locus-tag	class	description
HRJ37_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HRJ37_00010	COG0592	DNA-directed DNA polymerase activity
HRJ37_00015	COG2501	S4 domain
HRJ37_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HRJ37_00030	COG0187	DNA topoisomerase II activity
HRJ37_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HRJ37_00070	COG0516	GMP reductase activity
HRJ37_00070	COG0517	IMP dehydrogenase activity
HRJ37_00075	COG1686	Belongs to the peptidase S11 family
HRJ37_00085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HRJ37_00090	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HRJ37_00095	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HRJ37_00100	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HRJ37_00105	COG0840	transmembrane signaling receptor activity
HRJ37_00115	COG1428	Deoxynucleoside kinase
HRJ37_00120	COG1428	Deoxynucleoside kinase
HRJ37_00125	COG1388	LysM domain
HRJ37_00125	COG3858	chitin binding
HRJ37_00130	COG1335	isochorismatase
HRJ37_00135	COG0590	tRNA wobble adenosine to inosine editing
HRJ37_00145	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HRJ37_00150	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HRJ37_00155	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HRJ37_00200	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HRJ37_00205	COG3853	Toxic anion resistance protein (TelA)
HRJ37_00210	COG1982	Orn Lys Arg decarboxylase major
HRJ37_00215	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HRJ37_00220	COG3870	Protein conserved in bacteria
HRJ37_00225	COG1728	Protein conserved in bacteria
HRJ37_00230	COG0470	DNA polymerase III
HRJ37_00235	COG1774	PSP1 C-terminal conserved region
HRJ37_00240	COG4467	Involved in initiation control of chromosome replication
HRJ37_00245	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HRJ37_00250	COG2827	Endonuclease containing a URI domain
HRJ37_00255	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HRJ37_00260	COG2002	toxin-antitoxin pair type II binding
HRJ37_00265	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HRJ37_00265	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HRJ37_00270	COG0084	hydrolase, TatD family'
HRJ37_00275	COG3583	domain protein
HRJ37_00275	COG3584	3D domain protein
HRJ37_00280	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HRJ37_00285	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HRJ37_00295	COG4466	Protein conserved in bacteria
HRJ37_00305	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HRJ37_00310	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HRJ37_00315	COG0251	oxidation-reduction process
HRJ37_00320	COG2088	sporulation resulting in formation of a cellular spore
HRJ37_00330	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HRJ37_00335	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HRJ37_00340	COG0193	aminoacyl-tRNA hydrolase activity
HRJ37_00350	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HRJ37_00355	COG2002	toxin-antitoxin pair type II binding
HRJ37_00360	COG2244	polysaccharide biosynthetic process
HRJ37_00365	COG3956	TIGRFAM MazG family protein
HRJ37_00370	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HRJ37_00385	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HRJ37_00390	COG1098	S1 RNA binding domain
HRJ37_00405	COG2208	phosphoserine phosphatase activity
HRJ37_00410	COG2304	oxidoreductase activity
HRJ37_00415	COG0515	serine threonine protein kinase
HRJ37_00420	COG0037	tRNA processing
HRJ37_00430	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HRJ37_00435	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HRJ37_00440	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HRJ37_00445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HRJ37_00450	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HRJ37_00455	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HRJ37_00460	COG0512	Glutamine amidotransferase of anthranilate synthase
HRJ37_00465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HRJ37_00470	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HRJ37_00475	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HRJ37_00480	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HRJ37_00485	COG1396	sequence-specific DNA binding
HRJ37_00490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HRJ37_00495	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HRJ37_00575	COG4463	regulation of RNA biosynthetic process
HRJ37_00580	COG3880	PFAM UvrB UvrC protein
HRJ37_00585	COG3869	Catalyzes the specific phosphorylation of arginine residues in
HRJ37_00590	COG0542	response to heat
HRJ37_00595	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HRJ37_00600	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HRJ37_00605	COG4956	integral membrane protein (PIN domain superfamily)
HRJ37_00610	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HRJ37_00615	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HRJ37_00620	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HRJ37_00625	COG1045	serine acetyltransferase
HRJ37_00630	COG0215	cysteine-tRNA ligase activity
HRJ37_00635	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HRJ37_00640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HRJ37_00645	COG3688	RNA-binding protein containing a PIN domain
HRJ37_00650	COG1595	DNA-templated transcription, initiation
HRJ37_00655	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HRJ37_00660	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HRJ37_00665	COG0250	Participates in transcription elongation, termination and antitermination
HRJ37_00675	COG0081	regulation of translation
HRJ37_00680	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HRJ37_00685	COG0222	ribosome binding
HRJ37_00690	COG2813	Specifically methylates the guanine in position
HRJ37_00695	COG0085	RNA polymerase activity
HRJ37_00700	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HRJ37_00705	COG1358	cellular component organization or biogenesis
HRJ37_00710	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HRJ37_00715	COG0049	tRNA binding
HRJ37_00720	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HRJ37_00725	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HRJ37_00730	COG0596	Alpha beta hydrolase
HRJ37_00740	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HRJ37_00745	COG0088	Forms part of the polypeptide exit tunnel
HRJ37_00750	COG0089	rRNA binding
HRJ37_00755	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HRJ37_00760	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HRJ37_00765	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HRJ37_00770	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HRJ37_00775	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HRJ37_00780	COG0255	Belongs to the universal ribosomal protein uL29 family
HRJ37_00785	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HRJ37_00790	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HRJ37_00795	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HRJ37_00800	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HRJ37_00805	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HRJ37_00810	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HRJ37_00815	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HRJ37_00820	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HRJ37_00825	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HRJ37_00830	COG1841	ribosomal large subunit assembly
HRJ37_00835	COG0200	Binds to the 23S rRNA
HRJ37_00840	COG0201	protein transport
HRJ37_00845	COG0563	adenylate kinase activity
HRJ37_00850	COG0024	Methionine aminopeptidase
HRJ37_00855	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HRJ37_00860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HRJ37_00865	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HRJ37_00870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HRJ37_00875	COG0202	RNA polymerase activity
HRJ37_00880	COG0203	ribosomal protein L17
HRJ37_00885	COG1122	ATPase activity
HRJ37_00890	COG1122	ATPase activity
HRJ37_00895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HRJ37_00900	COG0101	tRNA pseudouridine synthase activity
HRJ37_00905	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HRJ37_00910	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HRJ37_00915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HRJ37_00940	COG0860	N-Acetylmuramoyl-L-alanine amidase
HRJ37_00945	COG0489	protein tyrosine kinase activity
HRJ37_00955	COG2194	sulfuric ester hydrolase activity
HRJ37_00960	COG0726	polysaccharide deacetylase
HRJ37_00990	COG0659	secondary active sulfate transmembrane transporter activity
HRJ37_00995	COG0385	Bile acid
HRJ37_01000	COG3876	Protein conserved in bacteria
HRJ37_01005	COG1472	Belongs to the glycosyl hydrolase 3 family
HRJ37_01010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HRJ37_01015	COG1263	PTS System
HRJ37_01015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HRJ37_01020	COG1737	Transcriptional regulator
HRJ37_01025	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HRJ37_01060	COG1595	DNA-templated transcription, initiation
HRJ37_01065	COG5662	AntiSigma factor
HRJ37_01070	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HRJ37_01075	COG4856	YbbR-like protein
HRJ37_01080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HRJ37_01085	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HRJ37_01100	COG1131	(ABC) transporter
HRJ37_01110	COG1136	(ABC) transporter
HRJ37_01120	COG1695	Transcriptional regulator
HRJ37_01130	COG1131	(ABC) transporter
HRJ37_01140	COG1413	lyase activity
HRJ37_01145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HRJ37_01155	COG2311	Membrane
HRJ37_01175	COG1476	TRANSCRIPTIONal
HRJ37_01185	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HRJ37_01190	COG2207	Transcriptional regulator
HRJ37_01195	COG1309	transcriptional regulator
HRJ37_01210	COG1113	amino acid transport
HRJ37_01215	COG0584	glycerophosphoryl diester phosphodiesterase
HRJ37_01220	COG2271	Major facilitator Superfamily
HRJ37_01230	COG1331	Highly conserved protein containing a thioredoxin domain
HRJ37_01240	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HRJ37_01255	COG1937	Protein conserved in bacteria
HRJ37_01260	COG2210	Belongs to the sulfur carrier protein TusA family
HRJ37_01270	COG0425	Belongs to the sulfur carrier protein TusA family
HRJ37_01270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HRJ37_01275	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HRJ37_01275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HRJ37_01280	COG0425	Belongs to the sulfur carrier protein TusA family
HRJ37_01285	COG0730	response to heat
HRJ37_01295	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HRJ37_01300	COG2814	Major facilitator Superfamily
HRJ37_01325	COG1846	Transcriptional regulator
HRJ37_01330	COG1683	Conserved Protein
HRJ37_01340	COG0656	L-ascorbic acid biosynthetic process
HRJ37_01345	COG0371	Dehydrogenase
HRJ37_01355	COG0531	amino acid
HRJ37_01365	COG3711	transcriptional antiterminator
HRJ37_01370	COG2190	(PTS) system
HRJ37_01370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HRJ37_01370	COG1263	PTS System
HRJ37_01375	COG2723	6-phospho-beta-galactosidase activity
HRJ37_01390	COG3711	transcriptional antiterminator
HRJ37_01390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HRJ37_01395	COG1940	carbohydrate kinase activity
HRJ37_01400	COG0383	alpha-mannosidase activity
HRJ37_01405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HRJ37_01410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HRJ37_01415	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HRJ37_01415	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HRJ37_01420	COG1404	Belongs to the peptidase S8 family
HRJ37_01440	COG0833	amino acid
HRJ37_01445	COG2040	homocysteine
HRJ37_01450	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HRJ37_01455	COG1695	Transcriptional regulator
HRJ37_01470	COG2814	Major facilitator Superfamily
HRJ37_01475	COG0456	acetyltransferase
HRJ37_01490	COG1404	Belongs to the peptidase S8 family
HRJ37_01500	COG1309	transcriptional regulator
HRJ37_01505	COG1917	Cupin 2, conserved barrel domain protein
HRJ37_01510	COG1063	alcohol dehydrogenase
HRJ37_01515	COG1846	Transcriptional regulator
HRJ37_01520	COG0318	PFAM AMP-dependent synthetase and ligase
HRJ37_01525	COG0531	amino acid
HRJ37_01535	COG0596	Alpha beta hydrolase
HRJ37_01540	COG1115	amino acid carrier protein
HRJ37_01545	COG2066	Belongs to the glutaminase family
HRJ37_01550	COG4191	Histidine kinase
HRJ37_01555	COG0784	Response regulator, receiver
HRJ37_01560	COG1405	negative regulation of cell septum assembly
HRJ37_01560	COG3012	SEC-C Motif Domain Protein
HRJ37_01570	COG0667	Aldo Keto reductase
HRJ37_01575	COG3290	protein histidine kinase activity
HRJ37_01580	COG3279	Response regulator of the LytR AlgR family
HRJ37_01585	COG4555	ABC transporter
HRJ37_01590	COG1668	transmembrane transport
HRJ37_01605	COG3773	Cell wall hydrolase
HRJ37_01610	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ37_01620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HRJ37_01625	COG2310	stress, protein
HRJ37_01630	COG2310	stress, protein
HRJ37_01635	COG2310	stress, protein
HRJ37_01640	COG0861	Integral membrane protein TerC family
HRJ37_01670	COG3853	Toxic anion resistance protein (TelA)
HRJ37_01675	COG4175	Glycine betaine
HRJ37_01675	COG0517	IMP dehydrogenase activity
HRJ37_01680	COG4176	ABC-type proline glycine betaine transport system permease component
HRJ37_01685	COG2113	Glycine betaine
HRJ37_01700	COG1473	amidohydrolase
HRJ37_01705	COG1288	antiporter activity
HRJ37_01710	COG0039	L-malate dehydrogenase activity
HRJ37_01715	COG1620	l-lactate permease
HRJ37_01720	COG1609	Transcriptional regulator
HRJ37_01725	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HRJ37_01730	COG0561	phosphatase activity
HRJ37_01735	COG0673	inositol 2-dehydrogenase activity
HRJ37_01740	COG0738	Major facilitator superfamily
HRJ37_01745	COG1280	lysine exporter protein (LysE YggA)
HRJ37_01760	COG3403	YqcI/YcgG family
HRJ37_01765	COG1113	amino acid transport
HRJ37_01770	COG3665	Urea carboxylase-associated protein
HRJ37_01775	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HRJ37_01785	COG1012	belongs to the aldehyde dehydrogenase family
HRJ37_01790	COG0710	3-dehydroquinate dehydratase activity
HRJ37_01795	COG0028	Belongs to the TPP enzyme family
HRJ37_01805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HRJ37_01810	COG2271	Major facilitator Superfamily
HRJ37_01825	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HRJ37_01835	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HRJ37_01845	COG0477	Major facilitator Superfamily
HRJ37_01850	COG2226	methyltransferase
HRJ37_01855	COG0583	DNA-binding transcription factor activity
HRJ37_01865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HRJ37_01870	COG3458	cephalosporin-C deacetylase activity
HRJ37_01880	COG3541	Predicted nucleotidyltransferase
HRJ37_01885	COG0506	proline dehydrogenase activity
HRJ37_01890	COG1012	belongs to the aldehyde dehydrogenase family
HRJ37_01895	COG2508	Transcriptional regulator
HRJ37_01900	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HRJ37_01905	COG0765	amino acid transport
HRJ37_01910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HRJ37_01920	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HRJ37_01925	COG1522	sequence-specific DNA binding
HRJ37_01930	COG2746	aminoglycoside 3-N-acetyltransferase activity
HRJ37_01940	COG3290	protein histidine kinase activity
HRJ37_01940	COG0840	transmembrane signaling receptor activity
HRJ37_01945	COG3209	COG3209 Rhs family protein
HRJ37_01965	COG3842	ATPase activity
HRJ37_01970	COG1176	ABC-type spermidine putrescine transport system, permease component I
HRJ37_01980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HRJ37_01985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HRJ37_01990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HRJ37_02005	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HRJ37_02010	COG4555	ABC transporter
HRJ37_02020	COG0697	spore germination
HRJ37_02025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HRJ37_02035	COG2207	Transcriptional regulator
HRJ37_02035	COG3708	Transcriptional regulator
HRJ37_02045	COG2364	Membrane
HRJ37_02050	COG0737	Belongs to the 5'-nucleotidase family
HRJ37_02055	COG3764	Sortase (surface protein transpeptidase)
HRJ37_02060	COG2002	toxin-antitoxin pair type II binding
HRJ37_02065	COG1126	abc transporter atp-binding protein
HRJ37_02070	COG0765	amino acid transport
HRJ37_02075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HRJ37_02080	COG0412	Dienelactone hydrolase
HRJ37_02085	COG0833	amino acid
HRJ37_02095	COG3104	oligopeptide transport
HRJ37_02100	COG5434	Belongs to the glycosyl hydrolase 28 family
HRJ37_02105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HRJ37_02110	COG0456	acetyltransferase
HRJ37_02115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HRJ37_02120	COG0765	amino acid transport
HRJ37_02125	COG1126	abc transporter atp-binding protein
HRJ37_02130	COG1473	amidohydrolase
HRJ37_02135	COG2079	MmgE PrpD family protein
HRJ37_02145	COG0745	RESPONSE REGULATOR receiver
HRJ37_02150	COG5002	protein histidine kinase activity
HRJ37_02150	COG3850	Histidine kinase
HRJ37_02155	COG1366	Belongs to the anti-sigma-factor antagonist family
HRJ37_02160	COG0527	aspartate kinase activity
HRJ37_02165	COG2814	Major facilitator Superfamily
HRJ37_02170	COG1309	transcriptional regulator
HRJ37_02180	COG0640	Transcriptional regulator
HRJ37_02190	COG0583	DNA-binding transcription factor activity
HRJ37_02195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HRJ37_02200	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HRJ37_02205	COG0531	amino acid
HRJ37_02210	COG1012	belongs to the aldehyde dehydrogenase family
HRJ37_02215	COG2249	NAD(P)H dehydrogenase (quinone) activity
HRJ37_02220	COG4549	nuclear export factor GLE1
HRJ37_02225	COG2372	response to copper ion
HRJ37_02225	COG1276	copper resistance
HRJ37_02230	COG2213	PTS system mannitol-specific
HRJ37_02235	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HRJ37_02240	COG0246	Mannitol dehydrogenase
HRJ37_02245	COG0840	transmembrane signaling receptor activity
HRJ37_02280	COG0346	lactoylglutathione lyase activity
HRJ37_02290	COG0561	phosphatase activity
HRJ37_02305	COG0457	Tetratricopeptide repeat
HRJ37_02310	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
HRJ37_02315	COG1914	H( )-stimulated, divalent metal cation uptake system
HRJ37_02320	COG4336	lyase activity
