locus-tag	class	description
NC3_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NC3_00020	COG0592	DNA-directed DNA polymerase activity
NC3_00030	COG2501	S4 domain
NC3_00040	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NC3_00060	COG0187	DNA topoisomerase II activity
NC3_00070	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NC3_00090	COG0516	GMP reductase activity
NC3_00090	COG0517	IMP dehydrogenase activity
NC3_00100	COG1686	Belongs to the peptidase S11 family
NC3_00110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NC3_00120	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NC3_00130	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NC3_00140	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NC3_00150	COG0840	transmembrane signaling receptor activity
NC3_00160	COG1428	Deoxynucleoside kinase
NC3_00170	COG1428	Deoxynucleoside kinase
NC3_00180	COG1388	LysM domain
NC3_00180	COG3858	chitin binding
NC3_00190	COG1335	isochorismatase
NC3_00200	COG0590	tRNA wobble adenosine to inosine editing
NC3_00210	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NC3_00220	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NC3_00230	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NC3_00270	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
NC3_00280	COG3853	Toxic anion resistance protein (TelA)
NC3_00290	COG1982	Orn Lys Arg decarboxylase major
NC3_00300	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NC3_00310	COG3870	Protein conserved in bacteria
NC3_00320	COG1728	Protein conserved in bacteria
NC3_00330	COG0470	DNA polymerase III
NC3_00340	COG1774	PSP1 C-terminal conserved region
NC3_00350	COG4467	Involved in initiation control of chromosome replication
NC3_00360	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NC3_00370	COG2827	Endonuclease containing a URI domain
NC3_00380	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NC3_00390	COG2002	toxin-antitoxin pair type II binding
NC3_00400	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NC3_00400	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NC3_00410	COG0084	hydrolase, TatD family'
NC3_00420	COG3583	domain protein
NC3_00420	COG3584	3D domain protein
NC3_00430	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NC3_00440	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NC3_00460	COG4466	Protein conserved in bacteria
NC3_00480	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NC3_00490	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NC3_00500	COG0251	oxidation-reduction process
NC3_00510	COG2088	sporulation resulting in formation of a cellular spore
NC3_00530	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NC3_00540	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NC3_00550	COG0193	aminoacyl-tRNA hydrolase activity
NC3_00570	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NC3_00580	COG2002	toxin-antitoxin pair type II binding
NC3_00590	COG2244	polysaccharide biosynthetic process
NC3_00600	COG3956	TIGRFAM MazG family protein
NC3_00610	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NC3_00640	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NC3_00650	COG1098	S1 RNA binding domain
NC3_00660	COG2208	phosphoserine phosphatase activity
NC3_00670	COG2304	oxidoreductase activity
NC3_00680	COG0515	serine threonine protein kinase
NC3_00690	COG0037	tRNA processing
NC3_00700	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NC3_00710	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NC3_00720	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NC3_00730	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NC3_00740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NC3_00750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NC3_00760	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NC3_00770	COG0512	Glutamine amidotransferase of anthranilate synthase
NC3_00780	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NC3_00790	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NC3_00800	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NC3_00810	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NC3_00820	COG1396	sequence-specific DNA binding
NC3_00830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NC3_00840	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NC3_00850	COG4463	regulation of RNA biosynthetic process
NC3_00860	COG3880	PFAM UvrB UvrC protein
NC3_00870	COG3869	Catalyzes the specific phosphorylation of arginine residues in
NC3_00880	COG0542	response to heat
NC3_00890	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NC3_00900	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NC3_00910	COG4956	integral membrane protein (PIN domain superfamily)
NC3_00920	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NC3_00930	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NC3_00940	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NC3_00950	COG1045	serine acetyltransferase
NC3_00960	COG0215	cysteine-tRNA ligase activity
NC3_00970	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NC3_00980	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NC3_00990	COG3688	RNA-binding protein containing a PIN domain
NC3_01000	COG1595	DNA-templated transcription, initiation
NC3_01010	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NC3_01020	COG0250	Participates in transcription elongation, termination and antitermination
NC3_01040	COG0081	regulation of translation
NC3_01050	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NC3_01060	COG0222	ribosome binding
NC3_01070	COG2813	Specifically methylates the guanine in position
NC3_01080	COG0085	RNA polymerase activity
NC3_01090	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NC3_01100	COG1358	cellular component organization or biogenesis
NC3_01110	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NC3_01120	COG0049	tRNA binding
NC3_01130	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NC3_01140	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NC3_01150	COG0596	Alpha beta hydrolase
NC3_01170	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NC3_01180	COG0088	Forms part of the polypeptide exit tunnel
NC3_01190	COG0089	rRNA binding
NC3_01200	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NC3_01210	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NC3_01220	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NC3_01230	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NC3_01240	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NC3_01250	COG0255	Belongs to the universal ribosomal protein uL29 family
NC3_01260	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NC3_01270	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NC3_01280	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NC3_01290	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NC3_01300	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NC3_01310	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NC3_01320	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NC3_01330	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NC3_01340	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NC3_01350	COG1841	ribosomal large subunit assembly
NC3_01360	COG0200	Binds to the 23S rRNA
NC3_01370	COG0201	protein transport
NC3_01380	COG0563	adenylate kinase activity
NC3_01390	COG0024	Methionine aminopeptidase
NC3_01400	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NC3_01410	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NC3_01420	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NC3_01430	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NC3_01440	COG0202	RNA polymerase activity
NC3_01450	COG0203	ribosomal protein L17
NC3_01460	COG1122	ATPase activity
NC3_01470	COG1122	ATPase activity
NC3_01480	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NC3_01490	COG0101	tRNA pseudouridine synthase activity
NC3_01500	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NC3_01510	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NC3_01560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NC3_01620	COG0860	N-Acetylmuramoyl-L-alanine amidase
NC3_01630	COG0489	protein tyrosine kinase activity
NC3_01650	COG2194	sulfuric ester hydrolase activity
NC3_01660	COG0726	polysaccharide deacetylase
NC3_01690	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NC3_01700	COG0659	secondary active sulfate transmembrane transporter activity
NC3_01710	COG0385	Bile acid
NC3_01720	COG3876	Protein conserved in bacteria
NC3_01730	COG1472	Belongs to the glycosyl hydrolase 3 family
NC3_01740	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NC3_01750	COG1263	PTS System
NC3_01750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NC3_01760	COG1737	Transcriptional regulator
NC3_01770	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NC3_01790	COG1595	DNA-templated transcription, initiation
NC3_01800	COG5662	AntiSigma factor
NC3_01810	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NC3_01820	COG4856	YbbR-like protein
NC3_01830	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NC3_01840	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NC3_01920	COG1131	(ABC) transporter
NC3_01940	COG1136	(ABC) transporter
NC3_01960	COG1695	Transcriptional regulator
NC3_01980	COG1131	(ABC) transporter
NC3_02000	COG1413	lyase activity
NC3_02010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NC3_02030	COG2311	Membrane
NC3_02070	COG1476	TRANSCRIPTIONal
NC3_02090	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NC3_02100	COG2207	Transcriptional regulator
NC3_02110	COG1309	transcriptional regulator
NC3_02140	COG1113	amino acid transport
NC3_02150	COG0584	glycerophosphoryl diester phosphodiesterase
NC3_02160	COG2271	Major facilitator Superfamily
NC3_02180	COG1331	Highly conserved protein containing a thioredoxin domain
NC3_02200	COG0640	Transcriptional regulator
NC3_02230	COG1937	Protein conserved in bacteria
NC3_02240	COG2210	Belongs to the sulfur carrier protein TusA family
NC3_02260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NC3_02260	COG0425	Belongs to the sulfur carrier protein TusA family
NC3_02270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NC3_02270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NC3_02280	COG0425	Belongs to the sulfur carrier protein TusA family
NC3_02290	COG0730	response to heat
NC3_02310	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NC3_02320	COG2814	Major facilitator Superfamily
NC3_02350	COG1846	Transcriptional regulator
NC3_02360	COG1683	Conserved Protein
NC3_02380	COG0656	L-ascorbic acid biosynthetic process
NC3_02390	COG0371	Dehydrogenase
NC3_02400	COG1054	Belongs to the UPF0176 family
NC3_02410	COG0531	amino acid
NC3_02430	COG3711	transcriptional antiterminator
NC3_02440	COG2190	(PTS) system
NC3_02440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NC3_02440	COG1263	PTS System
NC3_02450	COG2723	6-phospho-beta-galactosidase activity
NC3_02480	COG3711	transcriptional antiterminator
NC3_02480	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NC3_02490	COG1940	carbohydrate kinase activity
NC3_02500	COG0383	alpha-mannosidase activity
NC3_02510	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NC3_02520	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NC3_02530	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NC3_02530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NC3_02540	COG1404	Belongs to the peptidase S8 family
NC3_02570	COG0833	amino acid
NC3_02580	COG2040	homocysteine
NC3_02590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NC3_02600	COG1695	Transcriptional regulator
NC3_02630	COG2814	Major facilitator Superfamily
NC3_02640	COG0456	acetyltransferase
NC3_02670	COG1404	Belongs to the peptidase S8 family
NC3_02690	COG1309	transcriptional regulator
NC3_02700	COG1917	Cupin 2, conserved barrel domain protein
NC3_02710	COG1063	alcohol dehydrogenase
NC3_02720	COG1846	Transcriptional regulator
NC3_02730	COG0318	PFAM AMP-dependent synthetase and ligase
NC3_02740	COG0531	amino acid
NC3_02760	COG0596	Alpha beta hydrolase
NC3_02770	COG1115	amino acid carrier protein
NC3_02780	COG2066	Belongs to the glutaminase family
NC3_02790	COG4191	Histidine kinase
NC3_02800	COG0784	Response regulator, receiver
NC3_02810	COG3012	SEC-C Motif Domain Protein
NC3_02810	COG1405	negative regulation of cell septum assembly
NC3_02830	COG0667	Aldo Keto reductase
NC3_02840	COG3290	protein histidine kinase activity
NC3_02850	COG3279	Response regulator of the LytR AlgR family
NC3_02860	COG4555	ABC transporter
NC3_02870	COG1668	transmembrane transport
NC3_02920	COG3773	Cell wall hydrolase
NC3_02930	COG1028	Short-chain dehydrogenase reductase Sdr
NC3_02950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NC3_02960	COG2310	stress, protein
NC3_02970	COG2310	stress, protein
NC3_02980	COG2310	stress, protein
NC3_02990	COG0861	Integral membrane protein TerC family
NC3_03050	COG3853	Toxic anion resistance protein (TelA)
NC3_03060	COG4175	Glycine betaine
NC3_03060	COG0517	IMP dehydrogenase activity
NC3_03070	COG4176	ABC-type proline glycine betaine transport system permease component
NC3_03080	COG2113	Glycine betaine
NC3_03110	COG1473	amidohydrolase
NC3_03120	COG1288	antiporter activity
NC3_03130	COG0039	L-malate dehydrogenase activity
NC3_03140	COG1620	l-lactate permease
NC3_03150	COG1609	Transcriptional regulator
NC3_03160	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NC3_03170	COG0561	phosphatase activity
NC3_03180	COG0673	inositol 2-dehydrogenase activity
NC3_03190	COG0738	Major facilitator superfamily
NC3_03200	COG1280	lysine exporter protein (LysE YggA)
NC3_03220	COG3403	YqcI/YcgG family
NC3_03230	COG1113	amino acid transport
NC3_03240	COG3665	Urea carboxylase-associated protein
NC3_03250	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NC3_03270	COG1012	belongs to the aldehyde dehydrogenase family
NC3_03280	COG0710	3-dehydroquinate dehydratase activity
NC3_03290	COG0028	Belongs to the TPP enzyme family
NC3_03310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NC3_03320	COG2271	Major facilitator Superfamily
NC3_03350	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NC3_03360	COG2226	methyltransferase
NC3_03370	COG0583	DNA-binding transcription factor activity
NC3_03380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NC3_03390	COG3458	cephalosporin-C deacetylase activity
NC3_03410	COG3541	Predicted nucleotidyltransferase
NC3_03420	COG0506	proline dehydrogenase activity
NC3_03430	COG1012	belongs to the aldehyde dehydrogenase family
NC3_03440	COG2508	Transcriptional regulator
NC3_03450	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NC3_03460	COG0765	amino acid transport
NC3_03470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NC3_03500	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NC3_03510	COG1522	sequence-specific DNA binding
NC3_03520	COG2746	aminoglycoside 3-N-acetyltransferase activity
NC3_03540	COG0840	transmembrane signaling receptor activity
NC3_03540	COG3290	protein histidine kinase activity
NC3_03550	COG3209	COG3209 Rhs family protein
NC3_03590	COG3842	ATPase activity
NC3_03600	COG1176	ABC-type spermidine putrescine transport system, permease component I
NC3_03620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NC3_03630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NC3_03640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NC3_03670	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
NC3_03680	COG4555	ABC transporter
NC3_03710	COG0697	spore germination
NC3_03720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NC3_03740	COG2207	Transcriptional regulator
NC3_03740	COG3708	Transcriptional regulator
NC3_03760	COG2364	Membrane
NC3_03770	COG1126	abc transporter atp-binding protein
NC3_03780	COG0765	amino acid transport
NC3_03790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NC3_03800	COG0412	Dienelactone hydrolase
NC3_03810	COG0833	amino acid
NC3_03820	COG3104	oligopeptide transport
NC3_03830	COG5434	Belongs to the glycosyl hydrolase 28 family
NC3_03840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NC3_03850	COG0456	acetyltransferase
NC3_03860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NC3_03870	COG0765	amino acid transport
NC3_03880	COG1126	abc transporter atp-binding protein
NC3_03890	COG1473	amidohydrolase
NC3_03900	COG2079	MmgE PrpD family protein
NC3_03910	COG0745	RESPONSE REGULATOR receiver
NC3_03920	COG3850	Histidine kinase
NC3_03920	COG5002	protein histidine kinase activity
NC3_03930	COG1366	Belongs to the anti-sigma-factor antagonist family
NC3_03940	COG0527	aspartate kinase activity
NC3_03950	COG2814	Major facilitator Superfamily
NC3_03960	COG1309	transcriptional regulator
NC3_03980	COG0640	Transcriptional regulator
NC3_04000	COG0583	DNA-binding transcription factor activity
NC3_04010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NC3_04020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NC3_04030	COG0531	amino acid
NC3_04040	COG1012	belongs to the aldehyde dehydrogenase family
NC3_04050	COG2249	NAD(P)H dehydrogenase (quinone) activity
NC3_04060	COG4549	nuclear export factor GLE1
NC3_04070	COG2372	response to copper ion
NC3_04070	COG1276	copper resistance
NC3_04080	COG2213	PTS system mannitol-specific
NC3_04090	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NC3_04100	COG0246	Mannitol dehydrogenase
NC3_04110	COG0840	transmembrane signaling receptor activity
NC3_04180	COG0346	lactoylglutathione lyase activity
NC3_04200	COG0561	phosphatase activity
NC3_04210	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NC3_04220	COG1914	H( )-stimulated, divalent metal cation uptake system
NC3_04230	COG4336	lyase activity
NC3_04240	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NC3_04250	COG1984	allophanate hydrolase subunit 2
NC3_04260	COG1414	Transcriptional regulator
NC3_04270	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NC3_04280	COG2755	lipolytic protein G-D-S-L family
NC3_04300	COG3711	transcriptional antiterminator
