locus-tag	class	description
AKO66_00005	ENOG4105CRK	lysyL-tRNA synthetase
AKO66_00010	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AKO66_00020	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AKO66_00025	ENOG4105KRF	dihydroneopterin aldolase
AKO66_00030	ENOG4105EEI	dihydropteroate synthase
AKO66_00035	ENOG41082R7	4-amino-4-deoxychorismate lyase EC 4.1.3.38
AKO66_00040	ENOG4105DDQ	anthranilate synthase
AKO66_00045	ENOG4105CRQ	synthase (Component I)
AKO66_00050	ENOG4105C6T	cysteine synthase
AKO66_00055	ENOG4107U48	ppic-type peptidyL-prolyl cis-trans isomerase
AKO66_00060	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AKO66_00065	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
AKO66_00070	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AKO66_00075	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AKO66_00080	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AKO66_00110	ENOG41060GV	RNA binding s1 domain protein
AKO66_00125	ENOG4105VYY	sporulation protein yabp
AKO66_00130	ENOG41082I2	s4 domain protein
AKO66_00135	ENOG4108IY2	MazG family
AKO66_00145	ENOG4108M14	stage v sporulation protein t
AKO66_00150	ENOG4108JA2	transcriptioN-repair coupling factor
AKO66_00160	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AKO66_00165	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AKO66_00170	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AKO66_00175	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AKO66_00185	ENOG4105KME	endoribonuclease L-psp
AKO66_00190	ENOG4105DFT	pur operon repressor
AKO66_00195	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AKO66_00200	ENOG4105XEW	small acid-soluble spore protein
AKO66_00205	ENOG4105W42	Veg protein
AKO66_00210	ENOG4105XFA	sporulation peptidase YabG
AKO66_00215	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AKO66_00225	ENOG41069ER	domain protein
AKO66_00230	ENOG4105F8V	Hydrolase, tatD family
AKO66_00235	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AKO66_00240	ENOG4105KRN	Transcriptional regulator, abrb family
AKO66_00245	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
AKO66_00250	ENOG4105VC4	domain protein
AKO66_00255	ENOG41060K3	Methyltransferase
AKO66_00260	ENOG41063V3	Involved in initiation control of chromosome replication (By similarity)
AKO66_00265	ENOG4105MA4	psp1 domain protein
AKO66_00270	ENOG4105FA2	dna polymerase iii
AKO66_00275	ENOG4105XVJ	Protein of unknown function (DUF327)
AKO66_00280	ENOG4105X0R	protein from nitrogen regulatory protein P-II
AKO66_00285	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AKO66_00290	ENOG4105CXN	decarboxylase
AKO66_00295	ENOG4105CDW	Resistance protein
AKO66_00335	ENOG41067KS	pro-sigma K processing
AKO66_00345	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AKO66_00350	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AKO66_00355	ENOG4105C6E	dna polymerase iii
AKO66_00360	ENOG4108Z6B	deaminase
AKO66_00365	ENOG4105GTG	Isochorismatase
AKO66_00370	ENOG4105VRS	hydrolase family 18
AKO66_00380	ENOG4105ZMH	deoxynucleoside kinase
AKO66_00390	ENOG4105FKZ	Methyl-accepting chemotaxis
AKO66_00395	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AKO66_00400	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
AKO66_00405	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
AKO66_00410	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AKO66_00420	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AKO66_00455	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AKO66_00460	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AKO66_00470	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AKO66_00475	ENOG410848D	S4 domain protein YaaA
AKO66_00480	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AKO66_00485	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AKO66_00495	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AKO66_00500	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AKO66_00510	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AKO66_00515	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AKO66_00520	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AKO66_00535	ENOG4107QJE	Chromosome Partitioning Protein
AKO66_00540	ENOG4105FA0	parb-like partition protein
AKO66_00545	ENOG4108ZDA	Sporulation protein YyaC
AKO66_00565	ENOG4105VDK	protein, conserved in bacteria
AKO66_00570	ENOG4105C3G	gtp-binding protein
AKO66_00575	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AKO66_00580	ENOG4108UUM	single-stranded DNA-binding protein
AKO66_00585	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AKO66_00590	ENOG4108IJ8	ABC transporter
AKO66_00595	ENOG4105E90	ABC transporter
AKO66_00600	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
AKO66_00605	ENOG4105FBA	Phospholipase Carboxylesterase
AKO66_00610	ENOG4105CS1	NAD(P)H quinone oxidoreductase
AKO66_00615	ENOG4105CH6	catalase
AKO66_00625	ENOG4105JVQ	RNA Polymerase
AKO66_00630	ENOG4108P49	AntiSigma factor
AKO66_00635	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
AKO66_00640	ENOG4108XMW	Membrane
AKO66_00645	ENOG4105BZR	domain protein
AKO66_00650	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AKO66_00655	ENOG4105DJ2	Major Facilitator Superfamily
AKO66_00660	ENOG4108SA1	esterase
AKO66_00670	ENOG410874W	AraC family transcriptional regulator
AKO66_00675	ENOG4105NIV	Esterase
AKO66_00690	ENOG4106K80	
AKO66_00695	ENOG4105CDU	Replicative dna helicase
AKO66_00700	ENOG4105HB7	Glyoxalase Bleomycin resistance protein (Dioxygenase
AKO66_00705	ENOG4106A3M	Cytochrome p-450
AKO66_00710	ENOG4105ST3	Transcriptional regulator
AKO66_00715	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AKO66_00730	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AKO66_00755	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AKO66_00760	ENOG4105BZU	Histidine kinase
AKO66_00775	ENOG4105Q2H	domain protein
AKO66_00780	ENOG4105C0H	protease
AKO66_00785	ENOG4105WQG	acetyltransferase
AKO66_00805	ENOG4108V7D	UPF0397 protein
AKO66_00815	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
AKO66_00820	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AKO66_00850	ENOG4105EYF	MMPL domain protein
AKO66_00860	ENOG4105BZU	Histidine kinase
AKO66_00875	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
AKO66_00895	ENOG41080UQ	Transcriptional regulator
AKO66_00900	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AKO66_00915	ENOG4108S3Y	transcriptional regulator
AKO66_00920	ENOG4105C5Y	PTS System
AKO66_00925	ENOG4105CS2	ec 3.2.1.21
AKO66_00960	ENOG4105E2X	shikimate dehydrogenase
AKO66_00970	ENOG4105ETE	Transcriptional regulator (LacI family
AKO66_00975	ENOG4105C85	amino acid
AKO66_00990	ENOG4105M6F	mutator MutT protein
AKO66_01015	ENOG4105C5Y	PTS System
AKO66_01020	ENOG4105CS2	ec 3.2.1.21
AKO66_01025	ENOG4105CID	antiterminator
AKO66_01030	ENOG410780I	phosphoprotein phosphatase activity
AKO66_01040	ENOG4105C19	ABC transporter
AKO66_01050	ENOG4107Y80	Major Facilitator superfamily
AKO66_01055	ENOG4105YA8	Transcriptional regulator
AKO66_01060	ENOG4107VHA	regulatoR
AKO66_01065	ENOG4107QQ0	gntp family
AKO66_01070	ENOG4105BZW	Glycerate kinase
AKO66_01075	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
AKO66_01080	ENOG4105CJ1	ABC, transporter
AKO66_01085	ENOG4108TU7	Inherit from COG: (ABC) transporter
AKO66_01095	ENOG4105D4T	Citrate transporter
AKO66_01100	ENOG4105C4C	beta-galactosidase
AKO66_01110	ENOG4105EG2	ABC transporter, permease
AKO66_01120	ENOG4107FKK	extracellular solute-binding protein family 1
AKO66_01130	ENOG4105DUM	transcriptional regulator, lysR family
AKO66_01170	ENOG4106KNT	transcriptional regulator
AKO66_01175	ENOG4105CMG	Carbohydrate kinase
AKO66_01180	ENOG4105C6Z	Gluconate
AKO66_01185	ENOG4105F1N	DNA alkylation repair
AKO66_01195	ENOG4105FKZ	Methyl-accepting chemotaxis
AKO66_01200	ENOG4105EE0	oxidoreductase
AKO66_01205	ENOG4105W1Y	Transcriptional regulator
AKO66_01210	ENOG410667J	hydrolase
AKO66_01220	ENOG4105HMZ	Methyltransferase
AKO66_01225	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AKO66_01230	ENOG4105DXI	Major Facilitator superfamily
AKO66_01235	ENOG4105EXC	Acyl-transferase
AKO66_01245	ENOG4107RHR	regulatoR
AKO66_01250	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
AKO66_01255	ENOG4105D9N	nucleoside
AKO66_01260	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
AKO66_01265	ENOG4105FS7	Transcriptional regulator
AKO66_01270	ENOG4108TVJ	Nitroreductase
AKO66_01275	ENOG41067V3	Antibiotic biosynthesis monooxygenase
AKO66_01280	ENOG4107G87	m6 family metalloprotease domain protein
AKO66_01310	ENOG4105ETU	transcriptional activator (TenA
AKO66_01315	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
AKO66_01320	ENOG4108JJB	ABC transporter
AKO66_01325	ENOG4108W7F	transporter, permease
AKO66_01335	ENOG4108XI2	Domain of unknown function (DUF1963)
AKO66_01340	ENOG4105CID	antiterminator
AKO66_01345	ENOG4105C5Y	PTS System
AKO66_01350	ENOG4105CS2	ec 3.2.1.21
AKO66_01380	ENOG4105C6Z	Gluconate
AKO66_01390	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AKO66_01395	ENOG4106KNT	transcriptional regulator
AKO66_01410	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
AKO66_01440	ENOG4108IMY	Transcriptional regulator
AKO66_01445	ENOG4105HDK	L-asparaginase
AKO66_01450	ENOG4108IJ0	Aspartate ammonia-lyase
AKO66_01455	ENOG4105DFD	Na H antiporter
AKO66_01480	ENOG4105EMD	TRANSCRIPTIONal
AKO66_01485	ENOG4105CK1	PTS System
AKO66_01490	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
AKO66_01495	ENOG4105CS2	ec 3.2.1.21
AKO66_01500	ENOG4105VZJ	PTS System
AKO66_01505	ENOG4105VCP	PTS System
AKO66_01510	ENOG4107BJW	polysaccharide deacetylase
AKO66_01520	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AKO66_01525	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AKO66_01530	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
AKO66_01535	ENOG4105KVH	Transcriptional regulator
AKO66_01540	ENOG4106ST0	Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity)
AKO66_01545	ENOG4106ST0	Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity)
AKO66_01570	ENOG4105KFN	sortase, SrtB family
AKO66_01575	ENOG4108HUF	Transporter
AKO66_01580	ENOG4105DQ5	transport system permease protein
AKO66_01585	ENOG4105E0A	ABC, transporter
AKO66_01590	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AKO66_01595	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AKO66_01600	ENOG4108JJ9	ABC, transporter
AKO66_01605	ENOG4108JJ8	(ABC) transporter
AKO66_01610	ENOG4108J20	pectate lyase
AKO66_01630	ENOG4107R37	Glutamate dehydrogenase
AKO66_01645	ENOG4105EMD	TRANSCRIPTIONal
AKO66_01650	ENOG4105VZJ	PTS System
AKO66_01655	ENOG4105CK1	PTS System
AKO66_01660	ENOG4105VCP	PTS System
AKO66_01665	ENOG4105F8D	glycoside hydrolase family 4
AKO66_01680	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AKO66_01685	ENOG4108M26	parallel beta-helix repeat protein
AKO66_01690	ENOG4108QGH	periplasmic
AKO66_01695	ENOG4105C2J	ABC transporter
AKO66_01700	ENOG4105CNN	ABC, transporter
AKO66_01715	ENOG4107R0W	ABC transporter
AKO66_01720	ENOG4105E5Q	amino acid AbC transporter
AKO66_01740	ENOG4105DR4	Methyltransferase
AKO66_01745	ENOG41067MG	lrgb family
AKO66_01755	ENOG4105CMU	LysR family (Transcriptional regulator
AKO66_01760	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
AKO66_01765	ENOG4107U6I	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AKO66_01795	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AKO66_01805	ENOG4105WH5	Teichoic acid glycosylation protein
AKO66_01820	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
AKO66_01825	ENOG4105CMR	udp-glucose 4-epimerase
AKO66_01840	ENOG4105E2S	oxidase) subunit II
AKO66_01845	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AKO66_01850	ENOG4105CCU	oxidase (Subunit III)
AKO66_01855	ENOG41060D1	Quinol oxidase
AKO66_01870	ENOG4108DBC	nitroreductase
AKO66_01875	ENOG4105DEN	Luciferase family
AKO66_01885	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
AKO66_01900	ENOG4105C5Y	PTS System
AKO66_01920	ENOG4105DWF	phosphomethylpyrimidine kinase
AKO66_01930	ENOG4108RJ9	Glycosyl transferase, family 2
AKO66_01935	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AKO66_01940	ENOG4105C26	Dehydrogenase
AKO66_01985	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AKO66_01990	ENOG41067MN	Spore coat polysaccharide biosynthesis protein spsD
AKO66_02000	ENOG4107TY6	Acylneuraminate cytidylyltransferase
AKO66_02005	ENOG4107P9E	Inherit from COG: pseudaminic acid biosynthesis-associated protein PseG
AKO66_02010	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
AKO66_02015	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AKO66_02020	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
AKO66_02025	ENOG4107ZIM	Dtdp-4-dehydrorhamnose 3,5-epimerase
AKO66_02035	ENOG4105CHM	Aminotransferase
AKO66_02040	ENOG4108V3M	Inherit from COG: acetyl-CoA carboxylase biotin carboxylase
AKO66_02045	ENOG4105CHR	reductase
AKO66_02050	ENOG4106CHD	Bacilysin biosynthesis protein bacB
AKO66_02055	ENOG41061WN	bacilysin biosynthesis protein
AKO66_02060	ENOG4105FCW	Major Facilitator superfamily
AKO66_02070	ENOG4105F27	Major Facilitator
AKO66_02075	ENOG4107JTW	chlorite dismutase
AKO66_02080	ENOG4108IJ2	phosphate acetyltransferase
AKO66_02090	ENOG4105JSC	dimethylmenaquinone methyltransferase
AKO66_02120	ENOG4107EV6	Inherit from COG: YD repeat protein
AKO66_02145	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
AKO66_02155	ENOG4107QZ7	Cellulose synthase catalytic subunit
AKO66_02165	ENOG4108VCI	transcription factor, rsfa family
AKO66_02170	ENOG4105QAT	UPF0741 protein
AKO66_02175	ENOG4105DCI	Phosphohydrolase
AKO66_02190	ENOG41069HH	4-oxalocrotonate tautomerase
AKO66_02195	ENOG4108Z4T	Peptidase M50
AKO66_02200	ENOG4108XFG	YwhD family
AKO66_02205	ENOG4105BZ4	penicillin-binding protein
AKO66_02210	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
AKO66_02215	ENOG4105CYW	agmatinase
AKO66_02225	ENOG410684U	Domain of unknown function (DUF1934)
AKO66_02230	ENOG4105C75	arginyL-tRNA synthetase
AKO66_02240	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AKO66_02245	ENOG4105BZ1	(ABC) transporter
AKO66_02250	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
AKO66_02270	ENOG4105DF6	Fe-S oxidoreductase
AKO66_02280	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AKO66_02285	ENOG4105C1G	acyl-Coa dehydrogenase
AKO66_02290	ENOG4105C1G	acyl-Coa dehydrogenase
AKO66_02315	ENOG4105CJ1	ABC, transporter
AKO66_02330	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AKO66_02340	ENOG410812K	response regulator receiver protein
AKO66_02345	ENOG4105D2N	Aldolase
