locus-tag	class	description
NM966_00005	COG0592	DNA-directed DNA polymerase activity
NM966_00010	COG2501	S4 domain
NM966_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NM966_00025	COG0187	DNA topoisomerase II activity
NM966_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NM966_00065	COG0516	GMP reductase activity
NM966_00065	COG0517	IMP dehydrogenase activity
NM966_00070	COG1686	Belongs to the peptidase S11 family
NM966_00075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NM966_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NM966_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NM966_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NM966_00095	COG0840	transmembrane signaling receptor activity
NM966_00105	COG1428	Deoxynucleoside kinase
NM966_00110	COG1428	Deoxynucleoside kinase
NM966_00115	COG1388	LysM domain
NM966_00115	COG3858	chitin binding
NM966_00120	COG1335	isochorismatase
NM966_00125	COG0590	tRNA wobble adenosine to inosine editing
NM966_00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NM966_00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NM966_00145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NM966_00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
NM966_00195	COG3853	Toxic anion resistance protein (TelA)
NM966_00200	COG1982	Orn Lys Arg decarboxylase major
NM966_00205	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NM966_00210	COG3870	Protein conserved in bacteria
NM966_00215	COG1728	Protein conserved in bacteria
NM966_00220	COG0470	DNA polymerase III
NM966_00225	COG1774	PSP1 C-terminal conserved region
NM966_00230	COG4467	Involved in initiation control of chromosome replication
NM966_00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NM966_00240	COG2827	Endonuclease containing a URI domain
NM966_00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NM966_00250	COG2002	toxin-antitoxin pair type II binding
NM966_00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NM966_00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NM966_00260	COG0084	hydrolase, TatD family'
NM966_00265	COG3583	domain protein
NM966_00265	COG3584	3D domain protein
NM966_00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NM966_00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NM966_00285	COG4466	Protein conserved in bacteria
NM966_00295	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NM966_00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NM966_00305	COG0251	oxidation-reduction process
NM966_00310	COG2088	sporulation resulting in formation of a cellular spore
NM966_00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NM966_00325	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NM966_00330	COG0193	aminoacyl-tRNA hydrolase activity
NM966_00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NM966_00345	COG2002	toxin-antitoxin pair type II binding
NM966_00350	COG2244	polysaccharide biosynthetic process
NM966_00355	COG3956	TIGRFAM MazG family protein
NM966_00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NM966_00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NM966_00380	COG1098	S1 RNA binding domain
NM966_00395	COG2208	phosphoserine phosphatase activity
NM966_00400	COG2304	oxidoreductase activity
NM966_00405	COG0515	serine threonine protein kinase
NM966_00410	COG0037	tRNA processing
NM966_00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NM966_00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NM966_00425	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NM966_00430	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NM966_00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NM966_00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NM966_00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NM966_00450	COG0512	Glutamine amidotransferase of anthranilate synthase
NM966_00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NM966_00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NM966_00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NM966_00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NM966_00475	COG1396	sequence-specific DNA binding
NM966_00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NM966_00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NM966_00565	COG4463	regulation of RNA biosynthetic process
NM966_00570	COG3880	PFAM UvrB UvrC protein
NM966_00575	COG3869	Catalyzes the specific phosphorylation of arginine residues in
NM966_00580	COG0542	response to heat
NM966_00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NM966_00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NM966_00595	COG4956	integral membrane protein (PIN domain superfamily)
NM966_00600	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NM966_00605	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NM966_00610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NM966_00615	COG1045	serine acetyltransferase
NM966_00620	COG0215	cysteine-tRNA ligase activity
NM966_00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NM966_00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NM966_00635	COG3688	RNA-binding protein containing a PIN domain
NM966_00640	COG1595	DNA-templated transcription, initiation
NM966_00645	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NM966_00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NM966_00655	COG0250	Participates in transcription elongation, termination and antitermination
NM966_00665	COG0081	regulation of translation
NM966_00670	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NM966_00675	COG0222	ribosome binding
NM966_00680	COG2813	Specifically methylates the guanine in position
NM966_00685	COG0085	RNA polymerase activity
NM966_00690	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NM966_00695	COG1358	cellular component organization or biogenesis
NM966_00700	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NM966_00705	COG0049	tRNA binding
NM966_00710	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NM966_00715	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NM966_00720	COG0596	Alpha beta hydrolase
NM966_00730	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NM966_00735	COG0088	Forms part of the polypeptide exit tunnel
NM966_00740	COG0089	rRNA binding
NM966_00745	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NM966_00750	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NM966_00755	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NM966_00760	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NM966_00765	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NM966_00770	COG0255	Belongs to the universal ribosomal protein uL29 family
NM966_00775	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NM966_00780	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NM966_00785	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NM966_00790	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NM966_00795	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NM966_00800	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NM966_00805	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NM966_00810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NM966_00815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NM966_00820	COG1841	ribosomal large subunit assembly
NM966_00825	COG0200	Binds to the 23S rRNA
NM966_00830	COG0201	protein transport
NM966_00835	COG0563	adenylate kinase activity
NM966_00840	COG0024	Methionine aminopeptidase
NM966_00850	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NM966_00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NM966_00860	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NM966_00865	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NM966_00870	COG0202	RNA polymerase activity
NM966_00875	COG0203	ribosomal protein L17
NM966_00880	COG1122	ATPase activity
NM966_00885	COG1122	ATPase activity
NM966_00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NM966_00895	COG0101	tRNA pseudouridine synthase activity
NM966_00900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NM966_00905	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NM966_00925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NM966_00955	COG0860	N-Acetylmuramoyl-L-alanine amidase
NM966_00960	COG0489	protein tyrosine kinase activity
NM966_00970	COG2194	sulfuric ester hydrolase activity
NM966_00975	COG0726	polysaccharide deacetylase
NM966_01005	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NM966_01010	COG0659	secondary active sulfate transmembrane transporter activity
NM966_01015	COG0385	Bile acid
NM966_01020	COG3876	Protein conserved in bacteria
NM966_01025	COG1472	Belongs to the glycosyl hydrolase 3 family
NM966_01030	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NM966_01035	COG1263	PTS System
NM966_01035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NM966_01040	COG1737	Transcriptional regulator
NM966_01045	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NM966_01080	COG1595	DNA-templated transcription, initiation
NM966_01085	COG5662	AntiSigma factor
NM966_01090	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NM966_01095	COG4856	YbbR-like protein
NM966_01100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NM966_01105	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NM966_01120	COG1131	(ABC) transporter
NM966_01130	COG0577	efflux transmembrane transporter activity
NM966_01130	COG1136	(ABC) transporter
NM966_01140	COG1695	Transcriptional regulator
NM966_01150	COG1131	(ABC) transporter
NM966_01160	COG1413	lyase activity
NM966_01165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NM966_01185	COG1131	(ABC) transporter
NM966_01235	COG2311	Membrane
NM966_01255	COG1476	TRANSCRIPTIONal
NM966_01265	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NM966_01270	COG2207	Transcriptional regulator
NM966_01275	COG1309	transcriptional regulator
NM966_01290	COG1113	amino acid transport
NM966_01295	COG0584	glycerophosphoryl diester phosphodiesterase
NM966_01300	COG2271	Major facilitator Superfamily
NM966_01310	COG1331	Highly conserved protein containing a thioredoxin domain
NM966_01320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NM966_01335	COG0640	Transcriptional regulator
NM966_01350	COG1937	Protein conserved in bacteria
NM966_01355	COG2210	Belongs to the sulfur carrier protein TusA family
NM966_01365	COG0425	Belongs to the sulfur carrier protein TusA family
NM966_01365	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NM966_01370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NM966_01370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NM966_01375	COG0425	Belongs to the sulfur carrier protein TusA family
NM966_01380	COG0730	response to heat
NM966_01390	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NM966_01395	COG2814	Major facilitator Superfamily
NM966_01410	COG1846	Transcriptional regulator
NM966_01415	COG1683	Conserved Protein
NM966_01420	COG0656	L-ascorbic acid biosynthetic process
NM966_01425	COG0371	Dehydrogenase
NM966_01430	COG1054	Belongs to the UPF0176 family
NM966_01435	COG0531	amino acid
NM966_01445	COG3711	transcriptional antiterminator
NM966_01450	COG2190	(PTS) system
NM966_01450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NM966_01450	COG1263	PTS System
NM966_01455	COG2723	6-phospho-beta-galactosidase activity
NM966_01470	COG3711	transcriptional antiterminator
NM966_01470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NM966_01475	COG1940	carbohydrate kinase activity
NM966_01480	COG0383	alpha-mannosidase activity
NM966_01485	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NM966_01490	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NM966_01495	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NM966_01495	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NM966_01500	COG1404	Belongs to the peptidase S8 family
NM966_01515	COG0833	amino acid
NM966_01520	COG2040	homocysteine
NM966_01525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NM966_01545	COG2814	Major facilitator Superfamily
NM966_01550	COG0456	acetyltransferase
NM966_01565	COG1404	Belongs to the peptidase S8 family
NM966_01575	COG1309	transcriptional regulator
NM966_01580	COG1917	Cupin 2, conserved barrel domain protein
NM966_01585	COG1063	alcohol dehydrogenase
NM966_01590	COG1846	Transcriptional regulator
NM966_01595	COG0318	PFAM AMP-dependent synthetase and ligase
NM966_01600	COG0531	amino acid
NM966_01610	COG0596	Alpha beta hydrolase
NM966_01615	COG1115	amino acid carrier protein
NM966_01620	COG2066	Belongs to the glutaminase family
NM966_01625	COG4191	Histidine kinase
NM966_01630	COG0784	Response regulator, receiver
NM966_01635	COG1405	negative regulation of cell septum assembly
NM966_01635	COG3012	SEC-C Motif Domain Protein
NM966_01645	COG0667	Aldo Keto reductase
NM966_01650	COG3290	protein histidine kinase activity
NM966_01655	COG3279	Response regulator of the LytR AlgR family
NM966_01660	COG4555	ABC transporter
NM966_01665	COG1668	transmembrane transport
NM966_01685	COG3773	Cell wall hydrolase
NM966_01690	COG1028	Short-chain dehydrogenase reductase Sdr
NM966_01700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NM966_01705	COG2310	stress, protein
NM966_01710	COG2310	stress, protein
NM966_01715	COG2310	stress, protein
NM966_01720	COG0861	Integral membrane protein TerC family
NM966_01750	COG3853	Toxic anion resistance protein (TelA)
NM966_01755	COG0517	IMP dehydrogenase activity
NM966_01755	COG4175	Glycine betaine
NM966_01760	COG4176	ABC-type proline glycine betaine transport system permease component
NM966_01765	COG2113	Glycine betaine
NM966_01780	COG1473	amidohydrolase
NM966_01785	COG1288	antiporter activity
NM966_01790	COG0039	L-malate dehydrogenase activity
NM966_01795	COG1620	l-lactate permease
NM966_01800	COG1609	Transcriptional regulator
NM966_01805	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NM966_01810	COG0561	phosphatase activity
NM966_01815	COG0673	inositol 2-dehydrogenase activity
NM966_01820	COG0738	Major facilitator superfamily
NM966_01825	COG1280	lysine exporter protein (LysE YggA)
NM966_01840	COG3403	YqcI/YcgG family
NM966_01845	COG1113	amino acid transport
NM966_01850	COG3665	Urea carboxylase-associated protein
NM966_01855	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NM966_01865	COG1012	belongs to the aldehyde dehydrogenase family
NM966_01870	COG0710	3-dehydroquinate dehydratase activity
NM966_01875	COG0028	Belongs to the TPP enzyme family
NM966_01885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NM966_01890	COG2271	Major facilitator Superfamily
NM966_01905	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NM966_01910	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NM966_01920	COG0477	Major facilitator Superfamily
NM966_01925	COG2226	methyltransferase
NM966_01930	COG0583	DNA-binding transcription factor activity
NM966_01935	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NM966_01940	COG3458	cephalosporin-C deacetylase activity
NM966_01950	COG3541	Predicted nucleotidyltransferase
NM966_01955	COG0506	proline dehydrogenase activity
NM966_01960	COG1012	belongs to the aldehyde dehydrogenase family
NM966_01965	COG2508	Transcriptional regulator
NM966_01970	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NM966_01975	COG0765	amino acid transport
NM966_01980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NM966_01990	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NM966_01995	COG1522	sequence-specific DNA binding
NM966_02000	COG2746	aminoglycoside 3-N-acetyltransferase activity
NM966_02010	COG0840	transmembrane signaling receptor activity
NM966_02010	COG3290	protein histidine kinase activity
NM966_02015	COG3209	COG3209 Rhs family protein
NM966_02035	COG3842	ATPase activity
NM966_02040	COG1176	ABC-type spermidine putrescine transport system, permease component I
NM966_02050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM966_02055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM966_02060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM966_02075	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
NM966_02090	COG4555	ABC transporter
NM966_02105	COG0697	spore germination
NM966_02110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NM966_02120	COG2207	Transcriptional regulator
NM966_02120	COG3708	Transcriptional regulator
NM966_02130	COG2364	Membrane
NM966_02135	COG1126	abc transporter atp-binding protein
NM966_02140	COG0765	amino acid transport
NM966_02145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NM966_02150	COG0412	Dienelactone hydrolase
NM966_02155	COG0833	amino acid
NM966_02160	COG3104	oligopeptide transport
NM966_02165	COG5434	Belongs to the glycosyl hydrolase 28 family
NM966_02170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NM966_02175	COG0456	acetyltransferase
NM966_02180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NM966_02185	COG0765	amino acid transport
NM966_02190	COG1126	abc transporter atp-binding protein
NM966_02195	COG1473	amidohydrolase
NM966_02200	COG2079	MmgE PrpD family protein
NM966_02210	COG0745	RESPONSE REGULATOR receiver
NM966_02215	COG5002	protein histidine kinase activity
NM966_02215	COG3850	Histidine kinase
NM966_02220	COG1366	Belongs to the anti-sigma-factor antagonist family
NM966_02225	COG0527	aspartate kinase activity
NM966_02230	COG2814	Major facilitator Superfamily
NM966_02235	COG1309	transcriptional regulator
NM966_02245	COG0640	Transcriptional regulator
NM966_02255	COG0583	DNA-binding transcription factor activity
NM966_02260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NM966_02265	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NM966_02270	COG0531	amino acid
NM966_02275	COG1012	belongs to the aldehyde dehydrogenase family
NM966_02280	COG2249	NAD(P)H dehydrogenase (quinone) activity
NM966_02285	COG4549	nuclear export factor GLE1
NM966_02290	COG1276	copper resistance
NM966_02290	COG2372	response to copper ion
NM966_02295	COG2213	PTS system mannitol-specific
NM966_02300	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NM966_02305	COG0246	Mannitol dehydrogenase
NM966_02310	COG0840	transmembrane signaling receptor activity
NM966_02345	COG0346	lactoylglutathione lyase activity
NM966_02355	COG0561	phosphatase activity
NM966_02360	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NM966_02365	COG1914	H( )-stimulated, divalent metal cation uptake system
NM966_02370	COG4336	lyase activity
NM966_02375	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NM966_02380	COG1984	allophanate hydrolase subunit 2
NM966_02385	COG1414	Transcriptional regulator
