locus-tag	class	description
MMZ59_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MMZ59_00010	COG0592	DNA-directed DNA polymerase activity
MMZ59_00015	COG2501	S4 domain
MMZ59_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MMZ59_00030	COG0187	DNA topoisomerase II activity
MMZ59_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MMZ59_00070	COG0516	GMP reductase activity
MMZ59_00070	COG0517	IMP dehydrogenase activity
MMZ59_00075	COG1686	Belongs to the peptidase S11 family
MMZ59_00080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MMZ59_00085	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MMZ59_00090	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MMZ59_00095	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MMZ59_00110	COG1428	Deoxynucleoside kinase
MMZ59_00115	COG1428	Deoxynucleoside kinase
MMZ59_00120	COG1388	LysM domain
MMZ59_00120	COG3858	chitin binding
MMZ59_00125	COG1335	isochorismatase
MMZ59_00130	COG0590	tRNA wobble adenosine to inosine editing
MMZ59_00140	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MMZ59_00145	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MMZ59_00150	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MMZ59_00195	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
MMZ59_00200	COG3853	Toxic anion resistance protein (TelA)
MMZ59_00205	COG1982	Orn Lys Arg decarboxylase major
MMZ59_00210	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MMZ59_00215	COG3870	Protein conserved in bacteria
MMZ59_00220	COG1728	Protein conserved in bacteria
MMZ59_00225	COG0470	DNA polymerase III
MMZ59_00230	COG1774	PSP1 C-terminal conserved region
MMZ59_00235	COG4467	Involved in initiation control of chromosome replication
MMZ59_00240	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MMZ59_00245	COG2827	Endonuclease containing a URI domain
MMZ59_00250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MMZ59_00255	COG2002	toxin-antitoxin pair type II binding
MMZ59_00260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MMZ59_00260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MMZ59_00265	COG0084	hydrolase, TatD family'
MMZ59_00270	COG3583	domain protein
MMZ59_00270	COG3584	3D domain protein
MMZ59_00275	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MMZ59_00280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MMZ59_00290	COG4466	Protein conserved in bacteria
MMZ59_00300	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MMZ59_00305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MMZ59_00310	COG0251	oxidation-reduction process
MMZ59_00315	COG2088	sporulation resulting in formation of a cellular spore
MMZ59_00325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MMZ59_00330	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MMZ59_00335	COG0193	aminoacyl-tRNA hydrolase activity
MMZ59_00345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MMZ59_00350	COG2002	toxin-antitoxin pair type II binding
MMZ59_00355	COG2244	polysaccharide biosynthetic process
MMZ59_00360	COG3956	TIGRFAM MazG family protein
MMZ59_00365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MMZ59_00380	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MMZ59_00385	COG1098	S1 RNA binding domain
MMZ59_00400	COG2208	phosphoserine phosphatase activity
MMZ59_00405	COG2304	oxidoreductase activity
MMZ59_00410	COG0515	serine threonine protein kinase
MMZ59_00415	COG0037	tRNA processing
MMZ59_00420	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MMZ59_00425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MMZ59_00430	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MMZ59_00435	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MMZ59_00440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MMZ59_00445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MMZ59_00450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MMZ59_00455	COG0512	Glutamine amidotransferase of anthranilate synthase
MMZ59_00460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MMZ59_00465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MMZ59_00470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MMZ59_00475	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MMZ59_00480	COG1396	sequence-specific DNA binding
MMZ59_00485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MMZ59_00490	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MMZ59_00570	COG4463	regulation of RNA biosynthetic process
MMZ59_00575	COG3880	PFAM UvrB UvrC protein
MMZ59_00580	COG3869	Catalyzes the specific phosphorylation of arginine residues in
MMZ59_00585	COG0542	response to heat
MMZ59_00590	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MMZ59_00595	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MMZ59_00600	COG4956	integral membrane protein (PIN domain superfamily)
MMZ59_00605	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MMZ59_00610	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MMZ59_00615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MMZ59_00620	COG1045	serine acetyltransferase
MMZ59_00625	COG0215	cysteine-tRNA ligase activity
MMZ59_00630	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MMZ59_00635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MMZ59_00640	COG3688	RNA-binding protein containing a PIN domain
MMZ59_00645	COG1595	DNA-templated transcription, initiation
MMZ59_00650	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MMZ59_00655	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MMZ59_00660	COG0250	Participates in transcription elongation, termination and antitermination
MMZ59_00670	COG0081	regulation of translation
MMZ59_00675	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MMZ59_00680	COG0222	ribosome binding
MMZ59_00685	COG2813	Specifically methylates the guanine in position
MMZ59_00690	COG0085	RNA polymerase activity
MMZ59_00695	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MMZ59_00700	COG1358	cellular component organization or biogenesis
MMZ59_00705	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MMZ59_00710	COG0049	tRNA binding
MMZ59_00715	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MMZ59_00720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MMZ59_00725	COG0596	Alpha beta hydrolase
MMZ59_00735	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MMZ59_00740	COG0088	Forms part of the polypeptide exit tunnel
MMZ59_00745	COG0089	rRNA binding
MMZ59_00750	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MMZ59_00755	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MMZ59_00760	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MMZ59_00765	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MMZ59_00770	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MMZ59_00775	COG0255	Belongs to the universal ribosomal protein uL29 family
MMZ59_00780	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MMZ59_00785	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MMZ59_00790	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MMZ59_00795	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MMZ59_00800	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MMZ59_00805	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MMZ59_00810	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MMZ59_00815	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MMZ59_00820	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MMZ59_00825	COG1841	ribosomal large subunit assembly
MMZ59_00830	COG0200	Binds to the 23S rRNA
MMZ59_00835	COG0201	protein transport
MMZ59_00840	COG0563	adenylate kinase activity
MMZ59_00845	COG0024	Methionine aminopeptidase
MMZ59_00855	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MMZ59_00860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MMZ59_00865	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MMZ59_00870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MMZ59_00875	COG0202	RNA polymerase activity
MMZ59_00880	COG0203	ribosomal protein L17
MMZ59_00885	COG1122	ATPase activity
MMZ59_00890	COG1122	ATPase activity
MMZ59_00895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MMZ59_00900	COG0101	tRNA pseudouridine synthase activity
MMZ59_00905	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MMZ59_00910	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MMZ59_00935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MMZ59_00965	COG0860	N-Acetylmuramoyl-L-alanine amidase
MMZ59_00970	COG0489	protein tyrosine kinase activity
MMZ59_00980	COG2194	sulfuric ester hydrolase activity
MMZ59_00985	COG0726	polysaccharide deacetylase
MMZ59_01015	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MMZ59_01020	COG0659	secondary active sulfate transmembrane transporter activity
MMZ59_01025	COG0385	Bile acid
MMZ59_01030	COG3876	Protein conserved in bacteria
MMZ59_01035	COG1472	Belongs to the glycosyl hydrolase 3 family
MMZ59_01040	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MMZ59_01045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MMZ59_01045	COG1263	PTS System
MMZ59_01050	COG1737	Transcriptional regulator
MMZ59_01055	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MMZ59_01090	COG1595	DNA-templated transcription, initiation
MMZ59_01095	COG5662	AntiSigma factor
MMZ59_01100	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MMZ59_01105	COG4856	YbbR-like protein
MMZ59_01110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MMZ59_01115	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MMZ59_01130	COG1131	(ABC) transporter
MMZ59_01140	COG1136	(ABC) transporter
MMZ59_01150	COG1695	Transcriptional regulator
MMZ59_01160	COG1131	(ABC) transporter
MMZ59_01170	COG1413	lyase activity
MMZ59_01175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MMZ59_01190	COG2311	Membrane
MMZ59_01210	COG1476	TRANSCRIPTIONal
MMZ59_01220	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MMZ59_01225	COG2207	Transcriptional regulator
MMZ59_01240	COG1131	(ABC) transporter
MMZ59_01255	COG1113	amino acid transport
MMZ59_01260	COG0584	glycerophosphoryl diester phosphodiesterase
MMZ59_01265	COG2271	Major facilitator Superfamily
MMZ59_01275	COG1331	Highly conserved protein containing a thioredoxin domain
MMZ59_01285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MMZ59_01300	COG0640	Transcriptional regulator
MMZ59_01315	COG1937	Protein conserved in bacteria
MMZ59_01320	COG2210	Belongs to the sulfur carrier protein TusA family
MMZ59_01330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MMZ59_01330	COG0425	Belongs to the sulfur carrier protein TusA family
MMZ59_01335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MMZ59_01335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MMZ59_01340	COG0425	Belongs to the sulfur carrier protein TusA family
MMZ59_01345	COG0730	response to heat
MMZ59_01355	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MMZ59_01360	COG2814	Major facilitator Superfamily
MMZ59_01375	COG1846	Transcriptional regulator
MMZ59_01380	COG1683	Conserved Protein
MMZ59_01390	COG0656	L-ascorbic acid biosynthetic process
MMZ59_01395	COG0371	Dehydrogenase
MMZ59_01400	COG1054	Belongs to the UPF0176 family
MMZ59_01405	COG0531	amino acid
MMZ59_01415	COG3711	transcriptional antiterminator
MMZ59_01420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MMZ59_01420	COG2190	(PTS) system
MMZ59_01420	COG1263	PTS System
MMZ59_01425	COG2723	6-phospho-beta-galactosidase activity
MMZ59_01440	COG3711	transcriptional antiterminator
MMZ59_01440	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MMZ59_01445	COG1940	carbohydrate kinase activity
MMZ59_01450	COG0383	alpha-mannosidase activity
MMZ59_01455	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MMZ59_01460	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MMZ59_01465	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MMZ59_01465	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MMZ59_01470	COG1404	Belongs to the peptidase S8 family
MMZ59_01480	COG0833	amino acid
MMZ59_01485	COG2040	homocysteine
MMZ59_01490	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MMZ59_01495	COG1695	Transcriptional regulator
MMZ59_01510	COG2814	Major facilitator Superfamily
MMZ59_01515	COG0456	acetyltransferase
MMZ59_01530	COG1404	Belongs to the peptidase S8 family
MMZ59_01540	COG1309	transcriptional regulator
MMZ59_01545	COG1917	Cupin 2, conserved barrel domain protein
MMZ59_01550	COG1063	alcohol dehydrogenase
MMZ59_01555	COG1846	Transcriptional regulator
MMZ59_01560	COG0318	PFAM AMP-dependent synthetase and ligase
MMZ59_01565	COG0531	amino acid
MMZ59_01575	COG0596	Alpha beta hydrolase
MMZ59_01580	COG1115	amino acid carrier protein
MMZ59_01585	COG2066	Belongs to the glutaminase family
MMZ59_01590	COG4191	Histidine kinase
MMZ59_01595	COG0784	Response regulator, receiver
MMZ59_01600	COG3012	SEC-C Motif Domain Protein
MMZ59_01600	COG1405	negative regulation of cell septum assembly
MMZ59_01610	COG2197	response regulator
MMZ59_01615	COG4585	Histidine kinase
MMZ59_01625	COG0667	Aldo Keto reductase
MMZ59_01630	COG3290	protein histidine kinase activity
MMZ59_01635	COG3279	Response regulator of the LytR AlgR family
MMZ59_01640	COG4555	ABC transporter
MMZ59_01645	COG1668	transmembrane transport
MMZ59_01665	COG3773	Cell wall hydrolase
MMZ59_01670	COG1028	Short-chain dehydrogenase reductase Sdr
MMZ59_01680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MMZ59_01685	COG2310	stress, protein
MMZ59_01690	COG2310	stress, protein
MMZ59_01695	COG2310	stress, protein
MMZ59_01700	COG0861	Integral membrane protein TerC family
MMZ59_01730	COG3853	Toxic anion resistance protein (TelA)
MMZ59_01735	COG0517	IMP dehydrogenase activity
MMZ59_01735	COG4175	Glycine betaine
MMZ59_01740	COG4176	ABC-type proline glycine betaine transport system permease component
MMZ59_01745	COG2113	Glycine betaine
MMZ59_01760	COG1473	amidohydrolase
MMZ59_01765	COG1288	antiporter activity
MMZ59_01770	COG0039	L-malate dehydrogenase activity
MMZ59_01775	COG1620	l-lactate permease
MMZ59_01780	COG1609	Transcriptional regulator
MMZ59_01785	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MMZ59_01790	COG0561	phosphatase activity
MMZ59_01795	COG0673	inositol 2-dehydrogenase activity
MMZ59_01800	COG0738	Major facilitator superfamily
MMZ59_01805	COG1280	lysine exporter protein (LysE YggA)
MMZ59_01820	COG3403	YqcI/YcgG family
MMZ59_01825	COG1113	amino acid transport
MMZ59_01830	COG3665	Urea carboxylase-associated protein
MMZ59_01835	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MMZ59_01845	COG1012	belongs to the aldehyde dehydrogenase family
MMZ59_01850	COG0710	3-dehydroquinate dehydratase activity
MMZ59_01855	COG0028	Belongs to the TPP enzyme family
MMZ59_01865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MMZ59_01870	COG2271	Major facilitator Superfamily
MMZ59_01885	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MMZ59_01890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MMZ59_01900	COG0477	Major facilitator Superfamily
MMZ59_01905	COG2226	methyltransferase
MMZ59_01910	COG0583	DNA-binding transcription factor activity
MMZ59_01915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MMZ59_01920	COG3458	cephalosporin-C deacetylase activity
MMZ59_01930	COG3541	Predicted nucleotidyltransferase
MMZ59_01935	COG0506	proline dehydrogenase activity
MMZ59_01940	COG1012	belongs to the aldehyde dehydrogenase family
MMZ59_01945	COG2508	Transcriptional regulator
MMZ59_01950	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MMZ59_01955	COG0765	amino acid transport
MMZ59_01960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MMZ59_01970	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MMZ59_01975	COG1522	sequence-specific DNA binding
MMZ59_01980	COG2746	aminoglycoside 3-N-acetyltransferase activity
MMZ59_01990	COG3290	protein histidine kinase activity
MMZ59_01990	COG0840	transmembrane signaling receptor activity
MMZ59_01995	COG3209	COG3209 Rhs family protein
MMZ59_02015	COG3842	ATPase activity
MMZ59_02020	COG1176	ABC-type spermidine putrescine transport system, permease component I
MMZ59_02030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MMZ59_02035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MMZ59_02040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MMZ59_02055	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
MMZ59_02060	COG0697	spore germination
MMZ59_02065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MMZ59_02075	COG2207	Transcriptional regulator
MMZ59_02075	COG3708	Transcriptional regulator
MMZ59_02085	COG2364	Membrane
MMZ59_02090	COG1126	abc transporter atp-binding protein
MMZ59_02095	COG0765	amino acid transport
MMZ59_02100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MMZ59_02105	COG0412	Dienelactone hydrolase
MMZ59_02110	COG0833	amino acid
MMZ59_02115	COG3104	oligopeptide transport
MMZ59_02120	COG5434	Belongs to the glycosyl hydrolase 28 family
MMZ59_02125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MMZ59_02130	COG0456	acetyltransferase
MMZ59_02135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MMZ59_02140	COG0765	amino acid transport
MMZ59_02145	COG1126	abc transporter atp-binding protein
MMZ59_02150	COG1473	amidohydrolase
MMZ59_02155	COG2079	MmgE PrpD family protein
MMZ59_02160	COG0745	RESPONSE REGULATOR receiver
MMZ59_02165	COG3850	Histidine kinase
MMZ59_02165	COG5002	protein histidine kinase activity
MMZ59_02170	COG1366	Belongs to the anti-sigma-factor antagonist family
MMZ59_02175	COG0527	aspartate kinase activity
MMZ59_02180	COG2814	Major facilitator Superfamily
MMZ59_02185	COG1309	transcriptional regulator
MMZ59_02195	COG0640	Transcriptional regulator
MMZ59_02205	COG0583	DNA-binding transcription factor activity
MMZ59_02210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MMZ59_02215	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MMZ59_02220	COG0531	amino acid
MMZ59_02225	COG1012	belongs to the aldehyde dehydrogenase family
MMZ59_02230	COG2249	NAD(P)H dehydrogenase (quinone) activity
MMZ59_02235	COG4549	nuclear export factor GLE1
MMZ59_02240	COG2372	response to copper ion
MMZ59_02240	COG1276	copper resistance
MMZ59_02245	COG2213	PTS system mannitol-specific
MMZ59_02250	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MMZ59_02255	COG0246	Mannitol dehydrogenase
MMZ59_02260	COG0840	transmembrane signaling receptor activity
MMZ59_02295	COG0346	lactoylglutathione lyase activity
MMZ59_02305	COG0561	phosphatase activity
MMZ59_02310	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MMZ59_02315	COG1914	H( )-stimulated, divalent metal cation uptake system
MMZ59_02320	COG4336	lyase activity
MMZ59_02325	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MMZ59_02330	COG1984	allophanate hydrolase subunit 2
