locus-tag	class	description
OE104_00005	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OE104_00010	COG1516	flagellar protein fliS
OE104_00030	COG2059	Chromate
OE104_00035	COG2059	Chromate
OE104_00050	COG0653	protein targeting
OE104_00065	COG2884	Cell division ATP-binding protein ftsE
OE104_00070	COG2177	Part of the ABC transporter FtsEX involved in
OE104_00075	COG0741	lytic transglycosylase activity
OE104_00075	COG1196	nuclear chromosome segregation
OE104_00075	COG0739	heme binding
OE104_00080	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OE104_00085	COG1131	(ABC) transporter
OE104_00090	COG0737	Belongs to the 5'-nucleotidase family
OE104_00095	COG0217	transcriptional regulatory protein
OE104_00100	COG0793	Belongs to the peptidase S41A family
OE104_00100	COG3409	Peptidoglycan-binding domain 1 protein
OE104_00105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OE104_00110	COG5522	Integral membrane protein (intg_mem_TP0381)
OE104_00125	COG2608	mercury ion transmembrane transporter activity
OE104_00130	COG2217	Heavy metal translocating P-type atpase
OE104_00180	COG1518	maintenance of DNA repeat elements
OE104_00185	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
OE104_00220	COG1337	RAMP superfamily
OE104_00255	COG4555	ABC transporter
OE104_00275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OE104_00285	COG1473	amidohydrolase
OE104_00290	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
OE104_00310	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
OE104_00335	COG1131	(ABC) transporter
OE104_00350	COG2814	Major facilitator Superfamily
OE104_00360	COG0789	Transcriptional regulator
OE104_00375	COG1876	peptidase activity
OE104_00380	COG1876	peptidase activity
OE104_00385	COG0546	phosphoglycolate phosphatase activity
OE104_00390	COG1349	DNA-binding transcription factor activity
OE104_00395	COG1105	Belongs to the carbohydrate kinase PfkB family
OE104_00400	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OE104_00400	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OE104_00400	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OE104_00405	COG0556	nucleotide-excision repair
OE104_00410	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OE104_00425	COG3595	metallopeptidase activity
OE104_00430	COG0363	glucosamine-6-phosphate deaminase activity
OE104_00435	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OE104_00440	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OE104_00450	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
OE104_00455	COG0546	phosphoglycolate phosphatase activity
OE104_00460	COG0110	maltose O-acetyltransferase activity
OE104_00465	COG0457	Tetratricopeptide repeat
OE104_00470	COG0492	ferredoxin-NADP+ reductase activity
OE104_00475	COG1051	belongs to the nudix hydrolase family
OE104_00480	COG1660	Displays ATPase and GTPase activities
OE104_00485	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OE104_00490	COG1481	regulation of sporulation
OE104_00495	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OE104_00500	COG0740	serine-type endopeptidase activity
OE104_00515	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
OE104_00525	COG2390	Transcriptional regulator
OE104_00535	COG0126	phosphoglycerate kinase activity
OE104_00540	COG0149	triose-phosphate isomerase activity
OE104_00545	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OE104_00550	COG0148	phosphopyruvate hydratase activity
OE104_00570	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OE104_00575	COG1647	Serine aminopeptidase, S33
OE104_00580	COG0557	exoribonuclease II activity
OE104_00585	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OE104_00600	COG0716	FMN binding
OE104_00610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OE104_00615	COG0765	amino acid transport
OE104_00660	COG0628	permease
OE104_00665	COG5577	PFAM Coat F domain
OE104_00675	COG0506	proline dehydrogenase activity
OE104_00680	COG1024	Enoyl-CoA hydratase
OE104_00680	COG1250	3-hydroxyacyl-CoA dehydrogenase
OE104_00685	COG0183	Belongs to the thiolase family
OE104_00690	COG1960	acyl-CoA dehydrogenase activity
OE104_00695	COG1393	Belongs to the ArsC family
OE104_00700	COG0509	glycine decarboxylation via glycine cleavage system
OE104_00705	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OE104_00710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OE104_00715	COG2814	Major facilitator Superfamily
OE104_00715	COG0477	Major facilitator Superfamily
OE104_00725	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OE104_00730	COG2011	ABC-type metal ion transport system permease component
OE104_00735	COG1464	Belongs to the NlpA lipoprotein family
OE104_00740	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OE104_00745	COG0396	ATPase activity
OE104_00750	COG0719	Fe-S assembly protein
OE104_00755	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OE104_00760	COG0822	iron-sulfur transferase activity
OE104_00765	COG0719	Fe-S assembly protein
OE104_00770	COG0737	Belongs to the 5'-nucleotidase family
OE104_00775	COG3377	Domain of unknown function (DUF1805)
OE104_00785	COG1757	Na H antiporter
OE104_00790	COG0733	neurotransmitter:sodium symporter activity
OE104_00800	COG0739	heme binding
OE104_00805	COG4470	Protein conserved in bacteria
OE104_00810	COG2445	Protein of unknown function DUF86
OE104_00815	COG0647	UMP catabolic process
OE104_00820	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OE104_00825	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OE104_00830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OE104_00840	COG4837	Protein of unknown function (DUF1462)
OE104_00845	COG1252	NADH dehydrogenase
OE104_00850	COG4844	belongs to the
OE104_00855	COG0316	Belongs to the HesB IscA family
OE104_00860	COG0492	ferredoxin-NADP+ reductase activity
OE104_00865	COG1252	NADH dehydrogenase
OE104_00880	COG3584	3D domain protein
OE104_00885	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OE104_00890	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OE104_00920	COG1131	(ABC) transporter
OE104_00955	COG2766	serine protein kinase
OE104_00975	COG3279	Response regulator of the LytR AlgR family
OE104_00980	COG2972	Histidine kinase
OE104_00980	COG0745	RESPONSE REGULATOR receiver
OE104_00990	COG2190	(PTS) system
OE104_00995	COG2718	Belongs to the UPF0229 family
OE104_01000	COG0366	Alpha amylase catalytic
OE104_01005	COG0366	Alpha amylase catalytic
OE104_01010	COG2814	Major facilitator Superfamily
OE104_01020	COG0039	L-malate dehydrogenase activity
OE104_01025	COG2252	PERMEase
OE104_01030	COG3396	Phenylacetate-CoA oxygenase
OE104_01045	COG2151	metal-sulfur cluster biosynthetic enzyme
OE104_01060	COG1024	Enoyl-CoA hydratase
OE104_01065	COG1250	3-hydroxyacyl-CoA dehydrogenase
OE104_01070	COG0183	Belongs to the thiolase family
OE104_01075	COG1024	Enoyl-CoA hydratase
OE104_01080	COG3327	negative regulation of DNA-templated transcription, initiation
OE104_01090	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OE104_01115	COG0681	Belongs to the peptidase S26 family
OE104_01125	COG0681	Belongs to the peptidase S26 family
OE104_01140	COG2986	histidine ammonia-lyase
OE104_01155	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OE104_01155	COG2111	Na H antiporter
OE104_01160	COG2111	Na H antiporter
OE104_01165	COG1006	Multisubunit Na H antiporter MnhC subunit
OE104_01170	COG0651	ATP synthesis coupled electron transport
OE104_01175	COG1863	multisubunit Na H antiporter MnhE subunit
OE104_01180	COG2212	antiporter activity
OE104_01185	COG1320	monovalent cation:proton antiporter activity
OE104_01190	COG2050	protein possibly involved in aromatic compounds catabolism
OE104_01195	COG2814	Major facilitator Superfamily
OE104_01200	COG0367	asparagine synthase
OE104_01215	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
OE104_01230	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OE104_01235	COG2155	Conserved Protein
OE104_01240	COG1979	alcohol dehydrogenase
OE104_01250	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OE104_01275	COG2197	response regulator
OE104_01280	COG4585	Histidine kinase
OE104_01285	COG0842	Transport permease protein
OE104_01290	COG1131	(ABC) transporter
OE104_01320	COG1285	pathogenesis
OE104_01325	COG0697	spore germination
OE104_01455	COG1575	Belongs to the MenA family. Type 1 subfamily
OE104_01460	COG1169	isochorismate synthase
OE104_01465	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
OE104_01470	COG0596	Alpha beta hydrolase
OE104_01475	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OE104_01480	COG0318	PFAM AMP-dependent synthetase and ligase
OE104_01490	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OE104_01495	COG0783	Belongs to the Dps family
OE104_01510	COG0494	nUDIX hydrolase
OE104_01515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OE104_01520	COG1116	anion transmembrane transporter activity
OE104_01525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OE104_01530	COG1506	peptidase
OE104_01545	COG4608	Belongs to the ABC transporter superfamily
OE104_01550	COG0601	transmembrane transport
OE104_01565	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OE104_01570	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OE104_01585	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OE104_01595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OE104_01600	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
OE104_01605	COG1242	4 iron, 4 sulfur cluster binding
OE104_01610	COG2814	Major facilitator Superfamily
OE104_01615	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OE104_01625	COG0495	leucyl-tRNA aminoacylation
OE104_01635	COG2081	HI0933 family
OE104_01640	COG2244	polysaccharide biosynthetic process
OE104_01650	COG1187	pseudouridine synthase activity
OE104_01655	COG1349	DNA-binding transcription factor activity
OE104_01660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OE104_01680	COG1597	lipid kinase activity
OE104_01685	COG0510	thiamine kinase activity
OE104_01695	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OE104_01700	COG0673	inositol 2-dehydrogenase activity
OE104_01705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OE104_01710	COG0697	spore germination
OE104_01720	COG1363	Peptidase, m42
OE104_01725	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
OE104_01735	COG0840	transmembrane signaling receptor activity
OE104_01740	COG4848	Belongs to the UPF0354 family
OE104_01745	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OE104_01750	COG1674	ftsk spoiiie
OE104_01760	COG4555	ABC transporter
OE104_01765	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OE104_01780	COG4980	gas vesicle protein
OE104_01785	COG3118	belongs to the thioredoxin family
OE104_01790	COG0849	cell division
OE104_01795	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
OE104_01795	COG1605	Chorismate mutase
OE104_01805	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OE104_01815	COG0123	including yeast histone deacetylase and acetoin utilization protein
OE104_01820	COG0517	IMP dehydrogenase activity
OE104_01825	COG0454	-acetyltransferase
OE104_01830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OE104_01845	COG0697	spore germination
OE104_01855	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
OE104_01860	COG1121	(ABC) transporter
OE104_01865	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OE104_01885	COG2357	RelA SpoT domain protein
OE104_01895	COG2514	catechol 2,3-dioxygenase activity
OE104_01910	COG1447	Phosphotransferase system cellobiose-specific component IIA
OE104_01915	COG2723	6-phospho-beta-galactosidase activity
OE104_01930	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OE104_01935	COG2723	6-phospho-beta-galactosidase activity
OE104_01940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OE104_01940	COG3711	transcriptional antiterminator
OE104_01955	COG0318	PFAM AMP-dependent synthetase and ligase
OE104_01960	COG1309	transcriptional regulator
OE104_01965	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OE104_01980	COG2199	diguanylate cyclase activity
OE104_01980	COG2203	Gaf domain