HRJ37_02325	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HRJ37_02330	COG1984	allophanate hydrolase subunit 2
HRJ37_02335	COG1414	Transcriptional regulator
HRJ37_02340	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HRJ37_02345	COG2755	lipolytic protein G-D-S-L family
HRJ37_02355	COG3711	transcriptional antiterminator
HRJ37_02360	COG2226	methyltransferase
HRJ37_02365	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ37_02370	COG3871	stress protein (general stress protein 26)
HRJ37_02390	COG2814	Major facilitator Superfamily
HRJ37_02395	COG1802	Transcriptional regulator
HRJ37_02400	COG1917	Cupin 2, conserved barrel domain protein
HRJ37_02400	COG2207	Transcriptional regulator
HRJ37_02405	COG0697	spore germination
HRJ37_02410	COG0473	3-isopropylmalate dehydrogenase activity
HRJ37_02415	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HRJ37_02415	COG0551	DNA topoisomerase type I activity
HRJ37_02420	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HRJ37_02425	COG3706	GGDEF domain
HRJ37_02430	COG5298	Protein conserved in bacteria
HRJ37_02435	COG1215	transferase activity, transferring glycosyl groups
HRJ37_02445	COG0531	amino acid
HRJ37_02450	COG0028	Belongs to the TPP enzyme family
HRJ37_02455	COG5444	nuclease activity
HRJ37_02485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HRJ37_02490	COG1914	H( )-stimulated, divalent metal cation uptake system
HRJ37_02495	COG2261	transglycosylase associated protein
HRJ37_02500	COG2217	Heavy metal translocating P-type atpase
HRJ37_02505	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HRJ37_02510	COG3290	protein histidine kinase activity
HRJ37_02515	COG4565	transcriptional regulatory protein
HRJ37_02520	COG1301	dicarboxylic acid transport
HRJ37_02525	COG0628	permease
HRJ37_02530	COG1301	dicarboxylic acid transport
HRJ37_02535	COG1131	(ABC) transporter
HRJ37_02540	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HRJ37_02555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HRJ37_02560	COG1181	Belongs to the D-alanine--D-alanine ligase family
HRJ37_02565	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HRJ37_02580	COG0513	Belongs to the DEAD box helicase family
HRJ37_02585	COG3402	PFAM membrane-flanked domain
HRJ37_02590	COG3428	Bacterial PH domain
HRJ37_02595	COG0705	Rhomboid family
HRJ37_02600	COG0736	holo-[acyl-carrier-protein] synthase activity
HRJ37_02605	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HRJ37_02610	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HRJ37_02615	COG0864	Transcriptional regulator
HRJ37_02620	COG2337	Toxic component of a toxin-antitoxin (TA) module
HRJ37_02625	COG1366	Belongs to the anti-sigma-factor antagonist family
HRJ37_02630	COG1366	Belongs to the anti-sigma-factor antagonist family
HRJ37_02635	COG2172	sigma factor antagonist activity
HRJ37_02640	COG2208	phosphoserine phosphatase activity
HRJ37_02645	COG1366	Belongs to the anti-sigma-factor antagonist family
HRJ37_02650	COG2172	sigma factor antagonist activity
HRJ37_02655	COG1191	sigma factor activity
HRJ37_02660	COG2208	phosphoserine phosphatase activity
HRJ37_02665	COG2183	response to ionizing radiation
HRJ37_02675	COG3091	SprT-like family
HRJ37_02680	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HRJ37_02685	COG0022	dehydrogenase e1 component
HRJ37_02690	COG0508	dehydrogenase complex catalyzes the overall conversion of
HRJ37_02695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HRJ37_02700	COG3284	Transcriptional regulator
HRJ37_02740	COG1309	transcriptional regulator
HRJ37_02745	COG0596	Alpha beta hydrolase
HRJ37_02745	COG0508	dehydrogenase complex catalyzes the overall conversion of
HRJ37_02750	COG1902	pentaerythritol trinitrate reductase activity
HRJ37_02755	COG0300	oxidoreductase activity
HRJ37_02765	COG1063	alcohol dehydrogenase
HRJ37_02770	COG1278	Cold shock
HRJ37_02775	COG1329	Transcriptional regulator
HRJ37_02780	COG1064	alcohol dehydrogenase
HRJ37_02785	COG0789	Transcriptional regulator
HRJ37_02800	COG0477	Major facilitator Superfamily
HRJ37_02815	COG4221	oxidoreductase activity
HRJ37_02825	COG0252	asparaginase activity
HRJ37_02830	COG2267	carboxylic ester hydrolase activity
HRJ37_02850	COG2814	Major facilitator Superfamily
HRJ37_02855	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HRJ37_02860	COG2409	Drug exporters of the RND superfamily
HRJ37_02865	COG4585	Histidine kinase
HRJ37_02870	COG2197	response regulator
HRJ37_02915	COG1309	transcriptional regulator
HRJ37_02920	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HRJ37_02925	COG1846	Transcriptional regulator
HRJ37_02930	COG0778	Nitroreductase
HRJ37_02945	COG1396	sequence-specific DNA binding
HRJ37_02955	COG0456	acetyltransferase
HRJ37_02965	COG4122	O-methyltransferase activity
HRJ37_02975	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HRJ37_02980	COG0697	spore germination
HRJ37_02990	COG1301	dicarboxylic acid transport
HRJ37_03030	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HRJ37_03035	COG0802	atpase or kinase
HRJ37_03040	COG1214	PFAM Peptidase M22, glycoprotease
HRJ37_03045	COG0456	acetyltransferase
HRJ37_03050	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HRJ37_03055	COG0488	(ABC) transporter
HRJ37_03060	COG0315	cyclic pyranopterin monophosphate synthase activity
HRJ37_03065	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HRJ37_03070	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HRJ37_03075	COG0805	protein transport
HRJ37_03090	COG1266	CAAX protease self-immunity
HRJ37_03095	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HRJ37_03100	COG0459	protein refolding
HRJ37_03105	COG1846	Transcriptional regulator
HRJ37_03110	COG0456	acetyltransferase
HRJ37_03115	COG2808	Putative FMN-binding domain
HRJ37_03145	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HRJ37_03150	COG0823	Involved in the tonB-independent uptake of proteins
HRJ37_03160	COG2132	Multicopper oxidase
HRJ37_03165	COG1113	amino acid transport
HRJ37_03170	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HRJ37_03175	COG0714	Associated with various cellular activities
HRJ37_03180	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
HRJ37_03185	COG1305	Transglutaminase-like
HRJ37_03190	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HRJ37_03190	COG0519	Catalyzes the synthesis of GMP from XMP
HRJ37_03195	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HRJ37_03205	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HRJ37_03235	COG3279	Response regulator of the LytR AlgR family
HRJ37_03255	COG1595	DNA-templated transcription, initiation
HRJ37_03265	COG2814	Major facilitator Superfamily
HRJ37_03270	COG0583	DNA-binding transcription factor activity
HRJ37_03275	COG2252	PERMEase
HRJ37_03285	COG5583	Uncharacterized small protein (DUF2292)
HRJ37_03290	COG3064	Membrane
HRJ37_03295	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
HRJ37_03305	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HRJ37_03310	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HRJ37_03315	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HRJ37_03320	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HRJ37_03325	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HRJ37_03330	COG0047	phosphoribosylformylglycinamidine synthase activity
HRJ37_03335	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HRJ37_03340	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HRJ37_03345	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HRJ37_03350	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HRJ37_03355	COG0138	bifunctional purine biosynthesis protein purh
HRJ37_03360	COG0151	Belongs to the GarS family
HRJ37_03380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HRJ37_03385	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HRJ37_03390	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HRJ37_03395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HRJ37_03405	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HRJ37_03410	COG4496	protein, YerC YecD
HRJ37_03420	COG0069	glutamate synthase activity
HRJ37_03435	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HRJ37_03440	COG0210	DNA helicase
HRJ37_03445	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HRJ37_03450	COG4851	CamS sex pheromone cAM373 precursor
HRJ37_03455	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HRJ37_03460	COG1285	pathogenesis
HRJ37_03465	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HRJ37_03470	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HRJ37_03475	COG0154	amidase activity
HRJ37_03480	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HRJ37_03485	COG1309	transcriptional regulator
HRJ37_03490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HRJ37_03495	COG1957	nucleoside hydrolase
HRJ37_03500	COG1597	lipid kinase activity
HRJ37_03505	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HRJ37_03515	COG5444	nuclease activity
HRJ37_03520	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HRJ37_03535	COG1959	2 iron, 2 sulfur cluster binding
HRJ37_03540	COG0492	ferredoxin-NADP+ reductase activity
HRJ37_03555	COG1486	melibiose metabolic process
HRJ37_03565	COG2211	Major facilitator Superfamily
HRJ37_03595	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HRJ37_03600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HRJ37_03605	COG1442	glycosyl transferase family 8
HRJ37_03610	COG1216	Glycosyl transferase, family 2
HRJ37_03615	COG1442	glycosyl transferase family 8
HRJ37_03620	COG2223	nitrite transmembrane transporter activity
HRJ37_03630	COG0471	metal ion transport
HRJ37_03645	COG0071	Belongs to the small heat shock protein (HSP20) family
HRJ37_03660	COG0531	amino acid
HRJ37_03665	COG0463	Glycosyl transferase, family 2
HRJ37_03665	COG0457	Tetratricopeptide repeat
HRJ37_03670	COG0488	(ABC) transporter
HRJ37_03675	COG1469	GTP cyclohydrolase I activity
HRJ37_03680	COG0789	Transcriptional regulator
HRJ37_03685	COG2814	Major facilitator Superfamily
HRJ37_03690	COG0488	(ABC) transporter
HRJ37_03695	COG0513	Belongs to the DEAD box helicase family
HRJ37_03700	COG2130	NADP-dependent
HRJ37_03720	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HRJ37_03720	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HRJ37_03725	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HRJ37_03735	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HRJ37_03735	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HRJ37_03745	COG3290	protein histidine kinase activity
HRJ37_03750	COG4565	transcriptional regulatory protein
HRJ37_03755	COG3181	Tripartite tricarboxylate transporter family receptor
HRJ37_03760	COG2851	Citrate transporter
HRJ37_03770	COG3479	Phenolic acid decarboxylase
HRJ37_03775	COG1695	Transcriptional regulator
HRJ37_03780	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HRJ37_03790	COG1254	Belongs to the acylphosphatase family
HRJ37_03795	COG2258	MOSC domain
HRJ37_03810	COG0024	Methionine aminopeptidase
HRJ37_03815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HRJ37_03815	COG1263	PTS System
HRJ37_03820	COG3739	integral membrane protein
HRJ37_03835	COG1368	sulfuric ester hydrolase activity
HRJ37_03840	COG0076	glutamate decarboxylase activity
HRJ37_03845	COG0840	transmembrane signaling receptor activity
HRJ37_03855	COG1263	PTS System
HRJ37_03855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HRJ37_03860	COG0366	Alpha amylase catalytic
HRJ37_03865	COG2188	Transcriptional regulator
HRJ37_03875	COG0737	Belongs to the 5'-nucleotidase family
HRJ37_03880	COG0693	protein deglycase activity
HRJ37_03885	COG4840	Belongs to the UPF0435 family
HRJ37_03890	COG1115	amino acid carrier protein
HRJ37_03895	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HRJ37_03900	COG4980	gas vesicle protein
HRJ37_03905	COG1295	ribonuclease BN
HRJ37_03915	COG0477	Major facilitator Superfamily
HRJ37_03925	COG0387	Pfam Sodium calcium exchanger
HRJ37_03935	COG0217	transcriptional regulatory protein
HRJ37_03945	COG0668	transmembrane transport
HRJ37_03950	COG0535	radical SAM domain protein
HRJ37_03960	COG0726	polysaccharide deacetylase
HRJ37_03970	COG0598	Magnesium transport protein CorA
HRJ37_03980	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HRJ37_03985	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HRJ37_04015	COG0789	Transcriptional regulator
HRJ37_04020	COG2814	Major facilitator Superfamily
HRJ37_04070	COG2076	Multidrug Resistance protein
HRJ37_04075	COG2076	Multidrug Resistance protein
HRJ37_04080	COG1309	transcriptional regulator
HRJ37_04090	COG4637	Psort location Cytoplasmic, score
HRJ37_04095	COG2755	lipolytic protein G-D-S-L family
HRJ37_04100	COG0492	ferredoxin-NADP+ reductase activity
HRJ37_04105	COG2169	Transcriptional regulator
HRJ37_04110	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HRJ37_04115	COG1132	(ABC) transporter
HRJ37_04120	COG1742	UPF0060 membrane protein
HRJ37_04125	COG1595	DNA-templated transcription, initiation
HRJ37_04145	COG2318	DinB family
HRJ37_04155	COG1846	Transcriptional regulator
HRJ37_04160	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HRJ37_04160	COG0392	lysyltransferase activity
HRJ37_04180	COG0778	Nitroreductase
HRJ37_04195	COG1090	epimerase
HRJ37_04200	COG2137	regulation of response to DNA damage stimulus
HRJ37_04225	COG0463	Glycosyl transferase, family 2
HRJ37_04230	COG4485	Bacterial membrane protein, YfhO
HRJ37_04235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HRJ37_04250	COG2140	Oxalate decarboxylase
HRJ37_04260	COG1191	sigma factor activity
HRJ37_04305	COG1988	membrane-bound metal-dependent
HRJ37_04310	COG1194	a g-specific adenine glycosylase
HRJ37_04320	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ37_04335	COG3557	Belongs to the UPF0374 family
HRJ37_04340	COG1132	(ABC) transporter
HRJ37_04345	COG0444	Belongs to the ABC transporter superfamily
HRJ37_04350	COG4608	Belongs to the ABC transporter superfamily
HRJ37_04355	COG0747	negative chemotaxis
HRJ37_04370	COG4129	membrane
HRJ37_04375	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HRJ37_04380	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HRJ37_04385	COG0735	belongs to the Fur family
HRJ37_04540	COG1368	sulfuric ester hydrolase activity
HRJ37_04545	COG0681	Belongs to the peptidase S26 family
HRJ37_04550	COG2873	o-acetylhomoserine
HRJ37_04565	COG1131	(ABC) transporter
HRJ37_04595	COG3382	B3 4 domain protein
HRJ37_04600	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HRJ37_04610	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HRJ37_04615	COG2766	serine protein kinase
HRJ37_04620	COG2718	Belongs to the UPF0229 family
HRJ37_04625	COG1566	PFAM secretion protein HlyD family protein
HRJ37_04630	COG2814	Major facilitator Superfamily
HRJ37_04635	COG0655	NAD(P)H dehydrogenase (quinone) activity
HRJ37_04645	COG1278	Cold shock
HRJ37_04650	COG3706	GGDEF domain
HRJ37_04675	COG5577	PFAM Coat F domain
HRJ37_04680	COG5002	protein histidine kinase activity
HRJ37_04685	COG4085	toxin activity
HRJ37_04685	COG1525	nuclease
HRJ37_04685	COG0737	Belongs to the 5'-nucleotidase family
HRJ37_04690	COG3764	Sortase (surface protein transpeptidase)
HRJ37_04695	COG0564	pseudouridine synthase activity
HRJ37_04705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HRJ37_04710	COG3153	acetyltransferase
HRJ37_04710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HRJ37_04730	COG3835	regulator
HRJ37_04735	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HRJ37_04740	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HRJ37_04745	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HRJ37_04750	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HRJ37_04755	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HRJ37_04760	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HRJ37_04765	COG4585	Histidine kinase
HRJ37_04765	COG2203	Gaf domain
HRJ37_04770	COG2197	response regulator
HRJ37_04785	COG0753	catalase activity
HRJ37_04790	COG1959	2 iron, 2 sulfur cluster binding
HRJ37_04795	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HRJ37_04795	COG1017	nitric oxide dioxygenase activity
HRJ37_04800	COG2719	SpoVR family
HRJ37_04805	COG1785	Belongs to the alkaline phosphatase family
HRJ37_04810	COG1388	LysM domain
HRJ37_04810	COG0791	NLP P60 protein
HRJ37_04825	COG1595	DNA-templated transcription, initiation
HRJ37_04830	COG0204	Acyl-transferase
HRJ37_04835	COG1253	flavin adenine dinucleotide binding
HRJ37_04840	COG0789	Transcriptional regulator
HRJ37_04845	COG1253	flavin adenine dinucleotide binding
HRJ37_04860	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HRJ37_04865	COG0584	glycerophosphoryl diester phosphodiesterase
HRJ37_04875	COG0668	transmembrane transport
HRJ37_04880	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HRJ37_04885	COG0726	polysaccharide deacetylase
HRJ37_04890	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HRJ37_04895	COG0589	response to stress
HRJ37_04900	COG1132	(ABC) transporter
HRJ37_04905	COG1132	(ABC) transporter
HRJ37_04910	COG0702	epimerase
HRJ37_04920	COG3842	ATPase activity
HRJ37_04925	COG2508	Transcriptional regulator
HRJ37_04935	COG0189	ligase activity
HRJ37_04940	COG0189	ligase activity
HRJ37_04945	COG4399	Belongs to the UPF0754 family
HRJ37_04950	COG3679	Belongs to the UPF0342 family
HRJ37_04955	COG0561	phosphatase activity
HRJ37_04960	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HRJ37_04970	COG0475	glutathione-regulated potassium exporter activity
HRJ37_04975	COG0490	domain, Protein
HRJ37_04985	COG1024	Enoyl-CoA hydratase
HRJ37_04995	COG0420	3'-5' exonuclease activity
HRJ37_05000	COG4717	serine-type aminopeptidase activity
HRJ37_05005	COG3481	metal-dependent phosphohydrolase, HD sub domain
HRJ37_05015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HRJ37_05040	COG1846	Transcriptional regulator
HRJ37_05045	COG4980	gas vesicle protein
HRJ37_05060	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HRJ37_05065	COG0537	adenosine 5'-monophosphoramidase activity
HRJ37_05070	COG1131	(ABC) transporter
HRJ37_05075	COG4473	ABC transporter
HRJ37_05085	COG1473	amidohydrolase
HRJ37_05095	COG2329	Antibiotic biosynthesis monooxygenase
HRJ37_05100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HRJ37_05105	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HRJ37_05120	COG1309	transcriptional regulator
HRJ37_05125	COG1511	domain protein
HRJ37_05130	COG1363	Peptidase, m42
HRJ37_05135	COG1301	dicarboxylic acid transport
HRJ37_05145	COG1234	tRNA 3'-trailer cleavage
HRJ37_05150	COG0095	Lipoate-protein ligase
HRJ37_05155	COG0318	PFAM AMP-dependent synthetase and ligase
HRJ37_05165	COG0501	Belongs to the peptidase M48B family
HRJ37_05170	COG1404	Belongs to the peptidase S8 family
HRJ37_05175	COG0406	alpha-ribazole phosphatase activity
