locus-tag	class	description
RI02_00020	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
RI02_00025	COG3853	Toxic anion resistance protein (TelA)
RI02_00030	COG1982	Orn Lys Arg decarboxylase major
RI02_00035	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RI02_00040	COG3870	Protein conserved in bacteria
RI02_00045	COG1728	Protein conserved in bacteria
RI02_00050	COG0470	DNA polymerase III
RI02_00055	COG1774	PSP1 C-terminal conserved region
RI02_00060	COG4467	Involved in initiation control of chromosome replication
RI02_00065	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
RI02_00070	COG2827	Endonuclease containing a URI domain
RI02_00075	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
RI02_00080	COG2002	toxin-antitoxin pair type II binding
RI02_00090	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RI02_00090	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RI02_00095	COG0084	hydrolase, TatD family'
RI02_00100	COG3584	3D domain protein
RI02_00100	COG3583	domain protein
RI02_00105	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
RI02_00110	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RI02_00120	COG4466	Protein conserved in bacteria
RI02_00130	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
RI02_00135	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RI02_00140	COG0251	oxidation-reduction process
RI02_00145	COG2088	sporulation resulting in formation of a cellular spore
RI02_00155	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
RI02_00160	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
RI02_00165	COG0193	aminoacyl-tRNA hydrolase activity
RI02_00175	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
RI02_00180	COG2002	toxin-antitoxin pair type II binding
RI02_00185	COG2244	polysaccharide biosynthetic process
RI02_00190	COG3956	TIGRFAM MazG family protein
RI02_00195	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
RI02_00210	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
RI02_00215	COG1098	S1 RNA binding domain
RI02_00230	COG2208	phosphoserine phosphatase activity
RI02_00235	COG2304	oxidoreductase activity
RI02_00240	COG0515	serine threonine protein kinase
RI02_00245	COG0037	tRNA processing
RI02_00250	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
RI02_00255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RI02_00260	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
RI02_00265	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
RI02_00270	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RI02_00275	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RI02_00280	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RI02_00285	COG0512	Glutamine amidotransferase of anthranilate synthase
RI02_00290	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RI02_00295	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
RI02_00300	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
RI02_00305	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
RI02_00310	COG1396	sequence-specific DNA binding
RI02_00315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RI02_00320	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
RI02_00400	COG4463	regulation of RNA biosynthetic process
RI02_00405	COG3880	PFAM UvrB UvrC protein
RI02_00410	COG3869	Catalyzes the specific phosphorylation of arginine residues in
RI02_00415	COG0542	response to heat
RI02_00420	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
RI02_00425	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
RI02_00430	COG4956	integral membrane protein (PIN domain superfamily)
RI02_00435	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
RI02_00440	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
RI02_00445	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RI02_00450	COG1045	serine acetyltransferase
RI02_00455	COG0215	cysteine-tRNA ligase activity
RI02_00460	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
RI02_00465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RI02_00470	COG3688	RNA-binding protein containing a PIN domain
RI02_00475	COG1595	DNA-templated transcription, initiation
RI02_00480	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RI02_00485	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RI02_00490	COG0250	Participates in transcription elongation, termination and antitermination
RI02_00500	COG0081	regulation of translation
RI02_00505	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
RI02_00510	COG0222	ribosome binding
RI02_00515	COG2813	Specifically methylates the guanine in position
RI02_00520	COG0085	RNA polymerase activity
RI02_00525	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
RI02_00530	COG1358	cellular component organization or biogenesis
RI02_00535	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
RI02_00540	COG0049	tRNA binding
RI02_00545	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RI02_00550	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RI02_00555	COG0596	Alpha beta hydrolase
RI02_00565	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
RI02_00570	COG0088	Forms part of the polypeptide exit tunnel
RI02_00575	COG0089	rRNA binding
RI02_00580	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
RI02_00585	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
RI02_00590	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
RI02_00595	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
RI02_00600	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
RI02_00605	COG0255	Belongs to the universal ribosomal protein uL29 family
RI02_00610	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
RI02_00615	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
RI02_00620	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
RI02_00625	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
RI02_00630	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
RI02_00635	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
RI02_00640	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
RI02_00645	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
RI02_00650	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
RI02_00655	COG1841	ribosomal large subunit assembly
RI02_00660	COG0200	Binds to the 23S rRNA
RI02_00665	COG0201	protein transport
RI02_00670	COG0563	adenylate kinase activity
RI02_00675	COG0024	Methionine aminopeptidase
RI02_00685	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
RI02_00690	COG0257	Belongs to the bacterial ribosomal protein bL36 family
RI02_00695	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
RI02_00700	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
RI02_00705	COG0202	RNA polymerase activity
RI02_00710	COG0203	ribosomal protein L17
RI02_00715	COG1122	ATPase activity
RI02_00720	COG1122	ATPase activity
RI02_00725	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RI02_00730	COG0101	tRNA pseudouridine synthase activity
RI02_00735	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
RI02_00740	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
RI02_00745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RI02_00770	COG1136	(ABC) transporter
RI02_00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
RI02_00795	COG0489	protein tyrosine kinase activity
RI02_00805	COG2194	sulfuric ester hydrolase activity
RI02_00810	COG0726	polysaccharide deacetylase
RI02_00840	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RI02_00845	COG0659	secondary active sulfate transmembrane transporter activity
RI02_00850	COG0385	Bile acid
RI02_00855	COG3876	Protein conserved in bacteria
RI02_00860	COG1472	Belongs to the glycosyl hydrolase 3 family
RI02_00865	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RI02_00870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RI02_00870	COG1263	PTS System
RI02_00875	COG1737	Transcriptional regulator
RI02_00880	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
RI02_00915	COG1595	DNA-templated transcription, initiation
RI02_00920	COG5662	AntiSigma factor
RI02_00925	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
RI02_00930	COG4856	YbbR-like protein
RI02_00935	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RI02_00940	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RI02_00960	COG1131	(ABC) transporter
RI02_00970	COG1136	(ABC) transporter
RI02_00980	COG1695	Transcriptional regulator
RI02_00995	COG0535	radical SAM domain protein
RI02_01000	COG1266	CAAX protease self-immunity
RI02_01005	COG1131	(ABC) transporter
RI02_01015	COG1413	lyase activity
RI02_01020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RI02_01030	COG2311	Membrane
RI02_01050	COG1476	TRANSCRIPTIONal
RI02_01060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RI02_01065	COG2207	Transcriptional regulator
RI02_01080	COG1131	(ABC) transporter
RI02_01095	COG1113	amino acid transport
RI02_01100	COG0584	glycerophosphoryl diester phosphodiesterase
RI02_01105	COG2271	Major facilitator Superfamily
RI02_01115	COG1331	Highly conserved protein containing a thioredoxin domain
RI02_01120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RI02_01135	COG0640	Transcriptional regulator
RI02_01150	COG1937	Protein conserved in bacteria
RI02_01155	COG2210	Belongs to the sulfur carrier protein TusA family
RI02_01165	COG0425	Belongs to the sulfur carrier protein TusA family
RI02_01165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RI02_01170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RI02_01170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RI02_01175	COG0425	Belongs to the sulfur carrier protein TusA family
RI02_01180	COG0730	response to heat
RI02_01190	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RI02_01195	COG2814	Major facilitator Superfamily
RI02_01210	COG1846	Transcriptional regulator
RI02_01220	COG1683	Conserved Protein
RI02_01235	COG0656	L-ascorbic acid biosynthetic process
RI02_01240	COG0371	Dehydrogenase
RI02_01245	COG1054	Belongs to the UPF0176 family
RI02_01250	COG0531	amino acid
RI02_01260	COG3711	transcriptional antiterminator
RI02_01265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RI02_01265	COG2190	(PTS) system
RI02_01265	COG1263	PTS System
RI02_01270	COG2723	6-phospho-beta-galactosidase activity
RI02_01285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RI02_01285	COG3711	transcriptional antiterminator
RI02_01290	COG1940	carbohydrate kinase activity
RI02_01295	COG0383	alpha-mannosidase activity
RI02_01300	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RI02_01305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RI02_01315	COG1404	Belongs to the peptidase S8 family
RI02_01330	COG0833	amino acid
RI02_01335	COG2040	homocysteine
RI02_01340	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RI02_01365	COG2814	Major facilitator Superfamily
RI02_01370	COG0456	acetyltransferase
RI02_01385	COG1404	Belongs to the peptidase S8 family
RI02_01395	COG1309	transcriptional regulator
RI02_01400	COG1917	Cupin 2, conserved barrel domain protein
RI02_01405	COG1846	Transcriptional regulator
RI02_01410	COG0318	PFAM AMP-dependent synthetase and ligase
RI02_01415	COG0531	amino acid
RI02_01425	COG0596	Alpha beta hydrolase
RI02_01430	COG1115	amino acid carrier protein
RI02_01435	COG2066	Belongs to the glutaminase family
RI02_01440	COG4191	Histidine kinase
RI02_01445	COG0784	Response regulator, receiver
RI02_01450	COG3012	SEC-C Motif Domain Protein
RI02_01450	COG1405	negative regulation of cell septum assembly
RI02_01460	COG0667	Aldo Keto reductase
RI02_01465	COG3290	protein histidine kinase activity
RI02_01470	COG3279	Response regulator of the LytR AlgR family
RI02_01475	COG4555	ABC transporter
RI02_01480	COG1668	transmembrane transport
RI02_01500	COG3773	Cell wall hydrolase
RI02_01505	COG1028	Short-chain dehydrogenase reductase Sdr
RI02_01515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RI02_01520	COG2310	stress, protein
RI02_01525	COG2310	stress, protein
RI02_01530	COG2310	stress, protein
RI02_01535	COG0861	Integral membrane protein TerC family
RI02_01565	COG3853	Toxic anion resistance protein (TelA)
RI02_01570	COG0517	IMP dehydrogenase activity
RI02_01570	COG4175	Glycine betaine
RI02_01575	COG4176	ABC-type proline glycine betaine transport system permease component
RI02_01580	COG2113	Glycine betaine
RI02_01595	COG1473	amidohydrolase
RI02_01600	COG1288	antiporter activity
RI02_01605	COG0039	L-malate dehydrogenase activity
RI02_01610	COG1620	l-lactate permease
RI02_01615	COG1609	Transcriptional regulator
RI02_01620	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RI02_01625	COG0561	phosphatase activity
RI02_01630	COG0673	inositol 2-dehydrogenase activity
RI02_01635	COG0738	Major facilitator superfamily
RI02_01640	COG1280	lysine exporter protein (LysE YggA)
RI02_01655	COG3403	YqcI/YcgG family
RI02_01660	COG1113	amino acid transport
RI02_01665	COG3665	Urea carboxylase-associated protein
RI02_01670	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
RI02_01680	COG1012	belongs to the aldehyde dehydrogenase family
RI02_01685	COG0710	3-dehydroquinate dehydratase activity
RI02_01690	COG0028	Belongs to the TPP enzyme family
RI02_01700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RI02_01705	COG2271	Major facilitator Superfamily
RI02_01720	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RI02_01725	COG2226	methyltransferase
RI02_01730	COG0583	DNA-binding transcription factor activity
RI02_01735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RI02_01740	COG3458	cephalosporin-C deacetylase activity
RI02_01750	COG3541	Predicted nucleotidyltransferase
RI02_01755	COG0506	proline dehydrogenase activity
RI02_01760	COG1012	belongs to the aldehyde dehydrogenase family
RI02_01765	COG2508	Transcriptional regulator
RI02_01770	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
RI02_01775	COG0765	amino acid transport
RI02_01780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RI02_01790	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RI02_01795	COG1522	sequence-specific DNA binding
RI02_01800	COG2746	aminoglycoside 3-N-acetyltransferase activity
RI02_01810	COG3290	protein histidine kinase activity
RI02_01810	COG0840	transmembrane signaling receptor activity
RI02_01815	COG3209	COG3209 Rhs family protein
RI02_01840	COG3842	ATPase activity
RI02_01845	COG1176	ABC-type spermidine putrescine transport system, permease component I
RI02_01855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RI02_01860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RI02_01865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RI02_01880	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
RI02_01885	COG0697	spore germination
RI02_01890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RI02_01900	COG3708	Transcriptional regulator
RI02_01900	COG2207	Transcriptional regulator
RI02_01910	COG2364	Membrane
RI02_01915	COG1126	abc transporter atp-binding protein
RI02_01920	COG0765	amino acid transport
RI02_01925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RI02_01930	COG0412	Dienelactone hydrolase
RI02_01935	COG0833	amino acid
RI02_01940	COG3104	oligopeptide transport
RI02_01945	COG5434	Belongs to the glycosyl hydrolase 28 family
RI02_01950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RI02_01955	COG0456	acetyltransferase
RI02_01960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RI02_01965	COG0765	amino acid transport
RI02_01970	COG1126	abc transporter atp-binding protein
RI02_01975	COG1473	amidohydrolase
RI02_01980	COG2079	MmgE PrpD family protein
RI02_01990	COG0745	RESPONSE REGULATOR receiver
RI02_01995	COG3850	Histidine kinase
RI02_01995	COG5002	protein histidine kinase activity
RI02_02000	COG1366	Belongs to the anti-sigma-factor antagonist family
RI02_02005	COG0527	aspartate kinase activity
RI02_02010	COG2814	Major facilitator Superfamily
RI02_02015	COG1309	transcriptional regulator
RI02_02025	COG0640	Transcriptional regulator
RI02_02035	COG0583	DNA-binding transcription factor activity
RI02_02040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RI02_02045	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RI02_02050	COG0531	amino acid
RI02_02055	COG1012	belongs to the aldehyde dehydrogenase family
RI02_02060	COG2249	NAD(P)H dehydrogenase (quinone) activity
RI02_02065	COG4549	nuclear export factor GLE1
RI02_02070	COG1276	copper resistance
RI02_02070	COG2372	response to copper ion
RI02_02075	COG2213	PTS system mannitol-specific
RI02_02080	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
RI02_02085	COG0246	Mannitol dehydrogenase
RI02_02090	COG0840	transmembrane signaling receptor activity
RI02_02125	COG0346	lactoylglutathione lyase activity
RI02_02135	COG0561	phosphatase activity
RI02_02140	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
RI02_02145	COG1914	H( )-stimulated, divalent metal cation uptake system
RI02_02150	COG4336	lyase activity
RI02_02155	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
RI02_02160	COG1984	allophanate hydrolase subunit 2
RI02_02165	COG1414	Transcriptional regulator
RI02_02170	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RI02_02175	COG2755	lipolytic protein G-D-S-L family
RI02_02185	COG3711	transcriptional antiterminator
RI02_02190	COG2226	methyltransferase
RI02_02195	COG1028	Short-chain dehydrogenase reductase Sdr
RI02_02200	COG3871	stress protein (general stress protein 26)
RI02_02220	COG2814	Major facilitator Superfamily
RI02_02225	COG1802	Transcriptional regulator
RI02_02230	COG1917	Cupin 2, conserved barrel domain protein
RI02_02230	COG2207	Transcriptional regulator
RI02_02235	COG0697	spore germination
RI02_02240	COG0473	3-isopropylmalate dehydrogenase activity
RI02_02245	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RI02_02245	COG0551	DNA topoisomerase type I activity
RI02_02250	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
RI02_02255	COG3706	GGDEF domain
RI02_02260	COG5298	Protein conserved in bacteria
RI02_02265	COG1215	transferase activity, transferring glycosyl groups
RI02_02275	COG0531	amino acid
RI02_02280	COG0028	Belongs to the TPP enzyme family
RI02_02285	COG5444	nuclease activity
RI02_02315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RI02_02320	COG1914	H( )-stimulated, divalent metal cation uptake system
RI02_02325	COG2261	transglycosylase associated protein
RI02_02330	COG2217	Heavy metal translocating P-type atpase
