locus-tag	class	description
GKQ51_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GKQ51_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GKQ51_00065	COG1686	Belongs to the peptidase S11 family
GKQ51_00085	COG0252	asparaginase activity
GKQ51_00110	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GKQ51_00120	COG3712	iron ion homeostasis
GKQ51_00160	COG0659	secondary active sulfate transmembrane transporter activity
GKQ51_00175	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GKQ51_00180	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
GKQ51_00205	COG1612	heme a metabolic process
GKQ51_00210	COG0109	protoheme IX farnesyltransferase activity
GKQ51_00230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GKQ51_00235	COG1121	(ABC) transporter
GKQ51_00240	COG0735	belongs to the Fur family
GKQ51_00245	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GKQ51_00250	COG1305	Transglutaminase-like
GKQ51_00260	COG1372	Participates in initiation and elongation during chromosome replication
GKQ51_00260	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKQ51_00310	COG5499	transcription regulator containing HTH domain
GKQ51_00315	COG4680	protein conserved in bacteria
GKQ51_00320	COG2945	thiolester hydrolase activity
GKQ51_00320	COG0596	Alpha beta hydrolase
GKQ51_00345	COG0826	peptidase U32
GKQ51_00355	COG0210	DNA helicase
GKQ51_00370	COG3706	GGDEF domain
GKQ51_00380	COG0700	Nucleoside recognition
GKQ51_00385	COG0655	NAD(P)H dehydrogenase (quinone) activity
GKQ51_00425	COG1285	pathogenesis
GKQ51_00435	COG2132	Multicopper oxidase
GKQ51_00445	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GKQ51_00450	COG0408	coproporphyrinogen oxidase activity
GKQ51_00460	COG0009	L-threonylcarbamoyladenylate synthase
GKQ51_00465	COG0758	DNA mediated transformation
GKQ51_00470	COG1652	LysM domain
GKQ51_00480	COG0242	peptide deformylase activity
GKQ51_00490	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GKQ51_00495	COG0569	domain protein
GKQ51_00505	COG2818	Glycosylase
GKQ51_00515	COG0751	glycine-tRNA ligase activity
GKQ51_00520	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GKQ51_00535	COG2837	iron assimilation
GKQ51_00545	COG2814	Major facilitator Superfamily
GKQ51_00550	COG0318	PFAM AMP-dependent synthetase and ligase
GKQ51_00550	COG0204	Acyl-transferase
GKQ51_00635	COG3411	Ferredoxin
GKQ51_00745	COG0523	cobalamin synthesis protein
GKQ51_00760	COG1607	acyl-coa hydrolase
GKQ51_00780	COG1764	response to oxidative stress
GKQ51_00850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GKQ51_00900	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GKQ51_00905	COG3023	N-Acetylmuramoyl-L-alanine amidase
GKQ51_00925	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GKQ51_00930	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GKQ51_00945	COG0583	DNA-binding transcription factor activity
GKQ51_00950	COG0439	Biotin carboxylase
GKQ51_00955	COG0511	ligase activity, forming carbon-carbon bonds
GKQ51_00955	COG5016	pyruvate
GKQ51_00960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GKQ51_00965	COG3360	Dodecin
GKQ51_00970	COG1132	(ABC) transporter
GKQ51_00980	COG0133	tryptophan synthase activity
GKQ51_00985	COG0159	tryptophan synthase activity
GKQ51_01020	COG0484	heat shock protein binding
GKQ51_01025	COG0789	Transcriptional regulator
GKQ51_01030	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GKQ51_01030	COG0116	Belongs to the methyltransferase superfamily
GKQ51_01070	COG3237	CsbD-like
GKQ51_01080	COG2982	Protein involved in outer membrane biogenesis
GKQ51_01090	COG0778	Nitroreductase
GKQ51_01095	COG1136	(ABC) transporter
GKQ51_01095	COG0577	efflux transmembrane transporter activity
GKQ51_01120	COG0366	Alpha amylase catalytic
GKQ51_01145	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GKQ51_01160	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GKQ51_01165	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GKQ51_01210	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GKQ51_01215	COG0346	lactoylglutathione lyase activity
GKQ51_01290	COG0149	triose-phosphate isomerase activity
GKQ51_01315	COG2132	Multicopper oxidase
GKQ51_01320	COG2132	Multicopper oxidase
GKQ51_01330	COG0861	Integral membrane protein TerC family
GKQ51_01335	COG2851	Citrate transporter
GKQ51_01345	COG2828	Protein conserved in bacteria
GKQ51_01350	COG0583	DNA-binding transcription factor activity
GKQ51_01355	COG1053	succinate dehydrogenase
GKQ51_01365	COG0583	DNA-binding transcription factor activity
GKQ51_01370	COG2828	Protein conserved in bacteria
GKQ51_01375	COG2851	Citrate transporter
GKQ51_01380	COG0861	Integral membrane protein TerC family
GKQ51_01405	COG0318	PFAM AMP-dependent synthetase and ligase
GKQ51_01410	COG0789	Transcriptional regulator
GKQ51_01415	COG1960	acyl-CoA dehydrogenase activity
GKQ51_01420	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GKQ51_01445	COG3180	Ammonia monooxygenase
GKQ51_01485	COG0528	UMP kinase activity
GKQ51_01490	COG0528	UMP kinase activity
GKQ51_01515	COG1136	(ABC) transporter
GKQ51_01545	COG1012	belongs to the aldehyde dehydrogenase family
GKQ51_01570	COG0596	Alpha beta hydrolase
GKQ51_01575	COG0322	excinuclease ABC activity
GKQ51_01640	COG0667	Aldo Keto reductase
GKQ51_01660	COG3909	cytochrome
GKQ51_01700	COG0640	Transcriptional regulator
GKQ51_01715	COG0174	glutamine synthetase
GKQ51_01720	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GKQ51_01725	COG0174	glutamine synthetase
GKQ51_01765	COG3842	ATPase activity
GKQ51_01770	COG1176	ABC-type spermidine putrescine transport system, permease component I
GKQ51_01775	COG1177	transmembrane transport
GKQ51_01780	COG0625	glutathione transferase activity
GKQ51_01795	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GKQ51_01815	COG0676	glucose-6-phosphate 1-epimerase activity
GKQ51_01820	COG1607	acyl-coa hydrolase
GKQ51_01835	COG0573	inorganic phosphate transmembrane transporter activity
GKQ51_01850	COG0739	heme binding
GKQ51_01855	COG1253	flavin adenine dinucleotide binding
GKQ51_01870	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GKQ51_01895	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GKQ51_01900	COG0583	DNA-binding transcription factor activity
GKQ51_01935	COG1683	Conserved Protein
GKQ51_01940	COG3180	Ammonia monooxygenase
GKQ51_01950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GKQ51_01955	COG0277	FAD linked oxidase domain protein
GKQ51_01960	COG0179	Fumarylacetoacetate (FAA) hydrolase
GKQ51_01965	COG3204	pilus organization
GKQ51_01975	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GKQ51_01995	COG0494	nUDIX hydrolase
GKQ51_02000	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
GKQ51_02015	COG0069	glutamate synthase activity
GKQ51_02020	COG0730	response to heat
GKQ51_02025	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GKQ51_02030	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GKQ51_02035	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GKQ51_02045	COG0584	glycerophosphoryl diester phosphodiesterase
GKQ51_02070	COG0675	Transposase, IS605 OrfB family
GKQ51_02080	COG2205	protein histidine kinase activity
GKQ51_02105	COG3436	PFAM IS66 Orf2 family protein
GKQ51_02110	COG4372	Transposase
GKQ51_02140	COG5642	Protein of unknown function (DUF2384)
GKQ51_02145	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GKQ51_02150	COG0842	Transport permease protein
GKQ51_02155	COG1131	(ABC) transporter
GKQ51_02160	COG0840	transmembrane signaling receptor activity
GKQ51_02165	COG0693	protein deglycase activity
GKQ51_02170	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GKQ51_02205	COG0247	lactate metabolic process
GKQ51_02215	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GKQ51_02255	COG0543	2 iron, 2 sulfur cluster binding
GKQ51_02260	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GKQ51_02275	COG2194	sulfuric ester hydrolase activity
GKQ51_02300	COG1151	hydroxylamine reductase activity
GKQ51_02320	COG2814	Major facilitator Superfamily
GKQ51_02330	COG0110	maltose O-acetyltransferase activity
GKQ51_02360	COG4772	TonB-dependent receptor
GKQ51_02365	COG3712	iron ion homeostasis
GKQ51_02370	COG1595	DNA-templated transcription, initiation
GKQ51_02385	COG1546	Belongs to the CinA family
GKQ51_02400	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GKQ51_02425	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GKQ51_02430	COG0358	DNA primase activity
GKQ51_02440	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GKQ51_02445	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GKQ51_02450	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GKQ51_02480	COG0617	tRNA 3'-terminal CCA addition
GKQ51_02485	COG2719	SpoVR family
GKQ51_02490	COG2718	Belongs to the UPF0229 family
GKQ51_02495	COG2766	serine protein kinase
GKQ51_02500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GKQ51_02505	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GKQ51_02510	COG2967	ApaG domain
GKQ51_02515	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GKQ51_02520	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GKQ51_02530	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GKQ51_02540	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GKQ51_02545	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GKQ51_02555	COG0477	Major facilitator Superfamily
GKQ51_02560	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GKQ51_02565	COG1028	Short-chain dehydrogenase reductase Sdr
GKQ51_02570	COG0583	DNA-binding transcription factor activity
GKQ51_02575	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GKQ51_02580	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GKQ51_02590	COG0583	DNA-binding transcription factor activity
GKQ51_02660	COG0583	DNA-binding transcription factor activity
GKQ51_02695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GKQ51_02730	COG2249	NAD(P)H dehydrogenase (quinone) activity
GKQ51_02745	COG1335	isochorismatase
GKQ51_02765	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GKQ51_02770	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GKQ51_02775	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GKQ51_02780	COG0508	dehydrogenase complex catalyzes the overall conversion of
GKQ51_02780	COG0022	dehydrogenase e1 component
GKQ51_02810	COG0512	Glutamine amidotransferase of anthranilate synthase
GKQ51_02815	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GKQ51_02820	COG0134	indole-3-glycerol-phosphate synthase activity
GKQ51_02830	COG1765	OsmC-like protein
GKQ51_02835	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GKQ51_02840	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
GKQ51_02845	COG0537	adenosine 5'-monophosphoramidase activity
GKQ51_02850	COG1981	membrane
GKQ51_02855	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GKQ51_02860	COG0316	Belongs to the HesB IscA family
GKQ51_02870	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GKQ51_02875	COG0739	heme binding
GKQ51_02900	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GKQ51_02960	COG0330	HflC and HflK could
GKQ51_02965	COG0686	Belongs to the AlaDH PNT family
GKQ51_02970	COG1309	transcriptional regulator
GKQ51_02980	COG0625	glutathione transferase activity
GKQ51_02990	COG2814	Major facilitator Superfamily
GKQ51_03005	COG0204	Acyl-transferase
GKQ51_03015	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GKQ51_03020	COG2176	DNA-directed DNA polymerase activity
GKQ51_03040	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GKQ51_03050	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GKQ51_03055	COG1040	competence protein
GKQ51_03065	COG0156	8-amino-7-oxononanoate synthase activity
GKQ51_03070	COG0596	Alpha beta hydrolase
GKQ51_03080	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GKQ51_03085	COG0204	Acyl-transferase
GKQ51_03090	COG4589	Belongs to the CDS family
GKQ51_03110	COG0716	FMN binding
GKQ51_03120	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GKQ51_03155	COG3237	CsbD-like
GKQ51_03160	COG1960	acyl-CoA dehydrogenase activity
GKQ51_03175	COG3852	Histidine kinase
GKQ51_03195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GKQ51_03195	COG0301	tRNA thio-modification
GKQ51_03200	COG1217	gtp-binding protein TYPA
GKQ51_03215	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GKQ51_03275	COG0058	SHG alpha-glucan phosphorylase activity
GKQ51_03280	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GKQ51_03305	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GKQ51_03320	COG1490	D-aminoacyl-tRNA deacylase activity