OE104_01985	COG1956	GAF domain-containing protein
OE104_01990	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
OE104_01995	COG1104	cysteine desulfurase activity
OE104_02000	COG0301	tRNA thio-modification
OE104_02025	COG2962	Rard protein
OE104_02030	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OE104_02035	COG0616	signal peptide processing
OE104_02040	COG1714	RDD family
OE104_02050	COG3874	Sporulation protein YtfJ
OE104_02055	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
OE104_02060	COG0827	DNA restriction-modification system
OE104_02065	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OE104_02075	COG0589	response to stress
OE104_02085	COG0006	proline dipeptidase activity
OE104_02090	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
OE104_02100	COG4109	DRTGG domain
OE104_02110	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
OE104_02125	COG0587	DNA-directed DNA polymerase activity
OE104_02130	COG1725	Transcriptional regulator
OE104_02135	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OE104_02140	COG0825	malonyl-CoA metabolic process
OE104_02145	COG0205	6-phosphofructokinase activity
OE104_02155	COG3030	protein affecting phage T7 exclusion by the F plasmid
OE104_02160	COG0628	permease
OE104_02165	COG0372	Belongs to the citrate synthase family
OE104_02170	COG0538	isocitrate dehydrogenase activity
OE104_02175	COG0039	L-malate dehydrogenase activity
OE104_02180	COG0745	RESPONSE REGULATOR receiver
OE104_02185	COG5002	protein histidine kinase activity
OE104_02195	COG0330	HflC and HflK could
OE104_02200	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OE104_02200	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OE104_02205	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OE104_02210	COG0237	dephospho-CoA kinase activity
OE104_02215	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OE104_02220	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OE104_02230	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OE104_02235	COG3611	Membrane attachment protein
OE104_02240	COG1484	DNA-dependent DNA replication
OE104_02250	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OE104_02265	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OE104_02270	COG3326	Membrane
OE104_02295	COG1132	(ABC) transporter
OE104_02305	COG1846	Transcriptional regulator
OE104_02310	COG1363	Peptidase, m42
OE104_02320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OE104_02325	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OE104_02330	COG0072	phenylalanine-tRNA ligase activity
OE104_02330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OE104_02335	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
OE104_02340	COG1286	toxin biosynthetic process
OE104_02345	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OE104_02345	COG1796	DNA polymerase
OE104_02350	COG1193	negative regulation of DNA recombination
OE104_02355	COG3766	membrane
OE104_02360	COG0318	PFAM AMP-dependent synthetase and ligase
OE104_02365	COG1309	transcriptional regulator
OE104_02370	COG1024	Enoyl-CoA hydratase
OE104_02375	COG2086	electron transfer activity
OE104_02380	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
OE104_02385	COG3118	belongs to the thioredoxin family
OE104_02390	COG0322	excinuclease ABC activity
OE104_02400	COG1719	4-vinyl reductase, 4VR
OE104_02405	COG2009	succinate dehydrogenase
OE104_02410	COG1053	succinate dehydrogenase
OE104_02415	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OE104_02425	COG2197	response regulator
OE104_02430	COG1846	Transcriptional regulator
OE104_02440	COG5401	PFAM Sporulation and spore germination
OE104_02445	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OE104_02450	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OE104_02455	COG0622	Phosphoesterase
OE104_02475	COG0544	peptidyl-prolyl cis-trans isomerase activity
OE104_02480	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OE104_02485	COG0470	DNA polymerase III
OE104_02485	COG1067	ATP-dependent peptidase activity
OE104_02490	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OE104_02495	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OE104_02510	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OE104_02515	COG0181	hydroxymethylbilane synthase activity
OE104_02525	COG0113	porphobilinogen synthase activity
OE104_02530	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OE104_02535	COG1388	LysM domain
OE104_02535	COG1388	LysM domain
OE104_02550	COG0525	valine-tRNA ligase activity
OE104_02555	COG0285	dihydrofolate synthase activity
OE104_02560	COG3706	GGDEF domain
OE104_02570	COG0424	maF-like protein
OE104_02575	COG2003	Belongs to the UPF0758 family
OE104_02580	COG1077	Cell shape determining protein MreB Mrl
OE104_02585	COG1792	Involved in formation and maintenance of cell shape
OE104_02595	COG0850	regulation of cytokinetic process
OE104_02600	COG2894	cell division
OE104_02610	COG1994	Peptidase M50
OE104_02615	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OE104_02620	COG2868	ribosomal protein
OE104_02625	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OE104_02630	COG3290	protein histidine kinase activity
OE104_02635	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OE104_02645	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OE104_02665	COG0632	four-way junction helicase activity
OE104_02670	COG2255	four-way junction helicase activity
OE104_02680	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OE104_02690	COG1862	Preprotein translocase
OE104_02700	COG2323	membrane
OE104_02705	COG2244	polysaccharide biosynthetic process
OE104_02715	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OE104_02715	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OE104_02720	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OE104_02720	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
OE104_02725	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OE104_02730	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OE104_02735	COG1490	D-aminoacyl-tRNA deacylase activity
OE104_02745	COG0124	histidyl-tRNA synthetase
OE104_02750	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OE104_02770	COG0840	transmembrane signaling receptor activity
OE104_02780	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OE104_02785	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OE104_02790	COG1959	2 iron, 2 sulfur cluster binding
OE104_02795	COG1104	cysteine desulfurase activity
OE104_02800	COG0482	sulfurtransferase activity
OE104_02805	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OE104_02815	COG0628	permease
OE104_02820	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OE104_02825	COG4472	Bacterial protein of unknown function (DUF965)
OE104_02830	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OE104_02835	COG3906	Belongs to the UPF0473 family
OE104_02840	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OE104_02845	COG4122	O-methyltransferase activity
OE104_02850	COG0826	peptidase U32
OE104_02855	COG0826	peptidase U32
OE104_02860	COG0572	uridine kinase
OE104_02865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OE104_02870	COG0768	penicillin binding
OE104_02880	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OE104_03000	COG3677	Transposase
OE104_03010	COG5484	DNA packaging
OE104_03040	COG2963	transposase activity
OE104_03045	COG2801	Transposase and inactivated derivatives
OE104_03145	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OE104_03160	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
OE104_03165	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OE104_03175	COG1534	Rna-binding protein
OE104_03180	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OE104_03185	COG1713	HD superfamily hydrolase involved in NAD metabolism
OE104_03190	COG0799	negative regulation of ribosome biogenesis
OE104_03195	COG2226	methyltransferase
OE104_03200	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OE104_03205	COG1555	photosystem II stabilization
OE104_03205	COG1596	polysaccharide export
OE104_03210	COG2131	deaminase
OE104_03215	COG2333	competence protein COMEC
OE104_03215	COG0658	competence protein
OE104_03225	COG1466	dna polymerase III delta subunit
OE104_03230	COG0268	Binds directly to 16S ribosomal RNA
OE104_03235	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
OE104_03245	COG0481	GTPase activity
OE104_03250	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OE104_03255	COG1420	regulation of RNA biosynthetic process
OE104_03260	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OE104_03265	COG0443	Heat shock 70 kDa protein
OE104_03270	COG0484	heat shock protein binding
OE104_03275	COG2264	protein methyltransferase activity
OE104_03280	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OE104_03285	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OE104_03290	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OE104_03295	COG1283	sodium-dependent phosphate transmembrane transporter activity
OE104_03300	COG0828	Belongs to the bacterial ribosomal protein bS21 family
OE104_03305	COG1610	YqeY-like protein
OE104_03310	COG1030	water channel activity
OE104_03335	COG1702	phosphate starvation-inducible protein PhoH
OE104_03340	COG1480	7TM receptor with intracellular HD hydrolase
OE104_03345	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OE104_03350	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OE104_03360	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OE104_03375	COG0752	glycyl-tRNA synthetase alpha subunit
OE104_03380	COG0751	glycine-tRNA ligase activity
OE104_03385	COG0517	IMP dehydrogenase activity
OE104_03390	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
OE104_03395	COG0358	DNA primase activity
OE104_03400	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OE104_03405	COG1960	acyl-CoA dehydrogenase activity
OE104_03410	COG2010	Cytochrome c
OE104_03415	COG2963	transposase activity
OE104_03420	COG2801	Transposase and inactivated derivatives
OE104_03425	COG2384	SAM-dependent methyltransferase
OE104_03430	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OE104_03435	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OE104_03445	COG0513	Belongs to the DEAD box helicase family
OE104_03450	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
OE104_03460	COG1121	(ABC) transporter
OE104_03465	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OE104_03470	COG0735	belongs to the Fur family
OE104_03475	COG4709	membrane
OE104_03480	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OE104_03490	COG0704	Plays a role in the regulation of phosphate uptake
OE104_03500	COG0477	Major facilitator Superfamily
OE104_03505	COG0768	penicillin binding
OE104_03525	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OE104_03530	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OE104_03540	COG0457	Tetratricopeptide repeat
OE104_03540	COG0705	Rhomboid family
OE104_03550	COG0697	spore germination
OE104_03555	COG4483	Protein conserved in bacteria
OE104_03560	COG1940	carbohydrate kinase activity
OE104_03565	COG1368	sulfuric ester hydrolase activity
OE104_03585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OE104_03610	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OE104_03615	COG1459	type II secretion system
OE104_03620	COG4537	Required for transformation and DNA binding
OE104_03660	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OE104_03665	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OE104_03670	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OE104_03675	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OE104_03680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OE104_03685	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OE104_03690	COG1752	Esterase of the alpha-beta hydrolase superfamily
OE104_03705	COG0006	proline dipeptidase activity
OE104_03710	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OE104_03720	COG3854	ATPases associated with a variety of cellular activities
OE104_03760	COG0511	ligase activity, forming carbon-carbon bonds
OE104_03765	COG0439	Biotin carboxylase
