locus-tag	class	description
OE105_00015	COG1266	CAAX protease self-immunity
OE105_00025	COG0459	protein refolding
OE105_00030	COG1164	Oligoendopeptidase f
OE105_00060	COG2814	Major facilitator Superfamily
OE105_00075	COG0114	fumarate hydratase activity
OE105_00085	COG0714	Associated with various cellular activities
OE105_00090	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
OE105_00095	COG1305	Transglutaminase-like
OE105_00100	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OE105_00100	COG0519	Catalyzes the synthesis of GMP from XMP
OE105_00105	COG2252	PERMEase
OE105_00110	COG3711	transcriptional antiterminator
OE105_00115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OE105_00115	COG1263	PTS System
OE105_00115	COG2190	(PTS) system
OE105_00125	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OE105_00135	COG4974	Belongs to the 'phage' integrase family
OE105_00145	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OE105_00150	COG1470	cell adhesion involved in biofilm formation
OE105_00155	COG4496	protein, YerC YecD
OE105_00160	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
OE105_00165	COG0210	DNA helicase
OE105_00175	COG4851	CamS sex pheromone cAM373 precursor
OE105_00180	COG1012	belongs to the aldehyde dehydrogenase family
OE105_00185	COG5506	Protein of unknown function (DUF1694)
OE105_00190	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OE105_00195	COG0154	amidase activity
OE105_00210	COG1301	dicarboxylic acid transport
OE105_00215	COG0069	glutamate synthase activity
OE105_00235	COG1597	lipid kinase activity
OE105_00245	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OE105_00250	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OE105_00270	COG3328	transposase activity
OE105_00280	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
OE105_00290	COG3464	Transposase
OE105_00335	COG3850	Histidine kinase
OE105_00335	COG5002	protein histidine kinase activity
OE105_00340	COG0577	efflux transmembrane transporter activity
OE105_00345	COG1136	(ABC) transporter
OE105_00370	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OE105_00395	COG4372	Transposase
OE105_00440	COG2184	nucleotidyltransferase activity
OE105_00470	COG0726	polysaccharide deacetylase
OE105_00475	COG4555	ABC transporter
OE105_00520	COG4585	Histidine kinase
OE105_00545	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OE105_00580	COG1063	alcohol dehydrogenase
OE105_00615	COG2226	methyltransferase
OE105_00620	COG2356	endonuclease I
OE105_00630	COG4443	Transcriptional Coactivator p15 (PC4)
OE105_00645	COG1309	transcriptional regulator
OE105_00650	COG2814	Major facilitator Superfamily
OE105_00660	COG3655	Transcriptional regulator
OE105_00670	COG3711	transcriptional antiterminator
OE105_00670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OE105_00685	COG3414	Phosphotransferase system galactitol-specific IIB component
OE105_00690	COG3775	system Galactitol-specific IIC component
OE105_00700	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
OE105_00705	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
OE105_00710	COG1012	belongs to the aldehyde dehydrogenase family
OE105_00725	COG1725	Transcriptional regulator
OE105_00730	COG1131	(ABC) transporter
OE105_00735	COG1846	Transcriptional regulator
OE105_00740	COG0778	Nitroreductase
OE105_00750	COG1073	alpha beta
OE105_00760	COG0697	spore germination
OE105_00785	COG0463	Glycosyl transferase, family 2
OE105_00790	COG0562	UDP-galactopyranose mutase
OE105_00800	COG0583	DNA-binding transcription factor activity
OE105_00810	COG0577	efflux transmembrane transporter activity
OE105_00815	COG1136	(ABC) transporter
OE105_00820	COG2205	protein histidine kinase activity
OE105_00825	COG0745	RESPONSE REGULATOR receiver
OE105_00830	COG0561	phosphatase activity
OE105_00840	COG0109	protoheme IX farnesyltransferase activity
OE105_00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OE105_00860	COG1272	protein, Hemolysin III
OE105_00870	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OE105_00890	COG2966	Psort location CytoplasmicMembrane, score
OE105_00915	COG1454	alcohol dehydrogenase
OE105_00915	COG1012	belongs to the aldehyde dehydrogenase family
OE105_00920	COG1405	negative regulation of cell septum assembly
OE105_00920	COG3012	SEC-C Motif Domain Protein
OE105_00925	COG3706	GGDEF domain
OE105_00925	COG4251	negative regulation of phosphorylation
OE105_00925	COG5001	Diguanylate cyclase
OE105_00925	COG2203	Gaf domain
OE105_00935	COG3706	GGDEF domain
OE105_00940	COG0640	Transcriptional regulator
OE105_00950	COG0803	Belongs to the bacterial solute-binding protein 9 family
OE105_00955	COG1121	(ABC) transporter
OE105_00960	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OE105_00960	COG1321	iron dependent repressor
OE105_00965	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OE105_00975	COG0534	Mate efflux family protein
OE105_00990	COG1585	Membrane protein implicated in regulation of membrane protease activity
OE105_00995	COG2268	Band 7 protein
OE105_01030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OE105_01035	COG0765	amino acid transport
OE105_01040	COG1126	abc transporter atp-binding protein
OE105_01045	COG5505	Protein of unknown function (DUF819)
OE105_01050	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
OE105_01055	COG1882	Formate acetyltransferase
OE105_01060	COG2244	polysaccharide biosynthetic process
OE105_01065	COG0393	Putative heavy-metal-binding
OE105_01070	COG2309	aminopeptidase activity
OE105_01080	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OE105_01085	COG1840	ABC-type Fe3 transport system, periplasmic component
OE105_01090	COG4149	molybdate abc transporter
OE105_01100	COG1115	amino acid carrier protein
OE105_01120	COG0024	Methionine aminopeptidase
OE105_01130	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OE105_01140	COG1295	ribonuclease BN
OE105_01145	COG2217	Heavy metal translocating P-type atpase
OE105_01170	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OE105_01195	COG3142	Participates in the control of copper homeostasis
OE105_01235	COG4974	Belongs to the 'phage' integrase family
OE105_01240	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OE105_01245	COG1131	(ABC) transporter
OE105_01265	COG1131	(ABC) transporter
OE105_01280	COG1395	domain, Protein
OE105_01285	COG3634	alkyl hydroperoxide reductase activity
OE105_01290	COG0450	alkyl hydroperoxide reductase
OE105_01305	COG0726	polysaccharide deacetylase
OE105_01320	COG0386	Belongs to the glutathione peroxidase family
OE105_01325	COG0840	transmembrane signaling receptor activity
OE105_01330	COG1012	belongs to the aldehyde dehydrogenase family
OE105_01375	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
OE105_01435	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OE105_01445	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
OE105_01470	COG1459	type II secretion system
OE105_01480	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OE105_01505	COG1842	Phage shock protein A
OE105_01510	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OE105_01515	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OE105_01520	COG4260	virion core protein, lumpy skin disease virus
OE105_01525	COG1794	racemase activity, acting on amino acids and derivatives
OE105_01530	COG0577	efflux transmembrane transporter activity
OE105_01530	COG1136	(ABC) transporter
OE105_01535	COG0577	efflux transmembrane transporter activity
OE105_01535	COG1136	(ABC) transporter
OE105_01540	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OE105_01545	COG5002	protein histidine kinase activity
OE105_01545	COG3850	Histidine kinase
OE105_01550	COG0745	RESPONSE REGULATOR receiver
OE105_01575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OE105_01585	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OE105_01595	COG1309	transcriptional regulator
OE105_01615	COG0549	Belongs to the carbamate kinase family
OE105_01660	COG1131	(ABC) transporter
OE105_01670	COG2814	Major facilitator Superfamily
OE105_01675	COG1595	DNA-templated transcription, initiation
OE105_01700	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OE105_01705	COG2270	Major facilitator Superfamily
OE105_01710	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OE105_01725	COG1028	Short-chain dehydrogenase reductase Sdr
OE105_01730	COG3880	PFAM UvrB UvrC protein
OE105_01735	COG3869	Catalyzes the specific phosphorylation of arginine residues in
OE105_01740	COG2211	Major facilitator Superfamily
OE105_01745	COG0076	glutamate decarboxylase activity
OE105_01755	COG3328	transposase activity
OE105_01805	COG1063	alcohol dehydrogenase
OE105_01815	COG1510	regulation of RNA biosynthetic process
OE105_01820	COG1125	glycine betaine transport
OE105_01820	COG0517	IMP dehydrogenase activity
OE105_01825	COG1174	glycine betaine transport
OE105_01835	COG1174	glycine betaine transport
OE105_01860	COG0840	transmembrane signaling receptor activity
OE105_01860	COG5278	phosphoserine phosphatase activity
OE105_01875	COG1271	oxidase subunit
OE105_01880	COG1294	oxidase, subunit
OE105_01885	COG4988	ABC transporter
OE105_01890	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OE105_01900	COG1012	belongs to the aldehyde dehydrogenase family
OE105_01915	COG1757	Na H antiporter
OE105_01925	COG1115	amino acid carrier protein
OE105_01930	COG1253	flavin adenine dinucleotide binding
OE105_01955	COG1988	membrane-bound metal-dependent
OE105_01975	COG4129	membrane
OE105_01985	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OE105_01990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OE105_01995	COG2096	Adenosyltransferase
OE105_02000	COG0735	belongs to the Fur family
OE105_02115	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OE105_02120	COG4605	iron ion homeostasis
OE105_02125	COG4604	ABC transporter, ATP-binding protein
OE105_02130	COG4607	ABC-type enterochelin transport system periplasmic component
OE105_02135	COG2329	Antibiotic biosynthesis monooxygenase
OE105_02140	COG2706	6-phosphogluconolactonase activity
OE105_02145	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OE105_02150	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OE105_02180	COG3629	intracellular signal transduction
OE105_02195	COG0411	ABC transporter
OE105_02225	COG1028	Short-chain dehydrogenase reductase Sdr
OE105_02230	COG0318	PFAM AMP-dependent synthetase and ligase
OE105_02235	COG0656	L-ascorbic acid biosynthetic process
OE105_02240	COG0564	pseudouridine synthase activity
OE105_02245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OE105_02250	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
OE105_02265	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OE105_02270	COG0583	DNA-binding transcription factor activity
OE105_02275	COG0067	glutamate synthase
OE105_02275	COG0069	glutamate synthase activity
OE105_02275	COG0070	glutamate synthase
OE105_02280	COG0493	'glutamate synthase
OE105_02285	COG1028	Short-chain dehydrogenase reductase Sdr
OE105_02290	COG2719	SpoVR family
OE105_02300	COG0745	RESPONSE REGULATOR receiver
OE105_02305	COG2205	protein histidine kinase activity
OE105_02315	COG0701	Predicted permease
OE105_02325	COG2197	response regulator
OE105_02330	COG1131	(ABC) transporter
OE105_02345	COG2963	transposase activity
OE105_02350	COG2801	Transposase and inactivated derivatives