HRJ37_05180	COG0840	transmembrane signaling receptor activity
HRJ37_05185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HRJ37_05185	COG0723	plastoquinol--plastocyanin reductase activity
HRJ37_05190	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ37_05200	COG4903	ComK protein
HRJ37_05210	COG2856	Zn peptidase
HRJ37_05220	COG1396	sequence-specific DNA binding
HRJ37_05255	COG5377	YqaJ viral recombinase family
HRJ37_05260	COG3723	Recombinational DNA repair protein, rece pathway
HRJ37_05265	COG3935	DnaD domain protein
HRJ37_05270	COG1484	DNA-dependent DNA replication
HRJ37_05345	COG3677	Transposase
HRJ37_05430	COG5412	phage tail tape measure protein
HRJ37_05430	COG3953	SLT domain
HRJ37_05495	COG1876	peptidase activity
HRJ37_05510	COG0328	RNA-DNA hybrid ribonuclease activity
HRJ37_05510	COG3341	Caulimovirus viroplasmin
HRJ37_05535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HRJ37_05540	COG2814	Major facilitator Superfamily
HRJ37_05545	COG2732	(Barnase) inhibitor
HRJ37_05550	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HRJ37_05555	COG4605	iron ion homeostasis
HRJ37_05560	COG4604	ABC transporter, ATP-binding protein
HRJ37_05565	COG4607	ABC-type enterochelin transport system periplasmic component
HRJ37_05570	COG1316	TRANSCRIPTIONal
HRJ37_05585	COG0398	Pfam SNARE associated Golgi protein
HRJ37_05590	COG0681	Belongs to the peptidase S26 family
HRJ37_05595	COG3180	Ammonia monooxygenase
HRJ37_05610	COG2259	Doxx family
HRJ37_05615	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HRJ37_05620	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
HRJ37_05625	COG1074	ATP-dependent DNA helicase activity
HRJ37_05630	COG0420	3'-5' exonuclease activity
HRJ37_05635	COG0419	ATPase involved in DNA repair
HRJ37_05640	COG1403	HNH endonuclease
HRJ37_05680	COG5337	Spore coat protein CotH
HRJ37_05690	COG0179	Fumarylacetoacetate (FAA) hydrolase
HRJ37_05705	COG0367	asparagine synthase
HRJ37_05720	COG1562	ergosterol biosynthetic process
HRJ37_05725	COG0534	Mate efflux family protein
HRJ37_05730	COG1917	Cupin 2, conserved barrel domain protein
HRJ37_05730	COG2207	Transcriptional regulator
HRJ37_05755	COG0076	glutamate decarboxylase activity
HRJ37_05795	COG0646	methionine synthase
HRJ37_05795	COG1410	methionine synthase
HRJ37_05800	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HRJ37_05800	COG0646	methionine synthase
HRJ37_05805	COG1666	GTP binding
HRJ37_05810	COG2996	Protein conserved in bacteria
HRJ37_05820	COG0840	transmembrane signaling receptor activity
HRJ37_05825	COG1307	EDD domain protein, DegV family
HRJ37_05830	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HRJ37_05850	COG0561	phosphatase activity
HRJ37_05855	COG1073	alpha beta
HRJ37_05860	COG2151	metal-sulfur cluster biosynthetic enzyme
HRJ37_05870	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HRJ37_05875	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HRJ37_05880	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HRJ37_05885	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HRJ37_05890	COG0505	Belongs to the CarA family
HRJ37_05895	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HRJ37_05900	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HRJ37_05910	COG2814	Major facilitator Superfamily
HRJ37_05920	COG2267	carboxylic ester hydrolase activity
HRJ37_05930	COG1744	ABC transporter substrate-binding protein PnrA-like
HRJ37_05945	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HRJ37_05950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HRJ37_05955	COG5504	Zn-dependent protease
HRJ37_05960	COG0444	Belongs to the ABC transporter superfamily
HRJ37_05965	COG4608	Belongs to the ABC transporter superfamily
HRJ37_05975	COG0601	transmembrane transport
HRJ37_05980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HRJ37_05990	COG0180	Tryptophanyl-tRNA synthetase
HRJ37_05995	COG4166	transmembrane transport
HRJ37_06000	COG0601	transmembrane transport
HRJ37_06005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HRJ37_06010	COG0444	Belongs to the ABC transporter superfamily
HRJ37_06015	COG4608	Belongs to the ABC transporter superfamily
HRJ37_06025	COG0456	acetyltransferase
HRJ37_06030	COG1393	Belongs to the ArsC family
HRJ37_06035	COG0861	Integral membrane protein TerC family
HRJ37_06040	COG4862	establishment of competence for transformation
HRJ37_06045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HRJ37_06055	COG1164	Oligoendopeptidase f
HRJ37_06070	COG2346	COG2346, Truncated hemoglobins
HRJ37_06075	COG0741	lytic transglycosylase activity
HRJ37_06080	COG4116	CYTH
HRJ37_06090	COG2357	RelA SpoT domain protein
HRJ37_06095	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HRJ37_06100	COG0564	pseudouridine synthase activity
HRJ37_06105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HRJ37_06110	COG0475	glutathione-regulated potassium exporter activity
HRJ37_06110	COG0569	domain protein
HRJ37_06115	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HRJ37_06120	COG0352	thiamine-phosphate diphosphorylase activity
HRJ37_06130	COG2104	thiamine diphosphate biosynthetic process
HRJ37_06135	COG2022	thiamine diphosphate biosynthetic process
HRJ37_06140	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HRJ37_06145	COG0351	phosphomethylpyrimidine kinase
HRJ37_06150	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HRJ37_06205	COG0210	DNA helicase
HRJ37_06215	COG2153	protein acetylation
HRJ37_06220	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HRJ37_06225	COG2382	esterase
HRJ37_06230	COG0626	cystathionine gamma-synthase activity
HRJ37_06235	COG0626	cystathionine gamma-synthase activity
HRJ37_06290	COG3620	sequence-specific DNA binding
HRJ37_06305	COG0825	malonyl-CoA metabolic process
HRJ37_06330	COG0457	Tetratricopeptide repeat
HRJ37_06380	COG0583	DNA-binding transcription factor activity
HRJ37_06400	COG0583	DNA-binding transcription factor activity
HRJ37_06405	COG2807	transmembrane transport
HRJ37_06440	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HRJ37_06450	COG1309	transcriptional regulator
HRJ37_06460	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HRJ37_06465	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HRJ37_06470	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HRJ37_06475	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HRJ37_06495	COG4195	phage-related replication protein
HRJ37_06500	COG2856	Zn peptidase
HRJ37_06505	COG5632	N-Acetylmuramoyl-L-alanine amidase
HRJ37_06505	COG3409	Peptidoglycan-binding domain 1 protein
HRJ37_06520	COG0306	phosphate transporter
HRJ37_06525	COG1392	Phosphate transport regulator
HRJ37_06535	COG0405	Gamma-glutamyltransferase
HRJ37_06540	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HRJ37_06550	COG4208	sulfate ABC transporter
HRJ37_06555	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HRJ37_06565	COG3775	system Galactitol-specific IIC component
HRJ37_06580	COG1063	alcohol dehydrogenase
HRJ37_06585	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HRJ37_06590	COG0022	dehydrogenase e1 component
HRJ37_06590	COG0508	dehydrogenase complex catalyzes the overall conversion of
HRJ37_06595	COG0508	dehydrogenase complex catalyzes the overall conversion of
HRJ37_06600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HRJ37_06605	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ37_06610	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ37_06615	COG2390	Transcriptional regulator
HRJ37_06625	COG0531	amino acid
HRJ37_06630	COG0346	lactoylglutathione lyase activity
HRJ37_06640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HRJ37_06645	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HRJ37_06650	COG2362	D-Aminopeptidase
HRJ37_06655	COG0601	transmembrane transport
HRJ37_06660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HRJ37_06665	COG0444	Belongs to the ABC transporter superfamily
HRJ37_06670	COG4166	transmembrane transport
HRJ37_06675	COG1619	proteins homologs of microcin C7 resistance protein MccF
HRJ37_06680	COG4948	Mandelate Racemase Muconate Lactonizing
HRJ37_06685	COG0791	NLP P60 protein
HRJ37_06690	COG4608	Belongs to the ABC transporter superfamily
HRJ37_06695	COG1834	amidinotransferase
HRJ37_06700	COG1607	acyl-coa hydrolase
HRJ37_06705	COG1695	Transcriptional regulator
HRJ37_06720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HRJ37_06730	COG2076	Multidrug Resistance protein
HRJ37_06735	COG2076	Multidrug Resistance protein
HRJ37_06745	COG0788	formyltetrahydrofolate deformylase activity
HRJ37_06750	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HRJ37_06755	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HRJ37_06760	COG0457	Tetratricopeptide repeat
HRJ37_06770	COG1764	response to oxidative stress
HRJ37_06775	COG1846	Transcriptional regulator
HRJ37_06780	COG1764	response to oxidative stress
HRJ37_06785	COG0590	tRNA wobble adenosine to inosine editing
HRJ37_06790	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HRJ37_06795	COG1404	Belongs to the peptidase S8 family
HRJ37_06810	COG0745	RESPONSE REGULATOR receiver
HRJ37_06815	COG3850	Histidine kinase
HRJ37_06815	COG5002	protein histidine kinase activity
HRJ37_06820	COG3212	peptidase
HRJ37_06825	COG3212	peptidase
HRJ37_06835	COG2239	Acts as a magnesium transporter
HRJ37_06845	COG0583	DNA-binding transcription factor activity
HRJ37_06855	COG0789	Transcriptional regulator
HRJ37_06870	COG1846	Transcriptional regulator
HRJ37_06875	COG5001	Diguanylate cyclase
HRJ37_06875	COG3300	MHYT domain
HRJ37_06880	COG0586	Pfam SNARE associated Golgi protein
HRJ37_06885	COG0861	Integral membrane protein TerC family
HRJ37_06890	COG1191	sigma factor activity
HRJ37_06910	COG0501	Belongs to the peptidase M48B family
HRJ37_06915	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HRJ37_06920	COG2323	membrane
HRJ37_06935	COG3594	Acyltransferase
HRJ37_06940	COG5002	protein histidine kinase activity
HRJ37_06945	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HRJ37_06950	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HRJ37_06955	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HRJ37_06960	COG0436	Aminotransferase
HRJ37_06965	COG1850	ribulose-bisphosphate carboxylase activity
HRJ37_06970	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HRJ37_06975	COG0235	Class ii aldolase
HRJ37_06980	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HRJ37_06990	COG3852	Histidine kinase
HRJ37_06995	COG1846	Transcriptional regulator
HRJ37_07000	COG1360	Flagellar Motor Protein
HRJ37_07005	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HRJ37_07010	COG0542	response to heat
HRJ37_07015	COG3949	Membrane
HRJ37_07020	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HRJ37_07025	COG0720	synthase
HRJ37_07030	COG0602	queuosine metabolic process
HRJ37_07035	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HRJ37_07045	COG4873	Protein conserved in bacteria
HRJ37_07055	COG3773	Cell wall hydrolase
HRJ37_07060	COG2244	polysaccharide biosynthetic process
HRJ37_07065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HRJ37_07070	COG2217	Heavy metal translocating P-type atpase
HRJ37_07075	COG0006	proline dipeptidase activity
HRJ37_07080	COG1609	Transcriptional regulator
HRJ37_07085	COG3711	transcriptional antiterminator
HRJ37_07090	COG2190	(PTS) system
HRJ37_07090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HRJ37_07090	COG1263	PTS System
HRJ37_07095	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HRJ37_07100	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HRJ37_07110	COG1533	DNA photolyase activity
HRJ37_07115	COG0840	transmembrane signaling receptor activity
HRJ37_07125	COG2084	Dehydrogenase
HRJ37_07130	COG2340	Cysteine-rich secretory protein family
HRJ37_07135	COG0768	penicillin binding
HRJ37_07140	COG4191	Histidine kinase
HRJ37_07145	COG0436	Aminotransferase
HRJ37_07150	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HRJ37_07160	COG1714	RDD family
HRJ37_07170	COG0784	Response regulator, receiver
HRJ37_07170	COG0835	chemotaxis
HRJ37_07190	COG2814	Major facilitator Superfamily
HRJ37_07195	COG1376	ErfK ybiS ycfS ynhG family protein
HRJ37_07200	COG1408	metallophosphoesterase
HRJ37_07205	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ37_07210	COG2200	EAL domain
HRJ37_07215	COG3546	catalase activity
HRJ37_07220	COG4703	Protein of unknown function (DUF1797)
HRJ37_07225	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
HRJ37_07235	COG0517	IMP dehydrogenase activity
HRJ37_07240	COG0583	DNA-binding transcription factor activity
HRJ37_07250	COG0716	FMN binding
HRJ37_07260	COG0716	FMN binding
HRJ37_07265	COG2171	N-acyltransferase activity
HRJ37_07270	COG1473	amidohydrolase
HRJ37_07280	COG0668	transmembrane transport
HRJ37_07285	COG0450	alkyl hydroperoxide reductase
HRJ37_07290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HRJ37_07305	COG0746	molybdenum cofactor guanylyltransferase activity
HRJ37_07310	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HRJ37_07315	COG0303	'Molybdopterin
HRJ37_07320	COG1763	Mo-molybdopterin cofactor biosynthetic process
HRJ37_07325	COG0314	molybdopterin synthase activity
HRJ37_07330	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HRJ37_07345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HRJ37_07350	COG1136	(ABC) transporter
HRJ37_07355	COG0577	efflux transmembrane transporter activity
HRJ37_07360	COG1349	DNA-binding transcription factor activity
HRJ37_07365	COG1105	Belongs to the carbohydrate kinase PfkB family
HRJ37_07370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HRJ37_07370	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HRJ37_07370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HRJ37_07375	COG0681	Belongs to the peptidase S26 family
HRJ37_07385	COG0488	(ABC) transporter
HRJ37_07390	COG2309	aminopeptidase activity
HRJ37_07400	COG1077	Cell shape determining protein MreB Mrl
HRJ37_07405	COG2002	toxin-antitoxin pair type II binding
HRJ37_07410	COG3852	Histidine kinase
HRJ37_07415	COG2105	PFAM AIG2 family protein
HRJ37_07415	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HRJ37_07420	COG0569	domain protein
HRJ37_07425	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HRJ37_07430	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HRJ37_07440	COG0561	phosphatase activity
HRJ37_07445	COG0242	peptide deformylase activity
HRJ37_07460	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HRJ37_07465	COG0022	dehydrogenase e1 component
HRJ37_07470	COG0508	dehydrogenase complex catalyzes the overall conversion of
HRJ37_07475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HRJ37_07480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HRJ37_07490	COG1982	Orn Lys Arg decarboxylase major
HRJ37_07495	COG4476	Belongs to the UPF0223 family
HRJ37_07500	COG4493	Belongs to the UPF0637 family
HRJ37_07510	COG0483	inositol monophosphate 1-phosphatase activity
HRJ37_07525	COG1595	DNA-templated transcription, initiation
HRJ37_07555	COG4896	Protein conserved in bacteria
HRJ37_07565	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HRJ37_07570	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HRJ37_07575	COG2066	Belongs to the glutaminase family
HRJ37_07580	COG4838	Belongs to the UPF0358 family
HRJ37_07585	COG0772	Belongs to the SEDS family
HRJ37_07590	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HRJ37_07600	COG1612	heme a metabolic process
HRJ37_07605	COG0109	protoheme IX farnesyltransferase activity
HRJ37_07610	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HRJ37_07610	COG2010	Cytochrome c
HRJ37_07615	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HRJ37_07620	COG1845	cytochrome c oxidase, subunit III
HRJ37_07625	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HRJ37_07630	COG3336	cytochrome c oxidase
HRJ37_07640	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
HRJ37_07645	COG2340	Cysteine-rich secretory protein family
HRJ37_07665	COG3679	Belongs to the UPF0342 family
HRJ37_07670	COG4471	UPF0298 protein
HRJ37_07675	COG0742	ribosomal rna small subunit methyltransferase
HRJ37_07680	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HRJ37_07685	COG3314	Sporulation integral membrane protein YlbJ
HRJ37_07690	COG1752	Esterase of the alpha-beta hydrolase superfamily
HRJ37_07695	COG3480	Lon protease (S16) C-terminal proteolytic domain
HRJ37_07705	COG1399	metal-binding, possibly nucleic acid-binding protein
HRJ37_07710	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HRJ37_07720	COG0454	-acetyltransferase
HRJ37_07725	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HRJ37_07730	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HRJ37_07735	COG2001	Belongs to the MraZ family
HRJ37_07740	COG0275	rRNA processing
HRJ37_07745	COG4839	cell division protein FtsL
HRJ37_07755	COG0768	penicillin binding
HRJ37_07760	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HRJ37_07765	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HRJ37_07770	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HRJ37_07775	COG0772	Belongs to the SEDS family
HRJ37_07780	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HRJ37_07785	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HRJ37_07790	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HRJ37_07795	COG3879	Bacterial protein of unknown function (DUF881)
HRJ37_07800	COG3879	Bacterial protein of unknown function (DUF881)
HRJ37_07805	COG3856	small basic protein
HRJ37_07810	COG0849	cell division
HRJ37_07815	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HRJ37_07820	COG4412	M6 family metalloprotease domain protein
HRJ37_07820	COG1404	Belongs to the peptidase S8 family
HRJ37_07830	COG1191	sigma factor activity
HRJ37_07835	COG1191	sigma factor activity
HRJ37_07840	COG2390	Transcriptional regulator
HRJ37_07855	COG3730	PTS system glucitol sorbitol-specific
HRJ37_07860	COG3732	PTS system glucitol sorbitol-specific
HRJ37_07870	COG1119	ATPase activity
HRJ37_07875	COG1873	PFAM PRC-barrel domain
HRJ37_07885	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HRJ37_07890	COG1799	cell septum assembly
HRJ37_07895	COG0762	integral membrane protein
HRJ37_07900	COG2302	S4 RNA-binding domain
HRJ37_07905	COG3599	regulation of cell shape
HRJ37_07910	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HRJ37_07915	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HRJ37_07920	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HRJ37_07925	COG0564	pseudouridine synthase activity
HRJ37_07930	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HRJ37_07935	COG2233	PERMEase
HRJ37_07940	COG0540	Belongs to the ATCase OTCase family
HRJ37_07945	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HRJ37_07950	COG0505	Belongs to the CarA family