OE104_03770	COG1302	Protein conserved in bacteria
OE104_03775	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OE104_03780	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OE104_03785	COG1570	exodeoxyribonuclease VII activity
OE104_03790	COG1722	exodeoxyribonuclease VII activity
OE104_03795	COG0142	geranyltranstransferase activity
OE104_03805	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OE104_03810	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
OE104_03820	COG0497	DNA recombination
OE104_03825	COG0750	zinc metalloprotease
OE104_03830	COG0745	RESPONSE REGULATOR receiver
OE104_03835	COG0584	glycerophosphoryl diester phosphodiesterase
OE104_03845	COG3290	protein histidine kinase activity
OE104_03845	COG3829	transcription factor binding
OE104_03855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OE104_03860	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OE104_03865	COG0022	dehydrogenase e1 component
OE104_03870	COG0508	dehydrogenase complex catalyzes the overall conversion of
OE104_03890	COG1376	ErfK ybiS ycfS ynhG family protein
OE104_03900	COG0346	lactoylglutathione lyase activity
OE104_03905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OE104_03910	COG2195	Cleaves the N-terminal amino acid of tripeptides
OE104_03920	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OE104_03925	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OE104_03930	COG1234	tRNA 3'-trailer cleavage
OE104_03935	COG1902	pentaerythritol trinitrate reductase activity
OE104_03940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OE104_03945	COG0300	oxidoreductase activity
OE104_03970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OE104_03975	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OE104_03995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OE104_04010	COG0667	Aldo Keto reductase
OE104_04020	COG1379	DNA repair
OE104_04025	COG1300	Membrane
OE104_04030	COG0735	belongs to the Fur family
OE104_04040	COG4974	Belongs to the 'phage' integrase family
OE104_04055	COG1686	Belongs to the peptidase S11 family
OE104_04065	COG2172	sigma factor antagonist activity
OE104_04085	COG0697	spore germination
OE104_04100	COG1547	Domain of unknown function (DUF309)
OE104_04105	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OE104_04110	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OE104_04115	COG1686	Belongs to the peptidase S11 family
OE104_04120	COG2715	membrane protein required for spore maturation
OE104_04125	COG0700	Nucleoside recognition
OE104_04130	COG1187	pseudouridine synthase activity
OE104_04135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OE104_04140	COG1333	cytochrome c biogenesis protein
OE104_04145	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OE104_04150	COG0745	RESPONSE REGULATOR receiver
OE104_04155	COG5002	protein histidine kinase activity
OE104_04160	COG1595	DNA-templated transcription, initiation
OE104_04170	COG0739	heme binding
OE104_04175	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OE104_04180	COG1141	Ferredoxin
OE104_04190	COG0514	ATP-dependent DNA helicase (RecQ)
OE104_04195	COG1266	CAAX protease self-immunity
OE104_04210	COG4862	establishment of competence for transformation
OE104_04215	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OE104_04220	COG0492	ferredoxin-NADP+ reductase activity
OE104_04235	COG1175	transmembrane transport
OE104_04240	COG0395	ABC-type sugar transport system, permease component
OE104_04245	COG3842	ATPase activity
OE104_04250	COG2339	peptidase activity
OE104_04255	COG3409	Peptidoglycan-binding domain 1 protein
OE104_04255	COG3773	Cell wall hydrolase
OE104_04260	COG2959	enzyme of heme biosynthesis
OE104_04275	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OE104_04285	COG0539	negative regulation of cytoplasmic translation
OE104_04310	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OE104_04325	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OE104_04330	COG0776	regulation of translation
OE104_04335	COG0302	gtp cyclohydrolase
OE104_04345	COG0142	geranyltranstransferase activity
OE104_04350	COG2226	methyltransferase
OE104_04355	COG0142	geranyltranstransferase activity
OE104_04360	COG0105	UTP biosynthetic process
OE104_04365	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OE104_04370	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OE104_04375	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OE104_04390	COG0457	Tetratricopeptide repeat
OE104_04410	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OE104_04420	COG4347	Protein of unknown function (DUF1405)
OE104_04430	COG2738	Putative neutral zinc metallopeptidase
OE104_04435	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OE104_04440	COG1694	Mazg nucleotide pyrophosphohydrolase
OE104_04445	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OE104_04450	COG1803	Methylglyoxal synthase
OE104_04455	COG0438	transferase activity, transferring glycosyl groups
OE104_04460	COG0617	tRNA 3'-terminal CCA addition
OE104_04465	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
OE104_04465	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
OE104_04470	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
OE104_04475	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OE104_04480	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OE104_04495	COG0436	Aminotransferase
OE104_04500	COG0017	Asparaginyl-tRNA synthetase
OE104_04505	COG3935	DnaD domain protein
OE104_04510	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OE104_04520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OE104_04520	COG4499	WXG100 protein secretion system (Wss), protein YukC
OE104_04525	COG3331	DNA recombination
OE104_04550	COG1205	dead DEAH box helicase
OE104_04550	COG1111	helicase
OE104_04555	COG3359	exonuclease
OE104_04565	COG1612	heme a metabolic process
OE104_04580	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OE104_04585	COG1845	cytochrome c oxidase, subunit III
OE104_04595	COG3336	cytochrome c oxidase
OE104_04610	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
OE104_04615	COG2340	Cysteine-rich secretory protein family
OE104_04630	COG3679	Belongs to the UPF0342 family
OE104_04635	COG4471	UPF0298 protein
OE104_04645	COG0742	ribosomal rna small subunit methyltransferase
OE104_04650	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OE104_04655	COG3314	Sporulation integral membrane protein YlbJ
OE104_04660	COG1752	Esterase of the alpha-beta hydrolase superfamily
OE104_04665	COG3480	Lon protease (S16) C-terminal proteolytic domain
OE104_04670	COG1323	Belongs to the UPF0348 family
OE104_04675	COG1399	metal-binding, possibly nucleic acid-binding protein
OE104_04680	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OE104_04695	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OE104_04700	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OE104_04710	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
OE104_04720	COG0275	rRNA processing
OE104_04730	COG0768	penicillin binding
OE104_04735	COG0768	penicillin binding
OE104_04740	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OE104_04750	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OE104_04755	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OE104_04760	COG0772	Belongs to the SEDS family
OE104_04765	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OE104_04770	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OE104_04775	COG3879	Bacterial protein of unknown function (DUF881)
OE104_04780	COG3879	Bacterial protein of unknown function (DUF881)
OE104_04785	COG3856	small basic protein
OE104_04790	COG0849	cell division
OE104_04795	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OE104_04805	COG1191	sigma factor activity
OE104_04810	COG1191	sigma factor activity
OE104_04820	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OE104_04825	COG1799	cell septum assembly
OE104_04830	COG0762	integral membrane protein
OE104_04835	COG2302	S4 RNA-binding domain
OE104_04840	COG3599	regulation of cell shape
OE104_04845	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OE104_04850	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OE104_04855	COG0564	pseudouridine synthase activity
OE104_04860	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OE104_04865	COG1293	RNA-binding protein homologous to eukaryotic snRNP
OE104_04870	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OE104_04875	COG1561	YicC-like family, N-terminal region
OE104_04880	COG2052	Domain of unknown function (DUF370)
OE104_04885	COG0194	GDP metabolic process
OE104_04895	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OE104_04900	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OE104_04905	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OE104_04910	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OE104_04910	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OE104_04915	COG0631	protein serine/threonine phosphatase activity
OE104_04920	COG2815	serine threonine protein kinase
OE104_04920	COG0515	serine threonine protein kinase
OE104_04925	COG1162	GTPase activity
OE104_04930	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OE104_04935	COG1564	THIamine pyrophosphokinase
OE104_04945	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OE104_04950	COG1302	Protein conserved in bacteria
OE104_04955	COG1461	Dihydroxyacetone kinase
OE104_04960	COG1760	l-serine dehydratase
OE104_04965	COG1760	l-serine dehydratase
OE104_04970	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OE104_04975	COG1349	DNA-binding transcription factor activity
OE104_04980	COG0416	fatty acid biosynthetic process
OE104_04985	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OE104_04990	COG1028	Short-chain dehydrogenase reductase Sdr
OE104_04995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OE104_05000	COG0571	ribonuclease III activity
OE104_05005	COG1196	nuclear chromosome segregation
OE104_05010	COG0552	protein localization to endoplasmic reticulum
OE104_05020	COG1131	(ABC) transporter
OE104_05035	COG0714	Associated with various cellular activities
OE104_05060	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
OE104_05065	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OE104_05070	COG0228	four-way junction DNA binding
OE104_05075	COG1837	Belongs to the UPF0109 family
OE104_05085	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OE104_05090	COG0336	Belongs to the RNA methyltransferase TrmD family
OE104_05095	COG0335	large ribosomal subunit rRNA binding
OE104_05105	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OE104_05110	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OE104_05120	COG2257	FlhB HrpN YscU SpaS Family
OE104_05125	COG0045	succinate-CoA ligase (ADP-forming) activity
OE104_05130	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OE104_05135	COG0758	DNA mediated transformation
OE104_05140	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OE104_05145	COG4974	Belongs to the 'phage' integrase family
OE104_05150	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OE104_05155	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OE104_05160	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OE104_05165	COG1815	bacterial-type flagellum-dependent cell motility
OE104_05170	COG1558	bacterial-type flagellum-dependent cell motility
OE104_05175	COG1677	Flagellar hook-basal body complex protein FliE
OE104_05180	COG1766	The M ring may be actively involved in energy transduction
OE104_05185	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OE104_05190	COG1317	bacterial-type flagellum organization
OE104_05195	COG1157	protein secretion by the type III secretion system
OE104_05200	COG2882	bacterial-type flagellum organization
OE104_05215	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
OE104_05225	COG1749	Flagellar hook protein flgE
OE104_05230	COG1582	Flagellar protein (FlbD)
OE104_05235	COG1580	Controls the rotational direction of flagella during chemotaxis
OE104_05240	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OE104_05245	COG1776	CheC inhibitor of MCP methylation
