locus-tag	class	description
Avin_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Avin_00030	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Avin_00060	COG2837	iron assimilation
Avin_00090	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Avin_00100	COG0751	glycine-tRNA ligase activity
Avin_00120	COG2818	Glycosylase
Avin_00130	COG0737	Belongs to the 5'-nucleotidase family
Avin_00130	COG4085	toxin activity
Avin_00130	COG1525	nuclease
Avin_00140	COG0569	domain protein
Avin_00150	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Avin_00170	COG0242	peptide deformylase activity
Avin_00190	COG0758	DNA mediated transformation
Avin_00200	COG0009	L-threonylcarbamoyladenylate synthase
Avin_00220	COG0408	coproporphyrinogen oxidase activity
Avin_00230	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Avin_00250	COG2132	Multicopper oxidase
Avin_00280	COG1285	pathogenesis
Avin_00370	COG0745	RESPONSE REGULATOR receiver
Avin_00370	COG3706	GGDEF domain
Avin_00380	COG0655	NAD(P)H dehydrogenase (quinone) activity
Avin_00390	COG0700	Nucleoside recognition
Avin_00420	COG3706	GGDEF domain
Avin_00520	COG0210	DNA helicase
Avin_00580	COG0842	Transport permease protein
Avin_00590	COG0842	Transport permease protein
Avin_00600	COG1131	(ABC) transporter
Avin_00620	COG1309	transcriptional regulator
Avin_00660	COG2945	thiolester hydrolase activity
Avin_00660	COG0596	Alpha beta hydrolase
Avin_00720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Avin_00750	COG0675	Transposase, IS605 OrfB family
Avin_00790	COG1335	isochorismatase
Avin_00820	COG1305	Transglutaminase-like
Avin_00830	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
Avin_00840	COG0735	belongs to the Fur family
Avin_00850	COG1121	(ABC) transporter
Avin_00860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Avin_00940	COG0109	protoheme IX farnesyltransferase activity
Avin_00950	COG1612	heme a metabolic process
Avin_01000	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
Avin_01010	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Avin_01050	COG0659	secondary active sulfate transmembrane transporter activity
Avin_01110	COG3712	iron ion homeostasis
Avin_01130	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Avin_01180	COG0252	asparaginase activity
Avin_01220	COG1686	Belongs to the peptidase S11 family
Avin_01280	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
Avin_01330	COG2814	Major facilitator Superfamily
Avin_01340	COG0204	Acyl-transferase
Avin_01340	COG0318	PFAM AMP-dependent synthetase and ligase
Avin_01520	COG3411	Ferredoxin
Avin_01740	COG0523	cobalamin synthesis protein
Avin_01760	COG1607	acyl-coa hydrolase
Avin_01780	COG1283	sodium-dependent phosphate transmembrane transporter activity
Avin_01800	COG1764	response to oxidative stress
Avin_01840	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Avin_01850	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Avin_01860	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Avin_01880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Avin_01970	COG3023	N-Acetylmuramoyl-L-alanine amidase
Avin_02010	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Avin_02020	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Avin_02040	COG0583	DNA-binding transcription factor activity
Avin_02050	COG0439	Biotin carboxylase
Avin_02060	COG0511	ligase activity, forming carbon-carbon bonds
Avin_02060	COG5016	pyruvate
Avin_02070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Avin_02120	COG0133	tryptophan synthase activity
Avin_02130	COG0159	tryptophan synthase activity
Avin_02190	COG0484	heat shock protein binding
Avin_02200	COG0789	Transcriptional regulator
Avin_02210	COG0730	response to heat
Avin_02250	COG1595	DNA-templated transcription, initiation
Avin_02310	COG2356	endonuclease I
Avin_02330	COG3237	CsbD-like
Avin_02350	COG0789	Transcriptional regulator
Avin_02380	COG2982	Protein involved in outer membrane biogenesis
Avin_02400	COG0778	Nitroreductase
Avin_02410	COG1136	(ABC) transporter
Avin_02410	COG0577	efflux transmembrane transporter activity
Avin_02470	COG0366	Alpha amylase catalytic
Avin_02510	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Avin_02520	COG2841	Protein conserved in bacteria
Avin_02550	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
Avin_02560	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Avin_02710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Avin_02810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Avin_02820	COG1758	RNA polymerase activity
Avin_02840	COG1561	YicC-like family, N-terminal region
Avin_02850	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Avin_02870	COG0708	Exodeoxyribonuclease III
Avin_02880	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Avin_02900	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Avin_02920	COG0756	dUTP diphosphatase activity
Avin_02930	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Avin_02940	COG2003	Belongs to the UPF0758 family
Avin_02950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Avin_02960	COG2363	Small membrane protein
Avin_02980	COG2022	thiamine diphosphate biosynthetic process
Avin_02990	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Avin_03000	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Avin_03030	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Avin_03030	COG2813	Specifically methylates the guanine in position
Avin_03040	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Avin_03050	COG1872	DUF167
Avin_03120	COG0540	Belongs to the ATCase OTCase family
Avin_03140	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Avin_03190	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Avin_03240	COG3038	cytochrome b561
Avin_03250	COG2353	YceI-like domain
Avin_03280	COG2205	protein histidine kinase activity
Avin_03310	COG0129	dihydroxy-acid dehydratase activity
Avin_03350	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Avin_03360	COG0842	Transport permease protein
Avin_03370	COG1131	(ABC) transporter
Avin_03380	COG0840	transmembrane signaling receptor activity
Avin_03390	COG0693	protein deglycase activity
Avin_03400	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Avin_03450	COG0247	lactate metabolic process
Avin_03470	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Avin_03490	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Avin_03500	COG0429	hydrolase of the alpha beta-hydrolase fold
Avin_03510	COG0742	ribosomal rna small subunit methyltransferase
Avin_03520	COG0612	Peptidase, M16
Avin_03530	COG0612	Peptidase, M16
Avin_03540	COG0513	Belongs to the DEAD box helicase family
Avin_03550	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Avin_03590	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Avin_03600	COG0738	Major facilitator superfamily
Avin_03620	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Avin_03760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Avin_03770	COG2814	Major facilitator Superfamily
Avin_03780	COG1902	pentaerythritol trinitrate reductase activity
Avin_03790	COG0583	DNA-binding transcription factor activity
Avin_03800	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Avin_03810	COG0243	molybdopterin cofactor binding
Avin_03810	COG3383	formate dehydrogenase (NAD+) activity
Avin_03820	COG0437	4 iron, 4 sulfur cluster binding
Avin_03830	COG2864	formate dehydrogenase
Avin_03870	COG1595	DNA-templated transcription, initiation
Avin_04020	COG0583	DNA-binding transcription factor activity
Avin_04140	COG0346	lactoylglutathione lyase activity
Avin_04230	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
Avin_04390	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Avin_04430	COG2194	sulfuric ester hydrolase activity
Avin_04490	COG1151	hydroxylamine reductase activity
Avin_04520	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
Avin_04530	COG1194	a g-specific adenine glycosylase
Avin_04570	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Avin_04590	COG0131	Imidazoleglycerol-phosphate dehydratase
Avin_04600	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Avin_04620	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Avin_04630	COG0107	imidazoleglycerol-phosphate synthase activity
Avin_04640	COG0793	Belongs to the peptidase S41A family
Avin_04650	COG4942	peptidase
Avin_04670	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Avin_04700	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
Avin_04710	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Avin_04730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Avin_04760	COG3218	ABC-type transport auxiliary lipoprotein component
Avin_04760	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Avin_04770	COG1127	ABC transporter
Avin_04780	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Avin_04790	COG3132	Protein of unknown function, DUF480
Avin_04840	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Avin_04880	COG0306	phosphate transporter
Avin_04920	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Avin_04920	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Avin_04950	COG5001	Diguanylate cyclase
Avin_04950	COG5002	protein histidine kinase activity
Avin_04950	COG3447	MASE1 domain protein
Avin_05020	COG2918	glutathione biosynthetic process
Avin_05040	COG2183	response to ionizing radiation
Avin_05060	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
Avin_05080	COG0457	Tetratricopeptide repeat
Avin_05120	COG0745	RESPONSE REGULATOR receiver
Avin_05140	COG0189	ligase activity
Avin_05150	COG0189	ligase activity
Avin_05150	COG4067	protein conserved in archaea
Avin_05160	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Avin_05180	COG1012	belongs to the aldehyde dehydrogenase family
Avin_05190	COG2186	Transcriptional regulator
Avin_05220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Avin_05240	COG2271	Major facilitator Superfamily
Avin_05250	COG2721	sulfolactate sulfo-lyase activity
Avin_05260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Avin_05430	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Avin_05480	COG1011	Hydrolase
Avin_05490	COG0494	nUDIX hydrolase
Avin_05500	COG1218	3'(2'),5'-bisphosphate nucleotidase
Avin_05530	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Avin_05540	COG2226	methyltransferase
Avin_05590	COG0126	phosphoglycerate kinase activity
Avin_05610	COG4702	Belongs to the UPF0303 family
Avin_05620	COG0673	inositol 2-dehydrogenase activity
Avin_05630	COG1349	DNA-binding transcription factor activity
Avin_05640	COG1451	nucleotide metabolic process
Avin_05660	COG2354	Protein conserved in bacteria
Avin_05690	COG1289	transmembrane transporter activity
Avin_05740	COG0330	HflC and HflK could
Avin_05750	COG0686	Belongs to the AlaDH PNT family
Avin_05760	COG1309	transcriptional regulator
Avin_05780	COG0625	glutathione transferase activity
Avin_05800	COG2814	Major facilitator Superfamily
Avin_05860	COG0204	Acyl-transferase
Avin_05880	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Avin_05960	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Avin_05970	COG1040	competence protein
Avin_05990	COG0156	8-amino-7-oxononanoate synthase activity
Avin_06000	COG1073	alpha beta
Avin_06000	COG2226	methyltransferase
Avin_06020	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Avin_06040	COG4589	Belongs to the CDS family
Avin_06050	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
Avin_06050	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
Avin_06060	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Avin_06120	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Avin_06130	COG0081	regulation of translation
Avin_06150	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Avin_06160	COG0222	ribosome binding
Avin_06170	COG0085	RNA polymerase activity
Avin_06180	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Avin_06190	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Avin_06200	COG0049	tRNA binding
Avin_06240	COG0051	transcription antitermination factor activity, RNA binding
Avin_06250	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Avin_06260	COG0088	Forms part of the polypeptide exit tunnel
Avin_06270	COG0089	rRNA binding
Avin_06280	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Avin_06290	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Avin_06300	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Avin_06310	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Avin_06320	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Avin_06330	COG0255	Belongs to the universal ribosomal protein uL29 family
Avin_06340	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Avin_06350	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Avin_06360	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Avin_06370	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Avin_06380	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Avin_06390	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Avin_06400	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Avin_06410	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Avin_06420	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Avin_06430	COG1841	ribosomal large subunit assembly
Avin_06440	COG0200	Binds to the 23S rRNA
Avin_06460	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Avin_06470	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Avin_06480	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Avin_06490	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Avin_06500	COG0202	RNA polymerase activity
Avin_06510	COG0203	ribosomal protein L17
Avin_06530	COG2814	Major facilitator Superfamily
Avin_06550	COG0583	DNA-binding transcription factor activity
Avin_06560	COG1028	Short-chain dehydrogenase reductase Sdr
