locus-tag	class	description
NMH04_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NMH04_00010	COG0592	DNA-directed DNA polymerase activity
NMH04_00015	COG2501	S4 domain
NMH04_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NMH04_00030	COG0187	DNA topoisomerase II activity
NMH04_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NMH04_00070	COG0516	GMP reductase activity
NMH04_00070	COG0517	IMP dehydrogenase activity
NMH04_00075	COG1686	Belongs to the peptidase S11 family
NMH04_00085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NMH04_00090	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NMH04_00095	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NMH04_00100	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NMH04_00115	COG1428	Deoxynucleoside kinase
NMH04_00120	COG1428	Deoxynucleoside kinase
NMH04_00125	COG3858	chitin binding
NMH04_00125	COG1388	LysM domain
NMH04_00130	COG1335	isochorismatase
NMH04_00135	COG0590	tRNA wobble adenosine to inosine editing
NMH04_00145	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NMH04_00150	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NMH04_00155	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NMH04_00200	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
NMH04_00205	COG3853	Toxic anion resistance protein (TelA)
NMH04_00210	COG1982	Orn Lys Arg decarboxylase major
NMH04_00215	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NMH04_00220	COG3870	Protein conserved in bacteria
NMH04_00225	COG1728	Protein conserved in bacteria
NMH04_00230	COG0470	DNA polymerase III
NMH04_00235	COG1774	PSP1 C-terminal conserved region
NMH04_00240	COG4467	Involved in initiation control of chromosome replication
NMH04_00245	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NMH04_00250	COG2827	Endonuclease containing a URI domain
NMH04_00255	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NMH04_00260	COG2002	toxin-antitoxin pair type II binding
NMH04_00265	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NMH04_00265	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NMH04_00270	COG0084	hydrolase, TatD family'
NMH04_00275	COG3583	domain protein
NMH04_00275	COG3584	3D domain protein
NMH04_00280	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NMH04_00285	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NMH04_00295	COG4466	Protein conserved in bacteria
NMH04_00305	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NMH04_00310	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NMH04_00315	COG0251	oxidation-reduction process
NMH04_00320	COG2088	sporulation resulting in formation of a cellular spore
NMH04_00330	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NMH04_00335	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NMH04_00340	COG0193	aminoacyl-tRNA hydrolase activity
NMH04_00350	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NMH04_00355	COG2002	toxin-antitoxin pair type II binding
NMH04_00360	COG2244	polysaccharide biosynthetic process
NMH04_00365	COG3956	TIGRFAM MazG family protein
NMH04_00370	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NMH04_00385	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NMH04_00390	COG1098	S1 RNA binding domain
NMH04_00405	COG2208	phosphoserine phosphatase activity
NMH04_00410	COG2304	oxidoreductase activity
NMH04_00415	COG0515	serine threonine protein kinase
NMH04_00420	COG0037	tRNA processing
NMH04_00425	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NMH04_00430	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NMH04_00435	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NMH04_00440	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NMH04_00445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NMH04_00450	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NMH04_00455	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NMH04_00460	COG0512	Glutamine amidotransferase of anthranilate synthase
NMH04_00465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NMH04_00470	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NMH04_00475	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NMH04_00480	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NMH04_00485	COG1396	sequence-specific DNA binding
NMH04_00490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NMH04_00495	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NMH04_00575	COG4463	regulation of RNA biosynthetic process
NMH04_00580	COG3880	PFAM UvrB UvrC protein
NMH04_00585	COG3869	Catalyzes the specific phosphorylation of arginine residues in
NMH04_00590	COG0542	response to heat
NMH04_00595	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NMH04_00600	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NMH04_00605	COG4956	integral membrane protein (PIN domain superfamily)
NMH04_00610	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NMH04_00615	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NMH04_00620	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NMH04_00625	COG1045	serine acetyltransferase
NMH04_00630	COG0215	cysteine-tRNA ligase activity
NMH04_00635	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NMH04_00640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NMH04_00645	COG3688	RNA-binding protein containing a PIN domain
NMH04_00650	COG1595	DNA-templated transcription, initiation
NMH04_00655	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NMH04_00660	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NMH04_00665	COG0250	Participates in transcription elongation, termination and antitermination
NMH04_00675	COG0081	regulation of translation
NMH04_00680	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NMH04_00685	COG0222	ribosome binding
NMH04_00690	COG2813	Specifically methylates the guanine in position
NMH04_00695	COG0085	RNA polymerase activity
NMH04_00700	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NMH04_00705	COG1358	cellular component organization or biogenesis
NMH04_00710	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NMH04_00715	COG0049	tRNA binding
NMH04_00720	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NMH04_00725	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NMH04_00730	COG0596	Alpha beta hydrolase
NMH04_00740	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NMH04_00745	COG0088	Forms part of the polypeptide exit tunnel
NMH04_00750	COG0089	rRNA binding
NMH04_00755	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NMH04_00760	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NMH04_00765	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NMH04_00770	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NMH04_00775	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NMH04_00780	COG0255	Belongs to the universal ribosomal protein uL29 family
NMH04_00785	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NMH04_00790	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NMH04_00795	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NMH04_00800	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NMH04_00805	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NMH04_00810	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NMH04_00815	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NMH04_00820	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NMH04_00825	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NMH04_00830	COG1841	ribosomal large subunit assembly
NMH04_00835	COG0200	Binds to the 23S rRNA
NMH04_00840	COG0201	protein transport
NMH04_00845	COG0563	adenylate kinase activity
NMH04_00850	COG0024	Methionine aminopeptidase
NMH04_00855	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NMH04_00860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NMH04_00865	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NMH04_00870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NMH04_00875	COG0202	RNA polymerase activity
NMH04_00880	COG0203	ribosomal protein L17
NMH04_00885	COG1122	ATPase activity
NMH04_00890	COG1122	ATPase activity
NMH04_00895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NMH04_00900	COG0101	tRNA pseudouridine synthase activity
NMH04_00905	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NMH04_00910	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NMH04_00915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NMH04_00940	COG0860	N-Acetylmuramoyl-L-alanine amidase
NMH04_00945	COG0489	protein tyrosine kinase activity
NMH04_00955	COG2194	sulfuric ester hydrolase activity
NMH04_00960	COG0726	polysaccharide deacetylase
NMH04_00990	COG0659	secondary active sulfate transmembrane transporter activity
NMH04_00995	COG0385	Bile acid
NMH04_01000	COG3876	Protein conserved in bacteria
NMH04_01005	COG1472	Belongs to the glycosyl hydrolase 3 family
NMH04_01010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NMH04_01015	COG1263	PTS System
NMH04_01015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NMH04_01020	COG1737	Transcriptional regulator
NMH04_01025	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NMH04_01060	COG1595	DNA-templated transcription, initiation
NMH04_01065	COG5662	AntiSigma factor
NMH04_01070	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NMH04_01075	COG4856	YbbR-like protein
NMH04_01080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NMH04_01085	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NMH04_01100	COG1131	(ABC) transporter
NMH04_01110	COG1136	(ABC) transporter
NMH04_01120	COG1695	Transcriptional regulator
NMH04_01130	COG1131	(ABC) transporter
NMH04_01140	COG1413	lyase activity
NMH04_01145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NMH04_01160	COG2311	Membrane
NMH04_01180	COG1476	TRANSCRIPTIONal
NMH04_01190	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NMH04_01195	COG2207	Transcriptional regulator
NMH04_01200	COG1309	transcriptional regulator
NMH04_01215	COG1113	amino acid transport
NMH04_01220	COG0584	glycerophosphoryl diester phosphodiesterase
NMH04_01225	COG2271	Major facilitator Superfamily
NMH04_01235	COG1331	Highly conserved protein containing a thioredoxin domain
NMH04_01250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NMH04_01270	COG1937	Protein conserved in bacteria
NMH04_01275	COG2210	Belongs to the sulfur carrier protein TusA family
NMH04_01285	COG0425	Belongs to the sulfur carrier protein TusA family
NMH04_01285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NMH04_01290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NMH04_01290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NMH04_01295	COG0425	Belongs to the sulfur carrier protein TusA family
NMH04_01300	COG0730	response to heat
NMH04_01310	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NMH04_01315	COG2814	Major facilitator Superfamily
NMH04_01330	COG1846	Transcriptional regulator
NMH04_01335	COG1683	Conserved Protein
NMH04_01345	COG0656	L-ascorbic acid biosynthetic process
NMH04_01350	COG0371	Dehydrogenase
NMH04_01355	COG1054	Belongs to the UPF0176 family
NMH04_01360	COG0531	amino acid
NMH04_01370	COG3711	transcriptional antiterminator
NMH04_01375	COG1263	PTS System
NMH04_01375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NMH04_01375	COG2190	(PTS) system
NMH04_01380	COG2723	6-phospho-beta-galactosidase activity
NMH04_01395	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NMH04_01395	COG3711	transcriptional antiterminator
NMH04_01400	COG1940	carbohydrate kinase activity
NMH04_01405	COG0383	alpha-mannosidase activity
NMH04_01410	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NMH04_01415	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NMH04_01420	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NMH04_01420	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NMH04_01425	COG1404	Belongs to the peptidase S8 family
NMH04_01440	COG0833	amino acid
NMH04_01445	COG2040	homocysteine
NMH04_01450	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NMH04_01455	COG1695	Transcriptional regulator
NMH04_01470	COG2814	Major facilitator Superfamily
NMH04_01475	COG0456	acetyltransferase
NMH04_01490	COG1404	Belongs to the peptidase S8 family
NMH04_01500	COG1309	transcriptional regulator
NMH04_01505	COG1917	Cupin 2, conserved barrel domain protein
NMH04_01510	COG1063	alcohol dehydrogenase
NMH04_01515	COG1846	Transcriptional regulator
NMH04_01520	COG0318	PFAM AMP-dependent synthetase and ligase
NMH04_01525	COG0531	amino acid
NMH04_01535	COG0596	Alpha beta hydrolase
NMH04_01540	COG1115	amino acid carrier protein
NMH04_01545	COG2066	Belongs to the glutaminase family
NMH04_01550	COG4191	Histidine kinase
NMH04_01555	COG0784	Response regulator, receiver
NMH04_01560	COG3012	SEC-C Motif Domain Protein
NMH04_01560	COG1405	negative regulation of cell septum assembly
NMH04_01570	COG0667	Aldo Keto reductase
NMH04_01575	COG3290	protein histidine kinase activity
NMH04_01580	COG3279	Response regulator of the LytR AlgR family
NMH04_01585	COG4555	ABC transporter
NMH04_01590	COG1668	transmembrane transport
NMH04_01605	COG3773	Cell wall hydrolase
NMH04_01610	COG1028	Short-chain dehydrogenase reductase Sdr
NMH04_01620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMH04_01625	COG2310	stress, protein
NMH04_01630	COG2310	stress, protein
NMH04_01635	COG2310	stress, protein
NMH04_01640	COG0861	Integral membrane protein TerC family
NMH04_01670	COG3853	Toxic anion resistance protein (TelA)
NMH04_01675	COG0517	IMP dehydrogenase activity
NMH04_01675	COG4175	Glycine betaine
NMH04_01680	COG4176	ABC-type proline glycine betaine transport system permease component
NMH04_01685	COG2113	Glycine betaine
NMH04_01700	COG1473	amidohydrolase
NMH04_01705	COG1288	antiporter activity
NMH04_01710	COG0039	L-malate dehydrogenase activity
NMH04_01715	COG1620	l-lactate permease
NMH04_01720	COG1609	Transcriptional regulator
NMH04_01725	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NMH04_01730	COG0561	phosphatase activity
NMH04_01735	COG0673	inositol 2-dehydrogenase activity
NMH04_01740	COG0738	Major facilitator superfamily
NMH04_01745	COG1280	lysine exporter protein (LysE YggA)
NMH04_01760	COG3403	YqcI/YcgG family
NMH04_01765	COG1113	amino acid transport
NMH04_01770	COG3665	Urea carboxylase-associated protein
NMH04_01775	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NMH04_01790	COG0457	Tetratricopeptide repeat
NMH04_01795	COG3209	COG3209 Rhs family protein
NMH04_01805	COG1012	belongs to the aldehyde dehydrogenase family
NMH04_01810	COG0710	3-dehydroquinate dehydratase activity
NMH04_01815	COG0028	Belongs to the TPP enzyme family
NMH04_01825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NMH04_01830	COG2271	Major facilitator Superfamily
NMH04_01845	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NMH04_01850	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NMH04_01860	COG0477	Major facilitator Superfamily
NMH04_01865	COG2226	methyltransferase
NMH04_01870	COG0583	DNA-binding transcription factor activity
NMH04_01875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NMH04_01880	COG3458	cephalosporin-C deacetylase activity
NMH04_01890	COG3541	Predicted nucleotidyltransferase
NMH04_01895	COG0506	proline dehydrogenase activity
NMH04_01900	COG1012	belongs to the aldehyde dehydrogenase family
NMH04_01905	COG2508	Transcriptional regulator
NMH04_01910	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NMH04_01915	COG0765	amino acid transport
NMH04_01920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NMH04_01930	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NMH04_01935	COG1522	sequence-specific DNA binding
NMH04_01940	COG2746	aminoglycoside 3-N-acetyltransferase activity
NMH04_01950	COG0840	transmembrane signaling receptor activity
NMH04_01950	COG3290	protein histidine kinase activity
NMH04_01955	COG3209	COG3209 Rhs family protein
NMH04_01975	COG3842	ATPase activity
NMH04_01980	COG1176	ABC-type spermidine putrescine transport system, permease component I
NMH04_01990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NMH04_01995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NMH04_02000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NMH04_02015	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
NMH04_02020	COG0697	spore germination
NMH04_02025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NMH04_02035	COG2207	Transcriptional regulator
NMH04_02035	COG3708	Transcriptional regulator
NMH04_02045	COG2364	Membrane
NMH04_02050	COG0737	Belongs to the 5'-nucleotidase family
NMH04_02055	COG3764	Sortase (surface protein transpeptidase)
NMH04_02060	COG2002	toxin-antitoxin pair type II binding
NMH04_02065	COG1126	abc transporter atp-binding protein
NMH04_02070	COG0765	amino acid transport
NMH04_02075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NMH04_02080	COG0412	Dienelactone hydrolase
NMH04_02085	COG0833	amino acid
NMH04_02090	COG3104	oligopeptide transport
NMH04_02095	COG5434	Belongs to the glycosyl hydrolase 28 family
NMH04_02100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMH04_02105	COG0456	acetyltransferase
NMH04_02110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NMH04_02115	COG0765	amino acid transport
NMH04_02120	COG1126	abc transporter atp-binding protein
NMH04_02125	COG1473	amidohydrolase
NMH04_02130	COG2079	MmgE PrpD family protein
NMH04_02140	COG0745	RESPONSE REGULATOR receiver
NMH04_02145	COG3850	Histidine kinase
NMH04_02145	COG5002	protein histidine kinase activity
NMH04_02150	COG1366	Belongs to the anti-sigma-factor antagonist family
NMH04_02155	COG0527	aspartate kinase activity
NMH04_02160	COG2814	Major facilitator Superfamily
NMH04_02165	COG1309	transcriptional regulator
NMH04_02175	COG0640	Transcriptional regulator
NMH04_02185	COG0583	DNA-binding transcription factor activity
NMH04_02190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NMH04_02195	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NMH04_02200	COG0531	amino acid
NMH04_02205	COG1012	belongs to the aldehyde dehydrogenase family
NMH04_02210	COG2249	NAD(P)H dehydrogenase (quinone) activity
NMH04_02215	COG4549	nuclear export factor GLE1
NMH04_02220	COG1276	copper resistance
NMH04_02220	COG2372	response to copper ion
NMH04_02225	COG2213	PTS system mannitol-specific
NMH04_02230	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NMH04_02235	COG0246	Mannitol dehydrogenase
NMH04_02240	COG0840	transmembrane signaling receptor activity
NMH04_02275	COG0346	lactoylglutathione lyase activity
NMH04_02285	COG0561	phosphatase activity
NMH04_02300	COG0457	Tetratricopeptide repeat
NMH04_02305	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NMH04_02310	COG1914	H( )-stimulated, divalent metal cation uptake system