OE104_05245	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OE104_05250	COG2201	protein-glutamate methylesterase activity
OE104_05255	COG3190	flagellar
OE104_05260	COG1338	Plays a role in the flagellum-specific transport system
OE104_05265	COG1987	bacterial-type flagellum assembly
OE104_05270	COG1684	flagellar biosynthetic protein fliR
OE104_05275	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OE104_05280	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OE104_05285	COG1419	protein localization to endoplasmic reticulum
OE104_05290	COG0455	bacterial-type flagellum organization
OE104_05295	COG2201	protein-glutamate methylesterase activity
OE104_05300	COG2198	Histidine kinase
OE104_05300	COG0643	Histidine kinase
OE104_05305	COG0835	chemotaxis
OE104_05310	COG1776	CheC inhibitor of MCP methylation
OE104_05315	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
OE104_05320	COG1191	sigma factor activity
OE104_05335	COG0052	Belongs to the universal ribosomal protein uS2 family
OE104_05340	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OE104_05350	COG0233	cytoplasmic translational termination
OE104_05355	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OE104_05360	COG4589	Belongs to the CDS family
OE104_05370	COG0750	zinc metalloprotease
OE104_05375	COG0442	prolyl-tRNA aminoacylation
OE104_05380	COG2176	DNA-directed DNA polymerase activity
OE104_05385	COG0779	Required for maturation of 30S ribosomal subunits
OE104_05390	COG0195	Participates in both transcription termination and antitermination
OE104_05395	COG2740	Nucleic-acid-binding protein implicated in transcription termination
OE104_05400	COG1358	cellular component organization or biogenesis
OE104_05410	COG1550	Protein conserved in bacteria
OE104_05415	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OE104_05420	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OE104_05425	COG0196	riboflavin kinase activity
OE104_05430	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OE104_05435	COG1185	polyribonucleotide nucleotidyltransferase activity
OE104_05440	COG0726	polysaccharide deacetylase
OE104_05445	COG0612	Peptidase, M16
OE104_05450	COG1873	PFAM PRC-barrel domain
OE104_05455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OE104_05460	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OE104_05465	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OE104_05470	COG0527	aspartate kinase activity
OE104_05475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OE104_05480	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OE104_05485	COG0740	serine-type endopeptidase activity
OE104_05495	COG4980	gas vesicle protein
OE104_05495	COG1674	ftsk spoiiie
OE104_05500	COG1744	ABC transporter substrate-binding protein PnrA-like
OE104_05505	COG3845	ABC transporter
OE104_05510	COG4603	Belongs to the binding-protein-dependent transport system permease family
OE104_05515	COG1079	Belongs to the binding-protein-dependent transport system permease family
OE104_05520	COG0612	Peptidase, M16
OE104_05525	COG0612	Peptidase, M16
OE104_05530	COG0300	oxidoreductase activity
OE104_05545	COG1426	Protein conserved in bacteria
OE104_05550	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OE104_05555	COG1058	Belongs to the CinA family
OE104_05555	COG1546	Belongs to the CinA family
OE104_05575	COG0674	pyruvate-flavodoxin oxidoreductase activity
OE104_05585	COG0446	pyridine nucleotide-disulphide oxidoreductase
OE104_05595	COG1533	DNA photolyase activity
OE104_05605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OE104_05615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OE104_05625	COG1418	mRNA catabolic process
OE104_05630	COG1692	metallophosphoesterase
OE104_05635	COG2359	stage V sporulation protein S
OE104_05650	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OE104_05655	COG4550	Control of competence regulator ComK, YlbF/YmcA
OE104_05660	COG1408	metallophosphoesterase
OE104_05670	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OE104_05675	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OE104_05680	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OE104_05685	COG1923	regulation of RNA biosynthetic process
OE104_05690	COG0464	growth
OE104_05700	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
OE104_05705	COG0789	Transcriptional regulator
OE104_05710	COG0174	glutamine synthetase
OE104_05715	COG0582	viral genome integration into host DNA
OE104_05730	COG3617	BRO family, N-terminal domain
OE104_05785	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
OE104_05805	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OE104_05940	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OE104_05945	COG4224	UPF0291 protein
OE104_05960	COG3763	UPF0154 protein
OE104_05980	COG1132	(ABC) transporter
OE104_05985	COG1132	(ABC) transporter
OE104_05990	COG0785	Cytochrome C biogenesis protein
OE104_05995	COG2201	protein-glutamate methylesterase activity
OE104_06025	COG0668	transmembrane transport
OE104_06035	COG1607	acyl-coa hydrolase
OE104_06040	COG0519	Catalyzes the synthesis of GMP from XMP
OE104_06045	COG1301	dicarboxylic acid transport
OE104_06055	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OE104_06060	COG1960	acyl-CoA dehydrogenase activity
OE104_06065	COG0436	Aminotransferase
OE104_06090	COG1733	regulation of RNA biosynthetic process
OE104_06100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OE104_06105	COG2358	TRAP transporter, solute receptor (TAXI family
OE104_06120	COG0561	phosphatase activity
OE104_06135	COG4948	Mandelate Racemase Muconate Lactonizing
OE104_06140	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OE104_06160	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OE104_06180	COG0824	Thioesterase
OE104_06215	COG0860	N-Acetylmuramoyl-L-alanine amidase
OE104_06220	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OE104_06230	COG1832	CoA-binding protein
OE104_06235	COG0187	DNA topoisomerase II activity
OE104_06240	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OE104_06245	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
OE104_06250	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
OE104_06270	COG0318	PFAM AMP-dependent synthetase and ligase
OE104_06275	COG0471	metal ion transport
OE104_06275	COG0490	domain, Protein
OE104_06280	COG1090	epimerase
OE104_06290	COG0420	3'-5' exonuclease activity
OE104_06295	COG2176	DNA-directed DNA polymerase activity
OE104_06305	COG0004	ammonium transporteR
OE104_06315	COG0671	phosphoesterase, PA-phosphatase related
OE104_06320	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OE104_06330	COG2814	Major facilitator Superfamily
OE104_06345	COG0175	sulfate reduction
OE104_06350	COG2046	Belongs to the sulfate adenylyltransferase family
OE104_06355	COG0529	Catalyzes the synthesis of activated sulfate
OE104_06360	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OE104_06370	COG1368	sulfuric ester hydrolase activity
OE104_06375	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OE104_06380	COG0798	PFAM Bile acid sodium symporter
OE104_06385	COG0640	Transcriptional regulator
OE104_06390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OE104_06395	COG4129	membrane
OE104_06400	COG0542	response to heat
OE104_06405	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
OE104_06420	COG0179	Fumarylacetoacetate (FAA) hydrolase
OE104_06425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OE104_06450	COG0583	DNA-binding transcription factor activity
OE104_06455	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OE104_06460	COG0783	Belongs to the Dps family
OE104_06465	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OE104_06475	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OE104_06480	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
OE104_06485	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
OE104_06485	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OE104_06485	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OE104_06490	COG1461	Dihydroxyacetone kinase
OE104_06495	COG2376	Dihydroxyacetone kinase
OE104_06500	COG3829	transcription factor binding
OE104_06500	COG3290	protein histidine kinase activity
OE104_06515	COG1132	(ABC) transporter
OE104_06520	COG0789	Transcriptional regulator
OE104_06535	COG0385	Bile acid
OE104_06545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OE104_06550	COG3223	Belongs to the PsiE family
OE104_06565	COG1309	transcriptional regulator
OE104_06570	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OE104_06575	COG5564	TIM-barrel signal transduction protein
OE104_06585	COG5564	TIM-barrel signal transduction protein
OE104_06595	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OE104_06600	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OE104_06600	COG0140	phosphoribosyl-ATP diphosphatase activity
OE104_06605	COG0107	imidazoleglycerol-phosphate synthase activity
OE104_06610	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OE104_06615	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OE104_06620	COG0131	Imidazoleglycerol-phosphate dehydratase
OE104_06630	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OE104_06635	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
OE104_06640	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OE104_06665	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
OE104_06685	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OE104_06695	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OE104_06710	COG1074	ATP-dependent DNA helicase activity
OE104_06715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OE104_06725	COG1131	(ABC) transporter
OE104_06735	COG0789	Transcriptional regulator
OE104_06760	COG0277	FAD linked oxidase domain protein
OE104_06775	COG4989	oxidoreductase activity
OE104_06780	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OE104_06785	COG1028	Short-chain dehydrogenase reductase Sdr
OE104_06810	COG1307	EDD domain protein, DegV family
OE104_06825	COG0708	Exodeoxyribonuclease III
OE104_06830	COG1067	ATP-dependent peptidase activity
OE104_06835	COG3341	Caulimovirus viroplasmin
OE104_06835	COG0328	RNA-DNA hybrid ribonuclease activity
OE104_06845	COG0494	nUDIX hydrolase
OE104_06860	COG1132	(ABC) transporter
OE104_06865	COG1132	(ABC) transporter
OE104_06870	COG0604	alcohol dehydrogenase
OE104_06875	COG1132	(ABC) transporter
OE104_06880	COG1132	(ABC) transporter
OE104_06885	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OE104_06895	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OE104_06905	COG1854	S-ribosylhomocysteine lyase activity
OE104_06910	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OE104_06920	COG5002	protein histidine kinase activity
OE104_06930	COG0745	RESPONSE REGULATOR receiver
OE104_06935	COG0726	polysaccharide deacetylase
OE104_06940	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OE104_06960	COG1268	BioY protein
OE104_06970	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OE104_06975	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OE104_06985	COG2151	metal-sulfur cluster biosynthetic enzyme
OE104_06990	COG0508	dehydrogenase complex catalyzes the overall conversion of
OE104_06995	COG0567	Dehydrogenase, E1 component
OE104_07000	COG1278	Cold shock
OE104_07010	COG1404	Belongs to the peptidase S8 family
OE104_07010	COG4412	M6 family metalloprotease domain protein
OE104_07015	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OE104_07020	COG1793	dna ligase
OE104_07020	COG3285	dna ligase
OE104_07025	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OE104_07030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OE104_07045	COG0534	Mate efflux family protein
OE104_07050	COG1028	Short-chain dehydrogenase reductase Sdr
OE104_07065	COG0793	Belongs to the peptidase S41A family
OE104_07065	COG3409	Peptidoglycan-binding domain 1 protein
OE104_07070	COG1876	peptidase activity
OE104_07085	COG4479	Belongs to the UPF0346 family