GKQ51_03365	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GKQ51_03370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GKQ51_03385	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GKQ51_03395	COG2226	methyltransferase
GKQ51_03405	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GKQ51_03410	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GKQ51_03420	COG0018	arginyl-trna synthetase
GKQ51_03425	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GKQ51_03430	COG0254	rRNA binding
GKQ51_03445	COG0281	malic enzyme
GKQ51_03480	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GKQ51_03485	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GKQ51_03495	COG0070	glutamate synthase
GKQ51_03495	COG0067	glutamate synthase
GKQ51_03495	COG0069	glutamate synthase activity
GKQ51_03500	COG0493	'glutamate synthase
GKQ51_03510	COG2814	Major facilitator Superfamily
GKQ51_03515	COG0583	DNA-binding transcription factor activity
GKQ51_03520	COG1192	Involved in chromosome partitioning
GKQ51_03530	COG3118	belongs to the thioredoxin family
GKQ51_03535	COG0730	response to heat
GKQ51_03545	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GKQ51_03550	COG3264	Mechanosensitive ion channel
GKQ51_03550	COG1196	nuclear chromosome segregation
GKQ51_03555	COG3263	regulation of cellular component size
GKQ51_03560	COG1942	4-Oxalocrotonate Tautomerase
GKQ51_03570	COG0583	DNA-binding transcription factor activity
GKQ51_03575	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GKQ51_03580	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GKQ51_03605	COG0859	PFAM glycosyl transferase family 9
GKQ51_03610	COG0859	PFAM glycosyl transferase family 9
GKQ51_03615	COG0438	transferase activity, transferring glycosyl groups
GKQ51_03635	COG2192	nodulation
GKQ51_03640	COG0438	transferase activity, transferring glycosyl groups
GKQ51_03655	COG1442	glycosyl transferase family 8
GKQ51_03660	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GKQ51_03675	COG1132	(ABC) transporter
GKQ51_03695	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GKQ51_03695	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GKQ51_03700	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GKQ51_03700	COG2755	lipolytic protein G-D-S-L family
GKQ51_03710	COG0667	Aldo Keto reductase
GKQ51_03720	COG1519	Transferase
GKQ51_03725	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GKQ51_03735	COG0494	nUDIX hydrolase
GKQ51_03755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GKQ51_03780	COG1215	transferase activity, transferring glycosyl groups
GKQ51_03795	COG3660	Nucleoside-diphosphate-sugar epimerase
GKQ51_03820	COG1183	phosphatidylcholine synthase activity
GKQ51_03830	COG0795	lipopolysaccharide-transporting ATPase activity
GKQ51_03845	COG0456	acetyltransferase
GKQ51_03850	COG0318	PFAM AMP-dependent synthetase and ligase
GKQ51_03860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKQ51_03865	COG0156	8-amino-7-oxononanoate synthase activity
GKQ51_03920	COG1215	transferase activity, transferring glycosyl groups
GKQ51_03970	COG2823	Periplasmic or secreted lipoprotein
GKQ51_03975	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GKQ51_03980	COG3150	esterase
GKQ51_04005	COG1741	Belongs to the pirin family
GKQ51_04015	COG2205	protein histidine kinase activity
GKQ51_04015	COG2202	Pas domain
GKQ51_04030	COG1139	Iron-sulfur cluster binding protein
GKQ51_04035	COG0247	lactate metabolic process
GKQ51_04040	COG1620	l-lactate permease
GKQ51_04050	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GKQ51_04060	COG2914	Belongs to the UPF0125 (RnfH) family
GKQ51_04065	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GKQ51_04075	COG0497	DNA recombination
GKQ51_04080	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GKQ51_04085	COG0443	Heat shock 70 kDa protein
GKQ51_04090	COG0484	heat shock protein binding
GKQ51_04095	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GKQ51_04120	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GKQ51_04125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GKQ51_04130	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GKQ51_04135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GKQ51_04140	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GKQ51_04155	COG0779	Required for maturation of 30S ribosomal subunits
GKQ51_04160	COG0195	Participates in both transcription termination and antitermination
GKQ51_04165	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GKQ51_04170	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GKQ51_04180	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GKQ51_04185	COG1185	polyribonucleotide nucleotidyltransferase activity
GKQ51_04205	COG0166	Belongs to the GPI family
GKQ51_04210	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GKQ51_04215	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GKQ51_04220	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GKQ51_04230	COG0617	tRNA 3'-terminal CCA addition
GKQ51_04235	COG2204	response regulator
GKQ51_04240	COG3852	Histidine kinase
GKQ51_04250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GKQ51_04255	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GKQ51_04260	COG0436	Aminotransferase
GKQ51_04265	COG1489	DNA binding
GKQ51_04275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKQ51_04295	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GKQ51_04305	COG3098	single-species biofilm formation
GKQ51_04315	COG0028	Belongs to the TPP enzyme family
GKQ51_04325	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GKQ51_04330	COG1183	phosphatidylcholine synthase activity
GKQ51_04360	COG2995	paraquat-inducible protein a
GKQ51_04365	COG2995	paraquat-inducible protein a
GKQ51_04370	COG3008	intermembrane lipid transfer
GKQ51_04375	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GKQ51_04385	COG0456	acetyltransferase
GKQ51_04400	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
GKQ51_04415	COG3135	benzoate transporter
GKQ51_04420	COG0583	DNA-binding transcription factor activity
GKQ51_04430	COG0659	secondary active sulfate transmembrane transporter activity
GKQ51_04445	COG1063	alcohol dehydrogenase
GKQ51_04455	COG0022	dehydrogenase e1 component
GKQ51_04460	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GKQ51_04465	COG3199	ATP-NAD kinase
GKQ51_04470	COG1028	Short-chain dehydrogenase reductase Sdr
GKQ51_04475	COG3284	Transcriptional regulator
GKQ51_04485	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GKQ51_04490	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
GKQ51_04500	COG0535	radical SAM domain protein
GKQ51_04510	COG1025	Belongs to the peptidase M16 family
GKQ51_04525	COG0193	aminoacyl-tRNA hydrolase activity
GKQ51_04530	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GKQ51_04550	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GKQ51_04570	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GKQ51_04580	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GKQ51_04585	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GKQ51_04590	COG0415	Belongs to the DNA photolyase family
GKQ51_04605	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
GKQ51_04610	COG1090	epimerase
GKQ51_04615	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GKQ51_04620	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GKQ51_04625	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GKQ51_04635	COG0579	oxidoreductase
GKQ51_04665	COG2135	peptidase activity
GKQ51_04670	COG0501	Belongs to the peptidase M48B family
GKQ51_04675	COG2119	membrane
GKQ51_04680	COG2119	membrane
GKQ51_04685	COG2813	Specifically methylates the guanine in position
GKQ51_04690	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKQ51_04700	COG2989	Protein conserved in bacteria
GKQ51_04710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GKQ51_04725	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GKQ51_04740	COG0386	Belongs to the glutathione peroxidase family
GKQ51_04745	COG1970	mechanosensitive ion channel activity
GKQ51_04750	COG0523	cobalamin synthesis protein
GKQ51_04755	COG2879	small protein
GKQ51_04760	COG1966	Carbon starvation protein
GKQ51_04775	COG2020	methyltransferase activity
GKQ51_04800	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GKQ51_04805	COG0488	(ABC) transporter
GKQ51_04820	COG0400	carboxylic ester hydrolase activity
GKQ51_04830	COG2827	Endonuclease containing a URI domain
GKQ51_04840	COG3081	Nucleoid-associated protein
GKQ51_04845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GKQ51_04850	COG0583	DNA-binding transcription factor activity
GKQ51_04860	COG1028	Short-chain dehydrogenase reductase Sdr
GKQ51_04865	COG0420	3'-5' exonuclease activity
GKQ51_04875	COG0419	ATPase involved in DNA repair
GKQ51_04885	COG1253	flavin adenine dinucleotide binding
GKQ51_04890	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
GKQ51_04915	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GKQ51_04920	COG0795	lipopolysaccharide-transporting ATPase activity
GKQ51_04925	COG0795	lipopolysaccharide-transporting ATPase activity
GKQ51_04935	COG1278	Cold shock
GKQ51_04990	COG1252	NADH dehydrogenase
GKQ51_05020	COG0237	dephospho-CoA kinase activity
GKQ51_05025	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GKQ51_05040	COG4969	Belongs to the N-Me-Phe pilin family
GKQ51_05045	COG1943	Transposase
GKQ51_05065	COG3023	N-Acetylmuramoyl-L-alanine amidase
GKQ51_05075	COG0084	hydrolase, TatD family'
GKQ51_05095	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GKQ51_05095	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GKQ51_05100	COG1105	Belongs to the carbohydrate kinase PfkB family
GKQ51_05105	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GKQ51_05105	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GKQ51_05105	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GKQ51_05110	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GKQ51_05115	COG0019	diaminopimelate decarboxylase activity
GKQ51_05130	COG3128	pkhd-type hydroxylase
GKQ51_05135	COG4774	siderophore transport
GKQ51_05140	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GKQ51_05150	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GKQ51_05155	COG1984	allophanate hydrolase subunit 2
GKQ51_05160	COG4608	Belongs to the ABC transporter superfamily
GKQ51_05165	COG0444	Belongs to the ABC transporter superfamily
GKQ51_05170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GKQ51_05175	COG0601	transmembrane transport
GKQ51_05180	COG0747	negative chemotaxis
GKQ51_05195	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
GKQ51_05210	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GKQ51_05215	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GKQ51_05220	COG0154	amidase activity
GKQ51_05225	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GKQ51_05230	COG1077	Cell shape determining protein MreB Mrl
GKQ51_05235	COG1792	Involved in formation and maintenance of cell shape
GKQ51_05240	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GKQ51_05245	COG0424	maF-like protein
GKQ51_05250	COG1530	ribonuclease E activity
GKQ51_05260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GKQ51_05265	COG0312	modulator of DNA gyrase
GKQ51_05270	COG3028	Belongs to the UPF0307 family
GKQ51_05275	COG0312	modulator of DNA gyrase
GKQ51_05285	COG1660	Displays ATPase and GTPase activities
GKQ51_05305	COG1137	ATPase activity
GKQ51_05310	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GKQ51_05320	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GKQ51_05330	COG1127	ABC transporter
GKQ51_05335	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GKQ51_05340	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GKQ51_05360	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GKQ51_05365	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GKQ51_05375	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GKQ51_05380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GKQ51_05390	COG0175	sulfate reduction
GKQ51_05415	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GKQ51_05420	COG1515	deoxyribonuclease V activity
GKQ51_05425	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GKQ51_05430	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GKQ51_05435	COG0723	plastoquinol--plastocyanin reductase activity
GKQ51_05440	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GKQ51_05445	COG2857	Cytochrome c1
GKQ51_05450	COG0625	glutathione transferase activity
GKQ51_05455	COG2969	positive regulation of protein catabolic process
GKQ51_05460	COG2823	Periplasmic or secreted lipoprotein