NMH04_02315	COG4336	lyase activity
NMH04_02320	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NMH04_02325	COG1984	allophanate hydrolase subunit 2
NMH04_02330	COG1414	Transcriptional regulator
NMH04_02335	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NMH04_02340	COG2755	lipolytic protein G-D-S-L family
NMH04_02350	COG3711	transcriptional antiterminator
NMH04_02355	COG2226	methyltransferase
NMH04_02360	COG1028	Short-chain dehydrogenase reductase Sdr
NMH04_02365	COG3871	stress protein (general stress protein 26)
NMH04_02385	COG2814	Major facilitator Superfamily
NMH04_02390	COG1802	Transcriptional regulator
NMH04_02395	COG1917	Cupin 2, conserved barrel domain protein
NMH04_02395	COG2207	Transcriptional regulator
NMH04_02400	COG0697	spore germination
NMH04_02405	COG0473	3-isopropylmalate dehydrogenase activity
NMH04_02410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NMH04_02410	COG0551	DNA topoisomerase type I activity
NMH04_02415	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
NMH04_02420	COG3706	GGDEF domain
NMH04_02425	COG5298	Protein conserved in bacteria
NMH04_02430	COG1215	transferase activity, transferring glycosyl groups
NMH04_02440	COG0531	amino acid
NMH04_02445	COG0028	Belongs to the TPP enzyme family
NMH04_02450	COG5444	nuclease activity
NMH04_02480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NMH04_02485	COG1914	H( )-stimulated, divalent metal cation uptake system
NMH04_02490	COG2261	transglycosylase associated protein
NMH04_02495	COG2217	Heavy metal translocating P-type atpase
NMH04_02500	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NMH04_02505	COG3290	protein histidine kinase activity
NMH04_02510	COG4565	transcriptional regulatory protein
NMH04_02515	COG1301	dicarboxylic acid transport
NMH04_02520	COG0628	permease
NMH04_02525	COG1301	dicarboxylic acid transport
NMH04_02530	COG1131	(ABC) transporter
NMH04_02535	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NMH04_02550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NMH04_02555	COG1181	Belongs to the D-alanine--D-alanine ligase family
NMH04_02560	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NMH04_02575	COG0513	Belongs to the DEAD box helicase family
NMH04_02580	COG3402	PFAM membrane-flanked domain
NMH04_02585	COG3428	Bacterial PH domain
NMH04_02590	COG0705	Rhomboid family
NMH04_02595	COG0736	holo-[acyl-carrier-protein] synthase activity
NMH04_02600	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NMH04_02605	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NMH04_02610	COG0864	Transcriptional regulator
NMH04_02615	COG2337	Toxic component of a toxin-antitoxin (TA) module
NMH04_02620	COG1366	Belongs to the anti-sigma-factor antagonist family
NMH04_02625	COG1366	Belongs to the anti-sigma-factor antagonist family
NMH04_02630	COG2172	sigma factor antagonist activity
NMH04_02635	COG2208	phosphoserine phosphatase activity
NMH04_02640	COG1366	Belongs to the anti-sigma-factor antagonist family
NMH04_02645	COG2172	sigma factor antagonist activity
NMH04_02650	COG1191	sigma factor activity
NMH04_02655	COG2208	phosphoserine phosphatase activity
NMH04_02660	COG2183	response to ionizing radiation
NMH04_02670	COG3091	SprT-like family
NMH04_02675	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NMH04_02680	COG0022	dehydrogenase e1 component
NMH04_02685	COG0508	dehydrogenase complex catalyzes the overall conversion of
NMH04_02690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NMH04_02695	COG3284	Transcriptional regulator
NMH04_02735	COG0582	viral genome integration into host DNA
NMH04_02740	COG2856	Zn peptidase
NMH04_02745	COG1396	sequence-specific DNA binding
NMH04_02770	COG1674	ftsk spoiiie
NMH04_02775	COG2946	Replication initiation factor
NMH04_02875	COG0433	COG0433 Predicted ATPase
NMH04_02880	COG5644	endopeptidase inhibitor activity
NMH04_02885	COG0791	NLP P60 protein
NMH04_02885	COG0741	lytic transglycosylase activity
NMH04_02895	COG0457	Tetratricopeptide repeat
NMH04_02910	COG1309	transcriptional regulator
NMH04_02915	COG0508	dehydrogenase complex catalyzes the overall conversion of
NMH04_02915	COG0596	Alpha beta hydrolase
NMH04_02920	COG1902	pentaerythritol trinitrate reductase activity
NMH04_02925	COG0300	oxidoreductase activity
NMH04_02935	COG1063	alcohol dehydrogenase
NMH04_02940	COG1278	Cold shock
NMH04_02945	COG1329	Transcriptional regulator
NMH04_02950	COG1064	alcohol dehydrogenase
NMH04_02955	COG0789	Transcriptional regulator
NMH04_02970	COG0477	Major facilitator Superfamily
NMH04_02975	COG0657	acetylesterase activity
NMH04_02985	COG4221	oxidoreductase activity
NMH04_02995	COG0252	asparaginase activity
NMH04_03000	COG2267	carboxylic ester hydrolase activity
NMH04_03020	COG2814	Major facilitator Superfamily
NMH04_03025	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NMH04_03030	COG2409	Drug exporters of the RND superfamily
NMH04_03035	COG4585	Histidine kinase
NMH04_03040	COG2197	response regulator
NMH04_03085	COG1309	transcriptional regulator
NMH04_03090	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NMH04_03095	COG1846	Transcriptional regulator
NMH04_03100	COG0778	Nitroreductase
NMH04_03115	COG1396	sequence-specific DNA binding
NMH04_03125	COG0456	acetyltransferase
NMH04_03135	COG4122	O-methyltransferase activity
NMH04_03145	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NMH04_03150	COG0697	spore germination
NMH04_03160	COG1301	dicarboxylic acid transport
NMH04_03200	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NMH04_03205	COG0802	atpase or kinase
NMH04_03210	COG1214	PFAM Peptidase M22, glycoprotease
NMH04_03215	COG0456	acetyltransferase
NMH04_03220	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NMH04_03225	COG0488	(ABC) transporter
NMH04_03230	COG0315	cyclic pyranopterin monophosphate synthase activity
NMH04_03235	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NMH04_03240	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NMH04_03245	COG0805	protein transport
NMH04_03260	COG1266	CAAX protease self-immunity
NMH04_03265	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NMH04_03270	COG0459	protein refolding
NMH04_03275	COG1846	Transcriptional regulator
NMH04_03280	COG0456	acetyltransferase
NMH04_03285	COG2808	Putative FMN-binding domain
NMH04_03315	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NMH04_03320	COG0823	Involved in the tonB-independent uptake of proteins
NMH04_03330	COG2132	Multicopper oxidase
NMH04_03335	COG1113	amino acid transport
NMH04_03340	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NMH04_03345	COG0714	Associated with various cellular activities
NMH04_03350	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
NMH04_03355	COG1305	Transglutaminase-like
NMH04_03360	COG0519	Catalyzes the synthesis of GMP from XMP
NMH04_03360	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NMH04_03365	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NMH04_03375	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NMH04_03405	COG3279	Response regulator of the LytR AlgR family
NMH04_03425	COG1595	DNA-templated transcription, initiation
NMH04_03435	COG2814	Major facilitator Superfamily
NMH04_03440	COG0583	DNA-binding transcription factor activity
NMH04_03445	COG2252	PERMEase
NMH04_03455	COG5583	Uncharacterized small protein (DUF2292)
NMH04_03460	COG3064	Membrane
NMH04_03465	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
NMH04_03475	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NMH04_03480	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NMH04_03485	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NMH04_03490	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NMH04_03495	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NMH04_03500	COG0047	phosphoribosylformylglycinamidine synthase activity
NMH04_03505	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NMH04_03510	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NMH04_03515	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NMH04_03520	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NMH04_03525	COG0138	bifunctional purine biosynthesis protein purh
NMH04_03530	COG0151	Belongs to the GarS family
NMH04_03550	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NMH04_03555	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NMH04_03560	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NMH04_03565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NMH04_03575	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NMH04_03580	COG4496	protein, YerC YecD
NMH04_03590	COG0069	glutamate synthase activity
NMH04_03605	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NMH04_03610	COG0210	DNA helicase
NMH04_03615	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NMH04_03620	COG4851	CamS sex pheromone cAM373 precursor
NMH04_03625	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NMH04_03630	COG1285	pathogenesis
NMH04_03635	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NMH04_03640	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NMH04_03645	COG0154	amidase activity
NMH04_03650	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NMH04_03655	COG1309	transcriptional regulator
NMH04_03660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NMH04_03665	COG1957	nucleoside hydrolase
NMH04_03670	COG1597	lipid kinase activity
NMH04_03675	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NMH04_03685	COG5444	nuclease activity
NMH04_03690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NMH04_03705	COG1959	2 iron, 2 sulfur cluster binding
NMH04_03710	COG0492	ferredoxin-NADP+ reductase activity
NMH04_03725	COG1486	melibiose metabolic process
NMH04_03735	COG2211	Major facilitator Superfamily
NMH04_03765	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NMH04_03770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NMH04_03775	COG1442	glycosyl transferase family 8
NMH04_03780	COG1216	Glycosyl transferase, family 2
NMH04_03785	COG1442	glycosyl transferase family 8
NMH04_03790	COG2223	nitrite transmembrane transporter activity
NMH04_03800	COG0471	metal ion transport
NMH04_03815	COG0071	Belongs to the small heat shock protein (HSP20) family
NMH04_03830	COG0531	amino acid
NMH04_03835	COG0457	Tetratricopeptide repeat
NMH04_03835	COG0463	Glycosyl transferase, family 2
NMH04_03840	COG0488	(ABC) transporter
NMH04_03845	COG1469	GTP cyclohydrolase I activity
NMH04_03850	COG0789	Transcriptional regulator
NMH04_03855	COG2814	Major facilitator Superfamily
NMH04_03860	COG0488	(ABC) transporter
NMH04_03865	COG0513	Belongs to the DEAD box helicase family
NMH04_03870	COG2130	NADP-dependent
NMH04_03890	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NMH04_03890	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NMH04_03895	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NMH04_03905	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NMH04_03905	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NMH04_03915	COG3290	protein histidine kinase activity
NMH04_03920	COG4565	transcriptional regulatory protein
NMH04_03925	COG3181	Tripartite tricarboxylate transporter family receptor
NMH04_03930	COG2851	Citrate transporter
NMH04_03940	COG3479	Phenolic acid decarboxylase
NMH04_03945	COG1695	Transcriptional regulator
NMH04_03950	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NMH04_03960	COG1254	Belongs to the acylphosphatase family
NMH04_03965	COG2258	MOSC domain
NMH04_03980	COG0024	Methionine aminopeptidase
NMH04_03985	COG1263	PTS System
NMH04_03985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NMH04_03990	COG3739	integral membrane protein
NMH04_04005	COG1368	sulfuric ester hydrolase activity
NMH04_04010	COG0076	glutamate decarboxylase activity
NMH04_04025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NMH04_04025	COG1263	PTS System
NMH04_04030	COG0366	Alpha amylase catalytic
NMH04_04035	COG2188	Transcriptional regulator
NMH04_04045	COG0737	Belongs to the 5'-nucleotidase family
NMH04_04050	COG0693	protein deglycase activity
NMH04_04055	COG4840	Belongs to the UPF0435 family
NMH04_04060	COG1115	amino acid carrier protein
NMH04_04065	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NMH04_04070	COG4980	gas vesicle protein
NMH04_04075	COG1295	ribonuclease BN
NMH04_04080	COG0477	Major facilitator Superfamily
NMH04_04090	COG0387	Pfam Sodium calcium exchanger
NMH04_04100	COG0217	transcriptional regulatory protein
NMH04_04110	COG0668	transmembrane transport
NMH04_04115	COG0535	radical SAM domain protein
NMH04_04125	COG0726	polysaccharide deacetylase
NMH04_04135	COG0598	Magnesium transport protein CorA
NMH04_04145	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NMH04_04150	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NMH04_04180	COG0789	Transcriptional regulator
NMH04_04185	COG2814	Major facilitator Superfamily
NMH04_04235	COG2076	Multidrug Resistance protein
NMH04_04240	COG2076	Multidrug Resistance protein
NMH04_04245	COG1309	transcriptional regulator
NMH04_04255	COG4637	Psort location Cytoplasmic, score
NMH04_04260	COG2755	lipolytic protein G-D-S-L family
NMH04_04265	COG0492	ferredoxin-NADP+ reductase activity
NMH04_04270	COG2169	Transcriptional regulator
NMH04_04275	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NMH04_04280	COG1132	(ABC) transporter
NMH04_04285	COG1742	UPF0060 membrane protein
NMH04_04290	COG1595	DNA-templated transcription, initiation
NMH04_04310	COG2318	DinB family
NMH04_04320	COG1846	Transcriptional regulator
NMH04_04325	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NMH04_04325	COG0392	lysyltransferase activity
NMH04_04345	COG0778	Nitroreductase
NMH04_04360	COG1090	epimerase
NMH04_04365	COG2137	regulation of response to DNA damage stimulus
NMH04_04390	COG0463	Glycosyl transferase, family 2
NMH04_04395	COG4485	Bacterial membrane protein, YfhO
NMH04_04400	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NMH04_04415	COG2140	Oxalate decarboxylase
NMH04_04425	COG1191	sigma factor activity
NMH04_04470	COG1988	membrane-bound metal-dependent
NMH04_04475	COG1194	a g-specific adenine glycosylase
NMH04_04485	COG1028	Short-chain dehydrogenase reductase Sdr
NMH04_04500	COG3557	Belongs to the UPF0374 family
NMH04_04505	COG1132	(ABC) transporter
NMH04_04510	COG0444	Belongs to the ABC transporter superfamily
NMH04_04515	COG4608	Belongs to the ABC transporter superfamily
NMH04_04520	COG0747	negative chemotaxis
NMH04_04525	COG0601	transmembrane transport
NMH04_04530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMH04_04535	COG4129	membrane
NMH04_04540	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NMH04_04545	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NMH04_04550	COG0735	belongs to the Fur family
NMH04_04700	COG1368	sulfuric ester hydrolase activity
NMH04_04705	COG0681	Belongs to the peptidase S26 family
NMH04_04710	COG2873	o-acetylhomoserine
NMH04_04725	COG1131	(ABC) transporter
NMH04_04755	COG3382	B3 4 domain protein
NMH04_04760	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NMH04_04770	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NMH04_04775	COG2766	serine protein kinase
NMH04_04780	COG2718	Belongs to the UPF0229 family
NMH04_04785	COG1566	PFAM secretion protein HlyD family protein
NMH04_04790	COG2814	Major facilitator Superfamily
NMH04_04795	COG0655	NAD(P)H dehydrogenase (quinone) activity
NMH04_04805	COG1278	Cold shock
NMH04_04810	COG3706	GGDEF domain
NMH04_04835	COG5577	PFAM Coat F domain
NMH04_04840	COG5002	protein histidine kinase activity
NMH04_04845	COG0737	Belongs to the 5'-nucleotidase family
NMH04_04845	COG1525	nuclease
NMH04_04845	COG4085	toxin activity
NMH04_04850	COG3764	Sortase (surface protein transpeptidase)
NMH04_04855	COG0564	pseudouridine synthase activity
NMH04_04865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NMH04_04870	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NMH04_04870	COG3153	acetyltransferase
NMH04_04890	COG3835	regulator
NMH04_04895	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NMH04_04900	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NMH04_04905	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NMH04_04910	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NMH04_04915	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NMH04_04920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NMH04_04925	COG2203	Gaf domain
NMH04_04925	COG4585	Histidine kinase
NMH04_04930	COG2197	response regulator
NMH04_04945	COG0753	catalase activity
NMH04_04950	COG1959	2 iron, 2 sulfur cluster binding
NMH04_04955	COG1017	nitric oxide dioxygenase activity
NMH04_04955	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NMH04_04960	COG2719	SpoVR family
NMH04_04965	COG1785	Belongs to the alkaline phosphatase family
NMH04_04970	COG0791	NLP P60 protein
NMH04_04970	COG1388	LysM domain
NMH04_04985	COG1595	DNA-templated transcription, initiation
NMH04_04990	COG0204	Acyl-transferase
NMH04_04995	COG1253	flavin adenine dinucleotide binding
NMH04_05000	COG0789	Transcriptional regulator
NMH04_05005	COG1253	flavin adenine dinucleotide binding
NMH04_05020	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NMH04_05025	COG0584	glycerophosphoryl diester phosphodiesterase
NMH04_05035	COG0668	transmembrane transport
NMH04_05040	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NMH04_05045	COG0726	polysaccharide deacetylase
NMH04_05050	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NMH04_05055	COG0589	response to stress
NMH04_05060	COG1132	(ABC) transporter
NMH04_05065	COG1132	(ABC) transporter
NMH04_05070	COG0702	epimerase
NMH04_05080	COG3842	ATPase activity
NMH04_05085	COG2508	Transcriptional regulator
NMH04_05095	COG0189	ligase activity
NMH04_05100	COG0189	ligase activity
NMH04_05105	COG4399	Belongs to the UPF0754 family
NMH04_05110	COG3679	Belongs to the UPF0342 family
NMH04_05115	COG0561	phosphatase activity
NMH04_05120	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NMH04_05130	COG0475	glutathione-regulated potassium exporter activity
NMH04_05135	COG0490	domain, Protein
NMH04_05145	COG1024	Enoyl-CoA hydratase
NMH04_05155	COG0420	3'-5' exonuclease activity
NMH04_05160	COG4717	serine-type aminopeptidase activity
NMH04_05165	COG3481	metal-dependent phosphohydrolase, HD sub domain
NMH04_05175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NMH04_05205	COG1846	Transcriptional regulator
NMH04_05210	COG4980	gas vesicle protein
NMH04_05225	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NMH04_05230	COG0537	adenosine 5'-monophosphoramidase activity
NMH04_05235	COG1131	(ABC) transporter
NMH04_05240	COG4473	ABC transporter
NMH04_05250	COG1473	amidohydrolase