OE104_07090	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OE104_07095	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OE104_07100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OE104_07100	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
OE104_07105	COG4698	Protein conserved in bacteria
OE104_07110	COG2755	lipolytic protein G-D-S-L family
OE104_07115	COG1999	signal sequence binding
OE104_07125	COG2135	peptidase activity
OE104_07130	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OE104_07135	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OE104_07155	COG1413	lyase activity
OE104_07160	COG0488	(ABC) transporter
OE104_07165	COG2963	transposase activity
OE104_07170	COG2801	Transposase and inactivated derivatives
OE104_07185	COG1321	iron dependent repressor
OE104_07190	COG1278	Cold shock
OE104_07205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OE104_07215	COG2233	PERMEase
OE104_07220	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OE104_07225	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
OE104_07230	COG0697	spore germination
OE104_07235	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OE104_07245	COG0116	Belongs to the methyltransferase superfamily
OE104_07255	COG3599	regulation of cell shape
OE104_07260	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
OE104_07265	COG0772	Belongs to the SEDS family
OE104_07270	COG4838	Belongs to the UPF0358 family
OE104_07275	COG2066	Belongs to the glutaminase family
OE104_07280	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OE104_07290	COG4896	Protein conserved in bacteria
OE104_07300	COG1217	gtp-binding protein TYPA
OE104_07310	COG0483	inositol monophosphate 1-phosphatase activity
OE104_07315	COG4493	Belongs to the UPF0637 family
OE104_07320	COG4476	Belongs to the UPF0223 family
OE104_07345	COG0022	dehydrogenase e1 component
OE104_07365	COG0561	phosphatase activity
OE104_07375	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OE104_07380	COG0569	domain protein
OE104_07385	COG1132	(ABC) transporter
OE104_07390	COG1132	(ABC) transporter
OE104_07395	COG1473	amidohydrolase
OE104_07400	COG2171	N-acyltransferase activity
OE104_07405	COG0583	DNA-binding transcription factor activity
OE104_07410	COG0517	IMP dehydrogenase activity
OE104_07415	COG4703	Protein of unknown function (DUF1797)
OE104_07425	COG1408	metallophosphoesterase
OE104_07435	COG0835	chemotaxis
OE104_07440	COG0436	Aminotransferase
OE104_07450	COG2084	Dehydrogenase
OE104_07460	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OE104_07475	COG3773	Cell wall hydrolase
OE104_07480	COG4873	Protein conserved in bacteria
OE104_07490	COG3949	Membrane
OE104_07495	COG0542	response to heat
OE104_07505	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OE104_07510	COG5002	protein histidine kinase activity
OE104_07520	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OE104_07530	COG0861	Integral membrane protein TerC family
OE104_07535	COG1309	transcriptional regulator
OE104_07545	COG0372	Belongs to the citrate synthase family
OE104_07550	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OE104_07555	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OE104_07565	COG1121	(ABC) transporter
OE104_07575	COG0579	oxidoreductase
OE104_07580	COG1126	abc transporter atp-binding protein
OE104_07585	COG0765	amino acid transport
OE104_07590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OE104_07595	COG2207	Transcriptional regulator
OE104_07615	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
OE104_07620	COG0655	NAD(P)H dehydrogenase (quinone) activity
OE104_07625	COG2814	Major facilitator Superfamily
OE104_07630	COG0003	Pfam Anion-transporting ATPase
OE104_07640	COG1966	Carbon starvation protein
OE104_07650	COG0426	domain, Protein
OE104_07650	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OE104_07660	COG2076	Multidrug Resistance protein
OE104_07665	COG2076	Multidrug Resistance protein
OE104_07670	COG1733	regulation of RNA biosynthetic process
OE104_07685	COG0095	Lipoate-protein ligase
OE104_07695	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OE104_07700	COG0656	L-ascorbic acid biosynthetic process
OE104_07710	COG0058	SHG alpha-glucan phosphorylase activity
OE104_07715	COG0297	glycogen (starch) synthase activity
OE104_07720	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OE104_07725	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OE104_07730	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OE104_07735	COG1523	belongs to the glycosyl hydrolase 13 family
OE104_07740	COG0693	protein deglycase activity
OE104_07750	COG1228	amidohydrolase
OE104_07785	COG2963	transposase activity
OE104_07790	COG2801	Transposase and inactivated derivatives
OE104_07795	COG0438	transferase activity, transferring glycosyl groups
OE104_07800	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OE104_07810	COG0366	Alpha amylase catalytic
OE104_07815	COG0395	ABC-type sugar transport system, permease component
OE104_07820	COG1175	transmembrane transport
OE104_07830	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
OE104_07835	COG1609	Transcriptional regulator
OE104_07840	COG0726	polysaccharide deacetylase
OE104_07880	COG0583	DNA-binding transcription factor activity
OE104_07890	COG0010	Belongs to the arginase family
OE104_07895	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OE104_07900	COG1228	amidohydrolase
OE104_07905	COG3314	Sporulation integral membrane protein YlbJ
OE104_07920	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OE104_07980	COG0577	efflux transmembrane transporter activity
OE104_07985	COG1136	(ABC) transporter
OE104_07990	COG1063	alcohol dehydrogenase
OE104_08005	COG1131	(ABC) transporter
OE104_08010	COG2211	Major facilitator Superfamily
OE104_08065	COG1489	DNA binding
OE104_08085	COG1309	transcriptional regulator
OE104_08090	COG2313	pseudouridylate synthase activity
OE104_08095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OE104_08095	COG1522	sequence-specific DNA binding
OE104_08100	COG1331	Highly conserved protein containing a thioredoxin domain
OE104_08110	COG1388	LysM domain
OE104_08110	COG3858	chitin binding
OE104_08140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OE104_08145	COG4841	protein insertion into membrane
OE104_08165	COG3180	Ammonia monooxygenase
OE104_08170	COG1114	Component of the transport system for branched-chain amino acids
OE104_08175	COG1227	inorganic diphosphatase activity
OE104_08180	COG2996	Protein conserved in bacteria
OE104_08190	COG2382	esterase
OE104_08195	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OE104_08200	COG2153	protein acetylation
OE104_08205	COG2323	membrane
OE104_08230	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OE104_08265	COG0475	glutathione-regulated potassium exporter activity
OE104_08265	COG0569	domain protein
OE104_08285	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OE104_08290	COG0564	pseudouridine synthase activity
OE104_08300	COG2357	RelA SpoT domain protein
OE104_08305	COG4116	CYTH
OE104_08310	COG0741	lytic transglycosylase activity
OE104_08315	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OE104_08325	COG1164	Oligoendopeptidase f
OE104_08335	COG4862	establishment of competence for transformation
OE104_08340	COG1393	Belongs to the ArsC family
OE104_08350	COG0180	Tryptophanyl-tRNA synthetase
OE104_08355	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OE104_08370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OE104_08375	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OE104_08390	COG2267	carboxylic ester hydrolase activity
OE104_08400	COG2801	Transposase and inactivated derivatives
OE104_08405	COG2963	transposase activity
OE104_08415	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OE104_08420	COG4565	transcriptional regulatory protein
OE104_08425	COG3290	protein histidine kinase activity
OE104_08430	COG2151	metal-sulfur cluster biosynthetic enzyme
OE104_08435	COG1073	alpha beta
OE104_08440	COG0561	phosphatase activity
OE104_08450	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OE104_08455	COG1307	EDD domain protein, DegV family
OE104_08470	COG1554	hydrolase, family 65, central catalytic
OE104_08475	COG0366	Alpha amylase catalytic
OE104_08475	COG1874	Beta-galactosidase
OE104_08480	COG3833	ABC-type maltose transport systems, permease component
OE104_08485	COG1175	transmembrane transport
OE104_08490	COG2182	Extracellular solute-binding protein
OE104_08500	COG5278	phosphoserine phosphatase activity
OE104_08500	COG0840	transmembrane signaling receptor activity
OE104_08515	COG2311	Membrane
OE104_08555	COG1074	ATP-dependent DNA helicase activity
OE104_08560	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
OE104_08565	COG2814	Major facilitator Superfamily
OE104_08570	COG0398	Pfam SNARE associated Golgi protein
OE104_08575	COG0823	Involved in the tonB-independent uptake of proteins
OE104_08575	COG1506	peptidase
OE104_08575	COG4946	Tricorn protease homolog
OE104_08585	COG4903	ComK protein
OE104_08595	COG0501	Belongs to the peptidase M48B family
OE104_08615	COG0095	Lipoate-protein ligase
OE104_08620	COG1234	tRNA 3'-trailer cleavage
OE104_08630	COG2963	transposase activity
OE104_08635	COG2801	Transposase and inactivated derivatives
OE104_08640	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OE104_08645	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OE104_08655	COG1473	amidohydrolase
OE104_08660	COG4473	ABC transporter
OE104_08665	COG1131	(ABC) transporter
OE104_08670	COG0537	adenosine 5'-monophosphoramidase activity
OE104_08680	COG1846	Transcriptional regulator
OE104_08705	COG2801	Transposase and inactivated derivatives
OE104_08710	COG2963	transposase activity
OE104_08715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OE104_08725	COG3481	metal-dependent phosphohydrolase, HD sub domain
OE104_08730	COG4717	serine-type aminopeptidase activity
OE104_08735	COG0420	3'-5' exonuclease activity
OE104_08740	COG1668	transmembrane transport
OE104_08745	COG4152	abc transporter atp-binding protein
OE104_08755	COG1252	NADH dehydrogenase
OE104_08765	COG0561	phosphatase activity
OE104_08775	COG4399	Belongs to the UPF0754 family
OE104_08785	COG0189	ligase activity
OE104_08790	COG1937	Protein conserved in bacteria
OE104_08795	COG2508	Transcriptional regulator
OE104_08800	COG3842	ATPase activity
OE104_08810	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OE104_08815	COG4191	Histidine kinase
OE104_08820	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OE104_08825	COG2814	Major facilitator Superfamily
OE104_08845	COG1131	(ABC) transporter
OE104_08850	COG2197	response regulator
OE104_08860	COG0701	Predicted permease
OE104_08870	COG2719	SpoVR family
OE104_08875	COG1028	Short-chain dehydrogenase reductase Sdr
OE104_08880	COG0493	'glutamate synthase
OE104_08885	COG0069	glutamate synthase activity
OE104_08885	COG0067	glutamate synthase
OE104_08885	COG0070	glutamate synthase
OE104_08890	COG0583	DNA-binding transcription factor activity
OE104_08895	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OE104_08910	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
OE104_08915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OE104_08920	COG0564	pseudouridine synthase activity
OE104_08925	COG0656	L-ascorbic acid biosynthetic process
OE104_08930	COG0318	PFAM AMP-dependent synthetase and ligase
OE104_08935	COG1028	Short-chain dehydrogenase reductase Sdr
OE104_08955	COG0559	Belongs to the binding-protein-dependent transport system permease family
OE104_08965	COG0411	ABC transporter
OE104_08985	COG1737	Transcriptional regulator
OE104_08990	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OE104_08995	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OE104_09000	COG2706	6-phosphogluconolactonase activity
OE104_09005	COG2329	Antibiotic biosynthesis monooxygenase
OE104_09010	COG4607	ABC-type enterochelin transport system periplasmic component
OE104_09015	COG4604	ABC transporter, ATP-binding protein
OE104_09020	COG4605	iron ion homeostasis
OE104_09025	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OE104_09135	COG0735	belongs to the Fur family
OE104_09145	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OE104_09150	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OE104_09160	COG4129	membrane
