locus-tag	class	description
JNE42_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JNE42_00010	COG0592	DNA-directed DNA polymerase activity
JNE42_00015	COG2501	S4 domain
JNE42_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JNE42_00030	COG0187	DNA topoisomerase II activity
JNE42_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JNE42_00070	COG0517	IMP dehydrogenase activity
JNE42_00070	COG0516	GMP reductase activity
JNE42_00075	COG1686	Belongs to the peptidase S11 family
JNE42_00080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JNE42_00085	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JNE42_00090	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JNE42_00095	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JNE42_00100	COG0840	transmembrane signaling receptor activity
JNE42_00110	COG1428	Deoxynucleoside kinase
JNE42_00115	COG1428	Deoxynucleoside kinase
JNE42_00120	COG3858	chitin binding
JNE42_00120	COG1388	LysM domain
JNE42_00125	COG1335	isochorismatase
JNE42_00130	COG0590	tRNA wobble adenosine to inosine editing
JNE42_00140	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JNE42_00145	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JNE42_00150	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JNE42_00195	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
JNE42_00200	COG3853	Toxic anion resistance protein (TelA)
JNE42_00205	COG1982	Orn Lys Arg decarboxylase major
JNE42_00210	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JNE42_00215	COG3870	Protein conserved in bacteria
JNE42_00220	COG1728	Protein conserved in bacteria
JNE42_00225	COG0470	DNA polymerase III
JNE42_00230	COG1774	PSP1 C-terminal conserved region
JNE42_00235	COG4467	Involved in initiation control of chromosome replication
JNE42_00240	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JNE42_00245	COG2827	Endonuclease containing a URI domain
JNE42_00250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JNE42_00255	COG2002	toxin-antitoxin pair type II binding
JNE42_00260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JNE42_00260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JNE42_00265	COG0084	hydrolase, TatD family'
JNE42_00270	COG3584	3D domain protein
JNE42_00270	COG3583	domain protein
JNE42_00275	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JNE42_00280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JNE42_00295	COG4466	Protein conserved in bacteria
JNE42_00305	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JNE42_00310	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JNE42_00315	COG0251	oxidation-reduction process
JNE42_00320	COG2088	sporulation resulting in formation of a cellular spore
JNE42_00330	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JNE42_00335	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JNE42_00340	COG0193	aminoacyl-tRNA hydrolase activity
JNE42_00350	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JNE42_00355	COG2002	toxin-antitoxin pair type II binding
JNE42_00360	COG2244	polysaccharide biosynthetic process
JNE42_00365	COG3956	TIGRFAM MazG family protein
JNE42_00370	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JNE42_00385	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
JNE42_00390	COG1098	S1 RNA binding domain
JNE42_00405	COG2208	phosphoserine phosphatase activity
JNE42_00410	COG2304	oxidoreductase activity
JNE42_00415	COG0515	serine threonine protein kinase
JNE42_00420	COG0037	tRNA processing
JNE42_00425	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JNE42_00430	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JNE42_00435	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JNE42_00440	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JNE42_00445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JNE42_00450	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JNE42_00455	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JNE42_00460	COG0512	Glutamine amidotransferase of anthranilate synthase
JNE42_00465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JNE42_00470	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JNE42_00475	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JNE42_00480	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JNE42_00485	COG1396	sequence-specific DNA binding
JNE42_00490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JNE42_00495	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JNE42_00575	COG4463	regulation of RNA biosynthetic process
JNE42_00580	COG3880	PFAM UvrB UvrC protein
JNE42_00585	COG3869	Catalyzes the specific phosphorylation of arginine residues in
JNE42_00590	COG0542	response to heat
JNE42_00595	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JNE42_00600	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
JNE42_00605	COG4956	integral membrane protein (PIN domain superfamily)
JNE42_00610	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JNE42_00615	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JNE42_00620	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JNE42_00625	COG1045	serine acetyltransferase
JNE42_00630	COG0215	cysteine-tRNA ligase activity
JNE42_00635	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JNE42_00640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JNE42_00645	COG3688	RNA-binding protein containing a PIN domain
JNE42_00650	COG1595	DNA-templated transcription, initiation
JNE42_00655	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JNE42_00660	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JNE42_00665	COG0250	Participates in transcription elongation, termination and antitermination
JNE42_00675	COG0081	regulation of translation
JNE42_00680	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JNE42_00685	COG0222	ribosome binding
JNE42_00690	COG2813	Specifically methylates the guanine in position
JNE42_00695	COG0085	RNA polymerase activity
JNE42_00700	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JNE42_00705	COG1358	cellular component organization or biogenesis
JNE42_00710	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JNE42_00715	COG0049	tRNA binding
JNE42_00720	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JNE42_00725	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JNE42_00730	COG0596	Alpha beta hydrolase
JNE42_00740	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JNE42_00745	COG0088	Forms part of the polypeptide exit tunnel
JNE42_00750	COG0089	rRNA binding
JNE42_00755	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JNE42_00760	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JNE42_00765	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JNE42_00770	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JNE42_00775	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JNE42_00780	COG0255	Belongs to the universal ribosomal protein uL29 family
JNE42_00785	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JNE42_00790	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JNE42_00795	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JNE42_00800	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JNE42_00805	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JNE42_00810	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JNE42_00815	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JNE42_00820	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JNE42_00825	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JNE42_00830	COG1841	ribosomal large subunit assembly
JNE42_00835	COG0200	Binds to the 23S rRNA
JNE42_00840	COG0201	protein transport
JNE42_00845	COG0563	adenylate kinase activity
JNE42_00850	COG0024	Methionine aminopeptidase
JNE42_00855	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JNE42_00860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JNE42_00865	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JNE42_00870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JNE42_00875	COG0202	RNA polymerase activity
JNE42_00880	COG0203	ribosomal protein L17
JNE42_00885	COG1122	ATPase activity
JNE42_00890	COG1122	ATPase activity
JNE42_00895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JNE42_00900	COG0101	tRNA pseudouridine synthase activity
JNE42_00905	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JNE42_00910	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JNE42_00935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JNE42_00960	COG0860	N-Acetylmuramoyl-L-alanine amidase
JNE42_00965	COG0489	protein tyrosine kinase activity
JNE42_00975	COG2194	sulfuric ester hydrolase activity
JNE42_00980	COG0726	polysaccharide deacetylase
JNE42_01015	COG2856	Zn peptidase
JNE42_01025	COG1395	domain, Protein
JNE42_01085	COG0305	Participates in initiation and elongation during chromosome replication
JNE42_01205	COG1783	phage Terminase large subunit
JNE42_01210	COG5518	Phage portal protein
JNE42_01215	COG2369	cell adhesion
JNE42_01220	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JNE42_01225	COG4653	Phage capsid family
JNE42_01280	COG5280	Phage tail tape measure protein TP901
JNE42_01280	COG3953	SLT domain
JNE42_01280	COG3953	SLT domain
JNE42_01280	COG5280	Phage tail tape measure protein TP901
JNE42_01285	COG1652	LysM domain
JNE42_01290	COG4193	domain, Protein
JNE42_01300	COG3628	GPW Gp25 family protein
JNE42_01305	COG3299	homolog of phage Mu protein gp47
JNE42_01310	COG3778	Protein conserved in bacteria
JNE42_01345	COG3409	Peptidoglycan-binding domain 1 protein
JNE42_01345	COG5632	N-Acetylmuramoyl-L-alanine amidase
JNE42_01360	COG0457	Tetratricopeptide repeat
JNE42_01370	COG0659	secondary active sulfate transmembrane transporter activity
JNE42_01375	COG0385	Bile acid
JNE42_01380	COG3876	Protein conserved in bacteria
JNE42_01385	COG1472	Belongs to the glycosyl hydrolase 3 family
JNE42_01390	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JNE42_01395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JNE42_01395	COG1263	PTS System
JNE42_01400	COG1737	Transcriptional regulator
JNE42_01405	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JNE42_01440	COG1595	DNA-templated transcription, initiation
JNE42_01445	COG5662	AntiSigma factor
JNE42_01450	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JNE42_01455	COG4856	YbbR-like protein
JNE42_01460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JNE42_01465	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JNE42_01470	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JNE42_01475	COG0210	DNA helicase
JNE42_01495	COG1131	(ABC) transporter
JNE42_01505	COG1136	(ABC) transporter
JNE42_01515	COG1695	Transcriptional regulator
JNE42_01525	COG1131	(ABC) transporter
JNE42_01535	COG1413	lyase activity
JNE42_01540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JNE42_01555	COG2311	Membrane
JNE42_01575	COG1476	TRANSCRIPTIONal
JNE42_01585	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JNE42_01590	COG2207	Transcriptional regulator
JNE42_01595	COG1309	transcriptional regulator
JNE42_01610	COG1113	amino acid transport
JNE42_01615	COG0584	glycerophosphoryl diester phosphodiesterase
JNE42_01620	COG2271	Major facilitator Superfamily
JNE42_01630	COG1331	Highly conserved protein containing a thioredoxin domain
JNE42_01640	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JNE42_01660	COG0640	Transcriptional regulator
JNE42_01675	COG1937	Protein conserved in bacteria
JNE42_01680	COG2210	Belongs to the sulfur carrier protein TusA family
JNE42_01690	COG0425	Belongs to the sulfur carrier protein TusA family
JNE42_01690	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JNE42_01695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JNE42_01695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JNE42_01700	COG0425	Belongs to the sulfur carrier protein TusA family
JNE42_01705	COG0730	response to heat
JNE42_01715	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JNE42_01720	COG2814	Major facilitator Superfamily
JNE42_01735	COG1846	Transcriptional regulator
JNE42_01740	COG1683	Conserved Protein
JNE42_01750	COG0656	L-ascorbic acid biosynthetic process
JNE42_01755	COG0371	Dehydrogenase
JNE42_01760	COG1054	Belongs to the UPF0176 family
JNE42_01765	COG0531	amino acid
JNE42_01775	COG3711	transcriptional antiterminator
JNE42_01780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JNE42_01780	COG2190	(PTS) system
JNE42_01780	COG1263	PTS System
JNE42_01785	COG2723	6-phospho-beta-galactosidase activity
JNE42_01810	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JNE42_01810	COG3711	transcriptional antiterminator
JNE42_01815	COG1940	carbohydrate kinase activity
JNE42_01820	COG0383	alpha-mannosidase activity
JNE42_01825	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JNE42_01830	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JNE42_01835	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JNE42_01835	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JNE42_01840	COG1404	Belongs to the peptidase S8 family
JNE42_01855	COG0833	amino acid
JNE42_01860	COG2040	homocysteine
JNE42_01865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JNE42_01870	COG1695	Transcriptional regulator
JNE42_01885	COG2814	Major facilitator Superfamily
JNE42_01890	COG0456	acetyltransferase
JNE42_01905	COG1404	Belongs to the peptidase S8 family
JNE42_01915	COG1309	transcriptional regulator
JNE42_01920	COG1917	Cupin 2, conserved barrel domain protein
JNE42_01925	COG1063	alcohol dehydrogenase
JNE42_01930	COG1846	Transcriptional regulator
JNE42_01935	COG0318	PFAM AMP-dependent synthetase and ligase
JNE42_01940	COG0531	amino acid
JNE42_01950	COG0596	Alpha beta hydrolase
JNE42_01955	COG1115	amino acid carrier protein
JNE42_01960	COG2066	Belongs to the glutaminase family
JNE42_01965	COG4191	Histidine kinase
JNE42_01970	COG0784	Response regulator, receiver
JNE42_01975	COG1405	negative regulation of cell septum assembly
JNE42_01975	COG3012	SEC-C Motif Domain Protein
JNE42_01985	COG0667	Aldo Keto reductase
JNE42_01990	COG3290	protein histidine kinase activity
JNE42_01995	COG3279	Response regulator of the LytR AlgR family
JNE42_02000	COG4555	ABC transporter
JNE42_02005	COG1668	transmembrane transport
JNE42_02020	COG3773	Cell wall hydrolase
JNE42_02025	COG1028	Short-chain dehydrogenase reductase Sdr
JNE42_02035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JNE42_02040	COG2310	stress, protein
JNE42_02045	COG2310	stress, protein
JNE42_02050	COG2310	stress, protein
JNE42_02055	COG0861	Integral membrane protein TerC family
JNE42_02085	COG3853	Toxic anion resistance protein (TelA)
JNE42_02090	COG4175	Glycine betaine
JNE42_02090	COG0517	IMP dehydrogenase activity
JNE42_02095	COG4176	ABC-type proline glycine betaine transport system permease component
JNE42_02100	COG2113	Glycine betaine
JNE42_02115	COG1473	amidohydrolase
JNE42_02120	COG1288	antiporter activity
JNE42_02125	COG0039	L-malate dehydrogenase activity
JNE42_02130	COG1620	l-lactate permease
JNE42_02135	COG1609	Transcriptional regulator
JNE42_02140	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JNE42_02145	COG0561	phosphatase activity
JNE42_02150	COG0673	inositol 2-dehydrogenase activity
JNE42_02155	COG0738	Major facilitator superfamily
JNE42_02160	COG1280	lysine exporter protein (LysE YggA)
JNE42_02175	COG3403	YqcI/YcgG family
JNE42_02180	COG1113	amino acid transport
JNE42_02185	COG3665	Urea carboxylase-associated protein
JNE42_02190	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JNE42_02205	COG0457	Tetratricopeptide repeat
JNE42_02220	COG1012	belongs to the aldehyde dehydrogenase family
JNE42_02225	COG0710	3-dehydroquinate dehydratase activity
JNE42_02230	COG0028	Belongs to the TPP enzyme family
JNE42_02240	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JNE42_02245	COG2271	Major facilitator Superfamily
JNE42_02260	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JNE42_02265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JNE42_02275	COG0477	Major facilitator Superfamily
JNE42_02280	COG2226	methyltransferase
JNE42_02285	COG0583	DNA-binding transcription factor activity
JNE42_02290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JNE42_02295	COG3458	cephalosporin-C deacetylase activity
JNE42_02305	COG3541	Predicted nucleotidyltransferase
JNE42_02310	COG0506	proline dehydrogenase activity
JNE42_02315	COG1012	belongs to the aldehyde dehydrogenase family
JNE42_02320	COG2508	Transcriptional regulator
JNE42_02325	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JNE42_02330	COG0765	amino acid transport
JNE42_02335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JNE42_02345	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JNE42_02350	COG1522	sequence-specific DNA binding
JNE42_02355	COG2746	aminoglycoside 3-N-acetyltransferase activity
JNE42_02365	COG3290	protein histidine kinase activity
JNE42_02365	COG0840	transmembrane signaling receptor activity
JNE42_02370	COG3209	COG3209 Rhs family protein
JNE42_02390	COG3842	ATPase activity
JNE42_02395	COG1176	ABC-type spermidine putrescine transport system, permease component I
JNE42_02405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JNE42_02410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JNE42_02415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JNE42_02430	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
JNE42_02435	COG4555	ABC transporter
JNE42_02445	COG0697	spore germination
JNE42_02450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JNE42_02460	COG2207	Transcriptional regulator
JNE42_02460	COG3708	Transcriptional regulator
JNE42_02470	COG2364	Membrane
JNE42_02475	COG1126	abc transporter atp-binding protein
JNE42_02480	COG0765	amino acid transport
JNE42_02485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JNE42_02490	COG0412	Dienelactone hydrolase
JNE42_02495	COG0833	amino acid
JNE42_02500	COG3104	oligopeptide transport
JNE42_02505	COG5434	Belongs to the glycosyl hydrolase 28 family
JNE42_02510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JNE42_02515	COG0456	acetyltransferase
JNE42_02520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JNE42_02525	COG0765	amino acid transport
JNE42_02530	COG1126	abc transporter atp-binding protein
JNE42_02535	COG1473	amidohydrolase
JNE42_02540	COG2079	MmgE PrpD family protein
JNE42_02550	COG0745	RESPONSE REGULATOR receiver
JNE42_02555	COG5002	protein histidine kinase activity
JNE42_02555	COG3850	Histidine kinase
JNE42_02560	COG1366	Belongs to the anti-sigma-factor antagonist family
JNE42_02565	COG0527	aspartate kinase activity
JNE42_02570	COG2814	Major facilitator Superfamily
JNE42_02575	COG1309	transcriptional regulator
JNE42_02585	COG0640	Transcriptional regulator