NMH04_05260	COG2329	Antibiotic biosynthesis monooxygenase
NMH04_05265	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NMH04_05270	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NMH04_05275	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NMH04_05280	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NMH04_05285	COG1309	transcriptional regulator
NMH04_05290	COG1511	domain protein
NMH04_05295	COG1363	Peptidase, m42
NMH04_05300	COG1301	dicarboxylic acid transport
NMH04_05310	COG1234	tRNA 3'-trailer cleavage
NMH04_05315	COG0095	Lipoate-protein ligase
NMH04_05320	COG0318	PFAM AMP-dependent synthetase and ligase
NMH04_05330	COG0501	Belongs to the peptidase M48B family
NMH04_05335	COG1404	Belongs to the peptidase S8 family
NMH04_05340	COG0406	alpha-ribazole phosphatase activity
NMH04_05345	COG0840	transmembrane signaling receptor activity
NMH04_05350	COG0723	plastoquinol--plastocyanin reductase activity
NMH04_05350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NMH04_05355	COG1028	Short-chain dehydrogenase reductase Sdr
NMH04_05365	COG4903	ComK protein
NMH04_05380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NMH04_05385	COG2814	Major facilitator Superfamily
NMH04_05390	COG2732	(Barnase) inhibitor
NMH04_05395	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMH04_05400	COG4605	iron ion homeostasis
NMH04_05405	COG4604	ABC transporter, ATP-binding protein
NMH04_05410	COG4607	ABC-type enterochelin transport system periplasmic component
NMH04_05415	COG1316	TRANSCRIPTIONal
NMH04_05430	COG0398	Pfam SNARE associated Golgi protein
NMH04_05435	COG0681	Belongs to the peptidase S26 family
NMH04_05440	COG3180	Ammonia monooxygenase
NMH04_05455	COG2259	Doxx family
NMH04_05460	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
NMH04_05465	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NMH04_05470	COG1074	ATP-dependent DNA helicase activity
NMH04_05475	COG0420	3'-5' exonuclease activity
NMH04_05480	COG0419	ATPase involved in DNA repair
NMH04_05485	COG1403	HNH endonuclease
NMH04_05525	COG5337	Spore coat protein CotH
NMH04_05535	COG0179	Fumarylacetoacetate (FAA) hydrolase
NMH04_05550	COG0367	asparagine synthase
NMH04_05565	COG1562	ergosterol biosynthetic process
NMH04_05570	COG0534	Mate efflux family protein
NMH04_05575	COG1917	Cupin 2, conserved barrel domain protein
NMH04_05575	COG2207	Transcriptional regulator
NMH04_05600	COG0076	glutamate decarboxylase activity
NMH04_05640	COG0646	methionine synthase
NMH04_05640	COG1410	methionine synthase
NMH04_05645	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NMH04_05645	COG0646	methionine synthase
NMH04_05650	COG1666	GTP binding
NMH04_05655	COG2996	Protein conserved in bacteria
NMH04_05660	COG1744	ABC transporter substrate-binding protein PnrA-like
NMH04_05665	COG0840	transmembrane signaling receptor activity
NMH04_05670	COG1307	EDD domain protein, DegV family
NMH04_05675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NMH04_05695	COG0561	phosphatase activity
NMH04_05700	COG1073	alpha beta
NMH04_05705	COG2151	metal-sulfur cluster biosynthetic enzyme
NMH04_05715	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NMH04_05720	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NMH04_05725	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NMH04_05730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NMH04_05735	COG0505	Belongs to the CarA family
NMH04_05740	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NMH04_05745	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NMH04_05755	COG2814	Major facilitator Superfamily
NMH04_05765	COG2267	carboxylic ester hydrolase activity
NMH04_05775	COG1744	ABC transporter substrate-binding protein PnrA-like
NMH04_05790	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NMH04_05795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NMH04_05800	COG5504	Zn-dependent protease
NMH04_05805	COG0444	Belongs to the ABC transporter superfamily
NMH04_05810	COG4608	Belongs to the ABC transporter superfamily
NMH04_05820	COG0601	transmembrane transport
NMH04_05825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMH04_05835	COG0180	Tryptophanyl-tRNA synthetase
NMH04_05840	COG4166	transmembrane transport
NMH04_05845	COG0601	transmembrane transport
NMH04_05850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMH04_05855	COG0444	Belongs to the ABC transporter superfamily
NMH04_05860	COG4608	Belongs to the ABC transporter superfamily
NMH04_05870	COG0456	acetyltransferase
NMH04_05875	COG1393	Belongs to the ArsC family
NMH04_05880	COG0861	Integral membrane protein TerC family
NMH04_05885	COG4862	establishment of competence for transformation
NMH04_05890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NMH04_05900	COG1164	Oligoendopeptidase f
NMH04_05910	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NMH04_05915	COG2346	COG2346, Truncated hemoglobins
NMH04_05920	COG0741	lytic transglycosylase activity
NMH04_05925	COG4116	CYTH
NMH04_05935	COG2357	RelA SpoT domain protein
NMH04_05940	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NMH04_05945	COG0564	pseudouridine synthase activity
NMH04_05950	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NMH04_05955	COG0475	glutathione-regulated potassium exporter activity
NMH04_05955	COG0569	domain protein
NMH04_05960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NMH04_05965	COG0352	thiamine-phosphate diphosphorylase activity
NMH04_05975	COG2104	thiamine diphosphate biosynthetic process
NMH04_05980	COG2022	thiamine diphosphate biosynthetic process
NMH04_05985	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NMH04_05990	COG0351	phosphomethylpyrimidine kinase
NMH04_05995	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NMH04_06050	COG0210	DNA helicase
NMH04_06060	COG2153	protein acetylation
NMH04_06065	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NMH04_06070	COG2382	esterase
NMH04_06075	COG0626	cystathionine gamma-synthase activity
NMH04_06080	COG0626	cystathionine gamma-synthase activity
NMH04_06150	COG0825	malonyl-CoA metabolic process
NMH04_06175	COG0457	Tetratricopeptide repeat
NMH04_06230	COG0583	DNA-binding transcription factor activity
NMH04_06250	COG0583	DNA-binding transcription factor activity
NMH04_06255	COG2807	transmembrane transport
NMH04_06290	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NMH04_06315	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NMH04_06320	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NMH04_06325	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NMH04_06330	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NMH04_06350	COG4195	phage-related replication protein
NMH04_06355	COG2856	Zn peptidase
NMH04_06360	COG3409	Peptidoglycan-binding domain 1 protein
NMH04_06360	COG5632	N-Acetylmuramoyl-L-alanine amidase
NMH04_06375	COG0306	phosphate transporter
NMH04_06380	COG1392	Phosphate transport regulator
NMH04_06390	COG0405	Gamma-glutamyltransferase
NMH04_06395	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NMH04_06405	COG4208	sulfate ABC transporter
NMH04_06410	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NMH04_06420	COG3775	system Galactitol-specific IIC component
NMH04_06435	COG1063	alcohol dehydrogenase
NMH04_06440	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NMH04_06445	COG0022	dehydrogenase e1 component
NMH04_06445	COG0508	dehydrogenase complex catalyzes the overall conversion of
NMH04_06450	COG0508	dehydrogenase complex catalyzes the overall conversion of
NMH04_06455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NMH04_06460	COG1028	Short-chain dehydrogenase reductase Sdr
NMH04_06465	COG1028	Short-chain dehydrogenase reductase Sdr
NMH04_06470	COG2390	Transcriptional regulator
NMH04_06480	COG0531	amino acid
NMH04_06485	COG0346	lactoylglutathione lyase activity
NMH04_06495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NMH04_06500	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NMH04_06505	COG2362	D-Aminopeptidase
NMH04_06510	COG0601	transmembrane transport
NMH04_06515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMH04_06520	COG0444	Belongs to the ABC transporter superfamily
NMH04_06525	COG4166	transmembrane transport
NMH04_06530	COG1619	proteins homologs of microcin C7 resistance protein MccF
NMH04_06535	COG4948	Mandelate Racemase Muconate Lactonizing
NMH04_06540	COG0791	NLP P60 protein
NMH04_06545	COG4608	Belongs to the ABC transporter superfamily
NMH04_06550	COG1834	amidinotransferase
NMH04_06555	COG1607	acyl-coa hydrolase
NMH04_06560	COG1695	Transcriptional regulator
NMH04_06575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NMH04_06585	COG2076	Multidrug Resistance protein
NMH04_06590	COG2076	Multidrug Resistance protein
NMH04_06600	COG0788	formyltetrahydrofolate deformylase activity
NMH04_06605	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NMH04_06610	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NMH04_06615	COG0457	Tetratricopeptide repeat
NMH04_06625	COG1764	response to oxidative stress
NMH04_06630	COG1846	Transcriptional regulator
NMH04_06635	COG1764	response to oxidative stress
NMH04_06640	COG0590	tRNA wobble adenosine to inosine editing
NMH04_06645	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NMH04_06650	COG1404	Belongs to the peptidase S8 family
NMH04_06665	COG0745	RESPONSE REGULATOR receiver
NMH04_06670	COG5002	protein histidine kinase activity
NMH04_06670	COG3850	Histidine kinase
NMH04_06675	COG3212	peptidase
NMH04_06680	COG3212	peptidase
NMH04_06690	COG2239	Acts as a magnesium transporter
NMH04_06700	COG0583	DNA-binding transcription factor activity
NMH04_06710	COG0789	Transcriptional regulator
NMH04_06725	COG1846	Transcriptional regulator
NMH04_06730	COG5001	Diguanylate cyclase
NMH04_06730	COG3300	MHYT domain
NMH04_06735	COG0586	Pfam SNARE associated Golgi protein
NMH04_06745	COG1191	sigma factor activity
NMH04_06765	COG0501	Belongs to the peptidase M48B family
NMH04_06770	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NMH04_06775	COG2323	membrane
NMH04_06790	COG3594	Acyltransferase
NMH04_06795	COG5002	protein histidine kinase activity
NMH04_06800	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NMH04_06805	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NMH04_06810	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NMH04_06815	COG0436	Aminotransferase
NMH04_06820	COG1850	ribulose-bisphosphate carboxylase activity
NMH04_06825	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NMH04_06830	COG0235	Class ii aldolase
NMH04_06835	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NMH04_06845	COG3852	Histidine kinase
NMH04_06850	COG1846	Transcriptional regulator
NMH04_06855	COG1360	Flagellar Motor Protein
NMH04_06860	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NMH04_06865	COG0542	response to heat
NMH04_06870	COG3949	Membrane
NMH04_06875	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NMH04_06880	COG0720	synthase
NMH04_06885	COG0602	queuosine metabolic process
NMH04_06890	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NMH04_06900	COG4873	Protein conserved in bacteria
NMH04_06910	COG3773	Cell wall hydrolase
NMH04_06915	COG2244	polysaccharide biosynthetic process
NMH04_06920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NMH04_06925	COG2217	Heavy metal translocating P-type atpase
NMH04_06930	COG0006	proline dipeptidase activity
NMH04_06935	COG1609	Transcriptional regulator
NMH04_06940	COG3711	transcriptional antiterminator
NMH04_06945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NMH04_06945	COG2190	(PTS) system
NMH04_06945	COG1263	PTS System
NMH04_06950	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NMH04_06955	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NMH04_06965	COG1533	DNA photolyase activity
NMH04_06970	COG0840	transmembrane signaling receptor activity
NMH04_06980	COG2084	Dehydrogenase
NMH04_06985	COG2340	Cysteine-rich secretory protein family
NMH04_06990	COG0768	penicillin binding
NMH04_06995	COG4191	Histidine kinase
NMH04_07000	COG0436	Aminotransferase
NMH04_07005	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NMH04_07015	COG1714	RDD family
NMH04_07025	COG0784	Response regulator, receiver
NMH04_07025	COG0835	chemotaxis
NMH04_07045	COG2814	Major facilitator Superfamily
NMH04_07050	COG1376	ErfK ybiS ycfS ynhG family protein
NMH04_07055	COG1408	metallophosphoesterase
NMH04_07060	COG1028	Short-chain dehydrogenase reductase Sdr
NMH04_07065	COG2200	EAL domain
NMH04_07070	COG3546	catalase activity
NMH04_07075	COG4703	Protein of unknown function (DUF1797)
NMH04_07080	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
NMH04_07090	COG0517	IMP dehydrogenase activity
NMH04_07095	COG0583	DNA-binding transcription factor activity
NMH04_07105	COG0716	FMN binding
NMH04_07115	COG0716	FMN binding
NMH04_07120	COG2171	N-acyltransferase activity
NMH04_07125	COG1473	amidohydrolase
NMH04_07135	COG0668	transmembrane transport
NMH04_07140	COG0450	alkyl hydroperoxide reductase
NMH04_07145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NMH04_07160	COG0746	molybdenum cofactor guanylyltransferase activity
NMH04_07165	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NMH04_07170	COG0303	'Molybdopterin
NMH04_07175	COG1763	Mo-molybdopterin cofactor biosynthetic process
NMH04_07180	COG0314	molybdopterin synthase activity
NMH04_07185	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NMH04_07200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NMH04_07205	COG1136	(ABC) transporter
NMH04_07210	COG0577	efflux transmembrane transporter activity
NMH04_07215	COG1349	DNA-binding transcription factor activity
NMH04_07220	COG1105	Belongs to the carbohydrate kinase PfkB family
NMH04_07225	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NMH04_07225	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NMH04_07225	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NMH04_07230	COG0681	Belongs to the peptidase S26 family
NMH04_07240	COG0488	(ABC) transporter
NMH04_07245	COG2309	aminopeptidase activity
NMH04_07255	COG1077	Cell shape determining protein MreB Mrl
NMH04_07260	COG2002	toxin-antitoxin pair type II binding
NMH04_07265	COG3852	Histidine kinase
NMH04_07270	COG2105	PFAM AIG2 family protein
NMH04_07270	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
NMH04_07275	COG0569	domain protein
NMH04_07280	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NMH04_07285	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NMH04_07290	COG5503	Protein of unknown function (DUF1447)
NMH04_07295	COG0561	phosphatase activity
NMH04_07300	COG0242	peptide deformylase activity
NMH04_07315	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NMH04_07320	COG0022	dehydrogenase e1 component
NMH04_07325	COG0508	dehydrogenase complex catalyzes the overall conversion of
NMH04_07330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NMH04_07335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NMH04_07345	COG1982	Orn Lys Arg decarboxylase major
NMH04_07350	COG4476	Belongs to the UPF0223 family
NMH04_07355	COG4493	Belongs to the UPF0637 family
NMH04_07365	COG0483	inositol monophosphate 1-phosphatase activity
NMH04_07380	COG1595	DNA-templated transcription, initiation
NMH04_07400	COG1217	gtp-binding protein TYPA
NMH04_07410	COG4896	Protein conserved in bacteria
NMH04_07420	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NMH04_07425	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NMH04_07430	COG2066	Belongs to the glutaminase family
NMH04_07435	COG4838	Belongs to the UPF0358 family
NMH04_07440	COG0772	Belongs to the SEDS family
NMH04_07445	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NMH04_07450	COG0415	Belongs to the DNA photolyase family
NMH04_07455	COG1612	heme a metabolic process
NMH04_07460	COG0109	protoheme IX farnesyltransferase activity
NMH04_07465	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NMH04_07465	COG2010	Cytochrome c
NMH04_07470	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NMH04_07475	COG1845	cytochrome c oxidase, subunit III
NMH04_07480	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NMH04_07485	COG3336	cytochrome c oxidase
NMH04_07495	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
NMH04_07500	COG2340	Cysteine-rich secretory protein family
NMH04_07520	COG3679	Belongs to the UPF0342 family
NMH04_07525	COG4471	UPF0298 protein
NMH04_07530	COG0742	ribosomal rna small subunit methyltransferase
NMH04_07535	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NMH04_07540	COG3314	Sporulation integral membrane protein YlbJ
NMH04_07545	COG1752	Esterase of the alpha-beta hydrolase superfamily
NMH04_07550	COG3480	Lon protease (S16) C-terminal proteolytic domain
NMH04_07560	COG1399	metal-binding, possibly nucleic acid-binding protein
NMH04_07565	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NMH04_07575	COG0454	-acetyltransferase
NMH04_07580	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NMH04_07585	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NMH04_07590	COG2001	Belongs to the MraZ family
NMH04_07595	COG0275	rRNA processing
NMH04_07600	COG4839	cell division protein FtsL
NMH04_07605	COG0768	penicillin binding
NMH04_07610	COG0768	penicillin binding
NMH04_07615	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NMH04_07620	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NMH04_07625	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NMH04_07630	COG0772	Belongs to the SEDS family
NMH04_07635	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NMH04_07640	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NMH04_07645	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NMH04_07650	COG3879	Bacterial protein of unknown function (DUF881)
NMH04_07655	COG3879	Bacterial protein of unknown function (DUF881)
NMH04_07660	COG3856	small basic protein
NMH04_07665	COG0849	cell division
NMH04_07670	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NMH04_07675	COG1404	Belongs to the peptidase S8 family
NMH04_07675	COG4412	M6 family metalloprotease domain protein
NMH04_07685	COG1191	sigma factor activity
NMH04_07690	COG1191	sigma factor activity
NMH04_07695	COG2390	Transcriptional regulator
NMH04_07710	COG3730	PTS system glucitol sorbitol-specific
NMH04_07715	COG3732	PTS system glucitol sorbitol-specific
NMH04_07725	COG1119	ATPase activity
NMH04_07730	COG1873	PFAM PRC-barrel domain
NMH04_07735	COG1496	oxidoreductase activity
NMH04_07740	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NMH04_07745	COG1799	cell septum assembly
NMH04_07750	COG0762	integral membrane protein
NMH04_07755	COG2302	S4 RNA-binding domain
NMH04_07760	COG3599	regulation of cell shape