MMZ59_02335	COG1414	Transcriptional regulator
MMZ59_02340	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MMZ59_02345	COG2755	lipolytic protein G-D-S-L family
MMZ59_02355	COG3711	transcriptional antiterminator
MMZ59_02360	COG2226	methyltransferase
MMZ59_02365	COG1028	Short-chain dehydrogenase reductase Sdr
MMZ59_02370	COG3871	stress protein (general stress protein 26)
MMZ59_02390	COG2814	Major facilitator Superfamily
MMZ59_02395	COG1802	Transcriptional regulator
MMZ59_02400	COG1917	Cupin 2, conserved barrel domain protein
MMZ59_02400	COG2207	Transcriptional regulator
MMZ59_02405	COG0697	spore germination
MMZ59_02410	COG0473	3-isopropylmalate dehydrogenase activity
MMZ59_02415	COG0551	DNA topoisomerase type I activity
MMZ59_02415	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MMZ59_02420	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MMZ59_02425	COG3706	GGDEF domain
MMZ59_02430	COG5298	Protein conserved in bacteria
MMZ59_02435	COG1215	transferase activity, transferring glycosyl groups
MMZ59_02445	COG0531	amino acid
MMZ59_02450	COG0028	Belongs to the TPP enzyme family
MMZ59_02455	COG5444	nuclease activity
MMZ59_02475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MMZ59_02480	COG1914	H( )-stimulated, divalent metal cation uptake system
MMZ59_02485	COG2261	transglycosylase associated protein
MMZ59_02490	COG2217	Heavy metal translocating P-type atpase
MMZ59_02495	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MMZ59_02500	COG3290	protein histidine kinase activity
MMZ59_02505	COG4565	transcriptional regulatory protein
MMZ59_02510	COG1301	dicarboxylic acid transport
MMZ59_02515	COG0628	permease
MMZ59_02520	COG1301	dicarboxylic acid transport
MMZ59_02525	COG1131	(ABC) transporter
MMZ59_02530	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MMZ59_02545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MMZ59_02550	COG1181	Belongs to the D-alanine--D-alanine ligase family
MMZ59_02555	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MMZ59_02570	COG0513	Belongs to the DEAD box helicase family
MMZ59_02575	COG3402	PFAM membrane-flanked domain
MMZ59_02580	COG3428	Bacterial PH domain
MMZ59_02585	COG0705	Rhomboid family
MMZ59_02590	COG0736	holo-[acyl-carrier-protein] synthase activity
MMZ59_02595	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MMZ59_02600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MMZ59_02605	COG0864	Transcriptional regulator
MMZ59_02610	COG2337	Toxic component of a toxin-antitoxin (TA) module
MMZ59_02615	COG1366	Belongs to the anti-sigma-factor antagonist family
MMZ59_02620	COG1366	Belongs to the anti-sigma-factor antagonist family
MMZ59_02625	COG2172	sigma factor antagonist activity
MMZ59_02630	COG2208	phosphoserine phosphatase activity
MMZ59_02635	COG1366	Belongs to the anti-sigma-factor antagonist family
MMZ59_02640	COG2172	sigma factor antagonist activity
MMZ59_02645	COG1191	sigma factor activity
MMZ59_02650	COG2208	phosphoserine phosphatase activity
MMZ59_02655	COG2183	response to ionizing radiation
MMZ59_02665	COG3091	SprT-like family
MMZ59_02670	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MMZ59_02675	COG0022	dehydrogenase e1 component
MMZ59_02680	COG0508	dehydrogenase complex catalyzes the overall conversion of
MMZ59_02685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MMZ59_02690	COG3284	Transcriptional regulator
MMZ59_02735	COG1278	Cold shock
MMZ59_02740	COG1263	PTS System
MMZ59_02740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MMZ59_02740	COG2190	(PTS) system
MMZ59_02745	COG3394	polysaccharide catabolic process
MMZ59_02750	COG3711	transcriptional antiterminator
MMZ59_02755	COG1064	alcohol dehydrogenase
MMZ59_02760	COG0789	Transcriptional regulator
MMZ59_02780	COG0477	Major facilitator Superfamily
MMZ59_02785	COG0657	acetylesterase activity
MMZ59_02795	COG4221	oxidoreductase activity
MMZ59_02805	COG0252	asparaginase activity
MMZ59_02810	COG2267	carboxylic ester hydrolase activity
MMZ59_02830	COG2814	Major facilitator Superfamily
MMZ59_02875	COG1309	transcriptional regulator
MMZ59_02880	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MMZ59_02885	COG1846	Transcriptional regulator
MMZ59_02890	COG0778	Nitroreductase
MMZ59_02905	COG1396	sequence-specific DNA binding
MMZ59_02925	COG4122	O-methyltransferase activity
MMZ59_02935	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MMZ59_02940	COG0697	spore germination
MMZ59_02950	COG1301	dicarboxylic acid transport
MMZ59_02990	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MMZ59_02995	COG0802	atpase or kinase
MMZ59_03000	COG1214	PFAM Peptidase M22, glycoprotease
MMZ59_03005	COG0456	acetyltransferase
MMZ59_03010	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MMZ59_03015	COG0488	(ABC) transporter
MMZ59_03020	COG0315	cyclic pyranopterin monophosphate synthase activity
MMZ59_03025	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MMZ59_03030	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MMZ59_03035	COG0805	protein transport
MMZ59_03050	COG1266	CAAX protease self-immunity
MMZ59_03055	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MMZ59_03060	COG0459	protein refolding
MMZ59_03105	COG2808	Putative FMN-binding domain
MMZ59_03135	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MMZ59_03140	COG0823	Involved in the tonB-independent uptake of proteins
MMZ59_03150	COG2132	Multicopper oxidase
MMZ59_03155	COG1113	amino acid transport
MMZ59_03160	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MMZ59_03165	COG0714	Associated with various cellular activities
MMZ59_03170	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
MMZ59_03175	COG1305	Transglutaminase-like
MMZ59_03180	COG0519	Catalyzes the synthesis of GMP from XMP
MMZ59_03180	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MMZ59_03205	COG1595	DNA-templated transcription, initiation
MMZ59_03215	COG2814	Major facilitator Superfamily
MMZ59_03220	COG0583	DNA-binding transcription factor activity
MMZ59_03245	COG2252	PERMEase
MMZ59_03255	COG5583	Uncharacterized small protein (DUF2292)
MMZ59_03260	COG3064	Membrane
MMZ59_03265	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
MMZ59_03275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MMZ59_03280	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MMZ59_03285	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MMZ59_03290	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MMZ59_03295	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MMZ59_03300	COG0047	phosphoribosylformylglycinamidine synthase activity
MMZ59_03305	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MMZ59_03310	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MMZ59_03315	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MMZ59_03320	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MMZ59_03325	COG0138	bifunctional purine biosynthesis protein purh
MMZ59_03330	COG0151	Belongs to the GarS family
MMZ59_03345	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MMZ59_03350	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MMZ59_03355	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MMZ59_03360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MMZ59_03370	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MMZ59_03375	COG4496	protein, YerC YecD
MMZ59_03385	COG0069	glutamate synthase activity
MMZ59_03400	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MMZ59_03405	COG0210	DNA helicase
MMZ59_03410	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MMZ59_03415	COG4851	CamS sex pheromone cAM373 precursor
MMZ59_03420	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MMZ59_03425	COG1285	pathogenesis
MMZ59_03430	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MMZ59_03435	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MMZ59_03440	COG0154	amidase activity
MMZ59_03445	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MMZ59_03450	COG1309	transcriptional regulator
MMZ59_03455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MMZ59_03460	COG1957	nucleoside hydrolase
MMZ59_03465	COG1597	lipid kinase activity
MMZ59_03470	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MMZ59_03480	COG5444	nuclease activity
MMZ59_03485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MMZ59_03500	COG1959	2 iron, 2 sulfur cluster binding
MMZ59_03505	COG0492	ferredoxin-NADP+ reductase activity
MMZ59_03520	COG1486	melibiose metabolic process
MMZ59_03530	COG2211	Major facilitator Superfamily
MMZ59_03560	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MMZ59_03565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MMZ59_03570	COG1442	glycosyl transferase family 8
MMZ59_03575	COG1216	Glycosyl transferase, family 2
MMZ59_03580	COG1442	glycosyl transferase family 8
MMZ59_03585	COG2223	nitrite transmembrane transporter activity
MMZ59_03595	COG0471	metal ion transport
MMZ59_03610	COG0071	Belongs to the small heat shock protein (HSP20) family
MMZ59_03625	COG0531	amino acid
MMZ59_03630	COG0457	Tetratricopeptide repeat
MMZ59_03630	COG0463	Glycosyl transferase, family 2
MMZ59_03635	COG0488	(ABC) transporter
MMZ59_03640	COG1469	GTP cyclohydrolase I activity
MMZ59_03645	COG0789	Transcriptional regulator
MMZ59_03650	COG2814	Major facilitator Superfamily
MMZ59_03655	COG0488	(ABC) transporter
MMZ59_03660	COG0513	Belongs to the DEAD box helicase family
MMZ59_03665	COG2130	NADP-dependent
MMZ59_03685	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MMZ59_03685	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MMZ59_03690	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MMZ59_03700	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MMZ59_03700	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MMZ59_03710	COG3290	protein histidine kinase activity
MMZ59_03715	COG4565	transcriptional regulatory protein
MMZ59_03720	COG3181	Tripartite tricarboxylate transporter family receptor
MMZ59_03725	COG2851	Citrate transporter
MMZ59_03735	COG3479	Phenolic acid decarboxylase
MMZ59_03740	COG1695	Transcriptional regulator
MMZ59_03745	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MMZ59_03755	COG1254	Belongs to the acylphosphatase family
MMZ59_03760	COG2258	MOSC domain
MMZ59_03775	COG0024	Methionine aminopeptidase
MMZ59_03780	COG1263	PTS System
MMZ59_03780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MMZ59_03785	COG3739	integral membrane protein
MMZ59_03800	COG1368	sulfuric ester hydrolase activity
MMZ59_03805	COG0076	glutamate decarboxylase activity
MMZ59_03820	COG1263	PTS System
MMZ59_03820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MMZ59_03825	COG0366	Alpha amylase catalytic
MMZ59_03830	COG2188	Transcriptional regulator
MMZ59_03840	COG0737	Belongs to the 5'-nucleotidase family
MMZ59_03845	COG0693	protein deglycase activity
MMZ59_03850	COG4840	Belongs to the UPF0435 family
MMZ59_03855	COG1115	amino acid carrier protein
MMZ59_03860	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MMZ59_03865	COG4980	gas vesicle protein
MMZ59_03870	COG1295	ribonuclease BN
MMZ59_03875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MMZ59_03880	COG0477	Major facilitator Superfamily
MMZ59_03890	COG0387	Pfam Sodium calcium exchanger
MMZ59_03900	COG0217	transcriptional regulatory protein
MMZ59_03910	COG0668	transmembrane transport
MMZ59_03915	COG0535	radical SAM domain protein
MMZ59_03925	COG0726	polysaccharide deacetylase
MMZ59_03935	COG0598	Magnesium transport protein CorA
MMZ59_03945	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MMZ59_03950	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MMZ59_03965	COG0583	DNA-binding transcription factor activity
MMZ59_03970	COG1942	4-Oxalocrotonate Tautomerase
MMZ59_03975	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MMZ59_03980	COG0789	Transcriptional regulator
MMZ59_03985	COG2814	Major facilitator Superfamily
MMZ59_04035	COG2076	Multidrug Resistance protein
MMZ59_04040	COG2076	Multidrug Resistance protein
MMZ59_04045	COG1309	transcriptional regulator
MMZ59_04055	COG4637	Psort location Cytoplasmic, score
MMZ59_04060	COG2755	lipolytic protein G-D-S-L family
MMZ59_04065	COG0492	ferredoxin-NADP+ reductase activity
MMZ59_04070	COG2169	Transcriptional regulator
MMZ59_04075	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MMZ59_04080	COG1132	(ABC) transporter
MMZ59_04085	COG1742	UPF0060 membrane protein
MMZ59_04090	COG1595	DNA-templated transcription, initiation
MMZ59_04110	COG2318	DinB family
MMZ59_04120	COG1846	Transcriptional regulator
MMZ59_04125	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MMZ59_04125	COG0392	lysyltransferase activity
MMZ59_04145	COG0778	Nitroreductase
MMZ59_04160	COG1090	epimerase
MMZ59_04165	COG2137	regulation of response to DNA damage stimulus
MMZ59_04190	COG0463	Glycosyl transferase, family 2
MMZ59_04195	COG4485	Bacterial membrane protein, YfhO
MMZ59_04200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MMZ59_04215	COG2140	Oxalate decarboxylase
MMZ59_04225	COG1191	sigma factor activity
MMZ59_04235	COG1988	membrane-bound metal-dependent
MMZ59_04240	COG1194	a g-specific adenine glycosylase
MMZ59_04250	COG1028	Short-chain dehydrogenase reductase Sdr
MMZ59_04265	COG3557	Belongs to the UPF0374 family
MMZ59_04270	COG1132	(ABC) transporter
MMZ59_04275	COG0444	Belongs to the ABC transporter superfamily
MMZ59_04280	COG4608	Belongs to the ABC transporter superfamily
MMZ59_04285	COG0747	negative chemotaxis
MMZ59_04290	COG0601	transmembrane transport
MMZ59_04295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MMZ59_04305	COG4129	membrane
MMZ59_04310	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MMZ59_04315	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MMZ59_04320	COG0735	belongs to the Fur family
MMZ59_04470	COG1368	sulfuric ester hydrolase activity
MMZ59_04475	COG0681	Belongs to the peptidase S26 family
MMZ59_04480	COG2873	o-acetylhomoserine
MMZ59_04490	COG1116	anion transmembrane transporter activity
MMZ59_04495	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MMZ59_04500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MMZ59_04515	COG1131	(ABC) transporter
MMZ59_04545	COG3382	B3 4 domain protein
MMZ59_04550	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MMZ59_04560	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MMZ59_04565	COG2766	serine protein kinase
MMZ59_04570	COG2718	Belongs to the UPF0229 family
MMZ59_04575	COG1566	PFAM secretion protein HlyD family protein
MMZ59_04580	COG2814	Major facilitator Superfamily
MMZ59_04585	COG0655	NAD(P)H dehydrogenase (quinone) activity
MMZ59_04595	COG1278	Cold shock
MMZ59_04600	COG3706	GGDEF domain
MMZ59_04625	COG5577	PFAM Coat F domain
MMZ59_04630	COG5002	protein histidine kinase activity
MMZ59_04635	COG4085	toxin activity
MMZ59_04635	COG1525	nuclease
MMZ59_04635	COG0737	Belongs to the 5'-nucleotidase family
MMZ59_04640	COG3764	Sortase (surface protein transpeptidase)
MMZ59_04645	COG0564	pseudouridine synthase activity
MMZ59_04655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MMZ59_04660	COG3153	acetyltransferase
MMZ59_04660	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MMZ59_04680	COG3835	regulator
MMZ59_04685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MMZ59_04690	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MMZ59_04695	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MMZ59_04700	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MMZ59_04705	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MMZ59_04710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MMZ59_04715	COG2203	Gaf domain
MMZ59_04715	COG4585	Histidine kinase
MMZ59_04720	COG2197	response regulator
MMZ59_04735	COG0753	catalase activity
MMZ59_04740	COG1959	2 iron, 2 sulfur cluster binding
MMZ59_04745	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MMZ59_04745	COG1017	nitric oxide dioxygenase activity
MMZ59_04750	COG2719	SpoVR family
MMZ59_04755	COG1785	Belongs to the alkaline phosphatase family
MMZ59_04760	COG1388	LysM domain
MMZ59_04760	COG0791	NLP P60 protein
MMZ59_04765	COG0531	amino acid
MMZ59_04780	COG1595	DNA-templated transcription, initiation
MMZ59_04785	COG0204	Acyl-transferase
MMZ59_04790	COG1253	flavin adenine dinucleotide binding
MMZ59_04795	COG0789	Transcriptional regulator
MMZ59_04800	COG1253	flavin adenine dinucleotide binding
MMZ59_04815	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MMZ59_04820	COG0584	glycerophosphoryl diester phosphodiesterase
MMZ59_04830	COG0668	transmembrane transport
MMZ59_04835	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MMZ59_04840	COG0726	polysaccharide deacetylase
MMZ59_04845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MMZ59_04850	COG0589	response to stress
MMZ59_04855	COG1132	(ABC) transporter
MMZ59_04860	COG1132	(ABC) transporter
MMZ59_04865	COG0702	epimerase
MMZ59_04875	COG3842	ATPase activity
MMZ59_04880	COG2508	Transcriptional regulator
MMZ59_04890	COG0189	ligase activity
MMZ59_04895	COG0189	ligase activity
MMZ59_04900	COG4399	Belongs to the UPF0754 family
MMZ59_04905	COG3679	Belongs to the UPF0342 family
MMZ59_04910	COG0561	phosphatase activity
MMZ59_04915	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MMZ59_04925	COG0475	glutathione-regulated potassium exporter activity
MMZ59_04930	COG0490	domain, Protein
MMZ59_04940	COG1024	Enoyl-CoA hydratase
MMZ59_04950	COG0420	3'-5' exonuclease activity
MMZ59_04955	COG4717	serine-type aminopeptidase activity
MMZ59_04960	COG3481	metal-dependent phosphohydrolase, HD sub domain
MMZ59_04970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MMZ59_05000	COG1846	Transcriptional regulator
MMZ59_05005	COG4980	gas vesicle protein
MMZ59_05020	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MMZ59_05025	COG0537	adenosine 5'-monophosphoramidase activity
MMZ59_05030	COG1131	(ABC) transporter
MMZ59_05035	COG4473	ABC transporter
MMZ59_05045	COG1473	amidohydrolase
MMZ59_05055	COG2329	Antibiotic biosynthesis monooxygenase
MMZ59_05060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MMZ59_05065	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MMZ59_05070	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MMZ59_05075	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MMZ59_05080	COG1309	transcriptional regulator
MMZ59_05085	COG1511	domain protein
MMZ59_05090	COG1363	Peptidase, m42
MMZ59_05095	COG1301	dicarboxylic acid transport
MMZ59_05105	COG1234	tRNA 3'-trailer cleavage
MMZ59_05110	COG0095	Lipoate-protein ligase
MMZ59_05115	COG0318	PFAM AMP-dependent synthetase and ligase
MMZ59_05125	COG0501	Belongs to the peptidase M48B family
MMZ59_05130	COG1404	Belongs to the peptidase S8 family
MMZ59_05135	COG0406	alpha-ribazole phosphatase activity
MMZ59_05140	COG0840	transmembrane signaling receptor activity