NM966_02390	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NM966_02395	COG2755	lipolytic protein G-D-S-L family
NM966_02405	COG3711	transcriptional antiterminator
NM966_02410	COG2226	methyltransferase
NM966_02415	COG1028	Short-chain dehydrogenase reductase Sdr
NM966_02420	COG3871	stress protein (general stress protein 26)
NM966_02440	COG2814	Major facilitator Superfamily
NM966_02445	COG1802	Transcriptional regulator
NM966_02450	COG1917	Cupin 2, conserved barrel domain protein
NM966_02450	COG2207	Transcriptional regulator
NM966_02455	COG0697	spore germination
NM966_02460	COG0473	3-isopropylmalate dehydrogenase activity
NM966_02465	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NM966_02465	COG0551	DNA topoisomerase type I activity
NM966_02470	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
NM966_02475	COG3706	GGDEF domain
NM966_02480	COG5298	Protein conserved in bacteria
NM966_02485	COG1215	transferase activity, transferring glycosyl groups
NM966_02495	COG0531	amino acid
NM966_02500	COG0028	Belongs to the TPP enzyme family
NM966_02505	COG5444	nuclease activity
NM966_02535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NM966_02540	COG1914	H( )-stimulated, divalent metal cation uptake system
NM966_02545	COG2261	transglycosylase associated protein
NM966_02550	COG2217	Heavy metal translocating P-type atpase
NM966_02555	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NM966_02560	COG3290	protein histidine kinase activity
NM966_02565	COG4565	transcriptional regulatory protein
NM966_02570	COG1301	dicarboxylic acid transport
NM966_02575	COG0628	permease
NM966_02580	COG1301	dicarboxylic acid transport
NM966_02585	COG1131	(ABC) transporter
NM966_02590	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NM966_02605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NM966_02610	COG1181	Belongs to the D-alanine--D-alanine ligase family
NM966_02615	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NM966_02630	COG0513	Belongs to the DEAD box helicase family
NM966_02635	COG3402	PFAM membrane-flanked domain
NM966_02640	COG3428	Bacterial PH domain
NM966_02645	COG0705	Rhomboid family
NM966_02650	COG0736	holo-[acyl-carrier-protein] synthase activity
NM966_02655	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NM966_02660	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NM966_02665	COG0864	Transcriptional regulator
NM966_02670	COG2337	Toxic component of a toxin-antitoxin (TA) module
NM966_02675	COG1366	Belongs to the anti-sigma-factor antagonist family
NM966_02680	COG1366	Belongs to the anti-sigma-factor antagonist family
NM966_02685	COG2172	sigma factor antagonist activity
NM966_02690	COG2208	phosphoserine phosphatase activity
NM966_02695	COG1366	Belongs to the anti-sigma-factor antagonist family
NM966_02700	COG2172	sigma factor antagonist activity
NM966_02705	COG1191	sigma factor activity
NM966_02710	COG2208	phosphoserine phosphatase activity
NM966_02715	COG2183	response to ionizing radiation
NM966_02725	COG3091	SprT-like family
NM966_02730	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NM966_02735	COG0022	dehydrogenase e1 component
NM966_02740	COG0508	dehydrogenase complex catalyzes the overall conversion of
NM966_02745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NM966_02750	COG3284	Transcriptional regulator
NM966_02795	COG1278	Cold shock
NM966_02800	COG2190	(PTS) system
NM966_02800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NM966_02800	COG1263	PTS System
NM966_02805	COG3394	polysaccharide catabolic process
NM966_02810	COG3711	transcriptional antiterminator
NM966_02815	COG1064	alcohol dehydrogenase
NM966_02820	COG0789	Transcriptional regulator
NM966_02840	COG0477	Major facilitator Superfamily
NM966_02845	COG0657	acetylesterase activity
NM966_02855	COG4221	oxidoreductase activity
NM966_02865	COG0252	asparaginase activity
NM966_02870	COG2267	carboxylic ester hydrolase activity
NM966_02885	COG2814	Major facilitator Superfamily
NM966_02930	COG1309	transcriptional regulator
NM966_02935	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NM966_02940	COG1846	Transcriptional regulator
NM966_02945	COG0778	Nitroreductase
NM966_02960	COG1396	sequence-specific DNA binding
NM966_02970	COG0456	acetyltransferase
NM966_02980	COG4122	O-methyltransferase activity
NM966_02990	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NM966_02995	COG0697	spore germination
NM966_03005	COG1301	dicarboxylic acid transport
NM966_03045	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NM966_03050	COG0802	atpase or kinase
NM966_03055	COG1214	PFAM Peptidase M22, glycoprotease
NM966_03060	COG0456	acetyltransferase
NM966_03065	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NM966_03070	COG0488	(ABC) transporter
NM966_03075	COG0315	cyclic pyranopterin monophosphate synthase activity
NM966_03080	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NM966_03085	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NM966_03090	COG0805	protein transport
NM966_03105	COG1266	CAAX protease self-immunity
NM966_03110	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NM966_03115	COG0459	protein refolding
NM966_03120	COG1846	Transcriptional regulator
NM966_03125	COG2808	Putative FMN-binding domain
NM966_03130	COG1876	peptidase activity
NM966_03155	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NM966_03160	COG0823	Involved in the tonB-independent uptake of proteins
NM966_03170	COG2132	Multicopper oxidase
NM966_03175	COG1113	amino acid transport
NM966_03180	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NM966_03185	COG0714	Associated with various cellular activities
NM966_03190	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
NM966_03195	COG1305	Transglutaminase-like
NM966_03200	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NM966_03200	COG0519	Catalyzes the synthesis of GMP from XMP
NM966_03210	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NM966_03220	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NM966_03225	COG2207	Transcriptional regulator
NM966_03260	COG1595	DNA-templated transcription, initiation
NM966_03270	COG2814	Major facilitator Superfamily
NM966_03275	COG0583	DNA-binding transcription factor activity
NM966_03280	COG2252	PERMEase
NM966_03290	COG5583	Uncharacterized small protein (DUF2292)
NM966_03295	COG3064	Membrane
NM966_03300	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
NM966_03310	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NM966_03315	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NM966_03320	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NM966_03325	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NM966_03330	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NM966_03335	COG0047	phosphoribosylformylglycinamidine synthase activity
NM966_03340	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NM966_03345	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NM966_03350	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NM966_03355	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NM966_03360	COG0138	bifunctional purine biosynthesis protein purh
NM966_03365	COG0151	Belongs to the GarS family
NM966_03385	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NM966_03390	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NM966_03395	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NM966_03400	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NM966_03410	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NM966_03415	COG4496	protein, YerC YecD
NM966_03425	COG0069	glutamate synthase activity
NM966_03440	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NM966_03445	COG0210	DNA helicase
NM966_03450	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NM966_03455	COG4851	CamS sex pheromone cAM373 precursor
NM966_03460	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NM966_03465	COG1285	pathogenesis
NM966_03470	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NM966_03475	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NM966_03480	COG0154	amidase activity
NM966_03485	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NM966_03490	COG1309	transcriptional regulator
NM966_03495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NM966_03500	COG1957	nucleoside hydrolase
NM966_03505	COG1597	lipid kinase activity
NM966_03510	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NM966_03530	COG0457	Tetratricopeptide repeat
NM966_03535	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NM966_03550	COG1959	2 iron, 2 sulfur cluster binding
NM966_03555	COG0492	ferredoxin-NADP+ reductase activity
NM966_03570	COG1486	melibiose metabolic process
NM966_03580	COG2211	Major facilitator Superfamily
NM966_03620	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NM966_03625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NM966_03630	COG1442	glycosyl transferase family 8
NM966_03635	COG1216	Glycosyl transferase, family 2
NM966_03640	COG1442	glycosyl transferase family 8
NM966_03645	COG2223	nitrite transmembrane transporter activity
NM966_03655	COG0471	metal ion transport
NM966_03670	COG0071	Belongs to the small heat shock protein (HSP20) family
NM966_03685	COG0531	amino acid
NM966_03690	COG0457	Tetratricopeptide repeat
NM966_03690	COG0463	Glycosyl transferase, family 2
NM966_03695	COG0488	(ABC) transporter
NM966_03700	COG1469	GTP cyclohydrolase I activity
NM966_03705	COG0789	Transcriptional regulator
NM966_03710	COG2814	Major facilitator Superfamily
NM966_03715	COG0488	(ABC) transporter
NM966_03720	COG0513	Belongs to the DEAD box helicase family
NM966_03725	COG2130	NADP-dependent
NM966_03745	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NM966_03745	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NM966_03750	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NM966_03760	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NM966_03760	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NM966_03770	COG3290	protein histidine kinase activity
NM966_03775	COG4565	transcriptional regulatory protein
NM966_03780	COG3181	Tripartite tricarboxylate transporter family receptor
NM966_03785	COG2851	Citrate transporter
NM966_03795	COG3479	Phenolic acid decarboxylase
NM966_03800	COG1695	Transcriptional regulator
NM966_03805	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NM966_03815	COG1254	Belongs to the acylphosphatase family
NM966_03820	COG2258	MOSC domain
NM966_03835	COG0024	Methionine aminopeptidase
NM966_03840	COG1263	PTS System
NM966_03840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NM966_03845	COG3739	integral membrane protein
NM966_03860	COG1368	sulfuric ester hydrolase activity
NM966_03865	COG0076	glutamate decarboxylase activity
NM966_03870	COG0840	transmembrane signaling receptor activity
NM966_03880	COG1263	PTS System
NM966_03880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NM966_03885	COG0366	Alpha amylase catalytic
NM966_03890	COG2188	Transcriptional regulator
NM966_03900	COG0737	Belongs to the 5'-nucleotidase family
NM966_03905	COG0693	protein deglycase activity
NM966_03910	COG4840	Belongs to the UPF0435 family
NM966_03915	COG1115	amino acid carrier protein
NM966_03920	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NM966_03925	COG4980	gas vesicle protein
NM966_03930	COG1295	ribonuclease BN
NM966_03935	COG0477	Major facilitator Superfamily
NM966_03945	COG0387	Pfam Sodium calcium exchanger
NM966_03955	COG0217	transcriptional regulatory protein
NM966_03965	COG0668	transmembrane transport
NM966_03970	COG0535	radical SAM domain protein
NM966_03980	COG0726	polysaccharide deacetylase
NM966_03990	COG0598	Magnesium transport protein CorA
NM966_04000	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NM966_04005	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NM966_04035	COG0789	Transcriptional regulator
NM966_04040	COG2814	Major facilitator Superfamily
NM966_04055	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NM966_04100	COG2076	Multidrug Resistance protein
NM966_04105	COG2076	Multidrug Resistance protein
NM966_04110	COG1309	transcriptional regulator
NM966_04120	COG4637	Psort location Cytoplasmic, score
NM966_04125	COG2755	lipolytic protein G-D-S-L family
NM966_04130	COG0492	ferredoxin-NADP+ reductase activity
NM966_04135	COG2169	Transcriptional regulator
NM966_04140	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NM966_04145	COG1132	(ABC) transporter
NM966_04150	COG1742	UPF0060 membrane protein
NM966_04155	COG1595	DNA-templated transcription, initiation
NM966_04175	COG2318	DinB family
NM966_04185	COG1846	Transcriptional regulator
NM966_04190	COG0392	lysyltransferase activity
NM966_04190	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NM966_04210	COG0778	Nitroreductase
NM966_04225	COG1090	epimerase
NM966_04230	COG2137	regulation of response to DNA damage stimulus
NM966_04255	COG0463	Glycosyl transferase, family 2
NM966_04260	COG4485	Bacterial membrane protein, YfhO
NM966_04265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NM966_04280	COG2140	Oxalate decarboxylase
NM966_04290	COG1191	sigma factor activity
NM966_04300	COG1988	membrane-bound metal-dependent
NM966_04305	COG1194	a g-specific adenine glycosylase
NM966_04315	COG1028	Short-chain dehydrogenase reductase Sdr
NM966_04330	COG3557	Belongs to the UPF0374 family
NM966_04335	COG1132	(ABC) transporter
NM966_04340	COG0444	Belongs to the ABC transporter superfamily
NM966_04345	COG4608	Belongs to the ABC transporter superfamily
NM966_04350	COG0747	negative chemotaxis
NM966_04355	COG0601	transmembrane transport
NM966_04360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NM966_04365	COG4129	membrane
NM966_04370	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NM966_04375	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NM966_04380	COG0735	belongs to the Fur family
NM966_04530	COG1368	sulfuric ester hydrolase activity
NM966_04535	COG0681	Belongs to the peptidase S26 family
NM966_04540	COG2873	o-acetylhomoserine
NM966_04550	COG1116	anion transmembrane transporter activity
NM966_04555	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NM966_04560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NM966_04565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NM966_04580	COG1131	(ABC) transporter
NM966_04610	COG3382	B3 4 domain protein
NM966_04615	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NM966_04625	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NM966_04630	COG2766	serine protein kinase
NM966_04635	COG2718	Belongs to the UPF0229 family
NM966_04640	COG1566	PFAM secretion protein HlyD family protein
NM966_04645	COG2814	Major facilitator Superfamily
NM966_04650	COG0655	NAD(P)H dehydrogenase (quinone) activity
NM966_04660	COG1278	Cold shock
NM966_04665	COG3706	GGDEF domain
NM966_04690	COG5577	PFAM Coat F domain
NM966_04695	COG5002	protein histidine kinase activity
NM966_04700	COG0737	Belongs to the 5'-nucleotidase family
NM966_04700	COG1525	nuclease
NM966_04700	COG4085	toxin activity
NM966_04705	COG3764	Sortase (surface protein transpeptidase)
NM966_04710	COG0564	pseudouridine synthase activity
NM966_04720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NM966_04725	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NM966_04725	COG3153	acetyltransferase
NM966_04745	COG3835	regulator
NM966_04750	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NM966_04755	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NM966_04760	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NM966_04765	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NM966_04770	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NM966_04775	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NM966_04780	COG2203	Gaf domain
NM966_04780	COG4585	Histidine kinase
NM966_04785	COG2197	response regulator
NM966_04800	COG0753	catalase activity
NM966_04805	COG1959	2 iron, 2 sulfur cluster binding
NM966_04810	COG1017	nitric oxide dioxygenase activity
NM966_04810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NM966_04815	COG2719	SpoVR family
NM966_04820	COG1785	Belongs to the alkaline phosphatase family
NM966_04825	COG0791	NLP P60 protein
NM966_04825	COG1388	LysM domain
NM966_04830	COG0531	amino acid
NM966_04845	COG1595	DNA-templated transcription, initiation
NM966_04850	COG0204	Acyl-transferase
NM966_04855	COG1253	flavin adenine dinucleotide binding
NM966_04860	COG0789	Transcriptional regulator
NM966_04865	COG1253	flavin adenine dinucleotide binding
NM966_04880	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NM966_04885	COG0584	glycerophosphoryl diester phosphodiesterase
NM966_04895	COG0668	transmembrane transport
NM966_04900	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NM966_04905	COG0726	polysaccharide deacetylase
NM966_04910	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NM966_04915	COG0589	response to stress
NM966_04920	COG1132	(ABC) transporter
NM966_04925	COG1132	(ABC) transporter
NM966_04930	COG0702	epimerase
NM966_04940	COG3842	ATPase activity
NM966_04945	COG2508	Transcriptional regulator
NM966_04955	COG0189	ligase activity
NM966_04960	COG0189	ligase activity
NM966_04965	COG4399	Belongs to the UPF0754 family
NM966_04970	COG3679	Belongs to the UPF0342 family
NM966_04975	COG0561	phosphatase activity
NM966_04980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NM966_04990	COG0475	glutathione-regulated potassium exporter activity
NM966_04995	COG0490	domain, Protein
NM966_05005	COG1024	Enoyl-CoA hydratase
NM966_05015	COG0420	3'-5' exonuclease activity
NM966_05020	COG4717	serine-type aminopeptidase activity
NM966_05025	COG3481	metal-dependent phosphohydrolase, HD sub domain
NM966_05035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NM966_05065	COG1846	Transcriptional regulator
NM966_05070	COG4980	gas vesicle protein
NM966_05085	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NM966_05090	COG0537	adenosine 5'-monophosphoramidase activity
NM966_05095	COG1131	(ABC) transporter
NM966_05100	COG4473	ABC transporter
NM966_05110	COG1473	amidohydrolase
NM966_05120	COG2329	Antibiotic biosynthesis monooxygenase
NM966_05125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NM966_05130	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NM966_05135	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NM966_05140	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NM966_05145	COG1309	transcriptional regulator
NM966_05150	COG1511	domain protein
NM966_05155	COG1363	Peptidase, m42
NM966_05160	COG1301	dicarboxylic acid transport
NM966_05170	COG1234	tRNA 3'-trailer cleavage
NM966_05175	COG0095	Lipoate-protein ligase
NM966_05180	COG0318	PFAM AMP-dependent synthetase and ligase