NMH04_07765	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NMH04_07770	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NMH04_07775	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NMH04_07780	COG0564	pseudouridine synthase activity
NMH04_07785	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NMH04_07790	COG2233	PERMEase
NMH04_07795	COG0540	Belongs to the ATCase OTCase family
NMH04_07800	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NMH04_07805	COG0505	Belongs to the CarA family
NMH04_07810	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NMH04_07815	COG0543	2 iron, 2 sulfur cluster binding
NMH04_07820	COG0167	dihydroorotate dehydrogenase activity
NMH04_07825	COG0284	orotidine-5'-phosphate decarboxylase activity
NMH04_07830	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NMH04_07840	COG0175	sulfate reduction
NMH04_07845	COG0306	phosphate transporter
NMH04_07850	COG2046	Belongs to the sulfate adenylyltransferase family
NMH04_07855	COG0529	Catalyzes the synthesis of activated sulfate
NMH04_07860	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NMH04_07865	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
NMH04_07870	COG1648	precorrin-2 dehydrogenase activity
NMH04_07880	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NMH04_07885	COG1561	YicC-like family, N-terminal region
NMH04_07890	COG2052	Domain of unknown function (DUF370)
NMH04_07895	COG0194	GDP metabolic process
NMH04_07900	COG1758	RNA polymerase activity
NMH04_07905	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NMH04_07910	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NMH04_07915	COG0242	peptide deformylase activity
NMH04_07920	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NMH04_07925	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NMH04_07925	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NMH04_07930	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NMH04_07935	COG0631	protein serine/threonine phosphatase activity
NMH04_07940	COG2815	serine threonine protein kinase
NMH04_07940	COG0515	serine threonine protein kinase
NMH04_07945	COG1162	GTPase activity
NMH04_07950	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NMH04_07955	COG1564	THIamine pyrophosphokinase
NMH04_07965	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NMH04_07970	COG1302	Protein conserved in bacteria
NMH04_07975	COG1461	Dihydroxyacetone kinase
NMH04_07980	COG1760	l-serine dehydratase
NMH04_07985	COG1760	l-serine dehydratase
NMH04_07990	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NMH04_07995	COG1349	DNA-binding transcription factor activity
NMH04_08000	COG0416	fatty acid biosynthetic process
NMH04_08005	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NMH04_08010	COG1028	Short-chain dehydrogenase reductase Sdr
NMH04_08015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NMH04_08025	COG1196	nuclear chromosome segregation
NMH04_08030	COG0552	protein localization to endoplasmic reticulum
NMH04_08035	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NMH04_08040	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NMH04_08045	COG0228	four-way junction DNA binding
NMH04_08050	COG1837	Belongs to the UPF0109 family
NMH04_08060	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NMH04_08065	COG0336	Belongs to the RNA methyltransferase TrmD family
NMH04_08070	COG0335	large ribosomal subunit rRNA binding
NMH04_08075	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NMH04_08080	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NMH04_08090	COG2257	FlhB HrpN YscU SpaS Family
NMH04_08095	COG0045	succinate-CoA ligase (ADP-forming) activity
NMH04_08100	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NMH04_08105	COG0758	DNA mediated transformation
NMH04_08110	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NMH04_08115	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NMH04_08120	COG4974	Belongs to the 'phage' integrase family
NMH04_08125	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NMH04_08130	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NMH04_08135	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NMH04_08140	COG1815	bacterial-type flagellum-dependent cell motility
NMH04_08145	COG1558	bacterial-type flagellum-dependent cell motility
NMH04_08150	COG1677	Flagellar hook-basal body complex protein FliE
NMH04_08155	COG1766	The M ring may be actively involved in energy transduction
NMH04_08160	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NMH04_08165	COG1317	bacterial-type flagellum organization
NMH04_08170	COG1157	protein secretion by the type III secretion system
NMH04_08175	COG2882	bacterial-type flagellum organization
NMH04_08180	COG3334	PFAM MgtE intracellular
NMH04_08185	COG3144	bacterial-type flagellum assembly
NMH04_08190	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NMH04_08195	COG4786	Flagellar basal body rod
NMH04_08200	COG1582	Flagellar protein (FlbD)
NMH04_08205	COG1580	Controls the rotational direction of flagella during chemotaxis
NMH04_08210	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NMH04_08215	COG1776	CheC inhibitor of MCP methylation
NMH04_08215	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NMH04_08220	COG2201	protein-glutamate methylesterase activity
NMH04_08225	COG3190	flagellar
NMH04_08230	COG1338	Plays a role in the flagellum-specific transport system
NMH04_08235	COG1987	bacterial-type flagellum assembly
NMH04_08240	COG1684	flagellar biosynthetic protein fliR
NMH04_08245	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NMH04_08250	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NMH04_08255	COG1419	protein localization to endoplasmic reticulum
NMH04_08260	COG0455	bacterial-type flagellum organization
NMH04_08265	COG2201	protein-glutamate methylesterase activity
NMH04_08270	COG0643	Histidine kinase
NMH04_08270	COG2198	Histidine kinase
NMH04_08275	COG0835	chemotaxis
NMH04_08280	COG1776	CheC inhibitor of MCP methylation
NMH04_08290	COG1191	sigma factor activity
NMH04_08305	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NMH04_08310	COG0528	UMP kinase activity
NMH04_08315	COG0233	cytoplasmic translational termination
NMH04_08320	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NMH04_08325	COG4589	Belongs to the CDS family
NMH04_08330	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NMH04_08335	COG0750	zinc metalloprotease
NMH04_08340	COG0442	prolyl-tRNA aminoacylation
NMH04_08345	COG2176	DNA-directed DNA polymerase activity
NMH04_08360	COG3693	PFAM glycoside hydrolase, family 10
NMH04_08370	COG0779	Required for maturation of 30S ribosomal subunits
NMH04_08375	COG0195	Participates in both transcription termination and antitermination
NMH04_08380	COG2740	Nucleic-acid-binding protein implicated in transcription termination
NMH04_08385	COG1358	cellular component organization or biogenesis
NMH04_08390	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NMH04_08395	COG1550	Protein conserved in bacteria
NMH04_08400	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NMH04_08405	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NMH04_08410	COG0196	riboflavin kinase activity
NMH04_08415	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NMH04_08420	COG1185	polyribonucleotide nucleotidyltransferase activity
NMH04_08425	COG0726	polysaccharide deacetylase
NMH04_08430	COG0612	Peptidase, M16
NMH04_08435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NMH04_08445	COG1132	(ABC) transporter
NMH04_08450	COG1132	(ABC) transporter
NMH04_08485	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
NMH04_08505	COG1028	Short-chain dehydrogenase reductase Sdr
NMH04_08510	COG1028	Short-chain dehydrogenase reductase Sdr
NMH04_08515	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NMH04_08520	COG1260	myo-inositol-1-phosphate synthase
NMH04_08565	COG0367	asparagine synthase
NMH04_08570	COG1873	PFAM PRC-barrel domain
NMH04_08575	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NMH04_08580	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NMH04_08585	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NMH04_08590	COG0527	aspartate kinase activity
NMH04_08600	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NMH04_08605	COG0740	serine-type endopeptidase activity
NMH04_08615	COG1674	ftsk spoiiie
NMH04_08615	COG4980	gas vesicle protein
NMH04_08620	COG2188	Transcriptional regulator
NMH04_08625	COG2814	Major facilitator Superfamily
NMH04_08630	COG1033	growth of symbiont in host cell
NMH04_08630	COG2409	Drug exporters of the RND superfamily
NMH04_08635	COG0612	Peptidase, M16
NMH04_08640	COG0612	Peptidase, M16
NMH04_08650	COG1033	growth of symbiont in host cell
NMH04_08650	COG2409	Drug exporters of the RND superfamily
NMH04_08655	COG0300	oxidoreductase activity
NMH04_08670	COG1426	Protein conserved in bacteria
NMH04_08675	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NMH04_08680	COG1546	Belongs to the CinA family
NMH04_08680	COG1058	Belongs to the CinA family
NMH04_08685	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NMH04_08690	COG1418	mRNA catabolic process
NMH04_08695	COG1692	metallophosphoesterase
NMH04_08700	COG2359	stage V sporulation protein S
NMH04_08705	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NMH04_08710	COG1063	alcohol dehydrogenase
NMH04_08715	COG0156	8-amino-7-oxononanoate synthase activity
NMH04_08720	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NMH04_08725	COG4550	Control of competence regulator ComK, YlbF/YmcA
NMH04_08735	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NMH04_08740	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NMH04_08745	COG0582	viral genome integration into host DNA
NMH04_08755	COG1396	sequence-specific DNA binding
NMH04_08770	COG3646	Phage regulatory protein
NMH04_08770	COG3645	SOS response
NMH04_08815	COG0305	Participates in initiation and elongation during chromosome replication
NMH04_08915	COG5280	Phage tail tape measure protein TP901
NMH04_08915	COG3953	SLT domain
NMH04_08965	COG3409	Peptidoglycan-binding domain 1 protein
NMH04_08965	COG5632	N-Acetylmuramoyl-L-alanine amidase
NMH04_08980	COG0457	Tetratricopeptide repeat
NMH04_09005	COG1329	Transcriptional regulator
NMH04_09010	COG4195	phage-related replication protein
NMH04_09015	COG0457	Tetratricopeptide repeat
NMH04_09020	COG1404	Belongs to the peptidase S8 family
NMH04_09025	COG4195	phage-related replication protein
NMH04_09030	COG1764	response to oxidative stress
NMH04_09035	COG2076	Multidrug Resistance protein
NMH04_09060	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NMH04_09065	COG1923	regulation of RNA biosynthetic process
NMH04_09080	COG1780	Probably involved in ribonucleotide reductase function
NMH04_09085	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NMH04_09090	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NMH04_09095	COG4112	unkown
NMH04_09105	COG0464	growth
NMH04_09110	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NMH04_09115	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
NMH04_09120	COG0789	Transcriptional regulator
NMH04_09125	COG0174	glutamine synthetase
NMH04_09130	COG5444	nuclease activity
NMH04_09170	COG0494	nUDIX hydrolase
NMH04_09200	COG0457	Tetratricopeptide repeat
NMH04_09210	COG5444	nuclease activity
NMH04_09235	COG5646	InterPro IPR014922
NMH04_09255	COG0457	Tetratricopeptide repeat
NMH04_09265	COG3619	membrane
NMH04_09270	COG1793	dna ligase
NMH04_09270	COG3285	dna ligase
NMH04_09275	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NMH04_09280	COG4876	unkown
NMH04_09290	COG1959	2 iron, 2 sulfur cluster binding
NMH04_09295	COG0702	epimerase
NMH04_09325	COG4555	ABC transporter
NMH04_09330	COG0247	lactate metabolic process
NMH04_09335	COG1139	Iron-sulfur cluster binding protein
NMH04_09340	COG1556	Lactate utilization protein
NMH04_09360	COG2323	membrane
NMH04_09365	COG1309	transcriptional regulator
NMH04_09370	COG2124	cytochrome p450
NMH04_09370	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NMH04_09375	COG3591	Belongs to the peptidase S1B family
NMH04_09380	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NMH04_09385	COG3209	COG3209 Rhs family protein
NMH04_09390	COG1366	Belongs to the anti-sigma-factor antagonist family
NMH04_09405	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NMH04_09410	COG1388	LysM domain
NMH04_09415	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NMH04_09420	COG4224	UPF0291 protein
NMH04_09425	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NMH04_09435	COG3763	UPF0154 protein
NMH04_09445	COG0785	Cytochrome C biogenesis protein
NMH04_09450	COG4846	Membrane protein involved in cytochrome C biogenesis
NMH04_09460	COG0071	Belongs to the small heat shock protein (HSP20) family
NMH04_09475	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NMH04_09480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NMH04_09500	COG0824	Thioesterase
NMH04_09510	COG4841	protein insertion into membrane
NMH04_09515	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NMH04_09520	COG1832	CoA-binding protein
NMH04_09525	COG0187	DNA topoisomerase II activity
NMH04_09530	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NMH04_09540	COG0738	Major facilitator superfamily
NMH04_09545	COG0473	3-isopropylmalate dehydrogenase activity
NMH04_09555	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NMH04_09560	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NMH04_09565	COG0640	Transcriptional regulator
NMH04_09575	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NMH04_09580	COG0251	oxidation-reduction process
NMH04_09620	COG0657	acetylesterase activity
NMH04_09635	COG2205	protein histidine kinase activity
NMH04_09640	COG0745	RESPONSE REGULATOR receiver
NMH04_09650	COG3507	Belongs to the glycosyl hydrolase 43 family
NMH04_09655	COG1012	belongs to the aldehyde dehydrogenase family
NMH04_09660	COG1486	melibiose metabolic process
NMH04_09665	COG0395	ABC-type sugar transport system, permease component
NMH04_09670	COG1175	transmembrane transport
NMH04_09675	COG1653	transport
NMH04_09680	COG1609	Transcriptional regulator
NMH04_09685	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NMH04_09700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NMH04_09705	COG0456	acetyltransferase
NMH04_09710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NMH04_09730	COG1846	Transcriptional regulator
NMH04_09735	COG2814	Major facilitator Superfamily
NMH04_09745	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NMH04_09745	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NMH04_09745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NMH04_09750	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NMH04_09750	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NMH04_09750	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NMH04_09755	COG1105	Belongs to the carbohydrate kinase PfkB family
NMH04_09765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NMH04_09790	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NMH04_09795	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NMH04_09805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NMH04_09810	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NMH04_09815	COG1024	Enoyl-CoA hydratase
NMH04_09820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NMH04_09825	COG0511	ligase activity, forming carbon-carbon bonds
NMH04_09830	COG0439	Biotin carboxylase
NMH04_09835	COG0318	PFAM AMP-dependent synthetase and ligase
NMH04_09840	COG1960	acyl-CoA dehydrogenase activity
NMH04_09845	COG1649	PFAM Uncharacterised BCR, COG1649
NMH04_09850	COG2365	Tyrosine phosphatase family
NMH04_09855	COG1349	DNA-binding transcription factor activity
NMH04_09860	COG1942	4-Oxalocrotonate Tautomerase
NMH04_09870	COG3835	regulator
NMH04_09875	COG0277	FAD linked oxidase domain protein
NMH04_09880	COG0247	lactate metabolic process
NMH04_09900	COG0166	Belongs to the GPI family
NMH04_09905	COG2246	polysaccharide biosynthetic process
NMH04_09910	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NMH04_09915	COG0586	Pfam SNARE associated Golgi protein
NMH04_09920	COG1587	Uroporphyrinogen-III synthase
NMH04_09930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMH04_09950	COG0534	Mate efflux family protein
NMH04_09955	COG2027	D-alanyl-D-alanine carboxypeptidase
NMH04_09960	COG4677	pectinesterase activity
NMH04_09965	COG2323	membrane
NMH04_09970	COG2146	nitrite reductase [NAD(P)H] activity
NMH04_09975	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NMH04_09980	COG0243	molybdopterin cofactor binding
NMH04_09985	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NMH04_09990	COG2223	nitrite transmembrane transporter activity
NMH04_09995	COG0493	'glutamate synthase
NMH04_10000	COG0067	glutamate synthase
NMH04_10000	COG0069	glutamate synthase activity
NMH04_10000	COG0070	glutamate synthase
NMH04_10005	COG0583	DNA-binding transcription factor activity
NMH04_10015	COG1132	(ABC) transporter
NMH04_10020	COG0789	Transcriptional regulator
NMH04_10020	COG4978	Transcriptional regulator
NMH04_10025	COG0454	-acetyltransferase
NMH04_10030	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NMH04_10035	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NMH04_10040	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NMH04_10050	COG0243	molybdopterin cofactor binding
NMH04_10060	COG1070	Carbohydrate kinase
NMH04_10065	COG2115	Belongs to the xylose isomerase family
NMH04_10070	COG1940	carbohydrate kinase activity
NMH04_10080	COG2211	Major facilitator Superfamily
NMH04_10085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NMH04_10090	COG1994	Peptidase M50
NMH04_10110	COG1309	transcriptional regulator
NMH04_10115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NMH04_10120	COG3708	Transcriptional regulator
NMH04_10125	COG2378	regulation of single-species biofilm formation
NMH04_10135	COG0640	Transcriptional regulator
NMH04_10140	COG0531	amino acid
NMH04_10145	COG0741	lytic transglycosylase activity
NMH04_10150	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NMH04_10155	COG2079	MmgE PrpD family protein
NMH04_10160	COG0372	Belongs to the citrate synthase family
NMH04_10165	COG2322	membrane
NMH04_10175	COG1388	LysM domain
NMH04_10175	COG3584	3D domain protein
NMH04_10180	COG0514	ATP-dependent DNA helicase (RecQ)
NMH04_10190	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NMH04_10215	COG1012	belongs to the aldehyde dehydrogenase family
NMH04_10220	COG1657	PFAM Prenyltransferase squalene oxidase
NMH04_10225	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NMH04_10230	COG0385	Bile acid
NMH04_10235	COG0508	dehydrogenase complex catalyzes the overall conversion of