AKO66_02355	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AKO66_02360	ENOG4105CBT	Fructose-1,6-bisphosphatase
AKO66_02365	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AKO66_02370	ENOG41082DI	50s ribosomal protein l31
AKO66_02375	ENOG4107104	thymidine kinase
AKO66_02380	ENOG4105C6K	Malic enzyme
AKO66_02385	ENOG4107TT2	Auxin Efflux Carrier
AKO66_02395	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AKO66_02400	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AKO66_02410	ENOG4108ZXQ	stage ii sporulation protein r
AKO66_02420	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AKO66_02430	ENOG4107WAU	Protein tyrosine phosphatase
AKO66_02435	ENOG4108YZG	isomerase
AKO66_02440	ENOG4108UIC	UPF0340 protein
AKO66_02445	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AKO66_02450	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AKO66_02460	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
AKO66_02480	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AKO66_02485	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AKO66_02490	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AKO66_02495	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AKO66_02505	ENOG4106778	Protein of unknown function (DUF1146)
AKO66_02515	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AKO66_02530	ENOG4108TF4	von Willebrand factor, type A
AKO66_02535	ENOG4108J2R	molybdopterin oxidoreductase
AKO66_02540	ENOG4105FCD	Major Facilitator
AKO66_02545	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
AKO66_02555	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AKO66_02560	ENOG4105CKI	cobalamin synthesis protein
AKO66_02565	ENOG4105WDJ	50S ribosomal protein L33
AKO66_02575	ENOG4107TCE	N-acetyltransferase
AKO66_02580	ENOG4105FRN	stage II sporulation protein
AKO66_02590	ENOG4105BZU	Histidine kinase
AKO66_02595	ENOG4105CDA	abc transporter atp-binding protein
AKO66_02600	ENOG4105E5Q	amino acid AbC transporter
AKO66_02605	ENOG4105EAB	amino acid AbC transporter
AKO66_02610	ENOG41080V3	Major Facilitator superfamily
AKO66_02615	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
AKO66_02620	ENOG4105CZM	Major Facilitator
AKO66_02625	ENOG4107MII	Sugar-specific transcriptional regulator TrmB
AKO66_02630	ENOG4105MT0	Sporulation transcriptional regulator spoiiid
AKO66_02635	ENOG4105DFF	Rod shape-determining protein mreb
AKO66_02645	ENOG4105CGA	flagellar basal-body rod protein FlgG
AKO66_02655	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AKO66_02660	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AKO66_02675	ENOG410667J	hydrolase
AKO66_02680	ENOG4105BZU	Histidine kinase
AKO66_02685	ENOG4105C0D	helicase
AKO66_02690	ENOG4105KBK	Zinc finger, swim domain protein
AKO66_02695	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AKO66_02700	ENOG4105FGV	Chromate
AKO66_02705	ENOG4105CAH	Chromate
AKO66_02715	ENOG4107FQX	Alpha-acetolactate decarboxylase
AKO66_02725	ENOG4107RSM	transcriptional regulator
AKO66_02730	ENOG4107XC4	flavin reductase domain protein, FMN-binding
AKO66_02735	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
AKO66_02740	ENOG4105CNN	ABC, transporter
AKO66_02745	ENOG4105C2J	ABC transporter
AKO66_02750	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
AKO66_02755	ENOG4108RVA	ribokinase
AKO66_02760	ENOG4105ETE	Transcriptional regulator (LacI family
AKO66_02780	ENOG4105N98	Capsule biosynthesis protein capB
AKO66_02790	ENOG4105PNM	synthesis protein
AKO66_02795	ENOG4105K4H	Nlp p60 protein
AKO66_02800	ENOG4105J7I	hydrolase
AKO66_02805	ENOG4108KGH	TRANSCRIPTIONal
AKO66_02810	ENOG4105C54	Major Facilitator superfamily
AKO66_02815	ENOG4107RGC	Glycosyl transferase, family 2
AKO66_02820	ENOG4108NHD	germination protein
AKO66_02835	ENOG4105CHR	reductase
AKO66_02840	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
AKO66_02845	ENOG4108M60	Transcriptional regulator
AKO66_02850	ENOG4105D7K	pfkb domain protein
AKO66_02855	ENOG4108UHU	Aldolase
AKO66_02860	ENOG4105I4A	GCN5-related N-acetyltransferase
AKO66_02870	ENOG4105C2F	Histidine kinase
AKO66_02875	ENOG4105WH1	Two component transcriptional regulator luxr family
AKO66_02880	ENOG4108JP0	extracellular solute-binding protein family 1
AKO66_02885	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
AKO66_02895	ENOG4105DG6	mannose-6-phosphate isomerase
AKO66_02900	ENOG4107SJB	teichoic acid biosynthesis
AKO66_02910	ENOG4107RZX	Teichoic acid biosynthesis protein
AKO66_02920	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
AKO66_02930	ENOG4107SJB	teichoic acid biosynthesis
AKO66_02935	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
AKO66_02945	ENOG4107SJB	teichoic acid biosynthesis
AKO66_02950	ENOG4105CPF	Cell wall formation (By similarity)
AKO66_02960	ENOG4105K64	Glycosyl transferase, family 2
AKO66_02970	ENOG4105EY8	ABC transporter
AKO66_02975	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AKO66_02980	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
AKO66_02985	ENOG4108KGH	TRANSCRIPTIONal
AKO66_02995	ENOG4105JFG	SpoIID LytB domain protein
AKO66_03000	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AKO66_03005	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AKO66_03015	ENOG4105D3Q	Sugar transferase
AKO66_03020	ENOG4105PSV	Polysaccharide Biosynthesis Protein
AKO66_03025	ENOG4107RA4	Glycosyl transferase (Group 1
AKO66_03030	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AKO66_03035	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AKO66_03040	ENOG4105QZI	O-Antigen Polymerase
AKO66_03055	ENOG4107EF8	Glycosyl transferase (Group 1
AKO66_03060	ENOG4105ESV	Glycosyl transferase, family 4
AKO66_03065	ENOG4108KGH	TRANSCRIPTIONal
AKO66_03070	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
AKO66_03075	ENOG4105BZU	Histidine kinase
AKO66_03080	ENOG4105WH1	Two component transcriptional regulator luxr family
AKO66_03100	ENOG41081UC	Inherit from COG: Competence protein
AKO66_03105	ENOG4105RU3	
AKO66_03120	ENOG4105E1Q	flagellar hook-associated protein
AKO66_03125	ENOG4105DTJ	flagellar hook-associated protein
AKO66_03130	ENOG4105MKD	
AKO66_03135	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
AKO66_03140	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
AKO66_03145	ENOG41083S7	flagellar protein FlaG
AKO66_03150	ENOG4107RT6	flagellar hook-associated
AKO66_03155	ENOG4105MQ3	flagellar protein FliS
AKO66_03170	ENOG4105C8Q	Methyl-accepting chemotaxis
AKO66_03175	ENOG4105MS2	ribosomal subunit Interface protein
AKO66_03185	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AKO66_03210	ENOG4105CAK	Cell division ATP-binding protein ftsE
AKO66_03215	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
AKO66_03230	ENOG4105CN1	protease
AKO66_03245	ENOG4105KVH	Transcriptional regulator
AKO66_03250	ENOG4108RCM	Nitroreductase
AKO66_03260	ENOG4105CKK	Glycosyl transferase, family 2
AKO66_03265	ENOG4105EDW	glycosyl transferase, family 39
AKO66_03270	ENOG4105BZU	Histidine kinase
AKO66_03275	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AKO66_03290	ENOG4105MKU	Transcriptional regulator
AKO66_03310	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AKO66_03315	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AKO66_03330	ENOG4108PY7	
AKO66_03335	ENOG41067S9	phage shock protein C, PspC
AKO66_03340	ENOG41086DT	Membrane protein of unknown function
AKO66_03345	ENOG41088CQ	domain protein
AKO66_03350	ENOG4105FDP	GntR family transcriptional regulator
AKO66_03355	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
AKO66_03360	ENOG4105CE4	GlcNAc 6-P deacetylase
AKO66_03365	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
AKO66_03370	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AKO66_03375	ENOG4105HKU	nucleoside recognition domain-containing protein
AKO66_03380	ENOG4107XGZ	Hydrolase
AKO66_03385	ENOG4108S4C	acetyltransferase
AKO66_03390	ENOG4108Z40	Transcriptional regulator
AKO66_03395	ENOG4108RYK	Nad-dependent epimerase dehydratase
AKO66_03410	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
AKO66_03415	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AKO66_03420	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AKO66_03425	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AKO66_03430	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AKO66_03435	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AKO66_03440	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AKO66_03445	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AKO66_03455	ENOG4105Z8B	NlpC/P60 family
AKO66_03460	ENOG4105C3M	thioredoxin reductase
AKO66_03465	ENOG4108Z4K	mutator MutT protein
AKO66_03470	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AKO66_03475	ENOG4105CHW	UPF0052 protein
AKO66_03480	ENOG4105CIE	May be required for sporulation (By similarity)
AKO66_03485	ENOG4105KRI	phosphocarrier protein (HPr
AKO66_03490	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
AKO66_03500	ENOG4105C5I	Dehydrogenase
AKO66_03505	ENOG4108V2W	Carbonate dehydratase
AKO66_03510	ENOG4105CHH	sulfate transporter
AKO66_03515	ENOG4105TPC	MazG nucleotide pyrophosphohydrolase domain
AKO66_03520	ENOG4108URH	decarboxylase
AKO66_03525	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AKO66_03615	ENOG410682Q	Phage transcriptional regulator, ArpU
AKO66_03675	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AKO66_03720	ENOG4108FKH	Transglycosylase SLT domain
AKO66_03740	ENOG41068G1	
AKO66_03760	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AKO66_03785	ENOG4108MES	Periplasmic binding protein
AKO66_03795	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
AKO66_03800	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AKO66_03815	ENOG4108S9F	abc transporter, atp-binding protein
AKO66_03825	ENOG4108ZJ4	polysaccharide deacetylase
AKO66_03830	ENOG4105DQ5	transport system permease protein
AKO66_03835	ENOG4105EHG	Permease protein
AKO66_03840	ENOG4108V5C	ABC transporter
AKO66_03855	ENOG4105HTX	biosynthesis protein
AKO66_03860	ENOG4108QV3	biosynthesis protein
AKO66_03870	ENOG4108PQP	glycosyl transferase group 1
AKO66_03875	ENOG4105K64	Glycosyl transferase, family 2
AKO66_03880	ENOG4108KMV	Glycosyl transferase (Group 1
AKO66_03885	ENOG41068W6	Capsular polysaccharide biosynthesis protein
AKO66_03890	ENOG4107QRS	glycosyltransferase group 2 family protein
AKO66_03905	ENOG4105D3Q	Sugar transferase
AKO66_03910	ENOG4105MME	Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family
AKO66_03915	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AKO66_03920	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
AKO66_03925	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AKO66_03930	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AKO66_03935	ENOG4105C3U	ABC transporter
AKO66_03940	ENOG4108JQ7	(ABC) transporter
AKO66_03945	ENOG4107R73	Mate efflux family protein
AKO66_03955	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AKO66_03960	ENOG4105JXH	GntR family transcriptional regulator
AKO66_03965	ENOG4108JUB	Transcriptional regulator
AKO66_03970	ENOG4105C8Y	Acetylornithine aminotransferase
AKO66_03985	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AKO66_03990	ENOG4105BZA	Phosphoglycerate kinase
AKO66_03995	ENOG4105CP7	Triose-phosphate isomerase
AKO66_04005	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AKO66_04035	ENOG4108W0I	acetyltransferase
AKO66_04045	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
AKO66_04050	ENOG4107HG4	Transcriptional regulator
AKO66_04055	ENOG4108IJ8	ABC transporter
AKO66_04060	ENOG4105E90	ABC transporter
AKO66_04065	ENOG4108HQR	Glycine betaine
AKO66_04070	ENOG4105R40	Glycine betaine carnitine choline
AKO66_04075	ENOG4105KVH	Transcriptional regulator
AKO66_04100	ENOG4105XZU	Preprotein translocase, subunit SecG
AKO66_04110	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AKO66_04115	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AKO66_04135	ENOG4105BZU	Histidine kinase
AKO66_04145	ENOG4105VPX	protein, conserved in bacteria
AKO66_04150	ENOG410681U	heavy metal transport detoxification protein
AKO66_04155	ENOG4105C59	p-type ATPase
AKO66_04165	ENOG4108IJ0	Aspartate ammonia-lyase
AKO66_04180	ENOG4105W1N	transcriptional regulator
AKO66_04185	ENOG4105IIP	Membrane
AKO66_04190	ENOG4105DSE	periplasmic solute binding protein
AKO66_04195	ENOG4105CC5	ABC transporter
AKO66_04200	ENOG4105DIK	(ABC) transporter
AKO66_04205	ENOG4105C59	p-type ATPase
AKO66_04210	ENOG4107ZQN	disulfide bond
AKO66_04220	ENOG4105EN6	Membrane
AKO66_04225	ENOG4107SUZ	Sodium/hydrogen exchanger family
AKO66_04230	ENOG4105EVU	fructokinase
AKO66_04240	ENOG4105E0C	molybdate abc transporter
AKO66_04245	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
AKO66_04250	ENOG4107QZ2	Sulfatase
AKO66_04255	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
AKO66_04275	ENOG4105D5Q	Arginine ornithine antiporter
AKO66_04285	ENOG4105DQ5	transport system permease protein
AKO66_04290	ENOG4105EHG	Permease protein
AKO66_04295	ENOG4105E0A	ABC, transporter
AKO66_04300	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AKO66_04310	ENOG4105D2H	Uronic isomerase
AKO66_04315	ENOG4107KJX	Transcriptional regulator
AKO66_04320	ENOG4107QZW	Altronate oxidoreductase
AKO66_04325	ENOG4105CTX	dehydratase
AKO66_04335	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
AKO66_04340	ENOG4105EHG	Permease protein
AKO66_04345	ENOG4105E0A	ABC, transporter
AKO66_04350	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AKO66_04355	ENOG4105C0A	alcohol dehydrogenase
AKO66_04370	ENOG4108JUA	Transcriptional regulator
AKO66_04375	ENOG4107S2N	Type III effector Hrp-dependent
AKO66_04380	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
AKO66_04385	ENOG4105CHR	reductase
AKO66_04390	ENOG4108WBT	adenosyltransferase
AKO66_04400	ENOG41087YS	Phage shock protein A
AKO66_04415	ENOG4105ENE	Histidine kinase
AKO66_04420	ENOG4105WH1	Two component transcriptional regulator luxr family
AKO66_04445	ENOG4105C9Q	fumarate hydratase class II
AKO66_04450	ENOG41067SE	Tetr family transcriptional regulator
AKO66_04455	ENOG4105F3H	Histidine kinase
AKO66_04465	ENOG4105C0H	protease
AKO66_04470	ENOG4105E1F	short-chain dehydrogenase reductase
AKO66_04480	ENOG4105E0A	ABC, transporter
AKO66_04505	ENOG4105CHU	acetyl-coa acetyltransferase
AKO66_04510	ENOG4105C1G	acyl-Coa dehydrogenase
AKO66_04515	ENOG41080E8	Transcriptional regulator, Spx MgsR family
AKO66_04520	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AKO66_04545	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AKO66_04550	ENOG4108UMI	ABC transporter, permease
AKO66_04555	ENOG4105D01	(LipO)protein