RI02_02335	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RI02_02340	COG3290	protein histidine kinase activity
RI02_02345	COG4565	transcriptional regulatory protein
RI02_02350	COG1301	dicarboxylic acid transport
RI02_02355	COG0628	permease
RI02_02360	COG1301	dicarboxylic acid transport
RI02_02365	COG1131	(ABC) transporter
RI02_02370	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
RI02_02385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RI02_02390	COG1181	Belongs to the D-alanine--D-alanine ligase family
RI02_02395	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
RI02_02410	COG0513	Belongs to the DEAD box helicase family
RI02_02415	COG3402	PFAM membrane-flanked domain
RI02_02420	COG3428	Bacterial PH domain
RI02_02425	COG0705	Rhomboid family
RI02_02430	COG0736	holo-[acyl-carrier-protein] synthase activity
RI02_02435	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
RI02_02440	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RI02_02445	COG0864	Transcriptional regulator
RI02_02450	COG2337	Toxic component of a toxin-antitoxin (TA) module
RI02_02455	COG1366	Belongs to the anti-sigma-factor antagonist family
RI02_02460	COG1366	Belongs to the anti-sigma-factor antagonist family
RI02_02465	COG2172	sigma factor antagonist activity
RI02_02470	COG2208	phosphoserine phosphatase activity
RI02_02475	COG1366	Belongs to the anti-sigma-factor antagonist family
RI02_02480	COG2172	sigma factor antagonist activity
RI02_02485	COG1191	sigma factor activity
RI02_02490	COG2208	phosphoserine phosphatase activity
RI02_02495	COG2183	response to ionizing radiation
RI02_02505	COG3091	SprT-like family
RI02_02510	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RI02_02515	COG0022	dehydrogenase e1 component
RI02_02520	COG0508	dehydrogenase complex catalyzes the overall conversion of
RI02_02525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RI02_02530	COG3284	Transcriptional regulator
RI02_02575	COG1278	Cold shock
RI02_02580	COG1263	PTS System
RI02_02580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RI02_02580	COG2190	(PTS) system
RI02_02585	COG3394	polysaccharide catabolic process
RI02_02590	COG3711	transcriptional antiterminator
RI02_02595	COG1064	alcohol dehydrogenase
RI02_02600	COG0789	Transcriptional regulator
RI02_02620	COG0477	Major facilitator Superfamily
RI02_02625	COG0657	acetylesterase activity
RI02_02635	COG4221	oxidoreductase activity
RI02_02645	COG0252	asparaginase activity
RI02_02650	COG2267	carboxylic ester hydrolase activity
RI02_02665	COG2814	Major facilitator Superfamily
RI02_02670	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
RI02_02675	COG2409	Drug exporters of the RND superfamily
RI02_02680	COG4585	Histidine kinase
RI02_02685	COG2197	response regulator
RI02_02730	COG1309	transcriptional regulator
RI02_02735	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
RI02_02740	COG1846	Transcriptional regulator
RI02_02745	COG0778	Nitroreductase
RI02_02760	COG1396	sequence-specific DNA binding
RI02_02770	COG0456	acetyltransferase
RI02_02785	COG4122	O-methyltransferase activity
RI02_02795	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
RI02_02800	COG0697	spore germination
RI02_02810	COG1301	dicarboxylic acid transport
RI02_02850	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
RI02_02855	COG0802	atpase or kinase
RI02_02860	COG1214	PFAM Peptidase M22, glycoprotease
RI02_02865	COG0456	acetyltransferase
RI02_02870	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
RI02_02875	COG0488	(ABC) transporter
RI02_02880	COG0315	cyclic pyranopterin monophosphate synthase activity
RI02_02885	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
RI02_02890	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RI02_02895	COG0805	protein transport
RI02_02910	COG1266	CAAX protease self-immunity
RI02_02915	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
RI02_02920	COG0459	protein refolding
RI02_02925	COG1846	Transcriptional regulator
RI02_02930	COG0456	acetyltransferase
RI02_02935	COG2808	Putative FMN-binding domain
RI02_02940	COG1876	peptidase activity
RI02_02965	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
RI02_02970	COG0823	Involved in the tonB-independent uptake of proteins
RI02_02980	COG2132	Multicopper oxidase
RI02_02985	COG1113	amino acid transport
RI02_02990	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
RI02_02995	COG0714	Associated with various cellular activities
RI02_03000	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
RI02_03005	COG1305	Transglutaminase-like
RI02_03010	COG0519	Catalyzes the synthesis of GMP from XMP
RI02_03010	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RI02_03035	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RI02_03045	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RI02_03080	COG3279	Response regulator of the LytR AlgR family
RI02_03100	COG1595	DNA-templated transcription, initiation
RI02_03110	COG2814	Major facilitator Superfamily
RI02_03115	COG0583	DNA-binding transcription factor activity
RI02_03120	COG2252	PERMEase
RI02_03125	COG5583	Uncharacterized small protein (DUF2292)
RI02_03130	COG3064	Membrane
RI02_03135	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
RI02_03145	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RI02_03150	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
RI02_03155	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RI02_03160	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
RI02_03165	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RI02_03170	COG0047	phosphoribosylformylglycinamidine synthase activity
RI02_03175	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RI02_03180	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
RI02_03185	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
RI02_03190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
RI02_03195	COG0138	bifunctional purine biosynthesis protein purh
RI02_03200	COG0151	Belongs to the GarS family
RI02_03220	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RI02_03225	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
RI02_03230	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RI02_03235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RI02_03245	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
RI02_03250	COG4496	protein, YerC YecD
RI02_03260	COG0069	glutamate synthase activity
RI02_03275	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
RI02_03280	COG0210	DNA helicase
RI02_03285	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RI02_03290	COG4851	CamS sex pheromone cAM373 precursor
RI02_03295	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RI02_03300	COG1285	pathogenesis
RI02_03305	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RI02_03310	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RI02_03315	COG0154	amidase activity
RI02_03320	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RI02_03325	COG1309	transcriptional regulator
RI02_03330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RI02_03335	COG1957	nucleoside hydrolase
RI02_03340	COG1597	lipid kinase activity
RI02_03345	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RI02_03370	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RI02_03385	COG1959	2 iron, 2 sulfur cluster binding
RI02_03390	COG0492	ferredoxin-NADP+ reductase activity
RI02_03405	COG1486	melibiose metabolic process
RI02_03415	COG2211	Major facilitator Superfamily
RI02_03445	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
RI02_03450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RI02_03455	COG1442	glycosyl transferase family 8
RI02_03460	COG1216	Glycosyl transferase, family 2
RI02_03465	COG1442	glycosyl transferase family 8
RI02_03470	COG2223	nitrite transmembrane transporter activity
RI02_03480	COG0471	metal ion transport
RI02_03495	COG0071	Belongs to the small heat shock protein (HSP20) family
RI02_03510	COG0531	amino acid
RI02_03515	COG0457	Tetratricopeptide repeat
RI02_03515	COG0463	Glycosyl transferase, family 2
RI02_03520	COG0488	(ABC) transporter
RI02_03525	COG1469	GTP cyclohydrolase I activity
RI02_03530	COG0789	Transcriptional regulator
RI02_03535	COG2814	Major facilitator Superfamily
RI02_03540	COG0488	(ABC) transporter
RI02_03545	COG0513	Belongs to the DEAD box helicase family
RI02_03550	COG2130	NADP-dependent
RI02_03570	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RI02_03570	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RI02_03575	COG1262	PFAM Formylglycine-generating sulfatase enzyme
RI02_03585	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RI02_03585	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RI02_03595	COG3290	protein histidine kinase activity
RI02_03600	COG4565	transcriptional regulatory protein
RI02_03605	COG3181	Tripartite tricarboxylate transporter family receptor
RI02_03610	COG2851	Citrate transporter
RI02_03620	COG3479	Phenolic acid decarboxylase
RI02_03625	COG1695	Transcriptional regulator
RI02_03630	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
RI02_03640	COG1254	Belongs to the acylphosphatase family
RI02_03645	COG2258	MOSC domain
RI02_03660	COG0024	Methionine aminopeptidase
RI02_03665	COG1263	PTS System
RI02_03665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RI02_03670	COG3739	integral membrane protein
RI02_03685	COG1368	sulfuric ester hydrolase activity
RI02_03690	COG0076	glutamate decarboxylase activity
RI02_03705	COG1263	PTS System
RI02_03705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RI02_03710	COG0366	Alpha amylase catalytic
RI02_03715	COG2188	Transcriptional regulator
RI02_03725	COG0737	Belongs to the 5'-nucleotidase family
RI02_03730	COG0693	protein deglycase activity
RI02_03735	COG4840	Belongs to the UPF0435 family
RI02_03740	COG1115	amino acid carrier protein
RI02_03750	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RI02_03755	COG4980	gas vesicle protein
RI02_03760	COG1295	ribonuclease BN
RI02_03765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RI02_03770	COG0477	Major facilitator Superfamily
RI02_03780	COG0387	Pfam Sodium calcium exchanger
RI02_03795	COG0217	transcriptional regulatory protein
RI02_03805	COG0668	transmembrane transport
RI02_03810	COG0535	radical SAM domain protein
RI02_03820	COG0726	polysaccharide deacetylase
RI02_03830	COG0598	Magnesium transport protein CorA
RI02_03840	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
RI02_03845	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RI02_03865	COG0789	Transcriptional regulator
RI02_03870	COG2814	Major facilitator Superfamily
RI02_03925	COG2076	Multidrug Resistance protein
RI02_03930	COG2076	Multidrug Resistance protein
RI02_03935	COG1309	transcriptional regulator
RI02_03945	COG4637	Psort location Cytoplasmic, score
RI02_03950	COG2755	lipolytic protein G-D-S-L family
RI02_03955	COG0492	ferredoxin-NADP+ reductase activity
RI02_03960	COG2169	Transcriptional regulator
RI02_03965	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
RI02_03970	COG1132	(ABC) transporter
RI02_03975	COG1742	UPF0060 membrane protein
RI02_03980	COG1595	DNA-templated transcription, initiation
RI02_04000	COG2318	DinB family
RI02_04010	COG1846	Transcriptional regulator
RI02_04015	COG0392	lysyltransferase activity
RI02_04015	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
RI02_04035	COG0778	Nitroreductase
RI02_04050	COG1090	epimerase
RI02_04055	COG2137	regulation of response to DNA damage stimulus
RI02_04080	COG0463	Glycosyl transferase, family 2
RI02_04085	COG4485	Bacterial membrane protein, YfhO
RI02_04090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RI02_04105	COG2140	Oxalate decarboxylase
RI02_04115	COG1191	sigma factor activity
RI02_04125	COG1988	membrane-bound metal-dependent
RI02_04130	COG1194	a g-specific adenine glycosylase
RI02_04140	COG1028	Short-chain dehydrogenase reductase Sdr
RI02_04155	COG3557	Belongs to the UPF0374 family
RI02_04160	COG1132	(ABC) transporter
RI02_04165	COG0444	Belongs to the ABC transporter superfamily
RI02_04170	COG4608	Belongs to the ABC transporter superfamily
RI02_04175	COG0747	negative chemotaxis
RI02_04180	COG0601	transmembrane transport
RI02_04185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RI02_04190	COG4129	membrane
RI02_04195	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
RI02_04200	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RI02_04205	COG0735	belongs to the Fur family
RI02_04350	COG1368	sulfuric ester hydrolase activity
RI02_04355	COG0681	Belongs to the peptidase S26 family
RI02_04360	COG2873	o-acetylhomoserine
RI02_04370	COG1116	anion transmembrane transporter activity
RI02_04375	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RI02_04380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RI02_04395	COG1131	(ABC) transporter
RI02_04425	COG3382	B3 4 domain protein
RI02_04430	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RI02_04440	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
RI02_04445	COG2766	serine protein kinase
RI02_04450	COG2718	Belongs to the UPF0229 family
RI02_04455	COG1566	PFAM secretion protein HlyD family protein
RI02_04460	COG2814	Major facilitator Superfamily
RI02_04465	COG0655	NAD(P)H dehydrogenase (quinone) activity
RI02_04475	COG1278	Cold shock
RI02_04485	COG3706	GGDEF domain
RI02_04510	COG5577	PFAM Coat F domain
RI02_04515	COG5002	protein histidine kinase activity
RI02_04520	COG4085	toxin activity
RI02_04520	COG0737	Belongs to the 5'-nucleotidase family
RI02_04520	COG1525	nuclease
RI02_04525	COG3764	Sortase (surface protein transpeptidase)
RI02_04530	COG0564	pseudouridine synthase activity
RI02_04540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RI02_04545	COG3153	acetyltransferase
RI02_04545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RI02_04565	COG3835	regulator
RI02_04570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RI02_04575	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
RI02_04580	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
RI02_04585	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RI02_04590	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
RI02_04595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RI02_04600	COG2203	Gaf domain
RI02_04600	COG4585	Histidine kinase
RI02_04605	COG2197	response regulator
RI02_04620	COG0753	catalase activity
RI02_04625	COG1959	2 iron, 2 sulfur cluster binding
RI02_04630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RI02_04630	COG1017	nitric oxide dioxygenase activity
RI02_04635	COG2719	SpoVR family
RI02_04640	COG1785	Belongs to the alkaline phosphatase family
RI02_04645	COG1388	LysM domain
RI02_04645	COG0791	NLP P60 protein
RI02_04650	COG0531	amino acid
RI02_04665	COG1595	DNA-templated transcription, initiation
RI02_04670	COG0204	Acyl-transferase
RI02_04675	COG1253	flavin adenine dinucleotide binding
RI02_04680	COG0789	Transcriptional regulator
RI02_04685	COG1253	flavin adenine dinucleotide binding
RI02_04700	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RI02_04705	COG0584	glycerophosphoryl diester phosphodiesterase
RI02_04715	COG0668	transmembrane transport
RI02_04720	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
RI02_04725	COG0726	polysaccharide deacetylase
RI02_04730	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RI02_04740	COG0589	response to stress
RI02_04745	COG1132	(ABC) transporter
RI02_04750	COG1132	(ABC) transporter
RI02_04755	COG0702	epimerase
RI02_04765	COG3842	ATPase activity
RI02_04770	COG2508	Transcriptional regulator
RI02_04780	COG0189	ligase activity
RI02_04785	COG0189	ligase activity
RI02_04790	COG4399	Belongs to the UPF0754 family
RI02_04795	COG3679	Belongs to the UPF0342 family
RI02_04800	COG0561	phosphatase activity
RI02_04805	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RI02_04815	COG0475	glutathione-regulated potassium exporter activity
RI02_04820	COG0490	domain, Protein
RI02_04830	COG1024	Enoyl-CoA hydratase
RI02_04840	COG0420	3'-5' exonuclease activity
RI02_04845	COG4717	serine-type aminopeptidase activity
RI02_04850	COG3481	metal-dependent phosphohydrolase, HD sub domain
RI02_04860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RI02_04890	COG1846	Transcriptional regulator
RI02_04895	COG4980	gas vesicle protein
RI02_04910	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
RI02_04915	COG0537	adenosine 5'-monophosphoramidase activity
RI02_04920	COG1131	(ABC) transporter
RI02_04925	COG4473	ABC transporter
RI02_04935	COG1473	amidohydrolase
RI02_04950	COG2329	Antibiotic biosynthesis monooxygenase
RI02_04955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RI02_04960	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
RI02_04965	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
RI02_04970	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
RI02_04975	COG1309	transcriptional regulator
RI02_04980	COG1511	domain protein
RI02_04985	COG1363	Peptidase, m42
RI02_04990	COG1301	dicarboxylic acid transport
RI02_05000	COG1234	tRNA 3'-trailer cleavage
RI02_05005	COG0095	Lipoate-protein ligase
RI02_05010	COG0318	PFAM AMP-dependent synthetase and ligase
RI02_05020	COG0501	Belongs to the peptidase M48B family
RI02_05025	COG1404	Belongs to the peptidase S8 family
RI02_05030	COG0406	alpha-ribazole phosphatase activity
RI02_05035	COG0840	transmembrane signaling receptor activity
RI02_05040	COG0723	plastoquinol--plastocyanin reductase activity
RI02_05040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RI02_05045	COG1028	Short-chain dehydrogenase reductase Sdr
RI02_05055	COG4903	ComK protein
RI02_05070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RI02_05075	COG2814	Major facilitator Superfamily
RI02_05080	COG2732	(Barnase) inhibitor
RI02_05085	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RI02_05090	COG4605	iron ion homeostasis
RI02_05095	COG4604	ABC transporter, ATP-binding protein
RI02_05100	COG4607	ABC-type enterochelin transport system periplasmic component
RI02_05105	COG1316	TRANSCRIPTIONal
RI02_05125	COG0398	Pfam SNARE associated Golgi protein
RI02_05130	COG0681	Belongs to the peptidase S26 family
RI02_05140	COG3180	Ammonia monooxygenase
RI02_05155	COG2259	Doxx family
RI02_05160	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
RI02_05165	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
RI02_05170	COG1074	ATP-dependent DNA helicase activity
RI02_05175	COG0420	3'-5' exonuclease activity