NC3_04310	COG2226	methyltransferase
NC3_04320	COG1028	Short-chain dehydrogenase reductase Sdr
NC3_04330	COG3871	stress protein (general stress protein 26)
NC3_04360	COG2814	Major facilitator Superfamily
NC3_04370	COG1802	Transcriptional regulator
NC3_04380	COG2207	Transcriptional regulator
NC3_04380	COG1917	Cupin 2, conserved barrel domain protein
NC3_04390	COG0697	spore germination
NC3_04400	COG0473	3-isopropylmalate dehydrogenase activity
NC3_04410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NC3_04410	COG0551	DNA topoisomerase type I activity
NC3_04420	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
NC3_04430	COG3706	GGDEF domain
NC3_04440	COG5298	Protein conserved in bacteria
NC3_04450	COG1215	transferase activity, transferring glycosyl groups
NC3_04480	COG0531	amino acid
NC3_04490	COG0028	Belongs to the TPP enzyme family
NC3_04500	COG5444	nuclease activity
NC3_04540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NC3_04550	COG1914	H( )-stimulated, divalent metal cation uptake system
NC3_04560	COG2261	transglycosylase associated protein
NC3_04570	COG2217	Heavy metal translocating P-type atpase
NC3_04580	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NC3_04590	COG3290	protein histidine kinase activity
NC3_04600	COG4565	transcriptional regulatory protein
NC3_04620	COG1301	dicarboxylic acid transport
NC3_04630	COG0628	permease
NC3_04640	COG1301	dicarboxylic acid transport
NC3_04650	COG1131	(ABC) transporter
NC3_04660	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NC3_04690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NC3_04700	COG1181	Belongs to the D-alanine--D-alanine ligase family
NC3_04710	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NC3_04740	COG0513	Belongs to the DEAD box helicase family
NC3_04750	COG3402	PFAM membrane-flanked domain
NC3_04760	COG3428	Bacterial PH domain
NC3_04770	COG0705	Rhomboid family
NC3_04780	COG0736	holo-[acyl-carrier-protein] synthase activity
NC3_04790	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NC3_04800	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NC3_04810	COG0864	Transcriptional regulator
NC3_04820	COG2337	Toxic component of a toxin-antitoxin (TA) module
NC3_04830	COG1366	Belongs to the anti-sigma-factor antagonist family
NC3_04840	COG1366	Belongs to the anti-sigma-factor antagonist family
NC3_04850	COG2172	sigma factor antagonist activity
NC3_04860	COG2208	phosphoserine phosphatase activity
NC3_04870	COG1366	Belongs to the anti-sigma-factor antagonist family
NC3_04880	COG2172	sigma factor antagonist activity
NC3_04890	COG1191	sigma factor activity
NC3_04900	COG2208	phosphoserine phosphatase activity
NC3_04910	COG2183	response to ionizing radiation
NC3_04920	COG3091	SprT-like family
NC3_04930	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NC3_04940	COG0022	dehydrogenase e1 component
NC3_04950	COG0508	dehydrogenase complex catalyzes the overall conversion of
NC3_04960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NC3_04970	COG3284	Transcriptional regulator
NC3_04980	COG0433	COG0433 Predicted ATPase
NC3_04990	COG5644	endopeptidase inhibitor activity
NC3_05040	COG1278	Cold shock
NC3_05050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NC3_05050	COG2190	(PTS) system
NC3_05050	COG1263	PTS System
NC3_05060	COG3394	polysaccharide catabolic process
NC3_05070	COG3711	transcriptional antiterminator
NC3_05080	COG1064	alcohol dehydrogenase
NC3_05090	COG0789	Transcriptional regulator
NC3_05130	COG0477	Major facilitator Superfamily
NC3_05140	COG0657	acetylesterase activity
NC3_05160	COG4221	oxidoreductase activity
NC3_05170	COG0252	asparaginase activity
NC3_05180	COG2267	carboxylic ester hydrolase activity
NC3_05220	COG2814	Major facilitator Superfamily
NC3_05250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NC3_05300	COG1309	transcriptional regulator
NC3_05310	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NC3_05320	COG1846	Transcriptional regulator
NC3_05330	COG0778	Nitroreductase
NC3_05360	COG1396	sequence-specific DNA binding
NC3_05380	COG0456	acetyltransferase
NC3_05400	COG4122	O-methyltransferase activity
NC3_05420	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NC3_05430	COG0697	spore germination
NC3_05450	COG1301	dicarboxylic acid transport
NC3_05470	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NC3_05480	COG0802	atpase or kinase
NC3_05490	COG1214	PFAM Peptidase M22, glycoprotease
NC3_05500	COG0456	acetyltransferase
NC3_05510	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NC3_05520	COG0488	(ABC) transporter
NC3_05530	COG0315	cyclic pyranopterin monophosphate synthase activity
NC3_05540	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NC3_05550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NC3_05560	COG0805	protein transport
NC3_05590	COG1266	CAAX protease self-immunity
NC3_05600	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NC3_05610	COG0459	protein refolding
NC3_05620	COG1846	Transcriptional regulator
NC3_05630	COG2808	Putative FMN-binding domain
NC3_05640	COG1876	peptidase activity
NC3_05690	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NC3_05700	COG0823	Involved in the tonB-independent uptake of proteins
NC3_05720	COG2132	Multicopper oxidase
NC3_05730	COG1113	amino acid transport
NC3_05740	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NC3_05750	COG0714	Associated with various cellular activities
NC3_05760	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
NC3_05770	COG1305	Transglutaminase-like
NC3_05780	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NC3_05780	COG0519	Catalyzes the synthesis of GMP from XMP
NC3_05790	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NC3_05810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NC3_05830	COG2207	Transcriptional regulator
NC3_05840	COG0519	Catalyzes the synthesis of GMP from XMP
NC3_05840	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NC3_05860	COG0326	Molecular chaperone. Has ATPase activity
NC3_05910	COG1595	DNA-templated transcription, initiation
NC3_05940	COG2814	Major facilitator Superfamily
NC3_05950	COG0583	DNA-binding transcription factor activity
NC3_05960	COG2252	PERMEase
NC3_05980	COG5583	Uncharacterized small protein (DUF2292)
NC3_05990	COG3064	Membrane
NC3_06000	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
NC3_06020	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NC3_06030	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NC3_06040	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NC3_06050	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NC3_06060	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NC3_06070	COG0047	phosphoribosylformylglycinamidine synthase activity
NC3_06080	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NC3_06090	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NC3_06100	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NC3_06110	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NC3_06120	COG0138	bifunctional purine biosynthesis protein purh
NC3_06130	COG0151	Belongs to the GarS family
NC3_06170	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NC3_06180	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NC3_06190	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NC3_06200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NC3_06220	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NC3_06230	COG4496	protein, YerC YecD
NC3_06260	COG0069	glutamate synthase activity
NC3_06290	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NC3_06300	COG0210	DNA helicase
NC3_06310	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NC3_06320	COG4851	CamS sex pheromone cAM373 precursor
NC3_06330	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NC3_06340	COG1285	pathogenesis
NC3_06350	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NC3_06360	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NC3_06370	COG0154	amidase activity
NC3_06380	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NC3_06390	COG1309	transcriptional regulator
NC3_06400	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NC3_06410	COG1957	nucleoside hydrolase
NC3_06420	COG1597	lipid kinase activity
NC3_06430	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NC3_06440	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NC3_06470	COG1959	2 iron, 2 sulfur cluster binding
NC3_06480	COG0492	ferredoxin-NADP+ reductase activity
NC3_06510	COG1486	melibiose metabolic process
NC3_06530	COG2211	Major facilitator Superfamily
NC3_06590	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NC3_06600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NC3_06610	COG1442	glycosyl transferase family 8
NC3_06620	COG1216	Glycosyl transferase, family 2
NC3_06630	COG1442	glycosyl transferase family 8
NC3_06640	COG2223	nitrite transmembrane transporter activity
NC3_06660	COG0471	metal ion transport
NC3_06690	COG0071	Belongs to the small heat shock protein (HSP20) family
NC3_06720	COG0531	amino acid
NC3_06730	COG0457	Tetratricopeptide repeat
NC3_06730	COG0463	Glycosyl transferase, family 2
NC3_06740	COG0488	(ABC) transporter
NC3_06750	COG1469	GTP cyclohydrolase I activity
NC3_06760	COG0789	Transcriptional regulator
NC3_06770	COG2814	Major facilitator Superfamily
NC3_06780	COG0488	(ABC) transporter
NC3_06790	COG0513	Belongs to the DEAD box helicase family
NC3_06800	COG2130	NADP-dependent
NC3_06840	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NC3_06840	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NC3_06850	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NC3_06880	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NC3_06880	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NC3_06900	COG3290	protein histidine kinase activity
NC3_06910	COG4565	transcriptional regulatory protein
NC3_06920	COG3181	Tripartite tricarboxylate transporter family receptor
NC3_06930	COG2851	Citrate transporter
NC3_06950	COG3479	Phenolic acid decarboxylase
NC3_06960	COG1695	Transcriptional regulator
NC3_06970	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NC3_06990	COG1254	Belongs to the acylphosphatase family
NC3_07000	COG2258	MOSC domain
NC3_07030	COG0024	Methionine aminopeptidase
NC3_07040	COG1263	PTS System
NC3_07040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NC3_07050	COG3739	integral membrane protein
NC3_07090	COG1368	sulfuric ester hydrolase activity
NC3_07100	COG0076	glutamate decarboxylase activity
NC3_07130	COG1263	PTS System
NC3_07130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NC3_07140	COG0366	Alpha amylase catalytic
NC3_07150	COG2188	Transcriptional regulator
NC3_07170	COG0737	Belongs to the 5'-nucleotidase family
NC3_07180	COG0693	protein deglycase activity
NC3_07190	COG4840	Belongs to the UPF0435 family
NC3_07200	COG1115	amino acid carrier protein
NC3_07210	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NC3_07220	COG4980	gas vesicle protein
NC3_07230	COG1295	ribonuclease BN
NC3_07250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NC3_07260	COG0477	Major facilitator Superfamily
NC3_07280	COG0387	Pfam Sodium calcium exchanger
NC3_07300	COG0217	transcriptional regulatory protein
NC3_07320	COG0668	transmembrane transport
NC3_07330	COG0535	radical SAM domain protein
NC3_07350	COG0726	polysaccharide deacetylase
NC3_07370	COG0598	Magnesium transport protein CorA
NC3_07390	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NC3_07400	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NC3_07430	COG0583	DNA-binding transcription factor activity
NC3_07440	COG1942	4-Oxalocrotonate Tautomerase
NC3_07450	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NC3_07460	COG0789	Transcriptional regulator
NC3_07470	COG2814	Major facilitator Superfamily
NC3_07500	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NC3_07600	COG2076	Multidrug Resistance protein
NC3_07610	COG2076	Multidrug Resistance protein
NC3_07620	COG1309	transcriptional regulator
NC3_07640	COG4637	Psort location Cytoplasmic, score
NC3_07650	COG2755	lipolytic protein G-D-S-L family
NC3_07660	COG0492	ferredoxin-NADP+ reductase activity
NC3_07670	COG2169	Transcriptional regulator
NC3_07680	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NC3_07690	COG1132	(ABC) transporter
NC3_07700	COG1742	UPF0060 membrane protein
NC3_07710	COG1595	DNA-templated transcription, initiation
NC3_07740	COG2318	DinB family
NC3_07760	COG1846	Transcriptional regulator
NC3_07770	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NC3_07770	COG0392	lysyltransferase activity
NC3_07810	COG0778	Nitroreductase
NC3_07830	COG1090	epimerase
NC3_07840	COG2137	regulation of response to DNA damage stimulus
NC3_07890	COG0463	Glycosyl transferase, family 2
NC3_07900	COG4485	Bacterial membrane protein, YfhO
NC3_07910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NC3_07930	COG2140	Oxalate decarboxylase
NC3_07950	COG1191	sigma factor activity
NC3_07970	COG1988	membrane-bound metal-dependent
NC3_07980	COG1194	a g-specific adenine glycosylase
NC3_08000	COG1028	Short-chain dehydrogenase reductase Sdr
NC3_08030	COG3557	Belongs to the UPF0374 family
NC3_08040	COG1132	(ABC) transporter
NC3_08050	COG0444	Belongs to the ABC transporter superfamily
NC3_08060	COG4608	Belongs to the ABC transporter superfamily
NC3_08070	COG0747	negative chemotaxis
NC3_08080	COG0601	transmembrane transport
NC3_08090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NC3_08100	COG4129	membrane
NC3_08110	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NC3_08120	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NC3_08130	COG0735	belongs to the Fur family
NC3_08250	COG1368	sulfuric ester hydrolase activity
NC3_08260	COG0681	Belongs to the peptidase S26 family
NC3_08270	COG2873	o-acetylhomoserine
NC3_08290	COG1116	anion transmembrane transporter activity
NC3_08300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NC3_08310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NC3_08320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NC3_08340	COG1131	(ABC) transporter
NC3_08390	COG3382	B3 4 domain protein
NC3_08400	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NC3_08420	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NC3_08430	COG2766	serine protein kinase
NC3_08440	COG2718	Belongs to the UPF0229 family
NC3_08460	COG1566	PFAM secretion protein HlyD family protein
NC3_08470	COG2814	Major facilitator Superfamily
NC3_08480	COG0655	NAD(P)H dehydrogenase (quinone) activity
NC3_08500	COG1278	Cold shock
NC3_08510	COG3706	GGDEF domain
NC3_08560	COG5577	PFAM Coat F domain
NC3_08570	COG5002	protein histidine kinase activity
NC3_08580	COG0737	Belongs to the 5'-nucleotidase family
NC3_08580	COG1525	nuclease
NC3_08580	COG4085	toxin activity
NC3_08590	COG3764	Sortase (surface protein transpeptidase)
NC3_08600	COG0564	pseudouridine synthase activity
NC3_08620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NC3_08630	COG3153	acetyltransferase
NC3_08630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NC3_08670	COG3835	regulator
NC3_08680	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NC3_08690	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NC3_08700	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NC3_08710	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NC3_08720	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NC3_08730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NC3_08740	COG4585	Histidine kinase
NC3_08740	COG2203	Gaf domain
NC3_08750	COG2197	response regulator
NC3_08790	COG0753	catalase activity
NC3_08800	COG1959	2 iron, 2 sulfur cluster binding
NC3_08810	COG1017	nitric oxide dioxygenase activity
NC3_08810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NC3_08820	COG2719	SpoVR family
NC3_08830	COG1785	Belongs to the alkaline phosphatase family
NC3_08840	COG0791	NLP P60 protein
NC3_08840	COG1388	LysM domain
NC3_08850	COG0531	amino acid
NC3_08880	COG1595	DNA-templated transcription, initiation
NC3_08890	COG0204	Acyl-transferase
NC3_08900	COG1253	flavin adenine dinucleotide binding
NC3_08910	COG0789	Transcriptional regulator
NC3_08920	COG1253	flavin adenine dinucleotide binding
NC3_08950	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NC3_08960	COG0584	glycerophosphoryl diester phosphodiesterase
NC3_08970	COG0668	transmembrane transport
NC3_08980	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NC3_08990	COG0726	polysaccharide deacetylase
NC3_09000	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NC3_09010	COG0589	response to stress
NC3_09020	COG1132	(ABC) transporter
NC3_09030	COG1132	(ABC) transporter
NC3_09040	COG0702	epimerase
NC3_09060	COG3842	ATPase activity
NC3_09070	COG2508	Transcriptional regulator
NC3_09090	COG0189	ligase activity
NC3_09100	COG0189	ligase activity
NC3_09110	COG4399	Belongs to the UPF0754 family
NC3_09120	COG3679	Belongs to the UPF0342 family
NC3_09130	COG0561	phosphatase activity
NC3_09140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NC3_09160	COG0475	glutathione-regulated potassium exporter activity
NC3_09170	COG0490	domain, Protein
NC3_09190	COG1024	Enoyl-CoA hydratase
NC3_09210	COG0420	3'-5' exonuclease activity
NC3_09220	COG4717	serine-type aminopeptidase activity
NC3_09230	COG3481	metal-dependent phosphohydrolase, HD sub domain
NC3_09250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NC3_09280	COG1846	Transcriptional regulator
NC3_09290	COG4980	gas vesicle protein
NC3_09320	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NC3_09330	COG0537	adenosine 5'-monophosphoramidase activity
NC3_09340	COG1131	(ABC) transporter
NC3_09350	COG4473	ABC transporter
NC3_09370	COG1473	amidohydrolase
NC3_09390	COG2329	Antibiotic biosynthesis monooxygenase
NC3_09400	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NC3_09410	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NC3_09420	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NC3_09430	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NC3_09440	COG1309	transcriptional regulator