OE104_09165	COG3557	Belongs to the UPF0374 family
OE104_09180	COG1988	membrane-bound metal-dependent
OE104_09185	COG2801	Transposase and inactivated derivatives
OE104_09190	COG2963	transposase activity
OE104_09200	COG2137	regulation of response to DNA damage stimulus
OE104_09210	COG1253	flavin adenine dinucleotide binding
OE104_09215	COG1115	amino acid carrier protein
OE104_09220	COG1757	Na H antiporter
OE104_09250	COG1012	belongs to the aldehyde dehydrogenase family
OE104_09260	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OE104_09265	COG4988	ABC transporter
OE104_09270	COG1294	oxidase, subunit
OE104_09275	COG1271	oxidase subunit
OE104_09285	COG0710	3-dehydroquinate dehydratase activity
OE104_09290	COG0840	transmembrane signaling receptor activity
OE104_09295	COG1174	glycine betaine transport
OE104_09305	COG1174	glycine betaine transport
OE104_09310	COG0517	IMP dehydrogenase activity
OE104_09310	COG1125	glycine betaine transport
OE104_09315	COG1510	regulation of RNA biosynthetic process
OE104_09325	COG3869	Catalyzes the specific phosphorylation of arginine residues in
OE104_09330	COG3880	PFAM UvrB UvrC protein
OE104_09335	COG2207	Transcriptional regulator
OE104_09365	COG0105	UTP biosynthetic process
OE104_09455	COG2801	Transposase and inactivated derivatives
OE104_09465	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OE104_09470	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OE104_09475	COG2270	Major facilitator Superfamily
OE104_09480	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OE104_09505	COG1595	DNA-templated transcription, initiation
OE104_09510	COG2814	Major facilitator Superfamily
OE104_09550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OE104_09560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OE104_09570	COG0084	hydrolase, TatD family'
OE104_09585	COG0745	RESPONSE REGULATOR receiver
OE104_09590	COG5002	protein histidine kinase activity
OE104_09590	COG3850	Histidine kinase
OE104_09595	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OE104_09600	COG0577	efflux transmembrane transporter activity
OE104_09600	COG1136	(ABC) transporter
OE104_09605	COG0577	efflux transmembrane transporter activity
OE104_09605	COG1136	(ABC) transporter
OE104_09610	COG4260	virion core protein, lumpy skin disease virus
OE104_09615	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OE104_09620	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OE104_09625	COG1842	Phage shock protein A
OE104_09650	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OE104_09660	COG1459	type II secretion system
OE104_09685	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
OE104_09695	COG1733	regulation of RNA biosynthetic process
OE104_09705	COG0778	Nitroreductase
OE104_09710	COG2723	6-phospho-beta-galactosidase activity
OE104_09715	COG2190	(PTS) system
OE104_09715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OE104_09715	COG1263	PTS System
OE104_09725	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OE104_09745	COG1929	Belongs to the glycerate kinase type-1 family
OE104_09750	COG1737	Transcriptional regulator
OE104_09755	COG1486	melibiose metabolic process
OE104_09770	COG0306	phosphate transporter
OE104_09780	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OE104_09780	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OE104_09780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OE104_09785	COG0789	Transcriptional regulator
OE104_09790	COG0300	oxidoreductase activity
OE104_09795	COG3711	transcriptional antiterminator
OE104_09795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OE104_09800	COG3773	Cell wall hydrolase
OE104_09815	COG1136	(ABC) transporter
OE104_09895	COG0366	Alpha amylase catalytic
OE104_09905	COG1501	Belongs to the glycosyl hydrolase 31 family
OE104_09910	COG1653	transport
OE104_09970	COG1131	(ABC) transporter
OE104_09985	COG1396	sequence-specific DNA binding
OE104_10030	COG1609	Transcriptional regulator
OE104_10035	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OE104_10040	COG0800	Aldolase
OE104_10045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OE104_10065	COG1028	Short-chain dehydrogenase reductase Sdr
OE104_10070	COG0477	Major facilitator Superfamily
OE104_10085	COG1595	DNA-templated transcription, initiation
OE104_10110	COG1012	belongs to the aldehyde dehydrogenase family
OE104_10115	COG0840	transmembrane signaling receptor activity
OE104_10120	COG0386	Belongs to the glutathione peroxidase family
OE104_10140	COG0726	polysaccharide deacetylase
OE104_10165	COG3711	transcriptional antiterminator
OE104_10170	COG0450	alkyl hydroperoxide reductase
OE104_10175	COG3634	alkyl hydroperoxide reductase activity
OE104_10180	COG0494	nUDIX hydrolase
OE104_10195	COG1395	domain, Protein
OE104_10225	COG2197	response regulator
OE104_10230	COG4585	Histidine kinase
OE104_10250	COG1051	belongs to the nudix hydrolase family
OE104_10265	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OE104_10265	COG0456	acetyltransferase
OE104_10270	COG3385	transposase activity
OE104_10315	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OE104_10335	COG2217	Heavy metal translocating P-type atpase
OE104_10340	COG1295	ribonuclease BN
OE104_10350	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OE104_10360	COG0024	Methionine aminopeptidase
OE104_10380	COG1115	amino acid carrier protein
OE104_10390	COG2309	aminopeptidase activity
OE104_10395	COG0393	Putative heavy-metal-binding
OE104_10400	COG2963	transposase activity
OE104_10405	COG2801	Transposase and inactivated derivatives
OE104_10410	COG2244	polysaccharide biosynthetic process
OE104_10415	COG1882	Formate acetyltransferase
OE104_10420	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
OE104_10425	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
OE104_10430	COG2186	Transcriptional regulator
OE104_10435	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OE104_10470	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
OE104_10470	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OE104_10475	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
OE104_10480	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OE104_10485	COG1012	belongs to the aldehyde dehydrogenase family
OE104_10490	COG1126	abc transporter atp-binding protein
OE104_10495	COG0765	amino acid transport
OE104_10500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OE104_10545	COG2268	Band 7 protein
OE104_10550	COG1585	Membrane protein implicated in regulation of membrane protease activity
OE104_10565	COG0534	Mate efflux family protein
OE104_10570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OE104_10575	COG1321	iron dependent repressor
OE104_10575	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OE104_10580	COG1121	(ABC) transporter
OE104_10585	COG0803	Belongs to the bacterial solute-binding protein 9 family
OE104_10595	COG0640	Transcriptional regulator
OE104_10605	COG5001	Diguanylate cyclase
OE104_10605	COG3300	MHYT domain
OE104_10615	COG1012	belongs to the aldehyde dehydrogenase family
OE104_10615	COG1454	alcohol dehydrogenase
OE104_10640	COG2966	Psort location CytoplasmicMembrane, score
OE104_10665	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OE104_10675	COG1272	protein, Hemolysin III
OE104_10690	COG0109	protoheme IX farnesyltransferase activity
OE104_10700	COG0561	phosphatase activity
OE104_10705	COG0745	RESPONSE REGULATOR receiver
OE104_10710	COG0642	Histidine kinase
OE104_10715	COG1136	(ABC) transporter
OE104_10720	COG0577	efflux transmembrane transporter activity
OE104_10730	COG0583	DNA-binding transcription factor activity
OE104_10745	COG0562	UDP-galactopyranose mutase
OE104_10750	COG1216	Glycosyl transferase, family 2
OE104_10765	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OE104_10780	COG0697	spore germination
OE104_10790	COG1073	alpha beta
OE104_10795	COG1215	transferase activity, transferring glycosyl groups
OE104_10800	COG5298	Protein conserved in bacteria
OE104_10815	COG0778	Nitroreductase
OE104_10820	COG1846	Transcriptional regulator
OE104_10835	COG3706	GGDEF domain
OE104_10845	COG2315	Protein conserved in bacteria
OE104_10850	COG1131	(ABC) transporter
OE104_10855	COG1725	Transcriptional regulator
OE104_10870	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
OE104_10875	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
OE104_10880	COG3775	system Galactitol-specific IIC component
OE104_10885	COG3414	Phosphotransferase system galactitol-specific IIB component
OE104_10900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OE104_10900	COG3711	transcriptional antiterminator
OE104_10915	COG3655	Transcriptional regulator
OE104_10925	COG2814	Major facilitator Superfamily
OE104_10930	COG1309	transcriptional regulator
OE104_10935	COG2188	Transcriptional regulator
OE104_10950	COG1454	alcohol dehydrogenase
OE104_10970	COG2356	endonuclease I
OE104_10975	COG2226	methyltransferase
OE104_11025	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OE104_11030	COG3716	PTS system mannose fructose sorbose family IID component
OE104_11040	COG0371	Dehydrogenase
OE104_11045	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OE104_11050	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
OE104_11055	COG1737	Transcriptional regulator
OE104_11060	COG0561	phosphatase activity
OE104_11065	COG0800	Aldolase
OE104_11070	COG1063	alcohol dehydrogenase
OE104_11075	COG0589	response to stress
OE104_11080	COG0659	secondary active sulfate transmembrane transporter activity
OE104_11095	COG0534	Mate efflux family protein
OE104_11110	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OE104_11125	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OE104_11230	COG0765	amino acid transport
OE104_11235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OE104_11285	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
OE104_11300	COG0395	ABC-type sugar transport system, permease component
OE104_11330	COG2814	Major facilitator Superfamily
OE104_11340	COG2801	Transposase and inactivated derivatives
OE104_11360	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OE104_11365	COG1597	lipid kinase activity
OE104_11380	COG0318	PFAM AMP-dependent synthetase and ligase
OE104_11385	COG1960	acyl-CoA dehydrogenase activity
OE104_11395	COG2801	Transposase and inactivated derivatives
OE104_11400	COG2963	transposase activity
OE104_11405	COG1012	belongs to the aldehyde dehydrogenase family
OE104_11410	COG2819	hydrolase of the alpha beta superfamily
OE104_11415	COG2207	Transcriptional regulator
OE104_11415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OE104_11420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OE104_11425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OE104_11430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OE104_11435	COG1120	ATPase activity
OE104_11455	COG0154	amidase activity
OE104_11460	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OE104_11465	COG5506	Protein of unknown function (DUF1694)
OE104_11470	COG1012	belongs to the aldehyde dehydrogenase family
OE104_11480	COG4851	CamS sex pheromone cAM373 precursor
OE104_11490	COG0210	DNA helicase
OE104_11500	COG4496	protein, YerC YecD
OE104_11505	COG1470	cell adhesion involved in biofilm formation
OE104_11510	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OE104_11535	COG0395	ABC-type sugar transport system, permease component
OE104_11540	COG1175	transmembrane transport
OE104_11550	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OE104_11555	COG1263	PTS System
OE104_11555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OE104_11555	COG2190	(PTS) system
OE104_11560	COG3711	transcriptional antiterminator
OE104_11565	COG2252	PERMEase
OE104_11570	COG0519	Catalyzes the synthesis of GMP from XMP
OE104_11570	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OE104_11580	COG0745	RESPONSE REGULATOR receiver
OE104_11585	COG5002	protein histidine kinase activity
OE104_11590	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OE104_11595	COG0463	Glycosyl transferase, family 2