RI02_05180	COG0419	ATPase involved in DNA repair
RI02_05185	COG1403	HNH endonuclease
RI02_05225	COG5337	Spore coat protein CotH
RI02_05240	COG0179	Fumarylacetoacetate (FAA) hydrolase
RI02_05255	COG0367	asparagine synthase
RI02_05270	COG1562	ergosterol biosynthetic process
RI02_05275	COG0534	Mate efflux family protein
RI02_05280	COG1917	Cupin 2, conserved barrel domain protein
RI02_05280	COG2207	Transcriptional regulator
RI02_05305	COG0076	glutamate decarboxylase activity
RI02_05340	COG0646	methionine synthase
RI02_05340	COG1410	methionine synthase
RI02_05345	COG0646	methionine synthase
RI02_05345	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
RI02_05350	COG1666	GTP binding
RI02_05355	COG2996	Protein conserved in bacteria
RI02_05360	COG1744	ABC transporter substrate-binding protein PnrA-like
RI02_05365	COG0840	transmembrane signaling receptor activity
RI02_05370	COG1307	EDD domain protein, DegV family
RI02_05375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RI02_05395	COG0561	phosphatase activity
RI02_05400	COG1073	alpha beta
RI02_05405	COG2151	metal-sulfur cluster biosynthetic enzyme
RI02_05410	COG0277	FAD linked oxidase domain protein
RI02_05415	COG2271	Major facilitator Superfamily
RI02_05420	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
RI02_05425	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
RI02_05430	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
RI02_05435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RI02_05440	COG0505	Belongs to the CarA family
RI02_05445	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RI02_05450	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
RI02_05460	COG2814	Major facilitator Superfamily
RI02_05470	COG2267	carboxylic ester hydrolase activity
RI02_05480	COG1744	ABC transporter substrate-binding protein PnrA-like
RI02_05495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RI02_05500	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RI02_05505	COG5504	Zn-dependent protease
RI02_05510	COG0444	Belongs to the ABC transporter superfamily
RI02_05515	COG4608	Belongs to the ABC transporter superfamily
RI02_05525	COG0601	transmembrane transport
RI02_05530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RI02_05540	COG0180	Tryptophanyl-tRNA synthetase
RI02_05545	COG4166	transmembrane transport
RI02_05550	COG0601	transmembrane transport
RI02_05555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RI02_05560	COG0444	Belongs to the ABC transporter superfamily
RI02_05565	COG4608	Belongs to the ABC transporter superfamily
RI02_05575	COG0456	acetyltransferase
RI02_05580	COG1393	Belongs to the ArsC family
RI02_05585	COG0861	Integral membrane protein TerC family
RI02_05590	COG4862	establishment of competence for transformation
RI02_05595	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RI02_05605	COG1164	Oligoendopeptidase f
RI02_05615	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
RI02_05620	COG2346	COG2346, Truncated hemoglobins
RI02_05625	COG0741	lytic transglycosylase activity
RI02_05630	COG4116	CYTH
RI02_05640	COG2357	RelA SpoT domain protein
RI02_05645	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RI02_05650	COG0564	pseudouridine synthase activity
RI02_05655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RI02_05660	COG0475	glutathione-regulated potassium exporter activity
RI02_05660	COG0569	domain protein
RI02_05665	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
RI02_05670	COG0352	thiamine-phosphate diphosphorylase activity
RI02_05680	COG2104	thiamine diphosphate biosynthetic process
RI02_05685	COG2022	thiamine diphosphate biosynthetic process
RI02_05690	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RI02_05695	COG0351	phosphomethylpyrimidine kinase
RI02_05700	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
RI02_05755	COG0210	DNA helicase
RI02_05765	COG2153	protein acetylation
RI02_05770	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
RI02_05775	COG2382	esterase
RI02_05780	COG0626	cystathionine gamma-synthase activity
RI02_05785	COG0626	cystathionine gamma-synthase activity
RI02_05795	COG3620	sequence-specific DNA binding
RI02_05810	COG0825	malonyl-CoA metabolic process
RI02_05825	COG0457	Tetratricopeptide repeat
RI02_05835	COG1280	lysine exporter protein (LysE YggA)
RI02_05845	COG2364	Membrane
RI02_05880	COG3173	Aminoglycoside phosphotransferase
RI02_05885	COG0583	DNA-binding transcription factor activity
RI02_05905	COG0583	DNA-binding transcription factor activity
RI02_05910	COG2807	transmembrane transport
RI02_05940	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RI02_05950	COG1309	transcriptional regulator
RI02_05960	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RI02_05965	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RI02_05970	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RI02_05975	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RI02_05995	COG4195	phage-related replication protein
RI02_06000	COG2856	Zn peptidase
RI02_06005	COG3409	Peptidoglycan-binding domain 1 protein
RI02_06005	COG5632	N-Acetylmuramoyl-L-alanine amidase
RI02_06025	COG0306	phosphate transporter
RI02_06030	COG1392	Phosphate transport regulator
RI02_06040	COG0405	Gamma-glutamyltransferase
RI02_06045	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
RI02_06055	COG4208	sulfate ABC transporter
RI02_06060	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
RI02_06070	COG3775	system Galactitol-specific IIC component
RI02_06085	COG1063	alcohol dehydrogenase
RI02_06090	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RI02_06095	COG0508	dehydrogenase complex catalyzes the overall conversion of
RI02_06095	COG0022	dehydrogenase e1 component
RI02_06100	COG0508	dehydrogenase complex catalyzes the overall conversion of
RI02_06105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RI02_06110	COG1028	Short-chain dehydrogenase reductase Sdr
RI02_06115	COG1028	Short-chain dehydrogenase reductase Sdr
RI02_06120	COG2390	Transcriptional regulator
RI02_06130	COG0531	amino acid
RI02_06135	COG0346	lactoylglutathione lyase activity
RI02_06145	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RI02_06150	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RI02_06155	COG2362	D-Aminopeptidase
RI02_06160	COG0601	transmembrane transport
RI02_06165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RI02_06170	COG0444	Belongs to the ABC transporter superfamily
RI02_06175	COG4166	transmembrane transport
RI02_06180	COG1619	proteins homologs of microcin C7 resistance protein MccF
RI02_06185	COG4948	Mandelate Racemase Muconate Lactonizing
RI02_06190	COG0791	NLP P60 protein
RI02_06195	COG4608	Belongs to the ABC transporter superfamily
RI02_06200	COG1834	amidinotransferase
RI02_06205	COG1607	acyl-coa hydrolase
RI02_06210	COG1695	Transcriptional regulator
RI02_06225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RI02_06235	COG2076	Multidrug Resistance protein
RI02_06240	COG2076	Multidrug Resistance protein
RI02_06250	COG0788	formyltetrahydrofolate deformylase activity
RI02_06255	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
RI02_06260	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
RI02_06265	COG0457	Tetratricopeptide repeat
RI02_06275	COG1764	response to oxidative stress
RI02_06280	COG1846	Transcriptional regulator
RI02_06285	COG1764	response to oxidative stress
RI02_06290	COG0590	tRNA wobble adenosine to inosine editing
RI02_06295	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
RI02_06300	COG1404	Belongs to the peptidase S8 family
RI02_06315	COG0745	RESPONSE REGULATOR receiver
RI02_06320	COG5002	protein histidine kinase activity
RI02_06320	COG3850	Histidine kinase
RI02_06325	COG3212	peptidase
RI02_06330	COG3212	peptidase
RI02_06340	COG2239	Acts as a magnesium transporter
RI02_06350	COG0583	DNA-binding transcription factor activity
RI02_06360	COG0789	Transcriptional regulator
RI02_06370	COG1846	Transcriptional regulator
RI02_06375	COG3300	MHYT domain
RI02_06375	COG5001	Diguanylate cyclase
RI02_06380	COG0586	Pfam SNARE associated Golgi protein
RI02_06385	COG0861	Integral membrane protein TerC family
RI02_06390	COG1191	sigma factor activity
RI02_06410	COG0501	Belongs to the peptidase M48B family
RI02_06415	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RI02_06420	COG2323	membrane
RI02_06430	COG3594	Acyltransferase
RI02_06435	COG5002	protein histidine kinase activity
RI02_06440	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RI02_06445	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
RI02_06450	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
RI02_06455	COG0436	Aminotransferase
RI02_06460	COG1850	ribulose-bisphosphate carboxylase activity
RI02_06465	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
RI02_06470	COG0235	Class ii aldolase
RI02_06475	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
RI02_06485	COG3852	Histidine kinase
RI02_06490	COG1846	Transcriptional regulator
RI02_06495	COG1360	Flagellar Motor Protein
RI02_06500	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
RI02_06505	COG0542	response to heat
RI02_06515	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
RI02_06520	COG0720	synthase
RI02_06525	COG0602	queuosine metabolic process
RI02_06530	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
RI02_06545	COG4873	Protein conserved in bacteria
RI02_06555	COG3773	Cell wall hydrolase
RI02_06560	COG2244	polysaccharide biosynthetic process
RI02_06565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RI02_06570	COG2217	Heavy metal translocating P-type atpase
RI02_06575	COG0006	proline dipeptidase activity
RI02_06580	COG1609	Transcriptional regulator
RI02_06585	COG3711	transcriptional antiterminator
RI02_06590	COG1263	PTS System
RI02_06590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RI02_06590	COG2190	(PTS) system
RI02_06595	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RI02_06600	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RI02_06610	COG1533	DNA photolyase activity
RI02_06615	COG0840	transmembrane signaling receptor activity
RI02_06625	COG2084	Dehydrogenase
RI02_06630	COG2340	Cysteine-rich secretory protein family
RI02_06635	COG0768	penicillin binding
RI02_06645	COG0436	Aminotransferase
RI02_06650	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
RI02_06655	COG1714	RDD family
RI02_06665	COG0835	chemotaxis
RI02_06665	COG0784	Response regulator, receiver
RI02_06675	COG2207	Transcriptional regulator
RI02_06675	COG1917	Cupin 2, conserved barrel domain protein
RI02_06680	COG0697	spore germination
RI02_06695	COG2814	Major facilitator Superfamily
RI02_06700	COG1376	ErfK ybiS ycfS ynhG family protein
RI02_06705	COG1408	metallophosphoesterase
RI02_06710	COG1028	Short-chain dehydrogenase reductase Sdr
RI02_06715	COG2200	EAL domain
RI02_06720	COG3546	catalase activity
RI02_06725	COG4703	Protein of unknown function (DUF1797)
RI02_06730	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
RI02_06740	COG0517	IMP dehydrogenase activity
RI02_06745	COG0583	DNA-binding transcription factor activity
RI02_06755	COG0716	FMN binding
RI02_06765	COG0716	FMN binding
RI02_06770	COG2171	N-acyltransferase activity
RI02_06775	COG1473	amidohydrolase
RI02_06785	COG0668	transmembrane transport
RI02_06790	COG0450	alkyl hydroperoxide reductase
RI02_06795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RI02_06810	COG0746	molybdenum cofactor guanylyltransferase activity
RI02_06815	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RI02_06820	COG0303	'Molybdopterin
RI02_06825	COG1763	Mo-molybdopterin cofactor biosynthetic process
RI02_06830	COG0314	molybdopterin synthase activity
RI02_06835	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
RI02_06850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RI02_06855	COG1136	(ABC) transporter
RI02_06860	COG0577	efflux transmembrane transporter activity
RI02_06865	COG1349	DNA-binding transcription factor activity
RI02_06870	COG1105	Belongs to the carbohydrate kinase PfkB family
RI02_06875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RI02_06875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RI02_06875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RI02_06880	COG0681	Belongs to the peptidase S26 family
RI02_06890	COG0488	(ABC) transporter
RI02_06905	COG2309	aminopeptidase activity
RI02_06910	COG1077	Cell shape determining protein MreB Mrl
RI02_06915	COG2002	toxin-antitoxin pair type II binding
RI02_06920	COG3852	Histidine kinase
RI02_06925	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
RI02_06925	COG2105	PFAM AIG2 family protein
RI02_06930	COG0569	domain protein
RI02_06935	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
RI02_06940	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
RI02_06945	COG5503	Protein of unknown function (DUF1447)
RI02_06950	COG0561	phosphatase activity
RI02_06955	COG0242	peptide deformylase activity
RI02_06970	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RI02_06975	COG0022	dehydrogenase e1 component
RI02_06980	COG0508	dehydrogenase complex catalyzes the overall conversion of
RI02_06985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RI02_06990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RI02_07000	COG1982	Orn Lys Arg decarboxylase major
RI02_07005	COG4476	Belongs to the UPF0223 family
RI02_07010	COG4493	Belongs to the UPF0637 family
RI02_07020	COG0483	inositol monophosphate 1-phosphatase activity
RI02_07035	COG1595	DNA-templated transcription, initiation
RI02_07055	COG1217	gtp-binding protein TYPA
RI02_07065	COG4896	Protein conserved in bacteria
RI02_07075	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
RI02_07080	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RI02_07085	COG2066	Belongs to the glutaminase family
RI02_07090	COG4838	Belongs to the UPF0358 family
RI02_07095	COG0772	Belongs to the SEDS family
RI02_07100	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
RI02_07105	COG0415	Belongs to the DNA photolyase family
RI02_07110	COG1612	heme a metabolic process
RI02_07115	COG0109	protoheme IX farnesyltransferase activity
RI02_07120	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
RI02_07120	COG2010	Cytochrome c
RI02_07125	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RI02_07130	COG1845	cytochrome c oxidase, subunit III
RI02_07135	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
RI02_07140	COG3336	cytochrome c oxidase
RI02_07150	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
RI02_07155	COG2340	Cysteine-rich secretory protein family
RI02_07175	COG3679	Belongs to the UPF0342 family
RI02_07180	COG4471	UPF0298 protein
RI02_07185	COG0742	ribosomal rna small subunit methyltransferase
RI02_07190	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
RI02_07195	COG3314	Sporulation integral membrane protein YlbJ
RI02_07200	COG1752	Esterase of the alpha-beta hydrolase superfamily
RI02_07205	COG3480	Lon protease (S16) C-terminal proteolytic domain
RI02_07215	COG1399	metal-binding, possibly nucleic acid-binding protein
RI02_07220	COG0333	Belongs to the bacterial ribosomal protein bL32 family
RI02_07230	COG0454	-acetyltransferase
RI02_07235	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RI02_07240	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
RI02_07245	COG2001	Belongs to the MraZ family
RI02_07250	COG0275	rRNA processing
RI02_07255	COG4839	cell division protein FtsL
RI02_07260	COG0768	penicillin binding
RI02_07270	COG0768	penicillin binding
RI02_07275	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RI02_07280	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RI02_07285	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RI02_07290	COG0772	Belongs to the SEDS family
RI02_07295	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RI02_07300	COG0812	UDP-N-acetylmuramate dehydrogenase activity
RI02_07305	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RI02_07310	COG3879	Bacterial protein of unknown function (DUF881)
RI02_07315	COG3879	Bacterial protein of unknown function (DUF881)
RI02_07320	COG3856	small basic protein
RI02_07325	COG0849	cell division
RI02_07330	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RI02_07335	COG4412	M6 family metalloprotease domain protein
RI02_07335	COG1404	Belongs to the peptidase S8 family
RI02_07345	COG1191	sigma factor activity
RI02_07350	COG1191	sigma factor activity
RI02_07355	COG2390	Transcriptional regulator
RI02_07370	COG3730	PTS system glucitol sorbitol-specific
RI02_07375	COG3732	PTS system glucitol sorbitol-specific
RI02_07385	COG1119	ATPase activity
RI02_07390	COG1873	PFAM PRC-barrel domain
RI02_07395	COG1496	oxidoreductase activity
RI02_07400	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RI02_07405	COG1799	cell septum assembly
RI02_07410	COG0762	integral membrane protein
RI02_07415	COG2302	S4 RNA-binding domain
RI02_07420	COG3599	regulation of cell shape
RI02_07425	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
RI02_07430	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
RI02_07435	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
RI02_07440	COG0564	pseudouridine synthase activity
RI02_07445	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
RI02_07450	COG2233	PERMEase
RI02_07455	COG0540	Belongs to the ATCase OTCase family
RI02_07460	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RI02_07465	COG0505	Belongs to the CarA family
RI02_07470	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RI02_07475	COG0543	2 iron, 2 sulfur cluster binding
RI02_07480	COG0167	dihydroorotate dehydrogenase activity
RI02_07485	COG0284	orotidine-5'-phosphate decarboxylase activity
RI02_07490	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
RI02_07500	COG0175	sulfate reduction
RI02_07505	COG0306	phosphate transporter
RI02_07510	COG2046	Belongs to the sulfate adenylyltransferase family
RI02_07515	COG0529	Catalyzes the synthesis of activated sulfate
RI02_07520	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RI02_07525	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
RI02_07530	COG1648	precorrin-2 dehydrogenase activity
RI02_07540	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
RI02_07545	COG1561	YicC-like family, N-terminal region
RI02_07550	COG2052	Domain of unknown function (DUF370)
RI02_07555	COG0194	GDP metabolic process
RI02_07560	COG1758	RNA polymerase activity
