSH58p_18585 38174cfefb95070a37e88b19a9093488 507 SMART SM00858 12 81 3.0E-13 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 TSH58p_14435 472741ad9c6ff5555ab52ac007003551 129 SUPERFAMILY SSF69118 3 126 2.22E-35 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TSH58p_14435 472741ad9c6ff5555ab52ac007003551 129 Gene3D G3DSA:1.20.1290.10 3 129 2.3E-51 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TSH58p_14435 472741ad9c6ff5555ab52ac007003551 129 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 59 106 7.7E-18 T 14-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TSH58p_14435 472741ad9c6ff5555ab52ac007003551 129 Pfam PF02627 Carboxymuconolactone decarboxylase family 43 118 1.5E-17 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TSH58p_16870 70df3b54a56bbf9708fc4f5e92cd126d 319 Pfam PF01728 FtsJ-like methyltransferase 164 251 2.6E-9 T 14-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 TSH58p_16870 70df3b54a56bbf9708fc4f5e92cd126d 319 Gene3D G3DSA:3.40.50.150 157 316 2.7E-45 T 14-10-2018 TSH58p_16870 70df3b54a56bbf9708fc4f5e92cd126d 319 SUPERFAMILY SSF53335 164 284 2.05E-16 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_20985 31910d1de214906d2889456e6be08a32 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 268 2.9E-19 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_20985 31910d1de214906d2889456e6be08a32 269 Gene3D G3DSA:1.10.3720.10 60 265 1.6E-16 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_20985 31910d1de214906d2889456e6be08a32 269 SUPERFAMILY SSF161098 64 251 7.19E-20 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_28930 02ecacfeb3ada6a3521c683982a10f05 183 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 19 154 3.1E-31 T 14-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 TSH58p_28930 02ecacfeb3ada6a3521c683982a10f05 183 Gene3D G3DSA:3.30.420.140 15 166 8.4E-42 T 14-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 TSH58p_28930 02ecacfeb3ada6a3521c683982a10f05 183 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 16 157 24.182 T 14-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 TSH58p_28930 02ecacfeb3ada6a3521c683982a10f05 183 SUPERFAMILY SSF53098 16 155 5.92E-37 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily TSH58p_28930 02ecacfeb3ada6a3521c683982a10f05 183 Pfam PF03652 Holliday junction resolvase 17 154 5.4E-40 T 14-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 TSH58p_28930 02ecacfeb3ada6a3521c683982a10f05 183 SMART SM00732 16 121 1.7E-29 T 14-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 TSH58p_05045 525f880c036db0a9fc239741eb04cca9 249 Pfam PF05239 PRC-barrel domain 58 108 1.7E-5 T 14-10-2018 IPR027275 PRC-barrel domain TSH58p_05045 525f880c036db0a9fc239741eb04cca9 249 Gene3D G3DSA:2.30.30.240 48 124 1.8E-10 T 14-10-2018 TSH58p_05045 525f880c036db0a9fc239741eb04cca9 249 Gene3D G3DSA:2.30.30.240 133 224 5.9E-6 T 14-10-2018 TSH58p_05045 525f880c036db0a9fc239741eb04cca9 249 SUPERFAMILY SSF50346 53 112 1.0E-7 T 14-10-2018 IPR011033 PRC-barrel-like superfamily TSH58p_07960 92a0ae1b9b51782793649b066b4c1048 353 SUPERFAMILY SSF81342 133 343 3.22E-42 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 TSH58p_07960 92a0ae1b9b51782793649b066b4c1048 353 TIGRFAM TIGR01583 formate-DH-gamm: formate dehydrogenase, gamma subunit 137 337 2.1E-47 T 14-10-2018 IPR006471 Formate dehydrogenase, gamma subunit GO:0008863|GO:0009326|GO:0016021|GO:0045333 TSH58p_07960 92a0ae1b9b51782793649b066b4c1048 353 Gene3D G3DSA:1.20.950.20 132 346 2.1E-62 T 14-10-2018 TSH58p_07960 92a0ae1b9b51782793649b066b4c1048 353 Pfam PF01292 Prokaryotic cytochrome b561 139 318 4.6E-18 T 14-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 TSH58p_14020 03cfc4e73b017240562385097d46051c 588 SUPERFAMILY SSF161098 63 258 9.94E-22 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_14020 03cfc4e73b017240562385097d46051c 588 SUPERFAMILY SSF161098 385 573 1.05E-18 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_14020 03cfc4e73b017240562385097d46051c 588 Gene3D G3DSA:1.10.3720.10 61 264 5.8E-25 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_14020 03cfc4e73b017240562385097d46051c 588 Gene3D G3DSA:1.10.3720.10 382 575 5.3E-18 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_14020 03cfc4e73b017240562385097d46051c 588 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 254 2.5E-12 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_14020 03cfc4e73b017240562385097d46051c 588 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 402 586 3.0E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_08555 542c1b4e2e681a3247fd2099eb8d4bb8 209 Gene3D G3DSA:1.10.357.10 79 208 4.7E-29 T 14-10-2018 TSH58p_08555 542c1b4e2e681a3247fd2099eb8d4bb8 209 SUPERFAMILY SSF46689 11 91 6.48E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSH58p_08555 542c1b4e2e681a3247fd2099eb8d4bb8 209 SUPERFAMILY SSF48498 91 202 4.73E-26 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TSH58p_08555 542c1b4e2e681a3247fd2099eb8d4bb8 209 Gene3D G3DSA:1.10.10.60 11 78 1.1E-27 T 14-10-2018 TSH58p_08555 542c1b4e2e681a3247fd2099eb8d4bb8 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 71 4.8E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSH58p_03200 f7612a9ef94d8244edc1c8c34621641e 175 Pfam PF14196 L-2-amino-thiazoline-4-carboxylic acid hydrolase 28 165 3.1E-22 T 14-10-2018 IPR026002 L-2-amino-thiazoline-4-carboxylic acid hydrolase TSH58p_30655 78aaf60ac57b8593830dc124a3f1a019 580 Pfam PF02538 Hydantoinase B/oxoprolinase 18 541 3.8E-168 T 14-10-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 TSH58p_24975 00e514acd293b2917654b3b90036bb22 331 Gene3D G3DSA:3.40.190.10 114 325 7.4E-137 T 14-10-2018 TSH58p_24975 00e514acd293b2917654b3b90036bb22 331 ProSitePatterns PS00757 Prokaryotic sulfate-binding proteins signature 2. 145 153 - T 14-10-2018 IPR034408 Sulphate/thiosulphate-binding site GO:1901681 TSH58p_24975 00e514acd293b2917654b3b90036bb22 331 Pfam PF13531 Bacterial extracellular solute-binding protein 41 280 3.2E-46 T 14-10-2018 TSH58p_24975 00e514acd293b2917654b3b90036bb22 331 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 14 326 5.2E-151 T 14-10-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 TSH58p_24975 00e514acd293b2917654b3b90036bb22 331 SUPERFAMILY SSF53850 21 328 7.17E-93 T 14-10-2018 TSH58p_24975 00e514acd293b2917654b3b90036bb22 331 Gene3D G3DSA:3.40.190.10 27 295 7.4E-137 T 14-10-2018 TSH58p_16965 126932a2d740cd6247629422df8146bf 447 Pfam PF07690 Major Facilitator Superfamily 22 397 5.3E-24 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_16965 126932a2d740cd6247629422df8146bf 447 SUPERFAMILY SSF103473 14 440 1.44E-41 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_16965 126932a2d740cd6247629422df8146bf 447 Gene3D G3DSA:1.20.1250.20 246 445 4.9E-13 T 14-10-2018 TSH58p_16965 126932a2d740cd6247629422df8146bf 447 Gene3D G3DSA:1.20.1250.20 10 206 6.4E-14 T 14-10-2018 TSH58p_27060 2cb3fefc354156da22e2ae22320fcd88 550 Pfam PF05977 Transmembrane secretion effector 25 541 1.1E-196 T 14-10-2018 IPR010290 Transmembrane secretion effector TSH58p_27060 2cb3fefc354156da22e2ae22320fcd88 550 Gene3D G3DSA:1.20.1250.20 26 414 7.1E-38 T 14-10-2018 TSH58p_27060 2cb3fefc354156da22e2ae22320fcd88 550 SUPERFAMILY SSF103473 32 417 9.29E-47 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_23330 996adec36653df4bd1759c9f61011800 674 SMART SM00331 455 665 2.3E-8 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSH58p_23330 996adec36653df4bd1759c9f61011800 674 SUPERFAMILY SSF158472 281 328 1.7E-5 T 14-10-2018 TSH58p_23330 996adec36653df4bd1759c9f61011800 674 Gene3D G3DSA:1.10.8.500 283 332 8.1E-7 T 14-10-2018 TSH58p_23330 996adec36653df4bd1759c9f61011800 674 Gene3D G3DSA:3.60.40.10 425 672 7.7E-40 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSH58p_23330 996adec36653df4bd1759c9f61011800 674 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 482 658 3.5E-22 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSH58p_05635 910e6c2d655f11c6be3b9cd110065183 352 Pfam PF00591 Glycosyl transferase family, a/b domain 86 334 6.9E-103 T 14-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSH58p_05635 910e6c2d655f11c6be3b9cd110065183 352 SUPERFAMILY SSF47648 14 80 1.7E-20 T 14-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSH58p_05635 910e6c2d655f11c6be3b9cd110065183 352 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 16 344 38.95 T 14-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 TSH58p_05635 910e6c2d655f11c6be3b9cd110065183 352 Gene3D G3DSA:1.20.970.10 6 81 2.6E-25 T 14-10-2018 TSH58p_05635 910e6c2d655f11c6be3b9cd110065183 352 Gene3D G3DSA:3.40.1030.10 82 349 5.2E-105 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSH58p_05635 910e6c2d655f11c6be3b9cd110065183 352 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 19 343 2.4E-120 T 14-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 TSH58p_05635 910e6c2d655f11c6be3b9cd110065183 352 SUPERFAMILY SSF52418 85 347 7.33E-93 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSH58p_05635 910e6c2d655f11c6be3b9cd110065183 352 Pfam PF02885 Glycosyl transferase family, helical bundle domain 16 77 4.5E-20 T 14-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSH58p_20055 5f8783df30001c8efa5ad9af761ee4ff 88 Pfam PF11747 Killing trait 11 77 6.0E-29 T 14-10-2018 IPR021070 Killing trait, RebB TSH58p_18365 9107c0e623b41284fbd6b17279196f13 187 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 177 3.9E-66 T 14-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TSH58p_18365 9107c0e623b41284fbd6b17279196f13 187 SUPERFAMILY SSF51182 1 182 4.61E-71 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_18365 9107c0e623b41284fbd6b17279196f13 187 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 3 178 9.4E-63 T 14-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TSH58p_18365 9107c0e623b41284fbd6b17279196f13 187 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 178 8.0E-94 T 14-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TSH58p_18365 9107c0e623b41284fbd6b17279196f13 187 Gene3D G3DSA:2.60.120.10 1 185 1.0E-66 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_01970 46c45503dc20b0e9d7a9032ea554157f 360 SUPERFAMILY SSF88713 58 293 1.17E-18 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TSH58p_01970 46c45503dc20b0e9d7a9032ea554157f 360 Pfam PF01522 Polysaccharide deacetylase 97 292 9.5E-14 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 TSH58p_00100 88f1a1009cd91922958cc4714a5658eb 419 SMART SM00839 180 412 3.7E-77 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSH58p_00100 88f1a1009cd91922958cc4714a5658eb 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 89 103 2.2E-32 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSH58p_00100 88f1a1009cd91922958cc4714a5658eb 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 340 351 2.2E-32 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSH58p_00100 88f1a1009cd91922958cc4714a5658eb 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 169 191 2.2E-32 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSH58p_00100 88f1a1009cd91922958cc4714a5658eb 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 211 231 2.2E-32 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSH58p_00100 88f1a1009cd91922958cc4714a5658eb 419 PIRSF PIRSF000185 2 415 3.6E-157 T 14-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 TSH58p_00100 88f1a1009cd91922958cc4714a5658eb 419 Gene3D G3DSA:3.40.50.10860 34 177 2.0E-57 T 14-10-2018 TSH58p_00100 88f1a1009cd91922958cc4714a5658eb 419 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 34 159 1.2E-49 T 14-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSH58p_00100 88f1a1009cd91922958cc4714a5658eb 419 SUPERFAMILY SSF53223 4 180 4.16E-62 T 14-10-2018 TSH58p_00100 88f1a1009cd91922958cc4714a5658eb 419 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 178 412 3.9E-65 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSH58p_00100 88f1a1009cd91922958cc4714a5658eb 419 SUPERFAMILY SSF51735 178 413 1.08E-63 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_00100 88f1a1009cd91922958cc4714a5658eb 419 Gene3D G3DSA:3.40.50.720 178 415 1.4E-80 T 14-10-2018 TSH58p_23780 6afb96db526d47397aabd21ec2346e20 135 Pfam PF05717 IS66 Orf2 like protein 10 107 1.0E-35 T 14-10-2018 IPR008878 Transposase IS66, Orf2 TSH58p_04405 d7f6bbeb8fb23413967ef8c6998cd3d0 318 Pfam PF13362 Toprim domain 231 316 5.5E-15 T 14-10-2018 IPR006171 TOPRIM domain TSH58p_23630 d0c28fe13f02e1265a7220e483116edd 325 Pfam PF02653 Branched-chain amino acid transport system / permease component 43 302 7.9E-36 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_12285 bfe271fbfe233087813dd38d502f16ea 349 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 42 251 3.0E-21 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_12285 bfe271fbfe233087813dd38d502f16ea 349 Gene3D G3DSA:3.40.190.10 133 230 6.9E-45 T 14-10-2018 TSH58p_12285 bfe271fbfe233087813dd38d502f16ea 349 Gene3D G3DSA:3.40.190.10 31 252 6.9E-45 T 14-10-2018 TSH58p_12285 bfe271fbfe233087813dd38d502f16ea 349 SMART SM00062 41 267 4.0E-19 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_12285 bfe271fbfe233087813dd38d502f16ea 349 SUPERFAMILY SSF53850 32 256 2.34E-36 T 14-10-2018 TSH58p_15540 940e5a05d5c29d415bc7c7b06d459650 281 SUPERFAMILY SSF52540 7 237 3.17E-35 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_15540 940e5a05d5c29d415bc7c7b06d459650 281 Gene3D G3DSA:3.40.50.300 5 199 8.2E-26 T 14-10-2018 TSH58p_15540 940e5a05d5c29d415bc7c7b06d459650 281 Pfam PF07728 AAA domain (dynein-related subfamily) 29 171 8.0E-14 T 14-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 TSH58p_15540 940e5a05d5c29d415bc7c7b06d459650 281 SMART SM00382 25 183 5.3E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_25325 b346fb0f5f9ec5d96f208b5595368bfa 438 SUPERFAMILY SSF52540 31 364 1.42E-6 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_25325 b346fb0f5f9ec5d96f208b5595368bfa 438 Pfam PF10923 P-loop Domain of unknown function (DUF2791) 5 398 4.7E-113 T 14-10-2018 IPR021228 Protein of unknown function DUF2791 TSH58p_18895 ca2a08b445216699d9570a2297341d90 137 SUPERFAMILY SSF46785 17 122 4.58E-30 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_18895 ca2a08b445216699d9570a2297341d90 137 Gene3D G3DSA:1.10.10.10 12 134 1.1E-37 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_18895 ca2a08b445216699d9570a2297341d90 137 Pfam PF01638 HxlR-like helix-turn-helix 36 123 4.7E-26 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type TSH58p_05015 a851a6bc670bce6bc89460d9aace7ef4 275 Pfam PF01774 UreD urease accessory protein 48 248 1.9E-49 T 14-10-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 TSH58p_05015 a851a6bc670bce6bc89460d9aace7ef4 275 Hamap MF_01384 Urease accessory protein UreD [ureD]. 6 259 27.488 T 14-10-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 TSH58p_03325 d9effa8a8850a4cea44b978468f8e11a 562 Pfam PF02652 L-lactate permease 16 553 8.8E-209 T 14-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 TSH58p_03325 d9effa8a8850a4cea44b978468f8e11a 562 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 6 555 1.0E-220 T 14-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 TSH58p_08420 2e12826bdcea612dd76c400e5aa1c1db 94 Pfam PF13436 Glycine-zipper domain 28 68 5.8E-9 T 14-10-2018 IPR025693 Glycine-zipper-containing OmpA-like membrane domain TSH58p_11890 e540455e77f7e5bdf30fa94e6da93bd6 279 SMART SM00318 21 151 1.3E-5 T 14-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 TSH58p_11890 e540455e77f7e5bdf30fa94e6da93bd6 279 Gene3D G3DSA:2.40.50.90 24 159 4.2E-19 T 14-10-2018 IPR035437 SNase-like, OB-fold superfamily TSH58p_11890 e540455e77f7e5bdf30fa94e6da93bd6 279 Pfam PF00565 Staphylococcal nuclease homologue 63 150 7.3E-9 T 14-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 TSH58p_11890 e540455e77f7e5bdf30fa94e6da93bd6 279 SUPERFAMILY SSF50199 26 151 4.71E-21 T 14-10-2018 TSH58p_06145 c01906a476da99143e4a038c74f9e682 203 SUPERFAMILY SSF50346 62 157 3.92E-18 T 14-10-2018 IPR011033 PRC-barrel-like superfamily TSH58p_06145 c01906a476da99143e4a038c74f9e682 203 Pfam PF05239 PRC-barrel domain 69 130 1.1E-12 T 14-10-2018 IPR027275 PRC-barrel domain TSH58p_06145 c01906a476da99143e4a038c74f9e682 203 Gene3D G3DSA:2.30.30.240 61 147 4.1E-26 T 14-10-2018 TSH58p_12560 a5ca124e44bed6bad1589c5513ebd85b 572 Gene3D G3DSA:1.20.1730.10 57 569 1.4E-60 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily TSH58p_12560 a5ca124e44bed6bad1589c5513ebd85b 572 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 69 491 1.1E-61 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 TSH58p_12560 a5ca124e44bed6bad1589c5513ebd85b 572 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 473 493 - T 14-10-2018 IPR018212 Sodium/solute symporter, conserved site TSH58p_12560 a5ca124e44bed6bad1589c5513ebd85b 572 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 184 209 - T 14-10-2018 IPR018212 Sodium/solute symporter, conserved site TSH58p_12560 a5ca124e44bed6bad1589c5513ebd85b 572 Pfam PF00474 Sodium:solute symporter family 69 491 1.3E-114 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 TSH58p_05875 0ae9d64d308b24958a78c09462801b28 162 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 19 140 3.0E-52 T 14-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05875 0ae9d64d308b24958a78c09462801b28 162 Pfam PF12838 4Fe-4S dicluster domain 62 116 1.3E-12 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_05875 0ae9d64d308b24958a78c09462801b28 162 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 102 113 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_05875 0ae9d64d308b24958a78c09462801b28 162 SUPERFAMILY SSF54862 36 146 1.55E-28 T 14-10-2018 TSH58p_05875 0ae9d64d308b24958a78c09462801b28 162 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 10 146 29.192 T 14-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_05875 0ae9d64d308b24958a78c09462801b28 162 Gene3D G3DSA:3.30.70.3270 36 161 1.0E-43 T 14-10-2018 TSH58p_19685 13e9d90cd94e843f9768ee9ade1cc468 178 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 30 157 7.9E-13 T 14-10-2018 IPR009936 Protein of unknown function DUF1468 TSH58p_30280 35249955501215b72f447bad6803f1eb 78 Pfam PF08984 Domain of unknown function (DUF1858) 18 66 1.6E-8 T 14-10-2018 IPR015077 Domain of unknown function DUF1858 TSH58p_30280 35249955501215b72f447bad6803f1eb 78 Gene3D G3DSA:1.10.3910.10 15 77 2.2E-17 T 14-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily TSH58p_30280 35249955501215b72f447bad6803f1eb 78 SUPERFAMILY SSF140683 18 75 1.83E-10 T 14-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily TSH58p_30280 35249955501215b72f447bad6803f1eb 78 TIGRFAM TIGR03980 prismane_assoc: hybrid cluster protein-associated redox disulfide domain 19 69 4.1E-18 T 14-10-2018 IPR023883 Conserved hypothetical protein CHP03980, redox-disulphide TSH58p_26680 ce5b83a9f9761d3425e869c81eb5f281 265 Pfam PF00378 Enoyl-CoA hydratase/isomerase 22 263 4.4E-65 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TSH58p_26680 ce5b83a9f9761d3425e869c81eb5f281 265 Gene3D G3DSA:1.10.12.10 208 265 4.2E-16 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal TSH58p_26680 ce5b83a9f9761d3425e869c81eb5f281 265 Gene3D G3DSA:3.90.226.10 5 207 1.0E-69 T 14-10-2018 TSH58p_26680 ce5b83a9f9761d3425e869c81eb5f281 265 SUPERFAMILY SSF52096 13 264 2.09E-86 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_26680 ce5b83a9f9761d3425e869c81eb5f281 265 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 106 126 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 TSH58p_05405 4361b8b4e6fa32e125e46c2b4887c6c6 143 Gene3D G3DSA:3.40.30.10 1 114 1.0E-16 T 14-10-2018 TSH58p_05405 4361b8b4e6fa32e125e46c2b4887c6c6 143 Pfam PF03960 ArsC family 57 110 9.2E-7 T 14-10-2018 IPR006660 Arsenate reductase-like TSH58p_05405 4361b8b4e6fa32e125e46c2b4887c6c6 143 TIGRFAM TIGR01616 nitro_assoc: nitrogenase-associated protein 3 119 6.2E-42 T 14-10-2018 IPR006503 Nitrogenase-associated protein TSH58p_05405 4361b8b4e6fa32e125e46c2b4887c6c6 143 SUPERFAMILY SSF52833 4 117 3.27E-24 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_31510 23fa54678322bdc0499986c5a9e48bbc 347 SUPERFAMILY SSF53850 41 330 1.18E-21 T 14-10-2018 TSH58p_31510 23fa54678322bdc0499986c5a9e48bbc 347 Gene3D G3DSA:3.40.190.10 34 140 4.0E-8 T 14-10-2018 TSH58p_31510 23fa54678322bdc0499986c5a9e48bbc 347 Pfam PF13379 NMT1-like family 35 281 2.3E-20 T 14-10-2018 TSH58p_31510 23fa54678322bdc0499986c5a9e48bbc 347 Gene3D G3DSA:3.40.190.10 153 340 2.8E-14 T 14-10-2018 TSH58p_19185 201b25dc001182b477540ee4c3954fc9 124 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 21 124 14.601 T 14-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 TSH58p_19185 201b25dc001182b477540ee4c3954fc9 124 Pfam PF02049 Flagellar hook-basal body complex protein FliE 40 124 2.1E-19 T 14-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 TSH58p_08475 42b7dfcd9518ec711f58d432b148d30a 269 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 170 2.0E-24 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TSH58p_08475 42b7dfcd9518ec711f58d432b148d30a 269 Gene3D G3DSA:3.40.50.720 1 266 9.0E-53 T 14-10-2018 TSH58p_08475 42b7dfcd9518ec711f58d432b148d30a 269 SUPERFAMILY SSF51735 1 259 1.64E-53 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_09220 42690f27fdd47d7881c3f6e3a3e61c32 513 Gene3D G3DSA:3.40.50.300 8 205 1.1E-13 T 14-10-2018 TSH58p_08860 2dbb2204f2f44a7044a74102d09592bd 222 Gene3D G3DSA:3.40.50.880 4 222 1.5E-85 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_08860 2dbb2204f2f44a7044a74102d09592bd 222 PIRSF PIRSF006320 5 221 6.0E-93 T 14-10-2018 IPR026041 Glyoxalase ElbB TSH58p_08860 2dbb2204f2f44a7044a74102d09592bd 222 SUPERFAMILY SSF52317 6 218 1.5E-58 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_16235 d00825c69650b79ae84937cdf0f2a94e 114 SUPERFAMILY SSF143100 1 72 6.54E-11 T 14-10-2018 IPR035069 TTHA1013/TTHA0281-like TSH58p_16235 d00825c69650b79ae84937cdf0f2a94e 114 SUPERFAMILY SSF47598 67 106 4.56E-5 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TSH58p_16235 d00825c69650b79ae84937cdf0f2a94e 114 Pfam PF05534 HicB family 62 101 6.2E-10 T 14-10-2018 IPR008651 Uncharacterised protein family HicB TSH58p_30630 09923210b180d877fe5e244b844a3020 548 PIRSF PIRSF002741 17 545 3.1E-140 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TSH58p_30630 09923210b180d877fe5e244b844a3020 548 Gene3D G3DSA:3.10.105.10 293 512 8.9E-55 T 14-10-2018 TSH58p_30630 09923210b180d877fe5e244b844a3020 548 SUPERFAMILY SSF53850 43 543 5.1E-133 T 14-10-2018 TSH58p_30630 09923210b180d877fe5e244b844a3020 548 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 90 455 3.0E-92 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain TSH58p_30630 09923210b180d877fe5e244b844a3020 548 Gene3D G3DSA:3.40.190.10 15 292 1.7E-73 T 14-10-2018 TSH58p_02170 a1f4812781dfdceac8a19e96c5c0142f 202 Gene3D G3DSA:1.10.260.40 9 66 5.0E-10 T 14-10-2018 TSH58p_02170 a1f4812781dfdceac8a19e96c5c0142f 202 SUPERFAMILY SSF47413 6 57 4.02E-7 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_24250 e7728650462e505b9e24bf8723b3d3f6 189 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 8 183 1.1E-57 T 14-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TSH58p_24250 e7728650462e505b9e24bf8723b3d3f6 189 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 13 183 2.0E-57 T 14-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TSH58p_24250 e7728650462e505b9e24bf8723b3d3f6 189 SUPERFAMILY SSF89028 6 184 6.08E-63 T 14-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TSH58p_24250 e7728650462e505b9e24bf8723b3d3f6 189 Pfam PF01923 Cobalamin adenosyltransferase 7 172 1.4E-61 T 14-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TSH58p_24250 e7728650462e505b9e24bf8723b3d3f6 189 Gene3D G3DSA:1.20.1200.10 16 187 2.0E-58 T 14-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TSH58p_15615 b0b6ceb8aab9c9a78b71d3ce77c46fd6 202 Pfam PF06055 Exopolysaccharide synthesis, ExoD 10 187 9.4E-52 T 14-10-2018 IPR010331 Exopolysaccharide synthesis, ExoD TSH58p_15615 b0b6ceb8aab9c9a78b71d3ce77c46fd6 202 PIRSF PIRSF033239 1 200 1.5E-45 T 14-10-2018 IPR010331 Exopolysaccharide synthesis, ExoD TSH58p_12620 3899f137d9fc27a08c3d606eee9c3c65 207 Gene3D G3DSA:3.30.420.10 1 163 1.2E-38 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TSH58p_12620 3899f137d9fc27a08c3d606eee9c3c65 207 SMART SM00479 2 166 2.1E-21 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TSH58p_12620 3899f137d9fc27a08c3d606eee9c3c65 207 Pfam PF00929 Exonuclease 4 153 6.8E-19 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TSH58p_12620 3899f137d9fc27a08c3d606eee9c3c65 207 SUPERFAMILY SSF53098 3 162 2.47E-41 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily TSH58p_14685 70f326806c5fdcf366fd94e5f382847d 302 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 23 300 1.6E-56 T 14-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 TSH58p_14685 70f326806c5fdcf366fd94e5f382847d 302 PIRSF PIRSF026649 13 302 6.2E-62 T 14-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 TSH58p_00570 a47c8b30149b8451b9d3eecaa98091ae 431 PRINTS PR00732 Glycosyl hydrolase family 4 signature 145 162 1.9E-24 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TSH58p_00570 a47c8b30149b8451b9d3eecaa98091ae 431 PRINTS PR00732 Glycosyl hydrolase family 4 signature 170 181 1.9E-24 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TSH58p_00570 a47c8b30149b8451b9d3eecaa98091ae 