OE105_02360	COG2814	Major facilitator Superfamily
OE105_02365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OE105_02370	COG3852	Histidine kinase
OE105_02375	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OE105_02385	COG3842	ATPase activity
OE105_02390	COG2508	Transcriptional regulator
OE105_02395	COG1937	Protein conserved in bacteria
OE105_02400	COG0189	ligase activity
OE105_02405	COG4399	Belongs to the UPF0754 family
OE105_02410	COG3679	Belongs to the UPF0342 family
OE105_02415	COG0561	phosphatase activity
OE105_02425	COG1252	NADH dehydrogenase
OE105_02435	COG4152	abc transporter atp-binding protein
OE105_02440	COG1668	transmembrane transport
OE105_02445	COG0420	3'-5' exonuclease activity
OE105_02450	COG4717	serine-type aminopeptidase activity
OE105_02455	COG3481	metal-dependent phosphohydrolase, HD sub domain
OE105_02465	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OE105_02485	COG1846	Transcriptional regulator
OE105_02495	COG0537	adenosine 5'-monophosphoramidase activity
OE105_02500	COG1131	(ABC) transporter
OE105_02505	COG4473	ABC transporter
OE105_02510	COG1473	amidohydrolase
OE105_02520	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OE105_02525	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OE105_02535	COG1234	tRNA 3'-trailer cleavage
OE105_02540	COG0095	Lipoate-protein ligase
OE105_02550	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OE105_02560	COG0501	Belongs to the peptidase M48B family
OE105_02570	COG4903	ComK protein
OE105_02580	COG0823	Involved in the tonB-independent uptake of proteins
OE105_02580	COG4946	Tricorn protease homolog
OE105_02580	COG1506	peptidase
OE105_02585	COG0398	Pfam SNARE associated Golgi protein
OE105_02590	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
OE105_02630	COG2311	Membrane
OE105_02640	COG3300	MHYT domain
OE105_02640	COG5001	Diguanylate cyclase
OE105_02645	COG0840	transmembrane signaling receptor activity
OE105_02645	COG5278	phosphoserine phosphatase activity
OE105_02655	COG2182	Extracellular solute-binding protein
OE105_02660	COG1175	transmembrane transport
OE105_02665	COG3833	ABC-type maltose transport systems, permease component
OE105_02670	COG1874	Beta-galactosidase
OE105_02670	COG0366	Alpha amylase catalytic
OE105_02675	COG1554	hydrolase, family 65, central catalytic
OE105_02690	COG1307	EDD domain protein, DegV family
OE105_02695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OE105_02700	COG0561	phosphatase activity
OE105_02705	COG1073	alpha beta
OE105_02710	COG2151	metal-sulfur cluster biosynthetic enzyme
OE105_02720	COG2267	carboxylic ester hydrolase activity
OE105_02735	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OE105_02740	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OE105_02745	COG5504	Zn-dependent protease
OE105_02755	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OE105_02760	COG0180	Tryptophanyl-tRNA synthetase
OE105_02770	COG1393	Belongs to the ArsC family
OE105_02780	COG4469	Competence protein
OE105_02785	COG1164	Oligoendopeptidase f
OE105_02795	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OE105_02800	COG0741	lytic transglycosylase activity
OE105_02805	COG4116	CYTH
OE105_02810	COG2357	RelA SpoT domain protein
OE105_02815	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OE105_02820	COG0564	pseudouridine synthase activity
OE105_02825	COG0569	domain protein
OE105_02825	COG0475	glutathione-regulated potassium exporter activity
OE105_02860	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OE105_02885	COG2323	membrane
OE105_02890	COG2153	protein acetylation
OE105_02895	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OE105_02910	COG2996	Protein conserved in bacteria
OE105_02920	COG1840	ABC-type Fe3 transport system, periplasmic component
OE105_02925	COG3842	ATPase activity
OE105_02930	COG1178	ABC-type Fe3 transport system permease component
OE105_02940	COG4753	response regulator
OE105_02940	COG2207	Transcriptional regulator
OE105_02945	COG2188	Transcriptional regulator
OE105_02950	COG2222	sugar isomerase
OE105_02960	COG1105	Belongs to the carbohydrate kinase PfkB family
OE105_02965	COG1114	Component of the transport system for branched-chain amino acids
OE105_02970	COG3180	Ammonia monooxygenase
OE105_02990	COG4841	protein insertion into membrane
OE105_03000	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OE105_03030	COG0328	RNA-DNA hybrid ribonuclease activity
OE105_03030	COG3341	Caulimovirus viroplasmin
OE105_03035	COG1715	Restriction endonuclease
OE105_03040	COG1331	Highly conserved protein containing a thioredoxin domain
OE105_03045	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
OE105_03045	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
OE105_03050	COG2313	pseudouridylate synthase activity
OE105_03065	COG1131	(ABC) transporter
OE105_03070	COG2197	response regulator
OE105_03075	COG4585	Histidine kinase
OE105_03085	COG0446	pyridine nucleotide-disulphide oxidoreductase
OE105_03090	COG1489	DNA binding
OE105_03105	COG1215	transferase activity, transferring glycosyl groups
OE105_03140	COG1131	(ABC) transporter
OE105_03155	COG1063	alcohol dehydrogenase
OE105_03180	COG4821	SIS domain
OE105_03200	COG3711	transcriptional antiterminator
OE105_03220	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OE105_03235	COG3314	Sporulation integral membrane protein YlbJ
OE105_03240	COG1228	amidohydrolase
OE105_03245	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OE105_03250	COG0010	Belongs to the arginase family
OE105_03255	COG0583	DNA-binding transcription factor activity
OE105_03260	COG2340	Cysteine-rich secretory protein family
OE105_03270	COG2226	methyltransferase
OE105_03275	COG1247	-acetyltransferase
OE105_03280	COG1609	Transcriptional regulator
OE105_03285	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
OE105_03295	COG1175	transmembrane transport
OE105_03300	COG0395	ABC-type sugar transport system, permease component
OE105_03305	COG0366	Alpha amylase catalytic
OE105_03350	COG0656	L-ascorbic acid biosynthetic process
OE105_03355	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OE105_03360	COG0095	Lipoate-protein ligase
OE105_03375	COG2076	Multidrug Resistance protein
OE105_03380	COG2076	Multidrug Resistance protein
OE105_03385	COG0426	domain, Protein
OE105_03385	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OE105_03395	COG1966	Carbon starvation protein
OE105_03405	COG0003	Pfam Anion-transporting ATPase
OE105_03410	COG2814	Major facilitator Superfamily
OE105_03415	COG0655	NAD(P)H dehydrogenase (quinone) activity
OE105_03420	COG1396	sequence-specific DNA binding
OE105_03460	COG0579	oxidoreductase
OE105_03465	COG0038	chloride channel
OE105_03470	COG1121	(ABC) transporter
OE105_03485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OE105_03490	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OE105_03495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OE105_03505	COG0861	Integral membrane protein TerC family
OE105_03515	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OE105_03520	COG1032	radical SAM domain protein
OE105_03525	COG5002	protein histidine kinase activity
OE105_03530	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OE105_03540	COG0542	response to heat
OE105_03545	COG3949	Membrane
OE105_03555	COG4873	Protein conserved in bacteria
OE105_03565	COG3773	Cell wall hydrolase
OE105_03570	COG1028	Short-chain dehydrogenase reductase Sdr
OE105_03580	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OE105_03585	COG1028	Short-chain dehydrogenase reductase Sdr
OE105_03590	COG2084	Dehydrogenase
OE105_03605	COG0436	Aminotransferase
OE105_03610	COG0835	chemotaxis
OE105_03620	COG1408	metallophosphoesterase
OE105_03630	COG4703	Protein of unknown function (DUF1797)
OE105_03635	COG0517	IMP dehydrogenase activity
OE105_03640	COG0583	DNA-binding transcription factor activity
OE105_03650	COG1473	amidohydrolase
OE105_03655	COG1132	(ABC) transporter
OE105_03660	COG1132	(ABC) transporter
OE105_03665	COG0569	domain protein
OE105_03670	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OE105_03680	COG0561	phosphatase activity
OE105_03700	COG0022	dehydrogenase e1 component
OE105_03725	COG4476	Belongs to the UPF0223 family
OE105_03730	COG4493	Belongs to the UPF0637 family
OE105_03735	COG0483	inositol monophosphate 1-phosphatase activity
OE105_03745	COG1217	gtp-binding protein TYPA
OE105_03755	COG4896	Protein conserved in bacteria
OE105_03765	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OE105_03770	COG2066	Belongs to the glutaminase family
OE105_03775	COG4838	Belongs to the UPF0358 family
OE105_03780	COG0772	Belongs to the SEDS family
OE105_03785	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
OE105_03790	COG3599	regulation of cell shape
OE105_03800	COG0116	Belongs to the methyltransferase superfamily
OE105_03810	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OE105_03820	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
OE105_03830	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OE105_03835	COG2233	PERMEase
OE105_03860	COG1278	Cold shock
OE105_03865	COG1321	iron dependent repressor
OE105_03885	COG0488	(ABC) transporter
OE105_03890	COG1413	lyase activity
OE105_03915	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OE105_03920	COG2135	peptidase activity
OE105_03930	COG1999	signal sequence binding
OE105_03935	COG2755	lipolytic protein G-D-S-L family
OE105_03945	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
OE105_03945	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OE105_03950	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OE105_03955	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OE105_03960	COG4479	Belongs to the UPF0346 family
OE105_03975	COG1876	peptidase activity
OE105_03980	COG0793	Belongs to the peptidase S41A family
OE105_03980	COG3409	Peptidoglycan-binding domain 1 protein
OE105_03990	COG1028	Short-chain dehydrogenase reductase Sdr
OE105_03995	COG0534	Mate efflux family protein
OE105_04005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OE105_04015	COG1793	dna ligase
OE105_04015	COG3285	dna ligase
OE105_04020	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OE105_04025	COG1404	Belongs to the peptidase S8 family
OE105_04025	COG4412	M6 family metalloprotease domain protein
OE105_04035	COG1278	Cold shock
OE105_04040	COG0567	Dehydrogenase, E1 component
OE105_04045	COG0508	dehydrogenase complex catalyzes the overall conversion of
OE105_04050	COG2151	metal-sulfur cluster biosynthetic enzyme
OE105_04060	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OE105_04065	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OE105_04070	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OE105_04075	COG1268	BioY protein
OE105_04095	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OE105_04100	COG0726	polysaccharide deacetylase
OE105_04105	COG0745	RESPONSE REGULATOR receiver
OE105_04115	COG5002	protein histidine kinase activity
OE105_04125	COG0501	Belongs to the peptidase M48B family
OE105_04135	COG0534	Mate efflux family protein
OE105_04145	COG1854	S-ribosylhomocysteine lyase activity
OE105_04160	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OE105_04170	COG1408	metallophosphoesterase
OE105_04175	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OE105_04180	COG1132	(ABC) transporter