NM966_05190	COG0501	Belongs to the peptidase M48B family
NM966_05195	COG1404	Belongs to the peptidase S8 family
NM966_05200	COG0406	alpha-ribazole phosphatase activity
NM966_05205	COG0840	transmembrane signaling receptor activity
NM966_05210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NM966_05210	COG0723	plastoquinol--plastocyanin reductase activity
NM966_05215	COG1028	Short-chain dehydrogenase reductase Sdr
NM966_05225	COG4903	ComK protein
NM966_05240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NM966_05245	COG2814	Major facilitator Superfamily
NM966_05250	COG2732	(Barnase) inhibitor
NM966_05255	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NM966_05260	COG4605	iron ion homeostasis
NM966_05265	COG4604	ABC transporter, ATP-binding protein
NM966_05270	COG4607	ABC-type enterochelin transport system periplasmic component
NM966_05275	COG1316	TRANSCRIPTIONal
NM966_05290	COG0398	Pfam SNARE associated Golgi protein
NM966_05295	COG0681	Belongs to the peptidase S26 family
NM966_05300	COG3180	Ammonia monooxygenase
NM966_05315	COG2259	Doxx family
NM966_05320	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
NM966_05325	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NM966_05330	COG1074	ATP-dependent DNA helicase activity
NM966_05335	COG0420	3'-5' exonuclease activity
NM966_05340	COG0419	ATPase involved in DNA repair
NM966_05345	COG1403	HNH endonuclease
NM966_05385	COG5337	Spore coat protein CotH
NM966_05395	COG0179	Fumarylacetoacetate (FAA) hydrolase
NM966_05410	COG0367	asparagine synthase
NM966_05425	COG1562	ergosterol biosynthetic process
NM966_05430	COG0534	Mate efflux family protein
NM966_05435	COG1917	Cupin 2, conserved barrel domain protein
NM966_05435	COG2207	Transcriptional regulator
NM966_05460	COG0076	glutamate decarboxylase activity
NM966_05495	COG0646	methionine synthase
NM966_05495	COG1410	methionine synthase
NM966_05500	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NM966_05500	COG0646	methionine synthase
NM966_05505	COG1666	GTP binding
NM966_05510	COG2996	Protein conserved in bacteria
NM966_05515	COG1744	ABC transporter substrate-binding protein PnrA-like
NM966_05520	COG0840	transmembrane signaling receptor activity
NM966_05525	COG1307	EDD domain protein, DegV family
NM966_05530	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NM966_05550	COG0561	phosphatase activity
NM966_05555	COG1073	alpha beta
NM966_05560	COG2151	metal-sulfur cluster biosynthetic enzyme
NM966_05565	COG0277	FAD linked oxidase domain protein
NM966_05570	COG2271	Major facilitator Superfamily
NM966_05575	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NM966_05580	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NM966_05585	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NM966_05590	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NM966_05595	COG0505	Belongs to the CarA family
NM966_05600	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NM966_05605	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NM966_05615	COG2814	Major facilitator Superfamily
NM966_05625	COG2267	carboxylic ester hydrolase activity
NM966_05635	COG1744	ABC transporter substrate-binding protein PnrA-like
NM966_05650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NM966_05655	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NM966_05660	COG5504	Zn-dependent protease
NM966_05665	COG0444	Belongs to the ABC transporter superfamily
NM966_05670	COG4608	Belongs to the ABC transporter superfamily
NM966_05680	COG0601	transmembrane transport
NM966_05685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NM966_05695	COG0180	Tryptophanyl-tRNA synthetase
NM966_05705	COG4166	transmembrane transport
NM966_05710	COG0601	transmembrane transport
NM966_05715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NM966_05720	COG0444	Belongs to the ABC transporter superfamily
NM966_05725	COG4608	Belongs to the ABC transporter superfamily
NM966_05735	COG0456	acetyltransferase
NM966_05740	COG1393	Belongs to the ArsC family
NM966_05745	COG0861	Integral membrane protein TerC family
NM966_05750	COG4862	establishment of competence for transformation
NM966_05755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NM966_05765	COG1164	Oligoendopeptidase f
NM966_05775	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NM966_05780	COG2346	COG2346, Truncated hemoglobins
NM966_05785	COG0741	lytic transglycosylase activity
NM966_05790	COG4116	CYTH
NM966_05800	COG2357	RelA SpoT domain protein
NM966_05805	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NM966_05810	COG0564	pseudouridine synthase activity
NM966_05815	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NM966_05820	COG0475	glutathione-regulated potassium exporter activity
NM966_05820	COG0569	domain protein
NM966_05825	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NM966_05830	COG0352	thiamine-phosphate diphosphorylase activity
NM966_05840	COG2104	thiamine diphosphate biosynthetic process
NM966_05845	COG2022	thiamine diphosphate biosynthetic process
NM966_05850	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NM966_05855	COG0351	phosphomethylpyrimidine kinase
NM966_05860	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NM966_05915	COG0210	DNA helicase
NM966_05925	COG2153	protein acetylation
NM966_05930	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NM966_05935	COG2382	esterase
NM966_05940	COG0626	cystathionine gamma-synthase activity
NM966_05945	COG0626	cystathionine gamma-synthase activity
NM966_05955	COG0825	malonyl-CoA metabolic process
NM966_05970	COG0457	Tetratricopeptide repeat
NM966_05975	COG2153	protein acetylation
NM966_05980	COG2364	Membrane
NM966_05990	COG0457	Tetratricopeptide repeat
NM966_06010	COG3173	Aminoglycoside phosphotransferase
NM966_06015	COG0583	DNA-binding transcription factor activity
NM966_06035	COG0583	DNA-binding transcription factor activity
NM966_06040	COG2807	transmembrane transport
NM966_06065	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NM966_06085	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NM966_06090	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NM966_06095	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NM966_06100	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NM966_06120	COG4195	phage-related replication protein
NM966_06125	COG2856	Zn peptidase
NM966_06130	COG5632	N-Acetylmuramoyl-L-alanine amidase
NM966_06130	COG3409	Peptidoglycan-binding domain 1 protein
NM966_06145	COG0306	phosphate transporter
NM966_06150	COG1392	Phosphate transport regulator
NM966_06160	COG0405	Gamma-glutamyltransferase
NM966_06165	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NM966_06175	COG4208	sulfate ABC transporter
NM966_06190	COG3775	system Galactitol-specific IIC component
NM966_06205	COG1063	alcohol dehydrogenase
NM966_06210	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NM966_06215	COG0022	dehydrogenase e1 component
NM966_06215	COG0508	dehydrogenase complex catalyzes the overall conversion of
NM966_06220	COG0508	dehydrogenase complex catalyzes the overall conversion of
NM966_06225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NM966_06230	COG1028	Short-chain dehydrogenase reductase Sdr
NM966_06235	COG1028	Short-chain dehydrogenase reductase Sdr
NM966_06240	COG2390	Transcriptional regulator
NM966_06250	COG0531	amino acid
NM966_06255	COG0346	lactoylglutathione lyase activity
NM966_06260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NM966_06265	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NM966_06270	COG2362	D-Aminopeptidase
NM966_06275	COG0601	transmembrane transport
NM966_06280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NM966_06285	COG0444	Belongs to the ABC transporter superfamily
NM966_06290	COG4166	transmembrane transport
NM966_06295	COG1619	proteins homologs of microcin C7 resistance protein MccF
NM966_06300	COG4948	Mandelate Racemase Muconate Lactonizing
NM966_06305	COG0791	NLP P60 protein
NM966_06310	COG4608	Belongs to the ABC transporter superfamily
NM966_06315	COG1834	amidinotransferase
NM966_06320	COG1607	acyl-coa hydrolase
NM966_06325	COG1695	Transcriptional regulator
NM966_06340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NM966_06350	COG2076	Multidrug Resistance protein
NM966_06355	COG2076	Multidrug Resistance protein
NM966_06365	COG0788	formyltetrahydrofolate deformylase activity
NM966_06370	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NM966_06375	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NM966_06380	COG0457	Tetratricopeptide repeat
NM966_06390	COG1764	response to oxidative stress
NM966_06395	COG1846	Transcriptional regulator
NM966_06400	COG1764	response to oxidative stress
NM966_06405	COG0590	tRNA wobble adenosine to inosine editing
NM966_06410	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NM966_06415	COG1404	Belongs to the peptidase S8 family
NM966_06430	COG0745	RESPONSE REGULATOR receiver
NM966_06435	COG5002	protein histidine kinase activity
NM966_06435	COG3850	Histidine kinase
NM966_06440	COG3212	peptidase
NM966_06445	COG3212	peptidase
NM966_06455	COG2239	Acts as a magnesium transporter
NM966_06465	COG0583	DNA-binding transcription factor activity
NM966_06475	COG0789	Transcriptional regulator
NM966_06490	COG1846	Transcriptional regulator
NM966_06495	COG3300	MHYT domain
NM966_06495	COG5001	Diguanylate cyclase
NM966_06500	COG0586	Pfam SNARE associated Golgi protein
NM966_06505	COG0861	Integral membrane protein TerC family
NM966_06510	COG1191	sigma factor activity
NM966_06530	COG0501	Belongs to the peptidase M48B family
NM966_06535	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NM966_06540	COG2323	membrane
NM966_06555	COG3594	Acyltransferase
NM966_06560	COG5002	protein histidine kinase activity
NM966_06565	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NM966_06570	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NM966_06575	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NM966_06580	COG0436	Aminotransferase
NM966_06585	COG1850	ribulose-bisphosphate carboxylase activity
NM966_06590	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NM966_06595	COG0235	Class ii aldolase
NM966_06600	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NM966_06610	COG3852	Histidine kinase
NM966_06615	COG1846	Transcriptional regulator
NM966_06620	COG1360	Flagellar Motor Protein
NM966_06625	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NM966_06630	COG0542	response to heat
NM966_06635	COG3949	Membrane
NM966_06640	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NM966_06645	COG0720	synthase
NM966_06650	COG0602	queuosine metabolic process
NM966_06655	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NM966_06670	COG4873	Protein conserved in bacteria
NM966_06680	COG3773	Cell wall hydrolase
NM966_06685	COG2244	polysaccharide biosynthetic process
NM966_06690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NM966_06695	COG2217	Heavy metal translocating P-type atpase
NM966_06700	COG0006	proline dipeptidase activity
NM966_06705	COG1609	Transcriptional regulator
NM966_06710	COG3711	transcriptional antiterminator
NM966_06715	COG2190	(PTS) system
NM966_06715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NM966_06715	COG1263	PTS System
NM966_06720	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NM966_06725	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NM966_06735	COG1533	DNA photolyase activity
NM966_06740	COG0840	transmembrane signaling receptor activity
NM966_06750	COG2084	Dehydrogenase
NM966_06755	COG2340	Cysteine-rich secretory protein family
NM966_06760	COG0768	penicillin binding
NM966_06765	COG4191	Histidine kinase
NM966_06770	COG0436	Aminotransferase
NM966_06775	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NM966_06785	COG1714	RDD family
NM966_06795	COG0784	Response regulator, receiver
NM966_06795	COG0835	chemotaxis
NM966_06805	COG1917	Cupin 2, conserved barrel domain protein
NM966_06805	COG2207	Transcriptional regulator
NM966_06810	COG0697	spore germination
NM966_06825	COG2814	Major facilitator Superfamily
NM966_06830	COG1376	ErfK ybiS ycfS ynhG family protein
NM966_06835	COG1408	metallophosphoesterase
NM966_06840	COG1028	Short-chain dehydrogenase reductase Sdr
NM966_06845	COG2200	EAL domain
NM966_06850	COG3546	catalase activity
NM966_06855	COG4703	Protein of unknown function (DUF1797)
NM966_06860	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
NM966_06870	COG0517	IMP dehydrogenase activity
NM966_06875	COG0583	DNA-binding transcription factor activity
NM966_06885	COG0716	FMN binding
NM966_06895	COG0716	FMN binding
NM966_06900	COG2171	N-acyltransferase activity
NM966_06905	COG1473	amidohydrolase
NM966_06915	COG0668	transmembrane transport
NM966_06920	COG0450	alkyl hydroperoxide reductase
NM966_06925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NM966_06940	COG0746	molybdenum cofactor guanylyltransferase activity
NM966_06945	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NM966_06950	COG0303	'Molybdopterin
NM966_06955	COG1763	Mo-molybdopterin cofactor biosynthetic process
NM966_06960	COG0314	molybdopterin synthase activity
NM966_06965	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NM966_06980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NM966_06985	COG1136	(ABC) transporter
NM966_06990	COG0577	efflux transmembrane transporter activity
NM966_06995	COG1349	DNA-binding transcription factor activity
NM966_07000	COG1105	Belongs to the carbohydrate kinase PfkB family
NM966_07005	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NM966_07005	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NM966_07005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NM966_07010	COG0681	Belongs to the peptidase S26 family
NM966_07020	COG0488	(ABC) transporter
NM966_07025	COG2309	aminopeptidase activity
NM966_07035	COG1077	Cell shape determining protein MreB Mrl
NM966_07040	COG2002	toxin-antitoxin pair type II binding
NM966_07045	COG3852	Histidine kinase
NM966_07050	COG2105	PFAM AIG2 family protein
NM966_07050	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
NM966_07055	COG0569	domain protein
NM966_07060	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NM966_07065	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NM966_07070	COG5503	Protein of unknown function (DUF1447)
NM966_07075	COG0561	phosphatase activity
NM966_07080	COG0242	peptide deformylase activity
NM966_07095	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NM966_07100	COG0022	dehydrogenase e1 component
NM966_07105	COG0508	dehydrogenase complex catalyzes the overall conversion of
NM966_07110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NM966_07115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NM966_07125	COG1982	Orn Lys Arg decarboxylase major
NM966_07130	COG4476	Belongs to the UPF0223 family
NM966_07135	COG4493	Belongs to the UPF0637 family
NM966_07145	COG0483	inositol monophosphate 1-phosphatase activity
NM966_07160	COG1595	DNA-templated transcription, initiation
NM966_07180	COG1217	gtp-binding protein TYPA
NM966_07190	COG4896	Protein conserved in bacteria
NM966_07200	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NM966_07205	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NM966_07210	COG2066	Belongs to the glutaminase family
NM966_07215	COG4838	Belongs to the UPF0358 family
NM966_07220	COG0772	Belongs to the SEDS family
NM966_07225	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NM966_07230	COG0415	Belongs to the DNA photolyase family
NM966_07235	COG1612	heme a metabolic process
NM966_07240	COG0109	protoheme IX farnesyltransferase activity
NM966_07245	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NM966_07245	COG2010	Cytochrome c
NM966_07250	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NM966_07255	COG1845	cytochrome c oxidase, subunit III
NM966_07260	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NM966_07265	COG3336	cytochrome c oxidase
NM966_07275	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
NM966_07280	COG2340	Cysteine-rich secretory protein family
NM966_07300	COG3679	Belongs to the UPF0342 family
NM966_07305	COG4471	UPF0298 protein
NM966_07310	COG0742	ribosomal rna small subunit methyltransferase
NM966_07315	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NM966_07320	COG3314	Sporulation integral membrane protein YlbJ
NM966_07325	COG1752	Esterase of the alpha-beta hydrolase superfamily
NM966_07330	COG3480	Lon protease (S16) C-terminal proteolytic domain
NM966_07340	COG1399	metal-binding, possibly nucleic acid-binding protein
NM966_07345	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NM966_07355	COG0454	-acetyltransferase
NM966_07360	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NM966_07365	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NM966_07370	COG2001	Belongs to the MraZ family
NM966_07375	COG0275	rRNA processing
NM966_07380	COG4839	cell division protein FtsL
NM966_07385	COG0768	penicillin binding
NM966_07390	COG0768	penicillin binding
NM966_07395	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NM966_07400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NM966_07405	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NM966_07410	COG0772	Belongs to the SEDS family
NM966_07415	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NM966_07420	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NM966_07425	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NM966_07430	COG3879	Bacterial protein of unknown function (DUF881)
NM966_07435	COG3879	Bacterial protein of unknown function (DUF881)
NM966_07440	COG3856	small basic protein
NM966_07445	COG0849	cell division
NM966_07450	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NM966_07455	COG1404	Belongs to the peptidase S8 family
NM966_07455	COG4412	M6 family metalloprotease domain protein
NM966_07465	COG1191	sigma factor activity
NM966_07470	COG1191	sigma factor activity
NM966_07475	COG2390	Transcriptional regulator
NM966_07490	COG3730	PTS system glucitol sorbitol-specific
NM966_07495	COG3732	PTS system glucitol sorbitol-specific
NM966_07505	COG1119	ATPase activity
NM966_07510	COG1873	PFAM PRC-barrel domain
NM966_07515	COG1496	oxidoreductase activity
NM966_07520	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NM966_07525	COG1799	cell septum assembly
NM966_07530	COG0762	integral membrane protein
NM966_07535	COG2302	S4 RNA-binding domain
NM966_07540	COG3599	regulation of cell shape
NM966_07545	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NM966_07550	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NM966_07555	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NM966_07560	COG0564	pseudouridine synthase activity