JNE42_02590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JNE42_02595	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JNE42_02600	COG0531	amino acid
JNE42_02605	COG1012	belongs to the aldehyde dehydrogenase family
JNE42_02610	COG2249	NAD(P)H dehydrogenase (quinone) activity
JNE42_02615	COG4549	nuclear export factor GLE1
JNE42_02620	COG2372	response to copper ion
JNE42_02620	COG1276	copper resistance
JNE42_02625	COG2213	PTS system mannitol-specific
JNE42_02630	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JNE42_02635	COG0246	Mannitol dehydrogenase
JNE42_02640	COG0840	transmembrane signaling receptor activity
JNE42_02675	COG0346	lactoylglutathione lyase activity
JNE42_02690	COG0561	phosphatase activity
JNE42_02705	COG0457	Tetratricopeptide repeat
JNE42_02710	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JNE42_02715	COG1914	H( )-stimulated, divalent metal cation uptake system
JNE42_02720	COG4336	lyase activity
JNE42_02725	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JNE42_02730	COG1984	allophanate hydrolase subunit 2
JNE42_02735	COG1414	Transcriptional regulator
JNE42_02740	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JNE42_02745	COG2755	lipolytic protein G-D-S-L family
JNE42_02755	COG3711	transcriptional antiterminator
JNE42_02760	COG2226	methyltransferase
JNE42_02765	COG1028	Short-chain dehydrogenase reductase Sdr
JNE42_02770	COG3871	stress protein (general stress protein 26)
JNE42_02790	COG2814	Major facilitator Superfamily
JNE42_02795	COG0551	DNA topoisomerase type I activity
JNE42_02795	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JNE42_02800	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
JNE42_02805	COG3706	GGDEF domain
JNE42_02810	COG5298	Protein conserved in bacteria
JNE42_02815	COG1215	transferase activity, transferring glycosyl groups
JNE42_02825	COG0531	amino acid
JNE42_02830	COG0028	Belongs to the TPP enzyme family
JNE42_02880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JNE42_02885	COG1914	H( )-stimulated, divalent metal cation uptake system
JNE42_02890	COG2261	transglycosylase associated protein
JNE42_02895	COG2217	Heavy metal translocating P-type atpase
JNE42_02900	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JNE42_02905	COG3290	protein histidine kinase activity
JNE42_02910	COG4565	transcriptional regulatory protein
JNE42_02915	COG1301	dicarboxylic acid transport
JNE42_02920	COG0628	permease
JNE42_02925	COG1301	dicarboxylic acid transport
JNE42_02930	COG1131	(ABC) transporter
JNE42_02935	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JNE42_02950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JNE42_02955	COG1181	Belongs to the D-alanine--D-alanine ligase family
JNE42_02960	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JNE42_02975	COG0513	Belongs to the DEAD box helicase family
JNE42_02980	COG3402	PFAM membrane-flanked domain
JNE42_02985	COG3428	Bacterial PH domain
JNE42_02990	COG0705	Rhomboid family
JNE42_02995	COG0736	holo-[acyl-carrier-protein] synthase activity
JNE42_03000	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JNE42_03005	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JNE42_03010	COG0864	Transcriptional regulator
JNE42_03015	COG2337	Toxic component of a toxin-antitoxin (TA) module
JNE42_03020	COG1366	Belongs to the anti-sigma-factor antagonist family
JNE42_03025	COG1366	Belongs to the anti-sigma-factor antagonist family
JNE42_03030	COG2172	sigma factor antagonist activity
JNE42_03035	COG2208	phosphoserine phosphatase activity
JNE42_03040	COG1366	Belongs to the anti-sigma-factor antagonist family
JNE42_03045	COG2172	sigma factor antagonist activity
JNE42_03050	COG1191	sigma factor activity
JNE42_03055	COG2208	phosphoserine phosphatase activity
JNE42_03060	COG2183	response to ionizing radiation
JNE42_03070	COG3091	SprT-like family
JNE42_03075	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JNE42_03080	COG0022	dehydrogenase e1 component
JNE42_03085	COG0508	dehydrogenase complex catalyzes the overall conversion of
JNE42_03090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JNE42_03095	COG3284	Transcriptional regulator
JNE42_03140	COG1278	Cold shock
JNE42_03145	COG1329	Transcriptional regulator
JNE42_03150	COG1064	alcohol dehydrogenase
JNE42_03155	COG0789	Transcriptional regulator
JNE42_03170	COG0477	Major facilitator Superfamily
JNE42_03175	COG0657	acetylesterase activity
JNE42_03185	COG4221	oxidoreductase activity
JNE42_03195	COG0252	asparaginase activity
JNE42_03220	COG2814	Major facilitator Superfamily
JNE42_03225	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
JNE42_03230	COG2409	Drug exporters of the RND superfamily
JNE42_03235	COG4585	Histidine kinase
JNE42_03240	COG2197	response regulator
JNE42_03255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JNE42_03285	COG1309	transcriptional regulator
JNE42_03290	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JNE42_03295	COG1846	Transcriptional regulator
JNE42_03300	COG0778	Nitroreductase
JNE42_03315	COG1396	sequence-specific DNA binding
JNE42_03325	COG0456	acetyltransferase
JNE42_03335	COG4122	O-methyltransferase activity
JNE42_03345	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
JNE42_03350	COG0697	spore germination
JNE42_03360	COG1301	dicarboxylic acid transport
JNE42_03400	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JNE42_03405	COG0802	atpase or kinase
JNE42_03410	COG1214	PFAM Peptidase M22, glycoprotease
JNE42_03415	COG0456	acetyltransferase
JNE42_03420	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JNE42_03425	COG0488	(ABC) transporter
JNE42_03430	COG0315	cyclic pyranopterin monophosphate synthase activity
JNE42_03435	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JNE42_03440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JNE42_03445	COG0805	protein transport
JNE42_03460	COG1266	CAAX protease self-immunity
JNE42_03465	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JNE42_03470	COG0459	protein refolding
JNE42_03500	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JNE42_03505	COG0823	Involved in the tonB-independent uptake of proteins
JNE42_03515	COG2132	Multicopper oxidase
JNE42_03520	COG1113	amino acid transport
JNE42_03525	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JNE42_03530	COG0714	Associated with various cellular activities
JNE42_03535	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
JNE42_03540	COG1305	Transglutaminase-like
JNE42_03545	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JNE42_03545	COG0519	Catalyzes the synthesis of GMP from XMP
JNE42_03550	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JNE42_03560	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JNE42_03580	COG1404	Belongs to the peptidase S8 family
JNE42_03600	COG1595	DNA-templated transcription, initiation
JNE42_03610	COG2814	Major facilitator Superfamily
JNE42_03615	COG0583	DNA-binding transcription factor activity
JNE42_03620	COG2252	PERMEase
JNE42_03630	COG5583	Uncharacterized small protein (DUF2292)
JNE42_03635	COG3064	Membrane
JNE42_03640	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
JNE42_03650	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JNE42_03655	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JNE42_03660	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JNE42_03665	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JNE42_03670	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JNE42_03675	COG0047	phosphoribosylformylglycinamidine synthase activity
JNE42_03680	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JNE42_03685	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JNE42_03690	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JNE42_03695	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JNE42_03700	COG0138	bifunctional purine biosynthesis protein purh
JNE42_03705	COG0151	Belongs to the GarS family
JNE42_03725	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JNE42_03730	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JNE42_03735	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JNE42_03740	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JNE42_03750	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JNE42_03755	COG4496	protein, YerC YecD
JNE42_03765	COG0069	glutamate synthase activity
JNE42_03780	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
JNE42_03785	COG0210	DNA helicase
JNE42_03790	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JNE42_03795	COG4851	CamS sex pheromone cAM373 precursor
JNE42_03800	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JNE42_03805	COG1285	pathogenesis
JNE42_03810	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JNE42_03815	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JNE42_03820	COG0154	amidase activity
JNE42_03825	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JNE42_03830	COG1309	transcriptional regulator
JNE42_03835	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JNE42_03845	COG1957	nucleoside hydrolase
JNE42_03850	COG1597	lipid kinase activity
JNE42_03855	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JNE42_03890	COG5444	nuclease activity
JNE42_03895	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JNE42_03910	COG1959	2 iron, 2 sulfur cluster binding
JNE42_03915	COG0492	ferredoxin-NADP+ reductase activity
JNE42_03930	COG1486	melibiose metabolic process
JNE42_03940	COG2211	Major facilitator Superfamily
JNE42_03970	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JNE42_03975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JNE42_03980	COG1442	glycosyl transferase family 8
JNE42_03985	COG1216	Glycosyl transferase, family 2
JNE42_03990	COG1442	glycosyl transferase family 8
JNE42_03995	COG2223	nitrite transmembrane transporter activity
JNE42_04005	COG0471	metal ion transport
JNE42_04020	COG0071	Belongs to the small heat shock protein (HSP20) family
JNE42_04035	COG0531	amino acid
JNE42_04040	COG0463	Glycosyl transferase, family 2
JNE42_04040	COG0457	Tetratricopeptide repeat
JNE42_04045	COG0488	(ABC) transporter
JNE42_04050	COG1469	GTP cyclohydrolase I activity
JNE42_04055	COG0789	Transcriptional regulator
JNE42_04060	COG2814	Major facilitator Superfamily
JNE42_04065	COG0488	(ABC) transporter
JNE42_04070	COG0513	Belongs to the DEAD box helicase family
JNE42_04075	COG2130	NADP-dependent
JNE42_04095	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JNE42_04095	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JNE42_04100	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JNE42_04110	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JNE42_04110	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JNE42_04120	COG3290	protein histidine kinase activity
JNE42_04125	COG4565	transcriptional regulatory protein
JNE42_04130	COG3181	Tripartite tricarboxylate transporter family receptor
JNE42_04135	COG2851	Citrate transporter
JNE42_04145	COG3479	Phenolic acid decarboxylase
JNE42_04150	COG1695	Transcriptional regulator
JNE42_04155	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
JNE42_04165	COG1254	Belongs to the acylphosphatase family
JNE42_04170	COG2258	MOSC domain
JNE42_04185	COG0024	Methionine aminopeptidase
JNE42_04190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JNE42_04190	COG1263	PTS System
JNE42_04195	COG3739	integral membrane protein
JNE42_04210	COG1368	sulfuric ester hydrolase activity
JNE42_04215	COG0076	glutamate decarboxylase activity
JNE42_04230	COG1263	PTS System
JNE42_04230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JNE42_04235	COG0366	Alpha amylase catalytic
JNE42_04240	COG2188	Transcriptional regulator
JNE42_04250	COG0737	Belongs to the 5'-nucleotidase family
JNE42_04255	COG0693	protein deglycase activity
JNE42_04260	COG4840	Belongs to the UPF0435 family
JNE42_04265	COG1115	amino acid carrier protein
JNE42_04270	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JNE42_04275	COG4980	gas vesicle protein
JNE42_04280	COG1295	ribonuclease BN
JNE42_04285	COG0477	Major facilitator Superfamily
JNE42_04295	COG0387	Pfam Sodium calcium exchanger
JNE42_04305	COG0217	transcriptional regulatory protein
JNE42_04315	COG0668	transmembrane transport
JNE42_04320	COG0535	radical SAM domain protein
JNE42_04330	COG0726	polysaccharide deacetylase
JNE42_04340	COG0598	Magnesium transport protein CorA
JNE42_04350	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JNE42_04355	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JNE42_04380	COG0789	Transcriptional regulator
JNE42_04385	COG2814	Major facilitator Superfamily
JNE42_04435	COG2076	Multidrug Resistance protein
JNE42_04440	COG2076	Multidrug Resistance protein
JNE42_04445	COG1309	transcriptional regulator
JNE42_04455	COG4637	Psort location Cytoplasmic, score
JNE42_04460	COG2755	lipolytic protein G-D-S-L family
JNE42_04465	COG0492	ferredoxin-NADP+ reductase activity
JNE42_04470	COG2169	Transcriptional regulator
JNE42_04475	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JNE42_04480	COG1132	(ABC) transporter
JNE42_04485	COG1742	UPF0060 membrane protein
JNE42_04490	COG1595	DNA-templated transcription, initiation
JNE42_04510	COG2318	DinB family
JNE42_04520	COG1846	Transcriptional regulator
JNE42_04525	COG0392	lysyltransferase activity
JNE42_04525	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JNE42_04545	COG0778	Nitroreductase
JNE42_04560	COG1090	epimerase
JNE42_04565	COG2137	regulation of response to DNA damage stimulus
JNE42_04590	COG0463	Glycosyl transferase, family 2
JNE42_04595	COG4485	Bacterial membrane protein, YfhO
JNE42_04600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JNE42_04615	COG2140	Oxalate decarboxylase
JNE42_04625	COG1191	sigma factor activity
JNE42_04635	COG1988	membrane-bound metal-dependent
JNE42_04640	COG1194	a g-specific adenine glycosylase
JNE42_04650	COG1028	Short-chain dehydrogenase reductase Sdr
JNE42_04665	COG3557	Belongs to the UPF0374 family
JNE42_04670	COG1132	(ABC) transporter
JNE42_04675	COG0444	Belongs to the ABC transporter superfamily
JNE42_04680	COG4608	Belongs to the ABC transporter superfamily
JNE42_04685	COG0747	negative chemotaxis
JNE42_04690	COG0601	transmembrane transport
JNE42_04695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JNE42_04700	COG4129	membrane
JNE42_04705	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JNE42_04710	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JNE42_04715	COG0735	belongs to the Fur family
JNE42_04865	COG1368	sulfuric ester hydrolase activity
JNE42_04870	COG0681	Belongs to the peptidase S26 family
JNE42_04875	COG2873	o-acetylhomoserine
JNE42_04890	COG1131	(ABC) transporter
JNE42_04920	COG3382	B3 4 domain protein
JNE42_04925	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JNE42_04935	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JNE42_04940	COG2766	serine protein kinase
JNE42_04945	COG2718	Belongs to the UPF0229 family
JNE42_04950	COG1566	PFAM secretion protein HlyD family protein
JNE42_04955	COG2814	Major facilitator Superfamily
JNE42_04960	COG0655	NAD(P)H dehydrogenase (quinone) activity
JNE42_04970	COG1278	Cold shock
JNE42_04975	COG3706	GGDEF domain
JNE42_05000	COG5577	PFAM Coat F domain
JNE42_05005	COG5002	protein histidine kinase activity
JNE42_05010	COG0737	Belongs to the 5'-nucleotidase family
JNE42_05010	COG1525	nuclease
JNE42_05010	COG4085	toxin activity
JNE42_05015	COG3764	Sortase (surface protein transpeptidase)
JNE42_05020	COG0564	pseudouridine synthase activity
JNE42_05030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JNE42_05035	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JNE42_05035	COG3153	acetyltransferase
JNE42_05055	COG3835	regulator
JNE42_05060	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JNE42_05065	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JNE42_05070	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JNE42_05075	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JNE42_05080	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JNE42_05085	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JNE42_05090	COG4585	Histidine kinase
JNE42_05090	COG2203	Gaf domain
JNE42_05095	COG2197	response regulator
JNE42_05110	COG0753	catalase activity
JNE42_05115	COG1959	2 iron, 2 sulfur cluster binding
JNE42_05120	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JNE42_05120	COG1017	nitric oxide dioxygenase activity
JNE42_05125	COG2719	SpoVR family
JNE42_05130	COG1785	Belongs to the alkaline phosphatase family
JNE42_05135	COG0791	NLP P60 protein
JNE42_05135	COG1388	LysM domain
JNE42_05140	COG0531	amino acid
JNE42_05155	COG1595	DNA-templated transcription, initiation
JNE42_05160	COG0204	Acyl-transferase
JNE42_05165	COG1253	flavin adenine dinucleotide binding
JNE42_05170	COG0789	Transcriptional regulator
JNE42_05175	COG1253	flavin adenine dinucleotide binding
JNE42_05190	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JNE42_05195	COG0584	glycerophosphoryl diester phosphodiesterase
JNE42_05205	COG0668	transmembrane transport
JNE42_05210	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JNE42_05215	COG0726	polysaccharide deacetylase
JNE42_05220	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JNE42_05225	COG0589	response to stress
JNE42_05230	COG1132	(ABC) transporter
JNE42_05235	COG1132	(ABC) transporter
JNE42_05240	COG0702	epimerase
JNE42_05250	COG3842	ATPase activity
JNE42_05255	COG2508	Transcriptional regulator
JNE42_05265	COG0189	ligase activity
JNE42_05270	COG0189	ligase activity
JNE42_05275	COG4399	Belongs to the UPF0754 family
JNE42_05280	COG3679	Belongs to the UPF0342 family
JNE42_05285	COG0561	phosphatase activity
JNE42_05290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JNE42_05300	COG0475	glutathione-regulated potassium exporter activity
JNE42_05305	COG0490	domain, Protein
JNE42_05315	COG1024	Enoyl-CoA hydratase
JNE42_05325	COG0420	3'-5' exonuclease activity
JNE42_05330	COG4717	serine-type aminopeptidase activity
JNE42_05335	COG3481	metal-dependent phosphohydrolase, HD sub domain
JNE42_05345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JNE42_05370	COG1846	Transcriptional regulator
JNE42_05375	COG4980	gas vesicle protein
JNE42_05390	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JNE42_05395	COG0537	adenosine 5'-monophosphoramidase activity
JNE42_05400	COG1131	(ABC) transporter
JNE42_05405	COG4473	ABC transporter
JNE42_05415	COG1473	amidohydrolase
JNE42_05425	COG2329	Antibiotic biosynthesis monooxygenase
JNE42_05430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JNE42_05435	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JNE42_05440	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JNE42_05445	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JNE42_05450	COG1309	transcriptional regulator