OE105_04185	COG1132	(ABC) transporter
OE105_04190	COG0604	alcohol dehydrogenase
OE105_04195	COG1132	(ABC) transporter
OE105_04200	COG1132	(ABC) transporter
OE105_04210	COG1215	transferase activity, transferring glycosyl groups
OE105_04215	COG0494	nUDIX hydrolase
OE105_04225	COG1067	ATP-dependent peptidase activity
OE105_04230	COG0708	Exodeoxyribonuclease III
OE105_04245	COG1307	EDD domain protein, DegV family
OE105_04270	COG1028	Short-chain dehydrogenase reductase Sdr
OE105_04275	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OE105_04280	COG4989	oxidoreductase activity
OE105_04310	COG1131	(ABC) transporter
OE105_04320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OE105_04325	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OE105_04340	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OE105_04355	COG1061	Type III restriction enzyme res subunit
OE105_04420	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
OE105_04430	COG2195	Cleaves the N-terminal amino acid of tripeptides
OE105_04470	COG5564	TIM-barrel signal transduction protein
OE105_04480	COG5564	TIM-barrel signal transduction protein
OE105_04485	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OE105_04490	COG1309	transcriptional regulator
OE105_04515	COG3328	transposase activity
OE105_04525	COG0385	Bile acid
OE105_04535	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OE105_04555	COG4974	Belongs to the 'phage' integrase family
OE105_04640	COG0789	Transcriptional regulator
OE105_04645	COG1132	(ABC) transporter
OE105_04660	COG3829	transcription factor binding
OE105_04660	COG3290	protein histidine kinase activity
OE105_04665	COG2376	Dihydroxyacetone kinase
OE105_04670	COG1461	Dihydroxyacetone kinase
OE105_04680	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
OE105_04685	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OE105_04695	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OE105_04700	COG0463	Glycosyl transferase, family 2
OE105_04705	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OE105_04715	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OE105_04720	COG0583	DNA-binding transcription factor activity
OE105_04745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OE105_04780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OE105_04785	COG0640	Transcriptional regulator
OE105_04790	COG0798	PFAM Bile acid sodium symporter
OE105_04795	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OE105_04800	COG1368	sulfuric ester hydrolase activity
OE105_04810	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OE105_04815	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OE105_04820	COG1447	Phosphotransferase system cellobiose-specific component IIA
OE105_04825	COG2723	6-phospho-beta-galactosidase activity
OE105_04830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OE105_04830	COG3711	transcriptional antiterminator
OE105_04835	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OE105_04845	COG0420	3'-5' exonuclease activity
OE105_04850	COG4717	serine-type aminopeptidase activity
OE105_04855	COG1090	epimerase
OE105_04860	COG0471	metal ion transport
OE105_04860	COG0490	domain, Protein
OE105_04865	COG0318	PFAM AMP-dependent synthetase and ligase
OE105_04885	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
OE105_04890	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
OE105_04900	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OE105_04905	COG0187	DNA topoisomerase II activity
OE105_04910	COG1832	CoA-binding protein
OE105_04925	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OE105_04930	COG0860	N-Acetylmuramoyl-L-alanine amidase
OE105_04960	COG0824	Thioesterase
OE105_04975	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OE105_05000	COG4948	Mandelate Racemase Muconate Lactonizing
OE105_05010	COG0561	phosphatase activity
OE105_05035	COG2358	TRAP transporter, solute receptor (TAXI family
OE105_05040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OE105_05050	COG1012	belongs to the aldehyde dehydrogenase family
OE105_05055	COG0028	Belongs to the TPP enzyme family
OE105_05060	COG0436	Aminotransferase
OE105_05065	COG1757	Na H antiporter
OE105_05070	COG1960	acyl-CoA dehydrogenase activity
OE105_05075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OE105_05085	COG1301	dicarboxylic acid transport
OE105_05095	COG0519	Catalyzes the synthesis of GMP from XMP
OE105_05100	COG1607	acyl-coa hydrolase
OE105_05110	COG0668	transmembrane transport
OE105_05140	COG2201	protein-glutamate methylesterase activity
OE105_05145	COG0785	Cytochrome C biogenesis protein
OE105_05150	COG1132	(ABC) transporter
OE105_05155	COG1132	(ABC) transporter
OE105_05175	COG3763	UPF0154 protein
OE105_05195	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OE105_05205	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OE105_05215	COG0174	glutamine synthetase
OE105_05220	COG0789	Transcriptional regulator
OE105_05225	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
OE105_05230	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OE105_05240	COG0464	growth
OE105_05245	COG1923	regulation of RNA biosynthetic process
OE105_05250	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OE105_05255	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OE105_05260	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OE105_05265	COG0471	metal ion transport
OE105_05275	COG1408	metallophosphoesterase
OE105_05280	COG4550	Control of competence regulator ComK, YlbF/YmcA
OE105_05285	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OE105_05290	COG1013	pyruvate-flavodoxin oxidoreductase activity
OE105_05295	COG0674	pyruvate-flavodoxin oxidoreductase activity
OE105_05295	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
OE105_05300	COG2359	stage V sporulation protein S
OE105_05305	COG1692	metallophosphoesterase
OE105_05310	COG1418	mRNA catabolic process
OE105_05315	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OE105_05330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OE105_05340	COG1533	DNA photolyase activity
OE105_05345	COG0446	pyridine nucleotide-disulphide oxidoreductase
OE105_05375	COG1058	Belongs to the CinA family
OE105_05375	COG1546	Belongs to the CinA family
OE105_05380	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OE105_05385	COG1426	Protein conserved in bacteria
OE105_05400	COG0300	oxidoreductase activity
OE105_05405	COG0612	Peptidase, M16
OE105_05410	COG0612	Peptidase, M16
OE105_05415	COG1079	Belongs to the binding-protein-dependent transport system permease family
OE105_05420	COG4603	Belongs to the binding-protein-dependent transport system permease family
OE105_05425	COG3845	ABC transporter
OE105_05430	COG1744	ABC transporter substrate-binding protein PnrA-like
OE105_05435	COG4980	gas vesicle protein
OE105_05435	COG1674	ftsk spoiiie
OE105_05445	COG0740	serine-type endopeptidase activity
OE105_05450	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OE105_05455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OE105_05460	COG0527	aspartate kinase activity
OE105_05465	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OE105_05470	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OE105_05475	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OE105_05480	COG1873	PFAM PRC-barrel domain
OE105_05485	COG0612	Peptidase, M16
OE105_05490	COG0726	polysaccharide deacetylase
OE105_05495	COG1185	polyribonucleotide nucleotidyltransferase activity
OE105_05500	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OE105_05505	COG0196	riboflavin kinase activity
OE105_05510	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OE105_05515	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OE105_05520	COG1550	Protein conserved in bacteria
OE105_05525	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OE105_05530	COG1358	cellular component organization or biogenesis
OE105_05535	COG2740	Nucleic-acid-binding protein implicated in transcription termination
OE105_05540	COG0195	Participates in both transcription termination and antitermination
OE105_05550	COG2176	DNA-directed DNA polymerase activity
OE105_05555	COG0442	prolyl-tRNA aminoacylation
OE105_05560	COG0750	zinc metalloprotease
OE105_05570	COG4589	Belongs to the CDS family
OE105_05575	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OE105_05580	COG0233	cytoplasmic translational termination
OE105_05585	COG0528	UMP kinase activity
OE105_05590	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OE105_05595	COG0052	Belongs to the universal ribosomal protein uS2 family
OE105_05610	COG1191	sigma factor activity
OE105_05615	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
OE105_05620	COG1776	CheC inhibitor of MCP methylation
OE105_05625	COG0835	chemotaxis
OE105_05630	COG0643	Histidine kinase
OE105_05630	COG2198	Histidine kinase
OE105_05635	COG2201	protein-glutamate methylesterase activity
OE105_05640	COG0455	bacterial-type flagellum organization
OE105_05645	COG1419	protein localization to endoplasmic reticulum
OE105_05650	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OE105_05655	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OE105_05660	COG1684	flagellar biosynthetic protein fliR
OE105_05665	COG1987	bacterial-type flagellum assembly
OE105_05670	COG1338	Plays a role in the flagellum-specific transport system
OE105_05675	COG3190	flagellar
OE105_05680	COG2201	protein-glutamate methylesterase activity
OE105_05685	COG1776	CheC inhibitor of MCP methylation
OE105_05685	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OE105_05690	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OE105_05695	COG1580	Controls the rotational direction of flagella during chemotaxis
OE105_05700	COG1582	Flagellar protein (FlbD)
OE105_05715	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
OE105_05730	COG2882	bacterial-type flagellum organization
OE105_05735	COG1157	protein secretion by the type III secretion system
OE105_05745	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OE105_05750	COG1766	The M ring may be actively involved in energy transduction
OE105_05755	COG1677	Flagellar hook-basal body complex protein FliE
OE105_05760	COG1558	bacterial-type flagellum-dependent cell motility
OE105_05765	COG1815	bacterial-type flagellum-dependent cell motility
OE105_05770	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OE105_05775	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OE105_05780	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OE105_05785	COG4974	Belongs to the 'phage' integrase family
OE105_05790	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OE105_05795	COG0758	DNA mediated transformation
OE105_05800	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OE105_05805	COG0045	succinate-CoA ligase (ADP-forming) activity
OE105_05810	COG2257	FlhB HrpN YscU SpaS Family
OE105_05820	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OE105_05825	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OE105_05835	COG0335	large ribosomal subunit rRNA binding
OE105_05840	COG0336	Belongs to the RNA methyltransferase TrmD family
OE105_05845	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OE105_05855	COG1837	Belongs to the UPF0109 family
OE105_05860	COG0228	four-way junction DNA binding
OE105_05865	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OE105_05870	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