AKO66_04565	ENOG4105C3K	feS assembly ATPase SufC
AKO66_04570	ENOG4105JRK	feS assembly protein SufD
AKO66_04575	ENOG4105C9B	Cysteine desulfurase
AKO66_04580	ENOG4108UNV	SUF system FeS assembly protein, NifU family
AKO66_04585	ENOG4105DIW	FeS assembly protein SUFB
AKO66_04600	ENOG4108IG5	Transcriptional regulator
AKO66_04610	ENOG4107YCK	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
AKO66_04625	ENOG4105DHF	Membrane
AKO66_04630	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AKO66_04635	ENOG4108SWU	Histidine kinase
AKO66_04660	ENOG4108MES	Periplasmic binding protein
AKO66_04665	ENOG4105DQ5	transport system permease protein
AKO66_04670	ENOG4108IHU	transport system permease protein
AKO66_04685	ENOG4108K8S	endonuclease I
AKO66_04690	ENOG4105C5R	Aminotransferase
AKO66_04700	ENOG4105F0F	Oxalate decarboxylase
AKO66_04705	ENOG4105G9B	Transcriptional regulator
AKO66_04710	ENOG4105I3N	Conserved Protein
AKO66_04715	ENOG4107R8B	5'-nucleotidase
AKO66_04720	ENOG4105KZD	Domain of unknown function (DUF1805)
AKO66_04725	ENOG4108YTE	sporulation protein YunB
AKO66_04740	ENOG4105FAA	peptidase M23
AKO66_04750	ENOG4106EGE	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
AKO66_04755	ENOG4105MMD	transcriptional regulator
AKO66_04765	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
AKO66_04770	ENOG4108W5N	phosphatidylglycerophosphatase a
AKO66_04780	ENOG4105C5I	Dehydrogenase
AKO66_04785	ENOG4105D6E	homoserine dehydrogenase
AKO66_04790	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
AKO66_04800	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
AKO66_04805	ENOG41083MR	nifu domain-containing protein
AKO66_04825	ENOG4105ZKE	UPF0349 protein
AKO66_04830	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AKO66_04835	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AKO66_04850	ENOG4105CAY	ferredoxin--nadp reductase
AKO66_04855	ENOG4105CEP	NADH dehydrogenase
AKO66_04865	ENOG41069ER	domain protein
AKO66_04875	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AKO66_04890	ENOG4105DCF	alanine dehydrogenase
AKO66_04895	ENOG4108K8K	Transcriptional regulator
AKO66_04930	ENOG410904N	short-chain dehydrogenase reductase
AKO66_04950	ENOG4105C02	permease
AKO66_04980	ENOG4105DAP	Nicotinate phosphoribosyltransferase
AKO66_04985	ENOG4105D58	Diguanylate phosphodiesterase
AKO66_05010	ENOG4105BZU	Histidine kinase
AKO66_05020	ENOG4105KA0	thioesterase Superfamily protein
AKO66_05025	ENOG4105KJM	monovalent cation h antiporter subunit g
AKO66_05035	ENOG4105SC1	monovalent cation H antiporter subunit E
AKO66_05040	ENOG4108JPZ	Monovalent cation H antiporter subunit D
AKO66_05045	ENOG4108ZE9	Monovalent cation H antiporter subunit C
AKO66_05050	ENOG4105HC0	Na H antiporter
AKO66_05055	ENOG4105D65	subunit l
AKO66_05075	ENOG4105UIB	(ABC) transporter
AKO66_05080	ENOG4108JQ9	ABC transporter
AKO66_05085	ENOG4105DIH	basic membrane
AKO66_05090	ENOG4108MRH	transcriptional regulatory protein
AKO66_05105	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
AKO66_05110	ENOG4105BZ4	penicillin-binding protein
AKO66_05125	ENOG4105Y38	Kinase-associated protein B
AKO66_05130	ENOG4108HGU	Histidine kinase
AKO66_05135	ENOG4105C87	Aminotransferase class I and II
AKO66_05145	ENOG4108MUZ	hydrolase
AKO66_05150	ENOG4108ZB6	transcriptional regulator AsnC family
AKO66_05155	ENOG4105CHM	Aminotransferase
AKO66_05165	ENOG4105WG9	Conserved Protein
AKO66_05170	ENOG4107QW4	alcohol dehydrogenase
AKO66_05180	ENOG4107QYV	phosphohexose isomerase
AKO66_05195	ENOG4107PBV	potassium channel
AKO66_05210	ENOG4105C37	(CBS) domain
AKO66_05215	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
AKO66_05220	ENOG4105EA8	2-Nitropropane dioxygenase
AKO66_05235	ENOG4105C8Q	Methyl-accepting chemotaxis
AKO66_05240	ENOG4105C8Q	Methyl-accepting chemotaxis
AKO66_05245	ENOG4105C8Q	Methyl-accepting chemotaxis
AKO66_05250	ENOG4105C8Q	Methyl-accepting chemotaxis
AKO66_05255	ENOG4108Z0Z	intracellular protease Pfpi family
AKO66_05260	ENOG4105EE0	oxidoreductase
AKO66_05275	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AKO66_05285	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
AKO66_05310	ENOG4105QBX	endodeoxyribonuclease RusA
AKO66_05330	ENOG4105IG6	Phage terminase, large subunit
AKO66_05335	ENOG4108MDF	Phage Portal Protein
AKO66_05360	ENOG41060SN	
AKO66_05375	ENOG4105PQS	phage protein
AKO66_05380	ENOG4105FR7	XkdM protein, phage-like element PBSX
AKO66_05385	ENOG4105MTC	XkdN-like protein
AKO66_05390	ENOG4108FKH	Transglycosylase SLT domain
AKO66_05390	ENOG4108FKH	Transglycosylase SLT domain
AKO66_05395	ENOG4108WZM	domain protein
AKO66_05400	ENOG4105X7F	
AKO66_05410	ENOG4105MFU	Protein of unknown function (DUF2634)
AKO66_05415	ENOG41066EA	baseplate J family protein
AKO66_05420	ENOG410906S	phage-like element pbsx protein xkdt
AKO66_05445	ENOG41068G1	
AKO66_05450	ENOG41068G1	
AKO66_05475	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
AKO66_05490	ENOG4105TRT	Transcriptional regulator
AKO66_05495	ENOG4105C26	Dehydrogenase
AKO66_05500	ENOG4108JB8	alcohol dehydrogenase
AKO66_05505	ENOG4106DF1	
AKO66_05515	ENOG4105DZ6	Band 7 protein
AKO66_05520	ENOG4105CNI	cell division protein FtsW
AKO66_05525	ENOG4105CNI	cell division protein FtsW
AKO66_05535	ENOG4105VRR	gCN5-related N-acetyltransferase
AKO66_05540	ENOG4105N67	Proton-coupled thiamine transporter YuaJ
AKO66_05675	ENOG4108606	TspO/MBR family
AKO66_05685	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
AKO66_05690	ENOG4105E4F	Isochorismate synthase
AKO66_05695	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
AKO66_05700	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
AKO66_05705	ENOG4108IPT	Naphthoate synthase
AKO66_05715	ENOG4105DTQ	mandelate racemase muconate lactonizing
AKO66_05735	ENOG4105NRA	50s ribosomal protein l31 type b
AKO66_05740	ENOG4105DSE	periplasmic solute binding protein
AKO66_05745	ENOG4108V2W	Carbonate dehydratase
AKO66_05750	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AKO66_05755	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
AKO66_05770	ENOG4108RMU	ferritin dps family protein
AKO66_05795	ENOG4106FN3	tellurium resistance protein
AKO66_05805	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
AKO66_05815	ENOG4105D2X	ABC transporter substrate-binding protein
AKO66_05835	ENOG4105EWK	phytoene
AKO66_05855	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AKO66_05860	ENOG4105CAQ	asparagine synthetase
AKO66_05865	ENOG4108Z0R	Transferase
AKO66_05870	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
AKO66_05880	ENOG4108N23	SpoOM-related protein
AKO66_05890	ENOG4105N5T	Radical SAM Protein
AKO66_05910	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
AKO66_05915	ENOG4105DVE	abc transporter atp-binding protein
AKO66_05925	ENOG4105C19	ABC transporter
AKO66_05930	ENOG4107R34	abc transporter permease protein
AKO66_05935	ENOG4106UBQ	
AKO66_05940	ENOG4105BZU	Histidine kinase
AKO66_05950	ENOG4105C8T	Leucyl-tRNA synthetase
AKO66_05955	ENOG4105NTD	Inherit from COG: Hydrolase
AKO66_05965	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
AKO66_05975	ENOG4105CV8	reductase
AKO66_05980	ENOG4105F27	Major Facilitator
AKO66_05985	ENOG4105KVH	Transcriptional regulator
AKO66_05990	ENOG41075H3	AraC family transcriptional regulator
AKO66_06000	ENOG4105F5H	Glycosyl Hydrolase Family 88
AKO66_06010	ENOG4105DDC	Oxidoreductase domain protein
AKO66_06015	ENOG4105MU9	integral membrane protein
AKO66_06020	ENOG41085GJ	domain protein
AKO66_06030	ENOG4106611	bacteriocin immunity
AKO66_06035	ENOG4105C94	Transporter
AKO66_06045	ENOG4105CBX	hi0933 family
AKO66_06060	ENOG4105YW5	deoR family transcriptional regulator
AKO66_06065	ENOG4105C7N	Xanthine uracil vitamin C permease
AKO66_06070	ENOG4107QSE	Dipeptidase
AKO66_06075	ENOG4107UIE	peptidase
AKO66_06080	ENOG4105C6T	cysteine synthase
AKO66_06085	ENOG4107F58	2'-5' rna ligase
AKO66_06100	ENOG4108V15	phosphotransferase enzyme family
AKO66_06110	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AKO66_06115	ENOG4105C8F	Beta-lactamase domain protein
AKO66_06120	ENOG4105C6K	Malic enzyme
AKO66_06135	ENOG4108V0E	nucleoside 2-deoxyribosyltransferase YtoQ
AKO66_06150	ENOG4108NKM	UPF0354 protein
AKO66_06155	ENOG4108VDD	TRNA binding domain protein
AKO66_06165	ENOG4105DFU	Cell wall formation (By similarity)
AKO66_06185	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AKO66_06190	ENOG4105ETE	Transcriptional regulator (LacI family
AKO66_06195	ENOG4105DGU	Histone deacetylase
AKO66_06200	ENOG4105W87	Cbs domain
AKO66_06205	ENOG4105F1V	Acetoin utilization protein
AKO66_06215	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AKO66_06220	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
AKO66_06225	ENOG4108KTS	Acetyltransferase and hydrolase with the alpha beta hydrolase fold
AKO66_06245	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AKO66_06255	ENOG4105U5Y	Transcriptional regulator
AKO66_06285	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
AKO66_06295	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AKO66_06300	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
AKO66_06315	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
AKO66_06320	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AKO66_06330	ENOG4105C19	ABC transporter
AKO66_06340	ENOG4105CNI	cell division protein FtsW
AKO66_06345	ENOG4105EWM	Histidine kinase
AKO66_06350	ENOG4105CJZ	response regulator
AKO66_06360	ENOG4108S01	response regulator
AKO66_06365	ENOG4108ZGX	Histidine kinase
AKO66_06370	ENOG4105ECK	Fatty Acid Desaturase
AKO66_06375	ENOG4105C1J	atp-dependent rna helicase
AKO66_06380	ENOG4108KKH	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AKO66_06385	ENOG4105D07	Signal peptide peptidase, SppA
AKO66_06390	ENOG4105VK3	rdd domain containing protein
AKO66_06400	ENOG4105KBJ	sporulation protein ytfj
AKO66_06405	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
AKO66_06415	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AKO66_06420	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
AKO66_06425	ENOG4105CDH	Citrulline--aspartate ligase
AKO66_06430	ENOG4105CH7	arginosuccinase
AKO66_06445	ENOG4105E8R	UPF0173 metal-dependent hydrolase
AKO66_06460	ENOG4105SFS	phosphoesterase RecJ domain protein
AKO66_06465	ENOG4106EVM	
AKO66_06475	ENOG4105VV2	
AKO66_06480	ENOG4105C0B	DNA polymerase III (alpha subunit)
AKO66_06485	ENOG4105C6K	Malic enzyme
AKO66_06490	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AKO66_06500	ENOG4105CTQ	phosphohexokinase
AKO66_06505	ENOG4105CA9	Pyruvate kinase
AKO66_06510	ENOG4105FS0	cytoplasmic membrane protein
AKO66_06515	ENOG4108REF	Sporulation integral membrane protein ytvi
AKO66_06520	ENOG4107CWS	Protein of unknown function (DUF441)
AKO66_06525	ENOG4105BZN	citrate synthase
AKO66_06530	ENOG4108HMX	isocitrate dehydrogenase (NADP)
AKO66_06535	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AKO66_06540	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AKO66_06545	ENOG4105BZU	Histidine kinase
AKO66_06550	ENOG4105C2M	dna polymerase I
AKO66_06555	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AKO66_06565	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AKO66_06570	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AKO66_06575	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
AKO66_06585	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AKO66_06605	ENOG4108TDW	sporulation protein YtxC
AKO66_06610	ENOG4105C22	threonyL-tRNA synthetase
AKO66_06615	ENOG4107SDU	Methyl-accepting chemotaxis
AKO66_06620	ENOG4105U0R	haloacid dehalogenase-like hydrolase
AKO66_06630	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AKO66_06635	ENOG4105VJV	50s ribosomal protein L35
AKO66_06640	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AKO66_06645	ENOG410696E	Membrane
AKO66_06655	ENOG4105CN9	Peptidase m42 family protein
AKO66_06665	ENOG41067MF	small acid-soluble spore protein
AKO66_06670	ENOG4108RWN	rrna methyltransferase
AKO66_06675	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AKO66_06680	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AKO66_06685	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AKO66_06690	ENOG410687F	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
AKO66_06700	ENOG4105DCG	PHP domain protein
AKO66_06705	ENOG4105C98	muts2 protein
AKO66_06720	ENOG4105CEY	Amp-dependent synthetase and ligase
AKO66_06725	ENOG4107Z3H	Transcriptional regulator, TetR family
AKO66_06730	ENOG41060WC	Enoyl-CoA hydratase
AKO66_06735	ENOG4105BZJ	Electron transfer flavoprotein
AKO66_06740	ENOG4105C10	Electron transfer flavoprotein
AKO66_06745	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
AKO66_06750	ENOG4105K63	Thioredoxin
AKO66_06755	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AKO66_06760	ENOG4105CFH	Aspartokinase
AKO66_06770	ENOG4108NU2	Succinate dehydrogenase cytochrome b558 subunit
AKO66_06780	ENOG4105E33	succinate dehydrogenase
AKO66_06790	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AKO66_06795	ENOG4105C7F	AcnD-accessory protein PrpF
AKO66_06800	ENOG4108KAM	Transcriptional regulator
AKO66_06810	ENOG4105PFC	Transcriptional regulator
AKO66_06815	ENOG41067TZ	transcriptional regulator, MarR family
AKO66_06820	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
AKO66_06825	ENOG4108XJQ	germination protein
AKO66_06830	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AKO66_06835	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AKO66_06840	ENOG4105M59	Phosphodiesterase, mj0936 family
AKO66_06880	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
AKO66_06885	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
AKO66_06895	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
AKO66_06905	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
AKO66_06910	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AKO66_06915	ENOG4105C7K	acetolactate synthase
AKO66_06920	ENOG4108ZP8	Acetolactate synthase small subunit
AKO66_06925	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AKO66_06930	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AKO66_06935	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AKO66_06940	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AKO66_06945	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AKO66_06955	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AKO66_06960	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AKO66_06965	ENOG4108IUQ	atp-dependent protease