NM966_07565	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NM966_07570	COG2233	PERMEase
NM966_07575	COG0540	Belongs to the ATCase OTCase family
NM966_07580	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NM966_07585	COG0505	Belongs to the CarA family
NM966_07590	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NM966_07595	COG0543	2 iron, 2 sulfur cluster binding
NM966_07600	COG0167	dihydroorotate dehydrogenase activity
NM966_07605	COG0284	orotidine-5'-phosphate decarboxylase activity
NM966_07610	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NM966_07620	COG0175	sulfate reduction
NM966_07625	COG0306	phosphate transporter
NM966_07630	COG2046	Belongs to the sulfate adenylyltransferase family
NM966_07635	COG0529	Catalyzes the synthesis of activated sulfate
NM966_07640	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NM966_07645	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
NM966_07650	COG1648	precorrin-2 dehydrogenase activity
NM966_07660	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NM966_07665	COG1561	YicC-like family, N-terminal region
NM966_07670	COG2052	Domain of unknown function (DUF370)
NM966_07675	COG0194	GDP metabolic process
NM966_07680	COG1758	RNA polymerase activity
NM966_07685	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NM966_07690	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NM966_07695	COG0242	peptide deformylase activity
NM966_07700	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NM966_07705	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NM966_07705	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NM966_07710	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NM966_07715	COG0631	protein serine/threonine phosphatase activity
NM966_07720	COG0515	serine threonine protein kinase
NM966_07720	COG2815	serine threonine protein kinase
NM966_07725	COG1162	GTPase activity
NM966_07730	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NM966_07735	COG1564	THIamine pyrophosphokinase
NM966_07745	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NM966_07750	COG1302	Protein conserved in bacteria
NM966_07755	COG1461	Dihydroxyacetone kinase
NM966_07760	COG1760	l-serine dehydratase
NM966_07765	COG1760	l-serine dehydratase
NM966_07770	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NM966_07775	COG1349	DNA-binding transcription factor activity
NM966_07780	COG0416	fatty acid biosynthetic process
NM966_07785	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NM966_07790	COG1028	Short-chain dehydrogenase reductase Sdr
NM966_07795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NM966_07805	COG1196	nuclear chromosome segregation
NM966_07810	COG0552	protein localization to endoplasmic reticulum
NM966_07815	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NM966_07820	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NM966_07825	COG0228	four-way junction DNA binding
NM966_07830	COG1837	Belongs to the UPF0109 family
NM966_07840	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NM966_07845	COG0336	Belongs to the RNA methyltransferase TrmD family
NM966_07850	COG0335	large ribosomal subunit rRNA binding
NM966_07855	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NM966_07860	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NM966_07870	COG2257	FlhB HrpN YscU SpaS Family
NM966_07875	COG0045	succinate-CoA ligase (ADP-forming) activity
NM966_07880	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NM966_07885	COG0758	DNA mediated transformation
NM966_07890	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NM966_07895	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NM966_07900	COG4974	Belongs to the 'phage' integrase family
NM966_07905	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NM966_07910	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NM966_07915	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NM966_07920	COG1815	bacterial-type flagellum-dependent cell motility
NM966_07925	COG1558	bacterial-type flagellum-dependent cell motility
NM966_07930	COG1677	Flagellar hook-basal body complex protein FliE
NM966_07935	COG1766	The M ring may be actively involved in energy transduction
NM966_07945	COG1317	bacterial-type flagellum organization
NM966_07950	COG1157	protein secretion by the type III secretion system
NM966_07955	COG2882	bacterial-type flagellum organization
NM966_07960	COG3334	PFAM MgtE intracellular
NM966_07965	COG3144	bacterial-type flagellum assembly
NM966_07970	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NM966_07975	COG4786	Flagellar basal body rod
NM966_07980	COG1582	Flagellar protein (FlbD)
NM966_07985	COG1580	Controls the rotational direction of flagella during chemotaxis
NM966_07990	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NM966_07995	COG1776	CheC inhibitor of MCP methylation
NM966_07995	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NM966_08000	COG2201	protein-glutamate methylesterase activity
NM966_08005	COG3190	flagellar
NM966_08010	COG1338	Plays a role in the flagellum-specific transport system
NM966_08015	COG1987	bacterial-type flagellum assembly
NM966_08020	COG1684	flagellar biosynthetic protein fliR
NM966_08025	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NM966_08030	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NM966_08035	COG1419	protein localization to endoplasmic reticulum
NM966_08040	COG0455	bacterial-type flagellum organization
NM966_08045	COG2201	protein-glutamate methylesterase activity
NM966_08050	COG0643	Histidine kinase
NM966_08050	COG2198	Histidine kinase
NM966_08055	COG0835	chemotaxis
NM966_08060	COG1776	CheC inhibitor of MCP methylation
NM966_08070	COG1191	sigma factor activity
NM966_08085	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NM966_08090	COG0528	UMP kinase activity
NM966_08095	COG0233	cytoplasmic translational termination
NM966_08100	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NM966_08105	COG4589	Belongs to the CDS family
NM966_08110	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NM966_08115	COG0750	zinc metalloprotease
NM966_08120	COG0442	prolyl-tRNA aminoacylation
NM966_08125	COG2176	DNA-directed DNA polymerase activity
NM966_08140	COG3693	PFAM glycoside hydrolase, family 10
NM966_08150	COG0779	Required for maturation of 30S ribosomal subunits
NM966_08155	COG0195	Participates in both transcription termination and antitermination
NM966_08160	COG2740	Nucleic-acid-binding protein implicated in transcription termination
NM966_08165	COG1358	cellular component organization or biogenesis
NM966_08170	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NM966_08175	COG1550	Protein conserved in bacteria
NM966_08180	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NM966_08185	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NM966_08190	COG0196	riboflavin kinase activity
NM966_08195	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NM966_08200	COG1185	polyribonucleotide nucleotidyltransferase activity
NM966_08205	COG0726	polysaccharide deacetylase
NM966_08210	COG0612	Peptidase, M16
NM966_08220	COG1873	PFAM PRC-barrel domain
NM966_08225	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NM966_08230	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NM966_08235	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NM966_08240	COG0527	aspartate kinase activity
NM966_08250	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NM966_08255	COG0740	serine-type endopeptidase activity
NM966_08265	COG4980	gas vesicle protein
NM966_08265	COG1674	ftsk spoiiie
NM966_08270	COG2188	Transcriptional regulator
NM966_08275	COG2814	Major facilitator Superfamily
NM966_08285	COG0612	Peptidase, M16
NM966_08290	COG0612	Peptidase, M16
NM966_08300	COG1033	growth of symbiont in host cell
NM966_08300	COG2409	Drug exporters of the RND superfamily
NM966_08305	COG0300	oxidoreductase activity
NM966_08320	COG1426	Protein conserved in bacteria
NM966_08325	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NM966_08330	COG1058	Belongs to the CinA family
NM966_08330	COG1546	Belongs to the CinA family
NM966_08335	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NM966_08340	COG1418	mRNA catabolic process
NM966_08345	COG1692	metallophosphoesterase
NM966_08350	COG2359	stage V sporulation protein S
NM966_08355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NM966_08360	COG1063	alcohol dehydrogenase
NM966_08365	COG0156	8-amino-7-oxononanoate synthase activity
NM966_08375	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NM966_08380	COG4550	Control of competence regulator ComK, YlbF/YmcA
NM966_08390	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NM966_08395	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NM966_08415	COG1329	Transcriptional regulator
NM966_08420	COG4195	phage-related replication protein
NM966_08425	COG0457	Tetratricopeptide repeat
NM966_08430	COG1404	Belongs to the peptidase S8 family
NM966_08435	COG4195	phage-related replication protein
NM966_08440	COG1764	response to oxidative stress
NM966_08470	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NM966_08475	COG1923	regulation of RNA biosynthetic process
NM966_08490	COG1780	Probably involved in ribonucleotide reductase function
NM966_08495	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NM966_08500	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NM966_08505	COG4112	unkown
NM966_08515	COG0464	growth
NM966_08520	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NM966_08525	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
NM966_08530	COG0789	Transcriptional regulator
NM966_08535	COG0174	glutamine synthetase
NM966_08550	COG5444	nuclease activity
NM966_08565	COG0457	Tetratricopeptide repeat
NM966_08575	COG0604	alcohol dehydrogenase
NM966_08590	COG5444	nuclease activity
NM966_08615	COG5646	InterPro IPR014922
NM966_08635	COG0457	Tetratricopeptide repeat
NM966_08645	COG3619	membrane
NM966_08650	COG1793	dna ligase
NM966_08650	COG3285	dna ligase
NM966_08655	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NM966_08660	COG4876	unkown
NM966_08670	COG1959	2 iron, 2 sulfur cluster binding
NM966_08675	COG0702	epimerase
NM966_08685	COG0247	lactate metabolic process
NM966_08695	COG1556	Lactate utilization protein
NM966_08715	COG2323	membrane
NM966_08720	COG1309	transcriptional regulator
NM966_08725	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NM966_08725	COG2124	cytochrome p450
NM966_08730	COG3591	Belongs to the peptidase S1B family
NM966_08735	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NM966_08740	COG3209	COG3209 Rhs family protein
NM966_08745	COG1366	Belongs to the anti-sigma-factor antagonist family
NM966_08760	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NM966_08765	COG1388	LysM domain
NM966_08770	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NM966_08775	COG4224	UPF0291 protein
NM966_08780	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NM966_08790	COG3763	UPF0154 protein
NM966_08800	COG0785	Cytochrome C biogenesis protein
NM966_08805	COG4846	Membrane protein involved in cytochrome C biogenesis
NM966_08815	COG0071	Belongs to the small heat shock protein (HSP20) family
NM966_08830	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NM966_08835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NM966_08855	COG0824	Thioesterase
NM966_08865	COG4841	protein insertion into membrane
NM966_08870	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NM966_08875	COG1832	CoA-binding protein
NM966_08880	COG0187	DNA topoisomerase II activity
NM966_08885	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NM966_08895	COG0738	Major facilitator superfamily
NM966_08900	COG0473	3-isopropylmalate dehydrogenase activity
NM966_08910	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NM966_08915	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NM966_08920	COG0640	Transcriptional regulator
NM966_08930	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NM966_08935	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NM966_08945	COG1309	transcriptional regulator
NM966_08950	COG2249	NAD(P)H dehydrogenase (quinone) activity
NM966_08955	COG1733	regulation of RNA biosynthetic process
NM966_08965	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NM966_08970	COG0251	oxidation-reduction process
NM966_09010	COG0657	acetylesterase activity
NM966_09020	COG2723	6-phospho-beta-galactosidase activity
NM966_09025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NM966_09025	COG1263	PTS System
NM966_09025	COG2190	(PTS) system
NM966_09040	COG2205	protein histidine kinase activity
NM966_09045	COG0745	RESPONSE REGULATOR receiver
NM966_09055	COG3507	Belongs to the glycosyl hydrolase 43 family
NM966_09060	COG1012	belongs to the aldehyde dehydrogenase family
NM966_09065	COG1486	melibiose metabolic process
NM966_09070	COG0395	ABC-type sugar transport system, permease component
NM966_09075	COG1175	transmembrane transport
NM966_09080	COG1653	transport
NM966_09085	COG1609	Transcriptional regulator
NM966_09090	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NM966_09105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NM966_09115	COG0456	acetyltransferase
NM966_09120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NM966_09135	COG1846	Transcriptional regulator
NM966_09140	COG2814	Major facilitator Superfamily
NM966_09150	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NM966_09150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NM966_09150	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NM966_09155	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NM966_09155	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NM966_09155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NM966_09170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NM966_09190	COG1012	belongs to the aldehyde dehydrogenase family
NM966_09195	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NM966_09200	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NM966_09205	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NM966_09210	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NM966_09215	COG1024	Enoyl-CoA hydratase
NM966_09220	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NM966_09225	COG0511	ligase activity, forming carbon-carbon bonds
NM966_09230	COG0439	Biotin carboxylase
NM966_09235	COG0318	PFAM AMP-dependent synthetase and ligase
NM966_09240	COG1960	acyl-CoA dehydrogenase activity
NM966_09250	COG2365	Tyrosine phosphatase family
NM966_09255	COG1349	DNA-binding transcription factor activity
NM966_09260	COG1942	4-Oxalocrotonate Tautomerase
NM966_09270	COG3835	regulator
NM966_09275	COG0277	FAD linked oxidase domain protein
NM966_09280	COG0247	lactate metabolic process
NM966_09300	COG0166	Belongs to the GPI family
NM966_09305	COG2246	polysaccharide biosynthetic process
NM966_09310	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NM966_09315	COG0586	Pfam SNARE associated Golgi protein
NM966_09320	COG1587	Uroporphyrinogen-III synthase
NM966_09330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NM966_09345	COG0534	Mate efflux family protein
NM966_09350	COG2027	D-alanyl-D-alanine carboxypeptidase
NM966_09355	COG4677	pectinesterase activity
NM966_09360	COG2323	membrane
NM966_09365	COG2146	nitrite reductase [NAD(P)H] activity
NM966_09370	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NM966_09375	COG0243	molybdopterin cofactor binding
NM966_09380	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NM966_09385	COG2223	nitrite transmembrane transporter activity
NM966_09390	COG0493	'glutamate synthase
NM966_09395	COG0067	glutamate synthase
NM966_09395	COG0069	glutamate synthase activity
NM966_09395	COG0070	glutamate synthase
NM966_09400	COG0583	DNA-binding transcription factor activity
NM966_09410	COG1132	(ABC) transporter
NM966_09415	COG0789	Transcriptional regulator
NM966_09415	COG4978	Transcriptional regulator
NM966_09420	COG0454	-acetyltransferase
NM966_09425	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NM966_09430	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NM966_09435	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NM966_09445	COG0243	molybdopterin cofactor binding
NM966_09455	COG1070	Carbohydrate kinase
NM966_09460	COG2115	Belongs to the xylose isomerase family
NM966_09465	COG1940	carbohydrate kinase activity
NM966_09475	COG2211	Major facilitator Superfamily
NM966_09480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NM966_09485	COG1994	Peptidase M50
NM966_09505	COG1309	transcriptional regulator
NM966_09510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NM966_09515	COG3708	Transcriptional regulator
NM966_09520	COG2378	regulation of single-species biofilm formation
NM966_09530	COG0640	Transcriptional regulator
NM966_09535	COG0531	amino acid
NM966_09540	COG0741	lytic transglycosylase activity
NM966_09545	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NM966_09550	COG2079	MmgE PrpD family protein
NM966_09555	COG0372	Belongs to the citrate synthase family
NM966_09560	COG2322	membrane
NM966_09570	COG3584	3D domain protein
NM966_09570	COG1388	LysM domain
NM966_09575	COG0514	ATP-dependent DNA helicase (RecQ)
NM966_09585	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NM966_09610	COG1012	belongs to the aldehyde dehydrogenase family
NM966_09615	COG1657	PFAM Prenyltransferase squalene oxidase
NM966_09620	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NM966_09625	COG0385	Bile acid
NM966_09630	COG0508	dehydrogenase complex catalyzes the overall conversion of
NM966_09635	COG0567	Dehydrogenase, E1 component
NM966_09640	COG4548	von Willebrand factor, type A
NM966_09645	COG0714	Associated with various cellular activities
NM966_09650	COG2032	superoxide dismutase activity
NM966_09655	COG0791	NLP P60 protein
NM966_09655	COG1388	LysM domain
NM966_09660	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NM966_09665	COG0534	Mate efflux family protein
NM966_09675	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NM966_09680	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NM966_09690	COG2962	Rard protein
NM966_09705	COG1733	regulation of RNA biosynthetic process
NM966_09710	COG0778	Nitroreductase
NM966_09720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NM966_09725	COG0793	Belongs to the peptidase S41A family
NM966_09725	COG3409	Peptidoglycan-binding domain 1 protein
NM966_09730	COG2226	methyltransferase
NM966_09740	COG1876	peptidase activity
NM966_09745	COG0813	purine-nucleoside phosphorylase activity
NM966_09755	COG0671	phosphoesterase, PA-phosphatase related
NM966_09770	COG4479	Belongs to the UPF0346 family