Avin_06580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Avin_06590	COG3047	cAMP biosynthetic process
Avin_06610	COG3047	cAMP biosynthetic process
Avin_06640	COG4181	ATPase activity
Avin_06670	COG3118	belongs to the thioredoxin family
Avin_06680	COG2264	protein methyltransferase activity
Avin_06700	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Avin_06710	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Avin_06710	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Avin_06750	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Avin_06770	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Avin_06780	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Avin_06800	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Avin_06810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Avin_06840	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
Avin_06860	COG0443	Heat shock 70 kDa protein
Avin_06890	COG0138	bifunctional purine biosynthesis protein purh
Avin_06940	COG2264	protein methyltransferase activity
Avin_07010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Avin_07040	COG0023	Translation Initiation Factor
Avin_07050	COG1166	arginine decarboxylase activity
Avin_07070	COG0534	Mate efflux family protein
Avin_07090	COG0589	response to stress
Avin_07120	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Avin_07260	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Avin_07290	COG1126	abc transporter atp-binding protein
Avin_07300	COG0765	amino acid transport
Avin_07310	COG0765	amino acid transport
Avin_07340	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
Avin_07350	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Avin_07410	COG3830	Belongs to the UPF0237 family
Avin_07410	COG0560	Phosphoserine phosphatase
Avin_07420	COG1063	alcohol dehydrogenase
Avin_07440	COG0688	phosphatidylethanolamine metabolic process
Avin_07460	COG1162	GTPase activity
Avin_07470	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
Avin_07490	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Avin_07490	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Avin_07500	COG0802	atpase or kinase
Avin_07510	COG0860	N-Acetylmuramoyl-L-alanine amidase
Avin_07520	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Avin_07530	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Avin_07540	COG1923	regulation of RNA biosynthetic process
Avin_07550	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Avin_07560	COG0330	HflC and HflK could
Avin_07570	COG0330	HflC and HflK could
Avin_07590	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Avin_07600	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Avin_07620	COG0557	exoribonuclease II activity
Avin_07630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Avin_07640	COG0360	Binds together with S18 to 16S ribosomal RNA
Avin_07650	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Avin_07670	COG0359	binds to the 23S rRNA
Avin_07680	COG0305	Participates in initiation and elongation during chromosome replication
Avin_07730	COG2813	Specifically methylates the guanine in position
Avin_07750	COG1946	Acyl-CoA thioesterase
Avin_07760	COG0546	phosphoglycolate phosphatase activity
Avin_07770	COG2321	neutral zinc metallopeptidase
Avin_07800	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Avin_07810	COG2252	PERMEase
Avin_07830	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
Avin_07860	COG4206	TonB-dependent receptor
Avin_07870	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Avin_07880	COG0142	geranyltranstransferase activity
Avin_07890	COG1722	exodeoxyribonuclease VII activity
Avin_07910	COG5001	Diguanylate cyclase
Avin_07910	COG3300	MHYT domain
Avin_07950	COG3228	Belongs to the MtfA family
Avin_07980	COG1454	alcohol dehydrogenase
Avin_08000	COG1012	belongs to the aldehyde dehydrogenase family
Avin_08020	COG3284	Transcriptional regulator
Avin_08030	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Avin_08100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Avin_08130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Avin_08150	COG4771	TonB-dependent receptor
Avin_08170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Avin_08200	COG4771	TonB-dependent receptor
Avin_08240	COG3706	GGDEF domain
Avin_08290	COG0702	epimerase
Avin_08310	COG1346	cytolysis
Avin_08340	COG0586	Pfam SNARE associated Golgi protein
Avin_08350	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Avin_08360	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Avin_08380	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Avin_08390	COG0768	penicillin binding
Avin_08400	COG0772	Belongs to the SEDS family
Avin_08410	COG2951	lytic endotransglycosylase activity
Avin_08430	COG1686	Belongs to the peptidase S11 family
Avin_08440	COG2921	Belongs to the UPF0250 family
Avin_08450	COG0321	lipoyl(octanoyl) transferase activity
Avin_08460	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Avin_08480	COG0028	Belongs to the TPP enzyme family
Avin_08490	COG2951	lytic endotransglycosylase activity
Avin_08530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Avin_08630	COG2814	Major facilitator Superfamily
Avin_08700	COG4569	acetaldehyde dehydrogenase (acetylating) activity
Avin_08740	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Avin_09000	COG0495	leucyl-tRNA aminoacylation
Avin_09020	COG1434	Gram-negative-bacterium-type cell wall biogenesis
Avin_09030	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Avin_09040	COG4535	Mg2 and Co2 transporter CorC
Avin_09050	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Avin_09060	COG1702	phosphate starvation-inducible protein PhoH
Avin_09100	COG3415	Transposase
Avin_09100	COG2801	Transposase and inactivated derivatives
Avin_09140	COG3254	rhamnose metabolic process
Avin_09190	COG4580	involved in the transport of maltose and maltodextrins
Avin_09210	COG2271	Major facilitator Superfamily
Avin_09220	COG4948	Mandelate Racemase Muconate Lactonizing
Avin_09240	COG1012	belongs to the aldehyde dehydrogenase family
Avin_09260	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Avin_09270	COG0352	thiamine-phosphate diphosphorylase activity
Avin_09280	COG0351	phosphomethylpyrimidine kinase
Avin_09290	COG1960	acyl-CoA dehydrogenase activity
Avin_09300	COG0019	diaminopimelate decarboxylase activity
Avin_09320	COG2814	Major facilitator Superfamily
Avin_09330	COG4264	IucA IucC family
Avin_09350	COG4772	TonB-dependent receptor
Avin_09370	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Avin_09380	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Avin_09390	COG0830	nickel cation binding
Avin_09400	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
Avin_09420	COG0673	inositol 2-dehydrogenase activity
Avin_09460	COG1301	dicarboxylic acid transport
Avin_09470	COG0596	Alpha beta hydrolase
Avin_09480	COG0583	DNA-binding transcription factor activity
Avin_09570	COG3293	Transposase
Avin_09640	COG5265	(ABC) transporter
Avin_09724	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Avin_09750	COG2801	Transposase and inactivated derivatives
Avin_09770	COG2963	transposase activity
Avin_09800	COG0066	3-isopropylmalate dehydratase activity
Avin_09810	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Avin_09880	COG0804	urea catabolic process
Avin_09890	COG0832	Belongs to the urease beta subunit family
Avin_09900	COG0831	urea catabolic process
Avin_09910	COG0829	nickel cation binding
Avin_09920	COG4303	Ethanolamine ammonia lyase large subunit
Avin_09930	COG4302	ethanolamine ammonia-lyase activity
Avin_09960	COG1522	sequence-specific DNA binding
Avin_09970	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Avin_09990	COG1643	Atp-dependent helicase
Avin_10010	COG0513	Belongs to the DEAD box helicase family
Avin_10020	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Avin_10020	COG0493	'glutamate synthase
Avin_10030	COG0123	including yeast histone deacetylase and acetoin utilization protein
Avin_10080	COG1309	transcriptional regulator
Avin_10090	COG2814	Major facilitator Superfamily
Avin_10160	COG0628	permease
Avin_10190	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
Avin_10220	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
Avin_10230	COG1858	cytochrome C peroxidase
Avin_10260	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Avin_10290	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
Avin_10300	COG3052	prosthetic group binding
Avin_10340	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Avin_10410	COG1368	sulfuric ester hydrolase activity
Avin_10430	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Avin_10440	COG4774	siderophore transport
Avin_10490	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Avin_10490	COG4651	solute:proton antiporter activity
Avin_10580	COG0745	RESPONSE REGULATOR receiver
Avin_10590	COG2205	protein histidine kinase activity
Avin_10600	COG0306	phosphate transporter
Avin_10620	COG0848	biopolymer transport protein
Avin_10670	COG0583	DNA-binding transcription factor activity
Avin_10680	COG1960	acyl-CoA dehydrogenase activity
Avin_10690	COG1024	Enoyl-CoA hydratase
Avin_10710	COG1024	Enoyl-CoA hydratase
Avin_10730	COG0583	DNA-binding transcription factor activity
Avin_10740	COG3719	Belongs to the RNase T2 family
Avin_10810	COG3223	Belongs to the PsiE family
Avin_10820	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Avin_10830	COG3293	Transposase
Avin_10980	COG5487	UPF0391 membrane protein
Avin_11040	COG1294	oxidase, subunit
Avin_11050	COG1271	oxidase subunit
Avin_11070	COG2323	membrane
Avin_11090	COG1028	Short-chain dehydrogenase reductase Sdr
Avin_11100	COG3685	Protein conserved in bacteria
Avin_11120	COG2204	response regulator
Avin_11180	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Avin_11220	COG3022	response to hydroperoxide
Avin_11240	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Avin_11260	COG0315	cyclic pyranopterin monophosphate synthase activity
Avin_11270	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
Avin_11320	COG2801	Transposase and inactivated derivatives
Avin_11320	COG3415	Transposase
Avin_11350	COG2827	Endonuclease containing a URI domain
Avin_11390	COG0145	ligase activity
Avin_11400	COG4647	ligase activity
Avin_11410	COG0145	ligase activity
Avin_11430	COG0523	cobalamin synthesis protein
Avin_11450	COG3081	Nucleoid-associated protein
Avin_11460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Avin_11490	COG0583	DNA-binding transcription factor activity
Avin_11510	COG1028	Short-chain dehydrogenase reductase Sdr
Avin_11540	COG0420	3'-5' exonuclease activity
Avin_11550	COG0419	ATPase involved in DNA repair
Avin_11570	COG1253	flavin adenine dinucleotide binding
Avin_11590	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
Avin_11650	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Avin_11670	COG0795	lipopolysaccharide-transporting ATPase activity
Avin_11680	COG0795	lipopolysaccharide-transporting ATPase activity
Avin_11760	COG0728	peptidoglycan biosynthetic process
Avin_11770	COG0196	riboflavin kinase activity
Avin_11780	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Avin_11790	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Avin_11800	COG1047	Peptidyl-prolyl cis-trans
Avin_11810	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Avin_11880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Avin_11970	COG1132	(ABC) transporter
Avin_12000	COG1252	NADH dehydrogenase
Avin_12060	COG0237	dephospho-CoA kinase activity
Avin_12070	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Avin_12120	COG3023	N-Acetylmuramoyl-L-alanine amidase
Avin_12140	COG0084	hydrolase, TatD family'
Avin_12180	COG1609	Transcriptional regulator
Avin_12190	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
Avin_12190	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Avin_12200	COG1105	Belongs to the carbohydrate kinase PfkB family
Avin_12210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Avin_12210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Avin_12210	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
Avin_12220	COG1028	Short-chain dehydrogenase reductase Sdr
Avin_12250	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Avin_12270	COG2831	hemolysin activation secretion protein
Avin_12320	COG0019	diaminopimelate decarboxylase activity
Avin_12330	COG4774	siderophore transport
Avin_12340	COG3128	pkhd-type hydroxylase
Avin_12420	COG3128	pkhd-type hydroxylase
Avin_12430	COG4774	siderophore transport
Avin_12460	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Avin_12470	COG1984	allophanate hydrolase subunit 2
Avin_12480	COG4608	Belongs to the ABC transporter superfamily
Avin_12490	COG0444	Belongs to the ABC transporter superfamily
Avin_12500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Avin_12510	COG0601	transmembrane transport
Avin_12520	COG0747	negative chemotaxis
Avin_12560	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
Avin_12600	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Avin_12610	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Avin_12630	COG0154	amidase activity
Avin_12640	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Avin_12650	COG1077	Cell shape determining protein MreB Mrl
Avin_12660	COG1792	Involved in formation and maintenance of cell shape
Avin_12670	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
Avin_12680	COG0424	maF-like protein
Avin_12690	COG1530	ribonuclease E activity
Avin_12710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Avin_12720	COG0312	modulator of DNA gyrase
Avin_12730	COG3028	Belongs to the UPF0307 family
Avin_12740	COG0312	modulator of DNA gyrase
Avin_12760	COG1660	Displays ATPase and GTPase activities
Avin_12800	COG1137	ATPase activity
Avin_12810	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