JNE42_05455	COG1511	domain protein
JNE42_05460	COG1363	Peptidase, m42
JNE42_05465	COG1301	dicarboxylic acid transport
JNE42_05475	COG1234	tRNA 3'-trailer cleavage
JNE42_05480	COG0095	Lipoate-protein ligase
JNE42_05485	COG0318	PFAM AMP-dependent synthetase and ligase
JNE42_05495	COG0501	Belongs to the peptidase M48B family
JNE42_05500	COG1404	Belongs to the peptidase S8 family
JNE42_05505	COG0406	alpha-ribazole phosphatase activity
JNE42_05510	COG0840	transmembrane signaling receptor activity
JNE42_05515	COG0723	plastoquinol--plastocyanin reductase activity
JNE42_05515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JNE42_05520	COG1028	Short-chain dehydrogenase reductase Sdr
JNE42_05530	COG4903	ComK protein
JNE42_05545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JNE42_05550	COG2814	Major facilitator Superfamily
JNE42_05555	COG2732	(Barnase) inhibitor
JNE42_05560	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JNE42_05565	COG4605	iron ion homeostasis
JNE42_05570	COG4604	ABC transporter, ATP-binding protein
JNE42_05575	COG4607	ABC-type enterochelin transport system periplasmic component
JNE42_05580	COG1316	TRANSCRIPTIONal
JNE42_05595	COG0398	Pfam SNARE associated Golgi protein
JNE42_05600	COG0681	Belongs to the peptidase S26 family
JNE42_05605	COG3180	Ammonia monooxygenase
JNE42_05620	COG2259	Doxx family
JNE42_05625	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
JNE42_05630	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JNE42_05635	COG1074	ATP-dependent DNA helicase activity
JNE42_05640	COG0420	3'-5' exonuclease activity
JNE42_05645	COG0419	ATPase involved in DNA repair
JNE42_05650	COG1403	HNH endonuclease
JNE42_05690	COG5337	Spore coat protein CotH
JNE42_05695	COG0179	Fumarylacetoacetate (FAA) hydrolase
JNE42_05710	COG0367	asparagine synthase
JNE42_05725	COG1562	ergosterol biosynthetic process
JNE42_05730	COG0534	Mate efflux family protein
JNE42_05735	COG2207	Transcriptional regulator
JNE42_05735	COG1917	Cupin 2, conserved barrel domain protein
JNE42_05760	COG0076	glutamate decarboxylase activity
JNE42_05795	COG0646	methionine synthase
JNE42_05795	COG1410	methionine synthase
JNE42_05800	COG0646	methionine synthase
JNE42_05800	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JNE42_05805	COG1666	GTP binding
JNE42_05810	COG2996	Protein conserved in bacteria
JNE42_05815	COG1744	ABC transporter substrate-binding protein PnrA-like
JNE42_05820	COG0840	transmembrane signaling receptor activity
JNE42_05825	COG1307	EDD domain protein, DegV family
JNE42_05830	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JNE42_05850	COG0561	phosphatase activity
JNE42_05855	COG1073	alpha beta
JNE42_05860	COG2151	metal-sulfur cluster biosynthetic enzyme
JNE42_05865	COG0277	FAD linked oxidase domain protein
JNE42_05870	COG2271	Major facilitator Superfamily
JNE42_05875	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JNE42_05880	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JNE42_05885	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JNE42_05890	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JNE42_05895	COG0505	Belongs to the CarA family
JNE42_05900	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JNE42_05905	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JNE42_05915	COG2814	Major facilitator Superfamily
JNE42_05925	COG2267	carboxylic ester hydrolase activity
JNE42_05935	COG1744	ABC transporter substrate-binding protein PnrA-like
JNE42_05950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JNE42_05955	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JNE42_05960	COG5504	Zn-dependent protease
JNE42_05965	COG0444	Belongs to the ABC transporter superfamily
JNE42_05970	COG4608	Belongs to the ABC transporter superfamily
JNE42_05980	COG0601	transmembrane transport
JNE42_05985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JNE42_05995	COG0180	Tryptophanyl-tRNA synthetase
JNE42_06000	COG4166	transmembrane transport
JNE42_06005	COG0601	transmembrane transport
JNE42_06010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JNE42_06015	COG0444	Belongs to the ABC transporter superfamily
JNE42_06020	COG4608	Belongs to the ABC transporter superfamily
JNE42_06030	COG0456	acetyltransferase
JNE42_06035	COG1393	Belongs to the ArsC family
JNE42_06040	COG0861	Integral membrane protein TerC family
JNE42_06045	COG4862	establishment of competence for transformation
JNE42_06050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JNE42_06060	COG1164	Oligoendopeptidase f
JNE42_06070	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JNE42_06075	COG2346	COG2346, Truncated hemoglobins
JNE42_06080	COG0741	lytic transglycosylase activity
JNE42_06085	COG4116	CYTH
JNE42_06095	COG2357	RelA SpoT domain protein
JNE42_06100	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JNE42_06105	COG0564	pseudouridine synthase activity
JNE42_06110	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JNE42_06115	COG0475	glutathione-regulated potassium exporter activity
JNE42_06115	COG0569	domain protein
JNE42_06120	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JNE42_06125	COG0352	thiamine-phosphate diphosphorylase activity
JNE42_06135	COG2104	thiamine diphosphate biosynthetic process
JNE42_06140	COG2022	thiamine diphosphate biosynthetic process
JNE42_06145	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JNE42_06150	COG0351	phosphomethylpyrimidine kinase
JNE42_06155	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JNE42_06210	COG0210	DNA helicase
JNE42_06220	COG2153	protein acetylation
JNE42_06225	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JNE42_06230	COG2382	esterase
JNE42_06235	COG0626	cystathionine gamma-synthase activity
JNE42_06240	COG0626	cystathionine gamma-synthase activity
JNE42_06350	COG0825	malonyl-CoA metabolic process
JNE42_06370	COG2807	transmembrane transport
JNE42_06380	COG0583	DNA-binding transcription factor activity
JNE42_06395	COG0457	Tetratricopeptide repeat
JNE42_06415	COG3173	Aminoglycoside phosphotransferase
JNE42_06420	COG0583	DNA-binding transcription factor activity
JNE42_06440	COG0583	DNA-binding transcription factor activity
JNE42_06445	COG2807	transmembrane transport
JNE42_06475	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JNE42_06485	COG1309	transcriptional regulator
JNE42_06495	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JNE42_06500	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JNE42_06520	COG4195	phage-related replication protein
JNE42_06525	COG2856	Zn peptidase
JNE42_06530	COG3409	Peptidoglycan-binding domain 1 protein
JNE42_06530	COG5632	N-Acetylmuramoyl-L-alanine amidase
JNE42_06545	COG0306	phosphate transporter
JNE42_06550	COG1392	Phosphate transport regulator
JNE42_06560	COG0405	Gamma-glutamyltransferase
JNE42_06565	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JNE42_06575	COG4208	sulfate ABC transporter
JNE42_06580	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JNE42_06590	COG3775	system Galactitol-specific IIC component
JNE42_06605	COG1063	alcohol dehydrogenase
JNE42_06610	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JNE42_06615	COG0022	dehydrogenase e1 component
JNE42_06615	COG0508	dehydrogenase complex catalyzes the overall conversion of
JNE42_06620	COG0508	dehydrogenase complex catalyzes the overall conversion of
JNE42_06625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JNE42_06630	COG1028	Short-chain dehydrogenase reductase Sdr
JNE42_06635	COG1028	Short-chain dehydrogenase reductase Sdr
JNE42_06640	COG2390	Transcriptional regulator
JNE42_06650	COG0531	amino acid
JNE42_06655	COG0346	lactoylglutathione lyase activity
JNE42_06660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JNE42_06665	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JNE42_06670	COG2362	D-Aminopeptidase
JNE42_06675	COG0601	transmembrane transport
JNE42_06680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JNE42_06685	COG0444	Belongs to the ABC transporter superfamily
JNE42_06690	COG4166	transmembrane transport
JNE42_06695	COG1619	proteins homologs of microcin C7 resistance protein MccF
JNE42_06700	COG4948	Mandelate Racemase Muconate Lactonizing
JNE42_06705	COG0791	NLP P60 protein
JNE42_06710	COG4608	Belongs to the ABC transporter superfamily
JNE42_06715	COG1834	amidinotransferase
JNE42_06720	COG1607	acyl-coa hydrolase
JNE42_06725	COG1695	Transcriptional regulator
JNE42_06740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JNE42_06750	COG2076	Multidrug Resistance protein
JNE42_06755	COG2076	Multidrug Resistance protein
JNE42_06765	COG0788	formyltetrahydrofolate deformylase activity
JNE42_06770	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JNE42_06775	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JNE42_06780	COG0457	Tetratricopeptide repeat
JNE42_06790	COG1764	response to oxidative stress
JNE42_06795	COG1846	Transcriptional regulator
JNE42_06800	COG1764	response to oxidative stress
JNE42_06805	COG0590	tRNA wobble adenosine to inosine editing
JNE42_06810	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JNE42_06815	COG1404	Belongs to the peptidase S8 family
JNE42_06830	COG0745	RESPONSE REGULATOR receiver
JNE42_06835	COG3850	Histidine kinase
JNE42_06835	COG5002	protein histidine kinase activity
JNE42_06840	COG3212	peptidase
JNE42_06845	COG3212	peptidase
JNE42_06855	COG2239	Acts as a magnesium transporter
JNE42_06865	COG0583	DNA-binding transcription factor activity
JNE42_06875	COG0789	Transcriptional regulator
JNE42_06890	COG1846	Transcriptional regulator
JNE42_06895	COG3300	MHYT domain
JNE42_06895	COG5001	Diguanylate cyclase
JNE42_06900	COG0586	Pfam SNARE associated Golgi protein
JNE42_06905	COG0861	Integral membrane protein TerC family
JNE42_06910	COG1191	sigma factor activity
JNE42_06930	COG0501	Belongs to the peptidase M48B family
JNE42_06935	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JNE42_06940	COG2323	membrane
JNE42_06955	COG3594	Acyltransferase
JNE42_06960	COG5002	protein histidine kinase activity
JNE42_06965	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JNE42_06970	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JNE42_06975	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
JNE42_06980	COG0436	Aminotransferase
JNE42_06985	COG1850	ribulose-bisphosphate carboxylase activity
JNE42_06990	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
JNE42_06995	COG0235	Class ii aldolase
JNE42_07000	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
JNE42_07010	COG3852	Histidine kinase
JNE42_07015	COG1846	Transcriptional regulator
JNE42_07020	COG1360	Flagellar Motor Protein
JNE42_07025	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JNE42_07035	COG0542	response to heat
JNE42_07040	COG3949	Membrane
JNE42_07045	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JNE42_07050	COG0720	synthase
JNE42_07055	COG0602	queuosine metabolic process
JNE42_07060	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JNE42_07070	COG4873	Protein conserved in bacteria
JNE42_07080	COG3773	Cell wall hydrolase
JNE42_07085	COG2244	polysaccharide biosynthetic process
JNE42_07090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JNE42_07095	COG2217	Heavy metal translocating P-type atpase
JNE42_07100	COG0006	proline dipeptidase activity
JNE42_07105	COG1609	Transcriptional regulator
JNE42_07110	COG3711	transcriptional antiterminator
JNE42_07115	COG1263	PTS System
JNE42_07115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JNE42_07115	COG2190	(PTS) system
JNE42_07120	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JNE42_07125	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JNE42_07135	COG1533	DNA photolyase activity
JNE42_07140	COG0840	transmembrane signaling receptor activity
JNE42_07150	COG2084	Dehydrogenase
JNE42_07155	COG2340	Cysteine-rich secretory protein family
JNE42_07160	COG0768	penicillin binding
JNE42_07165	COG4191	Histidine kinase
JNE42_07170	COG0436	Aminotransferase
JNE42_07175	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JNE42_07185	COG1714	RDD family
JNE42_07195	COG0835	chemotaxis
JNE42_07195	COG0784	Response regulator, receiver
JNE42_07215	COG2814	Major facilitator Superfamily
JNE42_07220	COG1376	ErfK ybiS ycfS ynhG family protein
JNE42_07225	COG1408	metallophosphoesterase
JNE42_07230	COG1028	Short-chain dehydrogenase reductase Sdr
JNE42_07235	COG2200	EAL domain
JNE42_07240	COG3546	catalase activity
JNE42_07245	COG4703	Protein of unknown function (DUF1797)
JNE42_07250	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
JNE42_07260	COG0517	IMP dehydrogenase activity
JNE42_07265	COG0583	DNA-binding transcription factor activity
JNE42_07275	COG0716	FMN binding
JNE42_07285	COG0716	FMN binding
JNE42_07290	COG2171	N-acyltransferase activity
JNE42_07295	COG1473	amidohydrolase
JNE42_07305	COG0668	transmembrane transport
JNE42_07310	COG0450	alkyl hydroperoxide reductase
JNE42_07315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JNE42_07330	COG0746	molybdenum cofactor guanylyltransferase activity
JNE42_07335	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JNE42_07340	COG0303	'Molybdopterin
JNE42_07345	COG1763	Mo-molybdopterin cofactor biosynthetic process
JNE42_07350	COG0314	molybdopterin synthase activity
JNE42_07355	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JNE42_07370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JNE42_07375	COG1136	(ABC) transporter
JNE42_07380	COG0577	efflux transmembrane transporter activity
JNE42_07385	COG1349	DNA-binding transcription factor activity
JNE42_07390	COG1105	Belongs to the carbohydrate kinase PfkB family
JNE42_07395	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JNE42_07395	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JNE42_07395	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JNE42_07400	COG0681	Belongs to the peptidase S26 family
JNE42_07410	COG0488	(ABC) transporter
JNE42_07415	COG2309	aminopeptidase activity
JNE42_07425	COG1077	Cell shape determining protein MreB Mrl
JNE42_07430	COG2002	toxin-antitoxin pair type II binding
JNE42_07435	COG3852	Histidine kinase
JNE42_07440	COG2105	PFAM AIG2 family protein
JNE42_07440	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
JNE42_07445	COG0569	domain protein
JNE42_07450	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JNE42_07455	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JNE42_07460	COG5503	Protein of unknown function (DUF1447)
JNE42_07465	COG0561	phosphatase activity
JNE42_07470	COG0242	peptide deformylase activity
JNE42_07485	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JNE42_07490	COG0022	dehydrogenase e1 component
JNE42_07495	COG0508	dehydrogenase complex catalyzes the overall conversion of
JNE42_07500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JNE42_07505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JNE42_07515	COG1982	Orn Lys Arg decarboxylase major
JNE42_07520	COG4476	Belongs to the UPF0223 family
JNE42_07525	COG4493	Belongs to the UPF0637 family
JNE42_07535	COG0483	inositol monophosphate 1-phosphatase activity
JNE42_07550	COG1595	DNA-templated transcription, initiation
JNE42_07570	COG1217	gtp-binding protein TYPA
JNE42_07580	COG4896	Protein conserved in bacteria
JNE42_07590	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JNE42_07595	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JNE42_07600	COG2066	Belongs to the glutaminase family
JNE42_07605	COG4838	Belongs to the UPF0358 family
JNE42_07610	COG0772	Belongs to the SEDS family
JNE42_07615	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JNE42_07620	COG0415	Belongs to the DNA photolyase family
JNE42_07625	COG1612	heme a metabolic process
JNE42_07630	COG0109	protoheme IX farnesyltransferase activity
JNE42_07635	COG2010	Cytochrome c
JNE42_07635	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JNE42_07640	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JNE42_07645	COG1845	cytochrome c oxidase, subunit III
JNE42_07650	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JNE42_07655	COG3336	cytochrome c oxidase
JNE42_07665	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
JNE42_07670	COG2340	Cysteine-rich secretory protein family
JNE42_07690	COG3679	Belongs to the UPF0342 family
JNE42_07695	COG4471	UPF0298 protein
JNE42_07700	COG0742	ribosomal rna small subunit methyltransferase
JNE42_07705	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JNE42_07710	COG3314	Sporulation integral membrane protein YlbJ
JNE42_07715	COG1752	Esterase of the alpha-beta hydrolase superfamily
JNE42_07720	COG3480	Lon protease (S16) C-terminal proteolytic domain
JNE42_07730	COG1399	metal-binding, possibly nucleic acid-binding protein
JNE42_07735	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JNE42_07745	COG0454	-acetyltransferase
JNE42_07750	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JNE42_07755	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JNE42_07760	COG2001	Belongs to the MraZ family
JNE42_07765	COG0275	rRNA processing
JNE42_07770	COG4839	cell division protein FtsL
JNE42_07775	COG0768	penicillin binding
JNE42_07780	COG0768	penicillin binding
JNE42_07785	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JNE42_07790	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JNE42_07795	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JNE42_07800	COG0772	Belongs to the SEDS family
JNE42_07805	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JNE42_07810	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JNE42_07815	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JNE42_07820	COG3879	Bacterial protein of unknown function (DUF881)
JNE42_07825	COG3879	Bacterial protein of unknown function (DUF881)
JNE42_07830	COG3856	small basic protein
JNE42_07835	COG0849	cell division
JNE42_07840	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JNE42_07845	COG1404	Belongs to the peptidase S8 family
JNE42_07845	COG4412	M6 family metalloprotease domain protein
JNE42_07855	COG1191	sigma factor activity
JNE42_07860	COG1191	sigma factor activity
JNE42_07865	COG2390	Transcriptional regulator
JNE42_07880	COG3730	PTS system glucitol sorbitol-specific
JNE42_07885	COG3732	PTS system glucitol sorbitol-specific
JNE42_07895	COG1119	ATPase activity
JNE42_07900	COG1873	PFAM PRC-barrel domain
JNE42_07905	COG1496	oxidoreductase activity
JNE42_07910	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JNE42_07915	COG1799	cell septum assembly
JNE42_07920	COG0762	integral membrane protein
JNE42_07925	COG2302	S4 RNA-binding domain
JNE42_07930	COG3599	regulation of cell shape