MMZ59_05145	COG0723	plastoquinol--plastocyanin reductase activity
MMZ59_05145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MMZ59_05150	COG1028	Short-chain dehydrogenase reductase Sdr
MMZ59_05160	COG4903	ComK protein
MMZ59_05175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MMZ59_05180	COG2814	Major facilitator Superfamily
MMZ59_05185	COG2732	(Barnase) inhibitor
MMZ59_05190	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MMZ59_05195	COG4605	iron ion homeostasis
MMZ59_05200	COG4604	ABC transporter, ATP-binding protein
MMZ59_05205	COG4607	ABC-type enterochelin transport system periplasmic component
MMZ59_05210	COG1316	TRANSCRIPTIONal
MMZ59_05225	COG0398	Pfam SNARE associated Golgi protein
MMZ59_05230	COG0681	Belongs to the peptidase S26 family
MMZ59_05235	COG3180	Ammonia monooxygenase
MMZ59_05250	COG2259	Doxx family
MMZ59_05255	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
MMZ59_05260	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
MMZ59_05265	COG1074	ATP-dependent DNA helicase activity
MMZ59_05270	COG0420	3'-5' exonuclease activity
MMZ59_05275	COG0419	ATPase involved in DNA repair
MMZ59_05280	COG1403	HNH endonuclease
MMZ59_05320	COG5337	Spore coat protein CotH
MMZ59_05330	COG0179	Fumarylacetoacetate (FAA) hydrolase
MMZ59_05345	COG0367	asparagine synthase
MMZ59_05360	COG1562	ergosterol biosynthetic process
MMZ59_05365	COG0534	Mate efflux family protein
MMZ59_05370	COG1917	Cupin 2, conserved barrel domain protein
MMZ59_05370	COG2207	Transcriptional regulator
MMZ59_05395	COG0076	glutamate decarboxylase activity
MMZ59_05430	COG0646	methionine synthase
MMZ59_05430	COG1410	methionine synthase
MMZ59_05435	COG0646	methionine synthase
MMZ59_05435	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MMZ59_05440	COG1666	GTP binding
MMZ59_05445	COG2996	Protein conserved in bacteria
MMZ59_05450	COG1744	ABC transporter substrate-binding protein PnrA-like
MMZ59_05455	COG0840	transmembrane signaling receptor activity
MMZ59_05460	COG1307	EDD domain protein, DegV family
MMZ59_05465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MMZ59_05485	COG0561	phosphatase activity
MMZ59_05490	COG1073	alpha beta
MMZ59_05495	COG2151	metal-sulfur cluster biosynthetic enzyme
MMZ59_05500	COG0277	FAD linked oxidase domain protein
MMZ59_05505	COG2271	Major facilitator Superfamily
MMZ59_05510	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MMZ59_05515	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MMZ59_05520	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MMZ59_05525	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MMZ59_05530	COG0505	Belongs to the CarA family
MMZ59_05535	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MMZ59_05540	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MMZ59_05550	COG2814	Major facilitator Superfamily
MMZ59_05560	COG2267	carboxylic ester hydrolase activity
MMZ59_05570	COG1744	ABC transporter substrate-binding protein PnrA-like
MMZ59_05585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MMZ59_05590	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MMZ59_05595	COG5504	Zn-dependent protease
MMZ59_05600	COG0444	Belongs to the ABC transporter superfamily
MMZ59_05605	COG4608	Belongs to the ABC transporter superfamily
MMZ59_05615	COG0601	transmembrane transport
MMZ59_05620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MMZ59_05630	COG0180	Tryptophanyl-tRNA synthetase
MMZ59_05635	COG4166	transmembrane transport
MMZ59_05640	COG0601	transmembrane transport
MMZ59_05645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MMZ59_05650	COG0444	Belongs to the ABC transporter superfamily
MMZ59_05655	COG4608	Belongs to the ABC transporter superfamily
MMZ59_05665	COG0456	acetyltransferase
MMZ59_05670	COG1393	Belongs to the ArsC family
MMZ59_05675	COG0861	Integral membrane protein TerC family
MMZ59_05680	COG4862	establishment of competence for transformation
MMZ59_05685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MMZ59_05695	COG1164	Oligoendopeptidase f
MMZ59_05705	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MMZ59_05710	COG2346	COG2346, Truncated hemoglobins
MMZ59_05715	COG0741	lytic transglycosylase activity
MMZ59_05720	COG4116	CYTH
MMZ59_05730	COG2357	RelA SpoT domain protein
MMZ59_05735	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MMZ59_05740	COG0564	pseudouridine synthase activity
MMZ59_05745	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MMZ59_05750	COG0569	domain protein
MMZ59_05750	COG0475	glutathione-regulated potassium exporter activity
MMZ59_05755	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MMZ59_05760	COG0352	thiamine-phosphate diphosphorylase activity
MMZ59_05770	COG2104	thiamine diphosphate biosynthetic process
MMZ59_05775	COG2022	thiamine diphosphate biosynthetic process
MMZ59_05780	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MMZ59_05785	COG0351	phosphomethylpyrimidine kinase
MMZ59_05790	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MMZ59_05845	COG0210	DNA helicase
MMZ59_05855	COG2153	protein acetylation
MMZ59_05860	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MMZ59_05865	COG2382	esterase
MMZ59_05870	COG0626	cystathionine gamma-synthase activity
MMZ59_05875	COG0626	cystathionine gamma-synthase activity
MMZ59_05905	COG0825	malonyl-CoA metabolic process
MMZ59_05925	COG0457	Tetratricopeptide repeat
MMZ59_05940	COG0583	DNA-binding transcription factor activity
MMZ59_05960	COG0583	DNA-binding transcription factor activity
MMZ59_05965	COG2807	transmembrane transport
MMZ59_06000	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MMZ59_06010	COG1309	transcriptional regulator
MMZ59_06020	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MMZ59_06025	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MMZ59_06030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MMZ59_06035	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MMZ59_06055	COG4195	phage-related replication protein
MMZ59_06060	COG2856	Zn peptidase
MMZ59_06065	COG5632	N-Acetylmuramoyl-L-alanine amidase
MMZ59_06065	COG3409	Peptidoglycan-binding domain 1 protein
MMZ59_06080	COG0306	phosphate transporter
MMZ59_06085	COG1392	Phosphate transport regulator
MMZ59_06095	COG0405	Gamma-glutamyltransferase
MMZ59_06100	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MMZ59_06110	COG4208	sulfate ABC transporter
MMZ59_06115	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MMZ59_06125	COG3775	system Galactitol-specific IIC component
MMZ59_06140	COG1063	alcohol dehydrogenase
MMZ59_06145	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MMZ59_06150	COG0022	dehydrogenase e1 component
MMZ59_06150	COG0508	dehydrogenase complex catalyzes the overall conversion of
MMZ59_06155	COG0508	dehydrogenase complex catalyzes the overall conversion of
MMZ59_06160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MMZ59_06165	COG1028	Short-chain dehydrogenase reductase Sdr
MMZ59_06170	COG1028	Short-chain dehydrogenase reductase Sdr
MMZ59_06175	COG2390	Transcriptional regulator
MMZ59_06185	COG0531	amino acid
MMZ59_06190	COG0346	lactoylglutathione lyase activity
MMZ59_06195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MMZ59_06200	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MMZ59_06205	COG2362	D-Aminopeptidase
MMZ59_06210	COG0601	transmembrane transport
MMZ59_06215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MMZ59_06220	COG0444	Belongs to the ABC transporter superfamily
MMZ59_06225	COG4166	transmembrane transport
MMZ59_06230	COG1619	proteins homologs of microcin C7 resistance protein MccF
MMZ59_06235	COG4948	Mandelate Racemase Muconate Lactonizing
MMZ59_06240	COG0791	NLP P60 protein
MMZ59_06245	COG4608	Belongs to the ABC transporter superfamily
MMZ59_06250	COG1834	amidinotransferase
MMZ59_06255	COG1607	acyl-coa hydrolase
MMZ59_06260	COG1695	Transcriptional regulator
MMZ59_06275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MMZ59_06285	COG2076	Multidrug Resistance protein
MMZ59_06290	COG2076	Multidrug Resistance protein
MMZ59_06300	COG0788	formyltetrahydrofolate deformylase activity
MMZ59_06305	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MMZ59_06310	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MMZ59_06315	COG0457	Tetratricopeptide repeat
MMZ59_06325	COG1764	response to oxidative stress
MMZ59_06330	COG1846	Transcriptional regulator
MMZ59_06335	COG1764	response to oxidative stress
MMZ59_06340	COG0590	tRNA wobble adenosine to inosine editing
MMZ59_06345	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MMZ59_06350	COG1404	Belongs to the peptidase S8 family
MMZ59_06365	COG0745	RESPONSE REGULATOR receiver
MMZ59_06370	COG3850	Histidine kinase
MMZ59_06370	COG5002	protein histidine kinase activity
MMZ59_06375	COG3212	peptidase
MMZ59_06380	COG3212	peptidase
MMZ59_06390	COG2239	Acts as a magnesium transporter
MMZ59_06400	COG0583	DNA-binding transcription factor activity
MMZ59_06410	COG0789	Transcriptional regulator
MMZ59_06425	COG1846	Transcriptional regulator
MMZ59_06430	COG3300	MHYT domain
MMZ59_06430	COG5001	Diguanylate cyclase
MMZ59_06435	COG0586	Pfam SNARE associated Golgi protein
MMZ59_06440	COG0861	Integral membrane protein TerC family
MMZ59_06445	COG1191	sigma factor activity
MMZ59_06465	COG0501	Belongs to the peptidase M48B family
MMZ59_06470	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MMZ59_06475	COG2323	membrane
MMZ59_06490	COG3594	Acyltransferase
MMZ59_06495	COG5002	protein histidine kinase activity
MMZ59_06500	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MMZ59_06505	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MMZ59_06510	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MMZ59_06515	COG0436	Aminotransferase
MMZ59_06520	COG1850	ribulose-bisphosphate carboxylase activity
MMZ59_06525	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MMZ59_06530	COG0235	Class ii aldolase
MMZ59_06535	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MMZ59_06545	COG3852	Histidine kinase
MMZ59_06550	COG1846	Transcriptional regulator
MMZ59_06555	COG1360	Flagellar Motor Protein
MMZ59_06560	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MMZ59_06565	COG0542	response to heat
MMZ59_06570	COG3949	Membrane
MMZ59_06575	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MMZ59_06580	COG0720	synthase
MMZ59_06585	COG0602	queuosine metabolic process
MMZ59_06590	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MMZ59_06605	COG4873	Protein conserved in bacteria
MMZ59_06615	COG3773	Cell wall hydrolase
MMZ59_06620	COG2244	polysaccharide biosynthetic process
MMZ59_06625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MMZ59_06630	COG2217	Heavy metal translocating P-type atpase
MMZ59_06635	COG0006	proline dipeptidase activity
MMZ59_06640	COG1609	Transcriptional regulator
MMZ59_06645	COG3711	transcriptional antiterminator
MMZ59_06650	COG1263	PTS System
MMZ59_06650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MMZ59_06650	COG2190	(PTS) system
MMZ59_06655	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MMZ59_06660	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MMZ59_06670	COG1533	DNA photolyase activity
MMZ59_06675	COG0840	transmembrane signaling receptor activity
MMZ59_06685	COG2084	Dehydrogenase
MMZ59_06690	COG2340	Cysteine-rich secretory protein family
MMZ59_06695	COG0768	penicillin binding
MMZ59_06700	COG4191	Histidine kinase
MMZ59_06705	COG0436	Aminotransferase
MMZ59_06710	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MMZ59_06720	COG1714	RDD family
MMZ59_06730	COG0784	Response regulator, receiver
MMZ59_06730	COG0835	chemotaxis
MMZ59_06740	COG2207	Transcriptional regulator
MMZ59_06740	COG1917	Cupin 2, conserved barrel domain protein
MMZ59_06745	COG0697	spore germination
MMZ59_06760	COG2814	Major facilitator Superfamily
MMZ59_06765	COG1376	ErfK ybiS ycfS ynhG family protein
MMZ59_06770	COG1408	metallophosphoesterase
MMZ59_06775	COG1028	Short-chain dehydrogenase reductase Sdr
MMZ59_06780	COG2200	EAL domain
MMZ59_06785	COG3546	catalase activity
MMZ59_06790	COG4703	Protein of unknown function (DUF1797)
MMZ59_06795	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
MMZ59_06805	COG0517	IMP dehydrogenase activity
MMZ59_06810	COG0583	DNA-binding transcription factor activity
MMZ59_06820	COG0716	FMN binding
MMZ59_06830	COG0716	FMN binding
MMZ59_06835	COG2171	N-acyltransferase activity
MMZ59_06840	COG1473	amidohydrolase
MMZ59_06850	COG0668	transmembrane transport
MMZ59_06855	COG0450	alkyl hydroperoxide reductase
MMZ59_06860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MMZ59_06875	COG0746	molybdenum cofactor guanylyltransferase activity
MMZ59_06880	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MMZ59_06885	COG0303	'Molybdopterin
MMZ59_06890	COG1763	Mo-molybdopterin cofactor biosynthetic process
MMZ59_06895	COG0314	molybdopterin synthase activity
MMZ59_06900	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MMZ59_06915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MMZ59_06920	COG1136	(ABC) transporter
MMZ59_06925	COG0577	efflux transmembrane transporter activity
MMZ59_06930	COG1349	DNA-binding transcription factor activity
MMZ59_06935	COG1105	Belongs to the carbohydrate kinase PfkB family
MMZ59_06940	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MMZ59_06940	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MMZ59_06940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MMZ59_06945	COG0681	Belongs to the peptidase S26 family
MMZ59_06955	COG0488	(ABC) transporter
MMZ59_06960	COG2309	aminopeptidase activity
MMZ59_06970	COG1077	Cell shape determining protein MreB Mrl
MMZ59_06975	COG2002	toxin-antitoxin pair type II binding
MMZ59_06980	COG3852	Histidine kinase
MMZ59_06985	COG2105	PFAM AIG2 family protein
MMZ59_06985	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
MMZ59_06990	COG0569	domain protein
MMZ59_06995	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MMZ59_07000	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MMZ59_07005	COG5503	Protein of unknown function (DUF1447)
MMZ59_07010	COG0561	phosphatase activity
MMZ59_07015	COG0242	peptide deformylase activity
MMZ59_07030	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MMZ59_07035	COG0022	dehydrogenase e1 component
MMZ59_07040	COG0508	dehydrogenase complex catalyzes the overall conversion of
MMZ59_07045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MMZ59_07050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MMZ59_07060	COG1982	Orn Lys Arg decarboxylase major
MMZ59_07065	COG4476	Belongs to the UPF0223 family
MMZ59_07075	COG4493	Belongs to the UPF0637 family
MMZ59_07085	COG0483	inositol monophosphate 1-phosphatase activity
MMZ59_07100	COG1595	DNA-templated transcription, initiation
MMZ59_07120	COG1217	gtp-binding protein TYPA
MMZ59_07130	COG4896	Protein conserved in bacteria
MMZ59_07140	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MMZ59_07145	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MMZ59_07150	COG2066	Belongs to the glutaminase family
MMZ59_07155	COG4838	Belongs to the UPF0358 family
MMZ59_07160	COG0772	Belongs to the SEDS family
MMZ59_07170	COG0415	Belongs to the DNA photolyase family
MMZ59_07175	COG1612	heme a metabolic process
MMZ59_07180	COG0109	protoheme IX farnesyltransferase activity
MMZ59_07185	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MMZ59_07185	COG2010	Cytochrome c
MMZ59_07190	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MMZ59_07195	COG1845	cytochrome c oxidase, subunit III
MMZ59_07200	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MMZ59_07205	COG3336	cytochrome c oxidase
MMZ59_07215	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
MMZ59_07220	COG2340	Cysteine-rich secretory protein family
MMZ59_07240	COG3679	Belongs to the UPF0342 family
MMZ59_07245	COG4471	UPF0298 protein
MMZ59_07250	COG0742	ribosomal rna small subunit methyltransferase
MMZ59_07255	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MMZ59_07260	COG3314	Sporulation integral membrane protein YlbJ
MMZ59_07265	COG1752	Esterase of the alpha-beta hydrolase superfamily
MMZ59_07270	COG3480	Lon protease (S16) C-terminal proteolytic domain
MMZ59_07280	COG1399	metal-binding, possibly nucleic acid-binding protein
MMZ59_07285	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MMZ59_07295	COG0454	-acetyltransferase
MMZ59_07300	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MMZ59_07305	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MMZ59_07310	COG2001	Belongs to the MraZ family
MMZ59_07315	COG0275	rRNA processing
MMZ59_07320	COG4839	cell division protein FtsL
MMZ59_07325	COG0768	penicillin binding
MMZ59_07330	COG0768	penicillin binding
MMZ59_07335	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MMZ59_07340	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MMZ59_07345	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MMZ59_07350	COG0772	Belongs to the SEDS family
MMZ59_07355	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MMZ59_07360	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MMZ59_07365	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MMZ59_07370	COG3879	Bacterial protein of unknown function (DUF881)
MMZ59_07375	COG3879	Bacterial protein of unknown function (DUF881)
MMZ59_07380	COG3856	small basic protein
MMZ59_07385	COG0849	cell division
MMZ59_07390	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MMZ59_07395	COG1404	Belongs to the peptidase S8 family
MMZ59_07395	COG4412	M6 family metalloprotease domain protein
MMZ59_07405	COG1191	sigma factor activity
MMZ59_07410	COG1191	sigma factor activity
MMZ59_07415	COG2390	Transcriptional regulator
MMZ59_07430	COG3730	PTS system glucitol sorbitol-specific
MMZ59_07435	COG3732	PTS system glucitol sorbitol-specific
MMZ59_07445	COG1119	ATPase activity
MMZ59_07450	COG1873	PFAM PRC-barrel domain
MMZ59_07455	COG1496	oxidoreductase activity
MMZ59_07460	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MMZ59_07465	COG1799	cell septum assembly
MMZ59_07470	COG0762	integral membrane protein
MMZ59_07475	COG2302	S4 RNA-binding domain
MMZ59_07480	COG3599	regulation of cell shape
MMZ59_07485	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MMZ59_07490	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MMZ59_07495	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MMZ59_07500	COG0564	pseudouridine synthase activity
MMZ59_07505	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MMZ59_07510	COG2233	PERMEase
MMZ59_07515	COG0540	Belongs to the ATCase OTCase family
MMZ59_07520	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MMZ59_07525	COG0505	Belongs to the CarA family
MMZ59_07530	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MMZ59_07535	COG0543	2 iron, 2 sulfur cluster binding