HRJ37_07955	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HRJ37_07960	COG0543	2 iron, 2 sulfur cluster binding
HRJ37_07965	COG0167	dihydroorotate dehydrogenase activity
HRJ37_07970	COG0284	orotidine-5'-phosphate decarboxylase activity
HRJ37_07975	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HRJ37_07985	COG0175	sulfate reduction
HRJ37_07990	COG0306	phosphate transporter
HRJ37_07995	COG2046	Belongs to the sulfate adenylyltransferase family
HRJ37_08000	COG0529	Catalyzes the synthesis of activated sulfate
HRJ37_08005	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HRJ37_08010	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
HRJ37_08015	COG1648	precorrin-2 dehydrogenase activity
HRJ37_08025	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HRJ37_08030	COG1561	YicC-like family, N-terminal region
HRJ37_08035	COG2052	Domain of unknown function (DUF370)
HRJ37_08040	COG0194	GDP metabolic process
HRJ37_08045	COG1758	RNA polymerase activity
HRJ37_08050	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HRJ37_08055	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HRJ37_08060	COG0242	peptide deformylase activity
HRJ37_08065	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HRJ37_08070	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HRJ37_08070	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HRJ37_08075	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HRJ37_08080	COG0631	protein serine/threonine phosphatase activity
HRJ37_08085	COG0515	serine threonine protein kinase
HRJ37_08085	COG2815	serine threonine protein kinase
HRJ37_08090	COG1162	GTPase activity
HRJ37_08095	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HRJ37_08100	COG1564	THIamine pyrophosphokinase
HRJ37_08110	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HRJ37_08115	COG1302	Protein conserved in bacteria
HRJ37_08120	COG1461	Dihydroxyacetone kinase
HRJ37_08125	COG1760	l-serine dehydratase
HRJ37_08130	COG1760	l-serine dehydratase
HRJ37_08135	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HRJ37_08140	COG1349	DNA-binding transcription factor activity
HRJ37_08145	COG0416	fatty acid biosynthetic process
HRJ37_08150	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HRJ37_08155	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ37_08160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HRJ37_08170	COG1196	nuclear chromosome segregation
HRJ37_08175	COG0552	protein localization to endoplasmic reticulum
HRJ37_08180	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HRJ37_08185	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HRJ37_08190	COG0228	four-way junction DNA binding
HRJ37_08195	COG1837	Belongs to the UPF0109 family
HRJ37_08205	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HRJ37_08210	COG0336	Belongs to the RNA methyltransferase TrmD family
HRJ37_08215	COG0335	large ribosomal subunit rRNA binding
HRJ37_08220	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HRJ37_08225	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HRJ37_08235	COG2257	FlhB HrpN YscU SpaS Family
HRJ37_08240	COG0045	succinate-CoA ligase (ADP-forming) activity
HRJ37_08245	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HRJ37_08250	COG0758	DNA mediated transformation
HRJ37_08255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HRJ37_08260	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HRJ37_08265	COG4974	Belongs to the 'phage' integrase family
HRJ37_08270	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HRJ37_08275	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HRJ37_08280	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HRJ37_08285	COG1815	bacterial-type flagellum-dependent cell motility
HRJ37_08290	COG1558	bacterial-type flagellum-dependent cell motility
HRJ37_08295	COG1677	Flagellar hook-basal body complex protein FliE
HRJ37_08300	COG1766	The M ring may be actively involved in energy transduction
HRJ37_08305	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HRJ37_08310	COG1317	bacterial-type flagellum organization
HRJ37_08315	COG1157	protein secretion by the type III secretion system
HRJ37_08320	COG2882	bacterial-type flagellum organization
HRJ37_08325	COG3334	PFAM MgtE intracellular
HRJ37_08330	COG3144	bacterial-type flagellum assembly
HRJ37_08335	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HRJ37_08340	COG4786	Flagellar basal body rod
HRJ37_08345	COG1582	Flagellar protein (FlbD)
HRJ37_08350	COG1580	Controls the rotational direction of flagella during chemotaxis
HRJ37_08355	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HRJ37_08360	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HRJ37_08360	COG1776	CheC inhibitor of MCP methylation
HRJ37_08365	COG2201	protein-glutamate methylesterase activity
HRJ37_08370	COG3190	flagellar
HRJ37_08375	COG1338	Plays a role in the flagellum-specific transport system
HRJ37_08380	COG1987	bacterial-type flagellum assembly
HRJ37_08385	COG1684	flagellar biosynthetic protein fliR
HRJ37_08390	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HRJ37_08395	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HRJ37_08400	COG1419	protein localization to endoplasmic reticulum
HRJ37_08405	COG0455	bacterial-type flagellum organization
HRJ37_08410	COG2201	protein-glutamate methylesterase activity
HRJ37_08415	COG0643	Histidine kinase
HRJ37_08415	COG2198	Histidine kinase
HRJ37_08420	COG0835	chemotaxis
HRJ37_08425	COG1776	CheC inhibitor of MCP methylation
HRJ37_08435	COG1191	sigma factor activity
HRJ37_08450	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HRJ37_08455	COG0528	UMP kinase activity
HRJ37_08460	COG0233	cytoplasmic translational termination
HRJ37_08465	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HRJ37_08470	COG4589	Belongs to the CDS family
HRJ37_08475	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HRJ37_08480	COG0750	zinc metalloprotease
HRJ37_08485	COG0442	prolyl-tRNA aminoacylation
HRJ37_08490	COG2176	DNA-directed DNA polymerase activity
HRJ37_08505	COG3693	PFAM glycoside hydrolase, family 10
HRJ37_08515	COG0779	Required for maturation of 30S ribosomal subunits
HRJ37_08520	COG0195	Participates in both transcription termination and antitermination
HRJ37_08525	COG2740	Nucleic-acid-binding protein implicated in transcription termination
HRJ37_08530	COG1358	cellular component organization or biogenesis
HRJ37_08535	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HRJ37_08540	COG1550	Protein conserved in bacteria
HRJ37_08545	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HRJ37_08550	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HRJ37_08555	COG0196	riboflavin kinase activity
HRJ37_08560	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HRJ37_08565	COG1185	polyribonucleotide nucleotidyltransferase activity
HRJ37_08570	COG0726	polysaccharide deacetylase
HRJ37_08575	COG0612	Peptidase, M16
HRJ37_08580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HRJ37_08590	COG1132	(ABC) transporter
HRJ37_08595	COG1132	(ABC) transporter
HRJ37_08630	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
HRJ37_08650	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ37_08655	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ37_08660	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HRJ37_08665	COG1260	myo-inositol-1-phosphate synthase
HRJ37_08710	COG0367	asparagine synthase
HRJ37_08715	COG1873	PFAM PRC-barrel domain
HRJ37_08720	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HRJ37_08725	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HRJ37_08730	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HRJ37_08735	COG0527	aspartate kinase activity
HRJ37_08745	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HRJ37_08750	COG0740	serine-type endopeptidase activity
HRJ37_08760	COG1674	ftsk spoiiie
HRJ37_08760	COG4980	gas vesicle protein
HRJ37_08765	COG2188	Transcriptional regulator
HRJ37_08770	COG2814	Major facilitator Superfamily
HRJ37_08775	COG1033	growth of symbiont in host cell
HRJ37_08775	COG2409	Drug exporters of the RND superfamily
HRJ37_08780	COG0612	Peptidase, M16
HRJ37_08785	COG0612	Peptidase, M16
HRJ37_08795	COG2409	Drug exporters of the RND superfamily
HRJ37_08795	COG1033	growth of symbiont in host cell
HRJ37_08800	COG0300	oxidoreductase activity
HRJ37_08815	COG1426	Protein conserved in bacteria
HRJ37_08820	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HRJ37_08825	COG1058	Belongs to the CinA family
HRJ37_08825	COG1546	Belongs to the CinA family
HRJ37_08830	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HRJ37_08835	COG1418	mRNA catabolic process
HRJ37_08840	COG1692	metallophosphoesterase
HRJ37_08845	COG2359	stage V sporulation protein S
HRJ37_08850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HRJ37_08855	COG1063	alcohol dehydrogenase
HRJ37_08860	COG0156	8-amino-7-oxononanoate synthase activity
HRJ37_08865	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HRJ37_08870	COG4550	Control of competence regulator ComK, YlbF/YmcA
HRJ37_08880	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HRJ37_08885	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HRJ37_08905	COG1329	Transcriptional regulator
HRJ37_08910	COG4195	phage-related replication protein
HRJ37_08915	COG0457	Tetratricopeptide repeat
HRJ37_08920	COG1404	Belongs to the peptidase S8 family
HRJ37_08925	COG4195	phage-related replication protein
HRJ37_08930	COG1764	response to oxidative stress
HRJ37_08935	COG2076	Multidrug Resistance protein
HRJ37_08960	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HRJ37_08965	COG1923	regulation of RNA biosynthetic process
HRJ37_08980	COG1780	Probably involved in ribonucleotide reductase function
HRJ37_08985	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HRJ37_08990	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HRJ37_08995	COG4112	unkown
HRJ37_09005	COG0464	growth
HRJ37_09010	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HRJ37_09015	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
HRJ37_09020	COG0789	Transcriptional regulator
HRJ37_09025	COG0174	glutamine synthetase
HRJ37_09035	COG5444	nuclease activity
HRJ37_09075	COG0494	nUDIX hydrolase
HRJ37_09105	COG0457	Tetratricopeptide repeat
HRJ37_09120	COG5444	nuclease activity
HRJ37_09145	COG5646	InterPro IPR014922
HRJ37_09165	COG0457	Tetratricopeptide repeat
HRJ37_09175	COG3619	membrane
HRJ37_09180	COG3285	dna ligase
HRJ37_09180	COG1793	dna ligase
HRJ37_09185	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HRJ37_09190	COG4876	unkown
HRJ37_09200	COG1959	2 iron, 2 sulfur cluster binding
HRJ37_09205	COG0702	epimerase
HRJ37_09235	COG4555	ABC transporter
HRJ37_09240	COG0247	lactate metabolic process
HRJ37_09245	COG1139	Iron-sulfur cluster binding protein
HRJ37_09250	COG1556	Lactate utilization protein
HRJ37_09270	COG2323	membrane
HRJ37_09275	COG1309	transcriptional regulator
HRJ37_09280	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HRJ37_09280	COG2124	cytochrome p450
HRJ37_09285	COG3591	Belongs to the peptidase S1B family
HRJ37_09290	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HRJ37_09295	COG3209	COG3209 Rhs family protein
HRJ37_09300	COG1366	Belongs to the anti-sigma-factor antagonist family
HRJ37_09315	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HRJ37_09320	COG1388	LysM domain
HRJ37_09325	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HRJ37_09330	COG4224	UPF0291 protein
HRJ37_09335	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HRJ37_09345	COG3763	UPF0154 protein
HRJ37_09355	COG0785	Cytochrome C biogenesis protein
HRJ37_09360	COG4846	Membrane protein involved in cytochrome C biogenesis
HRJ37_09370	COG0071	Belongs to the small heat shock protein (HSP20) family
HRJ37_09385	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HRJ37_09390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HRJ37_09410	COG0824	Thioesterase
HRJ37_09420	COG4841	protein insertion into membrane
HRJ37_09425	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HRJ37_09430	COG1832	CoA-binding protein
HRJ37_09435	COG0187	DNA topoisomerase II activity
HRJ37_09440	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HRJ37_09450	COG0738	Major facilitator superfamily
HRJ37_09455	COG0473	3-isopropylmalate dehydrogenase activity
HRJ37_09460	COG0110	maltose O-acetyltransferase activity
HRJ37_09465	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HRJ37_09470	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HRJ37_09475	COG0640	Transcriptional regulator
HRJ37_09485	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HRJ37_09490	COG0251	oxidation-reduction process
HRJ37_09570	COG2205	protein histidine kinase activity
HRJ37_09575	COG0745	RESPONSE REGULATOR receiver
HRJ37_09585	COG3507	Belongs to the glycosyl hydrolase 43 family
HRJ37_09590	COG1012	belongs to the aldehyde dehydrogenase family
HRJ37_09595	COG1486	melibiose metabolic process
HRJ37_09600	COG0395	ABC-type sugar transport system, permease component
HRJ37_09605	COG1175	transmembrane transport
HRJ37_09610	COG1653	transport
HRJ37_09615	COG1609	Transcriptional regulator
HRJ37_09620	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HRJ37_09635	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HRJ37_09640	COG0456	acetyltransferase
HRJ37_09645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HRJ37_09660	COG5444	nuclease activity
HRJ37_09665	COG1846	Transcriptional regulator
HRJ37_09670	COG2814	Major facilitator Superfamily
HRJ37_09680	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HRJ37_09680	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HRJ37_09680	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HRJ37_09685	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HRJ37_09685	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HRJ37_09685	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HRJ37_09690	COG1105	Belongs to the carbohydrate kinase PfkB family
HRJ37_09700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HRJ37_09725	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HRJ37_09730	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HRJ37_09735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HRJ37_09740	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HRJ37_09745	COG1024	Enoyl-CoA hydratase
HRJ37_09750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HRJ37_09755	COG0511	ligase activity, forming carbon-carbon bonds
HRJ37_09760	COG0439	Biotin carboxylase
HRJ37_09765	COG0318	PFAM AMP-dependent synthetase and ligase
HRJ37_09770	COG1960	acyl-CoA dehydrogenase activity
HRJ37_09775	COG1649	PFAM Uncharacterised BCR, COG1649
HRJ37_09785	COG1349	DNA-binding transcription factor activity
HRJ37_09790	COG1942	4-Oxalocrotonate Tautomerase
HRJ37_09800	COG3835	regulator
HRJ37_09805	COG0277	FAD linked oxidase domain protein
HRJ37_09810	COG0247	lactate metabolic process
HRJ37_09830	COG0166	Belongs to the GPI family
HRJ37_09835	COG2246	polysaccharide biosynthetic process
HRJ37_09840	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HRJ37_09845	COG0586	Pfam SNARE associated Golgi protein
HRJ37_09850	COG1587	Uroporphyrinogen-III synthase
HRJ37_09865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HRJ37_09885	COG0534	Mate efflux family protein
HRJ37_09890	COG2027	D-alanyl-D-alanine carboxypeptidase
HRJ37_09895	COG4677	pectinesterase activity
HRJ37_09900	COG2323	membrane
HRJ37_09905	COG2146	nitrite reductase [NAD(P)H] activity
HRJ37_09910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HRJ37_09915	COG0243	molybdopterin cofactor binding
HRJ37_09920	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HRJ37_09925	COG2223	nitrite transmembrane transporter activity
HRJ37_09930	COG0493	'glutamate synthase
HRJ37_09935	COG0069	glutamate synthase activity
HRJ37_09935	COG0070	glutamate synthase
HRJ37_09935	COG0067	glutamate synthase
HRJ37_09940	COG0583	DNA-binding transcription factor activity
HRJ37_09950	COG1132	(ABC) transporter
HRJ37_09955	COG0789	Transcriptional regulator
HRJ37_09955	COG4978	Transcriptional regulator
HRJ37_09960	COG0454	-acetyltransferase
HRJ37_09965	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HRJ37_09970	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HRJ37_09975	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HRJ37_09985	COG0243	molybdopterin cofactor binding
HRJ37_09995	COG1070	Carbohydrate kinase
HRJ37_10000	COG2115	Belongs to the xylose isomerase family
HRJ37_10005	COG1940	carbohydrate kinase activity
HRJ37_10015	COG2211	Major facilitator Superfamily
HRJ37_10020	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HRJ37_10025	COG1994	Peptidase M50
HRJ37_10045	COG1309	transcriptional regulator
HRJ37_10050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HRJ37_10070	COG0640	Transcriptional regulator
HRJ37_10075	COG0531	amino acid
HRJ37_10080	COG0741	lytic transglycosylase activity
HRJ37_10085	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HRJ37_10090	COG2079	MmgE PrpD family protein
HRJ37_10095	COG0372	Belongs to the citrate synthase family
HRJ37_10100	COG2322	membrane
HRJ37_10110	COG3584	3D domain protein
HRJ37_10110	COG1388	LysM domain
HRJ37_10115	COG0514	ATP-dependent DNA helicase (RecQ)
HRJ37_10125	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HRJ37_10150	COG1012	belongs to the aldehyde dehydrogenase family
HRJ37_10155	COG1657	PFAM Prenyltransferase squalene oxidase
HRJ37_10160	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HRJ37_10165	COG0385	Bile acid
HRJ37_10170	COG0508	dehydrogenase complex catalyzes the overall conversion of
HRJ37_10175	COG0567	Dehydrogenase, E1 component
HRJ37_10180	COG4548	von Willebrand factor, type A
HRJ37_10185	COG0714	Associated with various cellular activities
HRJ37_10190	COG2032	superoxide dismutase activity
HRJ37_10195	COG0791	NLP P60 protein
HRJ37_10195	COG1388	LysM domain
HRJ37_10200	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HRJ37_10205	COG0534	Mate efflux family protein
HRJ37_10210	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HRJ37_10215	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HRJ37_10225	COG2962	Rard protein
HRJ37_10240	COG1733	regulation of RNA biosynthetic process
HRJ37_10245	COG0778	Nitroreductase
HRJ37_10255	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HRJ37_10260	COG3409	Peptidoglycan-binding domain 1 protein
HRJ37_10260	COG0793	Belongs to the peptidase S41A family
HRJ37_10265	COG2226	methyltransferase
HRJ37_10275	COG1876	peptidase activity
HRJ37_10280	COG0813	purine-nucleoside phosphorylase activity
HRJ37_10290	COG0671	phosphoesterase, PA-phosphatase related
HRJ37_10305	COG4479	Belongs to the UPF0346 family