Avin_12830	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Avin_12850	COG1127	ABC transporter
Avin_12860	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Avin_12870	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Avin_12900	COG5007	Belongs to the BolA IbaG family
Avin_12910	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Avin_12920	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Avin_12930	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Avin_12940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Avin_12950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Avin_12970	COG0175	sulfate reduction
Avin_13020	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Avin_13030	COG1515	deoxyribonuclease V activity
Avin_13040	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Avin_13050	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Avin_13060	COG0723	plastoquinol--plastocyanin reductase activity
Avin_13070	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Avin_13080	COG2857	Cytochrome c1
Avin_13090	COG0625	glutathione transferase activity
Avin_13100	COG2969	positive regulation of protein catabolic process
Avin_13110	COG2823	Periplasmic or secreted lipoprotein
Avin_13120	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Avin_13130	COG0792	nuclease activity
Avin_13160	COG2001	Belongs to the MraZ family
Avin_13170	COG0275	rRNA processing
Avin_13200	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Avin_13210	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Avin_13220	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Avin_13230	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Avin_13240	COG0772	Belongs to the SEDS family
Avin_13250	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Avin_13260	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Avin_13270	COG1181	Belongs to the D-alanine--D-alanine ligase family
Avin_13320	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Avin_13340	COG0653	protein targeting
Avin_13370	COG0494	nUDIX hydrolase
Avin_13380	COG2096	Adenosyltransferase
Avin_13410	COG1666	GTP binding
Avin_13430	COG1028	Short-chain dehydrogenase reductase Sdr
Avin_13440	COG0748	coenzyme F420 binding
Avin_13450	COG3030	protein affecting phage T7 exclusion by the F plasmid
Avin_13470	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Avin_13550	COG1024	Enoyl-CoA hydratase
Avin_13610	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Avin_13720	COG3086	response to oxidative stress
Avin_13730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Avin_13740	COG0481	GTPase activity
Avin_13780	COG0571	ribonuclease III activity
Avin_13790	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Avin_13820	COG1381	Involved in DNA repair and RecF pathway recombination
Avin_13830	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Avin_13850	COG0500	methyltransferase
Avin_13860	COG2226	methyltransferase
Avin_13880	COG1414	Transcriptional regulator
Avin_13900	COG1454	alcohol dehydrogenase
Avin_13910	COG2610	gluconate transmembrane transporter activity
Avin_13920	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Avin_13970	COG0583	DNA-binding transcription factor activity
Avin_14020	COG3842	ATPase activity
Avin_14040	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Avin_14060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Avin_14070	COG0418	dihydroorotase activity
Avin_14080	COG0137	argininosuccinate synthase activity
Avin_14120	COG0521	Mo-molybdopterin cofactor biosynthetic process
Avin_14130	COG0303	'Molybdopterin
Avin_14170	COG0589	response to stress
Avin_14190	COG2814	Major facilitator Superfamily
Avin_14230	COG1024	Enoyl-CoA hydratase
Avin_14240	COG1012	belongs to the aldehyde dehydrogenase family
Avin_14250	COG3320	Male sterility
Avin_14250	COG1022	Amp-dependent synthetase and ligase
Avin_14270	COG1960	acyl-CoA dehydrogenase activity
Avin_14310	COG0745	RESPONSE REGULATOR receiver
Avin_14320	COG2205	protein histidine kinase activity
Avin_14330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Avin_14340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Avin_14440	COG1250	3-hydroxyacyl-CoA dehydrogenase
Avin_14440	COG1024	Enoyl-CoA hydratase
Avin_14450	COG0183	Belongs to the thiolase family
Avin_14510	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Avin_14550	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Avin_14570	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Avin_14600	COG1805	sodium ion transport
Avin_14630	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Avin_14650	COG1477	protein flavinylation
Avin_14670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Avin_14680	COG0584	glycerophosphoryl diester phosphodiesterase
Avin_14700	COG1136	(ABC) transporter
Avin_14710	COG4591	ABC-type transport system involved in lipoprotein release permease component
Avin_14730	COG0658	competence protein
Avin_14730	COG2333	competence protein COMEC
Avin_14740	COG0811	peptide transport
Avin_14750	COG0848	biopolymer transport protein
Avin_14760	COG1663	tetraacyldisaccharide 4'-kinase activity
Avin_14770	COG2835	tetraacyldisaccharide 4'-kinase activity
Avin_14790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Avin_14800	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Avin_14810	COG1530	ribonuclease E activity
Avin_14840	COG0546	phosphoglycolate phosphatase activity
Avin_14850	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Avin_14850	COG0616	signal peptide processing
Avin_14860	COG0424	maF-like protein
Avin_14880	COG1399	metal-binding, possibly nucleic acid-binding protein
Avin_14890	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Avin_14900	COG0416	fatty acid biosynthetic process
Avin_14930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Avin_14940	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Avin_14960	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Avin_15000	COG0084	hydrolase, TatD family'
Avin_15020	COG3293	Transposase
Avin_15030	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Avin_15050	COG1355	regulation of microtubule-based process
Avin_15060	COG1960	acyl-CoA dehydrogenase activity
Avin_15070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Avin_15080	COG2267	carboxylic ester hydrolase activity
Avin_15090	COG1414	Transcriptional regulator
Avin_15110	COG3971	2-oxopent-4-enoate hydratase activity
Avin_15120	COG4569	acetaldehyde dehydrogenase (acetylating) activity
Avin_15130	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Avin_15140	COG2814	Major facilitator Superfamily
Avin_15280	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Avin_15290	COG1764	response to oxidative stress
Avin_15300	COG1846	Transcriptional regulator
Avin_15310	COG0583	DNA-binding transcription factor activity
Avin_15320	COG0730	response to heat
Avin_15350	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
Avin_15380	COG0500	methyltransferase
Avin_15400	COG0501	Belongs to the peptidase M48B family
Avin_15420	COG0436	Aminotransferase
Avin_15440	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Avin_15450	COG0386	Belongs to the glutathione peroxidase family
Avin_15460	COG2205	protein histidine kinase activity
Avin_15460	COG3437	response regulator, receiver
Avin_15460	COG3850	Histidine kinase
Avin_15460	COG4999	Histidine kinase
Avin_15490	COG1960	acyl-CoA dehydrogenase activity
Avin_15500	COG1131	(ABC) transporter
Avin_15510	COG0842	Transport permease protein
Avin_15540	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Avin_15540	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Avin_15550	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Avin_15580	COG0778	Nitroreductase
Avin_15590	COG0642	Histidine kinase
Avin_15610	COG0745	RESPONSE REGULATOR receiver
Avin_15620	COG2350	Protein conserved in bacteria
Avin_15630	COG2917	probably involved in intracellular septation
Avin_15640	COG0613	PHP domain protein
Avin_15650	COG0009	L-threonylcarbamoyladenylate synthase
Avin_15660	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Avin_15670	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Avin_15720	COG0800	Aldolase
Avin_15740	COG1028	Short-chain dehydrogenase reductase Sdr
Avin_15750	COG0546	phosphoglycolate phosphatase activity
Avin_15760	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Avin_15770	COG0402	S-adenosylhomocysteine deaminase activity
Avin_15780	COG0675	Transposase, IS605 OrfB family
Avin_15790	COG3415	Transposase
Avin_15790	COG2801	Transposase and inactivated derivatives
Avin_15800	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Avin_15820	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Avin_15850	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Avin_15860	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Avin_15880	COG0776	regulation of translation
Avin_15900	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Avin_15920	COG1088	dTDP-glucose 4,6-dehydratase activity
Avin_15960	COG1682	transport, permease protein
Avin_15980	COG1216	Glycosyl transferase, family 2
Avin_15980	COG0438	transferase activity, transferring glycosyl groups
Avin_16070	COG1450	Type ii and iii secretion system protein
Avin_16160	COG1459	type II secretion system
Avin_16170	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Avin_16230	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Avin_16250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Avin_16270	COG1643	Atp-dependent helicase
Avin_16280	COG2161	toxin-antitoxin pair type II binding
Avin_16360	COG2814	Major facilitator Superfamily
Avin_16380	COG0183	Belongs to the thiolase family
Avin_16390	COG1024	Enoyl-CoA hydratase
Avin_16390	COG1250	3-hydroxyacyl-CoA dehydrogenase
Avin_16400	COG1960	acyl-CoA dehydrogenase activity
Avin_16440	COG0427	acetyl-CoA hydrolase
Avin_16450	COG2801	Transposase and inactivated derivatives
Avin_16490	COG1028	Short-chain dehydrogenase reductase Sdr
Avin_16540	COG2963	transposase activity
Avin_16550	COG2801	Transposase and inactivated derivatives
Avin_16590	COG1063	alcohol dehydrogenase
Avin_16630	COG0166	Belongs to the GPI family
Avin_16650	COG4580	involved in the transport of maltose and maltodextrins
Avin_16680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Avin_16690	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Avin_16700	COG0427	acetyl-CoA hydrolase
Avin_16720	COG0583	DNA-binding transcription factor activity
Avin_16730	COG1028	Short-chain dehydrogenase reductase Sdr
Avin_16770	COG0842	Transport permease protein
Avin_16780	COG0842	Transport permease protein
Avin_16780	COG1129	ABC transporter
Avin_16790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Avin_16800	COG0675	Transposase, IS605 OrfB family
Avin_16810	COG0167	dihydroorotate dehydrogenase activity
Avin_16870	COG4221	oxidoreductase activity
Avin_16890	COG2133	pyrroloquinoline quinone binding
Avin_17090	COG0583	DNA-binding transcription factor activity
Avin_17120	COG2851	Citrate transporter
Avin_17200	COG1857	crispr-associated protein
Avin_17250	COG4680	protein conserved in bacteria
Avin_17290	COG0438	transferase activity, transferring glycosyl groups
Avin_17300	COG2814	Major facilitator Superfamily
Avin_17330	COG2197	response regulator
Avin_17340	COG4585	Histidine kinase
Avin_17350	COG1024	Enoyl-CoA hydratase
Avin_17350	COG1250	3-hydroxyacyl-CoA dehydrogenase
Avin_17360	COG0183	Belongs to the thiolase family
Avin_17370	COG0318	PFAM AMP-dependent synthetase and ligase
Avin_17380	COG1960	acyl-CoA dehydrogenase activity
Avin_17420	COG0003	Pfam Anion-transporting ATPase
Avin_17440	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Avin_17510	COG3639	organic phosphonate transmembrane transporter activity
Avin_17520	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Avin_17550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Avin_17560	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Avin_17590	COG1028	Short-chain dehydrogenase reductase Sdr
Avin_17600	COG2610	gluconate transmembrane transporter activity
Avin_17610	COG3604	Transcriptional regulator
Avin_17650	COG0166	Belongs to the GPI family
Avin_17660	COG0738	Major facilitator superfamily
Avin_17740	COG2814	Major facilitator Superfamily
Avin_17760	COG0583	DNA-binding transcription factor activity
Avin_17770	COG3642	lipopolysaccharide core region biosynthetic process
Avin_17790	COG3850	Histidine kinase
Avin_17790	COG5002	protein histidine kinase activity
Avin_17820	COG4067	protein conserved in archaea
Avin_17820	COG0189	ligase activity
Avin_17850	COG0574	Belongs to the PEP-utilizing enzyme family
Avin_17850	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Avin_17870	COG3002	Belongs to the UPF0753 family
Avin_17950	COG1278	Cold shock
Avin_17990	COG1403	HNH endonuclease
Avin_18000	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Avin_18010	COG4191	Histidine kinase
Avin_18040	COG0477	Major facilitator Superfamily
Avin_18090	COG3416	Protein conserved in bacteria
Avin_18100	COG2824	Alkylphosphonate utilization operon protein PhnA
Avin_18190	COG0217	transcriptional regulatory protein
Avin_18240	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
Avin_18250	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Avin_18310	COG0826	peptidase U32
Avin_18430	COG1902	pentaerythritol trinitrate reductase activity
Avin_18450	COG1309	transcriptional regulator
Avin_18460	COG0604	alcohol dehydrogenase
Avin_18630	COG0745	RESPONSE REGULATOR receiver
Avin_18640	COG0642	Histidine kinase
Avin_18660	COG2900	Belongs to the SlyX family
Avin_18670	COG0747	negative chemotaxis
Avin_18680	COG0601	transmembrane transport
Avin_18710	COG3139	Protein of unknown function (DUF1315)
Avin_18730	COG0308	aminopeptidase N
Avin_18740	COG0427	acetyl-CoA hydrolase
Avin_18750	COG3344	reverse transcriptase
Avin_18790	COG2304	oxidoreductase activity