RI02_07565	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RI02_07570	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RI02_07575	COG0242	peptide deformylase activity
RI02_07580	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
RI02_07585	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RI02_07585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RI02_07590	COG0820	rRNA (adenine-C2-)-methyltransferase activity
RI02_07595	COG0631	protein serine/threonine phosphatase activity
RI02_07600	COG0515	serine threonine protein kinase
RI02_07600	COG2815	serine threonine protein kinase
RI02_07605	COG1162	GTPase activity
RI02_07610	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RI02_07615	COG1564	THIamine pyrophosphokinase
RI02_07625	COG0227	Belongs to the bacterial ribosomal protein bL28 family
RI02_07630	COG1302	Protein conserved in bacteria
RI02_07635	COG1461	Dihydroxyacetone kinase
RI02_07640	COG1760	l-serine dehydratase
RI02_07645	COG1760	l-serine dehydratase
RI02_07650	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RI02_07655	COG1349	DNA-binding transcription factor activity
RI02_07660	COG0416	fatty acid biosynthetic process
RI02_07665	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
RI02_07670	COG1028	Short-chain dehydrogenase reductase Sdr
RI02_07675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RI02_07685	COG1196	nuclear chromosome segregation
RI02_07690	COG0552	protein localization to endoplasmic reticulum
RI02_07695	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
RI02_07700	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RI02_07705	COG0228	four-way junction DNA binding
RI02_07710	COG1837	Belongs to the UPF0109 family
RI02_07720	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
RI02_07725	COG0336	Belongs to the RNA methyltransferase TrmD family
RI02_07730	COG0335	large ribosomal subunit rRNA binding
RI02_07735	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
RI02_07740	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
RI02_07750	COG2257	FlhB HrpN YscU SpaS Family
RI02_07755	COG0045	succinate-CoA ligase (ADP-forming) activity
RI02_07760	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RI02_07765	COG0758	DNA mediated transformation
RI02_07770	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RI02_07775	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
RI02_07780	COG4974	Belongs to the 'phage' integrase family
RI02_07785	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
RI02_07790	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
RI02_07795	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
RI02_07800	COG1815	bacterial-type flagellum-dependent cell motility
RI02_07805	COG1558	bacterial-type flagellum-dependent cell motility
RI02_07810	COG1677	Flagellar hook-basal body complex protein FliE
RI02_07815	COG1766	The M ring may be actively involved in energy transduction
RI02_07820	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RI02_07825	COG1317	bacterial-type flagellum organization
RI02_07830	COG1157	protein secretion by the type III secretion system
RI02_07835	COG2882	bacterial-type flagellum organization
RI02_07840	COG3334	PFAM MgtE intracellular
RI02_07845	COG3144	bacterial-type flagellum assembly
RI02_07850	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
RI02_07855	COG4786	Flagellar basal body rod
RI02_07860	COG1582	Flagellar protein (FlbD)
RI02_07865	COG1580	Controls the rotational direction of flagella during chemotaxis
RI02_07870	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RI02_07875	COG1776	CheC inhibitor of MCP methylation
RI02_07875	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RI02_07880	COG2201	protein-glutamate methylesterase activity
RI02_07885	COG3190	flagellar
RI02_07890	COG1338	Plays a role in the flagellum-specific transport system
RI02_07895	COG1987	bacterial-type flagellum assembly
RI02_07900	COG1684	flagellar biosynthetic protein fliR
RI02_07905	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RI02_07910	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RI02_07915	COG1419	protein localization to endoplasmic reticulum
RI02_07920	COG0455	bacterial-type flagellum organization
RI02_07925	COG2201	protein-glutamate methylesterase activity
RI02_07930	COG2198	Histidine kinase
RI02_07930	COG0643	Histidine kinase
RI02_07935	COG0835	chemotaxis
RI02_07940	COG1776	CheC inhibitor of MCP methylation
RI02_07950	COG1191	sigma factor activity
RI02_07965	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
RI02_07970	COG0528	UMP kinase activity
RI02_07975	COG0233	cytoplasmic translational termination
RI02_07980	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
RI02_07985	COG4589	Belongs to the CDS family
RI02_07990	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
RI02_07995	COG0750	zinc metalloprotease
RI02_08000	COG0442	prolyl-tRNA aminoacylation
RI02_08005	COG2176	DNA-directed DNA polymerase activity
RI02_08020	COG3693	PFAM glycoside hydrolase, family 10
RI02_08035	COG0779	Required for maturation of 30S ribosomal subunits
RI02_08040	COG0195	Participates in both transcription termination and antitermination
RI02_08045	COG2740	Nucleic-acid-binding protein implicated in transcription termination
RI02_08050	COG1358	cellular component organization or biogenesis
RI02_08055	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
RI02_08060	COG1550	Protein conserved in bacteria
RI02_08065	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
RI02_08070	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
RI02_08075	COG0196	riboflavin kinase activity
RI02_08080	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
RI02_08085	COG1185	polyribonucleotide nucleotidyltransferase activity
RI02_08090	COG0726	polysaccharide deacetylase
RI02_08095	COG0612	Peptidase, M16
RI02_08105	COG1873	PFAM PRC-barrel domain
RI02_08110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RI02_08115	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RI02_08120	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RI02_08125	COG0527	aspartate kinase activity
RI02_08135	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
RI02_08140	COG0740	serine-type endopeptidase activity
RI02_08150	COG1674	ftsk spoiiie
RI02_08150	COG4980	gas vesicle protein
RI02_08155	COG2188	Transcriptional regulator
RI02_08160	COG2814	Major facilitator Superfamily
RI02_08165	COG1033	growth of symbiont in host cell
RI02_08165	COG2409	Drug exporters of the RND superfamily
RI02_08170	COG0612	Peptidase, M16
RI02_08175	COG0612	Peptidase, M16
RI02_08185	COG2409	Drug exporters of the RND superfamily
RI02_08185	COG1033	growth of symbiont in host cell
RI02_08190	COG0300	oxidoreductase activity
RI02_08205	COG1426	Protein conserved in bacteria
RI02_08210	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
RI02_08215	COG1546	Belongs to the CinA family
RI02_08215	COG1058	Belongs to the CinA family
RI02_08220	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
RI02_08225	COG1418	mRNA catabolic process
RI02_08230	COG1692	metallophosphoesterase
RI02_08235	COG2359	stage V sporulation protein S
RI02_08240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RI02_08245	COG1063	alcohol dehydrogenase
RI02_08250	COG0156	8-amino-7-oxononanoate synthase activity
RI02_08255	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RI02_08260	COG4550	Control of competence regulator ComK, YlbF/YmcA
RI02_08270	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
RI02_08275	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
RI02_08295	COG1329	Transcriptional regulator
RI02_08300	COG4195	phage-related replication protein
RI02_08305	COG0457	Tetratricopeptide repeat
RI02_08310	COG1404	Belongs to the peptidase S8 family
RI02_08315	COG4195	phage-related replication protein
RI02_08320	COG1764	response to oxidative stress
RI02_08350	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
RI02_08355	COG1923	regulation of RNA biosynthetic process
RI02_08370	COG1780	Probably involved in ribonucleotide reductase function
RI02_08375	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RI02_08380	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RI02_08385	COG4112	unkown
RI02_08395	COG0464	growth
RI02_08400	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RI02_08405	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
RI02_08410	COG0789	Transcriptional regulator
RI02_08415	COG0174	glutamine synthetase
RI02_08435	COG0457	Tetratricopeptide repeat
RI02_08455	COG5444	nuclease activity
RI02_08480	COG5646	InterPro IPR014922
RI02_08500	COG0457	Tetratricopeptide repeat
RI02_08510	COG3619	membrane
RI02_08515	COG1793	dna ligase
RI02_08515	COG3285	dna ligase
RI02_08520	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
RI02_08525	COG4876	unkown
RI02_08535	COG1959	2 iron, 2 sulfur cluster binding
RI02_08540	COG0702	epimerase
RI02_08550	COG0247	lactate metabolic process
RI02_08555	COG1139	Iron-sulfur cluster binding protein
RI02_08560	COG1556	Lactate utilization protein
RI02_08575	COG2323	membrane
RI02_08580	COG1309	transcriptional regulator
RI02_08585	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RI02_08585	COG2124	cytochrome p450
RI02_08590	COG3591	Belongs to the peptidase S1B family
RI02_08595	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RI02_08600	COG3209	COG3209 Rhs family protein
RI02_08605	COG1366	Belongs to the anti-sigma-factor antagonist family
RI02_08620	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RI02_08625	COG1388	LysM domain
RI02_08630	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RI02_08635	COG4224	UPF0291 protein
RI02_08640	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
RI02_08650	COG3763	UPF0154 protein
RI02_08660	COG0785	Cytochrome C biogenesis protein
RI02_08665	COG4846	Membrane protein involved in cytochrome C biogenesis
RI02_08675	COG0071	Belongs to the small heat shock protein (HSP20) family
RI02_08690	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
RI02_08695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RI02_08715	COG0824	Thioesterase
RI02_08725	COG4841	protein insertion into membrane
RI02_08730	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
RI02_08735	COG1832	CoA-binding protein
RI02_08740	COG0187	DNA topoisomerase II activity
RI02_08745	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RI02_08755	COG0738	Major facilitator superfamily
RI02_08760	COG0473	3-isopropylmalate dehydrogenase activity
RI02_08770	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RI02_08775	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
RI02_08780	COG0640	Transcriptional regulator
RI02_08790	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
RI02_08805	COG1309	transcriptional regulator
RI02_08810	COG2249	NAD(P)H dehydrogenase (quinone) activity
RI02_08815	COG1733	regulation of RNA biosynthetic process
RI02_08820	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RI02_08825	COG0251	oxidation-reduction process
RI02_08865	COG0657	acetylesterase activity
RI02_08875	COG2723	6-phospho-beta-galactosidase activity
RI02_08880	COG1263	PTS System
RI02_08880	COG2190	(PTS) system
RI02_08880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RI02_08895	COG2205	protein histidine kinase activity
RI02_08900	COG0745	RESPONSE REGULATOR receiver
RI02_08910	COG3507	Belongs to the glycosyl hydrolase 43 family
RI02_08915	COG1012	belongs to the aldehyde dehydrogenase family
RI02_08920	COG1486	melibiose metabolic process
RI02_08925	COG0395	ABC-type sugar transport system, permease component
RI02_08930	COG1175	transmembrane transport
RI02_08935	COG1653	transport
RI02_08940	COG1609	Transcriptional regulator
RI02_08945	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RI02_08960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RI02_08995	COG5444	nuclease activity
RI02_09000	COG1846	Transcriptional regulator
RI02_09005	COG2814	Major facilitator Superfamily
RI02_09015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RI02_09015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RI02_09015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RI02_09020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RI02_09020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RI02_09020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RI02_09025	COG1105	Belongs to the carbohydrate kinase PfkB family
RI02_09035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RI02_09055	COG1012	belongs to the aldehyde dehydrogenase family
RI02_09060	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RI02_09065	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RI02_09070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RI02_09075	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RI02_09080	COG1024	Enoyl-CoA hydratase
RI02_09085	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RI02_09090	COG0511	ligase activity, forming carbon-carbon bonds
RI02_09095	COG0439	Biotin carboxylase
RI02_09100	COG0318	PFAM AMP-dependent synthetase and ligase
RI02_09105	COG1960	acyl-CoA dehydrogenase activity
RI02_09110	COG1649	PFAM Uncharacterised BCR, COG1649
RI02_09115	COG2365	Tyrosine phosphatase family
RI02_09120	COG1349	DNA-binding transcription factor activity
RI02_09125	COG1942	4-Oxalocrotonate Tautomerase
RI02_09135	COG3835	regulator
RI02_09140	COG0277	FAD linked oxidase domain protein
RI02_09145	COG0247	lactate metabolic process
RI02_09165	COG0166	Belongs to the GPI family
RI02_09170	COG2246	polysaccharide biosynthetic process
RI02_09175	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RI02_09180	COG0586	Pfam SNARE associated Golgi protein
RI02_09185	COG1587	Uroporphyrinogen-III synthase
RI02_09195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RI02_09210	COG0534	Mate efflux family protein
RI02_09215	COG2027	D-alanyl-D-alanine carboxypeptidase
RI02_09220	COG4677	pectinesterase activity
RI02_09225	COG2323	membrane
RI02_09230	COG2146	nitrite reductase [NAD(P)H] activity
RI02_09235	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RI02_09240	COG0243	molybdopterin cofactor binding
RI02_09245	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RI02_09250	COG2223	nitrite transmembrane transporter activity
RI02_09255	COG0493	'glutamate synthase
RI02_09260	COG0069	glutamate synthase activity
RI02_09260	COG0067	glutamate synthase
RI02_09260	COG0070	glutamate synthase
RI02_09265	COG0583	DNA-binding transcription factor activity
RI02_09275	COG1132	(ABC) transporter
RI02_09280	COG0789	Transcriptional regulator
RI02_09280	COG4978	Transcriptional regulator
RI02_09285	COG0454	-acetyltransferase
RI02_09290	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
RI02_09295	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
RI02_09300	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RI02_09310	COG0243	molybdopterin cofactor binding
RI02_09320	COG1070	Carbohydrate kinase
RI02_09325	COG2115	Belongs to the xylose isomerase family
RI02_09330	COG1940	carbohydrate kinase activity
RI02_09340	COG2211	Major facilitator Superfamily
RI02_09345	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RI02_09350	COG1994	Peptidase M50
RI02_09370	COG1309	transcriptional regulator
RI02_09375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RI02_09380	COG3708	Transcriptional regulator
RI02_09385	COG2378	regulation of single-species biofilm formation
RI02_09395	COG0640	Transcriptional regulator
RI02_09400	COG0531	amino acid
RI02_09405	COG0741	lytic transglycosylase activity
RI02_09410	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
RI02_09415	COG2079	MmgE PrpD family protein
RI02_09420	COG0372	Belongs to the citrate synthase family
RI02_09425	COG2322	membrane
RI02_09435	COG1388	LysM domain
RI02_09435	COG3584	3D domain protein
RI02_09440	COG0514	ATP-dependent DNA helicase (RecQ)
RI02_09450	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
RI02_09475	COG1012	belongs to the aldehyde dehydrogenase family
RI02_09480	COG1657	PFAM Prenyltransferase squalene oxidase
RI02_09485	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RI02_09490	COG0385	Bile acid
RI02_09495	COG0508	dehydrogenase complex catalyzes the overall conversion of
RI02_09500	COG0567	Dehydrogenase, E1 component
RI02_09505	COG4548	von Willebrand factor, type A
RI02_09510	COG0714	Associated with various cellular activities
RI02_09515	COG2032	superoxide dismutase activity
RI02_09520	COG1388	LysM domain
RI02_09520	COG0791	NLP P60 protein
RI02_09525	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
RI02_09530	COG0534	Mate efflux family protein
RI02_09535	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RI02_09540	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RI02_09550	COG2962	Rard protein
RI02_09565	COG1733	regulation of RNA biosynthetic process
RI02_09570	COG0778	Nitroreductase
RI02_09580	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RI02_09585	COG0793	Belongs to the peptidase S41A family
RI02_09585	COG3409	Peptidoglycan-binding domain 1 protein
RI02_09590	COG2226	methyltransferase
RI02_09605	COG1876	peptidase activity
RI02_09610	COG0813	purine-nucleoside phosphorylase activity
RI02_09620	COG0671	phosphoesterase, PA-phosphatase related
RI02_09635	COG4479	Belongs to the UPF0346 family
RI02_09645	COG1509	lysine 2,3-aminomutase activity
RI02_09650	COG3829	transcription factor binding
RI02_09655	COG0463	Glycosyl transferase, family 2
RI02_09670	COG4641	Protein conserved in bacteria
RI02_09680	COG1086	Polysaccharide biosynthesis protein
RI02_09685	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RI02_09690	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RI02_09695	COG1846	Transcriptional regulator
RI02_09720	COG4698	Protein conserved in bacteria
RI02_09725	COG2755	lipolytic protein G-D-S-L family
RI02_09730	COG1999	signal sequence binding
RI02_09745	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RI02_09750	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
RI02_09755	COG1272	protein, Hemolysin III
RI02_09760	COG0204	Acyl-transferase
RI02_09765	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
RI02_09770	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
RI02_09775	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
RI02_09785	COG2136	Putative SAM-dependent methyltransferase
RI02_09785	COG2521	methyltransferase
RI02_09795	COG0129	dihydroxy-acid dehydratase activity
RI02_09800	COG1413	lyase activity