OE105_05890	COG0714	Associated with various cellular activities
OE105_05905	COG1131	(ABC) transporter
OE105_05915	COG0552	protein localization to endoplasmic reticulum
OE105_05920	COG1196	nuclear chromosome segregation
OE105_05925	COG0571	ribonuclease III activity
OE105_05930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OE105_05935	COG1028	Short-chain dehydrogenase reductase Sdr
OE105_05940	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OE105_05945	COG0416	fatty acid biosynthetic process
OE105_05950	COG1349	DNA-binding transcription factor activity
OE105_05955	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OE105_05960	COG1760	l-serine dehydratase
OE105_05965	COG1760	l-serine dehydratase
OE105_05970	COG1461	Dihydroxyacetone kinase
OE105_05975	COG1302	Protein conserved in bacteria
OE105_05980	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OE105_05990	COG1564	THIamine pyrophosphokinase
OE105_05995	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OE105_06000	COG1162	GTPase activity
OE105_06005	COG0515	serine threonine protein kinase
OE105_06005	COG2815	serine threonine protein kinase
OE105_06010	COG0631	protein serine/threonine phosphatase activity
OE105_06015	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OE105_06015	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OE105_06020	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OE105_06025	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OE105_06030	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OE105_06040	COG0194	GDP metabolic process
OE105_06045	COG2052	Domain of unknown function (DUF370)
OE105_06050	COG1561	YicC-like family, N-terminal region
OE105_06055	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OE105_06060	COG1293	RNA-binding protein homologous to eukaryotic snRNP
OE105_06065	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OE105_06070	COG0564	pseudouridine synthase activity
OE105_06075	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OE105_06080	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OE105_06085	COG3599	regulation of cell shape
OE105_06090	COG2302	S4 RNA-binding domain
OE105_06095	COG0762	integral membrane protein
OE105_06100	COG1799	cell septum assembly
OE105_06105	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OE105_06110	COG1496	oxidoreductase activity
OE105_06115	COG1191	sigma factor activity
OE105_06120	COG1191	sigma factor activity
OE105_06130	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OE105_06135	COG0849	cell division
OE105_06140	COG3856	small basic protein
OE105_06145	COG3879	Bacterial protein of unknown function (DUF881)
OE105_06150	COG3879	Bacterial protein of unknown function (DUF881)
OE105_06155	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OE105_06160	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OE105_06165	COG0772	Belongs to the SEDS family
OE105_06170	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OE105_06175	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OE105_06185	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OE105_06190	COG0768	penicillin binding
OE105_06195	COG0768	penicillin binding
OE105_06205	COG0275	rRNA processing
OE105_06215	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
OE105_06225	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OE105_06230	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OE105_06235	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
OE105_06240	COG0454	-acetyltransferase
OE105_06250	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OE105_06255	COG1399	metal-binding, possibly nucleic acid-binding protein
OE105_06260	COG1323	Belongs to the UPF0348 family
OE105_06265	COG3480	Lon protease (S16) C-terminal proteolytic domain
OE105_06270	COG1752	Esterase of the alpha-beta hydrolase superfamily
OE105_06275	COG3314	Sporulation integral membrane protein YlbJ
OE105_06280	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OE105_06285	COG0742	ribosomal rna small subunit methyltransferase
OE105_06295	COG4471	UPF0298 protein
OE105_06300	COG3679	Belongs to the UPF0342 family
OE105_06315	COG2340	Cysteine-rich secretory protein family
OE105_06320	COG2340	Cysteine-rich secretory protein family
OE105_06325	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
OE105_06340	COG3336	cytochrome c oxidase
OE105_06350	COG1845	cytochrome c oxidase, subunit III
OE105_06355	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OE105_06365	COG0109	protoheme IX farnesyltransferase activity
OE105_06380	COG3359	exonuclease
OE105_06385	COG1111	helicase
OE105_06385	COG1205	dead DEAH box helicase
OE105_06410	COG3331	DNA recombination
OE105_06415	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OE105_06415	COG4499	WXG100 protein secretion system (Wss), protein YukC
OE105_06425	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OE105_06430	COG3935	DnaD domain protein
OE105_06435	COG0017	Asparaginyl-tRNA synthetase
OE105_06440	COG0436	Aminotransferase
OE105_06455	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OE105_06460	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OE105_06480	COG0438	transferase activity, transferring glycosyl groups
OE105_06485	COG1803	Methylglyoxal synthase
OE105_06490	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OE105_06495	COG1694	Mazg nucleotide pyrophosphohydrolase
OE105_06500	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OE105_06505	COG2738	Putative neutral zinc metallopeptidase
OE105_06515	COG4347	Protein of unknown function (DUF1405)
OE105_06525	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OE105_06545	COG0457	Tetratricopeptide repeat
OE105_06555	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OE105_06560	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OE105_06565	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OE105_06570	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OE105_06575	COG0105	UTP biosynthetic process
OE105_06580	COG0142	geranyltranstransferase activity
OE105_06585	COG2226	methyltransferase
OE105_06590	COG0142	geranyltranstransferase activity
OE105_06600	COG0302	gtp cyclohydrolase
OE105_06605	COG0776	regulation of translation
OE105_06610	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OE105_06625	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OE105_06630	COG1160	GTP binding
OE105_06650	COG0539	negative regulation of cytoplasmic translation
OE105_06660	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OE105_06675	COG2959	enzyme of heme biosynthesis
OE105_06680	COG3409	Peptidoglycan-binding domain 1 protein
OE105_06680	COG3773	Cell wall hydrolase
OE105_06685	COG2339	peptidase activity
OE105_06690	COG3842	ATPase activity
OE105_06695	COG3833	ABC-type maltose transport systems, permease component
OE105_06700	COG1175	transmembrane transport
OE105_06710	COG0252	asparaginase activity
OE105_06715	COG0492	ferredoxin-NADP+ reductase activity
OE105_06720	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OE105_06740	COG1266	CAAX protease self-immunity
OE105_06745	COG0514	ATP-dependent DNA helicase (RecQ)
OE105_06755	COG1141	Ferredoxin
OE105_06760	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OE105_06775	COG1595	DNA-templated transcription, initiation
OE105_06780	COG5002	protein histidine kinase activity
OE105_06785	COG0745	RESPONSE REGULATOR receiver
OE105_06790	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OE105_06795	COG1333	cytochrome c biogenesis protein
OE105_06800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OE105_06805	COG1187	pseudouridine synthase activity
OE105_06810	COG0700	Nucleoside recognition
OE105_06815	COG2715	membrane protein required for spore maturation
OE105_06820	COG1686	Belongs to the peptidase S11 family
OE105_06830	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OE105_06840	COG1547	Domain of unknown function (DUF309)
OE105_06850	COG0019	diaminopimelate decarboxylase activity
OE105_06855	COG0697	spore germination
OE105_06885	COG1686	Belongs to the peptidase S11 family
OE105_06900	COG4974	Belongs to the 'phage' integrase family
OE105_06910	COG0735	belongs to the Fur family
OE105_06915	COG1300	Membrane
OE105_06920	COG1379	DNA repair
OE105_06925	COG0494	nUDIX hydrolase
OE105_06935	COG0667	Aldo Keto reductase
OE105_06950	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OE105_06970	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OE105_06975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OE105_06990	COG0300	oxidoreductase activity
OE105_06995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OE105_07000	COG1902	pentaerythritol trinitrate reductase activity
OE105_07005	COG1234	tRNA 3'-trailer cleavage
OE105_07010	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OE105_07015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OE105_07020	COG0835	chemotaxis
OE105_07025	COG2195	Cleaves the N-terminal amino acid of tripeptides
OE105_07030	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OE105_07035	COG0346	lactoylglutathione lyase activity
OE105_07045	COG1376	ErfK ybiS ycfS ynhG family protein
OE105_07050	COG1703	isobutyryl-CoA mutase activity
OE105_07060	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OE105_07065	COG0508	dehydrogenase complex catalyzes the overall conversion of
OE105_07070	COG0022	dehydrogenase e1 component
OE105_07075	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OE105_07080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OE105_07090	COG3290	protein histidine kinase activity
OE105_07090	COG3829	transcription factor binding
OE105_07100	COG0584	glycerophosphoryl diester phosphodiesterase
OE105_07115	COG0750	zinc metalloprotease
OE105_07120	COG0497	DNA recombination
OE105_07130	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
OE105_07135	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OE105_07145	COG0142	geranyltranstransferase activity
OE105_07150	COG1722	exodeoxyribonuclease VII activity
OE105_07155	COG1570	exodeoxyribonuclease VII activity
OE105_07160	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OE105_07165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OE105_07170	COG1302	Protein conserved in bacteria
OE105_07175	COG0439	Biotin carboxylase
OE105_07180	COG0511	ligase activity, forming carbon-carbon bonds
OE105_07220	COG3854	ATPases associated with a variety of cellular activities
OE105_07225	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OE105_07230	COG0006	proline dipeptidase activity
OE105_07255	COG1752	Esterase of the alpha-beta hydrolase superfamily
OE105_07260	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OE105_07265	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OE105_07270	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OE105_07275	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OE105_07280	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OE105_07285	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OE105_07320	COG4537	Required for transformation and DNA binding
OE105_07325	COG1459	type II secretion system
OE105_07330	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OE105_07350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OE105_07380	COG1368	sulfuric ester hydrolase activity