NM966_09780	COG1509	lysine 2,3-aminomutase activity
NM966_09785	COG3829	transcription factor binding
NM966_09790	COG0463	Glycosyl transferase, family 2
NM966_09805	COG4641	Protein conserved in bacteria
NM966_09815	COG1086	Polysaccharide biosynthesis protein
NM966_09820	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NM966_09825	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NM966_09830	COG1846	Transcriptional regulator
NM966_09850	COG4698	Protein conserved in bacteria
NM966_09855	COG2755	lipolytic protein G-D-S-L family
NM966_09860	COG1999	signal sequence binding
NM966_09875	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NM966_09880	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NM966_09885	COG1272	protein, Hemolysin III
NM966_09890	COG0204	Acyl-transferase
NM966_09895	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NM966_09900	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NM966_09905	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NM966_09915	COG2136	Putative SAM-dependent methyltransferase
NM966_09915	COG2521	methyltransferase
NM966_09925	COG0129	dihydroxy-acid dehydratase activity
NM966_09930	COG1413	lyase activity
NM966_09935	COG1418	mRNA catabolic process
NM966_09940	COG0386	Belongs to the glutathione peroxidase family
NM966_09945	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NM966_09950	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NM966_09955	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NM966_09965	COG1278	Cold shock
NM966_09980	COG0328	RNA-DNA hybrid ribonuclease activity
NM966_09985	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NM966_09990	COG0328	RNA-DNA hybrid ribonuclease activity
NM966_10000	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NM966_10010	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NM966_10015	COG1755	Isoprenylcysteine carboxyl methyltransferase
NM966_10020	COG3424	synthase
NM966_10025	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NM966_10030	COG0726	polysaccharide deacetylase
NM966_10035	COG2233	PERMEase
NM966_10040	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NM966_10045	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NM966_10050	COG1199	ATP-dependent helicase activity
NM966_10060	COG0116	Belongs to the methyltransferase superfamily
NM966_10070	COG3599	regulation of cell shape
NM966_10075	COG4474	Belongs to the UPF0398 family
NM966_10085	COG3359	exonuclease
NM966_10090	COG1111	helicase
NM966_10090	COG1205	dead DEAH box helicase
NM966_10095	COG1902	pentaerythritol trinitrate reductase activity
NM966_10100	COG2190	(PTS) system
NM966_10105	COG0071	Belongs to the small heat shock protein (HSP20) family
NM966_10135	COG3331	DNA recombination
NM966_10140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NM966_10140	COG4499	WXG100 protein secretion system (Wss), protein YukC
NM966_10150	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NM966_10155	COG3935	DnaD domain protein
NM966_10160	COG0017	Asparaginyl-tRNA synthetase
NM966_10165	COG5353	protein conserved in bacteria
NM966_10175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NM966_10175	COG1199	ATP-dependent helicase activity
NM966_10180	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NM966_10185	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NM966_10190	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NM966_10200	COG0617	tRNA 3'-terminal CCA addition
NM966_10205	COG0438	transferase activity, transferring glycosyl groups
NM966_10210	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NM966_10215	COG1803	Methylglyoxal synthase
NM966_10220	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NM966_10225	COG1694	Mazg nucleotide pyrophosphohydrolase
NM966_10230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NM966_10240	COG4347	Protein of unknown function (DUF1405)
NM966_10245	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NM966_10245	COG2010	Cytochrome c
NM966_10250	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NM966_10255	COG0723	plastoquinol--plastocyanin reductase activity
NM966_10265	COG5582	Belongs to the UPF0302 family
NM966_10270	COG0457	Tetratricopeptide repeat
NM966_10275	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NM966_10280	COG0287	Prephenate dehydrogenase
NM966_10285	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NM966_10290	COG0159	tryptophan synthase activity
NM966_10295	COG0133	tryptophan synthase activity
NM966_10300	COG0135	phosphoribosylanthranilate isomerase activity
NM966_10305	COG0134	indole-3-glycerol-phosphate synthase activity
NM966_10310	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NM966_10320	COG4401	Chorismate mutase type I
NM966_10325	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NM966_10330	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NM966_10335	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NM966_10340	COG0105	UTP biosynthetic process
NM966_10345	COG0142	geranyltranstransferase activity
NM966_10350	COG2226	methyltransferase
NM966_10355	COG0142	geranyltranstransferase activity
NM966_10365	COG0302	gtp cyclohydrolase
NM966_10370	COG0776	regulation of translation
NM966_10375	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NM966_10390	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NM966_10395	COG1160	GTP binding
NM966_10420	COG1304	FMN binding
NM966_10425	COG0539	negative regulation of cytoplasmic translation
NM966_10430	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NM966_10440	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
NM966_10445	COG2959	enzyme of heme biosynthesis
NM966_10450	COG3773	Cell wall hydrolase
NM966_10450	COG3409	Peptidoglycan-binding domain 1 protein
NM966_10455	COG2339	peptidase activity
NM966_10460	COG0492	ferredoxin-NADP+ reductase activity
NM966_10465	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NM966_10470	COG4862	establishment of competence for transformation
NM966_10475	COG1408	metallophosphoesterase
NM966_10485	COG1388	LysM domain
NM966_10490	COG1266	CAAX protease self-immunity
NM966_10495	COG0514	ATP-dependent DNA helicase (RecQ)
NM966_10500	COG4955	Helix-turn-helix domain
NM966_10505	COG1141	Ferredoxin
NM966_10510	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NM966_10515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NM966_10530	COG1595	DNA-templated transcription, initiation
NM966_10535	COG5002	protein histidine kinase activity
NM966_10540	COG0745	RESPONSE REGULATOR receiver
NM966_10545	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NM966_10550	COG1333	cytochrome c biogenesis protein
NM966_10555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NM966_10560	COG1187	pseudouridine synthase activity
NM966_10565	COG0700	Nucleoside recognition
NM966_10570	COG2715	membrane protein required for spore maturation
NM966_10575	COG1686	Belongs to the peptidase S11 family
NM966_10585	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NM966_10590	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NM966_10600	COG1547	Domain of unknown function (DUF309)
NM966_10605	COG0456	acetyltransferase
NM966_10610	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NM966_10620	COG0307	riboflavin synthase, alpha
NM966_10640	COG2814	Major facilitator Superfamily
NM966_10645	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NM966_10650	COG4086	secreted protein
NM966_10655	COG0019	diaminopimelate decarboxylase activity
NM966_10660	COG0697	spore germination
NM966_10675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NM966_10695	COG1191	sigma factor activity
NM966_10700	COG2172	sigma factor antagonist activity
NM966_10710	COG1686	Belongs to the peptidase S11 family
NM966_10715	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NM966_10720	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NM966_10725	COG4974	Belongs to the 'phage' integrase family
NM966_10735	COG0735	belongs to the Fur family
NM966_10740	COG1300	Membrane
NM966_10745	COG1404	Belongs to the peptidase S8 family
NM966_10755	COG2153	protein acetylation
NM966_10760	COG1379	DNA repair
NM966_10765	COG0494	nUDIX hydrolase
NM966_10770	COG0667	Aldo Keto reductase
NM966_10780	COG1073	alpha beta
NM966_10785	COG0457	Tetratricopeptide repeat
NM966_10795	COG4918	Iron-sulphur cluster biosynthesis
NM966_10800	COG4305	rare lipoprotein A
NM966_10805	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NM966_10805	COG0456	acetyltransferase
NM966_10810	COG0456	acetyltransferase
NM966_10820	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NM966_10830	COG2211	Major facilitator Superfamily
NM966_10835	COG1072	(Pantothenic acid kinase))
NM966_10840	COG0446	pyridine nucleotide-disulphide oxidoreductase
NM966_10850	COG0300	oxidoreductase activity
NM966_10855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NM966_10860	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NM966_10870	COG4187	Peptidase family M20/M25/M40
NM966_10875	COG1902	pentaerythritol trinitrate reductase activity
NM966_10880	COG0596	Alpha beta hydrolase
NM966_10885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NM966_10895	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NM966_10900	COG2188	Transcriptional regulator
NM966_10905	COG2723	6-phospho-beta-galactosidase activity
NM966_10910	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NM966_10915	COG1447	Phosphotransferase system cellobiose-specific component IIA
NM966_10920	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NM966_10930	COG1028	Short-chain dehydrogenase reductase Sdr
NM966_10940	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NM966_10945	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NM966_10955	COG0706	membrane insertase activity
NM966_10960	COG0835	chemotaxis
NM966_10965	COG2195	Cleaves the N-terminal amino acid of tripeptides
NM966_10970	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NM966_10975	COG0346	lactoylglutathione lyase activity
NM966_10985	COG1376	ErfK ybiS ycfS ynhG family protein
NM966_10990	COG4129	membrane
NM966_10995	COG1126	abc transporter atp-binding protein
NM966_11000	COG0765	amino acid transport
NM966_11005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NM966_11015	COG1597	lipid kinase activity
NM966_11025	COG0508	dehydrogenase complex catalyzes the overall conversion of
NM966_11030	COG0022	dehydrogenase e1 component
NM966_11035	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NM966_11040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NM966_11045	COG3426	butyrate kinase activity
NM966_11055	COG0280	phosphate acetyltransferase
NM966_11060	COG3290	protein histidine kinase activity
NM966_11060	COG3829	transcription factor binding
NM966_11070	COG0584	glycerophosphoryl diester phosphodiesterase
NM966_11075	COG0457	Tetratricopeptide repeat
NM966_11080	COG0745	RESPONSE REGULATOR receiver
NM966_11085	COG0750	zinc metalloprotease
NM966_11090	COG0497	DNA recombination
NM966_11095	COG1438	arginine binding
NM966_11100	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
NM966_11105	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NM966_11110	COG0142	geranyltranstransferase activity
NM966_11115	COG1722	exodeoxyribonuclease VII activity
NM966_11120	COG1570	exodeoxyribonuclease VII activity
NM966_11125	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NM966_11130	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NM966_11135	COG1302	Protein conserved in bacteria
NM966_11140	COG0439	Biotin carboxylase
NM966_11145	COG0511	ligase activity, forming carbon-carbon bonds
NM966_11185	COG3854	ATPases associated with a variety of cellular activities
NM966_11195	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NM966_11200	COG0006	proline dipeptidase activity
NM966_11205	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NM966_11215	COG3872	metal-dependent enzyme
NM966_11225	COG1752	Esterase of the alpha-beta hydrolase superfamily
NM966_11230	COG1321	iron dependent repressor
NM966_11235	COG0095	Lipoate-protein ligase
NM966_11240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NM966_11245	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NM966_11250	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NM966_11255	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NM966_11260	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NM966_11285	COG0681	Belongs to the peptidase S26 family
NM966_11320	COG4970	Tfp pilus assembly protein FimT
NM966_11325	COG4537	Required for transformation and DNA binding
NM966_11330	COG1459	type II secretion system
NM966_11335	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NM966_11340	COG1366	Belongs to the anti-sigma-factor antagonist family
NM966_11350	COG1393	Belongs to the ArsC family
NM966_11360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NM966_11370	COG0011	TIGRFAM Protein of
NM966_11375	COG2814	Major facilitator Superfamily
NM966_11380	COG2866	Carboxypeptidase
NM966_11385	COG1368	sulfuric ester hydrolase activity
NM966_11390	COG1940	carbohydrate kinase activity
NM966_11395	COG4483	Protein conserved in bacteria
NM966_11400	COG0705	Rhomboid family
NM966_11400	COG0457	Tetratricopeptide repeat
NM966_11415	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NM966_11420	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NM966_11430	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NM966_11435	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NM966_11440	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NM966_11445	COG0581	inorganic phosphate transmembrane transporter activity
NM966_11450	COG0573	inorganic phosphate transmembrane transporter activity
NM966_11455	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NM966_11460	COG0768	penicillin binding
NM966_11465	COG0477	Major facilitator Superfamily
NM966_11470	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NM966_11475	COG2839	Protein conserved in bacteria
NM966_11480	COG5521	maltodextrose utilization protein MalA
NM966_11485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NM966_11490	COG1388	LysM domain
NM966_11495	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NM966_11500	COG4709	membrane
NM966_11505	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
NM966_11510	COG1940	carbohydrate kinase activity
NM966_11515	COG0735	belongs to the Fur family
NM966_11520	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NM966_11525	COG1121	(ABC) transporter
NM966_11530	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NM966_11545	COG0513	Belongs to the DEAD box helicase family
NM966_11555	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NM966_11560	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NM966_11565	COG2384	SAM-dependent methyltransferase
NM966_11570	COG2010	Cytochrome c
NM966_11575	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NM966_11580	COG0358	DNA primase activity
NM966_11585	COG1671	Belongs to the UPF0178 family
NM966_11590	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NM966_11595	COG0517	IMP dehydrogenase activity
NM966_11600	COG0751	glycine-tRNA ligase activity
NM966_11605	COG0752	glycyl-tRNA synthetase alpha subunit
NM966_11610	COG1381	Involved in DNA repair and RecF pathway recombination
NM966_11620	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NM966_11625	COG0295	cytidine deaminase activity
NM966_11630	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NM966_11635	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NM966_11640	COG1480	7TM receptor with intracellular HD hydrolase
NM966_11645	COG1702	phosphate starvation-inducible protein PhoH
NM966_11650	COG0561	phosphatase activity
NM966_11665	COG4864	UPF0365 protein
NM966_11670	COG1030	water channel activity
NM966_11675	COG1610	YqeY-like protein
NM966_11685	COG1283	sodium-dependent phosphate transmembrane transporter activity
NM966_11690	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NM966_11695	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NM966_11700	COG2264	protein methyltransferase activity
NM966_11705	COG0484	heat shock protein binding
NM966_11710	COG0443	Heat shock 70 kDa protein
NM966_11715	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NM966_11720	COG1420	regulation of RNA biosynthetic process
NM966_11725	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NM966_11730	COG0481	GTPase activity
NM966_11740	COG0860	N-Acetylmuramoyl-L-alanine amidase
NM966_11745	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NM966_11750	COG0268	Binds directly to 16S ribosomal RNA
NM966_11755	COG1466	dna polymerase III delta subunit
NM966_11765	COG0658	competence protein
NM966_11765	COG2333	competence protein COMEC
NM966_11770	COG2131	deaminase
NM966_11775	COG1555	photosystem II stabilization
NM966_11775	COG1596	polysaccharide export
NM966_11780	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NM966_11785	COG2226	methyltransferase
NM966_11790	COG0799	negative regulation of ribosome biogenesis
NM966_11795	COG1713	HD superfamily hydrolase involved in NAD metabolism
NM966_11800	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NM966_11805	COG1534	Rna-binding protein
NM966_11810	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NM966_11815	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NM966_11820	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
NM966_11835	COG2755	lipolytic protein G-D-S-L family
NM966_11845	COG0457	Tetratricopeptide repeat
NM966_11865	COG2186	Transcriptional regulator
NM966_11880	COG1028	Short-chain dehydrogenase reductase Sdr
NM966_11885	COG3958	Transketolase
NM966_11890	COG3959	Transketolase, thiamine diphosphate binding domain
NM966_11910	COG0726	polysaccharide deacetylase
NM966_11945	COG1131	(ABC) transporter
NM966_11970	COG2160	L-arabinose isomerase activity
NM966_11985	COG1609	Transcriptional regulator
NM966_11995	COG1846	Transcriptional regulator
NM966_12005	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NM966_12010	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
NM966_12015	COG1733	regulation of RNA biosynthetic process
NM966_12020	COG0657	acetylesterase activity
NM966_12085	COG2602	Beta-lactamase
NM966_12090	COG1960	acyl-CoA dehydrogenase activity
NM966_12095	COG1126	abc transporter atp-binding protein
NM966_12100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NM966_12105	COG0765	amino acid transport
NM966_12115	COG3546	catalase activity
NM966_12120	COG1063	alcohol dehydrogenase
NM966_12130	COG1028	Short-chain dehydrogenase reductase Sdr
NM966_12140	COG1115	amino acid carrier protein
NM966_12145	COG0583	DNA-binding transcription factor activity
NM966_12150	COG0842	Transport permease protein
NM966_12155	COG1511	domain protein