Avin_18830	COG0714	Associated with various cellular activities
Avin_18850	COG0392	lysyltransferase activity
Avin_18850	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
Avin_18900	COG0167	dihydroorotate dehydrogenase activity
Avin_18910	COG3130	regulation of translation
Avin_18930	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Avin_18930	COG0116	Belongs to the methyltransferase superfamily
Avin_18940	COG2027	D-alanyl-D-alanine carboxypeptidase
Avin_19010	COG1525	nuclease
Avin_19110	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Avin_19120	COG0513	Belongs to the DEAD box helicase family
Avin_19130	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
Avin_19140	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Avin_19150	COG5265	(ABC) transporter
Avin_19160	COG0583	DNA-binding transcription factor activity
Avin_19210	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Avin_19230	COG4659	FMN binding
Avin_19240	COG4658	electron transport chain
Avin_19260	COG2878	Part of a membrane complex involved in electron transport
Avin_19270	COG4657	Part of a membrane complex involved in electron transport
Avin_19280	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Avin_19280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Avin_19290	COG0489	protein tyrosine kinase activity
Avin_19300	COG0717	Belongs to the dCTP deaminase family
Avin_19400	COG3012	SEC-C Motif Domain Protein
Avin_19450	COG1199	ATP-dependent helicase activity
Avin_19500	COG0259	pyridoxamine-phosphate oxidase activity
Avin_19520	COG3133	Outer membrane lipoprotein
Avin_19530	COG2111	Na H antiporter
Avin_19530	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Avin_19540	COG1006	Multisubunit Na H antiporter MnhC subunit
Avin_19550	COG0651	ATP synthesis coupled electron transport
Avin_19560	COG1863	multisubunit Na H antiporter MnhE subunit
Avin_19570	COG2212	antiporter activity
Avin_19580	COG1320	monovalent cation:proton antiporter activity
Avin_19670	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Avin_19680	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Avin_19710	COG0356	it plays a direct role in the translocation of protons across the membrane
Avin_19730	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Avin_19730	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Avin_19740	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Avin_19760	COG3639	organic phosphonate transmembrane transporter activity
Avin_19770	COG3639	organic phosphonate transmembrane transporter activity
Avin_19790	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
Avin_19810	COG3622	Belongs to the hyi family
Avin_19830	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Avin_19840	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Avin_19850	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Avin_19880	COG1294	oxidase, subunit
Avin_19910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Avin_19970	COG0348	domain, Protein
Avin_19980	COG2010	Cytochrome c
Avin_20010	COG3278	Belongs to the heme-copper respiratory oxidase family
Avin_20050	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
Avin_20110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Avin_20120	COG0668	transmembrane transport
Avin_20130	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
Avin_20160	COG0564	pseudouridine synthase activity
Avin_20170	COG0071	Belongs to the small heat shock protein (HSP20) family
Avin_20200	COG1414	Transcriptional regulator
Avin_20210	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Avin_20220	COG1053	succinate dehydrogenase
Avin_20290	COG1063	alcohol dehydrogenase
Avin_20380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Avin_20420	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Avin_20440	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Avin_20450	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Avin_20460	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Avin_20470	COG0072	phenylalanine-tRNA ligase activity
Avin_20480	COG0776	regulation of translation
Avin_20540	COG2801	Transposase and inactivated derivatives
Avin_20550	COG2963	transposase activity
Avin_20570	COG2853	Lipoprotein
Avin_20590	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Avin_20600	COG0142	geranyltranstransferase activity
Avin_20610	COG1722	exodeoxyribonuclease VII activity
Avin_20630	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Avin_20640	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
Avin_20730	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Avin_20760	COG1657	PFAM Prenyltransferase squalene oxidase
Avin_20810	COG0583	DNA-binding transcription factor activity
Avin_20830	COG1902	pentaerythritol trinitrate reductase activity
Avin_20840	COG2814	Major facilitator Superfamily
Avin_20860	COG4396	Host-nuclease inhibitor protein Gam
Avin_20910	COG0145	ligase activity
Avin_20920	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
Avin_20930	COG4647	ligase activity
Avin_20940	COG3284	Transcriptional regulator
Avin_20980	COG1045	serine acetyltransferase
Avin_20990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Avin_21000	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Avin_21030	COG3415	Transposase
Avin_21030	COG2801	Transposase and inactivated derivatives
Avin_21060	COG1024	Enoyl-CoA hydratase
Avin_21100	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
Avin_21110	COG4266	Belongs to the allantoicase family
Avin_21180	COG1028	Short-chain dehydrogenase reductase Sdr
Avin_21190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Avin_21200	COG3433	isochorismatase activity
Avin_21200	COG1535	isochorismatase
Avin_21210	COG1021	2,3-dihydroxybenzoate-AMP ligase
Avin_21220	COG1169	isochorismate synthase
Avin_21250	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Avin_21300	COG3842	ATPase activity
Avin_21320	COG1053	succinate dehydrogenase
Avin_21400	COG0583	DNA-binding transcription factor activity
Avin_21420	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
Avin_21430	COG0277	FAD linked oxidase domain protein
Avin_21450	COG0765	amino acid transport
Avin_21460	COG0765	amino acid transport
Avin_21490	COG0625	glutathione transferase activity
Avin_21540	COG3712	iron ion homeostasis
Avin_21550	COG1595	DNA-templated transcription, initiation
Avin_21580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Avin_21590	COG0235	Class ii aldolase
Avin_21600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Avin_21610	COG1116	anion transmembrane transporter activity
Avin_21630	COG4206	TonB-dependent receptor
Avin_21660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Avin_21680	COG0583	DNA-binding transcription factor activity
Avin_21720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Avin_21730	COG0667	Aldo Keto reductase
Avin_21780	COG1609	Transcriptional regulator
Avin_21850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Avin_21870	COG2175	clavaminate synthase activity
Avin_21890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Avin_21900	COG1902	pentaerythritol trinitrate reductase activity
Avin_21930	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Avin_21950	COG0596	Alpha beta hydrolase
Avin_21960	COG2175	clavaminate synthase activity
Avin_22000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Avin_22030	COG1063	alcohol dehydrogenase
Avin_22060	COG2376	Dihydroxyacetone kinase
Avin_22070	COG1028	Short-chain dehydrogenase reductase Sdr
Avin_22080	COG1879	ABC-type sugar transport system periplasmic component
Avin_22090	COG1172	Belongs to the binding-protein-dependent transport system permease family
Avin_22100	COG1129	ABC transporter
Avin_22120	COG0698	ribose 5-phosphate isomerase
Avin_22130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Avin_22150	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Avin_22210	COG0148	phosphopyruvate hydratase activity
Avin_22220	COG4566	intracellular signal transduction
Avin_22250	COG0318	PFAM AMP-dependent synthetase and ligase
Avin_22260	COG0402	S-adenosylhomocysteine deaminase activity
Avin_22280	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Avin_22300	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Avin_22320	COG3415	Transposase
Avin_22320	COG2801	Transposase and inactivated derivatives
Avin_22370	COG0667	Aldo Keto reductase
Avin_22380	COG0625	glutathione transferase activity
Avin_22480	COG3265	gluconokinase activity
Avin_22520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Avin_22530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Avin_22550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Avin_22550	COG1116	anion transmembrane transporter activity
Avin_22600	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Avin_22620	COG0625	glutathione transferase activity
Avin_22630	COG4774	siderophore transport
Avin_22640	COG3712	iron ion homeostasis
Avin_22650	COG1595	DNA-templated transcription, initiation
Avin_22710	COG2217	Heavy metal translocating P-type atpase
Avin_22760	COG0783	Belongs to the Dps family
Avin_22840	COG3204	pilus organization
Avin_22880	COG3267	Type II secretory pathway component ExeA
Avin_22880	COG3409	Peptidoglycan-binding domain 1 protein
Avin_22970	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Avin_23000	COG0084	hydrolase, TatD family'
Avin_23020	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Avin_23050	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
Avin_23060	COG4181	ATPase activity
Avin_23130	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Avin_23170	COG0189	ligase activity
Avin_23200	COG1802	Transcriptional regulator
Avin_23260	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Avin_23290	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Avin_23310	COG0668	transmembrane transport
Avin_23350	COG0243	molybdopterin cofactor binding
Avin_23360	COG2146	nitrite reductase [NAD(P)H] activity
Avin_23370	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Avin_23380	COG2815	serine threonine protein kinase
Avin_23380	COG0515	serine threonine protein kinase
Avin_23390	COG2223	nitrite transmembrane transporter activity
Avin_23430	COG0436	Aminotransferase
Avin_23460	COG1116	anion transmembrane transporter activity
Avin_23460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Avin_23500	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Avin_23520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Avin_23530	COG0215	cysteine-tRNA ligase activity
Avin_23540	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Avin_23550	COG0544	peptidyl-prolyl cis-trans isomerase activity
Avin_23580	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Avin_23590	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Avin_23630	COG3243	poly(R)-hydroxyalkanoic acid synthase
Avin_23650	COG1028	Short-chain dehydrogenase reductase Sdr
Avin_23680	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
Avin_23690	COG0302	gtp cyclohydrolase
Avin_23720	COG1335	isochorismatase
Avin_23780	COG0235	Class ii aldolase
Avin_23800	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
Avin_23820	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Avin_23860	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Avin_23950	COG3293	Transposase
Avin_24000	COG1815	bacterial-type flagellum-dependent cell motility
Avin_24010	COG1558	bacterial-type flagellum-dependent cell motility
Avin_24020	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Avin_24030	COG1749	Flagellar hook protein flgE
Avin_24040	COG4787	bacterial-type flagellum-dependent cell motility
Avin_24050	COG4786	Flagellar basal body rod
Avin_24060	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
Avin_24070	COG1706	bacterial-type flagellum-dependent cell motility
Avin_24080	COG3951	Flagellar rod assembly protein muramidase FlgJ
Avin_24080	COG1705	Flagellar rod assembly protein muramidase FlgJ
Avin_24090	COG1256	bacterial-type flagellum assembly
Avin_24120	COG1987	bacterial-type flagellum assembly
Avin_24160	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Avin_24220	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Avin_24230	COG1766	The M ring may be actively involved in energy transduction
Avin_24290	COG2257	FlhB HrpN YscU SpaS Family
Avin_24330	COG1360	Flagellar Motor Protein
Avin_24340	COG0643	Histidine kinase
Avin_24340	COG2198	Histidine kinase
Avin_24350	COG0835	chemotaxis
Avin_24360	COG0840	transmembrane signaling receptor activity
Avin_24370	COG0840	transmembrane signaling receptor activity
Avin_24380	COG0840	transmembrane signaling receptor activity
Avin_24440	COG0747	negative chemotaxis
Avin_24520	COG2205	protein histidine kinase activity
Avin_24530	COG0745	RESPONSE REGULATOR receiver
Avin_24540	COG3158	transport of potassium into the cell
Avin_24590	COG3039	Transposase
Avin_24600	COG3344	reverse transcriptase
Avin_24610	COG3039	Transposase
Avin_24694	COG0529	Catalyzes the synthesis of activated sulfate
Avin_24700	COG2814	Major facilitator Superfamily
Avin_24740	COG3344	reverse transcriptase
Avin_24760	COG0583	DNA-binding transcription factor activity
Avin_24770	COG0604	alcohol dehydrogenase
Avin_24810	COG0392	lysyltransferase activity
Avin_24820	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Avin_24830	COG3568	Endonuclease Exonuclease Phosphatase
Avin_24900	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Avin_24910	COG0297	glycogen (starch) synthase activity
Avin_24920	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Avin_24930	COG1960	acyl-CoA dehydrogenase activity
Avin_24940	COG0477	Major facilitator Superfamily
Avin_24960	COG0583	DNA-binding transcription factor activity
Avin_24970	COG0659	secondary active sulfate transmembrane transporter activity
Avin_25040	COG0322	excinuclease ABC activity
Avin_25080	COG1309	transcriptional regulator