JNE42_07935	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JNE42_07940	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JNE42_07945	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JNE42_07950	COG0564	pseudouridine synthase activity
JNE42_07955	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JNE42_07960	COG2233	PERMEase
JNE42_07965	COG0540	Belongs to the ATCase OTCase family
JNE42_07970	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JNE42_07975	COG0505	Belongs to the CarA family
JNE42_07980	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JNE42_07985	COG0543	2 iron, 2 sulfur cluster binding
JNE42_07990	COG0167	dihydroorotate dehydrogenase activity
JNE42_07995	COG0284	orotidine-5'-phosphate decarboxylase activity
JNE42_08000	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JNE42_08010	COG0175	sulfate reduction
JNE42_08015	COG0306	phosphate transporter
JNE42_08020	COG2046	Belongs to the sulfate adenylyltransferase family
JNE42_08025	COG0529	Catalyzes the synthesis of activated sulfate
JNE42_08030	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JNE42_08035	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
JNE42_08040	COG1648	precorrin-2 dehydrogenase activity
JNE42_08050	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JNE42_08055	COG1561	YicC-like family, N-terminal region
JNE42_08060	COG2052	Domain of unknown function (DUF370)
JNE42_08065	COG0194	GDP metabolic process
JNE42_08070	COG1758	RNA polymerase activity
JNE42_08075	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JNE42_08080	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JNE42_08085	COG0242	peptide deformylase activity
JNE42_08090	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JNE42_08095	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JNE42_08095	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JNE42_08100	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JNE42_08105	COG0631	protein serine/threonine phosphatase activity
JNE42_08110	COG2815	serine threonine protein kinase
JNE42_08110	COG0515	serine threonine protein kinase
JNE42_08115	COG1162	GTPase activity
JNE42_08120	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JNE42_08125	COG1564	THIamine pyrophosphokinase
JNE42_08135	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JNE42_08140	COG1302	Protein conserved in bacteria
JNE42_08145	COG1461	Dihydroxyacetone kinase
JNE42_08150	COG1760	l-serine dehydratase
JNE42_08155	COG1760	l-serine dehydratase
JNE42_08160	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JNE42_08165	COG1349	DNA-binding transcription factor activity
JNE42_08170	COG0416	fatty acid biosynthetic process
JNE42_08175	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JNE42_08180	COG1028	Short-chain dehydrogenase reductase Sdr
JNE42_08185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JNE42_08195	COG1196	nuclear chromosome segregation
JNE42_08200	COG0552	protein localization to endoplasmic reticulum
JNE42_08205	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JNE42_08210	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JNE42_08215	COG0228	four-way junction DNA binding
JNE42_08220	COG1837	Belongs to the UPF0109 family
JNE42_08230	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JNE42_08235	COG0336	Belongs to the RNA methyltransferase TrmD family
JNE42_08240	COG0335	large ribosomal subunit rRNA binding
JNE42_08245	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JNE42_08250	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JNE42_08260	COG2257	FlhB HrpN YscU SpaS Family
JNE42_08265	COG0045	succinate-CoA ligase (ADP-forming) activity
JNE42_08270	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JNE42_08275	COG0758	DNA mediated transformation
JNE42_08280	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JNE42_08285	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JNE42_08290	COG4974	Belongs to the 'phage' integrase family
JNE42_08295	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JNE42_08300	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JNE42_08305	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JNE42_08310	COG1815	bacterial-type flagellum-dependent cell motility
JNE42_08315	COG1558	bacterial-type flagellum-dependent cell motility
JNE42_08320	COG1677	Flagellar hook-basal body complex protein FliE
JNE42_08325	COG1766	The M ring may be actively involved in energy transduction
JNE42_08330	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JNE42_08335	COG1317	bacterial-type flagellum organization
JNE42_08340	COG1157	protein secretion by the type III secretion system
JNE42_08345	COG2882	bacterial-type flagellum organization
JNE42_08350	COG3334	PFAM MgtE intracellular
JNE42_08355	COG3144	bacterial-type flagellum assembly
JNE42_08360	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
JNE42_08365	COG4786	Flagellar basal body rod
JNE42_08370	COG1582	Flagellar protein (FlbD)
JNE42_08375	COG1580	Controls the rotational direction of flagella during chemotaxis
JNE42_08380	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JNE42_08385	COG1776	CheC inhibitor of MCP methylation
JNE42_08385	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JNE42_08390	COG2201	protein-glutamate methylesterase activity
JNE42_08395	COG3190	flagellar
JNE42_08400	COG1338	Plays a role in the flagellum-specific transport system
JNE42_08405	COG1987	bacterial-type flagellum assembly
JNE42_08410	COG1684	flagellar biosynthetic protein fliR
JNE42_08415	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JNE42_08420	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JNE42_08425	COG1419	protein localization to endoplasmic reticulum
JNE42_08430	COG0455	bacterial-type flagellum organization
JNE42_08435	COG2201	protein-glutamate methylesterase activity
JNE42_08440	COG0643	Histidine kinase
JNE42_08440	COG2198	Histidine kinase
JNE42_08445	COG0835	chemotaxis
JNE42_08450	COG1776	CheC inhibitor of MCP methylation
JNE42_08460	COG1191	sigma factor activity
JNE42_08475	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JNE42_08480	COG0528	UMP kinase activity
JNE42_08485	COG0233	cytoplasmic translational termination
JNE42_08490	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JNE42_08495	COG4589	Belongs to the CDS family
JNE42_08500	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JNE42_08505	COG0750	zinc metalloprotease
JNE42_08510	COG0442	prolyl-tRNA aminoacylation
JNE42_08515	COG2176	DNA-directed DNA polymerase activity
JNE42_08530	COG3693	PFAM glycoside hydrolase, family 10
JNE42_08540	COG0779	Required for maturation of 30S ribosomal subunits
JNE42_08545	COG0195	Participates in both transcription termination and antitermination
JNE42_08550	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JNE42_08555	COG1358	cellular component organization or biogenesis
JNE42_08560	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JNE42_08565	COG1550	Protein conserved in bacteria
JNE42_08570	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JNE42_08575	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JNE42_08580	COG0196	riboflavin kinase activity
JNE42_08585	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JNE42_08590	COG1185	polyribonucleotide nucleotidyltransferase activity
JNE42_08595	COG0726	polysaccharide deacetylase
JNE42_08600	COG0612	Peptidase, M16
JNE42_08610	COG1873	PFAM PRC-barrel domain
JNE42_08615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JNE42_08620	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JNE42_08625	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JNE42_08630	COG0527	aspartate kinase activity
JNE42_08640	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JNE42_08645	COG0740	serine-type endopeptidase activity
JNE42_08655	COG4980	gas vesicle protein
JNE42_08655	COG1674	ftsk spoiiie
JNE42_08660	COG2188	Transcriptional regulator
JNE42_08665	COG2814	Major facilitator Superfamily
JNE42_08670	COG2409	Drug exporters of the RND superfamily
JNE42_08670	COG1033	growth of symbiont in host cell
JNE42_08675	COG0612	Peptidase, M16
JNE42_08680	COG0612	Peptidase, M16
JNE42_08690	COG2409	Drug exporters of the RND superfamily
JNE42_08690	COG1033	growth of symbiont in host cell
JNE42_08695	COG0300	oxidoreductase activity
JNE42_08710	COG1426	Protein conserved in bacteria
JNE42_08715	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JNE42_08720	COG1546	Belongs to the CinA family
JNE42_08720	COG1058	Belongs to the CinA family
JNE42_08725	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JNE42_08730	COG1418	mRNA catabolic process
JNE42_08735	COG1692	metallophosphoesterase
JNE42_08740	COG2359	stage V sporulation protein S
JNE42_08745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JNE42_08750	COG1063	alcohol dehydrogenase
JNE42_08755	COG0156	8-amino-7-oxononanoate synthase activity
JNE42_08765	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JNE42_08770	COG4550	Control of competence regulator ComK, YlbF/YmcA
JNE42_08780	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JNE42_08785	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JNE42_08810	COG1329	Transcriptional regulator
JNE42_08815	COG4195	phage-related replication protein
JNE42_08820	COG0457	Tetratricopeptide repeat
JNE42_08825	COG1404	Belongs to the peptidase S8 family
JNE42_08830	COG4195	phage-related replication protein
JNE42_08835	COG1764	response to oxidative stress
JNE42_08840	COG2076	Multidrug Resistance protein
JNE42_08865	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JNE42_08870	COG1923	regulation of RNA biosynthetic process
JNE42_08885	COG1780	Probably involved in ribonucleotide reductase function
JNE42_08890	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JNE42_08895	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JNE42_08900	COG4112	unkown
JNE42_08910	COG0464	growth
JNE42_08915	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JNE42_08920	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JNE42_08925	COG0789	Transcriptional regulator
JNE42_08930	COG0174	glutamine synthetase
JNE42_08950	COG0494	nUDIX hydrolase
JNE42_08955	COG0457	Tetratricopeptide repeat
JNE42_08975	COG5444	nuclease activity
JNE42_09000	COG5646	InterPro IPR014922
JNE42_09020	COG0457	Tetratricopeptide repeat
JNE42_09030	COG3619	membrane
JNE42_09035	COG3285	dna ligase
JNE42_09035	COG1793	dna ligase
JNE42_09040	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
JNE42_09045	COG4876	unkown
JNE42_09055	COG1959	2 iron, 2 sulfur cluster binding
JNE42_09060	COG0702	epimerase
JNE42_09070	COG0247	lactate metabolic process
JNE42_09075	COG1139	Iron-sulfur cluster binding protein
JNE42_09080	COG1556	Lactate utilization protein
JNE42_09100	COG2323	membrane
JNE42_09105	COG1309	transcriptional regulator
JNE42_09110	COG2124	cytochrome p450
JNE42_09110	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JNE42_09115	COG3591	Belongs to the peptidase S1B family
JNE42_09120	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JNE42_09125	COG3209	COG3209 Rhs family protein
JNE42_09130	COG1366	Belongs to the anti-sigma-factor antagonist family
JNE42_09145	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JNE42_09150	COG1388	LysM domain
JNE42_09155	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JNE42_09160	COG4224	UPF0291 protein
JNE42_09165	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JNE42_09175	COG3763	UPF0154 protein
JNE42_09185	COG0785	Cytochrome C biogenesis protein
JNE42_09190	COG4846	Membrane protein involved in cytochrome C biogenesis
JNE42_09200	COG0071	Belongs to the small heat shock protein (HSP20) family
JNE42_09215	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JNE42_09220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JNE42_09240	COG0824	Thioesterase
JNE42_09250	COG4841	protein insertion into membrane
JNE42_09255	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JNE42_09260	COG1832	CoA-binding protein
JNE42_09265	COG0187	DNA topoisomerase II activity
JNE42_09270	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JNE42_09280	COG0738	Major facilitator superfamily
JNE42_09285	COG0473	3-isopropylmalate dehydrogenase activity
JNE42_09290	COG0110	maltose O-acetyltransferase activity
JNE42_09305	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JNE42_09310	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JNE42_09320	COG1309	transcriptional regulator
JNE42_09325	COG2249	NAD(P)H dehydrogenase (quinone) activity
JNE42_09330	COG1733	regulation of RNA biosynthetic process
JNE42_09335	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JNE42_09340	COG0251	oxidation-reduction process
JNE42_09385	COG2205	protein histidine kinase activity
JNE42_09390	COG0745	RESPONSE REGULATOR receiver
JNE42_09400	COG3507	Belongs to the glycosyl hydrolase 43 family
JNE42_09405	COG1012	belongs to the aldehyde dehydrogenase family
JNE42_09410	COG1486	melibiose metabolic process
JNE42_09415	COG0395	ABC-type sugar transport system, permease component
JNE42_09420	COG1175	transmembrane transport
JNE42_09425	COG1653	transport
JNE42_09430	COG1609	Transcriptional regulator
JNE42_09435	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JNE42_09450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JNE42_09465	COG5444	nuclease activity
JNE42_09470	COG1846	Transcriptional regulator
JNE42_09475	COG2814	Major facilitator Superfamily
JNE42_09485	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JNE42_09485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JNE42_09485	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JNE42_09490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JNE42_09490	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JNE42_09490	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JNE42_09495	COG1105	Belongs to the carbohydrate kinase PfkB family
JNE42_09505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JNE42_09525	COG1012	belongs to the aldehyde dehydrogenase family
JNE42_09530	COG3591	Belongs to the peptidase S1B family
JNE42_09540	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JNE42_09545	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JNE42_09550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JNE42_09555	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JNE42_09560	COG1024	Enoyl-CoA hydratase
JNE42_09565	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JNE42_09570	COG0511	ligase activity, forming carbon-carbon bonds
JNE42_09575	COG0439	Biotin carboxylase
JNE42_09580	COG0318	PFAM AMP-dependent synthetase and ligase
JNE42_09585	COG1960	acyl-CoA dehydrogenase activity
JNE42_09590	COG1649	PFAM Uncharacterised BCR, COG1649
JNE42_09595	COG2365	Tyrosine phosphatase family
JNE42_09600	COG1349	DNA-binding transcription factor activity
JNE42_09605	COG1942	4-Oxalocrotonate Tautomerase
JNE42_09615	COG3835	regulator
JNE42_09620	COG0277	FAD linked oxidase domain protein
JNE42_09625	COG0247	lactate metabolic process
JNE42_09645	COG0166	Belongs to the GPI family
JNE42_09650	COG2246	polysaccharide biosynthetic process
JNE42_09655	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JNE42_09660	COG0586	Pfam SNARE associated Golgi protein
JNE42_09665	COG1587	Uroporphyrinogen-III synthase
JNE42_09675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JNE42_09690	COG0534	Mate efflux family protein
JNE42_09695	COG2027	D-alanyl-D-alanine carboxypeptidase
JNE42_09700	COG4677	pectinesterase activity
JNE42_09705	COG2323	membrane
JNE42_09710	COG2146	nitrite reductase [NAD(P)H] activity
JNE42_09715	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JNE42_09720	COG0243	molybdopterin cofactor binding
JNE42_09725	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JNE42_09730	COG2223	nitrite transmembrane transporter activity
JNE42_09735	COG0493	'glutamate synthase
JNE42_09740	COG0069	glutamate synthase activity
JNE42_09740	COG0067	glutamate synthase
JNE42_09740	COG0070	glutamate synthase
JNE42_09745	COG0583	DNA-binding transcription factor activity
JNE42_09755	COG1132	(ABC) transporter
JNE42_09760	COG0789	Transcriptional regulator
JNE42_09760	COG4978	Transcriptional regulator
JNE42_09765	COG0454	-acetyltransferase
JNE42_09775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JNE42_09780	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JNE42_09785	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JNE42_09790	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JNE42_09800	COG0243	molybdopterin cofactor binding
JNE42_09810	COG1070	Carbohydrate kinase
JNE42_09815	COG2115	Belongs to the xylose isomerase family
JNE42_09820	COG1940	carbohydrate kinase activity
JNE42_09830	COG2211	Major facilitator Superfamily
JNE42_09835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JNE42_09840	COG1994	Peptidase M50
JNE42_09860	COG1309	transcriptional regulator
JNE42_09865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JNE42_09870	COG3708	Transcriptional regulator
JNE42_09875	COG2378	regulation of single-species biofilm formation
JNE42_09885	COG0640	Transcriptional regulator
JNE42_09890	COG0531	amino acid
JNE42_09895	COG0741	lytic transglycosylase activity
JNE42_09900	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JNE42_09905	COG2079	MmgE PrpD family protein
JNE42_09910	COG0372	Belongs to the citrate synthase family
JNE42_09915	COG2322	membrane
JNE42_09925	COG1388	LysM domain
JNE42_09925	COG3584	3D domain protein
JNE42_09930	COG0514	ATP-dependent DNA helicase (RecQ)
JNE42_09940	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JNE42_09965	COG1012	belongs to the aldehyde dehydrogenase family
JNE42_09970	COG1657	PFAM Prenyltransferase squalene oxidase
JNE42_09975	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JNE42_09980	COG0385	Bile acid
JNE42_09985	COG0508	dehydrogenase complex catalyzes the overall conversion of
JNE42_09990	COG0567	Dehydrogenase, E1 component
JNE42_09995	COG4548	von Willebrand factor, type A
JNE42_10000	COG0714	Associated with various cellular activities
JNE42_10005	COG2032	superoxide dismutase activity
JNE42_10010	COG1388	LysM domain
JNE42_10010	COG0791	NLP P60 protein
JNE42_10015	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JNE42_10020	COG0534	Mate efflux family protein
JNE42_10025	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JNE42_10030	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JNE42_10040	COG2962	Rard protein
JNE42_10055	COG1733	regulation of RNA biosynthetic process
JNE42_10060	COG0778	Nitroreductase
JNE42_10070	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JNE42_10075	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JNE42_10080	COG0793	Belongs to the peptidase S41A family