431 PRINTS PR00732 Glycosyl hydrolase family 4 signature 116 136 1.9E-24 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TSH58p_00570 a47c8b30149b8451b9d3eecaa98091ae 431 PRINTS PR00732 Glycosyl hydrolase family 4 signature 79 95 1.9E-24 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TSH58p_00570 a47c8b30149b8451b9d3eecaa98091ae 431 PRINTS PR00732 Glycosyl hydrolase family 4 signature 196 208 1.9E-24 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TSH58p_00570 a47c8b30149b8451b9d3eecaa98091ae 431 PRINTS PR00732 Glycosyl hydrolase family 4 signature 100 113 1.9E-24 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TSH58p_00570 a47c8b30149b8451b9d3eecaa98091ae 431 PRINTS PR00732 Glycosyl hydrolase family 4 signature 10 25 1.9E-24 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TSH58p_00570 a47c8b30149b8451b9d3eecaa98091ae 431 Pfam PF02056 Family 4 glycosyl hydrolase 10 189 1.1E-42 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TSH58p_00570 a47c8b30149b8451b9d3eecaa98091ae 431 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 201 406 1.8E-41 T 14-10-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 TSH58p_00570 a47c8b30149b8451b9d3eecaa98091ae 431 SUPERFAMILY SSF56327 174 427 9.71E-60 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 TSH58p_00570 a47c8b30149b8451b9d3eecaa98091ae 431 SUPERFAMILY SSF51735 8 173 3.07E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_00570 a47c8b30149b8451b9d3eecaa98091ae 431 Gene3D G3DSA:3.90.1820.20 5 426 7.5E-121 T 14-10-2018 TSH58p_05725 872d3fd12d055b891f2743a2cc3d7265 192 Gene3D G3DSA:3.30.910.20 30 192 2.0E-31 T 14-10-2018 IPR024930 Skp domain superfamily TSH58p_05725 872d3fd12d055b891f2743a2cc3d7265 192 Pfam PF03938 Outer membrane protein (OmpH-like) 16 177 6.7E-28 T 14-10-2018 IPR005632 Chaperone protein Skp GO:0051082 TSH58p_05725 872d3fd12d055b891f2743a2cc3d7265 192 SUPERFAMILY SSF111384 39 179 3.27E-26 T 14-10-2018 TSH58p_05725 872d3fd12d055b891f2743a2cc3d7265 192 SMART SM00935 17 179 4.1E-38 T 14-10-2018 IPR005632 Chaperone protein Skp GO:0051082 TSH58p_12830 244775b6d10d33297a12bb9eef9087c8 334 Gene3D G3DSA:3.40.50.300 57 236 1.8E-22 T 14-10-2018 TSH58p_12830 244775b6d10d33297a12bb9eef9087c8 334 TIGRFAM TIGR01650 PD_CobS: cobaltochelatase, CobS subunit 12 329 2.4E-186 T 14-10-2018 IPR006537 Cobaltochelatase subunit CobS KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 TSH58p_12830 244775b6d10d33297a12bb9eef9087c8 334 Pfam PF12556 Cobaltochelatase CobS subunit N terminal 16 46 2.0E-18 T 14-10-2018 IPR025865 Cobaltochelatase subunit CobS N-terminal domain KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 TSH58p_12830 244775b6d10d33297a12bb9eef9087c8 334 Pfam PF07728 AAA domain (dynein-related subfamily) 73 195 2.8E-11 T 14-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 TSH58p_12830 244775b6d10d33297a12bb9eef9087c8 334 SUPERFAMILY SSF52540 60 290 1.83E-30 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_32340 2ddb34e49c7c6553491986ffb96bb33b 98 SUPERFAMILY SSF54292 13 93 5.25E-21 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TSH58p_32340 2ddb34e49c7c6553491986ffb96bb33b 98 Gene3D G3DSA:3.10.20.440 3 97 4.2E-22 T 14-10-2018 TSH58p_32340 2ddb34e49c7c6553491986ffb96bb33b 98 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 11 91 2.9E-30 T 14-10-2018 TSH58p_06800 e2f370eafdee4218e18261f864f704b8 318 Gene3D G3DSA:3.40.50.2000 170 311 1.6E-29 T 14-10-2018 TSH58p_06800 e2f370eafdee4218e18261f864f704b8 318 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 172 279 6.2E-21 T 14-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 TSH58p_06800 e2f370eafdee4218e18261f864f704b8 318 SUPERFAMILY SSF53756 14 294 3.45E-55 T 14-10-2018 TSH58p_06800 e2f370eafdee4218e18261f864f704b8 318 Gene3D G3DSA:3.40.50.2000 10 159 1.1E-14 T 14-10-2018 TSH58p_22005 2525cab950b8dcebf6a2eb913fb9d19a 162 Pfam PF09411 Lipid A 3-O-deacylase (PagL) 68 129 5.3E-6 T 14-10-2018 IPR018550 Lipid A 3-O-deacylase-related TSH58p_13170 7572745dc6ce1851469bdad15ffc511b 309 SUPERFAMILY SSF103481 211 307 9.68E-9 T 14-10-2018 TSH58p_13170 7572745dc6ce1851469bdad15ffc511b 309 SUPERFAMILY SSF103481 57 156 7.59E-14 T 14-10-2018 TSH58p_13170 7572745dc6ce1851469bdad15ffc511b 309 Pfam PF00892 EamA-like transporter family 29 154 1.6E-17 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_13170 7572745dc6ce1851469bdad15ffc511b 309 Pfam PF00892 EamA-like transporter family 170 305 2.6E-15 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_15310 029d593c1bb33157d9578a6aa95d496f 153 Gene3D G3DSA:2.60.40.790 35 139 1.0E-21 T 14-10-2018 IPR008978 HSP20-like chaperone TSH58p_15310 029d593c1bb33157d9578a6aa95d496f 153 SUPERFAMILY SSF49764 34 138 3.84E-20 T 14-10-2018 IPR008978 HSP20-like chaperone TSH58p_15310 029d593c1bb33157d9578a6aa95d496f 153 Pfam PF00011 Hsp20/alpha crystallin family 44 138 1.4E-19 T 14-10-2018 IPR002068 Alpha crystallin/Hsp20 domain TSH58p_30880 0ea493355f3abd81ff40b00e04326644 302 Gene3D G3DSA:3.60.130.10 24 301 8.0E-80 T 14-10-2018 TSH58p_30880 0ea493355f3abd81ff40b00e04326644 302 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 29 292 7.8E-58 T 14-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 TSH58p_30880 0ea493355f3abd81ff40b00e04326644 302 SUPERFAMILY SSF51197 27 293 1.28E-77 T 14-10-2018 TSH58p_32030 fab4f9e6daa1e88f62cece72e5499d88 269 Pfam PF07728 AAA domain (dynein-related subfamily) 36 170 1.9E-37 T 14-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 TSH58p_32030 fab4f9e6daa1e88f62cece72e5499d88 269 Gene3D G3DSA:3.40.50.300 21 188 2.4E-30 T 14-10-2018 TSH58p_32030 fab4f9e6daa1e88f62cece72e5499d88 269 SUPERFAMILY SSF52540 30 230 5.21E-32 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_32030 fab4f9e6daa1e88f62cece72e5499d88 269 Pfam PF08406 CbbQ/NirQ/NorQ C-terminal 183 265 1.7E-29 T 14-10-2018 IPR013615 CbbQ/NirQ/NorQ, C-terminal TSH58p_00675 6e151e6936455ab023bcc81266c78059 287 Gene3D G3DSA:2.70.98.10 3 287 3.9E-86 T 14-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 TSH58p_00675 6e151e6936455ab023bcc81266c78059 287 SUPERFAMILY SSF74650 2 285 6.28E-49 T 14-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 TSH58p_00675 6e151e6936455ab023bcc81266c78059 287 Pfam PF01263 Aldose 1-epimerase 3 255 7.7E-29 T 14-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 TSH58p_16830 cbdc6dc965215e467bd734627a34bdba 232 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 24 161 3.4E-23 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ TSH58p_03675 a3f23e20238ceda87944b413b30c1752 242 SUPERFAMILY SSF55729 47 196 1.02E-5 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_13360 f59ed544b42e1c23c8aa1b9c220abc3d 141 Pfam PF13430 Domain of unknown function (DUF4112) 31 133 1.6E-30 T 14-10-2018 IPR025187 Protein of unknown function DUF4112 TSH58p_01015 3dc7a6eb2e5a5fdc06df969125823313 149 Gene3D G3DSA:3.10.129.10 1 144 2.7E-48 T 14-10-2018 TSH58p_01015 3dc7a6eb2e5a5fdc06df969125823313 149 Pfam PF01575 MaoC like domain 16 122 2.2E-26 T 14-10-2018 IPR002539 MaoC-like dehydratase domain TSH58p_01015 3dc7a6eb2e5a5fdc06df969125823313 149 SUPERFAMILY SSF54637 4 146 4.93E-41 T 14-10-2018 IPR029069 HotDog domain superfamily TSH58p_16100 88dc952370d7bed8c491b1f4144ed2b1 694 Pfam PF13899 Thioredoxin-like 583 664 1.8E-10 T 14-10-2018 TSH58p_16100 88dc952370d7bed8c491b1f4144ed2b1 694 Pfam PF11412 Disulphide bond corrector protein DsbC 51 150 2.7E-17 T 14-10-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain TSH58p_16100 88dc952370d7bed8c491b1f4144ed2b1 694 Gene3D G3DSA:3.40.30.10 569 685 2.0E-10 T 14-10-2018 TSH58p_16100 88dc952370d7bed8c491b1f4144ed2b1 694 SUPERFAMILY SSF52833 577 686 1.41E-12 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_05445 b4944eb0ba68b5d9c8a9b37aae94b8af 74 Pfam PF10073 Uncharacterized protein conserved in bacteria (DUF2312) 1 62 5.1E-17 T 14-10-2018 IPR018753 Azospirillum phage Cd, Gp10 TSH58p_22185 200cc2b1f9fea3e0334da06e2600f8f3 142 SMART SM00530 25 80 1.1E-16 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_22185 200cc2b1f9fea3e0334da06e2600f8f3 142 SUPERFAMILY SSF47413 19 83 2.06E-18 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_22185 200cc2b1f9fea3e0334da06e2600f8f3 142 Gene3D G3DSA:1.10.260.40 6 86 4.5E-20 T 14-10-2018 TSH58p_22185 200cc2b1f9fea3e0334da06e2600f8f3 142 Pfam PF01381 Helix-turn-helix 26 78 3.6E-15 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_26245 cd5f68cf6495d551baaa7376e4b4c890 348 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 5 302 4.3E-123 T 14-10-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 TSH58p_26245 cd5f68cf6495d551baaa7376e4b4c890 348 Pfam PF03741 Integral membrane protein TerC family 69 271 3.4E-59 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 TSH58p_27065 486861a3e6301e1d244a91d2efb99e1f 467 Pfam PF13372 Alginate export 71 454 1.4E-84 T 14-10-2018 IPR025388 Alginate export domain TSH58p_19620 ae930970132976df636336b9652c3c2d 244 SMART SM00382 38 221 5.9E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_19620 ae930970132976df636336b9652c3c2d 244 Gene3D G3DSA:3.40.50.300 9 244 6.9E-65 T 14-10-2018 TSH58p_19620 ae930970132976df636336b9652c3c2d 244 SUPERFAMILY SSF52540 13 242 5.65E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_19620 ae930970132976df636336b9652c3c2d 244 Pfam PF00005 ABC transporter 29 172 1.2E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_19620 ae930970132976df636336b9652c3c2d 244 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 243 1.3E-4 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSH58p_19620 ae930970132976df636336b9652c3c2d 244 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_05310 af1449dfd8107ecc5823d3fac20109aa 272 Gene3D G3DSA:3.90.226.10 17 214 4.7E-67 T 14-10-2018 TSH58p_05310 af1449dfd8107ecc5823d3fac20109aa 272 SUPERFAMILY SSF52096 19 271 1.72E-81 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_05310 af1449dfd8107ecc5823d3fac20109aa 272 Pfam PF00378 Enoyl-CoA hydratase/isomerase 24 271 1.5E-59 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TSH58p_05310 af1449dfd8107ecc5823d3fac20109aa 272 Gene3D G3DSA:1.10.12.10 217 272 1.6E-24 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal TSH58p_05820 5d90fc9ae4ff127fe5eb2e6feb9bbee6 199 Pfam PF03352 Methyladenine glycosylase 17 121 1.4E-41 T 14-10-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 TSH58p_05820 5d90fc9ae4ff127fe5eb2e6feb9bbee6 199 Gene3D G3DSA:1.10.340.30 3 166 3.0E-44 T 14-10-2018 TSH58p_05820 5d90fc9ae4ff127fe5eb2e6feb9bbee6 199 SUPERFAMILY SSF48150 4 169 2.47E-54 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TSH58p_10985 a8808a0ff6a8ebda74f879e34c7b0f95 197 Gene3D G3DSA:3.30.160.150 59 197 2.2E-36 T 14-10-2018 TSH58p_10985 a8808a0ff6a8ebda74f879e34c7b0f95 197 Pfam PF04390 Lipopolysaccharide-assembly 69 188 9.8E-8 T 14-10-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 TSH58p_13960 19ed7fbd3dcedff48a272192cb50587a 187 Gene3D G3DSA:3.30.40.60 70 160 5.8E-23 T 14-10-2018 TSH58p_13960 19ed7fbd3dcedff48a272192cb50587a 187 SMART SM00507 79 132 1.9E-10 T 14-10-2018 IPR003615 HNH nuclease TSH58p_13960 19ed7fbd3dcedff48a272192cb50587a 187 Pfam PF14279 HNH endonuclease 92 142 1.1E-18 T 14-10-2018 IPR029471 HNH endonuclease 5 TSH58p_26155 0f51fb9da34c49611e0ba48c422a9cf7 340 Gene3D G3DSA:1.10.3720.10 137 330 2.7E-18 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_26155 0f51fb9da34c49611e0ba48c422a9cf7 340 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 161 325 3.1E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_26155 0f51fb9da34c49611e0ba48c422a9cf7 340 SUPERFAMILY SSF161098 136 316 8.37E-23 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_27960 5d7a1a2f6931ae7812744a0861507a26 253 SUPERFAMILY SSF53300 45 238 9.35E-22 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TSH58p_27960 5d7a1a2f6931ae7812744a0861507a26 253 Pfam PF06707 Protein of unknown function (DUF1194) 45 240 3.0E-54 T 14-10-2018 IPR010607 Protein of unknown function DUF1194 TSH58p_27960 5d7a1a2f6931ae7812744a0861507a26 253 Gene3D G3DSA:3.40.50.410 48 246 5.2E-13 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TSH58p_31660 405cb789326fefbf2f6159733cd45d4a 279 SUPERFAMILY SSF161098 76 268 4.58E-36 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_31660 405cb789326fefbf2f6159733cd45d4a 279 Gene3D G3DSA:1.10.3720.10 75 272 5.1E-28 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_31660 405cb789326fefbf2f6159733cd45d4a 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 270 9.7E-25 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_06295 abccb69ab8bc2fd5e4c59f49d838d747 288 Gene3D G3DSA:3.40.50.720 9 171 6.2E-39 T 14-10-2018 TSH58p_06295 abccb69ab8bc2fd5e4c59f49d838d747 288 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 173 217 1.0E-11 T 14-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 TSH58p_06295 abccb69ab8bc2fd5e4c59f49d838d747 288 Gene3D G3DSA:1.10.1040.10 224 281 3.4E-7 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSH58p_06295 abccb69ab8bc2fd5e4c59f49d838d747 288 PIRSF PIRSF000103 7 225 4.4E-41 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 TSH58p_06295 abccb69ab8bc2fd5e4c59f49d838d747 288 PIRSF PIRSF000103 219 285 0.012 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 TSH58p_06295 abccb69ab8bc2fd5e4c59f49d838d747 288 SUPERFAMILY SSF48179 171 280 4.99E-21 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSH58p_06295 abccb69ab8bc2fd5e4c59f49d838d747 288 SUPERFAMILY SSF51735 10 169 3.0E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_06295 abccb69ab8bc2fd5e4c59f49d838d747 288 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 12 166 6.3E-31 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 TSH58p_06295 abccb69ab8bc2fd5e4c59f49d838d747 288 Gene3D G3DSA:1.10.1040.10 173 223 1.9E-11 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSH58p_00835 f27d2ee562be7659835b8aae1aa062bc 194 PIRSF PIRSF002721 52 192 5.1E-28 T 14-10-2018 IPR016364 Surface antigen, Rickettsia type TSH58p_00835 f27d2ee562be7659835b8aae1aa062bc 194 PIRSF PIRSF002721 14 85 0.0017 T 14-10-2018 IPR016364 Surface antigen, Rickettsia type TSH58p_00835 f27d2ee562be7659835b8aae1aa062bc 194 Pfam PF05433 Glycine zipper 2TM domain 65 103 9.1E-6 T 14-10-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 TSH58p_00835 f27d2ee562be7659835b8aae1aa062bc 194 Pfam PF16998 17 kDa outer membrane surface antigen 113 191 7.8E-7 T 14-10-2018 IPR032635 Surface antigen domain TSH58p_30290 104b37fd563b5369847cdf055462101a 170 Pfam PF10006 Uncharacterized conserved protein (DUF2249) 13 82 5.3E-25 T 14-10-2018 IPR018720 Domain of unknown function DUF2249 TSH58p_04665 c173b22d1499395e788b6749f2d38320 384 Gene3D G3DSA:3.40.50.1820 37 194 5.2E-13 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_04665 c173b22d1499395e788b6749f2d38320 384 SUPERFAMILY SSF53474 43 181 1.4E-13 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_05215 211c63089ca4dd2b86e8bd101d171996 433 Gene3D G3DSA:1.20.1250.20 11 419 7.7E-46 T 14-10-2018 TSH58p_05215 211c63089ca4dd2b86e8bd101d171996 433 SUPERFAMILY SSF103473 12 417 8.37E-53 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_05215 211c63089ca4dd2b86e8bd101d171996 433 Pfam PF07690 Major Facilitator Superfamily 280 416 3.4E-11 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_05215 211c63089ca4dd2b86e8bd101d171996 433 Pfam PF07690 Major Facilitator Superfamily 25 274 1.7E-23 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_05215 211c63089ca4dd2b86e8bd101d171996 433 TIGRFAM TIGR04259 oxa_formateAnti: oxalate/formate antiporter 16 419 4.9E-200 T 14-10-2018 IPR026355 Oxalate/formate antiporter GO:0016021|GO:0019531|GO:0019532 TSH58p_21305 e908897627eecb2a3c31352195baa98c 379 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 66 309 7.7E-73 T 14-10-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 TSH58p_21305 e908897627eecb2a3c31352195baa98c 379 Gene3D G3DSA:3.40.50.12710 2 376 6.0E-112 T 14-10-2018 IPR038375 Protein arginine methyltransferase NDUFAF7 superfamily Reactome: R-HSA-6799198 TSH58p_21305 e908897627eecb2a3c31352195baa98c 379 SUPERFAMILY SSF53335 8 373 1.17E-110 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_19505 935482a4cdc9a145e80fd6da9d992cd9 245 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 219 241 5.7E-8 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSH58p_19505 935482a4cdc9a145e80fd6da9d992cd9 245 SUPERFAMILY SSF52540 2 241 5.43E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_19505 935482a4cdc9a145e80fd6da9d992cd9 245 SMART SM00382 18 218 2.6E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_19505 935482a4cdc9a145e80fd6da9d992cd9 245 Pfam PF00005 ABC transporter 10 169 1.8E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_19505 935482a4cdc9a145e80fd6da9d992cd9 245 Gene3D G3DSA:3.40.50.300 1 244 1.0E-57 T 14-10-2018 TSH58p_15545 2d14a21bdc242ce1fb14da258b95afdb 332 SUPERFAMILY SSF53686 40 324 2.49E-81 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TSH58p_15545 2d14a21bdc242ce1fb14da258b95afdb 332 Gene3D G3DSA:3.40.50.1100 47 321 1.3E-90 T 14-10-2018 TSH58p_15545 2d14a21bdc242ce1fb14da258b95afdb 332 Gene3D G3DSA:3.40.50.1100 80 176 1.3E-90 T 14-10-2018 TSH58p_15545 2d14a21bdc242ce1fb14da258b95afdb 332 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 52 317 1.8E-68 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TSH58p_30900 0ac92902535ae29db36e802d4cd57be9 289 Gene3D G3DSA:3.60.130.10 6 289 2.3E-82 T 14-10-2018 TSH58p_30900 0ac92902535ae29db36e802d4cd57be9 289 SUPERFAMILY SSF51197 14 287 3.89E-79 T 14-10-2018 TSH58p_30900 0ac92902535ae29db36e802d4cd57be9 289 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 17 282 3.3E-61 T 14-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 TSH58p_02415 b52eef967aa886c30077afcd230b5d08 231 Gene3D G3DSA:1.20.1270.180 22 110 4.0E-7 T 14-10-2018 TSH58p_02415 b52eef967aa886c30077afcd230b5d08 231 Pfam PF07007 Lysozyme inhibitor LprI 30 102 2.6E-7 T 14-10-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal TSH58p_10455 75262c5c345da8412a280783e6143d79 286 SUPERFAMILY SSF161098 75 265 2.49E-24 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_10455 75262c5c345da8412a280783e6143d79 286 Gene3D G3DSA:1.10.3720.10 68 283 1.4E-19 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_10455 75262c5c345da8412a280783e6143d79 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 281 3.9E-23 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_10765 6a27c400fcc37fa6278dd196700e0558 159 Gene3D G3DSA:3.10.450.50 1 159 2.7E-49 T 14-10-2018 TSH58p_10765 6a27c400fcc37fa6278dd196700e0558 159 SUPERFAMILY SSF103642 138 158 2.29E-8 T 14-10-2018 TSH58p_10765 6a27c400fcc37fa6278dd196700e0558 159 Pfam PF02810 SEC-C motif 141 159 2.0E-10 T 14-10-2018 IPR004027 SEC-C motif TSH58p_10765 6a27c400fcc37fa6278dd196700e0558 159 SUPERFAMILY SSF54427 25 127 9.51E-32 T 14-10-2018 IPR032710 NTF2-like domain superfamily TSH58p_28185 12ab6d6f59d11403d8539cd53684062d 392 Pfam PF01266 FAD dependent oxidoreductase 6 361 1.7E-57 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TSH58p_28185 12ab6d6f59d11403d8539cd53684062d 392 SUPERFAMILY SSF51905 5 381 3.63E-47 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_28185 12ab6d6f59d11403d8539cd53684062d 392 Gene3D G3DSA:3.50.50.60 5 362 5.5E-102 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_28185 12ab6d6f59d11403d8539cd53684062d 392 Gene3D G3DSA:3.30.9.10 94 320 5.5E-102 T 14-10-2018 TSH58p_05540 89d7c6619c3cd1856d32bad6be00f88e 26 Pfam PF08042 PqqA family 3 21 3.2E-8 T 14-10-2018 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 TSH58p_05540 89d7c6619c3cd1856d32bad6be00f88e 26 TIGRFAM TIGR02107 PQQ_syn_pqqA: coenzyme PQQ precursor peptide PqqA 4 24 1.5E-7 T 14-10-2018 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 TSH58p_22070 c2a47793654a255e3516f9990c680925 111 TIGRFAM TIGR02222 chap_CsaA: export-related chaperone protein CsaA 5 110 1.6E-45 T 14-10-2018 IPR008231 Probable chaperone CsaA TSH58p_22070 c2a47793654a255e3516f9990c680925 111 Pfam PF01588 Putative tRNA binding domain 13 107 2.3E-13 T 14-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 TSH58p_22070 c2a47793654a255e3516f9990c680925 111 SUPERFAMILY SSF50249 2 110 8.57E-33 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_22070 c2a47793654a255e3516f9990c680925 111 Gene3D G3DSA:2.40.50.140 1 111 4.0E-34 T 14-10-2018 TSH58p_14000 14dca6cb317a9b053915c78431c2df20 410 SUPERFAMILY SSF55073 219 404 2.67E-44 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_14000 14dca6cb317a9b053915c78431c2df20 410 Gene3D G3DSA:3.30.70.1230 218 407 9.8E-41 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_14000 14dca6cb317a9b053915c78431c2df20 410 SMART SM00044 187 386 1.8E-4 T 14-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 TSH58p_14000 14dca6cb317a9b053915c78431c2df20 410 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 225 394 2.3E-17 T 14-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 TSH58p_24560 fc27e4fc17314a9242af49a0108397c2 593 SUPERFAMILY SSF116726 214 294 1.18E-16 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSH58p_24560 fc27e4fc17314a9242af49a0108397c2 593 Gene3D G3DSA:3.30.70.1450 216 292 9.3E-13 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSH58p_24560 fc27e4fc17314a9242af49a0108397c2 593 Gene3D G3DSA:3.30.70.1450 306 381 1.5E-12 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSH58p_24560 fc27e4fc17314a9242af49a0108397c2 593 Pfam PF03600 Citrate transporter 16 537 5.0E-44 T 14-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 TSH58p_24560 fc27e4fc17314a9242af49a0108397c2 593 SUPERFAMILY SSF116726 299 387 3.14E-16 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSH58p_24560 fc27e4fc17314a9242af49a0108397c2 593 Pfam PF02080 TrkA-C domain 221 285 2.6E-11 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TSH58p_24560 fc27e4fc17314a9242af49a0108397c2 593 Pfam PF02080 TrkA-C domain 311 380 7.1E-9 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TSH58p_25395 9f51a4a716937c6b0686d38564d84970 272 Gene3D G3DSA:1.10.10.10 40 101 2.9E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_25395 9f51a4a716937c6b0686d38564d84970 272 SUPERFAMILY SSF46785 41 98 5.3E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_25395 9f51a4a716937c6b0686d38564d84970 272 SMART SM00345 44 107 0.0013 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_25395 9f51a4a716937c6b0686d38564d84970 272 SMART SM00895 117 241 7.2E-20 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_25395 9f51a4a716937c6b0686d38564d84970 272 Pfam PF00392 Bacterial regulatory proteins, gntR family 41 96 8.1E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSH58p_25395 9f51a4a716937c6b0686d38564d84970 272 SUPERFAMILY SSF48008 117 248 1.54E-28 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_25395 9f51a4a716937c6b0686d38564d84970 272 Gene3D G3DSA:1.20.120.530 113 251 2.2E-28 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSH58p_25395 9f51a4a716937c6b0686d38564d84970 272 Pfam PF07729 FCD domain 120 240 2.4E-27 T 14-10-2018 IPR011711 GntR, C-terminal TSH58p_00265 75bc77b8dbdea8ee796b86109fa6ccde 508 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 439 9.2E-137 T 14-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane TSH58p_01360 11dffeff0ce6551b1000089f2c156173 138 SUPERFAMILY SSF50249 4 129 5.14E-38 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_01360 11dffeff0ce6551b1000089f2c156173 138 Gene3D G3DSA:1.10.12.20 12 56 3.5E-6 T 14-10-2018 TSH58p_01360 11dffeff0ce6551b1000089f2c156173 138 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 60 121 3.5E-22 T 14-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal TSH58p_01360 11dffeff0ce6551b1000089f2c156173 138 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 20 53 1.6E-14 T 14-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal TSH58p_04755 4b50c2b38ccae7e7149f17806867a361 544 SUPERFAMILY SSF117457 364 539 5.49E-61 T 14-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 TSH58p_04755 4b50c2b38ccae7e7149f17806867a361 544 Pfam PF05681 Fumarate hydratase (Fumerase) 54 328 2.5E-83 T 14-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 TSH58p_04755 4b50c2b38ccae7e7149f17806867a361 544 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 376 540 1.1E-54 T 14-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 TSH58p_04755 4b50c2b38ccae7e7149f17806867a361 544 Pfam PF05683 Fumarase C-terminus 335 540 1.8E-92 T 14-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 TSH58p_04755 4b50c2b38ccae7e7149f17806867a361 544 Gene3D G3DSA:3.20.130.10 354 540 5.8E-58 T 14-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 TSH58p_04755 4b50c2b38ccae7e7149f17806867a361 544 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 71 329 1.4E-29 T 14-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 TSH58p_04755 4b50c2b38ccae7e7149f17806867a361 544 PIRSF PIRSF001394 33 544 2.5E-221 T 14-10-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 TSH58p_04755 4b50c2b38ccae7e7149f17806867a361 544 ProSitePatterns PS00163 Fumarate lyases signature. 