GKQ51_05465	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GKQ51_05470	COG0792	nuclease activity
GKQ51_05475	COG3107	peptidoglycan biosynthetic process
GKQ51_05490	COG2001	Belongs to the MraZ family
GKQ51_05495	COG0275	rRNA processing
GKQ51_05510	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GKQ51_05515	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GKQ51_05520	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GKQ51_05525	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GKQ51_05530	COG0772	Belongs to the SEDS family
GKQ51_05535	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GKQ51_05540	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GKQ51_05545	COG1181	Belongs to the D-alanine--D-alanine ligase family
GKQ51_05565	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GKQ51_05575	COG0653	protein targeting
GKQ51_05590	COG0494	nUDIX hydrolase
GKQ51_05595	COG2096	Adenosyltransferase
GKQ51_05600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GKQ51_05600	COG4191	Histidine kinase
GKQ51_05610	COG1666	GTP binding
GKQ51_05625	COG1028	Short-chain dehydrogenase reductase Sdr
GKQ51_05635	COG3030	protein affecting phage T7 exclusion by the F plasmid
GKQ51_05650	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GKQ51_05685	COG1024	Enoyl-CoA hydratase
GKQ51_05695	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GKQ51_05750	COG3086	response to oxidative stress
GKQ51_05755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GKQ51_05760	COG0481	GTPase activity
GKQ51_05775	COG0571	ribonuclease III activity
GKQ51_05780	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GKQ51_05785	COG1381	Involved in DNA repair and RecF pathway recombination
GKQ51_05790	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GKQ51_05800	COG0500	methyltransferase
GKQ51_05805	COG2226	methyltransferase
GKQ51_05815	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GKQ51_05835	COG0583	DNA-binding transcription factor activity
GKQ51_05845	COG2267	carboxylic ester hydrolase activity
GKQ51_05860	COG3842	ATPase activity
GKQ51_05870	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GKQ51_05885	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GKQ51_05890	COG0418	dihydroorotase activity
GKQ51_05895	COG0137	argininosuccinate synthase activity
GKQ51_05955	COG0521	Mo-molybdopterin cofactor biosynthetic process
GKQ51_05960	COG0303	'Molybdopterin
GKQ51_05975	COG0488	(ABC) transporter
GKQ51_05985	COG0589	response to stress
GKQ51_05990	COG2814	Major facilitator Superfamily
GKQ51_06000	COG1024	Enoyl-CoA hydratase
GKQ51_06005	COG1012	belongs to the aldehyde dehydrogenase family
GKQ51_06015	COG0183	Belongs to the thiolase family
GKQ51_06020	COG1960	acyl-CoA dehydrogenase activity
GKQ51_06055	COG1024	Enoyl-CoA hydratase
GKQ51_06055	COG1250	3-hydroxyacyl-CoA dehydrogenase
GKQ51_06060	COG0183	Belongs to the thiolase family
GKQ51_06090	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GKQ51_06110	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GKQ51_06120	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GKQ51_06140	COG1805	sodium ion transport
GKQ51_06165	COG1477	protein flavinylation
GKQ51_06175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GKQ51_06180	COG0584	glycerophosphoryl diester phosphodiesterase
GKQ51_06185	COG4591	ABC-type transport system involved in lipoprotein release permease component
GKQ51_06190	COG1136	(ABC) transporter
GKQ51_06195	COG4591	ABC-type transport system involved in lipoprotein release permease component
GKQ51_06205	COG2333	competence protein COMEC
GKQ51_06205	COG0658	competence protein
GKQ51_06210	COG0811	peptide transport
GKQ51_06215	COG0848	biopolymer transport protein
GKQ51_06220	COG1663	tetraacyldisaccharide 4'-kinase activity
GKQ51_06225	COG2835	tetraacyldisaccharide 4'-kinase activity
GKQ51_06230	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GKQ51_06235	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GKQ51_06240	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GKQ51_06245	COG1530	ribonuclease E activity
GKQ51_06255	COG0546	phosphoglycolate phosphatase activity
GKQ51_06260	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GKQ51_06260	COG0616	signal peptide processing
GKQ51_06265	COG0424	maF-like protein
GKQ51_06275	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GKQ51_06280	COG0416	fatty acid biosynthetic process
GKQ51_06295	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKQ51_06300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GKQ51_06310	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GKQ51_06315	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GKQ51_06330	COG0084	hydrolase, TatD family'
GKQ51_06345	COG1355	regulation of microtubule-based process
GKQ51_06355	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GKQ51_06360	COG2267	carboxylic ester hydrolase activity
GKQ51_06365	COG1414	Transcriptional regulator
GKQ51_06370	COG3971	2-oxopent-4-enoate hydratase activity
GKQ51_06375	COG4569	acetaldehyde dehydrogenase (acetylating) activity
GKQ51_06380	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GKQ51_06385	COG2814	Major facilitator Superfamily
GKQ51_06430	COG5002	protein histidine kinase activity
GKQ51_06450	COG3135	benzoate transporter
GKQ51_06475	COG1764	response to oxidative stress
GKQ51_06480	COG1846	Transcriptional regulator
GKQ51_06490	COG0730	response to heat
GKQ51_06500	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
GKQ51_06510	COG0583	DNA-binding transcription factor activity
GKQ51_06525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKQ51_06545	COG0625	glutathione transferase activity
GKQ51_06575	COG0500	methyltransferase
GKQ51_06595	COG0436	Aminotransferase
GKQ51_06600	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GKQ51_06605	COG0386	Belongs to the glutathione peroxidase family
GKQ51_06610	COG3437	response regulator, receiver
GKQ51_06610	COG4999	Histidine kinase
GKQ51_06610	COG3850	Histidine kinase
GKQ51_06610	COG2205	protein histidine kinase activity
GKQ51_06645	COG1131	(ABC) transporter
GKQ51_06650	COG0842	Transport permease protein
GKQ51_06665	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GKQ51_06665	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GKQ51_06670	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GKQ51_06675	COG0727	PFAM Uncharacterised protein family (UPF0153)
GKQ51_06680	COG0778	Nitroreductase
GKQ51_06685	COG0642	Histidine kinase
GKQ51_06695	COG0745	RESPONSE REGULATOR receiver
GKQ51_06700	COG2350	Protein conserved in bacteria
GKQ51_06705	COG2917	probably involved in intracellular septation
GKQ51_06710	COG0613	PHP domain protein
GKQ51_06715	COG0009	L-threonylcarbamoyladenylate synthase
GKQ51_06720	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GKQ51_06725	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GKQ51_06750	COG0800	Aldolase
GKQ51_06760	COG1028	Short-chain dehydrogenase reductase Sdr
GKQ51_06765	COG0546	phosphoglycolate phosphatase activity
GKQ51_06770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GKQ51_06775	COG0402	S-adenosylhomocysteine deaminase activity
GKQ51_06780	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GKQ51_06790	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GKQ51_06805	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GKQ51_06810	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GKQ51_06830	COG0776	regulation of translation
GKQ51_06870	COG1538	Outer membrane efflux protein
GKQ51_06900	COG0463	Glycosyl transferase, family 2
GKQ51_06915	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GKQ51_06945	COG1091	dTDP-4-dehydrorhamnose reductase activity
GKQ51_06980	COG1215	transferase activity, transferring glycosyl groups
GKQ51_06985	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GKQ51_07010	COG1216	Glycosyl transferase, family 2
GKQ51_07010	COG0438	transferase activity, transferring glycosyl groups
GKQ51_07030	COG0438	transferase activity, transferring glycosyl groups
GKQ51_07035	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GKQ51_07040	COG1643	Atp-dependent helicase
GKQ51_07045	COG0840	transmembrane signaling receptor activity
GKQ51_07060	COG2161	toxin-antitoxin pair type II binding
GKQ51_07080	COG2814	Major facilitator Superfamily
GKQ51_07090	COG0183	Belongs to the thiolase family
GKQ51_07095	COG1024	Enoyl-CoA hydratase
GKQ51_07095	COG1250	3-hydroxyacyl-CoA dehydrogenase
GKQ51_07100	COG1960	acyl-CoA dehydrogenase activity
GKQ51_07120	COG0427	acetyl-CoA hydrolase
GKQ51_07125	COG0427	acetyl-CoA hydrolase
GKQ51_07130	COG1621	beta-fructofuranosidase activity
GKQ51_07135	COG0583	DNA-binding transcription factor activity
GKQ51_07155	COG0842	Transport permease protein
GKQ51_07160	COG0842	Transport permease protein
GKQ51_07160	COG1129	ABC transporter
GKQ51_07165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GKQ51_07175	COG1063	alcohol dehydrogenase
GKQ51_07210	COG4221	oxidoreductase activity
GKQ51_07220	COG2133	pyrroloquinoline quinone binding
GKQ51_07260	COG0438	transferase activity, transferring glycosyl groups
GKQ51_07275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GKQ51_07290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GKQ51_07305	COG2031	fatty acid transporter
GKQ51_07310	COG1028	Short-chain dehydrogenase reductase Sdr
GKQ51_07315	COG2610	gluconate transmembrane transporter activity
GKQ51_07320	COG3829	transcription factor binding
GKQ51_07320	COG3290	protein histidine kinase activity
GKQ51_07330	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GKQ51_07345	COG0166	Belongs to the GPI family
GKQ51_07350	COG0738	Major facilitator superfamily
GKQ51_07380	COG3642	lipopolysaccharide core region biosynthetic process
GKQ51_07390	COG0642	Histidine kinase
GKQ51_07395	COG0745	RESPONSE REGULATOR receiver
GKQ51_07410	COG3002	Belongs to the UPF0753 family
GKQ51_07415	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GKQ51_07445	COG1278	Cold shock
GKQ51_07465	COG1403	HNH endonuclease
GKQ51_07470	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GKQ51_07475	COG4191	Histidine kinase
GKQ51_07480	COG2204	response regulator
GKQ51_07485	COG0477	Major facilitator Superfamily
GKQ51_07490	COG2358	TRAP transporter, solute receptor (TAXI family
GKQ51_07515	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GKQ51_07520	COG0450	alkyl hydroperoxide reductase
GKQ51_07525	COG0431	NADPH-dependent FMN reductase
GKQ51_07530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GKQ51_07535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GKQ51_07540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GKQ51_07545	COG1116	anion transmembrane transporter activity
GKQ51_07570	COG2032	superoxide dismutase activity
GKQ51_07600	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GKQ51_07630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GKQ51_07635	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GKQ51_07645	COG3115	cell septum assembly
GKQ51_07650	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GKQ51_07670	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GKQ51_07685	COG3181	Tripartite tricarboxylate transporter family receptor
GKQ51_07700	COG3293	Transposase
GKQ51_07725	COG0673	inositol 2-dehydrogenase activity
GKQ51_07750	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GKQ51_07755	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GKQ51_07770	COG1294	oxidase, subunit
GKQ51_07785	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GKQ51_07815	COG0348	domain, Protein
GKQ51_07820	COG2010	Cytochrome c
GKQ51_07835	COG3278	Belongs to the heme-copper respiratory oxidase family
GKQ51_07850	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
GKQ51_07860	COG1555	photosystem II stabilization
GKQ51_07880	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GKQ51_07885	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GKQ51_07895	COG0564	pseudouridine synthase activity
GKQ51_07900	COG0071	Belongs to the small heat shock protein (HSP20) family
GKQ51_07905	COG0679	Auxin Efflux Carrier
GKQ51_07915	COG1414	Transcriptional regulator
GKQ51_07920	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GKQ51_07925	COG1053	succinate dehydrogenase
GKQ51_07935	COG1053	succinate dehydrogenase
GKQ51_07955	COG1063	alcohol dehydrogenase
GKQ51_08010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GKQ51_08110	COG2356	endonuclease I
GKQ51_08190	COG1598	PFAM Uncharacterised protein family UPF0150
GKQ51_08195	COG1724	mRNA binding