JNE42_10080	COG3409	Peptidoglycan-binding domain 1 protein
JNE42_10085	COG2226	methyltransferase
JNE42_10095	COG1876	peptidase activity
JNE42_10100	COG0813	purine-nucleoside phosphorylase activity
JNE42_10110	COG0671	phosphoesterase, PA-phosphatase related
JNE42_10130	COG4479	Belongs to the UPF0346 family
JNE42_10140	COG1509	lysine 2,3-aminomutase activity
JNE42_10145	COG3829	transcription factor binding
JNE42_10150	COG0463	Glycosyl transferase, family 2
JNE42_10165	COG4641	Protein conserved in bacteria
JNE42_10175	COG1086	Polysaccharide biosynthesis protein
JNE42_10180	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JNE42_10185	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JNE42_10190	COG1846	Transcriptional regulator
JNE42_10210	COG4698	Protein conserved in bacteria
JNE42_10215	COG2755	lipolytic protein G-D-S-L family
JNE42_10220	COG1999	signal sequence binding
JNE42_10235	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JNE42_10240	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JNE42_10245	COG1272	protein, Hemolysin III
JNE42_10250	COG0204	Acyl-transferase
JNE42_10255	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JNE42_10260	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JNE42_10265	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JNE42_10275	COG2521	methyltransferase
JNE42_10275	COG2136	Putative SAM-dependent methyltransferase
JNE42_10285	COG0129	dihydroxy-acid dehydratase activity
JNE42_10290	COG1413	lyase activity
JNE42_10295	COG1418	mRNA catabolic process
JNE42_10300	COG0386	Belongs to the glutathione peroxidase family
JNE42_10305	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JNE42_10310	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JNE42_10315	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JNE42_10325	COG1278	Cold shock
JNE42_10340	COG0328	RNA-DNA hybrid ribonuclease activity
JNE42_10345	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JNE42_10350	COG0328	RNA-DNA hybrid ribonuclease activity
JNE42_10360	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JNE42_10370	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JNE42_10380	COG1755	Isoprenylcysteine carboxyl methyltransferase
JNE42_10385	COG3424	synthase
JNE42_10390	COG0726	polysaccharide deacetylase
JNE42_10395	COG2233	PERMEase
JNE42_10400	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JNE42_10405	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JNE42_10410	COG1199	ATP-dependent helicase activity
JNE42_10420	COG0116	Belongs to the methyltransferase superfamily
JNE42_10430	COG3599	regulation of cell shape
JNE42_10435	COG4474	Belongs to the UPF0398 family
JNE42_10445	COG3359	exonuclease
JNE42_10450	COG1111	helicase
JNE42_10450	COG1205	dead DEAH box helicase
JNE42_10455	COG1902	pentaerythritol trinitrate reductase activity
JNE42_10460	COG2190	(PTS) system
JNE42_10465	COG0071	Belongs to the small heat shock protein (HSP20) family
JNE42_10500	COG3331	DNA recombination
JNE42_10505	COG4499	WXG100 protein secretion system (Wss), protein YukC
JNE42_10505	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JNE42_10515	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JNE42_10520	COG3935	DnaD domain protein
JNE42_10525	COG0017	Asparaginyl-tRNA synthetase
JNE42_10530	COG5353	protein conserved in bacteria
JNE42_10540	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JNE42_10540	COG1199	ATP-dependent helicase activity
JNE42_10545	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JNE42_10550	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JNE42_10555	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JNE42_10565	COG0617	tRNA 3'-terminal CCA addition
JNE42_10570	COG0438	transferase activity, transferring glycosyl groups
JNE42_10575	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JNE42_10580	COG1803	Methylglyoxal synthase
JNE42_10585	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JNE42_10590	COG1694	Mazg nucleotide pyrophosphohydrolase
JNE42_10595	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JNE42_10605	COG4347	Protein of unknown function (DUF1405)
JNE42_10610	COG2010	Cytochrome c
JNE42_10610	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JNE42_10615	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JNE42_10620	COG0723	plastoquinol--plastocyanin reductase activity
JNE42_10630	COG5582	Belongs to the UPF0302 family
JNE42_10635	COG0457	Tetratricopeptide repeat
JNE42_10640	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JNE42_10645	COG0287	Prephenate dehydrogenase
JNE42_10650	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JNE42_10655	COG0159	tryptophan synthase activity
JNE42_10660	COG0133	tryptophan synthase activity
JNE42_10670	COG0134	indole-3-glycerol-phosphate synthase activity
JNE42_10675	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JNE42_10685	COG4401	Chorismate mutase type I
JNE42_10690	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JNE42_10695	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JNE42_10700	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JNE42_10705	COG0105	UTP biosynthetic process
JNE42_10710	COG0142	geranyltranstransferase activity
JNE42_10715	COG2226	methyltransferase
JNE42_10720	COG0142	geranyltranstransferase activity
JNE42_10730	COG0302	gtp cyclohydrolase
JNE42_10735	COG0776	regulation of translation
JNE42_10740	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JNE42_10755	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JNE42_10760	COG1160	GTP binding
JNE42_10785	COG1304	FMN binding
JNE42_10790	COG0539	negative regulation of cytoplasmic translation
JNE42_10795	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JNE42_10805	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
JNE42_10810	COG2959	enzyme of heme biosynthesis
JNE42_10815	COG3773	Cell wall hydrolase
JNE42_10815	COG3409	Peptidoglycan-binding domain 1 protein
JNE42_10820	COG2339	peptidase activity
JNE42_10825	COG0492	ferredoxin-NADP+ reductase activity
JNE42_10830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JNE42_10835	COG4862	establishment of competence for transformation
JNE42_10840	COG1408	metallophosphoesterase
JNE42_10850	COG1388	LysM domain
JNE42_10855	COG1266	CAAX protease self-immunity
JNE42_10860	COG0514	ATP-dependent DNA helicase (RecQ)
JNE42_10865	COG4955	Helix-turn-helix domain
JNE42_10870	COG1141	Ferredoxin
JNE42_10875	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JNE42_10880	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JNE42_10895	COG1595	DNA-templated transcription, initiation
JNE42_10900	COG5002	protein histidine kinase activity
JNE42_10905	COG0745	RESPONSE REGULATOR receiver
JNE42_10910	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JNE42_10915	COG1333	cytochrome c biogenesis protein
JNE42_10920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JNE42_10925	COG1187	pseudouridine synthase activity
JNE42_10930	COG0700	Nucleoside recognition
JNE42_10935	COG2715	membrane protein required for spore maturation
JNE42_10940	COG1686	Belongs to the peptidase S11 family
JNE42_10955	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JNE42_10960	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JNE42_10970	COG1547	Domain of unknown function (DUF309)
JNE42_10975	COG0456	acetyltransferase
JNE42_10980	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JNE42_10985	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JNE42_10985	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JNE42_10990	COG0307	riboflavin synthase, alpha
JNE42_11010	COG2814	Major facilitator Superfamily
JNE42_11015	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JNE42_11020	COG4086	secreted protein
JNE42_11025	COG0019	diaminopimelate decarboxylase activity
JNE42_11030	COG0697	spore germination
JNE42_11045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JNE42_11065	COG1191	sigma factor activity
JNE42_11070	COG2172	sigma factor antagonist activity
JNE42_11080	COG1686	Belongs to the peptidase S11 family
JNE42_11085	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JNE42_11090	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JNE42_11095	COG4974	Belongs to the 'phage' integrase family
JNE42_11105	COG0735	belongs to the Fur family
JNE42_11110	COG1300	Membrane
JNE42_11115	COG1404	Belongs to the peptidase S8 family
JNE42_11125	COG2153	protein acetylation
JNE42_11130	COG1379	DNA repair
JNE42_11135	COG0494	nUDIX hydrolase
JNE42_11140	COG0667	Aldo Keto reductase
JNE42_11155	COG1073	alpha beta
JNE42_11160	COG0457	Tetratricopeptide repeat
JNE42_11170	COG4918	Iron-sulphur cluster biosynthesis
JNE42_11175	COG4305	rare lipoprotein A
JNE42_11180	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JNE42_11180	COG0456	acetyltransferase
JNE42_11185	COG0456	acetyltransferase
JNE42_11195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JNE42_11205	COG2211	Major facilitator Superfamily
JNE42_11210	COG1072	(Pantothenic acid kinase))
JNE42_11215	COG0446	pyridine nucleotide-disulphide oxidoreductase
JNE42_11225	COG0300	oxidoreductase activity
JNE42_11230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JNE42_11235	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JNE42_11245	COG4187	Peptidase family M20/M25/M40
JNE42_11250	COG1902	pentaerythritol trinitrate reductase activity
JNE42_11255	COG0596	Alpha beta hydrolase
JNE42_11260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JNE42_11270	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JNE42_11275	COG2188	Transcriptional regulator
JNE42_11280	COG2723	6-phospho-beta-galactosidase activity
JNE42_11285	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JNE42_11290	COG1447	Phosphotransferase system cellobiose-specific component IIA
JNE42_11295	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JNE42_11305	COG1028	Short-chain dehydrogenase reductase Sdr
JNE42_11315	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JNE42_11320	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JNE42_11330	COG0706	membrane insertase activity
JNE42_11335	COG0835	chemotaxis
JNE42_11340	COG2195	Cleaves the N-terminal amino acid of tripeptides
JNE42_11345	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JNE42_11350	COG0346	lactoylglutathione lyase activity
JNE42_11360	COG1376	ErfK ybiS ycfS ynhG family protein
JNE42_11365	COG4129	membrane
JNE42_11370	COG1126	abc transporter atp-binding protein
JNE42_11375	COG0765	amino acid transport
JNE42_11380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JNE42_11390	COG1597	lipid kinase activity
JNE42_11400	COG0508	dehydrogenase complex catalyzes the overall conversion of
JNE42_11405	COG0022	dehydrogenase e1 component
JNE42_11410	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JNE42_11415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JNE42_11420	COG3426	butyrate kinase activity
JNE42_11425	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JNE42_11430	COG0280	phosphate acetyltransferase
JNE42_11435	COG3290	protein histidine kinase activity
JNE42_11435	COG3829	transcription factor binding
JNE42_11445	COG0584	glycerophosphoryl diester phosphodiesterase
JNE42_11450	COG0457	Tetratricopeptide repeat
JNE42_11455	COG0745	RESPONSE REGULATOR receiver
JNE42_11460	COG0750	zinc metalloprotease
JNE42_11465	COG0497	DNA recombination
JNE42_11470	COG1438	arginine binding
JNE42_11475	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JNE42_11480	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JNE42_11485	COG0142	geranyltranstransferase activity
JNE42_11490	COG1722	exodeoxyribonuclease VII activity
JNE42_11495	COG1570	exodeoxyribonuclease VII activity
JNE42_11500	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JNE42_11505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JNE42_11510	COG1302	Protein conserved in bacteria
JNE42_11515	COG0439	Biotin carboxylase
JNE42_11520	COG0511	ligase activity, forming carbon-carbon bonds
JNE42_11560	COG3854	ATPases associated with a variety of cellular activities
JNE42_11570	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JNE42_11575	COG0006	proline dipeptidase activity
JNE42_11580	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JNE42_11590	COG3872	metal-dependent enzyme
JNE42_11600	COG1752	Esterase of the alpha-beta hydrolase superfamily
JNE42_11605	COG1321	iron dependent repressor
JNE42_11610	COG0095	Lipoate-protein ligase
JNE42_11615	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JNE42_11620	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JNE42_11625	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JNE42_11630	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JNE42_11635	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JNE42_11660	COG0681	Belongs to the peptidase S26 family
JNE42_11695	COG4970	Tfp pilus assembly protein FimT
JNE42_11700	COG4537	Required for transformation and DNA binding
JNE42_11705	COG1459	type II secretion system
JNE42_11710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JNE42_11715	COG1366	Belongs to the anti-sigma-factor antagonist family
JNE42_11725	COG1393	Belongs to the ArsC family
JNE42_11735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JNE42_11745	COG0011	TIGRFAM Protein of
JNE42_11750	COG2814	Major facilitator Superfamily
JNE42_11755	COG2866	Carboxypeptidase
JNE42_11760	COG1368	sulfuric ester hydrolase activity
JNE42_11765	COG1940	carbohydrate kinase activity
JNE42_11770	COG4483	Protein conserved in bacteria
JNE42_11775	COG0705	Rhomboid family
JNE42_11775	COG0457	Tetratricopeptide repeat
JNE42_11790	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JNE42_11795	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JNE42_11805	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JNE42_11810	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JNE42_11815	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JNE42_11820	COG0581	inorganic phosphate transmembrane transporter activity
JNE42_11825	COG0573	inorganic phosphate transmembrane transporter activity
JNE42_11830	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JNE42_11835	COG0768	penicillin binding
JNE42_11840	COG0477	Major facilitator Superfamily
JNE42_11845	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JNE42_11850	COG2839	Protein conserved in bacteria
JNE42_11855	COG5521	maltodextrose utilization protein MalA
JNE42_11860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JNE42_11865	COG1388	LysM domain
JNE42_11870	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JNE42_11875	COG4709	membrane
JNE42_11880	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
JNE42_11885	COG1940	carbohydrate kinase activity
JNE42_11890	COG0735	belongs to the Fur family
JNE42_11895	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JNE42_11900	COG1121	(ABC) transporter
JNE42_11905	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JNE42_11920	COG0513	Belongs to the DEAD box helicase family
JNE42_11930	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JNE42_11940	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JNE42_11945	COG2384	SAM-dependent methyltransferase
JNE42_11950	COG2010	Cytochrome c
JNE42_11955	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JNE42_11960	COG0358	DNA primase activity
JNE42_11965	COG1671	Belongs to the UPF0178 family
JNE42_11970	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JNE42_11975	COG0517	IMP dehydrogenase activity
JNE42_11980	COG0751	glycine-tRNA ligase activity
JNE42_11985	COG0752	glycyl-tRNA synthetase alpha subunit
JNE42_11990	COG1381	Involved in DNA repair and RecF pathway recombination
JNE42_12000	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JNE42_12005	COG0295	cytidine deaminase activity
JNE42_12010	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JNE42_12015	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JNE42_12020	COG1480	7TM receptor with intracellular HD hydrolase
JNE42_12025	COG1702	phosphate starvation-inducible protein PhoH
JNE42_12030	COG0561	phosphatase activity
JNE42_12045	COG4864	UPF0365 protein
JNE42_12050	COG1030	water channel activity
JNE42_12055	COG1610	YqeY-like protein
JNE42_12065	COG1283	sodium-dependent phosphate transmembrane transporter activity
JNE42_12070	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JNE42_12075	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JNE42_12080	COG2264	protein methyltransferase activity
JNE42_12085	COG0484	heat shock protein binding
JNE42_12090	COG0443	Heat shock 70 kDa protein
JNE42_12095	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JNE42_12100	COG1420	regulation of RNA biosynthetic process
JNE42_12105	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JNE42_12110	COG0481	GTPase activity
JNE42_12120	COG0860	N-Acetylmuramoyl-L-alanine amidase
JNE42_12125	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
JNE42_12130	COG0268	Binds directly to 16S ribosomal RNA
JNE42_12135	COG1466	dna polymerase III delta subunit
JNE42_12145	COG2333	competence protein COMEC
JNE42_12145	COG0658	competence protein
JNE42_12150	COG2131	deaminase
JNE42_12155	COG1555	photosystem II stabilization
JNE42_12155	COG1596	polysaccharide export
JNE42_12160	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JNE42_12165	COG2226	methyltransferase
JNE42_12170	COG0799	negative regulation of ribosome biogenesis
JNE42_12175	COG1713	HD superfamily hydrolase involved in NAD metabolism
JNE42_12180	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JNE42_12185	COG1534	Rna-binding protein
JNE42_12190	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JNE42_12195	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JNE42_12200	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JNE42_12215	COG2755	lipolytic protein G-D-S-L family
JNE42_12225	COG0457	Tetratricopeptide repeat
JNE42_12250	COG0726	polysaccharide deacetylase
JNE42_12285	COG1131	(ABC) transporter
JNE42_12310	COG2160	L-arabinose isomerase activity
JNE42_12325	COG1609	Transcriptional regulator
JNE42_12345	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JNE42_12350	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
JNE42_12355	COG1733	regulation of RNA biosynthetic process
JNE42_12360	COG0657	acetylesterase activity
JNE42_12395	COG2602	Beta-lactamase
JNE42_12400	COG1960	acyl-CoA dehydrogenase activity
JNE42_12405	COG1126	abc transporter atp-binding protein
JNE42_12410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JNE42_12415	COG0765	amino acid transport
JNE42_12425	COG1063	alcohol dehydrogenase
JNE42_12435	COG1028	Short-chain dehydrogenase reductase Sdr
JNE42_12445	COG1115	amino acid carrier protein