459 468 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 TSH58p_23530 e06e35a7a9e37ab8cf3631ddf5752e1f 433 Pfam PF00375 Sodium:dicarboxylate symporter family 16 408 1.7E-109 T 14-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 TSH58p_23530 e06e35a7a9e37ab8cf3631ddf5752e1f 433 SUPERFAMILY SSF118215 16 409 1.12E-119 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 TSH58p_23530 e06e35a7a9e37ab8cf3631ddf5752e1f 433 PRINTS PR00173 Glutamate-aspartate symporter signature 334 353 3.2E-25 T 14-10-2018 TSH58p_23530 e06e35a7a9e37ab8cf3631ddf5752e1f 433 PRINTS PR00173 Glutamate-aspartate symporter signature 299 325 3.2E-25 T 14-10-2018 TSH58p_23530 e06e35a7a9e37ab8cf3631ddf5752e1f 433 PRINTS PR00173 Glutamate-aspartate symporter signature 152 174 3.2E-25 T 14-10-2018 TSH58p_23530 e06e35a7a9e37ab8cf3631ddf5752e1f 433 PRINTS PR00173 Glutamate-aspartate symporter signature 81 106 3.2E-25 T 14-10-2018 TSH58p_23530 e06e35a7a9e37ab8cf3631ddf5752e1f 433 PRINTS PR00173 Glutamate-aspartate symporter signature 14 34 3.2E-25 T 14-10-2018 TSH58p_23530 e06e35a7a9e37ab8cf3631ddf5752e1f 433 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 302 325 - T 14-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site TSH58p_23530 e06e35a7a9e37ab8cf3631ddf5752e1f 433 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 43 58 - T 14-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site TSH58p_23530 e06e35a7a9e37ab8cf3631ddf5752e1f 433 Gene3D G3DSA:1.10.3860.10 5 427 1.1E-126 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 TSH58p_15045 b5e88880d1db1c2a680cabd71d2b3637 284 SUPERFAMILY SSF53335 91 140 3.45E-11 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_15045 b5e88880d1db1c2a680cabd71d2b3637 284 Pfam PF13489 Methyltransferase domain 26 181 4.4E-10 T 14-10-2018 TSH58p_15045 b5e88880d1db1c2a680cabd71d2b3637 284 Gene3D G3DSA:3.40.50.150 28 232 1.6E-9 T 14-10-2018 TSH58p_11835 3ed73c078082daa5be1139264350c428 243 Pfam PF03741 Integral membrane protein TerC family 15 203 1.7E-48 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 TSH58p_23195 83230ebaa13d9af4f07348dbbea93add 94 SMART SM00857 11 94 2.7E-5 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 TSH58p_23195 83230ebaa13d9af4f07348dbbea93add 94 SUPERFAMILY SSF53041 10 80 4.19E-17 T 14-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 TSH58p_23195 83230ebaa13d9af4f07348dbbea93add 94 Pfam PF00239 Resolvase, N terminal domain 11 81 1.9E-18 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 TSH58p_23195 83230ebaa13d9af4f07348dbbea93add 94 Gene3D G3DSA:3.40.50.1390 8 83 8.8E-23 T 14-10-2018 TSH58p_07695 0a2ca4d983074db590420d0a0b0cc1ad 196 Pfam PF04891 NifQ 36 193 9.4E-42 T 14-10-2018 IPR006975 NifQ GO:0009399|GO:0030151 TSH58p_22010 2dfacfc0586cd8d8c1d37492039ee66e 180 Pfam PF07309 Flagellar protein FlaF 42 135 2.3E-13 T 14-10-2018 IPR010845 Flagellar FlaF GO:0044781 TSH58p_22010 2dfacfc0586cd8d8c1d37492039ee66e 180 Pfam PF11154 Protein of unknown function (DUF2934) 141 174 3.1E-16 T 14-10-2018 IPR021327 Protein of unknown function DUF2934 TSH58p_06010 a7b484ad745b47ebdd200f316fe9f053 82 Pfam PF06568 Domain of unknown function (DUF1127) 44 71 3.3E-12 T 14-10-2018 IPR009506 Protein of unknown function DUF1127 TSH58p_29350 fd1fe34eecac74e1cd4271c0eb2c9633 318 SUPERFAMILY SSF103481 201 300 1.07E-9 T 14-10-2018 TSH58p_29350 fd1fe34eecac74e1cd4271c0eb2c9633 318 Pfam PF00892 EamA-like transporter family 160 296 5.8E-19 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_29350 fd1fe34eecac74e1cd4271c0eb2c9633 318 Pfam PF00892 EamA-like transporter family 12 146 3.5E-24 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_29350 fd1fe34eecac74e1cd4271c0eb2c9633 318 SUPERFAMILY SSF103481 45 148 1.03E-17 T 14-10-2018 TSH58p_01020 7fae6c3556c42d4d3d4064636d802494 133 SUPERFAMILY SSF50249 3 121 2.06E-25 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_01020 7fae6c3556c42d4d3d4064636d802494 133 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 55 116 2.2E-16 T 14-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal TSH58p_01020 7fae6c3556c42d4d3d4064636d802494 133 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 18 50 9.6E-12 T 14-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal TSH58p_32570 fe921baf4e25dcde5c2a5a321f7c830b 280 Gene3D G3DSA:3.40.830.10 1 280 1.2E-89 T 14-10-2018 TSH58p_32570 fe921baf4e25dcde5c2a5a321f7c830b 280 SUPERFAMILY SSF53213 2 277 1.96E-96 T 14-10-2018 TSH58p_32570 fe921baf4e25dcde5c2a5a321f7c830b 280 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 8 270 7.5E-64 T 14-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 TSH58p_19500 955ce4f44bf84c445aecc092538fc203 323 Pfam PF02653 Branched-chain amino acid transport system / permease component 27 291 2.8E-46 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_08010 2008d8a1410b74ca40dbe2ad29142249 231 SUPERFAMILY SSF161098 17 223 8.9E-30 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_08010 2008d8a1410b74ca40dbe2ad29142249 231 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 44 225 3.0E-9 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_08010 2008d8a1410b74ca40dbe2ad29142249 231 Gene3D G3DSA:1.10.3720.10 3 230 9.1E-27 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_09490 9da06a6a2603de807b699b63f42d88bc 106 Pfam PF10685 Stress-induced bacterial acidophilic repeat motif 22 42 1.3E-7 T 14-10-2018 IPR019626 Stress-induced protein, KGG, repeat TSH58p_09490 9da06a6a2603de807b699b63f42d88bc 106 Pfam PF10685 Stress-induced bacterial acidophilic repeat motif 73 93 2.0E-7 T 14-10-2018 IPR019626 Stress-induced protein, KGG, repeat TSH58p_09490 9da06a6a2603de807b699b63f42d88bc 106 Pfam PF10685 Stress-induced bacterial acidophilic repeat motif 48 67 2.7E-7 T 14-10-2018 IPR019626 Stress-induced protein, KGG, repeat TSH58p_06400 2a3c59fba5df0f0bb8caab1c107072db 294 Pfam PF02653 Branched-chain amino acid transport system / permease component 7 279 2.1E-35 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_05205 f55f8bed2c391155b3f24b3402e73152 160 Pfam PF00583 Acetyltransferase (GNAT) family 56 145 4.7E-10 T 14-10-2018 IPR000182 GNAT domain TSH58p_05205 f55f8bed2c391155b3f24b3402e73152 160 Gene3D G3DSA:3.40.630.30 18 153 3.4E-19 T 14-10-2018 TSH58p_05205 f55f8bed2c391155b3f24b3402e73152 160 SUPERFAMILY SSF55729 21 145 4.36E-18 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_11720 4eb4a37e601c631ea023ceadc1495e70 269 SUPERFAMILY SSF89260 25 89 1.22E-5 T 14-10-2018 TSH58p_11720 4eb4a37e601c631ea023ceadc1495e70 269 Gene3D G3DSA:2.60.120.380 7 109 2.3E-7 T 14-10-2018 TSH58p_28375 04850c936155ec68b60013e433340194 353 Pfam PF01594 AI-2E family transporter 14 334 7.4E-67 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like TSH58p_15920 d4ab2499b57b62904e93348322408b44 463 Pfam PF02386 Cation transport protein 23 456 1.7E-50 T 14-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 TSH58p_15920 d4ab2499b57b62904e93348322408b44 463 PIRSF PIRSF006247 1 463 7.3E-147 T 14-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 TSH58p_19675 7c04dafc1ad2efb50a69633704b59f67 332 Pfam PF01515 Phosphate acetyl/butaryl transferase 87 301 6.0E-35 T 14-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 TSH58p_19675 7c04dafc1ad2efb50a69633704b59f67 332 SUPERFAMILY SSF53659 20 305 2.3E-60 T 14-10-2018 TSH58p_19675 7c04dafc1ad2efb50a69633704b59f67 332 Gene3D G3DSA:3.40.718.10 10 305 8.2E-85 T 14-10-2018 TSH58p_19675 7c04dafc1ad2efb50a69633704b59f67 332 PIRSF PIRSF000428 11 309 6.5E-73 T 14-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 TSH58p_16735 a71b2162b91410795d378fec40f34796 441 Pfam PF00929 Exonuclease 260 391 9.6E-5 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TSH58p_16735 a71b2162b91410795d378fec40f34796 441 SMART SM00479 246 419 5.1E-5 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TSH58p_16735 a71b2162b91410795d378fec40f34796 441 SUPERFAMILY SSF53098 259 418 1.94E-17 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily TSH58p_16735 a71b2162b91410795d378fec40f34796 441 SUPERFAMILY SSF55785 116 196 4.45E-8 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_16735 a71b2162b91410795d378fec40f34796 441 Gene3D G3DSA:3.30.420.10 253 420 1.1E-17 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TSH58p_12140 907930a7818968d16e8c57f9fe8d3310 305 Pfam PF14338 Mrr N-terminal domain 6 91 4.9E-28 T 14-10-2018 IPR025745 Restriction system protein Mrr-like N-terminal domain TSH58p_12140 907930a7818968d16e8c57f9fe8d3310 305 SUPERFAMILY SSF52980 163 282 4.61E-15 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TSH58p_12140 907930a7818968d16e8c57f9fe8d3310 305 Gene3D G3DSA:3.40.91.100 137 300 9.5E-8 T 14-10-2018 TSH58p_12140 907930a7818968d16e8c57f9fe8d3310 305 Pfam PF04471 Restriction endonuclease 160 281 9.8E-32 T 14-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 TSH58p_01305 e082ee4559e1bc0afdb8758f3ba784eb 407 Pfam PF06779 Uncharacterised MFS-type transporter YbfB 29 392 8.9E-76 T 14-10-2018 IPR010645 Uncharacterised MFS-type transporter YbfB TSH58p_01305 e082ee4559e1bc0afdb8758f3ba784eb 407 Gene3D G3DSA:1.20.1250.20 17 393 8.4E-24 T 14-10-2018 TSH58p_01305 e082ee4559e1bc0afdb8758f3ba784eb 407 SUPERFAMILY SSF103473 15 405 3.66E-37 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_30970 bf2a49ba8a72286548a7c7c4eb52b0e0 329 Gene3D G3DSA:3.40.190.10 45 327 1.0E-54 T 14-10-2018 TSH58p_30970 bf2a49ba8a72286548a7c7c4eb52b0e0 329 PIRSF PIRSF027386 1 329 5.4E-85 T 14-10-2018 IPR027024 ABC-type uncharacterised transport system, substrate-binding component, TM0202 type TSH58p_30970 bf2a49ba8a72286548a7c7c4eb52b0e0 329 Gene3D G3DSA:3.40.190.10 113 227 1.0E-54 T 14-10-2018 TSH58p_30970 bf2a49ba8a72286548a7c7c4eb52b0e0 329 SUPERFAMILY SSF53850 47 327 5.79E-29 T 14-10-2018 TSH58p_30970 bf2a49ba8a72286548a7c7c4eb52b0e0 329 Pfam PF13379 NMT1-like family 129 273 7.8E-12 T 14-10-2018 TSH58p_31190 7e0de707c53a02c6bf06def692b32a33 296 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 251 4.4E-33 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_01755 54512931ceda4cdee7cadc75a295eb22 357 Gene3D G3DSA:3.40.190.10 42 354 3.6E-115 T 14-10-2018 TSH58p_01755 54512931ceda4cdee7cadc75a295eb22 357 Gene3D G3DSA:3.40.190.10 142 264 3.6E-115 T 14-10-2018 TSH58p_01755 54512931ceda4cdee7cadc75a295eb22 357 Pfam PF13416 Bacterial extracellular solute-binding protein 59 323 1.4E-35 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSH58p_01755 54512931ceda4cdee7cadc75a295eb22 357 SUPERFAMILY SSF53850 39 354 8.98E-61 T 14-10-2018 TSH58p_13230 06238ed26675afefc881e63362b53b46 486 Pfam PF02646 RmuC family 159 446 1.7E-92 T 14-10-2018 IPR003798 DNA recombination RmuC TSH58p_23140 ecd826b411a97b2682145ad593c0939c 248 Pfam PF13408 Recombinase zinc beta ribbon domain 26 78 8.9E-9 T 14-10-2018 IPR025827 Recombinase zinc beta ribbon domain TSH58p_07690 081715e066e5980e9ea2bc4cf8bbaa4c 97 Pfam PF13237 4Fe-4S dicluster domain 23 85 3.8E-6 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_07690 081715e066e5980e9ea2bc4cf8bbaa4c 97 SUPERFAMILY SSF54862 13 94 2.26E-13 T 14-10-2018 TSH58p_07690 081715e066e5980e9ea2bc4cf8bbaa4c 97 Gene3D G3DSA:3.30.70.20 3 97 6.8E-12 T 14-10-2018 TSH58p_07690 081715e066e5980e9ea2bc4cf8bbaa4c 97 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 28 39 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_07690 081715e066e5980e9ea2bc4cf8bbaa4c 97 TIGRFAM TIGR02936 fdxN_nitrog: ferredoxin III, nif-specific 6 94 2.5E-40 T 14-10-2018 IPR014283 Ferredoxin III 4[4Fe-4S], nif-specific TSH58p_29340 80623508cd37cfbdc83279be614a6039 404 SUPERFAMILY SSF51338 3 399 6.88E-30 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_29340 80623508cd37cfbdc83279be614a6039 404 SUPERFAMILY SSF51556 60 360 1.08E-86 T 14-10-2018 IPR032466 Metal-dependent hydrolase TSH58p_29340 80623508cd37cfbdc83279be614a6039 404 TIGRFAM TIGR01224 hutI: imidazolonepropionase 22 397 1.8E-146 T 14-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 TSH58p_29340 80623508cd37cfbdc83279be614a6039 404 Pfam PF01979 Amidohydrolase family 57 398 2.8E-20 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TSH58p_29340 80623508cd37cfbdc83279be614a6039 404 Gene3D G3DSA:2.30.40.10 14 396 6.0E-164 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_29340 80623508cd37cfbdc83279be614a6039 404 Gene3D G3DSA:3.20.20.140 61 359 6.0E-164 T 14-10-2018 TSH58p_29340 80623508cd37cfbdc83279be614a6039 404 Hamap MF_00372 Imidazolonepropionase [hutI]. 4 399 43.548 T 14-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 TSH58p_26855 af81649fbea82abe0321217f175930b1 472 Gene3D G3DSA:1.20.1250.20 266 459 1.0E-20 T 14-10-2018 TSH58p_26855 af81649fbea82abe0321217f175930b1 472 SUPERFAMILY SSF103473 1 457 7.85E-64 T 14-10-2018 IPR036259 MFS transporter superfamily TSH58p_26855 af81649fbea82abe0321217f175930b1 472 PRINTS PR01036 Tetracycline resistance protein TetB signature 29 53 1.1E-6 T 14-10-2018 TSH58p_26855 af81649fbea82abe0321217f175930b1 472 PRINTS PR01036 Tetracycline resistance protein TetB signature 309 333 1.1E-6 T 14-10-2018 TSH58p_26855 af81649fbea82abe0321217f175930b1 472 PRINTS PR01036 Tetracycline resistance protein TetB signature 150 174 1.1E-6 T 14-10-2018 TSH58p_26855 af81649fbea82abe0321217f175930b1 472 PRINTS PR01036 Tetracycline resistance protein TetB signature 120 140 1.1E-6 T 14-10-2018 TSH58p_26855 af81649fbea82abe0321217f175930b1 472 Pfam PF07690 Major Facilitator Superfamily 31 416 5.1E-44 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSH58p_26855 af81649fbea82abe0321217f175930b1 472 Gene3D G3DSA:1.20.1720.10 28 253 8.3E-37 T 14-10-2018 TSH58p_14905 6acd1776201015b2ee5c1c518b3d3a77 332 SUPERFAMILY SSF53850 23 249 1.58E-36 T 14-10-2018 TSH58p_14905 6acd1776201015b2ee5c1c518b3d3a77 332 Gene3D G3DSA:3.40.190.10 29 323 7.3E-70 T 14-10-2018 TSH58p_14905 6acd1776201015b2ee5c1c518b3d3a77 332 Pfam PF09084 NMT1/THI5 like 36 248 1.5E-46 T 14-10-2018 IPR015168 SsuA/THI5-like TSH58p_14905 6acd1776201015b2ee5c1c518b3d3a77 332 Gene3D G3DSA:3.40.190.10 106 208 7.3E-70 T 14-10-2018 TSH58p_27545 c59bf4cb6125b22368d0803e5457e14e 145 Pfam PF02050 Flagellar FliJ protein 16 131 2.9E-13 T 14-10-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 TSH58p_07705 455ecdeb70c67db1658fb2a60a02c8d1 165 SUPERFAMILY SSF48452 28 148 2.6E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSH58p_24245 d5eb63a0ec10730e6d6d57f2b76ebe73 64 Pfam PF04588 Hypoxia induced protein conserved region 8 57 1.1E-9 T 14-10-2018 IPR007667 Hypoxia induced protein, domain TSH58p_24245 d5eb63a0ec10730e6d6d57f2b76ebe73 64 Pfam PF11137 Protein of unknown function (DUF2909) 7 61 1.5E-9 T 14-10-2018 IPR021313 Protein of unknown function DUF2909 TSH58p_23125 a722e9e5a1a7ded6dfb668511fccd032 413 SUPERFAMILY SSF51735 4 239 2.36E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_23125 a722e9e5a1a7ded6dfb668511fccd032 413 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 141 6.4E-9 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TSH58p_23125 a722e9e5a1a7ded6dfb668511fccd032 413 Gene3D G3DSA:3.40.50.720 2 243 7.4E-40 T 14-10-2018 TSH58p_23125 a722e9e5a1a7ded6dfb668511fccd032 413 Pfam PF13781 DoxX-like family 305 405 6.6E-20 T 14-10-2018 IPR025695 DoxX-like family TSH58p_09135 9ef6e956d2649d2b0a01a481c725d447 121 Gene3D G3DSA:3.30.70.20 1 59 7.6E-12 T 14-10-2018 TSH58p_09135 9ef6e956d2649d2b0a01a481c725d447 121 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 41 52 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_09135 9ef6e956d2649d2b0a01a481c725d447 121 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 10 21 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_09135 9ef6e956d2649d2b0a01a481c725d447 121 Pfam PF14697 4Fe-4S dicluster domain 5 55 9.3E-9 T 14-10-2018 TSH58p_09135 9ef6e956d2649d2b0a01a481c725d447 121 SUPERFAMILY SSF54862 5 61 8.6E-17 T 14-10-2018 TSH58p_13675 874d1cc28d48a620956eb4cafc201f09 272 Pfam PF03405 Fatty acid desaturase 59 171 1.6E-5 T 14-10-2018 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 TSH58p_13675 874d1cc28d48a620956eb4cafc201f09 272 Gene3D G3DSA:1.10.620.20 4 222 4.1E-19 T 14-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 TSH58p_13675 874d1cc28d48a620956eb4cafc201f09 272 SUPERFAMILY SSF47240 4 255 1.87E-45 T 14-10-2018 IPR009078 Ferritin-like superfamily TSH58p_17615 a84e60e4c1d1d76664a71b15bd112aa7 210 Pfam PF05136 Phage portal protein, lambda family 42 209 9.4E-36 T 14-10-2018 IPR006429 Phage portal protein, lambda family GO:0005198|GO:0019068 TSH58p_24760 f3bc0495ce505602fc6e5b8457dc8c8f 153 SMART SM00226 11 147 6.0E-14 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I TSH58p_24760 f3bc0495ce505602fc6e5b8457dc8c8f 153 Gene3D G3DSA:3.40.50.2300 10 146 3.3E-31 T 14-10-2018 TSH58p_24760 f3bc0495ce505602fc6e5b8457dc8c8f 153 SUPERFAMILY SSF52788 11 144 2.75E-33 T 14-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily TSH58p_24760 f3bc0495ce505602fc6e5b8457dc8c8f 153 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 13 114 3.3E-17 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I TSH58p_30580 95d384871d43c26011a3442082193595 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 42 215 1.2E-24 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_30580 95d384871d43c26011a3442082193595 218 SUPERFAMILY SSF161098 7 201 1.44E-44 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_30580 95d384871d43c26011a3442082193595 218 Gene3D G3DSA:1.10.3720.10 3 217 3.6E-50 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_24160 6683f10d9f56659e434ab17cbcd9b283 162 Pfam PF07309 Flagellar protein FlaF 12 114 1.8E-24 T 14-10-2018 IPR010845 Flagellar FlaF GO:0044781 TSH58p_25305 47022dea0ce70f6cb8f4a89442294c55 545 Pfam PF04411 PD-(D/E)XK nuclease superfamily 400 491 8.4E-11 T 14-10-2018 IPR007505 PD-(D/E)XK nuclease superfamily 7 TSH58p_06835 93b2b14e2c9d7d1eb033e274cbf1f41e 167 Pfam PF10722 Putative bacterial sensory transduction regulator 15 144 1.3E-32 T 14-10-2018 IPR019660 Putative sensory transduction regulator YbjN TSH58p_11275 e20fc7ddf430dfe1a8c364ffbeca7f7e 259 Pfam PF09608 Putative transmembrane protein (Alph_Pro_TM) 37 258 3.4E-85 T 14-10-2018 IPR019088 Conserved hypothetical protein CHP02186-related, transmembrane TSH58p_17235 5d287b32aac5092f4e54b220c9b988e3 147 Pfam PF05443 ROS/MUCR transcriptional regulator protein 14 135 1.6E-49 T 14-10-2018 IPR008807 ROSMUCR transcriptional regulator GO:0003677|GO:0006355|GO:0008270 TSH58p_17235 5d287b32aac5092f4e54b220c9b988e3 147 Gene3D G3DSA:1.10.10.1550 62 118 3.4E-30 T 14-10-2018 TSH58p_18385 e285538fa3ba025b5fdb560107a6a951 283 SUPERFAMILY SSF55729 140 267 1.72E-24 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_18385 e285538fa3ba025b5fdb560107a6a951 283 Gene3D G3DSA:3.40.630.30 109 264 5.4E-24 T 14-10-2018 TSH58p_18385 e285538fa3ba025b5fdb560107a6a951 283 Pfam PF00583 Acetyltransferase (GNAT) family 147 247 5.9E-17 T 14-10-2018 IPR000182 GNAT domain TSH58p_10555 c30916015544e9422f19ac0b2aa6fec2 236 Gene3D G3DSA:3.40.50.2020 7 234 9.1E-45 T 14-10-2018 TSH58p_10555 c30916015544e9422f19ac0b2aa6fec2 236 Pfam PF00156 Phosphoribosyl transferase domain 67 158 1.4E-6 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TSH58p_10555 c30916015544e9422f19ac0b2aa6fec2 236 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 236 18.935 T 14-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSH58p_10555 c30916015544e9422f19ac0b2aa6fec2 236 SUPERFAMILY SSF53271 16 222 1.75E-26 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like TSH58p_20060 b63488cac4f9cdcf2c5ed223e8d3ee15 89 Pfam PF11747 Killing trait 11 78 2.4E-30 T 14-10-2018 IPR021070 Killing trait, RebB TSH58p_07575 a656ee238b7e3b6b8e1206b76ec96d05 103 Pfam PF04319 NifZ domain 19 89 1.4E-23 T 14-10-2018 IPR007415 Nitrogenase MoFe maturation protein, NifZ GO:0009399 TSH58p_20280 1226cc14d11ca3dc7ae7edf4b8f563c8 227 Pfam PF08241 Methyltransferase domain 22 117 4.3E-23 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TSH58p_20280 1226cc14d11ca3dc7ae7edf4b8f563c8 227 SUPERFAMILY SSF53335 6 123 3.56E-34 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_20280 1226cc14d11ca3dc7ae7edf4b8f563c8 227 Gene3D G3DSA:3.40.50.150 3 152 2.5E-33 T 14-10-2018 TSH58p_13200 9c6a9cdc2383afddec2c0e9cf56bb2d8 443 Pfam PF02653 Branched-chain amino acid transport system / permease component 147 427 3.1E-44 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_16575 8c00b2035c7734456608f803d6bd7ba1 181 Gene3D G3DSA:1.10.10.10 16 171 1.3E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_16575 8c00b2035c7734456608f803d6bd7ba1 181 ProSitePatterns PS01117 MarR-type HTH domain signature. 94 128 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site TSH58p_16575 8c00b2035c7734456608f803d6bd7ba1 181 SUPERFAMILY SSF46785 28 171 2.24E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_16575 8c00b2035c7734456608f803d6bd7ba1 181 SMART SM00347 56 155 3.3E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_16575 8c00b2035c7734456608f803d6bd7ba1 181 Pfam PF12802 MarR family 62 118 7.8E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSH58p_07995 4a5a9f6d524780514f3fc76564ca4e18 164 Pfam PF11749 Protein of unknown function (DUF3305) 13 154 1.8E-45 T 14-10-2018 IPR021736 Protein of unknown function DUF3305 TSH58p_18305 b97627cc0e037075089a05982f76d2d9 810 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 182 325 5.0E-6 T 14-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like TSH58p_23505 ab906b9f2204d4f1a1a26faab0fb5cec 577 Pfam PF02470 MlaD protein 309 408 3.2E-16 T 14-10-2018 IPR003399 Mce/MlaD TSH58p_23505 ab906b9f2204d4f1a1a26faab0fb5cec 577 Pfam PF02470 MlaD protein 60 151 2.2E-12 T 14-10-2018 IPR003399 Mce/MlaD TSH58p_23505 ab906b9f2204d4f1a1a26faab0fb5cec 577 Pfam PF02470 MlaD protein 176 236 6.6E-8 T 14-10-2018 IPR003399 Mce/MlaD TSH58p_28685 c57cdd8e9f4108b5baf51733cc58c2f5 312 Gene3D G3DSA:3.40.50.720 19 306 2.1E-113 T 14-10-2018 TSH58p_28685 c57cdd8e9f4108b5baf51733cc58c2f5 312 Gene3D G3DSA:3.40.50.720 100 283 2.1E-113 T 14-10-2018 TSH58p_28685 c57cdd8e9f4108b5baf51733cc58c2f5 312 SUPERFAMILY SSF51735 100 281 4.56E-51 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_28685 c57cdd8e9f4108b5baf51733cc58c2f5 312 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 280 1.0E-46 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TSH58p_28685 c57cdd8e9f4108b5baf51733cc58c2f5 312 SUPERFAMILY SSF52283 1 134 8.88E-32 T 14-10-2018 TSH58p_28685 c57cdd8e9f4108b5baf51733cc58c2f5 312 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 311 2.6E-25 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 TSH58p_16595 dd2a1de806e296da093be4bc9da33db5 191 Pfam PF14347 Domain of unknown function (DUF4399) 90 180 1.2E-39 T 14-10-2018 IPR025512 Domain of unknown function DUF4399 TSH58p_02960 7eee14080abdd3ca8c40c37996db36c7 268 Gene3D G3DSA:1.10.3720.10 10 266 3.1E-47 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_02960 7eee14080abdd3ca8c40c37996db36c7 268 SUPERFAMILY SSF161098 13 258 1.78E-45 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_02960 7eee14080abdd3ca8c40c37996db36c7 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 255 2.9E-13 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_22155 e40ef881e83872edd38bc0b0735f34b0 50 Pfam PF08085 Entericidin EcnA/B family 29 49 2.6E-10 T 14-10-2018 IPR012556 Entericidin A/B GO:0009636|GO:0016020 TSH58p_31125 f0a9e1c515b0533086b3a190786b14da 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 312 6.2E-41 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_31125 f0a9e1c515b0533086b3a190786b14da 318 Gene3D G3DSA:1.10.3720.10 85 307 1.3E-20 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_31125 f0a9e1c515b0533086b3a190786b14da 318 SUPERFAMILY SSF161098 89 291 3.4E-19 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_02455 795fceb165dee0ffbd792d3de2611b16 175 SUPERFAMILY SSF55729 4 167 3.43E-15 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_02455 795fceb165dee0ffbd792d3de2611b16 175 Gene3D G3DSA:3.40.630.30 2 169 9.1E-13 T 14-10-2018 TSH58p_02455 795fceb165dee0ffbd792d3de2611b16 175 Pfam PF00583 Acetyltransferase (GNAT) family 88 141 3.7E-5 T 14-10-2018 IPR000182 GNAT domain TSH58p_08855 a43cf61d10c4a06acbde32d734c7976d 189 SUPERFAMILY SSF56235 1 169 3.0E-15 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_08855 a43cf61d10c4a06acbde32d734c7976d 189 Gene3D G3DSA:3.60.20.10 2 170 6.0E-14 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSH58p_24670 c18ac303050f905cd12ef3bbf44209be 262 Pfam PF07505 Protein of unknown function (DUF5131) 3 253 2.9E-97 T 14-10-2018 IPR011101 Protein of unknown function DUF5131 TSH58p_11785 9525b8ba42e353e8aebe54b72d1deb65 132 Pfam PF00072 Response regulator receiver domain 22 100 9.0E-5 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_11785 9525b8ba42e353e8aebe54b72d1deb65 132 SUPERFAMILY SSF52172 18 130 1.17E-13 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_11785 9525b8ba42e353e8aebe54b72d1deb65 132 Gene3D G3DSA:3.40.50.2300 15 132 4.2E-11 T 14-10-2018 TSH58p_01575 31b43e9389710ead13ffb709d6c9c4aa 283 Pfam PF00561 alpha/beta hydrolase fold 34 268 5.4E-24 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSH58p_01575 31b43e9389710ead13ffb709d6c9c4aa 283 Gene3D G3DSA:3.40.50.1820 16 281 8.4E-71 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_01575 31b43e9389710ead13ffb709d6c9c4aa 283 SUPERFAMILY SSF53474 10 281 4.2E-63 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_23975 2383d8d460a8a78cc312818b8b340359 156 Pfam PF01609 Transposase DDE domain 42 129 1.4E-7 T 14-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TSH58p_14740 0a5958da9983e2aba297d7ba7140cba9 374 Pfam PF12275 Protein of unknown function (DUF3616) 29 354 2.0E-124 T 14-10-2018 IPR022060 Protein of unknown function DUF3616 TSH58p_06535 82caf3fcb65041d4d9d1f01e724bc7a3 166 Gene3D G3DSA:2.60.40.420 46 166 4.2E-19 T 14-10-2018 IPR008972 Cupredoxin TSH58p_06535 82caf3fcb65041d4d9d1f01e724bc7a3 