GKQ51_08340	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GKQ51_08350	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GKQ51_08355	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GKQ51_08360	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GKQ51_08365	COG0072	phenylalanine-tRNA ligase activity
GKQ51_08370	COG0776	regulation of translation
GKQ51_08400	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GKQ51_08405	COG4396	Host-nuclease inhibitor protein Gam
GKQ51_08420	COG0145	ligase activity
GKQ51_08425	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
GKQ51_08430	COG4647	ligase activity
GKQ51_08445	COG0515	serine threonine protein kinase
GKQ51_08460	COG1045	serine acetyltransferase
GKQ51_08465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GKQ51_08470	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GKQ51_08485	COG1024	Enoyl-CoA hydratase
GKQ51_08505	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
GKQ51_08510	COG4266	Belongs to the allantoicase family
GKQ51_08515	COG1126	abc transporter atp-binding protein
GKQ51_08520	COG0765	amino acid transport
GKQ51_08565	COG4566	intracellular signal transduction
GKQ51_08570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GKQ51_08575	COG0318	PFAM AMP-dependent synthetase and ligase
GKQ51_08580	COG0402	S-adenosylhomocysteine deaminase activity
GKQ51_08600	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GKQ51_08610	COG0667	Aldo Keto reductase
GKQ51_08630	COG3265	gluconokinase activity
GKQ51_08660	COG3585	molybdate ion transport
GKQ51_08665	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GKQ51_08670	COG0625	glutathione transferase activity
GKQ51_08675	COG4774	siderophore transport
GKQ51_08680	COG3712	iron ion homeostasis
GKQ51_08685	COG1595	DNA-templated transcription, initiation
GKQ51_08725	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GKQ51_08745	COG0753	catalase activity
GKQ51_08750	COG0783	Belongs to the Dps family
GKQ51_08820	COG3267	Type II secretory pathway component ExeA
GKQ51_08820	COG3409	Peptidoglycan-binding domain 1 protein
GKQ51_08845	COG0714	Associated with various cellular activities
GKQ51_08865	COG1469	GTP cyclohydrolase I activity
GKQ51_08880	COG0084	hydrolase, TatD family'
GKQ51_08885	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GKQ51_08900	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GKQ51_08905	COG4181	ATPase activity
GKQ51_08955	COG0189	ligase activity
GKQ51_08970	COG1802	Transcriptional regulator
GKQ51_08995	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GKQ51_09005	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GKQ51_09015	COG0668	transmembrane transport
GKQ51_09035	COG0243	molybdopterin cofactor binding
GKQ51_09040	COG2146	nitrite reductase [NAD(P)H] activity
GKQ51_09045	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GKQ51_09050	COG0515	serine threonine protein kinase
GKQ51_09050	COG2815	serine threonine protein kinase
GKQ51_09055	COG2223	nitrite transmembrane transporter activity
GKQ51_09075	COG0436	Aminotransferase
GKQ51_09085	COG3707	response regulator
GKQ51_09090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GKQ51_09155	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GKQ51_09165	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GKQ51_09170	COG0215	cysteine-tRNA ligase activity
GKQ51_09180	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GKQ51_09200	COG4974	Belongs to the 'phage' integrase family
GKQ51_09365	COG0305	Participates in initiation and elongation during chromosome replication
GKQ51_09620	COG0544	peptidyl-prolyl cis-trans isomerase activity
GKQ51_09630	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GKQ51_09635	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GKQ51_09645	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GKQ51_09650	COG3243	poly(R)-hydroxyalkanoic acid synthase
GKQ51_09660	COG1028	Short-chain dehydrogenase reductase Sdr
GKQ51_09675	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
GKQ51_09685	COG0302	gtp cyclohydrolase
GKQ51_09720	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GKQ51_09730	COG0235	Class ii aldolase
GKQ51_09740	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
GKQ51_09750	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GKQ51_09765	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GKQ51_09800	COG1815	bacterial-type flagellum-dependent cell motility
GKQ51_09805	COG1558	bacterial-type flagellum-dependent cell motility
GKQ51_09810	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GKQ51_09815	COG1749	Flagellar hook protein flgE
GKQ51_09820	COG4787	bacterial-type flagellum-dependent cell motility
GKQ51_09830	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GKQ51_09835	COG1706	bacterial-type flagellum-dependent cell motility
GKQ51_09860	COG1987	bacterial-type flagellum assembly
GKQ51_09880	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GKQ51_09920	COG1677	Flagellar hook-basal body complex protein FliE
GKQ51_09925	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GKQ51_09945	COG2257	FlhB HrpN YscU SpaS Family
GKQ51_09970	COG1360	Flagellar Motor Protein
GKQ51_09980	COG0835	chemotaxis
GKQ51_09985	COG0840	transmembrane signaling receptor activity
GKQ51_09990	COG0840	transmembrane signaling receptor activity
GKQ51_09995	COG0840	transmembrane signaling receptor activity
GKQ51_10005	COG2201	protein-glutamate methylesterase activity
GKQ51_10010	COG0840	transmembrane signaling receptor activity
GKQ51_10015	COG0840	transmembrane signaling receptor activity
GKQ51_10020	COG0840	transmembrane signaling receptor activity
GKQ51_10025	COG0745	RESPONSE REGULATOR receiver
GKQ51_10030	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GKQ51_10035	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GKQ51_10040	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GKQ51_10065	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GKQ51_10075	COG5654	RES domain protein
GKQ51_10080	COG5642	Protein of unknown function (DUF2384)
GKQ51_10105	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GKQ51_10190	COG2816	NAD+ diphosphatase activity
GKQ51_10205	COG0616	signal peptide processing
GKQ51_10215	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GKQ51_10225	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GKQ51_10260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GKQ51_10270	COG2706	6-phosphogluconolactonase activity
GKQ51_10275	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GKQ51_10280	COG3265	gluconokinase activity
GKQ51_10285	COG1609	Transcriptional regulator
GKQ51_10305	COG0800	Aldolase
GKQ51_10310	COG0469	pyruvate kinase activity
GKQ51_10320	COG0148	phosphopyruvate hydratase activity
GKQ51_10335	COG4580	involved in the transport of maltose and maltodextrins
GKQ51_10340	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GKQ51_10370	COG3064	Membrane
GKQ51_10380	COG3039	Transposase
GKQ51_10410	COG0246	Mannitol dehydrogenase
GKQ51_10430	COG1216	Glycosyl transferase, family 2
GKQ51_10435	COG1064	alcohol dehydrogenase
GKQ51_10455	COG1064	alcohol dehydrogenase
GKQ51_10480	COG0583	DNA-binding transcription factor activity
GKQ51_10490	COG0483	inositol monophosphate 1-phosphatase activity
GKQ51_10500	COG1012	belongs to the aldehyde dehydrogenase family
GKQ51_10505	COG2721	sulfolactate sulfo-lyase activity
GKQ51_10510	COG0583	DNA-binding transcription factor activity
GKQ51_10520	COG2271	Major facilitator Superfamily
GKQ51_10540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GKQ51_10550	COG1609	Transcriptional regulator
GKQ51_10600	COG1611	Belongs to the LOG family
GKQ51_10610	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GKQ51_10610	COG0574	Belongs to the PEP-utilizing enzyme family
GKQ51_10660	COG0402	S-adenosylhomocysteine deaminase activity
GKQ51_10665	COG2986	histidine ammonia-lyase
GKQ51_10675	COG5642	Protein of unknown function (DUF2384)
GKQ51_10705	COG4689	acetoacetate decarboxylase
GKQ51_10715	COG1028	Short-chain dehydrogenase reductase Sdr
GKQ51_10720	COG1252	NADH dehydrogenase
GKQ51_10745	COG0745	RESPONSE REGULATOR receiver
GKQ51_10750	COG5002	protein histidine kinase activity
GKQ51_10760	COG3220	belongs to the UPF0276 family
GKQ51_10770	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GKQ51_10820	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GKQ51_10825	COG1760	l-serine dehydratase
GKQ51_10830	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GKQ51_10830	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GKQ51_10840	COG0183	Belongs to the thiolase family
GKQ51_10850	COG0701	Predicted permease
GKQ51_10860	COG0798	PFAM Bile acid sodium symporter
GKQ51_10865	COG0640	Transcriptional regulator
GKQ51_10870	COG0431	NADPH-dependent FMN reductase
GKQ51_10880	COG1742	UPF0060 membrane protein
GKQ51_10885	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GKQ51_10895	COG2217	Heavy metal translocating P-type atpase
GKQ51_10925	COG3829	transcription factor binding
GKQ51_10935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GKQ51_10945	COG0626	cystathionine gamma-synthase activity
GKQ51_10955	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GKQ51_10955	COG2010	Cytochrome c
GKQ51_10960	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GKQ51_10975	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
GKQ51_10980	COG0589	response to stress
GKQ51_10985	COG0459	protein refolding
GKQ51_10990	COG0071	Belongs to the small heat shock protein (HSP20) family
GKQ51_11015	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GKQ51_11040	COG1960	acyl-CoA dehydrogenase activity
GKQ51_11050	COG0069	glutamate synthase activity
GKQ51_11060	COG1752	Esterase of the alpha-beta hydrolase superfamily
GKQ51_11065	COG1309	transcriptional regulator
GKQ51_11070	COG4566	intracellular signal transduction
GKQ51_11090	COG0655	NAD(P)H dehydrogenase (quinone) activity
GKQ51_11150	COG0318	PFAM AMP-dependent synthetase and ligase
GKQ51_11160	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GKQ51_11165	COG1250	3-hydroxyacyl-CoA dehydrogenase
GKQ51_11170	COG1960	acyl-CoA dehydrogenase activity
GKQ51_11230	COG3299	homolog of phage Mu protein gp47
GKQ51_11270	COG4386	tail sheath protein
GKQ51_11390	COG2932	Transcriptional regulator
GKQ51_11395	COG2356	endonuclease I
GKQ51_11465	COG0582	viral genome integration into host DNA
GKQ51_11490	COG0322	excinuclease ABC activity
GKQ51_11530	COG0659	secondary active sulfate transmembrane transporter activity
GKQ51_11540	COG0297	glycogen (starch) synthase activity
GKQ51_11545	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GKQ51_11580	COG3568	Endonuclease Exonuclease Phosphatase
GKQ51_11585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKQ51_11590	COG0392	lysyltransferase activity
GKQ51_11600	COG0604	alcohol dehydrogenase
GKQ51_11605	COG0583	DNA-binding transcription factor activity
GKQ51_11620	COG3158	transport of potassium into the cell
GKQ51_11625	COG0745	RESPONSE REGULATOR receiver
GKQ51_11630	COG2205	protein histidine kinase activity
GKQ51_11635	COG3046	protein related to deoxyribodipyrimidine photolyase
GKQ51_11665	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GKQ51_11670	COG0366	Alpha amylase catalytic
GKQ51_11705	COG2920	part of a sulfur-relay system
GKQ51_11710	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GKQ51_11715	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GKQ51_11715	COG1648	precorrin-2 dehydrogenase activity
GKQ51_11725	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GKQ51_11730	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GKQ51_11735	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GKQ51_11745	COG0492	ferredoxin-NADP+ reductase activity
GKQ51_11750	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GKQ51_11755	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GKQ51_11760	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GKQ51_11765	COG0542	response to heat
GKQ51_11770	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GKQ51_11775	COG1278	Cold shock
GKQ51_11790	COG0482	sulfurtransferase activity
GKQ51_11795	COG2915	High frequency lysogenization protein hflD homolog
GKQ51_11805	COG2850	peptidyl-arginine hydroxylation
GKQ51_11810	COG2153	protein acetylation
GKQ51_11830	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GKQ51_11835	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GKQ51_11840	COG0649	NAD binding
GKQ51_11840	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GKQ51_11860	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GKQ51_11865	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GKQ51_11875	COG0713	ATP synthesis coupled electron transport