NMH04_10240	COG0567	Dehydrogenase, E1 component
NMH04_10245	COG4548	von Willebrand factor, type A
NMH04_10250	COG0714	Associated with various cellular activities
NMH04_10255	COG2032	superoxide dismutase activity
NMH04_10260	COG0791	NLP P60 protein
NMH04_10260	COG1388	LysM domain
NMH04_10265	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NMH04_10270	COG0534	Mate efflux family protein
NMH04_10275	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NMH04_10280	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NMH04_10290	COG2962	Rard protein
NMH04_10305	COG1733	regulation of RNA biosynthetic process
NMH04_10310	COG0778	Nitroreductase
NMH04_10320	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NMH04_10325	COG0793	Belongs to the peptidase S41A family
NMH04_10325	COG3409	Peptidoglycan-binding domain 1 protein
NMH04_10330	COG2226	methyltransferase
NMH04_10340	COG1876	peptidase activity
NMH04_10345	COG0813	purine-nucleoside phosphorylase activity
NMH04_10355	COG0671	phosphoesterase, PA-phosphatase related
NMH04_10370	COG4479	Belongs to the UPF0346 family
NMH04_10380	COG1509	lysine 2,3-aminomutase activity
NMH04_10385	COG3829	transcription factor binding
NMH04_10390	COG0463	Glycosyl transferase, family 2
NMH04_10405	COG4641	Protein conserved in bacteria
NMH04_10415	COG1086	Polysaccharide biosynthesis protein
NMH04_10420	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NMH04_10425	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NMH04_10430	COG1846	Transcriptional regulator
NMH04_10450	COG4698	Protein conserved in bacteria
NMH04_10455	COG2755	lipolytic protein G-D-S-L family
NMH04_10460	COG1999	signal sequence binding
NMH04_10475	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NMH04_10480	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NMH04_10485	COG1272	protein, Hemolysin III
NMH04_10490	COG0204	Acyl-transferase
NMH04_10495	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NMH04_10500	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NMH04_10505	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NMH04_10515	COG2521	methyltransferase
NMH04_10515	COG2136	Putative SAM-dependent methyltransferase
NMH04_10525	COG0129	dihydroxy-acid dehydratase activity
NMH04_10530	COG1413	lyase activity
NMH04_10535	COG1418	mRNA catabolic process
NMH04_10540	COG0386	Belongs to the glutathione peroxidase family
NMH04_10545	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NMH04_10550	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NMH04_10555	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NMH04_10565	COG1278	Cold shock
NMH04_10580	COG0328	RNA-DNA hybrid ribonuclease activity
NMH04_10585	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NMH04_10590	COG0328	RNA-DNA hybrid ribonuclease activity
NMH04_10600	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NMH04_10610	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NMH04_10615	COG1755	Isoprenylcysteine carboxyl methyltransferase
NMH04_10620	COG3424	synthase
NMH04_10625	COG0456	acetyltransferase
NMH04_10625	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NMH04_10630	COG0726	polysaccharide deacetylase
NMH04_10635	COG2233	PERMEase
NMH04_10640	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NMH04_10645	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NMH04_10650	COG1199	ATP-dependent helicase activity
NMH04_10660	COG0116	Belongs to the methyltransferase superfamily
NMH04_10670	COG3599	regulation of cell shape
NMH04_10675	COG4474	Belongs to the UPF0398 family
NMH04_10685	COG3359	exonuclease
NMH04_10690	COG1111	helicase
NMH04_10690	COG1205	dead DEAH box helicase
NMH04_10695	COG1902	pentaerythritol trinitrate reductase activity
NMH04_10700	COG2190	(PTS) system
NMH04_10705	COG0071	Belongs to the small heat shock protein (HSP20) family
NMH04_10735	COG3331	DNA recombination
NMH04_10740	COG4499	WXG100 protein secretion system (Wss), protein YukC
NMH04_10740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NMH04_10750	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NMH04_10755	COG3935	DnaD domain protein
NMH04_10760	COG0017	Asparaginyl-tRNA synthetase
NMH04_10765	COG5353	protein conserved in bacteria
NMH04_10775	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NMH04_10775	COG1199	ATP-dependent helicase activity
NMH04_10780	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NMH04_10785	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NMH04_10790	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NMH04_10800	COG0617	tRNA 3'-terminal CCA addition
NMH04_10805	COG0438	transferase activity, transferring glycosyl groups
NMH04_10810	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NMH04_10815	COG1803	Methylglyoxal synthase
NMH04_10820	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NMH04_10825	COG1694	Mazg nucleotide pyrophosphohydrolase
NMH04_10830	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NMH04_10840	COG4347	Protein of unknown function (DUF1405)
NMH04_10845	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NMH04_10845	COG2010	Cytochrome c
NMH04_10850	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NMH04_10855	COG0723	plastoquinol--plastocyanin reductase activity
NMH04_10865	COG5582	Belongs to the UPF0302 family
NMH04_10870	COG0457	Tetratricopeptide repeat
NMH04_10875	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NMH04_10880	COG0287	Prephenate dehydrogenase
NMH04_10885	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NMH04_10890	COG0159	tryptophan synthase activity
NMH04_10895	COG0133	tryptophan synthase activity
NMH04_10905	COG0134	indole-3-glycerol-phosphate synthase activity
NMH04_10910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NMH04_10920	COG4401	Chorismate mutase type I
NMH04_10925	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NMH04_10930	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NMH04_10935	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NMH04_10940	COG0105	UTP biosynthetic process
NMH04_10945	COG0142	geranyltranstransferase activity
NMH04_10950	COG2226	methyltransferase
NMH04_10955	COG0142	geranyltranstransferase activity
NMH04_10965	COG0302	gtp cyclohydrolase
NMH04_10970	COG0776	regulation of translation
NMH04_10975	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NMH04_10990	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NMH04_10995	COG1160	GTP binding
NMH04_11020	COG1304	FMN binding
NMH04_11025	COG0539	negative regulation of cytoplasmic translation
NMH04_11030	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NMH04_11040	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
NMH04_11045	COG2959	enzyme of heme biosynthesis
NMH04_11050	COG3409	Peptidoglycan-binding domain 1 protein
NMH04_11050	COG3773	Cell wall hydrolase
NMH04_11055	COG2339	peptidase activity
NMH04_11060	COG0492	ferredoxin-NADP+ reductase activity
NMH04_11065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NMH04_11070	COG4862	establishment of competence for transformation
NMH04_11075	COG1408	metallophosphoesterase
NMH04_11085	COG1388	LysM domain
NMH04_11090	COG1266	CAAX protease self-immunity
NMH04_11095	COG0514	ATP-dependent DNA helicase (RecQ)
NMH04_11100	COG4955	Helix-turn-helix domain
NMH04_11105	COG1141	Ferredoxin
NMH04_11110	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NMH04_11115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NMH04_11130	COG1595	DNA-templated transcription, initiation
NMH04_11135	COG5002	protein histidine kinase activity
NMH04_11140	COG0745	RESPONSE REGULATOR receiver
NMH04_11145	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NMH04_11150	COG1333	cytochrome c biogenesis protein
NMH04_11155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NMH04_11160	COG1187	pseudouridine synthase activity
NMH04_11165	COG0700	Nucleoside recognition
NMH04_11170	COG2715	membrane protein required for spore maturation
NMH04_11175	COG1686	Belongs to the peptidase S11 family
NMH04_11190	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NMH04_11195	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NMH04_11205	COG1547	Domain of unknown function (DUF309)
NMH04_11210	COG0456	acetyltransferase
NMH04_11215	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NMH04_11225	COG0307	riboflavin synthase, alpha
NMH04_11245	COG2814	Major facilitator Superfamily
NMH04_11250	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NMH04_11255	COG4086	secreted protein
NMH04_11260	COG0019	diaminopimelate decarboxylase activity
NMH04_11265	COG0697	spore germination
NMH04_11280	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NMH04_11300	COG1191	sigma factor activity
NMH04_11305	COG2172	sigma factor antagonist activity
NMH04_11315	COG1686	Belongs to the peptidase S11 family
NMH04_11320	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NMH04_11325	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NMH04_11330	COG4974	Belongs to the 'phage' integrase family
NMH04_11340	COG0735	belongs to the Fur family
NMH04_11345	COG1300	Membrane
NMH04_11350	COG1404	Belongs to the peptidase S8 family
NMH04_11360	COG2153	protein acetylation
NMH04_11365	COG1379	DNA repair
NMH04_11370	COG0494	nUDIX hydrolase
NMH04_11375	COG0667	Aldo Keto reductase
NMH04_11385	COG1073	alpha beta
NMH04_11390	COG0457	Tetratricopeptide repeat
NMH04_11400	COG4918	Iron-sulphur cluster biosynthesis
NMH04_11405	COG4305	rare lipoprotein A
NMH04_11410	COG0456	acetyltransferase
NMH04_11410	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NMH04_11415	COG0456	acetyltransferase
NMH04_11425	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NMH04_11435	COG2211	Major facilitator Superfamily
NMH04_11440	COG1072	(Pantothenic acid kinase))
NMH04_11445	COG0446	pyridine nucleotide-disulphide oxidoreductase
NMH04_11455	COG0300	oxidoreductase activity
NMH04_11460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NMH04_11465	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NMH04_11485	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NMH04_11490	COG4187	Peptidase family M20/M25/M40
NMH04_11495	COG1902	pentaerythritol trinitrate reductase activity
NMH04_11500	COG0596	Alpha beta hydrolase
NMH04_11505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NMH04_11515	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NMH04_11520	COG2188	Transcriptional regulator
NMH04_11525	COG2723	6-phospho-beta-galactosidase activity
NMH04_11530	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NMH04_11535	COG1447	Phosphotransferase system cellobiose-specific component IIA
NMH04_11540	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NMH04_11550	COG1028	Short-chain dehydrogenase reductase Sdr
NMH04_11560	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NMH04_11565	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NMH04_11575	COG0706	membrane insertase activity
NMH04_11580	COG0835	chemotaxis
NMH04_11585	COG2195	Cleaves the N-terminal amino acid of tripeptides
NMH04_11590	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NMH04_11595	COG0346	lactoylglutathione lyase activity
NMH04_11605	COG1376	ErfK ybiS ycfS ynhG family protein
NMH04_11610	COG4129	membrane
NMH04_11615	COG1126	abc transporter atp-binding protein
NMH04_11620	COG0765	amino acid transport
NMH04_11625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NMH04_11635	COG1597	lipid kinase activity
NMH04_11645	COG0508	dehydrogenase complex catalyzes the overall conversion of
NMH04_11650	COG0022	dehydrogenase e1 component
NMH04_11655	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NMH04_11660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NMH04_11665	COG3426	butyrate kinase activity
NMH04_11670	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NMH04_11675	COG0280	phosphate acetyltransferase
NMH04_11680	COG3290	protein histidine kinase activity
NMH04_11680	COG3829	transcription factor binding
NMH04_11690	COG0584	glycerophosphoryl diester phosphodiesterase
NMH04_11695	COG0457	Tetratricopeptide repeat
NMH04_11705	COG0750	zinc metalloprotease
NMH04_11710	COG0497	DNA recombination
NMH04_11715	COG1438	arginine binding
NMH04_11720	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
NMH04_11725	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NMH04_11730	COG0142	geranyltranstransferase activity
NMH04_11735	COG1722	exodeoxyribonuclease VII activity
NMH04_11740	COG1570	exodeoxyribonuclease VII activity
NMH04_11745	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NMH04_11750	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NMH04_11755	COG1302	Protein conserved in bacteria
NMH04_11760	COG0439	Biotin carboxylase
NMH04_11765	COG0511	ligase activity, forming carbon-carbon bonds
NMH04_11805	COG3854	ATPases associated with a variety of cellular activities
NMH04_11815	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NMH04_11820	COG0006	proline dipeptidase activity
NMH04_11825	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NMH04_11835	COG3872	metal-dependent enzyme
NMH04_11845	COG1752	Esterase of the alpha-beta hydrolase superfamily
NMH04_11850	COG1321	iron dependent repressor
NMH04_11855	COG0095	Lipoate-protein ligase
NMH04_11860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NMH04_11865	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NMH04_11870	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NMH04_11875	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NMH04_11880	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NMH04_11905	COG0681	Belongs to the peptidase S26 family
NMH04_11940	COG4970	Tfp pilus assembly protein FimT
NMH04_11945	COG4537	Required for transformation and DNA binding
NMH04_11950	COG1459	type II secretion system
NMH04_11955	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NMH04_11960	COG1366	Belongs to the anti-sigma-factor antagonist family
NMH04_11970	COG1393	Belongs to the ArsC family
NMH04_11980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NMH04_11995	COG0011	TIGRFAM Protein of
NMH04_12000	COG2814	Major facilitator Superfamily
NMH04_12005	COG2866	Carboxypeptidase
NMH04_12010	COG1368	sulfuric ester hydrolase activity
NMH04_12015	COG1940	carbohydrate kinase activity
NMH04_12020	COG4483	Protein conserved in bacteria
NMH04_12025	COG0457	Tetratricopeptide repeat
NMH04_12025	COG0705	Rhomboid family
NMH04_12040	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NMH04_12045	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NMH04_12055	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NMH04_12060	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NMH04_12065	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NMH04_12070	COG0581	inorganic phosphate transmembrane transporter activity
NMH04_12075	COG0573	inorganic phosphate transmembrane transporter activity
NMH04_12080	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NMH04_12085	COG0768	penicillin binding
NMH04_12090	COG0477	Major facilitator Superfamily
NMH04_12095	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NMH04_12100	COG2839	Protein conserved in bacteria
NMH04_12105	COG5521	maltodextrose utilization protein MalA
NMH04_12110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NMH04_12115	COG1388	LysM domain
NMH04_12120	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NMH04_12125	COG4709	membrane
NMH04_12130	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
NMH04_12135	COG1940	carbohydrate kinase activity
NMH04_12140	COG0735	belongs to the Fur family
NMH04_12145	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NMH04_12150	COG1121	(ABC) transporter
NMH04_12155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NMH04_12170	COG0513	Belongs to the DEAD box helicase family
NMH04_12180	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NMH04_12185	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NMH04_12190	COG2384	SAM-dependent methyltransferase
NMH04_12195	COG2010	Cytochrome c
NMH04_12200	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMH04_12205	COG0358	DNA primase activity
NMH04_12210	COG1671	Belongs to the UPF0178 family
NMH04_12215	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NMH04_12220	COG0517	IMP dehydrogenase activity
NMH04_12225	COG0751	glycine-tRNA ligase activity
NMH04_12230	COG0752	glycyl-tRNA synthetase alpha subunit
NMH04_12235	COG1381	Involved in DNA repair and RecF pathway recombination
NMH04_12245	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NMH04_12250	COG0295	cytidine deaminase activity
NMH04_12255	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NMH04_12260	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NMH04_12265	COG1480	7TM receptor with intracellular HD hydrolase
NMH04_12270	COG1702	phosphate starvation-inducible protein PhoH
NMH04_12275	COG0561	phosphatase activity
NMH04_12290	COG4864	UPF0365 protein
NMH04_12295	COG1030	water channel activity
NMH04_12300	COG1610	YqeY-like protein
NMH04_12310	COG1283	sodium-dependent phosphate transmembrane transporter activity
NMH04_12315	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NMH04_12320	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NMH04_12325	COG2264	protein methyltransferase activity
NMH04_12330	COG0484	heat shock protein binding
NMH04_12335	COG0443	Heat shock 70 kDa protein
NMH04_12340	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NMH04_12345	COG1420	regulation of RNA biosynthetic process
NMH04_12350	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NMH04_12355	COG0481	GTPase activity
NMH04_12365	COG0860	N-Acetylmuramoyl-L-alanine amidase
NMH04_12370	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NMH04_12375	COG0268	Binds directly to 16S ribosomal RNA
NMH04_12380	COG1466	dna polymerase III delta subunit
NMH04_12390	COG0658	competence protein
NMH04_12390	COG2333	competence protein COMEC
NMH04_12395	COG2131	deaminase
NMH04_12400	COG1596	polysaccharide export
NMH04_12400	COG1555	photosystem II stabilization
NMH04_12405	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NMH04_12410	COG2226	methyltransferase
NMH04_12415	COG0799	negative regulation of ribosome biogenesis
NMH04_12420	COG1713	HD superfamily hydrolase involved in NAD metabolism
NMH04_12425	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NMH04_12430	COG1534	Rna-binding protein
NMH04_12435	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NMH04_12440	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NMH04_12445	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
NMH04_12460	COG2755	lipolytic protein G-D-S-L family
NMH04_12470	COG0457	Tetratricopeptide repeat
NMH04_12495	COG0726	polysaccharide deacetylase
NMH04_12530	COG1131	(ABC) transporter