166 Pfam PF13473 Cupredoxin-like domain 54 165 5.8E-8 T 14-10-2018 IPR028096 EfeO-type cupredoxin-like domain TSH58p_06535 82caf3fcb65041d4d9d1f01e724bc7a3 166 SUPERFAMILY SSF49503 59 165 1.47E-17 T 14-10-2018 IPR008972 Cupredoxin TSH58p_29015 7f8012d67ac235ff2d1fd2592fb51f52 474 Pfam PF13454 FAD-NAD(P)-binding 11 166 1.1E-39 T 14-10-2018 IPR038732 FAD-dependent urate hydroxylase HpyO, FAD/NAD(P)-binding domain TSH58p_29015 7f8012d67ac235ff2d1fd2592fb51f52 474 SUPERFAMILY SSF51905 6 227 1.47E-16 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSH58p_00975 4e2234f46f5390353ed2cc02461bf09c 173 Gene3D G3DSA:2.60.40.1880 31 173 1.3E-30 T 14-10-2018 IPR038696 Invasion protein B superfamily TSH58p_00975 4e2234f46f5390353ed2cc02461bf09c 173 Pfam PF06776 Invasion associated locus B (IalB) protein 34 171 1.4E-28 T 14-10-2018 IPR010642 Invasion protein B TSH58p_27385 90859b4ba9a2f794bcf96111d1fbdc39 226 SMART SM00382 27 214 2.2E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain TSH58p_27385 90859b4ba9a2f794bcf96111d1fbdc39 226 SUPERFAMILY SSF52540 1 217 9.26E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_27385 90859b4ba9a2f794bcf96111d1fbdc39 226 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 214 3.2E-81 T 14-10-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 TSH58p_27385 90859b4ba9a2f794bcf96111d1fbdc39 226 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSH58p_27385 90859b4ba9a2f794bcf96111d1fbdc39 226 Gene3D G3DSA:3.40.50.300 1 223 1.2E-58 T 14-10-2018 TSH58p_27385 90859b4ba9a2f794bcf96111d1fbdc39 226 Pfam PF00005 ABC transporter 18 165 2.1E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSH58p_16020 81f412c940565d929d653b17437be168 453 Pfam PF11902 Protein of unknown function (DUF3422) 26 447 2.0E-171 T 14-10-2018 IPR021830 Protein of unknown function DUF3422 TSH58p_06015 b8bf9bd71782c01f5b91a84ddc8b82e2 241 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 28 237 1.4E-64 T 14-10-2018 IPR006214 Bax inhibitor 1-related TSH58p_05505 3cfdce0a2d20628a8662c404a1c40c24 176 SUPERFAMILY SSF52833 2 175 6.07E-36 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_05505 3cfdce0a2d20628a8662c404a1c40c24 176 Pfam PF08534 Redoxin 29 151 5.6E-28 T 14-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 TSH58p_05505 3cfdce0a2d20628a8662c404a1c40c24 176 Gene3D G3DSA:3.40.30.10 1 176 5.0E-61 T 14-10-2018 TSH58p_22905 66b04aaf794ad4dbcda6c215d676a4dc 692 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 13 184 1.6E-45 T 14-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 TSH58p_22905 66b04aaf794ad4dbcda6c215d676a4dc 692 Pfam PF01968 Hydantoinase/oxoprolinase 205 494 3.3E-90 T 14-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 TSH58p_20305 154b73186f07f87cd5bb6d2d3cb703d5 376 Pfam PF01594 AI-2E family transporter 27 349 2.9E-42 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like TSH58p_24565 6db4fb93a6a160e14d25ff86fc444da1 672 Pfam PF05170 AsmA family 7 168 2.3E-19 T 14-10-2018 IPR007844 AsmA TSH58p_24565 6db4fb93a6a160e14d25ff86fc444da1 672 Pfam PF05170 AsmA family 296 539 3.2E-21 T 14-10-2018 IPR007844 AsmA TSH58p_06845 abe07c62604bc2baf9ce7e89f8db764b 1170 Pfam PF05170 AsmA family 4 189 1.2E-27 T 14-10-2018 IPR007844 AsmA TSH58p_06845 abe07c62604bc2baf9ce7e89f8db764b 1170 Pfam PF13502 AsmA-like C-terminal region 908 1111 1.4E-26 T 14-10-2018 IPR032712 AsmA-like, C-terminal TSH58p_06845 abe07c62604bc2baf9ce7e89f8db764b 1170 Pfam PF13502 AsmA-like C-terminal region 420 646 1.0E-5 T 14-10-2018 IPR032712 AsmA-like, C-terminal TSH58p_10760 b81e62fa69981cb917f039a64817bad6 253 Pfam PF03692 Putative zinc- or iron-chelating domain 6 110 6.7E-8 T 14-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein TSH58p_04875 92e56fd63e531e5f0f1b8625141fe381 74 SUPERFAMILY SSF140376 4 73 7.06E-19 T 14-10-2018 IPR037205 ChaB superfamily TSH58p_04875 92e56fd63e531e5f0f1b8625141fe381 74 Gene3D G3DSA:1.10.1740.70 2 74 3.6E-23 T 14-10-2018 TSH58p_04875 92e56fd63e531e5f0f1b8625141fe381 74 Pfam PF06150 ChaB 9 73 1.8E-19 T 14-10-2018 IPR009317 ChaB TSH58p_17305 2fdedaad694fdba13b9f878db4e74e4a 202 Pfam PF02620 Uncharacterized ACR, COG1399 73 199 3.8E-14 T 14-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD TSH58p_29135 4c3b74a1810d87a720c857e36e4537d1 335 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 6 324 2.4E-96 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 TSH58p_29135 4c3b74a1810d87a720c857e36e4537d1 335 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 6 213 2.8E-44 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 TSH58p_04330 6377dbb4fcfb12af04198fe15c8f256e 317 SUPERFAMILY SSF103481 55 140 6.67E-11 T 14-10-2018 TSH58p_04330 6377dbb4fcfb12af04198fe15c8f256e 317 Pfam PF00892 EamA-like transporter family 145 274 1.0E-8 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_04330 6377dbb4fcfb12af04198fe15c8f256e 317 Pfam PF00892 EamA-like transporter family 2 136 2.3E-11 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_04330 6377dbb4fcfb12af04198fe15c8f256e 317 SUPERFAMILY SSF103481 185 279 1.83E-11 T 14-10-2018 TSH58p_23985 b93b8264f4849440de225f93470844ce 130 ProSitePatterns PS00934 Glyoxalase I signature 1. 8 29 - T 14-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 TSH58p_23985 b93b8264f4849440de225f93470844ce 130 Gene3D G3DSA:3.10.180.10 7 128 2.7E-41 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSH58p_23985 b93b8264f4849440de225f93470844ce 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 122 2.8E-9 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TSH58p_23985 b93b8264f4849440de225f93470844ce 130 SUPERFAMILY SSF54593 1 125 1.14E-28 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSH58p_26375 93886b71e5c08bfa4303a8b130c9e048 62 Gene3D G3DSA:3.30.429.10 1 61 1.0E-24 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily TSH58p_26375 93886b71e5c08bfa4303a8b130c9e048 62 SUPERFAMILY SSF55331 1 60 1.05E-19 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily TSH58p_26375 93886b71e5c08bfa4303a8b130c9e048 62 Pfam PF01361 Tautomerase enzyme 2 57 3.5E-18 T 14-10-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 TSH58p_03370 12e6ecdacf2d93130e7c72d72d87cdb7 177 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 20 167 8.9E-21 T 14-10-2018 IPR009936 Protein of unknown function DUF1468 TSH58p_17670 c23ab32c463f5f987ef366ef11efccd2 69 Gene3D G3DSA:1.10.260.40 1 65 1.8E-20 T 14-10-2018 TSH58p_17670 c23ab32c463f5f987ef366ef11efccd2 69 SUPERFAMILY SSF47413 2 56 4.15E-9 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_17670 c23ab32c463f5f987ef366ef11efccd2 69 Pfam PF13560 Helix-turn-helix domain 2 50 4.4E-8 T 14-10-2018 TSH58p_03510 c23ab32c463f5f987ef366ef11efccd2 69 Gene3D G3DSA:1.10.260.40 1 65 1.8E-20 T 14-10-2018 TSH58p_03510 c23ab32c463f5f987ef366ef11efccd2 69 SUPERFAMILY SSF47413 2 56 4.15E-9 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_03510 c23ab32c463f5f987ef366ef11efccd2 69 Pfam PF13560 Helix-turn-helix domain 2 50 4.4E-8 T 14-10-2018 TSH58p_09160 00d96647ef3a9404f9dab7ed631eaa46 106 Pfam PF13467 Ribbon-helix-helix domain 14 76 1.9E-24 T 14-10-2018 IPR027373 Ribbon-helix-helix domain TSH58p_09160 00d96647ef3a9404f9dab7ed631eaa46 106 Gene3D G3DSA:1.10.3990.20 10 98 1.0E-14 T 14-10-2018 IPR038268 Ribbon-helix-helix domain superfamily TSH58p_30430 b0d64c6293b0f01ac20cf3693daadedb 372 Gene3D G3DSA:3.40.50.2300 27 357 9.8E-73 T 14-10-2018 TSH58p_30430 b0d64c6293b0f01ac20cf3693daadedb 372 Gene3D G3DSA:3.40.50.2300 142 367 9.8E-73 T 14-10-2018 TSH58p_30430 b0d64c6293b0f01ac20cf3693daadedb 372 Pfam PF13458 Periplasmic binding protein 26 367 4.1E-62 T 14-10-2018 IPR028081 Leucine-binding protein domain TSH58p_30430 b0d64c6293b0f01ac20cf3693daadedb 372 SUPERFAMILY SSF53822 25 371 2.98E-74 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_12050 1fd00a3425c6076a7caefb66c954ead2 137 Pfam PF06803 Protein of unknown function (DUF1232) 68 103 5.3E-12 T 14-10-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 TSH58p_12050 1fd00a3425c6076a7caefb66c954ead2 137 PIRSF PIRSF031804 8 133 9.0E-40 T 14-10-2018 IPR016983 Uncharacterised conserved protein UCP031804 TSH58p_26480 f3828a573786660ded59444eadc2deaf 344 Gene3D G3DSA:3.60.10.10 7 334 1.5E-28 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TSH58p_26480 f3828a573786660ded59444eadc2deaf 344 SUPERFAMILY SSF56219 8 328 3.53E-28 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TSH58p_26480 f3828a573786660ded59444eadc2deaf 344 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 12 242 4.9E-9 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase TSH58p_31525 48d5591f00d00489d6cf3b8a63af3122 350 Pfam PF09084 NMT1/THI5 like 49 263 1.7E-41 T 14-10-2018 IPR015168 SsuA/THI5-like TSH58p_31525 48d5591f00d00489d6cf3b8a63af3122 350 Gene3D G3DSA:3.40.190.10 40 337 5.3E-61 T 14-10-2018 TSH58p_31525 48d5591f00d00489d6cf3b8a63af3122 350 Gene3D G3DSA:3.40.190.10 119 224 5.3E-61 T 14-10-2018 TSH58p_31525 48d5591f00d00489d6cf3b8a63af3122 350 SUPERFAMILY SSF53850 38 271 4.27E-34 T 14-10-2018 TSH58p_28035 f3b226ab7e042be7bad3d0d797627bba 389 Gene3D G3DSA:1.10.645.10 205 383 9.3E-30 T 14-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_28035 f3b226ab7e042be7bad3d0d797627bba 389 Pfam PF00374 Nickel-dependent hydrogenase 261 360 4.5E-10 T 14-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 TSH58p_28035 f3b226ab7e042be7bad3d0d797627bba 389 Gene3D G3DSA:1.10.645.10 5 136 2.3E-7 T 14-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_28035 f3b226ab7e042be7bad3d0d797627bba 389 SUPERFAMILY SSF56762 9 381 2.09E-45 T 14-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSH58p_03420 276d2213733e6edf6cfe8d83a11b5755 299 Pfam PF05876 Phage terminase large subunit (GpA) 37 245 1.6E-32 T 14-10-2018 IPR008866 Bacteriophage lambda, GpA TSH58p_03420 276d2213733e6edf6cfe8d83a11b5755 299 Gene3D G3DSA:3.40.50.300 18 188 1.3E-8 T 14-10-2018 TSH58p_14210 4454f70d58f4eec2656bc2d95ec50eb8 304 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 66 296 2.2E-49 T 14-10-2018 TSH58p_14210 4454f70d58f4eec2656bc2d95ec50eb8 304 PIRSF PIRSF000401 21 298 2.5E-50 T 14-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 TSH58p_14210 4454f70d58f4eec2656bc2d95ec50eb8 304 SUPERFAMILY SSF53335 52 293 1.63E-35 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_14210 4454f70d58f4eec2656bc2d95ec50eb8 304 Gene3D G3DSA:3.40.50.150 96 302 1.8E-43 T 14-10-2018 TSH58p_07245 817f2d0989351aa132b28a4bac1292df 189 Pfam PF05119 Phage terminase, small subunit 45 139 2.7E-20 T 14-10-2018 IPR006448 Putative phage terminase, small subunit, P27 family TSH58p_07245 817f2d0989351aa132b28a4bac1292df 189 TIGRFAM TIGR01558 sm_term_P27: putative phage terminase, small subunit, P27 family 37 138 1.4E-18 T 14-10-2018 IPR006448 Putative phage terminase, small subunit, P27 family TSH58p_20770 48dfa682cf7e6500a5bfe7cb88339b47 374 Gene3D G3DSA:2.130.10.10 41 347 2.6E-9 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TSH58p_20770 48dfa682cf7e6500a5bfe7cb88339b47 374 PIRSF PIRSF028101 1 373 3.5E-91 T 14-10-2018 IPR008311 Uncharacterised conserved protein UCP028101 TSH58p_20770 48dfa682cf7e6500a5bfe7cb88339b47 374 Pfam PF07433 Protein of unknown function (DUF1513) 68 371 1.2E-98 T 14-10-2018 IPR008311 Uncharacterised conserved protein UCP028101 TSH58p_20770 48dfa682cf7e6500a5bfe7cb88339b47 374 SUPERFAMILY SSF50969 60 343 2.79E-15 T 14-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like TSH58p_26145 cff78493658b161881f5fabee3c11eb4 103 SUPERFAMILY SSF54909 1 94 6.44E-20 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel TSH58p_13800 1ae63dc8dea8bb0c954971bf5b138bbe 304 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 293 3.1E-37 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_13825 d3f2fd4b31867af81ec171673386fd2a 563 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 94 221 3.0E-10 T 14-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like TSH58p_14235 1121da1de320e3e27c70a5db2378ef82 245 SUPERFAMILY SSF75708 71 245 1.57E-33 T 14-10-2018 TSH58p_14235 1121da1de320e3e27c70a5db2378ef82 245 Pfam PF04344 Chemotaxis phosphatase, CheZ 66 243 1.3E-10 T 14-10-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 TSH58p_14235 1121da1de320e3e27c70a5db2378ef82 245 Gene3D G3DSA:1.10.287.500 148 197 3.7E-5 T 14-10-2018 TSH58p_20585 a60bbec4501900eade9cd4e3e305239e 391 Pfam PF07958 Protein of unknown function (DUF1688) 1 391 2.6E-140 T 14-10-2018 IPR012469 Protein of unknown function DUF1688 TSH58p_03010 83b0c1343beae703b663d0fe3c6eea76 243 PIRSF PIRSF015736 1 243 1.6E-63 T 14-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase TSH58p_03010 83b0c1343beae703b663d0fe3c6eea76 243 Pfam PF01177 Asp/Glu/Hydantoin racemase 11 220 3.0E-9 T 14-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TSH58p_03010 83b0c1343beae703b663d0fe3c6eea76 243 Gene3D G3DSA:3.40.50.12500 2 240 1.1E-63 T 14-10-2018 TSH58p_31805 ae0ac96f0d3c9234a58b6a4d62e1c167 323 Gene3D G3DSA:3.40.190.10 42 299 1.6E-33 T 14-10-2018 TSH58p_31805 ae0ac96f0d3c9234a58b6a4d62e1c167 323 SUPERFAMILY SSF53850 35 264 7.25E-31 T 14-10-2018 TSH58p_31805 ae0ac96f0d3c9234a58b6a4d62e1c167 323 Pfam PF09084 NMT1/THI5 like 49 255 1.2E-25 T 14-10-2018 IPR015168 SsuA/THI5-like TSH58p_31805 ae0ac96f0d3c9234a58b6a4d62e1c167 323 Gene3D G3DSA:3.40.190.10 118 216 1.6E-33 T 14-10-2018 TSH58p_24110 daf779a0f06905fdafe51464fa1ef8a0 149 SUPERFAMILY SSF69118 4 145 2.44E-43 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TSH58p_24110 daf779a0f06905fdafe51464fa1ef8a0 149 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 30 76 4.5E-13 T 14-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TSH58p_24110 daf779a0f06905fdafe51464fa1ef8a0 149 Gene3D G3DSA:1.20.1290.10 1 148 2.8E-47 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TSH58p_24110 daf779a0f06905fdafe51464fa1ef8a0 149 Pfam PF02627 Carboxymuconolactone decarboxylase family 15 94 4.7E-18 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TSH58p_06715 96db55de83794d6f790967ddfa8a6698 221 SUPERFAMILY SSF52266 3 199 2.2E-6 T 14-10-2018 TSH58p_06715 96db55de83794d6f790967ddfa8a6698 221 Gene3D G3DSA:3.40.50.1110 2 217 8.4E-10 T 14-10-2018 IPR036514 SGNH hydrolase superfamily TSH58p_18115 f5f488faac539fc7cc2eb0649fc1a1e8 282 Gene3D G3DSA:3.40.1160.10 37 282 3.7E-56 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSH58p_18115 f5f488faac539fc7cc2eb0649fc1a1e8 282 PIRSF PIRSF039097 6 278 2.1E-96 T 14-10-2018 IPR030669 Molybdenum storage protein subunit alpha/beta GO:0005737|GO:0030151 TSH58p_18115 f5f488faac539fc7cc2eb0649fc1a1e8 282 SUPERFAMILY SSF53633 47 276 6.68E-27 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSH58p_18115 f5f488faac539fc7cc2eb0649fc1a1e8 282 Pfam PF00696 Amino acid kinase family 46 246 2.8E-19 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TSH58p_17440 9bb8414cf1c4de80c12f4e2f62c2b076 338 Pfam PF07505 Protein of unknown function (DUF5131) 4 334 4.7E-93 T 14-10-2018 IPR011101 Protein of unknown function DUF5131 TSH58p_08040 e8f5efefc8e233ddfe17037fbdfd4b53 161 Pfam PF09361 Phasin protein 47 144 1.3E-24 T 14-10-2018 IPR018968 Phasin TSH58p_08040 e8f5efefc8e233ddfe17037fbdfd4b53 161 TIGRFAM TIGR01841 phasin: phasin family protein 67 150 4.8E-12 T 14-10-2018 IPR010127 Phasin, subfamily 1 TSH58p_10995 baf8f03518b20d7129a202448e93f167 454 Pfam PF13449 Esterase-like activity of phytase 97 425 7.3E-63 T 14-10-2018 IPR027372 Phytase-like domain TSH58p_15040 3b9f97000e8b00450bfb27ca0d6b37d7 152 SUPERFAMILY SSF47188 13 120 4.58E-12 T 14-10-2018 IPR035938 Hemerythrin-like superfamily TSH58p_15040 3b9f97000e8b00450bfb27ca0d6b37d7 152 Gene3D G3DSA:1.20.120.50 9 127 1.1E-8 T 14-10-2018 IPR035938 Hemerythrin-like superfamily TSH58p_13290 4b50c21c4efe2b5373291a107b92dd58 279 SUPERFAMILY SSF52402 155 278 8.37E-22 T 14-10-2018 TSH58p_13290 4b50c21c4efe2b5373291a107b92dd58 279 Gene3D G3DSA:3.40.50.12370 5 278 3.1E-34 T 14-10-2018 TSH58p_13290 4b50c21c4efe2b5373291a107b92dd58 279 Pfam PF00582 Universal stress protein family 155 277 1.8E-12 T 14-10-2018 IPR006016 UspA TSH58p_13290 4b50c21c4efe2b5373291a107b92dd58 279 Pfam PF00582 Universal stress protein family 5 118 2.0E-5 T 14-10-2018 IPR006016 UspA TSH58p_13290 4b50c21c4efe2b5373291a107b92dd58 279 SUPERFAMILY SSF52402 2 145 1.42E-12 T 14-10-2018 TSH58p_13290 4b50c21c4efe2b5373291a107b92dd58 279 PRINTS PR01438 Universal stress protein signature 239 251 2.7E-8 T 14-10-2018 IPR006015 Universal stress protein A TSH58p_13290 4b50c21c4efe2b5373291a107b92dd58 279 PRINTS PR01438 Universal stress protein signature 154 172 2.7E-8 T 14-10-2018 IPR006015 Universal stress protein A TSH58p_13290 4b50c21c4efe2b5373291a107b92dd58 279 PRINTS PR01438 Universal stress protein signature 257 279 2.7E-8 T 14-10-2018 IPR006015 Universal stress protein A TSH58p_11575 99fcf39ac910974b9645e83d389921b1 121 Pfam PF11162 Protein of unknown function (DUF2946) 3 118 7.6E-7 T 14-10-2018 IPR021333 Protein of unknown function DUF2946 TSH58p_18255 e26eb9d4b3978db7e7918c334b57a486 550 SUPERFAMILY SSF53448 1 245 1.32E-14 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_07140 e93d00003e7b5cb4ed94b8d313fd19df 132 Pfam PF11351 Holin of 3TMs, for gene-transfer release 15 118 6.4E-14 T 14-10-2018 IPR021497 Holin of 3TMs, for gene-transfer release TSH58p_10335 144cf7fed5169fc26daa1a70434595d7 361 Hamap MF_01665 Heme A synthase [ctaA]. 20 356 24.476 T 14-10-2018 IPR023754 Heme A synthase, type 2 GO:0006784|GO:0016020|GO:0016627|GO:0055114 Reactome: R-HSA-189451 TSH58p_10335 144cf7fed5169fc26daa1a70434595d7 361 Pfam PF02628 Cytochrome oxidase assembly protein 24 344 4.0E-105 T 14-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 TSH58p_25550 e7914ccfc999a01568c0232fd9dd9944 363 Gene3D G3DSA:1.10.3720.10 150 353 1.9E-21 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_25550 e7914ccfc999a01568c0232fd9dd9944 363 SUPERFAMILY SSF161098 150 348 3.27E-23 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_25550 e7914ccfc999a01568c0232fd9dd9944 363 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 174 355 1.8E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_22650 07d6451557858d3b5db9f27405a8cf2f 1299 Pfam PF06791 Prophage tail length tape measure protein 104 239 1.1E-8 T 14-10-2018 IPR009628 Bacteriophage lambda, GpH, tail tape measure, N-terminal TSH58p_14945 6570abf41a4eeac2f4c9c19eeaaa3577 379 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 40 355 8.7E-135 T 14-10-2018 IPR017778 ABC transporter, urea, permease protein, UrtC TSH58p_14945 6570abf41a4eeac2f4c9c19eeaaa3577 379 Pfam PF02653 Branched-chain amino acid transport system / permease component 50 344 1.8E-39 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_12945 460844d84d3d333be7989704d559af75 106 Pfam PF01809 Haemolytic domain 7 71 2.0E-27 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor TSH58p_12945 460844d84d3d333be7989704d559af75 106 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 19 71 1.0E-16 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor TSH58p_12945 460844d84d3d333be7989704d559af75 106 SMART SM01234 4 71 3.6E-37 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor TSH58p_12945 460844d84d3d333be7989704d559af75 106 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 4 72 22.986 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor TSH58p_12945 460844d84d3d333be7989704d559af75 106 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 10 76 2.3E-26 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor TSH58p_01660 61558a9ddd34f4223bc01f888e5376ca 342 Gene3D G3DSA:1.10.3470.10 3 341 8.3E-100 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_01660 61558a9ddd34f4223bc01f888e5376ca 342 Pfam PF01032 FecCD transport family 17 338 2.5E-93 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TSH58p_01660 61558a9ddd34f4223bc01f888e5376ca 342 SUPERFAMILY SSF81345 4 339 3.4E-81 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_06975 a098291cf81f6d5bb23a80d396f8495e 360 Pfam PF00534 Glycosyl transferases group 1 178 321 2.5E-20 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 TSH58p_06975 a098291cf81f6d5bb23a80d396f8495e 360 Gene3D G3DSA:3.40.50.2000 19 347 1.4E-51 T 14-10-2018 TSH58p_06975 a098291cf81f6d5bb23a80d396f8495e 360 SUPERFAMILY SSF53756 25 350 5.1E-44 T 14-10-2018 TSH58p_06975 a098291cf81f6d5bb23a80d396f8495e 360 Gene3D G3DSA:3.40.50.2000 166 342 1.4E-51 T 14-10-2018 TSH58p_11260 d7314b1093f8db6bd605479a2e259215 230 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 6 203 3.0E-25 T 14-10-2018 TSH58p_10385 27ab054e212fbcb633e8feb40078c935 231 Gene3D G3DSA:3.40.50.1110 45 227 4.1E-70 T 14-10-2018 IPR036514 SGNH hydrolase superfamily TSH58p_10385 27ab054e212fbcb633e8feb40078c935 231 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 49 207 1.7E-27 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain TSH58p_10385 27ab054e212fbcb633e8feb40078c935 231 SUPERFAMILY SSF52266 42 223 3.97E-50 T 14-10-2018 TSH58p_10320 9e312a156062d389c76d13e2bd80a021 87 Pfam PF06233 Usg-like family 7 85 1.2E-39 T 14-10-2018 IPR009354 Usg-like TSH58p_08370 495d9f725f3984bfe3dfc5d41d66322c 365 Pfam PF01594 AI-2E family transporter 22 353 1.5E-45 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like TSH58p_20690 49dd5829c4c9aca56d1c566435b8aba5 199 Pfam PF07811 TadE-like protein 17 55 8.7E-9 T 14-10-2018 IPR012495 TadE-like TSH58p_04635 2a2a7f11642b18827b2aae260b7a0e70 136 Gene3D G3DSA:1.10.10.1550 57 112 2.6E-29 T 14-10-2018 TSH58p_04635 2a2a7f11642b18827b2aae260b7a0e70 136 Pfam PF05443 ROS/MUCR transcriptional regulator protein 9 129 7.5E-48 T 14-10-2018 IPR008807 ROSMUCR transcriptional regulator GO:0003677|GO:0006355|GO:0008270 TSH58p_17420 0c35e4e508016073cf3c577047876ccd 232 Pfam PF11672 zinc-finger-containing domain 12 86 1.0E-8 T 14-10-2018 IPR021686 Protein of unkown function DUF3268 TSH58p_21180 5d253d3fd563691a3ca2b3e0e29281eb 330 SUPERFAMILY SSF53822 43 269 1.57E-8 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_21180 5d253d3fd563691a3ca2b3e0e29281eb 330 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 38 328 1.6E-42 T 14-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 TSH58p_21180 5d253d3fd563691a3ca2b3e0e29281eb 330 Gene3D G3DSA:3.40.50.2300 33 288 7.0E-82 T 14-10-2018 TSH58p_21180 5d253d3fd563691a3ca2b3e0e29281eb 330 Gene3D G3DSA:3.40.50.2300 132 324 7.0E-82 T 14-10-2018 TSH58p_23155 b40bf88b548342fa3f8c0e132ed6a6ee 330 Pfam PF14390 Putative PD-(D/E)XK family member, (DUF4420) 10 306 1.9E-65 T 14-10-2018 IPR025534 Putative PD-(D/E)XK family member (DUF4420) TSH58p_28330 956dc13b83b8b367a03674fa5bd4163f 239 Pfam PF06055 Exopolysaccharide synthesis, ExoD 33 209 2.4E-49 T 14-10-2018 IPR010331 Exopolysaccharide synthesis, ExoD TSH58p_28330 956dc13b83b8b367a03674fa5bd4163f 239 PIRSF PIRSF033239 21 224 1.7E-46 T 14-10-2018 IPR010331 Exopolysaccharide synthesis, ExoD TSH58p_09545 f8e5d65725fd91ef056b5d4af8a142a6 364 Gene3D G3DSA:2.40.128.140 61 362 7.3E-82 T 14-10-2018 IPR037107 Putative outer membrane protein superfamily TSH58p_09545 f8e5d65725fd91ef056b5d4af8a142a6 364 Pfam PF09982 Uncharacterized protein conserved in bacteria (DUF2219) 63 363 1.5E-95 T 14-10-2018 IPR018707 Protein of unknown function DUF2219 TSH58p_03185 8e681cf14b9010684ecd0c500a34992c 337 Pfam PF02653 Branched-chain amino acid transport system / permease component 38 298 7.1E-41 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_21285 3fd5dc54d1637fc35c6dcfb429dc798f 166 PRINTS PR00050 Cold shock protein signature 139 157 3.5E-8 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_21285 3fd5dc54d1637fc35c6dcfb429dc798f 166 PRINTS PR00050 Cold shock protein signature 103 118 3.5E-8 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_21285 3fd5dc54d1637fc35c6dcfb429dc798f 166 PRINTS PR00050 Cold shock protein signature 124 133 3.5E-8 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_21285 3fd5dc54d1637fc35c6dcfb429dc798f 166 SUPERFAMILY SSF50249 101 165 2.57E-16 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_21285 3fd5dc54d1637fc35c6dcfb429dc798f 166 SUPERFAMILY SSF50249 15 75 3.21E-13 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSH58p_21285 3fd5dc54d1637fc35c6dcfb429dc798f 166 SMART SM00357 102 166 6.8E-14 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 TSH58p_21285 3fd5dc54d1637fc35c6dcfb429dc798f 166 SMART SM00357 13 77 5.4E-7 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 TSH58p_21285 3fd5dc54d1637fc35c6dcfb429dc798f 166 Gene3D G3DSA:2.40.50.140 11 75 6.6E-14 T 14-10-2018 TSH58p_21285 3fd5dc54d1637fc35c6dcfb429dc798f 166 Gene3D G3DSA:2.40.50.140 99 164 2.2E-18 T 14-10-2018 TSH58p_21285 3fd5dc54d1637fc35c6dcfb429dc798f 166 Pfam PF00313 'Cold-shock' DNA-binding domain 102 164 1.8E-16 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_21285 3fd5dc54d1637fc35c6dcfb429dc798f 166 Pfam PF00313 'Cold-shock' DNA-binding domain 15 74 2.1E-11 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSH58p_04220 3f0d9ba387dfc2048b70f6caf357f6fb 701 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 414 615 5.8E-30 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TSH58p_04220 3f0d9ba387dfc2048b70f6caf357f6fb 701 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 130 396 3.7E-57 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TSH58p_04220 3f0d9ba387dfc2048b70f6caf357f6fb 701 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 33 690 6.7E-222 T 14-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ TSH58p_24070 78e0adb1b778f0b4d297345554d5855f 136 Pfam PF01890 