HRJ37_10315	COG1509	lysine 2,3-aminomutase activity
HRJ37_10320	COG3829	transcription factor binding
HRJ37_10325	COG0463	Glycosyl transferase, family 2
HRJ37_10340	COG4641	Protein conserved in bacteria
HRJ37_10350	COG1086	Polysaccharide biosynthesis protein
HRJ37_10355	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HRJ37_10360	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HRJ37_10365	COG1846	Transcriptional regulator
HRJ37_10385	COG4698	Protein conserved in bacteria
HRJ37_10390	COG2755	lipolytic protein G-D-S-L family
HRJ37_10395	COG1999	signal sequence binding
HRJ37_10410	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HRJ37_10415	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HRJ37_10420	COG1272	protein, Hemolysin III
HRJ37_10425	COG0204	Acyl-transferase
HRJ37_10430	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HRJ37_10435	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HRJ37_10440	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HRJ37_10450	COG2521	methyltransferase
HRJ37_10450	COG2136	Putative SAM-dependent methyltransferase
HRJ37_10460	COG0129	dihydroxy-acid dehydratase activity
HRJ37_10465	COG1413	lyase activity
HRJ37_10470	COG1418	mRNA catabolic process
HRJ37_10475	COG0386	Belongs to the glutathione peroxidase family
HRJ37_10480	COG2759	Belongs to the formate--tetrahydrofolate ligase family
HRJ37_10485	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
HRJ37_10490	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HRJ37_10500	COG1278	Cold shock
HRJ37_10515	COG0328	RNA-DNA hybrid ribonuclease activity
HRJ37_10520	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HRJ37_10525	COG0328	RNA-DNA hybrid ribonuclease activity
HRJ37_10535	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HRJ37_10545	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HRJ37_10555	COG1755	Isoprenylcysteine carboxyl methyltransferase
HRJ37_10560	COG3424	synthase
HRJ37_10565	COG0456	acetyltransferase
HRJ37_10565	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HRJ37_10570	COG0726	polysaccharide deacetylase
HRJ37_10575	COG2233	PERMEase
HRJ37_10580	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HRJ37_10585	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HRJ37_10590	COG1199	ATP-dependent helicase activity
HRJ37_10600	COG0116	Belongs to the methyltransferase superfamily
HRJ37_10610	COG3599	regulation of cell shape
HRJ37_10615	COG4474	Belongs to the UPF0398 family
HRJ37_10625	COG3359	exonuclease
HRJ37_10630	COG1205	dead DEAH box helicase
HRJ37_10630	COG1111	helicase
HRJ37_10635	COG1902	pentaerythritol trinitrate reductase activity
HRJ37_10640	COG2190	(PTS) system
HRJ37_10645	COG0071	Belongs to the small heat shock protein (HSP20) family
HRJ37_10675	COG3331	DNA recombination
HRJ37_10680	COG4499	WXG100 protein secretion system (Wss), protein YukC
HRJ37_10680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HRJ37_10690	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HRJ37_10695	COG3935	DnaD domain protein
HRJ37_10700	COG0017	Asparaginyl-tRNA synthetase
HRJ37_10705	COG5353	protein conserved in bacteria
HRJ37_10715	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HRJ37_10715	COG1199	ATP-dependent helicase activity
HRJ37_10720	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HRJ37_10725	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HRJ37_10730	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HRJ37_10740	COG0617	tRNA 3'-terminal CCA addition
HRJ37_10745	COG0438	transferase activity, transferring glycosyl groups
HRJ37_10750	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HRJ37_10755	COG1803	Methylglyoxal synthase
HRJ37_10760	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HRJ37_10765	COG1694	Mazg nucleotide pyrophosphohydrolase
HRJ37_10770	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HRJ37_10780	COG4347	Protein of unknown function (DUF1405)
HRJ37_10785	COG2010	Cytochrome c
HRJ37_10785	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HRJ37_10790	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HRJ37_10795	COG0723	plastoquinol--plastocyanin reductase activity
HRJ37_10805	COG5582	Belongs to the UPF0302 family
HRJ37_10810	COG0457	Tetratricopeptide repeat
HRJ37_10815	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HRJ37_10820	COG0287	Prephenate dehydrogenase
HRJ37_10825	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HRJ37_10830	COG0159	tryptophan synthase activity
HRJ37_10835	COG0133	tryptophan synthase activity
HRJ37_10845	COG0134	indole-3-glycerol-phosphate synthase activity
HRJ37_10850	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HRJ37_10860	COG4401	Chorismate mutase type I
HRJ37_10865	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HRJ37_10870	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HRJ37_10875	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HRJ37_10880	COG0105	UTP biosynthetic process
HRJ37_10885	COG0142	geranyltranstransferase activity
HRJ37_10890	COG2226	methyltransferase
HRJ37_10895	COG0142	geranyltranstransferase activity
HRJ37_10905	COG0302	gtp cyclohydrolase
HRJ37_10910	COG0776	regulation of translation
HRJ37_10915	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HRJ37_10930	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HRJ37_10935	COG1160	GTP binding
HRJ37_10960	COG1304	FMN binding
HRJ37_10965	COG0539	negative regulation of cytoplasmic translation
HRJ37_10970	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HRJ37_10980	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
HRJ37_10985	COG2959	enzyme of heme biosynthesis
HRJ37_10990	COG3773	Cell wall hydrolase
HRJ37_10990	COG3409	Peptidoglycan-binding domain 1 protein
HRJ37_10995	COG2339	peptidase activity
HRJ37_11000	COG0492	ferredoxin-NADP+ reductase activity
HRJ37_11005	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HRJ37_11010	COG4862	establishment of competence for transformation
HRJ37_11015	COG1408	metallophosphoesterase
HRJ37_11025	COG1388	LysM domain
HRJ37_11030	COG1266	CAAX protease self-immunity
HRJ37_11035	COG0514	ATP-dependent DNA helicase (RecQ)
HRJ37_11040	COG4955	Helix-turn-helix domain
HRJ37_11045	COG1141	Ferredoxin
HRJ37_11050	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HRJ37_11055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HRJ37_11070	COG1595	DNA-templated transcription, initiation
HRJ37_11075	COG5002	protein histidine kinase activity
HRJ37_11080	COG0745	RESPONSE REGULATOR receiver
HRJ37_11085	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HRJ37_11090	COG1333	cytochrome c biogenesis protein
HRJ37_11095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HRJ37_11100	COG1187	pseudouridine synthase activity
HRJ37_11105	COG0700	Nucleoside recognition
HRJ37_11110	COG2715	membrane protein required for spore maturation
HRJ37_11115	COG1686	Belongs to the peptidase S11 family
HRJ37_11125	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HRJ37_11130	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HRJ37_11140	COG1547	Domain of unknown function (DUF309)
HRJ37_11145	COG0456	acetyltransferase
HRJ37_11150	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HRJ37_11155	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HRJ37_11155	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HRJ37_11160	COG0307	riboflavin synthase, alpha
HRJ37_11180	COG2814	Major facilitator Superfamily
HRJ37_11185	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HRJ37_11190	COG4086	secreted protein
HRJ37_11195	COG0019	diaminopimelate decarboxylase activity
HRJ37_11200	COG0697	spore germination
HRJ37_11215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HRJ37_11235	COG1191	sigma factor activity
HRJ37_11240	COG2172	sigma factor antagonist activity
HRJ37_11250	COG1686	Belongs to the peptidase S11 family
HRJ37_11255	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HRJ37_11260	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HRJ37_11265	COG4974	Belongs to the 'phage' integrase family
HRJ37_11275	COG0735	belongs to the Fur family
HRJ37_11280	COG1300	Membrane
HRJ37_11285	COG1404	Belongs to the peptidase S8 family
HRJ37_11295	COG2153	protein acetylation
HRJ37_11300	COG1379	DNA repair
HRJ37_11305	COG0494	nUDIX hydrolase
HRJ37_11310	COG0667	Aldo Keto reductase
HRJ37_11325	COG1073	alpha beta
HRJ37_11330	COG0457	Tetratricopeptide repeat
HRJ37_11340	COG4918	Iron-sulphur cluster biosynthesis
HRJ37_11345	COG4305	rare lipoprotein A
HRJ37_11350	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HRJ37_11350	COG0456	acetyltransferase
HRJ37_11355	COG0456	acetyltransferase
HRJ37_11365	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HRJ37_11375	COG2211	Major facilitator Superfamily
HRJ37_11380	COG1072	(Pantothenic acid kinase))
HRJ37_11385	COG0446	pyridine nucleotide-disulphide oxidoreductase
HRJ37_11395	COG0300	oxidoreductase activity
HRJ37_11400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HRJ37_11405	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HRJ37_11425	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HRJ37_11430	COG4187	Peptidase family M20/M25/M40
HRJ37_11435	COG1902	pentaerythritol trinitrate reductase activity
HRJ37_11440	COG0596	Alpha beta hydrolase
HRJ37_11445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HRJ37_11455	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HRJ37_11460	COG2188	Transcriptional regulator
HRJ37_11465	COG2723	6-phospho-beta-galactosidase activity
HRJ37_11470	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HRJ37_11475	COG1447	Phosphotransferase system cellobiose-specific component IIA
HRJ37_11480	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HRJ37_11490	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ37_11500	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HRJ37_11505	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HRJ37_11515	COG0706	membrane insertase activity
HRJ37_11520	COG0835	chemotaxis
HRJ37_11525	COG2195	Cleaves the N-terminal amino acid of tripeptides
HRJ37_11530	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HRJ37_11535	COG0346	lactoylglutathione lyase activity
HRJ37_11545	COG1376	ErfK ybiS ycfS ynhG family protein
HRJ37_11550	COG4129	membrane
HRJ37_11555	COG1126	abc transporter atp-binding protein
HRJ37_11560	COG0765	amino acid transport
HRJ37_11565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HRJ37_11575	COG1597	lipid kinase activity
HRJ37_11585	COG0508	dehydrogenase complex catalyzes the overall conversion of
HRJ37_11590	COG0022	dehydrogenase e1 component
HRJ37_11595	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HRJ37_11600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HRJ37_11605	COG3426	butyrate kinase activity
HRJ37_11610	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HRJ37_11615	COG0280	phosphate acetyltransferase
HRJ37_11620	COG3290	protein histidine kinase activity
HRJ37_11620	COG3829	transcription factor binding
HRJ37_11630	COG0584	glycerophosphoryl diester phosphodiesterase
HRJ37_11635	COG0457	Tetratricopeptide repeat
HRJ37_11640	COG0745	RESPONSE REGULATOR receiver
HRJ37_11645	COG0750	zinc metalloprotease
HRJ37_11650	COG0497	DNA recombination
HRJ37_11655	COG1438	arginine binding
HRJ37_11660	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
HRJ37_11665	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HRJ37_11670	COG0142	geranyltranstransferase activity
HRJ37_11675	COG1722	exodeoxyribonuclease VII activity
HRJ37_11680	COG1570	exodeoxyribonuclease VII activity
HRJ37_11685	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HRJ37_11690	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HRJ37_11695	COG1302	Protein conserved in bacteria
HRJ37_11700	COG0439	Biotin carboxylase
HRJ37_11705	COG0511	ligase activity, forming carbon-carbon bonds
HRJ37_11745	COG3854	ATPases associated with a variety of cellular activities
HRJ37_11755	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HRJ37_11760	COG0006	proline dipeptidase activity
HRJ37_11765	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HRJ37_11775	COG3872	metal-dependent enzyme
HRJ37_11785	COG1752	Esterase of the alpha-beta hydrolase superfamily
HRJ37_11790	COG1321	iron dependent repressor
HRJ37_11795	COG0095	Lipoate-protein ligase
HRJ37_11800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HRJ37_11805	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HRJ37_11810	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HRJ37_11815	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HRJ37_11820	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HRJ37_11845	COG0681	Belongs to the peptidase S26 family
HRJ37_11880	COG4970	Tfp pilus assembly protein FimT
HRJ37_11885	COG4537	Required for transformation and DNA binding
HRJ37_11890	COG1459	type II secretion system
HRJ37_11895	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HRJ37_11900	COG1366	Belongs to the anti-sigma-factor antagonist family
HRJ37_11910	COG1393	Belongs to the ArsC family
HRJ37_11920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HRJ37_11930	COG0011	TIGRFAM Protein of
HRJ37_11935	COG2814	Major facilitator Superfamily
HRJ37_11940	COG2866	Carboxypeptidase
HRJ37_11945	COG1368	sulfuric ester hydrolase activity
HRJ37_11950	COG1940	carbohydrate kinase activity
HRJ37_11955	COG4483	Protein conserved in bacteria
HRJ37_11960	COG0705	Rhomboid family
HRJ37_11960	COG0457	Tetratricopeptide repeat
HRJ37_11975	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HRJ37_11980	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HRJ37_11990	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HRJ37_11995	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HRJ37_12000	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HRJ37_12005	COG0581	inorganic phosphate transmembrane transporter activity
HRJ37_12010	COG0573	inorganic phosphate transmembrane transporter activity
HRJ37_12015	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HRJ37_12025	COG0477	Major facilitator Superfamily
HRJ37_12030	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HRJ37_12035	COG2839	Protein conserved in bacteria
HRJ37_12040	COG5521	maltodextrose utilization protein MalA
HRJ37_12045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HRJ37_12050	COG1388	LysM domain
HRJ37_12055	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HRJ37_12060	COG4709	membrane
HRJ37_12065	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
HRJ37_12070	COG1940	carbohydrate kinase activity
HRJ37_12075	COG0735	belongs to the Fur family
HRJ37_12080	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HRJ37_12085	COG1121	(ABC) transporter
HRJ37_12090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HRJ37_12105	COG0513	Belongs to the DEAD box helicase family
HRJ37_12115	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HRJ37_12120	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HRJ37_12125	COG2384	SAM-dependent methyltransferase
HRJ37_12130	COG2010	Cytochrome c
HRJ37_12135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HRJ37_12140	COG0358	DNA primase activity
HRJ37_12145	COG1671	Belongs to the UPF0178 family
HRJ37_12150	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
HRJ37_12155	COG0517	IMP dehydrogenase activity
HRJ37_12160	COG0751	glycine-tRNA ligase activity
HRJ37_12165	COG0752	glycyl-tRNA synthetase alpha subunit
HRJ37_12170	COG1381	Involved in DNA repair and RecF pathway recombination
HRJ37_12180	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HRJ37_12185	COG0295	cytidine deaminase activity
HRJ37_12190	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HRJ37_12195	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HRJ37_12200	COG1480	7TM receptor with intracellular HD hydrolase
HRJ37_12205	COG1702	phosphate starvation-inducible protein PhoH
HRJ37_12210	COG0561	phosphatase activity
HRJ37_12225	COG4864	UPF0365 protein
HRJ37_12230	COG1030	water channel activity
HRJ37_12235	COG1610	YqeY-like protein
HRJ37_12245	COG1283	sodium-dependent phosphate transmembrane transporter activity
HRJ37_12250	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HRJ37_12255	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HRJ37_12260	COG2264	protein methyltransferase activity
HRJ37_12265	COG0484	heat shock protein binding
HRJ37_12270	COG0443	Heat shock 70 kDa protein
HRJ37_12275	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HRJ37_12280	COG1420	regulation of RNA biosynthetic process
HRJ37_12285	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HRJ37_12290	COG0481	GTPase activity
HRJ37_12300	COG0860	N-Acetylmuramoyl-L-alanine amidase
HRJ37_12305	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HRJ37_12310	COG0268	Binds directly to 16S ribosomal RNA
HRJ37_12315	COG1466	dna polymerase III delta subunit
HRJ37_12325	COG2333	competence protein COMEC
HRJ37_12325	COG0658	competence protein
HRJ37_12330	COG2131	deaminase
HRJ37_12335	COG1596	polysaccharide export
HRJ37_12335	COG1555	photosystem II stabilization
HRJ37_12340	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HRJ37_12345	COG2226	methyltransferase
HRJ37_12350	COG0799	negative regulation of ribosome biogenesis
HRJ37_12355	COG1713	HD superfamily hydrolase involved in NAD metabolism
HRJ37_12360	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HRJ37_12365	COG1534	Rna-binding protein
HRJ37_12370	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HRJ37_12375	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HRJ37_12380	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
HRJ37_12395	COG2755	lipolytic protein G-D-S-L family
HRJ37_12405	COG0457	Tetratricopeptide repeat
HRJ37_12430	COG0726	polysaccharide deacetylase
HRJ37_12465	COG1131	(ABC) transporter
HRJ37_12490	COG2160	L-arabinose isomerase activity
HRJ37_12505	COG1609	Transcriptional regulator
HRJ37_12515	COG1846	Transcriptional regulator
HRJ37_12525	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HRJ37_12530	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HRJ37_12535	COG1733	regulation of RNA biosynthetic process
HRJ37_12595	COG1309	transcriptional regulator
HRJ37_12600	COG0109	protoheme IX farnesyltransferase activity
HRJ37_12605	COG2602	Beta-lactamase
HRJ37_12610	COG1960	acyl-CoA dehydrogenase activity
HRJ37_12615	COG1126	abc transporter atp-binding protein
HRJ37_12620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HRJ37_12625	COG0765	amino acid transport
HRJ37_12635	COG3546	catalase activity
HRJ37_12640	COG1063	alcohol dehydrogenase
HRJ37_12650	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ37_12660	COG1115	amino acid carrier protein
HRJ37_12665	COG0583	DNA-binding transcription factor activity