MMZ59_07540	COG0167	dihydroorotate dehydrogenase activity
MMZ59_07545	COG0284	orotidine-5'-phosphate decarboxylase activity
MMZ59_07550	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MMZ59_07560	COG0175	sulfate reduction
MMZ59_07565	COG0306	phosphate transporter
MMZ59_07570	COG2046	Belongs to the sulfate adenylyltransferase family
MMZ59_07575	COG0529	Catalyzes the synthesis of activated sulfate
MMZ59_07580	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MMZ59_07585	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
MMZ59_07590	COG1648	precorrin-2 dehydrogenase activity
MMZ59_07600	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MMZ59_07605	COG1561	YicC-like family, N-terminal region
MMZ59_07610	COG2052	Domain of unknown function (DUF370)
MMZ59_07615	COG0194	GDP metabolic process
MMZ59_07620	COG1758	RNA polymerase activity
MMZ59_07625	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MMZ59_07630	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MMZ59_07635	COG0242	peptide deformylase activity
MMZ59_07640	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MMZ59_07645	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MMZ59_07645	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MMZ59_07650	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MMZ59_07655	COG0631	protein serine/threonine phosphatase activity
MMZ59_07660	COG0515	serine threonine protein kinase
MMZ59_07660	COG2815	serine threonine protein kinase
MMZ59_07665	COG1162	GTPase activity
MMZ59_07670	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MMZ59_07675	COG1564	THIamine pyrophosphokinase
MMZ59_07685	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MMZ59_07690	COG1302	Protein conserved in bacteria
MMZ59_07695	COG1461	Dihydroxyacetone kinase
MMZ59_07700	COG1760	l-serine dehydratase
MMZ59_07705	COG1760	l-serine dehydratase
MMZ59_07710	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MMZ59_07715	COG1349	DNA-binding transcription factor activity
MMZ59_07720	COG0416	fatty acid biosynthetic process
MMZ59_07725	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MMZ59_07730	COG1028	Short-chain dehydrogenase reductase Sdr
MMZ59_07735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MMZ59_07745	COG1196	nuclear chromosome segregation
MMZ59_07750	COG0552	protein localization to endoplasmic reticulum
MMZ59_07755	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MMZ59_07760	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MMZ59_07765	COG0228	four-way junction DNA binding
MMZ59_07770	COG1837	Belongs to the UPF0109 family
MMZ59_07780	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MMZ59_07785	COG0336	Belongs to the RNA methyltransferase TrmD family
MMZ59_07790	COG0335	large ribosomal subunit rRNA binding
MMZ59_07795	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MMZ59_07800	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MMZ59_07810	COG2257	FlhB HrpN YscU SpaS Family
MMZ59_07815	COG0045	succinate-CoA ligase (ADP-forming) activity
MMZ59_07820	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MMZ59_07825	COG0758	DNA mediated transformation
MMZ59_07830	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MMZ59_07835	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MMZ59_07840	COG4974	Belongs to the 'phage' integrase family
MMZ59_07845	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MMZ59_07850	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MMZ59_07855	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MMZ59_07860	COG1815	bacterial-type flagellum-dependent cell motility
MMZ59_07865	COG1558	bacterial-type flagellum-dependent cell motility
MMZ59_07870	COG1677	Flagellar hook-basal body complex protein FliE
MMZ59_07875	COG1766	The M ring may be actively involved in energy transduction
MMZ59_07880	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MMZ59_07885	COG1317	bacterial-type flagellum organization
MMZ59_07890	COG1157	protein secretion by the type III secretion system
MMZ59_07895	COG2882	bacterial-type flagellum organization
MMZ59_07900	COG3334	PFAM MgtE intracellular
MMZ59_07905	COG3144	bacterial-type flagellum assembly
MMZ59_07910	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
MMZ59_07915	COG4786	Flagellar basal body rod
MMZ59_07920	COG1582	Flagellar protein (FlbD)
MMZ59_07925	COG1580	Controls the rotational direction of flagella during chemotaxis
MMZ59_07930	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MMZ59_07935	COG1776	CheC inhibitor of MCP methylation
MMZ59_07935	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MMZ59_07940	COG2201	protein-glutamate methylesterase activity
MMZ59_07945	COG3190	flagellar
MMZ59_07950	COG1338	Plays a role in the flagellum-specific transport system
MMZ59_07955	COG1987	bacterial-type flagellum assembly
MMZ59_07960	COG1684	flagellar biosynthetic protein fliR
MMZ59_07965	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MMZ59_07970	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MMZ59_07975	COG1419	protein localization to endoplasmic reticulum
MMZ59_07980	COG0455	bacterial-type flagellum organization
MMZ59_07985	COG2201	protein-glutamate methylesterase activity
MMZ59_07990	COG0643	Histidine kinase
MMZ59_07990	COG2198	Histidine kinase
MMZ59_07995	COG0835	chemotaxis
MMZ59_08000	COG1776	CheC inhibitor of MCP methylation
MMZ59_08010	COG1191	sigma factor activity
MMZ59_08025	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MMZ59_08030	COG0528	UMP kinase activity
MMZ59_08035	COG0233	cytoplasmic translational termination
MMZ59_08040	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MMZ59_08045	COG4589	Belongs to the CDS family
MMZ59_08050	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MMZ59_08055	COG0750	zinc metalloprotease
MMZ59_08060	COG0442	prolyl-tRNA aminoacylation
MMZ59_08065	COG2176	DNA-directed DNA polymerase activity
MMZ59_08080	COG3693	PFAM glycoside hydrolase, family 10
MMZ59_08090	COG0779	Required for maturation of 30S ribosomal subunits
MMZ59_08095	COG0195	Participates in both transcription termination and antitermination
MMZ59_08100	COG2740	Nucleic-acid-binding protein implicated in transcription termination
MMZ59_08105	COG1358	cellular component organization or biogenesis
MMZ59_08110	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MMZ59_08115	COG1550	Protein conserved in bacteria
MMZ59_08120	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MMZ59_08125	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MMZ59_08130	COG0196	riboflavin kinase activity
MMZ59_08135	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MMZ59_08140	COG1185	polyribonucleotide nucleotidyltransferase activity
MMZ59_08145	COG0726	polysaccharide deacetylase
MMZ59_08150	COG0612	Peptidase, M16
MMZ59_08160	COG1873	PFAM PRC-barrel domain
MMZ59_08165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MMZ59_08170	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MMZ59_08175	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MMZ59_08180	COG0527	aspartate kinase activity
MMZ59_08190	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MMZ59_08195	COG0740	serine-type endopeptidase activity
MMZ59_08205	COG1674	ftsk spoiiie
MMZ59_08205	COG4980	gas vesicle protein
MMZ59_08210	COG2188	Transcriptional regulator
MMZ59_08215	COG2814	Major facilitator Superfamily
MMZ59_08220	COG2409	Drug exporters of the RND superfamily
MMZ59_08220	COG1033	growth of symbiont in host cell
MMZ59_08225	COG0612	Peptidase, M16
MMZ59_08230	COG0612	Peptidase, M16
MMZ59_08240	COG1033	growth of symbiont in host cell
MMZ59_08240	COG2409	Drug exporters of the RND superfamily
MMZ59_08245	COG0300	oxidoreductase activity
MMZ59_08260	COG1426	Protein conserved in bacteria
MMZ59_08265	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MMZ59_08270	COG1058	Belongs to the CinA family
MMZ59_08270	COG1546	Belongs to the CinA family
MMZ59_08275	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MMZ59_08280	COG1418	mRNA catabolic process
MMZ59_08285	COG1692	metallophosphoesterase
MMZ59_08290	COG2359	stage V sporulation protein S
MMZ59_08295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MMZ59_08300	COG1063	alcohol dehydrogenase
MMZ59_08305	COG0156	8-amino-7-oxononanoate synthase activity
MMZ59_08310	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MMZ59_08315	COG4550	Control of competence regulator ComK, YlbF/YmcA
MMZ59_08335	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MMZ59_08340	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MMZ59_08360	COG1329	Transcriptional regulator
MMZ59_08365	COG4195	phage-related replication protein
MMZ59_08370	COG0457	Tetratricopeptide repeat
MMZ59_08375	COG1404	Belongs to the peptidase S8 family
MMZ59_08380	COG4195	phage-related replication protein
MMZ59_08385	COG1764	response to oxidative stress
MMZ59_08390	COG2076	Multidrug Resistance protein
MMZ59_08415	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MMZ59_08420	COG1923	regulation of RNA biosynthetic process
MMZ59_08435	COG1780	Probably involved in ribonucleotide reductase function
MMZ59_08440	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MMZ59_08445	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MMZ59_08450	COG4112	unkown
MMZ59_08460	COG0464	growth
MMZ59_08465	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MMZ59_08470	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
MMZ59_08475	COG0789	Transcriptional regulator
MMZ59_08480	COG0174	glutamine synthetase
MMZ59_08515	COG0457	Tetratricopeptide repeat
MMZ59_08530	COG5444	nuclease activity
MMZ59_08555	COG5646	InterPro IPR014922
MMZ59_08575	COG0457	Tetratricopeptide repeat
MMZ59_08585	COG3619	membrane
MMZ59_08590	COG1793	dna ligase
MMZ59_08590	COG3285	dna ligase
MMZ59_08595	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MMZ59_08610	COG1959	2 iron, 2 sulfur cluster binding
MMZ59_08615	COG0702	epimerase
MMZ59_08625	COG0247	lactate metabolic process
MMZ59_08630	COG1139	Iron-sulfur cluster binding protein
MMZ59_08635	COG1556	Lactate utilization protein
MMZ59_08655	COG2323	membrane
MMZ59_08660	COG1309	transcriptional regulator
MMZ59_08665	COG2124	cytochrome p450
MMZ59_08665	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MMZ59_08670	COG3591	Belongs to the peptidase S1B family
MMZ59_08675	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MMZ59_08680	COG3209	COG3209 Rhs family protein
MMZ59_08685	COG1366	Belongs to the anti-sigma-factor antagonist family
MMZ59_08700	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MMZ59_08705	COG1388	LysM domain
MMZ59_08710	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MMZ59_08715	COG4224	UPF0291 protein
MMZ59_08720	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MMZ59_08730	COG3763	UPF0154 protein
MMZ59_08740	COG0785	Cytochrome C biogenesis protein
MMZ59_08745	COG4846	Membrane protein involved in cytochrome C biogenesis
MMZ59_08755	COG0071	Belongs to the small heat shock protein (HSP20) family
MMZ59_08770	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MMZ59_08775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MMZ59_08795	COG0824	Thioesterase
MMZ59_08805	COG4841	protein insertion into membrane
MMZ59_08810	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MMZ59_08815	COG1832	CoA-binding protein
MMZ59_08820	COG0187	DNA topoisomerase II activity
MMZ59_08825	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MMZ59_08835	COG0738	Major facilitator superfamily
MMZ59_08840	COG0473	3-isopropylmalate dehydrogenase activity
MMZ59_08845	COG0110	maltose O-acetyltransferase activity
MMZ59_08850	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MMZ59_08855	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MMZ59_08860	COG0640	Transcriptional regulator
MMZ59_08870	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MMZ59_08875	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MMZ59_08885	COG1309	transcriptional regulator
MMZ59_08890	COG2249	NAD(P)H dehydrogenase (quinone) activity
MMZ59_08895	COG1733	regulation of RNA biosynthetic process
MMZ59_08900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MMZ59_08905	COG0251	oxidation-reduction process
MMZ59_08935	COG0657	acetylesterase activity
MMZ59_08945	COG2723	6-phospho-beta-galactosidase activity
MMZ59_08950	COG1263	PTS System
MMZ59_08950	COG2190	(PTS) system
MMZ59_08950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MMZ59_08965	COG2205	protein histidine kinase activity
MMZ59_08970	COG0745	RESPONSE REGULATOR receiver
MMZ59_08980	COG3507	Belongs to the glycosyl hydrolase 43 family
MMZ59_08985	COG1012	belongs to the aldehyde dehydrogenase family
MMZ59_08990	COG1486	melibiose metabolic process
MMZ59_08995	COG0395	ABC-type sugar transport system, permease component
MMZ59_09000	COG1175	transmembrane transport
MMZ59_09005	COG1653	transport
MMZ59_09010	COG1609	Transcriptional regulator
MMZ59_09015	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MMZ59_09030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MMZ59_09035	COG0456	acetyltransferase
MMZ59_09040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MMZ59_09070	COG1846	Transcriptional regulator
MMZ59_09075	COG2814	Major facilitator Superfamily
MMZ59_09085	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MMZ59_09085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MMZ59_09085	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MMZ59_09090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MMZ59_09090	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MMZ59_09090	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MMZ59_09095	COG1105	Belongs to the carbohydrate kinase PfkB family
MMZ59_09105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MMZ59_09125	COG1012	belongs to the aldehyde dehydrogenase family
MMZ59_09130	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MMZ59_09135	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MMZ59_09145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MMZ59_09150	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MMZ59_09155	COG1024	Enoyl-CoA hydratase
MMZ59_09160	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MMZ59_09165	COG0511	ligase activity, forming carbon-carbon bonds
MMZ59_09170	COG0439	Biotin carboxylase
MMZ59_09175	COG0318	PFAM AMP-dependent synthetase and ligase
MMZ59_09180	COG1960	acyl-CoA dehydrogenase activity
MMZ59_09185	COG1649	PFAM Uncharacterised BCR, COG1649
MMZ59_09190	COG2365	Tyrosine phosphatase family
MMZ59_09195	COG1349	DNA-binding transcription factor activity
MMZ59_09200	COG1942	4-Oxalocrotonate Tautomerase
MMZ59_09210	COG3835	regulator
MMZ59_09215	COG0277	FAD linked oxidase domain protein
MMZ59_09220	COG0247	lactate metabolic process
MMZ59_09240	COG0166	Belongs to the GPI family
MMZ59_09245	COG2246	polysaccharide biosynthetic process
MMZ59_09250	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MMZ59_09255	COG0586	Pfam SNARE associated Golgi protein
MMZ59_09260	COG1587	Uroporphyrinogen-III synthase
MMZ59_09270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MMZ59_09285	COG0534	Mate efflux family protein
MMZ59_09290	COG2027	D-alanyl-D-alanine carboxypeptidase
MMZ59_09295	COG4677	pectinesterase activity
MMZ59_09300	COG2323	membrane
MMZ59_09305	COG2146	nitrite reductase [NAD(P)H] activity
MMZ59_09310	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MMZ59_09315	COG0243	molybdopterin cofactor binding
MMZ59_09320	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MMZ59_09325	COG2223	nitrite transmembrane transporter activity
MMZ59_09330	COG0493	'glutamate synthase
MMZ59_09335	COG0070	glutamate synthase
MMZ59_09335	COG0069	glutamate synthase activity
MMZ59_09335	COG0067	glutamate synthase
MMZ59_09340	COG0583	DNA-binding transcription factor activity
MMZ59_09350	COG1132	(ABC) transporter
MMZ59_09355	COG0789	Transcriptional regulator
MMZ59_09355	COG4978	Transcriptional regulator
MMZ59_09360	COG0454	-acetyltransferase
MMZ59_09365	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MMZ59_09370	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MMZ59_09375	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MMZ59_09385	COG0243	molybdopterin cofactor binding
MMZ59_09395	COG1070	Carbohydrate kinase
MMZ59_09400	COG2115	Belongs to the xylose isomerase family
MMZ59_09405	COG1940	carbohydrate kinase activity
MMZ59_09415	COG2211	Major facilitator Superfamily
MMZ59_09420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MMZ59_09425	COG1994	Peptidase M50
MMZ59_09445	COG1309	transcriptional regulator
MMZ59_09450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MMZ59_09455	COG3708	Transcriptional regulator
MMZ59_09460	COG2378	regulation of single-species biofilm formation
MMZ59_09470	COG0640	Transcriptional regulator
MMZ59_09475	COG0531	amino acid
MMZ59_09480	COG0741	lytic transglycosylase activity
MMZ59_09485	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MMZ59_09490	COG2079	MmgE PrpD family protein
MMZ59_09495	COG0372	Belongs to the citrate synthase family
MMZ59_09500	COG2322	membrane
MMZ59_09510	COG1388	LysM domain
MMZ59_09510	COG3584	3D domain protein
MMZ59_09515	COG0514	ATP-dependent DNA helicase (RecQ)
MMZ59_09525	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MMZ59_09550	COG1012	belongs to the aldehyde dehydrogenase family
MMZ59_09555	COG1657	PFAM Prenyltransferase squalene oxidase
MMZ59_09560	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MMZ59_09565	COG0385	Bile acid
MMZ59_09570	COG0508	dehydrogenase complex catalyzes the overall conversion of
MMZ59_09575	COG0567	Dehydrogenase, E1 component
MMZ59_09580	COG4548	von Willebrand factor, type A
MMZ59_09585	COG0714	Associated with various cellular activities
MMZ59_09590	COG2032	superoxide dismutase activity
MMZ59_09595	COG0791	NLP P60 protein
MMZ59_09595	COG1388	LysM domain
MMZ59_09600	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MMZ59_09605	COG0534	Mate efflux family protein
MMZ59_09610	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MMZ59_09615	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MMZ59_09625	COG2962	Rard protein
MMZ59_09640	COG1733	regulation of RNA biosynthetic process
MMZ59_09645	COG0778	Nitroreductase
MMZ59_09655	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MMZ59_09660	COG0793	Belongs to the peptidase S41A family
MMZ59_09660	COG3409	Peptidoglycan-binding domain 1 protein
MMZ59_09665	COG2226	methyltransferase
MMZ59_09675	COG1876	peptidase activity
MMZ59_09680	COG0813	purine-nucleoside phosphorylase activity
MMZ59_09690	COG0671	phosphoesterase, PA-phosphatase related
MMZ59_09705	COG4479	Belongs to the UPF0346 family
MMZ59_09715	COG1509	lysine 2,3-aminomutase activity