OE105_07385	COG1940	carbohydrate kinase activity
OE105_07390	COG4483	Protein conserved in bacteria
OE105_07400	COG0457	Tetratricopeptide repeat
OE105_07400	COG0705	Rhomboid family
OE105_07405	COG1836	PFAM Integral membrane protein DUF92
OE105_07410	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OE105_07415	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OE105_07435	COG0768	penicillin binding
OE105_07440	COG0477	Major facilitator Superfamily
OE105_07460	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OE105_07465	COG4709	membrane
OE105_07470	COG0735	belongs to the Fur family
OE105_07475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OE105_07480	COG1121	(ABC) transporter
OE105_07490	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
OE105_07495	COG0513	Belongs to the DEAD box helicase family
OE105_07505	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OE105_07510	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OE105_07515	COG2384	SAM-dependent methyltransferase
OE105_07520	COG2010	Cytochrome c
OE105_07525	COG1960	acyl-CoA dehydrogenase activity
OE105_07530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OE105_07535	COG0358	DNA primase activity
OE105_07540	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
OE105_07545	COG0517	IMP dehydrogenase activity
OE105_07550	COG0751	glycine-tRNA ligase activity
OE105_07555	COG0752	glycyl-tRNA synthetase alpha subunit
OE105_07560	COG1381	Involved in DNA repair and RecF pathway recombination
OE105_07575	COG0295	cytidine deaminase activity
OE105_07580	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OE105_07585	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OE105_07590	COG1480	7TM receptor with intracellular HD hydrolase
OE105_07595	COG1702	phosphate starvation-inducible protein PhoH
OE105_07615	COG4864	UPF0365 protein
OE105_07620	COG1030	water channel activity
OE105_07625	COG1610	YqeY-like protein
OE105_07630	COG0828	Belongs to the bacterial ribosomal protein bS21 family
OE105_07635	COG1283	sodium-dependent phosphate transmembrane transporter activity
OE105_07645	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OE105_07650	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OE105_07655	COG2264	protein methyltransferase activity
OE105_07660	COG0484	heat shock protein binding
OE105_07665	COG0443	Heat shock 70 kDa protein
OE105_07670	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OE105_07675	COG1420	regulation of RNA biosynthetic process
OE105_07680	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OE105_07685	COG0481	GTPase activity
OE105_07695	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
OE105_07700	COG0268	Binds directly to 16S ribosomal RNA
OE105_07705	COG1466	dna polymerase III delta subunit
OE105_07715	COG2333	competence protein COMEC
OE105_07715	COG0658	competence protein
OE105_07720	COG2131	deaminase
OE105_07725	COG1596	polysaccharide export
OE105_07725	COG1555	photosystem II stabilization
OE105_07730	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OE105_07735	COG2226	methyltransferase
OE105_07740	COG0799	negative regulation of ribosome biogenesis
OE105_07745	COG1713	HD superfamily hydrolase involved in NAD metabolism
OE105_07750	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OE105_07755	COG1534	Rna-binding protein
OE105_07765	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OE105_07770	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
OE105_07805	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OE105_07815	COG0768	penicillin binding
OE105_07820	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OE105_07825	COG0572	uridine kinase
OE105_07830	COG0826	peptidase U32
OE105_07835	COG0826	peptidase U32
OE105_07840	COG4122	O-methyltransferase activity
OE105_07845	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OE105_07850	COG3906	Belongs to the UPF0473 family
OE105_07855	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OE105_07860	COG4472	Bacterial protein of unknown function (DUF965)
OE105_07865	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OE105_07870	COG0628	permease
OE105_07880	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OE105_07885	COG0482	sulfurtransferase activity
OE105_07890	COG1104	cysteine desulfurase activity
OE105_07895	COG1959	2 iron, 2 sulfur cluster binding
OE105_07900	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OE105_07905	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OE105_07915	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OE105_07920	COG0124	histidyl-tRNA synthetase
OE105_07930	COG1490	D-aminoacyl-tRNA deacylase activity
OE105_07935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OE105_07940	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OE105_07945	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OE105_07945	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
OE105_07950	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OE105_07950	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OE105_07965	COG2244	polysaccharide biosynthetic process
OE105_07975	COG1862	Preprotein translocase
OE105_07980	COG0343	queuine tRNA-ribosyltransferase activity
OE105_07985	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OE105_07995	COG2255	four-way junction helicase activity
OE105_08015	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OE105_08020	COG1388	LysM domain
OE105_08025	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OE105_08035	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OE105_08040	COG2868	ribosomal protein
OE105_08045	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OE105_08050	COG1994	Peptidase M50
OE105_08060	COG2894	cell division
OE105_08065	COG0850	regulation of cytokinetic process
OE105_08075	COG1792	Involved in formation and maintenance of cell shape
OE105_08080	COG1077	Cell shape determining protein MreB Mrl
OE105_08085	COG2003	Belongs to the UPF0758 family
OE105_08100	COG3706	GGDEF domain
OE105_08105	COG0285	dihydrofolate synthase activity
OE105_08110	COG0525	valine-tRNA ligase activity
OE105_08125	COG1388	LysM domain
OE105_08130	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OE105_08135	COG0113	porphobilinogen synthase activity
OE105_08140	COG1587	Uroporphyrinogen-III synthase
OE105_08145	COG0181	hydroxymethylbilane synthase activity
OE105_08150	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OE105_08160	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OE105_08165	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OE105_08175	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OE105_08180	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OE105_08185	COG1067	ATP-dependent peptidase activity
OE105_08185	COG0470	DNA polymerase III
OE105_08190	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OE105_08195	COG0544	peptidyl-prolyl cis-trans isomerase activity
OE105_08220	COG0622	Phosphoesterase
OE105_08225	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OE105_08230	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OE105_08235	COG5401	PFAM Sporulation and spore germination
OE105_08245	COG1846	Transcriptional regulator
OE105_08250	COG2197	response regulator
OE105_08260	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OE105_08265	COG1053	succinate dehydrogenase
OE105_08270	COG2009	succinate dehydrogenase
OE105_08275	COG1719	4-vinyl reductase, 4VR
OE105_08285	COG0322	excinuclease ABC activity
OE105_08290	COG3118	belongs to the thioredoxin family
OE105_08295	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
OE105_08300	COG2086	electron transfer activity
OE105_08305	COG1024	Enoyl-CoA hydratase
OE105_08310	COG1309	transcriptional regulator
OE105_08315	COG0318	PFAM AMP-dependent synthetase and ligase
OE105_08320	COG3766	membrane
OE105_08325	COG1193	negative regulation of DNA recombination
OE105_08330	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OE105_08330	COG1796	DNA polymerase
OE105_08335	COG1286	toxin biosynthetic process
OE105_08340	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
OE105_08345	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OE105_08345	COG0072	phenylalanine-tRNA ligase activity
OE105_08350	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OE105_08355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OE105_08365	COG1363	Peptidase, m42
OE105_08370	COG1846	Transcriptional regulator
OE105_08380	COG1132	(ABC) transporter
OE105_08400	COG3326	Membrane
OE105_08405	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OE105_08420	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OE105_08430	COG1484	DNA-dependent DNA replication
OE105_08435	COG3611	Membrane attachment protein
OE105_08440	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OE105_08450	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OE105_08455	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OE105_08460	COG0237	dephospho-CoA kinase activity
OE105_08465	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OE105_08470	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OE105_08470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OE105_08475	COG0330	HflC and HflK could
OE105_08485	COG5002	protein histidine kinase activity
OE105_08490	COG0745	RESPONSE REGULATOR receiver
OE105_08500	COG0538	isocitrate dehydrogenase activity
OE105_08505	COG0372	Belongs to the citrate synthase family
OE105_08510	COG0628	permease
OE105_08515	COG3030	protein affecting phage T7 exclusion by the F plasmid
OE105_08525	COG0205	6-phosphofructokinase activity
OE105_08530	COG0825	malonyl-CoA metabolic process
OE105_08535	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OE105_08540	COG2186	Transcriptional regulator
OE105_08545	COG0281	malic enzyme
OE105_08550	COG0587	DNA-directed DNA polymerase activity
OE105_08565	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
OE105_08575	COG4109	DRTGG domain
OE105_08585	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
OE105_08590	COG0006	proline dipeptidase activity
OE105_08600	COG0589	response to stress
OE105_08615	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OE105_08620	COG0827	DNA restriction-modification system
OE105_08625	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
OE105_08630	COG3874	Sporulation protein YtfJ
OE105_08640	COG1714	RDD family
OE105_08645	COG0616	signal peptide processing
OE105_08650	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OE105_08655	COG2962	Rard protein
OE105_08680	COG0301	tRNA thio-modification
OE105_08685	COG1104	cysteine desulfurase activity
OE105_08690	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
OE105_08695	COG1956	GAF domain-containing protein
OE105_08700	COG2199	diguanylate cyclase activity
OE105_08700	COG2203	Gaf domain
OE105_08710	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OE105_08715	COG1309	transcriptional regulator
OE105_08720	COG0318	PFAM AMP-dependent synthetase and ligase
OE105_08730	COG3711	transcriptional antiterminator
OE105_08730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OE105_08735	COG2723	6-phospho-beta-galactosidase activity
OE105_08740	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OE105_08750	COG2723	6-phospho-beta-galactosidase activity
OE105_08755	COG1447	Phosphotransferase system cellobiose-specific component IIA
OE105_08765	COG2514	catechol 2,3-dioxygenase activity