JNE42_12450	COG0583	DNA-binding transcription factor activity
JNE42_12455	COG1063	alcohol dehydrogenase
JNE42_12460	COG2226	methyltransferase
JNE42_12485	COG0626	cystathionine gamma-synthase activity
JNE42_12490	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JNE42_12495	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JNE42_12500	COG2226	methyltransferase
JNE42_12515	COG0768	penicillin binding
JNE42_12520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JNE42_12525	COG0572	uridine kinase
JNE42_12530	COG0826	peptidase U32
JNE42_12535	COG0826	peptidase U32
JNE42_12540	COG4122	O-methyltransferase activity
JNE42_12545	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JNE42_12550	COG0183	Belongs to the thiolase family
JNE42_12555	COG0318	PFAM AMP-dependent synthetase and ligase
JNE42_12560	COG1268	BioY protein
JNE42_12565	COG3906	Belongs to the UPF0473 family
JNE42_12570	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JNE42_12575	COG4472	Bacterial protein of unknown function (DUF965)
JNE42_12580	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JNE42_12585	COG0628	permease
JNE42_12590	COG1126	abc transporter atp-binding protein
JNE42_12595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JNE42_12600	COG0765	amino acid transport
JNE42_12605	COG0765	amino acid transport
JNE42_12620	COG3881	PFAM PRC-barrel domain
JNE42_12625	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JNE42_12630	COG0457	Tetratricopeptide repeat
JNE42_12635	COG0482	sulfurtransferase activity
JNE42_12640	COG1104	cysteine desulfurase activity
JNE42_12645	COG1959	2 iron, 2 sulfur cluster binding
JNE42_12650	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JNE42_12655	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JNE42_12670	COG0124	histidyl-tRNA synthetase
JNE42_12680	COG0860	N-Acetylmuramoyl-L-alanine amidase
JNE42_12680	COG3103	Sh3 type 3 domain protein
JNE42_12680	COG4991	sh3 domain protein
JNE42_12685	COG1490	D-aminoacyl-tRNA deacylase activity
JNE42_12690	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JNE42_12695	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JNE42_12700	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JNE42_12700	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JNE42_12705	COG5416	Lipopolysaccharide assembly protein A domain
JNE42_12710	COG0490	domain, Protein
JNE42_12720	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JNE42_12720	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JNE42_12730	COG2244	polysaccharide biosynthetic process
JNE42_12735	COG2323	membrane
JNE42_12745	COG1862	Preprotein translocase
JNE42_12750	COG0343	queuine tRNA-ribosyltransferase activity
JNE42_12755	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JNE42_12765	COG2255	four-way junction helicase activity
JNE42_12770	COG0632	four-way junction helicase activity
JNE42_12780	COG2112	serine threonine protein kinase
JNE42_12795	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JNE42_12810	COG1388	LysM domain
JNE42_12815	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JNE42_12820	COG0157	Belongs to the NadC ModD family
JNE42_12825	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JNE42_12830	COG1104	cysteine desulfurase activity
JNE42_12835	COG1827	regulation of RNA biosynthetic process
JNE42_12840	COG0077	Prephenate dehydratase
JNE42_12845	COG4492	Belongs to the UPF0735 family
JNE42_12850	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JNE42_12855	COG3290	protein histidine kinase activity
JNE42_12860	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JNE42_12865	COG2868	ribosomal protein
JNE42_12870	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JNE42_12875	COG1994	Peptidase M50
JNE42_12880	COG0739	heme binding
JNE42_12885	COG2894	cell division
JNE42_12890	COG0850	regulation of cytokinetic process
JNE42_12895	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JNE42_12905	COG1077	Cell shape determining protein MreB Mrl
JNE42_12910	COG2003	Belongs to the UPF0758 family
JNE42_12915	COG0424	maF-like protein
JNE42_12930	COG0285	dihydrofolate synthase activity
JNE42_12935	COG0525	valine-tRNA ligase activity
JNE42_12945	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JNE42_12950	COG1388	LysM domain
JNE42_12955	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JNE42_12960	COG0113	porphobilinogen synthase activity
JNE42_12965	COG1587	Uroporphyrinogen-III synthase
JNE42_12970	COG0181	hydroxymethylbilane synthase activity
JNE42_12975	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JNE42_12980	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JNE42_13005	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JNE42_13010	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JNE42_13015	COG0470	DNA polymerase III
JNE42_13015	COG1067	ATP-dependent peptidase activity
JNE42_13020	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JNE42_13025	COG0544	peptidyl-prolyl cis-trans isomerase activity
JNE42_13030	COG0457	Tetratricopeptide repeat
JNE42_13030	COG1477	protein flavinylation
JNE42_13035	COG0066	3-isopropylmalate dehydratase activity
JNE42_13040	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JNE42_13045	COG0473	3-isopropylmalate dehydrogenase activity
JNE42_13050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JNE42_13055	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JNE42_13060	COG0440	acetolactate synthase activity
JNE42_13065	COG0028	Belongs to the TPP enzyme family
JNE42_13070	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JNE42_13075	COG2706	6-phosphogluconolactonase activity
JNE42_13080	COG3339	Conserved Protein
JNE42_13085	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JNE42_13090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JNE42_13095	COG1696	Membrane protein involved in D-alanine export
JNE42_13100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JNE42_13140	COG0622	Phosphoesterase
JNE42_13145	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JNE42_13150	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JNE42_13155	COG5401	PFAM Sporulation and spore germination
JNE42_13160	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JNE42_13165	COG1846	Transcriptional regulator
JNE42_13170	COG2197	response regulator
JNE42_13175	COG2851	Citrate transporter
JNE42_13180	COG0583	DNA-binding transcription factor activity
JNE42_13185	COG2828	Protein conserved in bacteria
JNE42_13195	COG0824	Thioesterase
JNE42_13200	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JNE42_13205	COG1053	succinate dehydrogenase
JNE42_13210	COG2009	succinate dehydrogenase
JNE42_13215	COG1719	4-vinyl reductase, 4VR
JNE42_13220	COG0527	aspartate kinase activity
JNE42_13225	COG0322	excinuclease ABC activity
JNE42_13230	COG3118	belongs to the thioredoxin family
JNE42_13235	COG3534	alpha-L-arabinofuranosidase
JNE42_13240	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JNE42_13245	COG2086	electron transfer activity
JNE42_13250	COG1024	Enoyl-CoA hydratase
JNE42_13255	COG1309	transcriptional regulator
JNE42_13260	COG0318	PFAM AMP-dependent synthetase and ligase
JNE42_13270	COG3766	membrane
JNE42_13275	COG1193	negative regulation of DNA recombination
JNE42_13280	COG1796	DNA polymerase
JNE42_13280	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JNE42_13285	COG1286	toxin biosynthetic process
JNE42_13290	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JNE42_13295	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JNE42_13300	COG0072	phenylalanine-tRNA ligase activity
JNE42_13300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JNE42_13305	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JNE42_13310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JNE42_13325	COG1363	Peptidase, m42
JNE42_13335	COG3326	Membrane
JNE42_13340	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JNE42_13345	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JNE42_13350	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JNE42_13365	COG1011	Hydrolase
JNE42_13375	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JNE42_13385	COG0398	Pfam SNARE associated Golgi protein
JNE42_13390	COG1484	DNA-dependent DNA replication
JNE42_13395	COG3611	Membrane attachment protein
JNE42_13400	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JNE42_13410	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JNE42_13415	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JNE42_13420	COG0237	dephospho-CoA kinase activity
JNE42_13425	COG1971	Probably functions as a manganese efflux pump
JNE42_13430	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JNE42_13435	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JNE42_13435	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JNE42_13440	COG5002	protein histidine kinase activity
JNE42_13445	COG0745	RESPONSE REGULATOR receiver
JNE42_13450	COG0039	L-malate dehydrogenase activity
JNE42_13455	COG0538	isocitrate dehydrogenase activity
JNE42_13460	COG0372	Belongs to the citrate synthase family
JNE42_13465	COG2707	UPF0756 membrane protein
JNE42_13470	COG0628	permease
JNE42_13475	COG3030	protein affecting phage T7 exclusion by the F plasmid
JNE42_13485	COG0205	6-phosphofructokinase activity
JNE42_13490	COG0825	malonyl-CoA metabolic process
JNE42_13495	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JNE42_13500	COG0281	malic enzyme
JNE42_13505	COG0587	DNA-directed DNA polymerase activity
JNE42_13525	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JNE42_13535	COG4109	DRTGG domain
JNE42_13540	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JNE42_13545	COG1028	Short-chain dehydrogenase reductase Sdr
JNE42_13555	COG0165	Argininosuccinate lyase
JNE42_13560	COG0137	argininosuccinate synthase activity
JNE42_13565	COG0521	Mo-molybdopterin cofactor biosynthetic process
JNE42_13570	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JNE42_13575	COG0827	DNA restriction-modification system
JNE42_13580	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JNE42_13585	COG3874	Sporulation protein YtfJ
JNE42_13595	COG1714	RDD family
JNE42_13600	COG0616	signal peptide processing
JNE42_13605	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JNE42_13615	COG3239	Fatty acid desaturase
JNE42_13620	COG4585	Histidine kinase
JNE42_13625	COG2197	response regulator
JNE42_13630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JNE42_13635	COG0745	RESPONSE REGULATOR receiver
JNE42_13640	COG2205	protein histidine kinase activity
JNE42_13645	COG1136	(ABC) transporter
JNE42_13650	COG0577	efflux transmembrane transporter activity
JNE42_13655	COG0402	S-adenosylhomocysteine deaminase activity
JNE42_13660	COG2249	NAD(P)H dehydrogenase (quinone) activity
JNE42_13680	COG1279	arginine transmembrane transporter activity
JNE42_13685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JNE42_13695	COG0301	tRNA thio-modification
JNE42_13700	COG1104	cysteine desulfurase activity
JNE42_13705	COG1114	Component of the transport system for branched-chain amino acids
JNE42_13710	COG1114	Component of the transport system for branched-chain amino acids
JNE42_13715	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JNE42_13720	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JNE42_13725	COG1309	transcriptional regulator
JNE42_13730	COG1956	GAF domain-containing protein
JNE42_13735	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JNE42_13745	COG1335	isochorismatase
JNE42_13755	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JNE42_13760	COG2329	Antibiotic biosynthesis monooxygenase
JNE42_13765	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JNE42_13770	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JNE42_13775	COG0454	-acetyltransferase
JNE42_13780	COG0517	IMP dehydrogenase activity
JNE42_13785	COG0123	including yeast histone deacetylase and acetoin utilization protein
JNE42_13790	COG1609	Transcriptional regulator
JNE42_13795	COG1605	Chorismate mutase
JNE42_13795	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JNE42_13800	COG3118	belongs to the thioredoxin family
JNE42_13805	COG4980	gas vesicle protein
JNE42_13810	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JNE42_13815	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JNE42_13820	COG1674	ftsk spoiiie
JNE42_13825	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JNE42_13830	COG4848	Belongs to the UPF0354 family
JNE42_13835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JNE42_13850	COG1363	Peptidase, m42
JNE42_13855	COG5584	Small secreted protein
JNE42_13860	COG0281	malic enzyme
JNE42_13865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JNE42_13870	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JNE42_13880	COG0510	thiamine kinase activity
JNE42_13885	COG1597	lipid kinase activity
JNE42_13895	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JNE42_13900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JNE42_13905	COG3340	Belongs to the peptidase S51 family
JNE42_13910	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JNE42_13915	COG2252	PERMEase
JNE42_13920	COG1349	DNA-binding transcription factor activity
JNE42_13925	COG1187	pseudouridine synthase activity
JNE42_13930	COG2244	polysaccharide biosynthetic process
JNE42_13935	COG2081	HI0933 family
JNE42_13945	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JNE42_13950	COG3196	Protein conserved in bacteria
JNE42_13960	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JNE42_13965	COG5578	integral membrane protein
JNE42_13970	COG0673	inositol 2-dehydrogenase activity
JNE42_13975	COG1653	transport
JNE42_13980	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
JNE42_13985	COG4209	transmembrane transport
JNE42_13990	COG2207	Transcriptional regulator
JNE42_13995	COG1733	regulation of RNA biosynthetic process
JNE42_14000	COG2814	Major facilitator Superfamily
JNE42_14005	COG0656	L-ascorbic acid biosynthetic process
JNE42_14010	COG1653	transport
JNE42_14015	COG0395	ABC-type sugar transport system, permease component
JNE42_14020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JNE42_14025	COG1073	alpha beta
JNE42_14030	COG0495	leucyl-tRNA aminoacylation
JNE42_14040	COG2202	Pas domain
JNE42_14040	COG1366	Belongs to the anti-sigma-factor antagonist family
JNE42_14045	COG2433	Pfam Transposase IS66
JNE42_14050	COG0577	efflux transmembrane transporter activity
JNE42_14055	COG1136	(ABC) transporter
JNE42_14065	COG1131	(ABC) transporter
JNE42_14070	COG1725	Transcriptional regulator
JNE42_14090	COG1242	4 iron, 4 sulfur cluster binding
JNE42_14095	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JNE42_14110	COG2267	carboxylic ester hydrolase activity
JNE42_14115	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JNE42_14120	COG0367	asparagine synthase
JNE42_14125	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JNE42_14130	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JNE42_14140	COG1506	peptidase
JNE42_14145	COG1233	COG1233 Phytoene dehydrogenase and related
JNE42_14165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JNE42_14170	COG1116	anion transmembrane transporter activity
JNE42_14175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JNE42_14180	COG0494	nUDIX hydrolase
JNE42_14185	COG2310	stress, protein
JNE42_14200	COG4824	toxin secretion phage lysis holin
JNE42_14210	COG0783	Belongs to the Dps family
JNE42_14225	COG1854	S-ribosylhomocysteine lyase activity
JNE42_14230	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JNE42_14235	COG0288	reversible hydration of carbon dioxide
JNE42_14240	COG0803	Belongs to the bacterial solute-binding protein 9 family
JNE42_14240	COG3443	Belongs to the bacterial solute-binding protein 9 family
JNE42_14250	COG1271	oxidase subunit
JNE42_14255	COG1294	oxidase, subunit
JNE42_14270	COG4948	Mandelate Racemase Muconate Lactonizing
JNE42_14275	COG0318	PFAM AMP-dependent synthetase and ligase
JNE42_14280	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JNE42_14285	COG0596	Alpha beta hydrolase
JNE42_14290	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JNE42_14295	COG1169	isochorismate synthase
JNE42_14300	COG1575	Belongs to the MenA family. Type 1 subfamily
JNE42_14305	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JNE42_14435	COG3859	Proton-coupled thiamine transporter YuaJ
JNE42_14440	COG1247	-acetyltransferase
JNE42_14445	COG3339	Conserved Protein
JNE42_14450	COG0772	Belongs to the SEDS family
JNE42_14455	COG0772	Belongs to the SEDS family
JNE42_14460	COG2268	Band 7 protein
JNE42_14465	COG1585	Membrane protein implicated in regulation of membrane protease activity
JNE42_14470	COG2318	DinB family
JNE42_14475	COG1454	alcohol dehydrogenase
JNE42_14480	COG1012	belongs to the aldehyde dehydrogenase family
JNE42_14485	COG1510	regulation of RNA biosynthetic process
JNE42_14500	COG4978	Transcriptional regulator
JNE42_14500	COG0789	Transcriptional regulator
JNE42_14505	COG0456	acetyltransferase
JNE42_14510	COG5632	N-Acetylmuramoyl-L-alanine amidase
JNE42_14510	COG3409	Peptidoglycan-binding domain 1 protein
JNE42_14565	COG3778	Protein conserved in bacteria
JNE42_14570	COG3299	homolog of phage Mu protein gp47
JNE42_14575	COG3628	GPW Gp25 family protein
JNE42_14585	COG4193	domain, Protein
JNE42_14590	COG1652	LysM domain
JNE42_14595	COG3953	SLT domain
JNE42_14595	COG5280	Phage tail tape measure protein TP901
JNE42_14595	COG3953	SLT domain
JNE42_14595	COG5280	Phage tail tape measure protein TP901
JNE42_14650	COG4653	Phage capsid family
JNE42_14655	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JNE42_14660	COG5518	Phage portal protein
JNE42_14665	COG1783	phage Terminase large subunit
JNE42_14670	COG5484	DNA packaging
JNE42_14675	COG1595	DNA-templated transcription, initiation
JNE42_14685	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
JNE42_14705	COG1396	sequence-specific DNA binding
JNE42_14715	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JNE42_14730	COG0628	permease
JNE42_14740	COG0673	inositol 2-dehydrogenase activity
JNE42_14745	COG0693	protein deglycase activity
JNE42_14750	COG0840	transmembrane signaling receptor activity
JNE42_14755	COG0840	transmembrane signaling receptor activity
JNE42_14760	COG0840	transmembrane signaling receptor activity
JNE42_14765	COG0840	transmembrane signaling receptor activity
JNE42_14780	COG2070	2-Nitropropane dioxygenase
JNE42_14785	COG0432	Pfam Uncharacterised protein family UPF0047
JNE42_14790	COG1253	flavin adenine dinucleotide binding
JNE42_14795	COG2738	Putative neutral zinc metallopeptidase
JNE42_14805	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JNE42_14820	COG0166	Belongs to the GPI family
JNE42_14825	COG1979	alcohol dehydrogenase