OE104_11600	COG2246	polysaccharide biosynthetic process
OE104_11605	COG1305	Transglutaminase-like
OE104_11610	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
OE104_11615	COG0714	Associated with various cellular activities
OE104_11625	COG0114	fumarate hydratase activity
OE104_11630	COG0551	DNA topoisomerase type I activity
OE104_11630	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OE104_11665	COG0110	maltose O-acetyltransferase activity
OE104_11670	COG1164	Oligoendopeptidase f
OE104_11680	COG0459	protein refolding
OE104_11690	COG1266	CAAX protease self-immunity
OE104_11700	COG0805	protein transport
OE104_11705	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OE104_11710	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OE104_11715	COG0488	(ABC) transporter
OE104_11720	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OE104_11725	COG0456	acetyltransferase
OE104_11730	COG1214	PFAM Peptidase M22, glycoprotease
OE104_11735	COG0802	atpase or kinase
OE104_11785	COG3091	SprT-like family
OE104_11795	COG2183	response to ionizing radiation
OE104_11800	COG2337	Toxic component of a toxin-antitoxin (TA) module
OE104_11805	COG0864	Transcriptional regulator
OE104_11815	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OE104_11820	COG0736	holo-[acyl-carrier-protein] synthase activity
OE104_11830	COG3428	Bacterial PH domain
OE104_11835	COG3402	PFAM membrane-flanked domain
OE104_11840	COG4294	response to UV
OE104_11845	COG0513	Belongs to the DEAD box helicase family
OE104_11855	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OE104_11870	COG2239	Acts as a magnesium transporter
OE104_11875	COG1253	flavin adenine dinucleotide binding
OE104_11880	COG0772	Belongs to the SEDS family
OE104_11885	COG3853	Toxic anion resistance protein (TelA)
OE104_11890	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
OE104_11895	COG1136	(ABC) transporter
OE104_11905	COG1879	ABC-type sugar transport system periplasmic component
OE104_11910	COG1172	Belongs to the binding-protein-dependent transport system permease family
OE104_11915	COG1129	ABC transporter
OE104_11925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OE104_11930	COG1609	Transcriptional regulator
OE104_11940	COG1609	Transcriptional regulator
OE104_11950	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
OE104_11955	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OE104_11960	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OE104_11990	COG2972	Histidine kinase
OE104_11995	COG4753	response regulator
OE104_11995	COG2207	Transcriptional regulator
OE104_11995	COG4753	response regulator
OE104_11995	COG2207	Transcriptional regulator
OE104_12005	COG1175	transmembrane transport
OE104_12015	COG4753	response regulator
OE104_12015	COG2207	Transcriptional regulator
OE104_12020	COG2972	Histidine kinase
OE104_12035	COG1136	(ABC) transporter
OE104_12040	COG1940	carbohydrate kinase activity
OE104_12045	COG1482	cell wall glycoprotein biosynthetic process
OE104_12065	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OE104_12075	COG0673	inositol 2-dehydrogenase activity
OE104_12085	COG0235	Class ii aldolase
OE104_12095	COG3775	system Galactitol-specific IIC component
OE104_12100	COG3414	Phosphotransferase system galactitol-specific IIB component
OE104_12105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OE104_12115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OE104_12120	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OE104_12125	COG4145	pantothenate transmembrane transporter activity
OE104_12140	COG0444	Belongs to the ABC transporter superfamily
OE104_12145	COG4608	Belongs to the ABC transporter superfamily
OE104_12150	COG0747	negative chemotaxis
OE104_12155	COG0601	transmembrane transport
OE104_12160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OE104_12165	COG1686	Belongs to the peptidase S11 family
OE104_12170	COG0840	transmembrane signaling receptor activity
OE104_12175	COG0840	transmembrane signaling receptor activity
OE104_12190	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
OE104_12195	COG1177	transmembrane transport
OE104_12200	COG1176	ABC-type spermidine putrescine transport system, permease component I
OE104_12215	COG0840	transmembrane signaling receptor activity
OE104_12220	COG5002	protein histidine kinase activity
OE104_12220	COG3850	Histidine kinase
OE104_12225	COG0745	RESPONSE REGULATOR receiver
OE104_12265	COG0733	neurotransmitter:sodium symporter activity
OE104_12270	COG2223	nitrite transmembrane transporter activity
OE104_12275	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OE104_12280	COG1140	nitrate reductase beta subunit
OE104_12285	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
OE104_12290	COG2181	nitrate reductase activity
OE104_12300	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OE104_12305	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OE104_12310	COG0303	'Molybdopterin
OE104_12315	COG0314	molybdopterin synthase activity
OE104_12320	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OE104_12325	COG1763	Mo-molybdopterin cofactor biosynthetic process
OE104_12330	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OE104_12335	COG0746	molybdenum cofactor guanylyltransferase activity
OE104_12340	COG0521	Mo-molybdopterin cofactor biosynthetic process
OE104_12345	COG0725	ABC transporter, periplasmic molybdate-binding protein
OE104_12350	COG4149	molybdate abc transporter
OE104_12355	COG0315	cyclic pyranopterin monophosphate synthase activity
OE104_12365	COG2340	Cysteine-rich secretory protein family
OE104_12370	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OE104_12375	COG0142	geranyltranstransferase activity
OE104_12390	COG1846	Transcriptional regulator
OE104_12400	COG0730	response to heat
OE104_12405	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OE104_12410	COG0390	transport system, permease component
OE104_12415	COG0628	permease
OE104_12445	COG0840	transmembrane signaling receptor activity
OE104_12455	COG3775	system Galactitol-specific IIC component
OE104_12460	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OE104_12465	COG3414	Phosphotransferase system galactitol-specific IIB component
OE104_12470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OE104_12470	COG3711	transcriptional antiterminator
OE104_12475	COG3739	integral membrane protein
OE104_12480	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OE104_12490	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OE104_12505	COG1959	2 iron, 2 sulfur cluster binding
OE104_12545	COG1725	Transcriptional regulator
OE104_12550	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OE104_12555	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OE104_12560	COG4856	YbbR-like protein
OE104_12565	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OE104_12570	COG5662	AntiSigma factor
OE104_12575	COG1595	DNA-templated transcription, initiation
OE104_12655	COG0726	polysaccharide deacetylase
OE104_12660	COG2194	sulfuric ester hydrolase activity
OE104_12670	COG0489	protein tyrosine kinase activity
OE104_12675	COG0860	N-Acetylmuramoyl-L-alanine amidase
OE104_12690	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OE104_12705	COG1609	Transcriptional regulator
OE104_12710	COG1280	lysine exporter protein (LysE YggA)
OE104_12720	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OE104_12725	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OE104_12730	COG0101	tRNA pseudouridine synthase activity
OE104_12735	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OE104_12745	COG1122	ATPase activity
OE104_12750	COG0203	ribosomal protein L17
OE104_12755	COG0202	RNA polymerase activity
OE104_12760	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OE104_12765	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OE104_12770	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OE104_12775	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OE104_12780	COG2163	COG2163 Ribosomal protein L14E L6E L27E
OE104_12785	COG0563	adenylate kinase activity
OE104_12790	COG0201	protein transport
OE104_12795	COG0200	Binds to the 23S rRNA
OE104_12800	COG1841	ribosomal large subunit assembly
OE104_12805	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OE104_12810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OE104_12815	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OE104_12820	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OE104_12825	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OE104_12830	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OE104_12840	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OE104_12850	COG0255	Belongs to the universal ribosomal protein uL29 family
OE104_12855	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OE104_12860	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OE104_12870	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OE104_12875	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OE104_12880	COG0089	rRNA binding
OE104_12890	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OE104_12895	COG0051	transcription antitermination factor activity, RNA binding
OE104_12900	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OE104_12905	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OE104_12910	COG0049	tRNA binding
OE104_12915	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OE104_12920	COG1358	cellular component organization or biogenesis
OE104_12925	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OE104_12930	COG0085	RNA polymerase activity
OE104_12935	COG2813	Specifically methylates the guanine in position
OE104_12940	COG0222	ribosome binding
OE104_12950	COG0081	regulation of translation
OE104_12955	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OE104_12960	COG0250	Participates in transcription elongation, termination and antitermination
OE104_12965	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OE104_12975	COG3688	RNA-binding protein containing a PIN domain
OE104_12980	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OE104_12990	COG0215	cysteine-tRNA ligase activity
OE104_12995	COG1045	serine acetyltransferase
OE104_13000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OE104_13015	COG4956	integral membrane protein (PIN domain superfamily)
OE104_13020	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OE104_13025	COG0542	response to heat
OE104_13030	COG3869	Catalyzes the specific phosphorylation of arginine residues in
OE104_13035	COG3880	PFAM UvrB UvrC protein
OE104_13130	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OE104_13135	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OE104_13140	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OE104_13145	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OE104_13150	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OE104_13155	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OE104_13165	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OE104_13170	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
OE104_13175	COG0037	tRNA processing
OE104_13180	COG0515	serine threonine protein kinase
OE104_13185	COG2304	oxidoreductase activity
OE104_13190	COG2208	phosphoserine phosphatase activity
OE104_13195	COG1098	S1 RNA binding domain
OE104_13215	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OE104_13220	COG3956	TIGRFAM MazG family protein
OE104_13225	COG2244	polysaccharide biosynthetic process
OE104_13230	COG2002	toxin-antitoxin pair type II binding
OE104_13235	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OE104_13245	COG0193	aminoacyl-tRNA hydrolase activity
OE104_13255	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OE104_13260	COG2088	sporulation resulting in formation of a cellular spore
OE104_13265	COG0251	oxidation-reduction process
OE104_13270	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OE104_13290	COG4466	Protein conserved in bacteria
OE104_13300	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OE104_13305	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OE104_13310	COG3584	3D domain protein