MMZ59_09720	COG3829	transcription factor binding
MMZ59_09725	COG0463	Glycosyl transferase, family 2
MMZ59_09740	COG4641	Protein conserved in bacteria
MMZ59_09750	COG1086	Polysaccharide biosynthesis protein
MMZ59_09755	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MMZ59_09760	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MMZ59_09765	COG1846	Transcriptional regulator
MMZ59_09785	COG4698	Protein conserved in bacteria
MMZ59_09790	COG2755	lipolytic protein G-D-S-L family
MMZ59_09795	COG1999	signal sequence binding
MMZ59_09810	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MMZ59_09815	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MMZ59_09820	COG1272	protein, Hemolysin III
MMZ59_09825	COG0204	Acyl-transferase
MMZ59_09830	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MMZ59_09835	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MMZ59_09840	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MMZ59_09850	COG2136	Putative SAM-dependent methyltransferase
MMZ59_09850	COG2521	methyltransferase
MMZ59_09860	COG0129	dihydroxy-acid dehydratase activity
MMZ59_09865	COG1413	lyase activity
MMZ59_09870	COG1418	mRNA catabolic process
MMZ59_09875	COG0386	Belongs to the glutathione peroxidase family
MMZ59_09880	COG2759	Belongs to the formate--tetrahydrofolate ligase family
MMZ59_09885	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
MMZ59_09890	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MMZ59_09900	COG1278	Cold shock
MMZ59_09915	COG0328	RNA-DNA hybrid ribonuclease activity
MMZ59_09920	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MMZ59_09925	COG0328	RNA-DNA hybrid ribonuclease activity
MMZ59_09935	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MMZ59_09945	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MMZ59_09950	COG1755	Isoprenylcysteine carboxyl methyltransferase
MMZ59_09955	COG3424	synthase
MMZ59_09960	COG0456	acetyltransferase
MMZ59_09960	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MMZ59_09965	COG0726	polysaccharide deacetylase
MMZ59_09970	COG2233	PERMEase
MMZ59_09975	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MMZ59_09980	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MMZ59_09985	COG1199	ATP-dependent helicase activity
MMZ59_09995	COG0116	Belongs to the methyltransferase superfamily
MMZ59_10005	COG3599	regulation of cell shape
MMZ59_10010	COG4474	Belongs to the UPF0398 family
MMZ59_10020	COG3359	exonuclease
MMZ59_10025	COG1205	dead DEAH box helicase
MMZ59_10025	COG1111	helicase
MMZ59_10030	COG1902	pentaerythritol trinitrate reductase activity
MMZ59_10035	COG2190	(PTS) system
MMZ59_10040	COG0071	Belongs to the small heat shock protein (HSP20) family
MMZ59_10070	COG3331	DNA recombination
MMZ59_10075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MMZ59_10075	COG4499	WXG100 protein secretion system (Wss), protein YukC
MMZ59_10085	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MMZ59_10090	COG3935	DnaD domain protein
MMZ59_10095	COG0017	Asparaginyl-tRNA synthetase
MMZ59_10100	COG5353	protein conserved in bacteria
MMZ59_10110	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MMZ59_10110	COG1199	ATP-dependent helicase activity
MMZ59_10115	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MMZ59_10120	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MMZ59_10125	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MMZ59_10135	COG0617	tRNA 3'-terminal CCA addition
MMZ59_10140	COG0438	transferase activity, transferring glycosyl groups
MMZ59_10145	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MMZ59_10150	COG1803	Methylglyoxal synthase
MMZ59_10155	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MMZ59_10160	COG1694	Mazg nucleotide pyrophosphohydrolase
MMZ59_10165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MMZ59_10175	COG4347	Protein of unknown function (DUF1405)
MMZ59_10180	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MMZ59_10180	COG2010	Cytochrome c
MMZ59_10185	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MMZ59_10190	COG0723	plastoquinol--plastocyanin reductase activity
MMZ59_10200	COG5582	Belongs to the UPF0302 family
MMZ59_10205	COG0457	Tetratricopeptide repeat
MMZ59_10210	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MMZ59_10215	COG0287	Prephenate dehydrogenase
MMZ59_10220	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MMZ59_10225	COG0159	tryptophan synthase activity
MMZ59_10230	COG0133	tryptophan synthase activity
MMZ59_10235	COG0135	phosphoribosylanthranilate isomerase activity
MMZ59_10240	COG0134	indole-3-glycerol-phosphate synthase activity
MMZ59_10245	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MMZ59_10255	COG4401	Chorismate mutase type I
MMZ59_10260	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MMZ59_10265	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MMZ59_10270	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MMZ59_10275	COG0105	UTP biosynthetic process
MMZ59_10280	COG0142	geranyltranstransferase activity
MMZ59_10285	COG2226	methyltransferase
MMZ59_10290	COG0142	geranyltranstransferase activity
MMZ59_10300	COG0302	gtp cyclohydrolase
MMZ59_10305	COG0776	regulation of translation
MMZ59_10310	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MMZ59_10325	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MMZ59_10330	COG1160	GTP binding
MMZ59_10355	COG1304	FMN binding
MMZ59_10360	COG0539	negative regulation of cytoplasmic translation
MMZ59_10365	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MMZ59_10375	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
MMZ59_10380	COG2959	enzyme of heme biosynthesis
MMZ59_10385	COG3409	Peptidoglycan-binding domain 1 protein
MMZ59_10385	COG3773	Cell wall hydrolase
MMZ59_10390	COG2339	peptidase activity
MMZ59_10395	COG0492	ferredoxin-NADP+ reductase activity
MMZ59_10400	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MMZ59_10405	COG4862	establishment of competence for transformation
MMZ59_10410	COG1408	metallophosphoesterase
MMZ59_10420	COG1388	LysM domain
MMZ59_10425	COG1266	CAAX protease self-immunity
MMZ59_10430	COG0514	ATP-dependent DNA helicase (RecQ)
MMZ59_10435	COG4955	Helix-turn-helix domain
MMZ59_10440	COG1141	Ferredoxin
MMZ59_10445	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MMZ59_10450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MMZ59_10465	COG1595	DNA-templated transcription, initiation
MMZ59_10470	COG5002	protein histidine kinase activity
MMZ59_10475	COG0745	RESPONSE REGULATOR receiver
MMZ59_10480	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MMZ59_10485	COG1333	cytochrome c biogenesis protein
MMZ59_10490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MMZ59_10495	COG1187	pseudouridine synthase activity
MMZ59_10500	COG0700	Nucleoside recognition
MMZ59_10505	COG2715	membrane protein required for spore maturation
MMZ59_10510	COG1686	Belongs to the peptidase S11 family
MMZ59_10520	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MMZ59_10525	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MMZ59_10535	COG1547	Domain of unknown function (DUF309)
MMZ59_10540	COG0456	acetyltransferase
MMZ59_10545	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MMZ59_10555	COG0307	riboflavin synthase, alpha
MMZ59_10575	COG2814	Major facilitator Superfamily
MMZ59_10580	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MMZ59_10585	COG4086	secreted protein
MMZ59_10590	COG0019	diaminopimelate decarboxylase activity
MMZ59_10595	COG0697	spore germination
MMZ59_10610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MMZ59_10630	COG1191	sigma factor activity
MMZ59_10635	COG2172	sigma factor antagonist activity
MMZ59_10645	COG1686	Belongs to the peptidase S11 family
MMZ59_10650	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MMZ59_10655	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MMZ59_10660	COG4974	Belongs to the 'phage' integrase family
MMZ59_10670	COG0735	belongs to the Fur family
MMZ59_10675	COG1300	Membrane
MMZ59_10680	COG1404	Belongs to the peptidase S8 family
MMZ59_10690	COG2153	protein acetylation
MMZ59_10695	COG1379	DNA repair
MMZ59_10700	COG0494	nUDIX hydrolase
MMZ59_10705	COG0667	Aldo Keto reductase
MMZ59_10720	COG1073	alpha beta
MMZ59_10725	COG0457	Tetratricopeptide repeat
MMZ59_10735	COG4918	Iron-sulphur cluster biosynthesis
MMZ59_10740	COG4305	rare lipoprotein A
MMZ59_10745	COG0456	acetyltransferase
MMZ59_10745	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MMZ59_10750	COG0456	acetyltransferase
MMZ59_10760	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MMZ59_10770	COG2211	Major facilitator Superfamily
MMZ59_10775	COG1072	(Pantothenic acid kinase))
MMZ59_10780	COG0446	pyridine nucleotide-disulphide oxidoreductase
MMZ59_10790	COG0300	oxidoreductase activity
MMZ59_10795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MMZ59_10800	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MMZ59_10820	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MMZ59_10825	COG4187	Peptidase family M20/M25/M40
MMZ59_10830	COG1902	pentaerythritol trinitrate reductase activity
MMZ59_10835	COG0596	Alpha beta hydrolase
MMZ59_10840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MMZ59_10850	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MMZ59_10855	COG2188	Transcriptional regulator
MMZ59_10860	COG2723	6-phospho-beta-galactosidase activity
MMZ59_10865	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MMZ59_10870	COG1447	Phosphotransferase system cellobiose-specific component IIA
MMZ59_10875	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MMZ59_10885	COG1028	Short-chain dehydrogenase reductase Sdr
MMZ59_10895	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MMZ59_10900	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MMZ59_10910	COG0706	membrane insertase activity
MMZ59_10915	COG0835	chemotaxis
MMZ59_10920	COG2195	Cleaves the N-terminal amino acid of tripeptides
MMZ59_10925	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MMZ59_10930	COG0346	lactoylglutathione lyase activity
MMZ59_10940	COG1376	ErfK ybiS ycfS ynhG family protein
MMZ59_10945	COG4129	membrane
MMZ59_10950	COG1126	abc transporter atp-binding protein
MMZ59_10955	COG0765	amino acid transport
MMZ59_10960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MMZ59_10970	COG1597	lipid kinase activity
MMZ59_10980	COG0508	dehydrogenase complex catalyzes the overall conversion of
MMZ59_10985	COG0022	dehydrogenase e1 component
MMZ59_10990	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MMZ59_10995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MMZ59_11000	COG3426	butyrate kinase activity
MMZ59_11005	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MMZ59_11010	COG0280	phosphate acetyltransferase
MMZ59_11015	COG3829	transcription factor binding
MMZ59_11015	COG3290	protein histidine kinase activity
MMZ59_11025	COG0584	glycerophosphoryl diester phosphodiesterase
MMZ59_11030	COG0457	Tetratricopeptide repeat
MMZ59_11035	COG0745	RESPONSE REGULATOR receiver
MMZ59_11040	COG0750	zinc metalloprotease
MMZ59_11045	COG0497	DNA recombination
MMZ59_11050	COG1438	arginine binding
MMZ59_11055	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
MMZ59_11060	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MMZ59_11065	COG0142	geranyltranstransferase activity
MMZ59_11070	COG1722	exodeoxyribonuclease VII activity
MMZ59_11075	COG1570	exodeoxyribonuclease VII activity
MMZ59_11080	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MMZ59_11085	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MMZ59_11090	COG1302	Protein conserved in bacteria
MMZ59_11095	COG0439	Biotin carboxylase
MMZ59_11100	COG0511	ligase activity, forming carbon-carbon bonds
MMZ59_11140	COG3854	ATPases associated with a variety of cellular activities
MMZ59_11150	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MMZ59_11155	COG0006	proline dipeptidase activity
MMZ59_11160	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MMZ59_11170	COG3872	metal-dependent enzyme
MMZ59_11180	COG1752	Esterase of the alpha-beta hydrolase superfamily
MMZ59_11185	COG1321	iron dependent repressor
MMZ59_11190	COG0095	Lipoate-protein ligase
MMZ59_11195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MMZ59_11200	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MMZ59_11205	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MMZ59_11210	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MMZ59_11215	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MMZ59_11240	COG0681	Belongs to the peptidase S26 family
MMZ59_11275	COG4970	Tfp pilus assembly protein FimT
MMZ59_11280	COG4537	Required for transformation and DNA binding
MMZ59_11285	COG1459	type II secretion system
MMZ59_11290	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MMZ59_11295	COG1366	Belongs to the anti-sigma-factor antagonist family
MMZ59_11305	COG1393	Belongs to the ArsC family
MMZ59_11315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MMZ59_11325	COG0011	TIGRFAM Protein of
MMZ59_11330	COG2814	Major facilitator Superfamily
MMZ59_11335	COG2866	Carboxypeptidase
MMZ59_11340	COG1368	sulfuric ester hydrolase activity
MMZ59_11345	COG1940	carbohydrate kinase activity
MMZ59_11350	COG4483	Protein conserved in bacteria
MMZ59_11355	COG0457	Tetratricopeptide repeat
MMZ59_11355	COG0705	Rhomboid family
MMZ59_11370	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MMZ59_11375	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MMZ59_11385	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MMZ59_11390	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MMZ59_11395	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MMZ59_11400	COG0581	inorganic phosphate transmembrane transporter activity
MMZ59_11405	COG0573	inorganic phosphate transmembrane transporter activity
MMZ59_11410	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MMZ59_11415	COG0768	penicillin binding
MMZ59_11420	COG0477	Major facilitator Superfamily
MMZ59_11425	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MMZ59_11430	COG2839	Protein conserved in bacteria
MMZ59_11435	COG5521	maltodextrose utilization protein MalA
MMZ59_11440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MMZ59_11445	COG1388	LysM domain
MMZ59_11450	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MMZ59_11455	COG4709	membrane
MMZ59_11460	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
MMZ59_11465	COG1940	carbohydrate kinase activity
MMZ59_11470	COG0735	belongs to the Fur family
MMZ59_11475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MMZ59_11480	COG1121	(ABC) transporter
MMZ59_11485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MMZ59_11500	COG0513	Belongs to the DEAD box helicase family
MMZ59_11510	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MMZ59_11515	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MMZ59_11520	COG2384	SAM-dependent methyltransferase
MMZ59_11525	COG2010	Cytochrome c
MMZ59_11530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MMZ59_11535	COG0358	DNA primase activity
MMZ59_11540	COG1671	Belongs to the UPF0178 family
MMZ59_11545	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MMZ59_11550	COG0517	IMP dehydrogenase activity
MMZ59_11555	COG0751	glycine-tRNA ligase activity
MMZ59_11560	COG0752	glycyl-tRNA synthetase alpha subunit
MMZ59_11565	COG1381	Involved in DNA repair and RecF pathway recombination
MMZ59_11575	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MMZ59_11580	COG0295	cytidine deaminase activity
MMZ59_11585	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MMZ59_11590	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MMZ59_11595	COG1480	7TM receptor with intracellular HD hydrolase
MMZ59_11600	COG1702	phosphate starvation-inducible protein PhoH
MMZ59_11605	COG0561	phosphatase activity
MMZ59_11620	COG4864	UPF0365 protein
MMZ59_11625	COG1030	water channel activity
MMZ59_11630	COG1610	YqeY-like protein
MMZ59_11640	COG1283	sodium-dependent phosphate transmembrane transporter activity
MMZ59_11645	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MMZ59_11650	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MMZ59_11655	COG2264	protein methyltransferase activity
MMZ59_11660	COG0484	heat shock protein binding
MMZ59_11665	COG0443	Heat shock 70 kDa protein
MMZ59_11670	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MMZ59_11675	COG1420	regulation of RNA biosynthetic process
MMZ59_11680	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MMZ59_11685	COG0481	GTPase activity
MMZ59_11695	COG0860	N-Acetylmuramoyl-L-alanine amidase
MMZ59_11700	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MMZ59_11705	COG0268	Binds directly to 16S ribosomal RNA
MMZ59_11710	COG1466	dna polymerase III delta subunit
MMZ59_11720	COG0658	competence protein
MMZ59_11720	COG2333	competence protein COMEC
MMZ59_11725	COG2131	deaminase
MMZ59_11730	COG1555	photosystem II stabilization
MMZ59_11730	COG1596	polysaccharide export
MMZ59_11735	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MMZ59_11740	COG2226	methyltransferase
MMZ59_11745	COG0799	negative regulation of ribosome biogenesis
MMZ59_11750	COG1713	HD superfamily hydrolase involved in NAD metabolism
MMZ59_11755	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MMZ59_11760	COG1534	Rna-binding protein
MMZ59_11765	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MMZ59_11770	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MMZ59_11775	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
MMZ59_11790	COG2755	lipolytic protein G-D-S-L family
MMZ59_11800	COG0457	Tetratricopeptide repeat
MMZ59_11820	COG2186	Transcriptional regulator
MMZ59_11835	COG1028	Short-chain dehydrogenase reductase Sdr
MMZ59_11840	COG3958	Transketolase
MMZ59_11845	COG3959	Transketolase, thiamine diphosphate binding domain
MMZ59_11865	COG0726	polysaccharide deacetylase
MMZ59_11900	COG1131	(ABC) transporter
MMZ59_11925	COG2160	L-arabinose isomerase activity
MMZ59_11940	COG1609	Transcriptional regulator
MMZ59_11950	COG1846	Transcriptional regulator
MMZ59_11960	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MMZ59_11965	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
MMZ59_11970	COG1733	regulation of RNA biosynthetic process
MMZ59_11975	COG0657	acetylesterase activity
MMZ59_12000	COG2602	Beta-lactamase
MMZ59_12005	COG1960	acyl-CoA dehydrogenase activity
MMZ59_12010	COG1126	abc transporter atp-binding protein
MMZ59_12015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MMZ59_12020	COG0765	amino acid transport
MMZ59_12030	COG1063	alcohol dehydrogenase
MMZ59_12040	COG1028	Short-chain dehydrogenase reductase Sdr
MMZ59_12050	COG1115	amino acid carrier protein
MMZ59_12055	COG0583	DNA-binding transcription factor activity