RI02_09805	COG1418	mRNA catabolic process
RI02_09810	COG0386	Belongs to the glutathione peroxidase family
RI02_09815	COG2759	Belongs to the formate--tetrahydrofolate ligase family
RI02_09820	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
RI02_09825	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RI02_09835	COG1278	Cold shock
RI02_09850	COG0328	RNA-DNA hybrid ribonuclease activity
RI02_09855	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
RI02_09860	COG0328	RNA-DNA hybrid ribonuclease activity
RI02_09870	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RI02_09880	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
RI02_09890	COG1755	Isoprenylcysteine carboxyl methyltransferase
RI02_09895	COG3424	synthase
RI02_09900	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
RI02_09900	COG0456	acetyltransferase
RI02_09905	COG0726	polysaccharide deacetylase
RI02_09910	COG2233	PERMEase
RI02_09915	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RI02_09920	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
RI02_09925	COG1199	ATP-dependent helicase activity
RI02_09935	COG0116	Belongs to the methyltransferase superfamily
RI02_09945	COG3599	regulation of cell shape
RI02_09950	COG4474	Belongs to the UPF0398 family
RI02_09960	COG3359	exonuclease
RI02_09965	COG1205	dead DEAH box helicase
RI02_09965	COG1111	helicase
RI02_09970	COG1902	pentaerythritol trinitrate reductase activity
RI02_09975	COG2190	(PTS) system
RI02_09980	COG0071	Belongs to the small heat shock protein (HSP20) family
RI02_10010	COG3331	DNA recombination
RI02_10015	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RI02_10015	COG4499	WXG100 protein secretion system (Wss), protein YukC
RI02_10025	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RI02_10030	COG3935	DnaD domain protein
RI02_10035	COG0017	Asparaginyl-tRNA synthetase
RI02_10040	COG5353	protein conserved in bacteria
RI02_10050	COG1199	ATP-dependent helicase activity
RI02_10050	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RI02_10055	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
RI02_10060	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
RI02_10065	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
RI02_10075	COG0617	tRNA 3'-terminal CCA addition
RI02_10080	COG0438	transferase activity, transferring glycosyl groups
RI02_10085	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RI02_10090	COG1803	Methylglyoxal synthase
RI02_10095	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
RI02_10100	COG1694	Mazg nucleotide pyrophosphohydrolase
RI02_10105	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RI02_10115	COG4347	Protein of unknown function (DUF1405)
RI02_10120	COG2010	Cytochrome c
RI02_10120	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
RI02_10125	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
RI02_10130	COG0723	plastoquinol--plastocyanin reductase activity
RI02_10140	COG5582	Belongs to the UPF0302 family
RI02_10145	COG0457	Tetratricopeptide repeat
RI02_10150	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
RI02_10155	COG0287	Prephenate dehydrogenase
RI02_10160	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RI02_10165	COG0159	tryptophan synthase activity
RI02_10170	COG0133	tryptophan synthase activity
RI02_10175	COG0135	phosphoribosylanthranilate isomerase activity
RI02_10180	COG0134	indole-3-glycerol-phosphate synthase activity
RI02_10185	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RI02_10195	COG4401	Chorismate mutase type I
RI02_10200	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
RI02_10205	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
RI02_10210	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
RI02_10215	COG0105	UTP biosynthetic process
RI02_10220	COG0142	geranyltranstransferase activity
RI02_10225	COG2226	methyltransferase
RI02_10230	COG0142	geranyltranstransferase activity
RI02_10240	COG0302	gtp cyclohydrolase
RI02_10245	COG0776	regulation of translation
RI02_10250	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
RI02_10265	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
RI02_10270	COG1160	GTP binding
RI02_10300	COG1304	FMN binding
RI02_10305	COG0539	negative regulation of cytoplasmic translation
RI02_10310	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
RI02_10320	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
RI02_10325	COG2959	enzyme of heme biosynthesis
RI02_10330	COG3773	Cell wall hydrolase
RI02_10330	COG3409	Peptidoglycan-binding domain 1 protein
RI02_10335	COG2339	peptidase activity
RI02_10340	COG0492	ferredoxin-NADP+ reductase activity
RI02_10345	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RI02_10350	COG4862	establishment of competence for transformation
RI02_10355	COG1408	metallophosphoesterase
RI02_10365	COG1388	LysM domain
RI02_10370	COG1266	CAAX protease self-immunity
RI02_10375	COG0514	ATP-dependent DNA helicase (RecQ)
RI02_10380	COG4955	Helix-turn-helix domain
RI02_10385	COG1141	Ferredoxin
RI02_10390	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
RI02_10395	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RI02_10410	COG1595	DNA-templated transcription, initiation
RI02_10415	COG5002	protein histidine kinase activity
RI02_10420	COG0745	RESPONSE REGULATOR receiver
RI02_10425	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RI02_10430	COG1333	cytochrome c biogenesis protein
RI02_10435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RI02_10440	COG1187	pseudouridine synthase activity
RI02_10445	COG0700	Nucleoside recognition
RI02_10450	COG2715	membrane protein required for spore maturation
RI02_10455	COG1686	Belongs to the peptidase S11 family
RI02_10465	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
RI02_10470	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
RI02_10480	COG1547	Domain of unknown function (DUF309)
RI02_10490	COG0456	acetyltransferase
RI02_10495	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
RI02_10500	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RI02_10500	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RI02_10505	COG0307	riboflavin synthase, alpha
RI02_10530	COG2814	Major facilitator Superfamily
RI02_10535	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
RI02_10540	COG4086	secreted protein
RI02_10545	COG0019	diaminopimelate decarboxylase activity
RI02_10550	COG0697	spore germination
RI02_10565	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RI02_10585	COG1191	sigma factor activity
RI02_10590	COG2172	sigma factor antagonist activity
RI02_10600	COG1686	Belongs to the peptidase S11 family
RI02_10605	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
RI02_10610	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
RI02_10615	COG4974	Belongs to the 'phage' integrase family
RI02_10625	COG0735	belongs to the Fur family
RI02_10630	COG1300	Membrane
RI02_10635	COG1404	Belongs to the peptidase S8 family
RI02_10650	COG2153	protein acetylation
RI02_10655	COG1379	DNA repair
RI02_10660	COG0494	nUDIX hydrolase
RI02_10665	COG0667	Aldo Keto reductase
RI02_10675	COG1073	alpha beta
RI02_10680	COG0457	Tetratricopeptide repeat
RI02_10690	COG4918	Iron-sulphur cluster biosynthesis
RI02_10695	COG4305	rare lipoprotein A
RI02_10700	COG0456	acetyltransferase
RI02_10700	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
RI02_10705	COG0456	acetyltransferase
RI02_10715	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RI02_10725	COG2211	Major facilitator Superfamily
RI02_10730	COG1072	(Pantothenic acid kinase))
RI02_10735	COG0446	pyridine nucleotide-disulphide oxidoreductase
RI02_10745	COG0300	oxidoreductase activity
RI02_10750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RI02_10755	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RI02_10770	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RI02_10775	COG4187	Peptidase family M20/M25/M40
RI02_10780	COG1902	pentaerythritol trinitrate reductase activity
RI02_10785	COG0596	Alpha beta hydrolase
RI02_10790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RI02_10800	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
RI02_10805	COG2188	Transcriptional regulator
RI02_10810	COG2723	6-phospho-beta-galactosidase activity
RI02_10815	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RI02_10820	COG1447	Phosphotransferase system cellobiose-specific component IIA
RI02_10825	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RI02_10835	COG1028	Short-chain dehydrogenase reductase Sdr
RI02_10845	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
RI02_10850	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RI02_10860	COG0706	membrane insertase activity
RI02_10865	COG0835	chemotaxis
RI02_10870	COG2195	Cleaves the N-terminal amino acid of tripeptides
RI02_10875	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RI02_10880	COG0346	lactoylglutathione lyase activity
RI02_10885	COG1376	ErfK ybiS ycfS ynhG family protein
RI02_10890	COG4129	membrane
RI02_10895	COG1126	abc transporter atp-binding protein
RI02_10900	COG0765	amino acid transport
RI02_10905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RI02_10915	COG1597	lipid kinase activity
RI02_10925	COG0508	dehydrogenase complex catalyzes the overall conversion of
RI02_10930	COG0022	dehydrogenase e1 component
RI02_10935	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RI02_10940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RI02_10945	COG3426	butyrate kinase activity
RI02_10950	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RI02_10955	COG0280	phosphate acetyltransferase
RI02_10960	COG3829	transcription factor binding
RI02_10960	COG3290	protein histidine kinase activity
RI02_10970	COG0584	glycerophosphoryl diester phosphodiesterase
RI02_10975	COG0457	Tetratricopeptide repeat
RI02_10980	COG0745	RESPONSE REGULATOR receiver
RI02_10985	COG0750	zinc metalloprotease
RI02_10990	COG0497	DNA recombination
RI02_10995	COG1438	arginine binding
RI02_11000	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
RI02_11005	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
RI02_11010	COG0142	geranyltranstransferase activity
RI02_11015	COG1722	exodeoxyribonuclease VII activity
RI02_11020	COG1570	exodeoxyribonuclease VII activity
RI02_11025	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
RI02_11030	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RI02_11035	COG1302	Protein conserved in bacteria
RI02_11040	COG0439	Biotin carboxylase
RI02_11045	COG0511	ligase activity, forming carbon-carbon bonds
RI02_11085	COG3854	ATPases associated with a variety of cellular activities
RI02_11095	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
RI02_11100	COG0006	proline dipeptidase activity
RI02_11105	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
RI02_11115	COG3872	metal-dependent enzyme
RI02_11125	COG1752	Esterase of the alpha-beta hydrolase superfamily
RI02_11130	COG1321	iron dependent repressor
RI02_11135	COG0095	Lipoate-protein ligase
RI02_11140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RI02_11145	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RI02_11150	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RI02_11155	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RI02_11160	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RI02_11185	COG0681	Belongs to the peptidase S26 family
RI02_11220	COG4970	Tfp pilus assembly protein FimT
RI02_11225	COG4537	Required for transformation and DNA binding
RI02_11230	COG1459	type II secretion system
RI02_11235	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
RI02_11240	COG1366	Belongs to the anti-sigma-factor antagonist family
RI02_11250	COG1393	Belongs to the ArsC family
RI02_11260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RI02_11270	COG0011	TIGRFAM Protein of
RI02_11275	COG2814	Major facilitator Superfamily
RI02_11285	COG2866	Carboxypeptidase
RI02_11290	COG1368	sulfuric ester hydrolase activity
RI02_11295	COG1940	carbohydrate kinase activity
RI02_11300	COG4483	Protein conserved in bacteria
RI02_11305	COG0705	Rhomboid family
RI02_11305	COG0457	Tetratricopeptide repeat
RI02_11315	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RI02_11320	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RI02_11335	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RI02_11340	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RI02_11345	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RI02_11350	COG0581	inorganic phosphate transmembrane transporter activity
RI02_11355	COG0573	inorganic phosphate transmembrane transporter activity
RI02_11360	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
RI02_11365	COG0768	penicillin binding
RI02_11370	COG0477	Major facilitator Superfamily
RI02_11375	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RI02_11380	COG2839	Protein conserved in bacteria
RI02_11385	COG5521	maltodextrose utilization protein MalA
RI02_11390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RI02_11395	COG1388	LysM domain
RI02_11400	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
RI02_11405	COG4709	membrane
RI02_11410	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
RI02_11415	COG1940	carbohydrate kinase activity
RI02_11420	COG0735	belongs to the Fur family
RI02_11425	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RI02_11430	COG1121	(ABC) transporter
RI02_11435	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RI02_11450	COG0513	Belongs to the DEAD box helicase family
RI02_11460	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
RI02_11465	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
RI02_11470	COG2384	SAM-dependent methyltransferase
RI02_11475	COG2010	Cytochrome c
RI02_11480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RI02_11485	COG0358	DNA primase activity
RI02_11490	COG1671	Belongs to the UPF0178 family
RI02_11495	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
RI02_11500	COG0517	IMP dehydrogenase activity
RI02_11505	COG0751	glycine-tRNA ligase activity
RI02_11510	COG0752	glycyl-tRNA synthetase alpha subunit
RI02_11515	COG1381	Involved in DNA repair and RecF pathway recombination
RI02_11525	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
RI02_11530	COG0295	cytidine deaminase activity
RI02_11535	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
RI02_11540	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
RI02_11545	COG1480	7TM receptor with intracellular HD hydrolase
RI02_11550	COG1702	phosphate starvation-inducible protein PhoH
RI02_11555	COG0561	phosphatase activity
RI02_11570	COG4864	UPF0365 protein
RI02_11575	COG1030	water channel activity
RI02_11580	COG1610	YqeY-like protein
RI02_11590	COG1283	sodium-dependent phosphate transmembrane transporter activity
RI02_11595	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RI02_11600	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RI02_11605	COG2264	protein methyltransferase activity
RI02_11610	COG0484	heat shock protein binding
RI02_11615	COG0443	Heat shock 70 kDa protein
RI02_11620	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
RI02_11625	COG1420	regulation of RNA biosynthetic process
RI02_11630	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RI02_11635	COG0481	GTPase activity
RI02_11645	COG0860	N-Acetylmuramoyl-L-alanine amidase
RI02_11650	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
RI02_11655	COG0268	Binds directly to 16S ribosomal RNA
RI02_11660	COG1466	dna polymerase III delta subunit
RI02_11670	COG0658	competence protein
RI02_11670	COG2333	competence protein COMEC
RI02_11675	COG2131	deaminase
RI02_11680	COG1555	photosystem II stabilization
RI02_11680	COG1596	polysaccharide export
RI02_11685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RI02_11690	COG2226	methyltransferase
RI02_11695	COG0799	negative regulation of ribosome biogenesis
RI02_11700	COG1713	HD superfamily hydrolase involved in NAD metabolism
RI02_11705	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
RI02_11710	COG1534	Rna-binding protein
RI02_11715	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RI02_11720	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
RI02_11725	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
RI02_11735	COG2755	lipolytic protein G-D-S-L family
RI02_11745	COG0457	Tetratricopeptide repeat
RI02_11775	COG0726	polysaccharide deacetylase
RI02_11810	COG1131	(ABC) transporter
RI02_11840	COG2160	L-arabinose isomerase activity
RI02_11855	COG1609	Transcriptional regulator
RI02_11865	COG1846	Transcriptional regulator
RI02_11875	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
RI02_11880	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
RI02_11885	COG1733	regulation of RNA biosynthetic process
RI02_11890	COG0657	acetylesterase activity
RI02_11955	COG2602	Beta-lactamase
RI02_11960	COG1960	acyl-CoA dehydrogenase activity
RI02_11965	COG1126	abc transporter atp-binding protein
RI02_11970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RI02_11975	COG0765	amino acid transport
RI02_11985	COG3546	catalase activity
RI02_11990	COG1063	alcohol dehydrogenase
RI02_12000	COG1028	Short-chain dehydrogenase reductase Sdr
RI02_12010	COG1115	amino acid carrier protein
RI02_12015	COG0583	DNA-binding transcription factor activity
RI02_12020	COG0842	Transport permease protein
RI02_12025	COG1511	domain protein
RI02_12025	COG0842	Transport permease protein
RI02_12030	COG1131	(ABC) transporter
RI02_12035	COG1063	alcohol dehydrogenase
RI02_12040	COG2226	methyltransferase
RI02_12060	COG0626	cystathionine gamma-synthase activity
RI02_12065	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RI02_12070	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
RI02_12075	COG2226	methyltransferase
RI02_12090	COG0768	penicillin binding
RI02_12095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RI02_12100	COG0572	uridine kinase
RI02_12105	COG0826	peptidase U32
RI02_12110	COG0826	peptidase U32
RI02_12115	COG4122	O-methyltransferase activity
RI02_12120	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RI02_12125	COG0183	Belongs to the thiolase family
RI02_12130	COG0318	PFAM AMP-dependent synthetase and ligase
RI02_12135	COG1268	BioY protein
RI02_12140	COG3906	Belongs to the UPF0473 family
RI02_12145	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
RI02_12150	COG4472	Bacterial protein of unknown function (DUF965)
RI02_12155	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