NC3_09450	COG1511	domain protein
NC3_09460	COG1363	Peptidase, m42
NC3_09470	COG1301	dicarboxylic acid transport
NC3_09490	COG1234	tRNA 3'-trailer cleavage
NC3_09500	COG0095	Lipoate-protein ligase
NC3_09510	COG0318	PFAM AMP-dependent synthetase and ligase
NC3_09530	COG0501	Belongs to the peptidase M48B family
NC3_09540	COG1404	Belongs to the peptidase S8 family
NC3_09550	COG0406	alpha-ribazole phosphatase activity
NC3_09560	COG0840	transmembrane signaling receptor activity
NC3_09570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NC3_09570	COG0723	plastoquinol--plastocyanin reductase activity
NC3_09580	COG1028	Short-chain dehydrogenase reductase Sdr
NC3_09600	COG4903	ComK protein
NC3_09630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NC3_09640	COG2814	Major facilitator Superfamily
NC3_09650	COG2732	(Barnase) inhibitor
NC3_09660	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NC3_09670	COG4605	iron ion homeostasis
NC3_09680	COG4604	ABC transporter, ATP-binding protein
NC3_09690	COG4607	ABC-type enterochelin transport system periplasmic component
NC3_09700	COG1316	TRANSCRIPTIONal
NC3_09730	COG0398	Pfam SNARE associated Golgi protein
NC3_09740	COG0681	Belongs to the peptidase S26 family
NC3_09750	COG3180	Ammonia monooxygenase
NC3_09790	COG2259	Doxx family
NC3_09800	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
NC3_09810	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NC3_09820	COG1074	ATP-dependent DNA helicase activity
NC3_09830	COG0420	3'-5' exonuclease activity
NC3_09840	COG0419	ATPase involved in DNA repair
NC3_09850	COG1403	HNH endonuclease
NC3_09930	COG5337	Spore coat protein CotH
NC3_09940	COG0179	Fumarylacetoacetate (FAA) hydrolase
NC3_09970	COG0367	asparagine synthase
NC3_10000	COG1562	ergosterol biosynthetic process
NC3_10010	COG0534	Mate efflux family protein
NC3_10020	COG1917	Cupin 2, conserved barrel domain protein
NC3_10020	COG2207	Transcriptional regulator
NC3_10070	COG0076	glutamate decarboxylase activity
NC3_10140	COG0646	methionine synthase
NC3_10140	COG1410	methionine synthase
NC3_10150	COG0646	methionine synthase
NC3_10150	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NC3_10160	COG1666	GTP binding
NC3_10170	COG2996	Protein conserved in bacteria
NC3_10180	COG1744	ABC transporter substrate-binding protein PnrA-like
NC3_10190	COG0840	transmembrane signaling receptor activity
NC3_10200	COG1307	EDD domain protein, DegV family
NC3_10210	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NC3_10250	COG0561	phosphatase activity
NC3_10260	COG1073	alpha beta
NC3_10270	COG2151	metal-sulfur cluster biosynthetic enzyme
NC3_10280	COG0277	FAD linked oxidase domain protein
NC3_10290	COG2271	Major facilitator Superfamily
NC3_10300	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NC3_10310	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NC3_10320	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NC3_10330	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NC3_10340	COG0505	Belongs to the CarA family
NC3_10350	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NC3_10360	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NC3_10380	COG2814	Major facilitator Superfamily
NC3_10400	COG2267	carboxylic ester hydrolase activity
NC3_10420	COG1744	ABC transporter substrate-binding protein PnrA-like
NC3_10460	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NC3_10470	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NC3_10480	COG5504	Zn-dependent protease
NC3_10490	COG0444	Belongs to the ABC transporter superfamily
NC3_10500	COG4608	Belongs to the ABC transporter superfamily
NC3_10520	COG0601	transmembrane transport
NC3_10530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NC3_10550	COG0180	Tryptophanyl-tRNA synthetase
NC3_10560	COG4166	transmembrane transport
NC3_10570	COG0601	transmembrane transport
NC3_10580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NC3_10590	COG0444	Belongs to the ABC transporter superfamily
NC3_10600	COG4608	Belongs to the ABC transporter superfamily
NC3_10620	COG0456	acetyltransferase
NC3_10630	COG1393	Belongs to the ArsC family
NC3_10640	COG0861	Integral membrane protein TerC family
NC3_10650	COG4862	establishment of competence for transformation
NC3_10660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NC3_10680	COG1164	Oligoendopeptidase f
NC3_10700	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NC3_10710	COG2346	COG2346, Truncated hemoglobins
NC3_10720	COG0741	lytic transglycosylase activity
NC3_10730	COG4116	CYTH
NC3_10750	COG2357	RelA SpoT domain protein
NC3_10760	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NC3_10770	COG0564	pseudouridine synthase activity
NC3_10780	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NC3_10790	COG0475	glutathione-regulated potassium exporter activity
NC3_10790	COG0569	domain protein
NC3_10800	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NC3_10810	COG0352	thiamine-phosphate diphosphorylase activity
NC3_10830	COG2104	thiamine diphosphate biosynthetic process
NC3_10840	COG2022	thiamine diphosphate biosynthetic process
NC3_10850	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NC3_10860	COG0351	phosphomethylpyrimidine kinase
NC3_10870	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NC3_10980	COG0210	DNA helicase
NC3_11000	COG2153	protein acetylation
NC3_11010	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NC3_11020	COG2382	esterase
NC3_11030	COG0626	cystathionine gamma-synthase activity
NC3_11040	COG0626	cystathionine gamma-synthase activity
NC3_11060	COG3409	Peptidoglycan-binding domain 1 protein
NC3_11060	COG5632	N-Acetylmuramoyl-L-alanine amidase
NC3_11170	COG0825	malonyl-CoA metabolic process
NC3_11200	COG0457	Tetratricopeptide repeat
NC3_11220	COG2153	protein acetylation
NC3_11230	COG2364	Membrane
NC3_11260	COG0300	oxidoreductase activity
NC3_11280	COG3173	Aminoglycoside phosphotransferase
NC3_11290	COG0583	DNA-binding transcription factor activity
NC3_11330	COG0583	DNA-binding transcription factor activity
NC3_11340	COG2807	transmembrane transport
NC3_11410	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NC3_11440	COG1309	transcriptional regulator
NC3_11460	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NC3_11470	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NC3_11510	COG4195	phage-related replication protein
NC3_11520	COG2856	Zn peptidase
NC3_11530	COG3409	Peptidoglycan-binding domain 1 protein
NC3_11530	COG5632	N-Acetylmuramoyl-L-alanine amidase
NC3_11570	COG0306	phosphate transporter
NC3_11580	COG1392	Phosphate transport regulator
NC3_11600	COG0405	Gamma-glutamyltransferase
NC3_11610	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NC3_11630	COG4208	sulfate ABC transporter
NC3_11640	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NC3_11660	COG3775	system Galactitol-specific IIC component
NC3_11690	COG1063	alcohol dehydrogenase
NC3_11700	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NC3_11710	COG0508	dehydrogenase complex catalyzes the overall conversion of
NC3_11710	COG0022	dehydrogenase e1 component
NC3_11720	COG0508	dehydrogenase complex catalyzes the overall conversion of
NC3_11730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NC3_11740	COG1028	Short-chain dehydrogenase reductase Sdr
NC3_11750	COG1028	Short-chain dehydrogenase reductase Sdr
NC3_11760	COG2390	Transcriptional regulator
NC3_11780	COG0531	amino acid
NC3_11790	COG0346	lactoylglutathione lyase activity
NC3_11800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NC3_11810	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NC3_11820	COG2362	D-Aminopeptidase
NC3_11830	COG0601	transmembrane transport
NC3_11840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NC3_11850	COG0444	Belongs to the ABC transporter superfamily
NC3_11860	COG4166	transmembrane transport
NC3_11880	COG1619	proteins homologs of microcin C7 resistance protein MccF
NC3_11890	COG4948	Mandelate Racemase Muconate Lactonizing
NC3_11900	COG0791	NLP P60 protein
NC3_11910	COG4608	Belongs to the ABC transporter superfamily
NC3_11920	COG1834	amidinotransferase
NC3_11930	COG1607	acyl-coa hydrolase
NC3_11940	COG1695	Transcriptional regulator
NC3_11970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NC3_11990	COG2076	Multidrug Resistance protein
NC3_12000	COG2076	Multidrug Resistance protein
NC3_12020	COG0788	formyltetrahydrofolate deformylase activity
NC3_12030	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NC3_12040	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NC3_12050	COG0457	Tetratricopeptide repeat
NC3_12070	COG1764	response to oxidative stress
NC3_12080	COG1846	Transcriptional regulator
NC3_12090	COG1764	response to oxidative stress
NC3_12100	COG0590	tRNA wobble adenosine to inosine editing
NC3_12110	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NC3_12120	COG1404	Belongs to the peptidase S8 family
NC3_12150	COG0745	RESPONSE REGULATOR receiver
NC3_12160	COG5002	protein histidine kinase activity
NC3_12160	COG3850	Histidine kinase
NC3_12170	COG3212	peptidase
NC3_12180	COG3212	peptidase
NC3_12210	COG2239	Acts as a magnesium transporter
NC3_12230	COG0583	DNA-binding transcription factor activity
NC3_12250	COG0789	Transcriptional regulator
NC3_12280	COG1846	Transcriptional regulator
NC3_12290	COG3300	MHYT domain
NC3_12290	COG5001	Diguanylate cyclase
NC3_12300	COG0586	Pfam SNARE associated Golgi protein
NC3_12310	COG0861	Integral membrane protein TerC family
NC3_12320	COG1191	sigma factor activity
NC3_12360	COG0501	Belongs to the peptidase M48B family
NC3_12370	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NC3_12380	COG2323	membrane
NC3_12410	COG3594	Acyltransferase
NC3_12420	COG5002	protein histidine kinase activity
NC3_12430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NC3_12450	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NC3_12460	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NC3_12470	COG0436	Aminotransferase
NC3_12480	COG1850	ribulose-bisphosphate carboxylase activity
NC3_12490	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NC3_12500	COG0235	Class ii aldolase
NC3_12510	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NC3_12530	COG3852	Histidine kinase
NC3_12540	COG1846	Transcriptional regulator
NC3_12550	COG1360	Flagellar Motor Protein
NC3_12560	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NC3_12570	COG0542	response to heat
NC3_12580	COG3949	Membrane
NC3_12590	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NC3_12600	COG0720	synthase
NC3_12610	COG0602	queuosine metabolic process
NC3_12620	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NC3_12630	COG1733	regulation of RNA biosynthetic process
NC3_12640	COG1028	Short-chain dehydrogenase reductase Sdr
NC3_12660	COG4873	Protein conserved in bacteria
NC3_12680	COG3773	Cell wall hydrolase
NC3_12690	COG2244	polysaccharide biosynthetic process
NC3_12700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NC3_12710	COG2217	Heavy metal translocating P-type atpase
NC3_12720	COG0006	proline dipeptidase activity
NC3_12740	COG1609	Transcriptional regulator
NC3_12750	COG3711	transcriptional antiterminator
NC3_12760	COG1263	PTS System
NC3_12760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NC3_12760	COG2190	(PTS) system
NC3_12770	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NC3_12780	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NC3_12800	COG1533	DNA photolyase activity
NC3_12810	COG0840	transmembrane signaling receptor activity
NC3_12830	COG2084	Dehydrogenase
NC3_12840	COG2340	Cysteine-rich secretory protein family
NC3_12850	COG0768	penicillin binding
NC3_12860	COG4191	Histidine kinase
NC3_12870	COG0436	Aminotransferase
NC3_12880	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NC3_12900	COG1714	RDD family
NC3_12920	COG0784	Response regulator, receiver
NC3_12920	COG0835	chemotaxis
NC3_12940	COG0697	spore germination
NC3_12950	COG0697	spore germination
NC3_12980	COG2814	Major facilitator Superfamily
NC3_12990	COG1376	ErfK ybiS ycfS ynhG family protein
NC3_13000	COG1408	metallophosphoesterase
NC3_13010	COG1028	Short-chain dehydrogenase reductase Sdr
NC3_13020	COG2200	EAL domain
NC3_13030	COG3546	catalase activity
NC3_13040	COG4703	Protein of unknown function (DUF1797)
NC3_13050	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
NC3_13070	COG0517	IMP dehydrogenase activity
NC3_13080	COG0583	DNA-binding transcription factor activity
NC3_13100	COG0716	FMN binding
NC3_13120	COG0716	FMN binding
NC3_13130	COG2171	N-acyltransferase activity
NC3_13140	COG1473	amidohydrolase
NC3_13160	COG0668	transmembrane transport
NC3_13170	COG0450	alkyl hydroperoxide reductase
NC3_13180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NC3_13210	COG0746	molybdenum cofactor guanylyltransferase activity
NC3_13220	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NC3_13230	COG0303	'Molybdopterin
NC3_13240	COG1763	Mo-molybdopterin cofactor biosynthetic process
NC3_13250	COG0314	molybdopterin synthase activity
NC3_13260	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NC3_13290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NC3_13300	COG1136	(ABC) transporter
NC3_13310	COG0577	efflux transmembrane transporter activity
NC3_13320	COG1349	DNA-binding transcription factor activity
NC3_13330	COG1105	Belongs to the carbohydrate kinase PfkB family
NC3_13340	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NC3_13340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NC3_13340	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NC3_13350	COG0681	Belongs to the peptidase S26 family
NC3_13370	COG0488	(ABC) transporter
NC3_13380	COG2309	aminopeptidase activity
NC3_13400	COG1077	Cell shape determining protein MreB Mrl
NC3_13410	COG2002	toxin-antitoxin pair type II binding
NC3_13420	COG3852	Histidine kinase
NC3_13430	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
NC3_13430	COG2105	PFAM AIG2 family protein
NC3_13440	COG0569	domain protein
NC3_13450	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NC3_13460	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NC3_13470	COG5503	Protein of unknown function (DUF1447)
NC3_13480	COG0561	phosphatase activity
NC3_13490	COG0242	peptide deformylase activity
NC3_13520	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NC3_13530	COG0022	dehydrogenase e1 component
NC3_13540	COG0508	dehydrogenase complex catalyzes the overall conversion of
NC3_13550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NC3_13560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NC3_13580	COG1982	Orn Lys Arg decarboxylase major
NC3_13590	COG4476	Belongs to the UPF0223 family
NC3_13600	COG4493	Belongs to the UPF0637 family
NC3_13620	COG0483	inositol monophosphate 1-phosphatase activity
NC3_13650	COG1595	DNA-templated transcription, initiation
NC3_13690	COG1217	gtp-binding protein TYPA
NC3_13710	COG4896	Protein conserved in bacteria
NC3_13730	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NC3_13740	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NC3_13750	COG2066	Belongs to the glutaminase family
NC3_13760	COG4838	Belongs to the UPF0358 family
NC3_13770	COG0772	Belongs to the SEDS family
NC3_13780	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NC3_13790	COG0415	Belongs to the DNA photolyase family
NC3_13800	COG1612	heme a metabolic process
NC3_13810	COG0109	protoheme IX farnesyltransferase activity
NC3_13820	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NC3_13820	COG2010	Cytochrome c
NC3_13830	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NC3_13840	COG1845	cytochrome c oxidase, subunit III
NC3_13850	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NC3_13860	COG3336	cytochrome c oxidase
NC3_13880	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
NC3_13890	COG2340	Cysteine-rich secretory protein family
NC3_13930	COG3679	Belongs to the UPF0342 family
NC3_13940	COG4471	UPF0298 protein
NC3_13950	COG0742	ribosomal rna small subunit methyltransferase
NC3_13960	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NC3_13970	COG3314	Sporulation integral membrane protein YlbJ
NC3_13980	COG1752	Esterase of the alpha-beta hydrolase superfamily
NC3_13990	COG3480	Lon protease (S16) C-terminal proteolytic domain
NC3_14020	COG1399	metal-binding, possibly nucleic acid-binding protein
NC3_14030	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NC3_14050	COG0454	-acetyltransferase
NC3_14060	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NC3_14070	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NC3_14080	COG2001	Belongs to the MraZ family
NC3_14090	COG0275	rRNA processing
NC3_14100	COG4839	cell division protein FtsL
NC3_14110	COG0768	penicillin binding
NC3_14120	COG0768	penicillin binding
NC3_14130	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NC3_14140	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NC3_14150	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NC3_14160	COG0772	Belongs to the SEDS family
NC3_14170	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NC3_14180	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NC3_14190	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NC3_14200	COG3879	Bacterial protein of unknown function (DUF881)
NC3_14210	COG3879	Bacterial protein of unknown function (DUF881)
NC3_14220	COG3856	small basic protein
NC3_14230	COG0849	cell division
NC3_14240	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NC3_14250	COG1404	Belongs to the peptidase S8 family
NC3_14250	COG4412	M6 family metalloprotease domain protein
NC3_14270	COG1191	sigma factor activity
NC3_14280	COG1191	sigma factor activity
NC3_14290	COG2390	Transcriptional regulator
NC3_14320	COG3730	PTS system glucitol sorbitol-specific
NC3_14330	COG3732	PTS system glucitol sorbitol-specific
NC3_14350	COG1119	ATPase activity
NC3_14360	COG1873	PFAM PRC-barrel domain
NC3_14370	COG1496	oxidoreductase activity
NC3_14380	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NC3_14390	COG1799	cell septum assembly