Cobalamin synthesis G C-terminus 7 129 5.8E-25 T 14-10-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 TSH58p_24070 78e0adb1b778f0b4d297345554d5855f 136 SUPERFAMILY SSF159664 4 131 4.32E-28 T 14-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 TSH58p_24070 78e0adb1b778f0b4d297345554d5855f 136 Gene3D G3DSA:3.30.420.180 1 133 9.0E-35 T 14-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 TSH58p_12325 d45b0e924e9b56f4b024238d1a6f6934 211 SUPERFAMILY SSF55083 17 142 2.09E-17 T 14-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TSH58p_12325 d45b0e924e9b56f4b024238d1a6f6934 211 Gene3D G3DSA:3.30.70.560 15 149 5.1E-14 T 14-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TSH58p_12325 d45b0e924e9b56f4b024238d1a6f6934 211 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 18 140 2.0E-10 T 14-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TSH58p_26795 278b0dd7eaf0365afe315d6f42d50f98 497 SUPERFAMILY SSF56317 232 456 7.46E-19 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TSH58p_26795 278b0dd7eaf0365afe315d6f42d50f98 497 Gene3D G3DSA:3.60.110.10 227 475 3.9E-14 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TSH58p_24405 f451e5196b5fa2c50d065f52ac259ce3 338 SUPERFAMILY SSF63829 22 319 6.54E-22 T 14-10-2018 TSH58p_24405 f451e5196b5fa2c50d065f52ac259ce3 338 Gene3D G3DSA:2.120.10.30 4 320 8.1E-43 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TSH58p_03815 169a03a8f5989656696567568442d03e 348 Pfam PF13379 NMT1-like family 35 278 5.5E-29 T 14-10-2018 TSH58p_03815 169a03a8f5989656696567568442d03e 348 Gene3D G3DSA:3.40.190.10 34 146 1.9E-20 T 14-10-2018 TSH58p_03815 169a03a8f5989656696567568442d03e 348 SUPERFAMILY SSF53850 36 275 4.71E-31 T 14-10-2018 TSH58p_03815 169a03a8f5989656696567568442d03e 348 Gene3D G3DSA:3.40.190.10 147 348 1.4E-22 T 14-10-2018 TSH58p_24485 190487229de6facb521fc7569179341b 247 Pfam PF01925 Sulfite exporter TauE/SafE 9 242 2.4E-31 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TSH58p_08075 1a2741a9323b2f61094abee0e1e6c255 402 Pfam PF04339 Peptidogalycan biosysnthesis/recognition 29 395 6.1E-155 T 14-10-2018 IPR007434 Peptidogalycan biosysnthesis/recognition TSH58p_08075 1a2741a9323b2f61094abee0e1e6c255 402 Gene3D G3DSA:3.40.630.30 196 344 2.4E-5 T 14-10-2018 TSH58p_08075 1a2741a9323b2f61094abee0e1e6c255 402 SUPERFAMILY SSF55729 198 372 5.6E-38 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_27185 dc6ad2f32a75d150ce91d774f0819e89 255 Pfam PF07812 TfuA-like protein 52 170 4.2E-49 T 14-10-2018 IPR012924 TfuA-like, core TSH58p_22265 f76b3250fefa7a117375913847c5941a 225 Pfam PF04191 Phospholipid methyltransferase 102 194 3.9E-8 T 14-10-2018 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 TSH58p_22265 f76b3250fefa7a117375913847c5941a 225 Gene3D G3DSA:1.20.120.1630 7 209 2.3E-20 T 14-10-2018 TSH58p_18295 019cb668c6db4d65382fe644a71a2fce 472 Gene3D G3DSA:3.40.50.150 87 260 1.2E-12 T 14-10-2018 TSH58p_18295 019cb668c6db4d65382fe644a71a2fce 472 SUPERFAMILY SSF53335 101 246 5.27E-9 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_16665 bdecc7e4e3ec04a4590f4858a2bee016 265 Pfam PF04305 Protein of unknown function (DUF455) 15 261 1.6E-105 T 14-10-2018 IPR007402 Protein of unknown function DUF455 TSH58p_16665 bdecc7e4e3ec04a4590f4858a2bee016 265 PIRSF PIRSF012318 1 265 6.3E-97 T 14-10-2018 IPR011197 Uncharacterised conserved protein UCP012318 TSH58p_16665 bdecc7e4e3ec04a4590f4858a2bee016 265 SUPERFAMILY SSF47240 72 218 1.85E-21 T 14-10-2018 IPR009078 Ferritin-like superfamily TSH58p_02645 46e8231fd0eae39290bd2254c1d309ce 77 TIGRFAM TIGR02973 nitrate_rd_NapE: periplasmic nitrate reductase, NapE protein 32 73 1.1E-22 T 14-10-2018 IPR004448 Nitrate reductas, NapE, periplasmic TSH58p_02645 46e8231fd0eae39290bd2254c1d309ce 77 Pfam PF06796 Periplasmic nitrate reductase protein NapE 28 74 8.9E-24 T 14-10-2018 IPR010649 Nitrate/trimethylamine N-oxide reductase NapE/TorE TSH58p_17270 b6b79a34eb15c623ab906011b4b8c395 154 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 1 149 23.346 T 14-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TSH58p_17270 b6b79a34eb15c623ab906011b4b8c395 154 Gene3D G3DSA:3.40.50.960 1 151 1.5E-49 T 14-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TSH58p_17270 b6b79a34eb15c623ab906011b4b8c395 154 SUPERFAMILY SSF52121 3 149 5.76E-47 T 14-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TSH58p_17270 b6b79a34eb15c623ab906011b4b8c395 154 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 8 144 7.4E-30 T 14-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TSH58p_17270 b6b79a34eb15c623ab906011b4b8c395 154 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 6 146 4.9E-43 T 14-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TSH58p_30450 b9a727f2bae669ef5ee00619fab72717 297 Pfam PF02653 Branched-chain amino acid transport system / permease component 6 277 8.5E-39 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_02765 fdb11f5c78301dd96f0b402ebd2aa5c3 326 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 323 8.0E-44 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_02765 fdb11f5c78301dd96f0b402ebd2aa5c3 326 SUPERFAMILY SSF161098 95 310 6.41E-22 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_02765 fdb11f5c78301dd96f0b402ebd2aa5c3 326 Gene3D G3DSA:1.10.3720.10 90 318 4.3E-26 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_22750 12524365e6124e4e66384f2e6b471907 936 SMART SM00493 209 281 0.0034 T 14-10-2018 IPR006171 TOPRIM domain TSH58p_22750 12524365e6124e4e66384f2e6b471907 936 Gene3D G3DSA:3.40.1360.10 196 318 5.1E-6 T 14-10-2018 TSH58p_23005 01731ea79a86c6e24506a35314e05297 536 Gene3D G3DSA:3.40.50.410 329 520 2.8E-16 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TSH58p_23005 01731ea79a86c6e24506a35314e05297 536 SUPERFAMILY SSF53300 336 530 1.06E-18 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TSH58p_23005 01731ea79a86c6e24506a35314e05297 536 SMART SM00327 335 535 3.3E-15 T 14-10-2018 IPR002035 von Willebrand factor, type A TSH58p_30400 b97463298257866967efefdf9753698b 205 Pfam PF05995 Cysteine dioxygenase type I 58 161 6.0E-6 T 14-10-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 TSH58p_30400 b97463298257866967efefdf9753698b 205 SUPERFAMILY SSF51182 10 198 1.94E-55 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_30400 b97463298257866967efefdf9753698b 205 Gene3D G3DSA:2.60.120.10 49 190 2.3E-54 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_30400 b97463298257866967efefdf9753698b 205 Gene3D G3DSA:1.20.5.440 3 48 2.8E-7 T 14-10-2018 TSH58p_10725 238ce45533d09aff333b48735b68285e 310 Pfam PF04796 Plasmid encoded RepA protein 93 246 4.6E-49 T 14-10-2018 IPR006881 Plasmid encoded RepA protein TSH58p_30085 b2ad88d09ae9d745ec9ccbdc408bfa6a 275 Pfam PF12787 EcsC protein family 25 246 1.7E-41 T 14-10-2018 IPR024787 EcsC protein TSH58p_07980 96db26d5f8d95bff32ed8c3426b81a96 66 PIRSF PIRSF036704 1 65 1.5E-10 T 14-10-2018 IPR014177 Putative formate dehydrogenase, TAT signal-containing TSH58p_23040 75e81425034e7b8002294f6a4404eed9 293 SUPERFAMILY SSF161098 85 272 1.83E-27 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_23040 75e81425034e7b8002294f6a4404eed9 293 Gene3D G3DSA:1.10.3720.10 82 287 6.9E-24 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_23040 75e81425034e7b8002294f6a4404eed9 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 288 3.0E-30 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_06050 dca9c381d8b62db8da426d821b53e6f8 152 Pfam PF01814 Hemerythrin HHE cation binding domain 4 116 5.6E-12 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 TSH58p_06050 dca9c381d8b62db8da426d821b53e6f8 152 Gene3D G3DSA:1.20.120.520 1 140 1.6E-10 T 14-10-2018 TSH58p_21890 c8576afd906161fb63a7056e8699d8ae 138 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 20 133 8.7E-33 T 14-10-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III TSH58p_15565 8440d017112834a9217cb6cefcba3ef0 183 Pfam PF13328 HD domain 10 137 1.3E-23 T 14-10-2018 IPR003607 HD/PDEase domain TSH58p_15565 8440d017112834a9217cb6cefcba3ef0 183 Gene3D G3DSA:1.10.3210.10 3 175 4.9E-56 T 14-10-2018 TSH58p_15565 8440d017112834a9217cb6cefcba3ef0 183 SMART SM00471 27 135 2.4E-10 T 14-10-2018 IPR003607 HD/PDEase domain TSH58p_15565 8440d017112834a9217cb6cefcba3ef0 183 SUPERFAMILY SSF109604 7 171 6.57E-44 T 14-10-2018 TSH58p_27340 fc1bff9ef870674f34b75073310133ef 260 Gene3D G3DSA:3.40.50.360 1 259 1.0E-100 T 14-10-2018 IPR029039 Flavoprotein-like superfamily TSH58p_27340 fc1bff9ef870674f34b75073310133ef 260 Pfam PF02525 Flavodoxin-like fold 1 215 4.4E-58 T 14-10-2018 IPR003680 Flavodoxin-like fold TSH58p_27340 fc1bff9ef870674f34b75073310133ef 260 SUPERFAMILY SSF52218 1 242 1.36E-73 T 14-10-2018 IPR029039 Flavoprotein-like superfamily TSH58p_09275 ef1c597e5bc15e2d42f55c8c89c50bff 501 Pfam PF12236 Bacteriophage head to tail connecting protein 30 496 7.5E-163 T 14-10-2018 IPR020991 Head-to-tail connector protein, podovirus-type TSH58p_07625 36ba8ff5a65ddf807d08f408dff0a8b4 295 Pfam PF07357 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) 31 291 2.9E-102 T 14-10-2018 IPR009953 Dinitrogenase reductase ADP-ribosyltransferase GO:0009399|GO:0030701 TSH58p_19135 f397c6e297a798937a3abcab2188b477 378 Pfam PF02119 Flagellar P-ring protein 35 377 1.1E-136 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 TSH58p_19135 f397c6e297a798937a3abcab2188b477 378 PRINTS PR01010 Flagellar P-ring protein signature 134 152 8.0E-80 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 TSH58p_19135 f397c6e297a798937a3abcab2188b477 378 PRINTS PR01010 Flagellar P-ring protein signature 200 218 8.0E-80 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 TSH58p_19135 f397c6e297a798937a3abcab2188b477 378 PRINTS PR01010 Flagellar P-ring protein signature 174 192 8.0E-80 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 TSH58p_19135 f397c6e297a798937a3abcab2188b477 378 PRINTS PR01010 Flagellar P-ring protein signature 70 85 8.0E-80 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 TSH58p_19135 f397c6e297a798937a3abcab2188b477 378 PRINTS PR01010 Flagellar P-ring protein signature 117 134 8.0E-80 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 TSH58p_19135 f397c6e297a798937a3abcab2188b477 378 PRINTS PR01010 Flagellar P-ring protein signature 35 50 8.0E-80 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 TSH58p_19135 f397c6e297a798937a3abcab2188b477 378 PRINTS PR01010 Flagellar P-ring protein signature 50 65 8.0E-80 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 TSH58p_19135 f397c6e297a798937a3abcab2188b477 378 PRINTS PR01010 Flagellar P-ring protein signature 264 276 8.0E-80 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 TSH58p_19135 f397c6e297a798937a3abcab2188b477 378 PRINTS PR01010 Flagellar P-ring protein signature 95 114 8.0E-80 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 TSH58p_19135 f397c6e297a798937a3abcab2188b477 378 Hamap MF_00416 Flagellar P-ring protein [flgI]. 15 378 35.968 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 TSH58p_03695 a34f4105142ff219641483292a78a4ad 82 SUPERFAMILY SSF47413 7 44 9.86E-6 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSH58p_03695 a34f4105142ff219641483292a78a4ad 82 Pfam PF01381 Helix-turn-helix 9 39 1.8E-5 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSH58p_03695 a34f4105142ff219641483292a78a4ad 82 Gene3D G3DSA:1.10.260.40 1 76 1.1E-16 T 14-10-2018 TSH58p_30390 260e7c205e9c94763450156aace7cb78 311 Gene3D G3DSA:3.40.250.10 169 302 1.2E-36 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily TSH58p_30390 260e7c205e9c94763450156aace7cb78 311 Gene3D G3DSA:3.40.250.10 19 167 3.5E-43 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily TSH58p_30390 260e7c205e9c94763450156aace7cb78 311 SUPERFAMILY SSF52821 27 163 1.44E-35 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily TSH58p_30390 260e7c205e9c94763450156aace7cb78 311 ProSitePatterns PS00380 Rhodanese signature 1. 59 70 - T 14-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 TSH58p_30390 260e7c205e9c94763450156aace7cb78 311 SMART SM00450 172 298 1.3E-23 T 14-10-2018 IPR001763 Rhodanese-like domain TSH58p_30390 260e7c205e9c94763450156aace7cb78 311 SMART SM00450 33 147 3.6E-17 T 14-10-2018 IPR001763 Rhodanese-like domain TSH58p_30390 260e7c205e9c94763450156aace7cb78 311 ProSitePatterns PS00683 Rhodanese C-terminal signature. 282 292 - T 14-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 TSH58p_30390 260e7c205e9c94763450156aace7cb78 311 SUPERFAMILY SSF52821 174 301 1.7E-33 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily TSH58p_30390 260e7c205e9c94763450156aace7cb78 311 Pfam PF00581 Rhodanese-like domain 182 294 1.2E-17 T 14-10-2018 IPR001763 Rhodanese-like domain TSH58p_30390 260e7c205e9c94763450156aace7cb78 311 Pfam PF00581 Rhodanese-like domain 34 143 4.5E-19 T 14-10-2018 IPR001763 Rhodanese-like domain TSH58p_27530 0317e913e5c664f9ec80352219389448 65 Pfam PF06568 Domain of unknown function (DUF1127) 28 55 4.3E-10 T 14-10-2018 IPR009506 Protein of unknown function DUF1127 TSH58p_12065 714589e4c5ac3053bfd96704eb77b515 162 Pfam PF03918 Cytochrome C biogenesis protein 12 157 3.7E-52 T 14-10-2018 IPR005616 CcmH/CycL/Ccl2/NrfF family TSH58p_12065 714589e4c5ac3053bfd96704eb77b515 162 Gene3D G3DSA:1.10.8.640 20 103 9.4E-30 T 14-10-2018 IPR038297 CcmH/CycL/Ccl2/NrfF domain superfamily TSH58p_10265 25c782b948b0db10c5318781d1fef69b 223 Pfam PF04012 PspA/IM30 family 2 216 2.3E-37 T 14-10-2018 IPR007157 PspA/IM30 TSH58p_10265 25c782b948b0db10c5318781d1fef69b 223 TIGRFAM TIGR02977 phageshock_pspA: phage shock protein A 1 218 8.0E-84 T 14-10-2018 IPR014319 Phage shock protein, PspA TSH58p_30975 143a89a8720579fd60c37ff40b5e21da 274 SUPERFAMILY SSF161098 66 249 4.58E-19 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_30975 143a89a8720579fd60c37ff40b5e21da 274 Gene3D G3DSA:1.10.3720.10 66 255 8.9E-13 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_30975 143a89a8720579fd60c37ff40b5e21da 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 247 3.8E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_09755 c5d9d767d47c8fc6c06886f85fa38f15 272 Pfam PF01863 Protein of unknown function DUF45 41 238 1.4E-49 T 14-10-2018 IPR002725 Protein of unknown function DUF45 TSH58p_09755 c5d9d767d47c8fc6c06886f85fa38f15 272 Gene3D G3DSA:3.30.2010.10 150 236 1.9E-14 T 14-10-2018 TSH58p_31410 5072330189c0146c7f7c501bea97773f 138 Gene3D G3DSA:2.40.100.20 3 138 1.8E-39 T 14-10-2018 TSH58p_31410 5072330189c0146c7f7c501bea97773f 138 Pfam PF12903 Protein of unknown function (DUF3830) 5 137 7.5E-33 T 14-10-2018 IPR024532 Protein of unknown function DUF3830 TSH58p_08335 9c730c35a9e5a7859977fd99fdf250b2 411 Gene3D G3DSA:3.20.20.140 58 362 2.2E-128 T 14-10-2018 TSH58p_08335 9c730c35a9e5a7859977fd99fdf250b2 411 Pfam PF07969 Amidohydrolase family 111 380 5.4E-19 T 14-10-2018 IPR013108 Amidohydrolase 3 TSH58p_08335 9c730c35a9e5a7859977fd99fdf250b2 411 Gene3D G3DSA:2.30.40.10 21 399 2.2E-128 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_08335 9c730c35a9e5a7859977fd99fdf250b2 411 SUPERFAMILY SSF51556 57 372 4.98E-81 T 14-10-2018 IPR032466 Metal-dependent hydrolase TSH58p_08335 9c730c35a9e5a7859977fd99fdf250b2 411 SUPERFAMILY SSF51338 3 397 7.07E-19 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSH58p_03160 38073ccb015bbc0b1caa98c8bb7a8ed5 196 Pfam PF03358 NADPH-dependent FMN reductase 9 158 2.3E-33 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 TSH58p_03160 38073ccb015bbc0b1caa98c8bb7a8ed5 196 Gene3D G3DSA:3.40.50.360 1 196 1.2E-45 T 14-10-2018 IPR029039 Flavoprotein-like superfamily TSH58p_03160 38073ccb015bbc0b1caa98c8bb7a8ed5 196 SUPERFAMILY SSF52218 9 183 2.01E-40 T 14-10-2018 IPR029039 Flavoprotein-like superfamily TSH58p_12085 632283737c5b60b617f4d05359363796 72 Pfam PF04995 Heme exporter protein D (CcmD) 8 47 5.6E-13 T 14-10-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 TSH58p_12085 632283737c5b60b617f4d05359363796 72 TIGRFAM TIGR03141 cytochro_ccmD: heme exporter protein CcmD 5 47 1.5E-13 T 14-10-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 TSH58p_31790 8314dab091e194b71f330286248c690a 290 Gene3D G3DSA:3.20.20.60 1 289 2.5E-100 T 14-10-2018 TSH58p_31790 8314dab091e194b71f330286248c690a 290 Pfam PF13714 Phosphoenolpyruvate phosphomutase 9 254 6.7E-48 T 14-10-2018 TSH58p_31790 8314dab091e194b71f330286248c690a 290 SUPERFAMILY SSF51621 4 286 1.18E-85 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSH58p_14795 75584195cec9a5f40b50c1b68e8e444b 251 Gene3D G3DSA:3.40.30.10 77 251 4.6E-53 T 14-10-2018 TSH58p_14795 75584195cec9a5f40b50c1b68e8e444b 251 Pfam PF01323 DSBA-like thioredoxin domain 102 245 3.4E-28 T 14-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 TSH58p_14795 75584195cec9a5f40b50c1b68e8e444b 251 SUPERFAMILY SSF52833 79 245 6.43E-49 T 14-10-2018 IPR036249 Thioredoxin-like superfamily TSH58p_32000 ff22a794d87991f0d6d7ebd3521f8710 255 Pfam PF13610 DDE domain 72 211 1.8E-51 T 14-10-2018 IPR032874 DDE domain TSH58p_32000 ff22a794d87991f0d6d7ebd3521f8710 255 SUPERFAMILY SSF53098 73 190 7.08E-6 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily TSH58p_29330 d5c0c2c24ed20ab402831102a7496ab2 265 Pfam PF08241 Methyltransferase domain 62 156 6.3E-10 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TSH58p_29330 d5c0c2c24ed20ab402831102a7496ab2 265 Gene3D G3DSA:3.40.50.150 30 243 1.0E-22 T 14-10-2018 TSH58p_29330 d5c0c2c24ed20ab402831102a7496ab2 265 SUPERFAMILY SSF53335 24 235 3.75E-24 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_29915 fab00ea2fd6e93c4084da1837b10baf0 271 Pfam PF01578 Cytochrome C assembly protein 69 269 2.9E-15 T 14-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 TSH58p_31705 645307e3937e47e9c5214c43367eb9a1 248 SMART SM00849 17 198 1.7E-7 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_31705 645307e3937e47e9c5214c43367eb9a1 248 Gene3D G3DSA:3.60.15.10 1 243 4.1E-40 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_31705 645307e3937e47e9c5214c43367eb9a1 248 Pfam PF12706 Beta-lactamase superfamily domain 29 217 4.7E-17 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_31705 645307e3937e47e9c5214c43367eb9a1 248 SUPERFAMILY SSF56281 1 219 3.93E-39 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_23355 296359fa378a544ba27b18ad8e7aaf8b 178 TIGRFAM TIGR03358 VI_chp_5: type VI secretion protein, VC_A0107 family 6 160 5.7E-55 T 14-10-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 TSH58p_23355 296359fa378a544ba27b18ad8e7aaf8b 178 PIRSF PIRSF028301 1 172 1.2E-59 T 14-10-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 TSH58p_23355 296359fa378a544ba27b18ad8e7aaf8b 178 Pfam PF05591 Type VI secretion system, VipA, VC_A0107 or Hcp2 10 161 1.5E-56 T 14-10-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 TSH58p_31195 fadefe091e3b1d07c208102645bc313f 297 Pfam PF02653 Branched-chain amino acid transport system / permease component 7 282 1.8E-27 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_01960 32b719f64a0a2ea4e15bf7c454146c7c 407 Gene3D G3DSA:2.160.20.10 41 400 1.6E-32 T 14-10-2018 IPR012334 Pectin lyase fold TSH58p_01960 32b719f64a0a2ea4e15bf7c454146c7c 407 Pfam PF13229 Right handed beta helix region 122 249 9.4E-9 T 14-10-2018 IPR039448 Right handed beta helix domain TSH58p_01960 32b719f64a0a2ea4e15bf7c454146c7c 407 Pfam PF13229 Right handed beta helix region 261 372 5.9E-10 T 14-10-2018 IPR039448 Right handed beta helix domain TSH58p_01960 32b719f64a0a2ea4e15bf7c454146c7c 407 SUPERFAMILY SSF51126 38 353 3.14E-37 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor TSH58p_01960 32b719f64a0a2ea4e15bf7c454146c7c 407 SMART SM00710 153 175 1.2 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_01960 32b719f64a0a2ea4e15bf7c454146c7c 407 SMART SM00710 339 362 2500.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_01960 32b719f64a0a2ea4e15bf7c454146c7c 407 SMART SM00710 129 151 3600.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_01960 32b719f64a0a2ea4e15bf7c454146c7c 407 SMART SM00710 177 199 2000.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_01960 32b719f64a0a2ea4e15bf7c454146c7c 407 SMART SM00710 202 226 7500.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_01960 32b719f64a0a2ea4e15bf7c454146c7c 407 SMART SM00710 264 285 2200.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_01960 32b719f64a0a2ea4e15bf7c454146c7c 407 SMART SM00710 286 308 1000.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat TSH58p_19090 a9a2ce52d4b3320a4fa3ea65004a7293 225 Pfam PF03741 Integral membrane protein TerC family 15 212 3.8E-42 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 TSH58p_19090 a9a2ce52d4b3320a4fa3ea65004a7293 225 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 13 212 2.2E-63 T 14-10-2018 IPR022301 Integral membrane protein YjbE TSH58p_09010 17c0b98404de381277d65195a942ff99 151 Pfam PF07681 DoxX 23 105 2.3E-19 T 14-10-2018 IPR032808 DoxX family TSH58p_32275 656d1fd1a102d0fea0932073d9d9e430 128 Pfam PF01850 PIN domain 4 112 1.3E-11 T 14-10-2018 IPR002716 PIN domain TSH58p_32275 656d1fd1a102d0fea0932073d9d9e430 128 Gene3D G3DSA:3.40.50.1010 1 125 2.3E-12 T 14-10-2018 TSH58p_32275 656d1fd1a102d0fea0932073d9d9e430 128 SUPERFAMILY SSF88723 1 121 1.32E-17 T 14-10-2018 IPR029060 PIN-like domain superfamily TSH58p_20545 6d4d1d30694d0a0b46fe72fd5c93c335 142 Gene3D G3DSA:3.30.450.20 2 140 3.9E-27 T 14-10-2018 TSH58p_20545 6d4d1d30694d0a0b46fe72fd5c93c335 142 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 7 130 6.5E-21 T 14-10-2018 IPR000014 PAS domain TSH58p_20545 6d4d1d30694d0a0b46fe72fd5c93c335 142 Pfam PF00989 PAS fold 7 119 3.1E-16 T 14-10-2018 IPR013767 PAS fold GO:0006355 TSH58p_20545 6d4d1d30694d0a0b46fe72fd5c93c335 142 SMART SM00091 5 71 2.5E-10 T 14-10-2018 IPR000014 PAS domain TSH58p_20545 6d4d1d30694d0a0b46fe72fd5c93c335 142 SUPERFAMILY SSF55785 16 132 5.09E-27 T 14-10-2018 IPR035965 PAS domain superfamily TSH58p_18080 fb9032048c6fac069d0957e18e058490 222 Gene3D G3DSA:3.50.30.100 1 194 5.0E-58 T 14-10-2018 TSH58p_18080 fb9032048c6fac069d0957e18e058490 222 SUPERFAMILY SSF89562 21 182 1.7E-51 T 14-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily TSH58p_18080 fb9032048c6fac069d0957e18e058490 222 Pfam PF03737 Aldolase/RraA 25 172 1.4E-43 T 14-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein TSH58p_01390 4d24da41912212bef3d4a487fde0c63f 294 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 278 1.6E-40 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_02970 471a440f85ff75095952d4b85b1f1727 348 Gene3D G3DSA:3.40.190.10 37 312 4.5E-73 T 14-10-2018 TSH58p_02970 471a440f85ff75095952d4b85b1f1727 348 SUPERFAMILY SSF53850 30 344 2.65E-56 T 14-10-2018 TSH58p_02970 471a440f85ff75095952d4b85b1f1727 348 Pfam PF13343 Bacterial extracellular solute-binding protein 82 309 3.5E-30 T 14-10-2018 TSH58p_02970 471a440f85ff75095952d4b85b1f1727 348 Gene3D G3DSA:3.40.190.10 134 314 4.5E-73 T 14-10-2018 TSH58p_14005 43b479f5716400a63add5459ab7b0ffd 175 SUPERFAMILY SSF102405 3 144 1.47E-22 T 14-10-2018 TSH58p_14005 43b479f5716400a63add5459ab7b0ffd 175 Gene3D G3DSA:3.40.50.450 1 172 1.4E-30 T 14-10-2018 TSH58p_19065 2de088a036f7e523e32a94aeda47f999 315 Pfam PF00892 EamA-like transporter family 13 145 6.7E-12 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_19065 2de088a036f7e523e32a94aeda47f999 315 Pfam PF00892 EamA-like transporter family 154 284 4.8E-9 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_19065 2de088a036f7e523e32a94aeda47f999 315 SUPERFAMILY SSF103481 48 148 1.83E-12 T 14-10-2018 TSH58p_19065 2de088a036f7e523e32a94aeda47f999 315 SUPERFAMILY SSF103481 188 289 2.62E-13 T 14-10-2018 TSH58p_03435 9af97dabb2d07e5113b615276779d6e3 281 Pfam PF05136 Phage portal protein, lambda family 113 280 2.3E-35 T 14-10-2018 IPR006429 Phage portal protein, lambda family GO:0005198|GO:0019068 TSH58p_11155 43f8efa44a1243907ea6a8f054eb23b0 523 SUPERFAMILY SSF50494 357 489 1.35E-7 T 14-10-2018 IPR009003 Peptidase S1, PA clan TSH58p_29470 b5cc15269d7f6ab746191ea162796492 176 SUPERFAMILY SSF55729 3 149 1.39E-32 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_29470 b5cc15269d7f6ab746191ea162796492 176 Gene3D G3DSA:3.40.630.30 3 176 2.0E-35 T 14-10-2018 TSH58p_29470 b5cc15269d7f6ab746191ea162796492 176 Pfam PF13302 Acetyltransferase (GNAT) domain 8 140 1.4E-22 T 14-10-2018 IPR000182 GNAT domain TSH58p_04505 04718ff610594a5b40c2c38a171743e4 277 Pfam PF02698 DUF218 domain 80 249 5.9E-24 T 14-10-2018 IPR003848 Domain of unknown function DUF218 TSH58p_13345 a968c7cf58fc9036eb218550965a8dd2 154 Pfam PF14343 PrcB C-terminal 87 138 1.2E-9 T 14-10-2018 IPR025748 PrcB C-terminal domain TSH58p_00375 7842151619bfd549d8dd25bf7f3b1d8e 392 Pfam PF10098 Uncharacterised protein conserved in bacteria (DUF2336) 91 352 3.0E-63 T 14-10-2018 IPR019285 Protein of unknown function DUF2336 TSH58p_32210 ec016fd5b900d4c9d526410a57cddbce 784 Gene3D G3DSA:3.20.20.140 289 536 4.4E-16 T 14-10-2018 TSH58p_32210 ec016fd5b900d4c9d526410a57cddbce 784 SUPERFAMILY SSF89550 294 532 8.24E-8 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TSH58p_17410 c68ad897c789bfa90ae37a8ac07b9878 283 Pfam PF12705 PD-(D/E)XK nuclease superfamily 13 270 2.1E-11 T 14-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type TSH58p_11200 01171c412d91c81052d08a351d85fa1e 256 Pfam PF02754 Cysteine-rich domain 139 223 1.1E-12 T 14-10-2018 IPR004017 Cysteine-rich domain TSH58p_11200 01171c412d91c81052d08a351d85fa1e 256 Pfam PF02754 Cysteine-rich domain 10 91 1.3E-12 T 14-10-2018 IPR004017 Cysteine-rich