RI02_12160	COG0628	permease
RI02_12165	COG1126	abc transporter atp-binding protein
RI02_12170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RI02_12175	COG0765	amino acid transport
RI02_12180	COG0765	amino acid transport
RI02_12195	COG3881	PFAM PRC-barrel domain
RI02_12200	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RI02_12205	COG0457	Tetratricopeptide repeat
RI02_12210	COG0482	sulfurtransferase activity
RI02_12215	COG1104	cysteine desulfurase activity
RI02_12220	COG1959	2 iron, 2 sulfur cluster binding
RI02_12225	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RI02_12230	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
RI02_12245	COG0124	histidyl-tRNA synthetase
RI02_12250	COG4991	sh3 domain protein
RI02_12250	COG0860	N-Acetylmuramoyl-L-alanine amidase
RI02_12250	COG3103	Sh3 type 3 domain protein
RI02_12255	COG1490	D-aminoacyl-tRNA deacylase activity
RI02_12260	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RI02_12265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RI02_12270	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
RI02_12270	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RI02_12275	COG5416	Lipopolysaccharide assembly protein A domain
RI02_12280	COG0490	domain, Protein
RI02_12285	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RI02_12285	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RI02_12295	COG2244	polysaccharide biosynthetic process
RI02_12300	COG2323	membrane
RI02_12310	COG1862	Preprotein translocase
RI02_12315	COG0343	queuine tRNA-ribosyltransferase activity
RI02_12320	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
RI02_12330	COG2255	four-way junction helicase activity
RI02_12335	COG0632	four-way junction helicase activity
RI02_12345	COG2112	serine threonine protein kinase
RI02_12355	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
RI02_12370	COG1388	LysM domain
RI02_12375	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
RI02_12380	COG0157	Belongs to the NadC ModD family
RI02_12385	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
RI02_12390	COG1104	cysteine desulfurase activity
RI02_12395	COG1827	regulation of RNA biosynthetic process
RI02_12400	COG0077	Prephenate dehydratase
RI02_12405	COG4492	Belongs to the UPF0735 family
RI02_12410	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
RI02_12415	COG3290	protein histidine kinase activity
RI02_12420	COG0211	Belongs to the bacterial ribosomal protein bL27 family
RI02_12425	COG2868	ribosomal protein
RI02_12430	COG0261	This protein binds to 23S rRNA in the presence of protein L20
RI02_12435	COG1994	Peptidase M50
RI02_12440	COG0739	heme binding
RI02_12445	COG2894	cell division
RI02_12450	COG0850	regulation of cytokinetic process
RI02_12455	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
RI02_12465	COG1077	Cell shape determining protein MreB Mrl
RI02_12470	COG2003	Belongs to the UPF0758 family
RI02_12475	COG0424	maF-like protein
RI02_12485	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
RI02_12490	COG0285	dihydrofolate synthase activity
RI02_12495	COG0525	valine-tRNA ligase activity
RI02_12505	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RI02_12510	COG1388	LysM domain
RI02_12515	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
RI02_12520	COG0113	porphobilinogen synthase activity
RI02_12525	COG1587	Uroporphyrinogen-III synthase
RI02_12530	COG0181	hydroxymethylbilane synthase activity
RI02_12535	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RI02_12540	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
RI02_12560	COG0218	Necessary for normal cell division and for the maintenance of normal septation
RI02_12565	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RI02_12570	COG0470	DNA polymerase III
RI02_12570	COG1067	ATP-dependent peptidase activity
RI02_12575	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
RI02_12580	COG0544	peptidyl-prolyl cis-trans isomerase activity
RI02_12585	COG1477	protein flavinylation
RI02_12585	COG0457	Tetratricopeptide repeat
RI02_12590	COG0066	3-isopropylmalate dehydratase activity
RI02_12595	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
RI02_12600	COG0473	3-isopropylmalate dehydrogenase activity
RI02_12605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RI02_12610	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
RI02_12615	COG0440	acetolactate synthase activity
RI02_12620	COG0028	Belongs to the TPP enzyme family
RI02_12625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RI02_12630	COG2706	6-phosphogluconolactonase activity
RI02_12635	COG3339	Conserved Protein
RI02_12640	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
RI02_12645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RI02_12650	COG1696	Membrane protein involved in D-alanine export
RI02_12655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RI02_12690	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
RI02_12695	COG5444	nuclease activity
RI02_12710	COG0622	Phosphoesterase
RI02_12715	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
RI02_12720	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
RI02_12725	COG5401	PFAM Sporulation and spore germination
RI02_12730	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
RI02_12735	COG1846	Transcriptional regulator
RI02_12740	COG2197	response regulator
RI02_12765	COG3409	Peptidoglycan-binding domain 1 protein
RI02_12765	COG5632	N-Acetylmuramoyl-L-alanine amidase
RI02_12770	COG4824	toxin secretion phage lysis holin
RI02_12800	COG1705	Flagellar rod assembly protein muramidase FlgJ
RI02_12880	COG4626	Terminase
RI02_12880	COG1802	Transcriptional regulator
RI02_12920	COG0582	viral genome integration into host DNA
RI02_12925	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
RI02_13005	COG2197	response regulator
RI02_13010	COG2851	Citrate transporter
RI02_13015	COG0583	DNA-binding transcription factor activity
RI02_13020	COG2828	Protein conserved in bacteria
RI02_13030	COG0824	Thioesterase
RI02_13035	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RI02_13040	COG1053	succinate dehydrogenase
RI02_13045	COG2009	succinate dehydrogenase
RI02_13050	COG1719	4-vinyl reductase, 4VR
RI02_13060	COG0527	aspartate kinase activity
RI02_13065	COG0322	excinuclease ABC activity
RI02_13070	COG3118	belongs to the thioredoxin family
RI02_13075	COG3534	alpha-L-arabinofuranosidase
RI02_13080	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
RI02_13085	COG2086	electron transfer activity
RI02_13090	COG1024	Enoyl-CoA hydratase
RI02_13095	COG1309	transcriptional regulator
RI02_13100	COG0318	PFAM AMP-dependent synthetase and ligase
RI02_13110	COG3766	membrane
RI02_13115	COG1193	negative regulation of DNA recombination
RI02_13120	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RI02_13120	COG1796	DNA polymerase
RI02_13125	COG1286	toxin biosynthetic process
RI02_13130	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
RI02_13135	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
RI02_13140	COG0072	phenylalanine-tRNA ligase activity
RI02_13140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RI02_13145	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
RI02_13150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RI02_13160	COG1966	Carbon starvation protein
RI02_13165	COG1363	Peptidase, m42
RI02_13175	COG3326	Membrane
RI02_13180	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
RI02_13185	COG0291	Belongs to the bacterial ribosomal protein bL35 family
RI02_13190	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
RI02_13200	COG1011	Hydrolase
RI02_13210	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RI02_13225	COG0398	Pfam SNARE associated Golgi protein
RI02_13230	COG1484	DNA-dependent DNA replication
RI02_13235	COG3611	Membrane attachment protein
RI02_13240	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
RI02_13250	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
RI02_13255	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RI02_13260	COG0237	dephospho-CoA kinase activity
RI02_13265	COG1971	Probably functions as a manganese efflux pump
RI02_13270	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RI02_13275	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RI02_13275	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RI02_13280	COG5002	protein histidine kinase activity
RI02_13285	COG0745	RESPONSE REGULATOR receiver
RI02_13290	COG0039	L-malate dehydrogenase activity
RI02_13295	COG0538	isocitrate dehydrogenase activity
RI02_13300	COG0372	Belongs to the citrate synthase family
RI02_13305	COG2707	UPF0756 membrane protein
RI02_13310	COG0628	permease
RI02_13315	COG3030	protein affecting phage T7 exclusion by the F plasmid
RI02_13325	COG0205	6-phosphofructokinase activity
RI02_13330	COG0825	malonyl-CoA metabolic process
RI02_13335	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
RI02_13340	COG0281	malic enzyme
RI02_13345	COG0587	DNA-directed DNA polymerase activity
RI02_13365	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
RI02_13380	COG4109	DRTGG domain
RI02_13385	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RI02_13390	COG1028	Short-chain dehydrogenase reductase Sdr
RI02_13400	COG0165	Argininosuccinate lyase
RI02_13405	COG0137	argininosuccinate synthase activity
RI02_13410	COG0521	Mo-molybdopterin cofactor biosynthetic process
RI02_13415	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RI02_13420	COG0827	DNA restriction-modification system
RI02_13425	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
RI02_13430	COG3874	Sporulation protein YtfJ
RI02_13440	COG1714	RDD family
RI02_13445	COG0616	signal peptide processing
RI02_13450	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RI02_13460	COG3239	Fatty acid desaturase
RI02_13465	COG4585	Histidine kinase
RI02_13470	COG2197	response regulator
RI02_13475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RI02_13480	COG0745	RESPONSE REGULATOR receiver
RI02_13485	COG2205	protein histidine kinase activity
RI02_13490	COG1136	(ABC) transporter
RI02_13495	COG0577	efflux transmembrane transporter activity
RI02_13500	COG0402	S-adenosylhomocysteine deaminase activity
RI02_13505	COG2249	NAD(P)H dehydrogenase (quinone) activity
RI02_13520	COG1279	arginine transmembrane transporter activity
RI02_13525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RI02_13535	COG0301	tRNA thio-modification
RI02_13540	COG1104	cysteine desulfurase activity
RI02_13545	COG1114	Component of the transport system for branched-chain amino acids
RI02_13550	COG1114	Component of the transport system for branched-chain amino acids
RI02_13555	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
RI02_13560	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RI02_13565	COG1309	transcriptional regulator
RI02_13570	COG1956	GAF domain-containing protein
RI02_13575	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
RI02_13585	COG1335	isochorismatase
RI02_13595	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
RI02_13600	COG2329	Antibiotic biosynthesis monooxygenase
RI02_13605	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
RI02_13610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RI02_13615	COG0454	-acetyltransferase
RI02_13620	COG0517	IMP dehydrogenase activity
RI02_13625	COG0123	including yeast histone deacetylase and acetoin utilization protein
RI02_13630	COG1609	Transcriptional regulator
RI02_13635	COG1605	Chorismate mutase
RI02_13635	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
RI02_13640	COG3118	belongs to the thioredoxin family
RI02_13645	COG4980	gas vesicle protein
RI02_13650	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
RI02_13655	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RI02_13660	COG1674	ftsk spoiiie
RI02_13665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RI02_13670	COG4848	Belongs to the UPF0354 family
RI02_13675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RI02_13690	COG1363	Peptidase, m42
RI02_13695	COG5584	Small secreted protein
RI02_13700	COG0281	malic enzyme
RI02_13705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RI02_13710	COG0220	tRNA (guanine-N7-)-methyltransferase activity
RI02_13720	COG0510	thiamine kinase activity
RI02_13725	COG1597	lipid kinase activity
RI02_13735	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
RI02_13740	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RI02_13745	COG3340	Belongs to the peptidase S51 family
RI02_13750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RI02_13755	COG2252	PERMEase
RI02_13760	COG1349	DNA-binding transcription factor activity
RI02_13765	COG1187	pseudouridine synthase activity
RI02_13770	COG2244	polysaccharide biosynthetic process
RI02_13775	COG2081	HI0933 family
RI02_13785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RI02_13790	COG3196	Protein conserved in bacteria
RI02_13800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RI02_13805	COG5578	integral membrane protein
RI02_13810	COG0673	inositol 2-dehydrogenase activity
RI02_13815	COG1653	transport
RI02_13820	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
RI02_13825	COG4209	transmembrane transport
RI02_13830	COG2207	Transcriptional regulator
RI02_13835	COG1733	regulation of RNA biosynthetic process
RI02_13840	COG2814	Major facilitator Superfamily
RI02_13845	COG0656	L-ascorbic acid biosynthetic process
RI02_13850	COG1653	transport
RI02_13855	COG0395	ABC-type sugar transport system, permease component
RI02_13860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RI02_13865	COG1073	alpha beta
RI02_13870	COG0495	leucyl-tRNA aminoacylation
RI02_13880	COG1366	Belongs to the anti-sigma-factor antagonist family
RI02_13880	COG2202	Pas domain
RI02_13885	COG2433	Pfam Transposase IS66
RI02_13890	COG0577	efflux transmembrane transporter activity
RI02_13895	COG1136	(ABC) transporter
RI02_13905	COG1131	(ABC) transporter
RI02_13910	COG1725	Transcriptional regulator
RI02_13930	COG1242	4 iron, 4 sulfur cluster binding
RI02_13935	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
RI02_13940	COG4326	sporulation control protein
RI02_13950	COG2267	carboxylic ester hydrolase activity
RI02_13955	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
RI02_13960	COG0367	asparagine synthase
RI02_13965	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
RI02_13970	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
RI02_13980	COG1506	peptidase
RI02_13985	COG1233	COG1233 Phytoene dehydrogenase and related
RI02_14005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RI02_14010	COG1116	anion transmembrane transporter activity
RI02_14015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RI02_14020	COG0494	nUDIX hydrolase
RI02_14025	COG2310	stress, protein
RI02_14040	COG4824	toxin secretion phage lysis holin
RI02_14050	COG0783	Belongs to the Dps family
RI02_14065	COG1854	S-ribosylhomocysteine lyase activity
RI02_14070	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
RI02_14075	COG0288	reversible hydration of carbon dioxide
RI02_14080	COG3443	Belongs to the bacterial solute-binding protein 9 family
RI02_14080	COG0803	Belongs to the bacterial solute-binding protein 9 family
RI02_14095	COG1271	oxidase subunit
RI02_14100	COG1294	oxidase, subunit
RI02_14115	COG4948	Mandelate Racemase Muconate Lactonizing
RI02_14120	COG0318	PFAM AMP-dependent synthetase and ligase
RI02_14125	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
RI02_14130	COG0596	Alpha beta hydrolase
RI02_14135	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
RI02_14140	COG1169	isochorismate synthase
RI02_14145	COG1575	Belongs to the MenA family. Type 1 subfamily
RI02_14150	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
RI02_14280	COG3859	Proton-coupled thiamine transporter YuaJ
RI02_14290	COG1247	-acetyltransferase
RI02_14295	COG3339	Conserved Protein
RI02_14300	COG0772	Belongs to the SEDS family
RI02_14305	COG0772	Belongs to the SEDS family
RI02_14310	COG2268	Band 7 protein
RI02_14315	COG1585	Membrane protein implicated in regulation of membrane protease activity
RI02_14320	COG2318	DinB family
RI02_14325	COG1454	alcohol dehydrogenase
RI02_14330	COG1012	belongs to the aldehyde dehydrogenase family
RI02_14335	COG1510	regulation of RNA biosynthetic process
RI02_14350	COG3409	Peptidoglycan-binding domain 1 protein
RI02_14350	COG5632	N-Acetylmuramoyl-L-alanine amidase
RI02_14405	COG3778	Protein conserved in bacteria
RI02_14410	COG3299	homolog of phage Mu protein gp47
RI02_14415	COG3628	GPW Gp25 family protein
RI02_14425	COG4193	domain, Protein
RI02_14430	COG1652	LysM domain
RI02_14435	COG5280	Phage tail tape measure protein TP901
RI02_14435	COG3953	SLT domain
RI02_14435	COG5280	Phage tail tape measure protein TP901
RI02_14435	COG3953	SLT domain
RI02_14490	COG4653	Phage capsid family
RI02_14495	COG0338	D12 class N6 adenine-specific DNA methyltransferase
RI02_14500	COG5518	Phage portal protein
RI02_14505	COG1783	phage Terminase large subunit
RI02_14510	COG5484	DNA packaging
RI02_14515	COG1595	DNA-templated transcription, initiation
RI02_14525	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
RI02_14540	COG1396	sequence-specific DNA binding
RI02_14550	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
RI02_14565	COG0628	permease
RI02_14575	COG0673	inositol 2-dehydrogenase activity
RI02_14580	COG0693	protein deglycase activity
RI02_14585	COG0840	transmembrane signaling receptor activity
RI02_14590	COG0840	transmembrane signaling receptor activity
RI02_14595	COG0840	transmembrane signaling receptor activity
RI02_14600	COG0840	transmembrane signaling receptor activity
RI02_14615	COG2070	2-Nitropropane dioxygenase
RI02_14620	COG0432	Pfam Uncharacterised protein family UPF0047
RI02_14625	COG1253	flavin adenine dinucleotide binding
RI02_14630	COG2738	Putative neutral zinc metallopeptidase
RI02_14640	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RI02_14655	COG0166	Belongs to the GPI family
RI02_14660	COG1979	alcohol dehydrogenase
RI02_14665	COG1979	alcohol dehydrogenase
RI02_14670	COG2155	Conserved Protein
RI02_14675	COG1098	S1 RNA binding domain
RI02_14680	COG0436	Aminotransferase
RI02_14685	COG1522	sequence-specific DNA binding
RI02_14690	COG2267	carboxylic ester hydrolase activity
RI02_14700	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
RI02_14705	COG2205	protein histidine kinase activity