Avin_25170	COG2205	protein histidine kinase activity
Avin_25170	COG0784	Response regulator, receiver
Avin_25170	COG2198	Histidine kinase
Avin_25190	COG2200	EAL domain
Avin_25190	COG2199	diguanylate cyclase activity
Avin_25190	COG2202	Pas domain
Avin_25210	COG1960	acyl-CoA dehydrogenase activity
Avin_25220	COG1250	3-hydroxyacyl-CoA dehydrogenase
Avin_25230	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Avin_25250	COG0318	PFAM AMP-dependent synthetase and ligase
Avin_25270	COG4191	Histidine kinase
Avin_25360	COG4566	intracellular signal transduction
Avin_25370	COG1309	transcriptional regulator
Avin_25380	COG1752	Esterase of the alpha-beta hydrolase superfamily
Avin_25470	COG2963	transposase activity
Avin_25670	COG0069	glutamate synthase activity
Avin_25760	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Avin_25760	COG0543	2 iron, 2 sulfur cluster binding
Avin_25770	COG0071	Belongs to the small heat shock protein (HSP20) family
Avin_25780	COG0459	protein refolding
Avin_25790	COG0589	response to stress
Avin_25830	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Avin_25840	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Avin_25840	COG2010	Cytochrome c
Avin_25860	COG0667	Aldo Keto reductase
Avin_25870	COG0583	DNA-binding transcription factor activity
Avin_25880	COG1368	sulfuric ester hydrolase activity
Avin_25890	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Avin_25910	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Avin_25920	COG0640	Transcriptional regulator
Avin_25970	COG2271	Major facilitator Superfamily
Avin_25990	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Avin_26000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Avin_26020	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Avin_26020	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Avin_26040	COG1760	l-serine dehydratase
Avin_26050	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Avin_26090	COG0410	ABC transporter
Avin_26120	COG0559	Belongs to the binding-protein-dependent transport system permease family
Avin_26180	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
Avin_26190	COG1609	Transcriptional regulator
Avin_26200	COG1028	Short-chain dehydrogenase reductase Sdr
Avin_26270	COG5642	Protein of unknown function (DUF2384)
Avin_26290	COG2986	histidine ammonia-lyase
Avin_26300	COG0402	S-adenosylhomocysteine deaminase activity
Avin_26390	COG0583	DNA-binding transcription factor activity
Avin_26450	COG1120	ATPase activity
Avin_26480	COG2267	carboxylic ester hydrolase activity
Avin_26510	COG1279	arginine transmembrane transporter activity
Avin_26600	COG3501	Rhs element vgr protein
Avin_26690	COG0515	serine threonine protein kinase
Avin_26820	COG0477	Major facilitator Superfamily
Avin_26830	COG0579	oxidoreductase
Avin_26860	COG2186	Transcriptional regulator
Avin_26870	COG1609	Transcriptional regulator
Avin_26890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Avin_26940	COG4580	involved in the transport of maltose and maltodextrins
Avin_27030	COG0483	inositol monophosphate 1-phosphatase activity
Avin_27040	COG0612	Peptidase, M16
Avin_27090	COG1611	Belongs to the LOG family
Avin_27130	COG2814	Major facilitator Superfamily
Avin_27190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Avin_27200	COG4580	involved in the transport of maltose and maltodextrins
Avin_27220	COG0148	phosphopyruvate hydratase activity
Avin_27250	COG0800	Aldolase
Avin_27270	COG1737	Transcriptional regulator
Avin_27300	COG1609	Transcriptional regulator
Avin_27310	COG3265	gluconokinase activity
Avin_27320	COG1070	Carbohydrate kinase
Avin_27330	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Avin_27350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Avin_27380	COG0395	ABC-type sugar transport system, permease component
Avin_27390	COG1175	transmembrane transport
Avin_27420	COG1917	Cupin 2, conserved barrel domain protein
Avin_27420	COG4977	sequence-specific DNA binding
Avin_27440	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Avin_27450	COG2706	6-phosphogluconolactonase activity
Avin_27490	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Avin_27540	COG3344	reverse transcriptase
Avin_27550	COG0616	signal peptide processing
Avin_27590	COG2816	NAD+ diphosphatase activity
Avin_27710	COG1215	transferase activity, transferring glycosyl groups
Avin_27780	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Avin_27850	COG1334	flagellar protein FlaG
Avin_27860	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Avin_27870	COG1191	sigma factor activity
Avin_27910	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Avin_27920	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Avin_27940	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
Avin_27950	COG0745	RESPONSE REGULATOR receiver
Avin_27960	COG0840	transmembrane signaling receptor activity
Avin_27970	COG0840	transmembrane signaling receptor activity
Avin_27980	COG2201	protein-glutamate methylesterase activity
Avin_27990	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Avin_28000	COG0366	Alpha amylase catalytic
Avin_28020	COG1944	ATP diphosphatase activity
Avin_28030	COG2081	HI0933 family
Avin_28070	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Avin_28160	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Avin_28170	COG1648	precorrin-2 dehydrogenase activity
Avin_28170	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Avin_28180	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Avin_28190	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Avin_28200	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Avin_28210	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Avin_28230	COG0492	ferredoxin-NADP+ reductase activity
Avin_28240	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Avin_28250	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
Avin_28260	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Avin_28270	COG0542	response to heat
Avin_28280	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Avin_28290	COG1278	Cold shock
Avin_28360	COG0482	sulfurtransferase activity
Avin_28370	COG2915	High frequency lysogenization protein hflD homolog
Avin_28390	COG2850	peptidyl-arginine hydroxylation
Avin_28400	COG2153	protein acetylation
Avin_28440	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Avin_28450	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Avin_28460	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Avin_28460	COG0649	NAD binding
Avin_28500	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Avin_28510	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Avin_28530	COG0713	ATP synthesis coupled electron transport
Avin_28560	COG1007	ATP synthesis coupled electron transport
Avin_28580	COG0745	RESPONSE REGULATOR receiver
Avin_28590	COG3212	peptidase
Avin_28600	COG0720	synthase
Avin_28610	COG0741	lytic transglycosylase activity
Avin_28630	COG1459	type II secretion system
Avin_28660	COG2135	peptidase activity
Avin_28710	COG0488	(ABC) transporter
Avin_28720	COG1968	undecaprenyl-diphosphatase activity
Avin_28760	COG0316	Belongs to the HesB IscA family
Avin_28760	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Avin_28780	COG1538	Outer membrane efflux protein
Avin_28840	COG1115	amino acid carrier protein
Avin_28850	COG2911	Protein conserved in bacteria
Avin_28860	COG0729	surface antigen
Avin_28880	COG0708	Exodeoxyribonuclease III
Avin_28960	COG0300	oxidoreductase activity
Avin_28980	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Avin_29010	COG4191	Histidine kinase
Avin_29030	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Avin_29050	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Avin_29190	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Avin_29210	COG1469	GTP cyclohydrolase I activity
Avin_29280	COG1653	transport
Avin_29290	COG5002	protein histidine kinase activity
Avin_29290	COG0784	Response regulator, receiver
Avin_29290	COG2205	protein histidine kinase activity
Avin_29310	COG0322	excinuclease ABC activity
Avin_29320	COG4702	Belongs to the UPF0303 family
Avin_29350	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Avin_29400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Avin_29410	COG1116	anion transmembrane transporter activity
Avin_29450	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Avin_29500	COG0577	efflux transmembrane transporter activity
Avin_29580	COG1982	Orn Lys Arg decarboxylase major
Avin_29590	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Avin_29600	COG0328	RNA-DNA hybrid ribonuclease activity
Avin_29630	COG0741	lytic transglycosylase activity
Avin_29630	COG1388	LysM domain
Avin_29650	COG4166	transmembrane transport
Avin_29660	COG4174	ABC transporter (Permease)
Avin_29670	COG4239	(ABC) transporter, permease
Avin_29680	COG4172	Belongs to the ABC transporter superfamily
Avin_29700	COG2233	PERMEase
Avin_29740	COG0045	succinate-CoA ligase (ADP-forming) activity
Avin_29790	COG1053	succinate dehydrogenase
Avin_29800	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
Avin_29810	COG2009	succinate dehydrogenase
Avin_29860	COG3123	guanosine phosphorylase activity
Avin_29870	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Avin_29900	COG3206	protein involved in exopolysaccharide biosynthesis
Avin_29900	COG0489	protein tyrosine kinase activity
Avin_29910	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
Avin_29920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Avin_29930	COG1132	(ABC) transporter
Avin_29940	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Avin_29970	COG0463	Glycosyl transferase, family 2
Avin_29990	COG0438	transferase activity, transferring glycosyl groups
Avin_30000	COG0438	transferase activity, transferring glycosyl groups
Avin_30010	COG0438	transferase activity, transferring glycosyl groups
Avin_30040	COG0438	transferase activity, transferring glycosyl groups
Avin_30050	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Avin_30070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Avin_30100	COG1216	Glycosyl transferase, family 2
Avin_30120	COG1442	glycosyl transferase family 8
Avin_30120	COG1216	Glycosyl transferase, family 2
Avin_30140	COG0318	PFAM AMP-dependent synthetase and ligase
Avin_30160	COG2030	dehydratase
Avin_30170	COG0402	S-adenosylhomocysteine deaminase activity
Avin_30210	COG0673	inositol 2-dehydrogenase activity
Avin_30280	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Avin_30290	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Avin_30300	COG3115	cell septum assembly
Avin_30320	COG1196	nuclear chromosome segregation
Avin_30330	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Avin_30350	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Avin_30410	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
Avin_30460	COG0455	bacterial-type flagellum organization
Avin_30480	COG1116	anion transmembrane transporter activity
Avin_30490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Avin_30500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Avin_30510	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Avin_30520	COG0431	NADPH-dependent FMN reductase
Avin_30530	COG0450	alkyl hydroperoxide reductase
Avin_30540	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
Avin_30570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Avin_30580	COG4569	acetaldehyde dehydrogenase (acetylating) activity
Avin_30640	COG3550	peptidyl-serine autophosphorylation
Avin_30680	COG0798	PFAM Bile acid sodium symporter
Avin_30710	COG2871	sodium ion transport
Avin_30890	COG4221	oxidoreductase activity
Avin_30900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Avin_30910	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
Avin_30930	COG2175	clavaminate synthase activity
Avin_30960	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Avin_31000	COG1028	Short-chain dehydrogenase reductase Sdr
Avin_31100	COG1960	acyl-CoA dehydrogenase activity
Avin_31140	COG2205	protein histidine kinase activity
Avin_31150	COG0745	RESPONSE REGULATOR receiver
Avin_31190	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
Avin_31200	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
Avin_31210	COG1301	dicarboxylic acid transport
Avin_31220	COG0583	DNA-binding transcription factor activity
Avin_31250	COG3384	dioxygenase
Avin_31260	COG0583	DNA-binding transcription factor activity
Avin_31270	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Avin_31280	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Avin_31290	COG2828	Protein conserved in bacteria
Avin_31330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Avin_31370	COG0235	Class ii aldolase
Avin_31380	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Avin_31400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Avin_31420	COG0673	inositol 2-dehydrogenase activity
Avin_31440	COG1335	isochorismatase
Avin_31520	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Avin_31530	COG2011	ABC-type metal ion transport system permease component
Avin_31570	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
Avin_31580	COG1518	maintenance of DNA repeat elements
Avin_31680	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Avin_31720	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
Avin_31730	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
Avin_31740	COG4208	sulfate ABC transporter
Avin_31760	COG3781	membrane
Avin_31840	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Avin_31860	COG4118	positive regulation of growth
Avin_31910	COG4680	protein conserved in bacteria
Avin_31970	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
Avin_32100	COG3385	transposase activity
Avin_32170	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Avin_32180	COG1960	acyl-CoA dehydrogenase activity