domain TSH58p_09980 4b40c606edccc5501390756c9fc41a52 591 Pfam PF09731 Mitochondrial inner membrane protein 385 568 3.7E-19 T 14-10-2018 IPR019133 Mitochondrial inner membrane protein Mitofilin Reactome: R-HSA-8949613 TSH58p_28570 f12715d1d411aa2ad8b4159f1cbaeceb 280 SUPERFAMILY SSF55729 4 259 2.47E-35 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_28570 f12715d1d411aa2ad8b4159f1cbaeceb 280 Gene3D G3DSA:3.40.630.90 136 280 3.5E-9 T 14-10-2018 TSH58p_28570 f12715d1d411aa2ad8b4159f1cbaeceb 280 Pfam PF00583 Acetyltransferase (GNAT) family 35 107 1.7E-6 T 14-10-2018 IPR000182 GNAT domain TSH58p_28570 f12715d1d411aa2ad8b4159f1cbaeceb 280 Gene3D G3DSA:3.40.630.30 1 130 1.1E-9 T 14-10-2018 TSH58p_31350 5168b9be17878a8eb1b5cf0ec99479c5 336 SUPERFAMILY SSF52540 72 326 2.13E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_31350 5168b9be17878a8eb1b5cf0ec99479c5 336 Pfam PF13614 AAA domain 72 249 1.6E-50 T 14-10-2018 IPR025669 AAA domain TSH58p_31350 5168b9be17878a8eb1b5cf0ec99479c5 336 Gene3D G3DSA:3.40.50.300 67 332 8.1E-68 T 14-10-2018 TSH58p_06730 f2e9d861613a2ee7529402625fa5770a 98 Pfam PF11740 Plasmid replication region DNA-binding N-term 10 46 2.2E-6 T 14-10-2018 IPR021104 KfrA, N-terminal DNA-binding domain TSH58p_16590 1f66aa287ee7d0066b320c4eb85d3739 149 Pfam PF14347 Domain of unknown function (DUF4399) 59 148 3.1E-38 T 14-10-2018 IPR025512 Domain of unknown function DUF4399 TSH58p_06450 12a88e0865623a40ae5cf349ba77cafe 382 Pfam PF02653 Branched-chain amino acid transport system / permease component 72 357 1.1E-39 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_08375 b5d18a8c79680575ffac9193226a0e6d 921 Pfam PF03200 Glycosyl hydrolase family 63 C-terminal domain 717 801 3.6E-5 T 14-10-2018 IPR031335 Glycosyl hydrolase family 63, C-terminal KEGG: 00510+3.2.1.106|MetaCyc: PWY-7918|MetaCyc: PWY-7919|Reactome: R-HSA-4793954|Reactome: R-HSA-532668 TSH58p_08375 b5d18a8c79680575ffac9193226a0e6d 921 SUPERFAMILY SSF48208 439 892 1.36E-45 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TSH58p_21765 ab74d79a39ea1b8e3ea49bfc09d981a6 328 Gene3D G3DSA:3.40.190.170 29 328 6.4E-91 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily TSH58p_21765 ab74d79a39ea1b8e3ea49bfc09d981a6 328 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 39 310 8.8E-40 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 TSH58p_00205 21bf6911cd2e23d5d057d20486dc2453 403 Pfam PF04577 Protein of unknown function (DUF563) 165 366 7.5E-43 T 14-10-2018 IPR007657 Glycosyltransferase 61 GO:0016757 TSH58p_16955 6e6bfd17f3481ee5c94d604c1765221a 150 Pfam PF03748 Flagellar basal body-associated protein FliL 56 149 1.3E-6 T 14-10-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 TSH58p_05430 ec35bfd5d404753b3723a697b1053684 221 Gene3D G3DSA:3.90.226.10 51 208 1.6E-14 T 14-10-2018 TSH58p_05430 ec35bfd5d404753b3723a697b1053684 221 SUPERFAMILY SSF52096 56 177 6.16E-15 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSH58p_05430 ec35bfd5d404753b3723a697b1053684 221 Pfam PF00574 Clp protease 84 163 4.8E-6 T 14-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA TSH58p_22935 70e0b5cbffe7fdeb3c992f9966ade8f7 332 Pfam PF02653 Branched-chain amino acid transport system / permease component 29 298 5.3E-40 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_11470 41a605e186de9cb47e91f21b5bf3c65a 197 Pfam PF12007 Protein of unknown function (DUF3501) 8 196 2.2E-61 T 14-10-2018 IPR021890 Protein of unknown function DUF3501 TSH58p_14505 f347ce6390a44d408779084662ecefbd 124 Pfam PF03788 LrgA family 12 105 1.2E-29 T 14-10-2018 IPR005538 LrgA/CidA family GO:0016021 TSH58p_14900 b0e5259d54e63f29f437cf2002d51397 259 Gene3D G3DSA:1.10.3720.10 48 244 3.9E-27 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_14900 b0e5259d54e63f29f437cf2002d51397 259 SUPERFAMILY SSF161098 50 236 4.45E-32 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_14900 b0e5259d54e63f29f437cf2002d51397 259 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 242 1.7E-26 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_23350 869b0432a13c98fd00dae06609f73cf9 196 Gene3D G3DSA:1.10.287.110 135 194 2.3E-6 T 14-10-2018 IPR036869 Chaperone J-domain superfamily TSH58p_23350 869b0432a13c98fd00dae06609f73cf9 196 SUPERFAMILY SSF46565 137 193 2.54E-7 T 14-10-2018 IPR036869 Chaperone J-domain superfamily TSH58p_06580 9d022d3a27580e2b2716679e961019e1 299 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 271 3.3E-33 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_04230 2c012f004f4c361d803f0169b45daeb0 486 Pfam PF16980 Putative citrate transport 45 485 1.9E-193 T 14-10-2018 IPR031566 Putative citrate transporter TSH58p_30340 71c0aa863dc027ae0172b9501d214a19 276 Pfam PF12679 ABC-2 family transporter protein 5 274 1.4E-45 T 14-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 TSH58p_14875 0c00207f17fa69934115973e59a484e1 86 Pfam PF11324 Protein of unknown function (DUF3126) 15 77 1.0E-27 T 14-10-2018 IPR021473 Protein of unknown function DUF3126 TSH58p_08995 8c4b9d773e42928a6bf7fc2de72688a6 218 Gene3D G3DSA:2.60.120.620 5 205 1.2E-8 T 14-10-2018 TSH58p_15460 cc729239024cd52f9772c8ecf332cdc8 632 Pfam PF02705 K+ potassium transporter 21 553 3.6E-217 T 14-10-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 TSH58p_15460 cc729239024cd52f9772c8ecf332cdc8 632 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 12 632 34.903 T 14-10-2018 IPR023051 Potassium uptake protein, low affinity, Kup TSH58p_05040 47a40d3be9b6fd960ac7ff57d1b34dfc 190 Gene3D G3DSA:3.40.50.880 2 186 2.1E-56 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_05040 47a40d3be9b6fd960ac7ff57d1b34dfc 190 Pfam PF01965 DJ-1/PfpI family 8 176 2.0E-56 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 TSH58p_05040 47a40d3be9b6fd960ac7ff57d1b34dfc 190 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 10 175 2.4E-51 T 14-10-2018 IPR006286 Deglycase PfpI TSH58p_05040 47a40d3be9b6fd960ac7ff57d1b34dfc 190 SUPERFAMILY SSF52317 7 177 3.34E-50 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like TSH58p_20705 e3fe68ea153b6557eef117528f89f2c7 340 Pfam PF00482 Type II secretion system (T2SS), protein F 173 300 2.2E-16 T 14-10-2018 IPR018076 Type II secretion system F domain TSH58p_00115 5d4dcfa3aee42338de77c00d74a88e7c 281 Gene3D G3DSA:3.30.1150.10 155 281 7.6E-32 T 14-10-2018 TSH58p_00115 5d4dcfa3aee42338de77c00d74a88e7c 281 SUPERFAMILY SSF74653 197 270 3.92E-15 T 14-10-2018 TSH58p_00115 5d4dcfa3aee42338de77c00d74a88e7c 281 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 202 278 2.6E-16 T 14-10-2018 IPR037682 TonB, C-terminal GO:0055085 TSH58p_00115 5d4dcfa3aee42338de77c00d74a88e7c 281 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 203 278 1.7E-17 T 14-10-2018 IPR006260 TonB/TolA, C-terminal TSH58p_09975 8eb2f818125d3ffbc9951b5349260bd7 251 Gene3D G3DSA:3.40.50.10090 1 115 3.5E-21 T 14-10-2018 TSH58p_09975 8eb2f818125d3ffbc9951b5349260bd7 251 SUPERFAMILY SSF69618 4 241 4.05E-43 T 14-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSH58p_09975 8eb2f818125d3ffbc9951b5349260bd7 251 Pfam PF02602 Uroporphyrinogen-III synthase HemD 17 238 8.0E-34 T 14-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSH58p_09975 8eb2f818125d3ffbc9951b5349260bd7 251 Gene3D G3DSA:3.40.50.10090 118 242 4.1E-13 T 14-10-2018 TSH58p_14760 e8fd633ac60d5a9b60ca296291c5c8fa 279 Gene3D G3DSA:3.90.1720.10 8 126 9.6E-11 T 14-10-2018 TSH58p_14760 e8fd633ac60d5a9b60ca296291c5c8fa 279 SUPERFAMILY SSF54001 33 150 6.18E-15 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily TSH58p_14760 e8fd633ac60d5a9b60ca296291c5c8fa 279 Pfam PF05257 CHAP domain 27 100 1.6E-6 T 14-10-2018 IPR007921 CHAP domain TSH58p_26695 27293de4e8ec3a451a887d28ccf0379f 254 Gene3D G3DSA:3.40.50.720 3 248 1.1E-61 T 14-10-2018 TSH58p_26695 27293de4e8ec3a451a887d28ccf0379f 254 SUPERFAMILY SSF51735 4 233 2.84E-60 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily TSH58p_26695 27293de4e8ec3a451a887d28ccf0379f 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 6.3E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_26695 27293de4e8ec3a451a887d28ccf0379f 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 6.3E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_26695 27293de4e8ec3a451a887d28ccf0379f 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 6.3E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_26695 27293de4e8ec3a451a887d28ccf0379f 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.3E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_26695 27293de4e8ec3a451a887d28ccf0379f 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 6.3E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_26695 27293de4e8ec3a451a887d28ccf0379f 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 6.3E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_26695 27293de4e8ec3a451a887d28ccf0379f 254 Pfam PF00106 short chain dehydrogenase 8 197 4.4E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSH58p_07200 6143bde05d9cb18376b79fc56c23c166 135 Gene3D G3DSA:3.30.2000.30 1 131 2.3E-35 T 14-10-2018 TSH58p_07200 6143bde05d9cb18376b79fc56c23c166 135 Pfam PF11367 Protein of unknown function (DUF3168) 16 126 4.6E-27 T 14-10-2018 IPR021508 Tail completion protein TSH58p_23510 905f092e7e669b5d75259c72c91f8c4e 418 Pfam PF04403 Paraquat-inducible protein A 252 405 1.1E-54 T 14-10-2018 IPR007498 Intermembrane transport protein PqiA-like TSH58p_23510 905f092e7e669b5d75259c72c91f8c4e 418 Pfam PF04403 Paraquat-inducible protein A 48 201 8.7E-42 T 14-10-2018 IPR007498 Intermembrane transport protein PqiA-like TSH58p_23510 905f092e7e669b5d75259c72c91f8c4e 418 TIGRFAM TIGR00155 pqiA_fam: integral membrane protein, PqiA family 6 405 3.6E-95 T 14-10-2018 IPR005219 Intermembrane transport protein PqiA-like, Enterobacteria-type TSH58p_06305 38ed1eee14e7ef964d6f7ac7ba6cfb71 372 Pfam PF05940 NnrS protein 14 366 1.3E-63 T 14-10-2018 IPR010266 NnrS TSH58p_12330 dedc0832047b60b56d425fafdca9e16b 169 SUPERFAMILY SSF56524 63 168 4.97E-15 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 TSH58p_12330 dedc0832047b60b56d425fafdca9e16b 169 Pfam PF00174 Oxidoreductase molybdopterin binding domain 70 138 6.6E-5 T 14-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 TSH58p_23715 60aa4345aee772e3040299aebae56f5c 436 Pfam PF12902 Ferritin-like 36 266 4.8E-39 T 14-10-2018 TSH58p_23715 60aa4345aee772e3040299aebae56f5c 436 Gene3D G3DSA:1.20.1260.10 21 277 3.5E-50 T 14-10-2018 IPR012347 Ferritin-like TSH58p_11115 3a05919141096f5e2aca3413ed0f302f 280 Pfam PF06724 Domain of Unknown Function (DUF1206) 102 173 9.3E-15 T 14-10-2018 IPR009597 Domain of unknown function DUF1206 TSH58p_11115 3a05919141096f5e2aca3413ed0f302f 280 Pfam PF06724 Domain of Unknown Function (DUF1206) 196 264 8.3E-19 T 14-10-2018 IPR009597 Domain of unknown function DUF1206 TSH58p_11115 3a05919141096f5e2aca3413ed0f302f 280 Pfam PF06724 Domain of Unknown Function (DUF1206) 20 86 2.2E-20 T 14-10-2018 IPR009597 Domain of unknown function DUF1206 TSH58p_09170 87781ef45b0bb5d1c0ea075d639b75c0 221 Gene3D G3DSA:2.30.30.40 154 219 2.6E-5 T 14-10-2018 TSH58p_09170 87781ef45b0bb5d1c0ea075d639b75c0 221 Pfam PF06347 Bacterial SH3 domain 165 217 1.6E-4 T 14-10-2018 IPR010466 Protein of unknown function DUF1058 TSH58p_17560 63dcac6bc9a3edabaca7aeedbd2a5b5f 271 Pfam PF06054 Competence protein CoiA-like family 22 141 3.0E-21 T 14-10-2018 IPR010330 Competence-induced protein CoiA-like TSH58p_19780 e5128c5cea46b64520e9f781e88a83cc 320 Pfam PF10134 Replication initiator protein A 34 265 6.3E-53 T 14-10-2018 IPR018777 Replication initiator protein A TSH58p_31095 570353f2efe71fbc7827c9c42ea1ea97 382 Pfam PF03929 PepSY-associated TM region 12 359 4.2E-57 T 14-10-2018 IPR005625 PepSY-associated TM protein TSH58p_14660 a9ec9930951eda34997dbabfeb0faa9a 101 Pfam PF09923 Uncharacterized protein conserved in bacteria (DUF2155) 7 98 6.0E-36 T 14-10-2018 IPR019225 Protein of unknown function DUF2155 TSH58p_00275 c73265e71ed546650f29973ad966a4a7 168 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 21 158 9.8E-17 T 14-10-2018 IPR009936 Protein of unknown function DUF1468 TSH58p_23990 0e31fbb96688ac56d24a0bdf3539a60b 89 Pfam PF13467 Ribbon-helix-helix domain 7 70 7.2E-23 T 14-10-2018 IPR027373 Ribbon-helix-helix domain TSH58p_23990 0e31fbb96688ac56d24a0bdf3539a60b 89 Gene3D G3DSA:1.10.3990.20 1 89 6.0E-19 T 14-10-2018 IPR038268 Ribbon-helix-helix domain superfamily TSH58p_02235 a6c92b9f8cafebe9eafc31254cb10fbe 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 310 7.8E-42 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_02235 a6c92b9f8cafebe9eafc31254cb10fbe 312 Gene3D G3DSA:1.10.3720.10 86 302 3.4E-25 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_02235 a6c92b9f8cafebe9eafc31254cb10fbe 312 SUPERFAMILY SSF161098 90 296 6.15E-23 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_22110 822e6c9bdf24400c925626175ae88b02 107 Pfam PF13493 Domain of unknown function (DUF4118) 18 85 3.7E-10 T 14-10-2018 IPR025201 Sensor protein KdpD, transmembrane domain TSH58p_23295 2f7b9152440f32a27e6b47bd4112017b 1382 Pfam PF14331 ImcF-related N-terminal domain 155 374 6.1E-37 T 14-10-2018 IPR025743 ImcF-related, N-terminal domain TSH58p_26675 3e645b36591798dd8d70b50fc8e08512 394 SUPERFAMILY SSF56529 167 369 4.32E-23 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TSH58p_26675 3e645b36591798dd8d70b50fc8e08512 394 Gene3D G3DSA:3.90.850.10 155 371 3.7E-39 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TSH58p_10010 420affd8a2558373467642b1c5a0d3bb 89 Pfam PF11154 Protein of unknown function (DUF2934) 8 42 5.1E-14 T 14-10-2018 IPR021327 Protein of unknown function DUF2934 TSH58p_16620 f0ee481a5018f9908194bce3baa31661 437 Pfam PF14326 Domain of unknown function (DUF4384) 308 376 2.4E-9 T 14-10-2018 IPR025493 Domain of unknown function DUF4384 TSH58p_11005 77d647982b2ad174b095008c4cd2de75 268 Gene3D G3DSA:3.40.50.300 4 267 1.2E-81 T 14-10-2018 TSH58p_11005 77d647982b2ad174b095008c4cd2de75 268 SUPERFAMILY SSF52540 12 264 1.04E-69 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_11005 77d647982b2ad174b095008c4cd2de75 268 Pfam PF13614 AAA domain 13 188 1.1E-62 T 14-10-2018 IPR025669 AAA domain TSH58p_00220 93f7f5d2c16a432c1bf1da1b97497408 155 Pfam PF13430 Domain of unknown function (DUF4112) 25 126 4.2E-31 T 14-10-2018 IPR025187 Protein of unknown function DUF4112 TSH58p_26225 5e6aa50d718379cbb11d2e1e50915f71 339 Gene3D G3DSA:1.10.3470.10 10 338 4.2E-80 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_26225 5e6aa50d718379cbb11d2e1e50915f71 339 SUPERFAMILY SSF81345 10 333 6.02E-66 T 14-10-2018 IPR037294 ABC transporter, BtuC-like TSH58p_26225 5e6aa50d718379cbb11d2e1e50915f71 339 Pfam PF01032 FecCD transport family 24 333 4.5E-75 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TSH58p_32385 d8b161b63bcfb2e890dea9c507069da7 284 SUPERFAMILY SSF53850 49 253 2.56E-40 T 14-10-2018 TSH58p_32385 d8b161b63bcfb2e890dea9c507069da7 284 SMART SM00062 48 271 8.3E-19 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_32385 d8b161b63bcfb2e890dea9c507069da7 284 Gene3D G3DSA:3.40.190.10 135 224 3.6E-48 T 14-10-2018 TSH58p_32385 d8b161b63bcfb2e890dea9c507069da7 284 Gene3D G3DSA:3.40.190.10 41 255 3.6E-48 T 14-10-2018 TSH58p_32385 d8b161b63bcfb2e890dea9c507069da7 284 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 49 251 3.3E-31 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSH58p_11645 066ffef33a772deb12023cfdf67af16e 174 Pfam PF05751 FixH 22 171 8.5E-33 T 14-10-2018 IPR008620 Nitrogen fixation protein FixH TSH58p_00715 796ea3e88dc2a496eedf4c3935e76cf9 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 254 3.0E-11 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_00715 796ea3e88dc2a496eedf4c3935e76cf9 265 Gene3D G3DSA:1.10.3720.10 2 258 1.5E-49 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_00715 796ea3e88dc2a496eedf4c3935e76cf9 265 SUPERFAMILY SSF161098 5 264 9.29E-60 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_06135 64b8c5696f9c2c05ea01f3328569d752 139 Gene3D G3DSA:3.10.50.30 56 135 3.7E-18 T 14-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 TSH58p_06135 64b8c5696f9c2c05ea01f3328569d752 139 SUPERFAMILY SSF54534 59 131 4.58E-13 T 14-10-2018 TSH58p_06135 64b8c5696f9c2c05ea01f3328569d752 139 Pfam PF14760 Rnk N-terminus 11 49 2.3E-7 T 14-10-2018 IPR029462 Regulator of nucleoside diphosphate kinase, N-terminal domain TSH58p_06135 64b8c5696f9c2c05ea01f3328569d752 139 PIRSF PIRSF006092 27 134 1.0E-16 T 14-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 TSH58p_06135 64b8c5696f9c2c05ea01f3328569d752 139 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 60 131 3.6E-15 T 14-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 TSH58p_29605 4669b1d2a0a3750db63fce4b84fec059 196 SUPERFAMILY SSF81342 17 193 8.63E-34 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 TSH58p_29605 4669b1d2a0a3750db63fce4b84fec059 196 Pfam PF01292 Prokaryotic cytochrome b561 22 192 1.7E-27 T 14-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 TSH58p_03270 514520eb9990bf5788fc96c8437695d9 98 Pfam PF06945 Protein of unknown function (DUF1289) 8 53 9.4E-16 T 14-10-2018 IPR010710 Protein of unknown function DUF1289 TSH58p_06870 49e332043be5f28b964c0a8cb994100a 205 Pfam PF06242 Protein of unknown function (DUF1013) 34 169 1.7E-63 T 14-10-2018 IPR010421 Protein of unknown function DUF1013 TSH58p_20215 6ab51d893a3d401a9d4e24ce7065dcf2 166 Pfam PF03748 Flagellar basal body-associated protein FliL 72 166 1.3E-12 T 14-10-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 TSH58p_03170 d02945ae57bcfa069b9cf21db752d805 167 Pfam PF14196 L-2-amino-thiazoline-4-carboxylic acid hydrolase 20 160 2.4E-37 T 14-10-2018 IPR026002 L-2-amino-thiazoline-4-carboxylic acid hydrolase TSH58p_25365 a026fb3fbd215ccc45c35f02ad03d786 320 Pfam PF16154 Domain of unknown function (DUF4862) 10 304 4.3E-77 T 14-10-2018 IPR032344 Protein of unknown function DUF4862 TSH58p_15010 dc5bda81d8aafdea14daf58af19cae18 613 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 278 7.5E-41 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_15010 dc5bda81d8aafdea14daf58af19cae18 613 Pfam PF02653 Branched-chain amino acid transport system / permease component 334 591 1.7E-33 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_00870 a904f9060bc14858b2a24511f462e1a4 262 Pfam PF12570 Protein of unknown function (DUF3750) 53 185 2.2E-49 T 14-10-2018 IPR022224 Protein of unknown function DUF3750 TSH58p_28770 c7c892c684cdca632ef08dda164df5a7 260 SUPERFAMILY SSF53335 23 216 7.97E-22 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_28770 c7c892c684cdca632ef08dda164df5a7 260 Gene3D G3DSA:3.40.50.150 12 182 7.4E-16 T 14-10-2018 TSH58p_28770 c7c892c684cdca632ef08dda164df5a7 260 Pfam PF08241 Methyltransferase domain 83 131 2.5E-6 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TSH58p_13785 45034c106b7ce82d77823f3600e7ae00 457 Pfam PF00990 Diguanylate cyclase, GGDEF domain 36 167 1.4E-4 T 14-10-2018 IPR000160 GGDEF domain TSH58p_13785 45034c106b7ce82d77823f3600e7ae00 457 SUPERFAMILY SSF55073 38 149 2.2E-5 T 14-10-2018 IPR029787 Nucleotide cyclase TSH58p_13785 45034c106b7ce82d77823f3600e7ae00 457 Gene3D G3DSA:3.30.70.270 32 176 6.5E-7 T 14-10-2018 TSH58p_05365 f1a15345d6bfc30cf6428a573e794b00 170 Pfam PF07883 Cupin domain 66 137 1.3E-19 T 14-10-2018 IPR013096 Cupin 2, conserved barrel TSH58p_05365 f1a15345d6bfc30cf6428a573e794b00 170 SUPERFAMILY SSF51182 37 154 2.65E-26 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily TSH58p_05365 f1a15345d6bfc30cf6428a573e794b00 170 Gene3D G3DSA:2.60.120.10 20 170 1.9E-49 T 14-10-2018 IPR014710 RmlC-like jelly roll fold TSH58p_10965 191c04d172669b68d7bb40030a8689c4 385 SUPERFAMILY SSF56935 18 385 2.23E-32 T 14-10-2018 TSH58p_10965 191c04d172669b68d7bb40030a8689c4 385 Pfam PF13609 Gram-negative porin 10 357 1.1E-47 T 14-10-2018 TSH58p_10965 191c04d172669b68d7bb40030a8689c4 385 Gene3D G3DSA:2.40.160.10 28 368 8.4E-42 T 14-10-2018 IPR023614 Porin domain superfamily TSH58p_22555 ecc1fcc71e59c5244a3977daf0adac4d 85 Gene3D G3DSA:1.10.260.40 2 78 3.4E-11 T 14-10-2018 TSH58p_13195 96d59c8f34f06807dffaba069950135a 146 Gene3D G3DSA:3.10.590.10 6 139 2.7E-27 T 14-10-2018 TSH58p_13195 96d59c8f34f06807dffaba069950135a 146 Hamap MF_00771 UPF0310 protein . 7 141 28.731 T 14-10-2018 IPR022996 Uncharacterised protein family UPF0310 TSH58p_13195 96d59c8f34f06807dffaba069950135a 146 Pfam PF01878 EVE domain 9 139 3.9E-15 T 14-10-2018 IPR002740 EVE domain TSH58p_13195 96d59c8f34f06807dffaba069950135a 146 SUPERFAMILY SSF88697 10 141 5.47E-29 T 14-10-2018 IPR015947 PUA-like superfamily TSH58p_02805 5976454c37261016c31315c7443a1637 444 Pfam PF04932 O-Antigen ligase 200 359 1.5E-14 T 14-10-2018 IPR007016 O-antigen ligase-related TSH58p_02845 8b7a2f5aada3672d469f28119f396da0 268 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 59 236 7.4E-47 T 14-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 TSH58p_02845 8b7a2f5aada3672d469f28119f396da0 268 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 63 232 3.2E-56 T 14-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 TSH58p_22945 b597705e1a18851a397c6fc2c5ed4e92 414 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 308 321 5.2E-8 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_22945 b597705e1a18851a397c6fc2c5ed4e92 414 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 46 62 5.2E-8 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_22945 b597705e1a18851a397c6fc2c5ed4e92 414 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 68 84 5.2E-8 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSH58p_22945 b597705e1a18851a397c6fc2c5ed4e92 414 Gene3D G3DSA:3.40.50.2300 47 370 5.7E-70 T 14-10-2018 TSH58p_22945 b597705e1a18851a397c6fc2c5ed4e92 414 Pfam PF13458 Periplasmic binding protein 46 387 9.9E-50 T 14-10-2018 IPR028081 Leucine-binding protein domain TSH58p_22945 b597705e1a18851a397c6fc2c5ed4e92 414 SUPERFAMILY SSF53822 46 411 2.35E-66 T 14-10-2018 IPR028082 Periplasmic binding protein-like I TSH58p_22945 b597705e1a18851a397c6fc2c5ed4e92 414 Gene3D G3DSA:3.40.50.2300 167 303 5.7E-70 T 14-10-2018 TSH58p_30510 d92ac8ecf9ebc92f0c8346b67c619733 174 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 31 162 5.5E-28 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ TSH58p_22500 797f2ef7319633ed7498e63fd5d6f4cb 317 Pfam PF05036 Sporulation related domain 236 316 6.3E-11 T 14-10-2018 IPR007730 Sporulation-like domain GO:0042834 TSH58p_22500 797f2ef7319633ed7498e63fd5d6f4cb 317 SUPERFAMILY SSF110997 235 316 2.62E-5 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 TSH58p_01845 20c6a56aa184e38b64042205dd2da0b9 377 Pfam PF03916 Polysulphide reductase, NrfD 8 312 2.5E-35 T 14-10-2018 IPR005614 NrfD family TSH58p_16500 7c7674008a410e8b84fc9a20e2c7ede7 274 SMART SM00849 27 216 2.4E-7 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_16500 7c7674008a410e8b84fc9a20e2c7ede7 274 Pfam PF12706 Beta-lactamase superfamily domain 39 239 1.4E-31 T 14-10-2018 IPR001279 Metallo-beta-lactamase TSH58p_16500 7c7674008a410e8b84fc9a20e2c7ede7 274 SUPERFAMILY SSF56281 5 273 1.18E-52 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_16500 7c7674008a410e8b84fc9a20e2c7ede7 274 Gene3D G3DSA:3.60.15.10 4 274 5.6E-53 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSH58p_07930 e251bef7327d8bd35a6c0df1feaeb551 154 Pfam PF00430 ATP synthase B/B' CF(0) 2 129 5.0E-26 T 14-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 TSH58p_07930 e251bef7327d8bd35a6c0df1feaeb551 154 Hamap MF_01398 ATP synthase subunit b [atpF]. 