OE104_13310	COG3583	domain protein
OE104_13315	COG0084	hydrolase, TatD family'
OE104_13325	COG2002	toxin-antitoxin pair type II binding
OE104_13330	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OE104_13340	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
OE104_13345	COG4467	Involved in initiation control of chromosome replication
OE104_13350	COG1774	PSP1 C-terminal conserved region
OE104_13355	COG0470	DNA polymerase III
OE104_13360	COG1728	Protein conserved in bacteria
OE104_13365	COG3870	Protein conserved in bacteria
OE104_13370	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OE104_13420	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OE104_13425	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OE104_13430	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OE104_13445	COG1131	(ABC) transporter
OE104_13460	COG0590	tRNA wobble adenosine to inosine editing
OE104_13465	COG1388	LysM domain
OE104_13465	COG3858	chitin binding
OE104_13470	COG1428	Deoxynucleoside kinase
OE104_13475	COG1428	Deoxynucleoside kinase
OE104_13480	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OE104_13490	COG0517	IMP dehydrogenase activity
OE104_13490	COG0516	GMP reductase activity
OE104_13505	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OE104_13510	COG0187	DNA topoisomerase II activity
OE104_13520	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OE104_13525	COG2501	S4 domain
OE104_13530	COG0592	DNA-directed DNA polymerase activity
OE104_13535	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OE104_13540	COG0230	Belongs to the bacterial ribosomal protein bL34 family
OE104_13545	COG0594	ribonuclease P activity
OE104_13550	COG0706	membrane insertase activity
OE104_13555	COG1847	R3H domain protein
OE104_13560	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OE104_13565	COG0445	tRNA wobble uridine modification
OE104_13575	COG1475	DNA binding
OE104_13580	COG1192	Involved in chromosome partitioning
OE104_13585	COG1475	DNA binding
OE104_13600	COG4481	Protein conserved in bacteria
OE104_13605	COG0012	GTP binding
OE104_13610	COG0360	Binds together with S18 to 16S ribosomal RNA
OE104_13620	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OE104_13625	COG4241	membrane
OE104_13635	COG0359	binds to the 23S rRNA
OE104_13640	COG0305	Participates in initiation and elongation during chromosome replication
OE104_13650	COG1196	nuclear chromosome segregation
OE104_13650	COG0741	lytic transglycosylase activity
OE104_13650	COG0739	heme binding
OE104_13655	COG0745	RESPONSE REGULATOR receiver
OE104_13660	COG5002	protein histidine kinase activity
OE104_13665	COG4863	YycH protein
OE104_13680	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
OE104_13685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OE104_13695	COG0454	-acetyltransferase
OE104_13700	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OE104_13715	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OE104_13735	COG0446	pyridine nucleotide-disulphide oxidoreductase
OE104_13745	COG0745	RESPONSE REGULATOR receiver
OE104_13750	COG5002	protein histidine kinase activity
OE104_13765	COG5337	Spore coat protein CotH
OE104_13775	COG0517	IMP dehydrogenase activity
OE104_13775	COG1125	glycine betaine transport
OE104_13780	COG1174	glycine betaine transport
OE104_13790	COG0739	heme binding
OE104_13795	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OE104_13800	COG4492	Belongs to the UPF0735 family
OE104_13855	COG0753	catalase activity
OE104_13860	COG2195	Cleaves the N-terminal amino acid of tripeptides
OE104_13865	COG1442	glycosyl transferase family 8
OE104_13870	COG0444	Belongs to the ABC transporter superfamily
OE104_13875	COG4608	Belongs to the ABC transporter superfamily
OE104_13880	COG0747	negative chemotaxis
OE104_13885	COG0601	transmembrane transport
OE104_13890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OE104_13895	COG0589	response to stress
OE104_13900	COG1253	flavin adenine dinucleotide binding
OE104_13910	COG0427	acetyl-CoA hydrolase
OE104_13915	COG3279	Response regulator of the LytR AlgR family
OE104_13920	COG0156	8-amino-7-oxononanoate synthase activity
OE104_13925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OE104_13930	COG1725	Transcriptional regulator
OE104_13950	COG3314	Sporulation integral membrane protein YlbJ
OE104_13965	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OE104_13970	COG0351	phosphomethylpyrimidine kinase
OE104_14005	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OE104_14015	COG2363	Small membrane protein
OE104_14025	COG3253	May function as heme-dependent peroxidase
OE104_14030	COG0280	phosphate acetyltransferase
OE104_14035	COG0095	Lipoate-protein ligase
OE104_14045	COG4844	belongs to the
OE104_14050	COG1078	dGTPase activity
OE104_14055	COG3465	dGTPase activity
OE104_14060	COG1994	Peptidase M50
OE104_14075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OE104_14085	COG0018	arginyl-trna synthetase
OE104_14090	COG2181	nitrate reductase activity
OE104_14090	COG0247	lactate metabolic process
OE104_14095	COG0183	Belongs to the thiolase family
OE104_14100	COG1250	3-hydroxyacyl-CoA dehydrogenase
OE104_14105	COG1960	acyl-CoA dehydrogenase activity
OE104_14110	COG1960	acyl-CoA dehydrogenase activity
OE104_14120	COG1703	isobutyryl-CoA mutase activity
OE104_14120	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OE104_14120	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OE104_14130	COG3343	RNA polymerase activity
OE104_14135	COG0504	CTP synthase activity
OE104_14140	COG4821	SIS domain
OE104_14145	COG2204	response regulator
OE104_14150	COG0191	fructose-bisphosphate aldolase activity
OE104_14155	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OE104_14160	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OE104_14165	COG1494	fructose-1,6-bisphosphatase
OE104_14170	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OE104_14175	COG0254	rRNA binding
OE104_14180	COG1435	thymidine kinase activity
OE104_14185	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OE104_14190	COG2890	protein-(glutamine-N5) methyltransferase activity
OE104_14200	COG0009	L-threonylcarbamoyladenylate synthase
OE104_14205	COG1971	Probably functions as a manganese efflux pump
OE104_14215	COG0840	transmembrane signaling receptor activity
OE104_14220	COG0698	ribose 5-phosphate isomerase
OE104_14225	COG4475	Protein of unknown function (DUF436)
OE104_14230	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OE104_14235	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OE104_14240	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
OE104_14245	COG1404	Belongs to the peptidase S8 family
OE104_14255	COG0356	it plays a direct role in the translocation of protons across the membrane
OE104_14260	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OE104_14265	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OE104_14270	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OE104_14275	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OE104_14280	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OE104_14285	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OE104_14290	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OE104_14305	COG0649	NAD binding
OE104_14305	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OE104_14315	COG4836	Membrane
OE104_14325	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OE104_14330	COG2385	sporulation resulting in formation of a cellular spore
OE104_14340	COG0739	heme binding
OE104_14345	COG1609	Transcriptional regulator
OE104_14355	COG4786	Flagellar basal body rod
OE104_14360	COG4786	Flagellar basal body rod
OE104_14385	COG0629	single-stranded DNA binding
OE104_14395	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OE104_14400	COG4715	Zinc finger, swim domain protein
OE104_14405	COG0671	phosphoesterase, PA-phosphatase related
OE104_14420	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OE104_14425	COG1368	sulfuric ester hydrolase activity
OE104_14460	COG0445	tRNA wobble uridine modification
OE104_14465	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
OE104_14470	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OE104_14495	COG1682	transport, permease protein
OE104_14500	COG1134	teichoic acid transport
OE104_14510	COG3944	biosynthesis protein
OE104_14515	COG0489	protein tyrosine kinase activity
OE104_14520	COG4464	protein tyrosine phosphatase activity
OE104_14525	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OE104_14540	COG0562	UDP-galactopyranose mutase
OE104_14565	COG2046	Belongs to the sulfate adenylyltransferase family
OE104_14570	COG0471	metal ion transport
OE104_14570	COG3273	potassium ion transport
OE104_14575	COG0529	Catalyzes the synthesis of activated sulfate
OE104_14585	COG1316	TRANSCRIPTIONal
OE104_14600	COG5492	domain, Protein
OE104_14635	COG0737	Belongs to the 5'-nucleotidase family
OE104_14640	COG0737	Belongs to the 5'-nucleotidase family
OE104_14645	COG0704	Plays a role in the regulation of phosphate uptake
OE104_14655	COG0581	inorganic phosphate transmembrane transporter activity
OE104_14660	COG0573	inorganic phosphate transmembrane transporter activity
OE104_14665	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OE104_14675	COG3958	Transketolase
OE104_14680	COG3959	Transketolase, thiamine diphosphate binding domain
OE104_14695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OE104_14720	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OE104_14730	COG0318	PFAM AMP-dependent synthetase and ligase
OE104_14740	COG1024	Enoyl-CoA hydratase
OE104_14750	COG1309	transcriptional regulator
OE104_14765	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OE104_14775	COG0460	homoserine dehydrogenase
OE104_14780	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OE104_14815	COG1024	Enoyl-CoA hydratase
OE104_14820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OE104_14820	COG1263	PTS System
OE104_14825	COG3711	transcriptional antiterminator
OE104_14830	COG1263	PTS System
OE104_14830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OE104_14830	COG2190	(PTS) system
OE104_14845	COG1554	hydrolase, family 65, central catalytic
OE104_14855	COG1175	transmembrane transport
OE104_14860	COG0395	ABC-type sugar transport system, permease component
OE104_14865	COG1609	Transcriptional regulator
OE104_14870	COG0071	Belongs to the small heat shock protein (HSP20) family
OE104_14875	COG1254	Belongs to the acylphosphatase family
OE104_14880	COG1316	TRANSCRIPTIONal
OE104_14890	COG3764	Sortase (surface protein transpeptidase)
OE104_14895	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OE104_14900	COG1316	TRANSCRIPTIONal
OE104_14905	COG1739	Uncharacterized protein family UPF0029
OE104_14910	COG1309	transcriptional regulator
OE104_14915	COG1511	domain protein
OE104_14920	COG2801	Transposase and inactivated derivatives
OE104_14925	COG2963	transposase activity
OE104_14930	COG1063	alcohol dehydrogenase
OE104_14935	COG1396	sequence-specific DNA binding
OE104_14940	COG4585	Histidine kinase
OE104_14945	COG2197	response regulator
OE104_14950	COG1307	EDD domain protein, DegV family
OE104_14955	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
OE104_14960	COG1040	competence protein
OE104_14970	COG2747	anti-sigma28 factor FlgM
OE104_14980	COG1256	bacterial-type flagellum assembly
OE104_14980	COG4786	Flagellar basal body rod
OE104_14985	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OE104_14995	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
OE104_15000	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OE104_15005	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OE104_15025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OE104_15030	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OE104_15035	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
OE104_15040	COG2089	acid synthase
OE104_15050	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OE104_15055	COG1083	cytidylyl-transferase
OE104_15060	COG2807	transmembrane transport
OE104_15065	COG1334	flagellar protein FlaG