NC3_14400	COG0762	integral membrane protein
NC3_14410	COG2302	S4 RNA-binding domain
NC3_14420	COG3599	regulation of cell shape
NC3_14430	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NC3_14440	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NC3_14450	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NC3_14460	COG0564	pseudouridine synthase activity
NC3_14470	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NC3_14480	COG2233	PERMEase
NC3_14490	COG0540	Belongs to the ATCase OTCase family
NC3_14500	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NC3_14510	COG0505	Belongs to the CarA family
NC3_14520	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NC3_14530	COG0543	2 iron, 2 sulfur cluster binding
NC3_14540	COG0167	dihydroorotate dehydrogenase activity
NC3_14550	COG0284	orotidine-5'-phosphate decarboxylase activity
NC3_14560	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NC3_14580	COG0175	sulfate reduction
NC3_14590	COG0306	phosphate transporter
NC3_14600	COG2046	Belongs to the sulfate adenylyltransferase family
NC3_14610	COG0529	Catalyzes the synthesis of activated sulfate
NC3_14620	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NC3_14630	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
NC3_14640	COG1648	precorrin-2 dehydrogenase activity
NC3_14660	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NC3_14670	COG1561	YicC-like family, N-terminal region
NC3_14680	COG2052	Domain of unknown function (DUF370)
NC3_14690	COG0194	GDP metabolic process
NC3_14700	COG1758	RNA polymerase activity
NC3_14710	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NC3_14720	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NC3_14730	COG0242	peptide deformylase activity
NC3_14740	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NC3_14750	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NC3_14750	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NC3_14760	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NC3_14770	COG0631	protein serine/threonine phosphatase activity
NC3_14780	COG0515	serine threonine protein kinase
NC3_14780	COG2815	serine threonine protein kinase
NC3_14790	COG1162	GTPase activity
NC3_14800	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NC3_14810	COG1564	THIamine pyrophosphokinase
NC3_14820	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NC3_14830	COG1302	Protein conserved in bacteria
NC3_14840	COG1461	Dihydroxyacetone kinase
NC3_14850	COG1760	l-serine dehydratase
NC3_14860	COG1760	l-serine dehydratase
NC3_14870	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NC3_14880	COG1349	DNA-binding transcription factor activity
NC3_14890	COG0416	fatty acid biosynthetic process
NC3_14900	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NC3_14910	COG1028	Short-chain dehydrogenase reductase Sdr
NC3_14920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NC3_14940	COG1196	nuclear chromosome segregation
NC3_14950	COG0552	protein localization to endoplasmic reticulum
NC3_14960	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NC3_14970	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NC3_14980	COG0228	four-way junction DNA binding
NC3_14990	COG1837	Belongs to the UPF0109 family
NC3_15010	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NC3_15020	COG0336	Belongs to the RNA methyltransferase TrmD family
NC3_15030	COG0335	large ribosomal subunit rRNA binding
NC3_15040	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NC3_15050	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NC3_15070	COG2257	FlhB HrpN YscU SpaS Family
NC3_15080	COG0045	succinate-CoA ligase (ADP-forming) activity
NC3_15090	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NC3_15100	COG0758	DNA mediated transformation
NC3_15110	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NC3_15120	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NC3_15130	COG4974	Belongs to the 'phage' integrase family
NC3_15140	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NC3_15150	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NC3_15160	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NC3_15170	COG1815	bacterial-type flagellum-dependent cell motility
NC3_15180	COG1558	bacterial-type flagellum-dependent cell motility
NC3_15190	COG1677	Flagellar hook-basal body complex protein FliE
NC3_15200	COG1766	The M ring may be actively involved in energy transduction
NC3_15210	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NC3_15220	COG1317	bacterial-type flagellum organization
NC3_15230	COG1157	protein secretion by the type III secretion system
NC3_15240	COG2882	bacterial-type flagellum organization
NC3_15250	COG3334	PFAM MgtE intracellular
NC3_15260	COG3144	bacterial-type flagellum assembly
NC3_15270	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NC3_15280	COG4786	Flagellar basal body rod
NC3_15290	COG1582	Flagellar protein (FlbD)
NC3_15300	COG1580	Controls the rotational direction of flagella during chemotaxis
NC3_15310	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NC3_15320	COG1776	CheC inhibitor of MCP methylation
NC3_15320	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NC3_15330	COG2201	protein-glutamate methylesterase activity
NC3_15340	COG3190	flagellar
NC3_15350	COG1338	Plays a role in the flagellum-specific transport system
NC3_15360	COG1987	bacterial-type flagellum assembly
NC3_15370	COG1684	flagellar biosynthetic protein fliR
NC3_15380	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NC3_15390	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NC3_15400	COG1419	protein localization to endoplasmic reticulum
NC3_15410	COG0455	bacterial-type flagellum organization
NC3_15420	COG2201	protein-glutamate methylesterase activity
NC3_15430	COG2198	Histidine kinase
NC3_15430	COG0643	Histidine kinase
NC3_15440	COG0835	chemotaxis
NC3_15450	COG1776	CheC inhibitor of MCP methylation
NC3_15470	COG1191	sigma factor activity
NC3_15500	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NC3_15510	COG0528	UMP kinase activity
NC3_15520	COG0233	cytoplasmic translational termination
NC3_15530	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NC3_15540	COG4589	Belongs to the CDS family
NC3_15550	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NC3_15560	COG0750	zinc metalloprotease
NC3_15570	COG0442	prolyl-tRNA aminoacylation
NC3_15580	COG2176	DNA-directed DNA polymerase activity
NC3_15610	COG3693	PFAM glycoside hydrolase, family 10
NC3_15630	COG0779	Required for maturation of 30S ribosomal subunits
NC3_15640	COG0195	Participates in both transcription termination and antitermination
NC3_15650	COG2740	Nucleic-acid-binding protein implicated in transcription termination
NC3_15660	COG1358	cellular component organization or biogenesis
NC3_15670	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NC3_15680	COG1550	Protein conserved in bacteria
NC3_15690	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NC3_15700	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NC3_15710	COG0196	riboflavin kinase activity
NC3_15720	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NC3_15730	COG1185	polyribonucleotide nucleotidyltransferase activity
NC3_15740	COG0726	polysaccharide deacetylase
NC3_15750	COG0612	Peptidase, M16
NC3_15770	COG1873	PFAM PRC-barrel domain
NC3_15780	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NC3_15790	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NC3_15800	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NC3_15810	COG0527	aspartate kinase activity
NC3_15830	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NC3_15840	COG0740	serine-type endopeptidase activity
NC3_15860	COG4980	gas vesicle protein
NC3_15860	COG1674	ftsk spoiiie
NC3_15870	COG2188	Transcriptional regulator
NC3_15880	COG2814	Major facilitator Superfamily
NC3_15890	COG1033	growth of symbiont in host cell
NC3_15890	COG2409	Drug exporters of the RND superfamily
NC3_15900	COG0612	Peptidase, M16
NC3_15910	COG0612	Peptidase, M16
NC3_15930	COG1033	growth of symbiont in host cell
NC3_15930	COG2409	Drug exporters of the RND superfamily
NC3_15940	COG0300	oxidoreductase activity
NC3_15970	COG1426	Protein conserved in bacteria
NC3_15980	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NC3_15990	COG1058	Belongs to the CinA family
NC3_15990	COG1546	Belongs to the CinA family
NC3_16000	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NC3_16010	COG1418	mRNA catabolic process
NC3_16020	COG1692	metallophosphoesterase
NC3_16030	COG2359	stage V sporulation protein S
NC3_16040	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NC3_16050	COG1063	alcohol dehydrogenase
NC3_16060	COG0156	8-amino-7-oxononanoate synthase activity
NC3_16070	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NC3_16080	COG4550	Control of competence regulator ComK, YlbF/YmcA
NC3_16100	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NC3_16110	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NC3_16150	COG1329	Transcriptional regulator
NC3_16160	COG4195	phage-related replication protein
NC3_16170	COG0457	Tetratricopeptide repeat
NC3_16180	COG1404	Belongs to the peptidase S8 family
NC3_16190	COG4195	phage-related replication protein
NC3_16200	COG1764	response to oxidative stress
NC3_16260	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NC3_16270	COG1923	regulation of RNA biosynthetic process
NC3_16300	COG1780	Probably involved in ribonucleotide reductase function
NC3_16310	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NC3_16320	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NC3_16330	COG4112	unkown
NC3_16350	COG0464	growth
NC3_16360	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NC3_16370	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
NC3_16380	COG0789	Transcriptional regulator
NC3_16390	COG0174	glutamine synthetase
NC3_16420	COG5444	nuclease activity
NC3_16450	COG0494	nUDIX hydrolase
NC3_16470	COG0457	Tetratricopeptide repeat
NC3_16530	COG5444	nuclease activity
NC3_16580	COG5646	InterPro IPR014922
NC3_16630	COG0457	Tetratricopeptide repeat
NC3_16650	COG3619	membrane
NC3_16660	COG3285	dna ligase
NC3_16660	COG1793	dna ligase
NC3_16670	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NC3_16680	COG4876	unkown
NC3_16700	COG1959	2 iron, 2 sulfur cluster binding
NC3_16710	COG0702	epimerase
NC3_16730	COG0247	lactate metabolic process
NC3_16740	COG1139	Iron-sulfur cluster binding protein
NC3_16750	COG1556	Lactate utilization protein
NC3_16790	COG2323	membrane
NC3_16800	COG1309	transcriptional regulator
NC3_16810	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NC3_16810	COG2124	cytochrome p450
NC3_16820	COG3591	Belongs to the peptidase S1B family
NC3_16830	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NC3_16840	COG3209	COG3209 Rhs family protein
NC3_16850	COG1366	Belongs to the anti-sigma-factor antagonist family
NC3_16880	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NC3_16890	COG1388	LysM domain
NC3_16900	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NC3_16910	COG4224	UPF0291 protein
NC3_16920	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NC3_16940	COG3763	UPF0154 protein
NC3_16960	COG0785	Cytochrome C biogenesis protein
NC3_16970	COG4846	Membrane protein involved in cytochrome C biogenesis
NC3_16990	COG0071	Belongs to the small heat shock protein (HSP20) family
NC3_17020	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NC3_17030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NC3_17070	COG0824	Thioesterase
NC3_17090	COG4841	protein insertion into membrane
NC3_17100	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NC3_17110	COG1832	CoA-binding protein
NC3_17120	COG0187	DNA topoisomerase II activity
NC3_17130	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NC3_17160	COG0738	Major facilitator superfamily
NC3_17170	COG0473	3-isopropylmalate dehydrogenase activity
NC3_17180	COG0110	maltose O-acetyltransferase activity
NC3_17190	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NC3_17200	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NC3_17210	COG0640	Transcriptional regulator
NC3_17250	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NC3_17260	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NC3_17280	COG1309	transcriptional regulator
NC3_17290	COG2249	NAD(P)H dehydrogenase (quinone) activity
NC3_17300	COG1733	regulation of RNA biosynthetic process
NC3_17320	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NC3_17330	COG0251	oxidation-reduction process
NC3_17400	COG0657	acetylesterase activity
NC3_17420	COG2723	6-phospho-beta-galactosidase activity
NC3_17430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NC3_17430	COG2190	(PTS) system
NC3_17430	COG1263	PTS System
NC3_17460	COG2205	protein histidine kinase activity
NC3_17470	COG0745	RESPONSE REGULATOR receiver
NC3_17490	COG3507	Belongs to the glycosyl hydrolase 43 family
NC3_17500	COG1012	belongs to the aldehyde dehydrogenase family
NC3_17510	COG1486	melibiose metabolic process
NC3_17520	COG0395	ABC-type sugar transport system, permease component
NC3_17530	COG1175	transmembrane transport
NC3_17540	COG1653	transport
NC3_17550	COG1609	Transcriptional regulator
NC3_17560	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NC3_17590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NC3_17610	COG0456	acetyltransferase
NC3_17620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NC3_17650	COG5444	nuclease activity
NC3_17670	COG1846	Transcriptional regulator
NC3_17680	COG2814	Major facilitator Superfamily
NC3_17700	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NC3_17700	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NC3_17700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NC3_17710	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NC3_17710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NC3_17710	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NC3_17720	COG1105	Belongs to the carbohydrate kinase PfkB family
NC3_17740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NC3_17780	COG1012	belongs to the aldehyde dehydrogenase family
NC3_17790	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NC3_17800	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NC3_17810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NC3_17820	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NC3_17830	COG1024	Enoyl-CoA hydratase
NC3_17840	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NC3_17850	COG0511	ligase activity, forming carbon-carbon bonds
NC3_17860	COG0439	Biotin carboxylase
NC3_17870	COG0318	PFAM AMP-dependent synthetase and ligase
NC3_17880	COG1960	acyl-CoA dehydrogenase activity
NC3_17890	COG1649	PFAM Uncharacterised BCR, COG1649
NC3_17900	COG2365	Tyrosine phosphatase family
NC3_17910	COG1349	DNA-binding transcription factor activity
NC3_17920	COG1942	4-Oxalocrotonate Tautomerase
NC3_17940	COG3835	regulator
NC3_17950	COG0277	FAD linked oxidase domain protein
NC3_17960	COG0247	lactate metabolic process
NC3_18000	COG0166	Belongs to the GPI family
NC3_18010	COG2246	polysaccharide biosynthetic process
NC3_18020	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NC3_18030	COG0586	Pfam SNARE associated Golgi protein
NC3_18040	COG1587	Uroporphyrinogen-III synthase
NC3_18060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NC3_18100	COG0534	Mate efflux family protein
NC3_18110	COG2027	D-alanyl-D-alanine carboxypeptidase
NC3_18120	COG4677	pectinesterase activity
NC3_18130	COG2323	membrane
NC3_18140	COG2146	nitrite reductase [NAD(P)H] activity
NC3_18150	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NC3_18160	COG0243	molybdopterin cofactor binding
NC3_18170	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NC3_18180	COG2223	nitrite transmembrane transporter activity
NC3_18190	COG0493	'glutamate synthase
NC3_18200	COG0070	glutamate synthase
NC3_18200	COG0067	glutamate synthase
NC3_18200	COG0069	glutamate synthase activity
NC3_18210	COG0583	DNA-binding transcription factor activity
NC3_18230	COG1132	(ABC) transporter
NC3_18240	COG0789	Transcriptional regulator
NC3_18240	COG4978	Transcriptional regulator
NC3_18250	COG0454	-acetyltransferase
NC3_18260	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NC3_18270	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NC3_18280	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NC3_18300	COG0243	molybdopterin cofactor binding
NC3_18320	COG1070	Carbohydrate kinase
NC3_18330	COG2115	Belongs to the xylose isomerase family
NC3_18340	COG1940	carbohydrate kinase activity
NC3_18360	COG2211	Major facilitator Superfamily
NC3_18370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NC3_18380	COG1994	Peptidase M50
NC3_18420	COG1309	transcriptional regulator
NC3_18430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NC3_18440	COG3708	Transcriptional regulator
NC3_18450	COG2378	regulation of single-species biofilm formation
NC3_18470	COG0640	Transcriptional regulator
NC3_18480	COG0531	amino acid
NC3_18490	COG0741	lytic transglycosylase activity
NC3_18500	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NC3_18510	COG2079	MmgE PrpD family protein
NC3_18520	COG0372	Belongs to the citrate synthase family
NC3_18530	COG2322	membrane
NC3_18550	COG3584	3D domain protein
NC3_18550	COG1388	LysM domain
NC3_18560	COG0514	ATP-dependent DNA helicase (RecQ)
NC3_18580	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NC3_18630	COG1012	belongs to the aldehyde dehydrogenase family
NC3_18640	COG1657	PFAM Prenyltransferase squalene oxidase
NC3_18650	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NC3_18660	COG0385	Bile acid
NC3_18670	COG0508	dehydrogenase complex catalyzes the overall conversion of
NC3_18680	COG0567	Dehydrogenase, E1 component
NC3_18690	COG4548	von Willebrand factor, type A
NC3_18700	COG0714	Associated with various cellular activities
NC3_18710	COG2032	superoxide dismutase activity
NC3_18720	COG1388	LysM domain
NC3_18720	COG0791	NLP P60 protein
NC3_18730	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NC3_18750	COG0534	Mate efflux family protein