GKQ51_11890	COG1007	ATP synthesis coupled electron transport
GKQ51_11910	COG0720	synthase
GKQ51_11915	COG0741	lytic transglycosylase activity
GKQ51_11925	COG1459	type II secretion system
GKQ51_11940	COG2135	peptidase activity
GKQ51_11945	COG0488	(ABC) transporter
GKQ51_11955	COG1278	Cold shock
GKQ51_11960	COG1968	undecaprenyl-diphosphatase activity
GKQ51_11980	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GKQ51_11980	COG0316	Belongs to the HesB IscA family
GKQ51_11990	COG1538	Outer membrane efflux protein
GKQ51_12010	COG0697	spore germination
GKQ51_12015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GKQ51_12025	COG1115	amino acid carrier protein
GKQ51_12030	COG2911	Protein conserved in bacteria
GKQ51_12035	COG0729	surface antigen
GKQ51_12050	COG2885	chlorophyll binding
GKQ51_12060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GKQ51_12085	COG1621	beta-fructofuranosidase activity
GKQ51_12095	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
GKQ51_12105	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GKQ51_12115	COG4191	Histidine kinase
GKQ51_12125	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GKQ51_12130	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GKQ51_12145	COG2165	general secretion pathway protein
GKQ51_12185	COG0745	RESPONSE REGULATOR receiver
GKQ51_12190	COG1234	tRNA 3'-trailer cleavage
GKQ51_12285	COG0513	Belongs to the DEAD box helicase family
GKQ51_12295	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GKQ51_12315	COG0500	methyltransferase
GKQ51_12325	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GKQ51_12350	COG1136	(ABC) transporter
GKQ51_12350	COG0577	efflux transmembrane transporter activity
GKQ51_12385	COG0328	RNA-DNA hybrid ribonuclease activity
GKQ51_12395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GKQ51_12400	COG1388	LysM domain
GKQ51_12400	COG0741	lytic transglycosylase activity
GKQ51_12410	COG4166	transmembrane transport
GKQ51_12415	COG4174	ABC transporter (Permease)
GKQ51_12420	COG4239	(ABC) transporter, permease
GKQ51_12425	COG4172	Belongs to the ABC transporter superfamily
GKQ51_12435	COG2233	PERMEase
GKQ51_12440	COG0697	spore germination
GKQ51_12455	COG0045	succinate-CoA ligase (ADP-forming) activity
GKQ51_12485	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GKQ51_12490	COG2009	succinate dehydrogenase
GKQ51_12515	COG3123	guanosine phosphorylase activity
GKQ51_12525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GKQ51_12545	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GKQ51_12550	COG3206	protein involved in exopolysaccharide biosynthesis
GKQ51_12550	COG0489	protein tyrosine kinase activity
GKQ51_12555	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GKQ51_12560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GKQ51_12565	COG1132	(ABC) transporter
GKQ51_12595	COG0463	Glycosyl transferase, family 2
GKQ51_12605	COG1215	transferase activity, transferring glycosyl groups
GKQ51_12615	COG0438	transferase activity, transferring glycosyl groups
GKQ51_12620	COG0438	transferase activity, transferring glycosyl groups
GKQ51_12640	COG0438	transferase activity, transferring glycosyl groups
GKQ51_12645	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GKQ51_12655	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GKQ51_12660	COG0463	Glycosyl transferase, family 2
GKQ51_12705	COG1442	glycosyl transferase family 8
GKQ51_12705	COG1216	Glycosyl transferase, family 2
GKQ51_12715	COG1216	Glycosyl transferase, family 2
GKQ51_12715	COG1442	glycosyl transferase family 8
GKQ51_12720	COG1442	glycosyl transferase family 8
GKQ51_12720	COG1216	Glycosyl transferase, family 2
GKQ51_12755	COG0489	protein tyrosine kinase activity
GKQ51_12785	COG0438	transferase activity, transferring glycosyl groups
GKQ51_12790	COG4763	Acyl-transferase
GKQ51_12805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GKQ51_12825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GKQ51_12840	COG0318	PFAM AMP-dependent synthetase and ligase
GKQ51_12845	COG2030	dehydratase
GKQ51_12855	COG0402	S-adenosylhomocysteine deaminase activity
GKQ51_12860	COG2207	Transcriptional regulator
GKQ51_12865	COG3622	Belongs to the hyi family
GKQ51_12875	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GKQ51_12885	COG3639	organic phosphonate transmembrane transporter activity
GKQ51_12935	COG1320	monovalent cation:proton antiporter activity
GKQ51_12940	COG2212	antiporter activity
GKQ51_12950	COG0651	ATP synthesis coupled electron transport
GKQ51_12955	COG1006	Multisubunit Na H antiporter MnhC subunit
GKQ51_12960	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GKQ51_12960	COG2111	Na H antiporter
GKQ51_12965	COG3133	Outer membrane lipoprotein
GKQ51_12980	COG4221	oxidoreductase activity
GKQ51_12985	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GKQ51_13000	COG2175	clavaminate synthase activity
GKQ51_13010	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GKQ51_13020	COG0583	DNA-binding transcription factor activity
GKQ51_13065	COG1960	acyl-CoA dehydrogenase activity
GKQ51_13080	COG1116	anion transmembrane transporter activity
GKQ51_13085	COG1929	Belongs to the glycerate kinase type-1 family
GKQ51_13095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GKQ51_13110	COG0235	Class ii aldolase
GKQ51_13120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GKQ51_13125	COG1902	pentaerythritol trinitrate reductase activity
GKQ51_13130	COG0640	Transcriptional regulator
GKQ51_13135	COG2814	Major facilitator Superfamily
GKQ51_13140	COG0583	DNA-binding transcription factor activity
GKQ51_13145	COG1335	isochorismatase
GKQ51_13180	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GKQ51_13185	COG2011	ABC-type metal ion transport system permease component
GKQ51_13205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GKQ51_13225	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GKQ51_13235	COG4208	sulfate ABC transporter
GKQ51_13245	COG3781	membrane
GKQ51_13385	COG3436	PFAM IS66 Orf2 family protein
GKQ51_13390	COG4372	Transposase
GKQ51_13420	COG2026	Addiction module toxin, RelE StbE family
GKQ51_13430	COG3941	tape measure
GKQ51_13465	COG0616	signal peptide processing
GKQ51_13510	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GKQ51_13520	COG0745	RESPONSE REGULATOR receiver
GKQ51_13525	COG2853	Lipoprotein
GKQ51_13565	COG0514	ATP-dependent DNA helicase (RecQ)
GKQ51_13575	COG2832	Protein of unknown function (DUF454)
GKQ51_13595	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GKQ51_13600	COG0542	response to heat
GKQ51_13610	COG0121	glutamine amidotransferase
GKQ51_13625	COG1295	ribonuclease BN
GKQ51_13630	COG2703	oxygen carrier activity
GKQ51_13640	COG2983	Belongs to the UPF0260 family
GKQ51_13655	COG3100	YcgL domain-containing protein
GKQ51_13665	COG1621	beta-fructofuranosidase activity
GKQ51_13695	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GKQ51_13700	COG0406	alpha-ribazole phosphatase activity
GKQ51_13705	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GKQ51_13715	COG1492	cobalamin metabolic process
GKQ51_13725	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GKQ51_13730	COG0778	Nitroreductase
GKQ51_13735	COG1797	cobyrinic acid a,c-diamide synthase activity
GKQ51_13750	COG4206	TonB-dependent receptor
GKQ51_13755	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GKQ51_13760	COG0519	Catalyzes the synthesis of GMP from XMP
GKQ51_13765	COG0791	NLP P60 protein
GKQ51_13770	COG0791	NLP P60 protein
GKQ51_13785	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GKQ51_13790	COG0037	tRNA processing
GKQ51_13800	COG3091	SprT-like family
GKQ51_13820	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GKQ51_13820	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKQ51_13825	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKQ51_13840	COG3436	PFAM IS66 Orf2 family protein
GKQ51_13845	COG4372	Transposase
GKQ51_13865	COG2226	methyltransferase
GKQ51_13900	COG0826	peptidase U32
GKQ51_13915	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GKQ51_13920	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GKQ51_13935	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GKQ51_13960	COG0217	transcriptional regulatory protein
GKQ51_13995	COG2824	Alkylphosphonate utilization operon protein PhnA
GKQ51_14000	COG3416	Protein conserved in bacteria
GKQ51_14020	COG0259	pyridoxamine-phosphate oxidase activity
GKQ51_14025	COG2885	chlorophyll binding
GKQ51_14030	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GKQ51_14040	COG2111	Na H antiporter
GKQ51_14040	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GKQ51_14045	COG1006	Multisubunit Na H antiporter MnhC subunit
GKQ51_14050	COG0651	ATP synthesis coupled electron transport
GKQ51_14055	COG1863	multisubunit Na H antiporter MnhE subunit
GKQ51_14065	COG1320	monovalent cation:proton antiporter activity
GKQ51_14070	COG1199	ATP-dependent helicase activity
GKQ51_14090	COG3012	SEC-C Motif Domain Protein
GKQ51_14140	COG1566	PFAM secretion protein HlyD family protein
GKQ51_14160	COG0717	Belongs to the dCTP deaminase family
GKQ51_14200	COG0489	protein tyrosine kinase activity
GKQ51_14205	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GKQ51_14205	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GKQ51_14210	COG4657	Part of a membrane complex involved in electron transport
GKQ51_14215	COG2878	Part of a membrane complex involved in electron transport
GKQ51_14225	COG4658	electron transport chain
GKQ51_14230	COG4659	FMN binding
GKQ51_14240	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GKQ51_14300	COG0583	DNA-binding transcription factor activity
GKQ51_14305	COG5265	(ABC) transporter
GKQ51_14310	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GKQ51_14315	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
GKQ51_14320	COG0513	Belongs to the DEAD box helicase family
GKQ51_14330	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GKQ51_14360	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GKQ51_14380	COG1857	crispr-associated protein
GKQ51_14410	COG1525	nuclease
GKQ51_14445	COG2027	D-alanyl-D-alanine carboxypeptidase
GKQ51_14450	COG0116	Belongs to the methyltransferase superfamily
GKQ51_14450	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GKQ51_14455	COG3130	regulation of translation
GKQ51_14460	COG0167	dihydroorotate dehydrogenase activity
GKQ51_14490	COG0714	Associated with various cellular activities
GKQ51_14525	COG0427	acetyl-CoA hydrolase
GKQ51_14530	COG0308	aminopeptidase N
GKQ51_14540	COG3139	Protein of unknown function (DUF1315)
GKQ51_14550	COG2900	Belongs to the SlyX family
GKQ51_14560	COG0642	Histidine kinase
GKQ51_14600	COG0705	Rhomboid family
GKQ51_14605	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GKQ51_14610	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GKQ51_14660	COG1286	toxin biosynthetic process
GKQ51_14670	COG0285	dihydrofolate synthase activity
GKQ51_14680	COG0135	phosphoribosylanthranilate isomerase activity
GKQ51_14715	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GKQ51_14735	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GKQ51_14745	COG0800	Aldolase
GKQ51_14755	COG0745	RESPONSE REGULATOR receiver
GKQ51_14790	COG2239	Acts as a magnesium transporter
GKQ51_14815	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GKQ51_14820	COG0527	aspartate kinase activity
GKQ51_14825	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GKQ51_14850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GKQ51_14860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GKQ51_14865	COG2301	Belongs to the HpcH HpaI aldolase family
GKQ51_14905	COG2154	pterin-4-alpha-carbinolamine dehydratase
GKQ51_14985	COG0271	Belongs to the BolA IbaG family
GKQ51_15020	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GKQ51_15020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GKQ51_15025	COG1846	Transcriptional regulator
GKQ51_15030	COG0367	asparagine synthase
GKQ51_15035	COG0189	ligase activity
GKQ51_15035	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GKQ51_15040	COG1363	Peptidase, m42
GKQ51_15050	COG3089	Belongs to the UPF0270 family
GKQ51_15060	COG1253	flavin adenine dinucleotide binding
GKQ51_15065	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GKQ51_15070	COG3162	membrane
GKQ51_15095	COG2853	Lipoprotein
GKQ51_15100	COG1560	Kdo2-lipid A biosynthetic process
GKQ51_15105	COG0850	regulation of cytokinetic process
GKQ51_15110	COG2894	cell division
GKQ51_15115	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GKQ51_15120	COG0564	pseudouridine synthase activity