HRJ37_12670	COG1063	alcohol dehydrogenase
HRJ37_12675	COG2226	methyltransferase
HRJ37_12700	COG0626	cystathionine gamma-synthase activity
HRJ37_12705	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HRJ37_12710	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HRJ37_12715	COG2226	methyltransferase
HRJ37_12730	COG0768	penicillin binding
HRJ37_12735	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HRJ37_12740	COG0572	uridine kinase
HRJ37_12755	COG4122	O-methyltransferase activity
HRJ37_12760	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HRJ37_12765	COG0183	Belongs to the thiolase family
HRJ37_12770	COG0318	PFAM AMP-dependent synthetase and ligase
HRJ37_12775	COG1268	BioY protein
HRJ37_12780	COG3906	Belongs to the UPF0473 family
HRJ37_12785	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HRJ37_12790	COG4472	Bacterial protein of unknown function (DUF965)
HRJ37_12795	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HRJ37_12800	COG0628	permease
HRJ37_12805	COG1126	abc transporter atp-binding protein
HRJ37_12810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HRJ37_12815	COG0765	amino acid transport
HRJ37_12820	COG0765	amino acid transport
HRJ37_12835	COG3881	PFAM PRC-barrel domain
HRJ37_12840	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HRJ37_12845	COG0457	Tetratricopeptide repeat
HRJ37_12850	COG0482	sulfurtransferase activity
HRJ37_12855	COG1104	cysteine desulfurase activity
HRJ37_12860	COG1959	2 iron, 2 sulfur cluster binding
HRJ37_12865	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HRJ37_12870	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HRJ37_12885	COG0124	histidyl-tRNA synthetase
HRJ37_12895	COG4991	sh3 domain protein
HRJ37_12895	COG3103	Sh3 type 3 domain protein
HRJ37_12895	COG0860	N-Acetylmuramoyl-L-alanine amidase
HRJ37_12900	COG1490	D-aminoacyl-tRNA deacylase activity
HRJ37_12905	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HRJ37_12910	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HRJ37_12915	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HRJ37_12915	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HRJ37_12920	COG5416	Lipopolysaccharide assembly protein A domain
HRJ37_12925	COG0490	domain, Protein
HRJ37_12930	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HRJ37_12930	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HRJ37_12940	COG2244	polysaccharide biosynthetic process
HRJ37_12945	COG2323	membrane
HRJ37_12955	COG1862	Preprotein translocase
HRJ37_12960	COG0343	queuine tRNA-ribosyltransferase activity
HRJ37_12965	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HRJ37_12975	COG2255	four-way junction helicase activity
HRJ37_12980	COG0632	four-way junction helicase activity
HRJ37_12990	COG2112	serine threonine protein kinase
HRJ37_13005	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HRJ37_13020	COG1388	LysM domain
HRJ37_13025	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HRJ37_13030	COG0157	Belongs to the NadC ModD family
HRJ37_13035	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HRJ37_13040	COG1104	cysteine desulfurase activity
HRJ37_13045	COG1827	regulation of RNA biosynthetic process
HRJ37_13050	COG0077	Prephenate dehydratase
HRJ37_13055	COG4492	Belongs to the UPF0735 family
HRJ37_13060	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HRJ37_13065	COG3290	protein histidine kinase activity
HRJ37_13070	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HRJ37_13075	COG2868	ribosomal protein
HRJ37_13080	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HRJ37_13085	COG1994	Peptidase M50
HRJ37_13090	COG0739	heme binding
HRJ37_13095	COG2894	cell division
HRJ37_13100	COG0850	regulation of cytokinetic process
HRJ37_13105	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HRJ37_13115	COG1077	Cell shape determining protein MreB Mrl
HRJ37_13120	COG2003	Belongs to the UPF0758 family
HRJ37_13125	COG0424	maF-like protein
HRJ37_13135	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HRJ37_13140	COG0285	dihydrofolate synthase activity
HRJ37_13145	COG0525	valine-tRNA ligase activity
HRJ37_13155	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HRJ37_13160	COG1388	LysM domain
HRJ37_13165	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HRJ37_13170	COG0113	porphobilinogen synthase activity
HRJ37_13175	COG1587	Uroporphyrinogen-III synthase
HRJ37_13180	COG0181	hydroxymethylbilane synthase activity
HRJ37_13185	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HRJ37_13190	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HRJ37_13215	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HRJ37_13220	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HRJ37_13225	COG0470	DNA polymerase III
HRJ37_13225	COG1067	ATP-dependent peptidase activity
HRJ37_13230	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HRJ37_13235	COG0544	peptidyl-prolyl cis-trans isomerase activity
HRJ37_13240	COG1477	protein flavinylation
HRJ37_13240	COG0457	Tetratricopeptide repeat
HRJ37_13245	COG0066	3-isopropylmalate dehydratase activity
HRJ37_13250	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HRJ37_13255	COG0473	3-isopropylmalate dehydrogenase activity
HRJ37_13260	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HRJ37_13265	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HRJ37_13270	COG0440	acetolactate synthase activity
HRJ37_13275	COG0028	Belongs to the TPP enzyme family
HRJ37_13280	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HRJ37_13285	COG2706	6-phosphogluconolactonase activity
HRJ37_13290	COG3339	Conserved Protein
HRJ37_13295	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HRJ37_13300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HRJ37_13305	COG1696	Membrane protein involved in D-alanine export
HRJ37_13310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HRJ37_13350	COG0622	Phosphoesterase
HRJ37_13355	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HRJ37_13360	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HRJ37_13365	COG5401	PFAM Sporulation and spore germination
HRJ37_13370	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HRJ37_13375	COG1846	Transcriptional regulator
HRJ37_13380	COG2197	response regulator
HRJ37_13385	COG2851	Citrate transporter
HRJ37_13390	COG0583	DNA-binding transcription factor activity
HRJ37_13395	COG2828	Protein conserved in bacteria
HRJ37_13405	COG0824	Thioesterase
HRJ37_13410	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HRJ37_13415	COG1053	succinate dehydrogenase
HRJ37_13420	COG2009	succinate dehydrogenase
HRJ37_13425	COG1719	4-vinyl reductase, 4VR
HRJ37_13430	COG0527	aspartate kinase activity
HRJ37_13435	COG0322	excinuclease ABC activity
HRJ37_13440	COG3118	belongs to the thioredoxin family
HRJ37_13445	COG3534	alpha-L-arabinofuranosidase
HRJ37_13450	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HRJ37_13455	COG2086	electron transfer activity
HRJ37_13460	COG1024	Enoyl-CoA hydratase
HRJ37_13465	COG1309	transcriptional regulator
HRJ37_13470	COG0318	PFAM AMP-dependent synthetase and ligase
HRJ37_13480	COG3766	membrane
HRJ37_13485	COG1193	negative regulation of DNA recombination
HRJ37_13490	COG1796	DNA polymerase
HRJ37_13490	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HRJ37_13495	COG1286	toxin biosynthetic process
HRJ37_13500	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HRJ37_13505	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HRJ37_13510	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HRJ37_13510	COG0072	phenylalanine-tRNA ligase activity
HRJ37_13515	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HRJ37_13520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HRJ37_13530	COG1966	Carbon starvation protein
HRJ37_13535	COG1363	Peptidase, m42
HRJ37_13545	COG3326	Membrane
HRJ37_13550	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HRJ37_13555	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HRJ37_13560	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HRJ37_13565	COG1346	cytolysis
HRJ37_13575	COG3279	Response regulator of the LytR AlgR family
HRJ37_13580	COG3275	phosphorelay sensor kinase activity
HRJ37_13585	COG1011	Hydrolase
HRJ37_13595	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HRJ37_13605	COG0398	Pfam SNARE associated Golgi protein
HRJ37_13610	COG1484	DNA-dependent DNA replication
HRJ37_13615	COG3611	Membrane attachment protein
HRJ37_13620	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HRJ37_13630	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HRJ37_13635	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HRJ37_13640	COG0237	dephospho-CoA kinase activity
HRJ37_13645	COG1971	Probably functions as a manganese efflux pump
HRJ37_13650	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HRJ37_13655	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HRJ37_13655	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HRJ37_13660	COG5002	protein histidine kinase activity
HRJ37_13665	COG0745	RESPONSE REGULATOR receiver
HRJ37_13670	COG0039	L-malate dehydrogenase activity
HRJ37_13675	COG0538	isocitrate dehydrogenase activity
HRJ37_13680	COG0372	Belongs to the citrate synthase family
HRJ37_13685	COG2707	UPF0756 membrane protein
HRJ37_13690	COG0628	permease
HRJ37_13695	COG3030	protein affecting phage T7 exclusion by the F plasmid
HRJ37_13705	COG0205	6-phosphofructokinase activity
HRJ37_13710	COG0825	malonyl-CoA metabolic process
HRJ37_13715	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HRJ37_13720	COG0281	malic enzyme
HRJ37_13725	COG0587	DNA-directed DNA polymerase activity
HRJ37_13745	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HRJ37_13755	COG4109	DRTGG domain
HRJ37_13760	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HRJ37_13765	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ37_13775	COG0165	Argininosuccinate lyase
HRJ37_13780	COG0137	argininosuccinate synthase activity
HRJ37_13785	COG0521	Mo-molybdopterin cofactor biosynthetic process
HRJ37_13790	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HRJ37_13795	COG0827	DNA restriction-modification system
HRJ37_13800	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HRJ37_13805	COG3874	Sporulation protein YtfJ
HRJ37_13815	COG1714	RDD family
HRJ37_13820	COG0616	signal peptide processing
HRJ37_13825	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HRJ37_13835	COG3239	Fatty acid desaturase
HRJ37_13840	COG4585	Histidine kinase
HRJ37_13845	COG2197	response regulator
HRJ37_13850	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HRJ37_13855	COG0745	RESPONSE REGULATOR receiver
HRJ37_13860	COG2205	protein histidine kinase activity
HRJ37_13865	COG0772	Belongs to the SEDS family
HRJ37_13870	COG1695	Transcriptional regulator
HRJ37_13875	COG1136	(ABC) transporter
HRJ37_13880	COG0577	efflux transmembrane transporter activity
HRJ37_13885	COG0402	S-adenosylhomocysteine deaminase activity
HRJ37_13890	COG2249	NAD(P)H dehydrogenase (quinone) activity
HRJ37_13910	COG1279	arginine transmembrane transporter activity
HRJ37_13930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HRJ37_13940	COG0301	tRNA thio-modification
HRJ37_13945	COG1104	cysteine desulfurase activity
HRJ37_13950	COG1114	Component of the transport system for branched-chain amino acids
HRJ37_13955	COG1114	Component of the transport system for branched-chain amino acids
HRJ37_13960	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HRJ37_13965	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HRJ37_13970	COG1309	transcriptional regulator
HRJ37_13975	COG1956	GAF domain-containing protein
HRJ37_13980	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HRJ37_13990	COG1335	isochorismatase
HRJ37_14000	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HRJ37_14005	COG2329	Antibiotic biosynthesis monooxygenase
HRJ37_14010	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HRJ37_14015	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HRJ37_14020	COG0454	-acetyltransferase
HRJ37_14025	COG0517	IMP dehydrogenase activity
HRJ37_14030	COG0123	including yeast histone deacetylase and acetoin utilization protein
HRJ37_14035	COG1609	Transcriptional regulator
HRJ37_14040	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HRJ37_14040	COG1605	Chorismate mutase
HRJ37_14045	COG3118	belongs to the thioredoxin family
HRJ37_14050	COG4980	gas vesicle protein
HRJ37_14055	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HRJ37_14060	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HRJ37_14065	COG1674	ftsk spoiiie
HRJ37_14070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HRJ37_14075	COG4848	Belongs to the UPF0354 family
HRJ37_14080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HRJ37_14095	COG1363	Peptidase, m42
HRJ37_14100	COG5584	Small secreted protein
HRJ37_14110	COG0281	malic enzyme
HRJ37_14115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HRJ37_14120	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HRJ37_14130	COG0510	thiamine kinase activity
HRJ37_14135	COG1597	lipid kinase activity
HRJ37_14145	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HRJ37_14150	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HRJ37_14155	COG3340	Belongs to the peptidase S51 family
HRJ37_14160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HRJ37_14165	COG2252	PERMEase
HRJ37_14170	COG1349	DNA-binding transcription factor activity
HRJ37_14175	COG1187	pseudouridine synthase activity
HRJ37_14180	COG2244	polysaccharide biosynthetic process
HRJ37_14185	COG2081	HI0933 family
HRJ37_14195	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HRJ37_14200	COG3196	Protein conserved in bacteria
HRJ37_14210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HRJ37_14215	COG5578	integral membrane protein
HRJ37_14220	COG0673	inositol 2-dehydrogenase activity
HRJ37_14225	COG1653	transport
HRJ37_14230	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HRJ37_14235	COG4209	transmembrane transport
HRJ37_14240	COG2207	Transcriptional regulator
HRJ37_14245	COG1733	regulation of RNA biosynthetic process
HRJ37_14250	COG2814	Major facilitator Superfamily
HRJ37_14255	COG0656	L-ascorbic acid biosynthetic process
HRJ37_14260	COG1653	transport
HRJ37_14265	COG0395	ABC-type sugar transport system, permease component
HRJ37_14270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HRJ37_14275	COG1073	alpha beta
HRJ37_14280	COG0495	leucyl-tRNA aminoacylation
HRJ37_14290	COG1366	Belongs to the anti-sigma-factor antagonist family
HRJ37_14290	COG2202	Pas domain
HRJ37_14295	COG2433	Pfam Transposase IS66
HRJ37_14300	COG0577	efflux transmembrane transporter activity
HRJ37_14305	COG1136	(ABC) transporter
HRJ37_14315	COG1131	(ABC) transporter
HRJ37_14320	COG1725	Transcriptional regulator
HRJ37_14340	COG1242	4 iron, 4 sulfur cluster binding
HRJ37_14345	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HRJ37_14350	COG4326	sporulation control protein
HRJ37_14360	COG2267	carboxylic ester hydrolase activity
HRJ37_14365	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HRJ37_14370	COG0367	asparagine synthase
HRJ37_14375	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HRJ37_14380	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HRJ37_14390	COG1506	peptidase
HRJ37_14395	COG1233	COG1233 Phytoene dehydrogenase and related
HRJ37_14415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HRJ37_14420	COG1116	anion transmembrane transporter activity
HRJ37_14425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HRJ37_14430	COG0494	nUDIX hydrolase
HRJ37_14435	COG2310	stress, protein
HRJ37_14450	COG4824	toxin secretion phage lysis holin
HRJ37_14460	COG0783	Belongs to the Dps family
HRJ37_14475	COG1854	S-ribosylhomocysteine lyase activity
HRJ37_14480	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HRJ37_14485	COG0288	reversible hydration of carbon dioxide
HRJ37_14490	COG0803	Belongs to the bacterial solute-binding protein 9 family
HRJ37_14490	COG3443	Belongs to the bacterial solute-binding protein 9 family
HRJ37_14500	COG1271	oxidase subunit
HRJ37_14505	COG1294	oxidase, subunit
HRJ37_14520	COG4948	Mandelate Racemase Muconate Lactonizing
HRJ37_14525	COG0318	PFAM AMP-dependent synthetase and ligase
HRJ37_14530	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HRJ37_14535	COG0596	Alpha beta hydrolase
HRJ37_14540	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HRJ37_14545	COG1169	isochorismate synthase
HRJ37_14550	COG1575	Belongs to the MenA family. Type 1 subfamily
HRJ37_14555	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HRJ37_14685	COG3859	Proton-coupled thiamine transporter YuaJ
HRJ37_14690	COG1247	-acetyltransferase
HRJ37_14695	COG3339	Conserved Protein
HRJ37_14700	COG0772	Belongs to the SEDS family
HRJ37_14705	COG0772	Belongs to the SEDS family
HRJ37_14710	COG2268	Band 7 protein
HRJ37_14715	COG1585	Membrane protein implicated in regulation of membrane protease activity
HRJ37_14720	COG2318	DinB family
HRJ37_14725	COG1454	alcohol dehydrogenase
HRJ37_14730	COG1012	belongs to the aldehyde dehydrogenase family
HRJ37_14735	COG1510	regulation of RNA biosynthetic process
HRJ37_14745	COG0457	Tetratricopeptide repeat
HRJ37_14755	COG5632	N-Acetylmuramoyl-L-alanine amidase
HRJ37_14755	COG3409	Peptidoglycan-binding domain 1 protein
HRJ37_14790	COG3778	Protein conserved in bacteria
HRJ37_14795	COG3299	homolog of phage Mu protein gp47
HRJ37_14800	COG3628	GPW Gp25 family protein
HRJ37_14810	COG4193	domain, Protein
HRJ37_14815	COG1652	LysM domain
HRJ37_14820	COG3953	SLT domain
HRJ37_14820	COG5280	Phage tail tape measure protein TP901
HRJ37_14820	COG5280	Phage tail tape measure protein TP901
HRJ37_14820	COG3953	SLT domain
HRJ37_14875	COG4653	Phage capsid family
HRJ37_14880	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HRJ37_14890	COG2369	cell adhesion
HRJ37_14895	COG5518	Phage portal protein
HRJ37_14900	COG1783	phage Terminase large subunit
HRJ37_14905	COG5484	DNA packaging
HRJ37_15015	COG0305	Participates in initiation and elongation during chromosome replication
HRJ37_15095	COG0582	viral genome integration into host DNA
HRJ37_15110	COG5632	N-Acetylmuramoyl-L-alanine amidase
HRJ37_15110	COG3409	Peptidoglycan-binding domain 1 protein
HRJ37_15165	COG3778	Protein conserved in bacteria
HRJ37_15170	COG3299	homolog of phage Mu protein gp47
HRJ37_15175	COG3628	GPW Gp25 family protein
HRJ37_15185	COG4193	domain, Protein
HRJ37_15190	COG1652	LysM domain
HRJ37_15195	COG3953	SLT domain
HRJ37_15195	COG5280	Phage tail tape measure protein TP901
HRJ37_15250	COG4653	Phage capsid family
HRJ37_15255	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HRJ37_15260	COG5518	Phage portal protein
HRJ37_15265	COG1783	phage Terminase large subunit