2 131 10.584 T 14-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 TSH58p_17205 d40cfca75d606f51e39f3c557e027b3c 154 PIRSF PIRSF024492 4 152 2.9E-28 T 14-10-2018 IPR014519 Uncharacterised conserved protein UCP024492 TSH58p_17205 d40cfca75d606f51e39f3c557e027b3c 154 Pfam PF04343 Protein of unknown function, DUF488 18 135 1.7E-26 T 14-10-2018 IPR007438 Protein of unknown function DUF488 TSH58p_24750 79a8268919b2659a4aa186676a9f91dd 367 SUPERFAMILY SSF53955 123 263 1.36E-9 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily TSH58p_24750 79a8268919b2659a4aa186676a9f91dd 367 Gene3D G3DSA:1.10.530.10 111 312 1.6E-44 T 14-10-2018 TSH58p_27175 f88a10de0fb3d7b2dd0d0670f9b2f1c2 128 Gene3D G3DSA:1.10.3990.20 17 108 6.3E-14 T 14-10-2018 IPR038268 Ribbon-helix-helix domain superfamily TSH58p_27175 f88a10de0fb3d7b2dd0d0670f9b2f1c2 128 Pfam PF13467 Ribbon-helix-helix domain 21 92 1.4E-18 T 14-10-2018 IPR027373 Ribbon-helix-helix domain TSH58p_14065 9ae4fd843a38c6ea32c3421b96b3731a 370 Pfam PF01594 AI-2E family transporter 37 358 1.1E-45 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like TSH58p_07240 00d8b85cb15620c9512e6aa8897ad98a 545 Gene3D G3DSA:3.40.50.300 12 218 7.7E-20 T 14-10-2018 TSH58p_07240 00d8b85cb15620c9512e6aa8897ad98a 545 Pfam PF03354 Phage Terminase 44 528 9.6E-65 T 14-10-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type TSH58p_04035 346d8df10d9ea2f94e7f3328b85eee10 318 Pfam PF09991 Predicted membrane protein (DUF2232) 19 295 1.7E-9 T 14-10-2018 IPR018710 Protein of unknown function DUF2232 TSH58p_29875 60f15effb937e5855877907e00d56b12 338 Pfam PF00676 Dehydrogenase E1 component 31 327 1.9E-102 T 14-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 TSH58p_29875 60f15effb937e5855877907e00d56b12 338 SUPERFAMILY SSF52518 20 337 3.07E-107 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold TSH58p_29875 60f15effb937e5855877907e00d56b12 338 Gene3D G3DSA:3.40.50.970 2 338 8.5E-137 T 14-10-2018 TSH58p_29875 60f15effb937e5855877907e00d56b12 338 TIGRFAM TIGR03182 PDH_E1_alph_y: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 23 335 1.8E-154 T 14-10-2018 IPR017597 Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y GO:0004739|GO:0006086|GO:0043231 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-70268 TSH58p_18745 509ca6fe82aa57d1dbac31d96a910f17 100 Pfam PF13466 STAS domain 16 94 4.2E-12 T 14-10-2018 IPR002645 STAS domain TSH58p_18745 509ca6fe82aa57d1dbac31d96a910f17 100 Gene3D G3DSA:3.30.750.24 2 100 8.1E-12 T 14-10-2018 IPR036513 STAS domain superfamily TSH58p_18745 509ca6fe82aa57d1dbac31d96a910f17 100 SUPERFAMILY SSF52091 1 99 5.49E-15 T 14-10-2018 IPR036513 STAS domain superfamily TSH58p_18100 40eb1bbd972d57b22a35c6caf49898bd 230 Pfam PF09335 SNARE associated Golgi protein 69 185 9.6E-24 T 14-10-2018 IPR032816 SNARE associated Golgi protein TSH58p_20535 3d05ddb8140eeef41e047c1e95460fa9 86 SUPERFAMILY SSF46785 37 85 2.16E-5 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_23420 dc0434fa36143302add183b7eca9e3cd 541 Pfam PF03929 PepSY-associated TM region 12 371 1.9E-55 T 14-10-2018 IPR005625 PepSY-associated TM protein TSH58p_05070 a363dd6615b9de6c318cc552a12ab0b7 249 Pfam PF01925 Sulfite exporter TauE/SafE 8 241 2.8E-33 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TSH58p_06860 e9ea4084848377c9b07883d4cd6583a1 62 Pfam PF06698 Protein of unknown function (DUF1192) 4 59 1.1E-21 T 14-10-2018 IPR009579 Protein of unknown function DUF1192 TSH58p_14570 ed17ae576d44c461068fdcf1819d2ee8 97 Pfam PF11154 Protein of unknown function (DUF2934) 5 39 2.2E-13 T 14-10-2018 IPR021327 Protein of unknown function DUF2934 TSH58p_19175 8e65b5af65f023227d1057f0e67a12e2 261 SUPERFAMILY SSF53955 57 184 1.03E-9 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily TSH58p_05425 52bed400c13ac067c330f278da01b6d0 245 SUPERFAMILY SSF53474 5 179 1.91E-19 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_05425 52bed400c13ac067c330f278da01b6d0 245 Gene3D G3DSA:3.40.50.1820 1 190 3.5E-26 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold TSH58p_03430 584f47aa415dd432ce2305bb806c3d94 301 Pfam PF05876 Phage terminase large subunit (GpA) 108 243 2.2E-19 T 14-10-2018 IPR008866 Bacteriophage lambda, GpA TSH58p_19230 5ef9a3c9b9531f091e22c6027130e8be 130 SUPERFAMILY SSF160214 80 109 4.71E-5 T 14-10-2018 IPR035924 FlaG-like superfamily TSH58p_20875 a3e91b64e1c65b726d6ecd1184739e4d 169 Pfam PF13801 Heavy-metal resistance 35 160 8.8E-24 T 14-10-2018 IPR025961 Heavy-metal resistance protein TSH58p_20875 a3e91b64e1c65b726d6ecd1184739e4d 169 Gene3D G3DSA:1.20.120.1490 70 166 6.7E-6 T 14-10-2018 TSH58p_23875 4550b1b21f110b7b92d8e720cbf0e658 75 Pfam PF01206 Sulfurtransferase TusA 5 73 1.3E-21 T 14-10-2018 IPR001455 TusA-like domain TSH58p_23875 4550b1b21f110b7b92d8e720cbf0e658 75 Gene3D G3DSA:3.30.110.40 1 74 4.1E-28 T 14-10-2018 IPR036868 TusA-like domain superfamily TSH58p_23875 4550b1b21f110b7b92d8e720cbf0e658 75 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 6 30 - T 14-10-2018 IPR001455 TusA-like domain TSH58p_23875 4550b1b21f110b7b92d8e720cbf0e658 75 SUPERFAMILY SSF64307 3 73 2.09E-22 T 14-10-2018 IPR036868 TusA-like domain superfamily TSH58p_07570 c18deb0c08340a127bd72567e8d9ae44 98 Pfam PF04319 NifZ domain 18 88 1.3E-29 T 14-10-2018 IPR007415 Nitrogenase MoFe maturation protein, NifZ GO:0009399 TSH58p_19935 3154c79fb9ebe98ad655422f4bb5f243 463 Gene3D G3DSA:3.40.190.10 38 311 9.9E-45 T 14-10-2018 TSH58p_19935 3154c79fb9ebe98ad655422f4bb5f243 463 SUPERFAMILY SSF53850 35 316 1.91E-48 T 14-10-2018 TSH58p_19935 3154c79fb9ebe98ad655422f4bb5f243 463 Pfam PF13343 Bacterial extracellular solute-binding protein 84 300 1.9E-26 T 14-10-2018 TSH58p_19935 3154c79fb9ebe98ad655422f4bb5f243 463 Gene3D G3DSA:3.40.190.10 139 255 9.9E-45 T 14-10-2018 TSH58p_27490 f72a88263e7e9c2ecdc510cea945e58e 60 Pfam PF12073 Protein of unknown function (DUF3553) 5 53 2.1E-27 T 14-10-2018 IPR021938 Protein of unknown function DUF3553 TSH58p_10430 482ae6cd85e9e33541b95adebface1c1 206 Pfam PF03729 Short repeat of unknown function (DUF308) 87 152 2.8E-11 T 14-10-2018 IPR005325 Protein of unknown function DUF308, membrane TSH58p_10430 482ae6cd85e9e33541b95adebface1c1 206 Pfam PF03729 Short repeat of unknown function (DUF308) 141 188 9.5E-4 T 14-10-2018 IPR005325 Protein of unknown function DUF308, membrane TSH58p_10430 482ae6cd85e9e33541b95adebface1c1 206 Pfam PF03729 Short repeat of unknown function (DUF308) 29 79 3.1E-8 T 14-10-2018 IPR005325 Protein of unknown function DUF308, membrane TSH58p_09630 640873cc8d541a8183011dd8258bd308 101 Gene3D G3DSA:3.30.750.24 1 101 5.6E-22 T 14-10-2018 IPR036513 STAS domain superfamily TSH58p_09630 640873cc8d541a8183011dd8258bd308 101 Pfam PF13466 STAS domain 14 93 5.7E-16 T 14-10-2018 IPR002645 STAS domain TSH58p_09630 640873cc8d541a8183011dd8258bd308 101 SUPERFAMILY SSF52091 1 99 5.49E-22 T 14-10-2018 IPR036513 STAS domain superfamily TSH58p_09630 640873cc8d541a8183011dd8258bd308 101 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 4 101 3.9E-18 T 14-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 TSH58p_05785 ce3385bec26fd37c22945ceb9c68c5dd 295 SUPERFAMILY SSF103481 203 283 2.35E-9 T 14-10-2018 TSH58p_05785 ce3385bec26fd37c22945ceb9c68c5dd 295 SUPERFAMILY SSF103481 39 133 9.02E-13 T 14-10-2018 TSH58p_05785 ce3385bec26fd37c22945ceb9c68c5dd 295 Pfam PF00892 EamA-like transporter family 143 282 5.5E-14 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_05785 ce3385bec26fd37c22945ceb9c68c5dd 295 Pfam PF00892 EamA-like transporter family 8 133 3.5E-18 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_17650 a666b0c161f6d65eb82457c35dbfe9d6 719 Pfam PF06791 Prophage tail length tape measure protein 167 338 4.0E-12 T 14-10-2018 IPR009628 Bacteriophage lambda, GpH, tail tape measure, N-terminal TSH58p_01185 0b1b58b882a0016a11f7a6bb3f6bdf9b 125 SUPERFAMILY SSF55248 11 100 4.32E-26 T 14-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 TSH58p_01185 0b1b58b882a0016a11f7a6bb3f6bdf9b 125 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 9 97 2.1E-25 T 14-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 TSH58p_01185 0b1b58b882a0016a11f7a6bb3f6bdf9b 125 Gene3D G3DSA:3.30.1360.20 8 106 1.6E-25 T 14-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 TSH58p_01255 2b0c3d2b125f0db9832f29188dd3e117 26 TIGRFAM TIGR02107 PQQ_syn_pqqA: coenzyme PQQ precursor peptide PqqA 4 24 7.1E-6 T 14-10-2018 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 TSH58p_01255 2b0c3d2b125f0db9832f29188dd3e117 26 Pfam PF08042 PqqA family 3 21 5.6E-5 T 14-10-2018 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 TSH58p_07295 834e7d44cba9cbf337c1f22ad39dd613 178 Gene3D G3DSA:3.40.630.30 22 167 3.0E-14 T 14-10-2018 TSH58p_07295 834e7d44cba9cbf337c1f22ad39dd613 178 SUPERFAMILY SSF55729 24 160 1.89E-14 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_07295 834e7d44cba9cbf337c1f22ad39dd613 178 Pfam PF13508 Acetyltransferase (GNAT) domain 75 158 1.2E-9 T 14-10-2018 IPR000182 GNAT domain TSH58p_04770 3a9f141adbf15d16399a0faeed21be39 146 Pfam PF14325 Domain of unknown function (DUF4383) 4 130 7.5E-37 T 14-10-2018 IPR025492 Protein of unknown function DUF4383 TSH58p_31950 7adbebd930408c22a120dbe132b37b06 118 SUPERFAMILY SSF142764 5 77 1.96E-8 T 14-10-2018 TSH58p_31950 7adbebd930408c22a120dbe132b37b06 118 Gene3D G3DSA:3.40.50.10840 1 84 4.7E-7 T 14-10-2018 IPR037051 Four-carbon acid sugar kinase, N-terminal domain superfamily TSH58p_13995 ef423163d2e1f91fe1de0261f7de2dcb 518 Pfam PF04293 SpoVR like protein 17 455 1.0E-167 T 14-10-2018 IPR007390 Sporulation stage V, protein R TSH58p_28925 bf0fc3beef40b921faff771e1064dc98 309 Pfam PF03547 Membrane transport protein 163 303 1.4E-10 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 TSH58p_05995 2644887316c728e4a1287cef9a58c5ee 151 Gene3D G3DSA:3.10.129.10 1 146 1.9E-47 T 14-10-2018 TSH58p_05995 2644887316c728e4a1287cef9a58c5ee 151 SUPERFAMILY SSF54637 2 146 1.36E-36 T 14-10-2018 IPR029069 HotDog domain superfamily TSH58p_05995 2644887316c728e4a1287cef9a58c5ee 151 Pfam PF01575 MaoC like domain 12 122 1.7E-20 T 14-10-2018 IPR002539 MaoC-like dehydratase domain TSH58p_18330 39f70147efcf72b7f575c375c827dc30 201 Pfam PF08241 Methyltransferase domain 28 93 3.0E-12 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TSH58p_18330 39f70147efcf72b7f575c375c827dc30 201 SUPERFAMILY SSF53335 4 177 4.94E-21 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_02525 adc3a340fe8593f63f6e29ad82e6de30 545 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 24 302 4.9E-11 T 14-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD TSH58p_17025 00e8d91d23f934da44a5b5ef322820a7 638 Pfam PF01594 AI-2E family transporter 184 379 1.7E-36 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like TSH58p_17025 00e8d91d23f934da44a5b5ef322820a7 638 Pfam PF01594 AI-2E family transporter 30 136 1.0E-13 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like TSH58p_15875 6f581a39fe66d26c5c6e7990b6ddc209 364 SUPERFAMILY SSF52172 16 149 5.27E-29 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_15875 6f581a39fe66d26c5c6e7990b6ddc209 364 SMART SM00448 15 140 5.0E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_15875 6f581a39fe66d26c5c6e7990b6ddc209 364 Pfam PF00072 Response regulator receiver domain 17 137 8.6E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_15875 6f581a39fe66d26c5c6e7990b6ddc209 364 Gene3D G3DSA:3.40.50.12740 15 287 1.5E-25 T 14-10-2018 TSH58p_10025 6767b11b0a442a4af31c10238e5e4ce4 153 Gene3D G3DSA:1.20.1270.390 21 109 3.5E-18 T 14-10-2018 TSH58p_10025 6767b11b0a442a4af31c10238e5e4ce4 153 Pfam PF14346 Domain of unknown function (DUF4398) 13 105 4.3E-22 T 14-10-2018 IPR025511 Domain of unknown function DUF4398 TSH58p_15605 0b241484812593c05e3cf9ff7e7f3e29 263 Pfam PF13490 Putative zinc-finger 12 36 4.6E-5 T 14-10-2018 IPR027383 Putative zinc-finger TSH58p_14275 428f83135d3939b700c28a3cf417052d 123 Pfam PF01814 Hemerythrin HHE cation binding domain 4 116 2.6E-12 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 TSH58p_14275 428f83135d3939b700c28a3cf417052d 123 ProSitePatterns PS00550 Hemerythrin family signature. 48 71 - T 14-10-2018 IPR016131 Haemerythrin, iron-binding site GO:0046872 TSH58p_14275 428f83135d3939b700c28a3cf417052d 123 SUPERFAMILY SSF47188 1 119 2.88E-28 T 14-10-2018 IPR035938 Hemerythrin-like superfamily TSH58p_14275 428f83135d3939b700c28a3cf417052d 123 Gene3D G3DSA:1.20.120.50 1 123 8.4E-34 T 14-10-2018 IPR035938 Hemerythrin-like superfamily TSH58p_14275 428f83135d3939b700c28a3cf417052d 123 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 2 119 1.0E-31 T 14-10-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 TSH58p_26715 d9443499e1566401bdb5becb864aa076 98 Pfam PF12365 Protein of unknown function (DUF3649) 70 95 4.5E-9 T 14-10-2018 IPR022109 Protein of unknown function DUF3649 TSH58p_08990 a0f87128536f69b2243e49be0c8e2698 329 Pfam PF06258 Mitochondrial fission ELM1 19 320 8.5E-110 T 14-10-2018 IPR009367 Mitochondrial fission protein ELM1-like TSH58p_24130 cdc15160d498ffbba3e1ffa914b8cd7f 111 Pfam PF07372 Protein of unknown function (DUF1491) 5 106 6.2E-34 T 14-10-2018 IPR009964 Protein of unknown function DUF1491 TSH58p_24130 cdc15160d498ffbba3e1ffa914b8cd7f 111 Gene3D G3DSA:3.40.1530.20 2 110 1.5E-29 T 14-10-2018 TSH58p_28475 7e0b796bb600970867fa8c9dabe09c87 223 Pfam PF09601 Protein of unknown function (DUF2459) 46 214 2.8E-51 T 14-10-2018 IPR011727 Conserved hypothetical protein CHP02117 TSH58p_28475 7e0b796bb600970867fa8c9dabe09c87 223 TIGRFAM TIGR02117 chp_urease_rgn: conserved hypothetical protein 24 217 1.6E-51 T 14-10-2018 IPR011727 Conserved hypothetical protein CHP02117 TSH58p_06915 1d29cb74cc2bf9c4f382b4915b119a03 66 Gene3D G3DSA:1.20.58.660 3 61 7.5E-8 T 14-10-2018 TSH58p_06915 1d29cb74cc2bf9c4f382b4915b119a03 66 Pfam PF04325 Protein of unknown function (DUF465) 11 56 1.9E-16 T 14-10-2018 IPR007420 Protein of unknown function DUF465 TSH58p_06250 c7002b081b20ce5cd4a156d88e2c1418 163 PIRSF PIRSF016789 19 138 9.2E-32 T 14-10-2018 IPR007401 Protein of unknown function DUF454 TSH58p_06250 c7002b081b20ce5cd4a156d88e2c1418 163 Pfam PF04304 Protein of unknown function (DUF454) 20 133 2.2E-35 T 14-10-2018 IPR007401 Protein of unknown function DUF454 TSH58p_09070 5edcbe7e09225eea351a6986f9fc7d04 79 Pfam PF13773 Domain of unknown function (DUF4170) 4 71 6.1E-35 T 14-10-2018 IPR025226 Protein of unknown function DUF4170 TSH58p_09070 5edcbe7e09225eea351a6986f9fc7d04 79 Gene3D G3DSA:3.30.70.2400 1 74 1.0E-32 T 14-10-2018 TSH58p_26530 30117191a7a35450b1fa5865ca019bdd 114 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 108 1.3E-25 T 14-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like TSH58p_27200 d2a73e2e355844dbb0da0181d8b3fbab 102 Gene3D G3DSA:1.10.3990.20 23 101 3.6E-13 T 14-10-2018 IPR038268 Ribbon-helix-helix domain superfamily TSH58p_27200 d2a73e2e355844dbb0da0181d8b3fbab 102 Pfam PF13467 Ribbon-helix-helix domain 27 90 9.1E-21 T 14-10-2018 IPR027373 Ribbon-helix-helix domain TSH58p_11985 fdabf1bfce2dc9124c79150d2cdc596f 384 Pfam PF06089 L-asparaginase II 59 381 3.9E-117 T 14-10-2018 IPR010349 L-asparaginase II TSH58p_06355 0c06fdd6edea90714ccc1d6f919b4575 260 SMART SM00052 4 248 3.3E-35 T 14-10-2018 IPR001633 EAL domain TSH58p_06355 0c06fdd6edea90714ccc1d6f919b4575 260 SUPERFAMILY SSF141868 22 244 5.1E-59 T 14-10-2018 IPR035919 EAL domain superfamily TSH58p_06355 0c06fdd6edea90714ccc1d6f919b4575 260 Gene3D G3DSA:3.20.20.450 16 255 2.3E-67 T 14-10-2018 IPR035919 EAL domain superfamily TSH58p_06355 0c06fdd6edea90714ccc1d6f919b4575 260 Pfam PF00563 EAL domain 23 243 3.6E-50 T 14-10-2018 IPR001633 EAL domain TSH58p_25775 011a2f55902b3d1d7e7386882e817148 249 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 245 6.9E-25 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_25775 011a2f55902b3d1d7e7386882e817148 249 Gene3D G3DSA:1.10.3720.10 48 242 2.2E-23 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_25775 011a2f55902b3d1d7e7386882e817148 249 SUPERFAMILY SSF161098 49 230 5.36E-32 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_26800 2a716b18bd9de55a1035c8ad9a732c76 177 Gene3D G3DSA:1.10.10.10 95 172 6.1E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSH58p_26800 2a716b18bd9de55a1035c8ad9a732c76 177 SUPERFAMILY SSF46785 110 163 1.03E-6 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSH58p_23740 6871aed15c7f600d8e232c971f1337f1 255 Gene3D G3DSA:2.20.25.570 143 209 3.0E-28 T 14-10-2018 TSH58p_23740 6871aed15c7f600d8e232c971f1337f1 255 SUPERFAMILY SSF53335 21 251 1.8E-24 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSH58p_23740 6871aed15c7f600d8e232c971f1337f1 255 Gene3D G3DSA:3.40.50.150 38 235 3.0E-28 T 14-10-2018 TSH58p_23740 6871aed15c7f600d8e232c971f1337f1 255 Pfam PF13649 Methyltransferase domain 41 136 4.7E-10 T 14-10-2018 TSH58p_20045 1dded082810980e0ff537ba91fadc4b9 77 Pfam PF11747 Killing trait 12 75 4.4E-19 T 14-10-2018 IPR021070 Killing trait, RebB TSH58p_10675 a15af190bcb747e6b3cf2a678e4ca034 171 Pfam PF09361 Phasin protein 63 154 7.4E-8 T 14-10-2018 IPR018968 Phasin TSH58p_19165 eaf782f0645222387b3e9498152a3198 252 Pfam PF01311 Bacterial export proteins, family 1 14 241 4.1E-44 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 TSH58p_19165 eaf782f0645222387b3e9498152a3198 252 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 81 100 2.1E-15 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 TSH58p_19165 eaf782f0645222387b3e9498152a3198 252 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 203 222 2.1E-15 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 TSH58p_19165 eaf782f0645222387b3e9498152a3198 252 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 181 203 2.1E-15 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 TSH58p_19165 eaf782f0645222387b3e9498152a3198 252 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 21 42 2.1E-15 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 TSH58p_31815 ae74ecb1cf8f70049927cf6eb43ad9c1 249 Gene3D G3DSA:1.10.3720.10 52 246 2.9E-25 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_31815 ae74ecb1cf8f70049927cf6eb43ad9c1 249 SUPERFAMILY SSF161098 56 233 2.62E-26 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_31815 ae74ecb1cf8f70049927cf6eb43ad9c1 249 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 71 248 9.8E-26 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_03335 10c601f1d93fc7242aab77db1a78cf16 277 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 53 269 1.1E-35 T 14-10-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related TSH58p_17115 5d11e66020bc0c1acc71eb485480d021 137 Gene3D G3DSA:3.40.50.2300 13 137 1.6E-14 T 14-10-2018 TSH58p_17115 5d11e66020bc0c1acc71eb485480d021 137 SMART SM00448 16 129 6.0E-7 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_17115 5d11e66020bc0c1acc71eb485480d021 137 SUPERFAMILY SSF52172 16 135 1.32E-17 T 14-10-2018 IPR011006 CheY-like superfamily TSH58p_17115 5d11e66020bc0c1acc71eb485480d021 137 Pfam PF00072 Response regulator receiver domain 18 129 6.5E-8 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSH58p_21430 92648d00d7af2de9d1bc63f4cdce6ad3 179 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 41 170 1.3E-25 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ TSH58p_18550 92648d00d7af2de9d1bc63f4cdce6ad3 179 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 41 170 1.3E-25 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ TSH58p_11270 4ed5676b596b583debbf87e55cd014e5 305 Pfam PF01925 Sulfite exporter TauE/SafE 18 286 3.7E-47 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TSH58p_01875 b8aae9f6356a3274a267a159451df3df 379 Pfam PF06472 ABC transporter transmembrane region 2 11 301 5.4E-34 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TSH58p_01875 b8aae9f6356a3274a267a159451df3df 379 SUPERFAMILY SSF90123 32 348 3.53E-17 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSH58p_18770 53192273769b9ae545f4d0b6b4da8a23 287 Pfam PF09955 Predicted integral membrane protein (DUF2189) 95 221 2.1E-38 T 14-10-2018 IPR018692 Predicted integral membrane protein DUF2189 TSH58p_32170 0534cb72b0b98ebc6ab9c49eb5563103 320 Pfam PF01758 Sodium Bile acid symporter family 44 220 5.0E-14 T 14-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 TSH58p_32170 0534cb72b0b98ebc6ab9c49eb5563103 320 Gene3D G3DSA:1.20.1530.20 9 315 3.0E-24 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily TSH58p_10325 5de058bc5b338e3e9a6a66e53203ad79 163 SUPERFAMILY SSF53955 4 149 1.48E-48 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily TSH58p_10325 5de058bc5b338e3e9a6a66e53203ad79 163 Gene3D G3DSA:1.10.530.40 5 150 6.8E-51 T 14-10-2018 TSH58p_10325 5de058bc5b338e3e9a6a66e53203ad79 163 Pfam PF00959 Phage lysozyme 30 128 1.3E-17 T 14-10-2018 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 TSH58p_18085 79dd3da9ca170dacff908a5e7b506bbe 501 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 21 439 1.5E-152 T 14-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane TSH58p_31155 db8c8e333e9b80bc4bd6c1c81c5b36f7 97 Pfam PF08734 GYD domain 4 93 5.8E-32 T 14-10-2018 IPR014845 Protein GYD/TTHA1554 TSH58p_19690 0df620977e9be2d2e9641359aca245c6 517 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 21 437 4.0E-133 T 14-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane TSH58p_12425 e5e1f79e8b3959fcd2fc7c3774e15b86 168 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 33 164 8.8E-32 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ TSH58p_03315 08e116ec94bdfdc23b986e10a6418054 256 Pfam PF02754 Cysteine-rich domain 18 98 5.7E-11 T 14-10-2018 IPR004017 Cysteine-rich domain TSH58p_03315 08e116ec94bdfdc23b986e10a6418054 256 Pfam PF02754 Cysteine-rich domain 146 230 2.6E-16 T 14-10-2018 IPR004017 Cysteine-rich domain TSH58p_03640 efecc873d5cad6f1a322abd82cb6eec5 80 Gene3D G3DSA:1.10.3990.20 1 79 4.1E-19 T 14-10-2018 IPR038268 Ribbon-helix-helix domain superfamily TSH58p_03640 efecc873d5cad6f1a322abd82cb6eec5 80 Pfam PF13467 Ribbon-helix-helix domain 1 61 3.3E-23 T 14-10-2018 IPR027373 Ribbon-helix-helix domain TSH58p_32265 e2aa7d143da6bed6c6f2def13b599a37 439 Pfam PF01943 Polysaccharide biosynthesis protein 29 286 1.6E-15 T 14-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 TSH58p_20300 64a2d0f4131333d23e804785d83902f2 203 Pfam PF09849 Uncharacterized protein conserved in bacteria (DUF2076) 1 186 4.9E-50 T 14-10-2018 IPR018648 Protein of unknown function DUF2076 TSH58p_00710 f29a1d5d51aa96f71e404eb670dc7352 97 Pfam PF09928 Predicted small integral membrane protein (DUF2160) 10 97 8.9E-36 T 14-10-2018 IPR018678 Protein of unknown function DUF2160, transmembrane TSH58p_29280 c7073579263b2654d30b8989870a924a 105 Pfam PF01618 MotA/TolQ/ExbB proton channel family 4 93 1.6E-8 T 14-10-2018 IPR002898 MotA/TolQ/ExbB proton channel TSH58p_16345 0f47c2a7ff9719ea023d4c076df21054 338 Pfam PF00953 Glycosyl transferase family 4 80 233 1.2E-28 T 14-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 TSH58p_07555 280517e9423afbc13d4980a4224e7dad 63 Pfam PF00037 4Fe-4S binding domain 4 26 9.6E-8 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSH58p_07555 280517e9423afbc13d4980a4224e7dad 63 Gene3D G3DSA:3.30.70.20 2 63 1.1E-19 T 14-10-2018 TSH58p_07555 280517e9423afbc13d4980a4224e7dad 63 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 10 21 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSH58p_07555 280517e9423afbc13d4980a4224e7dad 63 SUPERFAMILY SSF54862 5 61 9.27E-14 T 14-10-2018 TSH58p_25980 39e4605d7c16e45567f00449e8d92e49 107 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 5 100 1.4E-18 T 14-10-2018 IPR008407 Branched-chain amino acid transport, AzlD TSH58p_10440 3bbe30998b01894207789d8e264ac9fa 248 Gene3D G3DSA:3.40.50.10310 1 247 2.1E-73 T 14-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 TSH58p_10440 3bbe30998b01894207789d8e264ac9fa 248 Pfam PF02633 Creatinine amidohydrolase 7 239 2.5E-59 T 14-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 TSH58p_10440 3bbe30998b01894207789d8e264ac9fa 248 SUPERFAMILY SSF102215 2 244 7.19E-70 T 14-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 TSH58p_23135 5427c133ecd3295506c671488c73c4c6 252 Pfam PF13761 Domain of unknown function (DUF4166) 15 175 3.9E-33 T 14-10-2018 IPR025311 Domain of unknown function DUF4166 TSH58p_19770 28e9d0a5f3b75fb3cc3c0535a9b4df72 353 Pfam PF03601 Conserved hypothetical protein 698 18 329 2.5E-65 T 14-10-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 TSH58p_25530 095fa8c1211a846d7f64e589b9938d60 178 Gene3D G3DSA:3.40.470.10 8 174 4.4E-55 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSH58p_25530 095fa8c1211a846d7f64e589b9938d60 178 SUPERFAMILY SSF52141 7 169 2.57E-37 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSH58p_25530 095fa8c1211a846d7f64e589b9938d60 178 Pfam PF03167 Uracil DNA glycosylase superfamily 11 164 1.2E-17 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSH58p_31915 fa726d69fc61fca0913de1ba4c558c1d 293 SUPERFAMILY SSF161098 89 274 2.35E-32 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_31915 fa726d69fc61fca0913de1ba4c558c1d 293 Gene3D G3DSA:1.10.3720.10 88 279 3.4E-24 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_31915 fa726d69fc61fca0913de1ba4c558c1d 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 255 1.2E-21 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_00425 15bd32ac44711dd75622840f04ea1248 357 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 332 4.1E-40 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_06795 0d51578e2201ab137c7fd2a077f790c7 334 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 31 318 7.4E-39 T 14-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD TSH58p_16140 7590035332dbd9e7a2bab2e9893ff2da 277 SUPERFAMILY SSF49842 154 274 4.04E-9 T 14-10-2018 IPR008983 Tumour necrosis factor-like domain superfamily GO:0005515 TSH58p_20710 50eee807f3259148f1d3f9f234171ae2 321 Gene3D G3DSA:1.20.81.30 147 255 8.1E-8 T 14-10-2018 TSH58p_20710 50eee807f3259148f1d3f9f234171ae2 321 Pfam PF00482 Type II secretion system (T2SS), protein F 154 273 4.2E-20 T 14-10-2018 IPR018076 Type II secretion system F domain TSH58p_09830 140109a25c429476807343317f48f4fa 309 Pfam PF03547 Membrane transport protein 164 302 3.5E-13 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 TSH58p_09830 140109a25c429476807343317f48f4fa 309 Pfam PF03547 Membrane transport protein 4 128 1.2E-11 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 TSH58p_22695 7550f5e85e2617917231531f5e0bdb54 340 Pfam PF03864 Phage major capsid protein E 4 338 1.4E-76 T 14-10-2018 IPR005564 Major capsid protein GpE TSH58p_22695 7550f5e85e2617917231531f5e0bdb54 340 Gene3D G3DSA:3.15.30.10 27 329 6.9E-104 T 14-10-2018 TSH58p_22695 7550f5e85e2617917231531f5e0bdb54 340 Gene3D G3DSA:3.30.1930.10 155 282 6.9E-104 T 14-10-2018 TSH58p_07475 e2445ff3cf4c2a5cfed8006f0a976955 245 PIRSF PIRSF000851 13 245 5.1E-85 T 14-10-2018 IPR026027 Phosphatidylcholine synthase Pcs KEGG: 00564+2.7.8.24|MetaCyc: PWY-6826 TSH58p_03535 b1672cddaf459530cba584bb10896fd5 326 Pfam PF05136 Phage portal protein, lambda family 6 178 3.0E-43 T 14-10-2018 IPR006429 Phage portal protein, lambda family GO:0005198|GO:0019068 TSH58p_01505 10c14d0fa0955ca28b04d38b99eaf395 382 Pfam PF03929 PepSY-associated TM region 13 357 3.5E-53 T 14-10-2018 IPR005625 PepSY-associated TM protein TSH58p_31775 92e1a764b2abff96e53fe27196a6cc4c 