MMZ59_12060	COG0842	Transport permease protein
MMZ59_12065	COG1511	domain protein
MMZ59_12065	COG0842	Transport permease protein
MMZ59_12070	COG1131	(ABC) transporter
MMZ59_12075	COG1063	alcohol dehydrogenase
MMZ59_12080	COG2226	methyltransferase
MMZ59_12105	COG0626	cystathionine gamma-synthase activity
MMZ59_12110	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MMZ59_12115	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MMZ59_12120	COG2226	methyltransferase
MMZ59_12135	COG0768	penicillin binding
MMZ59_12140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MMZ59_12145	COG0572	uridine kinase
MMZ59_12150	COG0826	peptidase U32
MMZ59_12155	COG0826	peptidase U32
MMZ59_12160	COG4122	O-methyltransferase activity
MMZ59_12165	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MMZ59_12170	COG0183	Belongs to the thiolase family
MMZ59_12175	COG0318	PFAM AMP-dependent synthetase and ligase
MMZ59_12180	COG1268	BioY protein
MMZ59_12185	COG3906	Belongs to the UPF0473 family
MMZ59_12190	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MMZ59_12195	COG4472	Bacterial protein of unknown function (DUF965)
MMZ59_12200	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MMZ59_12205	COG0628	permease
MMZ59_12210	COG1126	abc transporter atp-binding protein
MMZ59_12215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MMZ59_12220	COG0765	amino acid transport
MMZ59_12225	COG0765	amino acid transport
MMZ59_12240	COG3881	PFAM PRC-barrel domain
MMZ59_12245	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MMZ59_12250	COG0457	Tetratricopeptide repeat
MMZ59_12255	COG0482	sulfurtransferase activity
MMZ59_12260	COG1104	cysteine desulfurase activity
MMZ59_12265	COG1959	2 iron, 2 sulfur cluster binding
MMZ59_12270	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MMZ59_12275	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MMZ59_12290	COG0124	histidyl-tRNA synthetase
MMZ59_12300	COG4991	sh3 domain protein
MMZ59_12300	COG0860	N-Acetylmuramoyl-L-alanine amidase
MMZ59_12300	COG3103	Sh3 type 3 domain protein
MMZ59_12305	COG1490	D-aminoacyl-tRNA deacylase activity
MMZ59_12310	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MMZ59_12315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MMZ59_12320	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MMZ59_12320	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MMZ59_12325	COG5416	Lipopolysaccharide assembly protein A domain
MMZ59_12330	COG0490	domain, Protein
MMZ59_12335	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MMZ59_12335	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MMZ59_12345	COG2244	polysaccharide biosynthetic process
MMZ59_12350	COG2323	membrane
MMZ59_12360	COG1862	Preprotein translocase
MMZ59_12365	COG0343	queuine tRNA-ribosyltransferase activity
MMZ59_12370	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MMZ59_12380	COG2255	four-way junction helicase activity
MMZ59_12385	COG0632	four-way junction helicase activity
MMZ59_12395	COG2112	serine threonine protein kinase
MMZ59_12410	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MMZ59_12430	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MMZ59_12435	COG0157	Belongs to the NadC ModD family
MMZ59_12440	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MMZ59_12445	COG1104	cysteine desulfurase activity
MMZ59_12450	COG1827	regulation of RNA biosynthetic process
MMZ59_12455	COG0077	Prephenate dehydratase
MMZ59_12460	COG4492	Belongs to the UPF0735 family
MMZ59_12465	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MMZ59_12470	COG3290	protein histidine kinase activity
MMZ59_12475	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MMZ59_12480	COG2868	ribosomal protein
MMZ59_12485	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MMZ59_12490	COG1994	Peptidase M50
MMZ59_12495	COG0739	heme binding
MMZ59_12500	COG2894	cell division
MMZ59_12505	COG0850	regulation of cytokinetic process
MMZ59_12510	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MMZ59_12520	COG1077	Cell shape determining protein MreB Mrl
MMZ59_12525	COG2003	Belongs to the UPF0758 family
MMZ59_12530	COG0424	maF-like protein
MMZ59_12540	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MMZ59_12545	COG0285	dihydrofolate synthase activity
MMZ59_12550	COG0525	valine-tRNA ligase activity
MMZ59_12560	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MMZ59_12565	COG1388	LysM domain
MMZ59_12570	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MMZ59_12575	COG0113	porphobilinogen synthase activity
MMZ59_12580	COG1587	Uroporphyrinogen-III synthase
MMZ59_12585	COG0181	hydroxymethylbilane synthase activity
MMZ59_12590	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MMZ59_12595	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MMZ59_12605	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MMZ59_12610	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MMZ59_12615	COG0470	DNA polymerase III
MMZ59_12615	COG1067	ATP-dependent peptidase activity
MMZ59_12620	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MMZ59_12625	COG0544	peptidyl-prolyl cis-trans isomerase activity
MMZ59_12630	COG0457	Tetratricopeptide repeat
MMZ59_12630	COG1477	protein flavinylation
MMZ59_12635	COG0066	3-isopropylmalate dehydratase activity
MMZ59_12640	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MMZ59_12645	COG0473	3-isopropylmalate dehydrogenase activity
MMZ59_12650	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MMZ59_12655	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MMZ59_12660	COG0440	acetolactate synthase activity
MMZ59_12665	COG0028	Belongs to the TPP enzyme family
MMZ59_12670	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MMZ59_12675	COG2706	6-phosphogluconolactonase activity
MMZ59_12680	COG3339	Conserved Protein
MMZ59_12685	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MMZ59_12690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MMZ59_12695	COG1696	Membrane protein involved in D-alanine export
MMZ59_12745	COG0582	viral genome integration into host DNA
MMZ59_12755	COG0622	Phosphoesterase
MMZ59_12760	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MMZ59_12765	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MMZ59_12770	COG5401	PFAM Sporulation and spore germination
MMZ59_12775	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MMZ59_12780	COG1846	Transcriptional regulator
MMZ59_12785	COG2197	response regulator
MMZ59_12790	COG2851	Citrate transporter
MMZ59_12795	COG0583	DNA-binding transcription factor activity
MMZ59_12800	COG2828	Protein conserved in bacteria
MMZ59_12810	COG0824	Thioesterase
MMZ59_12815	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MMZ59_12820	COG1053	succinate dehydrogenase
MMZ59_12825	COG2009	succinate dehydrogenase
MMZ59_12830	COG1719	4-vinyl reductase, 4VR
MMZ59_12835	COG0527	aspartate kinase activity
MMZ59_12840	COG0322	excinuclease ABC activity
MMZ59_12845	COG3118	belongs to the thioredoxin family
MMZ59_12850	COG3534	alpha-L-arabinofuranosidase
MMZ59_12855	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MMZ59_12860	COG2086	electron transfer activity
MMZ59_12865	COG1024	Enoyl-CoA hydratase
MMZ59_12870	COG1309	transcriptional regulator
MMZ59_12875	COG0318	PFAM AMP-dependent synthetase and ligase
MMZ59_12885	COG3766	membrane
MMZ59_12890	COG1193	negative regulation of DNA recombination
MMZ59_12895	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MMZ59_12895	COG1796	DNA polymerase
MMZ59_12900	COG1286	toxin biosynthetic process
MMZ59_12905	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MMZ59_12910	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MMZ59_12920	COG0072	phenylalanine-tRNA ligase activity
MMZ59_12920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MMZ59_12925	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MMZ59_12930	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MMZ59_12940	COG1966	Carbon starvation protein
MMZ59_12945	COG1363	Peptidase, m42
MMZ59_12955	COG3326	Membrane
MMZ59_12960	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MMZ59_12965	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MMZ59_12970	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MMZ59_12980	COG1011	Hydrolase
MMZ59_12990	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MMZ59_13000	COG0398	Pfam SNARE associated Golgi protein
MMZ59_13005	COG1484	DNA-dependent DNA replication
MMZ59_13010	COG3611	Membrane attachment protein
MMZ59_13015	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MMZ59_13025	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MMZ59_13030	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MMZ59_13035	COG0237	dephospho-CoA kinase activity
MMZ59_13040	COG1971	Probably functions as a manganese efflux pump
MMZ59_13045	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MMZ59_13050	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MMZ59_13050	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MMZ59_13055	COG5002	protein histidine kinase activity
MMZ59_13060	COG0745	RESPONSE REGULATOR receiver
MMZ59_13065	COG0039	L-malate dehydrogenase activity
MMZ59_13070	COG0538	isocitrate dehydrogenase activity
MMZ59_13075	COG0372	Belongs to the citrate synthase family
MMZ59_13080	COG2707	UPF0756 membrane protein
MMZ59_13085	COG0628	permease
MMZ59_13090	COG3030	protein affecting phage T7 exclusion by the F plasmid
MMZ59_13100	COG0205	6-phosphofructokinase activity
MMZ59_13105	COG0825	malonyl-CoA metabolic process
MMZ59_13110	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MMZ59_13115	COG0281	malic enzyme
MMZ59_13120	COG0587	DNA-directed DNA polymerase activity
MMZ59_13140	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MMZ59_13150	COG4109	DRTGG domain
MMZ59_13155	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MMZ59_13160	COG1028	Short-chain dehydrogenase reductase Sdr
MMZ59_13170	COG0165	Argininosuccinate lyase
MMZ59_13175	COG0137	argininosuccinate synthase activity
MMZ59_13180	COG0521	Mo-molybdopterin cofactor biosynthetic process
MMZ59_13185	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MMZ59_13190	COG0827	DNA restriction-modification system
MMZ59_13195	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MMZ59_13200	COG3874	Sporulation protein YtfJ
MMZ59_13210	COG1714	RDD family
MMZ59_13215	COG0616	signal peptide processing
MMZ59_13220	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MMZ59_13230	COG3239	Fatty acid desaturase
MMZ59_13235	COG4585	Histidine kinase
MMZ59_13240	COG2197	response regulator
MMZ59_13245	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MMZ59_13250	COG0745	RESPONSE REGULATOR receiver
MMZ59_13255	COG2205	protein histidine kinase activity
MMZ59_13260	COG0772	Belongs to the SEDS family
MMZ59_13265	COG1695	Transcriptional regulator
MMZ59_13270	COG1136	(ABC) transporter
MMZ59_13275	COG0577	efflux transmembrane transporter activity
MMZ59_13280	COG0402	S-adenosylhomocysteine deaminase activity
MMZ59_13285	COG2249	NAD(P)H dehydrogenase (quinone) activity
MMZ59_13305	COG1279	arginine transmembrane transporter activity
MMZ59_13310	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MMZ59_13320	COG0301	tRNA thio-modification
MMZ59_13325	COG1104	cysteine desulfurase activity
MMZ59_13330	COG1114	Component of the transport system for branched-chain amino acids
MMZ59_13335	COG1114	Component of the transport system for branched-chain amino acids
MMZ59_13340	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MMZ59_13345	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MMZ59_13350	COG1309	transcriptional regulator
MMZ59_13355	COG1956	GAF domain-containing protein
MMZ59_13360	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MMZ59_13370	COG1335	isochorismatase
MMZ59_13380	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MMZ59_13385	COG2329	Antibiotic biosynthesis monooxygenase
MMZ59_13390	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MMZ59_13395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MMZ59_13400	COG0454	-acetyltransferase
MMZ59_13405	COG0517	IMP dehydrogenase activity
MMZ59_13410	COG0123	including yeast histone deacetylase and acetoin utilization protein
MMZ59_13415	COG1609	Transcriptional regulator
MMZ59_13420	COG1605	Chorismate mutase
MMZ59_13420	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MMZ59_13425	COG3118	belongs to the thioredoxin family
MMZ59_13430	COG4980	gas vesicle protein
MMZ59_13435	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MMZ59_13440	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MMZ59_13445	COG1674	ftsk spoiiie
MMZ59_13450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MMZ59_13455	COG4848	Belongs to the UPF0354 family
MMZ59_13460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MMZ59_13475	COG1363	Peptidase, m42
MMZ59_13480	COG5584	Small secreted protein
MMZ59_13485	COG0281	malic enzyme
MMZ59_13490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MMZ59_13495	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MMZ59_13505	COG0510	thiamine kinase activity
MMZ59_13510	COG1597	lipid kinase activity
MMZ59_13520	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MMZ59_13525	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MMZ59_13530	COG3340	Belongs to the peptidase S51 family
MMZ59_13535	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MMZ59_13540	COG2252	PERMEase
MMZ59_13545	COG1349	DNA-binding transcription factor activity
MMZ59_13550	COG1187	pseudouridine synthase activity
MMZ59_13555	COG2244	polysaccharide biosynthetic process
MMZ59_13560	COG2081	HI0933 family
MMZ59_13570	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MMZ59_13575	COG3196	Protein conserved in bacteria
MMZ59_13585	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MMZ59_13590	COG5578	integral membrane protein
MMZ59_13595	COG0673	inositol 2-dehydrogenase activity
MMZ59_13600	COG1653	transport
MMZ59_13605	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
MMZ59_13610	COG4209	transmembrane transport
MMZ59_13615	COG2207	Transcriptional regulator
MMZ59_13620	COG1733	regulation of RNA biosynthetic process
MMZ59_13625	COG2814	Major facilitator Superfamily
MMZ59_13630	COG0656	L-ascorbic acid biosynthetic process
MMZ59_13635	COG1653	transport
MMZ59_13640	COG0395	ABC-type sugar transport system, permease component
MMZ59_13645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MMZ59_13650	COG1073	alpha beta
MMZ59_13655	COG0495	leucyl-tRNA aminoacylation
MMZ59_13665	COG2202	Pas domain
MMZ59_13665	COG1366	Belongs to the anti-sigma-factor antagonist family
MMZ59_13670	COG2433	Pfam Transposase IS66
MMZ59_13675	COG0577	efflux transmembrane transporter activity
MMZ59_13680	COG1136	(ABC) transporter
MMZ59_13690	COG1131	(ABC) transporter
MMZ59_13695	COG1725	Transcriptional regulator
MMZ59_13715	COG1242	4 iron, 4 sulfur cluster binding
MMZ59_13720	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MMZ59_13725	COG4326	sporulation control protein
MMZ59_13735	COG2267	carboxylic ester hydrolase activity
MMZ59_13740	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MMZ59_13745	COG0367	asparagine synthase
MMZ59_13750	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MMZ59_13755	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MMZ59_13765	COG1506	peptidase
MMZ59_13770	COG1233	COG1233 Phytoene dehydrogenase and related
MMZ59_13790	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MMZ59_13795	COG1116	anion transmembrane transporter activity
MMZ59_13800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MMZ59_13805	COG0494	nUDIX hydrolase
MMZ59_13810	COG2310	stress, protein
MMZ59_13825	COG4824	toxin secretion phage lysis holin
MMZ59_13835	COG0783	Belongs to the Dps family
MMZ59_13850	COG1854	S-ribosylhomocysteine lyase activity
MMZ59_13855	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MMZ59_13860	COG0288	reversible hydration of carbon dioxide
MMZ59_13865	COG0803	Belongs to the bacterial solute-binding protein 9 family
MMZ59_13865	COG3443	Belongs to the bacterial solute-binding protein 9 family
MMZ59_13875	COG1271	oxidase subunit
MMZ59_13880	COG1294	oxidase, subunit
MMZ59_13895	COG4948	Mandelate Racemase Muconate Lactonizing
MMZ59_13900	COG0318	PFAM AMP-dependent synthetase and ligase
MMZ59_13905	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MMZ59_13910	COG0596	Alpha beta hydrolase
MMZ59_13915	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MMZ59_13920	COG1169	isochorismate synthase
MMZ59_13925	COG1575	Belongs to the MenA family. Type 1 subfamily
MMZ59_13930	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MMZ59_14060	COG3859	Proton-coupled thiamine transporter YuaJ
MMZ59_14065	COG1247	-acetyltransferase
MMZ59_14070	COG3339	Conserved Protein
MMZ59_14075	COG0772	Belongs to the SEDS family
MMZ59_14080	COG0772	Belongs to the SEDS family
MMZ59_14085	COG2268	Band 7 protein
MMZ59_14090	COG1585	Membrane protein implicated in regulation of membrane protease activity
MMZ59_14095	COG2318	DinB family
MMZ59_14100	COG1454	alcohol dehydrogenase
MMZ59_14105	COG1012	belongs to the aldehyde dehydrogenase family
MMZ59_14110	COG1510	regulation of RNA biosynthetic process
MMZ59_14125	COG5632	N-Acetylmuramoyl-L-alanine amidase
MMZ59_14125	COG3409	Peptidoglycan-binding domain 1 protein
MMZ59_14180	COG3778	Protein conserved in bacteria
MMZ59_14185	COG3299	homolog of phage Mu protein gp47
MMZ59_14190	COG3628	GPW Gp25 family protein
MMZ59_14200	COG4193	domain, Protein
MMZ59_14205	COG1652	LysM domain
MMZ59_14210	COG5280	Phage tail tape measure protein TP901
MMZ59_14210	COG3953	SLT domain
MMZ59_14265	COG4653	Phage capsid family
MMZ59_14270	COG0338	D12 class N6 adenine-specific DNA methyltransferase
MMZ59_14275	COG5518	Phage portal protein
MMZ59_14280	COG1783	phage Terminase large subunit
MMZ59_14285	COG5484	DNA packaging
MMZ59_14290	COG1595	DNA-templated transcription, initiation
MMZ59_14300	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
MMZ59_14320	COG1396	sequence-specific DNA binding
MMZ59_14330	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MMZ59_14345	COG0628	permease
MMZ59_14355	COG0673	inositol 2-dehydrogenase activity
MMZ59_14360	COG0693	protein deglycase activity
MMZ59_14365	COG0840	transmembrane signaling receptor activity
MMZ59_14370	COG0840	transmembrane signaling receptor activity
MMZ59_14375	COG0840	transmembrane signaling receptor activity
MMZ59_14380	COG0840	transmembrane signaling receptor activity
MMZ59_14395	COG2070	2-Nitropropane dioxygenase
MMZ59_14400	COG0432	Pfam Uncharacterised protein family UPF0047
MMZ59_14405	COG1253	flavin adenine dinucleotide binding
MMZ59_14410	COG2738	Putative neutral zinc metallopeptidase
MMZ59_14420	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MMZ59_14435	COG0166	Belongs to the GPI family