Avin_32190	COG3039	Transposase
Avin_32210	COG1846	Transcriptional regulator
Avin_32250	COG2271	Major facilitator Superfamily
Avin_32340	COG1073	alpha beta
Avin_32370	COG2814	Major facilitator Superfamily
Avin_32390	COG1064	alcohol dehydrogenase
Avin_32440	COG1028	Short-chain dehydrogenase reductase Sdr
Avin_32460	COG2207	Transcriptional regulator
Avin_32500	COG0667	Aldo Keto reductase
Avin_32520	COG0300	oxidoreductase activity
Avin_32530	COG0667	Aldo Keto reductase
Avin_32550	COG0667	Aldo Keto reductase
Avin_32690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Avin_32700	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Avin_32720	COG0745	RESPONSE REGULATOR receiver
Avin_32730	COG2853	Lipoprotein
Avin_32800	COG0514	ATP-dependent DNA helicase (RecQ)
Avin_32820	COG2832	Protein of unknown function (DUF454)
Avin_32850	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Avin_32860	COG0542	response to heat
Avin_32880	COG0121	glutamine amidotransferase
Avin_32910	COG1295	ribonuclease BN
Avin_32930	COG2983	Belongs to the UPF0260 family
Avin_32960	COG3100	YcgL domain-containing protein
Avin_33030	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Avin_33040	COG0406	alpha-ribazole phosphatase activity
Avin_33050	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Avin_33080	COG1492	cobalamin metabolic process
Avin_33100	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Avin_33110	COG0778	Nitroreductase
Avin_33120	COG1797	cobyrinic acid a,c-diamide synthase activity
Avin_33150	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Avin_33160	COG0505	Belongs to the CarA family
Avin_33170	COG0791	NLP P60 protein
Avin_33180	COG0791	NLP P60 protein
Avin_33210	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Avin_33230	COG0037	tRNA processing
Avin_33250	COG3091	SprT-like family
Avin_33290	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Avin_33290	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Avin_33300	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Avin_33320	COG3293	Transposase
Avin_33360	COG1943	Transposase
Avin_33370	COG2226	methyltransferase
Avin_33470	COG0861	Integral membrane protein TerC family
Avin_33550	COG2801	Transposase and inactivated derivatives
Avin_33550	COG3415	Transposase
Avin_33610	COG4580	involved in the transport of maltose and maltodextrins
Avin_33670	COG1609	Transcriptional regulator
Avin_33690	COG2814	Major facilitator Superfamily
Avin_33690	COG0477	Major facilitator Superfamily
Avin_33700	COG1082	Xylose isomerase domain protein TIM barrel
Avin_33740	COG2963	transposase activity
Avin_33750	COG0583	DNA-binding transcription factor activity
Avin_33780	COG2031	fatty acid transporter
Avin_33790	COG1250	3-hydroxyacyl-CoA dehydrogenase
Avin_33820	COG1785	Belongs to the alkaline phosphatase family
Avin_33840	COG0604	alcohol dehydrogenase
Avin_33890	COG2084	Dehydrogenase
Avin_33920	COG1609	Transcriptional regulator
Avin_34050	COG0705	Rhomboid family
Avin_34060	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Avin_34070	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Avin_34160	COG1286	toxin biosynthetic process
Avin_34180	COG0285	dihydrofolate synthase activity
Avin_34190	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Avin_34210	COG0135	phosphoribosylanthranilate isomerase activity
Avin_34260	COG0473	3-isopropylmalate dehydrogenase activity
Avin_34280	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Avin_34320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Avin_34340	COG0800	Aldolase
Avin_34360	COG0745	RESPONSE REGULATOR receiver
Avin_34420	COG2239	Acts as a magnesium transporter
Avin_34440	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Avin_34460	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Avin_34500	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Avin_34530	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Avin_34560	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Avin_34570	COG2301	Belongs to the HpcH HpaI aldolase family
Avin_34660	COG2154	pterin-4-alpha-carbinolamine dehydratase
Avin_34860	COG0271	Belongs to the BolA IbaG family
Avin_34880	COG0114	fumarate hydratase activity
Avin_34940	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Avin_34940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Avin_34950	COG1846	Transcriptional regulator
Avin_34960	COG0367	asparagine synthase
Avin_34980	COG1363	Peptidase, m42
Avin_35000	COG3089	Belongs to the UPF0270 family
Avin_35020	COG1253	flavin adenine dinucleotide binding
Avin_35030	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Avin_35040	COG3162	membrane
Avin_35090	COG2853	Lipoprotein
Avin_35100	COG1560	Kdo2-lipid A biosynthetic process
Avin_35110	COG0850	regulation of cytokinetic process
Avin_35120	COG2894	cell division
Avin_35130	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Avin_35140	COG0564	pseudouridine synthase activity
Avin_35150	COG1362	aminopeptidase activity
Avin_35200	COG3339	Conserved Protein
Avin_35210	COG0545	Peptidyl-prolyl cis-trans isomerase
Avin_35230	COG2205	protein histidine kinase activity
Avin_35240	COG3174	membrane
Avin_35320	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Avin_35330	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
Avin_35340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Avin_35360	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Avin_35370	COG0425	Belongs to the sulfur carrier protein TusA family
Avin_35380	COG4783	chaperone-mediated protein folding
Avin_35390	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Avin_35420	COG0471	metal ion transport
Avin_35470	COG1064	alcohol dehydrogenase
Avin_35480	COG1028	Short-chain dehydrogenase reductase Sdr
Avin_35520	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Avin_35660	COG3846	protein secretion by the type IV secretion system
Avin_35690	COG3451	type IV secretory pathway VirB4
Avin_35710	COG3838	Conjugal transfer protein Trbc
Avin_35720	COG4962	Type ii secretion system protein e
Avin_35760	COG0583	DNA-binding transcription factor activity
Avin_35810	COG1309	transcriptional regulator
Avin_35820	COG2249	NAD(P)H dehydrogenase (quinone) activity
Avin_35850	COG0583	DNA-binding transcription factor activity
Avin_35860	COG2814	Major facilitator Superfamily
Avin_35890	COG0583	DNA-binding transcription factor activity
Avin_35900	COG2814	Major facilitator Superfamily
Avin_35940	COG4959	Type IV secretory pathway protease TraF
Avin_36040	COG2003	Belongs to the UPF0758 family
Avin_36050	COG0270	DNA (cytosine-5-)-methyltransferase activity
Avin_36110	COG3657	addiction module killer protein
Avin_36150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Avin_36164	COG3293	Transposase
Avin_36330	COG2963	transposase activity
Avin_36460	COG2801	Transposase and inactivated derivatives
Avin_36490	COG2801	Transposase and inactivated derivatives
Avin_36590	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Avin_36600	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Avin_36610	COG0602	queuosine metabolic process
Avin_36620	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
Avin_36680	COG0824	Thioesterase
Avin_36690	COG2255	four-way junction helicase activity
Avin_36710	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Avin_36730	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Avin_36750	COG0442	prolyl-tRNA aminoacylation
Avin_36810	COG1295	ribonuclease BN
Avin_36850	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Avin_36860	COG0628	permease
Avin_36890	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Avin_36900	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Avin_36920	COG3077	Addiction module antitoxin, RelB DinJ family
Avin_36940	COG3122	Protein conserved in bacteria
Avin_36950	COG3956	TIGRFAM MazG family protein
Avin_36990	COG2819	hydrolase of the alpha beta superfamily
Avin_37000	COG0500	methyltransferase
Avin_37060	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Avin_37070	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Avin_37090	COG0784	Response regulator, receiver
Avin_37090	COG2205	protein histidine kinase activity
Avin_37090	COG5002	protein histidine kinase activity
Avin_37100	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Avin_37230	COG3561	AntA/AntB antirepressor
Avin_37620	COG4695	Portal protein
Avin_37650	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Avin_37690	COG2308	Evidence 4 Homologs of previously reported genes of
Avin_37700	COG0693	protein deglycase activity
Avin_37710	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Avin_37780	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
Avin_37800	COG1902	pentaerythritol trinitrate reductase activity
Avin_37830	COG3300	MHYT domain
Avin_37830	COG5001	Diguanylate cyclase
Avin_37880	COG2831	hemolysin activation secretion protein
Avin_37930	COG0583	DNA-binding transcription factor activity
Avin_37950	COG0604	alcohol dehydrogenase
Avin_37950	COG3321	synthase
Avin_37950	COG1028	Short-chain dehydrogenase reductase Sdr
Avin_38000	COG2814	Major facilitator Superfamily
Avin_38040	COG0667	Aldo Keto reductase
Avin_38050	COG0667	Aldo Keto reductase
Avin_38070	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Avin_38080	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Avin_38090	COG1309	transcriptional regulator
Avin_38150	COG0656	L-ascorbic acid biosynthetic process
Avin_38170	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Avin_38180	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Avin_38210	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Avin_38220	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
Avin_38230	COG1414	Transcriptional regulator
Avin_38240	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Avin_38250	COG3485	protocatechuate 3,4-dioxygenase
Avin_38260	COG3485	protocatechuate 3,4-dioxygenase
Avin_38270	COG0583	DNA-binding transcription factor activity
Avin_38280	COG0788	formyltetrahydrofolate deformylase activity
Avin_38320	COG2925	Exonuclease
Avin_38370	COG0714	Associated with various cellular activities
Avin_38400	COG0589	response to stress
Avin_38420	COG3706	GGDEF domain
Avin_38440	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
Avin_38440	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
Avin_38480	COG0583	DNA-binding transcription factor activity
Avin_38520	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
Avin_38530	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Avin_38550	COG2137	regulation of response to DNA damage stimulus
Avin_38560	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Avin_38570	COG1546	Belongs to the CinA family
Avin_38640	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Avin_38660	COG0840	transmembrane signaling receptor activity
Avin_38670	COG0840	transmembrane signaling receptor activity
Avin_38700	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Avin_38710	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Avin_38720	COG0585	pseudouridine synthase activity
Avin_38730	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Avin_38740	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
Avin_38750	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
Avin_38770	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Avin_38800	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Avin_38810	COG0504	CTP synthase activity
Avin_38830	COG0825	malonyl-CoA metabolic process
Avin_38850	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Avin_38860	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Avin_38870	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Avin_38880	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Avin_38930	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Avin_38950	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Avin_38960	COG0233	cytoplasmic translational termination
Avin_38970	COG0528	UMP kinase activity
Avin_38980	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Avin_38990	COG0052	Belongs to the universal ribosomal protein uS2 family
Avin_39000	COG0024	Methionine aminopeptidase
Avin_39010	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Avin_39020	COG0436	Aminotransferase
Avin_39030	COG0025	NhaP-type Na H and K H
Avin_39080	COG1393	Belongs to the ArsC family
Avin_39090	COG2171	N-acyltransferase activity
Avin_39130	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Avin_39160	COG2226	methyltransferase
Avin_39220	COG1131	(ABC) transporter
Avin_39240	COG0742	ribosomal rna small subunit methyltransferase
Avin_39260	COG1801	Protein of unknown function DUF72
Avin_39270	COG1214	PFAM Peptidase M22, glycoprotease
Avin_39280	COG0563	adenylate kinase activity
Avin_39300	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Avin_39340	COG1073	alpha beta
Avin_39390	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Avin_39400	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Avin_39430	COG1902	pentaerythritol trinitrate reductase activity
Avin_39450	COG4681	YaeQ
Avin_39520	COG1607	acyl-coa hydrolase
Avin_39530	COG0335	large ribosomal subunit rRNA binding
Avin_39540	COG0336	Belongs to the RNA methyltransferase TrmD family
Avin_39550	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Avin_39560	COG0228	four-way junction DNA binding
Avin_39570	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Avin_39600	COG4536	flavin adenine dinucleotide binding
Avin_39610	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
Avin_39620	COG0494	nUDIX hydrolase
Avin_39640	COG1376	ErfK ybiS ycfS ynhG family protein
Avin_39640	COG1388	LysM domain
Avin_39670	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Avin_39680	COG0590	tRNA wobble adenosine to inosine editing
Avin_39690	COG2132	Multicopper oxidase
Avin_39750	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Avin_39770	COG1570	exodeoxyribonuclease VII activity