NM966_12155	COG0842	Transport permease protein
NM966_12160	COG1131	(ABC) transporter
NM966_12165	COG1063	alcohol dehydrogenase
NM966_12170	COG2226	methyltransferase
NM966_12195	COG0626	cystathionine gamma-synthase activity
NM966_12200	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NM966_12205	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NM966_12210	COG2226	methyltransferase
NM966_12225	COG0768	penicillin binding
NM966_12230	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NM966_12235	COG0572	uridine kinase
NM966_12240	COG0826	peptidase U32
NM966_12245	COG0826	peptidase U32
NM966_12250	COG4122	O-methyltransferase activity
NM966_12255	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NM966_12260	COG0183	Belongs to the thiolase family
NM966_12265	COG0318	PFAM AMP-dependent synthetase and ligase
NM966_12270	COG1268	BioY protein
NM966_12275	COG3906	Belongs to the UPF0473 family
NM966_12280	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NM966_12285	COG4472	Bacterial protein of unknown function (DUF965)
NM966_12290	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NM966_12295	COG0628	permease
NM966_12300	COG1126	abc transporter atp-binding protein
NM966_12305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NM966_12310	COG0765	amino acid transport
NM966_12315	COG0765	amino acid transport
NM966_12330	COG3881	PFAM PRC-barrel domain
NM966_12335	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NM966_12340	COG0457	Tetratricopeptide repeat
NM966_12345	COG0482	sulfurtransferase activity
NM966_12350	COG1104	cysteine desulfurase activity
NM966_12355	COG1959	2 iron, 2 sulfur cluster binding
NM966_12360	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NM966_12365	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NM966_12380	COG0124	histidyl-tRNA synthetase
NM966_12390	COG0860	N-Acetylmuramoyl-L-alanine amidase
NM966_12390	COG3103	Sh3 type 3 domain protein
NM966_12390	COG4991	sh3 domain protein
NM966_12395	COG1490	D-aminoacyl-tRNA deacylase activity
NM966_12400	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NM966_12405	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NM966_12410	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NM966_12410	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NM966_12415	COG5416	Lipopolysaccharide assembly protein A domain
NM966_12420	COG0490	domain, Protein
NM966_12425	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NM966_12425	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NM966_12435	COG2244	polysaccharide biosynthetic process
NM966_12440	COG2323	membrane
NM966_12450	COG1862	Preprotein translocase
NM966_12455	COG0343	queuine tRNA-ribosyltransferase activity
NM966_12460	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NM966_12470	COG2255	four-way junction helicase activity
NM966_12475	COG0632	four-way junction helicase activity
NM966_12485	COG2112	serine threonine protein kinase
NM966_12500	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NM966_12515	COG1388	LysM domain
NM966_12520	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NM966_12525	COG0157	Belongs to the NadC ModD family
NM966_12530	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NM966_12535	COG1104	cysteine desulfurase activity
NM966_12540	COG1827	regulation of RNA biosynthetic process
NM966_12545	COG0077	Prephenate dehydratase
NM966_12550	COG4492	Belongs to the UPF0735 family
NM966_12555	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NM966_12560	COG3290	protein histidine kinase activity
NM966_12565	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NM966_12570	COG2868	ribosomal protein
NM966_12575	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NM966_12580	COG1994	Peptidase M50
NM966_12585	COG0739	heme binding
NM966_12590	COG2894	cell division
NM966_12595	COG0850	regulation of cytokinetic process
NM966_12600	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NM966_12610	COG1077	Cell shape determining protein MreB Mrl
NM966_12615	COG2003	Belongs to the UPF0758 family
NM966_12620	COG0424	maF-like protein
NM966_12635	COG0285	dihydrofolate synthase activity
NM966_12640	COG0525	valine-tRNA ligase activity
NM966_12650	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NM966_12655	COG1388	LysM domain
NM966_12660	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NM966_12665	COG0113	porphobilinogen synthase activity
NM966_12670	COG1587	Uroporphyrinogen-III synthase
NM966_12675	COG0181	hydroxymethylbilane synthase activity
NM966_12680	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NM966_12685	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NM966_12695	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NM966_12700	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NM966_12705	COG0470	DNA polymerase III
NM966_12705	COG1067	ATP-dependent peptidase activity
NM966_12710	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NM966_12715	COG0544	peptidyl-prolyl cis-trans isomerase activity
NM966_12720	COG0457	Tetratricopeptide repeat
NM966_12720	COG1477	protein flavinylation
NM966_12725	COG0066	3-isopropylmalate dehydratase activity
NM966_12730	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NM966_12735	COG0473	3-isopropylmalate dehydrogenase activity
NM966_12740	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NM966_12745	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NM966_12750	COG0440	acetolactate synthase activity
NM966_12755	COG0028	Belongs to the TPP enzyme family
NM966_12760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NM966_12765	COG2706	6-phosphogluconolactonase activity
NM966_12770	COG3339	Conserved Protein
NM966_12775	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NM966_12780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NM966_12785	COG1696	Membrane protein involved in D-alanine export
NM966_12790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM966_12845	COG0582	viral genome integration into host DNA
NM966_12940	COG0622	Phosphoesterase
NM966_12945	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NM966_12950	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NM966_12955	COG5401	PFAM Sporulation and spore germination
NM966_12960	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NM966_12965	COG1846	Transcriptional regulator
NM966_12970	COG2197	response regulator
NM966_12975	COG2851	Citrate transporter
NM966_12980	COG0583	DNA-binding transcription factor activity
NM966_12985	COG2828	Protein conserved in bacteria
NM966_12995	COG0824	Thioesterase
NM966_13000	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NM966_13005	COG1053	succinate dehydrogenase
NM966_13010	COG2009	succinate dehydrogenase
NM966_13015	COG1719	4-vinyl reductase, 4VR
NM966_13020	COG0527	aspartate kinase activity
NM966_13025	COG0322	excinuclease ABC activity
NM966_13030	COG3118	belongs to the thioredoxin family
NM966_13035	COG3534	alpha-L-arabinofuranosidase
NM966_13040	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NM966_13045	COG2086	electron transfer activity
NM966_13050	COG1024	Enoyl-CoA hydratase
NM966_13055	COG1309	transcriptional regulator
NM966_13060	COG0318	PFAM AMP-dependent synthetase and ligase
NM966_13070	COG3766	membrane
NM966_13075	COG1193	negative regulation of DNA recombination
NM966_13080	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NM966_13080	COG1796	DNA polymerase
NM966_13085	COG1286	toxin biosynthetic process
NM966_13090	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NM966_13095	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NM966_13100	COG0072	phenylalanine-tRNA ligase activity
NM966_13100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NM966_13105	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NM966_13110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NM966_13120	COG1966	Carbon starvation protein
NM966_13125	COG1363	Peptidase, m42
NM966_13135	COG3326	Membrane
NM966_13140	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NM966_13145	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NM966_13150	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NM966_13160	COG1011	Hydrolase
NM966_13170	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NM966_13180	COG0398	Pfam SNARE associated Golgi protein
NM966_13185	COG1484	DNA-dependent DNA replication
NM966_13190	COG3611	Membrane attachment protein
NM966_13195	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NM966_13205	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NM966_13210	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NM966_13215	COG0237	dephospho-CoA kinase activity
NM966_13220	COG1971	Probably functions as a manganese efflux pump
NM966_13225	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NM966_13230	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NM966_13230	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NM966_13235	COG5002	protein histidine kinase activity
NM966_13240	COG0745	RESPONSE REGULATOR receiver
NM966_13245	COG0039	L-malate dehydrogenase activity
NM966_13250	COG0538	isocitrate dehydrogenase activity
NM966_13255	COG0372	Belongs to the citrate synthase family
NM966_13260	COG2707	UPF0756 membrane protein
NM966_13265	COG0628	permease
NM966_13270	COG3030	protein affecting phage T7 exclusion by the F plasmid
NM966_13280	COG0205	6-phosphofructokinase activity
NM966_13285	COG0825	malonyl-CoA metabolic process
NM966_13290	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NM966_13295	COG0281	malic enzyme
NM966_13300	COG0587	DNA-directed DNA polymerase activity
NM966_13320	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NM966_13330	COG4109	DRTGG domain
NM966_13335	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NM966_13340	COG1028	Short-chain dehydrogenase reductase Sdr
NM966_13350	COG0165	Argininosuccinate lyase
NM966_13355	COG0137	argininosuccinate synthase activity
NM966_13360	COG0521	Mo-molybdopterin cofactor biosynthetic process
NM966_13370	COG0827	DNA restriction-modification system
NM966_13375	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NM966_13380	COG3874	Sporulation protein YtfJ
NM966_13390	COG1714	RDD family
NM966_13395	COG0616	signal peptide processing
NM966_13400	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NM966_13410	COG3239	Fatty acid desaturase
NM966_13415	COG4585	Histidine kinase
NM966_13420	COG2197	response regulator
NM966_13425	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NM966_13430	COG0745	RESPONSE REGULATOR receiver
NM966_13435	COG2205	protein histidine kinase activity
NM966_13440	COG0772	Belongs to the SEDS family
NM966_13445	COG1695	Transcriptional regulator
NM966_13450	COG1136	(ABC) transporter
NM966_13455	COG0577	efflux transmembrane transporter activity
NM966_13460	COG0402	S-adenosylhomocysteine deaminase activity
NM966_13465	COG2249	NAD(P)H dehydrogenase (quinone) activity
NM966_13475	COG1279	arginine transmembrane transporter activity
NM966_13480	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NM966_13490	COG0301	tRNA thio-modification
NM966_13495	COG1104	cysteine desulfurase activity
NM966_13500	COG1114	Component of the transport system for branched-chain amino acids
NM966_13505	COG1114	Component of the transport system for branched-chain amino acids
NM966_13510	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NM966_13515	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NM966_13520	COG1309	transcriptional regulator
NM966_13525	COG1956	GAF domain-containing protein
NM966_13530	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NM966_13540	COG1335	isochorismatase
NM966_13550	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NM966_13555	COG2329	Antibiotic biosynthesis monooxygenase
NM966_13560	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NM966_13565	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NM966_13570	COG0454	-acetyltransferase
NM966_13575	COG0517	IMP dehydrogenase activity
NM966_13580	COG0123	including yeast histone deacetylase and acetoin utilization protein
NM966_13585	COG1609	Transcriptional regulator
NM966_13590	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NM966_13590	COG1605	Chorismate mutase
NM966_13595	COG3118	belongs to the thioredoxin family
NM966_13600	COG4980	gas vesicle protein
NM966_13605	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NM966_13610	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NM966_13615	COG1674	ftsk spoiiie
NM966_13620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NM966_13625	COG4848	Belongs to the UPF0354 family
NM966_13630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NM966_13645	COG1363	Peptidase, m42
NM966_13650	COG5584	Small secreted protein
NM966_13655	COG0281	malic enzyme
NM966_13660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NM966_13665	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NM966_13675	COG0510	thiamine kinase activity
NM966_13680	COG1597	lipid kinase activity
NM966_13690	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NM966_13695	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NM966_13700	COG3340	Belongs to the peptidase S51 family
NM966_13705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NM966_13710	COG2252	PERMEase
NM966_13715	COG1349	DNA-binding transcription factor activity
NM966_13720	COG1187	pseudouridine synthase activity
NM966_13725	COG2244	polysaccharide biosynthetic process
NM966_13730	COG2081	HI0933 family
NM966_13740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NM966_13745	COG3196	Protein conserved in bacteria
NM966_13755	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NM966_13760	COG5578	integral membrane protein
NM966_13765	COG0673	inositol 2-dehydrogenase activity
NM966_13770	COG1653	transport
NM966_13775	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NM966_13780	COG4209	transmembrane transport
NM966_13785	COG2207	Transcriptional regulator
NM966_13790	COG1733	regulation of RNA biosynthetic process
NM966_13795	COG2814	Major facilitator Superfamily
NM966_13800	COG0656	L-ascorbic acid biosynthetic process
NM966_13805	COG1653	transport
NM966_13810	COG0395	ABC-type sugar transport system, permease component
NM966_13815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NM966_13820	COG1073	alpha beta
NM966_13825	COG0495	leucyl-tRNA aminoacylation
NM966_13835	COG2202	Pas domain
NM966_13835	COG1366	Belongs to the anti-sigma-factor antagonist family
NM966_13840	COG2433	Pfam Transposase IS66
NM966_13845	COG0577	efflux transmembrane transporter activity
NM966_13850	COG1136	(ABC) transporter
NM966_13860	COG1131	(ABC) transporter
NM966_13865	COG1725	Transcriptional regulator
NM966_13885	COG1242	4 iron, 4 sulfur cluster binding
NM966_13890	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NM966_13895	COG4326	sporulation control protein
NM966_13905	COG2267	carboxylic ester hydrolase activity
NM966_13910	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NM966_13915	COG0367	asparagine synthase
NM966_13920	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NM966_13925	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NM966_13935	COG1506	peptidase
NM966_13940	COG1233	COG1233 Phytoene dehydrogenase and related
NM966_13960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NM966_13965	COG1116	anion transmembrane transporter activity
NM966_13970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NM966_13975	COG0494	nUDIX hydrolase
NM966_13980	COG2310	stress, protein
NM966_13995	COG4824	toxin secretion phage lysis holin
NM966_14005	COG0783	Belongs to the Dps family
NM966_14020	COG1854	S-ribosylhomocysteine lyase activity
NM966_14025	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NM966_14030	COG0288	reversible hydration of carbon dioxide
NM966_14035	COG0803	Belongs to the bacterial solute-binding protein 9 family
NM966_14035	COG3443	Belongs to the bacterial solute-binding protein 9 family
NM966_14045	COG1271	oxidase subunit
NM966_14050	COG1294	oxidase, subunit
NM966_14065	COG4948	Mandelate Racemase Muconate Lactonizing
NM966_14070	COG0318	PFAM AMP-dependent synthetase and ligase
NM966_14075	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NM966_14080	COG0596	Alpha beta hydrolase
NM966_14085	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NM966_14090	COG1169	isochorismate synthase
NM966_14095	COG1575	Belongs to the MenA family. Type 1 subfamily
NM966_14100	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NM966_14230	COG3859	Proton-coupled thiamine transporter YuaJ
NM966_14235	COG1247	-acetyltransferase
NM966_14240	COG3339	Conserved Protein
NM966_14245	COG0772	Belongs to the SEDS family
NM966_14250	COG0772	Belongs to the SEDS family
NM966_14255	COG2268	Band 7 protein
NM966_14260	COG1585	Membrane protein implicated in regulation of membrane protease activity
NM966_14265	COG2318	DinB family
NM966_14270	COG1454	alcohol dehydrogenase
NM966_14275	COG1012	belongs to the aldehyde dehydrogenase family
NM966_14280	COG1510	regulation of RNA biosynthetic process
NM966_14290	COG4974	Belongs to the 'phage' integrase family
NM966_14320	COG3409	Peptidoglycan-binding domain 1 protein
NM966_14320	COG5632	N-Acetylmuramoyl-L-alanine amidase
NM966_14355	COG1705	Flagellar rod assembly protein muramidase FlgJ
NM966_14430	COG0582	viral genome integration into host DNA
NM966_14530	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
NM966_14550	COG0756	dUTP diphosphatase activity
NM966_14565	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NM966_14590	COG1780	Probably involved in ribonucleotide reductase function
NM966_14630	COG2176	DNA-directed DNA polymerase activity
NM966_14635	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NM966_14635	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NM966_14775	COG3409	Peptidoglycan-binding domain 1 protein
NM966_14775	COG5632	N-Acetylmuramoyl-L-alanine amidase
NM966_14830	COG3778	Protein conserved in bacteria
NM966_14835	COG3299	homolog of phage Mu protein gp47
NM966_14840	COG3628	GPW Gp25 family protein
NM966_14850	COG4193	domain, Protein
NM966_14855	COG1652	LysM domain
NM966_14860	COG3953	SLT domain
NM966_14860	COG5280	Phage tail tape measure protein TP901
NM966_14860	COG3953	SLT domain
NM966_14860	COG5280	Phage tail tape measure protein TP901
NM966_14915	COG4653	Phage capsid family
NM966_14920	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NM966_14925	COG5518	Phage portal protein
NM966_14930	COG1783	phage Terminase large subunit
NM966_14935	COG5484	DNA packaging
NM966_14940	COG1595	DNA-templated transcription, initiation
NM966_14950	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
NM966_14970	COG1396	sequence-specific DNA binding