AKO66_06970	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AKO66_06975	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AKO66_06995	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AKO66_07005	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AKO66_07015	ENOG4105D52	delta-aminolevulinic acid dehydratase
AKO66_07020	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AKO66_07025	ENOG41068KH	stage VI sporulation protein D
AKO66_07030	ENOG4106AR7	Spore coat protein
AKO66_07040	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AKO66_07045	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AKO66_07050	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
AKO66_07060	ENOG4108Z03	MAF-like protein
AKO66_07065	ENOG4105W5Q	DNA repair protein (RadC
AKO66_07070	ENOG4105DFF	Rod shape-determining protein mreb
AKO66_07075	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
AKO66_07080	ENOG4105YHC	Rod shape-determining protein MreD
AKO66_07085	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
AKO66_07090	ENOG4107QMS	site-determining protein
AKO66_07105	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AKO66_07110	ENOG4105X36	(ribosomal) protein
AKO66_07115	ENOG4105K46	50S ribosomal protein l27
AKO66_07125	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AKO66_07135	ENOG4105CQC	Prephenate dehydratase
AKO66_07150	ENOG4108IYU	L-aspartate oxidase
AKO66_07155	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AKO66_07160	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
AKO66_07165	ENOG4106678	morphogenetic protein associated with SpoVID
AKO66_07180	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AKO66_07200	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AKO66_07205	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AKO66_07210	ENOG41061AI	Protein of unknown function (DUF2905)
AKO66_07215	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AKO66_07220	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AKO66_07225	ENOG4105VIE	preprotein translocase, subunit YajC
AKO66_07230	ENOG4105NAP	
AKO66_07235	ENOG4108QG2	Membrane
AKO66_07240	ENOG4105CKP	Polysaccharide Biosynthesis Protein
AKO66_07250	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AKO66_07255	ENOG4105NCW	Trka-c domain protein
AKO66_07260	ENOG41067VP	Protein of unknown function (DUF1049)
AKO66_07265	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AKO66_07270	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AKO66_07275	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AKO66_07280	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AKO66_07285	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AKO66_07290	ENOG4105CUT	histidyl-tRNA synthetase
AKO66_07295	ENOG4105C9M	aspartyl-trna synthetase
AKO66_07300	ENOG4105CUZ	uba thif-type nad fad binding protein
AKO66_07305	ENOG4105D1H	recombination factor protein RarA
AKO66_07315	ENOG4105C3J	Cysteine desulfurase
AKO66_07320	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AKO66_07330	ENOG4105C7H	Helicase, RecD TraA family
AKO66_07340	ENOG41060CR	
AKO66_07345	ENOG4105DRP	amino acid AbC transporter
AKO66_07350	ENOG4105EAD	ABC transporter
AKO66_07355	ENOG4105CT1	(ABC) transporter
AKO66_07360	ENOG4105CDA	abc transporter atp-binding protein
AKO66_07365	ENOG4105C02	permease
AKO66_07375	ENOG4105VBH	UPF0297 protein
AKO66_07380	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AKO66_07385	ENOG4105VPH	UPF0473 protein
AKO66_07395	ENOG4107ZYJ	bioY protein
AKO66_07400	ENOG4107F3J	Amp-dependent synthetase and ligase
AKO66_07410	ENOG4105HHA	aminodeoxychorismate lyase
AKO66_07415	ENOG4108VQJ	O-methyltransferase
AKO66_07420	ENOG4105XYU	peptidase (U32 family)
AKO66_07425	ENOG4105CFP	Peptidase U32
AKO66_07430	ENOG4107S03	uridine kinase
AKO66_07435	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AKO66_07440	ENOG4107XRG	penicillin-binding protein
AKO66_07455	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
AKO66_07460	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
AKO66_07470	ENOG4105C28	cystathionine
AKO66_07485	ENOG4105E2A	Dehydrogenase
AKO66_07490	ENOG4107V2S	Transcriptional regulator
AKO66_07505	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
AKO66_07520	ENOG4105E5Q	amino acid AbC transporter
AKO66_07540	ENOG4105FDT	acyl-CoA dehydrogenase
AKO66_07545	ENOG4108HWY	Beta-lactamase
AKO66_07575	ENOG4105KVH	Transcriptional regulator
AKO66_07580	ENOG4108VA3	3-hexulose-6-phosphate synthase
AKO66_07585	ENOG41080HJ	6-phospho 3-hexuloisomerase
AKO66_07595	ENOG4105NTK	Transcriptional repressor Mpra
AKO66_07605	ENOG4105CMD	Transcriptional regulator, GntR family
AKO66_07620	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
AKO66_07625	ENOG4107QNK	)-transporter
AKO66_07645	ENOG4108IJ3	abc transporter atp-binding protein
AKO66_07680	ENOG4108ZJ4	polysaccharide deacetylase
AKO66_07705	ENOG4105DMD	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AKO66_07730	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
AKO66_07735	ENOG4105CQW	ribosome biogenesis GTPase YqeH
AKO66_07740	ENOG4105E2X	shikimate dehydrogenase
AKO66_07745	ENOG410812S	Rna-binding protein
AKO66_07750	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AKO66_07755	ENOG4108WF2	Metal Dependent Phosphohydrolase
AKO66_07765	ENOG4108D32	Methyltransferase
AKO66_07775	ENOG4105KQC	Competence protein
AKO66_07780	ENOG4108UK2	deaminase
AKO66_07785	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
AKO66_07790	ENOG4105TQK	DNA polymerase iii, delta' subunit
AKO66_07805	ENOG4108ZRV	stage ii sporulation protein p
AKO66_07815	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AKO66_07820	ENOG4105CSA	Coproporphyrinogen iii oxidase
AKO66_07825	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
AKO66_07830	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AKO66_07840	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AKO66_07845	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AKO66_07850	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AKO66_07855	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AKO66_07870	ENOG4105KTH	gatB Yqey
AKO66_07875	ENOG4105F7J	membrane-bound serine protease
AKO66_07880	ENOG4105DI5	UPF0365 protein
AKO66_07890	ENOG41068P3	sporulation protein YqfC
AKO66_07895	ENOG4105EI1	sporulation protein yqfd
AKO66_07900	ENOG4105C9A	Phoh family
AKO66_07905	ENOG4105CTJ	Metal Dependent Phosphohydrolase
AKO66_07910	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AKO66_07915	ENOG4107YR5	Diacylglycerol kinase
AKO66_07920	ENOG4105KG3	cytidine deaminase
AKO66_07925	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AKO66_07930	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
AKO66_07935	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
AKO66_07940	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
AKO66_07950	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
AKO66_07955	ENOG4108UPT	UPF0178 protein
AKO66_07960	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AKO66_07965	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AKO66_07980	ENOG4105EGD	dinuclear metal center protein, YbgI family
AKO66_07985	ENOG4108IUH	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AKO66_08000	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
AKO66_08005	ENOG41069ZM	Protein of unknown function (DUF2624)
AKO66_08010	ENOG4108JYZ	YitT family
AKO66_08015	ENOG4105FDK	ABC transporter
AKO66_08020	ENOG4105FAV	ABC, transporter
AKO66_08025	ENOG4105N80	Ferric uptake regulator, Fur family
AKO66_08030	ENOG41066F8	ROK family
AKO66_08035	ENOG4108U5J	'-nucleotidase
AKO66_08040	ENOG41063Y9	
AKO66_08045	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AKO66_08055	ENOG4105D9U	N-acetyltransferase
AKO66_08065	ENOG4105SXS	Protein of unknown function (DUF456)
AKO66_08070	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AKO66_08080	ENOG4107RF6	penicillin-binding protein
AKO66_08085	ENOG4105CVA	phosphate
AKO66_08090	ENOG4105C8U	phosphate abc transporter
AKO66_08095	ENOG4105E2Z	phosphate ABC transporter (Permease
AKO66_08100	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AKO66_08105	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AKO66_08110	ENOG41068DG	YceG-like family
AKO66_08125	ENOG4105WDJ	50S ribosomal protein L33
AKO66_08130	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AKO66_08140	ENOG4107ZXI	Rhomboid family
AKO66_08155	ENOG4105E0M	Sulfatase
AKO66_08175	ENOG4105C5X	domain protein
AKO66_08210	ENOG4106855	Competence protein
AKO66_08250	ENOG4105VFR	signal peptidase
AKO66_08270	ENOG4105C0D	helicase
AKO66_08275	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AKO66_08285	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AKO66_08290	ENOG4105WZW	rhodanese family
AKO66_08295	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
AKO66_08300	ENOG4105KST	dependent repressor
AKO66_08315	ENOG4105CBJ	Metal-dependent enzyme
AKO66_08325	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
AKO66_08330	ENOG4105DC7	peptidase M24
AKO66_08335	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AKO66_08345	ENOG4105CD2	stage iii sporulation protein aa
AKO66_08350	ENOG4105KR5	Stage iii sporulation protein
AKO66_08355	ENOG4108CQH	stage III sporulation protein AC
AKO66_08360	ENOG4105KQ4	Stage iii sporulation protein ad
AKO66_08370	ENOG410644B	Stage III sporulation protein af
AKO66_08390	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AKO66_08395	ENOG4108ZSR	alkaline shock protein
AKO66_08400	ENOG4105M7K	Involved in the transcription termination process (By similarity)
AKO66_08405	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AKO66_08410	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AKO66_08415	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AKO66_08420	ENOG4105CTB	Polyprenyl synthetase
AKO66_08425	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AKO66_08430	ENOG4105DX0	Hemolysin A
AKO66_08435	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
AKO66_08440	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AKO66_08445	ENOG4105S1Z	Stage IV sporulation protein B
AKO66_08450	ENOG4107QQR	Sporulation
AKO66_08460	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
AKO66_08465	ENOG4106CCJ	Protein of unknown function (DUF2627)
AKO66_08470	ENOG4108JUB	Transcriptional regulator
AKO66_08480	ENOG4107RDP	Dehydrogenase
AKO66_08485	ENOG4105CKM	Branched-chain carboxylic acid kinase
AKO66_08500	ENOG4105CPP	Dehydrogenase, E1 component
AKO66_08505	ENOG4105C7S	Dehydrogenase
AKO66_08515	ENOG4109050	May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG)
AKO66_08520	ENOG4108Y6J	UPF0403 protein
AKO66_08525	ENOG4108HW3	(ABC) transporter
AKO66_08530	ENOG4105E5Q	amino acid AbC transporter
AKO66_08535	ENOG4105CDA	abc transporter atp-binding protein
AKO66_08540	ENOG4108QEG	Membrane
AKO66_08545	ENOG4108VZI	ErfK ybiS ycfS ynhG family protein
AKO66_08550	ENOG4108ZVT	methylmalonyl-coA epimerase
AKO66_08555	ENOG4108HNZ	carboxyl transferase
AKO66_08560	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
AKO66_08565	ENOG4108V3W	Chemotaxis protein, CheW
AKO66_08570	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
AKO66_08580	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AKO66_08585	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
AKO66_08590	ENOG4105CSC	Glucose uptake protein
AKO66_08595	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
AKO66_08605	ENOG4105VZJ	PTS System
AKO66_08610	ENOG4105VCP	PTS System
AKO66_08615	ENOG4105CK1	PTS System
AKO66_08620	ENOG4105CS2	ec 3.2.1.21
AKO66_08625	ENOG4108TZY	GntR Family Transcriptional Regulator
AKO66_08630	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
AKO66_08635	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AKO66_08640	ENOG4105XT2	Transcriptional regulator
AKO66_08650	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AKO66_08665	ENOG4105II7	pyrroline-5-carboxylate reductase
AKO66_08670	ENOG41069FQ	Metallo-beta-lactamase superfamily
AKO66_08675	ENOG4108IXY	short-chain dehydrogenase reductase
AKO66_08685	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AKO66_08695	ENOG4105E5W	Transporter
AKO66_08705	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AKO66_08715	ENOG4108XET	gCN5-related N-acetyltransferase
AKO66_08720	ENOG4105RHY	Pfam:UPF0157
AKO66_08725	ENOG4108YQE	rare lipoprotein a
AKO66_08730	ENOG4106HZJ	
AKO66_08760	ENOG4105CPC	Aldo Keto reductase
AKO66_08765	ENOG4108YZ4	nudix hydrolase
AKO66_08775	ENOG4107YB6	acetyltransferase, (GNAT) family
AKO66_08790	ENOG4105MZ9	stage II sporulation protein m
AKO66_08795	ENOG4105I3K	Ferric uptake regulator, Fur family
AKO66_08805	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AKO66_08810	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
AKO66_08815	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
AKO66_08820	ENOG4105DZ1	carboxypeptidase
AKO66_08825	ENOG41082AN	stage II sporulation protein
AKO66_08830	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
AKO66_08835	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AKO66_08850	ENOG41090VF	Stage v sporulation protein ac
AKO66_08855	ENOG4105CZ3	stage V sporulation protein ad
AKO66_08865	ENOG4105G6R	Stage v sporulation protein ae
AKO66_08875	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AKO66_08880	ENOG4105PTM	secreted protein
AKO66_08885	ENOG4107ZE5	PPIases accelerate the folding of proteins
AKO66_08910	ENOG4108R6K	riboflavin synthase, subunit alpha
AKO66_08920	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AKO66_08935	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
AKO66_08940	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AKO66_08950	ENOG4105DZ1	carboxypeptidase
AKO66_08955	ENOG4108JIC	nucleoside recognition domain protein
AKO66_08965	ENOG4105FE9	pseudouridine synthase
AKO66_08975	ENOG4107TWT	Cytochrome c biogenesis protein
AKO66_08980	ENOG4105CRE	cytochrome C
AKO66_08985	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AKO66_08990	ENOG4105BZU	Histidine kinase
AKO66_09010	ENOG4108JQ1	Dehydrogenase
AKO66_09015	ENOG4108SAX	Membrane
AKO66_09025	ENOG4105T7X	
AKO66_09030	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AKO66_09035	ENOG4105I7S	Abortive infection protein
AKO66_09050	ENOG4107RGJ	metallophosphoesterase
AKO66_09065	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
AKO66_09070	ENOG4108PNU	Involved in the degradation of specific anti-sigma factors (By similarity)
AKO66_09080	ENOG4105MSI	germination protein ypeb
AKO66_09095	ENOG4105CAT	Cytidine monophosphate kinase
AKO66_09100	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AKO66_09115	ENOG4105S2F	
AKO66_09120	ENOG41065D1	
AKO66_09125	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AKO66_09130	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AKO66_09145	ENOG4105DXU	ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity)
AKO66_09150	ENOG4105K70	DNA-binding protein
AKO66_09155	ENOG4105EUJ	GTP cyclohydrolase i
AKO66_09165	ENOG4105XXQ	heptaprenyl diphosphate synthase component I
AKO66_09170	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AKO66_09175	ENOG4105EAH	synthase
AKO66_09180	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AKO66_09185	ENOG4105BZU	Histidine kinase
AKO66_09190	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AKO66_09195	ENOG4105D49	3-dehydroquinate synthase
AKO66_09200	ENOG4105KHN	chorismate mutase
AKO66_09210	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AKO66_09215	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AKO66_09220	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
AKO66_09225	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AKO66_09230	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AKO66_09235	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AKO66_09245	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AKO66_09250	ENOG41068YB	TPR repeat-containing protein
AKO66_09255	ENOG4108SXZ	UPF0302 protein
AKO66_09270	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AKO66_09290	ENOG4108JYZ	YitT family
AKO66_09295	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
AKO66_09300	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AKO66_09305	ENOG4108Z5K	methylglyoxal synthase
AKO66_09310	ENOG4105FJR	Lmbe family
AKO66_09315	ENOG4105CPK	Glycosyl transferase (Group 1
AKO66_09320	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AKO66_09330	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AKO66_09335	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AKO66_09340	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
AKO66_09345	ENOG4105DVT	helicase
AKO66_09365	ENOG4105CSM	endonuclease III
AKO66_09375	ENOG4105BZ4	penicillin-binding protein
AKO66_09380	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
AKO66_09420	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AKO66_09530	ENOG4105CAR	Terminase, large subunit
AKO66_09610	ENOG4108S4A	n-acetylmuramoyl-l-alanine amidase
AKO66_09640	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AKO66_09675	ENOG4108I5C	dEAD DEAH box helicase
AKO66_09680	ENOG4107X2U	Inherit from COG: Exonuclease-like protein
AKO66_09685	ENOG4108UKS	UPF0398 protein
AKO66_09690	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
AKO66_09695	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AKO66_09705	ENOG4105DVT	helicase
AKO66_09710	ENOG4105CTD	carboxy-peptidase
AKO66_09720	ENOG4105C2W	permease
AKO66_09725	ENOG4107VMI	polysaccharide deacetylase
AKO66_09730	ENOG4105RHY	Pfam:UPF0157
AKO66_09735	ENOG41065KQ	synthase
AKO66_09745	ENOG410890F	Dynamin family
AKO66_09765	ENOG41081VK	Ribonuclease
AKO66_09800	ENOG4108QBV	Monogalactosyldiacylglycerol synthase
AKO66_09805	ENOG4105CVG	Homoserine O-transsuccinylase
AKO66_09810	ENOG4105CKU	formyltetrahydrofolate synthetase
AKO66_09815	ENOG4108V06	Glutathione peroxidase
AKO66_09830	ENOG4105C01	Dihydroxy-acid dehydratase
AKO66_09835	ENOG4108Y6J	UPF0403 protein
AKO66_09840	ENOG4107YX5	Pfam:DUF548
AKO66_09855	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AKO66_09860	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
AKO66_09870	ENOG4108UT2	hemolysin iii
AKO66_09880	ENOG4105C7B	Threonine dehydratase
AKO66_09895	ENOG4108KF3	Electron transport protein SCO1 SenC
AKO66_09900	ENOG41090WU	lipolytic protein G-D-S-L family
AKO66_09905	ENOG4105QZP	Uncharacterized protein conserved in bacteria (DUF2140)
AKO66_09930	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AKO66_09935	ENOG4105E0X	reductase
AKO66_09940	ENOG4105C5E	polysaccharide biosynthesis protein
AKO66_09970	ENOG4108JUB	Transcriptional regulator
AKO66_09975	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
AKO66_09985	ENOG4105VSD	UPF0346 protein
AKO66_09995	ENOG410841Q	phosphoesterase PA-phosphatase related protein
AKO66_10000	ENOG4106Z5R	
AKO66_10005	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
AKO66_10010	ENOG4108VXD	carboxy-peptidase
AKO66_10030	ENOG4105E1V	na solute symporter
AKO66_10060	ENOG4105FR1	rard protein
AKO66_10080	ENOG4107QMU	Mate efflux family protein
AKO66_10090	ENOG4105K4H	Nlp p60 protein
AKO66_10100	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
AKO66_10105	ENOG4107T89	von Willebrand factor, type A
AKO66_10110	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
AKO66_10115	ENOG4105C7S	Dehydrogenase
AKO66_10120	ENOG4105C09	Bile acid
AKO66_10125	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AKO66_10130	ENOG4105EWU	Squalene--hopene cyclase
AKO66_10140	ENOG4105C26	Dehydrogenase
AKO66_10160	ENOG4105SCY	DNAK suppressor
AKO66_10165	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AKO66_10170	ENOG41069ER	domain protein
AKO66_10180	ENOG4108SJC	Membrane
AKO66_10190	ENOG4105DXD	2-methylcitrate dehydratase
AKO66_10195	ENOG4105CR4	methylisocitrate lyase
AKO66_10205	ENOG4105CUB	amino acid
AKO66_10210	ENOG4105KTU	Transcriptional regulator, arsr family
AKO66_10220	ENOG4105D29	Helix-turn-helix type 11 domain protein
AKO66_10230	ENOG4108W8B	Beta-lactamase domain protein
AKO66_10250	ENOG4105FVX	
AKO66_10260	ENOG4108Z7R	Chaperone CsaA
AKO66_10265	ENOG4105CT4	transporter
AKO66_10275	ENOG4105E2R	ROK family
AKO66_10285	ENOG4105CMG	Carbohydrate kinase
AKO66_10295	ENOG4108J2R	molybdopterin oxidoreductase
AKO66_10305	ENOG4105II7	pyrroline-5-carboxylate reductase
AKO66_10310	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AKO66_10315	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AKO66_10320	ENOG4108UYN	gCN5-related N-acetyltransferase
AKO66_10325	ENOG41090E6	transcriptional regulator MERR family
AKO66_10330	ENOG4105BZ1	(ABC) transporter
AKO66_10340	ENOG4105C5Q	Transcriptional regulator
AKO66_10345	ENOG4105CBC	glutamate synthase
AKO66_10350	ENOG4105BZ8	glutamate synthase
AKO66_10365	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AKO66_10370	ENOG4108IFG	nitrite reductase, (NAD(P)H)
AKO66_10375	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
AKO66_10380	ENOG4105H67	Protein of unknown function (DUF421)
AKO66_10385	ENOG4105NBR	Pectinesterase
AKO66_10390	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
AKO66_10395	ENOG4107QJQ	Mate efflux family protein
AKO66_10420	ENOG4105DEN	Luciferase family
AKO66_10430	ENOG4105EXQ	uroporphyrinogen iii synthase hem4
AKO66_10435	ENOG4107T5V	SNARE associated Golgi
AKO66_10440	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AKO66_10460	ENOG4108B31	Spore germination protein
AKO66_10470	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
AKO66_10475	ENOG4105CQB	FAD linked oxidase domain protein
AKO66_10490	ENOG41090U3	tautomerase
AKO66_10495	ENOG4105E98	transcriptional regulator DeoR family
AKO66_10505	ENOG4105F32	YngK protein
AKO66_10510	ENOG4105C1G	acyl-Coa dehydrogenase
AKO66_10515	ENOG4105CEY	Amp-dependent synthetase and ligase
AKO66_10520	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AKO66_10525	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
AKO66_10530	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
AKO66_10535	ENOG4105E39	Enoyl-CoA hydratase
AKO66_10540	ENOG4107QX3	carboxylase
AKO66_10545	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AKO66_10555	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AKO66_10560	ENOG4105C26	Dehydrogenase
AKO66_10580	ENOG4107RZC	phospholipase d
AKO66_10585	ENOG4105HX0	Transcriptional regulator
AKO66_10590	ENOG4105DE4	1-phosphofructokinase
AKO66_10595	ENOG4105DM4	PTS System
AKO66_10600	ENOG4105DM4	PTS System
AKO66_10650	ENOG4105IG6	Phage terminase, large subunit
AKO66_10655	ENOG4108MDF	Phage Portal Protein
AKO66_10660	ENOG4106CGH	Phage Mu protein F like protein
AKO66_10675	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
AKO66_10690	ENOG4105UP7	3-epimerase
AKO66_10705	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
AKO66_10710	ENOG4105I1K	ABC transporter
AKO66_10725	ENOG4107SYN	Glycosyl hydrolases family 43
AKO66_10735	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AKO66_10755	ENOG4105C5Y	PTS System
AKO66_10760	ENOG4105CS2	ec 3.2.1.21
AKO66_10790	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
AKO66_10810	ENOG4105C6T	cysteine synthase
AKO66_10820	ENOG41082YX	Transcriptional regulator, arsr family
AKO66_10825	ENOG4107R5R	arsenical pump membrane protein
AKO66_10830	ENOG4108UXE	Protein tyrosine phosphatase
AKO66_10835	ENOG4108UW5	maltose o-acetyltransferase
AKO66_10840	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AKO66_10845	ENOG4106UW1	Major Facilitator superfamily
AKO66_10860	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AKO66_10865	ENOG4105K4P	CoA-binding domain protein
AKO66_10870	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
AKO66_10875	ENOG4105W8X	HesB YadR YfhF-family protein
AKO66_10880	ENOG4105MI2	
AKO66_10900	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AKO66_10905	ENOG4108I0Z	Aconitate hydratase
AKO66_10935	ENOG4107QIV	Cytochrome c biogenesis protein
AKO66_10945	ENOG4105VXM	UPF0154 protein
AKO66_10955	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AKO66_10960	ENOG4105VPS	UPF0291 protein
AKO66_10965	ENOG4108SVB	resolvase
AKO66_10975	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AKO66_10990	ENOG4106SCS	STAS domain
AKO66_10995	ENOG4105WFK	nuclease
AKO66_11000	ENOG4105EDW	glycosyl transferase, family 39
AKO66_11005	ENOG4108CHM	Preferentially cleaves peptide bonds on the carboxyl- terminal side of aspartate and glutamate. Along with other extracellular proteases it is involved in colonization and infection of human tissues. Required for proteolytic maturation of thiol protease SspB and inactivation of SspC, an inhibitor of SspB. It is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A, which are involved in adherence to host cells. May also protect bacteria against host defense mechanism by cleaving the immunoglobulin classes IgG, IgA and IgM. May be involved in the stability of secreted lipases
AKO66_11010	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AKO66_11015	ENOG41082JN	Transcriptional regulator
AKO66_11020	ENOG4108QY0	Membrane
AKO66_11040	ENOG41080R8	Conserved Protein
AKO66_11045	ENOG4107QR9	Iron-sulfur cluster binding protein
AKO66_11050	ENOG4107R5T	Cysteine-rich domain
AKO66_11060	ENOG4105ECR	NmrA family
AKO66_11065	ENOG4108Z40	Transcriptional regulator
AKO66_11075	ENOG4105NRR	Uncharacterized protein conserved in bacteria (DUF2188)
AKO66_11080	ENOG4105FDF	Could be involved in DNA repair (By similarity)
AKO66_11085	ENOG4105DQE	DNA ligase
AKO66_11090	ENOG4105XPP	Protein of unknown function (DUF1275)
AKO66_11100	ENOG410780I	phosphoprotein phosphatase activity
AKO66_11125	ENOG4108ZMX	Domain of unknown function (DU1801)
AKO66_11185	ENOG410780I	phosphoprotein phosphatase activity
AKO66_11220	ENOG4105C5F	glutamine synthetase
AKO66_11225	ENOG4105KV4	Transcriptional regulator
AKO66_11230	ENOG4105CXI	aluminum resistance protein
AKO66_11235	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AKO66_11240	ENOG4106F1P	AAA ATPase, central domain protein
AKO66_11250	ENOG4105U6W	MutT NUDIX family protein
AKO66_11255	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AKO66_11260	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AKO66_11265	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
AKO66_11285	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AKO66_11310	ENOG410814C	multidrug resistance protein
AKO66_11315	ENOG4108X3M	OsmC Ohr family protein
AKO66_11320	ENOG4105K7W	phage-related replication protein
AKO66_11325	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AKO66_11335	ENOG4105K7W	phage-related replication protein
AKO66_11340	ENOG4108VJ1	Transcriptional regulator (CarD family
AKO66_11360	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AKO66_11365	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AKO66_11380	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AKO66_11390	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AKO66_11395	ENOG4105CPQ	Dehydrogenase
AKO66_11405	ENOG4105MCT	stage V sporulation protein S
AKO66_11410	ENOG4105D48	metallophosphoesterase
AKO66_11415	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
AKO66_11420	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AKO66_11425	ENOG4105CEV	competence damage-inducible protein
AKO66_11430	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AKO66_11445	ENOG4105XZV	Protein of unknown function (DUF3243)
AKO66_11450	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
AKO66_11455	ENOG4105EYF	MMPL domain protein
AKO66_11475	ENOG4105EYF	MMPL domain protein
AKO66_11485	ENOG4105FDP	GntR family transcriptional regulator
AKO66_11490	ENOG4105CNU	cell division protein FtsK
AKO66_11500	ENOG4105CVQ	ATP-dependent Clp protease, proteolytic subunit
AKO66_11510	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AKO66_11520	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AKO66_11525	ENOG4108S0H	Dipicolinic acid synthetase, b subunit
AKO66_11530	ENOG4105E35	Dipicolinate synthase subunit A
AKO66_11540	ENOG4105CAQ	asparagine synthetase
AKO66_11585	ENOG4105CZA	synthase
AKO66_11590	ENOG4107RVV	histidinol phosphate phosphatase, hisj family
AKO66_11595	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AKO66_11600	ENOG4105DTD	Dehydrogenase
AKO66_11620	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
AKO66_11660	ENOG4105BZ1	(ABC) transporter
AKO66_11675	ENOG4105C1V	Peptidase, M16
AKO66_11685	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AKO66_11690	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AKO66_11695	ENOG4105DTN	riboflavin biosynthesis protein ribF
AKO66_11700	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AKO66_11705	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AKO66_11710	ENOG4105W7A	Protein of unknown function (DUF503)
AKO66_11715	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AKO66_11720	ENOG4105VHM	ribosomal protein
AKO66_11725	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
AKO66_11730	ENOG4105CHV	Transcription elongation factor NusA
AKO66_11735	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AKO66_11745	ENOG4105WJF	
AKO66_11750	ENOG4105CYP	glycoside hydrolase, family
AKO66_11760	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
AKO66_11765	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AKO66_11770	ENOG4105DZP	Membrane-associated zinc metalloprotease
AKO66_11775	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
AKO66_11780	ENOG4105KNE	Phosphatidate cytidylyltransferase
AKO66_11785	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AKO66_11790	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AKO66_11800	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AKO66_11805	ENOG4105CE9	30S ribosomal protein S2
AKO66_11815	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AKO66_11820	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
AKO66_11830	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
AKO66_11835	ENOG4105CBS	Chea signal transduction histidine kinase
AKO66_11840	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AKO66_11850	ENOG4105FZW	flagellar biosynthesis regulator FlhF
AKO66_11855	ENOG4105D7B	Flagellar biosynthesis protein flha
AKO66_11860	ENOG4105D00	flagellar biosynthetic protein flhB
AKO66_11865	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
AKO66_11870	ENOG4105VS8	Flagellar biosynthetic protein fliq
AKO66_11875	ENOG4105CN7	Flagellar biosynthetic protein FliP
AKO66_11885	ENOG4107YTP	response regulator receiver protein
AKO66_11890	ENOG4105DD5	Flagellar motor switch protein
AKO66_11895	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AKO66_11905	ENOG41068WV	flagellar FlbD family protein
AKO66_11910	ENOG4108JQA	flagellar
AKO66_11915	ENOG410822I	Flagellar hook capping protein
AKO66_11930	ENOG4106YF4	Flagellar biosynthesis chaperone
AKO66_11945	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AKO66_11950	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
AKO66_11955	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
AKO66_11960	ENOG4108ZC9	flagellar basal-body rod protein flgc
AKO66_11965	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
AKO66_11975	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
AKO66_11980	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
AKO66_11985	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AKO66_11990	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
AKO66_11995	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AKO66_12000	ENOG4105C79	DNA protecting protein DprA
AKO66_12005	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AKO66_12010	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AKO66_12015	ENOG4105VM1	flagellar
AKO66_12025	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AKO66_12030	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
AKO66_12035	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AKO66_12040	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AKO66_12045	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AKO66_12055	ENOG4108BW8	UPF0109 protein
AKO66_12060	ENOG4105K5M	30s ribosomal protein S16
AKO66_12070	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
AKO66_12075	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AKO66_12080	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
AKO66_12085	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AKO66_12090	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AKO66_12095	ENOG4105CHR	reductase
AKO66_12100	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AKO66_12105	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
AKO66_12110	ENOG4108VVV	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity)
AKO66_12115	ENOG4105CB5	ATP-dependent DNA helicase recG
AKO66_12120	ENOG4105EJQ	L-serine dehydratase
AKO66_12130	ENOG4105DP4	dak2 domain fusion protein ylov
AKO66_12135	ENOG4108ZAA	Alkaline-shock protein
AKO66_12140	ENOG4105VB9	50S ribosomal protein l28
AKO66_12150	ENOG4105FJ0	thiamine
AKO66_12155	ENOG4105DJV	ribulose-phosphate 3-epimerase
AKO66_12160	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AKO66_12165	ENOG4105D9P	serine threonine protein kinase
AKO66_12170	ENOG4108ZF3	Phosphatase
AKO66_12175	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AKO66_12180	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AKO66_12185	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AKO66_12190	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AKO66_12195	ENOG4105C25	Primosomal protein n'
AKO66_12200	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AKO66_12210	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AKO66_12215	ENOG4105KC4	UPF0296 protein
AKO66_12220	ENOG4105DSJ	YicC domain protein
AKO66_12230	ENOG4105F23	Fibronectin-binding protein
AKO66_12235	ENOG41087GM	Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein
AKO66_12240	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
AKO66_12245	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AKO66_12250	ENOG4108WF4	Catalyzes the synthesis of activated sulfate (By similarity)
AKO66_12255	ENOG4107RIQ	Sulfate adenylate transferase
AKO66_12265	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
AKO66_12270	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AKO66_12275	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AKO66_12280	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
AKO66_12285	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
AKO66_12290	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AKO66_12295	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AKO66_12300	ENOG4105CD3	dihydroorotase
AKO66_12305	ENOG4105CXT	aspartate transcarbamylase
AKO66_12315	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
AKO66_12320	ENOG4105C34	Pseudouridine synthase
AKO66_12325	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AKO66_12335	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AKO66_12345	ENOG4105DBK	s4 domain protein
AKO66_12350	ENOG41067XK	integral membrane protein
AKO66_12355	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
AKO66_12360	ENOG4105DFA	alanine racemase domain protein
AKO66_12365	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
AKO66_12370	ENOG4105WR5	sporulation protein, YlmC YmxH family
AKO66_12375	ENOG4105DKW	ABC transporter
AKO66_12380	ENOG4105VI0	Pts system, glucitol sorbitol-specific
AKO66_12385	ENOG4105DZY	Pts system, glucitol sorbitol-specific
AKO66_12390	ENOG410787A	Pts system, glucitol sorbitol-specific
AKO66_12405	ENOG4105DKT	Transcriptional regulator
AKO66_12415	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AKO66_12420	ENOG4105FFI	sigma-e processing peptidase spoiiga
AKO66_12430	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AKO66_12435	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AKO66_12440	ENOG4105K67	small basic protein
AKO66_12450	ENOG4108R2U	division initiation protein
AKO66_12455	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
AKO66_12460	ENOG4105D4A	Cell wall formation (By similarity)
AKO66_12465	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AKO66_12470	ENOG4105CNI	cell division protein FtsW
AKO66_12475	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AKO66_12480	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AKO66_12485	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AKO66_12490	ENOG4105CJN	penicillin-binding protein
AKO66_12495	ENOG4105CJN	penicillin-binding protein
AKO66_12505	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AKO66_12510	ENOG4108V6E	Cell division protein mraZ
AKO66_12535	ENOG41067VY	50S ribosomal protein L32
AKO66_12540	ENOG4105KNH	Nucleic acid-binding protein
AKO66_12545	ENOG4105CDE	UPF0348 protein
AKO66_12550	ENOG41063PX	domain protein
AKO66_12555	ENOG4105D78	K07001 NTE family protein
AKO66_12560	ENOG4105H20	Sporulation integral membrane protein YlbJ
AKO66_12565	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AKO66_12570	ENOG4106H78	methyltransferase
AKO66_12575	ENOG4105WUC	UPF0298 protein
AKO66_12600	ENOG4106UY4	Inherit from COG: Scp-like extracellular
AKO66_12605	ENOG41080XQ	Signal transduction protein with cbs domains
AKO66_12620	ENOG41064X9	cytochrome C oxidase subunit IV
AKO66_12625	ENOG4105CCU	oxidase (Subunit III)
AKO66_12630	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AKO66_12640	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AKO66_12650	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AKO66_12655	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
AKO66_12660	ENOG4105CNI	cell division protein FtsW
AKO66_12670	ENOG4105CSV	Glutaminase
AKO66_12680	ENOG4108IAB	Phoh family
AKO66_12695	ENOG4105QA2	
AKO66_12700	ENOG4105CI3	gtp-binding protein typa
AKO66_12730	ENOG4105ECY	inositol monophosphatase
AKO66_12740	ENOG4108WQ8	UPF0637 protein
AKO66_12750	ENOG4105CXN	decarboxylase
AKO66_12760	ENOG4107QN2	dihydrolipoyl dehydrogenase
AKO66_12765	ENOG4105C7S	Dehydrogenase
AKO66_12770	ENOG4105CPP	Dehydrogenase, E1 component
AKO66_12790	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AKO66_12795	ENOG4108X4Q	Hydrolase
AKO66_12805	ENOG4105CN5	Metallo-Beta-Lactamase
AKO66_12810	ENOG4105CPN	adenine deaminase
AKO66_12815	ENOG4107ZYR	domain protein
AKO66_12825	ENOG4105BZU	Histidine kinase
AKO66_12850	ENOG4105C5H	ABC transporter
AKO66_12865	ENOG4105DM4	PTS System
AKO66_12870	ENOG4105DE4	1-phosphofructokinase
AKO66_12875	ENOG4105E98	transcriptional regulator DeoR family
AKO66_12880	ENOG4107RBB	ABC transporter, permease
AKO66_12885	ENOG4105C19	ABC transporter
AKO66_12890	ENOG4107X8C	Efflux transporter RND family MFP subunit
AKO66_12905	ENOG41067WU	Molybdopterin converting factor (Subunit 1)
AKO66_12910	ENOG4108ZAF	Molybdopterin
AKO66_12915	ENOG4108129	molybdopterin-guanine dinucleotide biosynthesis protein
AKO66_12920	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AKO66_12925	ENOG4105D06	uba thif-type nad fad binding protein
AKO66_12930	ENOG41080QG	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AKO66_12945	ENOG4107R19	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AKO66_12950	ENOG4105D3R	alkyl hydroperoxide reductase
AKO66_12955	ENOG4105D8X	mechanosensitive ion channel
AKO66_12960	ENOG4106AUC	UPF0180 protein
AKO66_12970	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
AKO66_12975	ENOG4105NQC	Flavodoxin
AKO66_13010	ENOG4108XRC	Protein of unknown function (DUF458) 
AKO66_13015	ENOG4107IN1	Protein of unknown function (DUF1797)
AKO66_13020	ENOG4105WEF	catalase
AKO66_13025	ENOG4105EPM	Diguanylate phosphodiesterase
AKO66_13030	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
AKO66_13040	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
AKO66_13060	ENOG4105UIN	
AKO66_13065	ENOG4107R88	Chemotaxis protein (CheV)
AKO66_13075	ENOG41085PJ	rdd domain containing protein
AKO66_13085	ENOG4105CHM	Aminotransferase
AKO66_13090	ENOG4105BZU	Histidine kinase
AKO66_13100	ENOG4105K4I	Scp-like extracellular
AKO66_13105	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AKO66_13110	ENOG4105CHR	reductase
AKO66_13115	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
AKO66_13120	ENOG4105F6S	Spore photoproduct lyase
AKO66_13130	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AKO66_13135	ENOG4105KRI	phosphocarrier protein (HPr
AKO66_13145	ENOG4105CID	antiterminator
AKO66_13155	ENOG4105DC7	peptidase M24
AKO66_13160	ENOG4105C59	p-type ATPase
AKO66_13175	ENOG4105F0V	Cell wall hydrolase
AKO66_13195	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
AKO66_13200	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AKO66_13205	ENOG4107ZAE	6-carboxy-5,6,7,8-tetrahydropterin synthase
AKO66_13210	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AKO66_13215	ENOG4108K88	Membrane
AKO66_13225	ENOG4105E14	MotA TolQ exbB proton channel
AKO66_13230	ENOG4105ER2	Ompa motb domain protein
AKO66_13235	ENOG41090MY	MarR family Transcriptional regulator
AKO66_13240	ENOG4105BZU	Histidine kinase
AKO66_13250	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
AKO66_13255	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
AKO66_13260	ENOG4105JAS	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity)
AKO66_13265	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
AKO66_13275	ENOG4105CT5	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity)
AKO66_13280	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
AKO66_13285	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AKO66_13290	ENOG4105BZU	Histidine kinase
AKO66_13295	ENOG4108TGC	Acyltransferase
AKO66_13305	ENOG410900G	Protein of unknown function (DUF421)
AKO66_13315	ENOG4105D0M	Protease HtpX homolog
AKO66_13325	ENOG410681C	small acid-soluble spore protein
AKO66_13335	ENOG4108WZW	RNA polymerase sigma
AKO66_13340	ENOG4107TS3	membrane protein, TerC
AKO66_13345	ENOG4107T5V	SNARE associated Golgi
AKO66_13350	ENOG4105BZU	Histidine kinase
AKO66_13365	ENOG4105V75	Transcriptional regulator
AKO66_13385	ENOG4105CJW	magnesium transporter
AKO66_13395	ENOG4106849	propeptide, pepSY amd peptidase M4
AKO66_13405	ENOG41062D9	Histidine kinase
AKO66_13410	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AKO66_13425	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AKO66_13430	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
AKO66_13435	ENOG4107Y2X	deaminase
AKO66_13440	ENOG4108ZHJ	Organic hydroperoxide resistance protein
AKO66_13445	ENOG4105K56	Transcriptional regulator
AKO66_13465	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AKO66_13470	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AKO66_13475	ENOG4105CIY	formyltetrahydrofolate deformylase
AKO66_13485	ENOG41080TC	multidrug resistance protein
AKO66_13490	ENOG410839T	multidrug resistance protein
AKO66_13495	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AKO66_13500	ENOG4108428	Inherit from COG: -acetyltransferase
AKO66_13515	ENOG4105K7K	Transcriptional regulator
AKO66_13520	ENOG4108S4H	thioesterase Superfamily protein
AKO66_13525	ENOG4107TUM	Amidinotransferase
AKO66_13530	ENOG4108JQ7	(ABC) transporter
AKO66_13535	ENOG4107SN7	NLP P60 protein
AKO66_13540	ENOG4105DTQ	mandelate racemase muconate lactonizing
AKO66_13545	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
AKO66_13555	ENOG4105C3U	ABC transporter
AKO66_13560	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AKO66_13565	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AKO66_13570	ENOG4108ME1	Peptidase M55 D-aminopeptidase
AKO66_13580	ENOG4105C0H	protease
AKO66_13590	ENOG4107R7I	amino acid
AKO66_13600	ENOG4107RHR	regulatoR
AKO66_13605	ENOG4105CHR	reductase
AKO66_13610	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AKO66_13620	ENOG4107QKR	Dehydrogenase
AKO66_13625	ENOG4105CPP	Dehydrogenase, E1 component
AKO66_13630	ENOG4107RUY	(E1 component), alpha subunit
AKO66_13650	ENOG4105DT3	PTS system, galactitol-specific IIc component
AKO66_13665	ENOG4105ECW	sulfate abc transporter
AKO66_13670	ENOG4108I5D	sulfate abc transporter
AKO66_13675	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
AKO66_13680	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AKO66_13690	ENOG4107GRR	phosphate transport regulator
AKO66_13695	ENOG4105CJ3	phosphate transporter
AKO66_13710	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
AKO66_13720	ENOG410635T	phage-like element pbsx protein
AKO66_13725	ENOG4105K7W	phage-related replication protein
AKO66_13745	ENOG4105I03	Flagellin
AKO66_13750	ENOG4105I03	Flagellin
AKO66_13755	ENOG4105I03	Flagellin
AKO66_13760	ENOG4105I03	Flagellin
AKO66_13770	ENOG4105PF9	Transcriptional regulator
AKO66_13780	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AKO66_13815	ENOG4105DJ2	Major Facilitator Superfamily
AKO66_13820	ENOG4107V2S	Transcriptional regulator
AKO66_13840	ENOG4105DUM	transcriptional regulator, lysR family
AKO66_13880	ENOG41082BV	acetyltransferase
AKO66_13895	ENOG4107RSM	transcriptional regulator
AKO66_13905	ENOG4105DJ2	Major Facilitator Superfamily
AKO66_13925	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AKO66_13930	ENOG4105D52	delta-aminolevulinic acid dehydratase
AKO66_14065	ENOG4105C28	cystathionine
AKO66_14070	ENOG4105C28	cystathionine
AKO66_14095	ENOG4105ENA	helicase
AKO66_14140	ENOG4107A88	
AKO66_14145	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
AKO66_14150	ENOG4105DWF	phosphomethylpyrimidine kinase
AKO66_14155	ENOG4105D06	uba thif-type nad fad binding protein
AKO66_14160	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AKO66_14175	ENOG4108VEU	Thiamine monophosphate synthase
AKO66_14180	ENOG4105ETU	transcriptional activator (TenA
AKO66_14190	ENOG4107S1Q	Phosphatase
AKO66_14195	ENOG4105EMS	pseudouridine synthase
AKO66_14200	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AKO66_14210	ENOG4106EFP	UPF0738 protein
AKO66_14215	ENOG4105MIX	Adenylate cyclase
AKO66_14220	ENOG4105E4C	Lytic transglycosylase catalytic
AKO66_14225	ENOG4108Z18	K06886 hemoglobin
AKO66_14230	ENOG4105T58	Dithiol-disulfide isomerase
AKO66_14235	ENOG4105DPN	Oligoendopeptidase f
AKO66_14245	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AKO66_14250	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
AKO66_14255	ENOG4108ZCF	integral membrane protein
AKO66_14260	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
AKO66_14275	ENOG4108JQ7	(ABC) transporter
AKO66_14285	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AKO66_14290	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AKO66_14295	ENOG4108J59	Extracellular solute-binding protein, family 5
AKO66_14300	ENOG4105C31	Tryptophanyl-tRNA synthetase
AKO66_14310	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AKO66_14325	ENOG4108JQ7	(ABC) transporter
AKO66_14330	ENOG4105C3U	ABC transporter
AKO66_14340	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AKO66_14345	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AKO66_14360	ENOG4107RMD	Basic membrane lipoprotein
AKO66_14390	ENOG4105DBV	ornithine carbamoyltransferase
AKO66_14400	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AKO66_14405	ENOG4105C8Y	Acetylornithine aminotransferase
AKO66_14410	ENOG4105CAS	nag kinase
AKO66_14420	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AKO66_14430	ENOG4105IQ5	FAD linked oxidase domain protein
AKO66_14435	ENOG4105VG1	fes assembly suf system protein
AKO66_14440	ENOG4108MXZ	Esterase
AKO66_14445	ENOG4108KP7	hydrolase
AKO66_14455	ENOG41073B9	
AKO66_14465	ENOG4107AYK	membrAne
AKO66_14470	ENOG4105EPR	degv family
AKO66_14475	ENOG4105C8Q	Methyl-accepting chemotaxis
AKO66_14480	ENOG4105DIH	basic membrane
AKO66_14485	ENOG4105QNR	S1 RNA binding domain protein
AKO66_14490	ENOG4108VPT	UPF0234 protein
AKO66_14535	ENOG4105DY8	decarboxylase
AKO66_14560	ENOG4106HBX	Transcriptional Regulator AraC Family
AKO66_14565	ENOG4105UQX	Mate efflux family protein
AKO66_14585	ENOG4105CAQ	asparagine synthetase
AKO66_14595	ENOG4106BKT	UPF0344 protein
AKO66_14600	ENOG4105ERH	Fumarylacetoacetate hydrolase
AKO66_14660	ENOG4105EYH	Exonuclease
AKO66_14670	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
AKO66_14700	ENOG4108KK1	membrane protein AbrB duplication
AKO66_14715	ENOG41060YP	
AKO66_14725	ENOG4108KGH	TRANSCRIPTIONal
AKO66_14735	ENOG4108IPW	abc transporter atp-binding protein
AKO66_14740	ENOG4105CM4	permease protein
AKO66_14745	ENOG4105DHS	permease protein
AKO66_14750	ENOG41067XF	inhibitor
AKO66_14755	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AKO66_14760	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AKO66_14775	ENOG4105XVF	Competence transcription factor
AKO66_14795	ENOG4106YBV	Methyl-accepting chemotaxis
AKO66_14800	ENOG4107TB6	phosphoglycerate mutase
AKO66_14810	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
AKO66_14820	ENOG4105CEY	Amp-dependent synthetase and ligase
AKO66_14825	ENOG4105DF9	Lipoate-protein, ligase
AKO66_14830	ENOG4108RQ5	Beta-lactamase domain-containing protein
AKO66_14840	ENOG4105DER	m42 family
AKO66_14845	ENOG4105ECB	domain protein
AKO66_14855	ENOG4105C1Q	protoporphyrinogen oxidase
AKO66_14860	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AKO66_14865	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AKO66_14870	ENOG4105BZ4	penicillin-binding protein
AKO66_14875	ENOG4105Q24	Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation
AKO66_14905	ENOG4105K59	histidine triad (HIT) protein
AKO66_14910	ENOG4105DXJ	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
AKO66_14915	ENOG4105NBU	tryptophan transport protein
AKO66_14950	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
AKO66_14965	ENOG4106D4I	domain protein
AKO66_14970	ENOG4107VRP	DNA repair exonuclease
AKO66_14980	ENOG4105CGU	Enoyl-CoA hydratase
AKO66_14990	ENOG4105NCW	Trka-c domain protein
AKO66_14995	ENOG4107S91	Sodium hydrogen exchanger
AKO66_15005	ENOG4105D4P	Coproporphyrinogen iii oxidase
AKO66_15015	ENOG4105WZB	UPF0342 protein
AKO66_15020	ENOG4108UH6	UPF0754 membrane protein
AKO66_15030	ENOG410839P	
AKO66_15060	ENOG4105BZ1	(ABC) transporter
AKO66_15065	ENOG4105BZ1	(ABC) transporter
AKO66_15075	ENOG4105F0I	Aminotransferase
AKO66_15080	ENOG4107VMI	polysaccharide deacetylase
AKO66_15085	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AKO66_15090	ENOG4105D64	Mechanosensitive ion channel
AKO66_15095	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
AKO66_15100	ENOG4105WMR	Protein CrcB homolog
AKO66_15105	ENOG4106A8V	Protein CrcB homolog
AKO66_15115	ENOG4105C37	(CBS) domain
AKO66_15125	ENOG4105C37	(CBS) domain
AKO66_15130	ENOG4105F6E	Acyl-transferase
AKO66_15135	ENOG4108AEY	RNA polymerase sigma factor
AKO66_15140	ENOG4105J37	
AKO66_15150	ENOG4105CUB	amino acid
AKO66_15160	ENOG4105G6Z	alkaline phosphatase
AKO66_15165	ENOG4105ED1	spovr family
AKO66_15170	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
AKO66_15175	ENOG4105KPV	Transcriptional regulator
AKO66_15180	ENOG4105CH6	catalase
AKO66_15195	ENOG4105WH1	Two component transcriptional regulator luxr family
AKO66_15200	ENOG4105BZU	Histidine kinase
AKO66_15210	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AKO66_15215	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AKO66_15225	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
AKO66_15230	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AKO66_15235	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
AKO66_15255	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
AKO66_15260	ENOG4107YBY	Hydrolase
AKO66_15270	ENOG4108YBP	pseudouridine synthase
AKO66_15285	ENOG4105BZU	Histidine kinase
AKO66_15315	ENOG4105BZU	Histidine kinase
AKO66_15320	ENOG4105VEQ	Cold shock protein
AKO66_15330	ENOG4105CS1	NAD(P)H quinone oxidoreductase
AKO66_15335	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AKO66_15340	ENOG4105CW7	secretion protein, HlyD family
AKO66_15345	ENOG4106AKX	UPF0229 protein
AKO66_15350	ENOG4105CYN	Serine protein kinase
AKO66_15355	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AKO66_15365	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
AKO66_15400	ENOG4105CJ1	ABC, transporter
AKO66_15415	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
AKO66_15420	ENOG4108J8Z	aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein
AKO66_15425	ENOG4105E2Y	ABC, transporter
AKO66_15445	ENOG4105E0M	Sulfatase
AKO66_15600	ENOG4105G5W	regulator Fur family
AKO66_15605	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AKO66_15610	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AKO66_15615	ENOG4107NBY	Membrane
AKO66_15620	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AKO66_15625	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AKO66_15630	ENOG4105DEF	Extracellular solute-binding protein, family 5
AKO66_15635	ENOG4108JQ7	(ABC) transporter
AKO66_15640	ENOG4105C3U	ABC transporter
AKO66_15645	ENOG4105BZ1	(ABC) transporter
AKO66_15650	ENOG4105EVI	UPF0374 protein
AKO66_15665	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
AKO66_15670	ENOG4106BXE	
AKO66_15675	ENOG4105CEN	a g-specific adenine glycosylase
AKO66_15680	ENOG41067AE	Membrane-bound metal-dependent hydrolase
AKO66_15690	ENOG4106DF4	Sigma-70, region 4
AKO66_15695	ENOG4105F0F	Oxalate decarboxylase
AKO66_15710	ENOG4105MSY	salicylate hydroxylase
AKO66_15715	ENOG4105EJV	Membrane
AKO66_15720	ENOG4105CKK	Glycosyl transferase, family 2
AKO66_15740	ENOG4105KC9	Modulates RecA activity (By similarity)
AKO66_15745	ENOG4105ECP	epimerase
AKO66_15755	ENOG4107Y03	Nitroreductase
AKO66_15780	ENOG410834F	Transcriptional regulator
AKO66_15790	ENOG4108YYS	metal-dependent hydrolase (By similarity)
AKO66_15810	ENOG4105K6V	RNA polymerase
AKO66_15815	ENOG4105KK4	UPF0060 membrane protein
AKO66_15820	ENOG4105BZ1	(ABC) transporter
AKO66_15825	ENOG4108HUF	Transporter
AKO66_15840	ENOG4107TDE	lipolytic protein G-D-S-L family
AKO66_15860	ENOG410839T	multidrug resistance protein
AKO66_15920	ENOG4108RWP	Major Facilitator Superfamily protein
AKO66_15925	ENOG4107TXC	Transcriptional regulator
AKO66_15930	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
AKO66_15935	ENOG4105MDS	4-oxalocrotonate tautomerase
AKO66_15940	ENOG4107V2S	Transcriptional regulator
AKO66_15955	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AKO66_15970	ENOG4105D7N	magnesium and cobalt transport protein CorA
AKO66_15995	ENOG4105D8X	mechanosensitive ion channel
AKO66_16005	ENOG4105CDY	transcriptional regulatory protein
AKO66_16015	ENOG4105UPD	Calcium Proton
AKO66_16025	ENOG4108ISG	Major Facilitator
AKO66_16030	ENOG4107U9T	Pfam:Ribonuclease_BN
AKO66_16040	ENOG4105KJF	protein tyrosine phosphatase
AKO66_16045	ENOG4105BZG	amino acid carrier protein
AKO66_16055	ENOG4107RKG	DJ-1/PfpI family
AKO66_16060	ENOG4105CGH	5'-nucleotidase
AKO66_16070	ENOG4107414	GntR family transcriptional regulator
AKO66_16075	ENOG4105CG3	alpha amylase, catalytic region
AKO66_16080	ENOG4105C5Y	PTS System
AKO66_16095	ENOG4105DY8	decarboxylase
AKO66_16115	ENOG4105NX3	Membrane
AKO66_16125	ENOG4106A4F	Removes the N-terminal methionine from nascent proteins (By similarity)
AKO66_16130	ENOG4108RPX	mosc domain containing protein
AKO66_16135	ENOG41084AG	Acylphosphatase
AKO66_16150	ENOG4105U3E	Transcriptional regulator
AKO66_16155	ENOG4105PY6	Phenolic acid decarboxylase
AKO66_16175	ENOG4108MRH	transcriptional regulatory protein
AKO66_16190	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AKO66_16200	ENOG4105E6M	Sulphatase-modifying factor protein
AKO66_16205	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AKO66_16225	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
AKO66_16230	ENOG4105FDU	atp-dependent rna helicase
AKO66_16235	ENOG4105C5H	ABC transporter
AKO66_16240	ENOG4105DXB	Major Facilitator superfamily
AKO66_16245	ENOG4107SWG	transcriptional regulator MERR family
AKO66_16250	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
AKO66_16255	ENOG4105C5H	ABC transporter
AKO66_16260	ENOG4107TVC	Glycosyl transferase, family 2
AKO66_16265	ENOG4105CUB	amino acid
AKO66_16295	ENOG4105C8P	)-transporter
AKO66_16300	ENOG4107RVG	penicillin-binding protein
AKO66_16305	ENOG4105EU0	Major facilitator Superfamily
AKO66_16310	ENOG41090R9	glycosyltransferase
AKO66_16315	ENOG4107R51	Glycosyl transferase, family 2
AKO66_16320	ENOG41090R9	glycosyltransferase
AKO66_16330	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
AKO66_16335	ENOG4108R1P	
AKO66_16360	ENOG4105HX0	Transcriptional regulator
AKO66_16365	ENOG4105F8D	glycoside hydrolase family 4
AKO66_16380	ENOG4105C3M	thioredoxin reductase
AKO66_16385	ENOG41062ES	Transcriptional regulator
AKO66_16405	ENOG4107EV6	Inherit from COG: YD repeat protein
AKO66_16415	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AKO66_16420	ENOG4105CBD	Diacylglycerol kinase
AKO66_16425	ENOG4105DU0	nucleoside hydrolase
AKO66_16435	ENOG4108IG5	Transcriptional regulator
AKO66_16440	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AKO66_16445	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AKO66_16450	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AKO66_16455	ENOG4105CK7	Sodium proline symporter
AKO66_16460	ENOG4105KT7	mgtC SapB transporter
AKO66_16465	ENOG4105CRN	Aminoglycoside phosphotransferase
AKO66_16475	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AKO66_16480	ENOG4105C4R	Atp-dependent dna helicase
AKO66_16485	ENOG4108RTE	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales (By similarity)
AKO66_16500	ENOG4105CBC	glutamate synthase
AKO66_16510	ENOG4105KGF	protein, YerC YecD
AKO66_16525	ENOG4107S4Y	M20 DapE family protein YgeY
AKO66_16540	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AKO66_16560	ENOG4105C12	Phosphoribosylglycinamide synthetase
AKO66_16565	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AKO66_16570	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AKO66_16575	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AKO66_16585	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
AKO66_16595	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
AKO66_16600	ENOG4105C8V	SAICAR synthetase
AKO66_16605	ENOG4105C83	adenylosuccinate lyase
AKO66_16610	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AKO66_16615	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AKO66_16625	ENOG4108U5N	UPF0316 protein
AKO66_16640	ENOG4105C7N	Xanthine uracil vitamin C permease
AKO66_16645	ENOG4105GZI	Transcriptional regulator
AKO66_16650	ENOG4108RWP	Major Facilitator Superfamily protein
AKO66_16660	ENOG4105JVQ	RNA Polymerase
AKO66_16675	ENOG4105KNA	-acetyltransferase
AKO66_16680	ENOG4105DY9	regulatoR
AKO66_16705	ENOG4108DMH	HTH_ARAC
AKO66_16710	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AKO66_16720	ENOG4108UIN	ybak prolyl-trna synthetase associated region
AKO66_16730	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AKO66_16745	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AKO66_16755	ENOG4105C85	amino acid
AKO66_16760	ENOG4107STQ	Multicopper oxidase
AKO66_16800	ENOG4108VXD	carboxy-peptidase
AKO66_16810	ENOG4108U05	Transcriptional regulator
AKO66_16835	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AKO66_16840	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AKO66_16845	ENOG4108TYN	CAAX amino terminal protease family protein
AKO66_16860	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AKO66_16865	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AKO66_16870	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
AKO66_16875	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AKO66_16880	ENOG4105C5H	ABC transporter
AKO66_16885	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AKO66_16890	ENOG410801F	ribosomal-protein-alanine acetyltransferase
AKO66_16895	ENOG41072GX	Peptidase M22 Glycoprotease
AKO66_16900	ENOG4105K8N	protein family UPF0079, ATPase
AKO66_16905	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AKO66_16970	ENOG4108UMN	azlc family
AKO66_16990	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
AKO66_16995	ENOG4108VP3	Lysine exporter protein (LysE YggA)
AKO66_17000	ENOG4108JCI	Transcriptional regulator
AKO66_17015	ENOG4108TVJ	Nitroreductase
AKO66_17020	ENOG41090MY	MarR family Transcriptional regulator
AKO66_17025	ENOG4105NAE	bifunctional deaminase-reductase domain protein
AKO66_17030	ENOG4105ST3	Transcriptional regulator
AKO66_17040	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
AKO66_17045	ENOG4105VDT	-acetyltransferase
AKO66_17095	ENOG4106HB6	Alpha beta hydrolase
AKO66_17100	ENOG4107RB3	L-asparaginase
AKO66_17110	ENOG4107GJV	short-chain dehydrogenase reductase
AKO66_17125	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AKO66_17140	ENOG4105VUF	Transcriptional regulator
AKO66_17145	ENOG4105DQ4	alcohol dehydrogenase
AKO66_17150	ENOG4108VJ1	Transcriptional regulator (CarD family
AKO66_17155	ENOG4105VEQ	Cold shock protein
AKO66_17220	ENOG41064BQ	Phosphatase
AKO66_17230	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
AKO66_17235	ENOG4105WN5	stage II sporulation protein
AKO66_17240	ENOG4107SGM	protein serine threonine phosphatase
AKO66_17245	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
AKO66_17250	ENOG4105FUA	antagonist
AKO66_17255	ENOG4107MMM	Anti-sigma-factor antagonist
AKO66_17260	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
AKO66_17270	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AKO66_17275	ENOG4108SGW	outer membrane lipoprotein-sorting protein-like protein
AKO66_17290	ENOG4105CKV	Membrane
AKO66_17295	ENOG410905X	membrane-flanked domain protein
AKO66_17300	ENOG4105C1J	atp-dependent rna helicase
AKO66_17315	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
AKO66_17320	ENOG4105CPF	Cell wall formation (By similarity)
AKO66_17325	ENOG4105SZ6	Thioredoxin
AKO66_17345	ENOG4105CJ1	ABC, transporter
AKO66_17355	ENOG4106F5Q	Membrane
AKO66_17360	ENOG4107QJT	sodium dicarboxylate symporter
AKO66_17365	ENOG4108MRH	transcriptional regulatory protein
AKO66_17370	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
AKO66_17375	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AKO66_17380	ENOG4105EU9	
AKO66_17385	ENOG4107BMA	Transglycosylase associated protein
AKO66_17390	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
AKO66_17425	ENOG4105C0X	amino acid
AKO66_17435	ENOG4107R8N	Glycosyl transferase, family 2
AKO66_17440	ENOG4105I5R	Uncharacterized protein conserved in bacteria (DUF2334)
AKO66_17455	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AKO66_17460	ENOG4105VCH	membrane
AKO66_17480	ENOG410606W	general stress protein
AKO66_17485	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AKO66_17490	ENOG4105HMZ	Methyltransferase
AKO66_17495	ENOG4105ETD	TRANSCRIPTIONal
AKO66_17505	ENOG4105XJB	lipolytic protein G-D-S-L family
AKO66_17510	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
AKO66_17515	ENOG4107258	Transcriptional regulator
AKO66_17525	ENOG4105P4J	Allophanate hydrolase, subunit 1
AKO66_17530	ENOG4105CFM	UPF0317 protein
AKO66_17535	ENOG4105C5A	transporter
AKO66_17540	ENOG4105E7W	lamb ycsf family protein
AKO66_17565	ENOG4105X3H	Excalibur domain protein
AKO66_17605	ENOG4105C8Q	Methyl-accepting chemotaxis
AKO66_17610	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
AKO66_17625	ENOG4108T5E	Copper resistance protein
AKO66_17630	ENOG4105KTB	nuclear export factor GLE1
AKO66_17635	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
AKO66_17640	ENOG4105C26	Dehydrogenase
AKO66_17645	ENOG4107QTZ	amino acid
AKO66_17650	ENOG4108JPW	Aminotransferase
AKO66_17660	ENOG4105EGI	Transcriptional regulator
AKO66_17670	ENOG4105YVS	arsR family transcriptional regulator
AKO66_17680	ENOG4105R8C	Transcriptional regulator
AKO66_17690	ENOG4105CFH	Aspartokinase
AKO66_17700	ENOG4105BZU	Histidine kinase
AKO66_17705	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AKO66_17720	ENOG4108PGP	mmge prpd family protein
AKO66_17725	ENOG4105CH2	amidohydrolase
AKO66_17735	ENOG4108HW4	amino acid AbC transporter
AKO66_17740	ENOG4105EAB	amino acid AbC transporter
AKO66_17745	ENOG4108XSB	acetyltransferase, (GNAT) family
AKO66_17750	ENOG4105CPU	Monooxygenase
AKO66_17760	ENOG4105DUX	Transporter
AKO66_17765	ENOG4108IQI	permease
AKO66_17775	ENOG4105DRP	amino acid AbC transporter
AKO66_17780	ENOG4105CDA	abc transporter atp-binding protein
AKO66_17800	ENOG4105SX7	Transporter
AKO66_17830	ENOG4105CEY	Amp-dependent synthetase and ligase
AKO66_17840	ENOG4105F38	ABC transporter, permease
AKO66_17845	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AKO66_17875	ENOG4105C8Q	Methyl-accepting chemotaxis
AKO66_17885	ENOG4108AQF	aminoglycoside N(3)-acetyltransferase
AKO66_17895	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
AKO66_17905	ENOG4107XKZ	Amino acid ABC superfamily ATP binding cassette transporter binding protein
AKO66_17910	ENOG4105E5Q	amino acid AbC transporter
AKO66_17915	ENOG4107R5R	arsenical pump membrane protein
AKO66_17920	ENOG4107YHD	transcriptional regulator
AKO66_17925	ENOG4105C26	Dehydrogenase
AKO66_17935	ENOG410756H	nucleotidyltransferase
AKO66_17945	ENOG4105I82	acetyl xylan esterase
AKO66_17950	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
AKO66_17955	ENOG4105C5Q	Transcriptional regulator
AKO66_17960	ENOG41089UC	methyltransferase, type 11
AKO66_17965	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AKO66_17970	ENOG4108N16	Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region
AKO66_17980	ENOG4105DJB	Major Facilitator Superfamily
AKO66_17985	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
AKO66_17995	ENOG4105C7K	acetolactate synthase
AKO66_18000	ENOG4105FF2	Type I DHQase
AKO66_18015	ENOG4107RMH	nh(3)-dependent nad( ) synthetase
AKO66_18020	ENOG4105EIG	urea carboxylase-associated protein 1
AKO66_18060	ENOG4105TRI	Hydrolase
AKO66_18080	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AKO66_18110	ENOG4107SQ8	Glycine betaine
AKO66_18115	ENOG4108IJ7	Glycine betaine
AKO66_18125	ENOG4108TTB	tellurium resistance protein
AKO66_18150	ENOG4107TS3	membrane protein, TerC
AKO66_18155	ENOG4106FN3	tellurium resistance protein
AKO66_18160	ENOG4106FN3	tellurium resistance protein
AKO66_18165	ENOG4108N0M	stress protein
AKO66_18170	ENOG4105DEN	Luciferase family
AKO66_18180	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
AKO66_18200	ENOG4108SDH	ABC, transporter
AKO66_18205	ENOG4108IUW	ABC transporter
AKO66_18210	ENOG4107Y7X	LytTR
AKO66_18220	ENOG4107SET	aldo keto reductase
AKO66_18230	ENOG4105BZU	Histidine kinase
AKO66_18235	ENOG4105WH1	Two component transcriptional regulator luxr family
AKO66_18245	ENOG41060AI	SEC-C motif
AKO66_18260	ENOG4105CSV	Glutaminase
AKO66_18270	ENOG4105D74	hydrolase
AKO66_18280	ENOG4105CUB	amino acid
AKO66_18290	ENOG41067TZ	transcriptional regulator, MarR family
AKO66_18295	ENOG4105E2A	Dehydrogenase
AKO66_18305	ENOG4105J7D	transcriptional regulator
AKO66_18315	ENOG4105J8Z	peptidase S8 and S53, subtilisin, kexin, sedolisin
AKO66_18335	ENOG4105C2C	drug resistance transporter, Bcr CflA
AKO66_18350	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
AKO66_18355	ENOG4108J5H	Homocysteine s-methyltransferase
AKO66_18360	ENOG4108IQI	permease
AKO66_18370	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AKO66_18380	ENOG4108YRF	PTS System
AKO66_18385	ENOG4105DM4	PTS System
AKO66_18390	ENOG4105C8I	hydrolase, family 38
AKO66_18395	ENOG4105EVU	fructokinase
AKO66_18400	ENOG4105EMD	TRANSCRIPTIONal
AKO66_18415	ENOG4105CS2	ec 3.2.1.21
AKO66_18420	ENOG4105C5Y	PTS System
AKO66_18425	ENOG4105CID	antiterminator
AKO66_18435	ENOG4107QTZ	amino acid
AKO66_18440	ENOG4105C72	UPF0176 protein
AKO66_18445	ENOG4107SCQ	Iron-containing alcohol dehydrogenase
AKO66_18460	ENOG4105EWC	Purine nucleoside phosphorylase
AKO66_18485	ENOG4108SUT	Major Facilitator Superfamily
AKO66_18490	ENOG4107R1M	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity)
AKO66_18495	ENOG41087NI	Sulfite exporter TauE/SafE
AKO66_18500	ENOG4105VFE	sira family
AKO66_18505	ENOG4107TPS	domain protein
AKO66_18510	ENOG4105VFE	sira family
AKO66_18520	ENOG4105HF9	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
AKO66_18525	ENOG4105XTG	Pfam:DUF156
AKO66_18540	ENOG4105WAB	arsR family transcriptional regulator
AKO66_18550	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AKO66_18555	ENOG4105C7Z	Conserved Protein
AKO66_18565	ENOG4105CXY	transporter
AKO66_18570	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
AKO66_18590	ENOG4105YA8	Transcriptional regulator
AKO66_18600	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
AKO66_18610	ENOG4105VZ8	Transcriptional regulator
AKO66_18655	ENOG4108WUZ	(ABC) transporter
AKO66_18660	ENOG41066N6	Abortive infection protein
AKO66_18665	ENOG4107ZBH	radical SAM domain protein
AKO66_18680	ENOG4105U3E	Transcriptional regulator
AKO66_18685	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AKO66_18690	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AKO66_18700	ENOG4105DA5	(ABC) transporter
AKO66_18720	ENOG4105CUX	Signal transduction histidine kinase
AKO66_18725	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AKO66_18730	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AKO66_18735	ENOG4107U5W	ybbr family
AKO66_18740	ENOG4105C8B	TIGR00159 family
AKO66_18750	ENOG4105EMN	RNA polymerase sigma factor
AKO66_18785	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AKO66_18805	ENOG4105D17	glycoside hydrolase, family 3 domain protein
AKO66_18810	ENOG4105EHZ	conserved protein UCP016719
AKO66_18820	ENOG4105CHH	sulfate transporter
AKO66_18825	ENOG4105I03	Flagellin
AKO66_18865	ENOG4108NMV	polysaccharide deacetylase
AKO66_18880	ENOG4105D1F	ATP-binding protein
AKO66_18915	ENOG4108UJD	30S ribosomal protein S9
AKO66_18920	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AKO66_18925	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AKO66_18930	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
AKO66_18935	ENOG4108JJB	ABC transporter
AKO66_18940	ENOG4108JJB	ABC transporter
AKO66_18945	ENOG4108ZT0	50S ribosomal protein l17
AKO66_18950	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AKO66_18955	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AKO66_18960	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AKO66_18970	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AKO66_18975	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AKO66_18980	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AKO66_18985	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AKO66_18990	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AKO66_18995	ENOG4105VPB	50S ribosomal protein L30
AKO66_19000	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AKO66_19005	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AKO66_19010	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AKO66_19015	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AKO66_19020	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AKO66_19025	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AKO66_19030	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AKO66_19035	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AKO66_19040	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AKO66_19045	ENOG41082SA	50s ribosomal protein l29
AKO66_19050	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AKO66_19055	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AKO66_19060	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AKO66_19065	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AKO66_19070	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AKO66_19075	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AKO66_19080	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AKO66_19085	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AKO66_19090	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AKO66_19095	ENOG4107SKW	Inherit from COG: Alpha beta hydrolase
AKO66_19105	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AKO66_19110	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AKO66_19115	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AKO66_19120	ENOG4105XPM	ribosomal protein
AKO66_19125	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AKO66_19130	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AKO66_19135	ENOG4107Y49	methyltransferase
AKO66_19140	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AKO66_19145	ENOG4108VZM	50s ribosomal protein L10
AKO66_19150	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AKO66_19155	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AKO66_19160	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AKO66_19175	ENOG4105M0M	Tetracycline resistance protein
AKO66_19180	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AKO66_19185	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AKO66_19190	ENOG4105C8N	cysteinyl-tRNA synthetase
AKO66_19195	ENOG4105D7W	serine acetyltransferase
AKO66_19200	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AKO66_19205	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AKO66_19210	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
AKO66_19215	ENOG4105CTP	PilT protein domain protein
AKO66_19220	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
AKO66_19225	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AKO66_19235	ENOG41066A3	ATP guanido phosphotransferase
AKO66_19240	ENOG4108Z0C	Uvrb UvrC protein