OE105_08780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OE105_08800	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
OE105_08810	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
OE105_08825	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OE105_08830	COG1269	ATP hydrolysis coupled proton transport
OE105_08845	COG0697	spore germination
OE105_08865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OE105_08870	COG0454	-acetyltransferase
OE105_08875	COG0517	IMP dehydrogenase activity
OE105_08880	COG0123	including yeast histone deacetylase and acetoin utilization protein
OE105_08890	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OE105_08900	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
OE105_08900	COG1605	Chorismate mutase
OE105_08905	COG0849	cell division
OE105_08910	COG3118	belongs to the thioredoxin family
OE105_08930	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OE105_08935	COG4555	ABC transporter
OE105_08950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OE105_08955	COG4848	Belongs to the UPF0354 family
OE105_08970	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
OE105_08975	COG1363	Peptidase, m42
OE105_08985	COG2031	fatty acid transporter
OE105_08990	COG0697	spore germination
OE105_08995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OE105_09000	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OE105_09010	COG0510	thiamine kinase activity
OE105_09015	COG1597	lipid kinase activity
OE105_09025	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OE105_09035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OE105_09040	COG1349	DNA-binding transcription factor activity
OE105_09045	COG1187	pseudouridine synthase activity
OE105_09055	COG2244	polysaccharide biosynthetic process
OE105_09060	COG2081	HI0933 family
OE105_09070	COG0495	leucyl-tRNA aminoacylation
OE105_09080	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OE105_09085	COG2814	Major facilitator Superfamily
OE105_09090	COG1242	4 iron, 4 sulfur cluster binding
OE105_09095	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
OE105_09100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OE105_09110	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OE105_09115	COG4990	cell redox homeostasis
OE105_09120	COG0367	asparagine synthase
OE105_09125	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OE105_09130	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OE105_09140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OE105_09145	COG0601	transmembrane transport
OE105_09150	COG4608	Belongs to the ABC transporter superfamily
OE105_09165	COG1506	peptidase
OE105_09170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OE105_09175	COG1116	anion transmembrane transporter activity
OE105_09180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OE105_09185	COG0494	nUDIX hydrolase
OE105_09200	COG0783	Belongs to the Dps family
OE105_09205	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OE105_09215	COG0318	PFAM AMP-dependent synthetase and ligase
OE105_09220	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OE105_09225	COG0596	Alpha beta hydrolase
OE105_09235	COG1169	isochorismate synthase
OE105_09240	COG1575	Belongs to the MenA family. Type 1 subfamily
OE105_09390	COG1285	pathogenesis
OE105_09395	COG0860	N-Acetylmuramoyl-L-alanine amidase
OE105_09420	COG1131	(ABC) transporter
OE105_09425	COG0842	Transport permease protein
OE105_09430	COG4585	Histidine kinase
OE105_09435	COG2197	response regulator
OE105_09460	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OE105_09470	COG1979	alcohol dehydrogenase
OE105_09475	COG2155	Conserved Protein
OE105_09480	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OE105_09495	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
OE105_09510	COG2814	Major facilitator Superfamily
OE105_09515	COG2050	protein possibly involved in aromatic compounds catabolism
OE105_09520	COG1320	monovalent cation:proton antiporter activity
OE105_09525	COG2212	antiporter activity
OE105_09530	COG1863	multisubunit Na H antiporter MnhE subunit
OE105_09535	COG0651	ATP synthesis coupled electron transport
OE105_09540	COG1006	Multisubunit Na H antiporter MnhC subunit
OE105_09545	COG2111	Na H antiporter
OE105_09550	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OE105_09550	COG2111	Na H antiporter
OE105_09565	COG2986	histidine ammonia-lyase
OE105_09580	COG0681	Belongs to the peptidase S26 family
OE105_09595	COG0681	Belongs to the peptidase S26 family
OE105_09620	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OE105_09635	COG1024	Enoyl-CoA hydratase
OE105_09645	COG1250	3-hydroxyacyl-CoA dehydrogenase
OE105_09650	COG1024	Enoyl-CoA hydratase
OE105_09665	COG2151	metal-sulfur cluster biosynthetic enzyme
OE105_09680	COG3396	Phenylacetate-CoA oxygenase
OE105_09685	COG2252	PERMEase
OE105_09690	COG0039	L-malate dehydrogenase activity
OE105_09700	COG2814	Major facilitator Superfamily
OE105_09705	COG0366	Alpha amylase catalytic
OE105_09710	COG0366	Alpha amylase catalytic
OE105_09715	COG2718	Belongs to the UPF0229 family
OE105_09720	COG4608	Belongs to the ABC transporter superfamily
OE105_09725	COG0444	Belongs to the ABC transporter superfamily
OE105_09730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OE105_09735	COG0601	transmembrane transport
OE105_09740	COG4166	transmembrane transport
OE105_09760	COG2766	serine protein kinase
OE105_09810	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OE105_09820	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OE105_09825	COG0450	alkyl hydroperoxide reductase
OE105_09835	COG3584	3D domain protein
OE105_09850	COG1252	NADH dehydrogenase
OE105_09855	COG0492	ferredoxin-NADP+ reductase activity
OE105_09860	COG0316	Belongs to the HesB IscA family
OE105_09865	COG4844	belongs to the
OE105_09870	COG1252	NADH dehydrogenase
OE105_09875	COG4837	Protein of unknown function (DUF1462)
OE105_09880	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
OE105_09885	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OE105_09890	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OE105_09895	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OE105_09900	COG0647	UMP catabolic process
OE105_09905	COG2445	Protein of unknown function DUF86
OE105_09910	COG4470	Protein conserved in bacteria
OE105_09915	COG0739	heme binding
OE105_09925	COG0733	neurotransmitter:sodium symporter activity
OE105_09930	COG1757	Na H antiporter
OE105_09940	COG3377	Domain of unknown function (DUF1805)
OE105_09945	COG0737	Belongs to the 5'-nucleotidase family
OE105_09950	COG0719	Fe-S assembly protein
OE105_09955	COG0822	iron-sulfur transferase activity
OE105_09960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OE105_09965	COG0719	Fe-S assembly protein
OE105_09970	COG0396	ATPase activity
OE105_09975	COG1464	Belongs to the NlpA lipoprotein family
OE105_09980	COG2011	ABC-type metal ion transport system permease component
OE105_09985	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OE105_10000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OE105_10005	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OE105_10010	COG0509	glycine decarboxylation via glycine cleavage system
OE105_10015	COG1393	Belongs to the ArsC family
OE105_10020	COG1960	acyl-CoA dehydrogenase activity
OE105_10025	COG0183	Belongs to the thiolase family
OE105_10030	COG1024	Enoyl-CoA hydratase
OE105_10030	COG1250	3-hydroxyacyl-CoA dehydrogenase
OE105_10035	COG0506	proline dehydrogenase activity
OE105_10045	COG5577	PFAM Coat F domain
OE105_10050	COG0628	permease
OE105_10095	COG0765	amino acid transport
OE105_10100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OE105_10110	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OE105_10115	COG0557	exoribonuclease II activity
OE105_10120	COG1647	Serine aminopeptidase, S33
OE105_10125	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OE105_10145	COG0148	phosphopyruvate hydratase activity
OE105_10155	COG0149	triose-phosphate isomerase activity
OE105_10160	COG0126	phosphoglycerate kinase activity
OE105_10170	COG2390	Transcriptional regulator
OE105_10180	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
OE105_10195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OE105_10200	COG0740	serine-type endopeptidase activity
OE105_10205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OE105_10210	COG1481	regulation of sporulation
OE105_10215	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OE105_10225	COG1051	belongs to the nudix hydrolase family
OE105_10230	COG0492	ferredoxin-NADP+ reductase activity
OE105_10235	COG0457	Tetratricopeptide repeat
OE105_10240	COG0110	maltose O-acetyltransferase activity
OE105_10245	COG0546	phosphoglycolate phosphatase activity
OE105_10250	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
OE105_10260	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OE105_10265	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OE105_10270	COG0363	glucosamine-6-phosphate deaminase activity
OE105_10275	COG3595	metallopeptidase activity
OE105_10280	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OE105_10285	COG0556	nucleotide-excision repair
OE105_10290	COG2223	nitrite transmembrane transporter activity
OE105_10310	COG1105	Belongs to the carbohydrate kinase PfkB family
OE105_10315	COG1349	DNA-binding transcription factor activity
OE105_10340	COG1876	peptidase activity
OE105_10375	COG1337	RAMP superfamily
OE105_10395	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
OE105_10400	COG1518	maintenance of DNA repeat elements
OE105_10450	COG2217	Heavy metal translocating P-type atpase
OE105_10455	COG2608	mercury ion transmembrane transporter activity
OE105_10460	COG1937	Protein conserved in bacteria
OE105_10475	COG5522	Integral membrane protein (intg_mem_TP0381)
OE105_10480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OE105_10485	COG0793	Belongs to the peptidase S41A family
OE105_10485	COG3409	Peptidoglycan-binding domain 1 protein
OE105_10490	COG0217	transcriptional regulatory protein
OE105_10495	COG0737	Belongs to the 5'-nucleotidase family
OE105_10500	COG1131	(ABC) transporter
OE105_10505	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OE105_10510	COG0741	lytic transglycosylase activity
OE105_10510	COG1196	nuclear chromosome segregation
OE105_10510	COG0739	heme binding
OE105_10515	COG2177	Part of the ABC transporter FtsEX involved in
OE105_10520	COG2884	Cell division ATP-binding protein ftsE
OE105_10535	COG0653	protein targeting
OE105_10540	COG2059	Chromate
OE105_10545	COG2059	Chromate
OE105_10565	COG1516	flagellar protein fliS
OE105_10570	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OE105_10575	COG1334	flagellar protein FlaG
OE105_10580	COG2807	transmembrane transport
OE105_10610	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OE105_10615	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
OE105_10625	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OE105_10630	COG1256	bacterial-type flagellum assembly
OE105_10630	COG4786	Flagellar basal body rod
OE105_10640	COG2747	anti-sigma28 factor FlgM
OE105_10650	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OE105_10655	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
OE105_10660	COG1307	EDD domain protein, DegV family