NC3_18760	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NC3_18770	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NC3_18790	COG2962	Rard protein
NC3_18820	COG1733	regulation of RNA biosynthetic process
NC3_18830	COG0778	Nitroreductase
NC3_18850	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NC3_18860	COG0793	Belongs to the peptidase S41A family
NC3_18860	COG3409	Peptidoglycan-binding domain 1 protein
NC3_18870	COG2226	methyltransferase
NC3_18890	COG1876	peptidase activity
NC3_18900	COG0813	purine-nucleoside phosphorylase activity
NC3_18920	COG0671	phosphoesterase, PA-phosphatase related
NC3_18960	COG4479	Belongs to the UPF0346 family
NC3_18980	COG1509	lysine 2,3-aminomutase activity
NC3_18990	COG3829	transcription factor binding
NC3_19000	COG0463	Glycosyl transferase, family 2
NC3_19030	COG4641	Protein conserved in bacteria
NC3_19050	COG1086	Polysaccharide biosynthesis protein
NC3_19060	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NC3_19070	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NC3_19080	COG1846	Transcriptional regulator
NC3_19120	COG4698	Protein conserved in bacteria
NC3_19130	COG2755	lipolytic protein G-D-S-L family
NC3_19140	COG1999	signal sequence binding
NC3_19170	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NC3_19180	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NC3_19190	COG1272	protein, Hemolysin III
NC3_19200	COG0204	Acyl-transferase
NC3_19210	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NC3_19220	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NC3_19230	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NC3_19250	COG2136	Putative SAM-dependent methyltransferase
NC3_19250	COG2521	methyltransferase
NC3_19270	COG0129	dihydroxy-acid dehydratase activity
NC3_19280	COG1413	lyase activity
NC3_19290	COG1418	mRNA catabolic process
NC3_19300	COG0386	Belongs to the glutathione peroxidase family
NC3_19310	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NC3_19320	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NC3_19330	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NC3_19350	COG1278	Cold shock
NC3_19380	COG0328	RNA-DNA hybrid ribonuclease activity
NC3_19390	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NC3_19400	COG0328	RNA-DNA hybrid ribonuclease activity
NC3_19410	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NC3_19440	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NC3_19450	COG1755	Isoprenylcysteine carboxyl methyltransferase
NC3_19460	COG3424	synthase
NC3_19470	COG0456	acetyltransferase
NC3_19470	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NC3_19490	COG0726	polysaccharide deacetylase
NC3_19500	COG2233	PERMEase
NC3_19510	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NC3_19520	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NC3_19530	COG1199	ATP-dependent helicase activity
NC3_19550	COG0116	Belongs to the methyltransferase superfamily
NC3_19560	COG3599	regulation of cell shape
NC3_19570	COG4474	Belongs to the UPF0398 family
NC3_19580	COG3359	exonuclease
NC3_19590	COG1111	helicase
NC3_19590	COG1205	dead DEAH box helicase
NC3_19600	COG1902	pentaerythritol trinitrate reductase activity
NC3_19610	COG2190	(PTS) system
NC3_19620	COG0071	Belongs to the small heat shock protein (HSP20) family
NC3_19670	COG3331	DNA recombination
NC3_19680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NC3_19680	COG4499	WXG100 protein secretion system (Wss), protein YukC
NC3_19700	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NC3_19710	COG3935	DnaD domain protein
NC3_19720	COG0017	Asparaginyl-tRNA synthetase
NC3_19730	COG5353	protein conserved in bacteria
NC3_19750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NC3_19750	COG1199	ATP-dependent helicase activity
NC3_19760	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NC3_19770	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NC3_19780	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NC3_19800	COG0617	tRNA 3'-terminal CCA addition
NC3_19810	COG0438	transferase activity, transferring glycosyl groups
NC3_19820	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NC3_19830	COG1803	Methylglyoxal synthase
NC3_19840	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NC3_19850	COG1694	Mazg nucleotide pyrophosphohydrolase
NC3_19860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NC3_19880	COG4347	Protein of unknown function (DUF1405)
NC3_19890	COG2010	Cytochrome c
NC3_19890	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NC3_19900	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NC3_19910	COG0723	plastoquinol--plastocyanin reductase activity
NC3_19930	COG5582	Belongs to the UPF0302 family
NC3_19940	COG0457	Tetratricopeptide repeat
NC3_19950	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NC3_19960	COG0287	Prephenate dehydrogenase
NC3_19970	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NC3_19980	COG0159	tryptophan synthase activity
NC3_19990	COG0133	tryptophan synthase activity
NC3_20000	COG0135	phosphoribosylanthranilate isomerase activity
NC3_20010	COG0134	indole-3-glycerol-phosphate synthase activity
NC3_20020	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NC3_20040	COG4401	Chorismate mutase type I
NC3_20050	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NC3_20060	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NC3_20070	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NC3_20080	COG0105	UTP biosynthetic process
NC3_20090	COG0142	geranyltranstransferase activity
NC3_20100	COG2226	methyltransferase
NC3_20110	COG0142	geranyltranstransferase activity
NC3_20130	COG0302	gtp cyclohydrolase
NC3_20140	COG0776	regulation of translation
NC3_20150	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NC3_20180	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NC3_20190	COG1160	GTP binding
NC3_20240	COG1304	FMN binding
NC3_20250	COG0539	negative regulation of cytoplasmic translation
NC3_20260	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NC3_20280	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
NC3_20290	COG2959	enzyme of heme biosynthesis
NC3_20300	COG3773	Cell wall hydrolase
NC3_20300	COG3409	Peptidoglycan-binding domain 1 protein
NC3_20310	COG2339	peptidase activity
NC3_20320	COG0492	ferredoxin-NADP+ reductase activity
NC3_20330	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NC3_20340	COG4862	establishment of competence for transformation
NC3_20350	COG1408	metallophosphoesterase
NC3_20370	COG1388	LysM domain
NC3_20380	COG1266	CAAX protease self-immunity
NC3_20390	COG0514	ATP-dependent DNA helicase (RecQ)
NC3_20400	COG4955	Helix-turn-helix domain
NC3_20410	COG1141	Ferredoxin
NC3_20420	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NC3_20430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NC3_20460	COG1595	DNA-templated transcription, initiation
NC3_20470	COG5002	protein histidine kinase activity
NC3_20480	COG0745	RESPONSE REGULATOR receiver
NC3_20490	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NC3_20500	COG1333	cytochrome c biogenesis protein
NC3_20510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NC3_20520	COG1187	pseudouridine synthase activity
NC3_20530	COG0700	Nucleoside recognition
NC3_20540	COG2715	membrane protein required for spore maturation
NC3_20550	COG1686	Belongs to the peptidase S11 family
NC3_20570	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NC3_20580	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NC3_20600	COG1547	Domain of unknown function (DUF309)
NC3_20610	COG0456	acetyltransferase
NC3_20620	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NC3_20630	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NC3_20630	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NC3_20640	COG0307	riboflavin synthase, alpha
NC3_20680	COG2814	Major facilitator Superfamily
NC3_20690	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NC3_20700	COG4086	secreted protein
NC3_20710	COG0019	diaminopimelate decarboxylase activity
NC3_20720	COG0697	spore germination
NC3_20750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NC3_20790	COG1191	sigma factor activity
NC3_20800	COG2172	sigma factor antagonist activity
NC3_20820	COG1686	Belongs to the peptidase S11 family
NC3_20830	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NC3_20840	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NC3_20850	COG4974	Belongs to the 'phage' integrase family
NC3_20870	COG0735	belongs to the Fur family
NC3_20880	COG1300	Membrane
NC3_20890	COG1404	Belongs to the peptidase S8 family
NC3_20910	COG2153	protein acetylation
NC3_20920	COG1379	DNA repair
NC3_20930	COG0494	nUDIX hydrolase
NC3_20940	COG0667	Aldo Keto reductase
NC3_20960	COG1073	alpha beta
NC3_20970	COG0457	Tetratricopeptide repeat
NC3_20990	COG4918	Iron-sulphur cluster biosynthesis
NC3_21000	COG4305	rare lipoprotein A
NC3_21010	COG0456	acetyltransferase
NC3_21010	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NC3_21020	COG0456	acetyltransferase
NC3_21040	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NC3_21060	COG2211	Major facilitator Superfamily
NC3_21070	COG1072	(Pantothenic acid kinase))
NC3_21080	COG0446	pyridine nucleotide-disulphide oxidoreductase
NC3_21100	COG0300	oxidoreductase activity
NC3_21110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NC3_21120	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NC3_21140	COG4187	Peptidase family M20/M25/M40
NC3_21150	COG1902	pentaerythritol trinitrate reductase activity
NC3_21160	COG0596	Alpha beta hydrolase
NC3_21170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NC3_21190	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NC3_21200	COG2188	Transcriptional regulator
NC3_21210	COG2723	6-phospho-beta-galactosidase activity
NC3_21220	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NC3_21230	COG1447	Phosphotransferase system cellobiose-specific component IIA
NC3_21240	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NC3_21260	COG1028	Short-chain dehydrogenase reductase Sdr
NC3_21280	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NC3_21290	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NC3_21310	COG0706	membrane insertase activity
NC3_21320	COG0835	chemotaxis
NC3_21330	COG2195	Cleaves the N-terminal amino acid of tripeptides
NC3_21340	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NC3_21350	COG0346	lactoylglutathione lyase activity
NC3_21360	COG1376	ErfK ybiS ycfS ynhG family protein
NC3_21370	COG4129	membrane
NC3_21380	COG1126	abc transporter atp-binding protein
NC3_21390	COG0765	amino acid transport
NC3_21400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NC3_21420	COG1597	lipid kinase activity
NC3_21440	COG0508	dehydrogenase complex catalyzes the overall conversion of
NC3_21450	COG0022	dehydrogenase e1 component
NC3_21460	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NC3_21470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NC3_21480	COG3426	butyrate kinase activity
NC3_21490	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NC3_21500	COG0280	phosphate acetyltransferase
NC3_21510	COG3290	protein histidine kinase activity
NC3_21510	COG3829	transcription factor binding
NC3_21530	COG0584	glycerophosphoryl diester phosphodiesterase
NC3_21540	COG0457	Tetratricopeptide repeat
NC3_21550	COG0745	RESPONSE REGULATOR receiver
NC3_21560	COG0750	zinc metalloprotease
NC3_21570	COG0497	DNA recombination
NC3_21580	COG1438	arginine binding
NC3_21590	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
NC3_21600	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NC3_21610	COG0142	geranyltranstransferase activity
NC3_21620	COG1722	exodeoxyribonuclease VII activity
NC3_21630	COG1570	exodeoxyribonuclease VII activity
NC3_21640	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NC3_21650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NC3_21660	COG1302	Protein conserved in bacteria
NC3_21670	COG0439	Biotin carboxylase
NC3_21680	COG0511	ligase activity, forming carbon-carbon bonds
NC3_21760	COG3854	ATPases associated with a variety of cellular activities
NC3_21780	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NC3_21790	COG0006	proline dipeptidase activity
NC3_21800	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NC3_21820	COG3872	metal-dependent enzyme
NC3_21840	COG1752	Esterase of the alpha-beta hydrolase superfamily
NC3_21850	COG1321	iron dependent repressor
NC3_21860	COG0095	Lipoate-protein ligase
NC3_21870	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NC3_21880	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NC3_21890	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NC3_21900	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NC3_21910	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NC3_21960	COG0681	Belongs to the peptidase S26 family
NC3_22030	COG4970	Tfp pilus assembly protein FimT
NC3_22040	COG4537	Required for transformation and DNA binding
NC3_22050	COG1459	type II secretion system
NC3_22060	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NC3_22070	COG1366	Belongs to the anti-sigma-factor antagonist family
NC3_22080	COG1393	Belongs to the ArsC family
NC3_22100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NC3_22120	COG0011	TIGRFAM Protein of
NC3_22130	COG2814	Major facilitator Superfamily
NC3_22140	COG2866	Carboxypeptidase
NC3_22150	COG1368	sulfuric ester hydrolase activity
NC3_22160	COG1940	carbohydrate kinase activity
NC3_22170	COG4483	Protein conserved in bacteria
NC3_22180	COG0457	Tetratricopeptide repeat
NC3_22180	COG0705	Rhomboid family
NC3_22210	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NC3_22220	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NC3_22250	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NC3_22260	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NC3_22270	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NC3_22280	COG0581	inorganic phosphate transmembrane transporter activity
NC3_22290	COG0573	inorganic phosphate transmembrane transporter activity
NC3_22300	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NC3_22310	COG0768	penicillin binding
NC3_22320	COG0477	Major facilitator Superfamily
NC3_22330	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NC3_22340	COG2839	Protein conserved in bacteria
NC3_22350	COG5521	maltodextrose utilization protein MalA
NC3_22360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NC3_22370	COG1388	LysM domain
NC3_22380	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NC3_22390	COG4709	membrane
NC3_22400	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
NC3_22410	COG1940	carbohydrate kinase activity
NC3_22420	COG0735	belongs to the Fur family
NC3_22430	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NC3_22440	COG1121	(ABC) transporter
NC3_22450	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NC3_22480	COG0513	Belongs to the DEAD box helicase family
NC3_22500	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NC3_22510	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NC3_22520	COG2384	SAM-dependent methyltransferase
NC3_22530	COG2010	Cytochrome c
NC3_22540	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NC3_22550	COG0358	DNA primase activity
NC3_22560	COG1671	Belongs to the UPF0178 family
NC3_22570	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NC3_22580	COG0517	IMP dehydrogenase activity
NC3_22590	COG0751	glycine-tRNA ligase activity
NC3_22600	COG0752	glycyl-tRNA synthetase alpha subunit
NC3_22610	COG1381	Involved in DNA repair and RecF pathway recombination
NC3_22630	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NC3_22640	COG0295	cytidine deaminase activity
NC3_22650	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NC3_22660	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NC3_22670	COG1480	7TM receptor with intracellular HD hydrolase
NC3_22680	COG1702	phosphate starvation-inducible protein PhoH
NC3_22690	COG0561	phosphatase activity
NC3_22720	COG4864	UPF0365 protein
NC3_22730	COG1030	water channel activity
NC3_22740	COG1610	YqeY-like protein
NC3_22760	COG1283	sodium-dependent phosphate transmembrane transporter activity
NC3_22770	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NC3_22780	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NC3_22790	COG2264	protein methyltransferase activity
NC3_22800	COG0484	heat shock protein binding
NC3_22810	COG0443	Heat shock 70 kDa protein
NC3_22820	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NC3_22830	COG1420	regulation of RNA biosynthetic process
NC3_22840	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NC3_22850	COG0481	GTPase activity
NC3_22870	COG0860	N-Acetylmuramoyl-L-alanine amidase
NC3_22880	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NC3_22890	COG0268	Binds directly to 16S ribosomal RNA
NC3_22900	COG1466	dna polymerase III delta subunit
NC3_22920	COG0658	competence protein
NC3_22920	COG2333	competence protein COMEC
NC3_22930	COG2131	deaminase
NC3_22940	COG1555	photosystem II stabilization
NC3_22940	COG1596	polysaccharide export
NC3_22950	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NC3_22960	COG2226	methyltransferase
NC3_22970	COG0799	negative regulation of ribosome biogenesis
NC3_22980	COG1713	HD superfamily hydrolase involved in NAD metabolism
NC3_22990	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NC3_23000	COG1534	Rna-binding protein
NC3_23010	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NC3_23020	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NC3_23030	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
NC3_23050	COG2755	lipolytic protein G-D-S-L family
NC3_23070	COG0457	Tetratricopeptide repeat
NC3_23100	COG2186	Transcriptional regulator
NC3_23130	COG1028	Short-chain dehydrogenase reductase Sdr
NC3_23140	COG3958	Transketolase
NC3_23150	COG3959	Transketolase, thiamine diphosphate binding domain
NC3_23190	COG0726	polysaccharide deacetylase
NC3_23260	COG1131	(ABC) transporter
NC3_23310	COG2160	L-arabinose isomerase activity
NC3_23340	COG1609	Transcriptional regulator
NC3_23360	COG1846	Transcriptional regulator
NC3_23380	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NC3_23390	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
NC3_23400	COG1733	regulation of RNA biosynthetic process
NC3_23410	COG0657	acetylesterase activity
NC3_23460	COG3209	COG3209 Rhs family protein
NC3_23470	COG2602	Beta-lactamase
NC3_23480	COG1960	acyl-CoA dehydrogenase activity
NC3_23490	COG1126	abc transporter atp-binding protein
NC3_23500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NC3_23510	COG0765	amino acid transport
NC3_23530	COG3546	catalase activity
NC3_23540	COG1063	alcohol dehydrogenase
NC3_23560	COG1028	Short-chain dehydrogenase reductase Sdr
NC3_23580	COG1115	amino acid carrier protein
NC3_23590	COG0583	DNA-binding transcription factor activity
NC3_23600	COG0842	Transport permease protein
NC3_23610	COG1511	domain protein
NC3_23610	COG0842	Transport permease protein
NC3_23620	COG1131	(ABC) transporter
NC3_23630	COG1063	alcohol dehydrogenase
NC3_23640	COG2226	methyltransferase
NC3_23690	COG0626	cystathionine gamma-synthase activity
NC3_23700	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NC3_23710	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NC3_23720	COG2226	methyltransferase
NC3_23750	COG0768	penicillin binding
NC3_23760	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NC3_23770	COG0572	uridine kinase
NC3_23780	COG0826	peptidase U32
NC3_23790	COG0826	peptidase U32
NC3_23800	COG4122	O-methyltransferase activity
NC3_23810	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NC3_23820	COG0183	Belongs to the thiolase family
NC3_23830	COG0318	PFAM AMP-dependent synthetase and ligase
NC3_23840	COG1268	BioY protein
NC3_23860	COG3906	Belongs to the UPF0473 family
NC3_23870	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NC3_23880	COG4472	Bacterial protein of unknown function (DUF965)
NC3_23890	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NC3_23900	COG0628	permease
NC3_23910	COG1126	abc transporter atp-binding protein
NC3_23920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NC3_23930	COG0765	amino acid transport
NC3_23940	COG0765	amino acid transport
NC3_23970	COG3881	PFAM PRC-barrel domain
NC3_23980	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NC3_23990	COG0457	Tetratricopeptide repeat
NC3_24000	COG0482	sulfurtransferase activity
NC3_24010	COG1104	cysteine desulfurase activity
NC3_24020	COG1959	2 iron, 2 sulfur cluster binding
NC3_24030	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NC3_24040	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NC3_24060	COG0124	histidyl-tRNA synthetase
NC3_24080	COG0860	N-Acetylmuramoyl-L-alanine amidase
NC3_24080	COG4991	sh3 domain protein
NC3_24080	COG3103	Sh3 type 3 domain protein
NC3_24090	COG1490	D-aminoacyl-tRNA deacylase activity
NC3_24100	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NC3_24110	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NC3_24120	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NC3_24120	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NC3_24130	COG5416	Lipopolysaccharide assembly protein A domain
NC3_24140	COG0490	domain, Protein
NC3_24150	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NC3_24150	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NC3_24170	COG2244	polysaccharide biosynthetic process
NC3_24180	COG2323	membrane
NC3_24200	COG1862	Preprotein translocase
NC3_24210	COG0343	queuine tRNA-ribosyltransferase activity
NC3_24220	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NC3_24240	COG2255	four-way junction helicase activity
NC3_24250	COG0632	four-way junction helicase activity
NC3_24270	COG2112	serine threonine protein kinase
NC3_24300	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NC3_24330	COG1388	LysM domain
NC3_24340	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NC3_24350	COG0157	Belongs to the NadC ModD family
NC3_24360	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NC3_24370	COG1104	cysteine desulfurase activity
NC3_24380	COG1827	regulation of RNA biosynthetic process
NC3_24390	COG0077	Prephenate dehydratase
NC3_24400	COG4492	Belongs to the UPF0735 family
NC3_24410	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NC3_24420	COG3290	protein histidine kinase activity
NC3_24430	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NC3_24440	COG2868	ribosomal protein
NC3_24450	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NC3_24460	COG1994	Peptidase M50
NC3_24470	COG0739	heme binding
NC3_24480	COG2894	cell division
NC3_24490	COG0850	regulation of cytokinetic process
NC3_24500	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NC3_24520	COG1077	Cell shape determining protein MreB Mrl
NC3_24530	COG2003	Belongs to the UPF0758 family
NC3_24540	COG0424	maF-like protein
NC3_24560	COG0285	dihydrofolate synthase activity
NC3_24570	COG0525	valine-tRNA ligase activity
NC3_24590	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NC3_24600	COG1388	LysM domain
NC3_24610	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NC3_24620	COG0113	porphobilinogen synthase activity
NC3_24630	COG1587	Uroporphyrinogen-III synthase
NC3_24640	COG0181	hydroxymethylbilane synthase activity
NC3_24650	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NC3_24660	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NC3_24680	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NC3_24690	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NC3_24700	COG0470	DNA polymerase III
NC3_24700	COG1067	ATP-dependent peptidase activity
NC3_24710	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NC3_24720	COG0544	peptidyl-prolyl cis-trans isomerase activity
NC3_24730	COG0457	Tetratricopeptide repeat
NC3_24730	COG1477	protein flavinylation
NC3_24740	COG0066	3-isopropylmalate dehydratase activity
NC3_24750	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NC3_24760	COG0473	3-isopropylmalate dehydrogenase activity
NC3_24770	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NC3_24780	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NC3_24790	COG0440	acetolactate synthase activity
NC3_24800	COG0028	Belongs to the TPP enzyme family
NC3_24810	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NC3_24820	COG2706	6-phosphogluconolactonase activity
NC3_24830	COG3339	Conserved Protein
NC3_24840	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NC3_24850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NC3_24860	COG1696	Membrane protein involved in D-alanine export
NC3_24870	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NC3_24980	COG0582	viral genome integration into host DNA
NC3_24990	COG0622	Phosphoesterase
NC3_25000	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NC3_25010	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NC3_25020	COG5401	PFAM Sporulation and spore germination
NC3_25030	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NC3_25040	COG1846	Transcriptional regulator
NC3_25050	COG2197	response regulator
NC3_25060	COG2851	Citrate transporter
NC3_25070	COG0583	DNA-binding transcription factor activity
NC3_25080	COG2828	Protein conserved in bacteria
NC3_25100	COG0824	Thioesterase
NC3_25110	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NC3_25120	COG1053	succinate dehydrogenase
NC3_25130	COG2009	succinate dehydrogenase
NC3_25140	COG1719	4-vinyl reductase, 4VR
NC3_25150	COG0527	aspartate kinase activity
NC3_25160	COG0322	excinuclease ABC activity
NC3_25170	COG3118	belongs to the thioredoxin family
NC3_25180	COG3534	alpha-L-arabinofuranosidase
NC3_25190	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NC3_25200	COG2086	electron transfer activity
NC3_25210	COG1024	Enoyl-CoA hydratase
NC3_25220	COG1309	transcriptional regulator
NC3_25230	COG0318	PFAM AMP-dependent synthetase and ligase
NC3_25250	COG3766	membrane
NC3_25260	COG1193	negative regulation of DNA recombination
NC3_25270	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NC3_25270	COG1796	DNA polymerase
NC3_25280	COG1286	toxin biosynthetic process
NC3_25290	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NC3_25300	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NC3_25310	COG0072	phenylalanine-tRNA ligase activity
NC3_25310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NC3_25320	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NC3_25330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NC3_25350	COG1966	Carbon starvation protein
NC3_25360	COG1363	Peptidase, m42
NC3_25380	COG3326	Membrane
NC3_25390	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NC3_25400	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NC3_25410	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NC3_25430	COG1011	Hydrolase
NC3_25450	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NC3_25470	COG0398	Pfam SNARE associated Golgi protein
NC3_25480	COG1484	DNA-dependent DNA replication
NC3_25490	COG3611	Membrane attachment protein
NC3_25500	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NC3_25520	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NC3_25530	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NC3_25540	COG0237	dephospho-CoA kinase activity
NC3_25550	COG1971	Probably functions as a manganese efflux pump
NC3_25560	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NC3_25570	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NC3_25570	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NC3_25580	COG5002	protein histidine kinase activity
NC3_25590	COG0745	RESPONSE REGULATOR receiver
NC3_25600	COG0039	L-malate dehydrogenase activity
NC3_25610	COG0538	isocitrate dehydrogenase activity
NC3_25620	COG0372	Belongs to the citrate synthase family
NC3_25630	COG2707	UPF0756 membrane protein
NC3_25640	COG0628	permease
NC3_25650	COG3030	protein affecting phage T7 exclusion by the F plasmid
NC3_25670	COG0205	6-phosphofructokinase activity
NC3_25680	COG0825	malonyl-CoA metabolic process
NC3_25690	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NC3_25700	COG0281	malic enzyme
NC3_25710	COG0587	DNA-directed DNA polymerase activity
NC3_25750	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NC3_25770	COG4109	DRTGG domain
NC3_25780	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NC3_25790	COG1028	Short-chain dehydrogenase reductase Sdr
NC3_25810	COG0165	Argininosuccinate lyase
NC3_25820	COG0137	argininosuccinate synthase activity
NC3_25830	COG0521	Mo-molybdopterin cofactor biosynthetic process
NC3_25840	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NC3_25850	COG0827	DNA restriction-modification system
NC3_25860	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NC3_25870	COG3874	Sporulation protein YtfJ
NC3_25890	COG1714	RDD family
NC3_25900	COG0616	signal peptide processing
NC3_25910	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NC3_25930	COG3239	Fatty acid desaturase
NC3_25940	COG4585	Histidine kinase
NC3_25950	COG2197	response regulator
NC3_25960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NC3_25970	COG0745	RESPONSE REGULATOR receiver
NC3_25980	COG2205	protein histidine kinase activity
NC3_25990	COG0772	Belongs to the SEDS family
NC3_26000	COG1695	Transcriptional regulator
NC3_26010	COG1136	(ABC) transporter
NC3_26020	COG0577	efflux transmembrane transporter activity
NC3_26030	COG0402	S-adenosylhomocysteine deaminase activity
NC3_26040	COG2249	NAD(P)H dehydrogenase (quinone) activity
NC3_26070	COG1279	arginine transmembrane transporter activity
NC3_26080	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NC3_26100	COG0301	tRNA thio-modification
NC3_26110	COG1104	cysteine desulfurase activity
NC3_26120	COG1114	Component of the transport system for branched-chain amino acids
NC3_26130	COG1114	Component of the transport system for branched-chain amino acids
NC3_26140	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NC3_26150	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NC3_26160	COG1309	transcriptional regulator
NC3_26170	COG1956	GAF domain-containing protein
NC3_26180	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NC3_26190	COG1335	isochorismatase
NC3_26210	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NC3_26220	COG2329	Antibiotic biosynthesis monooxygenase
NC3_26230	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NC3_26240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NC3_26250	COG0454	-acetyltransferase
NC3_26260	COG0517	IMP dehydrogenase activity
NC3_26270	COG0123	including yeast histone deacetylase and acetoin utilization protein
NC3_26280	COG1609	Transcriptional regulator
NC3_26290	COG1605	Chorismate mutase
NC3_26290	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NC3_26300	COG3118	belongs to the thioredoxin family
NC3_26310	COG4980	gas vesicle protein
NC3_26320	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NC3_26330	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NC3_26340	COG1674	ftsk spoiiie
NC3_26350	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NC3_26360	COG4848	Belongs to the UPF0354 family
NC3_26370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NC3_26400	COG1363	Peptidase, m42
NC3_26410	COG5584	Small secreted protein
NC3_26420	COG0281	malic enzyme
NC3_26430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NC3_26440	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NC3_26460	COG0510	thiamine kinase activity
NC3_26470	COG1597	lipid kinase activity
NC3_26490	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NC3_26500	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NC3_26510	COG3340	Belongs to the peptidase S51 family
NC3_26520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NC3_26530	COG2252	PERMEase
NC3_26540	COG1349	DNA-binding transcription factor activity
NC3_26550	COG1187	pseudouridine synthase activity
NC3_26560	COG2244	polysaccharide biosynthetic process
NC3_26570	COG2081	HI0933 family
NC3_26590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NC3_26600	COG3196	Protein conserved in bacteria
NC3_26620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NC3_26630	COG5578	integral membrane protein
NC3_26640	COG0673	inositol 2-dehydrogenase activity
NC3_26650	COG1653	transport
NC3_26660	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NC3_26670	COG4209	transmembrane transport
NC3_26680	COG2207	Transcriptional regulator
NC3_26690	COG1733	regulation of RNA biosynthetic process
NC3_26700	COG2814	Major facilitator Superfamily
NC3_26710	COG0656	L-ascorbic acid biosynthetic process
NC3_26720	COG1653	transport
NC3_26730	COG0395	ABC-type sugar transport system, permease component
NC3_26740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NC3_26750	COG1073	alpha beta
NC3_26760	COG0495	leucyl-tRNA aminoacylation
NC3_26780	COG1366	Belongs to the anti-sigma-factor antagonist family
NC3_26780	COG2202	Pas domain
NC3_26790	COG2433	Pfam Transposase IS66
NC3_26800	COG0577	efflux transmembrane transporter activity
NC3_26810	COG1136	(ABC) transporter
NC3_26830	COG1131	(ABC) transporter
NC3_26840	COG1725	Transcriptional regulator
NC3_26880	COG1242	4 iron, 4 sulfur cluster binding
NC3_26890	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NC3_26900	COG4326	sporulation control protein
NC3_26920	COG2267	carboxylic ester hydrolase activity
NC3_26930	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NC3_26940	COG0367	asparagine synthase
NC3_26950	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NC3_26960	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NC3_26980	COG1506	peptidase
NC3_26990	COG1233	COG1233 Phytoene dehydrogenase and related
NC3_27030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NC3_27040	COG1116	anion transmembrane transporter activity
NC3_27050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NC3_27060	COG0494	nUDIX hydrolase
NC3_27070	COG2310	stress, protein
NC3_27100	COG4824	toxin secretion phage lysis holin
NC3_27120	COG0783	Belongs to the Dps family
NC3_27150	COG1854	S-ribosylhomocysteine lyase activity
NC3_27160	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NC3_27170	COG0288	reversible hydration of carbon dioxide
NC3_27180	COG0803	Belongs to the bacterial solute-binding protein 9 family
NC3_27180	COG3443	Belongs to the bacterial solute-binding protein 9 family
NC3_27200	COG1271	oxidase subunit
NC3_27210	COG1294	oxidase, subunit
NC3_27240	COG4948	Mandelate Racemase Muconate Lactonizing
NC3_27250	COG0318	PFAM AMP-dependent synthetase and ligase
NC3_27260	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NC3_27270	COG0596	Alpha beta hydrolase
NC3_27280	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NC3_27290	COG1169	isochorismate synthase
NC3_27300	COG1575	Belongs to the MenA family. Type 1 subfamily
NC3_27310	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NC3_27330	COG3859	Proton-coupled thiamine transporter YuaJ
NC3_27350	COG1247	-acetyltransferase
NC3_27360	COG3339	Conserved Protein
NC3_27370	COG0772	Belongs to the SEDS family
NC3_27380	COG0772	Belongs to the SEDS family
NC3_27390	COG2268	Band 7 protein
NC3_27400	COG1585	Membrane protein implicated in regulation of membrane protease activity
NC3_27410	COG2318	DinB family
NC3_27420	COG1454	alcohol dehydrogenase
NC3_27430	COG1012	belongs to the aldehyde dehydrogenase family
NC3_27440	COG1510	regulation of RNA biosynthetic process
NC3_27460	COG3409	Peptidoglycan-binding domain 1 protein
NC3_27460	COG5632	N-Acetylmuramoyl-L-alanine amidase
NC3_27530	COG3778	Protein conserved in bacteria
NC3_27540	COG3299	homolog of phage Mu protein gp47
NC3_27550	COG3628	GPW Gp25 family protein
NC3_27570	COG4193	domain, Protein
NC3_27580	COG1652	LysM domain
NC3_27590	COG3953	SLT domain
NC3_27590	COG5280	Phage tail tape measure protein TP901
NC3_27690	COG4653	Phage capsid family
NC3_27700	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NC3_27710	COG5518	Phage portal protein
NC3_27720	COG1783	phage Terminase large subunit
NC3_27730	COG5484	DNA packaging
NC3_27740	COG1595	DNA-templated transcription, initiation
NC3_27760	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
NC3_27800	COG1396	sequence-specific DNA binding
NC3_27830	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NC3_27860	COG0628	permease
NC3_27880	COG0673	inositol 2-dehydrogenase activity
NC3_27890	COG0693	protein deglycase activity
NC3_27900	COG0840	transmembrane signaling receptor activity
NC3_27910	COG0840	transmembrane signaling receptor activity
NC3_27920	COG0840	transmembrane signaling receptor activity
NC3_27930	COG0840	transmembrane signaling receptor activity
NC3_27960	COG2070	2-Nitropropane dioxygenase
NC3_27970	COG0432	Pfam Uncharacterised protein family UPF0047
NC3_27980	COG1253	flavin adenine dinucleotide binding
NC3_27990	COG2738	Putative neutral zinc metallopeptidase
NC3_28010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NC3_28040	COG0166	Belongs to the GPI family
NC3_28050	COG1979	alcohol dehydrogenase
NC3_28060	COG1979	alcohol dehydrogenase
NC3_28070	COG2155	Conserved Protein
NC3_28080	COG1098	S1 RNA binding domain
NC3_28090	COG0436	Aminotransferase
NC3_28100	COG1522	sequence-specific DNA binding
NC3_28110	COG2267	carboxylic ester hydrolase activity
NC3_28130	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NC3_28140	COG2205	protein histidine kinase activity
NC3_28170	COG5018	Exonuclease
NC3_28180	COG2814	Major facilitator Superfamily
NC3_28190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NC3_28200	COG3011	Protein conserved in bacteria
NC3_28220	COG3290	protein histidine kinase activity
NC3_28230	COG4565	transcriptional regulatory protein
NC3_28240	COG1744	ABC transporter substrate-binding protein PnrA-like
NC3_28250	COG3845	ABC transporter
NC3_28260	COG4603	Belongs to the binding-protein-dependent transport system permease family
NC3_28270	COG1079	Belongs to the binding-protein-dependent transport system permease family
NC3_28280	COG3493	citrate carrier protein
NC3_28300	COG2111	Na H antiporter
NC3_28300	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NC3_28310	COG2111	Na H antiporter
NC3_28320	COG1006	Multisubunit Na H antiporter MnhC subunit
NC3_28330	COG0651	ATP synthesis coupled electron transport
NC3_28340	COG1863	multisubunit Na H antiporter MnhE subunit
NC3_28350	COG2212	antiporter activity
NC3_28360	COG1320	monovalent cation:proton antiporter activity
NC3_28370	COG2050	protein possibly involved in aromatic compounds catabolism
NC3_28380	COG2197	response regulator
NC3_28390	COG4585	Histidine kinase
NC3_28410	COG0142	geranyltranstransferase activity
NC3_28440	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
NC3_28450	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NC3_28460	COG1335	isochorismatase
NC3_28470	COG5506	Protein of unknown function (DUF1694)
NC3_28510	COG0628	permease
NC3_28540	COG1418	mRNA catabolic process
NC3_28550	COG1028	Short-chain dehydrogenase reductase Sdr
NC3_28570	COG1511	domain protein
NC3_28580	COG0433	COG0433 Predicted ATPase
NC3_28580	COG1674	ftsk spoiiie
NC3_28590	COG4499	WXG100 protein secretion system (Wss), protein YukC
NC3_28600	COG5417	Belongs to the EsaB family
NC3_28610	COG4842	Belongs to the WXG100 family
NC3_28620	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NC3_28620	COG2508	Transcriptional regulator
NC3_28630	COG0686	Belongs to the AlaDH PNT family
NC3_28640	COG1268	BioY protein
NC3_28650	COG2056	Na+-H+ antiporter family
NC3_28660	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NC3_28670	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
NC3_28680	COG3584	3D domain protein
NC3_28710	COG1252	NADH dehydrogenase
NC3_28720	COG0492	ferredoxin-NADP+ reductase activity
NC3_28750	COG0316	Belongs to the HesB IscA family
NC3_28760	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NC3_28770	COG4844	belongs to the
NC3_28780	COG1252	NADH dehydrogenase
NC3_28800	COG4837	Protein of unknown function (DUF1462)
NC3_28810	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NC3_28820	COG0823	Involved in the tonB-independent uptake of proteins
NC3_28820	COG1506	peptidase
NC3_28820	COG4946	Tricorn protease homolog
NC3_28830	COG0083	homoserine kinase activity
NC3_28840	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NC3_28850	COG0460	homoserine dehydrogenase
NC3_28860	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NC3_28870	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NC3_28880	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NC3_28890	COG0647	UMP catabolic process
NC3_28900	COG2445	Protein of unknown function DUF86
NC3_28910	COG4470	Protein conserved in bacteria
NC3_28930	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NC3_28940	COG0739	heme binding
NC3_28980	COG3377	Domain of unknown function (DUF1805)
NC3_28990	COG0737	Belongs to the 5'-nucleotidase family
NC3_29000	COG1801	Protein of unknown function DUF72
NC3_29010	COG2508	Transcriptional regulator
NC3_29020	COG2140	Oxalate decarboxylase
NC3_29030	COG2814	Major facilitator Superfamily
NC3_29040	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NC3_29050	COG2356	endonuclease I
NC3_29070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NC3_29080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NC3_29090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NC3_29120	COG0561	phosphatase activity
NC3_29140	COG0642	Histidine kinase
NC3_29140	COG5002	protein histidine kinase activity
NC3_29150	COG0745	RESPONSE REGULATOR receiver
NC3_29160	COG2311	Membrane
NC3_29180	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NC3_29200	COG1309	transcriptional regulator
NC3_29240	COG0719	Fe-S assembly protein
NC3_29250	COG0822	iron-sulfur transferase activity
NC3_29260	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NC3_29270	COG0719	Fe-S assembly protein
NC3_29280	COG0396	ATPase activity
NC3_29300	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NC3_29310	COG1464	Belongs to the NlpA lipoprotein family
NC3_29320	COG2011	ABC-type metal ion transport system permease component
NC3_29330	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NC3_29350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NC3_29360	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NC3_29380	COG0509	glycine decarboxylation via glycine cleavage system
NC3_29390	COG1393	Belongs to the ArsC family
NC3_29400	COG1960	acyl-CoA dehydrogenase activity
NC3_29410	COG0183	Belongs to the thiolase family
NC3_29420	COG1024	Enoyl-CoA hydratase
NC3_29420	COG1250	3-hydroxyacyl-CoA dehydrogenase
NC3_29450	COG5577	PFAM Coat F domain
NC3_29470	COG1120	ATPase activity
NC3_29490	COG1028	Short-chain dehydrogenase reductase Sdr
NC3_29500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NC3_29510	COG0745	RESPONSE REGULATOR receiver
NC3_29520	COG2205	protein histidine kinase activity
NC3_29520	COG2770	Histidine kinase
NC3_29540	COG1309	transcriptional regulator
NC3_29550	COG0114	fumarate hydratase activity
NC3_29570	COG0697	spore germination
NC3_29580	COG0814	amino acid
NC3_29610	COG2197	response regulator
NC3_29620	COG4585	Histidine kinase
NC3_29630	COG4758	membrane
NC3_29650	COG1842	Phage shock protein A
NC3_29660	COG4758	membrane
NC3_29670	COG2096	Adenosyltransferase
NC3_29680	COG1028	Short-chain dehydrogenase reductase Sdr
NC3_29690	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NC3_29710	COG3604	Transcriptional regulator
NC3_29740	COG1454	alcohol dehydrogenase
NC3_29750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NC3_29760	COG1120	ATPase activity
NC3_29770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NC3_29780	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NC3_29800	COG2721	sulfolactate sulfo-lyase activity
NC3_29810	COG0246	Mannitol dehydrogenase
NC3_29820	COG1609	Transcriptional regulator
NC3_29830	COG1904	glucuronate isomerase
NC3_29840	COG2205	protein histidine kinase activity
NC3_29850	COG0745	RESPONSE REGULATOR receiver
NC3_29860	COG1120	ATPase activity
NC3_29870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NC3_29880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NC3_29890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NC3_29900	COG0531	amino acid
NC3_29930	COG1988	membrane-bound metal-dependent
NC3_29940	COG1368	sulfuric ester hydrolase activity
NC3_29950	COG0725	ABC transporter, periplasmic molybdate-binding protein
NC3_29960	COG4149	molybdate abc transporter
NC3_29970	COG0656	L-ascorbic acid biosynthetic process
NC3_29980	COG1940	carbohydrate kinase activity
NC3_29990	COG0025	NhaP-type Na H and K H
NC3_30000	COG2860	membrane
NC3_30010	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NC3_30020	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NC3_30030	COG2217	Heavy metal translocating P-type atpase
NC3_30040	COG1121	(ABC) transporter
NC3_30050	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NC3_30060	COG0803	Belongs to the bacterial solute-binding protein 9 family
NC3_30080	COG3226	Transcriptional regulator
NC3_30090	COG0784	Response regulator, receiver
NC3_30100	COG4191	Histidine kinase
NC3_30110	COG1027	Aspartate ammonia-lyase
NC3_30140	COG2217	Heavy metal translocating P-type atpase
NC3_30150	COG2608	mercury ion transmembrane transporter activity
NC3_30160	COG1937	Protein conserved in bacteria
NC3_30210	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NC3_30210	COG0463	Glycosyl transferase, family 2
NC3_30220	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NC3_30230	COG0557	exoribonuclease II activity
NC3_30240	COG1647	Serine aminopeptidase, S33
NC3_30250	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NC3_30260	COG2002	toxin-antitoxin pair type II binding
NC3_30270	COG1476	TRANSCRIPTIONal
NC3_30280	COG1396	sequence-specific DNA binding
NC3_30300	COG1396	sequence-specific DNA binding
NC3_30310	COG1733	regulation of RNA biosynthetic process
NC3_30320	COG1174	glycine betaine transport
NC3_30330	COG1732	Glycine betaine
NC3_30340	COG1174	glycine betaine transport
NC3_30350	COG0517	IMP dehydrogenase activity
NC3_30350	COG1125	glycine betaine transport
NC3_30360	COG1510	regulation of RNA biosynthetic process
NC3_30370	COG2095	MarC family integral membrane protein
NC3_30390	COG0456	acetyltransferase
NC3_30430	COG1131	(ABC) transporter
NC3_30450	COG0148	phosphopyruvate hydratase activity
NC3_30460	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NC3_30470	COG0149	triose-phosphate isomerase activity
NC3_30480	COG0126	phosphoglycerate kinase activity
NC3_30490	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NC3_30500	COG2390	Transcriptional regulator
NC3_30510	COG0833	amino acid
NC3_30520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NC3_30530	COG3829	transcription factor binding
NC3_30540	COG2186	Transcriptional regulator
NC3_30550	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NC3_30570	COG0534	Mate efflux family protein
NC3_30580	COG4608	Belongs to the ABC transporter superfamily
NC3_30590	COG0444	Belongs to the ABC transporter superfamily
NC3_30600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NC3_30610	COG0601	transmembrane transport
NC3_30620	COG0747	negative chemotaxis
NC3_30630	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NC3_30640	COG0110	maltose O-acetyltransferase activity
NC3_30650	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NC3_30660	COG2244	polysaccharide biosynthetic process
NC3_30670	COG5039	Polysaccharide pyruvyl transferase
NC3_30680	COG1216	Glycosyl transferase, family 2
NC3_30700	COG0438	transferase activity, transferring glycosyl groups
NC3_30710	COG1215	transferase activity, transferring glycosyl groups
NC3_30720	COG0438	transferase activity, transferring glycosyl groups
NC3_30730	COG1086	Polysaccharide biosynthesis protein
NC3_30740	COG0489	protein tyrosine kinase activity
NC3_30750	COG3944	biosynthesis protein
NC3_30760	COG1396	sequence-specific DNA binding
NC3_30780	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NC3_30790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NC3_30800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NC3_30810	COG0726	polysaccharide deacetylase
NC3_30820	COG0488	(ABC) transporter
NC3_30860	COG0601	transmembrane transport
NC3_30870	COG0747	negative chemotaxis
NC3_30880	COG1819	glycosyl
NC3_30910	COG0740	serine-type endopeptidase activity
NC3_30920	COG1611	Belongs to the LOG family
NC3_30930	COG1694	Mazg nucleotide pyrophosphohydrolase
NC3_30940	COG0659	secondary active sulfate transmembrane transporter activity
NC3_30950	COG0288	reversible hydration of carbon dioxide
NC3_30960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NC3_30980	COG2162	N-hydroxyarylamine O-acetyltransferase activity
NC3_30990	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NC3_31000	COG1481	regulation of sporulation
NC3_31010	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NC3_31020	COG1660	Displays ATPase and GTPase activities
NC3_31030	COG1051	belongs to the nudix hydrolase family
NC3_31040	COG0492	ferredoxin-NADP+ reductase activity
NC3_31050	COG0791	NLP P60 protein
NC3_31050	COG3883	PFAM NLP P60 protein
NC3_31060	COG0457	Tetratricopeptide repeat
NC3_31070	COG0140	phosphoribosyl-ATP diphosphatase activity
NC3_31070	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NC3_31080	COG0107	imidazoleglycerol-phosphate synthase activity
NC3_31090	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NC3_31100	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NC3_31110	COG0131	Imidazoleglycerol-phosphate dehydratase
NC3_31120	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NC3_31130	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NC3_31140	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NC3_31150	COG4990	cell redox homeostasis
NC3_31180	COG2910	NAD(P)H-binding
NC3_31190	COG1959	2 iron, 2 sulfur cluster binding
NC3_31200	COG0110	maltose O-acetyltransferase activity
NC3_31210	COG0546	phosphoglycolate phosphatase activity
NC3_31220	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NC3_31240	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NC3_31250	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NC3_31260	COG0363	glucosamine-6-phosphate deaminase activity
NC3_31270	COG2188	Transcriptional regulator
NC3_31280	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NC3_31290	COG1950	PFAM Membrane protein of
NC3_31300	COG1983	PspC domain protein
NC3_31310	COG3595	metallopeptidase activity
NC3_31340	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NC3_31360	COG4897	Protein conserved in bacteria
NC3_31370	COG3848	Pyruvate phosphate dikinase
NC3_31370	COG0574	Belongs to the PEP-utilizing enzyme family
NC3_31380	COG1309	transcriptional regulator
NC3_31390	COG2814	Major facilitator Superfamily
NC3_31410	COG0745	RESPONSE REGULATOR receiver
NC3_31420	COG5002	protein histidine kinase activity
NC3_31430	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NC3_31440	COG0463	Glycosyl transferase, family 2
NC3_31450	COG1113	amino acid transport
NC3_31460	COG0778	Nitroreductase
NC3_31470	COG1733	regulation of RNA biosynthetic process
NC3_31480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NC3_31500	COG0793	Belongs to the peptidase S41A family
NC3_31500	COG3409	Peptidoglycan-binding domain 1 protein
NC3_31510	COG0730	response to heat
NC3_31520	COG3883	PFAM NLP P60 protein
NC3_31520	COG0791	NLP P60 protein
NC3_31530	COG2177	Part of the ABC transporter FtsEX involved in
NC3_31540	COG2884	Cell division ATP-binding protein ftsE
NC3_31550	COG2010	Cytochrome c
NC3_31560	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NC3_31590	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NC3_31600	COG0653	protein targeting
NC3_31610	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NC3_31620	COG0840	transmembrane signaling receptor activity
NC3_31650	COG1516	flagellar protein fliS
NC3_31660	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NC3_31670	COG1334	flagellar protein FlaG
NC3_31680	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NC3_31690	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NC3_31710	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NC3_31720	COG4786	Flagellar basal body rod
NC3_31720	COG1256	bacterial-type flagellum assembly
NC3_31730	COG3418	PFAM FlgN family protein
NC3_31760	COG1040	competence protein
NC3_31780	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NC3_31790	COG1307	EDD domain protein, DegV family
NC3_31800	COG2197	response regulator
NC3_31810	COG4585	Histidine kinase
NC3_31820	COG1739	Uncharacterized protein family UPF0029
NC3_31830	COG1316	TRANSCRIPTIONal
NC3_31840	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NC3_31850	COG0438	transferase activity, transferring glycosyl groups
NC3_31860	COG1215	transferase activity, transferring glycosyl groups
NC3_31870	COG3206	protein involved in exopolysaccharide biosynthesis
NC3_31880	COG3307	-O-antigen
NC3_31890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NC3_31900	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NC3_31910	COG0297	glycogen (starch) synthase activity
NC3_31910	COG0438	transferase activity, transferring glycosyl groups
NC3_31920	COG2244	polysaccharide biosynthetic process
NC3_31950	COG2247	cell wall binding repeat
NC3_31950	COG0860	N-Acetylmuramoyl-L-alanine amidase
NC3_31960	COG2247	cell wall binding repeat
NC3_31960	COG0860	N-Acetylmuramoyl-L-alanine amidase
NC3_31970	COG2247	cell wall binding repeat
NC3_31970	COG2385	sporulation resulting in formation of a cellular spore
NC3_31990	COG1316	TRANSCRIPTIONal
NC3_32050	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NC3_32060	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NC3_32070	COG1134	teichoic acid transport
NC3_32080	COG1682	transport, permease protein
NC3_32090	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NC3_32110	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NC3_32120	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
NC3_32130	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NC3_32140	COG4193	domain, Protein
NC3_32150	COG1482	cell wall glycoprotein biosynthetic process
NC3_32170	COG1175	transmembrane transport
NC3_32180	COG1653	transport
NC3_32190	COG2197	response regulator
NC3_32200	COG2972	Histidine kinase
NC3_32220	COG0454	-acetyltransferase
NC3_32230	COG0800	Aldolase
NC3_32240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NC3_32250	COG1609	Transcriptional regulator
NC3_32260	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NC3_32270	COG1028	Short-chain dehydrogenase reductase Sdr
NC3_32280	COG0697	spore germination
NC3_32290	COG0814	amino acid
NC3_32320	COG2814	Major facilitator Superfamily
NC3_32330	COG1316	TRANSCRIPTIONal
NC3_32340	COG0561	phosphatase activity
NC3_32350	COG0791	NLP P60 protein
NC3_32370	COG2843	Capsule synthesis protein
NC3_32390	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NC3_32400	COG0697	spore germination
NC3_32430	COG1609	Transcriptional regulator
NC3_32440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NC3_32450	COG1869	D-ribose catabolic process
NC3_32460	COG1129	ABC transporter
NC3_32470	COG1172	Belongs to the binding-protein-dependent transport system permease family
NC3_32480	COG1879	ABC-type sugar transport system periplasmic component
NC3_32490	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NC3_32500	COG0583	DNA-binding transcription factor activity
NC3_32510	COG0028	Belongs to the TPP enzyme family
NC3_32520	COG3527	Alpha-acetolactate decarboxylase
NC3_32530	COG1522	sequence-specific DNA binding
NC3_32540	COG2059	Chromate
NC3_32550	COG2059	Chromate
NC3_32560	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NC3_32580	COG4715	Zinc finger, swim domain protein
NC3_32590	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NC3_32600	COG1366	Belongs to the anti-sigma-factor antagonist family
NC3_32600	COG2202	Pas domain
NC3_32610	COG0561	phosphatase activity
NC3_32640	COG1970	mechanosensitive ion channel activity
NC3_32650	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NC3_32660	COG0457	Tetratricopeptide repeat
NC3_32670	COG4786	Flagellar basal body rod
NC3_32680	COG4786	Flagellar basal body rod
NC3_32690	COG1077	Cell shape determining protein MreB Mrl
NC3_32700	COG1609	Transcriptional regulator
NC3_32720	COG1846	Transcriptional regulator
NC3_32730	COG2814	Major facilitator Superfamily
NC3_32740	COG0671	phosphoesterase, PA-phosphatase related
NC3_32750	COG0477	Major facilitator Superfamily
NC3_32760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NC3_32770	COG0765	amino acid transport
NC3_32780	COG1126	abc transporter atp-binding protein
NC3_32790	COG0004	ammonium transporteR
NC3_32800	COG0347	Belongs to the P(II) protein family
NC3_32810	COG0739	heme binding
NC3_32820	COG1247	-acetyltransferase
NC3_32900	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NC3_32910	COG0523	cobalamin synthesis protein
NC3_32920	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NC3_32930	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NC3_32940	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NC3_32950	COG2223	nitrite transmembrane transporter activity
NC3_32970	COG2304	oxidoreductase activity
NC3_32980	COG2304	oxidoreductase activity
NC3_32990	COG2385	sporulation resulting in formation of a cellular spore
NC3_33000	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NC3_33020	COG4836	Membrane
NC3_33040	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NC3_33050	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NC3_33060	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NC3_33070	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NC3_33080	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NC3_33090	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NC3_33100	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NC3_33110	COG0356	it plays a direct role in the translocation of protons across the membrane
NC3_33130	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NC3_33140	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NC3_33150	COG4475	Protein of unknown function (DUF436)
NC3_33160	COG0698	ribose 5-phosphate isomerase
NC3_33170	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NC3_33180	COG1971	Probably functions as a manganese efflux pump
NC3_33190	COG0009	L-threonylcarbamoyladenylate synthase
NC3_33200	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NC3_33230	COG2890	protein-(glutamine-N5) methyltransferase activity
NC3_33240	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NC3_33250	COG0789	Transcriptional regulator
NC3_33260	COG0679	Auxin Efflux Carrier
NC3_33270	COG0281	malic enzyme
NC3_33280	COG1435	thymidine kinase activity
NC3_33290	COG0254	rRNA binding
NC3_33300	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NC3_33310	COG1494	fructose-1,6-bisphosphatase
NC3_33320	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NC3_33330	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NC3_33340	COG0191	fructose-bisphosphate aldolase activity
NC3_33350	COG2204	response regulator
NC3_33360	COG4821	SIS domain
NC3_33370	COG0504	CTP synthase activity
NC3_33380	COG3343	RNA polymerase activity
NC3_33410	COG1960	acyl-CoA dehydrogenase activity
NC3_33420	COG1960	acyl-CoA dehydrogenase activity
NC3_33430	COG1250	3-hydroxyacyl-CoA dehydrogenase
NC3_33440	COG0183	Belongs to the thiolase family
NC3_33450	COG0247	lactate metabolic process
NC3_33450	COG2181	nitrate reductase activity
NC3_33460	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NC3_33470	COG4294	response to UV
NC3_33490	COG1619	proteins homologs of microcin C7 resistance protein MccF
NC3_33510	COG1132	(ABC) transporter
NC3_33520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NC3_33530	COG1619	proteins homologs of microcin C7 resistance protein MccF
NC3_33540	COG0018	arginyl-trna synthetase
NC3_33550	COG4506	Protein conserved in bacteria
NC3_33570	COG0010	Belongs to the arginase family
NC3_33580	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NC3_33590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NC3_33610	COG1994	Peptidase M50
NC3_33620	COG1942	4-Oxalocrotonate Tautomerase
NC3_33640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NC3_33650	COG0583	DNA-binding transcription factor activity
NC3_33660	COG0431	NADPH-dependent FMN reductase
NC3_33670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NC3_33680	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NC3_33690	COG0454	-acetyltransferase
NC3_33700	COG0765	amino acid transport
NC3_33720	COG0765	amino acid transport
NC3_33730	COG1126	abc transporter atp-binding protein
NC3_33740	COG3465	dGTPase activity
NC3_33750	COG1078	dGTPase activity
NC3_33760	COG4844	belongs to the
NC3_33880	COG5444	nuclease activity
NC3_33940	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NC3_33960	COG0280	phosphate acetyltransferase
NC3_33980	COG2814	Major facilitator Superfamily
NC3_33990	COG1522	sequence-specific DNA binding
NC3_34000	COG2814	Major facilitator Superfamily
NC3_34010	COG0077	Prephenate dehydratase
NC3_34020	COG1917	Cupin 2, conserved barrel domain protein
NC3_34030	COG1028	Short-chain dehydrogenase reductase Sdr
NC3_34040	COG0151	Belongs to the GarS family
NC3_34050	COG0436	Aminotransferase
NC3_34060	COG1028	Short-chain dehydrogenase reductase Sdr
NC3_34080	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
NC3_34090	COG1091	dTDP-4-dehydrorhamnose reductase activity
NC3_34100	COG1088	dTDP-glucose 4,6-dehydratase activity
NC3_34110	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NC3_34120	COG3980	spore coat polysaccharide biosynthesis protein
NC3_34130	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
NC3_34140	COG2089	acid synthase
NC3_34150	COG0456	acetyltransferase
NC3_34160	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NC3_34170	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NC3_34180	COG0463	Glycosyl transferase, family 2
NC3_34220	COG2363	Small membrane protein
NC3_34230	COG2233	PERMEase
NC3_34250	COG1012	belongs to the aldehyde dehydrogenase family
NC3_34260	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NC3_34270	COG1216	Glycosyl transferase, family 2
NC3_34290	COG0351	phosphomethylpyrimidine kinase
NC3_34360	COG1621	beta-fructofuranosidase activity
NC3_34370	COG1263	PTS System
NC3_34370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NC3_34380	COG3711	transcriptional antiterminator
NC3_34400	COG1404	Belongs to the peptidase S8 family
NC3_34410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NC3_34420	COG0778	Nitroreductase
NC3_34430	COG0772	Belongs to the SEDS family
NC3_34450	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NC3_34460	COG1845	cytochrome c oxidase, subunit III
NC3_34470	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NC3_34480	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NC3_34500	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
NC3_34510	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NC3_34520	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NC3_34550	COG2246	polysaccharide biosynthetic process
NC3_34590	COG3162	membrane
NC3_34600	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NC3_34640	COG0352	thiamine-phosphate diphosphorylase activity
NC3_34650	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NC3_34660	COG0583	DNA-binding transcription factor activity
NC3_34670	COG1380	Effector of murein hydrolase LrgA
NC3_34680	COG1346	cytolysis
NC3_34690	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NC3_34700	COG0346	lactoylglutathione lyase activity
NC3_34720	COG0765	amino acid transport
NC3_34730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NC3_34740	COG0457	Tetratricopeptide repeat
NC3_34760	COG2357	RelA SpoT domain protein
NC3_34770	COG1172	Belongs to the binding-protein-dependent transport system permease family
NC3_34780	COG1129	ABC transporter
NC3_34800	COG3420	alginic acid biosynthetic process
NC3_34810	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NC3_34830	COG1486	melibiose metabolic process
NC3_34840	COG1447	Phosphotransferase system cellobiose-specific component IIA
NC3_34850	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NC3_34860	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NC3_34870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NC3_34870	COG3711	transcriptional antiterminator
NC3_34900	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NC3_34940	COG1595	DNA-templated transcription, initiation
NC3_34960	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NC3_34970	COG4988	ABC transporter
NC3_34980	COG1294	oxidase, subunit
NC3_34990	COG1271	oxidase subunit
NC3_35000	COG1120	ATPase activity
NC3_35010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NC3_35020	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NC3_35030	COG4509	Sortase family
NC3_35080	COG5386	Cell surface protein
NC3_35090	COG5386	Cell surface protein
NC3_35100	COG1733	regulation of RNA biosynthetic process
NC3_35110	COG2514	catechol 2,3-dioxygenase activity
NC3_35120	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NC3_35120	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NC3_35130	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NC3_35130	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NC3_35150	COG0726	polysaccharide deacetylase
NC3_35160	COG1447	Phosphotransferase system cellobiose-specific component IIA
NC3_35170	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NC3_35180	COG2723	6-phospho-beta-galactosidase activity
NC3_35190	COG1312	Catalyzes the dehydration of D-mannonate
NC3_35200	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NC3_35210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NC3_35210	COG3711	transcriptional antiterminator
NC3_35260	COG1757	Na H antiporter
NC3_35270	COG1027	Aspartate ammonia-lyase
NC3_35280	COG0252	asparaginase activity
NC3_35290	COG1396	sequence-specific DNA binding
NC3_35340	COG4842	Belongs to the WXG100 family
NC3_35350	COG2195	Cleaves the N-terminal amino acid of tripeptides
NC3_35380	COG1737	Transcriptional regulator
NC3_35390	COG2084	Dehydrogenase
NC3_35410	COG2610	gluconate transmembrane transporter activity
NC3_35420	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NC3_35440	COG1136	(ABC) transporter
NC3_35450	COG2723	6-phospho-beta-galactosidase activity
NC3_35460	COG2190	(PTS) system
NC3_35460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NC3_35460	COG1263	PTS System
NC3_35470	COG3711	transcriptional antiterminator
NC3_35490	COG3878	Protein conserved in bacteria
NC3_35510	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NC3_35520	COG1122	ATPase activity
NC3_35530	COG4721	ABC-type cobalt transport system, permease component
NC3_35540	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NC3_35610	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NC3_35620	COG0778	Nitroreductase
NC3_35630	COG1846	Transcriptional regulator
NC3_35640	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NC3_35650	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NC3_35660	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NC3_35670	COG2390	Transcriptional regulator
NC3_35690	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NC3_35690	COG2755	lipolytic protein G-D-S-L family
NC3_35700	COG0477	Major facilitator Superfamily
NC3_35710	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NC3_35720	COG2226	methyltransferase
NC3_35740	COG0561	phosphatase activity
NC3_35750	COG0789	Transcriptional regulator
NC3_35760	COG0673	inositol 2-dehydrogenase activity
NC3_35770	COG0840	transmembrane signaling receptor activity
NC3_35780	COG1113	amino acid transport
NC3_35790	COG4335	DNA alkylation repair
NC3_35810	COG1070	Carbohydrate kinase
NC3_35820	COG1737	Transcriptional regulator
NC3_35900	COG0583	DNA-binding transcription factor activity
NC3_35910	COG1609	Transcriptional regulator
NC3_35920	COG2182	Extracellular solute-binding protein
NC3_35930	COG1175	transmembrane transport
NC3_35940	COG3833	ABC-type maltose transport systems, permease component
NC3_35960	COG1874	Beta-galactosidase
NC3_35970	COG2851	Citrate transporter
NC3_35990	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NC3_36000	COG1131	(ABC) transporter
NC3_36010	COG2824	Alkylphosphonate utilization operon protein PhnA
NC3_36030	COG1929	Belongs to the glycerate kinase type-1 family
NC3_36040	COG2610	gluconate transmembrane transporter activity
NC3_36050	COG3835	regulator
NC3_36060	COG1309	transcriptional regulator
NC3_36070	COG2814	Major facilitator Superfamily
NC3_36090	COG1136	(ABC) transporter
NC3_36110	COG0457	Tetratricopeptide repeat
NC3_36120	COG3711	transcriptional antiterminator
NC3_36130	COG2723	6-phospho-beta-galactosidase activity
NC3_36140	COG2190	(PTS) system
NC3_36140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NC3_36140	COG1263	PTS System
NC3_36190	COG0494	nUDIX hydrolase
NC3_36220	COG1113	amino acid transport
NC3_36230	COG1609	Transcriptional regulator
NC3_36240	COG2814	Major facilitator Superfamily
NC3_36250	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NC3_36260	COG2814	Major facilitator Superfamily
NC3_36370	COG5444	nuclease activity
NC3_36390	COG2723	6-phospho-beta-galactosidase activity
NC3_36410	COG2188	Transcriptional regulator
NC3_36430	COG0384	phenazine biosynthesis protein PhzF
NC3_36440	COG0583	DNA-binding transcription factor activity
NC3_36480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NC3_36510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NC3_36550	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NC3_36570	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NC3_36590	COG4720	Psort location CytoplasmicMembrane, score
NC3_36630	COG0456	acetyltransferase
NC3_36640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NC3_36650	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NC3_36660	COG4853	Protein conserved in bacteria
NC3_36670	COG4863	YycH protein
NC3_36680	COG5002	protein histidine kinase activity
NC3_36690	COG0745	RESPONSE REGULATOR receiver
NC3_36700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NC3_36720	COG2311	Membrane
NC3_36730	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NC3_36750	COG0346	lactoylglutathione lyase activity
NC3_36760	COG0305	Participates in initiation and elongation during chromosome replication
NC3_36790	COG2819	hydrolase of the alpha beta superfamily
NC3_36800	COG2207	Transcriptional regulator
NC3_36800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NC3_36810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NC3_36820	COG2819	hydrolase of the alpha beta superfamily
NC3_36830	COG3093	addiction module antidote protein HigA
NC3_36840	COG2807	transmembrane transport
NC3_36850	COG0359	binds to the 23S rRNA
NC3_36860	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
NC3_36870	COG4241	membrane
NC3_36880	COG1227	inorganic diphosphatase activity
NC3_36900	COG1595	DNA-templated transcription, initiation
NC3_36920	COG0753	catalase activity
NC3_36930	COG0655	NAD(P)H dehydrogenase (quinone) activity
NC3_36940	COG0400	carboxylic ester hydrolase activity
NC3_36950	COG0346	lactoylglutathione lyase activity
NC3_36960	COG1174	glycine betaine transport
NC3_36970	COG0517	IMP dehydrogenase activity
NC3_36970	COG1125	glycine betaine transport
NC3_36980	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NC3_36990	COG0629	single-stranded DNA binding
NC3_37000	COG0360	Binds together with S18 to 16S ribosomal RNA
NC3_37010	COG0012	GTP binding
NC3_37020	COG4481	Protein conserved in bacteria
NC3_37050	COG3949	Membrane
NC3_37070	COG1475	DNA binding
NC3_37080	COG1192	Involved in chromosome partitioning
NC3_37100	COG1475	DNA binding
NC3_37110	COG0357	Ribosomal RNA small subunit methyltransferase G
NC3_37120	COG0445	tRNA wobble uridine modification
NC3_37130	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NC3_37140	COG1847	R3H domain protein
NC3_37150	COG0706	membrane insertase activity
NC3_37160	COG0594	ribonuclease P activity
NC3_37170	COG0230	Belongs to the bacterial ribosomal protein bL34 family