GKQ51_15125	COG1362	aminopeptidase activity
GKQ51_15150	COG3339	Conserved Protein
GKQ51_15155	COG0545	Peptidyl-prolyl cis-trans isomerase
GKQ51_15175	COG2205	protein histidine kinase activity
GKQ51_15180	COG3174	membrane
GKQ51_15220	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GKQ51_15225	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GKQ51_15240	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GKQ51_15245	COG0425	Belongs to the sulfur carrier protein TusA family
GKQ51_15250	COG4783	chaperone-mediated protein folding
GKQ51_15255	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GKQ51_15270	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GKQ51_15275	COG0602	queuosine metabolic process
GKQ51_15280	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GKQ51_15310	COG0824	Thioesterase
GKQ51_15315	COG2255	four-way junction helicase activity
GKQ51_15325	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GKQ51_15335	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GKQ51_15345	COG0442	prolyl-tRNA aminoacylation
GKQ51_15370	COG1295	ribonuclease BN
GKQ51_15390	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GKQ51_15395	COG0628	permease
GKQ51_15410	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GKQ51_15415	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GKQ51_15425	COG3122	Protein conserved in bacteria
GKQ51_15430	COG3956	TIGRFAM MazG family protein
GKQ51_15485	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GKQ51_15500	COG2205	protein histidine kinase activity
GKQ51_15500	COG5002	protein histidine kinase activity
GKQ51_15500	COG0784	Response regulator, receiver
GKQ51_15505	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GKQ51_15535	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GKQ51_15550	COG2308	Evidence 4 Homologs of previously reported genes of
GKQ51_15555	COG0693	protein deglycase activity
GKQ51_15560	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKQ51_15590	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
GKQ51_15600	COG1902	pentaerythritol trinitrate reductase activity
GKQ51_15640	COG2831	hemolysin activation secretion protein
GKQ51_15695	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GKQ51_15700	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GKQ51_15705	COG1309	transcriptional regulator
GKQ51_15710	COG1082	Xylose isomerase domain protein TIM barrel
GKQ51_15710	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GKQ51_15725	COG1053	succinate dehydrogenase
GKQ51_15730	COG0656	L-ascorbic acid biosynthetic process
GKQ51_15735	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GKQ51_15740	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GKQ51_15755	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GKQ51_15760	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GKQ51_15765	COG1414	Transcriptional regulator
GKQ51_15770	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GKQ51_15775	COG3485	protocatechuate 3,4-dioxygenase
GKQ51_15780	COG3485	protocatechuate 3,4-dioxygenase
GKQ51_15785	COG0583	DNA-binding transcription factor activity
GKQ51_15790	COG0788	formyltetrahydrofolate deformylase activity
GKQ51_15800	COG2925	Exonuclease
GKQ51_15825	COG0714	Associated with various cellular activities
GKQ51_15840	COG0589	response to stress
GKQ51_15850	COG3706	GGDEF domain
GKQ51_15855	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GKQ51_15855	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GKQ51_15870	COG0583	DNA-binding transcription factor activity
GKQ51_15880	COG3148	PFAM DTW domain containing protein
GKQ51_15890	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
GKQ51_15895	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GKQ51_15905	COG2137	regulation of response to DNA damage stimulus
GKQ51_15910	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GKQ51_15915	COG1546	Belongs to the CinA family
GKQ51_15920	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GKQ51_15945	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GKQ51_15950	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GKQ51_15955	COG0585	pseudouridine synthase activity
GKQ51_15960	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GKQ51_15965	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GKQ51_15970	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GKQ51_15975	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GKQ51_15990	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GKQ51_15995	COG0504	CTP synthase activity
GKQ51_16005	COG0825	malonyl-CoA metabolic process
GKQ51_16015	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GKQ51_16020	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GKQ51_16025	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GKQ51_16030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GKQ51_16055	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GKQ51_16065	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GKQ51_16070	COG0233	cytoplasmic translational termination
GKQ51_16075	COG0528	UMP kinase activity
GKQ51_16080	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GKQ51_16085	COG0052	Belongs to the universal ribosomal protein uS2 family
GKQ51_16090	COG0024	Methionine aminopeptidase
GKQ51_16095	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GKQ51_16100	COG0436	Aminotransferase
GKQ51_16105	COG0025	NhaP-type Na H and K H
GKQ51_16125	COG1393	Belongs to the ArsC family
GKQ51_16130	COG2171	N-acyltransferase activity
GKQ51_16135	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GKQ51_16155	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GKQ51_16160	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GKQ51_16165	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GKQ51_16175	COG2205	protein histidine kinase activity
GKQ51_16180	COG0745	RESPONSE REGULATOR receiver
GKQ51_16185	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GKQ51_16195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GKQ51_16200	COG2226	methyltransferase
GKQ51_16225	COG1131	(ABC) transporter
GKQ51_16235	COG0742	ribosomal rna small subunit methyltransferase
GKQ51_16245	COG1214	PFAM Peptidase M22, glycoprotease
GKQ51_16250	COG0563	adenylate kinase activity
GKQ51_16255	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GKQ51_16275	COG1073	alpha beta
GKQ51_16300	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GKQ51_16315	COG1902	pentaerythritol trinitrate reductase activity
GKQ51_16320	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GKQ51_16335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GKQ51_16355	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GKQ51_16365	COG1607	acyl-coa hydrolase
GKQ51_16370	COG0335	large ribosomal subunit rRNA binding
GKQ51_16375	COG0336	Belongs to the RNA methyltransferase TrmD family
GKQ51_16380	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GKQ51_16385	COG0228	four-way junction DNA binding
GKQ51_16390	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GKQ51_16400	COG4536	flavin adenine dinucleotide binding
GKQ51_16405	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GKQ51_16425	COG1388	LysM domain
GKQ51_16425	COG1376	ErfK ybiS ycfS ynhG family protein
GKQ51_16440	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GKQ51_16445	COG0590	tRNA wobble adenosine to inosine editing
GKQ51_16450	COG2132	Multicopper oxidase
GKQ51_16470	COG0210	DNA helicase
GKQ51_16475	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKQ51_16485	COG1570	exodeoxyribonuclease VII activity
GKQ51_16495	COG0739	heme binding
GKQ51_16550	COG2909	trisaccharide binding
GKQ51_16555	COG0371	Dehydrogenase
GKQ51_16565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GKQ51_16580	COG4993	Dehydrogenase
GKQ51_16600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GKQ51_16605	COG2356	endonuclease I
GKQ51_16610	COG3647	Membrane
GKQ51_16630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GKQ51_16635	COG0436	Aminotransferase
GKQ51_16645	COG1160	GTP binding
GKQ51_16660	COG0124	histidyl-tRNA synthetase
GKQ51_16665	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GKQ51_16685	COG0105	UTP biosynthetic process
GKQ51_16700	COG0443	Heat shock 70 kDa protein
GKQ51_16705	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GKQ51_16710	COG0316	Belongs to the HesB IscA family
GKQ51_16720	COG1104	cysteine desulfurase activity
GKQ51_16760	COG1862	Preprotein translocase
GKQ51_16765	COG0343	queuine tRNA-ribosyltransferase activity
GKQ51_16770	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GKQ51_16780	COG0582	viral genome integration into host DNA
GKQ51_16785	COG0582	viral genome integration into host DNA
GKQ51_16885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GKQ51_16885	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GKQ51_16905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GKQ51_16910	COG4970	Tfp pilus assembly protein FimT
GKQ51_16945	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GKQ51_16950	COG1047	Peptidyl-prolyl cis-trans
GKQ51_16955	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GKQ51_16960	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GKQ51_16965	COG0196	riboflavin kinase activity
GKQ51_16970	COG0728	peptidoglycan biosynthetic process
GKQ51_16975	COG0268	Binds directly to 16S ribosomal RNA
GKQ51_16980	COG3045	CreA protein
GKQ51_16985	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GKQ51_16990	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GKQ51_16995	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GKQ51_17000	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GKQ51_17005	COG0142	geranyltranstransferase activity
GKQ51_17010	COG0545	Peptidyl-prolyl cis-trans isomerase
GKQ51_17015	COG2862	Uncharacterized protein family, UPF0114
GKQ51_17025	COG1067	ATP-dependent peptidase activity
GKQ51_17070	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GKQ51_17075	COG0315	cyclic pyranopterin monophosphate synthase activity
GKQ51_17080	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GKQ51_17090	COG3022	response to hydroperoxide
GKQ51_17105	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GKQ51_17110	COG2010	Cytochrome c
GKQ51_17110	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GKQ51_17120	COG1981	membrane
GKQ51_17130	COG2204	response regulator
GKQ51_17140	COG3685	Protein conserved in bacteria
GKQ51_17145	COG1028	Short-chain dehydrogenase reductase Sdr
GKQ51_17155	COG2323	membrane
GKQ51_17160	COG1271	oxidase subunit
GKQ51_17165	COG1294	oxidase, subunit
GKQ51_17255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GKQ51_17300	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GKQ51_17315	COG3719	Belongs to the RNase T2 family
GKQ51_17320	COG0583	DNA-binding transcription factor activity
GKQ51_17330	COG1024	Enoyl-CoA hydratase
GKQ51_17340	COG1024	Enoyl-CoA hydratase
GKQ51_17345	COG1960	acyl-CoA dehydrogenase activity
GKQ51_17350	COG0583	DNA-binding transcription factor activity
GKQ51_17365	COG0848	biopolymer transport protein
GKQ51_17375	COG2205	protein histidine kinase activity
GKQ51_17380	COG0745	RESPONSE REGULATOR receiver
GKQ51_17420	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GKQ51_17420	COG4651	solute:proton antiporter activity
GKQ51_17435	COG4774	siderophore transport
GKQ51_17470	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GKQ51_17490	COG3052	prosthetic group binding
GKQ51_17495	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
GKQ51_17510	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GKQ51_17525	COG1858	cytochrome C peroxidase
GKQ51_17545	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
GKQ51_17570	COG2267	carboxylic ester hydrolase activity
GKQ51_17595	COG2814	Major facilitator Superfamily
GKQ51_17605	COG1309	transcriptional regulator
GKQ51_17625	COG0123	including yeast histone deacetylase and acetoin utilization protein
GKQ51_17630	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
GKQ51_17650	COG3436	PFAM IS66 Orf2 family protein
GKQ51_17655	COG4372	Transposase
GKQ51_17665	COG0045	succinate-CoA ligase (ADP-forming) activity
GKQ51_17680	COG0513	Belongs to the DEAD box helicase family
GKQ51_17690	COG1643	Atp-dependent helicase
GKQ51_17700	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GKQ51_17705	COG1522	sequence-specific DNA binding
GKQ51_17725	COG4302	ethanolamine ammonia-lyase activity
GKQ51_17730	COG4303	Ethanolamine ammonia lyase large subunit
GKQ51_17735	COG0829	nickel cation binding
GKQ51_17740	COG0831	urea catabolic process