NMH04_12555	COG2160	L-arabinose isomerase activity
NMH04_12570	COG1609	Transcriptional regulator
NMH04_12580	COG1846	Transcriptional regulator
NMH04_12590	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NMH04_12595	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
NMH04_12600	COG1733	regulation of RNA biosynthetic process
NMH04_12605	COG0657	acetylesterase activity
NMH04_12660	COG1309	transcriptional regulator
NMH04_12670	COG2602	Beta-lactamase
NMH04_12675	COG1960	acyl-CoA dehydrogenase activity
NMH04_12680	COG1126	abc transporter atp-binding protein
NMH04_12685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NMH04_12690	COG0765	amino acid transport
NMH04_12700	COG3546	catalase activity
NMH04_12705	COG1063	alcohol dehydrogenase
NMH04_12715	COG1028	Short-chain dehydrogenase reductase Sdr
NMH04_12725	COG1115	amino acid carrier protein
NMH04_12730	COG0583	DNA-binding transcription factor activity
NMH04_12735	COG1063	alcohol dehydrogenase
NMH04_12740	COG2226	methyltransferase
NMH04_12765	COG0626	cystathionine gamma-synthase activity
NMH04_12770	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NMH04_12775	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NMH04_12780	COG2226	methyltransferase
NMH04_12795	COG0768	penicillin binding
NMH04_12800	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NMH04_12805	COG0572	uridine kinase
NMH04_12810	COG0826	peptidase U32
NMH04_12815	COG0826	peptidase U32
NMH04_12820	COG4122	O-methyltransferase activity
NMH04_12825	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NMH04_12830	COG0183	Belongs to the thiolase family
NMH04_12835	COG0318	PFAM AMP-dependent synthetase and ligase
NMH04_12840	COG1268	BioY protein
NMH04_12845	COG3906	Belongs to the UPF0473 family
NMH04_12850	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NMH04_12855	COG4472	Bacterial protein of unknown function (DUF965)
NMH04_12860	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NMH04_12865	COG0628	permease
NMH04_12870	COG1126	abc transporter atp-binding protein
NMH04_12875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NMH04_12880	COG0765	amino acid transport
NMH04_12885	COG0765	amino acid transport
NMH04_12900	COG3881	PFAM PRC-barrel domain
NMH04_12905	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NMH04_12910	COG0457	Tetratricopeptide repeat
NMH04_12915	COG0482	sulfurtransferase activity
NMH04_12920	COG1104	cysteine desulfurase activity
NMH04_12925	COG1959	2 iron, 2 sulfur cluster binding
NMH04_12930	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NMH04_12935	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NMH04_12950	COG0124	histidyl-tRNA synthetase
NMH04_12960	COG0860	N-Acetylmuramoyl-L-alanine amidase
NMH04_12960	COG3103	Sh3 type 3 domain protein
NMH04_12960	COG4991	sh3 domain protein
NMH04_12965	COG1490	D-aminoacyl-tRNA deacylase activity
NMH04_12970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NMH04_12975	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NMH04_12980	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NMH04_12980	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NMH04_12985	COG5416	Lipopolysaccharide assembly protein A domain
NMH04_12990	COG0490	domain, Protein
NMH04_12995	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NMH04_12995	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NMH04_13005	COG2244	polysaccharide biosynthetic process
NMH04_13010	COG2323	membrane
NMH04_13020	COG1862	Preprotein translocase
NMH04_13025	COG0343	queuine tRNA-ribosyltransferase activity
NMH04_13030	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NMH04_13040	COG2255	four-way junction helicase activity
NMH04_13045	COG0632	four-way junction helicase activity
NMH04_13055	COG2112	serine threonine protein kinase
NMH04_13070	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NMH04_13090	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NMH04_13095	COG0157	Belongs to the NadC ModD family
NMH04_13100	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NMH04_13105	COG1104	cysteine desulfurase activity
NMH04_13110	COG1827	regulation of RNA biosynthetic process
NMH04_13115	COG0077	Prephenate dehydratase
NMH04_13120	COG4492	Belongs to the UPF0735 family
NMH04_13125	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NMH04_13130	COG3290	protein histidine kinase activity
NMH04_13135	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NMH04_13140	COG2868	ribosomal protein
NMH04_13145	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NMH04_13150	COG1994	Peptidase M50
NMH04_13155	COG0739	heme binding
NMH04_13160	COG2894	cell division
NMH04_13165	COG0850	regulation of cytokinetic process
NMH04_13170	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NMH04_13180	COG1077	Cell shape determining protein MreB Mrl
NMH04_13185	COG2003	Belongs to the UPF0758 family
NMH04_13190	COG0424	maF-like protein
NMH04_13205	COG0285	dihydrofolate synthase activity
NMH04_13210	COG0525	valine-tRNA ligase activity
NMH04_13220	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NMH04_13225	COG1388	LysM domain
NMH04_13230	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NMH04_13235	COG0113	porphobilinogen synthase activity
NMH04_13240	COG1587	Uroporphyrinogen-III synthase
NMH04_13245	COG0181	hydroxymethylbilane synthase activity
NMH04_13250	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NMH04_13255	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NMH04_13280	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NMH04_13285	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NMH04_13290	COG0470	DNA polymerase III
NMH04_13290	COG1067	ATP-dependent peptidase activity
NMH04_13295	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NMH04_13300	COG0544	peptidyl-prolyl cis-trans isomerase activity
NMH04_13305	COG1477	protein flavinylation
NMH04_13305	COG0457	Tetratricopeptide repeat
NMH04_13310	COG0066	3-isopropylmalate dehydratase activity
NMH04_13315	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NMH04_13320	COG0473	3-isopropylmalate dehydrogenase activity
NMH04_13325	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NMH04_13330	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NMH04_13335	COG0440	acetolactate synthase activity
NMH04_13340	COG0028	Belongs to the TPP enzyme family
NMH04_13345	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NMH04_13350	COG2706	6-phosphogluconolactonase activity
NMH04_13355	COG3339	Conserved Protein
NMH04_13360	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NMH04_13365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NMH04_13370	COG1696	Membrane protein involved in D-alanine export
NMH04_13375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NMH04_13410	COG0622	Phosphoesterase
NMH04_13415	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NMH04_13420	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NMH04_13425	COG5401	PFAM Sporulation and spore germination
NMH04_13430	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NMH04_13435	COG1846	Transcriptional regulator
NMH04_13440	COG2197	response regulator
NMH04_13445	COG2851	Citrate transporter
NMH04_13450	COG0583	DNA-binding transcription factor activity
NMH04_13455	COG2828	Protein conserved in bacteria
NMH04_13465	COG0824	Thioesterase
NMH04_13470	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NMH04_13475	COG1053	succinate dehydrogenase
NMH04_13480	COG2009	succinate dehydrogenase
NMH04_13485	COG1719	4-vinyl reductase, 4VR
NMH04_13490	COG0527	aspartate kinase activity
NMH04_13495	COG0322	excinuclease ABC activity
NMH04_13500	COG3118	belongs to the thioredoxin family
NMH04_13505	COG3534	alpha-L-arabinofuranosidase
NMH04_13510	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NMH04_13515	COG2086	electron transfer activity
NMH04_13520	COG1024	Enoyl-CoA hydratase
NMH04_13525	COG1309	transcriptional regulator
NMH04_13530	COG0318	PFAM AMP-dependent synthetase and ligase
NMH04_13540	COG3766	membrane
NMH04_13545	COG1193	negative regulation of DNA recombination
NMH04_13550	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NMH04_13550	COG1796	DNA polymerase
NMH04_13555	COG1286	toxin biosynthetic process
NMH04_13560	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NMH04_13565	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NMH04_13570	COG0072	phenylalanine-tRNA ligase activity
NMH04_13570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NMH04_13575	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NMH04_13580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NMH04_13590	COG1966	Carbon starvation protein
NMH04_13595	COG1363	Peptidase, m42
NMH04_13605	COG3326	Membrane
NMH04_13610	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NMH04_13615	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NMH04_13620	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NMH04_13625	COG1346	cytolysis
NMH04_13635	COG3279	Response regulator of the LytR AlgR family
NMH04_13640	COG3275	phosphorelay sensor kinase activity
NMH04_13645	COG1011	Hydrolase
NMH04_13655	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NMH04_13665	COG0398	Pfam SNARE associated Golgi protein
NMH04_13670	COG1484	DNA-dependent DNA replication
NMH04_13675	COG3611	Membrane attachment protein
NMH04_13680	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NMH04_13690	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NMH04_13695	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NMH04_13700	COG0237	dephospho-CoA kinase activity
NMH04_13705	COG1971	Probably functions as a manganese efflux pump
NMH04_13710	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NMH04_13715	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NMH04_13715	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NMH04_13720	COG5002	protein histidine kinase activity
NMH04_13725	COG0745	RESPONSE REGULATOR receiver
NMH04_13730	COG0039	L-malate dehydrogenase activity
NMH04_13735	COG0538	isocitrate dehydrogenase activity
NMH04_13740	COG0372	Belongs to the citrate synthase family
NMH04_13745	COG2707	UPF0756 membrane protein
NMH04_13750	COG0628	permease
NMH04_13755	COG3030	protein affecting phage T7 exclusion by the F plasmid
NMH04_13765	COG0205	6-phosphofructokinase activity
NMH04_13770	COG0825	malonyl-CoA metabolic process
NMH04_13775	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NMH04_13780	COG0281	malic enzyme
NMH04_13785	COG0587	DNA-directed DNA polymerase activity
NMH04_13805	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NMH04_13815	COG4109	DRTGG domain
NMH04_13820	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NMH04_13825	COG1028	Short-chain dehydrogenase reductase Sdr
NMH04_13835	COG0165	Argininosuccinate lyase
NMH04_13840	COG0137	argininosuccinate synthase activity
NMH04_13845	COG0521	Mo-molybdopterin cofactor biosynthetic process
NMH04_13850	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NMH04_13855	COG0827	DNA restriction-modification system
NMH04_13860	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NMH04_13865	COG3874	Sporulation protein YtfJ
NMH04_13875	COG1714	RDD family
NMH04_13880	COG0616	signal peptide processing
NMH04_13885	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NMH04_13895	COG3239	Fatty acid desaturase
NMH04_13900	COG4585	Histidine kinase
NMH04_13905	COG2197	response regulator
NMH04_13910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NMH04_13915	COG0745	RESPONSE REGULATOR receiver
NMH04_13920	COG2205	protein histidine kinase activity
NMH04_13925	COG0772	Belongs to the SEDS family
NMH04_13930	COG1695	Transcriptional regulator
NMH04_13935	COG1136	(ABC) transporter
NMH04_13940	COG0577	efflux transmembrane transporter activity
NMH04_13945	COG0402	S-adenosylhomocysteine deaminase activity
NMH04_13950	COG2249	NAD(P)H dehydrogenase (quinone) activity
NMH04_13970	COG1279	arginine transmembrane transporter activity
NMH04_13990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NMH04_14000	COG0301	tRNA thio-modification
NMH04_14005	COG1104	cysteine desulfurase activity
NMH04_14010	COG1114	Component of the transport system for branched-chain amino acids
NMH04_14015	COG1114	Component of the transport system for branched-chain amino acids
NMH04_14020	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NMH04_14025	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NMH04_14030	COG1309	transcriptional regulator
NMH04_14035	COG1956	GAF domain-containing protein
NMH04_14040	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NMH04_14055	COG1335	isochorismatase
NMH04_14065	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NMH04_14070	COG2329	Antibiotic biosynthesis monooxygenase
NMH04_14075	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NMH04_14080	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NMH04_14085	COG0454	-acetyltransferase
NMH04_14090	COG0517	IMP dehydrogenase activity
NMH04_14095	COG0123	including yeast histone deacetylase and acetoin utilization protein
NMH04_14100	COG1609	Transcriptional regulator
NMH04_14105	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NMH04_14105	COG1605	Chorismate mutase
NMH04_14110	COG3118	belongs to the thioredoxin family
NMH04_14115	COG4980	gas vesicle protein
NMH04_14120	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NMH04_14125	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NMH04_14130	COG1674	ftsk spoiiie
NMH04_14135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NMH04_14140	COG4848	Belongs to the UPF0354 family
NMH04_14145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NMH04_14160	COG1363	Peptidase, m42
NMH04_14165	COG5584	Small secreted protein
NMH04_14170	COG0281	malic enzyme
NMH04_14175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NMH04_14180	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NMH04_14190	COG0510	thiamine kinase activity
NMH04_14195	COG1597	lipid kinase activity
NMH04_14205	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NMH04_14210	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NMH04_14215	COG3340	Belongs to the peptidase S51 family
NMH04_14220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NMH04_14225	COG2252	PERMEase
NMH04_14230	COG1349	DNA-binding transcription factor activity
NMH04_14235	COG1187	pseudouridine synthase activity
NMH04_14240	COG2244	polysaccharide biosynthetic process
NMH04_14245	COG2081	HI0933 family
NMH04_14255	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NMH04_14260	COG3196	Protein conserved in bacteria
NMH04_14270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NMH04_14275	COG5578	integral membrane protein
NMH04_14280	COG0673	inositol 2-dehydrogenase activity
NMH04_14285	COG1653	transport
NMH04_14290	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NMH04_14295	COG4209	transmembrane transport
NMH04_14300	COG2207	Transcriptional regulator
NMH04_14305	COG1733	regulation of RNA biosynthetic process
NMH04_14310	COG2814	Major facilitator Superfamily
NMH04_14315	COG0656	L-ascorbic acid biosynthetic process
NMH04_14320	COG1653	transport
NMH04_14325	COG0395	ABC-type sugar transport system, permease component
NMH04_14330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NMH04_14335	COG1073	alpha beta
NMH04_14340	COG0495	leucyl-tRNA aminoacylation
NMH04_14360	COG2433	Pfam Transposase IS66
NMH04_14365	COG0577	efflux transmembrane transporter activity
NMH04_14370	COG1136	(ABC) transporter
NMH04_14380	COG1131	(ABC) transporter
NMH04_14385	COG1725	Transcriptional regulator
NMH04_14405	COG1242	4 iron, 4 sulfur cluster binding
NMH04_14410	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NMH04_14415	COG4326	sporulation control protein
NMH04_14425	COG2267	carboxylic ester hydrolase activity
NMH04_14430	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NMH04_14435	COG0367	asparagine synthase
NMH04_14440	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NMH04_14445	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NMH04_14455	COG1506	peptidase
NMH04_14460	COG1233	COG1233 Phytoene dehydrogenase and related
NMH04_14480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NMH04_14485	COG1116	anion transmembrane transporter activity
NMH04_14490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NMH04_14495	COG0494	nUDIX hydrolase
NMH04_14500	COG2310	stress, protein
NMH04_14515	COG4824	toxin secretion phage lysis holin
NMH04_14525	COG0783	Belongs to the Dps family
NMH04_14540	COG1854	S-ribosylhomocysteine lyase activity
NMH04_14545	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NMH04_14550	COG0288	reversible hydration of carbon dioxide
NMH04_14555	COG0803	Belongs to the bacterial solute-binding protein 9 family
NMH04_14555	COG3443	Belongs to the bacterial solute-binding protein 9 family
NMH04_14565	COG1271	oxidase subunit
NMH04_14570	COG1294	oxidase, subunit
NMH04_14585	COG4948	Mandelate Racemase Muconate Lactonizing
NMH04_14590	COG0318	PFAM AMP-dependent synthetase and ligase
NMH04_14595	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NMH04_14600	COG0596	Alpha beta hydrolase
NMH04_14605	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NMH04_14610	COG1169	isochorismate synthase
NMH04_14615	COG1575	Belongs to the MenA family. Type 1 subfamily
NMH04_14620	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NMH04_14750	COG3859	Proton-coupled thiamine transporter YuaJ
NMH04_14755	COG1247	-acetyltransferase
NMH04_14760	COG3339	Conserved Protein
NMH04_14765	COG0772	Belongs to the SEDS family
NMH04_14770	COG0772	Belongs to the SEDS family
NMH04_14775	COG2268	Band 7 protein
NMH04_14780	COG1585	Membrane protein implicated in regulation of membrane protease activity
NMH04_14785	COG2318	DinB family
NMH04_14790	COG1454	alcohol dehydrogenase
NMH04_14795	COG1012	belongs to the aldehyde dehydrogenase family
NMH04_14800	COG1510	regulation of RNA biosynthetic process
NMH04_14815	COG3409	Peptidoglycan-binding domain 1 protein
NMH04_14815	COG5632	N-Acetylmuramoyl-L-alanine amidase
NMH04_14870	COG3778	Protein conserved in bacteria
NMH04_14875	COG3299	homolog of phage Mu protein gp47
NMH04_14880	COG3628	GPW Gp25 family protein
NMH04_14890	COG4193	domain, Protein
NMH04_14895	COG1652	LysM domain
NMH04_14900	COG3953	SLT domain
NMH04_14900	COG3953	SLT domain
NMH04_14900	COG5280	Phage tail tape measure protein TP901
NMH04_14900	COG5280	Phage tail tape measure protein TP901
NMH04_14955	COG4653	Phage capsid family
NMH04_14960	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NMH04_14965	COG5518	Phage portal protein
NMH04_14970	COG1783	phage Terminase large subunit
NMH04_14975	COG5484	DNA packaging
NMH04_14980	COG1595	DNA-templated transcription, initiation