RI02_14715	COG5018	Exonuclease
RI02_14720	COG2814	Major facilitator Superfamily
RI02_14725	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RI02_14730	COG3011	Protein conserved in bacteria
RI02_14740	COG3290	protein histidine kinase activity
RI02_14745	COG4565	transcriptional regulatory protein
RI02_14750	COG1744	ABC transporter substrate-binding protein PnrA-like
RI02_14755	COG3845	ABC transporter
RI02_14760	COG4603	Belongs to the binding-protein-dependent transport system permease family
RI02_14765	COG1079	Belongs to the binding-protein-dependent transport system permease family
RI02_14770	COG3493	citrate carrier protein
RI02_14780	COG2111	Na H antiporter
RI02_14780	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RI02_14785	COG2111	Na H antiporter
RI02_14790	COG1006	Multisubunit Na H antiporter MnhC subunit
RI02_14795	COG0651	ATP synthesis coupled electron transport
RI02_14800	COG1863	multisubunit Na H antiporter MnhE subunit
RI02_14805	COG2212	antiporter activity
RI02_14810	COG1320	monovalent cation:proton antiporter activity
RI02_14815	COG2050	protein possibly involved in aromatic compounds catabolism
RI02_14820	COG2197	response regulator
RI02_14825	COG4585	Histidine kinase
RI02_14835	COG0142	geranyltranstransferase activity
RI02_14850	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
RI02_14855	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RI02_14860	COG1335	isochorismatase
RI02_14865	COG5506	Protein of unknown function (DUF1694)
RI02_14885	COG0628	permease
RI02_14900	COG1418	mRNA catabolic process
RI02_14905	COG1028	Short-chain dehydrogenase reductase Sdr
RI02_14915	COG1511	domain protein
RI02_14920	COG0433	COG0433 Predicted ATPase
RI02_14920	COG1674	ftsk spoiiie
RI02_14925	COG4499	WXG100 protein secretion system (Wss), protein YukC
RI02_14930	COG5417	Belongs to the EsaB family
RI02_14935	COG4842	Belongs to the WXG100 family
RI02_14940	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
RI02_14940	COG2508	Transcriptional regulator
RI02_14945	COG0686	Belongs to the AlaDH PNT family
RI02_14950	COG1268	BioY protein
RI02_14955	COG2056	Na+-H+ antiporter family
RI02_14960	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RI02_14965	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
RI02_14970	COG3584	3D domain protein
RI02_14980	COG1252	NADH dehydrogenase
RI02_14985	COG0492	ferredoxin-NADP+ reductase activity
RI02_15000	COG0789	Transcriptional regulator
RI02_15005	COG5504	Zn-dependent protease
RI02_15010	COG0316	Belongs to the HesB IscA family
RI02_15015	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
RI02_15020	COG4844	belongs to the
RI02_15025	COG1252	NADH dehydrogenase
RI02_15035	COG4837	Protein of unknown function (DUF1462)
RI02_15040	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
RI02_15045	COG1506	peptidase
RI02_15045	COG4946	Tricorn protease homolog
RI02_15045	COG0823	Involved in the tonB-independent uptake of proteins
RI02_15050	COG0083	homoserine kinase activity
RI02_15055	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RI02_15060	COG0460	homoserine dehydrogenase
RI02_15065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RI02_15070	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RI02_15075	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
RI02_15095	COG0647	UMP catabolic process
RI02_15100	COG2445	Protein of unknown function DUF86
RI02_15105	COG4470	Protein conserved in bacteria
RI02_15115	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
RI02_15120	COG0739	heme binding
RI02_15140	COG3377	Domain of unknown function (DUF1805)
RI02_15145	COG0737	Belongs to the 5'-nucleotidase family
RI02_15150	COG1801	Protein of unknown function DUF72
RI02_15155	COG2508	Transcriptional regulator
RI02_15160	COG2140	Oxalate decarboxylase
RI02_15165	COG2814	Major facilitator Superfamily
RI02_15170	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
RI02_15175	COG2356	endonuclease I
RI02_15185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RI02_15190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RI02_15195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RI02_15215	COG5002	protein histidine kinase activity
RI02_15215	COG0642	Histidine kinase
RI02_15220	COG0745	RESPONSE REGULATOR receiver
RI02_15225	COG2311	Membrane
RI02_15235	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RI02_15245	COG1309	transcriptional regulator
RI02_15260	COG0719	Fe-S assembly protein
RI02_15265	COG0822	iron-sulfur transferase activity
RI02_15270	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RI02_15275	COG0719	Fe-S assembly protein
RI02_15280	COG0396	ATPase activity
RI02_15285	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RI02_15290	COG1464	Belongs to the NlpA lipoprotein family
RI02_15295	COG2011	ABC-type metal ion transport system permease component
RI02_15300	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RI02_15310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RI02_15315	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
RI02_15325	COG0509	glycine decarboxylation via glycine cleavage system
RI02_15330	COG1393	Belongs to the ArsC family
RI02_15335	COG1960	acyl-CoA dehydrogenase activity
RI02_15340	COG0183	Belongs to the thiolase family
RI02_15345	COG1250	3-hydroxyacyl-CoA dehydrogenase
RI02_15345	COG1024	Enoyl-CoA hydratase
RI02_15360	COG5577	PFAM Coat F domain
RI02_15370	COG1120	ATPase activity
RI02_15380	COG1028	Short-chain dehydrogenase reductase Sdr
RI02_15390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RI02_15395	COG0745	RESPONSE REGULATOR receiver
RI02_15400	COG2770	Histidine kinase
RI02_15400	COG2205	protein histidine kinase activity
RI02_15405	COG1309	transcriptional regulator
RI02_15410	COG0114	fumarate hydratase activity
RI02_15420	COG0697	spore germination
RI02_15425	COG0814	amino acid
RI02_15440	COG2197	response regulator
RI02_15445	COG4585	Histidine kinase
RI02_15450	COG4758	membrane
RI02_15460	COG1842	Phage shock protein A
RI02_15465	COG4758	membrane
RI02_15470	COG2096	Adenosyltransferase
RI02_15475	COG1028	Short-chain dehydrogenase reductase Sdr
RI02_15480	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
RI02_15505	COG1454	alcohol dehydrogenase
RI02_15510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RI02_15515	COG1120	ATPase activity
RI02_15520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RI02_15525	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RI02_15535	COG2721	sulfolactate sulfo-lyase activity
RI02_15540	COG0246	Mannitol dehydrogenase
RI02_15545	COG1609	Transcriptional regulator
RI02_15550	COG1904	glucuronate isomerase
RI02_15555	COG2205	protein histidine kinase activity
RI02_15560	COG0745	RESPONSE REGULATOR receiver
RI02_15565	COG1120	ATPase activity
RI02_15570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RI02_15575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RI02_15580	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RI02_15585	COG0531	amino acid
RI02_15605	COG1988	membrane-bound metal-dependent
RI02_15610	COG1368	sulfuric ester hydrolase activity
RI02_15615	COG0725	ABC transporter, periplasmic molybdate-binding protein
RI02_15620	COG4149	molybdate abc transporter
RI02_15625	COG0656	L-ascorbic acid biosynthetic process
RI02_15630	COG1940	carbohydrate kinase activity
RI02_15635	COG0025	NhaP-type Na H and K H
RI02_15640	COG2860	membrane
RI02_15645	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
RI02_15650	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RI02_15655	COG2217	Heavy metal translocating P-type atpase
RI02_15660	COG1121	(ABC) transporter
RI02_15665	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RI02_15670	COG0803	Belongs to the bacterial solute-binding protein 9 family
RI02_15680	COG3226	Transcriptional regulator
RI02_15685	COG0784	Response regulator, receiver
RI02_15690	COG4191	Histidine kinase
RI02_15695	COG1027	Aspartate ammonia-lyase
RI02_15710	COG2217	Heavy metal translocating P-type atpase
RI02_15715	COG2608	mercury ion transmembrane transporter activity
RI02_15720	COG1937	Protein conserved in bacteria
RI02_15755	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
RI02_15760	COG0557	exoribonuclease II activity
RI02_15765	COG1647	Serine aminopeptidase, S33
RI02_15770	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RI02_15775	COG2002	toxin-antitoxin pair type II binding
RI02_15780	COG1476	TRANSCRIPTIONal
RI02_15785	COG1396	sequence-specific DNA binding
RI02_15790	COG1396	sequence-specific DNA binding
RI02_15795	COG1733	regulation of RNA biosynthetic process
RI02_15800	COG1174	glycine betaine transport
RI02_15805	COG1732	Glycine betaine
RI02_15810	COG1174	glycine betaine transport
RI02_15815	COG0517	IMP dehydrogenase activity
RI02_15815	COG1125	glycine betaine transport
RI02_15820	COG1510	regulation of RNA biosynthetic process
RI02_15825	COG2095	MarC family integral membrane protein
RI02_15835	COG0456	acetyltransferase
RI02_15855	COG1131	(ABC) transporter
RI02_15865	COG0148	phosphopyruvate hydratase activity
RI02_15870	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
RI02_15875	COG0149	triose-phosphate isomerase activity
RI02_15880	COG0126	phosphoglycerate kinase activity
RI02_15885	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RI02_15890	COG2390	Transcriptional regulator
RI02_15895	COG0833	amino acid
RI02_15900	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RI02_15905	COG3829	transcription factor binding
RI02_15910	COG2186	Transcriptional regulator
RI02_15915	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
RI02_15925	COG0534	Mate efflux family protein
RI02_15930	COG4608	Belongs to the ABC transporter superfamily
RI02_15935	COG0444	Belongs to the ABC transporter superfamily
RI02_15940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RI02_15945	COG0601	transmembrane transport
RI02_15950	COG0747	negative chemotaxis
RI02_15955	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RI02_15960	COG0110	maltose O-acetyltransferase activity
RI02_15965	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RI02_15970	COG2244	polysaccharide biosynthetic process
RI02_15975	COG5039	Polysaccharide pyruvyl transferase
RI02_15980	COG1216	Glycosyl transferase, family 2
RI02_15990	COG0438	transferase activity, transferring glycosyl groups
RI02_15995	COG1215	transferase activity, transferring glycosyl groups
RI02_16000	COG0438	transferase activity, transferring glycosyl groups
RI02_16005	COG1086	Polysaccharide biosynthesis protein
RI02_16010	COG0489	protein tyrosine kinase activity
RI02_16015	COG3944	biosynthesis protein
RI02_16020	COG1396	sequence-specific DNA binding
RI02_16030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RI02_16035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RI02_16040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RI02_16045	COG0726	polysaccharide deacetylase
RI02_16050	COG0488	(ABC) transporter
RI02_16055	COG4608	Belongs to the ABC transporter superfamily
RI02_16070	COG0601	transmembrane transport
RI02_16075	COG0747	negative chemotaxis
RI02_16085	COG1819	glycosyl
RI02_16105	COG0740	serine-type endopeptidase activity
RI02_16110	COG1611	Belongs to the LOG family
RI02_16115	COG1694	Mazg nucleotide pyrophosphohydrolase
RI02_16120	COG0659	secondary active sulfate transmembrane transporter activity
RI02_16125	COG0288	reversible hydration of carbon dioxide
RI02_16130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RI02_16145	COG2162	N-hydroxyarylamine O-acetyltransferase activity
RI02_16150	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RI02_16155	COG1481	regulation of sporulation
RI02_16160	COG0391	Required for morphogenesis under gluconeogenic growth conditions
RI02_16165	COG1660	Displays ATPase and GTPase activities
RI02_16170	COG1051	belongs to the nudix hydrolase family
RI02_16175	COG0492	ferredoxin-NADP+ reductase activity
RI02_16180	COG0791	NLP P60 protein
RI02_16180	COG3883	PFAM NLP P60 protein
RI02_16185	COG0457	Tetratricopeptide repeat
RI02_16190	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
RI02_16190	COG0140	phosphoribosyl-ATP diphosphatase activity
RI02_16195	COG0107	imidazoleglycerol-phosphate synthase activity
RI02_16200	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
RI02_16205	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
RI02_16210	COG0131	Imidazoleglycerol-phosphate dehydratase
RI02_16215	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
RI02_16220	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
RI02_16225	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
RI02_16230	COG4990	cell redox homeostasis
RI02_16240	COG2910	NAD(P)H-binding
RI02_16245	COG1959	2 iron, 2 sulfur cluster binding
RI02_16250	COG0110	maltose O-acetyltransferase activity
RI02_16255	COG0546	phosphoglycolate phosphatase activity
RI02_16260	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
RI02_16270	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
RI02_16275	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RI02_16280	COG0363	glucosamine-6-phosphate deaminase activity
RI02_16285	COG2188	Transcriptional regulator
RI02_16290	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RI02_16295	COG1950	PFAM Membrane protein of
RI02_16300	COG1983	PspC domain protein
RI02_16305	COG3595	metallopeptidase activity
RI02_16320	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
RI02_16330	COG4897	Protein conserved in bacteria
RI02_16335	COG0574	Belongs to the PEP-utilizing enzyme family
RI02_16335	COG3848	Pyruvate phosphate dikinase
RI02_16340	COG1309	transcriptional regulator
RI02_16345	COG2814	Major facilitator Superfamily
RI02_16355	COG0745	RESPONSE REGULATOR receiver
RI02_16360	COG5002	protein histidine kinase activity
RI02_16365	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RI02_16370	COG0463	Glycosyl transferase, family 2
RI02_16375	COG1113	amino acid transport
RI02_16380	COG0778	Nitroreductase
RI02_16385	COG1733	regulation of RNA biosynthetic process
RI02_16390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RI02_16400	COG3409	Peptidoglycan-binding domain 1 protein
RI02_16400	COG0793	Belongs to the peptidase S41A family
RI02_16405	COG0730	response to heat
RI02_16410	COG0791	NLP P60 protein
RI02_16410	COG3883	PFAM NLP P60 protein
RI02_16415	COG2177	Part of the ABC transporter FtsEX involved in
RI02_16420	COG2884	Cell division ATP-binding protein ftsE
RI02_16425	COG2010	Cytochrome c
RI02_16430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RI02_16450	COG0653	protein targeting
RI02_16455	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
RI02_16460	COG0840	transmembrane signaling receptor activity
RI02_16475	COG1516	flagellar protein fliS
RI02_16480	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
RI02_16485	COG1334	flagellar protein FlaG
RI02_16490	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
RI02_16495	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
RI02_16505	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RI02_16510	COG1256	bacterial-type flagellum assembly
RI02_16510	COG4786	Flagellar basal body rod
RI02_16515	COG3418	PFAM FlgN family protein
RI02_16530	COG1040	competence protein
RI02_16540	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
RI02_16545	COG1307	EDD domain protein, DegV family
RI02_16550	COG2197	response regulator
RI02_16555	COG4585	Histidine kinase
RI02_16560	COG1739	Uncharacterized protein family UPF0029
RI02_16565	COG1316	TRANSCRIPTIONal
RI02_16570	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RI02_16575	COG0438	transferase activity, transferring glycosyl groups
RI02_16580	COG1215	transferase activity, transferring glycosyl groups
RI02_16585	COG3206	protein involved in exopolysaccharide biosynthesis
RI02_16590	COG3307	-O-antigen
RI02_16595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RI02_16600	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
RI02_16605	COG0297	glycogen (starch) synthase activity
RI02_16605	COG0438	transferase activity, transferring glycosyl groups
RI02_16610	COG2244	polysaccharide biosynthetic process
RI02_16625	COG2247	cell wall binding repeat
RI02_16625	COG0860	N-Acetylmuramoyl-L-alanine amidase
RI02_16630	COG0860	N-Acetylmuramoyl-L-alanine amidase
RI02_16630	COG2247	cell wall binding repeat
RI02_16635	COG2247	cell wall binding repeat
RI02_16635	COG2385	sporulation resulting in formation of a cellular spore
RI02_16645	COG1316	TRANSCRIPTIONal
RI02_16650	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RI02_16655	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RI02_16660	COG1134	teichoic acid transport
RI02_16665	COG1682	transport, permease protein
RI02_16670	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RI02_16670	COG0463	Glycosyl transferase, family 2
RI02_16675	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RI02_16685	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
RI02_16690	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
RI02_16695	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RI02_16700	COG4193	domain, Protein
RI02_16705	COG1482	cell wall glycoprotein biosynthetic process
RI02_16715	COG1175	transmembrane transport
RI02_16720	COG1653	transport
RI02_16725	COG2197	response regulator
RI02_16730	COG2972	Histidine kinase
RI02_16740	COG0454	-acetyltransferase
RI02_16745	COG0800	Aldolase
RI02_16750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RI02_16755	COG1609	Transcriptional regulator
RI02_16760	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
RI02_16765	COG1028	Short-chain dehydrogenase reductase Sdr
RI02_16770	COG0697	spore germination
RI02_16775	COG0814	amino acid
RI02_16790	COG2814	Major facilitator Superfamily
RI02_16795	COG1316	TRANSCRIPTIONal
RI02_16800	COG0561	phosphatase activity
RI02_16805	COG0791	NLP P60 protein
RI02_16810	COG2843	Capsule synthesis protein
RI02_16820	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RI02_16825	COG0697	spore germination
RI02_16840	COG1609	Transcriptional regulator
RI02_16845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RI02_16850	COG1869	D-ribose catabolic process
RI02_16855	COG1129	ABC transporter
RI02_16860	COG1172	Belongs to the binding-protein-dependent transport system permease family
RI02_16865	COG1879	ABC-type sugar transport system periplasmic component
RI02_16870	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RI02_16875	COG0583	DNA-binding transcription factor activity