Avin_39790	COG0739	heme binding
Avin_39900	COG0583	DNA-binding transcription factor activity
Avin_39910	COG0402	S-adenosylhomocysteine deaminase activity
Avin_39950	COG0477	Major facilitator Superfamily
Avin_39970	COG2909	trisaccharide binding
Avin_39990	COG0371	Dehydrogenase
Avin_40020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Avin_40050	COG4993	Dehydrogenase
Avin_40070	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Avin_40120	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Avin_40130	COG2356	endonuclease I
Avin_40140	COG3647	Membrane
Avin_40170	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Avin_40190	COG0436	Aminotransferase
Avin_40240	COG1160	GTP binding
Avin_40270	COG2976	Protein conserved in bacteria
Avin_40280	COG0124	histidyl-tRNA synthetase
Avin_40290	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Avin_40330	COG0105	UTP biosynthetic process
Avin_40360	COG0443	Heat shock 70 kDa protein
Avin_40370	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
Avin_40380	COG0316	Belongs to the HesB IscA family
Avin_40400	COG1104	cysteine desulfurase activity
Avin_40470	COG1862	Preprotein translocase
Avin_40480	COG0343	queuine tRNA-ribosyltransferase activity
Avin_40490	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Avin_40500	COG0582	viral genome integration into host DNA
Avin_40520	COG2801	Transposase and inactivated derivatives
Avin_40540	COG2963	transposase activity
Avin_40590	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Avin_40600	COG3657	addiction module killer protein
Avin_40720	COG0268	Binds directly to 16S ribosomal RNA
Avin_40730	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Avin_40750	COG3045	CreA protein
Avin_40760	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Avin_40770	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Avin_40780	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Avin_40790	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Avin_40810	COG0142	geranyltranstransferase activity
Avin_40820	COG0545	Peptidyl-prolyl cis-trans isomerase
Avin_40830	COG2862	Uncharacterized protein family, UPF0114
Avin_40850	COG1067	ATP-dependent peptidase activity
Avin_40940	COG1595	DNA-templated transcription, initiation
Avin_40960	COG0488	(ABC) transporter
Avin_40970	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Avin_40980	COG0523	cobalamin synthesis protein
Avin_41000	COG2879	small protein
Avin_41010	COG1966	Carbon starvation protein
Avin_41060	COG2020	methyltransferase activity
Avin_41090	COG1970	mechanosensitive ion channel activity
Avin_41100	COG0386	Belongs to the glutathione peroxidase family
Avin_41120	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Avin_41140	COG2885	chlorophyll binding
Avin_41140	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Avin_41150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Avin_41180	COG1525	nuclease
Avin_41210	COG2989	Protein conserved in bacteria
Avin_41230	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Avin_41240	COG2813	Specifically methylates the guanine in position
Avin_41250	COG2119	membrane
Avin_41260	COG2119	membrane
Avin_41270	COG0501	Belongs to the peptidase M48B family
Avin_41280	COG2135	peptidase activity
Avin_41360	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Avin_41370	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Avin_41380	COG1090	epimerase
Avin_41390	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
Avin_41410	COG0789	Transcriptional regulator
Avin_41430	COG0415	Belongs to the DNA photolyase family
Avin_41440	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Avin_41450	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Avin_41470	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Avin_41480	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Avin_41510	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Avin_41520	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Avin_41530	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Avin_41540	COG0193	aminoacyl-tRNA hydrolase activity
Avin_41610	COG1025	Belongs to the peptidase M16 family
Avin_41640	COG0535	radical SAM domain protein
Avin_41660	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
Avin_41670	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Avin_41690	COG3284	Transcriptional regulator
Avin_41710	COG1028	Short-chain dehydrogenase reductase Sdr
Avin_41720	COG3199	ATP-NAD kinase
Avin_41730	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Avin_41740	COG0022	dehydrogenase e1 component
Avin_41760	COG1063	alcohol dehydrogenase
Avin_41820	COG1509	lysine 2,3-aminomutase activity
Avin_41840	COG0583	DNA-binding transcription factor activity
Avin_41860	COG2801	Transposase and inactivated derivatives
Avin_41880	COG2963	transposase activity
Avin_41890	COG2814	Major facilitator Superfamily
Avin_41950	COG0659	secondary active sulfate transmembrane transporter activity
Avin_41970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Avin_42030	COG3093	addiction module antidote protein HigA
Avin_42060	COG0583	DNA-binding transcription factor activity
Avin_42070	COG3135	benzoate transporter
Avin_42100	COG0543	2 iron, 2 sulfur cluster binding
Avin_42100	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Avin_42110	COG2814	Major facilitator Superfamily
Avin_42120	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Avin_42130	COG4569	acetaldehyde dehydrogenase (acetylating) activity
Avin_42150	COG3971	2-oxopent-4-enoate hydratase activity
Avin_42210	COG3384	dioxygenase
Avin_42330	COG1574	metal-dependent hydrolase with the TIM-barrel fold
Avin_42350	COG1335	isochorismatase
Avin_42370	COG0675	Transposase, IS605 OrfB family
Avin_42390	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
Avin_42440	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Avin_42450	COG3008	intermembrane lipid transfer
Avin_42460	COG2995	paraquat-inducible protein a
Avin_42470	COG2995	paraquat-inducible protein a
Avin_42490	COG1183	phosphatidylcholine synthase activity
Avin_42500	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Avin_42520	COG0028	Belongs to the TPP enzyme family
Avin_42540	COG3098	single-species biofilm formation
Avin_42560	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Avin_42600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Avin_42620	COG1489	DNA binding
Avin_42640	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Avin_42650	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Avin_42670	COG3852	Histidine kinase
Avin_42690	COG0617	tRNA 3'-terminal CCA addition
Avin_42720	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Avin_42730	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Avin_42740	COG0166	Belongs to the GPI family
Avin_42780	COG1185	polyribonucleotide nucleotidyltransferase activity
Avin_42790	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Avin_42810	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Avin_42820	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Avin_42830	COG0195	Participates in both transcription termination and antitermination
Avin_42840	COG0779	Required for maturation of 30S ribosomal subunits
Avin_42850	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Avin_42860	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Avin_42870	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Avin_42890	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Avin_42900	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Avin_42950	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Avin_42960	COG0484	heat shock protein binding
Avin_42970	COG0443	Heat shock 70 kDa protein
Avin_42980	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Avin_42990	COG0497	DNA recombination
Avin_43020	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Avin_43030	COG2914	Belongs to the UPF0125 (RnfH) family
Avin_43050	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Avin_43060	COG2186	Transcriptional regulator
Avin_43070	COG1620	l-lactate permease
Avin_43080	COG0247	lactate metabolic process
Avin_43090	COG1139	Iron-sulfur cluster binding protein
Avin_43120	COG2205	protein histidine kinase activity
Avin_43200	COG0528	UMP kinase activity
Avin_43210	COG0528	UMP kinase activity
Avin_43230	COG3960	tartronate-semialdehyde synthase activity
Avin_43240	COG0583	DNA-binding transcription factor activity
Avin_43250	COG0281	malic enzyme
Avin_43260	COG1620	l-lactate permease
Avin_43290	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Avin_43300	COG3193	protein, possibly involved in utilization of glycolate and propanediol
Avin_43310	COG0247	lactate metabolic process
Avin_43320	COG0277	FAD linked oxidase domain protein
Avin_43330	COG0277	FAD linked oxidase domain protein
Avin_43340	COG2186	Transcriptional regulator
Avin_43350	COG0148	phosphopyruvate hydratase activity
Avin_43380	COG3835	regulator
Avin_43390	COG1929	Belongs to the glycerate kinase type-1 family
Avin_43400	COG3960	tartronate-semialdehyde synthase activity
Avin_43410	COG3622	Belongs to the hyi family
Avin_43420	COG2084	Dehydrogenase
Avin_43440	COG1741	Belongs to the pirin family
Avin_43490	COG3150	esterase
Avin_43500	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Avin_43520	COG1172	Belongs to the binding-protein-dependent transport system permease family
Avin_43600	COG1172	Belongs to the binding-protein-dependent transport system permease family
Avin_43610	COG1129	ABC transporter
Avin_43640	COG1960	acyl-CoA dehydrogenase activity
Avin_43660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Avin_43690	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Avin_43690	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Avin_43850	COG0626	cystathionine gamma-synthase activity
Avin_43870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Avin_43900	COG3829	transcription factor binding
Avin_44030	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Avin_44040	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Avin_44070	COG2995	paraquat-inducible protein a
Avin_44080	COG2995	paraquat-inducible protein a
Avin_44090	COG3008	intermembrane lipid transfer
Avin_44090	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Avin_44110	COG2963	transposase activity
Avin_44150	COG1595	DNA-templated transcription, initiation
Avin_44170	COG0628	permease
Avin_44230	COG1132	(ABC) transporter
Avin_44240	COG0156	8-amino-7-oxononanoate synthase activity
Avin_44250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Avin_44290	COG0456	acetyltransferase
Avin_44310	COG1213	nucleotidyl transferase
Avin_44350	COG1183	phosphatidylcholine synthase activity
Avin_44450	COG1216	Glycosyl transferase, family 2
Avin_44450	COG0463	Glycosyl transferase, family 2
Avin_44500	COG0583	DNA-binding transcription factor activity
Avin_44530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Avin_44580	COG0494	nUDIX hydrolase
Avin_44600	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Avin_44610	COG1519	Transferase
Avin_44630	COG0667	Aldo Keto reductase
Avin_44680	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Avin_44680	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Avin_44710	COG1132	(ABC) transporter
Avin_44740	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Avin_44760	COG1442	glycosyl transferase family 8
Avin_44790	COG0438	transferase activity, transferring glycosyl groups
Avin_44800	COG2192	nodulation
Avin_44840	COG0438	transferase activity, transferring glycosyl groups
Avin_44850	COG0859	PFAM glycosyl transferase family 9
Avin_44860	COG0859	PFAM glycosyl transferase family 9
Avin_44940	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Avin_44980	COG2026	Addiction module toxin, RelE StbE family
Avin_45040	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
Avin_45050	COG0583	DNA-binding transcription factor activity
Avin_45080	COG1942	4-Oxalocrotonate Tautomerase
Avin_45090	COG3263	regulation of cellular component size
Avin_45100	COG3264	Mechanosensitive ion channel
Avin_45100	COG1196	nuclear chromosome segregation
Avin_45110	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Avin_45130	COG0730	response to heat
Avin_45140	COG3118	belongs to the thioredoxin family
Avin_45160	COG1192	Involved in chromosome partitioning
Avin_45170	COG0583	DNA-binding transcription factor activity
Avin_45180	COG2814	Major facilitator Superfamily
Avin_45190	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Avin_45200	COG0493	'glutamate synthase
Avin_45210	COG0069	glutamate synthase activity
Avin_45210	COG0067	glutamate synthase
Avin_45210	COG0070	glutamate synthase
Avin_45240	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Avin_45250	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Avin_45300	COG0443	Heat shock 70 kDa protein
Avin_45330	COG0281	malic enzyme
Avin_45340	COG0254	rRNA binding
Avin_45350	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Avin_45360	COG0018	arginyl-trna synthetase
Avin_45390	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Avin_45410	COG2226	methyltransferase
Avin_45430	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Avin_45440	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Avin_45450	COG0140	phosphoribosyl-ATP diphosphatase activity
Avin_45460	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Avin_45470	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Avin_45550	COG1490	D-aminoacyl-tRNA deacylase activity
Avin_45590	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Avin_45640	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Avin_45650	COG0058	SHG alpha-glucan phosphorylase activity
Avin_45710	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Avin_45760	COG0148	phosphopyruvate hydratase activity
Avin_45770	COG0149	triose-phosphate isomerase activity