HRJ37_15270	COG5484	DNA packaging
HRJ37_15275	COG1595	DNA-templated transcription, initiation
HRJ37_15285	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HRJ37_15305	COG1396	sequence-specific DNA binding
HRJ37_15315	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HRJ37_15330	COG0628	permease
HRJ37_15340	COG0673	inositol 2-dehydrogenase activity
HRJ37_15345	COG0693	protein deglycase activity
HRJ37_15350	COG0840	transmembrane signaling receptor activity
HRJ37_15355	COG0840	transmembrane signaling receptor activity
HRJ37_15360	COG0840	transmembrane signaling receptor activity
HRJ37_15365	COG0840	transmembrane signaling receptor activity
HRJ37_15380	COG2070	2-Nitropropane dioxygenase
HRJ37_15385	COG0432	Pfam Uncharacterised protein family UPF0047
HRJ37_15390	COG1253	flavin adenine dinucleotide binding
HRJ37_15395	COG2738	Putative neutral zinc metallopeptidase
HRJ37_15405	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HRJ37_15420	COG0166	Belongs to the GPI family
HRJ37_15425	COG1979	alcohol dehydrogenase
HRJ37_15430	COG1979	alcohol dehydrogenase
HRJ37_15435	COG2155	Conserved Protein
HRJ37_15440	COG1098	S1 RNA binding domain
HRJ37_15445	COG0436	Aminotransferase
HRJ37_15450	COG1522	sequence-specific DNA binding
HRJ37_15455	COG2267	carboxylic ester hydrolase activity
HRJ37_15465	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HRJ37_15470	COG2205	protein histidine kinase activity
HRJ37_15485	COG5018	Exonuclease
HRJ37_15490	COG2814	Major facilitator Superfamily
HRJ37_15495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HRJ37_15500	COG3011	Protein conserved in bacteria
HRJ37_15510	COG3290	protein histidine kinase activity
HRJ37_15515	COG4565	transcriptional regulatory protein
HRJ37_15540	COG3493	citrate carrier protein
HRJ37_15550	COG2111	Na H antiporter
HRJ37_15550	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HRJ37_15555	COG2111	Na H antiporter
HRJ37_15560	COG1006	Multisubunit Na H antiporter MnhC subunit
HRJ37_15565	COG0651	ATP synthesis coupled electron transport
HRJ37_15570	COG1863	multisubunit Na H antiporter MnhE subunit
HRJ37_15575	COG2212	antiporter activity
HRJ37_15580	COG1320	monovalent cation:proton antiporter activity
HRJ37_15585	COG2050	protein possibly involved in aromatic compounds catabolism
HRJ37_15590	COG2197	response regulator
HRJ37_15595	COG4585	Histidine kinase
HRJ37_15605	COG0142	geranyltranstransferase activity
HRJ37_15620	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
HRJ37_15625	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HRJ37_15630	COG1335	isochorismatase
HRJ37_15635	COG5506	Protein of unknown function (DUF1694)
HRJ37_15655	COG0628	permease
HRJ37_15670	COG1418	mRNA catabolic process
HRJ37_15675	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ37_15685	COG1511	domain protein
HRJ37_15690	COG0433	COG0433 Predicted ATPase
HRJ37_15690	COG1674	ftsk spoiiie
HRJ37_15695	COG4499	WXG100 protein secretion system (Wss), protein YukC
HRJ37_15700	COG5417	Belongs to the EsaB family
HRJ37_15705	COG4842	Belongs to the WXG100 family
HRJ37_15710	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HRJ37_15710	COG2508	Transcriptional regulator
HRJ37_15715	COG0686	Belongs to the AlaDH PNT family
HRJ37_15720	COG1268	BioY protein
HRJ37_15725	COG2056	Na+-H+ antiporter family
HRJ37_15730	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HRJ37_15735	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
HRJ37_15740	COG3584	3D domain protein
HRJ37_15755	COG1252	NADH dehydrogenase
HRJ37_15760	COG0492	ferredoxin-NADP+ reductase activity
HRJ37_15775	COG0316	Belongs to the HesB IscA family
HRJ37_15780	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HRJ37_15785	COG4844	belongs to the
HRJ37_15790	COG1252	NADH dehydrogenase
HRJ37_15800	COG4837	Protein of unknown function (DUF1462)
HRJ37_15805	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HRJ37_15810	COG0823	Involved in the tonB-independent uptake of proteins
HRJ37_15810	COG1506	peptidase
HRJ37_15810	COG4946	Tricorn protease homolog
HRJ37_15815	COG0083	homoserine kinase activity
HRJ37_15820	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HRJ37_15825	COG0460	homoserine dehydrogenase
HRJ37_15830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HRJ37_15835	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HRJ37_15840	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HRJ37_15845	COG0647	UMP catabolic process
HRJ37_15850	COG2445	Protein of unknown function DUF86
HRJ37_15855	COG4470	Protein conserved in bacteria
HRJ37_15865	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HRJ37_15870	COG0739	heme binding
HRJ37_15890	COG3377	Domain of unknown function (DUF1805)
HRJ37_15895	COG0737	Belongs to the 5'-nucleotidase family
HRJ37_15900	COG1801	Protein of unknown function DUF72
HRJ37_15905	COG2508	Transcriptional regulator
HRJ37_15910	COG2140	Oxalate decarboxylase
HRJ37_15915	COG2814	Major facilitator Superfamily
HRJ37_15920	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HRJ37_15925	COG2356	endonuclease I
HRJ37_15940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HRJ37_15945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HRJ37_15950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HRJ37_15970	COG5002	protein histidine kinase activity
HRJ37_15970	COG0642	Histidine kinase
HRJ37_15975	COG0745	RESPONSE REGULATOR receiver
HRJ37_15980	COG2311	Membrane
HRJ37_15990	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HRJ37_16000	COG1309	transcriptional regulator
HRJ37_16005	COG0719	Fe-S assembly protein
HRJ37_16010	COG0822	iron-sulfur transferase activity
HRJ37_16015	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HRJ37_16020	COG0719	Fe-S assembly protein
HRJ37_16025	COG0396	ATPase activity
HRJ37_16035	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HRJ37_16040	COG1464	Belongs to the NlpA lipoprotein family
HRJ37_16045	COG2011	ABC-type metal ion transport system permease component
HRJ37_16050	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HRJ37_16060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HRJ37_16065	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HRJ37_16075	COG0509	glycine decarboxylation via glycine cleavage system
HRJ37_16080	COG1393	Belongs to the ArsC family
HRJ37_16085	COG1960	acyl-CoA dehydrogenase activity
HRJ37_16090	COG0183	Belongs to the thiolase family
HRJ37_16095	COG1024	Enoyl-CoA hydratase
HRJ37_16095	COG1250	3-hydroxyacyl-CoA dehydrogenase
HRJ37_16110	COG5577	PFAM Coat F domain
HRJ37_16120	COG1120	ATPase activity
HRJ37_16130	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ37_16135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HRJ37_16140	COG0745	RESPONSE REGULATOR receiver
HRJ37_16145	COG2770	Histidine kinase
HRJ37_16145	COG2205	protein histidine kinase activity
HRJ37_16155	COG1309	transcriptional regulator
HRJ37_16160	COG0114	fumarate hydratase activity
HRJ37_16170	COG0697	spore germination
HRJ37_16175	COG0814	amino acid
HRJ37_16190	COG2197	response regulator
HRJ37_16195	COG4585	Histidine kinase
HRJ37_16200	COG4758	membrane
HRJ37_16210	COG1842	Phage shock protein A
HRJ37_16215	COG4758	membrane
HRJ37_16220	COG2096	Adenosyltransferase
HRJ37_16225	COG1120	ATPase activity
HRJ37_16230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HRJ37_16235	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HRJ37_16245	COG2721	sulfolactate sulfo-lyase activity
HRJ37_16250	COG0246	Mannitol dehydrogenase
HRJ37_16255	COG1609	Transcriptional regulator
HRJ37_16260	COG1904	glucuronate isomerase
HRJ37_16265	COG2205	protein histidine kinase activity
HRJ37_16270	COG0745	RESPONSE REGULATOR receiver
HRJ37_16275	COG1120	ATPase activity
HRJ37_16280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HRJ37_16285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HRJ37_16290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HRJ37_16295	COG0531	amino acid
HRJ37_16310	COG1988	membrane-bound metal-dependent
HRJ37_16315	COG1368	sulfuric ester hydrolase activity
HRJ37_16320	COG0725	ABC transporter, periplasmic molybdate-binding protein
HRJ37_16325	COG4149	molybdate abc transporter
HRJ37_16330	COG0656	L-ascorbic acid biosynthetic process
HRJ37_16335	COG1940	carbohydrate kinase activity
HRJ37_16340	COG0025	NhaP-type Na H and K H
HRJ37_16345	COG2860	membrane
HRJ37_16350	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HRJ37_16355	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HRJ37_16360	COG2217	Heavy metal translocating P-type atpase
HRJ37_16365	COG1121	(ABC) transporter
HRJ37_16370	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HRJ37_16375	COG0803	Belongs to the bacterial solute-binding protein 9 family
HRJ37_16385	COG3226	Transcriptional regulator
HRJ37_16390	COG0784	Response regulator, receiver
HRJ37_16395	COG4191	Histidine kinase
HRJ37_16400	COG1027	Aspartate ammonia-lyase
HRJ37_16415	COG2217	Heavy metal translocating P-type atpase
HRJ37_16420	COG2608	mercury ion transmembrane transporter activity
HRJ37_16425	COG1937	Protein conserved in bacteria
HRJ37_16445	COG0463	Glycosyl transferase, family 2
HRJ37_16445	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HRJ37_16460	COG3409	Peptidoglycan-binding domain 1 protein
HRJ37_16460	COG5632	N-Acetylmuramoyl-L-alanine amidase
HRJ37_16465	COG4824	toxin secretion phage lysis holin
HRJ37_16495	COG1705	Flagellar rod assembly protein muramidase FlgJ
HRJ37_16505	COG3953	SLT domain
HRJ37_16505	COG5412	phage tail tape measure protein
HRJ37_16605	COG0582	viral genome integration into host DNA
HRJ37_16610	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HRJ37_16735	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HRJ37_16740	COG0557	exoribonuclease II activity
HRJ37_16745	COG1647	Serine aminopeptidase, S33
HRJ37_16750	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HRJ37_16755	COG2002	toxin-antitoxin pair type II binding
HRJ37_16760	COG1476	TRANSCRIPTIONal
HRJ37_16765	COG1396	sequence-specific DNA binding
HRJ37_16770	COG1396	sequence-specific DNA binding
HRJ37_16775	COG1733	regulation of RNA biosynthetic process
HRJ37_16780	COG1174	glycine betaine transport
HRJ37_16785	COG1732	Glycine betaine
HRJ37_16790	COG1174	glycine betaine transport
HRJ37_16795	COG1125	glycine betaine transport
HRJ37_16795	COG0517	IMP dehydrogenase activity
HRJ37_16800	COG1510	regulation of RNA biosynthetic process
HRJ37_16805	COG2095	MarC family integral membrane protein
HRJ37_16815	COG0456	acetyltransferase
HRJ37_16835	COG1131	(ABC) transporter
HRJ37_16845	COG0148	phosphopyruvate hydratase activity
HRJ37_16850	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HRJ37_16855	COG0149	triose-phosphate isomerase activity
HRJ37_16860	COG0126	phosphoglycerate kinase activity
HRJ37_16865	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HRJ37_16870	COG2390	Transcriptional regulator
HRJ37_16875	COG0833	amino acid
HRJ37_16880	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HRJ37_16885	COG3829	transcription factor binding
HRJ37_16890	COG2186	Transcriptional regulator
HRJ37_16895	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HRJ37_16905	COG0534	Mate efflux family protein
HRJ37_16910	COG4608	Belongs to the ABC transporter superfamily
HRJ37_16915	COG0444	Belongs to the ABC transporter superfamily
HRJ37_16920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HRJ37_16925	COG0601	transmembrane transport
HRJ37_16930	COG0747	negative chemotaxis
HRJ37_16935	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HRJ37_16940	COG0110	maltose O-acetyltransferase activity
HRJ37_16945	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HRJ37_16950	COG2244	polysaccharide biosynthetic process
HRJ37_16955	COG5039	Polysaccharide pyruvyl transferase
HRJ37_16960	COG1216	Glycosyl transferase, family 2
HRJ37_16970	COG0438	transferase activity, transferring glycosyl groups
HRJ37_16975	COG1215	transferase activity, transferring glycosyl groups
HRJ37_16980	COG0438	transferase activity, transferring glycosyl groups
HRJ37_16985	COG1086	Polysaccharide biosynthesis protein
HRJ37_16990	COG0489	protein tyrosine kinase activity
HRJ37_16995	COG3944	biosynthesis protein
HRJ37_17000	COG1396	sequence-specific DNA binding
HRJ37_17010	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HRJ37_17015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HRJ37_17020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HRJ37_17025	COG0726	polysaccharide deacetylase
HRJ37_17050	COG0601	transmembrane transport
HRJ37_17055	COG0747	negative chemotaxis
HRJ37_17060	COG1819	glycosyl
HRJ37_17065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HRJ37_17080	COG0740	serine-type endopeptidase activity
HRJ37_17085	COG1611	Belongs to the LOG family
HRJ37_17090	COG1694	Mazg nucleotide pyrophosphohydrolase
HRJ37_17095	COG0659	secondary active sulfate transmembrane transporter activity
HRJ37_17100	COG0288	reversible hydration of carbon dioxide
HRJ37_17105	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HRJ37_17115	COG1301	dicarboxylic acid transport
HRJ37_17120	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HRJ37_17125	COG1737	Transcriptional regulator
HRJ37_17130	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HRJ37_17135	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HRJ37_17140	COG1481	regulation of sporulation
HRJ37_17145	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HRJ37_17150	COG1660	Displays ATPase and GTPase activities
HRJ37_17155	COG1051	belongs to the nudix hydrolase family
HRJ37_17160	COG0492	ferredoxin-NADP+ reductase activity
HRJ37_17165	COG3883	PFAM NLP P60 protein
HRJ37_17165	COG0791	NLP P60 protein
HRJ37_17170	COG0457	Tetratricopeptide repeat
HRJ37_17175	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HRJ37_17175	COG0140	phosphoribosyl-ATP diphosphatase activity
HRJ37_17180	COG0107	imidazoleglycerol-phosphate synthase activity
HRJ37_17185	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HRJ37_17190	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HRJ37_17195	COG0131	Imidazoleglycerol-phosphate dehydratase
HRJ37_17200	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HRJ37_17205	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HRJ37_17210	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HRJ37_17215	COG4990	cell redox homeostasis
HRJ37_17220	COG2910	NAD(P)H-binding
HRJ37_17225	COG1959	2 iron, 2 sulfur cluster binding
HRJ37_17230	COG0110	maltose O-acetyltransferase activity
HRJ37_17235	COG0546	phosphoglycolate phosphatase activity
HRJ37_17240	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HRJ37_17245	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HRJ37_17250	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HRJ37_17255	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HRJ37_17260	COG0363	glucosamine-6-phosphate deaminase activity
HRJ37_17265	COG2188	Transcriptional regulator
HRJ37_17270	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HRJ37_17275	COG1950	PFAM Membrane protein of
HRJ37_17280	COG1983	PspC domain protein
HRJ37_17285	COG3595	metallopeptidase activity
HRJ37_17300	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HRJ37_17310	COG4897	Protein conserved in bacteria
HRJ37_17315	COG0574	Belongs to the PEP-utilizing enzyme family
HRJ37_17315	COG3848	Pyruvate phosphate dikinase
HRJ37_17320	COG1309	transcriptional regulator
HRJ37_17325	COG2814	Major facilitator Superfamily
HRJ37_17335	COG0745	RESPONSE REGULATOR receiver
HRJ37_17340	COG5002	protein histidine kinase activity
HRJ37_17345	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HRJ37_17350	COG0463	Glycosyl transferase, family 2
HRJ37_17355	COG1113	amino acid transport
HRJ37_17360	COG0778	Nitroreductase
HRJ37_17365	COG1733	regulation of RNA biosynthetic process
HRJ37_17370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HRJ37_17380	COG0793	Belongs to the peptidase S41A family
HRJ37_17380	COG3409	Peptidoglycan-binding domain 1 protein
HRJ37_17385	COG0730	response to heat
HRJ37_17390	COG0791	NLP P60 protein
HRJ37_17390	COG3883	PFAM NLP P60 protein
HRJ37_17395	COG2177	Part of the ABC transporter FtsEX involved in
HRJ37_17400	COG2884	Cell division ATP-binding protein ftsE
HRJ37_17405	COG2010	Cytochrome c
HRJ37_17410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HRJ37_17430	COG0653	protein targeting
HRJ37_17435	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HRJ37_17440	COG0840	transmembrane signaling receptor activity
HRJ37_17455	COG1516	flagellar protein fliS
HRJ37_17460	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HRJ37_17465	COG1334	flagellar protein FlaG
HRJ37_17470	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HRJ37_17475	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HRJ37_17485	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HRJ37_17490	COG1256	bacterial-type flagellum assembly
HRJ37_17490	COG4786	Flagellar basal body rod
HRJ37_17495	COG3418	PFAM FlgN family protein
HRJ37_17510	COG1040	competence protein
HRJ37_17520	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HRJ37_17525	COG1307	EDD domain protein, DegV family
HRJ37_17530	COG2197	response regulator
HRJ37_17535	COG4585	Histidine kinase
HRJ37_17540	COG1739	Uncharacterized protein family UPF0029
HRJ37_17545	COG1316	TRANSCRIPTIONal
HRJ37_17550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HRJ37_17555	COG0438	transferase activity, transferring glycosyl groups
HRJ37_17560	COG1215	transferase activity, transferring glycosyl groups
HRJ37_17565	COG3206	protein involved in exopolysaccharide biosynthesis
HRJ37_17570	COG3307	-O-antigen
HRJ37_17575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HRJ37_17580	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HRJ37_17585	COG0438	transferase activity, transferring glycosyl groups
HRJ37_17585	COG0297	glycogen (starch) synthase activity
HRJ37_17590	COG2244	polysaccharide biosynthetic process
HRJ37_17605	COG0860	N-Acetylmuramoyl-L-alanine amidase
HRJ37_17605	COG2247	cell wall binding repeat
HRJ37_17610	COG0860	N-Acetylmuramoyl-L-alanine amidase
HRJ37_17610	COG2247	cell wall binding repeat
HRJ37_17615	COG2247	cell wall binding repeat
HRJ37_17615	COG2385	sporulation resulting in formation of a cellular spore
HRJ37_17625	COG1316	TRANSCRIPTIONal
HRJ37_17630	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HRJ37_17635	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HRJ37_17640	COG1134	teichoic acid transport
HRJ37_17645	COG1682	transport, permease protein
HRJ37_17650	COG1216	Glycosyl transferase, family 2
HRJ37_17685	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HRJ37_17690	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