MMZ59_14440	COG1979	alcohol dehydrogenase
MMZ59_14445	COG1979	alcohol dehydrogenase
MMZ59_14450	COG2155	Conserved Protein
MMZ59_14455	COG1098	S1 RNA binding domain
MMZ59_14460	COG0436	Aminotransferase
MMZ59_14465	COG1522	sequence-specific DNA binding
MMZ59_14470	COG2267	carboxylic ester hydrolase activity
MMZ59_14480	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MMZ59_14485	COG2205	protein histidine kinase activity
MMZ59_14500	COG5018	Exonuclease
MMZ59_14505	COG2814	Major facilitator Superfamily
MMZ59_14510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MMZ59_14515	COG3011	Protein conserved in bacteria
MMZ59_14525	COG3290	protein histidine kinase activity
MMZ59_14530	COG4565	transcriptional regulatory protein
MMZ59_14535	COG1744	ABC transporter substrate-binding protein PnrA-like
MMZ59_14540	COG3845	ABC transporter
MMZ59_14545	COG4603	Belongs to the binding-protein-dependent transport system permease family
MMZ59_14550	COG1079	Belongs to the binding-protein-dependent transport system permease family
MMZ59_14555	COG3493	citrate carrier protein
MMZ59_14565	COG2111	Na H antiporter
MMZ59_14565	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MMZ59_14570	COG2111	Na H antiporter
MMZ59_14575	COG1006	Multisubunit Na H antiporter MnhC subunit
MMZ59_14580	COG0651	ATP synthesis coupled electron transport
MMZ59_14585	COG1863	multisubunit Na H antiporter MnhE subunit
MMZ59_14590	COG2212	antiporter activity
MMZ59_14595	COG1320	monovalent cation:proton antiporter activity
MMZ59_14600	COG2050	protein possibly involved in aromatic compounds catabolism
MMZ59_14605	COG2197	response regulator
MMZ59_14610	COG4585	Histidine kinase
MMZ59_14620	COG0142	geranyltranstransferase activity
MMZ59_14635	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
MMZ59_14640	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MMZ59_14645	COG1335	isochorismatase
MMZ59_14650	COG5506	Protein of unknown function (DUF1694)
MMZ59_14670	COG0628	permease
MMZ59_14685	COG1418	mRNA catabolic process
MMZ59_14690	COG1028	Short-chain dehydrogenase reductase Sdr
MMZ59_14700	COG1511	domain protein
MMZ59_14705	COG0433	COG0433 Predicted ATPase
MMZ59_14705	COG1674	ftsk spoiiie
MMZ59_14710	COG4499	WXG100 protein secretion system (Wss), protein YukC
MMZ59_14715	COG5417	Belongs to the EsaB family
MMZ59_14720	COG4842	Belongs to the WXG100 family
MMZ59_14725	COG2508	Transcriptional regulator
MMZ59_14725	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MMZ59_14730	COG0686	Belongs to the AlaDH PNT family
MMZ59_14735	COG1268	BioY protein
MMZ59_14740	COG2056	Na+-H+ antiporter family
MMZ59_14745	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MMZ59_14750	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
MMZ59_14755	COG3584	3D domain protein
MMZ59_14770	COG1252	NADH dehydrogenase
MMZ59_14775	COG0492	ferredoxin-NADP+ reductase activity
MMZ59_14790	COG0789	Transcriptional regulator
MMZ59_14795	COG5504	Zn-dependent protease
MMZ59_14800	COG0316	Belongs to the HesB IscA family
MMZ59_14805	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MMZ59_14810	COG4844	belongs to the
MMZ59_14815	COG1252	NADH dehydrogenase
MMZ59_14825	COG4837	Protein of unknown function (DUF1462)
MMZ59_14835	COG0823	Involved in the tonB-independent uptake of proteins
MMZ59_14835	COG4946	Tricorn protease homolog
MMZ59_14835	COG1506	peptidase
MMZ59_14840	COG0083	homoserine kinase activity
MMZ59_14845	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MMZ59_14850	COG0460	homoserine dehydrogenase
MMZ59_14855	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MMZ59_14860	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MMZ59_14865	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MMZ59_14870	COG0647	UMP catabolic process
MMZ59_14875	COG2445	Protein of unknown function DUF86
MMZ59_14880	COG4470	Protein conserved in bacteria
MMZ59_14890	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MMZ59_14895	COG0739	heme binding
MMZ59_14915	COG3377	Domain of unknown function (DUF1805)
MMZ59_14920	COG0737	Belongs to the 5'-nucleotidase family
MMZ59_14925	COG1801	Protein of unknown function DUF72
MMZ59_14930	COG2508	Transcriptional regulator
MMZ59_14935	COG2140	Oxalate decarboxylase
MMZ59_14940	COG2814	Major facilitator Superfamily
MMZ59_14945	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MMZ59_14950	COG2356	endonuclease I
MMZ59_14965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MMZ59_14970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MMZ59_14975	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MMZ59_14995	COG0642	Histidine kinase
MMZ59_14995	COG5002	protein histidine kinase activity
MMZ59_15000	COG0745	RESPONSE REGULATOR receiver
MMZ59_15005	COG2311	Membrane
MMZ59_15015	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MMZ59_15020	COG1090	epimerase
MMZ59_15025	COG1309	transcriptional regulator
MMZ59_15035	COG0719	Fe-S assembly protein
MMZ59_15040	COG0822	iron-sulfur transferase activity
MMZ59_15045	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MMZ59_15050	COG0719	Fe-S assembly protein
MMZ59_15055	COG0396	ATPase activity
MMZ59_15065	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MMZ59_15070	COG1464	Belongs to the NlpA lipoprotein family
MMZ59_15075	COG2011	ABC-type metal ion transport system permease component
MMZ59_15080	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MMZ59_15090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MMZ59_15095	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MMZ59_15105	COG0509	glycine decarboxylation via glycine cleavage system
MMZ59_15110	COG1393	Belongs to the ArsC family
MMZ59_15115	COG1960	acyl-CoA dehydrogenase activity
MMZ59_15120	COG0183	Belongs to the thiolase family
MMZ59_15125	COG1024	Enoyl-CoA hydratase
MMZ59_15125	COG1250	3-hydroxyacyl-CoA dehydrogenase
MMZ59_15140	COG5577	PFAM Coat F domain
MMZ59_15150	COG1120	ATPase activity
MMZ59_15160	COG1028	Short-chain dehydrogenase reductase Sdr
MMZ59_15165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MMZ59_15170	COG0745	RESPONSE REGULATOR receiver
MMZ59_15175	COG2205	protein histidine kinase activity
MMZ59_15175	COG2770	Histidine kinase
MMZ59_15185	COG1309	transcriptional regulator
MMZ59_15190	COG0114	fumarate hydratase activity
MMZ59_15200	COG0697	spore germination
MMZ59_15205	COG0814	amino acid
MMZ59_15220	COG2197	response regulator
MMZ59_15225	COG4585	Histidine kinase
MMZ59_15230	COG4758	membrane
MMZ59_15240	COG1842	Phage shock protein A
MMZ59_15245	COG4758	membrane
MMZ59_15250	COG2096	Adenosyltransferase
MMZ59_15255	COG1028	Short-chain dehydrogenase reductase Sdr
MMZ59_15265	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MMZ59_15275	COG3604	Transcriptional regulator
MMZ59_15290	COG1454	alcohol dehydrogenase
MMZ59_15295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MMZ59_15300	COG1120	ATPase activity
MMZ59_15305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MMZ59_15310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MMZ59_15320	COG2721	sulfolactate sulfo-lyase activity
MMZ59_15325	COG0246	Mannitol dehydrogenase
MMZ59_15330	COG1609	Transcriptional regulator
MMZ59_15335	COG1904	glucuronate isomerase
MMZ59_15340	COG2205	protein histidine kinase activity
MMZ59_15345	COG0745	RESPONSE REGULATOR receiver
MMZ59_15350	COG1120	ATPase activity
MMZ59_15355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MMZ59_15360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MMZ59_15365	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MMZ59_15370	COG0531	amino acid
MMZ59_15385	COG1988	membrane-bound metal-dependent
MMZ59_15390	COG1368	sulfuric ester hydrolase activity
MMZ59_15395	COG0725	ABC transporter, periplasmic molybdate-binding protein
MMZ59_15400	COG4149	molybdate abc transporter
MMZ59_15405	COG0656	L-ascorbic acid biosynthetic process
MMZ59_15410	COG1940	carbohydrate kinase activity
MMZ59_15415	COG0025	NhaP-type Na H and K H
MMZ59_15420	COG2860	membrane
MMZ59_15425	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MMZ59_15430	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MMZ59_15435	COG2217	Heavy metal translocating P-type atpase
MMZ59_15440	COG1121	(ABC) transporter
MMZ59_15445	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MMZ59_15450	COG0803	Belongs to the bacterial solute-binding protein 9 family
MMZ59_15460	COG3226	Transcriptional regulator
MMZ59_15465	COG0784	Response regulator, receiver
MMZ59_15470	COG4191	Histidine kinase
MMZ59_15475	COG1027	Aspartate ammonia-lyase
MMZ59_15490	COG2217	Heavy metal translocating P-type atpase
MMZ59_15495	COG2608	mercury ion transmembrane transporter activity
MMZ59_15500	COG1937	Protein conserved in bacteria
MMZ59_15520	COG0463	Glycosyl transferase, family 2
MMZ59_15520	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MMZ59_15530	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MMZ59_15535	COG0557	exoribonuclease II activity
MMZ59_15540	COG1647	Serine aminopeptidase, S33
MMZ59_15545	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MMZ59_15550	COG2002	toxin-antitoxin pair type II binding
MMZ59_15555	COG1476	TRANSCRIPTIONal
MMZ59_15560	COG1396	sequence-specific DNA binding
MMZ59_15565	COG1396	sequence-specific DNA binding
MMZ59_15570	COG1733	regulation of RNA biosynthetic process
MMZ59_15575	COG1174	glycine betaine transport
MMZ59_15580	COG1732	Glycine betaine
MMZ59_15585	COG1174	glycine betaine transport
MMZ59_15590	COG0517	IMP dehydrogenase activity
MMZ59_15590	COG1125	glycine betaine transport
MMZ59_15595	COG1510	regulation of RNA biosynthetic process
MMZ59_15600	COG2095	MarC family integral membrane protein
MMZ59_15610	COG0456	acetyltransferase
MMZ59_15630	COG1131	(ABC) transporter
MMZ59_15640	COG0148	phosphopyruvate hydratase activity
MMZ59_15645	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MMZ59_15650	COG0149	triose-phosphate isomerase activity
MMZ59_15655	COG0126	phosphoglycerate kinase activity
MMZ59_15660	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MMZ59_15665	COG2390	Transcriptional regulator
MMZ59_15670	COG0833	amino acid
MMZ59_15675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MMZ59_15680	COG3829	transcription factor binding
MMZ59_15685	COG2186	Transcriptional regulator
MMZ59_15690	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MMZ59_15700	COG0534	Mate efflux family protein
MMZ59_15705	COG4608	Belongs to the ABC transporter superfamily
MMZ59_15710	COG0444	Belongs to the ABC transporter superfamily
MMZ59_15715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MMZ59_15720	COG0601	transmembrane transport
MMZ59_15725	COG0747	negative chemotaxis
MMZ59_15730	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MMZ59_15735	COG0110	maltose O-acetyltransferase activity
MMZ59_15740	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MMZ59_15745	COG2244	polysaccharide biosynthetic process
MMZ59_15750	COG5039	Polysaccharide pyruvyl transferase
MMZ59_15755	COG1216	Glycosyl transferase, family 2
MMZ59_15765	COG0438	transferase activity, transferring glycosyl groups
MMZ59_15770	COG1215	transferase activity, transferring glycosyl groups
MMZ59_15775	COG0438	transferase activity, transferring glycosyl groups
MMZ59_15780	COG1086	Polysaccharide biosynthesis protein
MMZ59_15785	COG0489	protein tyrosine kinase activity
MMZ59_15790	COG3944	biosynthesis protein
MMZ59_15795	COG1396	sequence-specific DNA binding
MMZ59_15805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MMZ59_15810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MMZ59_15815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MMZ59_15820	COG0726	polysaccharide deacetylase
MMZ59_15825	COG0488	(ABC) transporter
MMZ59_15830	COG4608	Belongs to the ABC transporter superfamily
MMZ59_15845	COG0601	transmembrane transport
MMZ59_15850	COG0747	negative chemotaxis
MMZ59_15855	COG1819	glycosyl
MMZ59_15870	COG0740	serine-type endopeptidase activity
MMZ59_15875	COG1611	Belongs to the LOG family
MMZ59_15880	COG1694	Mazg nucleotide pyrophosphohydrolase
MMZ59_15885	COG0659	secondary active sulfate transmembrane transporter activity
MMZ59_15890	COG0288	reversible hydration of carbon dioxide
MMZ59_15895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MMZ59_15910	COG2162	N-hydroxyarylamine O-acetyltransferase activity
MMZ59_15915	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MMZ59_15920	COG1481	regulation of sporulation
MMZ59_15925	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MMZ59_15930	COG1660	Displays ATPase and GTPase activities
MMZ59_15935	COG1051	belongs to the nudix hydrolase family
MMZ59_15940	COG0492	ferredoxin-NADP+ reductase activity
MMZ59_15945	COG0791	NLP P60 protein
MMZ59_15945	COG3883	PFAM NLP P60 protein
MMZ59_15950	COG0457	Tetratricopeptide repeat
MMZ59_15955	COG0140	phosphoribosyl-ATP diphosphatase activity
MMZ59_15955	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MMZ59_15960	COG0107	imidazoleglycerol-phosphate synthase activity
MMZ59_15965	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MMZ59_15970	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MMZ59_15975	COG0131	Imidazoleglycerol-phosphate dehydratase
MMZ59_15980	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MMZ59_15985	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MMZ59_15990	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MMZ59_15995	COG4990	cell redox homeostasis
MMZ59_16010	COG2910	NAD(P)H-binding
MMZ59_16015	COG1959	2 iron, 2 sulfur cluster binding
MMZ59_16020	COG0110	maltose O-acetyltransferase activity
MMZ59_16025	COG0546	phosphoglycolate phosphatase activity
MMZ59_16030	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
MMZ59_16040	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MMZ59_16045	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MMZ59_16050	COG0363	glucosamine-6-phosphate deaminase activity
MMZ59_16055	COG2188	Transcriptional regulator
MMZ59_16060	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MMZ59_16065	COG1950	PFAM Membrane protein of
MMZ59_16070	COG1983	PspC domain protein
MMZ59_16075	COG3595	metallopeptidase activity
MMZ59_16090	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MMZ59_16100	COG4897	Protein conserved in bacteria
MMZ59_16105	COG0574	Belongs to the PEP-utilizing enzyme family
MMZ59_16105	COG3848	Pyruvate phosphate dikinase
MMZ59_16110	COG1309	transcriptional regulator
MMZ59_16115	COG2814	Major facilitator Superfamily
MMZ59_16125	COG2814	Major facilitator Superfamily
MMZ59_16135	COG0745	RESPONSE REGULATOR receiver
MMZ59_16140	COG5002	protein histidine kinase activity
MMZ59_16145	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MMZ59_16150	COG0463	Glycosyl transferase, family 2
MMZ59_16155	COG1113	amino acid transport
MMZ59_16160	COG0778	Nitroreductase
MMZ59_16165	COG1733	regulation of RNA biosynthetic process
MMZ59_16170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MMZ59_16180	COG0793	Belongs to the peptidase S41A family
MMZ59_16180	COG3409	Peptidoglycan-binding domain 1 protein
MMZ59_16185	COG0730	response to heat
MMZ59_16190	COG0791	NLP P60 protein
MMZ59_16190	COG3883	PFAM NLP P60 protein
MMZ59_16195	COG2177	Part of the ABC transporter FtsEX involved in
MMZ59_16200	COG2884	Cell division ATP-binding protein ftsE
MMZ59_16205	COG2010	Cytochrome c
MMZ59_16210	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MMZ59_16230	COG0653	protein targeting
MMZ59_16235	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MMZ59_16240	COG0840	transmembrane signaling receptor activity
MMZ59_16255	COG1516	flagellar protein fliS
MMZ59_16260	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MMZ59_16265	COG1334	flagellar protein FlaG
MMZ59_16270	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MMZ59_16275	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MMZ59_16285	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MMZ59_16290	COG1256	bacterial-type flagellum assembly
MMZ59_16290	COG4786	Flagellar basal body rod
MMZ59_16295	COG3418	PFAM FlgN family protein
MMZ59_16310	COG1040	competence protein
MMZ59_16320	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MMZ59_16325	COG1307	EDD domain protein, DegV family
MMZ59_16330	COG2197	response regulator
MMZ59_16335	COG4585	Histidine kinase
MMZ59_16340	COG1739	Uncharacterized protein family UPF0029
MMZ59_16345	COG1316	TRANSCRIPTIONal
MMZ59_16350	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MMZ59_16355	COG0438	transferase activity, transferring glycosyl groups
MMZ59_16360	COG1215	transferase activity, transferring glycosyl groups
MMZ59_16365	COG3206	protein involved in exopolysaccharide biosynthesis
MMZ59_16370	COG3307	-O-antigen
MMZ59_16375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MMZ59_16380	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MMZ59_16385	COG0297	glycogen (starch) synthase activity
MMZ59_16385	COG0438	transferase activity, transferring glycosyl groups
MMZ59_16390	COG2244	polysaccharide biosynthetic process
MMZ59_16405	COG0860	N-Acetylmuramoyl-L-alanine amidase
MMZ59_16405	COG2247	cell wall binding repeat
MMZ59_16410	COG0860	N-Acetylmuramoyl-L-alanine amidase
MMZ59_16410	COG2247	cell wall binding repeat
MMZ59_16415	COG2247	cell wall binding repeat
MMZ59_16415	COG2385	sporulation resulting in formation of a cellular spore
MMZ59_16425	COG1316	TRANSCRIPTIONal
MMZ59_16430	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MMZ59_16430	COG1215	transferase activity, transferring glycosyl groups
MMZ59_16435	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MMZ59_16440	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MMZ59_16445	COG1134	teichoic acid transport
MMZ59_16450	COG1682	transport, permease protein
MMZ59_16455	COG0463	Glycosyl transferase, family 2
MMZ59_16470	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MMZ59_16475	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
MMZ59_16480	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MMZ59_16485	COG4193	domain, Protein
MMZ59_16490	COG1482	cell wall glycoprotein biosynthetic process
MMZ59_16500	COG1175	transmembrane transport
MMZ59_16505	COG1653	transport
MMZ59_16510	COG2197	response regulator
MMZ59_16515	COG2972	Histidine kinase
MMZ59_16525	COG0454	-acetyltransferase
MMZ59_16530	COG0800	Aldolase
MMZ59_16535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MMZ59_16540	COG1609	Transcriptional regulator
MMZ59_16545	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MMZ59_16550	COG1028	Short-chain dehydrogenase reductase Sdr
MMZ59_16555	COG0697	spore germination
MMZ59_16560	COG0814	amino acid
MMZ59_16575	COG2814	Major facilitator Superfamily
MMZ59_16580	COG1316	TRANSCRIPTIONal
MMZ59_16585	COG0561	phosphatase activity