GKQ51_17745	COG0832	Belongs to the urease beta subunit family
GKQ51_17750	COG0804	urea catabolic process
GKQ51_17780	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GKQ51_17785	COG0830	nickel cation binding
GKQ51_17790	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GKQ51_17795	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GKQ51_17805	COG4772	TonB-dependent receptor
GKQ51_17815	COG4264	IucA IucC family
GKQ51_17820	COG2814	Major facilitator Superfamily
GKQ51_17830	COG0019	diaminopimelate decarboxylase activity
GKQ51_17835	COG1960	acyl-CoA dehydrogenase activity
GKQ51_17840	COG0351	phosphomethylpyrimidine kinase
GKQ51_17845	COG0352	thiamine-phosphate diphosphorylase activity
GKQ51_17850	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GKQ51_17875	COG1702	phosphate starvation-inducible protein PhoH
GKQ51_17880	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GKQ51_17890	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GKQ51_17895	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GKQ51_17905	COG0495	leucyl-tRNA aminoacylation
GKQ51_17960	COG4569	acetaldehyde dehydrogenase (acetylating) activity
GKQ51_17990	COG2814	Major facilitator Superfamily
GKQ51_18030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GKQ51_18045	COG2951	lytic endotransglycosylase activity
GKQ51_18060	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GKQ51_18065	COG0321	lipoyl(octanoyl) transferase activity
GKQ51_18070	COG2921	Belongs to the UPF0250 family
GKQ51_18075	COG1686	Belongs to the peptidase S11 family
GKQ51_18085	COG2951	lytic endotransglycosylase activity
GKQ51_18090	COG0772	Belongs to the SEDS family
GKQ51_18095	COG0768	penicillin binding
GKQ51_18100	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GKQ51_18110	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GKQ51_18115	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GKQ51_18120	COG0586	Pfam SNARE associated Golgi protein
GKQ51_18125	COG0366	Alpha amylase catalytic
GKQ51_18135	COG1346	cytolysis
GKQ51_18145	COG0702	epimerase
GKQ51_18185	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GKQ51_18190	COG3284	Transcriptional regulator
GKQ51_18200	COG1454	alcohol dehydrogenase
GKQ51_18210	COG3228	Belongs to the MtfA family
GKQ51_18225	COG5001	Diguanylate cyclase
GKQ51_18225	COG3300	MHYT domain
GKQ51_18230	COG1722	exodeoxyribonuclease VII activity
GKQ51_18235	COG0142	geranyltranstransferase activity
GKQ51_18240	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GKQ51_18255	COG2252	PERMEase
GKQ51_18260	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GKQ51_18275	COG2321	neutral zinc metallopeptidase
GKQ51_18285	COG1946	Acyl-CoA thioesterase
GKQ51_18295	COG2813	Specifically methylates the guanine in position
GKQ51_18325	COG0305	Participates in initiation and elongation during chromosome replication
GKQ51_18330	COG0359	binds to the 23S rRNA
GKQ51_18340	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GKQ51_18345	COG0360	Binds together with S18 to 16S ribosomal RNA
GKQ51_18355	COG0557	exoribonuclease II activity
GKQ51_18370	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GKQ51_18375	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GKQ51_18385	COG0330	HflC and HflK could
GKQ51_18390	COG0330	HflC and HflK could
GKQ51_18395	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GKQ51_18400	COG1923	regulation of RNA biosynthetic process
GKQ51_18405	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GKQ51_18410	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GKQ51_18415	COG0860	N-Acetylmuramoyl-L-alanine amidase
GKQ51_18420	COG0802	atpase or kinase
GKQ51_18425	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GKQ51_18425	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GKQ51_18435	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GKQ51_18440	COG1162	GTPase activity
GKQ51_18450	COG0688	phosphatidylethanolamine metabolic process
GKQ51_18455	COG5002	protein histidine kinase activity
GKQ51_18455	COG5001	Diguanylate cyclase
GKQ51_18460	COG1063	alcohol dehydrogenase
GKQ51_18475	COG3766	membrane
GKQ51_18480	COG5463	Belongs to the UPF0441 family
GKQ51_18485	COG0754	glutathionylspermidine amidase activity
GKQ51_18510	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GKQ51_18515	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
GKQ51_18525	COG0765	amino acid transport
GKQ51_18530	COG0765	amino acid transport
GKQ51_18535	COG1126	abc transporter atp-binding protein
GKQ51_18550	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GKQ51_18605	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GKQ51_18620	COG4178	(ABC) transporter
GKQ51_18630	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GKQ51_18640	COG1053	succinate dehydrogenase
GKQ51_18655	COG0589	response to stress
GKQ51_18665	COG0534	Mate efflux family protein
GKQ51_18670	COG1166	arginine decarboxylase activity
GKQ51_18675	COG0023	Translation Initiation Factor
GKQ51_18695	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKQ51_18715	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GKQ51_18730	COG2264	protein methyltransferase activity
GKQ51_18750	COG0138	bifunctional purine biosynthesis protein purh
GKQ51_18765	COG0443	Heat shock 70 kDa protein
GKQ51_18775	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GKQ51_18790	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GKQ51_18800	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GKQ51_18805	COG3577	Aspartyl protease
GKQ51_18815	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GKQ51_18830	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GKQ51_18845	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GKQ51_18845	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GKQ51_18850	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GKQ51_18860	COG2264	protein methyltransferase activity
GKQ51_18865	COG3118	belongs to the thioredoxin family
GKQ51_18880	COG4181	ATPase activity
GKQ51_18905	COG0848	biopolymer transport protein
GKQ51_18910	COG0811	peptide transport
GKQ51_18915	COG0811	peptide transport
GKQ51_18925	COG3047	cAMP biosynthetic process
GKQ51_18930	COG3047	cAMP biosynthetic process
GKQ51_18935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GKQ51_18945	COG1028	Short-chain dehydrogenase reductase Sdr
GKQ51_18960	COG2814	Major facilitator Superfamily
GKQ51_18970	COG0203	ribosomal protein L17
GKQ51_18975	COG0202	RNA polymerase activity
GKQ51_18980	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GKQ51_18990	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GKQ51_18995	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GKQ51_19005	COG0200	Binds to the 23S rRNA
GKQ51_19015	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GKQ51_19025	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GKQ51_19035	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GKQ51_19045	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GKQ51_19050	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GKQ51_19055	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GKQ51_19060	COG0255	Belongs to the universal ribosomal protein uL29 family
GKQ51_19065	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GKQ51_19070	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GKQ51_19075	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GKQ51_19080	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GKQ51_19085	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GKQ51_19090	COG0089	rRNA binding
GKQ51_19095	COG0088	Forms part of the polypeptide exit tunnel
GKQ51_19100	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GKQ51_19105	COG0051	transcription antitermination factor activity, RNA binding
GKQ51_19120	COG0049	tRNA binding
GKQ51_19125	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GKQ51_19130	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKQ51_19135	COG0085	RNA polymerase activity
GKQ51_19140	COG0222	ribosome binding
GKQ51_19145	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GKQ51_19150	COG0081	regulation of translation
GKQ51_19155	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GKQ51_19200	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GKQ51_19205	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GKQ51_19205	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GKQ51_19215	COG1289	transmembrane transporter activity
GKQ51_19230	COG2354	Protein conserved in bacteria
GKQ51_19240	COG1451	nucleotide metabolic process
GKQ51_19250	COG0126	phosphoglycerate kinase activity
GKQ51_19265	COG2226	methyltransferase
GKQ51_19270	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GKQ51_19285	COG0494	nUDIX hydrolase
GKQ51_19290	COG1011	Hydrolase
GKQ51_19325	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GKQ51_19340	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GKQ51_19390	COG1215	transferase activity, transferring glycosyl groups
GKQ51_19395	COG0726	polysaccharide deacetylase
GKQ51_19430	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GKQ51_19435	COG4067	protein conserved in archaea
GKQ51_19435	COG0189	ligase activity
GKQ51_19440	COG0189	ligase activity
GKQ51_19470	COG0457	Tetratricopeptide repeat
GKQ51_19480	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GKQ51_19490	COG2183	response to ionizing radiation
GKQ51_19500	COG2918	glutathione biosynthetic process
GKQ51_19505	COG0366	Alpha amylase catalytic
GKQ51_19505	COG5263	repeat protein
GKQ51_19535	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GKQ51_19540	COG1459	type II secretion system
GKQ51_19560	COG4795	General secretion pathway protein
GKQ51_19565	COG3156	type II secretion system protein K
GKQ51_19580	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GKQ51_19580	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GKQ51_19590	COG0306	phosphate transporter
GKQ51_19595	COG1392	Phosphate transport regulator
GKQ51_19600	COG3025	triphosphatase activity
GKQ51_19610	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GKQ51_19625	COG3132	Protein of unknown function, DUF480
GKQ51_19630	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GKQ51_19635	COG1127	ABC transporter
GKQ51_19640	COG3218	ABC-type transport auxiliary lipoprotein component
GKQ51_19640	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GKQ51_19660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GKQ51_19665	COG0583	DNA-binding transcription factor activity
GKQ51_19675	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GKQ51_19680	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GKQ51_19700	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GKQ51_19705	COG4942	peptidase
GKQ51_19710	COG0793	Belongs to the peptidase S41A family
GKQ51_19715	COG0107	imidazoleglycerol-phosphate synthase activity
GKQ51_19720	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GKQ51_19725	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GKQ51_19730	COG0131	Imidazoleglycerol-phosphate dehydratase
GKQ51_19745	COG1194	a g-specific adenine glycosylase
GKQ51_19750	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GKQ51_19780	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GKQ51_19780	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GKQ51_19795	COG1178	ABC-type Fe3 transport system permease component
GKQ51_19805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GKQ51_19810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GKQ51_19815	COG0006	proline dipeptidase activity
GKQ51_19820	COG3079	Belongs to the UPF0149 family
GKQ51_19840	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GKQ51_19855	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GKQ51_19870	COG0248	Ppx GppA phosphatase
GKQ51_19875	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GKQ51_19885	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GKQ51_19890	COG1671	Belongs to the UPF0178 family
GKQ51_19895	COG0672	)-iron permease
GKQ51_19900	COG1280	lysine exporter protein (LysE YggA)
GKQ51_19905	COG0861	Integral membrane protein TerC family
GKQ51_19910	COG0488	(ABC) transporter
GKQ51_19960	COG0165	Argininosuccinate lyase
GKQ51_19965	COG0598	Magnesium transport protein CorA
GKQ51_19980	COG1965	Belongs to the frataxin family
GKQ51_19995	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GKQ51_20005	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GKQ51_20025	COG0432	Pfam Uncharacterised protein family UPF0047
GKQ51_20030	COG0004	ammonium transporteR
GKQ51_20035	COG0347	Belongs to the P(II) protein family
GKQ51_20045	COG0606	chelatase, subunit chli