NMH04_14990	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
NMH04_15010	COG1396	sequence-specific DNA binding
NMH04_15020	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NMH04_15035	COG0628	permease
NMH04_15045	COG0673	inositol 2-dehydrogenase activity
NMH04_15050	COG0693	protein deglycase activity
NMH04_15055	COG0840	transmembrane signaling receptor activity
NMH04_15060	COG0840	transmembrane signaling receptor activity
NMH04_15065	COG0840	transmembrane signaling receptor activity
NMH04_15070	COG0840	transmembrane signaling receptor activity
NMH04_15085	COG2070	2-Nitropropane dioxygenase
NMH04_15090	COG0432	Pfam Uncharacterised protein family UPF0047
NMH04_15095	COG1253	flavin adenine dinucleotide binding
NMH04_15100	COG2738	Putative neutral zinc metallopeptidase
NMH04_15110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NMH04_15125	COG0166	Belongs to the GPI family
NMH04_15130	COG1979	alcohol dehydrogenase
NMH04_15135	COG1979	alcohol dehydrogenase
NMH04_15140	COG2155	Conserved Protein
NMH04_15145	COG1098	S1 RNA binding domain
NMH04_15150	COG0436	Aminotransferase
NMH04_15155	COG1522	sequence-specific DNA binding
NMH04_15160	COG2267	carboxylic ester hydrolase activity
NMH04_15170	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NMH04_15175	COG2205	protein histidine kinase activity
NMH04_15190	COG5018	Exonuclease
NMH04_15195	COG2814	Major facilitator Superfamily
NMH04_15200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NMH04_15205	COG3011	Protein conserved in bacteria
NMH04_15215	COG3290	protein histidine kinase activity
NMH04_15220	COG4565	transcriptional regulatory protein
NMH04_15225	COG1744	ABC transporter substrate-binding protein PnrA-like
NMH04_15230	COG3845	ABC transporter
NMH04_15235	COG4603	Belongs to the binding-protein-dependent transport system permease family
NMH04_15240	COG1079	Belongs to the binding-protein-dependent transport system permease family
NMH04_15245	COG3493	citrate carrier protein
NMH04_15255	COG2111	Na H antiporter
NMH04_15255	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NMH04_15260	COG2111	Na H antiporter
NMH04_15265	COG1006	Multisubunit Na H antiporter MnhC subunit
NMH04_15270	COG0651	ATP synthesis coupled electron transport
NMH04_15275	COG1863	multisubunit Na H antiporter MnhE subunit
NMH04_15280	COG2212	antiporter activity
NMH04_15285	COG1320	monovalent cation:proton antiporter activity
NMH04_15290	COG2050	protein possibly involved in aromatic compounds catabolism
NMH04_15295	COG2197	response regulator
NMH04_15300	COG4585	Histidine kinase
NMH04_15310	COG0142	geranyltranstransferase activity
NMH04_15325	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
NMH04_15330	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NMH04_15335	COG1335	isochorismatase
NMH04_15340	COG5506	Protein of unknown function (DUF1694)
NMH04_15360	COG0628	permease
NMH04_15375	COG1418	mRNA catabolic process
NMH04_15380	COG1028	Short-chain dehydrogenase reductase Sdr
NMH04_15390	COG1511	domain protein
NMH04_15395	COG1674	ftsk spoiiie
NMH04_15395	COG0433	COG0433 Predicted ATPase
NMH04_15400	COG4499	WXG100 protein secretion system (Wss), protein YukC
NMH04_15405	COG5417	Belongs to the EsaB family
NMH04_15410	COG4842	Belongs to the WXG100 family
NMH04_15415	COG2508	Transcriptional regulator
NMH04_15415	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NMH04_15420	COG0686	Belongs to the AlaDH PNT family
NMH04_15425	COG1268	BioY protein
NMH04_15430	COG2056	Na+-H+ antiporter family
NMH04_15435	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NMH04_15440	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
NMH04_15445	COG3584	3D domain protein
NMH04_15460	COG1252	NADH dehydrogenase
NMH04_15465	COG0492	ferredoxin-NADP+ reductase activity
NMH04_15480	COG0316	Belongs to the HesB IscA family
NMH04_15485	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NMH04_15490	COG4844	belongs to the
NMH04_15495	COG1252	NADH dehydrogenase
NMH04_15505	COG4837	Protein of unknown function (DUF1462)
NMH04_15515	COG0823	Involved in the tonB-independent uptake of proteins
NMH04_15515	COG1506	peptidase
NMH04_15515	COG4946	Tricorn protease homolog
NMH04_15520	COG0083	homoserine kinase activity
NMH04_15525	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NMH04_15530	COG0460	homoserine dehydrogenase
NMH04_15535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NMH04_15540	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NMH04_15545	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NMH04_15550	COG0647	UMP catabolic process
NMH04_15555	COG2445	Protein of unknown function DUF86
NMH04_15560	COG4470	Protein conserved in bacteria
NMH04_15570	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NMH04_15575	COG0739	heme binding
NMH04_15595	COG3377	Domain of unknown function (DUF1805)
NMH04_15600	COG0737	Belongs to the 5'-nucleotidase family
NMH04_15605	COG1801	Protein of unknown function DUF72
NMH04_15610	COG2508	Transcriptional regulator
NMH04_15615	COG2140	Oxalate decarboxylase
NMH04_15620	COG2814	Major facilitator Superfamily
NMH04_15625	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NMH04_15630	COG2356	endonuclease I
NMH04_15645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMH04_15650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMH04_15655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NMH04_15675	COG0642	Histidine kinase
NMH04_15675	COG5002	protein histidine kinase activity
NMH04_15680	COG0745	RESPONSE REGULATOR receiver
NMH04_15685	COG2311	Membrane
NMH04_15695	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NMH04_15700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NMH04_15705	COG1309	transcriptional regulator
NMH04_15710	COG0719	Fe-S assembly protein
NMH04_15715	COG0822	iron-sulfur transferase activity
NMH04_15720	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NMH04_15725	COG0719	Fe-S assembly protein
NMH04_15730	COG0396	ATPase activity
NMH04_15740	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NMH04_15745	COG1464	Belongs to the NlpA lipoprotein family
NMH04_15750	COG2011	ABC-type metal ion transport system permease component
NMH04_15755	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NMH04_15765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NMH04_15770	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NMH04_15780	COG0509	glycine decarboxylation via glycine cleavage system
NMH04_15785	COG1393	Belongs to the ArsC family
NMH04_15790	COG1960	acyl-CoA dehydrogenase activity
NMH04_15795	COG0183	Belongs to the thiolase family
NMH04_15800	COG1024	Enoyl-CoA hydratase
NMH04_15800	COG1250	3-hydroxyacyl-CoA dehydrogenase
NMH04_15815	COG5577	PFAM Coat F domain
NMH04_15825	COG1120	ATPase activity
NMH04_15835	COG1028	Short-chain dehydrogenase reductase Sdr
NMH04_15840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NMH04_15845	COG0745	RESPONSE REGULATOR receiver
NMH04_15850	COG2205	protein histidine kinase activity
NMH04_15850	COG2770	Histidine kinase
NMH04_15860	COG1309	transcriptional regulator
NMH04_15865	COG0114	fumarate hydratase activity
NMH04_15875	COG0697	spore germination
NMH04_15880	COG0814	amino acid
NMH04_15895	COG2197	response regulator
NMH04_15900	COG4585	Histidine kinase
NMH04_15905	COG4758	membrane
NMH04_15915	COG1842	Phage shock protein A
NMH04_15920	COG4758	membrane
NMH04_15925	COG2096	Adenosyltransferase
NMH04_15930	COG1120	ATPase activity
NMH04_15935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMH04_15940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NMH04_15950	COG2721	sulfolactate sulfo-lyase activity
NMH04_15955	COG0246	Mannitol dehydrogenase
NMH04_15960	COG1609	Transcriptional regulator
NMH04_15965	COG1904	glucuronate isomerase
NMH04_15970	COG2205	protein histidine kinase activity
NMH04_15975	COG0745	RESPONSE REGULATOR receiver
NMH04_15980	COG1120	ATPase activity
NMH04_15985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMH04_15990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMH04_15995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NMH04_16000	COG0531	amino acid
NMH04_16015	COG1988	membrane-bound metal-dependent
NMH04_16020	COG1368	sulfuric ester hydrolase activity
NMH04_16025	COG0725	ABC transporter, periplasmic molybdate-binding protein
NMH04_16030	COG4149	molybdate abc transporter
NMH04_16035	COG0656	L-ascorbic acid biosynthetic process
NMH04_16040	COG1940	carbohydrate kinase activity
NMH04_16045	COG0025	NhaP-type Na H and K H
NMH04_16050	COG2860	membrane
NMH04_16055	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NMH04_16060	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NMH04_16065	COG2217	Heavy metal translocating P-type atpase
NMH04_16070	COG1121	(ABC) transporter
NMH04_16075	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NMH04_16080	COG0803	Belongs to the bacterial solute-binding protein 9 family
NMH04_16090	COG3226	Transcriptional regulator
NMH04_16095	COG0784	Response regulator, receiver
NMH04_16100	COG4191	Histidine kinase
NMH04_16105	COG1027	Aspartate ammonia-lyase
NMH04_16120	COG2217	Heavy metal translocating P-type atpase
NMH04_16125	COG2608	mercury ion transmembrane transporter activity
NMH04_16130	COG1937	Protein conserved in bacteria
NMH04_16150	COG0463	Glycosyl transferase, family 2
NMH04_16150	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NMH04_16160	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NMH04_16165	COG0557	exoribonuclease II activity
NMH04_16170	COG1647	Serine aminopeptidase, S33
NMH04_16175	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NMH04_16180	COG2002	toxin-antitoxin pair type II binding
NMH04_16185	COG1476	TRANSCRIPTIONal
NMH04_16190	COG1396	sequence-specific DNA binding
NMH04_16195	COG1396	sequence-specific DNA binding
NMH04_16200	COG1733	regulation of RNA biosynthetic process
NMH04_16205	COG1174	glycine betaine transport
NMH04_16210	COG1732	Glycine betaine
NMH04_16215	COG1174	glycine betaine transport
NMH04_16220	COG1125	glycine betaine transport
NMH04_16220	COG0517	IMP dehydrogenase activity
NMH04_16225	COG1510	regulation of RNA biosynthetic process
NMH04_16230	COG2095	MarC family integral membrane protein
NMH04_16240	COG0456	acetyltransferase
NMH04_16260	COG1131	(ABC) transporter
NMH04_16270	COG0148	phosphopyruvate hydratase activity
NMH04_16275	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NMH04_16280	COG0149	triose-phosphate isomerase activity
NMH04_16285	COG0126	phosphoglycerate kinase activity
NMH04_16290	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NMH04_16295	COG2390	Transcriptional regulator
NMH04_16300	COG0833	amino acid
NMH04_16305	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NMH04_16310	COG3829	transcription factor binding
NMH04_16315	COG2186	Transcriptional regulator
NMH04_16320	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NMH04_16330	COG0534	Mate efflux family protein
NMH04_16335	COG4608	Belongs to the ABC transporter superfamily
NMH04_16340	COG0444	Belongs to the ABC transporter superfamily
NMH04_16345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMH04_16350	COG0601	transmembrane transport
NMH04_16355	COG0747	negative chemotaxis
NMH04_16360	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NMH04_16365	COG0110	maltose O-acetyltransferase activity
NMH04_16370	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NMH04_16375	COG2244	polysaccharide biosynthetic process
NMH04_16380	COG5039	Polysaccharide pyruvyl transferase
NMH04_16385	COG1216	Glycosyl transferase, family 2
NMH04_16395	COG0438	transferase activity, transferring glycosyl groups
NMH04_16400	COG1215	transferase activity, transferring glycosyl groups
NMH04_16405	COG0438	transferase activity, transferring glycosyl groups
NMH04_16410	COG1086	Polysaccharide biosynthesis protein
NMH04_16415	COG0489	protein tyrosine kinase activity
NMH04_16420	COG3944	biosynthesis protein
NMH04_16425	COG1396	sequence-specific DNA binding
NMH04_16435	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NMH04_16440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMH04_16445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMH04_16450	COG0726	polysaccharide deacetylase
NMH04_16455	COG0488	(ABC) transporter
NMH04_16475	COG0601	transmembrane transport
NMH04_16480	COG0747	negative chemotaxis
NMH04_16485	COG1819	glycosyl
NMH04_16490	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NMH04_16505	COG0740	serine-type endopeptidase activity
NMH04_16510	COG1611	Belongs to the LOG family
NMH04_16515	COG1694	Mazg nucleotide pyrophosphohydrolase
NMH04_16520	COG0659	secondary active sulfate transmembrane transporter activity
NMH04_16525	COG0288	reversible hydration of carbon dioxide
NMH04_16530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NMH04_16540	COG1301	dicarboxylic acid transport
NMH04_16545	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NMH04_16550	COG1737	Transcriptional regulator
NMH04_16555	COG2162	N-hydroxyarylamine O-acetyltransferase activity
NMH04_16560	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NMH04_16565	COG1481	regulation of sporulation
NMH04_16570	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NMH04_16575	COG1660	Displays ATPase and GTPase activities
NMH04_16580	COG1051	belongs to the nudix hydrolase family
NMH04_16585	COG0492	ferredoxin-NADP+ reductase activity
NMH04_16590	COG0791	NLP P60 protein
NMH04_16590	COG3883	PFAM NLP P60 protein
NMH04_16595	COG0457	Tetratricopeptide repeat
NMH04_16600	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NMH04_16600	COG0140	phosphoribosyl-ATP diphosphatase activity
NMH04_16605	COG0107	imidazoleglycerol-phosphate synthase activity
NMH04_16610	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NMH04_16615	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NMH04_16620	COG0131	Imidazoleglycerol-phosphate dehydratase
NMH04_16625	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NMH04_16630	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NMH04_16635	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NMH04_16640	COG4990	cell redox homeostasis
NMH04_16645	COG2910	NAD(P)H-binding
NMH04_16650	COG1959	2 iron, 2 sulfur cluster binding
NMH04_16655	COG0110	maltose O-acetyltransferase activity
NMH04_16660	COG0546	phosphoglycolate phosphatase activity
NMH04_16665	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NMH04_16670	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NMH04_16675	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NMH04_16680	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NMH04_16685	COG0363	glucosamine-6-phosphate deaminase activity
NMH04_16690	COG2188	Transcriptional regulator
NMH04_16695	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NMH04_16700	COG1950	PFAM Membrane protein of
NMH04_16705	COG1983	PspC domain protein
NMH04_16710	COG3595	metallopeptidase activity
NMH04_16725	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NMH04_16735	COG4897	Protein conserved in bacteria
NMH04_16740	COG3848	Pyruvate phosphate dikinase
NMH04_16740	COG0574	Belongs to the PEP-utilizing enzyme family
NMH04_16745	COG1309	transcriptional regulator
NMH04_16750	COG2814	Major facilitator Superfamily
NMH04_16760	COG0745	RESPONSE REGULATOR receiver
NMH04_16765	COG5002	protein histidine kinase activity
NMH04_16770	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NMH04_16775	COG0463	Glycosyl transferase, family 2
NMH04_16780	COG1113	amino acid transport
NMH04_16785	COG0778	Nitroreductase
NMH04_16790	COG1733	regulation of RNA biosynthetic process
NMH04_16795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NMH04_16805	COG0793	Belongs to the peptidase S41A family
NMH04_16805	COG3409	Peptidoglycan-binding domain 1 protein
NMH04_16810	COG0730	response to heat
NMH04_16815	COG0791	NLP P60 protein
NMH04_16815	COG3883	PFAM NLP P60 protein
NMH04_16820	COG2177	Part of the ABC transporter FtsEX involved in
NMH04_16825	COG2884	Cell division ATP-binding protein ftsE
NMH04_16830	COG2010	Cytochrome c
NMH04_16835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NMH04_16855	COG0653	protein targeting
NMH04_16860	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NMH04_16865	COG0840	transmembrane signaling receptor activity
NMH04_16880	COG1516	flagellar protein fliS
NMH04_16885	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NMH04_16890	COG1334	flagellar protein FlaG
NMH04_16895	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NMH04_16900	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NMH04_16910	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NMH04_16915	COG4786	Flagellar basal body rod
NMH04_16915	COG1256	bacterial-type flagellum assembly
NMH04_16920	COG3418	PFAM FlgN family protein
NMH04_16935	COG1040	competence protein
NMH04_16945	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NMH04_16950	COG1307	EDD domain protein, DegV family
NMH04_16955	COG2197	response regulator
NMH04_16960	COG4585	Histidine kinase
NMH04_16965	COG1739	Uncharacterized protein family UPF0029
NMH04_16970	COG1316	TRANSCRIPTIONal
NMH04_16975	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NMH04_16980	COG0438	transferase activity, transferring glycosyl groups
NMH04_16985	COG1215	transferase activity, transferring glycosyl groups
NMH04_16990	COG3206	protein involved in exopolysaccharide biosynthesis
NMH04_16995	COG3307	-O-antigen
NMH04_17000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NMH04_17005	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NMH04_17010	COG0297	glycogen (starch) synthase activity
NMH04_17010	COG0438	transferase activity, transferring glycosyl groups
NMH04_17015	COG2244	polysaccharide biosynthetic process
NMH04_17030	COG0860	N-Acetylmuramoyl-L-alanine amidase
NMH04_17030	COG2247	cell wall binding repeat
NMH04_17035	COG0860	N-Acetylmuramoyl-L-alanine amidase
NMH04_17035	COG2247	cell wall binding repeat
NMH04_17040	COG2247	cell wall binding repeat
NMH04_17040	COG2385	sporulation resulting in formation of a cellular spore
NMH04_17050	COG1316	TRANSCRIPTIONal
NMH04_17055	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NMH04_17060	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NMH04_17065	COG1134	teichoic acid transport
NMH04_17070	COG1682	transport, permease protein
NMH04_17075	COG1216	Glycosyl transferase, family 2
NMH04_17110	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NMH04_17115	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
NMH04_17120	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NMH04_17125	COG4193	domain, Protein
NMH04_17135	COG1482	cell wall glycoprotein biosynthetic process
NMH04_17145	COG1175	transmembrane transport