OE105_10665	COG2197	response regulator
OE105_10670	COG4585	Histidine kinase
OE105_10680	COG2200	EAL domain
OE105_10680	COG2199	diguanylate cyclase activity
OE105_10685	COG1396	sequence-specific DNA binding
OE105_10690	COG1063	alcohol dehydrogenase
OE105_10695	COG1511	domain protein
OE105_10700	COG1309	transcriptional regulator
OE105_10705	COG1739	Uncharacterized protein family UPF0029
OE105_10710	COG1316	TRANSCRIPTIONal
OE105_10715	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OE105_10720	COG3764	Sortase (surface protein transpeptidase)
OE105_10730	COG2199	diguanylate cyclase activity
OE105_10730	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
OE105_10735	COG1316	TRANSCRIPTIONal
OE105_10740	COG1254	Belongs to the acylphosphatase family
OE105_10750	COG1609	Transcriptional regulator
OE105_10755	COG0395	ABC-type sugar transport system, permease component
OE105_10760	COG1175	transmembrane transport
OE105_10770	COG1554	hydrolase, family 65, central catalytic
OE105_10775	COG1309	transcriptional regulator
OE105_10785	COG2190	(PTS) system
OE105_10790	COG3711	transcriptional antiterminator
OE105_10795	COG1263	PTS System
OE105_10795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OE105_10800	COG1024	Enoyl-CoA hydratase
OE105_10810	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
OE105_10840	COG0460	homoserine dehydrogenase
OE105_10845	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OE105_10865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OE105_10870	COG1024	Enoyl-CoA hydratase
OE105_10880	COG0318	PFAM AMP-dependent synthetase and ligase
OE105_10890	COG0318	PFAM AMP-dependent synthetase and ligase
OE105_10895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OE105_10900	COG0183	Belongs to the thiolase family
OE105_10905	COG1960	acyl-CoA dehydrogenase activity
OE105_10915	COG1309	transcriptional regulator
OE105_10925	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OE105_10940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OE105_10955	COG3959	Transketolase, thiamine diphosphate binding domain
OE105_10960	COG3958	Transketolase
OE105_10980	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OE105_10985	COG0573	inorganic phosphate transmembrane transporter activity
OE105_10990	COG0581	inorganic phosphate transmembrane transporter activity
OE105_11000	COG0704	Plays a role in the regulation of phosphate uptake
OE105_11005	COG0737	Belongs to the 5'-nucleotidase family
OE105_11010	COG0383	alpha-mannosidase activity
OE105_11015	COG0383	alpha-mannosidase activity
OE105_11020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OE105_11020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OE105_11020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OE105_11025	COG1737	Transcriptional regulator
OE105_11030	COG1929	Belongs to the glycerate kinase type-1 family
OE105_11055	COG1523	belongs to the glycosyl hydrolase 13 family
OE105_11060	COG0737	Belongs to the 5'-nucleotidase family
OE105_11075	COG1361	Conserved repeat domain
OE105_11095	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OE105_11110	COG1216	Glycosyl transferase, family 2
OE105_11125	COG0438	transferase activity, transferring glycosyl groups
OE105_11145	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OE105_11150	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OE105_11155	COG4464	protein tyrosine phosphatase activity
OE105_11160	COG0489	protein tyrosine kinase activity
OE105_11165	COG3944	biosynthesis protein
OE105_11195	COG1134	teichoic acid transport
OE105_11200	COG1682	transport, permease protein
OE105_11205	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OE105_11210	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OE105_11215	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
OE105_11230	COG4193	domain, Protein
OE105_11235	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
OE105_11255	COG1368	sulfuric ester hydrolase activity
OE105_11260	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OE105_11275	COG0671	phosphoesterase, PA-phosphatase related
OE105_11280	COG4715	Zinc finger, swim domain protein
OE105_11285	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OE105_11300	COG0629	single-stranded DNA binding
OE105_11320	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OE105_11330	COG4786	Flagellar basal body rod
OE105_11335	COG4786	Flagellar basal body rod
OE105_11345	COG1609	Transcriptional regulator
OE105_11350	COG0739	heme binding
OE105_11360	COG0371	Dehydrogenase
OE105_11365	COG2385	sporulation resulting in formation of a cellular spore
OE105_11370	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OE105_11380	COG4836	Membrane
OE105_11385	COG1007	ATP synthesis coupled electron transport
OE105_11395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OE105_11400	COG0713	ATP synthesis coupled electron transport
OE105_11405	COG0839	Belongs to the complex I subunit 6 family
OE105_11420	COG0649	NAD binding
OE105_11425	COG0649	NAD binding
OE105_11430	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OE105_11435	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OE105_11440	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OE105_11445	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OE105_11450	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OE105_11455	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OE105_11460	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OE105_11465	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OE105_11470	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OE105_11475	COG0356	it plays a direct role in the translocation of protons across the membrane
OE105_11485	COG1404	Belongs to the peptidase S8 family
OE105_11490	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
OE105_11495	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OE105_11500	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OE105_11510	COG0698	ribose 5-phosphate isomerase
OE105_11515	COG0840	transmembrane signaling receptor activity
OE105_11525	COG1971	Probably functions as a manganese efflux pump
OE105_11530	COG0009	L-threonylcarbamoyladenylate synthase
OE105_11545	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OE105_11550	COG1435	thymidine kinase activity
OE105_11555	COG0254	rRNA binding
OE105_11560	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OE105_11565	COG1494	fructose-1,6-bisphosphatase
OE105_11570	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OE105_11575	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OE105_11580	COG0191	fructose-bisphosphate aldolase activity
OE105_11585	COG2204	response regulator
OE105_11590	COG4821	SIS domain
OE105_11595	COG0504	CTP synthase activity
OE105_11600	COG3343	RNA polymerase activity
OE105_11605	COG1703	isobutyryl-CoA mutase activity
OE105_11605	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OE105_11605	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OE105_11615	COG1960	acyl-CoA dehydrogenase activity
OE105_11620	COG1960	acyl-CoA dehydrogenase activity
OE105_11625	COG1250	3-hydroxyacyl-CoA dehydrogenase
OE105_11630	COG0183	Belongs to the thiolase family
OE105_11635	COG2181	nitrate reductase activity
OE105_11635	COG0247	lactate metabolic process
OE105_11650	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OE105_11660	COG1994	Peptidase M50
OE105_11665	COG3465	dGTPase activity
OE105_11670	COG1078	dGTPase activity
OE105_11675	COG4844	belongs to the
OE105_11685	COG0095	Lipoate-protein ligase
OE105_11690	COG0280	phosphate acetyltransferase
OE105_11695	COG3253	May function as heme-dependent peroxidase
OE105_11700	COG3773	Cell wall hydrolase
OE105_11710	COG2363	Small membrane protein
OE105_11720	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OE105_11755	COG0351	phosphomethylpyrimidine kinase
OE105_11760	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OE105_11770	COG1363	Peptidase, m42
OE105_11775	COG3314	Sporulation integral membrane protein YlbJ
OE105_11790	COG2188	Transcriptional regulator
OE105_11795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OE105_11800	COG0156	8-amino-7-oxononanoate synthase activity
OE105_11805	COG3279	Response regulator of the LytR AlgR family
OE105_11810	COG0427	acetyl-CoA hydrolase
OE105_11820	COG1253	flavin adenine dinucleotide binding
OE105_11825	COG0589	response to stress
OE105_11830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OE105_11835	COG0601	transmembrane transport
OE105_11840	COG0747	negative chemotaxis
OE105_11845	COG4608	Belongs to the ABC transporter superfamily
OE105_11850	COG0444	Belongs to the ABC transporter superfamily
OE105_11855	COG1442	glycosyl transferase family 8
OE105_11860	COG2195	Cleaves the N-terminal amino acid of tripeptides
OE105_11865	COG0753	catalase activity
OE105_11880	COG1368	sulfuric ester hydrolase activity
OE105_11905	COG1122	ATPase activity
OE105_11920	COG4492	Belongs to the UPF0735 family
OE105_11925	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OE105_11930	COG0739	heme binding
OE105_11940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OE105_11945	COG1174	glycine betaine transport
OE105_11950	COG0517	IMP dehydrogenase activity
OE105_11950	COG1125	glycine betaine transport
OE105_11980	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OE105_11990	COG0456	acetyltransferase
OE105_12000	COG1595	DNA-templated transcription, initiation
OE105_12010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OE105_12015	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
OE105_12030	COG5002	protein histidine kinase activity
OE105_12035	COG0745	RESPONSE REGULATOR receiver
OE105_12050	COG0305	Participates in initiation and elongation during chromosome replication
OE105_12055	COG0359	binds to the 23S rRNA
OE105_12065	COG4241	membrane
OE105_12070	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OE105_12080	COG0360	Binds together with S18 to 16S ribosomal RNA
OE105_12085	COG0012	GTP binding
OE105_12090	COG4481	Protein conserved in bacteria
OE105_12105	COG1475	DNA binding
OE105_12110	COG1192	Involved in chromosome partitioning
OE105_12115	COG1475	DNA binding
OE105_12125	COG0445	tRNA wobble uridine modification
OE105_12130	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OE105_12135	COG1847	R3H domain protein
OE105_12140	COG0706	membrane insertase activity
OE105_12145	COG0594	ribonuclease P activity
OE105_12150	COG0230	Belongs to the bacterial ribosomal protein bL34 family
OE105_12155	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OE105_12160	COG0592	DNA-directed DNA polymerase activity
OE105_12165	COG2501	S4 domain
OE105_12180	COG0187	DNA topoisomerase II activity
OE105_12185	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OE105_12190	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
OE105_12200	COG0516	GMP reductase activity
OE105_12200	COG0517	IMP dehydrogenase activity
OE105_12210	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OE105_12215	COG1428	Deoxynucleoside kinase
OE105_12220	COG1428	Deoxynucleoside kinase
OE105_12225	COG3858	chitin binding
OE105_12225	COG1388	LysM domain
OE105_12230	COG0590	tRNA wobble adenosine to inosine editing
OE105_12240	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OE105_12245	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OE105_12250	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OE105_12255	COG1694	Mazg nucleotide pyrophosphohydrolase