NM966_14980	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NM966_14995	COG0628	permease
NM966_15005	COG0673	inositol 2-dehydrogenase activity
NM966_15010	COG0693	protein deglycase activity
NM966_15015	COG0840	transmembrane signaling receptor activity
NM966_15020	COG0840	transmembrane signaling receptor activity
NM966_15025	COG0840	transmembrane signaling receptor activity
NM966_15030	COG0840	transmembrane signaling receptor activity
NM966_15045	COG2070	2-Nitropropane dioxygenase
NM966_15050	COG0432	Pfam Uncharacterised protein family UPF0047
NM966_15055	COG1253	flavin adenine dinucleotide binding
NM966_15060	COG2738	Putative neutral zinc metallopeptidase
NM966_15070	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NM966_15085	COG0166	Belongs to the GPI family
NM966_15090	COG1979	alcohol dehydrogenase
NM966_15095	COG1979	alcohol dehydrogenase
NM966_15100	COG2155	Conserved Protein
NM966_15105	COG1098	S1 RNA binding domain
NM966_15110	COG0436	Aminotransferase
NM966_15115	COG1522	sequence-specific DNA binding
NM966_15120	COG2267	carboxylic ester hydrolase activity
NM966_15130	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NM966_15135	COG2205	protein histidine kinase activity
NM966_15150	COG5018	Exonuclease
NM966_15155	COG2814	Major facilitator Superfamily
NM966_15160	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NM966_15165	COG3011	Protein conserved in bacteria
NM966_15175	COG3290	protein histidine kinase activity
NM966_15180	COG4565	transcriptional regulatory protein
NM966_15185	COG1744	ABC transporter substrate-binding protein PnrA-like
NM966_15190	COG3845	ABC transporter
NM966_15195	COG4603	Belongs to the binding-protein-dependent transport system permease family
NM966_15200	COG1079	Belongs to the binding-protein-dependent transport system permease family
NM966_15205	COG3493	citrate carrier protein
NM966_15215	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NM966_15215	COG2111	Na H antiporter
NM966_15220	COG2111	Na H antiporter
NM966_15225	COG1006	Multisubunit Na H antiporter MnhC subunit
NM966_15230	COG0651	ATP synthesis coupled electron transport
NM966_15235	COG1863	multisubunit Na H antiporter MnhE subunit
NM966_15240	COG2212	antiporter activity
NM966_15245	COG1320	monovalent cation:proton antiporter activity
NM966_15250	COG2050	protein possibly involved in aromatic compounds catabolism
NM966_15255	COG2197	response regulator
NM966_15260	COG4585	Histidine kinase
NM966_15270	COG0142	geranyltranstransferase activity
NM966_15285	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
NM966_15290	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NM966_15295	COG1335	isochorismatase
NM966_15300	COG5506	Protein of unknown function (DUF1694)
NM966_15320	COG0628	permease
NM966_15335	COG1418	mRNA catabolic process
NM966_15340	COG1028	Short-chain dehydrogenase reductase Sdr
NM966_15350	COG1511	domain protein
NM966_15355	COG0433	COG0433 Predicted ATPase
NM966_15355	COG1674	ftsk spoiiie
NM966_15360	COG4499	WXG100 protein secretion system (Wss), protein YukC
NM966_15365	COG5417	Belongs to the EsaB family
NM966_15370	COG4842	Belongs to the WXG100 family
NM966_15375	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NM966_15375	COG2508	Transcriptional regulator
NM966_15380	COG0686	Belongs to the AlaDH PNT family
NM966_15385	COG1268	BioY protein
NM966_15390	COG2056	Na+-H+ antiporter family
NM966_15395	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NM966_15400	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
NM966_15405	COG3584	3D domain protein
NM966_15420	COG1252	NADH dehydrogenase
NM966_15425	COG0492	ferredoxin-NADP+ reductase activity
NM966_15445	COG0316	Belongs to the HesB IscA family
NM966_15450	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NM966_15455	COG4844	belongs to the
NM966_15460	COG1252	NADH dehydrogenase
NM966_15470	COG4837	Protein of unknown function (DUF1462)
NM966_15480	COG0823	Involved in the tonB-independent uptake of proteins
NM966_15480	COG4946	Tricorn protease homolog
NM966_15480	COG1506	peptidase
NM966_15485	COG0083	homoserine kinase activity
NM966_15490	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NM966_15495	COG0460	homoserine dehydrogenase
NM966_15500	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NM966_15505	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NM966_15510	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NM966_15515	COG0647	UMP catabolic process
NM966_15520	COG2445	Protein of unknown function DUF86
NM966_15525	COG4470	Protein conserved in bacteria
NM966_15535	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NM966_15540	COG0739	heme binding
NM966_15560	COG3377	Domain of unknown function (DUF1805)
NM966_15565	COG0737	Belongs to the 5'-nucleotidase family
NM966_15570	COG1801	Protein of unknown function DUF72
NM966_15575	COG2508	Transcriptional regulator
NM966_15580	COG2140	Oxalate decarboxylase
NM966_15585	COG2814	Major facilitator Superfamily
NM966_15590	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NM966_15595	COG2356	endonuclease I
NM966_15610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NM966_15615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NM966_15620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NM966_15640	COG0642	Histidine kinase
NM966_15640	COG5002	protein histidine kinase activity
NM966_15645	COG0745	RESPONSE REGULATOR receiver
NM966_15650	COG2311	Membrane
NM966_15660	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NM966_15665	COG1090	epimerase
NM966_15670	COG1309	transcriptional regulator
NM966_15675	COG0719	Fe-S assembly protein
NM966_15680	COG0822	iron-sulfur transferase activity
NM966_15685	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NM966_15690	COG0719	Fe-S assembly protein
NM966_15695	COG0396	ATPase activity
NM966_15705	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NM966_15710	COG1464	Belongs to the NlpA lipoprotein family
NM966_15715	COG2011	ABC-type metal ion transport system permease component
NM966_15720	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NM966_15730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NM966_15735	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NM966_15745	COG0509	glycine decarboxylation via glycine cleavage system
NM966_15750	COG1393	Belongs to the ArsC family
NM966_15755	COG1960	acyl-CoA dehydrogenase activity
NM966_15760	COG0183	Belongs to the thiolase family
NM966_15765	COG1024	Enoyl-CoA hydratase
NM966_15765	COG1250	3-hydroxyacyl-CoA dehydrogenase
NM966_15780	COG5577	PFAM Coat F domain
NM966_15790	COG1120	ATPase activity
NM966_15800	COG1028	Short-chain dehydrogenase reductase Sdr
NM966_15805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NM966_15810	COG0745	RESPONSE REGULATOR receiver
NM966_15815	COG2205	protein histidine kinase activity
NM966_15815	COG2770	Histidine kinase
NM966_15825	COG1309	transcriptional regulator
NM966_15830	COG0114	fumarate hydratase activity
NM966_15840	COG0697	spore germination
NM966_15845	COG0814	amino acid
NM966_15860	COG2197	response regulator
NM966_15865	COG4585	Histidine kinase
NM966_15870	COG4758	membrane
NM966_15880	COG1842	Phage shock protein A
NM966_15885	COG4758	membrane
NM966_15890	COG2096	Adenosyltransferase
NM966_15895	COG1028	Short-chain dehydrogenase reductase Sdr
NM966_15900	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NM966_15910	COG3604	Transcriptional regulator
NM966_15925	COG1454	alcohol dehydrogenase
NM966_15930	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NM966_15935	COG1120	ATPase activity
NM966_15940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NM966_15945	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NM966_15955	COG2721	sulfolactate sulfo-lyase activity
NM966_15960	COG0246	Mannitol dehydrogenase
NM966_15965	COG1609	Transcriptional regulator
NM966_15970	COG1904	glucuronate isomerase
NM966_15975	COG2205	protein histidine kinase activity
NM966_15980	COG0745	RESPONSE REGULATOR receiver
NM966_15985	COG1120	ATPase activity
NM966_15990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NM966_15995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NM966_16000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NM966_16005	COG0531	amino acid
NM966_16020	COG1988	membrane-bound metal-dependent
NM966_16025	COG1368	sulfuric ester hydrolase activity
NM966_16030	COG0725	ABC transporter, periplasmic molybdate-binding protein
NM966_16035	COG4149	molybdate abc transporter
NM966_16040	COG0656	L-ascorbic acid biosynthetic process
NM966_16045	COG1940	carbohydrate kinase activity
NM966_16050	COG0025	NhaP-type Na H and K H
NM966_16055	COG2860	membrane
NM966_16060	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NM966_16065	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NM966_16070	COG2217	Heavy metal translocating P-type atpase
NM966_16075	COG1121	(ABC) transporter
NM966_16080	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NM966_16085	COG0803	Belongs to the bacterial solute-binding protein 9 family
NM966_16095	COG3226	Transcriptional regulator
NM966_16100	COG0784	Response regulator, receiver
NM966_16105	COG4191	Histidine kinase
NM966_16110	COG1027	Aspartate ammonia-lyase
NM966_16125	COG2217	Heavy metal translocating P-type atpase
NM966_16130	COG2608	mercury ion transmembrane transporter activity
NM966_16135	COG1937	Protein conserved in bacteria
NM966_16170	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NM966_16175	COG0557	exoribonuclease II activity
NM966_16180	COG1647	Serine aminopeptidase, S33
NM966_16185	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NM966_16190	COG2002	toxin-antitoxin pair type II binding
NM966_16195	COG1476	TRANSCRIPTIONal
NM966_16200	COG1396	sequence-specific DNA binding
NM966_16205	COG1396	sequence-specific DNA binding
NM966_16210	COG1733	regulation of RNA biosynthetic process
NM966_16215	COG1174	glycine betaine transport
NM966_16220	COG1732	Glycine betaine
NM966_16225	COG1174	glycine betaine transport
NM966_16230	COG0517	IMP dehydrogenase activity
NM966_16230	COG1125	glycine betaine transport
NM966_16235	COG1510	regulation of RNA biosynthetic process
NM966_16240	COG2095	MarC family integral membrane protein
NM966_16250	COG0456	acetyltransferase
NM966_16270	COG1131	(ABC) transporter
NM966_16280	COG0148	phosphopyruvate hydratase activity
NM966_16285	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NM966_16290	COG0149	triose-phosphate isomerase activity
NM966_16295	COG0126	phosphoglycerate kinase activity
NM966_16300	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NM966_16305	COG2390	Transcriptional regulator
NM966_16310	COG0833	amino acid
NM966_16315	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NM966_16320	COG3829	transcription factor binding
NM966_16325	COG2186	Transcriptional regulator
NM966_16330	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NM966_16340	COG0534	Mate efflux family protein
NM966_16345	COG4608	Belongs to the ABC transporter superfamily
NM966_16350	COG0444	Belongs to the ABC transporter superfamily
NM966_16355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NM966_16360	COG0601	transmembrane transport
NM966_16365	COG0747	negative chemotaxis
NM966_16370	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NM966_16375	COG0110	maltose O-acetyltransferase activity
NM966_16380	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NM966_16385	COG2244	polysaccharide biosynthetic process
NM966_16390	COG5039	Polysaccharide pyruvyl transferase
NM966_16395	COG1216	Glycosyl transferase, family 2
NM966_16405	COG0438	transferase activity, transferring glycosyl groups
NM966_16410	COG1215	transferase activity, transferring glycosyl groups
NM966_16415	COG0438	transferase activity, transferring glycosyl groups
NM966_16420	COG1086	Polysaccharide biosynthesis protein
NM966_16425	COG0489	protein tyrosine kinase activity
NM966_16430	COG3944	biosynthesis protein
NM966_16435	COG1396	sequence-specific DNA binding
NM966_16445	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NM966_16450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NM966_16455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NM966_16460	COG0726	polysaccharide deacetylase
NM966_16465	COG0488	(ABC) transporter
NM966_16470	COG1819	glycosyl
NM966_16475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NM966_16490	COG0740	serine-type endopeptidase activity
NM966_16495	COG1611	Belongs to the LOG family
NM966_16500	COG1694	Mazg nucleotide pyrophosphohydrolase
NM966_16505	COG0659	secondary active sulfate transmembrane transporter activity
NM966_16510	COG0288	reversible hydration of carbon dioxide
NM966_16515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NM966_16525	COG2162	N-hydroxyarylamine O-acetyltransferase activity
NM966_16530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NM966_16535	COG1481	regulation of sporulation
NM966_16540	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NM966_16545	COG1660	Displays ATPase and GTPase activities
NM966_16550	COG1051	belongs to the nudix hydrolase family
NM966_16555	COG0492	ferredoxin-NADP+ reductase activity
NM966_16560	COG0791	NLP P60 protein
NM966_16560	COG3883	PFAM NLP P60 protein
NM966_16565	COG0457	Tetratricopeptide repeat
NM966_16570	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NM966_16570	COG0140	phosphoribosyl-ATP diphosphatase activity
NM966_16575	COG0107	imidazoleglycerol-phosphate synthase activity
NM966_16580	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NM966_16585	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NM966_16590	COG0131	Imidazoleglycerol-phosphate dehydratase
NM966_16595	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NM966_16600	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NM966_16605	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NM966_16610	COG4990	cell redox homeostasis
NM966_16620	COG2910	NAD(P)H-binding
NM966_16625	COG1959	2 iron, 2 sulfur cluster binding
NM966_16630	COG0110	maltose O-acetyltransferase activity
NM966_16635	COG0546	phosphoglycolate phosphatase activity
NM966_16640	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NM966_16645	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NM966_16650	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NM966_16655	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NM966_16660	COG0363	glucosamine-6-phosphate deaminase activity
NM966_16665	COG2188	Transcriptional regulator
NM966_16670	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NM966_16675	COG1950	PFAM Membrane protein of
NM966_16680	COG1983	PspC domain protein
NM966_16685	COG3595	metallopeptidase activity
NM966_16700	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NM966_16710	COG4897	Protein conserved in bacteria
NM966_16715	COG0574	Belongs to the PEP-utilizing enzyme family
NM966_16715	COG3848	Pyruvate phosphate dikinase
NM966_16720	COG1309	transcriptional regulator
NM966_16725	COG2814	Major facilitator Superfamily
NM966_16735	COG0745	RESPONSE REGULATOR receiver
NM966_16740	COG5002	protein histidine kinase activity
NM966_16745	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NM966_16750	COG0463	Glycosyl transferase, family 2
NM966_16755	COG1113	amino acid transport
NM966_16760	COG0778	Nitroreductase
NM966_16765	COG1733	regulation of RNA biosynthetic process
NM966_16770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NM966_16780	COG0793	Belongs to the peptidase S41A family
NM966_16780	COG3409	Peptidoglycan-binding domain 1 protein
NM966_16785	COG0730	response to heat
NM966_16795	COG3883	PFAM NLP P60 protein
NM966_16795	COG0791	NLP P60 protein
NM966_16800	COG2177	Part of the ABC transporter FtsEX involved in
NM966_16805	COG2884	Cell division ATP-binding protein ftsE
NM966_16810	COG2010	Cytochrome c
NM966_16815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NM966_16835	COG0653	protein targeting
NM966_16840	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NM966_16845	COG0840	transmembrane signaling receptor activity
NM966_16860	COG1516	flagellar protein fliS
NM966_16865	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NM966_16870	COG1334	flagellar protein FlaG
NM966_16875	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NM966_16880	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NM966_16890	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NM966_16895	COG1256	bacterial-type flagellum assembly
NM966_16895	COG4786	Flagellar basal body rod
NM966_16900	COG3418	PFAM FlgN family protein
NM966_16915	COG1040	competence protein
NM966_16925	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NM966_16930	COG1307	EDD domain protein, DegV family
NM966_16935	COG2197	response regulator
NM966_16940	COG4585	Histidine kinase
NM966_16945	COG1739	Uncharacterized protein family UPF0029
NM966_16950	COG1316	TRANSCRIPTIONal
NM966_16955	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NM966_16960	COG0438	transferase activity, transferring glycosyl groups
NM966_16965	COG1215	transferase activity, transferring glycosyl groups
NM966_16970	COG3206	protein involved in exopolysaccharide biosynthesis
NM966_16975	COG3307	-O-antigen
NM966_16980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NM966_16985	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NM966_16990	COG0297	glycogen (starch) synthase activity
NM966_16990	COG0438	transferase activity, transferring glycosyl groups
NM966_16995	COG2244	polysaccharide biosynthetic process
NM966_17010	COG0860	N-Acetylmuramoyl-L-alanine amidase
NM966_17010	COG2247	cell wall binding repeat
NM966_17015	COG2247	cell wall binding repeat
NM966_17015	COG0860	N-Acetylmuramoyl-L-alanine amidase
NM966_17020	COG2385	sporulation resulting in formation of a cellular spore
NM966_17020	COG2247	cell wall binding repeat
NM966_17030	COG1316	TRANSCRIPTIONal
NM966_17035	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NM966_17040	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NM966_17045	COG1134	teichoic acid transport
NM966_17050	COG1682	transport, permease protein
NM966_17060	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NM966_17070	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NM966_17075	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
NM966_17080	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NM966_17085	COG4193	domain, Protein
NM966_17090	COG1482	cell wall glycoprotein biosynthetic process
NM966_17100	COG1175	transmembrane transport
NM966_17105	COG1653	transport
NM966_17110	COG2197	response regulator
NM966_17115	COG2972	Histidine kinase
NM966_17125	COG0454	-acetyltransferase
NM966_17130	COG0800	Aldolase