Avin_45820	COG3344	reverse transcriptase
Avin_45840	COG0301	tRNA thio-modification
Avin_45840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Avin_45890	COG3852	Histidine kinase
Avin_45910	COG0450	alkyl hydroperoxide reductase
Avin_45920	COG1960	acyl-CoA dehydrogenase activity
Avin_45940	COG0778	Nitroreductase
Avin_45950	COG0716	FMN binding
Avin_45990	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Avin_46000	COG0739	heme binding
Avin_46010	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Avin_46020	COG3344	reverse transcriptase
Avin_46030	COG0316	Belongs to the HesB IscA family
Avin_46040	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Avin_46060	COG0537	adenosine 5'-monophosphoramidase activity
Avin_46070	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
Avin_46080	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Avin_46090	COG1765	OsmC-like protein
Avin_46110	COG0134	indole-3-glycerol-phosphate synthase activity
Avin_46120	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Avin_46130	COG0512	Glutamine amidotransferase of anthranilate synthase
Avin_46140	COG0586	Pfam SNARE associated Golgi protein
Avin_46160	COG0508	dehydrogenase complex catalyzes the overall conversion of
Avin_46160	COG0022	dehydrogenase e1 component
Avin_46170	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Avin_46190	COG0789	Transcriptional regulator
Avin_46210	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Avin_46220	COG1335	isochorismatase
Avin_46260	COG2249	NAD(P)H dehydrogenase (quinone) activity
Avin_46280	COG2169	Transcriptional regulator
Avin_46280	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Avin_46320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Avin_46350	COG4935	Belongs to the peptidase S8 family
Avin_46350	COG1404	Belongs to the peptidase S8 family
Avin_46380	COG0477	Major facilitator Superfamily
Avin_46400	COG1538	Outer membrane efflux protein
Avin_46420	COG0384	phenazine biosynthesis protein PhzF
Avin_46440	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Avin_46470	COG0583	DNA-binding transcription factor activity
Avin_46550	COG0745	RESPONSE REGULATOR receiver
Avin_46660	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Avin_46670	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Avin_46680	COG0583	DNA-binding transcription factor activity
Avin_46700	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Avin_46710	COG0477	Major facilitator Superfamily
Avin_46750	COG1028	Short-chain dehydrogenase reductase Sdr
Avin_46770	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
Avin_46780	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Avin_46800	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
Avin_46840	COG2967	ApaG domain
Avin_46850	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Avin_46860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Avin_46870	COG2766	serine protein kinase
Avin_46880	COG2718	Belongs to the UPF0229 family
Avin_46890	COG2719	SpoVR family
Avin_46900	COG0617	tRNA 3'-terminal CCA addition
Avin_46930	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Avin_46950	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Avin_46960	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Avin_46970	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Avin_46980	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Avin_46990	COG0358	DNA primase activity
Avin_47000	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Avin_47010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Avin_47040	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
Avin_47070	COG1058	Belongs to the CinA family
Avin_47070	COG1546	Belongs to the CinA family
Avin_47080	COG3546	catalase activity
Avin_47160	COG1120	ATPase activity
Avin_47170	COG1595	DNA-templated transcription, initiation
Avin_47180	COG3712	iron ion homeostasis
Avin_47190	COG4772	TonB-dependent receptor
Avin_47210	COG2267	carboxylic ester hydrolase activity
Avin_47260	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Avin_47260	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Avin_47290	COG1178	ABC-type Fe3 transport system permease component
Avin_47310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Avin_47320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Avin_47330	COG0006	proline dipeptidase activity
Avin_47340	COG3079	Belongs to the UPF0149 family
Avin_47370	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Avin_47400	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Avin_47430	COG0248	Ppx GppA phosphatase
Avin_47440	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Avin_47460	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
Avin_47470	COG1671	Belongs to the UPF0178 family
Avin_47510	COG0861	Integral membrane protein TerC family
Avin_47520	COG0488	(ABC) transporter
Avin_47620	COG0165	Argininosuccinate lyase
Avin_47670	COG1965	Belongs to the frataxin family
Avin_47710	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Avin_47730	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Avin_47770	COG0432	Pfam Uncharacterised protein family UPF0047
Avin_47780	COG0004	ammonium transporteR
Avin_47790	COG0347	Belongs to the P(II) protein family
Avin_47800	COG2960	long-chain fatty acid transporting porin activity
Avin_47810	COG0606	chelatase, subunit chli
Avin_47830	COG0583	DNA-binding transcription factor activity
Avin_47850	COG1741	Belongs to the pirin family
Avin_47920	COG0753	catalase activity
Avin_47930	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Avin_47980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Avin_48010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Avin_48030	COG1012	belongs to the aldehyde dehydrogenase family
Avin_48040	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Avin_48050	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Avin_48060	COG0747	negative chemotaxis
Avin_48080	COG2177	Part of the ABC transporter FtsEX involved in
Avin_48090	COG2884	Cell division ATP-binding protein ftsE
Avin_48100	COG0552	protein localization to endoplasmic reticulum
Avin_48120	COG0584	glycerophosphoryl diester phosphodiesterase
Avin_48140	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Avin_48150	COG0697	spore germination
Avin_48160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Avin_48170	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Avin_48180	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Avin_48190	COG0730	response to heat
Avin_48220	COG3706	GGDEF domain
Avin_48230	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
Avin_48240	COG0494	nUDIX hydrolase
Avin_48270	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Avin_48280	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Avin_48300	COG0179	Fumarylacetoacetate (FAA) hydrolase
Avin_48310	COG0277	FAD linked oxidase domain protein
Avin_48330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Avin_48340	COG0679	Auxin Efflux Carrier
Avin_48350	COG3180	Ammonia monooxygenase
Avin_48440	COG0583	DNA-binding transcription factor activity
Avin_48450	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Avin_48510	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Avin_48540	COG1253	flavin adenine dinucleotide binding
Avin_48550	COG0739	heme binding
Avin_48580	COG0581	inorganic phosphate transmembrane transporter activity
Avin_48590	COG0573	inorganic phosphate transmembrane transporter activity
Avin_48610	COG1607	acyl-coa hydrolase
Avin_48620	COG0676	glucose-6-phosphate 1-epimerase activity
Avin_48690	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Avin_48730	COG1177	transmembrane transport
Avin_48740	COG1176	ABC-type spermidine putrescine transport system, permease component I
Avin_48750	COG3842	ATPase activity
Avin_48780	COG3547	Transposase (IS116 IS110 IS902 family)
Avin_48790	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
Avin_48840	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
Avin_48860	COG0174	glutamine synthetase
Avin_48870	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Avin_48880	COG0174	glutamine synthetase
Avin_48900	COG2957	Belongs to the agmatine deiminase family
Avin_48910	COG0640	Transcriptional regulator
Avin_48930	COG3706	GGDEF domain
Avin_49090	COG3909	cytochrome
Avin_49120	COG0667	Aldo Keto reductase
Avin_49180	COG0596	Alpha beta hydrolase
Avin_49290	COG1012	belongs to the aldehyde dehydrogenase family
Avin_49320	COG0165	Argininosuccinate lyase
Avin_49330	COG1301	dicarboxylic acid transport
Avin_49340	COG0583	DNA-binding transcription factor activity
Avin_49500	COG3180	Ammonia monooxygenase
Avin_49530	COG1024	Enoyl-CoA hydratase
Avin_49550	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Avin_49560	COG1960	acyl-CoA dehydrogenase activity
Avin_49570	COG0789	Transcriptional regulator
Avin_49590	COG2851	Citrate transporter
Avin_49600	COG0861	Integral membrane protein TerC family
Avin_49860	COG3293	Transposase
Avin_49900	COG0679	Auxin Efflux Carrier
Avin_49910	COG0149	triose-phosphate isomerase activity
Avin_49940	COG0697	spore germination
Avin_49960	COG0149	triose-phosphate isomerase activity
Avin_49970	COG0148	phosphopyruvate hydratase activity
Avin_50060	COG3718	enzyme involved in inositol metabolism
Avin_50070	COG2814	Major facilitator Superfamily
Avin_50070	COG0477	Major facilitator Superfamily
Avin_50100	COG3962	Belongs to the TPP enzyme family
Avin_50110	COG0673	inositol 2-dehydrogenase activity
Avin_50120	COG1082	Xylose isomerase domain protein TIM barrel
Avin_50130	COG1879	ABC-type sugar transport system periplasmic component
Avin_50200	COG0625	glutathione transferase activity
Avin_50220	COG1609	Transcriptional regulator
Avin_50260	COG0673	inositol 2-dehydrogenase activity
Avin_50270	COG4580	involved in the transport of maltose and maltodextrins
Avin_50300	COG1172	Belongs to the binding-protein-dependent transport system permease family
Avin_50310	COG1129	ABC transporter
Avin_50330	COG1120	ATPase activity
Avin_50340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Avin_50600	COG3415	Transposase
Avin_50600	COG2801	Transposase and inactivated derivatives
Avin_50630	COG0784	Response regulator, receiver
Avin_50630	COG5002	protein histidine kinase activity
Avin_50630	COG2205	protein histidine kinase activity
Avin_50640	COG3437	response regulator, receiver
Avin_50720	COG4149	molybdate abc transporter
Avin_50870	COG3501	Rhs element vgr protein
Avin_50920	COG2914	Belongs to the UPF0125 (RnfH) family
Avin_50930	COG4660	Part of a membrane complex involved in electron transport
Avin_50980	COG4657	Part of a membrane complex involved in electron transport
Avin_51060	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Avin_51080	COG3604	Transcriptional regulator
Avin_51100	COG1125	glycine betaine transport
Avin_51100	COG0517	IMP dehydrogenase activity
Avin_51110	COG2116	formate transmembrane transporter activity
Avin_51130	COG2271	Major facilitator Superfamily
Avin_51290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Avin_51310	COG2271	Major facilitator Superfamily
Avin_51320	COG4948	Mandelate Racemase Muconate Lactonizing
Avin_51330	COG0800	Aldolase
Avin_51350	COG1414	Transcriptional regulator
Avin_51390	COG4580	involved in the transport of maltose and maltodextrins
Avin_51400	COG2207	Transcriptional regulator
Avin_51420	COG1486	melibiose metabolic process
Avin_51430	COG2211	Major facilitator Superfamily
Avin_51450	COG3386	PFAM SMP-30 Gluconolaconase
Avin_51470	COG0366	Alpha amylase catalytic
Avin_51490	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Avin_51520	COG0667	Aldo Keto reductase
Avin_51560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Avin_51570	COG1538	Outer membrane efflux protein
Avin_51580	COG1250	3-hydroxyacyl-CoA dehydrogenase
Avin_51610	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
Avin_51670	COG0840	transmembrane signaling receptor activity
Avin_51690	COG2852	Protein conserved in bacteria
Avin_51700	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Avin_51710	COG1074	ATP-dependent DNA helicase activity
Avin_51720	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
Avin_51760	COG1272	protein, Hemolysin III
Avin_51780	COG1082	Xylose isomerase domain protein TIM barrel
Avin_51890	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Avin_51900	COG1349	DNA-binding transcription factor activity
Avin_51920	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Avin_51950	COG0601	transmembrane transport
Avin_51960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Avin_51970	COG4172	Belongs to the ABC transporter superfamily
Avin_52010	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Avin_52120	COG4771	TonB-dependent receptor
Avin_52150	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Avin_52160	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Avin_52170	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Avin_52180	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Avin_52190	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Avin_52200	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Avin_52220	COG0356	it plays a direct role in the translocation of protons across the membrane
Avin_52230	COG3312	ion transport
Avin_52240	COG1475	DNA binding
Avin_52250	COG1192	Involved in chromosome partitioning
Avin_52260	COG0357	Ribosomal RNA small subunit methyltransferase G
Avin_52270	COG0445	tRNA wobble uridine modification
Avin_52350	COG2189	Belongs to the N(4) N(6)-methyltransferase family
Avin_52390	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Avin_52450	COG0706	membrane insertase activity
Avin_52460	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Avin_52470	COG0594	ribonuclease P activity
Avin_52480	COG0230	Belongs to the bacterial ribosomal protein bL34 family