JNE42_14830	COG1979	alcohol dehydrogenase
JNE42_14835	COG2155	Conserved Protein
JNE42_14840	COG1098	S1 RNA binding domain
JNE42_14845	COG0436	Aminotransferase
JNE42_14850	COG1522	sequence-specific DNA binding
JNE42_14855	COG2267	carboxylic ester hydrolase activity
JNE42_14865	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JNE42_14870	COG2205	protein histidine kinase activity
JNE42_14885	COG5018	Exonuclease
JNE42_14890	COG2814	Major facilitator Superfamily
JNE42_14895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JNE42_14900	COG3011	Protein conserved in bacteria
JNE42_14910	COG3290	protein histidine kinase activity
JNE42_14915	COG4565	transcriptional regulatory protein
JNE42_14920	COG1744	ABC transporter substrate-binding protein PnrA-like
JNE42_14925	COG3845	ABC transporter
JNE42_14930	COG4603	Belongs to the binding-protein-dependent transport system permease family
JNE42_14935	COG1079	Belongs to the binding-protein-dependent transport system permease family
JNE42_14940	COG3493	citrate carrier protein
JNE42_14950	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JNE42_14950	COG2111	Na H antiporter
JNE42_14955	COG2111	Na H antiporter
JNE42_14960	COG1006	Multisubunit Na H antiporter MnhC subunit
JNE42_14965	COG0651	ATP synthesis coupled electron transport
JNE42_14970	COG1863	multisubunit Na H antiporter MnhE subunit
JNE42_14975	COG2212	antiporter activity
JNE42_14980	COG1320	monovalent cation:proton antiporter activity
JNE42_14985	COG2050	protein possibly involved in aromatic compounds catabolism
JNE42_14990	COG2197	response regulator
JNE42_14995	COG4585	Histidine kinase
JNE42_15005	COG0142	geranyltranstransferase activity
JNE42_15020	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JNE42_15025	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JNE42_15030	COG1335	isochorismatase
JNE42_15035	COG5506	Protein of unknown function (DUF1694)
JNE42_15055	COG0628	permease
JNE42_15070	COG1418	mRNA catabolic process
JNE42_15075	COG1028	Short-chain dehydrogenase reductase Sdr
JNE42_15085	COG1511	domain protein
JNE42_15090	COG1674	ftsk spoiiie
JNE42_15090	COG0433	COG0433 Predicted ATPase
JNE42_15095	COG4499	WXG100 protein secretion system (Wss), protein YukC
JNE42_15100	COG5417	Belongs to the EsaB family
JNE42_15105	COG4842	Belongs to the WXG100 family
JNE42_15110	COG2508	Transcriptional regulator
JNE42_15110	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JNE42_15115	COG0686	Belongs to the AlaDH PNT family
JNE42_15120	COG1268	BioY protein
JNE42_15125	COG2056	Na+-H+ antiporter family
JNE42_15130	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JNE42_15135	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
JNE42_15140	COG3584	3D domain protein
JNE42_15155	COG1252	NADH dehydrogenase
JNE42_15160	COG0492	ferredoxin-NADP+ reductase activity
JNE42_15175	COG0789	Transcriptional regulator
JNE42_15180	COG5504	Zn-dependent protease
JNE42_15185	COG0316	Belongs to the HesB IscA family
JNE42_15190	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JNE42_15195	COG4844	belongs to the
JNE42_15200	COG1252	NADH dehydrogenase
JNE42_15210	COG4837	Protein of unknown function (DUF1462)
JNE42_15215	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JNE42_15220	COG4946	Tricorn protease homolog
JNE42_15220	COG0823	Involved in the tonB-independent uptake of proteins
JNE42_15220	COG1506	peptidase
JNE42_15225	COG0083	homoserine kinase activity
JNE42_15230	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JNE42_15235	COG0460	homoserine dehydrogenase
JNE42_15240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JNE42_15245	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JNE42_15250	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JNE42_15255	COG0647	UMP catabolic process
JNE42_15260	COG2445	Protein of unknown function DUF86
JNE42_15265	COG4470	Protein conserved in bacteria
JNE42_15275	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JNE42_15280	COG0739	heme binding
JNE42_15300	COG3377	Domain of unknown function (DUF1805)
JNE42_15305	COG0737	Belongs to the 5'-nucleotidase family
JNE42_15310	COG1801	Protein of unknown function DUF72
JNE42_15315	COG2508	Transcriptional regulator
JNE42_15320	COG2140	Oxalate decarboxylase
JNE42_15325	COG2814	Major facilitator Superfamily
JNE42_15330	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JNE42_15335	COG2356	endonuclease I
JNE42_15345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JNE42_15350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JNE42_15355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JNE42_15375	COG0642	Histidine kinase
JNE42_15375	COG5002	protein histidine kinase activity
JNE42_15380	COG0745	RESPONSE REGULATOR receiver
JNE42_15385	COG2311	Membrane
JNE42_15400	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JNE42_15405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JNE42_15410	COG1309	transcriptional regulator
JNE42_15425	COG0719	Fe-S assembly protein
JNE42_15430	COG0822	iron-sulfur transferase activity
JNE42_15435	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JNE42_15440	COG0719	Fe-S assembly protein
JNE42_15445	COG0396	ATPase activity
JNE42_15455	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JNE42_15460	COG1464	Belongs to the NlpA lipoprotein family
JNE42_15465	COG2011	ABC-type metal ion transport system permease component
JNE42_15470	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JNE42_15480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JNE42_15485	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JNE42_15495	COG0509	glycine decarboxylation via glycine cleavage system
JNE42_15500	COG1393	Belongs to the ArsC family
JNE42_15505	COG1960	acyl-CoA dehydrogenase activity
JNE42_15510	COG0183	Belongs to the thiolase family
JNE42_15515	COG1250	3-hydroxyacyl-CoA dehydrogenase
JNE42_15515	COG1024	Enoyl-CoA hydratase
JNE42_15530	COG5577	PFAM Coat F domain
JNE42_15540	COG1120	ATPase activity
JNE42_15550	COG1028	Short-chain dehydrogenase reductase Sdr
JNE42_15555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JNE42_15560	COG0745	RESPONSE REGULATOR receiver
JNE42_15565	COG2770	Histidine kinase
JNE42_15565	COG2205	protein histidine kinase activity
JNE42_15575	COG1309	transcriptional regulator
JNE42_15580	COG0114	fumarate hydratase activity
JNE42_15590	COG0697	spore germination
JNE42_15595	COG0814	amino acid
JNE42_15610	COG2197	response regulator
JNE42_15615	COG4585	Histidine kinase
JNE42_15620	COG4758	membrane
JNE42_15630	COG1842	Phage shock protein A
JNE42_15635	COG4758	membrane
JNE42_15640	COG2096	Adenosyltransferase
JNE42_15645	COG1120	ATPase activity
JNE42_15650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JNE42_15655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JNE42_15665	COG2721	sulfolactate sulfo-lyase activity
JNE42_15670	COG0246	Mannitol dehydrogenase
JNE42_15675	COG1609	Transcriptional regulator
JNE42_15680	COG1904	glucuronate isomerase
JNE42_15685	COG2205	protein histidine kinase activity
JNE42_15690	COG0745	RESPONSE REGULATOR receiver
JNE42_15695	COG1120	ATPase activity
JNE42_15700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JNE42_15705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JNE42_15710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JNE42_15715	COG0531	amino acid
JNE42_15730	COG1988	membrane-bound metal-dependent
JNE42_15735	COG1368	sulfuric ester hydrolase activity
JNE42_15740	COG0725	ABC transporter, periplasmic molybdate-binding protein
JNE42_15745	COG4149	molybdate abc transporter
JNE42_15750	COG0656	L-ascorbic acid biosynthetic process
JNE42_15755	COG1940	carbohydrate kinase activity
JNE42_15760	COG0025	NhaP-type Na H and K H
JNE42_15765	COG2860	membrane
JNE42_15770	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JNE42_15775	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JNE42_15780	COG2217	Heavy metal translocating P-type atpase
JNE42_15785	COG1121	(ABC) transporter
JNE42_15790	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JNE42_15795	COG0803	Belongs to the bacterial solute-binding protein 9 family
JNE42_15805	COG3226	Transcriptional regulator
JNE42_15810	COG0784	Response regulator, receiver
JNE42_15815	COG4191	Histidine kinase
JNE42_15820	COG1027	Aspartate ammonia-lyase
JNE42_15835	COG2217	Heavy metal translocating P-type atpase
JNE42_15840	COG2608	mercury ion transmembrane transporter activity
JNE42_15845	COG1937	Protein conserved in bacteria
JNE42_15865	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JNE42_15875	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
JNE42_15885	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JNE42_15890	COG0557	exoribonuclease II activity
JNE42_15895	COG1647	Serine aminopeptidase, S33
JNE42_15900	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JNE42_15905	COG2002	toxin-antitoxin pair type II binding
JNE42_15910	COG1476	TRANSCRIPTIONal
JNE42_15915	COG1396	sequence-specific DNA binding
JNE42_15920	COG1396	sequence-specific DNA binding
JNE42_15925	COG1733	regulation of RNA biosynthetic process
JNE42_15930	COG1174	glycine betaine transport
JNE42_15935	COG1732	Glycine betaine
JNE42_15940	COG1174	glycine betaine transport
JNE42_15945	COG0517	IMP dehydrogenase activity
JNE42_15945	COG1125	glycine betaine transport
JNE42_15950	COG1510	regulation of RNA biosynthetic process
JNE42_15955	COG2095	MarC family integral membrane protein
JNE42_15965	COG0456	acetyltransferase
JNE42_15985	COG1131	(ABC) transporter
JNE42_15995	COG0148	phosphopyruvate hydratase activity
JNE42_16000	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JNE42_16005	COG0149	triose-phosphate isomerase activity
JNE42_16010	COG0126	phosphoglycerate kinase activity
JNE42_16015	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JNE42_16020	COG2390	Transcriptional regulator
JNE42_16025	COG0833	amino acid
JNE42_16030	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JNE42_16035	COG3829	transcription factor binding
JNE42_16040	COG2186	Transcriptional regulator
JNE42_16045	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JNE42_16055	COG0534	Mate efflux family protein
JNE42_16060	COG4608	Belongs to the ABC transporter superfamily
JNE42_16065	COG0444	Belongs to the ABC transporter superfamily
JNE42_16070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JNE42_16075	COG0601	transmembrane transport
JNE42_16080	COG0747	negative chemotaxis
JNE42_16085	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JNE42_16090	COG0110	maltose O-acetyltransferase activity
JNE42_16095	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JNE42_16100	COG2244	polysaccharide biosynthetic process
JNE42_16105	COG5039	Polysaccharide pyruvyl transferase
JNE42_16110	COG1216	Glycosyl transferase, family 2
JNE42_16120	COG0438	transferase activity, transferring glycosyl groups
JNE42_16125	COG1215	transferase activity, transferring glycosyl groups
JNE42_16130	COG0438	transferase activity, transferring glycosyl groups
JNE42_16135	COG1086	Polysaccharide biosynthesis protein
JNE42_16140	COG0489	protein tyrosine kinase activity
JNE42_16145	COG3944	biosynthesis protein
JNE42_16150	COG1396	sequence-specific DNA binding
JNE42_16160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JNE42_16165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JNE42_16170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JNE42_16175	COG0726	polysaccharide deacetylase
JNE42_16180	COG0488	(ABC) transporter
JNE42_16200	COG0601	transmembrane transport
JNE42_16205	COG0747	negative chemotaxis
JNE42_16210	COG1819	glycosyl
JNE42_16215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JNE42_16230	COG0740	serine-type endopeptidase activity
JNE42_16235	COG1611	Belongs to the LOG family
JNE42_16240	COG1694	Mazg nucleotide pyrophosphohydrolase
JNE42_16245	COG0659	secondary active sulfate transmembrane transporter activity
JNE42_16250	COG0288	reversible hydration of carbon dioxide
JNE42_16255	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JNE42_16265	COG2162	N-hydroxyarylamine O-acetyltransferase activity
JNE42_16270	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JNE42_16275	COG1481	regulation of sporulation
JNE42_16280	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JNE42_16285	COG1660	Displays ATPase and GTPase activities
JNE42_16290	COG1051	belongs to the nudix hydrolase family
JNE42_16295	COG0492	ferredoxin-NADP+ reductase activity
JNE42_16300	COG3883	PFAM NLP P60 protein
JNE42_16300	COG0791	NLP P60 protein
JNE42_16305	COG0457	Tetratricopeptide repeat
JNE42_16310	COG0140	phosphoribosyl-ATP diphosphatase activity
JNE42_16310	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JNE42_16315	COG0107	imidazoleglycerol-phosphate synthase activity
JNE42_16320	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JNE42_16325	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JNE42_16330	COG0131	Imidazoleglycerol-phosphate dehydratase
JNE42_16335	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JNE42_16340	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JNE42_16345	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JNE42_16350	COG4990	cell redox homeostasis
JNE42_16355	COG2910	NAD(P)H-binding
JNE42_16360	COG1959	2 iron, 2 sulfur cluster binding
JNE42_16365	COG0110	maltose O-acetyltransferase activity
JNE42_16370	COG0546	phosphoglycolate phosphatase activity
JNE42_16375	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
JNE42_16380	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JNE42_16385	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JNE42_16390	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JNE42_16395	COG0363	glucosamine-6-phosphate deaminase activity
JNE42_16400	COG2188	Transcriptional regulator
JNE42_16405	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JNE42_16410	COG1950	PFAM Membrane protein of
JNE42_16415	COG1983	PspC domain protein
JNE42_16420	COG3595	metallopeptidase activity
JNE42_16435	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JNE42_16445	COG4897	Protein conserved in bacteria
JNE42_16450	COG3848	Pyruvate phosphate dikinase
JNE42_16450	COG0574	Belongs to the PEP-utilizing enzyme family
JNE42_16455	COG1309	transcriptional regulator
JNE42_16460	COG2814	Major facilitator Superfamily
JNE42_16470	COG0745	RESPONSE REGULATOR receiver
JNE42_16475	COG5002	protein histidine kinase activity
JNE42_16480	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JNE42_16485	COG0463	Glycosyl transferase, family 2
JNE42_16490	COG1113	amino acid transport
JNE42_16495	COG0778	Nitroreductase
JNE42_16500	COG1733	regulation of RNA biosynthetic process
JNE42_16505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JNE42_16515	COG0793	Belongs to the peptidase S41A family
JNE42_16515	COG3409	Peptidoglycan-binding domain 1 protein
JNE42_16520	COG0730	response to heat
JNE42_16525	COG0791	NLP P60 protein
JNE42_16525	COG3883	PFAM NLP P60 protein
JNE42_16530	COG2177	Part of the ABC transporter FtsEX involved in
JNE42_16535	COG2884	Cell division ATP-binding protein ftsE
JNE42_16540	COG2010	Cytochrome c
JNE42_16545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JNE42_16565	COG0653	protein targeting
JNE42_16570	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JNE42_16575	COG0840	transmembrane signaling receptor activity
JNE42_16590	COG1516	flagellar protein fliS
JNE42_16595	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JNE42_16600	COG1334	flagellar protein FlaG
JNE42_16605	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
JNE42_16610	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
JNE42_16620	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JNE42_16625	COG1256	bacterial-type flagellum assembly
JNE42_16625	COG4786	Flagellar basal body rod
JNE42_16630	COG3418	PFAM FlgN family protein
JNE42_16645	COG1040	competence protein
JNE42_16655	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JNE42_16660	COG1307	EDD domain protein, DegV family
JNE42_16665	COG2197	response regulator
JNE42_16670	COG4585	Histidine kinase
JNE42_16675	COG1739	Uncharacterized protein family UPF0029
JNE42_16685	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JNE42_16690	COG0438	transferase activity, transferring glycosyl groups
JNE42_16695	COG1215	transferase activity, transferring glycosyl groups
JNE42_16700	COG3206	protein involved in exopolysaccharide biosynthesis
JNE42_16705	COG3307	-O-antigen
JNE42_16710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JNE42_16715	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JNE42_16720	COG0438	transferase activity, transferring glycosyl groups
JNE42_16720	COG0297	glycogen (starch) synthase activity
JNE42_16725	COG2244	polysaccharide biosynthetic process
JNE42_16740	COG2247	cell wall binding repeat
JNE42_16740	COG0860	N-Acetylmuramoyl-L-alanine amidase
JNE42_16745	COG0860	N-Acetylmuramoyl-L-alanine amidase
JNE42_16745	COG2247	cell wall binding repeat
JNE42_16750	COG2385	sporulation resulting in formation of a cellular spore
JNE42_16750	COG2247	cell wall binding repeat
JNE42_16760	COG1316	TRANSCRIPTIONal
JNE42_16765	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JNE42_16770	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JNE42_16775	COG1134	teichoic acid transport
JNE42_16780	COG1682	transport, permease protein
JNE42_16785	COG1216	Glycosyl transferase, family 2
JNE42_16795	COG1181	Belongs to the D-alanine--D-alanine ligase family
JNE42_16800	COG0463	Glycosyl transferase, family 2
JNE42_16800	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JNE42_16810	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JNE42_16815	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JNE42_16825	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JNE42_16830	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JNE42_16835	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JNE42_16840	COG4193	domain, Protein
JNE42_16845	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JNE42_16850	COG1482	cell wall glycoprotein biosynthetic process
JNE42_16860	COG1175	transmembrane transport
JNE42_16865	COG1653	transport
JNE42_16870	COG2197	response regulator
JNE42_16875	COG2972	Histidine kinase
JNE42_16885	COG0454	-acetyltransferase
JNE42_16890	COG0800	Aldolase
JNE42_16895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JNE42_16900	COG1609	Transcriptional regulator
JNE42_16905	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
JNE42_16910	COG1028	Short-chain dehydrogenase reductase Sdr
JNE42_16915	COG0697	spore germination
JNE42_16920	COG0814	amino acid
JNE42_16935	COG2814	Major facilitator Superfamily
JNE42_16940	COG1316	TRANSCRIPTIONal