OE105_12315	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OE105_12320	COG3870	Protein conserved in bacteria
OE105_12325	COG1728	Protein conserved in bacteria
OE105_12330	COG0470	DNA polymerase III
OE105_12335	COG1774	PSP1 C-terminal conserved region
OE105_12340	COG4467	Involved in initiation control of chromosome replication
OE105_12345	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
OE105_12355	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OE105_12360	COG2002	toxin-antitoxin pair type II binding
OE105_12370	COG0084	hydrolase, TatD family'
OE105_12375	COG3583	domain protein
OE105_12375	COG3584	3D domain protein
OE105_12380	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OE105_12385	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OE105_12395	COG4466	Protein conserved in bacteria
OE105_12410	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OE105_12415	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OE105_12420	COG0251	oxidation-reduction process
OE105_12425	COG2088	sporulation resulting in formation of a cellular spore
OE105_12430	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OE105_12450	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OE105_12455	COG2002	toxin-antitoxin pair type II binding
OE105_12460	COG2244	polysaccharide biosynthetic process
OE105_12465	COG3956	TIGRFAM MazG family protein
OE105_12470	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OE105_12490	COG1098	S1 RNA binding domain
OE105_12495	COG2208	phosphoserine phosphatase activity
OE105_12500	COG2304	oxidoreductase activity
OE105_12505	COG0515	serine threonine protein kinase
OE105_12510	COG0037	tRNA processing
OE105_12515	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
OE105_12520	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OE105_12525	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OE105_12530	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OE105_12535	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OE105_12545	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OE105_12550	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OE105_12555	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OE105_12560	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OE105_12600	COG3880	PFAM UvrB UvrC protein
OE105_12605	COG3869	Catalyzes the specific phosphorylation of arginine residues in
OE105_12610	COG0542	response to heat
OE105_12615	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OE105_12620	COG4956	integral membrane protein (PIN domain superfamily)
OE105_12625	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
OE105_12630	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OE105_12635	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OE105_12640	COG1045	serine acetyltransferase
OE105_12645	COG0215	cysteine-tRNA ligase activity
OE105_12655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OE105_12660	COG3688	RNA-binding protein containing a PIN domain
OE105_12665	COG1595	DNA-templated transcription, initiation
OE105_12670	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OE105_12675	COG0250	Participates in transcription elongation, termination and antitermination
OE105_12680	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OE105_12685	COG0081	regulation of translation
OE105_12690	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OE105_12695	COG0222	ribosome binding
OE105_12700	COG2813	Specifically methylates the guanine in position
OE105_12705	COG0085	RNA polymerase activity
OE105_12710	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OE105_12715	COG1358	cellular component organization or biogenesis
OE105_12720	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OE105_12725	COG0049	tRNA binding
OE105_12730	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OE105_12735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OE105_12745	COG0051	transcription antitermination factor activity, RNA binding
OE105_12750	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OE105_12760	COG0089	rRNA binding
OE105_12765	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OE105_12770	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OE105_12780	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OE105_12785	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OE105_12790	COG0255	Belongs to the universal ribosomal protein uL29 family
OE105_12800	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OE105_12805	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OE105_12810	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OE105_12815	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OE105_12820	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OE105_12825	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OE105_12830	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OE105_12835	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OE105_12840	COG1841	ribosomal large subunit assembly
OE105_12845	COG0200	Binds to the 23S rRNA
OE105_12850	COG0201	protein transport
OE105_12855	COG0563	adenylate kinase activity
OE105_12860	COG2163	COG2163 Ribosomal protein L14E L6E L27E
OE105_12865	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OE105_12870	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OE105_12875	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OE105_12880	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OE105_12885	COG0202	RNA polymerase activity
OE105_12890	COG0203	ribosomal protein L17
OE105_12895	COG1122	ATPase activity
OE105_12905	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OE105_12910	COG0101	tRNA pseudouridine synthase activity
OE105_12915	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OE105_12920	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OE105_12940	COG1609	Transcriptional regulator
OE105_12960	COG1175	transmembrane transport
OE105_12975	COG1940	carbohydrate kinase activity
OE105_12980	COG2272	Belongs to the type-B carboxylesterase lipase family
OE105_12985	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OE105_13000	COG0477	Major facilitator Superfamily
OE105_13005	COG0860	N-Acetylmuramoyl-L-alanine amidase
OE105_13010	COG0489	protein tyrosine kinase activity
OE105_13020	COG2194	sulfuric ester hydrolase activity
OE105_13025	COG0726	polysaccharide deacetylase
OE105_13095	COG1595	DNA-templated transcription, initiation
OE105_13100	COG5662	AntiSigma factor
OE105_13105	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OE105_13110	COG4856	YbbR-like protein
OE105_13115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OE105_13120	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OE105_13165	COG1725	Transcriptional regulator
OE105_13185	COG3479	Phenolic acid decarboxylase
OE105_13190	COG1695	Transcriptional regulator
OE105_13195	COG1959	2 iron, 2 sulfur cluster binding
OE105_13210	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OE105_13220	COG3739	integral membrane protein
OE105_13230	COG0840	transmembrane signaling receptor activity
OE105_13240	COG3290	protein histidine kinase activity
OE105_13240	COG0840	transmembrane signaling receptor activity
OE105_13245	COG1595	DNA-templated transcription, initiation
OE105_13260	COG0628	permease
OE105_13265	COG0390	transport system, permease component
OE105_13270	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OE105_13275	COG0730	response to heat
OE105_13285	COG1846	Transcriptional regulator
OE105_13320	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OE105_13325	COG2340	Cysteine-rich secretory protein family
OE105_13335	COG0733	neurotransmitter:sodium symporter activity
OE105_13345	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OE105_13355	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OE105_13375	COG0745	RESPONSE REGULATOR receiver
OE105_13380	COG5002	protein histidine kinase activity
OE105_13380	COG3850	Histidine kinase
OE105_13385	COG0840	transmembrane signaling receptor activity
OE105_13395	COG3842	ATPase activity
OE105_13400	COG1176	ABC-type spermidine putrescine transport system, permease component I
OE105_13405	COG1177	transmembrane transport
OE105_13420	COG4086	secreted protein
OE105_13425	COG0840	transmembrane signaling receptor activity
OE105_13425	COG5278	phosphoserine phosphatase activity
OE105_13440	COG1686	Belongs to the peptidase S11 family
OE105_13445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OE105_13450	COG0601	transmembrane transport
OE105_13460	COG4608	Belongs to the ABC transporter superfamily
OE105_13465	COG0444	Belongs to the ABC transporter superfamily
OE105_13480	COG4145	pantothenate transmembrane transporter activity
OE105_13485	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OE105_13490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OE105_13495	COG0673	inositol 2-dehydrogenase activity
OE105_13505	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OE105_13525	COG1482	cell wall glycoprotein biosynthetic process
OE105_13530	COG1940	carbohydrate kinase activity
OE105_13535	COG1136	(ABC) transporter
OE105_13550	COG1131	(ABC) transporter
OE105_13560	COG1940	carbohydrate kinase activity
OE105_13570	COG2972	Histidine kinase
OE105_13575	COG2207	Transcriptional regulator
OE105_13575	COG4753	response regulator
OE105_13585	COG1175	transmembrane transport
OE105_13595	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OE105_13600	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OE105_13605	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
OE105_13615	COG1609	Transcriptional regulator
OE105_13635	COG1609	Transcriptional regulator
OE105_13640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OE105_13650	COG1129	ABC transporter
OE105_13655	COG1172	Belongs to the binding-protein-dependent transport system permease family
OE105_13660	COG1879	ABC-type sugar transport system periplasmic component
OE105_13670	COG1136	(ABC) transporter
OE105_13675	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
OE105_13680	COG3853	Toxic anion resistance protein (TelA)
OE105_13685	COG0772	Belongs to the SEDS family
OE105_13690	COG1253	flavin adenine dinucleotide binding
OE105_13695	COG2239	Acts as a magnesium transporter
OE105_13705	COG1181	Belongs to the D-alanine--D-alanine ligase family
OE105_13710	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OE105_13720	COG0513	Belongs to the DEAD box helicase family
OE105_13725	COG3402	PFAM membrane-flanked domain
OE105_13730	COG3428	Bacterial PH domain
OE105_13740	COG0736	holo-[acyl-carrier-protein] synthase activity
OE105_13745	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OE105_13755	COG0864	Transcriptional regulator
OE105_13760	COG2337	Toxic component of a toxin-antitoxin (TA) module
OE105_13765	COG2183	response to ionizing radiation
OE105_13770	COG1595	DNA-templated transcription, initiation
OE105_13785	COG3091	SprT-like family
OE105_13835	COG0802	atpase or kinase
OE105_13840	COG1214	PFAM Peptidase M22, glycoprotease
OE105_13845	COG0456	acetyltransferase
OE105_13850	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OE105_13855	COG0488	(ABC) transporter
OE105_13860	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OE105_13865	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes