locus-tag	class	description
EVS87_000010	COG4463	regulation of RNA biosynthetic process
EVS87_000015	COG3880	PFAM UvrB UvrC protein
EVS87_000020	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EVS87_000025	COG0542	response to heat
EVS87_000030	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EVS87_000035	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EVS87_000040	COG4956	integral membrane protein (PIN domain superfamily)
EVS87_000045	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EVS87_000050	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EVS87_000055	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EVS87_000060	COG1045	serine acetyltransferase
EVS87_000065	COG0215	cysteine-tRNA ligase activity
EVS87_000070	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EVS87_000075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EVS87_000080	COG3688	RNA-binding protein containing a PIN domain
EVS87_000085	COG1595	DNA-templated transcription, initiation
EVS87_000090	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EVS87_000095	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EVS87_000100	COG0250	Participates in transcription elongation, termination and antitermination
EVS87_000105	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EVS87_000110	COG0081	regulation of translation
EVS87_000115	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EVS87_000120	COG0222	ribosome binding
EVS87_000125	COG2813	Specifically methylates the guanine in position
EVS87_000130	COG0085	RNA polymerase activity
EVS87_000135	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EVS87_000140	COG1358	cellular component organization or biogenesis
EVS87_000145	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EVS87_000150	COG0049	tRNA binding
EVS87_000155	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EVS87_000160	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EVS87_000165	COG0596	Alpha beta hydrolase
EVS87_000170	COG0051	transcription antitermination factor activity, RNA binding
EVS87_000175	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EVS87_000180	COG0088	Forms part of the polypeptide exit tunnel
EVS87_000185	COG0089	rRNA binding
EVS87_000190	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EVS87_000195	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EVS87_000200	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EVS87_000205	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EVS87_000210	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EVS87_000215	COG0255	Belongs to the universal ribosomal protein uL29 family
EVS87_000220	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EVS87_000225	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EVS87_000230	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EVS87_000235	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EVS87_000240	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EVS87_000245	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EVS87_000250	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EVS87_000255	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EVS87_000260	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EVS87_000265	COG1841	ribosomal large subunit assembly
EVS87_000270	COG0200	Binds to the 23S rRNA
EVS87_000275	COG0201	protein transport
EVS87_000280	COG0563	adenylate kinase activity
EVS87_000285	COG0024	Methionine aminopeptidase
EVS87_000295	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EVS87_000300	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EVS87_000305	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EVS87_000310	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EVS87_000315	COG0202	RNA polymerase activity
EVS87_000320	COG0203	ribosomal protein L17
EVS87_000325	COG1122	ATPase activity
EVS87_000330	COG1122	ATPase activity
EVS87_000335	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EVS87_000340	COG0101	tRNA pseudouridine synthase activity
EVS87_000345	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EVS87_000350	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EVS87_000355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EVS87_000385	COG0860	N-Acetylmuramoyl-L-alanine amidase
EVS87_000390	COG0489	protein tyrosine kinase activity
EVS87_000400	COG2194	sulfuric ester hydrolase activity
EVS87_000405	COG0726	polysaccharide deacetylase
EVS87_000435	COG0659	secondary active sulfate transmembrane transporter activity
EVS87_000440	COG0385	Bile acid
EVS87_000445	COG3876	Protein conserved in bacteria
EVS87_000450	COG1472	Belongs to the glycosyl hydrolase 3 family
EVS87_000455	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EVS87_000460	COG1263	PTS System
EVS87_000460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EVS87_000465	COG1737	Transcriptional regulator
EVS87_000470	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EVS87_000505	COG1595	DNA-templated transcription, initiation
EVS87_000510	COG5662	AntiSigma factor
EVS87_000515	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EVS87_000520	COG4856	YbbR-like protein
EVS87_000525	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EVS87_000530	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EVS87_000550	COG1131	(ABC) transporter
EVS87_000560	COG1136	(ABC) transporter
EVS87_000560	COG0577	efflux transmembrane transporter activity
EVS87_000570	COG1695	Transcriptional regulator
EVS87_000580	COG1131	(ABC) transporter
EVS87_000590	COG1413	lyase activity
EVS87_000595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EVS87_000610	COG2311	Membrane
EVS87_000630	COG1476	TRANSCRIPTIONal
EVS87_000640	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EVS87_000645	COG2207	Transcriptional regulator
EVS87_000650	COG1309	transcriptional regulator
EVS87_000665	COG1113	amino acid transport
EVS87_000670	COG0584	glycerophosphoryl diester phosphodiesterase
EVS87_000675	COG2271	Major facilitator Superfamily
EVS87_000685	COG1331	Highly conserved protein containing a thioredoxin domain
EVS87_000700	COG0640	Transcriptional regulator
EVS87_000715	COG1937	Protein conserved in bacteria
EVS87_000720	COG2210	Belongs to the sulfur carrier protein TusA family
EVS87_000730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EVS87_000730	COG0425	Belongs to the sulfur carrier protein TusA family
EVS87_000735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EVS87_000735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EVS87_000740	COG0425	Belongs to the sulfur carrier protein TusA family
EVS87_000745	COG0730	response to heat
EVS87_000750	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EVS87_000755	COG2814	Major facilitator Superfamily
EVS87_000770	COG1846	Transcriptional regulator
EVS87_000780	COG1683	Conserved Protein
EVS87_000790	COG0656	L-ascorbic acid biosynthetic process
EVS87_000795	COG0371	Dehydrogenase
EVS87_000805	COG0531	amino acid
EVS87_000815	COG3711	transcriptional antiterminator
EVS87_000820	COG2190	(PTS) system
EVS87_000820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EVS87_000820	COG1263	PTS System
EVS87_000825	COG2723	6-phospho-beta-galactosidase activity
EVS87_000835	COG1271	oxidase subunit
EVS87_000840	COG1294	oxidase, subunit
EVS87_000845	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EVS87_000850	COG4988	ABC transporter
EVS87_000860	COG3711	transcriptional antiterminator
EVS87_000860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EVS87_000865	COG1940	carbohydrate kinase activity
EVS87_000870	COG0383	alpha-mannosidase activity
EVS87_000875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EVS87_000880	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EVS87_000885	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EVS87_000885	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EVS87_000890	COG1404	Belongs to the peptidase S8 family
EVS87_000905	COG0833	amino acid
EVS87_000910	COG2040	homocysteine
EVS87_000915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EVS87_000925	COG1695	Transcriptional regulator
EVS87_000935	COG2814	Major facilitator Superfamily
EVS87_000955	COG1404	Belongs to the peptidase S8 family
EVS87_000965	COG1309	transcriptional regulator
EVS87_000970	COG1917	Cupin 2, conserved barrel domain protein
EVS87_000980	COG0601	transmembrane transport
EVS87_000990	COG4172	Belongs to the ABC transporter superfamily
EVS87_000995	COG2217	Heavy metal translocating P-type atpase
EVS87_001005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EVS87_001010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EVS87_001015	COG1120	ATPase activity
EVS87_001020	COG1846	Transcriptional regulator
EVS87_001025	COG0318	PFAM AMP-dependent synthetase and ligase
EVS87_001030	COG0531	amino acid
EVS87_001040	COG0596	Alpha beta hydrolase
EVS87_001045	COG1115	amino acid carrier protein
EVS87_001050	COG2066	Belongs to the glutaminase family
EVS87_001055	COG4191	Histidine kinase
EVS87_001060	COG0784	Response regulator, receiver
EVS87_001065	COG1405	negative regulation of cell septum assembly
EVS87_001065	COG3012	SEC-C Motif Domain Protein
EVS87_001075	COG0667	Aldo Keto reductase
EVS87_001080	COG3290	protein histidine kinase activity
EVS87_001085	COG3279	Response regulator of the LytR AlgR family
EVS87_001090	COG4555	ABC transporter
EVS87_001095	COG1668	transmembrane transport
EVS87_001115	COG3773	Cell wall hydrolase
EVS87_001120	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_001130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EVS87_001135	COG2310	stress, protein
EVS87_001140	COG2310	stress, protein
EVS87_001145	COG2310	stress, protein
EVS87_001150	COG0861	Integral membrane protein TerC family
EVS87_001180	COG3853	Toxic anion resistance protein (TelA)
EVS87_001185	COG4175	Glycine betaine
EVS87_001185	COG0517	IMP dehydrogenase activity
EVS87_001190	COG4176	ABC-type proline glycine betaine transport system permease component
EVS87_001195	COG2113	Glycine betaine
EVS87_001210	COG1473	amidohydrolase
EVS87_001215	COG1288	antiporter activity
EVS87_001220	COG0039	L-malate dehydrogenase activity
EVS87_001225	COG1620	l-lactate permease
EVS87_001230	COG1609	Transcriptional regulator
EVS87_001235	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EVS87_001240	COG0561	phosphatase activity
EVS87_001245	COG0673	inositol 2-dehydrogenase activity
EVS87_001250	COG0738	Major facilitator superfamily
EVS87_001255	COG1280	lysine exporter protein (LysE YggA)
EVS87_001270	COG3403	YqcI/YcgG family
EVS87_001275	COG1113	amino acid transport
EVS87_001280	COG3665	Urea carboxylase-associated protein
EVS87_001285	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EVS87_001295	COG1012	belongs to the aldehyde dehydrogenase family
EVS87_001300	COG0710	3-dehydroquinate dehydratase activity
EVS87_001305	COG0028	Belongs to the TPP enzyme family
EVS87_001315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EVS87_001320	COG2271	Major facilitator Superfamily
EVS87_001330	COG1414	Transcriptional regulator
EVS87_001335	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EVS87_001340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EVS87_001350	COG0477	Major facilitator Superfamily
EVS87_001355	COG2226	methyltransferase
EVS87_001360	COG0583	DNA-binding transcription factor activity
EVS87_001370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EVS87_001375	COG3458	cephalosporin-C deacetylase activity
EVS87_001385	COG3541	Predicted nucleotidyltransferase
EVS87_001390	COG0506	proline dehydrogenase activity
EVS87_001395	COG1012	belongs to the aldehyde dehydrogenase family
EVS87_001400	COG2508	Transcriptional regulator
EVS87_001405	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EVS87_001410	COG0765	amino acid transport
EVS87_001415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EVS87_001425	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EVS87_001430	COG1522	sequence-specific DNA binding
EVS87_001435	COG2746	aminoglycoside 3-N-acetyltransferase activity
EVS87_001445	COG3290	protein histidine kinase activity
EVS87_001445	COG0840	transmembrane signaling receptor activity
EVS87_001450	COG3209	COG3209 Rhs family protein
EVS87_001475	COG3842	ATPase activity
EVS87_001480	COG1176	ABC-type spermidine putrescine transport system, permease component I
EVS87_001490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EVS87_001495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EVS87_001500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EVS87_001515	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EVS87_001520	COG0697	spore germination
EVS87_001525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EVS87_001535	COG2207	Transcriptional regulator
EVS87_001535	COG3708	Transcriptional regulator
EVS87_001545	COG2364	Membrane
EVS87_001550	COG0737	Belongs to the 5'-nucleotidase family
EVS87_001555	COG3764	Sortase (surface protein transpeptidase)
EVS87_001560	COG2002	toxin-antitoxin pair type II binding
EVS87_001565	COG1126	abc transporter atp-binding protein
EVS87_001570	COG0765	amino acid transport
EVS87_001575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EVS87_001580	COG0412	Dienelactone hydrolase
EVS87_001585	COG0833	amino acid
EVS87_001590	COG3104	oligopeptide transport
EVS87_001595	COG5434	Belongs to the glycosyl hydrolase 28 family
EVS87_001610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EVS87_001615	COG0765	amino acid transport
EVS87_001620	COG1126	abc transporter atp-binding protein
EVS87_001630	COG2079	MmgE PrpD family protein
EVS87_001640	COG0745	RESPONSE REGULATOR receiver
EVS87_001645	COG5002	protein histidine kinase activity
EVS87_001645	COG3850	Histidine kinase
EVS87_001655	COG1366	Belongs to the anti-sigma-factor antagonist family
EVS87_001660	COG0527	aspartate kinase activity
EVS87_001665	COG2814	Major facilitator Superfamily
EVS87_001670	COG1309	transcriptional regulator
EVS87_001680	COG0640	Transcriptional regulator
EVS87_001685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EVS87_001690	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EVS87_001695	COG0531	amino acid
EVS87_001700	COG1012	belongs to the aldehyde dehydrogenase family
EVS87_001705	COG2249	NAD(P)H dehydrogenase (quinone) activity
EVS87_001710	COG4549	nuclear export factor GLE1
EVS87_001715	COG2372	response to copper ion
EVS87_001715	COG1276	copper resistance
EVS87_001720	COG2213	PTS system mannitol-specific
EVS87_001725	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EVS87_001730	COG0246	Mannitol dehydrogenase
EVS87_001735	COG0840	transmembrane signaling receptor activity
EVS87_001770	COG0346	lactoylglutathione lyase activity
EVS87_001780	COG0561	phosphatase activity
EVS87_001785	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EVS87_001790	COG1914	H( )-stimulated, divalent metal cation uptake system
EVS87_001795	COG4336	lyase activity
EVS87_001800	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EVS87_001805	COG1984	allophanate hydrolase subunit 2
EVS87_001810	COG1414	Transcriptional regulator
EVS87_001815	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EVS87_001820	COG2755	lipolytic protein G-D-S-L family
EVS87_001830	COG3711	transcriptional antiterminator
EVS87_001835	COG2226	methyltransferase
EVS87_001840	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_001845	COG3871	stress protein (general stress protein 26)
EVS87_001865	COG2814	Major facilitator Superfamily
EVS87_001870	COG0551	DNA topoisomerase type I activity
EVS87_001870	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EVS87_001875	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EVS87_001880	COG3706	GGDEF domain
EVS87_001885	COG5298	Protein conserved in bacteria
EVS87_001890	COG1215	transferase activity, transferring glycosyl groups
EVS87_001900	COG0531	amino acid
EVS87_001905	COG0028	Belongs to the TPP enzyme family
EVS87_001925	COG5444	nuclease activity
EVS87_001955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EVS87_001960	COG1914	H( )-stimulated, divalent metal cation uptake system
EVS87_001965	COG2261	transglycosylase associated protein
EVS87_001970	COG2217	Heavy metal translocating P-type atpase
EVS87_001975	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EVS87_001980	COG3290	protein histidine kinase activity
EVS87_001985	COG4565	transcriptional regulatory protein
EVS87_001990	COG1301	dicarboxylic acid transport
EVS87_001995	COG0628	permease
EVS87_002000	COG1301	dicarboxylic acid transport
EVS87_002005	COG1131	(ABC) transporter
EVS87_002010	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EVS87_002025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EVS87_002030	COG1181	Belongs to the D-alanine--D-alanine ligase family
EVS87_002035	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EVS87_002050	COG0513	Belongs to the DEAD box helicase family
EVS87_002055	COG3402	PFAM membrane-flanked domain
EVS87_002060	COG3428	Bacterial PH domain
EVS87_002065	COG0705	Rhomboid family
EVS87_002070	COG0736	holo-[acyl-carrier-protein] synthase activity
EVS87_002075	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EVS87_002080	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EVS87_002085	COG0864	Transcriptional regulator
EVS87_002090	COG2337	Toxic component of a toxin-antitoxin (TA) module
EVS87_002095	COG1366	Belongs to the anti-sigma-factor antagonist family
EVS87_002100	COG1366	Belongs to the anti-sigma-factor antagonist family
EVS87_002105	COG2172	sigma factor antagonist activity
EVS87_002110	COG2208	phosphoserine phosphatase activity
EVS87_002115	COG1366	Belongs to the anti-sigma-factor antagonist family
EVS87_002120	COG2172	sigma factor antagonist activity
EVS87_002125	COG1191	sigma factor activity
EVS87_002130	COG2208	phosphoserine phosphatase activity
EVS87_002135	COG2183	response to ionizing radiation
EVS87_002145	COG3091	SprT-like family
EVS87_002150	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EVS87_002155	COG0022	dehydrogenase e1 component
EVS87_002160	COG0508	dehydrogenase complex catalyzes the overall conversion of
EVS87_002165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EVS87_002170	COG3284	Transcriptional regulator
EVS87_002225	COG1278	Cold shock
EVS87_002230	COG1329	Transcriptional regulator
EVS87_002235	COG1064	alcohol dehydrogenase
EVS87_002240	COG0789	Transcriptional regulator
EVS87_002255	COG0477	Major facilitator Superfamily
EVS87_002270	COG4221	oxidoreductase activity
EVS87_002280	COG0252	asparaginase activity
EVS87_002305	COG2814	Major facilitator Superfamily
EVS87_002310	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EVS87_002315	COG2409	Drug exporters of the RND superfamily
EVS87_002320	COG4585	Histidine kinase
EVS87_002325	COG2197	response regulator
EVS87_002370	COG1309	transcriptional regulator
EVS87_002375	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EVS87_002380	COG1846	Transcriptional regulator
EVS87_002385	COG0778	Nitroreductase
EVS87_002400	COG1396	sequence-specific DNA binding
EVS87_002410	COG0456	acetyltransferase
EVS87_002430	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EVS87_002435	COG0697	spore germination
EVS87_002445	COG1301	dicarboxylic acid transport
EVS87_002485	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EVS87_002490	COG0802	atpase or kinase
EVS87_002495	COG1214	PFAM Peptidase M22, glycoprotease
EVS87_002500	COG0456	acetyltransferase
EVS87_002505	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EVS87_002510	COG0488	(ABC) transporter
EVS87_002515	COG0315	cyclic pyranopterin monophosphate synthase activity
EVS87_002520	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EVS87_002525	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EVS87_002530	COG0805	protein transport
EVS87_002545	COG1266	CAAX protease self-immunity
EVS87_002550	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EVS87_002555	COG0459	protein refolding
EVS87_002565	COG2856	Zn peptidase
EVS87_002575	COG3620	sequence-specific DNA binding
EVS87_002590	COG3645	SOS response
EVS87_002590	COG3646	Phage regulatory protein
EVS87_002610	COG5377	YqaJ viral recombinase family
EVS87_002615	COG3723	Recombinational DNA repair protein, rece pathway
EVS87_002630	COG1484	DNA-dependent DNA replication
EVS87_002695	COG1595	DNA-templated transcription, initiation
EVS87_002700	COG3677	Transposase
EVS87_002710	COG5484	DNA packaging
EVS87_002845	COG1846	Transcriptional regulator
EVS87_002850	COG0456	acetyltransferase
EVS87_002855	COG2808	Putative FMN-binding domain
EVS87_002860	COG1876	peptidase activity
EVS87_002885	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EVS87_002890	COG0823	Involved in the tonB-independent uptake of proteins
EVS87_002900	COG2132	Multicopper oxidase
EVS87_002905	COG1113	amino acid transport
EVS87_002910	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EVS87_002915	COG0714	Associated with various cellular activities
EVS87_002920	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EVS87_002925	COG1305	Transglutaminase-like
EVS87_002930	COG0519	Catalyzes the synthesis of GMP from XMP
EVS87_002930	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EVS87_002950	COG3279	Response regulator of the LytR AlgR family
EVS87_002965	COG1595	DNA-templated transcription, initiation
EVS87_002975	COG2814	Major facilitator Superfamily
EVS87_002980	COG0583	DNA-binding transcription factor activity
EVS87_002985	COG2252	PERMEase
EVS87_002990	COG5583	Uncharacterized small protein (DUF2292)
EVS87_003005	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EVS87_003015	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EVS87_003020	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EVS87_003025	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EVS87_003030	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EVS87_003035	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EVS87_003040	COG0047	phosphoribosylformylglycinamidine synthase activity
EVS87_003045	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EVS87_003050	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EVS87_003055	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EVS87_003060	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EVS87_003065	COG0138	bifunctional purine biosynthesis protein purh
EVS87_003070	COG0151	Belongs to the GarS family
EVS87_003090	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EVS87_003095	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EVS87_003100	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EVS87_003105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EVS87_003115	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EVS87_003120	COG4496	protein, YerC YecD
EVS87_003130	COG0069	glutamate synthase activity
EVS87_003145	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EVS87_003150	COG0210	DNA helicase
EVS87_003155	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EVS87_003160	COG4851	CamS sex pheromone cAM373 precursor
EVS87_003170	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EVS87_003175	COG1285	pathogenesis
EVS87_003180	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EVS87_003185	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EVS87_003190	COG0154	amidase activity
EVS87_003195	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EVS87_003200	COG1309	transcriptional regulator
EVS87_003205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EVS87_003215	COG1957	nucleoside hydrolase
EVS87_003220	COG1597	lipid kinase activity
EVS87_003225	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EVS87_003235	COG5444	nuclease activity
EVS87_003240	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EVS87_003255	COG1959	2 iron, 2 sulfur cluster binding
EVS87_003260	COG0492	ferredoxin-NADP+ reductase activity
EVS87_003275	COG1486	melibiose metabolic process
EVS87_003285	COG2211	Major facilitator Superfamily
EVS87_003325	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EVS87_003330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EVS87_003335	COG1442	glycosyl transferase family 8
EVS87_003340	COG1216	Glycosyl transferase, family 2
EVS87_003345	COG1442	glycosyl transferase family 8
EVS87_003350	COG2223	nitrite transmembrane transporter activity
EVS87_003360	COG0471	metal ion transport
EVS87_003375	COG0071	Belongs to the small heat shock protein (HSP20) family
EVS87_003390	COG0531	amino acid
EVS87_003395	COG0463	Glycosyl transferase, family 2
EVS87_003395	COG0457	Tetratricopeptide repeat
EVS87_003400	COG0488	(ABC) transporter
EVS87_003405	COG1469	GTP cyclohydrolase I activity
EVS87_003410	COG0789	Transcriptional regulator
EVS87_003415	COG2814	Major facilitator Superfamily
EVS87_003420	COG0488	(ABC) transporter
EVS87_003425	COG0513	Belongs to the DEAD box helicase family
EVS87_003430	COG2130	NADP-dependent
EVS87_003450	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EVS87_003450	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EVS87_003455	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EVS87_003465	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EVS87_003465	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EVS87_003475	COG3290	protein histidine kinase activity
EVS87_003480	COG4565	transcriptional regulatory protein
EVS87_003485	COG3181	Tripartite tricarboxylate transporter family receptor
EVS87_003490	COG2851	Citrate transporter
EVS87_003500	COG3479	Phenolic acid decarboxylase
EVS87_003505	COG1695	Transcriptional regulator
EVS87_003510	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EVS87_003520	COG1254	Belongs to the acylphosphatase family
EVS87_003525	COG2258	MOSC domain
EVS87_003535	COG0024	Methionine aminopeptidase
EVS87_003540	COG1263	PTS System
EVS87_003540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EVS87_003545	COG3739	integral membrane protein
EVS87_003560	COG1368	sulfuric ester hydrolase activity
EVS87_003565	COG0076	glutamate decarboxylase activity
EVS87_003570	COG0840	transmembrane signaling receptor activity
EVS87_003580	COG1263	PTS System
EVS87_003580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EVS87_003585	COG0366	Alpha amylase catalytic
EVS87_003590	COG2188	Transcriptional regulator
EVS87_003600	COG0737	Belongs to the 5'-nucleotidase family
EVS87_003605	COG0693	protein deglycase activity
EVS87_003610	COG4840	Belongs to the UPF0435 family
EVS87_003615	COG1115	amino acid carrier protein
EVS87_003625	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EVS87_003630	COG4980	gas vesicle protein
EVS87_003635	COG1295	ribonuclease BN
EVS87_003640	COG0477	Major facilitator Superfamily
EVS87_003650	COG0387	Pfam Sodium calcium exchanger
EVS87_003665	COG4152	abc transporter atp-binding protein
EVS87_003690	COG0217	transcriptional regulatory protein
EVS87_003700	COG0668	transmembrane transport
EVS87_003705	COG0535	radical SAM domain protein
EVS87_003715	COG0726	polysaccharide deacetylase
EVS87_003725	COG0598	Magnesium transport protein CorA
EVS87_003735	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EVS87_003740	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EVS87_003755	COG0789	Transcriptional regulator
EVS87_003760	COG2814	Major facilitator Superfamily
EVS87_003810	COG2076	Multidrug Resistance protein
EVS87_003815	COG2076	Multidrug Resistance protein
EVS87_003820	COG1309	transcriptional regulator
EVS87_003830	COG4637	Psort location Cytoplasmic, score
EVS87_003835	COG2755	lipolytic protein G-D-S-L family
EVS87_003840	COG0492	ferredoxin-NADP+ reductase activity
EVS87_003845	COG2169	Transcriptional regulator
EVS87_003850	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EVS87_003855	COG1132	(ABC) transporter
EVS87_003860	COG1742	UPF0060 membrane protein
EVS87_003865	COG1595	DNA-templated transcription, initiation
EVS87_003885	COG2318	DinB family
EVS87_003895	COG1846	Transcriptional regulator
EVS87_003900	COG0392	lysyltransferase activity
EVS87_003900	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EVS87_003920	COG0778	Nitroreductase
EVS87_003935	COG1090	epimerase
EVS87_003940	COG2137	regulation of response to DNA damage stimulus
EVS87_003965	COG0463	Glycosyl transferase, family 2
EVS87_003970	COG4485	Bacterial membrane protein, YfhO
EVS87_003975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EVS87_003990	COG2140	Oxalate decarboxylase
EVS87_004000	COG1191	sigma factor activity
EVS87_004045	COG1988	membrane-bound metal-dependent
EVS87_004050	COG1194	a g-specific adenine glycosylase
EVS87_004060	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_004075	COG3557	Belongs to the UPF0374 family
EVS87_004080	COG1132	(ABC) transporter
EVS87_004085	COG0444	Belongs to the ABC transporter superfamily
EVS87_004090	COG4608	Belongs to the ABC transporter superfamily
EVS87_004095	COG0747	negative chemotaxis
EVS87_004110	COG4129	membrane
EVS87_004115	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EVS87_004120	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EVS87_004125	COG0735	belongs to the Fur family
EVS87_004275	COG1368	sulfuric ester hydrolase activity
EVS87_004280	COG0681	Belongs to the peptidase S26 family
EVS87_004295	COG1116	anion transmembrane transporter activity
EVS87_004300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EVS87_004305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EVS87_004320	COG1131	(ABC) transporter
EVS87_004350	COG3382	B3 4 domain protein
EVS87_004355	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EVS87_004365	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EVS87_004370	COG2766	serine protein kinase
EVS87_004375	COG2718	Belongs to the UPF0229 family
EVS87_004380	COG1566	PFAM secretion protein HlyD family protein
EVS87_004385	COG2814	Major facilitator Superfamily
EVS87_004390	COG0655	NAD(P)H dehydrogenase (quinone) activity
EVS87_004400	COG1278	Cold shock
EVS87_004410	COG3706	GGDEF domain
EVS87_004435	COG5577	PFAM Coat F domain
EVS87_004440	COG5002	protein histidine kinase activity
EVS87_004445	COG1525	nuclease
EVS87_004445	COG4085	toxin activity
EVS87_004445	COG0737	Belongs to the 5'-nucleotidase family
EVS87_004450	COG3764	Sortase (surface protein transpeptidase)
EVS87_004455	COG0564	pseudouridine synthase activity
EVS87_004465	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EVS87_004470	COG3153	acetyltransferase
EVS87_004470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EVS87_004490	COG3835	regulator
EVS87_004495	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EVS87_004500	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EVS87_004505	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EVS87_004510	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EVS87_004515	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EVS87_004520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EVS87_004525	COG2203	Gaf domain
EVS87_004525	COG4585	Histidine kinase
EVS87_004530	COG2197	response regulator
EVS87_004545	COG0753	catalase activity
EVS87_004550	COG1959	2 iron, 2 sulfur cluster binding
EVS87_004555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EVS87_004555	COG1017	nitric oxide dioxygenase activity
EVS87_004560	COG2719	SpoVR family
EVS87_004565	COG1785	Belongs to the alkaline phosphatase family
EVS87_004570	COG0791	NLP P60 protein
EVS87_004570	COG1388	LysM domain
EVS87_004575	COG0531	amino acid
EVS87_004590	COG1595	DNA-templated transcription, initiation
EVS87_004595	COG0204	Acyl-transferase
EVS87_004600	COG1253	flavin adenine dinucleotide binding
EVS87_004605	COG0789	Transcriptional regulator
EVS87_004610	COG1253	flavin adenine dinucleotide binding
EVS87_004625	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EVS87_004630	COG0584	glycerophosphoryl diester phosphodiesterase
EVS87_004640	COG0668	transmembrane transport
EVS87_004645	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EVS87_004650	COG0726	polysaccharide deacetylase
EVS87_004655	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EVS87_004660	COG0589	response to stress
EVS87_004665	COG1132	(ABC) transporter
EVS87_004670	COG1132	(ABC) transporter
EVS87_004680	COG0702	epimerase
EVS87_004690	COG3842	ATPase activity
EVS87_004695	COG2508	Transcriptional regulator
EVS87_004705	COG0189	ligase activity
EVS87_004710	COG0189	ligase activity
EVS87_004715	COG4399	Belongs to the UPF0754 family
EVS87_004720	COG3679	Belongs to the UPF0342 family
EVS87_004725	COG0561	phosphatase activity
EVS87_004730	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EVS87_004740	COG0475	glutathione-regulated potassium exporter activity
EVS87_004745	COG0490	domain, Protein
EVS87_004755	COG1024	Enoyl-CoA hydratase
EVS87_004765	COG0420	3'-5' exonuclease activity
EVS87_004770	COG4717	serine-type aminopeptidase activity
EVS87_004775	COG3481	metal-dependent phosphohydrolase, HD sub domain
EVS87_004785	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EVS87_004815	COG1846	Transcriptional regulator
EVS87_004820	COG4980	gas vesicle protein
EVS87_004835	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EVS87_004840	COG0537	adenosine 5'-monophosphoramidase activity
EVS87_004845	COG1131	(ABC) transporter
EVS87_004850	COG4473	ABC transporter
EVS87_004860	COG1473	amidohydrolase
EVS87_004870	COG2329	Antibiotic biosynthesis monooxygenase
EVS87_004875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EVS87_004880	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EVS87_004895	COG1309	transcriptional regulator
EVS87_004900	COG1511	domain protein
EVS87_004905	COG1363	Peptidase, m42
EVS87_004910	COG1301	dicarboxylic acid transport
EVS87_004920	COG1234	tRNA 3'-trailer cleavage
EVS87_004925	COG0095	Lipoate-protein ligase
EVS87_004930	COG0318	PFAM AMP-dependent synthetase and ligase
EVS87_004940	COG0501	Belongs to the peptidase M48B family
EVS87_004945	COG1404	Belongs to the peptidase S8 family
EVS87_004950	COG0406	alpha-ribazole phosphatase activity
EVS87_004955	COG0840	transmembrane signaling receptor activity
EVS87_004960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EVS87_004960	COG0723	plastoquinol--plastocyanin reductase activity
EVS87_004965	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_004975	COG4903	ComK protein
EVS87_004980	COG4974	Belongs to the 'phage' integrase family
EVS87_004985	COG2856	Zn peptidase
EVS87_004995	COG1396	sequence-specific DNA binding
EVS87_005010	COG3645	SOS response
EVS87_005010	COG3646	Phage regulatory protein
EVS87_005030	COG5377	YqaJ viral recombinase family
EVS87_005035	COG3723	Recombinational DNA repair protein, rece pathway
EVS87_005050	COG1484	DNA-dependent DNA replication
EVS87_005055	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
EVS87_005090	COG3677	Transposase
EVS87_005100	COG5484	DNA packaging
EVS87_005170	COG3953	SLT domain
EVS87_005170	COG5412	phage tail tape measure protein
EVS87_005235	COG1876	peptidase activity
EVS87_005290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EVS87_005295	COG2814	Major facilitator Superfamily
EVS87_005300	COG2732	(Barnase) inhibitor
EVS87_005305	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EVS87_005310	COG4605	iron ion homeostasis
EVS87_005315	COG4604	ABC transporter, ATP-binding protein
EVS87_005320	COG4607	ABC-type enterochelin transport system periplasmic component
EVS87_005325	COG1316	TRANSCRIPTIONal
EVS87_005345	COG0398	Pfam SNARE associated Golgi protein
EVS87_005350	COG0681	Belongs to the peptidase S26 family
EVS87_005355	COG3180	Ammonia monooxygenase
EVS87_005370	COG2259	Doxx family
EVS87_005375	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EVS87_005380	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EVS87_005385	COG1074	ATP-dependent DNA helicase activity
EVS87_005390	COG0420	3'-5' exonuclease activity
EVS87_005395	COG0419	ATPase involved in DNA repair
EVS87_005400	COG1403	HNH endonuclease
EVS87_005440	COG5337	Spore coat protein CotH
EVS87_005455	COG0179	Fumarylacetoacetate (FAA) hydrolase
EVS87_005470	COG0367	asparagine synthase
EVS87_005485	COG1562	ergosterol biosynthetic process
EVS87_005490	COG0534	Mate efflux family protein
EVS87_005495	COG2207	Transcriptional regulator
EVS87_005495	COG1917	Cupin 2, conserved barrel domain protein
EVS87_005520	COG0076	glutamate decarboxylase activity
EVS87_005555	COG1410	methionine synthase
EVS87_005555	COG0646	methionine synthase
EVS87_005560	COG0646	methionine synthase
EVS87_005560	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EVS87_005565	COG1666	GTP binding
EVS87_005570	COG2996	Protein conserved in bacteria
EVS87_005580	COG0840	transmembrane signaling receptor activity
EVS87_005585	COG1307	EDD domain protein, DegV family
EVS87_005590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EVS87_005610	COG0561	phosphatase activity
EVS87_005615	COG1073	alpha beta
EVS87_005620	COG2151	metal-sulfur cluster biosynthetic enzyme
EVS87_005625	COG0277	FAD linked oxidase domain protein
EVS87_005630	COG2271	Major facilitator Superfamily
EVS87_005635	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EVS87_005645	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EVS87_005650	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EVS87_005655	COG0505	Belongs to the CarA family
EVS87_005660	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EVS87_005665	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EVS87_005675	COG2814	Major facilitator Superfamily
EVS87_005685	COG2267	carboxylic ester hydrolase activity
EVS87_005695	COG1744	ABC transporter substrate-binding protein PnrA-like
EVS87_005710	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EVS87_005715	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EVS87_005720	COG5504	Zn-dependent protease
EVS87_005725	COG0444	Belongs to the ABC transporter superfamily
EVS87_005730	COG4608	Belongs to the ABC transporter superfamily
EVS87_005740	COG0601	transmembrane transport
EVS87_005745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EVS87_005755	COG0180	Tryptophanyl-tRNA synthetase
EVS87_005765	COG4166	transmembrane transport
EVS87_005770	COG0601	transmembrane transport
EVS87_005775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EVS87_005780	COG0444	Belongs to the ABC transporter superfamily
EVS87_005785	COG4608	Belongs to the ABC transporter superfamily
EVS87_005795	COG0456	acetyltransferase
EVS87_005800	COG1393	Belongs to the ArsC family
EVS87_005805	COG0861	Integral membrane protein TerC family
EVS87_005810	COG4862	establishment of competence for transformation
EVS87_005815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EVS87_005825	COG1164	Oligoendopeptidase f
EVS87_005840	COG2346	COG2346, Truncated hemoglobins
EVS87_005845	COG0741	lytic transglycosylase activity
EVS87_005850	COG4116	CYTH
EVS87_005860	COG2357	RelA SpoT domain protein
EVS87_005865	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EVS87_005870	COG0564	pseudouridine synthase activity
EVS87_005875	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EVS87_005880	COG0569	domain protein
EVS87_005880	COG0475	glutathione-regulated potassium exporter activity
EVS87_005885	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EVS87_005890	COG0352	thiamine-phosphate diphosphorylase activity
EVS87_005900	COG2104	thiamine diphosphate biosynthetic process
EVS87_005905	COG2022	thiamine diphosphate biosynthetic process
EVS87_005910	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EVS87_005915	COG0351	phosphomethylpyrimidine kinase
EVS87_005920	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EVS87_005975	COG0210	DNA helicase
EVS87_005985	COG2153	protein acetylation
EVS87_005990	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EVS87_005995	COG2382	esterase
EVS87_006000	COG0626	cystathionine gamma-synthase activity
EVS87_006005	COG0626	cystathionine gamma-synthase activity
EVS87_006015	COG0825	malonyl-CoA metabolic process
EVS87_006035	COG2807	transmembrane transport
EVS87_006045	COG0583	DNA-binding transcription factor activity
EVS87_006060	COG0457	Tetratricopeptide repeat
EVS87_006080	COG3173	Aminoglycoside phosphotransferase
EVS87_006085	COG0583	DNA-binding transcription factor activity
EVS87_006105	COG0583	DNA-binding transcription factor activity
EVS87_006110	COG2807	transmembrane transport
EVS87_006120	COG0457	Tetratricopeptide repeat
EVS87_006130	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EVS87_006140	COG1309	transcriptional regulator
EVS87_006150	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EVS87_006155	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EVS87_006175	COG4195	phage-related replication protein
EVS87_006180	COG2856	Zn peptidase
EVS87_006185	COG3409	Peptidoglycan-binding domain 1 protein
EVS87_006185	COG5632	N-Acetylmuramoyl-L-alanine amidase
EVS87_006200	COG0306	phosphate transporter
EVS87_006205	COG1392	Phosphate transport regulator
EVS87_006215	COG0405	Gamma-glutamyltransferase
EVS87_006220	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EVS87_006230	COG4208	sulfate ABC transporter
EVS87_006235	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EVS87_006245	COG3775	system Galactitol-specific IIC component
EVS87_006260	COG1063	alcohol dehydrogenase
EVS87_006265	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EVS87_006270	COG0508	dehydrogenase complex catalyzes the overall conversion of
EVS87_006270	COG0022	dehydrogenase e1 component
EVS87_006275	COG0508	dehydrogenase complex catalyzes the overall conversion of
EVS87_006280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EVS87_006285	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_006290	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_006295	COG2390	Transcriptional regulator
EVS87_006305	COG0531	amino acid
EVS87_006310	COG0346	lactoylglutathione lyase activity
EVS87_006315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EVS87_006320	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EVS87_006325	COG2362	D-Aminopeptidase
EVS87_006330	COG0601	transmembrane transport
EVS87_006335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EVS87_006340	COG0444	Belongs to the ABC transporter superfamily
EVS87_006345	COG4166	transmembrane transport
EVS87_006350	COG1619	proteins homologs of microcin C7 resistance protein MccF
EVS87_006355	COG4948	Mandelate Racemase Muconate Lactonizing
EVS87_006360	COG0791	NLP P60 protein
EVS87_006365	COG4608	Belongs to the ABC transporter superfamily
EVS87_006370	COG1834	amidinotransferase
EVS87_006375	COG1607	acyl-coa hydrolase
EVS87_006380	COG1695	Transcriptional regulator
EVS87_006395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EVS87_006405	COG2076	Multidrug Resistance protein
EVS87_006410	COG2076	Multidrug Resistance protein
EVS87_006420	COG0788	formyltetrahydrofolate deformylase activity
EVS87_006425	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EVS87_006430	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EVS87_006435	COG0457	Tetratricopeptide repeat
EVS87_006445	COG1764	response to oxidative stress
EVS87_006450	COG1846	Transcriptional regulator
EVS87_006455	COG1764	response to oxidative stress
EVS87_006460	COG0590	tRNA wobble adenosine to inosine editing
EVS87_006465	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EVS87_006470	COG1404	Belongs to the peptidase S8 family
EVS87_006485	COG0745	RESPONSE REGULATOR receiver
EVS87_006490	COG5002	protein histidine kinase activity
EVS87_006490	COG3850	Histidine kinase
EVS87_006495	COG3212	peptidase
EVS87_006500	COG3212	peptidase
EVS87_006510	COG2239	Acts as a magnesium transporter
EVS87_006520	COG0583	DNA-binding transcription factor activity
EVS87_006530	COG0789	Transcriptional regulator
EVS87_006540	COG1846	Transcriptional regulator
EVS87_006545	COG5001	Diguanylate cyclase
EVS87_006545	COG3300	MHYT domain
EVS87_006550	COG0586	Pfam SNARE associated Golgi protein
EVS87_006555	COG0861	Integral membrane protein TerC family
EVS87_006560	COG1191	sigma factor activity
EVS87_006580	COG0501	Belongs to the peptidase M48B family
EVS87_006585	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EVS87_006590	COG2323	membrane
EVS87_006600	COG3594	Acyltransferase
EVS87_006605	COG5002	protein histidine kinase activity
EVS87_006610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EVS87_006615	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EVS87_006620	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EVS87_006625	COG0436	Aminotransferase
EVS87_006630	COG1850	ribulose-bisphosphate carboxylase activity
EVS87_006635	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EVS87_006640	COG0235	Class ii aldolase
EVS87_006645	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EVS87_006655	COG3852	Histidine kinase
EVS87_006660	COG1846	Transcriptional regulator
EVS87_006665	COG1360	Flagellar Motor Protein
EVS87_006670	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EVS87_006680	COG0542	response to heat
EVS87_006685	COG3949	Membrane
EVS87_006690	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EVS87_006695	COG0720	synthase
EVS87_006700	COG0602	queuosine metabolic process
EVS87_006705	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EVS87_006715	COG4873	Protein conserved in bacteria
EVS87_006725	COG3773	Cell wall hydrolase
EVS87_006730	COG2244	polysaccharide biosynthetic process
EVS87_006735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EVS87_006740	COG2217	Heavy metal translocating P-type atpase
EVS87_006745	COG0006	proline dipeptidase activity
EVS87_006750	COG1609	Transcriptional regulator
EVS87_006755	COG3711	transcriptional antiterminator
EVS87_006760	COG1263	PTS System
EVS87_006760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EVS87_006760	COG2190	(PTS) system
EVS87_006765	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EVS87_006770	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EVS87_006780	COG1533	DNA photolyase activity
EVS87_006785	COG0840	transmembrane signaling receptor activity
EVS87_006795	COG2084	Dehydrogenase
EVS87_006800	COG2340	Cysteine-rich secretory protein family
EVS87_006805	COG0768	penicillin binding
EVS87_006810	COG4191	Histidine kinase
EVS87_006815	COG0436	Aminotransferase
EVS87_006820	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EVS87_006825	COG1714	RDD family
EVS87_006835	COG0835	chemotaxis
EVS87_006835	COG0784	Response regulator, receiver
EVS87_006850	COG2814	Major facilitator Superfamily
EVS87_006855	COG1376	ErfK ybiS ycfS ynhG family protein
EVS87_006860	COG1408	metallophosphoesterase
EVS87_006865	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_006870	COG2200	EAL domain
EVS87_006875	COG3546	catalase activity
EVS87_006880	COG4703	Protein of unknown function (DUF1797)
EVS87_006885	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EVS87_006895	COG0517	IMP dehydrogenase activity
EVS87_006900	COG0583	DNA-binding transcription factor activity
EVS87_006910	COG0716	FMN binding
EVS87_006920	COG0716	FMN binding
EVS87_006925	COG2171	N-acyltransferase activity
EVS87_006930	COG1473	amidohydrolase
EVS87_006940	COG0668	transmembrane transport
EVS87_006945	COG0450	alkyl hydroperoxide reductase
EVS87_006950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EVS87_006965	COG0746	molybdenum cofactor guanylyltransferase activity
EVS87_006970	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EVS87_006975	COG0303	'Molybdopterin
EVS87_006980	COG1763	Mo-molybdopterin cofactor biosynthetic process
EVS87_006985	COG0314	molybdopterin synthase activity
EVS87_006990	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EVS87_007005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EVS87_007010	COG1136	(ABC) transporter
EVS87_007015	COG0577	efflux transmembrane transporter activity
EVS87_007020	COG1349	DNA-binding transcription factor activity
EVS87_007025	COG1105	Belongs to the carbohydrate kinase PfkB family
EVS87_007030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EVS87_007030	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EVS87_007030	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EVS87_007035	COG0681	Belongs to the peptidase S26 family
EVS87_007045	COG0488	(ABC) transporter
EVS87_007050	COG2309	aminopeptidase activity
EVS87_007055	COG1077	Cell shape determining protein MreB Mrl
EVS87_007060	COG2002	toxin-antitoxin pair type II binding
EVS87_007065	COG3852	Histidine kinase
EVS87_007070	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EVS87_007070	COG2105	PFAM AIG2 family protein
EVS87_007075	COG0569	domain protein
EVS87_007080	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EVS87_007085	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EVS87_007095	COG0561	phosphatase activity
EVS87_007100	COG0242	peptide deformylase activity
EVS87_007115	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EVS87_007120	COG0022	dehydrogenase e1 component
EVS87_007125	COG0508	dehydrogenase complex catalyzes the overall conversion of
EVS87_007130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EVS87_007140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EVS87_007150	COG1982	Orn Lys Arg decarboxylase major
EVS87_007155	COG4476	Belongs to the UPF0223 family
EVS87_007160	COG4493	Belongs to the UPF0637 family
EVS87_007170	COG0483	inositol monophosphate 1-phosphatase activity
EVS87_007185	COG1595	DNA-templated transcription, initiation
EVS87_007215	COG4896	Protein conserved in bacteria
EVS87_007225	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EVS87_007230	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EVS87_007235	COG2066	Belongs to the glutaminase family
EVS87_007240	COG4838	Belongs to the UPF0358 family
EVS87_007245	COG0772	Belongs to the SEDS family
EVS87_007250	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EVS87_007260	COG1612	heme a metabolic process
EVS87_007265	COG0109	protoheme IX farnesyltransferase activity
EVS87_007270	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EVS87_007270	COG2010	Cytochrome c
EVS87_007275	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EVS87_007280	COG1845	cytochrome c oxidase, subunit III
EVS87_007285	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EVS87_007290	COG3336	cytochrome c oxidase
EVS87_007300	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EVS87_007305	COG2340	Cysteine-rich secretory protein family
EVS87_007325	COG3679	Belongs to the UPF0342 family
EVS87_007330	COG4471	UPF0298 protein
EVS87_007335	COG0742	ribosomal rna small subunit methyltransferase
EVS87_007340	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EVS87_007345	COG3314	Sporulation integral membrane protein YlbJ
EVS87_007350	COG1752	Esterase of the alpha-beta hydrolase superfamily
EVS87_007355	COG3480	Lon protease (S16) C-terminal proteolytic domain
EVS87_007365	COG1399	metal-binding, possibly nucleic acid-binding protein
EVS87_007370	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EVS87_007380	COG0454	-acetyltransferase
EVS87_007385	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EVS87_007390	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EVS87_007395	COG2001	Belongs to the MraZ family
EVS87_007400	COG0275	rRNA processing
EVS87_007405	COG4839	cell division protein FtsL
EVS87_007420	COG0768	penicillin binding
EVS87_007425	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EVS87_007430	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EVS87_007435	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EVS87_007440	COG0772	Belongs to the SEDS family
EVS87_007445	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EVS87_007450	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EVS87_007455	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EVS87_007460	COG3879	Bacterial protein of unknown function (DUF881)
EVS87_007465	COG3879	Bacterial protein of unknown function (DUF881)
EVS87_007470	COG3856	small basic protein
EVS87_007475	COG0849	cell division
EVS87_007480	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EVS87_007485	COG4412	M6 family metalloprotease domain protein
EVS87_007485	COG1404	Belongs to the peptidase S8 family
EVS87_007495	COG1191	sigma factor activity
EVS87_007500	COG1191	sigma factor activity
EVS87_007505	COG2390	Transcriptional regulator
EVS87_007520	COG3730	PTS system glucitol sorbitol-specific
EVS87_007525	COG3732	PTS system glucitol sorbitol-specific
EVS87_007535	COG1119	ATPase activity
EVS87_007540	COG1873	PFAM PRC-barrel domain
EVS87_007550	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EVS87_007555	COG1799	cell septum assembly
EVS87_007560	COG0762	integral membrane protein
EVS87_007565	COG2302	S4 RNA-binding domain
EVS87_007570	COG3599	regulation of cell shape
EVS87_007575	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EVS87_007580	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EVS87_007585	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EVS87_007590	COG0564	pseudouridine synthase activity
EVS87_007595	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EVS87_007600	COG2233	PERMEase
EVS87_007605	COG0540	Belongs to the ATCase OTCase family
EVS87_007610	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EVS87_007615	COG0505	Belongs to the CarA family
EVS87_007620	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EVS87_007625	COG0543	2 iron, 2 sulfur cluster binding
EVS87_007630	COG0167	dihydroorotate dehydrogenase activity
EVS87_007635	COG0284	orotidine-5'-phosphate decarboxylase activity
EVS87_007640	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EVS87_007650	COG0175	sulfate reduction
EVS87_007655	COG0306	phosphate transporter
EVS87_007660	COG2046	Belongs to the sulfate adenylyltransferase family
EVS87_007665	COG0529	Catalyzes the synthesis of activated sulfate
EVS87_007670	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EVS87_007675	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
EVS87_007680	COG1648	precorrin-2 dehydrogenase activity
EVS87_007690	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EVS87_007695	COG1561	YicC-like family, N-terminal region
EVS87_007700	COG2052	Domain of unknown function (DUF370)
EVS87_007705	COG0194	GDP metabolic process
EVS87_007710	COG1758	RNA polymerase activity
EVS87_007715	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EVS87_007720	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EVS87_007725	COG0242	peptide deformylase activity
EVS87_007730	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EVS87_007735	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EVS87_007735	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EVS87_007740	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EVS87_007745	COG0631	protein serine/threonine phosphatase activity
EVS87_007750	COG2815	serine threonine protein kinase
EVS87_007750	COG0515	serine threonine protein kinase
EVS87_007755	COG1162	GTPase activity
EVS87_007760	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EVS87_007765	COG1564	THIamine pyrophosphokinase
EVS87_007775	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EVS87_007780	COG1302	Protein conserved in bacteria
EVS87_007785	COG1461	Dihydroxyacetone kinase
EVS87_007790	COG1760	l-serine dehydratase
EVS87_007795	COG1760	l-serine dehydratase
EVS87_007800	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EVS87_007805	COG1349	DNA-binding transcription factor activity
EVS87_007810	COG0416	fatty acid biosynthetic process
EVS87_007815	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EVS87_007820	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_007825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EVS87_007835	COG1196	nuclear chromosome segregation
EVS87_007840	COG0552	protein localization to endoplasmic reticulum
EVS87_007845	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EVS87_007850	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EVS87_007855	COG0228	four-way junction DNA binding
EVS87_007860	COG1837	Belongs to the UPF0109 family
EVS87_007870	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EVS87_007875	COG0336	Belongs to the RNA methyltransferase TrmD family
EVS87_007880	COG0335	large ribosomal subunit rRNA binding
EVS87_007885	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EVS87_007890	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EVS87_007900	COG2257	FlhB HrpN YscU SpaS Family
EVS87_007905	COG0045	succinate-CoA ligase (ADP-forming) activity
EVS87_007910	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EVS87_007915	COG0758	DNA mediated transformation
EVS87_007920	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EVS87_007925	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EVS87_007930	COG4974	Belongs to the 'phage' integrase family
EVS87_007935	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EVS87_007940	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EVS87_007945	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EVS87_007950	COG1815	bacterial-type flagellum-dependent cell motility
EVS87_007955	COG1558	bacterial-type flagellum-dependent cell motility
EVS87_007960	COG1677	Flagellar hook-basal body complex protein FliE
EVS87_007965	COG1766	The M ring may be actively involved in energy transduction
EVS87_007970	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EVS87_007975	COG1317	bacterial-type flagellum organization
EVS87_007980	COG1157	protein secretion by the type III secretion system
EVS87_007985	COG2882	bacterial-type flagellum organization
EVS87_007990	COG3334	PFAM MgtE intracellular
EVS87_007995	COG3144	bacterial-type flagellum assembly
EVS87_008000	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EVS87_008005	COG4786	Flagellar basal body rod
EVS87_008010	COG1582	Flagellar protein (FlbD)
EVS87_008015	COG1580	Controls the rotational direction of flagella during chemotaxis
EVS87_008020	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EVS87_008025	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EVS87_008025	COG1776	CheC inhibitor of MCP methylation
EVS87_008030	COG2201	protein-glutamate methylesterase activity
EVS87_008035	COG3190	flagellar
EVS87_008040	COG1338	Plays a role in the flagellum-specific transport system
EVS87_008045	COG1987	bacterial-type flagellum assembly
EVS87_008050	COG1684	flagellar biosynthetic protein fliR
EVS87_008055	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EVS87_008060	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EVS87_008065	COG1419	protein localization to endoplasmic reticulum
EVS87_008070	COG0455	bacterial-type flagellum organization
EVS87_008075	COG2201	protein-glutamate methylesterase activity
EVS87_008080	COG0643	Histidine kinase
EVS87_008080	COG2198	Histidine kinase
EVS87_008085	COG0835	chemotaxis
EVS87_008090	COG1776	CheC inhibitor of MCP methylation
EVS87_008100	COG1191	sigma factor activity
EVS87_008115	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EVS87_008120	COG0528	UMP kinase activity
EVS87_008125	COG0233	cytoplasmic translational termination
EVS87_008130	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EVS87_008135	COG4589	Belongs to the CDS family
EVS87_008140	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EVS87_008145	COG0750	zinc metalloprotease
EVS87_008150	COG0442	prolyl-tRNA aminoacylation
EVS87_008155	COG2176	DNA-directed DNA polymerase activity
EVS87_008185	COG0779	Required for maturation of 30S ribosomal subunits
EVS87_008190	COG0195	Participates in both transcription termination and antitermination
EVS87_008195	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EVS87_008200	COG1358	cellular component organization or biogenesis
EVS87_008205	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EVS87_008210	COG1550	Protein conserved in bacteria
EVS87_008215	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EVS87_008220	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EVS87_008225	COG0196	riboflavin kinase activity
EVS87_008230	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EVS87_008235	COG1185	polyribonucleotide nucleotidyltransferase activity
EVS87_008240	COG0726	polysaccharide deacetylase
EVS87_008245	COG0612	Peptidase, M16
EVS87_008250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EVS87_008260	COG1132	(ABC) transporter
EVS87_008265	COG1132	(ABC) transporter
EVS87_008300	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
EVS87_008320	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_008325	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_008330	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EVS87_008335	COG1260	myo-inositol-1-phosphate synthase
EVS87_008380	COG0367	asparagine synthase
EVS87_008385	COG1873	PFAM PRC-barrel domain
EVS87_008390	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EVS87_008395	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EVS87_008400	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EVS87_008405	COG0527	aspartate kinase activity
EVS87_008415	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EVS87_008420	COG0740	serine-type endopeptidase activity
EVS87_008430	COG4980	gas vesicle protein
EVS87_008430	COG1674	ftsk spoiiie
EVS87_008435	COG2188	Transcriptional regulator
EVS87_008440	COG2814	Major facilitator Superfamily
EVS87_008445	COG1033	growth of symbiont in host cell
EVS87_008445	COG2409	Drug exporters of the RND superfamily
EVS87_008450	COG0612	Peptidase, M16
EVS87_008455	COG0612	Peptidase, M16
EVS87_008465	COG2409	Drug exporters of the RND superfamily
EVS87_008465	COG1033	growth of symbiont in host cell
EVS87_008470	COG0300	oxidoreductase activity
EVS87_008485	COG1426	Protein conserved in bacteria
EVS87_008490	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EVS87_008495	COG1058	Belongs to the CinA family
EVS87_008495	COG1546	Belongs to the CinA family
EVS87_008500	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EVS87_008505	COG1418	mRNA catabolic process
EVS87_008510	COG1692	metallophosphoesterase
EVS87_008515	COG2359	stage V sporulation protein S
EVS87_008520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EVS87_008525	COG1063	alcohol dehydrogenase
EVS87_008530	COG0156	8-amino-7-oxononanoate synthase activity
EVS87_008535	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EVS87_008540	COG4550	Control of competence regulator ComK, YlbF/YmcA
EVS87_008550	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EVS87_008555	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EVS87_008575	COG1329	Transcriptional regulator
EVS87_008580	COG4195	phage-related replication protein
EVS87_008585	COG0457	Tetratricopeptide repeat
EVS87_008590	COG1404	Belongs to the peptidase S8 family
EVS87_008595	COG4195	phage-related replication protein
EVS87_008600	COG1764	response to oxidative stress
EVS87_008605	COG2076	Multidrug Resistance protein
EVS87_008630	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EVS87_008635	COG1923	regulation of RNA biosynthetic process
EVS87_008650	COG1780	Probably involved in ribonucleotide reductase function
EVS87_008655	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EVS87_008660	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EVS87_008665	COG4112	unkown
EVS87_008675	COG0464	growth
EVS87_008680	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EVS87_008685	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EVS87_008690	COG0789	Transcriptional regulator
EVS87_008695	COG0174	glutamine synthetase
EVS87_008715	COG0457	Tetratricopeptide repeat
EVS87_008735	COG5444	nuclease activity
EVS87_008760	COG5646	InterPro IPR014922
EVS87_008780	COG0457	Tetratricopeptide repeat
EVS87_008790	COG3619	membrane
EVS87_008795	COG1793	dna ligase
EVS87_008795	COG3285	dna ligase
EVS87_008800	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EVS87_008805	COG4876	unkown
EVS87_008815	COG1959	2 iron, 2 sulfur cluster binding
EVS87_008820	COG0702	epimerase
EVS87_008825	COG0247	lactate metabolic process
EVS87_008830	COG1139	Iron-sulfur cluster binding protein
EVS87_008835	COG1556	Lactate utilization protein
EVS87_008855	COG2323	membrane
EVS87_008860	COG1309	transcriptional regulator
EVS87_008865	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EVS87_008865	COG2124	cytochrome p450
EVS87_008870	COG3591	Belongs to the peptidase S1B family
EVS87_008875	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EVS87_008880	COG3209	COG3209 Rhs family protein
EVS87_008885	COG1366	Belongs to the anti-sigma-factor antagonist family
EVS87_008900	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EVS87_008905	COG1388	LysM domain
EVS87_008910	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EVS87_008915	COG4224	UPF0291 protein
EVS87_008920	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EVS87_008930	COG3763	UPF0154 protein
EVS87_008940	COG0785	Cytochrome C biogenesis protein
EVS87_008945	COG4846	Membrane protein involved in cytochrome C biogenesis
EVS87_008955	COG0071	Belongs to the small heat shock protein (HSP20) family
EVS87_008970	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EVS87_008975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EVS87_008995	COG0824	Thioesterase
EVS87_009005	COG4841	protein insertion into membrane
EVS87_009010	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EVS87_009015	COG1832	CoA-binding protein
EVS87_009020	COG0187	DNA topoisomerase II activity
EVS87_009025	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EVS87_009035	COG0738	Major facilitator superfamily
EVS87_009040	COG0473	3-isopropylmalate dehydrogenase activity
EVS87_009045	COG0110	maltose O-acetyltransferase activity
EVS87_009055	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EVS87_009060	COG0640	Transcriptional regulator
EVS87_009070	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EVS87_009075	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EVS87_009085	COG1309	transcriptional regulator
EVS87_009090	COG2249	NAD(P)H dehydrogenase (quinone) activity
EVS87_009095	COG1733	regulation of RNA biosynthetic process
EVS87_009100	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EVS87_009105	COG0251	oxidation-reduction process
EVS87_009145	COG0657	acetylesterase activity
EVS87_009150	COG0789	Transcriptional regulator
EVS87_009155	COG2723	6-phospho-beta-galactosidase activity
EVS87_009160	COG1263	PTS System
EVS87_009160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EVS87_009160	COG2190	(PTS) system
EVS87_009175	COG2205	protein histidine kinase activity
EVS87_009180	COG0745	RESPONSE REGULATOR receiver
EVS87_009190	COG3507	Belongs to the glycosyl hydrolase 43 family
EVS87_009195	COG1012	belongs to the aldehyde dehydrogenase family
EVS87_009200	COG1486	melibiose metabolic process
EVS87_009225	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EVS87_009240	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EVS87_009270	COG5444	nuclease activity
EVS87_009275	COG1846	Transcriptional regulator
EVS87_009280	COG2814	Major facilitator Superfamily
EVS87_009290	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EVS87_009290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EVS87_009290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EVS87_009295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EVS87_009295	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EVS87_009295	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EVS87_009300	COG1105	Belongs to the carbohydrate kinase PfkB family
EVS87_009310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EVS87_009335	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EVS87_009340	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EVS87_009350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EVS87_009355	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EVS87_009360	COG1024	Enoyl-CoA hydratase
EVS87_009365	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EVS87_009370	COG0511	ligase activity, forming carbon-carbon bonds
EVS87_009375	COG0439	Biotin carboxylase
EVS87_009380	COG0318	PFAM AMP-dependent synthetase and ligase
EVS87_009385	COG1960	acyl-CoA dehydrogenase activity
EVS87_009390	COG1649	PFAM Uncharacterised BCR, COG1649
EVS87_009400	COG1349	DNA-binding transcription factor activity
EVS87_009405	COG1942	4-Oxalocrotonate Tautomerase
EVS87_009415	COG3835	regulator
EVS87_009420	COG0277	FAD linked oxidase domain protein
EVS87_009425	COG0247	lactate metabolic process
EVS87_009445	COG0166	Belongs to the GPI family
EVS87_009450	COG2246	polysaccharide biosynthetic process
EVS87_009455	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EVS87_009460	COG0586	Pfam SNARE associated Golgi protein
EVS87_009465	COG1587	Uroporphyrinogen-III synthase
EVS87_009475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EVS87_009490	COG0534	Mate efflux family protein
EVS87_009495	COG2027	D-alanyl-D-alanine carboxypeptidase
EVS87_009500	COG4677	pectinesterase activity
EVS87_009505	COG2323	membrane
EVS87_009510	COG2146	nitrite reductase [NAD(P)H] activity
EVS87_009515	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EVS87_009520	COG0243	molybdopterin cofactor binding
EVS87_009525	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EVS87_009530	COG2223	nitrite transmembrane transporter activity
EVS87_009535	COG0493	'glutamate synthase
EVS87_009540	COG0070	glutamate synthase
EVS87_009540	COG0067	glutamate synthase
EVS87_009540	COG0069	glutamate synthase activity
EVS87_009545	COG0583	DNA-binding transcription factor activity
EVS87_009555	COG1132	(ABC) transporter
EVS87_009560	COG0789	Transcriptional regulator
EVS87_009560	COG4978	Transcriptional regulator
EVS87_009565	COG0454	-acetyltransferase
EVS87_009570	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EVS87_009575	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EVS87_009580	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EVS87_009590	COG0243	molybdopterin cofactor binding
EVS87_009600	COG1070	Carbohydrate kinase
EVS87_009605	COG2115	Belongs to the xylose isomerase family
EVS87_009610	COG1940	carbohydrate kinase activity
EVS87_009620	COG2211	Major facilitator Superfamily
EVS87_009625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EVS87_009630	COG1994	Peptidase M50
EVS87_009650	COG1309	transcriptional regulator
EVS87_009655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EVS87_009660	COG3708	Transcriptional regulator
EVS87_009665	COG2378	regulation of single-species biofilm formation
EVS87_009675	COG0640	Transcriptional regulator
EVS87_009680	COG0531	amino acid
EVS87_009685	COG0741	lytic transglycosylase activity
EVS87_009690	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EVS87_009695	COG2079	MmgE PrpD family protein
EVS87_009700	COG0372	Belongs to the citrate synthase family
EVS87_009705	COG2322	membrane
EVS87_009715	COG1388	LysM domain
EVS87_009715	COG3584	3D domain protein
EVS87_009720	COG0514	ATP-dependent DNA helicase (RecQ)
EVS87_009730	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EVS87_009755	COG1012	belongs to the aldehyde dehydrogenase family
EVS87_009765	COG1657	PFAM Prenyltransferase squalene oxidase
EVS87_009770	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EVS87_009775	COG0385	Bile acid
EVS87_009780	COG0508	dehydrogenase complex catalyzes the overall conversion of
EVS87_009785	COG0567	Dehydrogenase, E1 component
EVS87_009790	COG4548	von Willebrand factor, type A
EVS87_009795	COG0714	Associated with various cellular activities
EVS87_009800	COG2032	superoxide dismutase activity
EVS87_009805	COG0791	NLP P60 protein
EVS87_009805	COG1388	LysM domain
EVS87_009810	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EVS87_009815	COG0534	Mate efflux family protein
EVS87_009820	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EVS87_009825	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EVS87_009835	COG2962	Rard protein
EVS87_009850	COG1733	regulation of RNA biosynthetic process
EVS87_009855	COG0778	Nitroreductase
EVS87_009865	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EVS87_009870	COG3409	Peptidoglycan-binding domain 1 protein
EVS87_009870	COG0793	Belongs to the peptidase S41A family
EVS87_009875	COG2226	methyltransferase
EVS87_009885	COG1876	peptidase activity
EVS87_009890	COG0813	purine-nucleoside phosphorylase activity
EVS87_009900	COG0671	phosphoesterase, PA-phosphatase related
EVS87_009915	COG4479	Belongs to the UPF0346 family
EVS87_009925	COG1509	lysine 2,3-aminomutase activity
EVS87_009930	COG3829	transcription factor binding
EVS87_009935	COG0463	Glycosyl transferase, family 2
EVS87_009950	COG4641	Protein conserved in bacteria
EVS87_009960	COG1086	Polysaccharide biosynthesis protein
EVS87_009965	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EVS87_009970	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EVS87_009975	COG1846	Transcriptional regulator
EVS87_009995	COG4698	Protein conserved in bacteria
EVS87_010000	COG2755	lipolytic protein G-D-S-L family
EVS87_010005	COG1999	signal sequence binding
EVS87_010020	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EVS87_010025	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EVS87_010030	COG1272	protein, Hemolysin III
EVS87_010035	COG0204	Acyl-transferase
EVS87_010040	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EVS87_010045	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EVS87_010050	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EVS87_010060	COG2521	methyltransferase
EVS87_010060	COG2136	Putative SAM-dependent methyltransferase
EVS87_010070	COG0129	dihydroxy-acid dehydratase activity
EVS87_010075	COG1413	lyase activity
EVS87_010080	COG1418	mRNA catabolic process
EVS87_010085	COG0386	Belongs to the glutathione peroxidase family
EVS87_010090	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EVS87_010095	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EVS87_010100	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EVS87_010110	COG1278	Cold shock
EVS87_010125	COG0328	RNA-DNA hybrid ribonuclease activity
EVS87_010130	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EVS87_010135	COG0328	RNA-DNA hybrid ribonuclease activity
EVS87_010145	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EVS87_010155	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EVS87_010165	COG1755	Isoprenylcysteine carboxyl methyltransferase
EVS87_010170	COG3424	synthase
EVS87_010175	COG0726	polysaccharide deacetylase
EVS87_010180	COG2233	PERMEase
EVS87_010185	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EVS87_010190	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EVS87_010195	COG1199	ATP-dependent helicase activity
EVS87_010205	COG0116	Belongs to the methyltransferase superfamily
EVS87_010215	COG3599	regulation of cell shape
EVS87_010220	COG4474	Belongs to the UPF0398 family
EVS87_010230	COG3359	exonuclease
EVS87_010235	COG1205	dead DEAH box helicase
EVS87_010235	COG1111	helicase
EVS87_010240	COG1902	pentaerythritol trinitrate reductase activity
EVS87_010245	COG2190	(PTS) system
EVS87_010250	COG0071	Belongs to the small heat shock protein (HSP20) family
EVS87_010280	COG3331	DNA recombination
EVS87_010285	COG4499	WXG100 protein secretion system (Wss), protein YukC
EVS87_010285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EVS87_010295	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EVS87_010300	COG3935	DnaD domain protein
EVS87_010305	COG0017	Asparaginyl-tRNA synthetase
EVS87_010310	COG5353	protein conserved in bacteria
EVS87_010320	COG1199	ATP-dependent helicase activity
EVS87_010320	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EVS87_010325	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EVS87_010330	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EVS87_010335	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EVS87_010345	COG0617	tRNA 3'-terminal CCA addition
EVS87_010350	COG0438	transferase activity, transferring glycosyl groups
EVS87_010355	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EVS87_010360	COG1803	Methylglyoxal synthase
EVS87_010365	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EVS87_010370	COG1694	Mazg nucleotide pyrophosphohydrolase
EVS87_010375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EVS87_010385	COG4347	Protein of unknown function (DUF1405)
EVS87_010390	COG2010	Cytochrome c
EVS87_010390	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EVS87_010395	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EVS87_010400	COG0723	plastoquinol--plastocyanin reductase activity
EVS87_010410	COG5582	Belongs to the UPF0302 family
EVS87_010415	COG0457	Tetratricopeptide repeat
EVS87_010420	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EVS87_010425	COG0287	Prephenate dehydrogenase
EVS87_010430	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EVS87_010435	COG0159	tryptophan synthase activity
EVS87_010440	COG0133	tryptophan synthase activity
EVS87_010445	COG0135	phosphoribosylanthranilate isomerase activity
EVS87_010450	COG0134	indole-3-glycerol-phosphate synthase activity
EVS87_010455	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EVS87_010465	COG4401	Chorismate mutase type I
EVS87_010470	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EVS87_010475	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EVS87_010480	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EVS87_010485	COG0105	UTP biosynthetic process
EVS87_010490	COG0142	geranyltranstransferase activity
EVS87_010495	COG2226	methyltransferase
EVS87_010500	COG0142	geranyltranstransferase activity
EVS87_010510	COG0302	gtp cyclohydrolase
EVS87_010515	COG0776	regulation of translation
EVS87_010520	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EVS87_010535	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EVS87_010540	COG1160	GTP binding
EVS87_010570	COG1304	FMN binding
EVS87_010575	COG0539	negative regulation of cytoplasmic translation
EVS87_010580	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EVS87_010590	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EVS87_010595	COG2959	enzyme of heme biosynthesis
EVS87_010600	COG3773	Cell wall hydrolase
EVS87_010600	COG3409	Peptidoglycan-binding domain 1 protein
EVS87_010605	COG2339	peptidase activity
EVS87_010610	COG0492	ferredoxin-NADP+ reductase activity
EVS87_010615	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EVS87_010620	COG4862	establishment of competence for transformation
EVS87_010625	COG1408	metallophosphoesterase
EVS87_010635	COG1388	LysM domain
EVS87_010640	COG1266	CAAX protease self-immunity
EVS87_010645	COG0514	ATP-dependent DNA helicase (RecQ)
EVS87_010650	COG4955	Helix-turn-helix domain
EVS87_010655	COG1141	Ferredoxin
EVS87_010660	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EVS87_010665	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EVS87_010680	COG1595	DNA-templated transcription, initiation
EVS87_010685	COG5002	protein histidine kinase activity
EVS87_010690	COG0745	RESPONSE REGULATOR receiver
EVS87_010695	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EVS87_010700	COG1333	cytochrome c biogenesis protein
EVS87_010705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EVS87_010710	COG1187	pseudouridine synthase activity
EVS87_010715	COG0700	Nucleoside recognition
EVS87_010720	COG2715	membrane protein required for spore maturation
EVS87_010725	COG1686	Belongs to the peptidase S11 family
EVS87_010735	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EVS87_010740	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EVS87_010750	COG1547	Domain of unknown function (DUF309)
EVS87_010755	COG0456	acetyltransferase
EVS87_010760	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EVS87_010765	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EVS87_010765	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EVS87_010770	COG0307	riboflavin synthase, alpha
EVS87_010795	COG2814	Major facilitator Superfamily
EVS87_010800	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EVS87_010805	COG4086	secreted protein
EVS87_010810	COG0019	diaminopimelate decarboxylase activity
EVS87_010815	COG0697	spore germination
EVS87_010830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EVS87_010850	COG1191	sigma factor activity
EVS87_010855	COG2172	sigma factor antagonist activity
EVS87_010865	COG1686	Belongs to the peptidase S11 family
EVS87_010870	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EVS87_010875	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EVS87_010880	COG4974	Belongs to the 'phage' integrase family
EVS87_010890	COG0735	belongs to the Fur family
EVS87_010895	COG1300	Membrane
EVS87_010900	COG1404	Belongs to the peptidase S8 family
EVS87_010910	COG2153	protein acetylation
EVS87_010915	COG1379	DNA repair
EVS87_010920	COG0494	nUDIX hydrolase
EVS87_010925	COG0667	Aldo Keto reductase
EVS87_010940	COG1073	alpha beta
EVS87_010945	COG0457	Tetratricopeptide repeat
EVS87_010955	COG4918	Iron-sulphur cluster biosynthesis
EVS87_010960	COG4305	rare lipoprotein A
EVS87_010965	COG0456	acetyltransferase
EVS87_010965	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EVS87_010970	COG0456	acetyltransferase
EVS87_010980	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EVS87_010990	COG2211	Major facilitator Superfamily
EVS87_010995	COG1072	(Pantothenic acid kinase))
EVS87_011000	COG0446	pyridine nucleotide-disulphide oxidoreductase
EVS87_011010	COG0300	oxidoreductase activity
EVS87_011015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EVS87_011020	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EVS87_011030	COG4187	Peptidase family M20/M25/M40
EVS87_011035	COG1902	pentaerythritol trinitrate reductase activity
EVS87_011040	COG0596	Alpha beta hydrolase
EVS87_011045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EVS87_011055	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EVS87_011060	COG2188	Transcriptional regulator
EVS87_011065	COG2723	6-phospho-beta-galactosidase activity
EVS87_011070	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EVS87_011075	COG1447	Phosphotransferase system cellobiose-specific component IIA
EVS87_011080	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EVS87_011090	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_011105	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EVS87_011110	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EVS87_011120	COG0706	membrane insertase activity
EVS87_011125	COG0835	chemotaxis
EVS87_011130	COG2195	Cleaves the N-terminal amino acid of tripeptides
EVS87_011135	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EVS87_011140	COG0346	lactoylglutathione lyase activity
EVS87_011150	COG1376	ErfK ybiS ycfS ynhG family protein
EVS87_011155	COG4129	membrane
EVS87_011160	COG1126	abc transporter atp-binding protein
EVS87_011165	COG0765	amino acid transport
EVS87_011170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EVS87_011180	COG1597	lipid kinase activity
EVS87_011190	COG0508	dehydrogenase complex catalyzes the overall conversion of
EVS87_011195	COG0022	dehydrogenase e1 component
EVS87_011200	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EVS87_011205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EVS87_011210	COG3426	butyrate kinase activity
EVS87_011215	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EVS87_011220	COG0280	phosphate acetyltransferase
EVS87_011225	COG3290	protein histidine kinase activity
EVS87_011225	COG3829	transcription factor binding
EVS87_011235	COG0584	glycerophosphoryl diester phosphodiesterase
EVS87_011240	COG0457	Tetratricopeptide repeat
EVS87_011245	COG0745	RESPONSE REGULATOR receiver
EVS87_011250	COG0750	zinc metalloprotease
EVS87_011255	COG0497	DNA recombination
EVS87_011260	COG1438	arginine binding
EVS87_011265	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EVS87_011270	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EVS87_011275	COG0142	geranyltranstransferase activity
EVS87_011280	COG1722	exodeoxyribonuclease VII activity
EVS87_011285	COG1570	exodeoxyribonuclease VII activity
EVS87_011290	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EVS87_011295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EVS87_011300	COG1302	Protein conserved in bacteria
EVS87_011305	COG0439	Biotin carboxylase
EVS87_011310	COG0511	ligase activity, forming carbon-carbon bonds
EVS87_011350	COG3854	ATPases associated with a variety of cellular activities
EVS87_011360	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EVS87_011365	COG0006	proline dipeptidase activity
EVS87_011370	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EVS87_011380	COG3872	metal-dependent enzyme
EVS87_011390	COG1752	Esterase of the alpha-beta hydrolase superfamily
EVS87_011395	COG1321	iron dependent repressor
EVS87_011400	COG0095	Lipoate-protein ligase
EVS87_011405	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EVS87_011420	COG0745	RESPONSE REGULATOR receiver
EVS87_011425	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EVS87_011430	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EVS87_011435	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EVS87_011440	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EVS87_011465	COG0681	Belongs to the peptidase S26 family
EVS87_011500	COG4970	Tfp pilus assembly protein FimT
EVS87_011505	COG4537	Required for transformation and DNA binding
EVS87_011510	COG1459	type II secretion system
EVS87_011515	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EVS87_011520	COG1366	Belongs to the anti-sigma-factor antagonist family
EVS87_011530	COG1393	Belongs to the ArsC family
EVS87_011540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EVS87_011550	COG0011	TIGRFAM Protein of
EVS87_011555	COG2814	Major facilitator Superfamily
EVS87_011565	COG2866	Carboxypeptidase
EVS87_011570	COG1368	sulfuric ester hydrolase activity
EVS87_011575	COG1940	carbohydrate kinase activity
EVS87_011580	COG4483	Protein conserved in bacteria
EVS87_011585	COG0457	Tetratricopeptide repeat
EVS87_011585	COG0705	Rhomboid family
EVS87_011590	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EVS87_011595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EVS87_011605	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EVS87_011610	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EVS87_011615	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EVS87_011620	COG0581	inorganic phosphate transmembrane transporter activity
EVS87_011625	COG0573	inorganic phosphate transmembrane transporter activity
EVS87_011630	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EVS87_011640	COG0477	Major facilitator Superfamily
EVS87_011645	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EVS87_011650	COG2839	Protein conserved in bacteria
EVS87_011655	COG5521	maltodextrose utilization protein MalA
EVS87_011660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EVS87_011665	COG1388	LysM domain
EVS87_011670	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EVS87_011675	COG4709	membrane
EVS87_011680	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
EVS87_011685	COG1940	carbohydrate kinase activity
EVS87_011690	COG0735	belongs to the Fur family
EVS87_011695	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EVS87_011700	COG1121	(ABC) transporter
EVS87_011705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EVS87_011720	COG0513	Belongs to the DEAD box helicase family
EVS87_011730	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EVS87_011735	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EVS87_011740	COG2384	SAM-dependent methyltransferase
EVS87_011745	COG2010	Cytochrome c
EVS87_011750	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EVS87_011755	COG0358	DNA primase activity
EVS87_011760	COG1671	Belongs to the UPF0178 family
EVS87_011765	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EVS87_011770	COG0517	IMP dehydrogenase activity
EVS87_011775	COG0751	glycine-tRNA ligase activity
EVS87_011780	COG0752	glycyl-tRNA synthetase alpha subunit
EVS87_011785	COG1381	Involved in DNA repair and RecF pathway recombination
EVS87_011795	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EVS87_011800	COG0295	cytidine deaminase activity
EVS87_011805	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EVS87_011810	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EVS87_011815	COG1480	7TM receptor with intracellular HD hydrolase
EVS87_011820	COG1702	phosphate starvation-inducible protein PhoH
EVS87_011825	COG0561	phosphatase activity
EVS87_011845	COG4864	UPF0365 protein
EVS87_011850	COG1030	water channel activity
EVS87_011855	COG1610	YqeY-like protein
EVS87_011860	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EVS87_011865	COG1283	sodium-dependent phosphate transmembrane transporter activity
EVS87_011870	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EVS87_011875	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EVS87_011880	COG2264	protein methyltransferase activity
EVS87_011885	COG0484	heat shock protein binding
EVS87_011890	COG0443	Heat shock 70 kDa protein
EVS87_011895	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EVS87_011900	COG1420	regulation of RNA biosynthetic process
EVS87_011905	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EVS87_011910	COG0481	GTPase activity
EVS87_011920	COG0860	N-Acetylmuramoyl-L-alanine amidase
EVS87_011925	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EVS87_011930	COG0268	Binds directly to 16S ribosomal RNA
EVS87_011935	COG1466	dna polymerase III delta subunit
EVS87_011945	COG2333	competence protein COMEC
EVS87_011945	COG0658	competence protein
EVS87_011950	COG2131	deaminase
EVS87_011955	COG1596	polysaccharide export
EVS87_011955	COG1555	photosystem II stabilization
EVS87_011960	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EVS87_011965	COG2226	methyltransferase
EVS87_011970	COG0799	negative regulation of ribosome biogenesis
EVS87_011975	COG1713	HD superfamily hydrolase involved in NAD metabolism
EVS87_011980	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EVS87_011985	COG1534	Rna-binding protein
EVS87_011990	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EVS87_011995	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EVS87_012000	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EVS87_012010	COG2755	lipolytic protein G-D-S-L family
EVS87_012015	COG0726	polysaccharide deacetylase
EVS87_012020	COG0457	Tetratricopeptide repeat
EVS87_012030	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EVS87_012080	COG3409	Peptidoglycan-binding domain 1 protein
EVS87_012080	COG5632	N-Acetylmuramoyl-L-alanine amidase
EVS87_012115	COG3778	Protein conserved in bacteria
EVS87_012120	COG3299	homolog of phage Mu protein gp47
EVS87_012125	COG3628	GPW Gp25 family protein
EVS87_012135	COG4193	domain, Protein
EVS87_012140	COG1652	LysM domain
EVS87_012145	COG3953	SLT domain
EVS87_012145	COG5280	Phage tail tape measure protein TP901
EVS87_012145	COG5280	Phage tail tape measure protein TP901
EVS87_012145	COG3953	SLT domain
EVS87_012200	COG4653	Phage capsid family
EVS87_012205	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EVS87_012225	COG2369	cell adhesion
EVS87_012230	COG5518	Phage portal protein
EVS87_012235	COG1783	phage Terminase large subunit
EVS87_012240	COG5484	DNA packaging
EVS87_012315	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
EVS87_012325	COG1484	DNA-dependent DNA replication
EVS87_012375	COG1396	sequence-specific DNA binding
EVS87_012380	COG2856	Zn peptidase
EVS87_012400	COG2186	Transcriptional regulator
EVS87_012415	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_012420	COG3958	Transketolase
EVS87_012425	COG3959	Transketolase, thiamine diphosphate binding domain
EVS87_012450	COG0726	polysaccharide deacetylase
EVS87_012485	COG1131	(ABC) transporter
EVS87_012510	COG2160	L-arabinose isomerase activity
EVS87_012525	COG1609	Transcriptional regulator
EVS87_012535	COG1846	Transcriptional regulator
EVS87_012545	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EVS87_012550	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EVS87_012555	COG1733	regulation of RNA biosynthetic process
EVS87_012575	COG3209	COG3209 Rhs family protein
EVS87_012580	COG2602	Beta-lactamase
EVS87_012585	COG1960	acyl-CoA dehydrogenase activity
EVS87_012590	COG1126	abc transporter atp-binding protein
EVS87_012595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EVS87_012600	COG0765	amino acid transport
EVS87_012610	COG1063	alcohol dehydrogenase
EVS87_012620	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_012625	COG1063	alcohol dehydrogenase
EVS87_012630	COG2226	methyltransferase
EVS87_012655	COG0626	cystathionine gamma-synthase activity
EVS87_012660	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EVS87_012665	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EVS87_012670	COG2226	methyltransferase
EVS87_012685	COG0768	penicillin binding
EVS87_012690	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EVS87_012695	COG0572	uridine kinase
EVS87_012715	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EVS87_012720	COG0183	Belongs to the thiolase family
EVS87_012725	COG0318	PFAM AMP-dependent synthetase and ligase
EVS87_012730	COG1268	BioY protein
EVS87_012735	COG3906	Belongs to the UPF0473 family
EVS87_012740	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EVS87_012745	COG4472	Bacterial protein of unknown function (DUF965)
EVS87_012750	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EVS87_012755	COG0628	permease
EVS87_012760	COG1126	abc transporter atp-binding protein
EVS87_012765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EVS87_012770	COG0765	amino acid transport
EVS87_012775	COG0765	amino acid transport
EVS87_012790	COG3881	PFAM PRC-barrel domain
EVS87_012795	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EVS87_012800	COG0457	Tetratricopeptide repeat
EVS87_012805	COG0482	sulfurtransferase activity
EVS87_012810	COG1104	cysteine desulfurase activity
EVS87_012815	COG1959	2 iron, 2 sulfur cluster binding
EVS87_012820	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EVS87_012825	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EVS87_012840	COG0124	histidyl-tRNA synthetase
EVS87_012845	COG3103	Sh3 type 3 domain protein
EVS87_012845	COG4991	sh3 domain protein
EVS87_012845	COG0860	N-Acetylmuramoyl-L-alanine amidase
EVS87_012850	COG1490	D-aminoacyl-tRNA deacylase activity
EVS87_012855	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EVS87_012860	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EVS87_012865	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EVS87_012865	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EVS87_012870	COG5416	Lipopolysaccharide assembly protein A domain
EVS87_012875	COG0490	domain, Protein
EVS87_012880	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EVS87_012880	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EVS87_012890	COG2244	polysaccharide biosynthetic process
EVS87_012895	COG2323	membrane
EVS87_012905	COG1862	Preprotein translocase
EVS87_012910	COG0343	queuine tRNA-ribosyltransferase activity
EVS87_012915	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EVS87_012925	COG2255	four-way junction helicase activity
EVS87_012930	COG0632	four-way junction helicase activity
EVS87_012940	COG2112	serine threonine protein kinase
EVS87_012950	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EVS87_012965	COG1388	LysM domain
EVS87_012970	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EVS87_012975	COG0157	Belongs to the NadC ModD family
EVS87_012980	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EVS87_012985	COG1104	cysteine desulfurase activity
EVS87_012990	COG1827	regulation of RNA biosynthetic process
EVS87_012995	COG0077	Prephenate dehydratase
EVS87_013000	COG4492	Belongs to the UPF0735 family
EVS87_013005	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EVS87_013010	COG3290	protein histidine kinase activity
EVS87_013015	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EVS87_013020	COG2868	ribosomal protein
EVS87_013025	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EVS87_013030	COG1994	Peptidase M50
EVS87_013035	COG0739	heme binding
EVS87_013040	COG2894	cell division
EVS87_013045	COG0850	regulation of cytokinetic process
EVS87_013050	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EVS87_013055	COG1792	Involved in formation and maintenance of cell shape
EVS87_013060	COG1077	Cell shape determining protein MreB Mrl
EVS87_013065	COG2003	Belongs to the UPF0758 family
EVS87_013070	COG0424	maF-like protein
EVS87_013080	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EVS87_013085	COG0285	dihydrofolate synthase activity
EVS87_013090	COG0525	valine-tRNA ligase activity
EVS87_013100	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EVS87_013105	COG1388	LysM domain
EVS87_013110	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EVS87_013115	COG0113	porphobilinogen synthase activity
EVS87_013120	COG1587	Uroporphyrinogen-III synthase
EVS87_013125	COG0181	hydroxymethylbilane synthase activity
EVS87_013130	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EVS87_013135	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EVS87_013145	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EVS87_013150	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EVS87_013155	COG1067	ATP-dependent peptidase activity
EVS87_013155	COG0470	DNA polymerase III
EVS87_013160	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EVS87_013165	COG0544	peptidyl-prolyl cis-trans isomerase activity
EVS87_013170	COG0457	Tetratricopeptide repeat
EVS87_013170	COG1477	protein flavinylation
EVS87_013175	COG0066	3-isopropylmalate dehydratase activity
EVS87_013180	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EVS87_013185	COG0473	3-isopropylmalate dehydrogenase activity
EVS87_013190	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EVS87_013195	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EVS87_013200	COG0440	acetolactate synthase activity
EVS87_013205	COG0028	Belongs to the TPP enzyme family
EVS87_013210	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EVS87_013215	COG2706	6-phosphogluconolactonase activity
EVS87_013220	COG3339	Conserved Protein
EVS87_013225	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EVS87_013230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EVS87_013235	COG1696	Membrane protein involved in D-alanine export
EVS87_013240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EVS87_013310	COG0622	Phosphoesterase
EVS87_013315	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EVS87_013320	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EVS87_013325	COG5401	PFAM Sporulation and spore germination
EVS87_013330	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EVS87_013335	COG1846	Transcriptional regulator
EVS87_013340	COG2197	response regulator
EVS87_013345	COG2851	Citrate transporter
EVS87_013350	COG0583	DNA-binding transcription factor activity
EVS87_013355	COG2828	Protein conserved in bacteria
EVS87_013365	COG0824	Thioesterase
EVS87_013370	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EVS87_013375	COG1053	succinate dehydrogenase
EVS87_013380	COG2009	succinate dehydrogenase
EVS87_013385	COG1719	4-vinyl reductase, 4VR
EVS87_013395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EVS87_013400	COG0601	transmembrane transport
EVS87_013410	COG0527	aspartate kinase activity
EVS87_013415	COG0322	excinuclease ABC activity
EVS87_013420	COG3118	belongs to the thioredoxin family
EVS87_013425	COG3534	alpha-L-arabinofuranosidase
EVS87_013430	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EVS87_013435	COG2086	electron transfer activity
EVS87_013440	COG1024	Enoyl-CoA hydratase
EVS87_013445	COG1309	transcriptional regulator
EVS87_013450	COG0318	PFAM AMP-dependent synthetase and ligase
EVS87_013460	COG3766	membrane
EVS87_013465	COG1193	negative regulation of DNA recombination
EVS87_013470	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EVS87_013470	COG1796	DNA polymerase
EVS87_013475	COG1286	toxin biosynthetic process
EVS87_013480	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EVS87_013485	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EVS87_013490	COG0072	phenylalanine-tRNA ligase activity
EVS87_013490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EVS87_013495	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EVS87_013500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EVS87_013510	COG1966	Carbon starvation protein
EVS87_013515	COG1363	Peptidase, m42
EVS87_013525	COG3326	Membrane
EVS87_013530	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EVS87_013535	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EVS87_013540	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EVS87_013545	COG1346	cytolysis
EVS87_013555	COG3279	Response regulator of the LytR AlgR family
EVS87_013560	COG3275	phosphorelay sensor kinase activity
EVS87_013575	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EVS87_013585	COG0398	Pfam SNARE associated Golgi protein
EVS87_013590	COG1484	DNA-dependent DNA replication
EVS87_013595	COG3611	Membrane attachment protein
EVS87_013600	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EVS87_013610	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EVS87_013615	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EVS87_013620	COG0237	dephospho-CoA kinase activity
EVS87_013625	COG1971	Probably functions as a manganese efflux pump
EVS87_013630	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EVS87_013635	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EVS87_013635	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EVS87_013640	COG5002	protein histidine kinase activity
EVS87_013645	COG0745	RESPONSE REGULATOR receiver
EVS87_013650	COG0039	L-malate dehydrogenase activity
EVS87_013655	COG0538	isocitrate dehydrogenase activity
EVS87_013660	COG0372	Belongs to the citrate synthase family
EVS87_013665	COG2707	UPF0756 membrane protein
EVS87_013670	COG0628	permease
EVS87_013675	COG3030	protein affecting phage T7 exclusion by the F plasmid
EVS87_013685	COG0205	6-phosphofructokinase activity
EVS87_013690	COG0825	malonyl-CoA metabolic process
EVS87_013695	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EVS87_013700	COG0281	malic enzyme
EVS87_013705	COG0587	DNA-directed DNA polymerase activity
EVS87_013725	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EVS87_013740	COG4109	DRTGG domain
EVS87_013745	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EVS87_013750	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_013760	COG0165	Argininosuccinate lyase
EVS87_013765	COG0137	argininosuccinate synthase activity
EVS87_013770	COG0521	Mo-molybdopterin cofactor biosynthetic process
EVS87_013775	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EVS87_013780	COG0827	DNA restriction-modification system
EVS87_013785	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EVS87_013790	COG3874	Sporulation protein YtfJ
EVS87_013800	COG1714	RDD family
EVS87_013805	COG0616	signal peptide processing
EVS87_013810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EVS87_013820	COG3239	Fatty acid desaturase
EVS87_013825	COG4585	Histidine kinase
EVS87_013830	COG2197	response regulator
EVS87_013835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EVS87_013840	COG0745	RESPONSE REGULATOR receiver
EVS87_013845	COG2205	protein histidine kinase activity
EVS87_013850	COG0772	Belongs to the SEDS family
EVS87_013855	COG1695	Transcriptional regulator
EVS87_013860	COG1136	(ABC) transporter
EVS87_013865	COG0577	efflux transmembrane transporter activity
EVS87_013870	COG0402	S-adenosylhomocysteine deaminase activity
EVS87_013875	COG2249	NAD(P)H dehydrogenase (quinone) activity
EVS87_013890	COG1279	arginine transmembrane transporter activity
EVS87_013895	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EVS87_013905	COG0301	tRNA thio-modification
EVS87_013910	COG1104	cysteine desulfurase activity
EVS87_013915	COG1114	Component of the transport system for branched-chain amino acids
EVS87_013920	COG1114	Component of the transport system for branched-chain amino acids
EVS87_013925	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EVS87_013930	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EVS87_013935	COG1309	transcriptional regulator
EVS87_013940	COG1956	GAF domain-containing protein
EVS87_013945	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EVS87_013955	COG1335	isochorismatase
EVS87_013965	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EVS87_013970	COG2329	Antibiotic biosynthesis monooxygenase
EVS87_013975	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EVS87_013980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EVS87_013985	COG0454	-acetyltransferase
EVS87_013990	COG0517	IMP dehydrogenase activity
EVS87_013995	COG0123	including yeast histone deacetylase and acetoin utilization protein
EVS87_014000	COG1609	Transcriptional regulator
EVS87_014005	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EVS87_014005	COG1605	Chorismate mutase
EVS87_014010	COG3118	belongs to the thioredoxin family
EVS87_014015	COG4980	gas vesicle protein
EVS87_014020	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EVS87_014025	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EVS87_014030	COG1674	ftsk spoiiie
EVS87_014035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EVS87_014040	COG4848	Belongs to the UPF0354 family
EVS87_014045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EVS87_014060	COG1363	Peptidase, m42
EVS87_014065	COG5584	Small secreted protein
EVS87_014070	COG0281	malic enzyme
EVS87_014075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EVS87_014080	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EVS87_014090	COG0510	thiamine kinase activity
EVS87_014095	COG1597	lipid kinase activity
EVS87_014105	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EVS87_014110	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EVS87_014120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EVS87_014125	COG2252	PERMEase
EVS87_014130	COG1349	DNA-binding transcription factor activity
EVS87_014135	COG1187	pseudouridine synthase activity
EVS87_014140	COG2244	polysaccharide biosynthetic process
EVS87_014145	COG2081	HI0933 family
EVS87_014155	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EVS87_014160	COG3196	Protein conserved in bacteria
EVS87_014170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EVS87_014175	COG5578	integral membrane protein
EVS87_014180	COG0673	inositol 2-dehydrogenase activity
EVS87_014185	COG1653	transport
EVS87_014190	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EVS87_014195	COG4209	transmembrane transport
EVS87_014200	COG2207	Transcriptional regulator
EVS87_014205	COG1733	regulation of RNA biosynthetic process
EVS87_014210	COG2814	Major facilitator Superfamily
EVS87_014215	COG0656	L-ascorbic acid biosynthetic process
EVS87_014220	COG1653	transport
EVS87_014225	COG0395	ABC-type sugar transport system, permease component
EVS87_014230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EVS87_014235	COG1073	alpha beta
EVS87_014240	COG0495	leucyl-tRNA aminoacylation
EVS87_014250	COG2202	Pas domain
EVS87_014250	COG1366	Belongs to the anti-sigma-factor antagonist family
EVS87_014255	COG2433	Pfam Transposase IS66
EVS87_014260	COG0577	efflux transmembrane transporter activity
EVS87_014275	COG1131	(ABC) transporter
EVS87_014280	COG1725	Transcriptional regulator
EVS87_014300	COG1242	4 iron, 4 sulfur cluster binding
EVS87_014305	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EVS87_014310	COG4326	sporulation control protein
EVS87_014320	COG2267	carboxylic ester hydrolase activity
EVS87_014325	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EVS87_014330	COG0367	asparagine synthase
EVS87_014335	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EVS87_014340	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EVS87_014350	COG1506	peptidase
EVS87_014355	COG1233	COG1233 Phytoene dehydrogenase and related
EVS87_014375	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EVS87_014380	COG1116	anion transmembrane transporter activity
EVS87_014385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EVS87_014390	COG0494	nUDIX hydrolase
EVS87_014395	COG2310	stress, protein
EVS87_014410	COG4824	toxin secretion phage lysis holin
EVS87_014420	COG0783	Belongs to the Dps family
EVS87_014435	COG1854	S-ribosylhomocysteine lyase activity
EVS87_014440	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EVS87_014445	COG0288	reversible hydration of carbon dioxide
EVS87_014450	COG0803	Belongs to the bacterial solute-binding protein 9 family
EVS87_014450	COG3443	Belongs to the bacterial solute-binding protein 9 family
EVS87_014465	COG1271	oxidase subunit
EVS87_014470	COG1294	oxidase, subunit
EVS87_014485	COG4948	Mandelate Racemase Muconate Lactonizing
EVS87_014490	COG0318	PFAM AMP-dependent synthetase and ligase
EVS87_014495	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EVS87_014500	COG0596	Alpha beta hydrolase
EVS87_014505	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EVS87_014510	COG1169	isochorismate synthase
EVS87_014515	COG1575	Belongs to the MenA family. Type 1 subfamily
EVS87_014520	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EVS87_014650	COG3859	Proton-coupled thiamine transporter YuaJ
EVS87_014660	COG1247	-acetyltransferase
EVS87_014665	COG3339	Conserved Protein
EVS87_014670	COG0772	Belongs to the SEDS family
EVS87_014680	COG2268	Band 7 protein
EVS87_014685	COG1585	Membrane protein implicated in regulation of membrane protease activity
EVS87_014690	COG2318	DinB family
EVS87_014695	COG1454	alcohol dehydrogenase
EVS87_014705	COG1510	regulation of RNA biosynthetic process
EVS87_014720	COG5632	N-Acetylmuramoyl-L-alanine amidase
EVS87_014720	COG3409	Peptidoglycan-binding domain 1 protein
EVS87_014750	COG3778	Protein conserved in bacteria
EVS87_014755	COG3299	homolog of phage Mu protein gp47
EVS87_014760	COG3628	GPW Gp25 family protein
EVS87_014770	COG4193	domain, Protein
EVS87_014775	COG1652	LysM domain
EVS87_014780	COG5280	Phage tail tape measure protein TP901
EVS87_014780	COG3953	SLT domain
EVS87_014780	COG5280	Phage tail tape measure protein TP901
EVS87_014780	COG3953	SLT domain
EVS87_014835	COG4653	Phage capsid family
EVS87_014840	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EVS87_014845	COG5518	Phage portal protein
EVS87_014850	COG1783	phage Terminase large subunit
EVS87_014855	COG5484	DNA packaging
EVS87_014860	COG1595	DNA-templated transcription, initiation
EVS87_014870	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
EVS87_014885	COG1396	sequence-specific DNA binding
EVS87_014895	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EVS87_014910	COG0628	permease
EVS87_014920	COG0673	inositol 2-dehydrogenase activity
EVS87_014925	COG0693	protein deglycase activity
EVS87_014930	COG0840	transmembrane signaling receptor activity
EVS87_014935	COG0840	transmembrane signaling receptor activity
EVS87_014940	COG0840	transmembrane signaling receptor activity
EVS87_014945	COG0840	transmembrane signaling receptor activity
EVS87_014960	COG2070	2-Nitropropane dioxygenase
EVS87_014965	COG0432	Pfam Uncharacterised protein family UPF0047
EVS87_014970	COG1253	flavin adenine dinucleotide binding
EVS87_014975	COG2738	Putative neutral zinc metallopeptidase
EVS87_014985	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EVS87_015000	COG0166	Belongs to the GPI family
EVS87_015005	COG1979	alcohol dehydrogenase
EVS87_015010	COG1979	alcohol dehydrogenase
EVS87_015015	COG2155	Conserved Protein
EVS87_015020	COG1098	S1 RNA binding domain
EVS87_015025	COG0436	Aminotransferase
EVS87_015030	COG1522	sequence-specific DNA binding
EVS87_015035	COG2267	carboxylic ester hydrolase activity
EVS87_015045	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EVS87_015050	COG2205	protein histidine kinase activity
EVS87_015060	COG5018	Exonuclease
EVS87_015065	COG2814	Major facilitator Superfamily
EVS87_015070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EVS87_015075	COG3011	Protein conserved in bacteria
EVS87_015085	COG3290	protein histidine kinase activity
EVS87_015090	COG4565	transcriptional regulatory protein
EVS87_015115	COG3493	citrate carrier protein
EVS87_015130	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EVS87_015130	COG2111	Na H antiporter
EVS87_015135	COG2111	Na H antiporter
EVS87_015140	COG1006	Multisubunit Na H antiporter MnhC subunit
EVS87_015145	COG0651	ATP synthesis coupled electron transport
EVS87_015150	COG1863	multisubunit Na H antiporter MnhE subunit
EVS87_015155	COG2212	antiporter activity
EVS87_015160	COG1320	monovalent cation:proton antiporter activity
EVS87_015165	COG2050	protein possibly involved in aromatic compounds catabolism
EVS87_015170	COG2197	response regulator
EVS87_015175	COG4585	Histidine kinase
EVS87_015185	COG0142	geranyltranstransferase activity
EVS87_015200	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EVS87_015205	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EVS87_015210	COG1335	isochorismatase
EVS87_015215	COG5506	Protein of unknown function (DUF1694)
EVS87_015235	COG0628	permease
EVS87_015250	COG1418	mRNA catabolic process
EVS87_015255	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_015265	COG1511	domain protein
EVS87_015270	COG0433	COG0433 Predicted ATPase
EVS87_015270	COG1674	ftsk spoiiie
EVS87_015275	COG4499	WXG100 protein secretion system (Wss), protein YukC
EVS87_015280	COG5417	Belongs to the EsaB family
EVS87_015285	COG4842	Belongs to the WXG100 family
EVS87_015290	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EVS87_015290	COG2508	Transcriptional regulator
EVS87_015295	COG0686	Belongs to the AlaDH PNT family
EVS87_015300	COG1268	BioY protein
EVS87_015305	COG2056	Na+-H+ antiporter family
EVS87_015310	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EVS87_015315	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EVS87_015320	COG3584	3D domain protein
EVS87_015330	COG1252	NADH dehydrogenase
EVS87_015335	COG0492	ferredoxin-NADP+ reductase activity
EVS87_015350	COG0789	Transcriptional regulator
EVS87_015355	COG5504	Zn-dependent protease
EVS87_015360	COG0316	Belongs to the HesB IscA family
EVS87_015365	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EVS87_015370	COG4844	belongs to the
EVS87_015375	COG1252	NADH dehydrogenase
EVS87_015385	COG4837	Protein of unknown function (DUF1462)
EVS87_015390	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EVS87_015395	COG0823	Involved in the tonB-independent uptake of proteins
EVS87_015395	COG4946	Tricorn protease homolog
EVS87_015395	COG1506	peptidase
EVS87_015400	COG0083	homoserine kinase activity
EVS87_015405	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EVS87_015410	COG0460	homoserine dehydrogenase
EVS87_015415	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EVS87_015420	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EVS87_015425	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EVS87_015430	COG0647	UMP catabolic process
EVS87_015435	COG2445	Protein of unknown function DUF86
EVS87_015440	COG4470	Protein conserved in bacteria
EVS87_015450	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EVS87_015455	COG0739	heme binding
EVS87_015475	COG3377	Domain of unknown function (DUF1805)
EVS87_015480	COG0737	Belongs to the 5'-nucleotidase family
EVS87_015485	COG1801	Protein of unknown function DUF72
EVS87_015490	COG2508	Transcriptional regulator
EVS87_015495	COG2140	Oxalate decarboxylase
EVS87_015500	COG2814	Major facilitator Superfamily
EVS87_015505	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EVS87_015510	COG2356	endonuclease I
EVS87_015520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EVS87_015525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EVS87_015530	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EVS87_015550	COG0642	Histidine kinase
EVS87_015550	COG5002	protein histidine kinase activity
EVS87_015555	COG0745	RESPONSE REGULATOR receiver
EVS87_015560	COG2311	Membrane
EVS87_015570	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EVS87_015575	COG1090	epimerase
EVS87_015585	COG0719	Fe-S assembly protein
EVS87_015590	COG0822	iron-sulfur transferase activity
EVS87_015595	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EVS87_015600	COG0719	Fe-S assembly protein
EVS87_015605	COG0396	ATPase activity
EVS87_015610	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EVS87_015615	COG1464	Belongs to the NlpA lipoprotein family
EVS87_015620	COG2011	ABC-type metal ion transport system permease component
EVS87_015625	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EVS87_015635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EVS87_015640	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EVS87_015650	COG0509	glycine decarboxylation via glycine cleavage system
EVS87_015655	COG1393	Belongs to the ArsC family
EVS87_015660	COG1960	acyl-CoA dehydrogenase activity
EVS87_015665	COG0183	Belongs to the thiolase family
EVS87_015670	COG1250	3-hydroxyacyl-CoA dehydrogenase
EVS87_015670	COG1024	Enoyl-CoA hydratase
EVS87_015685	COG5577	PFAM Coat F domain
EVS87_015695	COG1120	ATPase activity
EVS87_015705	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_015715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EVS87_015720	COG0745	RESPONSE REGULATOR receiver
EVS87_015725	COG2205	protein histidine kinase activity
EVS87_015725	COG2770	Histidine kinase
EVS87_015730	COG1309	transcriptional regulator
EVS87_015735	COG0114	fumarate hydratase activity
EVS87_015745	COG0697	spore germination
EVS87_015750	COG0814	amino acid
EVS87_015765	COG2197	response regulator
EVS87_015770	COG4585	Histidine kinase
EVS87_015775	COG4758	membrane
EVS87_015785	COG1842	Phage shock protein A
EVS87_015790	COG4758	membrane
EVS87_015795	COG2096	Adenosyltransferase
EVS87_015800	COG1120	ATPase activity
EVS87_015805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EVS87_015810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EVS87_015820	COG2721	sulfolactate sulfo-lyase activity
EVS87_015825	COG0246	Mannitol dehydrogenase
EVS87_015830	COG1609	Transcriptional regulator
EVS87_015835	COG1904	glucuronate isomerase
EVS87_015840	COG2205	protein histidine kinase activity
EVS87_015845	COG0745	RESPONSE REGULATOR receiver
EVS87_015850	COG1120	ATPase activity
EVS87_015855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EVS87_015860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EVS87_015865	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EVS87_015870	COG0531	amino acid
EVS87_015890	COG1988	membrane-bound metal-dependent
EVS87_015895	COG1368	sulfuric ester hydrolase activity
EVS87_015900	COG0725	ABC transporter, periplasmic molybdate-binding protein
EVS87_015905	COG4149	molybdate abc transporter
EVS87_015915	COG0656	L-ascorbic acid biosynthetic process
EVS87_015920	COG1940	carbohydrate kinase activity
EVS87_015925	COG0025	NhaP-type Na H and K H
EVS87_015930	COG2860	membrane
EVS87_015935	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EVS87_015940	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EVS87_015945	COG2217	Heavy metal translocating P-type atpase
EVS87_015950	COG1121	(ABC) transporter
EVS87_015955	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EVS87_015960	COG0803	Belongs to the bacterial solute-binding protein 9 family
EVS87_015970	COG3226	Transcriptional regulator
EVS87_015975	COG0784	Response regulator, receiver
EVS87_015980	COG4191	Histidine kinase
EVS87_015985	COG1027	Aspartate ammonia-lyase
EVS87_015995	COG2217	Heavy metal translocating P-type atpase
EVS87_016000	COG2608	mercury ion transmembrane transporter activity
EVS87_016005	COG1937	Protein conserved in bacteria
EVS87_016015	COG0745	RESPONSE REGULATOR receiver
EVS87_016015	COG3706	GGDEF domain
EVS87_016035	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EVS87_016040	COG0557	exoribonuclease II activity
EVS87_016045	COG1647	Serine aminopeptidase, S33
EVS87_016050	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EVS87_016055	COG2002	toxin-antitoxin pair type II binding
EVS87_016060	COG1476	TRANSCRIPTIONal
EVS87_016065	COG1396	sequence-specific DNA binding
EVS87_016070	COG1396	sequence-specific DNA binding
EVS87_016075	COG1733	regulation of RNA biosynthetic process
EVS87_016080	COG1174	glycine betaine transport
EVS87_016085	COG1732	Glycine betaine
EVS87_016090	COG1174	glycine betaine transport
EVS87_016095	COG0517	IMP dehydrogenase activity
EVS87_016095	COG1125	glycine betaine transport
EVS87_016100	COG1510	regulation of RNA biosynthetic process
EVS87_016105	COG2095	MarC family integral membrane protein
EVS87_016115	COG0456	acetyltransferase
EVS87_016135	COG1131	(ABC) transporter
EVS87_016145	COG0148	phosphopyruvate hydratase activity
EVS87_016150	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EVS87_016155	COG0149	triose-phosphate isomerase activity
EVS87_016160	COG0126	phosphoglycerate kinase activity
EVS87_016165	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EVS87_016170	COG2390	Transcriptional regulator
EVS87_016175	COG0833	amino acid
EVS87_016180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EVS87_016185	COG3829	transcription factor binding
EVS87_016190	COG2186	Transcriptional regulator
EVS87_016195	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EVS87_016205	COG0534	Mate efflux family protein
EVS87_016210	COG4608	Belongs to the ABC transporter superfamily
EVS87_016215	COG0444	Belongs to the ABC transporter superfamily
EVS87_016220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EVS87_016225	COG0601	transmembrane transport
EVS87_016230	COG0747	negative chemotaxis
EVS87_016235	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EVS87_016240	COG0110	maltose O-acetyltransferase activity
EVS87_016245	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EVS87_016250	COG2244	polysaccharide biosynthetic process
EVS87_016255	COG5039	Polysaccharide pyruvyl transferase
EVS87_016260	COG1216	Glycosyl transferase, family 2
EVS87_016270	COG0438	transferase activity, transferring glycosyl groups
EVS87_016275	COG1215	transferase activity, transferring glycosyl groups
EVS87_016280	COG0438	transferase activity, transferring glycosyl groups
EVS87_016285	COG1086	Polysaccharide biosynthesis protein
EVS87_016290	COG0489	protein tyrosine kinase activity
EVS87_016295	COG3944	biosynthesis protein
EVS87_016300	COG1396	sequence-specific DNA binding
EVS87_016310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EVS87_016315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EVS87_016320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EVS87_016325	COG0726	polysaccharide deacetylase
EVS87_016335	COG1819	glycosyl
EVS87_016360	COG3177	Filamentation induced by cAMP protein fic
EVS87_016380	COG0740	serine-type endopeptidase activity
EVS87_016385	COG1611	Belongs to the LOG family
EVS87_016390	COG1694	Mazg nucleotide pyrophosphohydrolase
EVS87_016395	COG0659	secondary active sulfate transmembrane transporter activity
EVS87_016400	COG0288	reversible hydration of carbon dioxide
EVS87_016405	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EVS87_016415	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EVS87_016420	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EVS87_016425	COG1481	regulation of sporulation
EVS87_016430	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EVS87_016435	COG1660	Displays ATPase and GTPase activities
EVS87_016440	COG1051	belongs to the nudix hydrolase family
EVS87_016445	COG0492	ferredoxin-NADP+ reductase activity
EVS87_016450	COG0791	NLP P60 protein
EVS87_016450	COG3883	PFAM NLP P60 protein
EVS87_016455	COG0457	Tetratricopeptide repeat
EVS87_016460	COG0140	phosphoribosyl-ATP diphosphatase activity
EVS87_016460	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EVS87_016465	COG0107	imidazoleglycerol-phosphate synthase activity
EVS87_016470	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EVS87_016475	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EVS87_016480	COG0131	Imidazoleglycerol-phosphate dehydratase
EVS87_016485	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EVS87_016490	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EVS87_016495	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EVS87_016500	COG4990	cell redox homeostasis
EVS87_016510	COG2910	NAD(P)H-binding
EVS87_016515	COG1959	2 iron, 2 sulfur cluster binding
EVS87_016520	COG0110	maltose O-acetyltransferase activity
EVS87_016525	COG0546	phosphoglycolate phosphatase activity
EVS87_016530	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EVS87_016535	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EVS87_016540	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EVS87_016545	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EVS87_016550	COG0363	glucosamine-6-phosphate deaminase activity
EVS87_016560	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EVS87_016565	COG1950	PFAM Membrane protein of
EVS87_016570	COG1983	PspC domain protein
EVS87_016575	COG3595	metallopeptidase activity
EVS87_016595	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EVS87_016605	COG4897	Protein conserved in bacteria
EVS87_016610	COG3848	Pyruvate phosphate dikinase
EVS87_016610	COG0574	Belongs to the PEP-utilizing enzyme family
EVS87_016615	COG1309	transcriptional regulator
EVS87_016620	COG2814	Major facilitator Superfamily
EVS87_016630	COG0745	RESPONSE REGULATOR receiver
EVS87_016635	COG5002	protein histidine kinase activity
EVS87_016640	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EVS87_016645	COG0463	Glycosyl transferase, family 2
EVS87_016650	COG1113	amino acid transport
EVS87_016655	COG0778	Nitroreductase
EVS87_016660	COG1733	regulation of RNA biosynthetic process
EVS87_016665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EVS87_016675	COG3409	Peptidoglycan-binding domain 1 protein
EVS87_016675	COG0793	Belongs to the peptidase S41A family
EVS87_016680	COG0730	response to heat
EVS87_016685	COG0791	NLP P60 protein
EVS87_016685	COG3883	PFAM NLP P60 protein
EVS87_016690	COG2177	Part of the ABC transporter FtsEX involved in
EVS87_016695	COG2884	Cell division ATP-binding protein ftsE
EVS87_016700	COG2010	Cytochrome c
EVS87_016705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EVS87_016725	COG0653	protein targeting
EVS87_016730	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EVS87_016735	COG0840	transmembrane signaling receptor activity
EVS87_016750	COG1516	flagellar protein fliS
EVS87_016755	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EVS87_016760	COG1334	flagellar protein FlaG
EVS87_016765	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EVS87_016770	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
EVS87_016780	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EVS87_016785	COG1256	bacterial-type flagellum assembly
EVS87_016785	COG4786	Flagellar basal body rod
EVS87_016790	COG3418	PFAM FlgN family protein
EVS87_016805	COG1040	competence protein
EVS87_016815	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EVS87_016820	COG1307	EDD domain protein, DegV family
EVS87_016825	COG2197	response regulator
EVS87_016830	COG4585	Histidine kinase
EVS87_016835	COG1739	Uncharacterized protein family UPF0029
EVS87_016840	COG1316	TRANSCRIPTIONal
EVS87_016845	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EVS87_016850	COG0438	transferase activity, transferring glycosyl groups
EVS87_016855	COG1215	transferase activity, transferring glycosyl groups
EVS87_016860	COG3206	protein involved in exopolysaccharide biosynthesis
EVS87_016865	COG3307	-O-antigen
EVS87_016870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EVS87_016875	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EVS87_016880	COG0438	transferase activity, transferring glycosyl groups
EVS87_016880	COG0297	glycogen (starch) synthase activity
EVS87_016885	COG2244	polysaccharide biosynthetic process
EVS87_016900	COG0860	N-Acetylmuramoyl-L-alanine amidase
EVS87_016900	COG2247	cell wall binding repeat
EVS87_016905	COG2247	cell wall binding repeat
EVS87_016905	COG0860	N-Acetylmuramoyl-L-alanine amidase
EVS87_016910	COG2385	sporulation resulting in formation of a cellular spore
EVS87_016910	COG2247	cell wall binding repeat
EVS87_016920	COG1316	TRANSCRIPTIONal
EVS87_016945	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EVS87_016950	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EVS87_016955	COG1134	teichoic acid transport
EVS87_016960	COG1682	transport, permease protein
EVS87_016965	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EVS87_016965	COG1215	transferase activity, transferring glycosyl groups
EVS87_016970	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EVS87_016980	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EVS87_016985	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EVS87_016990	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EVS87_016995	COG4193	domain, Protein
EVS87_017000	COG1482	cell wall glycoprotein biosynthetic process
EVS87_017010	COG1175	transmembrane transport
EVS87_017015	COG1653	transport
EVS87_017020	COG2197	response regulator
EVS87_017025	COG2972	Histidine kinase
EVS87_017035	COG0454	-acetyltransferase
EVS87_017040	COG0800	Aldolase
EVS87_017045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EVS87_017050	COG1609	Transcriptional regulator
EVS87_017055	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
EVS87_017060	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_017065	COG0697	spore germination
EVS87_017070	COG0814	amino acid
EVS87_017090	COG2814	Major facilitator Superfamily
EVS87_017095	COG1316	TRANSCRIPTIONal
EVS87_017100	COG0561	phosphatase activity
EVS87_017105	COG0791	NLP P60 protein
EVS87_017110	COG2843	Capsule synthesis protein
EVS87_017120	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EVS87_017125	COG0697	spore germination
EVS87_017140	COG1609	Transcriptional regulator
EVS87_017145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EVS87_017150	COG1869	D-ribose catabolic process
EVS87_017155	COG1129	ABC transporter
EVS87_017160	COG1172	Belongs to the binding-protein-dependent transport system permease family
EVS87_017165	COG1879	ABC-type sugar transport system periplasmic component
EVS87_017170	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EVS87_017175	COG0583	DNA-binding transcription factor activity
EVS87_017180	COG0028	Belongs to the TPP enzyme family
EVS87_017185	COG3527	Alpha-acetolactate decarboxylase
EVS87_017190	COG1522	sequence-specific DNA binding
EVS87_017195	COG2059	Chromate
EVS87_017200	COG2059	Chromate
EVS87_017205	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EVS87_017210	COG4715	Zinc finger, swim domain protein
EVS87_017215	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EVS87_017220	COG2202	Pas domain
EVS87_017220	COG1366	Belongs to the anti-sigma-factor antagonist family
EVS87_017225	COG0561	phosphatase activity
EVS87_017240	COG1970	mechanosensitive ion channel activity
EVS87_017245	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EVS87_017250	COG0457	Tetratricopeptide repeat
EVS87_017255	COG4786	Flagellar basal body rod
EVS87_017260	COG4786	Flagellar basal body rod
EVS87_017265	COG1077	Cell shape determining protein MreB Mrl
EVS87_017270	COG1609	Transcriptional regulator
EVS87_017275	COG1846	Transcriptional regulator
EVS87_017280	COG2814	Major facilitator Superfamily
EVS87_017285	COG0671	phosphoesterase, PA-phosphatase related
EVS87_017290	COG0477	Major facilitator Superfamily
EVS87_017295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EVS87_017300	COG0765	amino acid transport
EVS87_017305	COG1126	abc transporter atp-binding protein
EVS87_017310	COG0004	ammonium transporteR
EVS87_017315	COG0347	Belongs to the P(II) protein family
EVS87_017320	COG0739	heme binding
EVS87_017325	COG1247	-acetyltransferase
EVS87_017370	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EVS87_017375	COG0523	cobalamin synthesis protein
EVS87_017380	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EVS87_017385	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EVS87_017390	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EVS87_017405	COG2304	oxidoreductase activity
EVS87_017410	COG2304	oxidoreductase activity
EVS87_017415	COG2385	sporulation resulting in formation of a cellular spore
EVS87_017420	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EVS87_017430	COG4836	Membrane
EVS87_017440	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EVS87_017445	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EVS87_017450	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EVS87_017455	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EVS87_017460	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EVS87_017465	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EVS87_017470	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EVS87_017475	COG0356	it plays a direct role in the translocation of protons across the membrane
EVS87_017485	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EVS87_017490	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EVS87_017495	COG4475	Protein of unknown function (DUF436)
EVS87_017500	COG0698	ribose 5-phosphate isomerase
EVS87_017505	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EVS87_017510	COG1971	Probably functions as a manganese efflux pump
EVS87_017515	COG0009	L-threonylcarbamoyladenylate synthase
EVS87_017520	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EVS87_017535	COG2890	protein-(glutamine-N5) methyltransferase activity
EVS87_017540	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EVS87_017550	COG0679	Auxin Efflux Carrier
EVS87_017555	COG0281	malic enzyme
EVS87_017560	COG1435	thymidine kinase activity
EVS87_017565	COG0254	rRNA binding
EVS87_017570	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EVS87_017575	COG1494	fructose-1,6-bisphosphatase
EVS87_017580	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EVS87_017585	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EVS87_017590	COG0191	fructose-bisphosphate aldolase activity
EVS87_017595	COG2204	response regulator
EVS87_017600	COG4821	SIS domain
EVS87_017605	COG0504	CTP synthase activity
EVS87_017610	COG3343	RNA polymerase activity
EVS87_017625	COG1960	acyl-CoA dehydrogenase activity
EVS87_017630	COG1960	acyl-CoA dehydrogenase activity
EVS87_017635	COG1250	3-hydroxyacyl-CoA dehydrogenase
EVS87_017640	COG0183	Belongs to the thiolase family
EVS87_017645	COG0247	lactate metabolic process
EVS87_017645	COG2181	nitrate reductase activity
EVS87_017650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EVS87_017655	COG4294	response to UV
EVS87_017665	COG1619	proteins homologs of microcin C7 resistance protein MccF
EVS87_017675	COG1132	(ABC) transporter
EVS87_017680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EVS87_017685	COG1619	proteins homologs of microcin C7 resistance protein MccF
EVS87_017695	COG0018	arginyl-trna synthetase
EVS87_017700	COG4506	Protein conserved in bacteria
EVS87_017710	COG0010	Belongs to the arginase family
EVS87_017715	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EVS87_017720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EVS87_017730	COG1994	Peptidase M50
EVS87_017735	COG1942	4-Oxalocrotonate Tautomerase
EVS87_017745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EVS87_017750	COG0583	DNA-binding transcription factor activity
EVS87_017755	COG0431	NADPH-dependent FMN reductase
EVS87_017760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EVS87_017765	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EVS87_017770	COG0454	-acetyltransferase
EVS87_017775	COG0765	amino acid transport
EVS87_017785	COG0765	amino acid transport
EVS87_017790	COG1126	abc transporter atp-binding protein
EVS87_017795	COG3465	dGTPase activity
EVS87_017800	COG1078	dGTPase activity
EVS87_017805	COG4844	belongs to the
EVS87_017850	COG5444	nuclease activity
EVS87_017880	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EVS87_017890	COG0280	phosphate acetyltransferase
EVS87_017900	COG2814	Major facilitator Superfamily
EVS87_017905	COG1522	sequence-specific DNA binding
EVS87_017910	COG2814	Major facilitator Superfamily
EVS87_017915	COG0077	Prephenate dehydratase
EVS87_017920	COG1917	Cupin 2, conserved barrel domain protein
EVS87_017925	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_017930	COG0151	Belongs to the GarS family
EVS87_017935	COG0436	Aminotransferase
EVS87_017940	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_017945	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
EVS87_017950	COG1091	dTDP-4-dehydrorhamnose reductase activity
EVS87_017955	COG1088	dTDP-glucose 4,6-dehydratase activity
EVS87_017960	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EVS87_017965	COG3980	spore coat polysaccharide biosynthesis protein
EVS87_017970	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
EVS87_017975	COG2089	acid synthase
EVS87_017980	COG0456	acetyltransferase
EVS87_017985	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EVS87_017990	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EVS87_017995	COG0463	Glycosyl transferase, family 2
EVS87_018015	COG2363	Small membrane protein
EVS87_018020	COG2233	PERMEase
EVS87_018030	COG1012	belongs to the aldehyde dehydrogenase family
EVS87_018035	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EVS87_018040	COG1216	Glycosyl transferase, family 2
EVS87_018050	COG0351	phosphomethylpyrimidine kinase
EVS87_018065	COG1621	beta-fructofuranosidase activity
EVS87_018070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EVS87_018070	COG1263	PTS System
EVS87_018075	COG3711	transcriptional antiterminator
EVS87_018085	COG1404	Belongs to the peptidase S8 family
EVS87_018095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EVS87_018100	COG0778	Nitroreductase
EVS87_018105	COG0772	Belongs to the SEDS family
EVS87_018115	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EVS87_018120	COG1845	cytochrome c oxidase, subunit III
EVS87_018125	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EVS87_018130	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EVS87_018140	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EVS87_018145	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EVS87_018150	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EVS87_018165	COG2246	polysaccharide biosynthetic process
EVS87_018185	COG3162	membrane
EVS87_018190	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EVS87_018200	COG0352	thiamine-phosphate diphosphorylase activity
EVS87_018205	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EVS87_018210	COG0583	DNA-binding transcription factor activity
EVS87_018215	COG1380	Effector of murein hydrolase LrgA
EVS87_018220	COG1346	cytolysis
EVS87_018225	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EVS87_018230	COG0346	lactoylglutathione lyase activity
EVS87_018240	COG0765	amino acid transport
EVS87_018245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EVS87_018255	COG0457	Tetratricopeptide repeat
EVS87_018260	COG2357	RelA SpoT domain protein
EVS87_018265	COG1172	Belongs to the binding-protein-dependent transport system permease family
EVS87_018270	COG1129	ABC transporter
EVS87_018280	COG3420	alginic acid biosynthetic process
EVS87_018285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EVS87_018300	COG1486	melibiose metabolic process
EVS87_018305	COG1447	Phosphotransferase system cellobiose-specific component IIA
EVS87_018310	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EVS87_018315	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EVS87_018320	COG3711	transcriptional antiterminator
EVS87_018320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EVS87_018335	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EVS87_018350	COG1595	DNA-templated transcription, initiation
EVS87_018355	COG3866	Pectate lyase
EVS87_018360	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EVS87_018365	COG4988	ABC transporter
EVS87_018370	COG1294	oxidase, subunit
EVS87_018375	COG1271	oxidase subunit
EVS87_018385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EVS87_018390	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EVS87_018395	COG4509	Sortase family
EVS87_018420	COG5386	Cell surface protein
EVS87_018425	COG5386	Cell surface protein
EVS87_018430	COG1733	regulation of RNA biosynthetic process
EVS87_018435	COG2514	catechol 2,3-dioxygenase activity
EVS87_018440	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EVS87_018440	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EVS87_018445	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EVS87_018445	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EVS87_018455	COG0726	polysaccharide deacetylase
EVS87_018460	COG1447	Phosphotransferase system cellobiose-specific component IIA
EVS87_018465	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EVS87_018470	COG2723	6-phospho-beta-galactosidase activity
EVS87_018475	COG1312	Catalyzes the dehydration of D-mannonate
EVS87_018480	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EVS87_018485	COG3711	transcriptional antiterminator
EVS87_018485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EVS87_018515	COG1027	Aspartate ammonia-lyase
EVS87_018520	COG0252	asparaginase activity
EVS87_018525	COG1396	sequence-specific DNA binding
EVS87_018550	COG4842	Belongs to the WXG100 family
EVS87_018555	COG2195	Cleaves the N-terminal amino acid of tripeptides
EVS87_018570	COG1737	Transcriptional regulator
EVS87_018575	COG2084	Dehydrogenase
EVS87_018585	COG2610	gluconate transmembrane transporter activity
EVS87_018590	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EVS87_018600	COG1136	(ABC) transporter
EVS87_018620	COG2723	6-phospho-beta-galactosidase activity
EVS87_018625	COG1263	PTS System
EVS87_018625	COG2190	(PTS) system
EVS87_018625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EVS87_018630	COG3711	transcriptional antiterminator
EVS87_018635	COG3878	Protein conserved in bacteria
EVS87_018645	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EVS87_018650	COG1122	ATPase activity
EVS87_018655	COG4721	ABC-type cobalt transport system, permease component
EVS87_018660	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EVS87_018685	COG4412	M6 family metalloprotease domain protein
EVS87_018685	COG3291	Pkd domain containing protein
EVS87_018690	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EVS87_018695	COG0778	Nitroreductase
EVS87_018700	COG1846	Transcriptional regulator
EVS87_018705	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EVS87_018710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EVS87_018715	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EVS87_018720	COG2390	Transcriptional regulator
EVS87_018730	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EVS87_018730	COG2755	lipolytic protein G-D-S-L family
EVS87_018735	COG0477	Major facilitator Superfamily
EVS87_018740	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EVS87_018745	COG2226	methyltransferase
EVS87_018755	COG0561	phosphatase activity
EVS87_018760	COG0789	Transcriptional regulator
EVS87_018765	COG0673	inositol 2-dehydrogenase activity
EVS87_018770	COG0840	transmembrane signaling receptor activity
EVS87_018775	COG1113	amino acid transport
EVS87_018780	COG4335	DNA alkylation repair
EVS87_018790	COG1070	Carbohydrate kinase
EVS87_018795	COG1737	Transcriptional regulator
EVS87_018835	COG0583	DNA-binding transcription factor activity
EVS87_018840	COG1609	Transcriptional regulator
EVS87_018845	COG2182	Extracellular solute-binding protein
EVS87_018850	COG1175	transmembrane transport
EVS87_018855	COG3833	ABC-type maltose transport systems, permease component
EVS87_018865	COG1874	Beta-galactosidase
EVS87_018870	COG2851	Citrate transporter
EVS87_018880	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EVS87_018885	COG1131	(ABC) transporter
EVS87_018890	COG2824	Alkylphosphonate utilization operon protein PhnA
EVS87_018895	COG1929	Belongs to the glycerate kinase type-1 family
EVS87_018900	COG2610	gluconate transmembrane transporter activity
EVS87_018905	COG3835	regulator
EVS87_018910	COG1309	transcriptional regulator
EVS87_018915	COG2814	Major facilitator Superfamily
EVS87_018925	COG1136	(ABC) transporter
EVS87_018940	COG3711	transcriptional antiterminator
EVS87_018945	COG2723	6-phospho-beta-galactosidase activity
EVS87_018950	COG1263	PTS System
EVS87_018950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EVS87_018950	COG2190	(PTS) system
EVS87_018975	COG0494	nUDIX hydrolase
EVS87_018990	COG1113	amino acid transport
EVS87_019000	COG2814	Major facilitator Superfamily
EVS87_019005	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EVS87_019010	COG2814	Major facilitator Superfamily
EVS87_019040	COG5444	nuclease activity
EVS87_019050	COG2723	6-phospho-beta-galactosidase activity
EVS87_019060	COG2188	Transcriptional regulator
EVS87_019070	COG0384	phenazine biosynthesis protein PhzF
EVS87_019075	COG0583	DNA-binding transcription factor activity
EVS87_019110	COG5002	protein histidine kinase activity
EVS87_019110	COG3850	Histidine kinase
EVS87_019120	COG2409	Drug exporters of the RND superfamily
EVS87_019125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EVS87_019150	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EVS87_019155	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EVS87_019165	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EVS87_019175	COG4720	Psort location CytoplasmicMembrane, score
EVS87_019195	COG0456	acetyltransferase
EVS87_019200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EVS87_019205	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EVS87_019210	COG4853	Protein conserved in bacteria
EVS87_019215	COG4863	YycH protein
EVS87_019220	COG5002	protein histidine kinase activity
EVS87_019225	COG0745	RESPONSE REGULATOR receiver
EVS87_019250	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EVS87_019260	COG2311	Membrane
EVS87_019265	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EVS87_019270	COG1309	transcriptional regulator
EVS87_019275	COG2124	cytochrome p450
EVS87_019280	COG0346	lactoylglutathione lyase activity
EVS87_019285	COG0305	Participates in initiation and elongation during chromosome replication
EVS87_019300	COG2819	hydrolase of the alpha beta superfamily
EVS87_019305	COG1028	Short-chain dehydrogenase reductase Sdr
EVS87_019310	COG1169	isochorismate synthase
EVS87_019315	COG1021	2,3-dihydroxybenzoate-AMP ligase
EVS87_019320	COG3433	isochorismatase activity
EVS87_019320	COG1535	isochorismatase
EVS87_019325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EVS87_019330	COG3251	PFAM MbtH domain protein
EVS87_019335	COG2207	Transcriptional regulator
EVS87_019335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EVS87_019340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EVS87_019345	COG2819	hydrolase of the alpha beta superfamily
EVS87_019350	COG3093	addiction module antidote protein HigA
EVS87_019355	COG2807	transmembrane transport
EVS87_019360	COG0359	binds to the 23S rRNA
EVS87_019365	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EVS87_019370	COG4241	membrane
EVS87_019375	COG1227	inorganic diphosphatase activity
EVS87_019385	COG1595	DNA-templated transcription, initiation
EVS87_019400	COG0655	NAD(P)H dehydrogenase (quinone) activity
EVS87_019405	COG0400	carboxylic ester hydrolase activity
EVS87_019410	COG0346	lactoylglutathione lyase activity
EVS87_019415	COG1174	glycine betaine transport
EVS87_019420	COG0517	IMP dehydrogenase activity
EVS87_019420	COG1125	glycine betaine transport
EVS87_019425	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EVS87_019430	COG0629	single-stranded DNA binding
EVS87_019435	COG0360	Binds together with S18 to 16S ribosomal RNA
EVS87_019440	COG0012	GTP binding
EVS87_019445	COG4481	Protein conserved in bacteria
EVS87_019460	COG3949	Membrane
EVS87_019470	COG1475	DNA binding
EVS87_019475	COG1192	Involved in chromosome partitioning
EVS87_019485	COG1475	DNA binding
EVS87_019490	COG0357	Ribosomal RNA small subunit methyltransferase G
EVS87_019495	COG0445	tRNA wobble uridine modification
EVS87_019500	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EVS87_019505	COG1847	R3H domain protein
EVS87_019510	COG0706	membrane insertase activity
EVS87_019515	COG0594	ribonuclease P activity
EVS87_019520	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EVS87_019525	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EVS87_019530	COG0592	DNA-directed DNA polymerase activity
EVS87_019535	COG2501	S4 domain
EVS87_019540	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EVS87_019550	COG0187	DNA topoisomerase II activity
EVS87_019555	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EVS87_019590	COG0516	GMP reductase activity
EVS87_019590	COG0517	IMP dehydrogenase activity
EVS87_019595	COG1686	Belongs to the peptidase S11 family
EVS87_019600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EVS87_019605	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EVS87_019610	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EVS87_019615	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EVS87_019620	COG0840	transmembrane signaling receptor activity
EVS87_019630	COG1428	Deoxynucleoside kinase
EVS87_019635	COG1428	Deoxynucleoside kinase
EVS87_019640	COG1388	LysM domain
EVS87_019640	COG3858	chitin binding
EVS87_019645	COG1335	isochorismatase
EVS87_019650	COG0590	tRNA wobble adenosine to inosine editing
EVS87_019660	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EVS87_019665	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EVS87_019670	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EVS87_019715	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
EVS87_019720	COG3853	Toxic anion resistance protein (TelA)
EVS87_019725	COG1982	Orn Lys Arg decarboxylase major
EVS87_019730	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EVS87_019735	COG3870	Protein conserved in bacteria
EVS87_019740	COG1728	Protein conserved in bacteria
EVS87_019745	COG0470	DNA polymerase III
EVS87_019750	COG1774	PSP1 C-terminal conserved region
EVS87_019755	COG4467	Involved in initiation control of chromosome replication
EVS87_019760	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EVS87_019765	COG2827	Endonuclease containing a URI domain
EVS87_019770	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EVS87_019775	COG2002	toxin-antitoxin pair type II binding
EVS87_019785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EVS87_019785	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EVS87_019790	COG0084	hydrolase, TatD family'
EVS87_019795	COG3584	3D domain protein
EVS87_019795	COG3583	domain protein
EVS87_019800	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EVS87_019805	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EVS87_019815	COG4466	Protein conserved in bacteria
EVS87_019825	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EVS87_019830	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EVS87_019835	COG0251	oxidation-reduction process
EVS87_019840	COG2088	sporulation resulting in formation of a cellular spore
EVS87_019850	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EVS87_019855	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EVS87_019860	COG0193	aminoacyl-tRNA hydrolase activity
EVS87_019870	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EVS87_019875	COG2002	toxin-antitoxin pair type II binding
EVS87_019880	COG2244	polysaccharide biosynthetic process
EVS87_019885	COG3956	TIGRFAM MazG family protein
EVS87_019890	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EVS87_019905	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EVS87_019910	COG1098	S1 RNA binding domain
EVS87_019925	COG2208	phosphoserine phosphatase activity
EVS87_019930	COG2304	oxidoreductase activity
EVS87_019935	COG0515	serine threonine protein kinase
EVS87_019940	COG0037	tRNA processing
EVS87_019950	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EVS87_019955	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EVS87_019960	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EVS87_019965	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EVS87_019970	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EVS87_019975	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EVS87_019980	COG0512	Glutamine amidotransferase of anthranilate synthase
EVS87_019985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EVS87_019990	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EVS87_019995	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EVS87_020000	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EVS87_020005	COG1396	sequence-specific DNA binding
EVS87_020010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EVS87_020015	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family