NMH04_17150	COG1653	transport
NMH04_17155	COG2197	response regulator
NMH04_17160	COG2972	Histidine kinase
NMH04_17170	COG0454	-acetyltransferase
NMH04_17175	COG0800	Aldolase
NMH04_17180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NMH04_17185	COG1609	Transcriptional regulator
NMH04_17190	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NMH04_17195	COG1028	Short-chain dehydrogenase reductase Sdr
NMH04_17200	COG0697	spore germination
NMH04_17205	COG0814	amino acid
NMH04_17220	COG2814	Major facilitator Superfamily
NMH04_17225	COG1316	TRANSCRIPTIONal
NMH04_17230	COG0561	phosphatase activity
NMH04_17235	COG0791	NLP P60 protein
NMH04_17245	COG2843	Capsule synthesis protein
NMH04_17255	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NMH04_17260	COG0697	spore germination
NMH04_17275	COG1609	Transcriptional regulator
NMH04_17280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NMH04_17285	COG1869	D-ribose catabolic process
NMH04_17290	COG1129	ABC transporter
NMH04_17295	COG1172	Belongs to the binding-protein-dependent transport system permease family
NMH04_17300	COG1879	ABC-type sugar transport system periplasmic component
NMH04_17305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NMH04_17310	COG0583	DNA-binding transcription factor activity
NMH04_17315	COG0028	Belongs to the TPP enzyme family
NMH04_17320	COG3527	Alpha-acetolactate decarboxylase
NMH04_17325	COG1522	sequence-specific DNA binding
NMH04_17330	COG2059	Chromate
NMH04_17335	COG2059	Chromate
NMH04_17340	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NMH04_17350	COG4715	Zinc finger, swim domain protein
NMH04_17355	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NMH04_17360	COG2202	Pas domain
NMH04_17360	COG1366	Belongs to the anti-sigma-factor antagonist family
NMH04_17365	COG0561	phosphatase activity
NMH04_17380	COG1970	mechanosensitive ion channel activity
NMH04_17385	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NMH04_17390	COG0457	Tetratricopeptide repeat
NMH04_17395	COG4786	Flagellar basal body rod
NMH04_17400	COG4786	Flagellar basal body rod
NMH04_17405	COG1077	Cell shape determining protein MreB Mrl
NMH04_17410	COG1609	Transcriptional regulator
NMH04_17415	COG1846	Transcriptional regulator
NMH04_17420	COG2814	Major facilitator Superfamily
NMH04_17425	COG0671	phosphoesterase, PA-phosphatase related
NMH04_17430	COG0477	Major facilitator Superfamily
NMH04_17435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NMH04_17440	COG0765	amino acid transport
NMH04_17445	COG1126	abc transporter atp-binding protein
NMH04_17450	COG0004	ammonium transporteR
NMH04_17455	COG0347	Belongs to the P(II) protein family
NMH04_17460	COG0739	heme binding
NMH04_17465	COG1247	-acetyltransferase
NMH04_17475	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NMH04_17480	COG0523	cobalamin synthesis protein
NMH04_17485	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NMH04_17490	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NMH04_17495	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NMH04_17500	COG2223	nitrite transmembrane transporter activity
NMH04_17510	COG2304	oxidoreductase activity
NMH04_17515	COG2304	oxidoreductase activity
NMH04_17520	COG2385	sporulation resulting in formation of a cellular spore
NMH04_17525	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NMH04_17535	COG4836	Membrane
NMH04_17545	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NMH04_17550	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NMH04_17555	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NMH04_17560	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NMH04_17565	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NMH04_17570	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NMH04_17575	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NMH04_17580	COG0356	it plays a direct role in the translocation of protons across the membrane
NMH04_17590	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NMH04_17595	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NMH04_17600	COG4475	Protein of unknown function (DUF436)
NMH04_17605	COG0698	ribose 5-phosphate isomerase
NMH04_17610	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NMH04_17615	COG1971	Probably functions as a manganese efflux pump
NMH04_17620	COG0009	L-threonylcarbamoyladenylate synthase
NMH04_17625	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NMH04_17640	COG2890	protein-(glutamine-N5) methyltransferase activity
NMH04_17645	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NMH04_17650	COG0789	Transcriptional regulator
NMH04_17655	COG0679	Auxin Efflux Carrier
NMH04_17660	COG0281	malic enzyme
NMH04_17665	COG1435	thymidine kinase activity
NMH04_17670	COG0254	rRNA binding
NMH04_17675	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NMH04_17680	COG1494	fructose-1,6-bisphosphatase
NMH04_17685	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NMH04_17690	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NMH04_17695	COG0191	fructose-bisphosphate aldolase activity
NMH04_17700	COG2204	response regulator
NMH04_17705	COG4821	SIS domain
NMH04_17710	COG0504	CTP synthase activity
NMH04_17715	COG3343	RNA polymerase activity
NMH04_17730	COG1960	acyl-CoA dehydrogenase activity
NMH04_17735	COG1960	acyl-CoA dehydrogenase activity
NMH04_17740	COG1250	3-hydroxyacyl-CoA dehydrogenase
NMH04_17745	COG0183	Belongs to the thiolase family
NMH04_17750	COG0247	lactate metabolic process
NMH04_17750	COG2181	nitrate reductase activity
NMH04_17755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NMH04_17770	COG1619	proteins homologs of microcin C7 resistance protein MccF
NMH04_17775	COG1132	(ABC) transporter
NMH04_17780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NMH04_17785	COG1619	proteins homologs of microcin C7 resistance protein MccF
NMH04_17790	COG0018	arginyl-trna synthetase
NMH04_17795	COG4506	Protein conserved in bacteria
NMH04_17805	COG0010	Belongs to the arginase family
NMH04_17810	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NMH04_17815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NMH04_17825	COG1994	Peptidase M50
NMH04_17830	COG1942	4-Oxalocrotonate Tautomerase
NMH04_17840	COG3465	dGTPase activity
NMH04_17845	COG1078	dGTPase activity
NMH04_17850	COG4844	belongs to the
NMH04_17895	COG5444	nuclease activity
NMH04_17925	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NMH04_17935	COG0280	phosphate acetyltransferase
NMH04_17945	COG2814	Major facilitator Superfamily
NMH04_17950	COG1522	sequence-specific DNA binding
NMH04_17955	COG2814	Major facilitator Superfamily
NMH04_17960	COG0077	Prephenate dehydratase
NMH04_17965	COG1917	Cupin 2, conserved barrel domain protein
NMH04_17970	COG1028	Short-chain dehydrogenase reductase Sdr
NMH04_17975	COG0151	Belongs to the GarS family
NMH04_17980	COG0436	Aminotransferase
NMH04_17985	COG1028	Short-chain dehydrogenase reductase Sdr
NMH04_17990	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
NMH04_17995	COG1091	dTDP-4-dehydrorhamnose reductase activity
NMH04_18000	COG1088	dTDP-glucose 4,6-dehydratase activity
NMH04_18005	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NMH04_18010	COG3980	spore coat polysaccharide biosynthesis protein
NMH04_18015	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
NMH04_18020	COG2089	acid synthase
NMH04_18025	COG0456	acetyltransferase
NMH04_18030	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NMH04_18035	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NMH04_18040	COG0463	Glycosyl transferase, family 2
NMH04_18060	COG2363	Small membrane protein
NMH04_18065	COG2233	PERMEase
NMH04_18075	COG1012	belongs to the aldehyde dehydrogenase family
NMH04_18080	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NMH04_18085	COG1216	Glycosyl transferase, family 2
NMH04_18095	COG0351	phosphomethylpyrimidine kinase
NMH04_18125	COG1621	beta-fructofuranosidase activity
NMH04_18130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NMH04_18130	COG1263	PTS System
NMH04_18135	COG3711	transcriptional antiterminator
NMH04_18145	COG1404	Belongs to the peptidase S8 family
NMH04_18155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMH04_18160	COG0778	Nitroreductase
NMH04_18165	COG0772	Belongs to the SEDS family
NMH04_18175	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NMH04_18180	COG1845	cytochrome c oxidase, subunit III
NMH04_18185	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NMH04_18190	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NMH04_18200	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
NMH04_18205	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NMH04_18210	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NMH04_18225	COG2246	polysaccharide biosynthetic process
NMH04_18245	COG3162	membrane
NMH04_18250	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NMH04_18275	COG0352	thiamine-phosphate diphosphorylase activity
NMH04_18280	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NMH04_18285	COG0583	DNA-binding transcription factor activity
NMH04_18290	COG1380	Effector of murein hydrolase LrgA
NMH04_18295	COG1346	cytolysis
NMH04_18300	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NMH04_18305	COG0346	lactoylglutathione lyase activity
NMH04_18330	COG0765	amino acid transport
NMH04_18335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NMH04_18340	COG0457	Tetratricopeptide repeat
NMH04_18350	COG2357	RelA SpoT domain protein
NMH04_18355	COG1172	Belongs to the binding-protein-dependent transport system permease family
NMH04_18360	COG1129	ABC transporter
NMH04_18370	COG3420	alginic acid biosynthetic process
NMH04_18375	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NMH04_18385	COG1486	melibiose metabolic process
NMH04_18390	COG1447	Phosphotransferase system cellobiose-specific component IIA
NMH04_18395	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NMH04_18400	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NMH04_18405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NMH04_18405	COG3711	transcriptional antiterminator
NMH04_18425	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NMH04_18440	COG1595	DNA-templated transcription, initiation
NMH04_18450	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NMH04_18455	COG4988	ABC transporter
NMH04_18460	COG1294	oxidase, subunit
NMH04_18465	COG1271	oxidase subunit
NMH04_18480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMH04_18485	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NMH04_18490	COG4509	Sortase family
NMH04_18515	COG5386	Cell surface protein
NMH04_18520	COG5386	Cell surface protein
NMH04_18525	COG1733	regulation of RNA biosynthetic process
NMH04_18530	COG2514	catechol 2,3-dioxygenase activity
NMH04_18535	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NMH04_18535	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NMH04_18540	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NMH04_18540	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NMH04_18550	COG0726	polysaccharide deacetylase
NMH04_18555	COG1447	Phosphotransferase system cellobiose-specific component IIA
NMH04_18560	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NMH04_18565	COG2723	6-phospho-beta-galactosidase activity
NMH04_18570	COG1312	Catalyzes the dehydration of D-mannonate
NMH04_18575	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NMH04_18580	COG3711	transcriptional antiterminator
NMH04_18580	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NMH04_18605	COG1757	Na H antiporter
NMH04_18610	COG1027	Aspartate ammonia-lyase
NMH04_18615	COG0252	asparaginase activity
NMH04_18620	COG1396	sequence-specific DNA binding
NMH04_18645	COG4842	Belongs to the WXG100 family
NMH04_18650	COG2195	Cleaves the N-terminal amino acid of tripeptides
NMH04_18665	COG1737	Transcriptional regulator
NMH04_18670	COG2084	Dehydrogenase
NMH04_18680	COG2610	gluconate transmembrane transporter activity
NMH04_18685	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NMH04_18690	COG2850	peptidyl-arginine hydroxylation
NMH04_18705	COG2723	6-phospho-beta-galactosidase activity
NMH04_18710	COG1263	PTS System
NMH04_18710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NMH04_18710	COG2190	(PTS) system
NMH04_18715	COG3711	transcriptional antiterminator
NMH04_18720	COG3878	Protein conserved in bacteria
NMH04_18730	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NMH04_18735	COG1122	ATPase activity
NMH04_18740	COG4721	ABC-type cobalt transport system, permease component
NMH04_18745	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NMH04_18780	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NMH04_18785	COG0778	Nitroreductase
NMH04_18790	COG1846	Transcriptional regulator
NMH04_18795	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NMH04_18800	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NMH04_18805	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NMH04_18810	COG2390	Transcriptional regulator
NMH04_18820	COG2755	lipolytic protein G-D-S-L family
NMH04_18820	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NMH04_18825	COG0477	Major facilitator Superfamily
NMH04_18830	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NMH04_18835	COG2226	methyltransferase
NMH04_18845	COG0561	phosphatase activity
NMH04_18850	COG0789	Transcriptional regulator
NMH04_18855	COG0673	inositol 2-dehydrogenase activity
NMH04_18860	COG0840	transmembrane signaling receptor activity
NMH04_18865	COG1113	amino acid transport
NMH04_18870	COG4335	DNA alkylation repair
NMH04_18880	COG1070	Carbohydrate kinase
NMH04_18885	COG1737	Transcriptional regulator
NMH04_18930	COG0583	DNA-binding transcription factor activity
NMH04_18935	COG1609	Transcriptional regulator
NMH04_18940	COG2182	Extracellular solute-binding protein
NMH04_18945	COG1175	transmembrane transport
NMH04_18950	COG3833	ABC-type maltose transport systems, permease component
NMH04_18960	COG1874	Beta-galactosidase
NMH04_18995	COG2851	Citrate transporter
NMH04_19005	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NMH04_19010	COG1131	(ABC) transporter
NMH04_19015	COG2824	Alkylphosphonate utilization operon protein PhnA
NMH04_19020	COG1929	Belongs to the glycerate kinase type-1 family
NMH04_19025	COG2610	gluconate transmembrane transporter activity
NMH04_19030	COG3835	regulator
NMH04_19035	COG1309	transcriptional regulator
NMH04_19040	COG2814	Major facilitator Superfamily
NMH04_19050	COG1136	(ABC) transporter
NMH04_19055	COG0457	Tetratricopeptide repeat
NMH04_19060	COG3711	transcriptional antiterminator
NMH04_19065	COG2723	6-phospho-beta-galactosidase activity
NMH04_19070	COG2190	(PTS) system
NMH04_19070	COG1263	PTS System
NMH04_19070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NMH04_19095	COG0494	nUDIX hydrolase
NMH04_19110	COG1113	amino acid transport
NMH04_19115	COG1609	Transcriptional regulator
NMH04_19120	COG2814	Major facilitator Superfamily
NMH04_19125	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NMH04_19130	COG2814	Major facilitator Superfamily
NMH04_19150	COG5444	nuclease activity
NMH04_19165	COG2723	6-phospho-beta-galactosidase activity
NMH04_19170	COG1263	PTS System
NMH04_19170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NMH04_19170	COG2190	(PTS) system
NMH04_19175	COG2188	Transcriptional regulator
NMH04_19185	COG0384	phenazine biosynthesis protein PhzF
NMH04_19190	COG0583	DNA-binding transcription factor activity
NMH04_19210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NMH04_19225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NMH04_19240	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NMH04_19250	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NMH04_19260	COG4720	Psort location CytoplasmicMembrane, score
NMH04_19280	COG0456	acetyltransferase
NMH04_19285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NMH04_19290	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NMH04_19295	COG4853	Protein conserved in bacteria
NMH04_19300	COG4863	YycH protein
NMH04_19305	COG5002	protein histidine kinase activity
NMH04_19310	COG0745	RESPONSE REGULATOR receiver
NMH04_19335	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NMH04_19345	COG2311	Membrane
NMH04_19350	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NMH04_19355	COG1309	transcriptional regulator
NMH04_19360	COG2124	cytochrome p450
NMH04_19365	COG0346	lactoylglutathione lyase activity
NMH04_19370	COG0305	Participates in initiation and elongation during chromosome replication
NMH04_19385	COG2819	hydrolase of the alpha beta superfamily
NMH04_19390	COG1028	Short-chain dehydrogenase reductase Sdr
NMH04_19395	COG1169	isochorismate synthase
NMH04_19400	COG1021	2,3-dihydroxybenzoate-AMP ligase
NMH04_19405	COG1535	isochorismatase
NMH04_19405	COG3433	isochorismatase activity
NMH04_19410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NMH04_19415	COG3251	PFAM MbtH domain protein
NMH04_19420	COG2207	Transcriptional regulator
NMH04_19420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NMH04_19425	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NMH04_19430	COG2819	hydrolase of the alpha beta superfamily
NMH04_19435	COG3093	addiction module antidote protein HigA
NMH04_19440	COG2807	transmembrane transport
NMH04_19445	COG0359	binds to the 23S rRNA
NMH04_19450	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
NMH04_19455	COG4241	membrane
NMH04_19460	COG1227	inorganic diphosphatase activity
NMH04_19470	COG1595	DNA-templated transcription, initiation
NMH04_19480	COG0753	catalase activity
NMH04_19485	COG0655	NAD(P)H dehydrogenase (quinone) activity
NMH04_19490	COG0400	carboxylic ester hydrolase activity
NMH04_19495	COG0346	lactoylglutathione lyase activity
NMH04_19500	COG1174	glycine betaine transport
NMH04_19505	COG1125	glycine betaine transport
NMH04_19505	COG0517	IMP dehydrogenase activity
NMH04_19510	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NMH04_19515	COG0629	single-stranded DNA binding
NMH04_19520	COG0360	Binds together with S18 to 16S ribosomal RNA
NMH04_19525	COG0012	GTP binding
NMH04_19530	COG4481	Protein conserved in bacteria
NMH04_19545	COG3949	Membrane
NMH04_19555	COG1475	DNA binding
NMH04_19560	COG1192	Involved in chromosome partitioning
NMH04_19570	COG1475	DNA binding
NMH04_19575	COG0357	Ribosomal RNA small subunit methyltransferase G
NMH04_19580	COG0445	tRNA wobble uridine modification
NMH04_19585	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NMH04_19590	COG1847	R3H domain protein
NMH04_19595	COG0706	membrane insertase activity
NMH04_19600	COG0594	ribonuclease P activity
NMH04_19605	COG0230	Belongs to the bacterial ribosomal protein bL34 family