GKQ51_20060	COG0583	DNA-binding transcription factor activity
GKQ51_20070	COG1741	Belongs to the pirin family
GKQ51_20090	COG0753	catalase activity
GKQ51_20095	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GKQ51_20115	COG0251	oxidation-reduction process
GKQ51_20120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GKQ51_20130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GKQ51_20135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKQ51_20145	COG1012	belongs to the aldehyde dehydrogenase family
GKQ51_20150	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GKQ51_20155	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GKQ51_20160	COG0235	Class ii aldolase
GKQ51_20170	COG0747	negative chemotaxis
GKQ51_20180	COG2177	Part of the ABC transporter FtsEX involved in
GKQ51_20185	COG2884	Cell division ATP-binding protein ftsE
GKQ51_20190	COG0552	protein localization to endoplasmic reticulum
GKQ51_20200	COG3039	Transposase
GKQ51_20215	COG0612	Peptidase, M16
GKQ51_20220	COG0612	Peptidase, M16
GKQ51_20225	COG0742	ribosomal rna small subunit methyltransferase
GKQ51_20230	COG0429	hydrolase of the alpha beta-hydrolase fold
GKQ51_20235	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GKQ51_20245	COG0582	viral genome integration into host DNA
GKQ51_20345	COG1396	sequence-specific DNA binding
GKQ51_20455	COG0583	DNA-binding transcription factor activity
GKQ51_20515	COG2864	formate dehydrogenase
GKQ51_20520	COG0437	4 iron, 4 sulfur cluster binding
GKQ51_20525	COG3383	formate dehydrogenase (NAD+) activity
GKQ51_20525	COG0243	molybdopterin cofactor binding
GKQ51_20530	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GKQ51_20535	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GKQ51_20590	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GKQ51_20605	COG0738	Major facilitator superfamily
GKQ51_20610	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKQ51_20615	COG2721	sulfolactate sulfo-lyase activity
GKQ51_20620	COG2271	Major facilitator Superfamily
GKQ51_20625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GKQ51_20630	COG2186	Transcriptional regulator
GKQ51_20635	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GKQ51_20650	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GKQ51_20655	COG0513	Belongs to the DEAD box helicase family
GKQ51_20665	COG2353	YceI-like domain
GKQ51_20670	COG3038	cytochrome b561
GKQ51_20685	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GKQ51_20710	COG0784	Response regulator, receiver
GKQ51_20710	COG0643	Histidine kinase
GKQ51_20710	COG2198	Histidine kinase
GKQ51_20715	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GKQ51_20755	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GKQ51_20765	COG0540	Belongs to the ATCase OTCase family
GKQ51_20805	COG1872	DUF167
GKQ51_20810	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GKQ51_20815	COG2813	Specifically methylates the guanine in position
GKQ51_20815	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GKQ51_20830	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GKQ51_20835	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GKQ51_20840	COG2022	thiamine diphosphate biosynthetic process
GKQ51_20850	COG2363	Small membrane protein
GKQ51_20855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GKQ51_20860	COG2003	Belongs to the UPF0758 family
GKQ51_20865	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GKQ51_20870	COG0756	dUTP diphosphatase activity
GKQ51_20880	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GKQ51_20890	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GKQ51_20895	COG0708	Exodeoxyribonuclease III
GKQ51_20905	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GKQ51_20910	COG1561	YicC-like family, N-terminal region
GKQ51_20925	COG1758	RNA polymerase activity
GKQ51_20930	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GKQ51_20980	COG1120	ATPase activity
GKQ51_20985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GKQ51_21005	COG3486	L-lysine 6-monooxygenase (NADPH) activity
GKQ51_21015	COG4774	siderophore transport
GKQ51_21035	COG4615	Cyclic peptide transporter
GKQ51_21175	COG3842	ATPase activity
GKQ51_21190	COG4149	molybdate abc transporter
GKQ51_21210	COG2914	Belongs to the UPF0125 (RnfH) family
GKQ51_21215	COG4660	Part of a membrane complex involved in electron transport
GKQ51_21230	COG4656	Part of a membrane complex involved in electron transport
GKQ51_21235	COG2878	Part of a membrane complex involved in electron transport
GKQ51_21240	COG4657	Part of a membrane complex involved in electron transport
GKQ51_21280	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GKQ51_21285	COG3604	Transcriptional regulator
GKQ51_21295	COG2116	formate transmembrane transporter activity
GKQ51_21300	COG2271	Major facilitator Superfamily
GKQ51_21305	COG0450	alkyl hydroperoxide reductase
GKQ51_21340	COG1538	Outer membrane efflux protein
GKQ51_21345	COG1250	3-hydroxyacyl-CoA dehydrogenase
GKQ51_21355	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GKQ51_21380	COG0840	transmembrane signaling receptor activity
GKQ51_21400	COG0754	glutathionylspermidine amidase activity
GKQ51_21410	COG3766	membrane
GKQ51_21445	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GKQ51_21450	COG1074	ATP-dependent DNA helicase activity
GKQ51_21455	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GKQ51_21470	COG1272	protein, Hemolysin III
GKQ51_21475	COG1082	Xylose isomerase domain protein TIM barrel
GKQ51_21495	COG0366	Alpha amylase catalytic
GKQ51_21565	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GKQ51_21570	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GKQ51_21585	COG2995	paraquat-inducible protein a
GKQ51_21590	COG2995	paraquat-inducible protein a
GKQ51_21595	COG3008	intermembrane lipid transfer
GKQ51_21595	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GKQ51_21605	COG0628	permease
GKQ51_21610	COG0318	PFAM AMP-dependent synthetase and ligase
GKQ51_21630	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GKQ51_21635	COG1349	DNA-binding transcription factor activity
GKQ51_21645	COG3012	SEC-C Motif Domain Protein
GKQ51_21650	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GKQ51_21670	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GKQ51_21680	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GKQ51_21710	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GKQ51_21715	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GKQ51_21720	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GKQ51_21725	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GKQ51_21730	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GKQ51_21735	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GKQ51_21745	COG0356	it plays a direct role in the translocation of protons across the membrane
GKQ51_21755	COG1475	DNA binding
GKQ51_21760	COG1192	Involved in chromosome partitioning
GKQ51_21765	COG0357	Ribosomal RNA small subunit methyltransferase G
GKQ51_21770	COG0445	tRNA wobble uridine modification
GKQ51_21780	COG0706	membrane insertase activity
GKQ51_21785	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GKQ51_21790	COG0594	ribonuclease P activity
GKQ51_21795	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GKQ51_21920	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKQ51_21965	COG4453	Protein conserved in bacteria
GKQ51_21970	COG0583	DNA-binding transcription factor activity
GKQ51_21980	COG2814	Major facilitator Superfamily
GKQ51_21995	COG1228	amidohydrolase
GKQ51_22000	COG4297	protein containing double-stranded beta helix domain
GKQ51_22005	COG2084	Dehydrogenase
GKQ51_22055	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GKQ51_22100	COG1609	Transcriptional regulator
GKQ51_22105	COG4771	TonB-dependent receptor
GKQ51_22110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GKQ51_22115	COG0667	Aldo Keto reductase
GKQ51_22120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GKQ51_22225	COG0248	Ppx GppA phosphatase
GKQ51_22230	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GKQ51_22295	COG1028	Short-chain dehydrogenase reductase Sdr
GKQ51_22300	COG2814	Major facilitator Superfamily
GKQ51_22310	COG1028	Short-chain dehydrogenase reductase Sdr
GKQ51_22330	COG2826	transposase and inactivated derivatives, IS30 family
GKQ51_22350	COG1335	isochorismatase
GKQ51_22380	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GKQ51_22385	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GKQ51_22440	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
GKQ51_22440	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
GKQ51_22465	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GKQ51_22495	COG1902	pentaerythritol trinitrate reductase activity
GKQ51_22510	COG1028	Short-chain dehydrogenase reductase Sdr
GKQ51_22520	COG0583	DNA-binding transcription factor activity
GKQ51_22590	COG0675	Transposase, IS605 OrfB family
GKQ51_22625	COG1335	isochorismatase
GKQ51_22635	COG0667	Aldo Keto reductase
GKQ51_22670	COG2814	Major facilitator Superfamily
GKQ51_22675	COG1902	pentaerythritol trinitrate reductase activity
GKQ51_22685	COG0583	DNA-binding transcription factor activity
GKQ51_22710	COG1028	Short-chain dehydrogenase reductase Sdr
GKQ51_22720	COG0583	DNA-binding transcription factor activity
GKQ51_22745	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GKQ51_22775	COG5642	Protein of unknown function (DUF2384)
GKQ51_22780	COG5654	RES domain protein
GKQ51_22795	COG0583	DNA-binding transcription factor activity
GKQ51_22800	COG1028	Short-chain dehydrogenase reductase Sdr
GKQ51_22840	COG2304	oxidoreductase activity
GKQ51_22845	COG1595	DNA-templated transcription, initiation
GKQ51_22875	COG0582	viral genome integration into host DNA
GKQ51_22890	COG4372	Transposase
GKQ51_22895	COG3436	PFAM IS66 Orf2 family protein
GKQ51_22920	COG2274	protein secretion by the type I secretion system
GKQ51_22975	COG3077	Addiction module antitoxin, RelB DinJ family
GKQ51_23000	COG2814	Major facilitator Superfamily
GKQ51_23005	COG1028	Short-chain dehydrogenase reductase Sdr
GKQ51_23015	COG4702	Belongs to the UPF0303 family
GKQ51_23020	COG0673	inositol 2-dehydrogenase activity
GKQ51_23025	COG1349	DNA-binding transcription factor activity
GKQ51_23035	COG2207	Transcriptional regulator
GKQ51_23055	COG1028	Short-chain dehydrogenase reductase Sdr
GKQ51_23065	COG1028	Short-chain dehydrogenase reductase Sdr
GKQ51_23070	COG1741	Belongs to the pirin family
GKQ51_23075	COG0583	DNA-binding transcription factor activity
GKQ51_23080	COG0655	NAD(P)H dehydrogenase (quinone) activity
GKQ51_23110	COG4221	oxidoreductase activity
GKQ51_23145	COG3039	Transposase
GKQ51_23160	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GKQ51_23185	COG1741	Belongs to the pirin family
GKQ51_23195	COG0604	alcohol dehydrogenase
GKQ51_23230	COG1120	ATPase activity
GKQ51_23245	COG1475	DNA binding
GKQ51_23250	COG1192	Involved in chromosome partitioning
GKQ51_23280	COG0675	Transposase, IS605 OrfB family
GKQ51_23315	COG0210	DNA helicase
GKQ51_23330	COG1741	Belongs to the pirin family
GKQ51_23355	COG1741	Belongs to the pirin family
GKQ51_23490	COG2944	sequence-specific DNA binding
GKQ51_23515	COG4974	Belongs to the 'phage' integrase family
GKQ51_23570	COG3039	Transposase
GKQ51_23605	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GKQ51_23615	COG0732	type I restriction modification DNA specificity domain
GKQ51_23630	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GKQ51_23710	COG1569	PIN domain
GKQ51_23715	COG3311	Transcriptional regulator
GKQ51_23725	COG2944	sequence-specific DNA binding
GKQ51_23740	COG2184	nucleotidyltransferase activity
GKQ51_23810	COG0039	L-malate dehydrogenase activity
GKQ51_23820	COG1741	Belongs to the pirin family
GKQ51_23830	COG4974	Belongs to the 'phage' integrase family
GKQ51_23845	COG3039	Transposase
GKQ51_23860	COG2814	Major facilitator Superfamily
GKQ51_23865	COG0179	Fumarylacetoacetate (FAA) hydrolase
GKQ51_23875	COG1012	belongs to the aldehyde dehydrogenase family
GKQ51_23880	COG3384	dioxygenase
GKQ51_23890	COG2271	Major facilitator Superfamily
GKQ51_23895	COG3971	2-oxopent-4-enoate hydratase activity
GKQ51_23905	COG1012	belongs to the aldehyde dehydrogenase family
GKQ51_23910	COG1846	Transcriptional regulator
GKQ51_23930	COG1960	acyl-CoA dehydrogenase activity
GKQ51_23935	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GKQ51_23945	COG3436	PFAM IS66 Orf2 family protein
GKQ51_23950	COG4372	Transposase
GKQ51_23970	COG0489	protein tyrosine kinase activity
GKQ51_24010	COG2337	Toxic component of a toxin-antitoxin (TA) module