JNE42_16945	COG0561	phosphatase activity
JNE42_16950	COG0791	NLP P60 protein
JNE42_16960	COG2843	Capsule synthesis protein
JNE42_16970	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JNE42_16975	COG0697	spore germination
JNE42_16990	COG1609	Transcriptional regulator
JNE42_16995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JNE42_17000	COG1869	D-ribose catabolic process
JNE42_17005	COG1129	ABC transporter
JNE42_17010	COG1172	Belongs to the binding-protein-dependent transport system permease family
JNE42_17015	COG1879	ABC-type sugar transport system periplasmic component
JNE42_17020	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JNE42_17025	COG0583	DNA-binding transcription factor activity
JNE42_17030	COG0028	Belongs to the TPP enzyme family
JNE42_17035	COG3527	Alpha-acetolactate decarboxylase
JNE42_17040	COG1522	sequence-specific DNA binding
JNE42_17045	COG2059	Chromate
JNE42_17050	COG2059	Chromate
JNE42_17055	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JNE42_17065	COG4715	Zinc finger, swim domain protein
JNE42_17070	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JNE42_17075	COG2202	Pas domain
JNE42_17075	COG1366	Belongs to the anti-sigma-factor antagonist family
JNE42_17080	COG0561	phosphatase activity
JNE42_17095	COG1970	mechanosensitive ion channel activity
JNE42_17100	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JNE42_17105	COG0457	Tetratricopeptide repeat
JNE42_17110	COG4786	Flagellar basal body rod
JNE42_17115	COG4786	Flagellar basal body rod
JNE42_17120	COG1077	Cell shape determining protein MreB Mrl
JNE42_17125	COG1609	Transcriptional regulator
JNE42_17130	COG1846	Transcriptional regulator
JNE42_17135	COG2814	Major facilitator Superfamily
JNE42_17140	COG0671	phosphoesterase, PA-phosphatase related
JNE42_17145	COG0477	Major facilitator Superfamily
JNE42_17150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JNE42_17155	COG0765	amino acid transport
JNE42_17160	COG1126	abc transporter atp-binding protein
JNE42_17165	COG0004	ammonium transporteR
JNE42_17170	COG0347	Belongs to the P(II) protein family
JNE42_17175	COG0739	heme binding
JNE42_17180	COG1247	-acetyltransferase
JNE42_17190	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JNE42_17195	COG0523	cobalamin synthesis protein
JNE42_17200	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JNE42_17205	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JNE42_17210	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JNE42_17215	COG2223	nitrite transmembrane transporter activity
JNE42_17220	COG0243	molybdopterin cofactor binding
JNE42_17225	COG2304	oxidoreductase activity
JNE42_17230	COG2304	oxidoreductase activity
JNE42_17235	COG2385	sporulation resulting in formation of a cellular spore
JNE42_17240	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JNE42_17250	COG4836	Membrane
JNE42_17260	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JNE42_17265	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JNE42_17270	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JNE42_17275	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JNE42_17280	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JNE42_17285	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JNE42_17290	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JNE42_17295	COG0356	it plays a direct role in the translocation of protons across the membrane
JNE42_17305	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JNE42_17310	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JNE42_17315	COG4475	Protein of unknown function (DUF436)
JNE42_17320	COG0698	ribose 5-phosphate isomerase
JNE42_17325	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JNE42_17330	COG1971	Probably functions as a manganese efflux pump
JNE42_17335	COG0009	L-threonylcarbamoyladenylate synthase
JNE42_17340	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JNE42_17355	COG2890	protein-(glutamine-N5) methyltransferase activity
JNE42_17360	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JNE42_17365	COG0789	Transcriptional regulator
JNE42_17375	COG0679	Auxin Efflux Carrier
JNE42_17380	COG0281	malic enzyme
JNE42_17385	COG1435	thymidine kinase activity
JNE42_17390	COG0254	rRNA binding
JNE42_17395	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JNE42_17400	COG1494	fructose-1,6-bisphosphatase
JNE42_17405	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JNE42_17410	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JNE42_17415	COG0191	fructose-bisphosphate aldolase activity
JNE42_17420	COG2204	response regulator
JNE42_17425	COG4821	SIS domain
JNE42_17430	COG0504	CTP synthase activity
JNE42_17435	COG3343	RNA polymerase activity
JNE42_17450	COG1960	acyl-CoA dehydrogenase activity
JNE42_17455	COG1960	acyl-CoA dehydrogenase activity
JNE42_17460	COG1250	3-hydroxyacyl-CoA dehydrogenase
JNE42_17465	COG0183	Belongs to the thiolase family
JNE42_17470	COG2181	nitrate reductase activity
JNE42_17470	COG0247	lactate metabolic process
JNE42_17475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JNE42_17480	COG4294	response to UV
JNE42_17490	COG1619	proteins homologs of microcin C7 resistance protein MccF
JNE42_17495	COG1132	(ABC) transporter
JNE42_17500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JNE42_17505	COG1619	proteins homologs of microcin C7 resistance protein MccF
JNE42_17515	COG0018	arginyl-trna synthetase
JNE42_17520	COG4506	Protein conserved in bacteria
JNE42_17530	COG0010	Belongs to the arginase family
JNE42_17535	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JNE42_17540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JNE42_17550	COG1994	Peptidase M50
JNE42_17555	COG1942	4-Oxalocrotonate Tautomerase
JNE42_17565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JNE42_17570	COG0583	DNA-binding transcription factor activity
JNE42_17575	COG0431	NADPH-dependent FMN reductase
JNE42_17580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JNE42_17585	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JNE42_17590	COG0454	-acetyltransferase
JNE42_17595	COG0765	amino acid transport
JNE42_17605	COG0765	amino acid transport
JNE42_17610	COG1126	abc transporter atp-binding protein
JNE42_17615	COG3465	dGTPase activity
JNE42_17620	COG1078	dGTPase activity
JNE42_17625	COG4844	belongs to the
JNE42_17675	COG5444	nuclease activity
JNE42_17715	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JNE42_17725	COG0280	phosphate acetyltransferase
JNE42_17735	COG1073	alpha beta
JNE42_17740	COG1522	sequence-specific DNA binding
JNE42_17745	COG2814	Major facilitator Superfamily
JNE42_17750	COG0077	Prephenate dehydratase
JNE42_17755	COG1917	Cupin 2, conserved barrel domain protein
JNE42_17760	COG1028	Short-chain dehydrogenase reductase Sdr
JNE42_17765	COG0151	Belongs to the GarS family
JNE42_17770	COG0436	Aminotransferase
JNE42_17775	COG1028	Short-chain dehydrogenase reductase Sdr
JNE42_17780	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
JNE42_17785	COG1091	dTDP-4-dehydrorhamnose reductase activity
JNE42_17790	COG1088	dTDP-glucose 4,6-dehydratase activity
JNE42_17795	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JNE42_17800	COG3980	spore coat polysaccharide biosynthesis protein
JNE42_17805	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
JNE42_17810	COG2089	acid synthase
JNE42_17815	COG0456	acetyltransferase
JNE42_17820	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JNE42_17825	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JNE42_17830	COG0463	Glycosyl transferase, family 2
JNE42_17850	COG2363	Small membrane protein
JNE42_17855	COG2233	PERMEase
JNE42_17865	COG1012	belongs to the aldehyde dehydrogenase family
JNE42_17870	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JNE42_17875	COG1216	Glycosyl transferase, family 2
JNE42_17885	COG0351	phosphomethylpyrimidine kinase
JNE42_17900	COG1621	beta-fructofuranosidase activity
JNE42_17905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JNE42_17905	COG1263	PTS System
JNE42_17910	COG3711	transcriptional antiterminator
JNE42_17920	COG1404	Belongs to the peptidase S8 family
JNE42_17930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JNE42_17935	COG0778	Nitroreductase
JNE42_17940	COG0772	Belongs to the SEDS family
JNE42_17950	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JNE42_17955	COG1845	cytochrome c oxidase, subunit III
JNE42_17960	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JNE42_17965	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JNE42_17975	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
JNE42_17980	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JNE42_17985	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JNE42_18000	COG2246	polysaccharide biosynthetic process
JNE42_18025	COG0457	Tetratricopeptide repeat
JNE42_18035	COG3162	membrane
JNE42_18040	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JNE42_18055	COG0352	thiamine-phosphate diphosphorylase activity
JNE42_18060	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JNE42_18065	COG0583	DNA-binding transcription factor activity
JNE42_18070	COG1380	Effector of murein hydrolase LrgA
JNE42_18075	COG1346	cytolysis
JNE42_18080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JNE42_18085	COG0346	lactoylglutathione lyase activity
JNE42_18095	COG0765	amino acid transport
JNE42_18100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JNE42_18105	COG0457	Tetratricopeptide repeat
JNE42_18115	COG2357	RelA SpoT domain protein
JNE42_18120	COG1172	Belongs to the binding-protein-dependent transport system permease family
JNE42_18125	COG1129	ABC transporter
JNE42_18135	COG3420	alginic acid biosynthetic process
JNE42_18140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JNE42_18150	COG1486	melibiose metabolic process
JNE42_18155	COG1447	Phosphotransferase system cellobiose-specific component IIA
JNE42_18160	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JNE42_18165	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JNE42_18170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JNE42_18170	COG3711	transcriptional antiterminator
JNE42_18185	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JNE42_18200	COG1595	DNA-templated transcription, initiation
JNE42_18210	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JNE42_18215	COG4988	ABC transporter
JNE42_18220	COG1294	oxidase, subunit
JNE42_18225	COG1271	oxidase subunit
JNE42_18235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JNE42_18240	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JNE42_18245	COG4509	Sortase family
JNE42_18270	COG5386	Cell surface protein
JNE42_18275	COG5386	Cell surface protein
JNE42_18280	COG1733	regulation of RNA biosynthetic process
JNE42_18285	COG2514	catechol 2,3-dioxygenase activity
JNE42_18290	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JNE42_18290	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JNE42_18295	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JNE42_18295	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JNE42_18305	COG0726	polysaccharide deacetylase
JNE42_18310	COG1447	Phosphotransferase system cellobiose-specific component IIA
JNE42_18315	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JNE42_18320	COG2723	6-phospho-beta-galactosidase activity
JNE42_18325	COG1312	Catalyzes the dehydration of D-mannonate
JNE42_18330	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JNE42_18335	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JNE42_18335	COG3711	transcriptional antiterminator
JNE42_18360	COG1757	Na H antiporter
JNE42_18365	COG1027	Aspartate ammonia-lyase
JNE42_18370	COG0252	asparaginase activity
JNE42_18375	COG1396	sequence-specific DNA binding
JNE42_18400	COG4842	Belongs to the WXG100 family
JNE42_18405	COG2195	Cleaves the N-terminal amino acid of tripeptides
JNE42_18420	COG1737	Transcriptional regulator
JNE42_18425	COG2084	Dehydrogenase
JNE42_18435	COG2610	gluconate transmembrane transporter activity
JNE42_18440	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JNE42_18465	COG2723	6-phospho-beta-galactosidase activity
JNE42_18470	COG2190	(PTS) system
JNE42_18470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JNE42_18470	COG1263	PTS System
JNE42_18475	COG3711	transcriptional antiterminator
JNE42_18480	COG3878	Protein conserved in bacteria
JNE42_18490	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JNE42_18495	COG1122	ATPase activity
JNE42_18500	COG4721	ABC-type cobalt transport system, permease component
JNE42_18505	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JNE42_18540	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
JNE42_18545	COG0778	Nitroreductase
JNE42_18550	COG1846	Transcriptional regulator
JNE42_18555	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JNE42_18560	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JNE42_18565	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JNE42_18570	COG2390	Transcriptional regulator
JNE42_18580	COG2755	lipolytic protein G-D-S-L family
JNE42_18580	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JNE42_18585	COG0477	Major facilitator Superfamily
JNE42_18595	COG2226	methyltransferase
JNE42_18605	COG0561	phosphatase activity
JNE42_18610	COG0789	Transcriptional regulator
JNE42_18615	COG0673	inositol 2-dehydrogenase activity
JNE42_18620	COG0840	transmembrane signaling receptor activity
JNE42_18625	COG1113	amino acid transport
JNE42_18630	COG4335	DNA alkylation repair
JNE42_18640	COG1070	Carbohydrate kinase
JNE42_18645	COG1737	Transcriptional regulator
JNE42_18685	COG0583	DNA-binding transcription factor activity
JNE42_18690	COG1609	Transcriptional regulator
JNE42_18695	COG2182	Extracellular solute-binding protein
JNE42_18700	COG1175	transmembrane transport
JNE42_18705	COG3833	ABC-type maltose transport systems, permease component
JNE42_18715	COG1874	Beta-galactosidase
JNE42_18720	COG2851	Citrate transporter
JNE42_18730	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JNE42_18735	COG1131	(ABC) transporter
JNE42_18740	COG2824	Alkylphosphonate utilization operon protein PhnA
JNE42_18745	COG1929	Belongs to the glycerate kinase type-1 family
JNE42_18750	COG2610	gluconate transmembrane transporter activity
JNE42_18755	COG3835	regulator
JNE42_18760	COG1309	transcriptional regulator
JNE42_18765	COG2814	Major facilitator Superfamily
JNE42_18775	COG1136	(ABC) transporter
JNE42_18780	COG0457	Tetratricopeptide repeat
JNE42_18785	COG3711	transcriptional antiterminator
JNE42_18790	COG2723	6-phospho-beta-galactosidase activity
JNE42_18795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JNE42_18795	COG1263	PTS System
JNE42_18795	COG2190	(PTS) system
JNE42_18820	COG0494	nUDIX hydrolase
JNE42_18835	COG1113	amino acid transport
JNE42_18840	COG1609	Transcriptional regulator
JNE42_18845	COG2814	Major facilitator Superfamily
JNE42_18850	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JNE42_18855	COG2814	Major facilitator Superfamily
JNE42_18875	COG5444	nuclease activity
JNE42_18885	COG2723	6-phospho-beta-galactosidase activity
JNE42_18895	COG2188	Transcriptional regulator
JNE42_18905	COG0384	phenazine biosynthesis protein PhzF
JNE42_18910	COG0583	DNA-binding transcription factor activity
JNE42_18930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JNE42_18945	COG3850	Histidine kinase
JNE42_18945	COG5002	protein histidine kinase activity
JNE42_18950	COG0745	RESPONSE REGULATOR receiver
JNE42_18955	COG2409	Drug exporters of the RND superfamily
JNE42_18960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JNE42_19000	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JNE42_19010	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JNE42_19020	COG4720	Psort location CytoplasmicMembrane, score
JNE42_19040	COG0456	acetyltransferase
JNE42_19045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JNE42_19050	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JNE42_19055	COG4853	Protein conserved in bacteria
JNE42_19060	COG4863	YycH protein
JNE42_19065	COG5002	protein histidine kinase activity
JNE42_19070	COG0745	RESPONSE REGULATOR receiver
JNE42_19095	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JNE42_19105	COG2311	Membrane
JNE42_19110	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JNE42_19115	COG1309	transcriptional regulator
JNE42_19120	COG2124	cytochrome p450
JNE42_19125	COG0346	lactoylglutathione lyase activity
JNE42_19130	COG0305	Participates in initiation and elongation during chromosome replication
JNE42_19155	COG2819	hydrolase of the alpha beta superfamily
JNE42_19160	COG1028	Short-chain dehydrogenase reductase Sdr
JNE42_19165	COG1169	isochorismate synthase
JNE42_19170	COG1021	2,3-dihydroxybenzoate-AMP ligase
JNE42_19175	COG3433	isochorismatase activity
JNE42_19175	COG1535	isochorismatase
JNE42_19180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JNE42_19185	COG3251	PFAM MbtH domain protein
JNE42_19190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JNE42_19190	COG2207	Transcriptional regulator
JNE42_19195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JNE42_19200	COG2819	hydrolase of the alpha beta superfamily
JNE42_19205	COG3093	addiction module antidote protein HigA
JNE42_19210	COG2807	transmembrane transport
JNE42_19215	COG0359	binds to the 23S rRNA
JNE42_19220	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
JNE42_19225	COG4241	membrane
JNE42_19230	COG1227	inorganic diphosphatase activity
JNE42_19240	COG1595	DNA-templated transcription, initiation
JNE42_19250	COG0753	catalase activity
JNE42_19255	COG0655	NAD(P)H dehydrogenase (quinone) activity
JNE42_19260	COG0400	carboxylic ester hydrolase activity
JNE42_19265	COG0346	lactoylglutathione lyase activity
JNE42_19270	COG1174	glycine betaine transport
JNE42_19275	COG0517	IMP dehydrogenase activity
JNE42_19275	COG1125	glycine betaine transport
JNE42_19280	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JNE42_19285	COG0629	single-stranded DNA binding
JNE42_19290	COG0360	Binds together with S18 to 16S ribosomal RNA
JNE42_19295	COG0012	GTP binding
JNE42_19300	COG4481	Protein conserved in bacteria
JNE42_19315	COG3949	Membrane
JNE42_19325	COG1475	DNA binding
JNE42_19330	COG1192	Involved in chromosome partitioning
JNE42_19340	COG1475	DNA binding
JNE42_19345	COG0357	Ribosomal RNA small subunit methyltransferase G
JNE42_19350	COG0445	tRNA wobble uridine modification
JNE42_19355	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JNE42_19360	COG1847	R3H domain protein
JNE42_19365	COG0706	membrane insertase activity
JNE42_19370	COG0594	ribonuclease P activity
JNE42_19375	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JNE42_19410	COG0457	Tetratricopeptide repeat