262 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 247 1.4E-8 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSH58p_31775 92e1a764b2abff96e53fe27196a6cc4c 262 Gene3D G3DSA:1.10.3720.10 1 259 4.9E-47 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_31775 92e1a764b2abff96e53fe27196a6cc4c 262 SUPERFAMILY SSF161098 2 249 1.5E-48 T 14-10-2018 IPR035906 MetI-like superfamily TSH58p_02565 8164c323bb06f8533bb1db89b31a50a8 116 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 4 107 1.4E-9 T 14-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family TSH58p_02565 8164c323bb06f8533bb1db89b31a50a8 116 Gene3D G3DSA:3.30.2310.20 1 112 2.1E-14 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily TSH58p_02725 1ca51adecee570feaaca815a45639248 312 Pfam PF00892 EamA-like transporter family 154 288 1.3E-18 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_02725 1ca51adecee570feaaca815a45639248 312 Pfam PF00892 EamA-like transporter family 15 141 9.4E-18 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSH58p_02725 1ca51adecee570feaaca815a45639248 312 SUPERFAMILY SSF103481 44 144 1.83E-15 T 14-10-2018 TSH58p_02725 1ca51adecee570feaaca815a45639248 312 SUPERFAMILY SSF103481 187 291 1.05E-14 T 14-10-2018 TSH58p_19325 4088ab9e974212fb2289065b510c72f4 93 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 6 78 4.1E-10 T 14-10-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 TSH58p_04150 36f8465dd911018391a47a958a377bd2 230 Pfam PF14196 L-2-amino-thiazoline-4-carboxylic acid hydrolase 129 219 7.5E-13 T 14-10-2018 IPR026002 L-2-amino-thiazoline-4-carboxylic acid hydrolase TSH58p_00785 867e9cde6cd20aba479365b80d2c580c 373 Pfam PF01145 SPFH domain / Band 7 family 53 247 1.3E-15 T 14-10-2018 IPR001107 Band 7 domain TSH58p_24870 808be1cc8ce5f981b5a0684a51f8d305 445 Pfam PF04932 O-Antigen ligase 194 333 2.4E-11 T 14-10-2018 IPR007016 O-antigen ligase-related TSH58p_14500 8e760a4f3d1c8a5ca45dcaa9e328d707 240 Pfam PF04172 LrgB-like family 23 236 2.4E-81 T 14-10-2018 IPR007300 CidB/LrgB family TSH58p_32250 07b4e5805fd952a1b54afa77b3004aed 748 Gene3D G3DSA:3.40.50.300 491 739 2.9E-17 T 14-10-2018 TSH58p_32250 07b4e5805fd952a1b54afa77b3004aed 748 SUPERFAMILY SSF52540 551 741 3.72E-8 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_06850 65b43f1a87de1fb84edb9d8f05a3808b 73 Pfam PF13770 Domain of unknown function (DUF4169) 2 55 1.3E-21 T 14-10-2018 IPR025227 Protein of unknown function DUF4169 TSH58p_26180 cc658ef466995374c0686f91cb870a25 108 Pfam PF11804 Protein of unknown function (DUF3325) 3 101 3.6E-32 T 14-10-2018 IPR021762 Protein of unknown function DUF3325 TSH58p_18610 1d03eab20ac9da571f822f4011290783 162 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 13 148 4.2E-17 T 14-10-2018 IPR009936 Protein of unknown function DUF1468 TSH58p_03155 e74f00b741553fc315f17d2bff7b975a 499 Pfam PF02652 L-lactate permease 79 262 9.9E-6 T 14-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 TSH58p_03155 e74f00b741553fc315f17d2bff7b975a 499 Pfam PF02652 L-lactate permease 322 478 4.0E-13 T 14-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 TSH58p_25965 a3b71523e8b5167d6bbbf84280c19509 218 Pfam PF03006 Haemolysin-III related 21 209 3.2E-23 T 14-10-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 TSH58p_19410 88c9e2bc6f3e37577c4be06e9d2c3e40 126 SUPERFAMILY SSF54427 3 125 4.59E-41 T 14-10-2018 IPR032710 NTF2-like domain superfamily TSH58p_19410 88c9e2bc6f3e37577c4be06e9d2c3e40 126 Gene3D G3DSA:3.10.450.50 1 126 2.6E-52 T 14-10-2018 TSH58p_19410 88c9e2bc6f3e37577c4be06e9d2c3e40 126 Pfam PF11533 Protein of unknown function (DUF3225) 4 125 2.7E-61 T 14-10-2018 IPR024507 Protein of unknown function DUF3225 TSH58p_03665 fccde3875316b0bca9d3d22794df9083 194 Pfam PF10688 Bacterial inner membrane protein 6 162 1.9E-23 T 14-10-2018 IPR019629 Uncharacterised protein family HI1736/YgjV TSH58p_21340 53695c6bd921ab78a15a5171e8d605c4 346 Pfam PF02653 Branched-chain amino acid transport system / permease component 46 311 3.4E-34 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_20085 70d068c64030689d5d4d9aa7574bf351 653 Pfam PF14252 Domain of unknown function (DUF4347) 30 182 6.6E-46 T 14-10-2018 IPR025592 Domain of unknown function DUF4347 TSH58p_24170 55ec242ef48b970dd4406dd791813c8e 373 Pfam PF03739 Predicted permease YjgP/YjgQ family 6 357 8.7E-66 T 14-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 TSH58p_24170 55ec242ef48b970dd4406dd791813c8e 373 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 4 357 4.8E-72 T 14-10-2018 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 TSH58p_03700 674404fe57843d51aec14ebf4538eb29 150 Pfam PF07173 Glycine-rich domain-containing protein-like 34 77 2.9E-6 T 14-10-2018 IPR009836 Glycine-rich domain-containing protein-like TSH58p_09235 63573fa6e1f7969757d07111ef7f6273 631 SUPERFAMILY SSF50969 237 492 8.11E-5 T 14-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like TSH58p_13780 e56f44bbdd53852a39881a584ebd0373 339 Pfam PF02653 Branched-chain amino acid transport system / permease component 41 322 1.8E-39 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_23790 39a7eb459e1690c02a84002aac9576ce 249 Pfam PF13701 Transposase DDE domain group 1 30 225 4.7E-67 T 14-10-2018 IPR025668 Transposase DDE domain TSH58p_27830 fcb9b06c09c2c64ed40b64898f56398d 408 SUPERFAMILY SSF50969 33 400 4.08E-9 T 14-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like TSH58p_18980 5dec514782bb6b17765ecc4c6c2e61d7 377 Pfam PF04577 Protein of unknown function (DUF563) 144 344 2.8E-48 T 14-10-2018 IPR007657 Glycosyltransferase 61 GO:0016757 TSH58p_23235 3dc7e602c486e68bef97888ed51d3a01 142 PIRSF PIRSF032025 1 142 9.2E-46 T 14-10-2018 IPR008320 Uncharacterised conserved protein UCP032025 TSH58p_23235 3dc7e602c486e68bef97888ed51d3a01 142 Pfam PF07370 Protein of unknown function (DUF1489) 5 142 1.3E-49 T 14-10-2018 IPR008320 Uncharacterised conserved protein UCP032025 TSH58p_04900 6b0fd2485eaf7077aa843d1e86a2fe4b 215 Pfam PF12118 SprA-related family 51 157 1.2E-32 T 14-10-2018 IPR021973 SprA-related family TSH58p_01180 b337250c61d2bbbc8ede7de4a4e58a85 433 SUPERFAMILY SSF53706 18 356 1.33E-13 T 14-10-2018 TSH58p_16310 9fe60b1a8ab58d68e26ababd7e0a16c9 381 Gene3D G3DSA:3.30.1150.10 235 380 6.2E-19 T 14-10-2018 TSH58p_16310 9fe60b1a8ab58d68e26ababd7e0a16c9 381 SUPERFAMILY SSF74653 280 378 7.85E-6 T 14-10-2018 TSH58p_11440 29b57082e409533c7852eed98674a377 184 Gene3D G3DSA:1.20.1260.100 22 171 1.8E-6 T 14-10-2018 IPR038330 TspO/MBR-related superfamily TSH58p_11440 29b57082e409533c7852eed98674a377 184 Pfam PF03073 TspO/MBR family 29 164 1.9E-11 T 14-10-2018 IPR004307 TspO/MBR-related protein GO:0016021 TSH58p_31205 3286b670b74bbd29397cbbef2aeb57e0 128 Pfam PF13610 DDE domain 43 126 1.4E-8 T 14-10-2018 IPR032874 DDE domain TSH58p_00010 99c151328b96783922935685fdc8f576 64 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 2 54 1.0E-9 T 14-10-2018 IPR009936 Protein of unknown function DUF1468 TSH58p_25535 a139d1907ce3546b1b3924498df6292f 238 Pfam PF06912 Protein of unknown function (DUF1275) 17 222 5.9E-33 T 14-10-2018 IPR010699 Protein of unknown function DUF1275 TSH58p_26175 6ba69ad30579dd7c710ae8f889da2c28 547 Pfam PF03929 PepSY-associated TM region 10 373 3.6E-63 T 14-10-2018 IPR005625 PepSY-associated TM protein TSH58p_24855 7b6e4a9a311ac7b9c4bd1c292c9717bb 493 Pfam PF13440 Polysaccharide biosynthesis protein 34 272 3.3E-9 T 14-10-2018 TSH58p_02165 0b620bcc6da7aaa86d6077da4b8011e5 351 PIRSF PIRSF016660 232 341 8.1E-19 T 14-10-2018 IPR008526 Inner membrane protein YedI TSH58p_02165 0b620bcc6da7aaa86d6077da4b8011e5 351 PIRSF PIRSF016660 1 223 4.7E-78 T 14-10-2018 IPR008526 Inner membrane protein YedI TSH58p_02165 0b620bcc6da7aaa86d6077da4b8011e5 351 Pfam PF05661 Protein of unknown function (DUF808) 3 330 1.0E-117 T 14-10-2018 IPR008526 Inner membrane protein YedI TSH58p_06330 6435c88576c3de2f56f37e0e6b168791 85 Pfam PF04226 Transglycosylase associated protein 33 79 2.9E-14 T 14-10-2018 IPR007341 Transglycosylase-associated protein GO:0016021 TSH58p_17985 43403f099ce4d97f3a7f8896c8ab5f5e 234 Pfam PF09361 Phasin protein 129 218 8.8E-7 T 14-10-2018 IPR018968 Phasin TSH58p_22955 934c48f4047a2fd809c056db7b02ea03 116 Pfam PF09723 Zinc ribbon domain 1 40 2.3E-11 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain TSH58p_22955 934c48f4047a2fd809c056db7b02ea03 116 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 46 5.7E-13 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain TSH58p_22955 934c48f4047a2fd809c056db7b02ea03 116 SMART SM00834 1 41 1.0E-9 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain TSH58p_29800 ca3cf4dfaf57c9f0fbdc371ab062dd04 484 Pfam PF11739 Dicarboxylate transport 271 469 7.5E-41 T 14-10-2018 IPR021730 Dicarboxylate transport TSH58p_09040 c5f6f8121839b9599bcea8b28e9b8b65 466 Pfam PF01566 Natural resistance-associated macrophage protein 66 420 4.8E-18 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 TSH58p_28735 52a97316d9566ca1f8b8f895aba9967d 249 Pfam PF01925 Sulfite exporter TauE/SafE 10 246 9.7E-29 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TSH58p_22340 0d2a5ecf3bf9d0ae7e56898ffc5931b4 680 SUPERFAMILY SSF56349 453 505 9.12E-5 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TSH58p_09660 896de0cbedce0a161a0ac1b4e9307e8e 219 Pfam PF09335 SNARE associated Golgi protein 51 172 8.7E-18 T 14-10-2018 IPR032816 SNARE associated Golgi protein TSH58p_08795 2dc2e969770b73f4152887dc83613d7f 49 Pfam PF01744 GLTT repeat (6 copies) 24 43 9.2E-7 T 14-10-2018 IPR008164 Repeat of unknown function XGLTT TSH58p_24525 4ca2431d1bc44250654be1ec3e29526c 68 Pfam PF07869 Protein of unknown function (DUF1656) 4 59 2.8E-23 T 14-10-2018 IPR012451 Protein of unknown function DUF1656 TSH58p_16580 d340fc59ab8de33a5cce79e3a1d7ed9e 389 Pfam PF10098 Uncharacterised protein conserved in bacteria (DUF2336) 91 351 4.5E-61 T 14-10-2018 IPR019285 Protein of unknown function DUF2336 TSH58p_09415 ceba2d83361977cf11f2f3ea7173336c 409 Pfam PF10098 Uncharacterised protein conserved in bacteria (DUF2336) 148 402 1.1E-53 T 14-10-2018 IPR019285 Protein of unknown function DUF2336 TSH58p_25195 414b7f9d29bebd07839a09847f57ed58 395 Pfam PF13480 Acetyltransferase (GNAT) domain 196 343 4.6E-26 T 14-10-2018 IPR038740 BioF2-like, acetyltransferase domain KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 TSH58p_25195 414b7f9d29bebd07839a09847f57ed58 395 SUPERFAMILY SSF55729 189 336 1.17E-17 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSH58p_04160 3083923a7bab9ade0fff56cac96a2e8f 188 Pfam PF09361 Phasin protein 80 176 1.2E-18 T 14-10-2018 IPR018968 Phasin TSH58p_21220 a350091fc30b4b0023acd0ec64646b5e 248 SUPERFAMILY SSF53300 38 203 1.33E-8 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TSH58p_05475 25d90035f04d047b7b87272899543f2c 483 SUPERFAMILY SSF52540 215 401 2.21E-5 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSH58p_22345 8c44f3e138aea90a0bf747ebcd3589ae 421 SUPERFAMILY SSF56349 103 292 4.12E-11 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TSH58p_22345 8c44f3e138aea90a0bf747ebcd3589ae 421 Gene3D G3DSA:1.10.443.10 92 304 1.5E-10 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TSH58p_06940 ce8e57aff7a5e2161ad434627b23d448 237 Pfam PF04654 Protein of unknown function, DUF599 11 218 1.8E-57 T 14-10-2018 IPR006747 Protein of unknown function DUF599 TSH58p_22485 ff4b0b5b25eb8be208db0a4a7f63072e 271 Pfam PF02616 Segregation and condensation protein ScpA 42 123 2.6E-9 T 14-10-2018 IPR003768 Segregation and condensation protein A TSH58p_15415 f7f0d39736aea0120e4839496d8baa9b 173 Pfam PF03748 Flagellar basal body-associated protein FliL 76 173 8.8E-18 T 14-10-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 TSH58p_13730 9333d39281ef95c3251fa5c27eebc890 247 Pfam PF01925 Sulfite exporter TauE/SafE 7 241 2.8E-40 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TSH58p_18615 4b7ccf1e61853e7c1e54f9b4fc6b5c48 514 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 438 1.5E-149 T 14-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane TSH58p_01585 f0a432c020304c0ae21419465b4c4b1c 404 Pfam PF03929 PepSY-associated TM region 8 387 2.6E-53 T 14-10-2018 IPR005625 PepSY-associated TM protein TSH58p_19445 23589bfc178081215fee6c400f0cb0dc 345 Pfam PF02653 Branched-chain amino acid transport system / permease component 25 310 3.8E-45 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_12555 5ed3dbf326aa4d94c0a764ca0b64abb4 100 Pfam PF04341 Protein of unknown function, DUF485 10 96 2.8E-37 T 14-10-2018 IPR007436 Protein of unknown function DUF485 TSH58p_28855 52f41df74b13387d03948a5e4425b102 217 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 138 7.0E-34 T 14-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase TSH58p_13600 5cbeec6777309713379c7bd0caed0bef 52 Pfam PF08085 Entericidin EcnA/B family 25 44 1.9E-10 T 14-10-2018 IPR012556 Entericidin A/B GO:0009636|GO:0016020 TSH58p_24460 a3baf2f9f27066fb346df882540bbbc2 196 Pfam PF03458 UPF0126 domain 1 74 1.0E-19 T 14-10-2018 IPR005115 Uncharacterised domain UPF0126 TSH58p_24460 a3baf2f9f27066fb346df882540bbbc2 196 Pfam PF03458 UPF0126 domain 86 157 3.0E-19 T 14-10-2018 IPR005115 Uncharacterised domain UPF0126 TSH58p_03540 66c051d4c0ff8b75ac9ba8da314bd946 692 Pfam PF04586 Caudovirus prohead serine protease 105 166 1.6E-5 T 14-10-2018 IPR006433 Prohead protease TSH58p_03480 36ce3685a2e82b0f796802d2584bc577 300 Pfam PF06791 Prophage tail length tape measure protein 167 229 6.7E-10 T 14-10-2018 IPR009628 Bacteriophage lambda, GpH, tail tape measure, N-terminal TSH58p_09825 c2dc2c07991750c48908e1636f03cd2a 225 SUPERFAMILY SSF89562 24 185 3.01E-42 T 14-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily TSH58p_09825 c2dc2c07991750c48908e1636f03cd2a 225 Pfam PF03737 Aldolase/RraA 30 174 2.4E-35 T 14-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein TSH58p_09825 c2dc2c07991750c48908e1636f03cd2a 225 Gene3D G3DSA:3.50.30.100 2 196 6.9E-51 T 14-10-2018 TSH58p_02900 b30574cd7881ddcc2e776810d04ddb47 450 SMART SM00749 302 365 5.3E-8 T 14-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria TSH58p_02900 b30574cd7881ddcc2e776810d04ddb47 450 Pfam PF04972 BON domain 297 365 3.7E-20 T 14-10-2018 IPR007055 BON domain TSH58p_08840 dc22e6a2d6f7dfdaf307f4b4ae3d289f 477 Pfam PF01757 Acyltransferase family 85 435 2.6E-28 T 14-10-2018 IPR002656 Acyltransferase 3 GO:0016747 TSH58p_18155 1b5c77d3ceffaf5019a6283ff1042dec 839 Gene3D G3DSA:3.90.550.10 1 220 6.0E-8 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_18155 1b5c77d3ceffaf5019a6283ff1042dec 839 SUPERFAMILY SSF53448 2 222 1.04E-8 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSH58p_04140 a89db1c73c0fa950969d4d7a09a37bf6 295 Pfam PF02653 Branched-chain amino acid transport system / permease component 17 283 1.8E-39 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_23625 45a6b4734e176eb057f63517d0d12a63 295 Pfam PF02653 Branched-chain amino acid transport system / permease component 17 283 2.7E-38 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_28430 2576ce62e4de1a23a9c38e6650e2658e 296 Pfam PF08904 Domain of unknown function (DUF1849) 54 292 3.4E-85 T 14-10-2018 IPR015000 Protein of unknown function DUF1849 TSH58p_30035 69170fd2db34d89fac8d92223b1b0734 92 Pfam PF14076 Domain of unknown function (DUF4258) 6 62 2.0E-8 T 14-10-2018 IPR025354 Protein of unknown function DUF4258 TSH58p_03425 de4b8b35403b12a01f6dc998b2ef6c69 165 Pfam PF05876 Phage terminase large subunit (GpA) 36 159 4.6E-13 T 14-10-2018 IPR008866 Bacteriophage lambda, GpA TSH58p_17720 caad584bacb387840a78d4f56d0a5c78 614 Pfam PF04586 Caudovirus prohead serine protease 90 173 3.4E-6 T 14-10-2018 IPR006433 Prohead protease TSH58p_17720 caad584bacb387840a78d4f56d0a5c78 614 Pfam PF10124 Mu-like prophage major head subunit gpT 474 543 1.5E-4 T 14-10-2018 IPR018774 Bacteriophage Mu, GpT TSH58p_25720 d1380974238067d09c51cd7048e93418 199 Pfam PF11748 Protein of unknown function (DUF3306) 12 116 1.3E-24 T 14-10-2018 IPR021735 Protein of unknown function DUF3306 TSH58p_29395 81be94229ca0b971565f84f15f534f70 97 Pfam PF11272 Protein of unknown function (DUF3072) 41 95 1.1E-31 T 14-10-2018 IPR021425 Protein of unknown function DUF3072 TSH58p_17905 127fc82e0228e0ad1c8f60f1c069659b 312 Pfam PF04796 Plasmid encoded RepA protein 94 250 9.1E-76 T 14-10-2018 IPR006881 Plasmid encoded RepA protein TSH58p_24675 71daa4a62ccc7e47188ab08e8b2bd138 414 TIGRFAM TIGR04474 tcm_partner: three-Cys-motif partner protein 16 288 1.1E-60 T 14-10-2018 IPR031009 Three-Cys-motif partner protein TSH58p_03980 7fe7b013c49fd92ffa9e3779009f4632 228 Pfam PF02674 Colicin V production protein 10 151 3.3E-29 T 14-10-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 TSH58p_21385 d927adbe6686921ffa2a9b8cba79c145 403 Pfam PF02653 Branched-chain amino acid transport system / permease component 54 393 8.3E-49 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_19615 a2b664c185d42250b2e7671221de113c 174 Pfam PF14196 L-2-amino-thiazoline-4-carboxylic acid hydrolase 19 162 1.1E-37 T 14-10-2018 IPR026002 L-2-amino-thiazoline-4-carboxylic acid hydrolase TSH58p_27055 493f952dffba72156ceb8c963d06660c 132 Pfam PF07681 DoxX 13 91 1.9E-12 T 14-10-2018 IPR032808 DoxX family TSH58p_01500 fe5fdb2c6d2795572a2af681a7d0e6ac 152 PIRSF PIRSF029505 1 149 3.3E-38 T 14-10-2018 IPR016922 Uncharacterised conserved protein UCP029505 TSH58p_07515 d1306a8fb2ae14159f39302a6d287d16 377 Pfam PF12698 ABC-2 family transporter protein 26 369 3.4E-51 T 14-10-2018 TSH58p_27820 3ca65f86527ac42d9f384e56258ebbba 152 Pfam PF11911 Protein of unknown function (DUF3429) 13 147 1.8E-34 T 14-10-2018 IPR021836 Protein of unknown function DUF3429 TSH58p_30445 d4f52b04ab48d8d78090304ce2a2df76 291 Pfam PF02653 Branched-chain amino acid transport system / permease component 14 259 1.2E-27 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_27140 47abc602839615e5695265244cee7c4b 190 Pfam PF05433 Glycine zipper 2TM domain 144 184 5.1E-7 T 14-10-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 TSH58p_15055 e918ef7f6e7f11d3a3d448c4e0f2220b 202 Pfam PF13546 DDE superfamily endonuclease 24 201 1.3E-41 T 14-10-2018 IPR038721 Transposase IS701-like, DDE domain TSH58p_17300 b0f8a8e6f70bd7b7e89d529b79d77973 183 Pfam PF03981 Ubiquinol-cytochrome C chaperone 34 174 3.1E-36 T 14-10-2018 IPR021150 Ubiquinol-cytochrome c chaperone/UPF0174 TSH58p_09365 34ba4846ffe139b6262e4aa3152a7869 315 Pfam PF03547 Membrane transport protein 4 143 3.3E-11 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 TSH58p_09365 34ba4846ffe139b6262e4aa3152a7869 315 Pfam PF03547 Membrane transport protein 161 307 3.5E-17 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 TSH58p_16210 647f71eadae64ff914bd03cf5e1e3582 268 Pfam PF01925 Sulfite exporter TauE/SafE 12 247 8.5E-45 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TSH58p_19080 40410d4c235fb98fd83f68953bc9ea9b 179 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 41 170 2.6E-25 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ TSH58p_10060 47793149893709ff4f100b3baf7f17a3 340 Pfam PF12224 Putative amidoligase enzyme 18 299 1.5E-54 T 14-10-2018 IPR022025 Putative amidoligase enzyme TSH58p_27275 1497219d6926c0ef00908b796827f73e 141 Pfam PF03994 Domain of Unknown Function (DUF350) 24 73 2.1E-9 T 14-10-2018 IPR007140 Protein of unknown function DUF350 TSH58p_27275 1497219d6926c0ef00908b796827f73e 141 Pfam PF03994 Domain of Unknown Function (DUF350) 87 139 9.3E-11 T 14-10-2018 IPR007140 Protein of unknown function DUF350 TSH58p_32310 becf999253563bbd33054cfded3bee52 223 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 12 213 3.7E-62 T 14-10-2018 IPR022301 Integral membrane protein YjbE TSH58p_32310 becf999253563bbd33054cfded3bee52 223 Pfam PF03741 Integral membrane protein TerC family 15 213 5.3E-42 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 TSH58p_15535 fdad8068ccfb1cdf03c1fe75a26acfd7 134 Pfam PF06127 Protein of unknown function (DUF962) 6 94 2.7E-25 T 14-10-2018 IPR009305 Protein of unknown function DUF962 TSH58p_22940 783caaf736413591a35b467f3905f634 290 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 278 1.4E-32 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_24185 462d5e872c5be742b786b46176c9d3ac 329 Pfam PF02653 Branched-chain amino acid transport system / permease component 27 304 1.5E-36 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_06655 b89faafce62c3724f2dbc3fd100f0cee 140 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 54 137 9.4E-37 T 14-10-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 TSH58p_32525 3f813b12662d07ed383bedabf6d20ecb 289 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 276 4.7E-34 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_22540 e631c6cc11ff09febdcfd7cf2d62d217 119 Pfam PF04383 KilA-N domain 13 74 3.0E-6 T 14-10-2018 IPR018004 KilA, N-terminal/APSES-type HTH, DNA-binding TSH58p_30115 7abf68713e2f161c950e25e679f94a5c 310 Pfam PF04796 Plasmid encoded RepA protein 92 248 2.7E-37 T 14-10-2018 IPR006881 Plasmid encoded RepA protein TSH58p_08195 f6370ad13ce73ac1b3157ca063b6ff49 401 SUPERFAMILY SSF50630 30 395 6.57E-5 T 14-10-2018 IPR021109 Aspartic peptidase domain superfamily TSH58p_25420 cfae7d1710bc1f033c1d1165517f028e 296 Pfam PF13546 DDE superfamily endonuclease 24 169 5.7E-30 T 14-10-2018 IPR038721 Transposase IS701-like, DDE domain TSH58p_08340 f2c2910f14dba1e209e54772e47a7e6a 132 SUPERFAMILY SSF54427 9 125 5.56E-14 T 14-10-2018 IPR032710 NTF2-like domain superfamily TSH58p_08340 f2c2910f14dba1e209e54772e47a7e6a 132 Gene3D G3DSA:3.10.450.50 3 126 4.9E-9 T 14-10-2018 TSH58p_30060 0076748ff5d22abf3308903bc5e311d4 293 Pfam PF12952 Domain of unknown function (DUF3841) 90 215 3.5E-15 T 14-10-2018 IPR024211 Protein of unknown function DUF3841 TSH58p_23545 b3c7eaf4d79cc17f758c2fa5751db413 230 Pfam PF09929 Putative PD-(D/E)XK phosphodiesterase (DUF2161) 110 218 2.6E-39 T 14-10-2018 IPR018679 Putative PD-(D/E)XK phosphodiesterase (DUF2161) TSH58p_04450 6c878ca5c15a399ba95050afedb83ef2 278 Pfam PF11185 Protein of unknown function (DUF2971) 129 202 2.9E-9 T 14-10-2018 IPR021352 Protein of unknown function DUF2971 TSH58p_17545 19bc34d7e203378c6016dd8605ca1c55 338 Pfam PF07120 Protein of unknown function (DUF1376) 37 109 3.7E-7 T 14-10-2018 IPR010781 Protein of unknown function DUF1376 TSH58p_29235 06550905edfe2dafcd39a012d5405460 141 Pfam PF07378 Flagellar protein FlbT 3 119 4.8E-34 T 14-10-2018 IPR009967 Flagellum biosynthesis repressor FlbT GO:0006402|GO:0048027|GO:1902209 TSH58p_12670 89a5177d82c0f1dae82e4f51d28e160f 126 Pfam PF04138 GtrA-like protein 2 117 6.3E-28 T 14-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 TSH58p_00885 f19573ecfa4d05a4a35a99f8160ee2bc 126 Pfam PF16998 17 kDa outer membrane surface antigen 46 124 6.6E-7 T 14-10-2018 IPR032635 Surface antigen domain TSH58p_05185 913a0f9a8d1e2ef7308c419b8267077a 144 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 58 141 1.0E-36 T 14-10-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 TSH58p_31050 44e411bf6fd2493aae6687de33b55b18 71 Pfam PF07869 Protein of unknown function (DUF1656) 4 59 4.3E-17 T 14-10-2018 IPR012451 Protein of unknown function DUF1656 TSH58p_20565 071e687f828958badb06d910a669cab2 349 Pfam PF02653 Branched-chain amino acid transport system / permease component 59 335 3.1E-36 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSH58p_28740 38fbf64909cd3439a7637f368bf112e2 134 Gene3D G3DSA:1.20.1270.360 18 129 4.8E-30 T 14-10-2018 TSH58p_10690 4b6cf9cff679eaeff078a42e829ab064 60 SUPERFAMILY SSF47598 2 49 2.85E-6 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TSH58p_25350 b048936c396bb1dad10032b8e3263c7b 211 Pfam PF08747 Domain of unknown function (DUF1788) 74 206 1.7E-20 T 14-10-2018 IPR014858 Protein of unknown function DUF1788 TSH58p_22200 2cd3508158eca2cdb8f63397fc7afcfe 67 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 1 42 7.1E-17 T 14-10-2018 IPR019239 Bacterial antitoxin of type II TA system, VapB TSH58p_16435 2fd519ba7f2c6b6c950fdb895b92c50a 132 Pfam PF09345 Domain of unknown function (DUF1987) 7 125 8.8E-43 T 14-10-2018 IPR018530 Domain of unknown function DUF1987 TSH58p_22085 c0c28396e50cf9a74193bccf58bb9d25 534 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 122 257 1.0E-7 T 14-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like TSH58p_19465 9b66808c2d27801c41e07bf5af945fdd 278 Pfam PF01925 Sulfite exporter TauE/SafE 19 272 6.9E-48 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TSH58p_06025 1abaa0b265d0a83c0c4b35cb8bcfaa85 108 Pfam PF11127 Protein of unknown function (DUF2892) 19 74 9.7E-11 T 14-10-2018 IPR021309 Protein of unknown function DUF2892 TSH58p_19720 b97e5a6538476e8d9822107f6cdd1050 321 Pfam PF04976 DMSO reductase anchor subunit (DmsC) 1 317 2.6E-50 T 14-10-2018 IPR007059 DMSO reductase anchor subunit (DmsC) GO:0016021|GO:0019645 TSH58p_00740 85f14fa96455b3f02ca2d69dc8d23093 201 Pfam PF09335 SNARE associated Golgi protein 30 161 4.7E-22 T 14-10-2018 IPR032816 SNARE associated Golgi protein TSH58p_31595 de89bce5bde22f76a9fd3d482e1ad98f 373 Pfam PF12698 ABC-2 family transporter protein 23 362 6.8E-30 T 14-10-2018 TSH58p_12255 ce211bee6c300a22cf05a836e6630b55 186 Pfam PF07813 LTXXQ motif family protein 55 147 1.0E-20 T 14-10-2018 IPR012899 LTXXQ motif family protein GO:0042597 TSH58p_13810 7632a6ed4f881f077bc7fc4e778aa717 212 Pfam PF04315 Elongation factor P hydroxylase 91 118 3.8E-5 T 14-10-2018 IPR007411 Elongation factor P hydroxylase