NM966_17135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NM966_17140	COG1609	Transcriptional regulator
NM966_17145	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NM966_17150	COG1028	Short-chain dehydrogenase reductase Sdr
NM966_17155	COG0697	spore germination
NM966_17160	COG0814	amino acid
NM966_17175	COG2814	Major facilitator Superfamily
NM966_17180	COG1316	TRANSCRIPTIONal
NM966_17185	COG0561	phosphatase activity
NM966_17190	COG0791	NLP P60 protein
NM966_17200	COG2843	Capsule synthesis protein
NM966_17210	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NM966_17215	COG0697	spore germination
NM966_17230	COG1609	Transcriptional regulator
NM966_17235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NM966_17240	COG1869	D-ribose catabolic process
NM966_17245	COG1129	ABC transporter
NM966_17250	COG1172	Belongs to the binding-protein-dependent transport system permease family
NM966_17255	COG1879	ABC-type sugar transport system periplasmic component
NM966_17260	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NM966_17265	COG0583	DNA-binding transcription factor activity
NM966_17270	COG0028	Belongs to the TPP enzyme family
NM966_17275	COG3527	Alpha-acetolactate decarboxylase
NM966_17280	COG1522	sequence-specific DNA binding
NM966_17285	COG2059	Chromate
NM966_17290	COG2059	Chromate
NM966_17295	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NM966_17305	COG4715	Zinc finger, swim domain protein
NM966_17310	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NM966_17315	COG1366	Belongs to the anti-sigma-factor antagonist family
NM966_17315	COG2202	Pas domain
NM966_17320	COG0561	phosphatase activity
NM966_17335	COG1970	mechanosensitive ion channel activity
NM966_17340	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NM966_17345	COG0457	Tetratricopeptide repeat
NM966_17350	COG4786	Flagellar basal body rod
NM966_17355	COG4786	Flagellar basal body rod
NM966_17360	COG1077	Cell shape determining protein MreB Mrl
NM966_17365	COG1609	Transcriptional regulator
NM966_17370	COG1846	Transcriptional regulator
NM966_17375	COG2814	Major facilitator Superfamily
NM966_17380	COG0671	phosphoesterase, PA-phosphatase related
NM966_17385	COG0477	Major facilitator Superfamily
NM966_17390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NM966_17395	COG0765	amino acid transport
NM966_17400	COG1126	abc transporter atp-binding protein
NM966_17405	COG0004	ammonium transporteR
NM966_17410	COG0347	Belongs to the P(II) protein family
NM966_17415	COG0739	heme binding
NM966_17420	COG1247	-acetyltransferase
NM966_17455	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NM966_17460	COG0523	cobalamin synthesis protein
NM966_17465	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NM966_17470	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NM966_17475	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NM966_17480	COG2223	nitrite transmembrane transporter activity
NM966_17490	COG2304	oxidoreductase activity
NM966_17495	COG2304	oxidoreductase activity
NM966_17500	COG2385	sporulation resulting in formation of a cellular spore
NM966_17505	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NM966_17515	COG4836	Membrane
NM966_17525	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NM966_17530	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NM966_17535	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NM966_17540	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NM966_17545	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NM966_17550	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NM966_17555	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NM966_17560	COG0356	it plays a direct role in the translocation of protons across the membrane
NM966_17570	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NM966_17575	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NM966_17580	COG4475	Protein of unknown function (DUF436)
NM966_17585	COG0698	ribose 5-phosphate isomerase
NM966_17590	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NM966_17595	COG1971	Probably functions as a manganese efflux pump
NM966_17600	COG0009	L-threonylcarbamoyladenylate synthase
NM966_17605	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NM966_17620	COG2890	protein-(glutamine-N5) methyltransferase activity
NM966_17625	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NM966_17630	COG0789	Transcriptional regulator
NM966_17635	COG0679	Auxin Efflux Carrier
NM966_17640	COG0281	malic enzyme
NM966_17645	COG1435	thymidine kinase activity
NM966_17650	COG0254	rRNA binding
NM966_17655	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NM966_17660	COG1494	fructose-1,6-bisphosphatase
NM966_17665	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NM966_17670	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NM966_17675	COG0191	fructose-bisphosphate aldolase activity
NM966_17680	COG2204	response regulator
NM966_17685	COG4821	SIS domain
NM966_17690	COG0504	CTP synthase activity
NM966_17695	COG3343	RNA polymerase activity
NM966_17710	COG1960	acyl-CoA dehydrogenase activity
NM966_17715	COG1960	acyl-CoA dehydrogenase activity
NM966_17720	COG1250	3-hydroxyacyl-CoA dehydrogenase
NM966_17725	COG0183	Belongs to the thiolase family
NM966_17730	COG0247	lactate metabolic process
NM966_17730	COG2181	nitrate reductase activity
NM966_17735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NM966_17740	COG4294	response to UV
NM966_17750	COG1619	proteins homologs of microcin C7 resistance protein MccF
NM966_17760	COG1132	(ABC) transporter
NM966_17765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NM966_17770	COG1619	proteins homologs of microcin C7 resistance protein MccF
NM966_17775	COG0018	arginyl-trna synthetase
NM966_17780	COG4506	Protein conserved in bacteria
NM966_17790	COG0010	Belongs to the arginase family
NM966_17795	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NM966_17800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NM966_17810	COG1994	Peptidase M50
NM966_17815	COG1942	4-Oxalocrotonate Tautomerase
NM966_17825	COG3465	dGTPase activity
NM966_17830	COG1078	dGTPase activity
NM966_17835	COG4844	belongs to the
NM966_17885	COG5444	nuclease activity
NM966_17915	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NM966_17925	COG0280	phosphate acetyltransferase
NM966_17935	COG2814	Major facilitator Superfamily
NM966_17940	COG1522	sequence-specific DNA binding
NM966_17945	COG2814	Major facilitator Superfamily
NM966_17950	COG0077	Prephenate dehydratase
NM966_17955	COG1917	Cupin 2, conserved barrel domain protein
NM966_17960	COG1028	Short-chain dehydrogenase reductase Sdr
NM966_17965	COG0151	Belongs to the GarS family
NM966_17970	COG0436	Aminotransferase
NM966_17975	COG1028	Short-chain dehydrogenase reductase Sdr
NM966_17980	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
NM966_17985	COG1091	dTDP-4-dehydrorhamnose reductase activity
NM966_17990	COG1088	dTDP-glucose 4,6-dehydratase activity
NM966_17995	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NM966_18000	COG3980	spore coat polysaccharide biosynthesis protein
NM966_18005	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
NM966_18010	COG2089	acid synthase
NM966_18015	COG0456	acetyltransferase
NM966_18020	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NM966_18025	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NM966_18030	COG0463	Glycosyl transferase, family 2
NM966_18050	COG2363	Small membrane protein
NM966_18055	COG2233	PERMEase
NM966_18065	COG1012	belongs to the aldehyde dehydrogenase family
NM966_18070	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NM966_18075	COG1216	Glycosyl transferase, family 2
NM966_18085	COG0351	phosphomethylpyrimidine kinase
NM966_18100	COG1621	beta-fructofuranosidase activity
NM966_18105	COG1263	PTS System
NM966_18105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NM966_18110	COG3711	transcriptional antiterminator
NM966_18120	COG1404	Belongs to the peptidase S8 family
NM966_18130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NM966_18135	COG0778	Nitroreductase
NM966_18140	COG0772	Belongs to the SEDS family
NM966_18150	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NM966_18155	COG1845	cytochrome c oxidase, subunit III
NM966_18160	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NM966_18165	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NM966_18175	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
NM966_18180	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NM966_18185	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NM966_18200	COG2246	polysaccharide biosynthetic process
NM966_18220	COG3162	membrane
NM966_18225	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NM966_18240	COG0352	thiamine-phosphate diphosphorylase activity
NM966_18245	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NM966_18250	COG0583	DNA-binding transcription factor activity
NM966_18255	COG1380	Effector of murein hydrolase LrgA
NM966_18260	COG1346	cytolysis
NM966_18265	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NM966_18270	COG0346	lactoylglutathione lyase activity
NM966_18280	COG0765	amino acid transport
NM966_18285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NM966_18290	COG0457	Tetratricopeptide repeat
NM966_18300	COG2357	RelA SpoT domain protein
NM966_18305	COG1172	Belongs to the binding-protein-dependent transport system permease family
NM966_18310	COG1129	ABC transporter
NM966_18320	COG3420	alginic acid biosynthetic process
NM966_18325	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NM966_18335	COG1486	melibiose metabolic process
NM966_18340	COG1447	Phosphotransferase system cellobiose-specific component IIA
NM966_18345	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NM966_18350	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NM966_18355	COG3711	transcriptional antiterminator
NM966_18355	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NM966_18375	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NM966_18390	COG1595	DNA-templated transcription, initiation
NM966_18400	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NM966_18405	COG4988	ABC transporter
NM966_18410	COG1294	oxidase, subunit
NM966_18415	COG1271	oxidase subunit
NM966_18430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NM966_18435	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NM966_18440	COG4509	Sortase family
NM966_18465	COG5386	Cell surface protein
NM966_18470	COG5386	Cell surface protein
NM966_18475	COG1733	regulation of RNA biosynthetic process
NM966_18480	COG2514	catechol 2,3-dioxygenase activity
NM966_18485	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NM966_18485	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NM966_18490	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NM966_18490	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NM966_18500	COG0726	polysaccharide deacetylase
NM966_18505	COG1447	Phosphotransferase system cellobiose-specific component IIA
NM966_18510	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NM966_18515	COG2723	6-phospho-beta-galactosidase activity
NM966_18520	COG1312	Catalyzes the dehydration of D-mannonate
NM966_18525	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NM966_18530	COG3711	transcriptional antiterminator
NM966_18530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NM966_18555	COG1757	Na H antiporter
NM966_18560	COG1027	Aspartate ammonia-lyase
NM966_18565	COG0252	asparaginase activity
NM966_18570	COG1396	sequence-specific DNA binding
NM966_18595	COG4842	Belongs to the WXG100 family
NM966_18600	COG2195	Cleaves the N-terminal amino acid of tripeptides
NM966_18615	COG1737	Transcriptional regulator
NM966_18620	COG2084	Dehydrogenase
NM966_18630	COG2610	gluconate transmembrane transporter activity
NM966_18635	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NM966_18640	COG2723	6-phospho-beta-galactosidase activity
NM966_18645	COG1263	PTS System
NM966_18645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NM966_18645	COG2190	(PTS) system
NM966_18650	COG3711	transcriptional antiterminator
NM966_18655	COG3878	Protein conserved in bacteria
NM966_18665	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NM966_18670	COG1122	ATPase activity
NM966_18675	COG4721	ABC-type cobalt transport system, permease component
NM966_18680	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NM966_18715	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NM966_18720	COG0778	Nitroreductase
NM966_18725	COG1846	Transcriptional regulator
NM966_18730	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NM966_18735	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NM966_18740	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NM966_18745	COG2390	Transcriptional regulator
NM966_18755	COG2755	lipolytic protein G-D-S-L family
NM966_18755	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NM966_18760	COG0477	Major facilitator Superfamily
NM966_18765	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NM966_18770	COG2226	methyltransferase
NM966_18780	COG0561	phosphatase activity
NM966_18785	COG0789	Transcriptional regulator
NM966_18790	COG0673	inositol 2-dehydrogenase activity
NM966_18795	COG0840	transmembrane signaling receptor activity
NM966_18800	COG1113	amino acid transport
NM966_18805	COG4335	DNA alkylation repair
NM966_18815	COG1070	Carbohydrate kinase
NM966_18820	COG1737	Transcriptional regulator
NM966_18860	COG0583	DNA-binding transcription factor activity
NM966_18865	COG1609	Transcriptional regulator
NM966_18870	COG2182	Extracellular solute-binding protein
NM966_18875	COG1175	transmembrane transport
NM966_18880	COG3833	ABC-type maltose transport systems, permease component
NM966_18890	COG1874	Beta-galactosidase
NM966_18895	COG2851	Citrate transporter
NM966_18905	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NM966_18910	COG1131	(ABC) transporter
NM966_18915	COG2824	Alkylphosphonate utilization operon protein PhnA
NM966_18920	COG1929	Belongs to the glycerate kinase type-1 family
NM966_18925	COG2610	gluconate transmembrane transporter activity
NM966_18930	COG3835	regulator
NM966_18935	COG1309	transcriptional regulator
NM966_18940	COG2814	Major facilitator Superfamily
NM966_18950	COG1136	(ABC) transporter
NM966_18955	COG0457	Tetratricopeptide repeat
NM966_18960	COG3711	transcriptional antiterminator
NM966_18965	COG2723	6-phospho-beta-galactosidase activity
NM966_18970	COG2190	(PTS) system
NM966_18970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NM966_18970	COG1263	PTS System
NM966_18995	COG0494	nUDIX hydrolase
NM966_19015	COG1113	amino acid transport
NM966_19020	COG1609	Transcriptional regulator
NM966_19025	COG2814	Major facilitator Superfamily
NM966_19030	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NM966_19035	COG2814	Major facilitator Superfamily
NM966_19040	COG2723	6-phospho-beta-galactosidase activity
NM966_19050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NM966_19050	COG2190	(PTS) system
NM966_19050	COG1263	PTS System
NM966_19065	COG5444	nuclease activity
NM966_19085	COG2723	6-phospho-beta-galactosidase activity
NM966_19095	COG2188	Transcriptional regulator
NM966_19105	COG0384	phenazine biosynthesis protein PhzF
NM966_19110	COG0583	DNA-binding transcription factor activity
NM966_19130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NM966_19145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NM966_19155	COG0210	DNA helicase
NM966_19165	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NM966_19175	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NM966_19185	COG4720	Psort location CytoplasmicMembrane, score
NM966_19205	COG0456	acetyltransferase
NM966_19210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NM966_19215	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NM966_19220	COG4853	Protein conserved in bacteria
NM966_19225	COG4863	YycH protein
NM966_19230	COG5002	protein histidine kinase activity
NM966_19235	COG0745	RESPONSE REGULATOR receiver
NM966_19260	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NM966_19270	COG2311	Membrane
NM966_19275	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NM966_19280	COG1309	transcriptional regulator
NM966_19285	COG2124	cytochrome p450
NM966_19290	COG0346	lactoylglutathione lyase activity
NM966_19295	COG0305	Participates in initiation and elongation during chromosome replication
NM966_19310	COG2819	hydrolase of the alpha beta superfamily
NM966_19315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NM966_19315	COG2207	Transcriptional regulator
NM966_19320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NM966_19325	COG2819	hydrolase of the alpha beta superfamily
NM966_19330	COG3093	addiction module antidote protein HigA
NM966_19335	COG2807	transmembrane transport
NM966_19340	COG0359	binds to the 23S rRNA
NM966_19345	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
NM966_19350	COG4241	membrane
NM966_19355	COG1227	inorganic diphosphatase activity
NM966_19365	COG1595	DNA-templated transcription, initiation
NM966_19375	COG0753	catalase activity
NM966_19380	COG0655	NAD(P)H dehydrogenase (quinone) activity
NM966_19385	COG0400	carboxylic ester hydrolase activity
NM966_19390	COG0346	lactoylglutathione lyase activity
NM966_19395	COG1174	glycine betaine transport
NM966_19400	COG0517	IMP dehydrogenase activity
NM966_19400	COG1125	glycine betaine transport
NM966_19405	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NM966_19410	COG0629	single-stranded DNA binding
NM966_19415	COG0360	Binds together with S18 to 16S ribosomal RNA
NM966_19420	COG0012	GTP binding
NM966_19425	COG4481	Protein conserved in bacteria
NM966_19440	COG3949	Membrane
NM966_19450	COG1475	DNA binding
NM966_19455	COG1192	Involved in chromosome partitioning
NM966_19465	COG1475	DNA binding
NM966_19470	COG0357	Ribosomal RNA small subunit methyltransferase G
NM966_19475	COG0445	tRNA wobble uridine modification
NM966_19480	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NM966_19485	COG1847	R3H domain protein
NM966_19490	COG0706	membrane insertase activity
NM966_19495	COG0594	ribonuclease P activity
NM966_19500	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NM966_19505	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NM966_19635	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NM966_19635	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NM966_19645	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NM966_19655	COG1435	thymidine kinase activity
NM966_19665	COG1428	Deoxynucleoside kinase
NM966_19725	COG1191	sigma factor activity
NM966_19790	COG3773	Cell wall hydrolase
NM966_19800	COG1192	Involved in chromosome partitioning