HRJ37_17695	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HRJ37_17700	COG4193	domain, Protein
HRJ37_17705	COG1482	cell wall glycoprotein biosynthetic process
HRJ37_17715	COG1175	transmembrane transport
HRJ37_17720	COG1653	transport
HRJ37_17725	COG2197	response regulator
HRJ37_17730	COG2972	Histidine kinase
HRJ37_17740	COG0454	-acetyltransferase
HRJ37_17745	COG0800	Aldolase
HRJ37_17750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HRJ37_17755	COG1609	Transcriptional regulator
HRJ37_17760	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HRJ37_17765	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ37_17770	COG0697	spore germination
HRJ37_17775	COG0814	amino acid
HRJ37_17790	COG2814	Major facilitator Superfamily
HRJ37_17795	COG1316	TRANSCRIPTIONal
HRJ37_17800	COG0561	phosphatase activity
HRJ37_17805	COG0791	NLP P60 protein
HRJ37_17815	COG2843	Capsule synthesis protein
HRJ37_17825	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HRJ37_17830	COG0697	spore germination
HRJ37_17845	COG1609	Transcriptional regulator
HRJ37_17850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HRJ37_17855	COG1869	D-ribose catabolic process
HRJ37_17860	COG1129	ABC transporter
HRJ37_17865	COG1172	Belongs to the binding-protein-dependent transport system permease family
HRJ37_17870	COG1879	ABC-type sugar transport system periplasmic component
HRJ37_17875	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HRJ37_17880	COG0583	DNA-binding transcription factor activity
HRJ37_17885	COG0028	Belongs to the TPP enzyme family
HRJ37_17890	COG3527	Alpha-acetolactate decarboxylase
HRJ37_17895	COG1522	sequence-specific DNA binding
HRJ37_17900	COG2059	Chromate
HRJ37_17905	COG2059	Chromate
HRJ37_17910	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HRJ37_17920	COG4715	Zinc finger, swim domain protein
HRJ37_17925	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HRJ37_17930	COG2202	Pas domain
HRJ37_17930	COG1366	Belongs to the anti-sigma-factor antagonist family
HRJ37_17935	COG0561	phosphatase activity
HRJ37_17950	COG1970	mechanosensitive ion channel activity
HRJ37_17955	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HRJ37_17960	COG0457	Tetratricopeptide repeat
HRJ37_17965	COG4786	Flagellar basal body rod
HRJ37_17970	COG4786	Flagellar basal body rod
HRJ37_17975	COG1077	Cell shape determining protein MreB Mrl
HRJ37_17980	COG1609	Transcriptional regulator
HRJ37_17985	COG1846	Transcriptional regulator
HRJ37_17995	COG0671	phosphoesterase, PA-phosphatase related
HRJ37_18000	COG0477	Major facilitator Superfamily
HRJ37_18005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HRJ37_18010	COG0765	amino acid transport
HRJ37_18015	COG1126	abc transporter atp-binding protein
HRJ37_18020	COG0004	ammonium transporteR
HRJ37_18025	COG0347	Belongs to the P(II) protein family
HRJ37_18030	COG0739	heme binding
HRJ37_18035	COG1247	-acetyltransferase
HRJ37_18050	COG0523	cobalamin synthesis protein
HRJ37_18055	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HRJ37_18060	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HRJ37_18065	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HRJ37_18070	COG2223	nitrite transmembrane transporter activity
HRJ37_18080	COG2304	oxidoreductase activity
HRJ37_18085	COG2304	oxidoreductase activity
HRJ37_18090	COG2385	sporulation resulting in formation of a cellular spore
HRJ37_18095	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HRJ37_18105	COG4836	Membrane
HRJ37_18115	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HRJ37_18120	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HRJ37_18125	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HRJ37_18130	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HRJ37_18135	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HRJ37_18140	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HRJ37_18145	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HRJ37_18150	COG0356	it plays a direct role in the translocation of protons across the membrane
HRJ37_18160	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HRJ37_18165	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HRJ37_18170	COG4475	Protein of unknown function (DUF436)
HRJ37_18175	COG0698	ribose 5-phosphate isomerase
HRJ37_18180	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HRJ37_18185	COG1971	Probably functions as a manganese efflux pump
HRJ37_18190	COG0009	L-threonylcarbamoyladenylate synthase
HRJ37_18195	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HRJ37_18210	COG2890	protein-(glutamine-N5) methyltransferase activity
HRJ37_18215	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HRJ37_18220	COG0789	Transcriptional regulator
HRJ37_18225	COG0679	Auxin Efflux Carrier
HRJ37_18230	COG0281	malic enzyme
HRJ37_18235	COG1435	thymidine kinase activity
HRJ37_18240	COG0254	rRNA binding
HRJ37_18245	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HRJ37_18250	COG1494	fructose-1,6-bisphosphatase
HRJ37_18255	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HRJ37_18260	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HRJ37_18265	COG0191	fructose-bisphosphate aldolase activity
HRJ37_18270	COG2204	response regulator
HRJ37_18275	COG4821	SIS domain
HRJ37_18280	COG0504	CTP synthase activity
HRJ37_18285	COG3343	RNA polymerase activity
HRJ37_18300	COG1960	acyl-CoA dehydrogenase activity
HRJ37_18305	COG1960	acyl-CoA dehydrogenase activity
HRJ37_18310	COG1250	3-hydroxyacyl-CoA dehydrogenase
HRJ37_18315	COG0183	Belongs to the thiolase family
HRJ37_18320	COG0247	lactate metabolic process
HRJ37_18320	COG2181	nitrate reductase activity
HRJ37_18325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HRJ37_18340	COG1619	proteins homologs of microcin C7 resistance protein MccF
HRJ37_18345	COG1132	(ABC) transporter
HRJ37_18350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HRJ37_18355	COG1619	proteins homologs of microcin C7 resistance protein MccF
HRJ37_18360	COG0018	arginyl-trna synthetase
HRJ37_18365	COG4506	Protein conserved in bacteria
HRJ37_18375	COG0010	Belongs to the arginase family
HRJ37_18380	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HRJ37_18385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HRJ37_18395	COG1994	Peptidase M50
HRJ37_18400	COG1942	4-Oxalocrotonate Tautomerase
HRJ37_18410	COG3465	dGTPase activity
HRJ37_18415	COG1078	dGTPase activity
HRJ37_18420	COG4844	belongs to the
HRJ37_18465	COG5444	nuclease activity
HRJ37_18495	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HRJ37_18505	COG0280	phosphate acetyltransferase
HRJ37_18515	COG2814	Major facilitator Superfamily
HRJ37_18520	COG1522	sequence-specific DNA binding
HRJ37_18525	COG2814	Major facilitator Superfamily
HRJ37_18530	COG0077	Prephenate dehydratase
HRJ37_18535	COG1917	Cupin 2, conserved barrel domain protein
HRJ37_18540	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ37_18545	COG0151	Belongs to the GarS family
HRJ37_18550	COG0436	Aminotransferase
HRJ37_18555	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ37_18560	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
HRJ37_18565	COG1091	dTDP-4-dehydrorhamnose reductase activity
HRJ37_18570	COG1088	dTDP-glucose 4,6-dehydratase activity
HRJ37_18575	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HRJ37_18580	COG3980	spore coat polysaccharide biosynthesis protein
HRJ37_18585	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
HRJ37_18590	COG2089	acid synthase
HRJ37_18595	COG0456	acetyltransferase
HRJ37_18600	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HRJ37_18605	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HRJ37_18610	COG0463	Glycosyl transferase, family 2
HRJ37_18630	COG2363	Small membrane protein
HRJ37_18635	COG2233	PERMEase
HRJ37_18645	COG1012	belongs to the aldehyde dehydrogenase family
HRJ37_18650	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HRJ37_18655	COG1216	Glycosyl transferase, family 2
HRJ37_18665	COG0351	phosphomethylpyrimidine kinase
HRJ37_18695	COG1621	beta-fructofuranosidase activity
HRJ37_18700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HRJ37_18700	COG1263	PTS System
HRJ37_18705	COG3711	transcriptional antiterminator
HRJ37_18715	COG1404	Belongs to the peptidase S8 family
HRJ37_18725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HRJ37_18730	COG0778	Nitroreductase
HRJ37_18735	COG0772	Belongs to the SEDS family
HRJ37_18745	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HRJ37_18750	COG1845	cytochrome c oxidase, subunit III
HRJ37_18755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HRJ37_18760	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HRJ37_18770	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
HRJ37_18775	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HRJ37_18780	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HRJ37_18795	COG2246	polysaccharide biosynthetic process
HRJ37_18815	COG3162	membrane
HRJ37_18820	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HRJ37_18845	COG0352	thiamine-phosphate diphosphorylase activity
HRJ37_18850	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HRJ37_18855	COG0583	DNA-binding transcription factor activity
HRJ37_18860	COG1380	Effector of murein hydrolase LrgA
HRJ37_18865	COG1346	cytolysis
HRJ37_18870	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HRJ37_18875	COG0346	lactoylglutathione lyase activity
HRJ37_18900	COG0765	amino acid transport
HRJ37_18905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HRJ37_18910	COG0457	Tetratricopeptide repeat
HRJ37_18920	COG2357	RelA SpoT domain protein
HRJ37_18925	COG1172	Belongs to the binding-protein-dependent transport system permease family
HRJ37_18930	COG1129	ABC transporter
HRJ37_18940	COG3420	alginic acid biosynthetic process
HRJ37_18945	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HRJ37_18955	COG1486	melibiose metabolic process
HRJ37_18960	COG1447	Phosphotransferase system cellobiose-specific component IIA
HRJ37_18965	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HRJ37_18970	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HRJ37_18975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HRJ37_18975	COG3711	transcriptional antiterminator
HRJ37_18990	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HRJ37_19005	COG1595	DNA-templated transcription, initiation
HRJ37_19015	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HRJ37_19020	COG4988	ABC transporter
HRJ37_19025	COG1294	oxidase, subunit
HRJ37_19030	COG1271	oxidase subunit
HRJ37_19040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HRJ37_19045	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HRJ37_19050	COG4509	Sortase family
HRJ37_19075	COG5386	Cell surface protein
HRJ37_19080	COG5386	Cell surface protein
HRJ37_19085	COG1733	regulation of RNA biosynthetic process
HRJ37_19090	COG2514	catechol 2,3-dioxygenase activity
HRJ37_19095	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HRJ37_19095	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HRJ37_19100	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HRJ37_19100	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HRJ37_19110	COG0726	polysaccharide deacetylase
HRJ37_19115	COG1447	Phosphotransferase system cellobiose-specific component IIA
HRJ37_19120	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HRJ37_19125	COG2723	6-phospho-beta-galactosidase activity
HRJ37_19130	COG1312	Catalyzes the dehydration of D-mannonate
HRJ37_19135	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HRJ37_19140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HRJ37_19140	COG3711	transcriptional antiterminator
HRJ37_19165	COG1757	Na H antiporter
HRJ37_19170	COG1027	Aspartate ammonia-lyase
HRJ37_19175	COG0252	asparaginase activity
HRJ37_19180	COG1396	sequence-specific DNA binding
HRJ37_19205	COG4842	Belongs to the WXG100 family
HRJ37_19210	COG2195	Cleaves the N-terminal amino acid of tripeptides
HRJ37_19225	COG1737	Transcriptional regulator
HRJ37_19230	COG2084	Dehydrogenase
HRJ37_19240	COG2610	gluconate transmembrane transporter activity
HRJ37_19245	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HRJ37_19265	COG2723	6-phospho-beta-galactosidase activity
HRJ37_19270	COG2190	(PTS) system
HRJ37_19270	COG1263	PTS System
HRJ37_19270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HRJ37_19275	COG3711	transcriptional antiterminator
HRJ37_19280	COG3878	Protein conserved in bacteria
HRJ37_19290	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HRJ37_19295	COG1122	ATPase activity
HRJ37_19300	COG4721	ABC-type cobalt transport system, permease component
HRJ37_19305	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HRJ37_19340	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HRJ37_19345	COG0778	Nitroreductase
HRJ37_19350	COG1846	Transcriptional regulator
HRJ37_19355	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HRJ37_19360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HRJ37_19365	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HRJ37_19370	COG2390	Transcriptional regulator
HRJ37_19380	COG2755	lipolytic protein G-D-S-L family
HRJ37_19380	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HRJ37_19385	COG0477	Major facilitator Superfamily
HRJ37_19390	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HRJ37_19395	COG2226	methyltransferase
HRJ37_19405	COG0561	phosphatase activity
HRJ37_19410	COG0789	Transcriptional regulator
HRJ37_19415	COG0673	inositol 2-dehydrogenase activity
HRJ37_19420	COG0840	transmembrane signaling receptor activity
HRJ37_19425	COG1113	amino acid transport
HRJ37_19430	COG4335	DNA alkylation repair
HRJ37_19440	COG1070	Carbohydrate kinase
HRJ37_19445	COG1737	Transcriptional regulator
HRJ37_19490	COG0583	DNA-binding transcription factor activity
HRJ37_19495	COG1609	Transcriptional regulator
HRJ37_19500	COG2182	Extracellular solute-binding protein
HRJ37_19505	COG1175	transmembrane transport
HRJ37_19510	COG3833	ABC-type maltose transport systems, permease component
HRJ37_19520	COG1874	Beta-galactosidase
HRJ37_19555	COG2851	Citrate transporter
HRJ37_19565	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HRJ37_19570	COG1131	(ABC) transporter
HRJ37_19575	COG2824	Alkylphosphonate utilization operon protein PhnA
HRJ37_19580	COG1929	Belongs to the glycerate kinase type-1 family
HRJ37_19585	COG2610	gluconate transmembrane transporter activity
HRJ37_19590	COG3835	regulator
HRJ37_19595	COG1309	transcriptional regulator
HRJ37_19600	COG2814	Major facilitator Superfamily
HRJ37_19610	COG1136	(ABC) transporter
HRJ37_19615	COG0457	Tetratricopeptide repeat
HRJ37_19620	COG3711	transcriptional antiterminator
HRJ37_19625	COG2723	6-phospho-beta-galactosidase activity
HRJ37_19630	COG1263	PTS System
HRJ37_19630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HRJ37_19630	COG2190	(PTS) system
HRJ37_19655	COG0494	nUDIX hydrolase
HRJ37_19670	COG1113	amino acid transport
HRJ37_19680	COG2814	Major facilitator Superfamily
HRJ37_19685	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HRJ37_19690	COG2814	Major facilitator Superfamily
HRJ37_19710	COG5444	nuclease activity
HRJ37_19725	COG2723	6-phospho-beta-galactosidase activity
HRJ37_19730	COG1263	PTS System
HRJ37_19730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HRJ37_19730	COG2190	(PTS) system
HRJ37_19735	COG2188	Transcriptional regulator
HRJ37_19745	COG0384	phenazine biosynthesis protein PhzF
HRJ37_19750	COG0583	DNA-binding transcription factor activity
HRJ37_19770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HRJ37_19785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HRJ37_19800	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HRJ37_19810	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HRJ37_19820	COG4720	Psort location CytoplasmicMembrane, score
HRJ37_19840	COG0456	acetyltransferase
HRJ37_19845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HRJ37_19850	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HRJ37_19855	COG4853	Protein conserved in bacteria
HRJ37_19860	COG4863	YycH protein
HRJ37_19865	COG5002	protein histidine kinase activity
HRJ37_19870	COG0745	RESPONSE REGULATOR receiver
HRJ37_19895	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HRJ37_19905	COG2311	Membrane
HRJ37_19910	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HRJ37_19915	COG1309	transcriptional regulator
HRJ37_19920	COG2124	cytochrome p450
HRJ37_19925	COG0346	lactoylglutathione lyase activity
HRJ37_19930	COG0305	Participates in initiation and elongation during chromosome replication
HRJ37_19945	COG2819	hydrolase of the alpha beta superfamily
HRJ37_19950	COG1028	Short-chain dehydrogenase reductase Sdr
HRJ37_19955	COG1169	isochorismate synthase
HRJ37_19960	COG1021	2,3-dihydroxybenzoate-AMP ligase
HRJ37_19965	COG3433	isochorismatase activity
HRJ37_19965	COG1535	isochorismatase
HRJ37_19970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HRJ37_19975	COG3251	PFAM MbtH domain protein
HRJ37_19980	COG2207	Transcriptional regulator
HRJ37_19980	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HRJ37_19985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HRJ37_19990	COG2819	hydrolase of the alpha beta superfamily
HRJ37_19995	COG3093	addiction module antidote protein HigA
HRJ37_20000	COG2807	transmembrane transport
HRJ37_20005	COG0359	binds to the 23S rRNA
HRJ37_20010	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
HRJ37_20015	COG4241	membrane
HRJ37_20020	COG1227	inorganic diphosphatase activity
HRJ37_20030	COG1595	DNA-templated transcription, initiation
HRJ37_20040	COG0753	catalase activity
HRJ37_20045	COG0655	NAD(P)H dehydrogenase (quinone) activity
HRJ37_20050	COG0400	carboxylic ester hydrolase activity
HRJ37_20055	COG0346	lactoylglutathione lyase activity
HRJ37_20060	COG1174	glycine betaine transport
HRJ37_20065	COG0517	IMP dehydrogenase activity
HRJ37_20065	COG1125	glycine betaine transport
HRJ37_20070	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HRJ37_20075	COG0629	single-stranded DNA binding
HRJ37_20080	COG0360	Binds together with S18 to 16S ribosomal RNA
HRJ37_20085	COG0012	GTP binding
HRJ37_20090	COG4481	Protein conserved in bacteria
HRJ37_20105	COG3949	Membrane
HRJ37_20115	COG1475	DNA binding
HRJ37_20120	COG1192	Involved in chromosome partitioning
HRJ37_20130	COG1475	DNA binding
HRJ37_20135	COG0357	Ribosomal RNA small subunit methyltransferase G
HRJ37_20140	COG0445	tRNA wobble uridine modification
HRJ37_20145	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HRJ37_20150	COG1847	R3H domain protein
HRJ37_20155	COG0706	membrane insertase activity
HRJ37_20160	COG0594	ribonuclease P activity
HRJ37_20165	COG0230	Belongs to the bacterial ribosomal protein bL34 family