MMZ59_16590	COG0791	NLP P60 protein
MMZ59_16600	COG2843	Capsule synthesis protein
MMZ59_16610	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MMZ59_16615	COG0697	spore germination
MMZ59_16630	COG1609	Transcriptional regulator
MMZ59_16635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MMZ59_16640	COG1869	D-ribose catabolic process
MMZ59_16645	COG1129	ABC transporter
MMZ59_16650	COG1172	Belongs to the binding-protein-dependent transport system permease family
MMZ59_16655	COG1879	ABC-type sugar transport system periplasmic component
MMZ59_16660	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MMZ59_16665	COG0583	DNA-binding transcription factor activity
MMZ59_16670	COG0028	Belongs to the TPP enzyme family
MMZ59_16675	COG3527	Alpha-acetolactate decarboxylase
MMZ59_16680	COG1522	sequence-specific DNA binding
MMZ59_16685	COG2059	Chromate
MMZ59_16690	COG2059	Chromate
MMZ59_16695	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MMZ59_16705	COG4715	Zinc finger, swim domain protein
MMZ59_16710	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MMZ59_16715	COG2202	Pas domain
MMZ59_16715	COG1366	Belongs to the anti-sigma-factor antagonist family
MMZ59_16720	COG0561	phosphatase activity
MMZ59_16735	COG1970	mechanosensitive ion channel activity
MMZ59_16740	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MMZ59_16745	COG0457	Tetratricopeptide repeat
MMZ59_16750	COG4786	Flagellar basal body rod
MMZ59_16755	COG4786	Flagellar basal body rod
MMZ59_16760	COG1077	Cell shape determining protein MreB Mrl
MMZ59_16765	COG1609	Transcriptional regulator
MMZ59_16770	COG1846	Transcriptional regulator
MMZ59_16775	COG2814	Major facilitator Superfamily
MMZ59_16780	COG0671	phosphoesterase, PA-phosphatase related
MMZ59_16785	COG0477	Major facilitator Superfamily
MMZ59_16790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MMZ59_16795	COG0765	amino acid transport
MMZ59_16800	COG1126	abc transporter atp-binding protein
MMZ59_16805	COG0004	ammonium transporteR
MMZ59_16810	COG0347	Belongs to the P(II) protein family
MMZ59_16815	COG0739	heme binding
MMZ59_16820	COG1247	-acetyltransferase
MMZ59_16855	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MMZ59_16860	COG0523	cobalamin synthesis protein
MMZ59_16865	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MMZ59_16870	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MMZ59_16875	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MMZ59_16880	COG2223	nitrite transmembrane transporter activity
MMZ59_16890	COG2304	oxidoreductase activity
MMZ59_16895	COG2304	oxidoreductase activity
MMZ59_16900	COG2385	sporulation resulting in formation of a cellular spore
MMZ59_16905	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MMZ59_16915	COG4836	Membrane
MMZ59_16925	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MMZ59_16930	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MMZ59_16935	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MMZ59_16940	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MMZ59_16945	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MMZ59_16950	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MMZ59_16955	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MMZ59_16960	COG0356	it plays a direct role in the translocation of protons across the membrane
MMZ59_16970	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MMZ59_16975	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MMZ59_16980	COG4475	Protein of unknown function (DUF436)
MMZ59_16985	COG0698	ribose 5-phosphate isomerase
MMZ59_16990	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MMZ59_16995	COG1971	Probably functions as a manganese efflux pump
MMZ59_17000	COG0009	L-threonylcarbamoyladenylate synthase
MMZ59_17005	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MMZ59_17020	COG2890	protein-(glutamine-N5) methyltransferase activity
MMZ59_17025	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MMZ59_17030	COG0789	Transcriptional regulator
MMZ59_17035	COG0679	Auxin Efflux Carrier
MMZ59_17040	COG0281	malic enzyme
MMZ59_17045	COG1435	thymidine kinase activity
MMZ59_17050	COG0254	rRNA binding
MMZ59_17055	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MMZ59_17060	COG1494	fructose-1,6-bisphosphatase
MMZ59_17065	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MMZ59_17070	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MMZ59_17075	COG0191	fructose-bisphosphate aldolase activity
MMZ59_17080	COG2204	response regulator
MMZ59_17085	COG4821	SIS domain
MMZ59_17090	COG0504	CTP synthase activity
MMZ59_17095	COG3343	RNA polymerase activity
MMZ59_17110	COG1960	acyl-CoA dehydrogenase activity
MMZ59_17115	COG1960	acyl-CoA dehydrogenase activity
MMZ59_17120	COG1250	3-hydroxyacyl-CoA dehydrogenase
MMZ59_17125	COG0183	Belongs to the thiolase family
MMZ59_17130	COG0247	lactate metabolic process
MMZ59_17130	COG2181	nitrate reductase activity
MMZ59_17135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MMZ59_17140	COG4294	response to UV
MMZ59_17150	COG1619	proteins homologs of microcin C7 resistance protein MccF
MMZ59_17160	COG1132	(ABC) transporter
MMZ59_17165	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MMZ59_17170	COG1619	proteins homologs of microcin C7 resistance protein MccF
MMZ59_17175	COG0018	arginyl-trna synthetase
MMZ59_17180	COG4506	Protein conserved in bacteria
MMZ59_17190	COG0010	Belongs to the arginase family
MMZ59_17195	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MMZ59_17200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MMZ59_17210	COG1994	Peptidase M50
MMZ59_17215	COG1942	4-Oxalocrotonate Tautomerase
MMZ59_17225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MMZ59_17230	COG0583	DNA-binding transcription factor activity
MMZ59_17235	COG0431	NADPH-dependent FMN reductase
MMZ59_17240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MMZ59_17245	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MMZ59_17250	COG0454	-acetyltransferase
MMZ59_17255	COG0765	amino acid transport
MMZ59_17265	COG0765	amino acid transport
MMZ59_17270	COG1126	abc transporter atp-binding protein
MMZ59_17275	COG3465	dGTPase activity
MMZ59_17280	COG1078	dGTPase activity
MMZ59_17285	COG4844	belongs to the
MMZ59_17335	COG5444	nuclease activity
MMZ59_17365	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MMZ59_17375	COG0280	phosphate acetyltransferase
MMZ59_17385	COG2814	Major facilitator Superfamily
MMZ59_17390	COG1522	sequence-specific DNA binding
MMZ59_17395	COG2814	Major facilitator Superfamily
MMZ59_17400	COG0077	Prephenate dehydratase
MMZ59_17405	COG1917	Cupin 2, conserved barrel domain protein
MMZ59_17410	COG1028	Short-chain dehydrogenase reductase Sdr
MMZ59_17415	COG0151	Belongs to the GarS family
MMZ59_17420	COG0436	Aminotransferase
MMZ59_17425	COG1028	Short-chain dehydrogenase reductase Sdr
MMZ59_17430	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
MMZ59_17435	COG1091	dTDP-4-dehydrorhamnose reductase activity
MMZ59_17440	COG1088	dTDP-glucose 4,6-dehydratase activity
MMZ59_17445	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MMZ59_17450	COG3980	spore coat polysaccharide biosynthesis protein
MMZ59_17455	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
MMZ59_17460	COG2089	acid synthase
MMZ59_17465	COG0456	acetyltransferase
MMZ59_17470	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MMZ59_17475	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MMZ59_17480	COG0463	Glycosyl transferase, family 2
MMZ59_17500	COG2363	Small membrane protein
MMZ59_17505	COG2233	PERMEase
MMZ59_17515	COG1012	belongs to the aldehyde dehydrogenase family
MMZ59_17520	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MMZ59_17525	COG1216	Glycosyl transferase, family 2
MMZ59_17535	COG0351	phosphomethylpyrimidine kinase
MMZ59_17550	COG1621	beta-fructofuranosidase activity
MMZ59_17555	COG1263	PTS System
MMZ59_17555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MMZ59_17560	COG3711	transcriptional antiterminator
MMZ59_17570	COG1404	Belongs to the peptidase S8 family
MMZ59_17580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MMZ59_17585	COG0778	Nitroreductase
MMZ59_17590	COG0772	Belongs to the SEDS family
MMZ59_17600	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MMZ59_17605	COG1845	cytochrome c oxidase, subunit III
MMZ59_17610	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MMZ59_17615	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MMZ59_17625	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
MMZ59_17630	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MMZ59_17635	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MMZ59_17650	COG2246	polysaccharide biosynthetic process
MMZ59_17670	COG3162	membrane
MMZ59_17675	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MMZ59_17685	COG0352	thiamine-phosphate diphosphorylase activity
MMZ59_17690	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MMZ59_17695	COG0583	DNA-binding transcription factor activity
MMZ59_17700	COG1380	Effector of murein hydrolase LrgA
MMZ59_17705	COG1346	cytolysis
MMZ59_17710	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MMZ59_17715	COG0346	lactoylglutathione lyase activity
MMZ59_17725	COG0765	amino acid transport
MMZ59_17730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MMZ59_17735	COG0457	Tetratricopeptide repeat
MMZ59_17745	COG2357	RelA SpoT domain protein
MMZ59_17750	COG1172	Belongs to the binding-protein-dependent transport system permease family
MMZ59_17755	COG1129	ABC transporter
MMZ59_17765	COG3420	alginic acid biosynthetic process
MMZ59_17770	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MMZ59_17780	COG1486	melibiose metabolic process
MMZ59_17785	COG1447	Phosphotransferase system cellobiose-specific component IIA
MMZ59_17790	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MMZ59_17795	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MMZ59_17800	COG3711	transcriptional antiterminator
MMZ59_17800	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MMZ59_17820	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MMZ59_17835	COG1595	DNA-templated transcription, initiation
MMZ59_17845	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MMZ59_17850	COG4988	ABC transporter
MMZ59_17855	COG1294	oxidase, subunit
MMZ59_17860	COG1271	oxidase subunit
MMZ59_17875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MMZ59_17880	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MMZ59_17885	COG4509	Sortase family
MMZ59_17910	COG5386	Cell surface protein
MMZ59_17915	COG5386	Cell surface protein
MMZ59_17920	COG1733	regulation of RNA biosynthetic process
MMZ59_17925	COG2514	catechol 2,3-dioxygenase activity
MMZ59_17930	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MMZ59_17930	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MMZ59_17935	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MMZ59_17935	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MMZ59_17945	COG0726	polysaccharide deacetylase
MMZ59_17950	COG1447	Phosphotransferase system cellobiose-specific component IIA
MMZ59_17955	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MMZ59_17960	COG2723	6-phospho-beta-galactosidase activity
MMZ59_17965	COG1312	Catalyzes the dehydration of D-mannonate
MMZ59_17975	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MMZ59_17980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MMZ59_17980	COG3711	transcriptional antiterminator
MMZ59_18005	COG1757	Na H antiporter
MMZ59_18010	COG1027	Aspartate ammonia-lyase
MMZ59_18015	COG0252	asparaginase activity
MMZ59_18020	COG1396	sequence-specific DNA binding
MMZ59_18045	COG4842	Belongs to the WXG100 family
MMZ59_18050	COG2195	Cleaves the N-terminal amino acid of tripeptides
MMZ59_18070	COG1737	Transcriptional regulator
MMZ59_18075	COG2084	Dehydrogenase
MMZ59_18085	COG2610	gluconate transmembrane transporter activity
MMZ59_18090	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MMZ59_18095	COG2850	peptidyl-arginine hydroxylation
MMZ59_18110	COG0454	-acetyltransferase
MMZ59_18120	COG2723	6-phospho-beta-galactosidase activity
MMZ59_18125	COG1263	PTS System
MMZ59_18125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MMZ59_18125	COG2190	(PTS) system
MMZ59_18130	COG3711	transcriptional antiterminator
MMZ59_18135	COG3878	Protein conserved in bacteria
MMZ59_18145	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MMZ59_18150	COG1122	ATPase activity
MMZ59_18155	COG4721	ABC-type cobalt transport system, permease component
MMZ59_18160	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MMZ59_18195	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
MMZ59_18200	COG0778	Nitroreductase
MMZ59_18205	COG1846	Transcriptional regulator
MMZ59_18210	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
MMZ59_18215	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MMZ59_18220	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MMZ59_18225	COG2390	Transcriptional regulator
MMZ59_18235	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MMZ59_18235	COG2755	lipolytic protein G-D-S-L family
MMZ59_18240	COG0477	Major facilitator Superfamily
MMZ59_18245	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MMZ59_18250	COG2226	methyltransferase
MMZ59_18260	COG0561	phosphatase activity
MMZ59_18265	COG0789	Transcriptional regulator
MMZ59_18270	COG0673	inositol 2-dehydrogenase activity
MMZ59_18275	COG0840	transmembrane signaling receptor activity
MMZ59_18280	COG1113	amino acid transport
MMZ59_18285	COG4335	DNA alkylation repair
MMZ59_18295	COG1070	Carbohydrate kinase
MMZ59_18300	COG1737	Transcriptional regulator
MMZ59_18340	COG0583	DNA-binding transcription factor activity
MMZ59_18345	COG1609	Transcriptional regulator
MMZ59_18350	COG2182	Extracellular solute-binding protein
MMZ59_18355	COG1175	transmembrane transport
MMZ59_18360	COG3833	ABC-type maltose transport systems, permease component
MMZ59_18370	COG1874	Beta-galactosidase
MMZ59_18375	COG2851	Citrate transporter
MMZ59_18385	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MMZ59_18390	COG1131	(ABC) transporter
MMZ59_18395	COG2824	Alkylphosphonate utilization operon protein PhnA
MMZ59_18400	COG1929	Belongs to the glycerate kinase type-1 family
MMZ59_18405	COG2610	gluconate transmembrane transporter activity
MMZ59_18410	COG3835	regulator
MMZ59_18415	COG1309	transcriptional regulator
MMZ59_18420	COG2814	Major facilitator Superfamily
MMZ59_18430	COG1136	(ABC) transporter
MMZ59_18435	COG0457	Tetratricopeptide repeat
MMZ59_18440	COG3711	transcriptional antiterminator
MMZ59_18445	COG2723	6-phospho-beta-galactosidase activity
MMZ59_18450	COG1263	PTS System
MMZ59_18450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MMZ59_18450	COG2190	(PTS) system
MMZ59_18475	COG0494	nUDIX hydrolase
MMZ59_18490	COG1113	amino acid transport
MMZ59_18495	COG1609	Transcriptional regulator
MMZ59_18500	COG2814	Major facilitator Superfamily
MMZ59_18505	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MMZ59_18510	COG2814	Major facilitator Superfamily
MMZ59_18515	COG2723	6-phospho-beta-galactosidase activity
MMZ59_18525	COG2190	(PTS) system
MMZ59_18525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MMZ59_18525	COG1263	PTS System
MMZ59_18540	COG5444	nuclease activity
MMZ59_18560	COG2723	6-phospho-beta-galactosidase activity
MMZ59_18570	COG2188	Transcriptional regulator
MMZ59_18585	COG0384	phenazine biosynthesis protein PhzF
MMZ59_18590	COG0583	DNA-binding transcription factor activity
MMZ59_18610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MMZ59_18625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MMZ59_18640	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MMZ59_18650	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MMZ59_18660	COG4720	Psort location CytoplasmicMembrane, score
MMZ59_18680	COG0456	acetyltransferase
MMZ59_18685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MMZ59_18690	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MMZ59_18695	COG4853	Protein conserved in bacteria
MMZ59_18700	COG4863	YycH protein
MMZ59_18705	COG5002	protein histidine kinase activity
MMZ59_18710	COG0745	RESPONSE REGULATOR receiver
MMZ59_18735	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MMZ59_18750	COG2311	Membrane
MMZ59_18755	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MMZ59_18760	COG1309	transcriptional regulator
MMZ59_18765	COG2124	cytochrome p450
MMZ59_18770	COG0346	lactoylglutathione lyase activity
MMZ59_18775	COG0305	Participates in initiation and elongation during chromosome replication
MMZ59_18790	COG2819	hydrolase of the alpha beta superfamily
MMZ59_18795	COG1028	Short-chain dehydrogenase reductase Sdr
MMZ59_18800	COG1169	isochorismate synthase
MMZ59_18805	COG1021	2,3-dihydroxybenzoate-AMP ligase
MMZ59_18810	COG1535	isochorismatase
MMZ59_18810	COG3433	isochorismatase activity
MMZ59_18815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MMZ59_18820	COG3251	PFAM MbtH domain protein
MMZ59_18825	COG2207	Transcriptional regulator
MMZ59_18825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MMZ59_18830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MMZ59_18835	COG2819	hydrolase of the alpha beta superfamily
MMZ59_18840	COG3093	addiction module antidote protein HigA
MMZ59_18845	COG2807	transmembrane transport
MMZ59_18850	COG0359	binds to the 23S rRNA
MMZ59_18855	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
MMZ59_18860	COG4241	membrane
MMZ59_18865	COG1227	inorganic diphosphatase activity
MMZ59_18875	COG1595	DNA-templated transcription, initiation
MMZ59_18885	COG0753	catalase activity
MMZ59_18890	COG0655	NAD(P)H dehydrogenase (quinone) activity
MMZ59_18895	COG0400	carboxylic ester hydrolase activity
MMZ59_18900	COG0346	lactoylglutathione lyase activity
MMZ59_18905	COG1174	glycine betaine transport
MMZ59_18910	COG1125	glycine betaine transport
MMZ59_18910	COG0517	IMP dehydrogenase activity
MMZ59_18915	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MMZ59_18920	COG0629	single-stranded DNA binding
MMZ59_18925	COG0360	Binds together with S18 to 16S ribosomal RNA
MMZ59_18930	COG0012	GTP binding
MMZ59_18935	COG4481	Protein conserved in bacteria
MMZ59_18950	COG3949	Membrane
MMZ59_18960	COG1475	DNA binding
MMZ59_18965	COG1192	Involved in chromosome partitioning
MMZ59_18975	COG1475	DNA binding
MMZ59_18980	COG0357	Ribosomal RNA small subunit methyltransferase G
MMZ59_18985	COG0445	tRNA wobble uridine modification
MMZ59_18990	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MMZ59_18995	COG1847	R3H domain protein
MMZ59_19000	COG0706	membrane insertase activity
MMZ59_19005	COG0594	ribonuclease P activity
MMZ59_19010	COG0230	Belongs to the bacterial ribosomal protein bL34 family