RI02_16880	COG0028	Belongs to the TPP enzyme family
RI02_16885	COG3527	Alpha-acetolactate decarboxylase
RI02_16890	COG1522	sequence-specific DNA binding
RI02_16895	COG2059	Chromate
RI02_16900	COG2059	Chromate
RI02_16905	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
RI02_16910	COG4715	Zinc finger, swim domain protein
RI02_16915	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RI02_16920	COG1366	Belongs to the anti-sigma-factor antagonist family
RI02_16920	COG2202	Pas domain
RI02_16925	COG0561	phosphatase activity
RI02_16940	COG1970	mechanosensitive ion channel activity
RI02_16945	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
RI02_16950	COG0457	Tetratricopeptide repeat
RI02_16955	COG4786	Flagellar basal body rod
RI02_16960	COG4786	Flagellar basal body rod
RI02_16965	COG1077	Cell shape determining protein MreB Mrl
RI02_16970	COG1609	Transcriptional regulator
RI02_16975	COG1846	Transcriptional regulator
RI02_16980	COG2814	Major facilitator Superfamily
RI02_16985	COG0671	phosphoesterase, PA-phosphatase related
RI02_16990	COG0477	Major facilitator Superfamily
RI02_16995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RI02_17000	COG0765	amino acid transport
RI02_17005	COG1126	abc transporter atp-binding protein
RI02_17010	COG0004	ammonium transporteR
RI02_17015	COG0347	Belongs to the P(II) protein family
RI02_17020	COG0739	heme binding
RI02_17025	COG1247	-acetyltransferase
RI02_17070	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RI02_17075	COG0523	cobalamin synthesis protein
RI02_17080	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
RI02_17085	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
RI02_17090	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
RI02_17095	COG2223	nitrite transmembrane transporter activity
RI02_17105	COG2304	oxidoreductase activity
RI02_17110	COG2304	oxidoreductase activity
RI02_17115	COG2385	sporulation resulting in formation of a cellular spore
RI02_17120	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RI02_17130	COG4836	Membrane
RI02_17140	COG0355	proton-transporting ATP synthase activity, rotational mechanism
RI02_17145	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
RI02_17150	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
RI02_17155	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
RI02_17160	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RI02_17165	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
RI02_17170	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RI02_17175	COG0356	it plays a direct role in the translocation of protons across the membrane
RI02_17185	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
RI02_17190	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RI02_17195	COG4475	Protein of unknown function (DUF436)
RI02_17200	COG0698	ribose 5-phosphate isomerase
RI02_17205	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RI02_17210	COG1971	Probably functions as a manganese efflux pump
RI02_17215	COG0009	L-threonylcarbamoyladenylate synthase
RI02_17220	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
RI02_17235	COG2890	protein-(glutamine-N5) methyltransferase activity
RI02_17240	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
RI02_17245	COG0789	Transcriptional regulator
RI02_17250	COG0679	Auxin Efflux Carrier
RI02_17255	COG0281	malic enzyme
RI02_17260	COG1435	thymidine kinase activity
RI02_17265	COG0254	rRNA binding
RI02_17270	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
RI02_17275	COG1494	fructose-1,6-bisphosphatase
RI02_17280	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RI02_17285	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RI02_17290	COG0191	fructose-bisphosphate aldolase activity
RI02_17295	COG2204	response regulator
RI02_17300	COG4821	SIS domain
RI02_17305	COG0504	CTP synthase activity
RI02_17310	COG3343	RNA polymerase activity
RI02_17325	COG1960	acyl-CoA dehydrogenase activity
RI02_17330	COG1960	acyl-CoA dehydrogenase activity
RI02_17335	COG1250	3-hydroxyacyl-CoA dehydrogenase
RI02_17340	COG0183	Belongs to the thiolase family
RI02_17345	COG2181	nitrate reductase activity
RI02_17345	COG0247	lactate metabolic process
RI02_17350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RI02_17355	COG4294	response to UV
RI02_17365	COG1619	proteins homologs of microcin C7 resistance protein MccF
RI02_17375	COG1132	(ABC) transporter
RI02_17380	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RI02_17385	COG1619	proteins homologs of microcin C7 resistance protein MccF
RI02_17390	COG0018	arginyl-trna synthetase
RI02_17395	COG4506	Protein conserved in bacteria
RI02_17405	COG0010	Belongs to the arginase family
RI02_17410	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
RI02_17415	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RI02_17425	COG1994	Peptidase M50
RI02_17430	COG1942	4-Oxalocrotonate Tautomerase
RI02_17440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RI02_17445	COG0583	DNA-binding transcription factor activity
RI02_17450	COG0431	NADPH-dependent FMN reductase
RI02_17455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RI02_17460	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RI02_17465	COG0454	-acetyltransferase
RI02_17470	COG0765	amino acid transport
RI02_17480	COG0765	amino acid transport
RI02_17485	COG1126	abc transporter atp-binding protein
RI02_17490	COG3465	dGTPase activity
RI02_17495	COG1078	dGTPase activity
RI02_17500	COG4844	belongs to the
RI02_17550	COG5444	nuclease activity
RI02_17580	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
RI02_17590	COG0280	phosphate acetyltransferase
RI02_17600	COG2814	Major facilitator Superfamily
RI02_17605	COG1522	sequence-specific DNA binding
RI02_17610	COG2814	Major facilitator Superfamily
RI02_17615	COG0077	Prephenate dehydratase
RI02_17620	COG1917	Cupin 2, conserved barrel domain protein
RI02_17625	COG1028	Short-chain dehydrogenase reductase Sdr
RI02_17630	COG0151	Belongs to the GarS family
RI02_17635	COG0436	Aminotransferase
RI02_17640	COG1028	Short-chain dehydrogenase reductase Sdr
RI02_17645	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
RI02_17650	COG1091	dTDP-4-dehydrorhamnose reductase activity
RI02_17655	COG1088	dTDP-glucose 4,6-dehydratase activity
RI02_17660	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
RI02_17665	COG3980	spore coat polysaccharide biosynthesis protein
RI02_17670	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
RI02_17675	COG2089	acid synthase
RI02_17680	COG0456	acetyltransferase
RI02_17685	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RI02_17690	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RI02_17695	COG0463	Glycosyl transferase, family 2
RI02_17715	COG2363	Small membrane protein
RI02_17720	COG2233	PERMEase
RI02_17730	COG1012	belongs to the aldehyde dehydrogenase family
RI02_17735	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
RI02_17740	COG1216	Glycosyl transferase, family 2
RI02_17750	COG0351	phosphomethylpyrimidine kinase
RI02_17765	COG1621	beta-fructofuranosidase activity
RI02_17770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RI02_17770	COG1263	PTS System
RI02_17775	COG3711	transcriptional antiterminator
RI02_17785	COG1404	Belongs to the peptidase S8 family
RI02_17795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RI02_17800	COG0778	Nitroreductase
RI02_17805	COG0772	Belongs to the SEDS family
RI02_17815	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
RI02_17820	COG1845	cytochrome c oxidase, subunit III
RI02_17825	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RI02_17830	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
RI02_17840	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
RI02_17845	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RI02_17850	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
RI02_17865	COG2246	polysaccharide biosynthetic process
RI02_17895	COG0457	Tetratricopeptide repeat
RI02_17910	COG3162	membrane
RI02_17915	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RI02_17935	COG0352	thiamine-phosphate diphosphorylase activity
RI02_17940	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
RI02_17945	COG0583	DNA-binding transcription factor activity
RI02_17950	COG1380	Effector of murein hydrolase LrgA
RI02_17955	COG1346	cytolysis
RI02_17960	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
RI02_17965	COG0346	lactoylglutathione lyase activity
RI02_17975	COG0765	amino acid transport
RI02_17980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RI02_17985	COG0457	Tetratricopeptide repeat
RI02_17990	COG2357	RelA SpoT domain protein
RI02_17995	COG1172	Belongs to the binding-protein-dependent transport system permease family
RI02_18000	COG1129	ABC transporter
RI02_18010	COG3420	alginic acid biosynthetic process
RI02_18015	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RI02_18030	COG1486	melibiose metabolic process
RI02_18035	COG1447	Phosphotransferase system cellobiose-specific component IIA
RI02_18040	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RI02_18045	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RI02_18050	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RI02_18050	COG3711	transcriptional antiterminator
RI02_18065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RI02_18080	COG1595	DNA-templated transcription, initiation
RI02_18090	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
RI02_18095	COG4988	ABC transporter
RI02_18100	COG1294	oxidase, subunit
RI02_18105	COG1271	oxidase subunit
RI02_18110	COG1120	ATPase activity
RI02_18115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RI02_18120	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
RI02_18125	COG4509	Sortase family
RI02_18150	COG5386	Cell surface protein
RI02_18155	COG5386	Cell surface protein
RI02_18160	COG1733	regulation of RNA biosynthetic process
RI02_18165	COG2514	catechol 2,3-dioxygenase activity
RI02_18170	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RI02_18170	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RI02_18175	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RI02_18175	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RI02_18185	COG0726	polysaccharide deacetylase
RI02_18190	COG1447	Phosphotransferase system cellobiose-specific component IIA
RI02_18195	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RI02_18200	COG2723	6-phospho-beta-galactosidase activity
RI02_18210	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RI02_18215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RI02_18215	COG3711	transcriptional antiterminator
RI02_18240	COG1757	Na H antiporter
RI02_18245	COG1027	Aspartate ammonia-lyase
RI02_18250	COG0252	asparaginase activity
RI02_18255	COG1396	sequence-specific DNA binding
RI02_18280	COG4842	Belongs to the WXG100 family
RI02_18285	COG2195	Cleaves the N-terminal amino acid of tripeptides
RI02_18300	COG1737	Transcriptional regulator
RI02_18305	COG2084	Dehydrogenase
RI02_18315	COG2610	gluconate transmembrane transporter activity
RI02_18320	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
RI02_18345	COG2723	6-phospho-beta-galactosidase activity
RI02_18350	COG1263	PTS System
RI02_18350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RI02_18350	COG2190	(PTS) system
RI02_18355	COG3711	transcriptional antiterminator
RI02_18360	COG3878	Protein conserved in bacteria
RI02_18370	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RI02_18375	COG1122	ATPase activity
RI02_18380	COG4721	ABC-type cobalt transport system, permease component
RI02_18385	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
RI02_18420	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
RI02_18425	COG0778	Nitroreductase
RI02_18430	COG1846	Transcriptional regulator
RI02_18435	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
RI02_18440	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RI02_18445	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
RI02_18450	COG2390	Transcriptional regulator
RI02_18460	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
RI02_18460	COG2755	lipolytic protein G-D-S-L family
RI02_18465	COG0477	Major facilitator Superfamily
RI02_18470	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
RI02_18475	COG2226	methyltransferase
RI02_18485	COG0561	phosphatase activity
RI02_18490	COG0789	Transcriptional regulator
RI02_18495	COG0673	inositol 2-dehydrogenase activity
RI02_18500	COG0840	transmembrane signaling receptor activity
RI02_18505	COG1113	amino acid transport
RI02_18510	COG4335	DNA alkylation repair
RI02_18520	COG1070	Carbohydrate kinase
RI02_18525	COG1737	Transcriptional regulator
RI02_18565	COG0583	DNA-binding transcription factor activity
RI02_18570	COG1609	Transcriptional regulator
RI02_18575	COG2182	Extracellular solute-binding protein
RI02_18580	COG1175	transmembrane transport
RI02_18585	COG3833	ABC-type maltose transport systems, permease component
RI02_18595	COG1874	Beta-galactosidase
RI02_18600	COG2851	Citrate transporter
RI02_18610	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
RI02_18615	COG1131	(ABC) transporter
RI02_18620	COG2824	Alkylphosphonate utilization operon protein PhnA
RI02_18625	COG1929	Belongs to the glycerate kinase type-1 family
RI02_18630	COG2610	gluconate transmembrane transporter activity
RI02_18635	COG3835	regulator
RI02_18640	COG1309	transcriptional regulator
RI02_18655	COG1136	(ABC) transporter
RI02_18665	COG0457	Tetratricopeptide repeat
RI02_18670	COG3711	transcriptional antiterminator
RI02_18675	COG2723	6-phospho-beta-galactosidase activity
RI02_18680	COG1263	PTS System
RI02_18680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RI02_18680	COG2190	(PTS) system
RI02_18705	COG0494	nUDIX hydrolase
RI02_18720	COG1113	amino acid transport
RI02_18725	COG1609	Transcriptional regulator
RI02_18735	COG2814	Major facilitator Superfamily
RI02_18740	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RI02_18745	COG2814	Major facilitator Superfamily
RI02_18770	COG5444	nuclease activity
RI02_18785	COG2723	6-phospho-beta-galactosidase activity
RI02_18795	COG2188	Transcriptional regulator
RI02_18810	COG0384	phenazine biosynthesis protein PhzF
RI02_18815	COG0583	DNA-binding transcription factor activity
RI02_18835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RI02_18840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RI02_18865	COG0210	DNA helicase
RI02_18870	COG0210	DNA helicase
RI02_18880	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
RI02_18890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RI02_18900	COG4720	Psort location CytoplasmicMembrane, score
RI02_18920	COG0456	acetyltransferase
RI02_18925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RI02_18930	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
RI02_18935	COG4853	Protein conserved in bacteria
RI02_18940	COG4863	YycH protein
RI02_18945	COG5002	protein histidine kinase activity
RI02_18950	COG0745	RESPONSE REGULATOR receiver
RI02_18975	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RI02_18985	COG2311	Membrane
RI02_18990	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
RI02_18995	COG1309	transcriptional regulator
RI02_19000	COG2124	cytochrome p450
RI02_19005	COG0346	lactoylglutathione lyase activity
RI02_19010	COG0305	Participates in initiation and elongation during chromosome replication
RI02_19025	COG2819	hydrolase of the alpha beta superfamily
RI02_19030	COG2207	Transcriptional regulator
RI02_19030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RI02_19035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RI02_19040	COG2819	hydrolase of the alpha beta superfamily
RI02_19045	COG3093	addiction module antidote protein HigA
RI02_19050	COG2807	transmembrane transport
RI02_19055	COG0359	binds to the 23S rRNA
RI02_19060	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
RI02_19065	COG4241	membrane
RI02_19070	COG1227	inorganic diphosphatase activity
RI02_19080	COG1595	DNA-templated transcription, initiation
RI02_19090	COG0753	catalase activity
RI02_19095	COG0655	NAD(P)H dehydrogenase (quinone) activity
RI02_19100	COG0400	carboxylic ester hydrolase activity
RI02_19105	COG0346	lactoylglutathione lyase activity
RI02_19110	COG1174	glycine betaine transport
RI02_19115	COG1125	glycine betaine transport
RI02_19115	COG0517	IMP dehydrogenase activity
RI02_19120	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
RI02_19125	COG0629	single-stranded DNA binding
RI02_19130	COG0360	Binds together with S18 to 16S ribosomal RNA
RI02_19135	COG0012	GTP binding
RI02_19140	COG4481	Protein conserved in bacteria
RI02_19155	COG3949	Membrane
RI02_19165	COG1475	DNA binding
RI02_19170	COG1192	Involved in chromosome partitioning
RI02_19180	COG1475	DNA binding
RI02_19185	COG0357	Ribosomal RNA small subunit methyltransferase G
RI02_19190	COG0445	tRNA wobble uridine modification
RI02_19195	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
RI02_19200	COG1847	R3H domain protein
RI02_19205	COG0706	membrane insertase activity
RI02_19210	COG0594	ribonuclease P activity
RI02_19215	COG0230	Belongs to the bacterial ribosomal protein bL34 family
RI02_19220	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
RI02_19225	COG0592	DNA-directed DNA polymerase activity
RI02_19230	COG2501	S4 domain
RI02_19235	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RI02_19245	COG0187	DNA topoisomerase II activity
RI02_19250	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RI02_19285	COG0516	GMP reductase activity
RI02_19285	COG0517	IMP dehydrogenase activity
RI02_19290	COG1686	Belongs to the peptidase S11 family
RI02_19295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RI02_19300	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
RI02_19305	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
RI02_19310	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
RI02_19315	COG0840	transmembrane signaling receptor activity
RI02_19325	COG1428	Deoxynucleoside kinase
RI02_19330	COG1428	Deoxynucleoside kinase
RI02_19335	COG1388	LysM domain
RI02_19335	COG3858	chitin binding
RI02_19340	COG1335	isochorismatase
RI02_19345	COG0590	tRNA wobble adenosine to inosine editing
RI02_19355	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RI02_19360	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
RI02_19365	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO