locus-tag	class	description
EQK04_00020	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
EQK04_00025	COG3853	Toxic anion resistance protein (TelA)
EQK04_00030	COG1982	Orn Lys Arg decarboxylase major
EQK04_00035	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EQK04_00040	COG3870	Protein conserved in bacteria
EQK04_00045	COG1728	Protein conserved in bacteria
EQK04_00050	COG0470	DNA polymerase III
EQK04_00055	COG1774	PSP1 C-terminal conserved region
EQK04_00060	COG4467	Involved in initiation control of chromosome replication
EQK04_00065	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EQK04_00070	COG2827	Endonuclease containing a URI domain
EQK04_00075	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EQK04_00080	COG2002	toxin-antitoxin pair type II binding
EQK04_00090	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQK04_00090	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQK04_00095	COG0084	hydrolase, TatD family'
EQK04_00100	COG3583	domain protein
EQK04_00100	COG3584	3D domain protein
EQK04_00105	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EQK04_00110	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EQK04_00120	COG4466	Protein conserved in bacteria
EQK04_00130	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EQK04_00135	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EQK04_00140	COG0251	oxidation-reduction process
EQK04_00145	COG2088	sporulation resulting in formation of a cellular spore
EQK04_00155	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EQK04_00160	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EQK04_00165	COG0193	aminoacyl-tRNA hydrolase activity
EQK04_00175	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EQK04_00180	COG2002	toxin-antitoxin pair type II binding
EQK04_00185	COG2244	polysaccharide biosynthetic process
EQK04_00190	COG3956	TIGRFAM MazG family protein
EQK04_00195	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EQK04_00210	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EQK04_00215	COG1098	S1 RNA binding domain
EQK04_00230	COG2208	phosphoserine phosphatase activity
EQK04_00235	COG2304	oxidoreductase activity
EQK04_00240	COG0515	serine threonine protein kinase
EQK04_00245	COG0037	tRNA processing
EQK04_00255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EQK04_00260	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EQK04_00265	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EQK04_00270	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EQK04_00275	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EQK04_00280	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EQK04_00285	COG0512	Glutamine amidotransferase of anthranilate synthase
EQK04_00290	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EQK04_00295	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EQK04_00300	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EQK04_00305	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EQK04_00310	COG1396	sequence-specific DNA binding
EQK04_00315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EQK04_00320	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EQK04_00400	COG4463	regulation of RNA biosynthetic process
EQK04_00405	COG3880	PFAM UvrB UvrC protein
EQK04_00410	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EQK04_00415	COG0542	response to heat
EQK04_00420	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EQK04_00425	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EQK04_00430	COG4956	integral membrane protein (PIN domain superfamily)
EQK04_00435	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EQK04_00440	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EQK04_00445	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EQK04_00450	COG1045	serine acetyltransferase
EQK04_00455	COG0215	cysteine-tRNA ligase activity
EQK04_00460	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EQK04_00465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EQK04_00470	COG3688	RNA-binding protein containing a PIN domain
EQK04_00475	COG1595	DNA-templated transcription, initiation
EQK04_00480	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EQK04_00485	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EQK04_00490	COG0250	Participates in transcription elongation, termination and antitermination
EQK04_00500	COG0081	regulation of translation
EQK04_00505	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EQK04_00510	COG0222	ribosome binding
EQK04_00515	COG2813	Specifically methylates the guanine in position
EQK04_00520	COG0085	RNA polymerase activity
EQK04_00525	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EQK04_00530	COG1358	cellular component organization or biogenesis
EQK04_00535	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EQK04_00540	COG0049	tRNA binding
EQK04_00545	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EQK04_00550	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EQK04_00555	COG0596	Alpha beta hydrolase
EQK04_00565	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EQK04_00570	COG0088	Forms part of the polypeptide exit tunnel
EQK04_00575	COG0089	rRNA binding
EQK04_00580	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EQK04_00585	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EQK04_00590	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EQK04_00595	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EQK04_00600	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EQK04_00605	COG0255	Belongs to the universal ribosomal protein uL29 family
EQK04_00610	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EQK04_00615	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EQK04_00620	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EQK04_00625	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EQK04_00630	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EQK04_00635	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EQK04_00640	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EQK04_00645	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EQK04_00650	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EQK04_00655	COG1841	ribosomal large subunit assembly
EQK04_00660	COG0200	Binds to the 23S rRNA
EQK04_00665	COG0201	protein transport
EQK04_00670	COG0563	adenylate kinase activity
EQK04_00675	COG0024	Methionine aminopeptidase
EQK04_00685	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EQK04_00690	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EQK04_00695	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EQK04_00700	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EQK04_00705	COG0202	RNA polymerase activity
EQK04_00710	COG0203	ribosomal protein L17
EQK04_00715	COG1122	ATPase activity
EQK04_00720	COG1122	ATPase activity
EQK04_00725	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EQK04_00730	COG0101	tRNA pseudouridine synthase activity
EQK04_00735	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EQK04_00740	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EQK04_00745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EQK04_00770	COG1136	(ABC) transporter
EQK04_00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
EQK04_00795	COG0489	protein tyrosine kinase activity
EQK04_00805	COG2194	sulfuric ester hydrolase activity
EQK04_00810	COG0726	polysaccharide deacetylase
EQK04_00840	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EQK04_00845	COG0659	secondary active sulfate transmembrane transporter activity
EQK04_00850	COG0385	Bile acid
EQK04_00855	COG3876	Protein conserved in bacteria
EQK04_00860	COG1472	Belongs to the glycosyl hydrolase 3 family
EQK04_00865	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EQK04_00870	COG1263	PTS System
EQK04_00870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQK04_00875	COG1737	Transcriptional regulator
EQK04_00880	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EQK04_00915	COG1595	DNA-templated transcription, initiation
EQK04_00920	COG5662	AntiSigma factor
EQK04_00925	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EQK04_00930	COG4856	YbbR-like protein
EQK04_00935	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EQK04_00940	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EQK04_00960	COG1131	(ABC) transporter
EQK04_00970	COG1136	(ABC) transporter
EQK04_00980	COG1695	Transcriptional regulator
EQK04_00995	COG0535	radical SAM domain protein
EQK04_01000	COG1266	CAAX protease self-immunity
EQK04_01005	COG1131	(ABC) transporter
EQK04_01015	COG1413	lyase activity
EQK04_01020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQK04_01030	COG2311	Membrane
EQK04_01050	COG1476	TRANSCRIPTIONal
EQK04_01060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EQK04_01065	COG2207	Transcriptional regulator
EQK04_01080	COG1131	(ABC) transporter
EQK04_01095	COG1113	amino acid transport
EQK04_01100	COG0584	glycerophosphoryl diester phosphodiesterase
EQK04_01105	COG2271	Major facilitator Superfamily
EQK04_01115	COG1331	Highly conserved protein containing a thioredoxin domain
EQK04_01120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EQK04_01135	COG0640	Transcriptional regulator
EQK04_01150	COG1937	Protein conserved in bacteria
EQK04_01155	COG2210	Belongs to the sulfur carrier protein TusA family
EQK04_01165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EQK04_01165	COG0425	Belongs to the sulfur carrier protein TusA family
EQK04_01170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EQK04_01170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EQK04_01175	COG0425	Belongs to the sulfur carrier protein TusA family
EQK04_01180	COG0730	response to heat
EQK04_01190	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EQK04_01195	COG2814	Major facilitator Superfamily
EQK04_01210	COG1846	Transcriptional regulator
EQK04_01220	COG1683	Conserved Protein
EQK04_01235	COG0656	L-ascorbic acid biosynthetic process
EQK04_01240	COG0371	Dehydrogenase
EQK04_01250	COG0531	amino acid
EQK04_01260	COG3711	transcriptional antiterminator
EQK04_01265	COG1263	PTS System
EQK04_01265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQK04_01265	COG2190	(PTS) system
EQK04_01270	COG2723	6-phospho-beta-galactosidase activity
EQK04_01285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQK04_01285	COG3711	transcriptional antiterminator
EQK04_01290	COG1940	carbohydrate kinase activity
EQK04_01295	COG0383	alpha-mannosidase activity
EQK04_01300	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQK04_01305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQK04_01315	COG1404	Belongs to the peptidase S8 family
EQK04_01330	COG0833	amino acid
EQK04_01335	COG2040	homocysteine
EQK04_01340	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQK04_01365	COG2814	Major facilitator Superfamily
EQK04_01370	COG0456	acetyltransferase
EQK04_01385	COG1404	Belongs to the peptidase S8 family
EQK04_01395	COG1309	transcriptional regulator
EQK04_01400	COG1917	Cupin 2, conserved barrel domain protein
EQK04_01405	COG1846	Transcriptional regulator
EQK04_01410	COG0318	PFAM AMP-dependent synthetase and ligase
EQK04_01415	COG0531	amino acid
EQK04_01425	COG0596	Alpha beta hydrolase
EQK04_01430	COG1115	amino acid carrier protein
EQK04_01435	COG2066	Belongs to the glutaminase family
EQK04_01440	COG4191	Histidine kinase
EQK04_01445	COG0784	Response regulator, receiver
EQK04_01450	COG3012	SEC-C Motif Domain Protein
EQK04_01450	COG1405	negative regulation of cell septum assembly
EQK04_01460	COG0667	Aldo Keto reductase
EQK04_01465	COG3290	protein histidine kinase activity
EQK04_01470	COG3279	Response regulator of the LytR AlgR family
EQK04_01475	COG4555	ABC transporter
EQK04_01480	COG1668	transmembrane transport
EQK04_01500	COG3773	Cell wall hydrolase
EQK04_01505	COG1028	Short-chain dehydrogenase reductase Sdr
EQK04_01515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQK04_01520	COG2310	stress, protein
EQK04_01525	COG2310	stress, protein
EQK04_01530	COG2310	stress, protein
EQK04_01535	COG0861	Integral membrane protein TerC family
EQK04_01565	COG3853	Toxic anion resistance protein (TelA)
EQK04_01570	COG4175	Glycine betaine
EQK04_01570	COG0517	IMP dehydrogenase activity
EQK04_01575	COG4176	ABC-type proline glycine betaine transport system permease component
EQK04_01580	COG2113	Glycine betaine
EQK04_01595	COG1473	amidohydrolase
EQK04_01600	COG1288	antiporter activity
EQK04_01605	COG0039	L-malate dehydrogenase activity
EQK04_01610	COG1620	l-lactate permease
EQK04_01615	COG1609	Transcriptional regulator
EQK04_01620	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EQK04_01625	COG0561	phosphatase activity
EQK04_01630	COG0673	inositol 2-dehydrogenase activity
EQK04_01635	COG0738	Major facilitator superfamily
EQK04_01640	COG1280	lysine exporter protein (LysE YggA)
EQK04_01655	COG3403	YqcI/YcgG family
EQK04_01660	COG1113	amino acid transport
EQK04_01665	COG3665	Urea carboxylase-associated protein
EQK04_01670	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EQK04_01680	COG1012	belongs to the aldehyde dehydrogenase family
EQK04_01685	COG0710	3-dehydroquinate dehydratase activity
EQK04_01690	COG0028	Belongs to the TPP enzyme family
EQK04_01700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EQK04_01705	COG2271	Major facilitator Superfamily
EQK04_01720	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EQK04_01725	COG2226	methyltransferase
EQK04_01730	COG0583	DNA-binding transcription factor activity
EQK04_01735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EQK04_01740	COG3458	cephalosporin-C deacetylase activity
EQK04_01750	COG3541	Predicted nucleotidyltransferase
EQK04_01755	COG0506	proline dehydrogenase activity
EQK04_01760	COG1012	belongs to the aldehyde dehydrogenase family
EQK04_01765	COG2508	Transcriptional regulator
EQK04_01770	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EQK04_01775	COG0765	amino acid transport
EQK04_01780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQK04_01790	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EQK04_01795	COG1522	sequence-specific DNA binding
EQK04_01800	COG2746	aminoglycoside 3-N-acetyltransferase activity
EQK04_01810	COG3290	protein histidine kinase activity
EQK04_01810	COG0840	transmembrane signaling receptor activity
EQK04_01815	COG3209	COG3209 Rhs family protein
EQK04_01840	COG3842	ATPase activity
EQK04_01845	COG1176	ABC-type spermidine putrescine transport system, permease component I
EQK04_01855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EQK04_01860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EQK04_01865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EQK04_01880	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EQK04_01885	COG0697	spore germination
EQK04_01890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQK04_01900	COG3708	Transcriptional regulator
EQK04_01900	COG2207	Transcriptional regulator
EQK04_01910	COG2364	Membrane
EQK04_01915	COG1126	abc transporter atp-binding protein
EQK04_01920	COG0765	amino acid transport
EQK04_01925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQK04_01930	COG0412	Dienelactone hydrolase
EQK04_01935	COG0833	amino acid
EQK04_01940	COG3104	oligopeptide transport
EQK04_01945	COG5434	Belongs to the glycosyl hydrolase 28 family
EQK04_01950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQK04_01955	COG0456	acetyltransferase
EQK04_01960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQK04_01965	COG0765	amino acid transport
EQK04_01970	COG1126	abc transporter atp-binding protein
EQK04_01975	COG1473	amidohydrolase
EQK04_01980	COG2079	MmgE PrpD family protein
EQK04_01990	COG0745	RESPONSE REGULATOR receiver
EQK04_01995	COG3850	Histidine kinase
EQK04_01995	COG5002	protein histidine kinase activity
EQK04_02000	COG1366	Belongs to the anti-sigma-factor antagonist family
EQK04_02005	COG0527	aspartate kinase activity
EQK04_02010	COG2814	Major facilitator Superfamily
EQK04_02015	COG1309	transcriptional regulator
EQK04_02025	COG0640	Transcriptional regulator
EQK04_02035	COG0583	DNA-binding transcription factor activity
EQK04_02040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQK04_02045	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EQK04_02050	COG0531	amino acid
EQK04_02055	COG1012	belongs to the aldehyde dehydrogenase family
EQK04_02060	COG2249	NAD(P)H dehydrogenase (quinone) activity
EQK04_02065	COG4549	nuclear export factor GLE1
EQK04_02070	COG2372	response to copper ion
EQK04_02070	COG1276	copper resistance
EQK04_02075	COG2213	PTS system mannitol-specific
EQK04_02080	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQK04_02085	COG0246	Mannitol dehydrogenase
EQK04_02090	COG0840	transmembrane signaling receptor activity
EQK04_02125	COG0346	lactoylglutathione lyase activity
EQK04_02135	COG0561	phosphatase activity
EQK04_02140	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EQK04_02145	COG1914	H( )-stimulated, divalent metal cation uptake system
EQK04_02150	COG4336	lyase activity
EQK04_02155	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EQK04_02160	COG1984	allophanate hydrolase subunit 2
EQK04_02165	COG1414	Transcriptional regulator
EQK04_02170	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EQK04_02175	COG2755	lipolytic protein G-D-S-L family
EQK04_02185	COG3711	transcriptional antiterminator
EQK04_02190	COG2226	methyltransferase
EQK04_02195	COG1028	Short-chain dehydrogenase reductase Sdr
EQK04_02200	COG3871	stress protein (general stress protein 26)
EQK04_02220	COG2814	Major facilitator Superfamily
EQK04_02225	COG1802	Transcriptional regulator
EQK04_02230	COG1917	Cupin 2, conserved barrel domain protein
EQK04_02230	COG2207	Transcriptional regulator
EQK04_02235	COG0697	spore germination
EQK04_02240	COG0473	3-isopropylmalate dehydrogenase activity
EQK04_02245	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EQK04_02245	COG0551	DNA topoisomerase type I activity
EQK04_02250	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EQK04_02255	COG3706	GGDEF domain
EQK04_02260	COG5298	Protein conserved in bacteria
EQK04_02265	COG1215	transferase activity, transferring glycosyl groups
EQK04_02275	COG0531	amino acid
EQK04_02280	COG0028	Belongs to the TPP enzyme family
EQK04_02285	COG5444	nuclease activity
EQK04_02315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EQK04_02320	COG1914	H( )-stimulated, divalent metal cation uptake system
EQK04_02325	COG2261	transglycosylase associated protein
EQK04_02330	COG2217	Heavy metal translocating P-type atpase
EQK04_02335	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EQK04_02340	COG3290	protein histidine kinase activity
EQK04_02345	COG4565	transcriptional regulatory protein
EQK04_02350	COG1301	dicarboxylic acid transport
EQK04_02355	COG0628	permease
EQK04_02360	COG1301	dicarboxylic acid transport
EQK04_02365	COG1131	(ABC) transporter
EQK04_02370	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EQK04_02385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQK04_02390	COG1181	Belongs to the D-alanine--D-alanine ligase family
EQK04_02395	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EQK04_02410	COG0513	Belongs to the DEAD box helicase family
EQK04_02415	COG3402	PFAM membrane-flanked domain
EQK04_02420	COG3428	Bacterial PH domain
EQK04_02425	COG0705	Rhomboid family
EQK04_02430	COG0736	holo-[acyl-carrier-protein] synthase activity
EQK04_02435	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EQK04_02440	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EQK04_02445	COG0864	Transcriptional regulator
EQK04_02450	COG2337	Toxic component of a toxin-antitoxin (TA) module
EQK04_02455	COG1366	Belongs to the anti-sigma-factor antagonist family
EQK04_02460	COG1366	Belongs to the anti-sigma-factor antagonist family
EQK04_02465	COG2172	sigma factor antagonist activity
EQK04_02470	COG2208	phosphoserine phosphatase activity
EQK04_02475	COG1366	Belongs to the anti-sigma-factor antagonist family
EQK04_02480	COG2172	sigma factor antagonist activity
EQK04_02485	COG1191	sigma factor activity
EQK04_02490	COG2208	phosphoserine phosphatase activity
EQK04_02495	COG2183	response to ionizing radiation
EQK04_02505	COG3091	SprT-like family
EQK04_02510	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EQK04_02515	COG0022	dehydrogenase e1 component
EQK04_02520	COG0508	dehydrogenase complex catalyzes the overall conversion of
EQK04_02525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EQK04_02530	COG3284	Transcriptional regulator
EQK04_02575	COG1278	Cold shock
EQK04_02580	COG1263	PTS System
EQK04_02580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQK04_02580	COG2190	(PTS) system
EQK04_02585	COG3394	polysaccharide catabolic process
EQK04_02590	COG3711	transcriptional antiterminator
EQK04_02595	COG1064	alcohol dehydrogenase
EQK04_02600	COG0789	Transcriptional regulator
EQK04_02620	COG0477	Major facilitator Superfamily
EQK04_02635	COG4221	oxidoreductase activity
EQK04_02645	COG0252	asparaginase activity
EQK04_02650	COG2267	carboxylic ester hydrolase activity
EQK04_02665	COG2814	Major facilitator Superfamily
EQK04_02670	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EQK04_02675	COG2409	Drug exporters of the RND superfamily
EQK04_02680	COG4585	Histidine kinase
EQK04_02685	COG2197	response regulator
EQK04_02730	COG1309	transcriptional regulator
EQK04_02735	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EQK04_02740	COG1846	Transcriptional regulator
EQK04_02745	COG0778	Nitroreductase
EQK04_02760	COG1396	sequence-specific DNA binding
EQK04_02770	COG0456	acetyltransferase
EQK04_02785	COG4122	O-methyltransferase activity
EQK04_02795	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EQK04_02800	COG0697	spore germination
EQK04_02810	COG1301	dicarboxylic acid transport
EQK04_02850	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EQK04_02855	COG0802	atpase or kinase
EQK04_02860	COG1214	PFAM Peptidase M22, glycoprotease
EQK04_02865	COG0456	acetyltransferase
EQK04_02870	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EQK04_02875	COG0488	(ABC) transporter
EQK04_02880	COG0315	cyclic pyranopterin monophosphate synthase activity
EQK04_02885	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EQK04_02890	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EQK04_02895	COG0805	protein transport
EQK04_02910	COG1266	CAAX protease self-immunity
EQK04_02915	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EQK04_02920	COG0459	protein refolding
EQK04_02925	COG1846	Transcriptional regulator
EQK04_02930	COG0456	acetyltransferase
EQK04_02935	COG2808	Putative FMN-binding domain
EQK04_02940	COG1876	peptidase activity
EQK04_02965	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EQK04_02970	COG0823	Involved in the tonB-independent uptake of proteins
EQK04_02980	COG2132	Multicopper oxidase
EQK04_02985	COG1113	amino acid transport
EQK04_02990	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EQK04_02995	COG0714	Associated with various cellular activities
EQK04_03000	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EQK04_03005	COG1305	Transglutaminase-like
EQK04_03010	COG0519	Catalyzes the synthesis of GMP from XMP
EQK04_03010	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EQK04_03035	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EQK04_03045	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EQK04_03080	COG3279	Response regulator of the LytR AlgR family
EQK04_03100	COG1595	DNA-templated transcription, initiation
EQK04_03110	COG2814	Major facilitator Superfamily
EQK04_03115	COG0583	DNA-binding transcription factor activity
EQK04_03120	COG2252	PERMEase
EQK04_03125	COG5583	Uncharacterized small protein (DUF2292)
EQK04_03130	COG3064	Membrane
EQK04_03135	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EQK04_03145	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EQK04_03150	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EQK04_03155	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EQK04_03160	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EQK04_03165	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EQK04_03170	COG0047	phosphoribosylformylglycinamidine synthase activity
EQK04_03175	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EQK04_03180	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EQK04_03185	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EQK04_03190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EQK04_03195	COG0138	bifunctional purine biosynthesis protein purh
EQK04_03200	COG0151	Belongs to the GarS family
EQK04_03220	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EQK04_03225	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EQK04_03230	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EQK04_03235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EQK04_03245	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EQK04_03250	COG4496	protein, YerC YecD
EQK04_03260	COG0069	glutamate synthase activity
EQK04_03275	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EQK04_03280	COG0210	DNA helicase
EQK04_03285	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EQK04_03290	COG4851	CamS sex pheromone cAM373 precursor
EQK04_03295	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EQK04_03300	COG1285	pathogenesis
EQK04_03305	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EQK04_03310	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EQK04_03315	COG0154	amidase activity
EQK04_03320	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EQK04_03325	COG1309	transcriptional regulator
EQK04_03330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EQK04_03335	COG1957	nucleoside hydrolase
EQK04_03340	COG1597	lipid kinase activity
EQK04_03345	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EQK04_03370	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EQK04_03385	COG1959	2 iron, 2 sulfur cluster binding
EQK04_03390	COG0492	ferredoxin-NADP+ reductase activity
EQK04_03405	COG1486	melibiose metabolic process
EQK04_03415	COG2211	Major facilitator Superfamily
EQK04_03445	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EQK04_03450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EQK04_03455	COG1442	glycosyl transferase family 8
EQK04_03460	COG1216	Glycosyl transferase, family 2
EQK04_03465	COG1442	glycosyl transferase family 8
EQK04_03470	COG2223	nitrite transmembrane transporter activity
EQK04_03480	COG0471	metal ion transport
EQK04_03495	COG0071	Belongs to the small heat shock protein (HSP20) family
EQK04_03510	COG0531	amino acid
EQK04_03515	COG0463	Glycosyl transferase, family 2
EQK04_03515	COG0457	Tetratricopeptide repeat
EQK04_03520	COG0488	(ABC) transporter
EQK04_03525	COG1469	GTP cyclohydrolase I activity
EQK04_03530	COG0789	Transcriptional regulator
EQK04_03535	COG2814	Major facilitator Superfamily
EQK04_03540	COG0488	(ABC) transporter
EQK04_03545	COG0513	Belongs to the DEAD box helicase family
EQK04_03550	COG2130	NADP-dependent
EQK04_03570	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EQK04_03570	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EQK04_03575	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EQK04_03585	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EQK04_03585	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EQK04_03595	COG3290	protein histidine kinase activity
EQK04_03600	COG4565	transcriptional regulatory protein
EQK04_03605	COG3181	Tripartite tricarboxylate transporter family receptor
EQK04_03610	COG2851	Citrate transporter
EQK04_03620	COG3479	Phenolic acid decarboxylase
EQK04_03625	COG1695	Transcriptional regulator
EQK04_03630	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EQK04_03640	COG1254	Belongs to the acylphosphatase family
EQK04_03645	COG2258	MOSC domain
EQK04_03660	COG0024	Methionine aminopeptidase
EQK04_03665	COG1263	PTS System
EQK04_03665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQK04_03670	COG3739	integral membrane protein
EQK04_03685	COG1368	sulfuric ester hydrolase activity
EQK04_03690	COG0076	glutamate decarboxylase activity
EQK04_03705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQK04_03705	COG1263	PTS System
EQK04_03710	COG0366	Alpha amylase catalytic
EQK04_03715	COG2188	Transcriptional regulator
EQK04_03725	COG0737	Belongs to the 5'-nucleotidase family
EQK04_03730	COG0693	protein deglycase activity
EQK04_03735	COG4840	Belongs to the UPF0435 family
EQK04_03740	COG1115	amino acid carrier protein
EQK04_03750	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EQK04_03755	COG4980	gas vesicle protein
EQK04_03760	COG1295	ribonuclease BN
EQK04_03765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EQK04_03770	COG0477	Major facilitator Superfamily
EQK04_03780	COG0387	Pfam Sodium calcium exchanger
EQK04_03795	COG0217	transcriptional regulatory protein
EQK04_03805	COG0668	transmembrane transport
EQK04_03810	COG0535	radical SAM domain protein
EQK04_03820	COG0726	polysaccharide deacetylase
EQK04_03830	COG0598	Magnesium transport protein CorA
EQK04_03840	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EQK04_03845	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EQK04_03865	COG0789	Transcriptional regulator
EQK04_03870	COG2814	Major facilitator Superfamily
EQK04_03925	COG2076	Multidrug Resistance protein
EQK04_03930	COG2076	Multidrug Resistance protein
EQK04_03935	COG1309	transcriptional regulator
EQK04_03945	COG4637	Psort location Cytoplasmic, score
EQK04_03950	COG2755	lipolytic protein G-D-S-L family
EQK04_03955	COG0492	ferredoxin-NADP+ reductase activity
EQK04_03960	COG2169	Transcriptional regulator
EQK04_03965	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EQK04_03970	COG1132	(ABC) transporter
EQK04_03975	COG1742	UPF0060 membrane protein
EQK04_03980	COG1595	DNA-templated transcription, initiation
EQK04_04000	COG2318	DinB family
EQK04_04010	COG1846	Transcriptional regulator
EQK04_04015	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EQK04_04015	COG0392	lysyltransferase activity
EQK04_04035	COG0778	Nitroreductase
EQK04_04050	COG1090	epimerase
EQK04_04055	COG2137	regulation of response to DNA damage stimulus
EQK04_04080	COG0463	Glycosyl transferase, family 2
EQK04_04085	COG4485	Bacterial membrane protein, YfhO
EQK04_04090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EQK04_04105	COG2140	Oxalate decarboxylase
EQK04_04115	COG1191	sigma factor activity
EQK04_04125	COG1988	membrane-bound metal-dependent
EQK04_04130	COG1194	a g-specific adenine glycosylase
EQK04_04140	COG1028	Short-chain dehydrogenase reductase Sdr
EQK04_04155	COG3557	Belongs to the UPF0374 family
EQK04_04160	COG1132	(ABC) transporter
EQK04_04165	COG0444	Belongs to the ABC transporter superfamily
EQK04_04170	COG4608	Belongs to the ABC transporter superfamily
EQK04_04175	COG0747	negative chemotaxis
EQK04_04190	COG4129	membrane
EQK04_04195	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EQK04_04200	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EQK04_04205	COG0735	belongs to the Fur family
EQK04_04350	COG1368	sulfuric ester hydrolase activity
EQK04_04355	COG0681	Belongs to the peptidase S26 family
EQK04_04360	COG2873	o-acetylhomoserine
EQK04_04370	COG1116	anion transmembrane transporter activity
EQK04_04375	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EQK04_04380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EQK04_04395	COG1131	(ABC) transporter
EQK04_04425	COG3382	B3 4 domain protein
EQK04_04430	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EQK04_04440	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EQK04_04445	COG2766	serine protein kinase
EQK04_04450	COG2718	Belongs to the UPF0229 family
EQK04_04455	COG1566	PFAM secretion protein HlyD family protein
EQK04_04460	COG2814	Major facilitator Superfamily
EQK04_04465	COG0655	NAD(P)H dehydrogenase (quinone) activity
EQK04_04475	COG1278	Cold shock
EQK04_04485	COG3706	GGDEF domain
EQK04_04510	COG5577	PFAM Coat F domain
EQK04_04515	COG5002	protein histidine kinase activity
EQK04_04520	COG0737	Belongs to the 5'-nucleotidase family
EQK04_04520	COG4085	toxin activity
EQK04_04520	COG1525	nuclease
EQK04_04525	COG3764	Sortase (surface protein transpeptidase)
EQK04_04530	COG0564	pseudouridine synthase activity
EQK04_04540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EQK04_04545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EQK04_04545	COG3153	acetyltransferase
EQK04_04565	COG3835	regulator
EQK04_04570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EQK04_04575	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EQK04_04580	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EQK04_04585	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EQK04_04590	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EQK04_04595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EQK04_04600	COG2203	Gaf domain
EQK04_04600	COG4585	Histidine kinase
EQK04_04605	COG2197	response regulator
EQK04_04620	COG0753	catalase activity
EQK04_04625	COG1959	2 iron, 2 sulfur cluster binding
EQK04_04630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EQK04_04630	COG1017	nitric oxide dioxygenase activity
EQK04_04635	COG2719	SpoVR family
EQK04_04640	COG1785	Belongs to the alkaline phosphatase family
EQK04_04645	COG0791	NLP P60 protein
EQK04_04645	COG1388	LysM domain
EQK04_04650	COG0531	amino acid
EQK04_04665	COG1595	DNA-templated transcription, initiation
EQK04_04670	COG0204	Acyl-transferase
EQK04_04675	COG1253	flavin adenine dinucleotide binding
EQK04_04680	COG0789	Transcriptional regulator
EQK04_04685	COG1253	flavin adenine dinucleotide binding
EQK04_04700	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EQK04_04705	COG0584	glycerophosphoryl diester phosphodiesterase
EQK04_04715	COG0668	transmembrane transport
EQK04_04720	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EQK04_04725	COG0726	polysaccharide deacetylase
EQK04_04730	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EQK04_04740	COG0589	response to stress
EQK04_04745	COG1132	(ABC) transporter
EQK04_04750	COG1132	(ABC) transporter
EQK04_04755	COG0702	epimerase
EQK04_04765	COG3842	ATPase activity
EQK04_04770	COG2508	Transcriptional regulator
EQK04_04780	COG0189	ligase activity
EQK04_04785	COG0189	ligase activity
EQK04_04790	COG4399	Belongs to the UPF0754 family
EQK04_04795	COG3679	Belongs to the UPF0342 family
EQK04_04800	COG0561	phosphatase activity
EQK04_04805	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EQK04_04815	COG0475	glutathione-regulated potassium exporter activity
EQK04_04820	COG0490	domain, Protein
EQK04_04830	COG1024	Enoyl-CoA hydratase
EQK04_04840	COG0420	3'-5' exonuclease activity
EQK04_04845	COG4717	serine-type aminopeptidase activity
EQK04_04850	COG3481	metal-dependent phosphohydrolase, HD sub domain
EQK04_04860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EQK04_04890	COG1846	Transcriptional regulator
EQK04_04895	COG4980	gas vesicle protein
EQK04_04910	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EQK04_04915	COG0537	adenosine 5'-monophosphoramidase activity
EQK04_04920	COG1131	(ABC) transporter
EQK04_04925	COG4473	ABC transporter
EQK04_04935	COG1473	amidohydrolase
EQK04_04950	COG2329	Antibiotic biosynthesis monooxygenase
EQK04_04955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EQK04_04960	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EQK04_04975	COG1309	transcriptional regulator
EQK04_04980	COG1511	domain protein
EQK04_04985	COG1363	Peptidase, m42
EQK04_04990	COG1301	dicarboxylic acid transport
EQK04_05000	COG1234	tRNA 3'-trailer cleavage
EQK04_05005	COG0095	Lipoate-protein ligase
EQK04_05010	COG0318	PFAM AMP-dependent synthetase and ligase
EQK04_05020	COG0501	Belongs to the peptidase M48B family
EQK04_05025	COG1404	Belongs to the peptidase S8 family
EQK04_05030	COG0406	alpha-ribazole phosphatase activity
EQK04_05035	COG0840	transmembrane signaling receptor activity
EQK04_05040	COG0723	plastoquinol--plastocyanin reductase activity
EQK04_05040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EQK04_05045	COG1028	Short-chain dehydrogenase reductase Sdr
EQK04_05055	COG4903	ComK protein
EQK04_05070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQK04_05075	COG2814	Major facilitator Superfamily
EQK04_05080	COG2732	(Barnase) inhibitor
EQK04_05085	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQK04_05090	COG4605	iron ion homeostasis
EQK04_05095	COG4604	ABC transporter, ATP-binding protein
EQK04_05100	COG4607	ABC-type enterochelin transport system periplasmic component
EQK04_05105	COG1316	TRANSCRIPTIONal
EQK04_05125	COG0398	Pfam SNARE associated Golgi protein
EQK04_05130	COG0681	Belongs to the peptidase S26 family
EQK04_05140	COG3180	Ammonia monooxygenase
EQK04_05155	COG2259	Doxx family
EQK04_05160	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EQK04_05165	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EQK04_05170	COG1074	ATP-dependent DNA helicase activity
EQK04_05175	COG0420	3'-5' exonuclease activity
EQK04_05180	COG0419	ATPase involved in DNA repair
EQK04_05185	COG1403	HNH endonuclease
EQK04_05225	COG5337	Spore coat protein CotH
EQK04_05240	COG0179	Fumarylacetoacetate (FAA) hydrolase
EQK04_05255	COG0367	asparagine synthase
EQK04_05270	COG1562	ergosterol biosynthetic process
EQK04_05275	COG0534	Mate efflux family protein
EQK04_05280	COG2207	Transcriptional regulator
EQK04_05280	COG1917	Cupin 2, conserved barrel domain protein
EQK04_05305	COG0076	glutamate decarboxylase activity
EQK04_05340	COG0646	methionine synthase
EQK04_05340	COG1410	methionine synthase
EQK04_05345	COG0646	methionine synthase
EQK04_05345	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EQK04_05350	COG1666	GTP binding
EQK04_05355	COG2996	Protein conserved in bacteria
EQK04_05365	COG0840	transmembrane signaling receptor activity
EQK04_05370	COG1307	EDD domain protein, DegV family
EQK04_05375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQK04_05395	COG0561	phosphatase activity
EQK04_05400	COG1073	alpha beta
EQK04_05405	COG2151	metal-sulfur cluster biosynthetic enzyme
EQK04_05410	COG0277	FAD linked oxidase domain protein
EQK04_05415	COG2271	Major facilitator Superfamily
EQK04_05420	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EQK04_05425	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EQK04_05430	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EQK04_05435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EQK04_05440	COG0505	Belongs to the CarA family
EQK04_05445	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EQK04_05450	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EQK04_05460	COG2814	Major facilitator Superfamily
EQK04_05470	COG2267	carboxylic ester hydrolase activity
EQK04_05480	COG1744	ABC transporter substrate-binding protein PnrA-like
EQK04_05495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EQK04_05500	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EQK04_05505	COG5504	Zn-dependent protease
EQK04_05510	COG0444	Belongs to the ABC transporter superfamily
EQK04_05515	COG4608	Belongs to the ABC transporter superfamily
EQK04_05525	COG0601	transmembrane transport
EQK04_05530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EQK04_05540	COG0180	Tryptophanyl-tRNA synthetase
EQK04_05545	COG4166	transmembrane transport
EQK04_05550	COG0601	transmembrane transport
EQK04_05555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EQK04_05560	COG0444	Belongs to the ABC transporter superfamily
EQK04_05565	COG4608	Belongs to the ABC transporter superfamily
EQK04_05575	COG0456	acetyltransferase
EQK04_05580	COG1393	Belongs to the ArsC family
EQK04_05585	COG0861	Integral membrane protein TerC family
EQK04_05590	COG4862	establishment of competence for transformation
EQK04_05595	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EQK04_05605	COG1164	Oligoendopeptidase f
EQK04_05620	COG2346	COG2346, Truncated hemoglobins
EQK04_05625	COG0741	lytic transglycosylase activity
EQK04_05630	COG4116	CYTH
EQK04_05640	COG2357	RelA SpoT domain protein
EQK04_05645	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EQK04_05650	COG0564	pseudouridine synthase activity
EQK04_05655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EQK04_05660	COG0475	glutathione-regulated potassium exporter activity
EQK04_05660	COG0569	domain protein
EQK04_05665	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EQK04_05670	COG0352	thiamine-phosphate diphosphorylase activity
EQK04_05680	COG2104	thiamine diphosphate biosynthetic process
EQK04_05685	COG2022	thiamine diphosphate biosynthetic process
EQK04_05690	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EQK04_05695	COG0351	phosphomethylpyrimidine kinase
EQK04_05700	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EQK04_05755	COG0210	DNA helicase
EQK04_05765	COG2153	protein acetylation
EQK04_05770	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EQK04_05775	COG2382	esterase
EQK04_05780	COG0626	cystathionine gamma-synthase activity
EQK04_05785	COG0626	cystathionine gamma-synthase activity
EQK04_05795	COG3620	sequence-specific DNA binding
EQK04_05810	COG0825	malonyl-CoA metabolic process
EQK04_05825	COG0457	Tetratricopeptide repeat
EQK04_05835	COG1280	lysine exporter protein (LysE YggA)
EQK04_05845	COG2364	Membrane
EQK04_05880	COG3173	Aminoglycoside phosphotransferase
EQK04_05885	COG0583	DNA-binding transcription factor activity
EQK04_05905	COG0583	DNA-binding transcription factor activity
EQK04_05910	COG2807	transmembrane transport
EQK04_05940	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EQK04_05950	COG1309	transcriptional regulator
EQK04_05960	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EQK04_05965	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EQK04_05970	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EQK04_05975	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EQK04_05995	COG4195	phage-related replication protein
EQK04_06000	COG2856	Zn peptidase
EQK04_06005	COG3409	Peptidoglycan-binding domain 1 protein
EQK04_06005	COG5632	N-Acetylmuramoyl-L-alanine amidase
EQK04_06025	COG0306	phosphate transporter
EQK04_06030	COG1392	Phosphate transport regulator
EQK04_06040	COG0405	Gamma-glutamyltransferase
EQK04_06045	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EQK04_06055	COG4208	sulfate ABC transporter
EQK04_06060	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EQK04_06070	COG3775	system Galactitol-specific IIC component
EQK04_06085	COG1063	alcohol dehydrogenase
EQK04_06090	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EQK04_06095	COG0508	dehydrogenase complex catalyzes the overall conversion of
EQK04_06095	COG0022	dehydrogenase e1 component
EQK04_06100	COG0508	dehydrogenase complex catalyzes the overall conversion of
EQK04_06105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EQK04_06110	COG1028	Short-chain dehydrogenase reductase Sdr
EQK04_06115	COG1028	Short-chain dehydrogenase reductase Sdr
EQK04_06120	COG2390	Transcriptional regulator
EQK04_06130	COG0531	amino acid
EQK04_06135	COG0346	lactoylglutathione lyase activity
EQK04_06145	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EQK04_06150	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EQK04_06155	COG2362	D-Aminopeptidase
EQK04_06160	COG0601	transmembrane transport
EQK04_06165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EQK04_06170	COG0444	Belongs to the ABC transporter superfamily
EQK04_06175	COG4166	transmembrane transport
EQK04_06180	COG1619	proteins homologs of microcin C7 resistance protein MccF
EQK04_06185	COG4948	Mandelate Racemase Muconate Lactonizing
EQK04_06190	COG0791	NLP P60 protein
EQK04_06195	COG4608	Belongs to the ABC transporter superfamily
EQK04_06200	COG1834	amidinotransferase
EQK04_06205	COG1607	acyl-coa hydrolase
EQK04_06210	COG1695	Transcriptional regulator
EQK04_06225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EQK04_06235	COG2076	Multidrug Resistance protein
EQK04_06240	COG2076	Multidrug Resistance protein
EQK04_06250	COG0788	formyltetrahydrofolate deformylase activity
EQK04_06255	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EQK04_06260	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EQK04_06265	COG0457	Tetratricopeptide repeat
EQK04_06275	COG1764	response to oxidative stress
EQK04_06280	COG1846	Transcriptional regulator
EQK04_06285	COG1764	response to oxidative stress
EQK04_06290	COG0590	tRNA wobble adenosine to inosine editing
EQK04_06295	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EQK04_06300	COG1404	Belongs to the peptidase S8 family
EQK04_06315	COG0745	RESPONSE REGULATOR receiver
EQK04_06320	COG5002	protein histidine kinase activity
EQK04_06320	COG3850	Histidine kinase
EQK04_06325	COG3212	peptidase
EQK04_06330	COG3212	peptidase
EQK04_06340	COG2239	Acts as a magnesium transporter
EQK04_06350	COG0583	DNA-binding transcription factor activity
EQK04_06360	COG0789	Transcriptional regulator
EQK04_06370	COG1846	Transcriptional regulator
EQK04_06375	COG5001	Diguanylate cyclase
EQK04_06375	COG3300	MHYT domain
EQK04_06380	COG0586	Pfam SNARE associated Golgi protein
EQK04_06385	COG0861	Integral membrane protein TerC family
EQK04_06390	COG1191	sigma factor activity
EQK04_06410	COG0501	Belongs to the peptidase M48B family
EQK04_06415	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EQK04_06420	COG2323	membrane
EQK04_06430	COG3594	Acyltransferase
EQK04_06435	COG5002	protein histidine kinase activity
EQK04_06440	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EQK04_06445	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EQK04_06450	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EQK04_06455	COG0436	Aminotransferase
EQK04_06460	COG1850	ribulose-bisphosphate carboxylase activity
EQK04_06465	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EQK04_06470	COG0235	Class ii aldolase
EQK04_06475	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EQK04_06485	COG3852	Histidine kinase
EQK04_06490	COG1846	Transcriptional regulator
EQK04_06495	COG1360	Flagellar Motor Protein
EQK04_06500	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EQK04_06505	COG0542	response to heat
EQK04_06510	COG3949	Membrane
EQK04_06515	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EQK04_06520	COG0720	synthase
EQK04_06525	COG0602	queuosine metabolic process
EQK04_06530	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EQK04_06545	COG4873	Protein conserved in bacteria
EQK04_06555	COG3773	Cell wall hydrolase
EQK04_06560	COG2244	polysaccharide biosynthetic process
EQK04_06565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQK04_06570	COG2217	Heavy metal translocating P-type atpase
EQK04_06575	COG0006	proline dipeptidase activity
EQK04_06580	COG1609	Transcriptional regulator
EQK04_06585	COG3711	transcriptional antiterminator
EQK04_06590	COG1263	PTS System
EQK04_06590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQK04_06590	COG2190	(PTS) system
EQK04_06595	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQK04_06600	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EQK04_06610	COG1533	DNA photolyase activity
EQK04_06615	COG0840	transmembrane signaling receptor activity
EQK04_06625	COG2084	Dehydrogenase
EQK04_06630	COG2340	Cysteine-rich secretory protein family
EQK04_06635	COG0768	penicillin binding
EQK04_06640	COG4191	Histidine kinase
EQK04_06645	COG0436	Aminotransferase
EQK04_06650	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EQK04_06655	COG1714	RDD family
EQK04_06665	COG0784	Response regulator, receiver
EQK04_06665	COG0835	chemotaxis
EQK04_06675	COG1917	Cupin 2, conserved barrel domain protein
EQK04_06675	COG2207	Transcriptional regulator
EQK04_06680	COG0697	spore germination
EQK04_06695	COG2814	Major facilitator Superfamily
EQK04_06700	COG1376	ErfK ybiS ycfS ynhG family protein
EQK04_06705	COG1408	metallophosphoesterase
EQK04_06710	COG1028	Short-chain dehydrogenase reductase Sdr
EQK04_06715	COG2200	EAL domain
EQK04_06720	COG3546	catalase activity
EQK04_06725	COG4703	Protein of unknown function (DUF1797)
EQK04_06730	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EQK04_06740	COG0517	IMP dehydrogenase activity
EQK04_06745	COG0583	DNA-binding transcription factor activity
EQK04_06755	COG0716	FMN binding
EQK04_06765	COG0716	FMN binding
EQK04_06770	COG2171	N-acyltransferase activity
EQK04_06775	COG1473	amidohydrolase
EQK04_06785	COG0668	transmembrane transport
EQK04_06790	COG0450	alkyl hydroperoxide reductase
EQK04_06795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQK04_06810	COG0746	molybdenum cofactor guanylyltransferase activity
EQK04_06815	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EQK04_06820	COG0303	'Molybdopterin
EQK04_06825	COG1763	Mo-molybdopterin cofactor biosynthetic process
EQK04_06830	COG0314	molybdopterin synthase activity
EQK04_06835	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EQK04_06850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EQK04_06855	COG1136	(ABC) transporter
EQK04_06860	COG0577	efflux transmembrane transporter activity
EQK04_06865	COG1349	DNA-binding transcription factor activity
EQK04_06870	COG1105	Belongs to the carbohydrate kinase PfkB family
EQK04_06875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQK04_06875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQK04_06875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQK04_06880	COG0681	Belongs to the peptidase S26 family
EQK04_06890	COG0488	(ABC) transporter
EQK04_06905	COG2309	aminopeptidase activity
EQK04_06910	COG1077	Cell shape determining protein MreB Mrl
EQK04_06915	COG2002	toxin-antitoxin pair type II binding
EQK04_06920	COG3852	Histidine kinase
EQK04_06925	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EQK04_06925	COG2105	PFAM AIG2 family protein
EQK04_06930	COG0569	domain protein
EQK04_06935	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EQK04_06940	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EQK04_06950	COG0561	phosphatase activity
EQK04_06955	COG0242	peptide deformylase activity
EQK04_06970	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EQK04_06975	COG0022	dehydrogenase e1 component
EQK04_06980	COG0508	dehydrogenase complex catalyzes the overall conversion of
EQK04_06985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EQK04_06990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQK04_07000	COG1982	Orn Lys Arg decarboxylase major
EQK04_07005	COG4476	Belongs to the UPF0223 family
EQK04_07010	COG4493	Belongs to the UPF0637 family
EQK04_07020	COG0483	inositol monophosphate 1-phosphatase activity
EQK04_07035	COG1595	DNA-templated transcription, initiation
EQK04_07065	COG4896	Protein conserved in bacteria
EQK04_07075	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EQK04_07080	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EQK04_07085	COG2066	Belongs to the glutaminase family
EQK04_07090	COG4838	Belongs to the UPF0358 family
EQK04_07095	COG0772	Belongs to the SEDS family
EQK04_07100	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EQK04_07110	COG1612	heme a metabolic process
EQK04_07115	COG0109	protoheme IX farnesyltransferase activity
EQK04_07120	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EQK04_07120	COG2010	Cytochrome c
EQK04_07125	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EQK04_07130	COG1845	cytochrome c oxidase, subunit III
EQK04_07135	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EQK04_07140	COG3336	cytochrome c oxidase
EQK04_07150	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EQK04_07155	COG2340	Cysteine-rich secretory protein family
EQK04_07175	COG3679	Belongs to the UPF0342 family
EQK04_07180	COG4471	UPF0298 protein
EQK04_07185	COG0742	ribosomal rna small subunit methyltransferase
EQK04_07190	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EQK04_07195	COG3314	Sporulation integral membrane protein YlbJ
EQK04_07200	COG1752	Esterase of the alpha-beta hydrolase superfamily
EQK04_07205	COG3480	Lon protease (S16) C-terminal proteolytic domain
EQK04_07215	COG1399	metal-binding, possibly nucleic acid-binding protein
EQK04_07220	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EQK04_07230	COG0454	-acetyltransferase
EQK04_07235	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EQK04_07240	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EQK04_07245	COG2001	Belongs to the MraZ family
EQK04_07250	COG0275	rRNA processing
EQK04_07255	COG4839	cell division protein FtsL
EQK04_07270	COG0768	penicillin binding
EQK04_07275	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EQK04_07280	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EQK04_07285	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EQK04_07290	COG0772	Belongs to the SEDS family
EQK04_07295	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EQK04_07300	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EQK04_07305	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EQK04_07310	COG3879	Bacterial protein of unknown function (DUF881)
EQK04_07315	COG3879	Bacterial protein of unknown function (DUF881)
EQK04_07320	COG3856	small basic protein
EQK04_07325	COG0849	cell division
EQK04_07330	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EQK04_07335	COG4412	M6 family metalloprotease domain protein
EQK04_07335	COG1404	Belongs to the peptidase S8 family
EQK04_07345	COG1191	sigma factor activity
EQK04_07350	COG1191	sigma factor activity
EQK04_07355	COG2390	Transcriptional regulator
EQK04_07370	COG3730	PTS system glucitol sorbitol-specific
EQK04_07375	COG3732	PTS system glucitol sorbitol-specific
EQK04_07385	COG1119	ATPase activity
EQK04_07390	COG1873	PFAM PRC-barrel domain
EQK04_07400	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EQK04_07405	COG1799	cell septum assembly
EQK04_07410	COG0762	integral membrane protein
EQK04_07415	COG2302	S4 RNA-binding domain
EQK04_07420	COG3599	regulation of cell shape
EQK04_07425	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EQK04_07430	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EQK04_07435	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EQK04_07440	COG0564	pseudouridine synthase activity
EQK04_07445	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EQK04_07450	COG2233	PERMEase
EQK04_07455	COG0540	Belongs to the ATCase OTCase family
EQK04_07460	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EQK04_07465	COG0505	Belongs to the CarA family
EQK04_07470	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EQK04_07475	COG0543	2 iron, 2 sulfur cluster binding
EQK04_07480	COG0167	dihydroorotate dehydrogenase activity
EQK04_07485	COG0284	orotidine-5'-phosphate decarboxylase activity
EQK04_07490	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EQK04_07500	COG0175	sulfate reduction
EQK04_07505	COG0306	phosphate transporter
EQK04_07510	COG2046	Belongs to the sulfate adenylyltransferase family
EQK04_07515	COG0529	Catalyzes the synthesis of activated sulfate
EQK04_07520	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EQK04_07525	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
EQK04_07530	COG1648	precorrin-2 dehydrogenase activity
EQK04_07540	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EQK04_07545	COG1561	YicC-like family, N-terminal region
EQK04_07550	COG2052	Domain of unknown function (DUF370)
EQK04_07555	COG0194	GDP metabolic process
EQK04_07560	COG1758	RNA polymerase activity
EQK04_07565	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EQK04_07570	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EQK04_07575	COG0242	peptide deformylase activity
EQK04_07580	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EQK04_07585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EQK04_07585	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EQK04_07590	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EQK04_07595	COG0631	protein serine/threonine phosphatase activity
EQK04_07600	COG2815	serine threonine protein kinase
EQK04_07600	COG0515	serine threonine protein kinase
EQK04_07605	COG1162	GTPase activity
EQK04_07610	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EQK04_07615	COG1564	THIamine pyrophosphokinase
EQK04_07625	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EQK04_07630	COG1302	Protein conserved in bacteria
EQK04_07635	COG1461	Dihydroxyacetone kinase
EQK04_07640	COG1760	l-serine dehydratase
EQK04_07645	COG1760	l-serine dehydratase
EQK04_07650	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EQK04_07655	COG1349	DNA-binding transcription factor activity
EQK04_07660	COG0416	fatty acid biosynthetic process
EQK04_07665	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EQK04_07670	COG1028	Short-chain dehydrogenase reductase Sdr
EQK04_07675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EQK04_07685	COG1196	nuclear chromosome segregation
EQK04_07690	COG0552	protein localization to endoplasmic reticulum
EQK04_07695	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EQK04_07700	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EQK04_07705	COG0228	four-way junction DNA binding
EQK04_07710	COG1837	Belongs to the UPF0109 family
EQK04_07720	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EQK04_07725	COG0336	Belongs to the RNA methyltransferase TrmD family
EQK04_07730	COG0335	large ribosomal subunit rRNA binding
EQK04_07735	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EQK04_07740	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EQK04_07750	COG2257	FlhB HrpN YscU SpaS Family
EQK04_07755	COG0045	succinate-CoA ligase (ADP-forming) activity
EQK04_07760	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EQK04_07765	COG0758	DNA mediated transformation
EQK04_07770	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EQK04_07775	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EQK04_07780	COG4974	Belongs to the 'phage' integrase family
EQK04_07785	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EQK04_07790	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EQK04_07795	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EQK04_07800	COG1815	bacterial-type flagellum-dependent cell motility
EQK04_07805	COG1558	bacterial-type flagellum-dependent cell motility
EQK04_07810	COG1677	Flagellar hook-basal body complex protein FliE
EQK04_07815	COG1766	The M ring may be actively involved in energy transduction
EQK04_07820	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EQK04_07825	COG1317	bacterial-type flagellum organization
EQK04_07830	COG1157	protein secretion by the type III secretion system
EQK04_07835	COG2882	bacterial-type flagellum organization
EQK04_07840	COG3334	PFAM MgtE intracellular
EQK04_07845	COG3144	bacterial-type flagellum assembly
EQK04_07850	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EQK04_07855	COG4786	Flagellar basal body rod
EQK04_07860	COG1582	Flagellar protein (FlbD)
EQK04_07865	COG1580	Controls the rotational direction of flagella during chemotaxis
EQK04_07870	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EQK04_07875	COG1776	CheC inhibitor of MCP methylation
EQK04_07875	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EQK04_07880	COG2201	protein-glutamate methylesterase activity
EQK04_07885	COG3190	flagellar
EQK04_07890	COG1338	Plays a role in the flagellum-specific transport system
EQK04_07895	COG1987	bacterial-type flagellum assembly
EQK04_07900	COG1684	flagellar biosynthetic protein fliR
EQK04_07905	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EQK04_07910	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EQK04_07915	COG1419	protein localization to endoplasmic reticulum
EQK04_07920	COG0455	bacterial-type flagellum organization
EQK04_07925	COG2201	protein-glutamate methylesterase activity
EQK04_07930	COG0643	Histidine kinase
EQK04_07930	COG2198	Histidine kinase
EQK04_07935	COG0835	chemotaxis
EQK04_07940	COG1776	CheC inhibitor of MCP methylation
EQK04_07950	COG1191	sigma factor activity
EQK04_07965	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EQK04_07970	COG0528	UMP kinase activity
EQK04_07975	COG0233	cytoplasmic translational termination
EQK04_07980	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EQK04_07985	COG4589	Belongs to the CDS family
EQK04_07990	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EQK04_07995	COG0750	zinc metalloprotease
EQK04_08000	COG0442	prolyl-tRNA aminoacylation
EQK04_08005	COG2176	DNA-directed DNA polymerase activity
EQK04_08020	COG3693	PFAM glycoside hydrolase, family 10
EQK04_08035	COG0779	Required for maturation of 30S ribosomal subunits
EQK04_08040	COG0195	Participates in both transcription termination and antitermination
EQK04_08045	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EQK04_08050	COG1358	cellular component organization or biogenesis
EQK04_08055	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EQK04_08060	COG1550	Protein conserved in bacteria
EQK04_08065	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EQK04_08070	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EQK04_08075	COG0196	riboflavin kinase activity
EQK04_08080	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EQK04_08085	COG1185	polyribonucleotide nucleotidyltransferase activity
EQK04_08090	COG0726	polysaccharide deacetylase
EQK04_08095	COG0612	Peptidase, M16
EQK04_08105	COG1873	PFAM PRC-barrel domain
EQK04_08110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EQK04_08115	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EQK04_08120	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EQK04_08125	COG0527	aspartate kinase activity
EQK04_08135	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EQK04_08140	COG0740	serine-type endopeptidase activity
EQK04_08150	COG4980	gas vesicle protein
EQK04_08150	COG1674	ftsk spoiiie
EQK04_08155	COG2188	Transcriptional regulator
EQK04_08160	COG2814	Major facilitator Superfamily
EQK04_08165	COG1033	growth of symbiont in host cell
EQK04_08165	COG2409	Drug exporters of the RND superfamily
EQK04_08170	COG0612	Peptidase, M16
EQK04_08175	COG0612	Peptidase, M16
EQK04_08185	COG1033	growth of symbiont in host cell
EQK04_08185	COG2409	Drug exporters of the RND superfamily
EQK04_08190	COG0300	oxidoreductase activity
EQK04_08205	COG1426	Protein conserved in bacteria
EQK04_08210	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EQK04_08215	COG1546	Belongs to the CinA family
EQK04_08215	COG1058	Belongs to the CinA family
EQK04_08220	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EQK04_08225	COG1418	mRNA catabolic process
EQK04_08230	COG1692	metallophosphoesterase
EQK04_08235	COG2359	stage V sporulation protein S
EQK04_08240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EQK04_08245	COG1063	alcohol dehydrogenase
EQK04_08250	COG0156	8-amino-7-oxononanoate synthase activity
EQK04_08255	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EQK04_08260	COG4550	Control of competence regulator ComK, YlbF/YmcA
EQK04_08270	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EQK04_08275	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EQK04_08295	COG1329	Transcriptional regulator
EQK04_08300	COG4195	phage-related replication protein
EQK04_08305	COG0457	Tetratricopeptide repeat
EQK04_08310	COG1404	Belongs to the peptidase S8 family
EQK04_08315	COG4195	phage-related replication protein
EQK04_08320	COG1764	response to oxidative stress
EQK04_08350	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EQK04_08355	COG1923	regulation of RNA biosynthetic process
EQK04_08370	COG1780	Probably involved in ribonucleotide reductase function
EQK04_08375	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EQK04_08380	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EQK04_08385	COG4112	unkown
EQK04_08395	COG0464	growth
EQK04_08400	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EQK04_08405	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EQK04_08410	COG0789	Transcriptional regulator
EQK04_08415	COG0174	glutamine synthetase
EQK04_08435	COG0457	Tetratricopeptide repeat
EQK04_08455	COG5444	nuclease activity
EQK04_08480	COG5646	InterPro IPR014922
EQK04_08500	COG0457	Tetratricopeptide repeat
EQK04_08510	COG3619	membrane
EQK04_08515	COG1793	dna ligase
EQK04_08515	COG3285	dna ligase
EQK04_08520	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EQK04_08525	COG4876	unkown
EQK04_08535	COG1959	2 iron, 2 sulfur cluster binding
EQK04_08540	COG0702	epimerase
EQK04_08550	COG0247	lactate metabolic process
EQK04_08555	COG1139	Iron-sulfur cluster binding protein
EQK04_08560	COG1556	Lactate utilization protein
EQK04_08575	COG2323	membrane
EQK04_08580	COG1309	transcriptional regulator
EQK04_08585	COG2124	cytochrome p450
EQK04_08585	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EQK04_08590	COG3591	Belongs to the peptidase S1B family
EQK04_08595	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EQK04_08600	COG3209	COG3209 Rhs family protein
EQK04_08605	COG1366	Belongs to the anti-sigma-factor antagonist family
EQK04_08620	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EQK04_08625	COG1388	LysM domain
EQK04_08630	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EQK04_08635	COG4224	UPF0291 protein
EQK04_08640	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EQK04_08650	COG3763	UPF0154 protein
EQK04_08660	COG0785	Cytochrome C biogenesis protein
EQK04_08665	COG4846	Membrane protein involved in cytochrome C biogenesis
EQK04_08675	COG0071	Belongs to the small heat shock protein (HSP20) family
EQK04_08690	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EQK04_08695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQK04_08715	COG0824	Thioesterase
EQK04_08725	COG4841	protein insertion into membrane
EQK04_08730	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EQK04_08735	COG1832	CoA-binding protein
EQK04_08740	COG0187	DNA topoisomerase II activity
EQK04_08745	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EQK04_08755	COG0738	Major facilitator superfamily
EQK04_08760	COG0473	3-isopropylmalate dehydrogenase activity
EQK04_08770	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EQK04_08775	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EQK04_08780	COG0640	Transcriptional regulator
EQK04_08790	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EQK04_08805	COG1309	transcriptional regulator
EQK04_08810	COG2249	NAD(P)H dehydrogenase (quinone) activity
EQK04_08815	COG1733	regulation of RNA biosynthetic process
EQK04_08820	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EQK04_08825	COG0251	oxidation-reduction process
EQK04_08865	COG0657	acetylesterase activity
EQK04_08875	COG2723	6-phospho-beta-galactosidase activity
EQK04_08880	COG1263	PTS System
EQK04_08880	COG2190	(PTS) system
EQK04_08880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQK04_08895	COG2205	protein histidine kinase activity
EQK04_08900	COG0745	RESPONSE REGULATOR receiver
EQK04_08910	COG3507	Belongs to the glycosyl hydrolase 43 family
EQK04_08915	COG1012	belongs to the aldehyde dehydrogenase family
EQK04_08920	COG1486	melibiose metabolic process
EQK04_08925	COG0395	ABC-type sugar transport system, permease component
EQK04_08930	COG1175	transmembrane transport
EQK04_08935	COG1653	transport
EQK04_08940	COG1609	Transcriptional regulator
EQK04_08945	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EQK04_08960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQK04_08995	COG5444	nuclease activity
EQK04_09000	COG1846	Transcriptional regulator
EQK04_09005	COG2814	Major facilitator Superfamily
EQK04_09015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQK04_09015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQK04_09015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQK04_09020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQK04_09020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQK04_09020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQK04_09025	COG1105	Belongs to the carbohydrate kinase PfkB family
EQK04_09035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EQK04_09055	COG1012	belongs to the aldehyde dehydrogenase family
EQK04_09060	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EQK04_09065	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EQK04_09070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EQK04_09075	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EQK04_09080	COG1024	Enoyl-CoA hydratase
EQK04_09085	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EQK04_09090	COG0511	ligase activity, forming carbon-carbon bonds
EQK04_09095	COG0439	Biotin carboxylase
EQK04_09100	COG0318	PFAM AMP-dependent synthetase and ligase
EQK04_09105	COG1960	acyl-CoA dehydrogenase activity
EQK04_09110	COG1649	PFAM Uncharacterised BCR, COG1649
EQK04_09120	COG1349	DNA-binding transcription factor activity
EQK04_09125	COG1942	4-Oxalocrotonate Tautomerase
EQK04_09135	COG3835	regulator
EQK04_09140	COG0277	FAD linked oxidase domain protein
EQK04_09145	COG0247	lactate metabolic process
EQK04_09165	COG0166	Belongs to the GPI family
EQK04_09170	COG2246	polysaccharide biosynthetic process
EQK04_09175	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EQK04_09180	COG0586	Pfam SNARE associated Golgi protein
EQK04_09185	COG1587	Uroporphyrinogen-III synthase
EQK04_09195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQK04_09210	COG0534	Mate efflux family protein
EQK04_09215	COG2027	D-alanyl-D-alanine carboxypeptidase
EQK04_09220	COG4677	pectinesterase activity
EQK04_09225	COG2323	membrane
EQK04_09230	COG2146	nitrite reductase [NAD(P)H] activity
EQK04_09235	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EQK04_09240	COG0243	molybdopterin cofactor binding
EQK04_09245	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EQK04_09250	COG2223	nitrite transmembrane transporter activity
EQK04_09255	COG0493	'glutamate synthase
EQK04_09260	COG0069	glutamate synthase activity
EQK04_09260	COG0070	glutamate synthase
EQK04_09260	COG0067	glutamate synthase
EQK04_09265	COG0583	DNA-binding transcription factor activity
EQK04_09275	COG1132	(ABC) transporter
EQK04_09280	COG0789	Transcriptional regulator
EQK04_09280	COG4978	Transcriptional regulator
EQK04_09285	COG0454	-acetyltransferase
EQK04_09290	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EQK04_09295	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EQK04_09300	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EQK04_09310	COG0243	molybdopterin cofactor binding
EQK04_09320	COG1070	Carbohydrate kinase
EQK04_09325	COG2115	Belongs to the xylose isomerase family
EQK04_09330	COG1940	carbohydrate kinase activity
EQK04_09340	COG2211	Major facilitator Superfamily
EQK04_09345	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQK04_09350	COG1994	Peptidase M50
EQK04_09370	COG1309	transcriptional regulator
EQK04_09375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EQK04_09380	COG3708	Transcriptional regulator
EQK04_09385	COG2378	regulation of single-species biofilm formation
EQK04_09395	COG0640	Transcriptional regulator
EQK04_09400	COG0531	amino acid
EQK04_09405	COG0741	lytic transglycosylase activity
EQK04_09410	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EQK04_09415	COG2079	MmgE PrpD family protein
EQK04_09420	COG0372	Belongs to the citrate synthase family
EQK04_09425	COG2322	membrane
EQK04_09435	COG1388	LysM domain
EQK04_09435	COG3584	3D domain protein
EQK04_09440	COG0514	ATP-dependent DNA helicase (RecQ)
EQK04_09450	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EQK04_09475	COG1012	belongs to the aldehyde dehydrogenase family
EQK04_09480	COG1657	PFAM Prenyltransferase squalene oxidase
EQK04_09485	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EQK04_09490	COG0385	Bile acid
EQK04_09495	COG0508	dehydrogenase complex catalyzes the overall conversion of
EQK04_09500	COG0567	Dehydrogenase, E1 component
EQK04_09505	COG4548	von Willebrand factor, type A
EQK04_09510	COG0714	Associated with various cellular activities
EQK04_09515	COG2032	superoxide dismutase activity
EQK04_09520	COG0791	NLP P60 protein
EQK04_09520	COG1388	LysM domain
EQK04_09525	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EQK04_09530	COG0534	Mate efflux family protein
EQK04_09535	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EQK04_09540	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EQK04_09550	COG2962	Rard protein
EQK04_09565	COG1733	regulation of RNA biosynthetic process
EQK04_09570	COG0778	Nitroreductase
EQK04_09580	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EQK04_09585	COG0793	Belongs to the peptidase S41A family
EQK04_09585	COG3409	Peptidoglycan-binding domain 1 protein
EQK04_09590	COG2226	methyltransferase
EQK04_09605	COG1876	peptidase activity
EQK04_09610	COG0813	purine-nucleoside phosphorylase activity
EQK04_09620	COG0671	phosphoesterase, PA-phosphatase related
EQK04_09635	COG4479	Belongs to the UPF0346 family
EQK04_09645	COG1509	lysine 2,3-aminomutase activity
EQK04_09650	COG3829	transcription factor binding
EQK04_09655	COG0463	Glycosyl transferase, family 2
EQK04_09670	COG4641	Protein conserved in bacteria
EQK04_09680	COG1086	Polysaccharide biosynthesis protein
EQK04_09685	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EQK04_09690	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EQK04_09695	COG1846	Transcriptional regulator
EQK04_09720	COG4698	Protein conserved in bacteria
EQK04_09725	COG2755	lipolytic protein G-D-S-L family
EQK04_09730	COG1999	signal sequence binding
EQK04_09745	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EQK04_09750	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EQK04_09755	COG1272	protein, Hemolysin III
EQK04_09760	COG0204	Acyl-transferase
EQK04_09765	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EQK04_09770	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EQK04_09775	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EQK04_09785	COG2521	methyltransferase
EQK04_09785	COG2136	Putative SAM-dependent methyltransferase
EQK04_09795	COG0129	dihydroxy-acid dehydratase activity
EQK04_09800	COG1413	lyase activity
EQK04_09805	COG1418	mRNA catabolic process
EQK04_09810	COG0386	Belongs to the glutathione peroxidase family
EQK04_09815	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EQK04_09820	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EQK04_09825	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EQK04_09835	COG1278	Cold shock
EQK04_09850	COG0328	RNA-DNA hybrid ribonuclease activity
EQK04_09855	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EQK04_09860	COG0328	RNA-DNA hybrid ribonuclease activity
EQK04_09870	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EQK04_09880	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EQK04_09890	COG1755	Isoprenylcysteine carboxyl methyltransferase
EQK04_09895	COG3424	synthase
EQK04_09900	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EQK04_09900	COG0456	acetyltransferase
EQK04_09905	COG0726	polysaccharide deacetylase
EQK04_09910	COG2233	PERMEase
EQK04_09915	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EQK04_09920	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EQK04_09925	COG1199	ATP-dependent helicase activity
EQK04_09935	COG0116	Belongs to the methyltransferase superfamily
EQK04_09945	COG3599	regulation of cell shape
EQK04_09950	COG4474	Belongs to the UPF0398 family
EQK04_09960	COG3359	exonuclease
EQK04_09965	COG1111	helicase
EQK04_09965	COG1205	dead DEAH box helicase
EQK04_09970	COG1902	pentaerythritol trinitrate reductase activity
EQK04_09975	COG2190	(PTS) system
EQK04_09980	COG0071	Belongs to the small heat shock protein (HSP20) family
EQK04_10010	COG3331	DNA recombination
EQK04_10015	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EQK04_10015	COG4499	WXG100 protein secretion system (Wss), protein YukC
EQK04_10025	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EQK04_10030	COG3935	DnaD domain protein
EQK04_10035	COG0017	Asparaginyl-tRNA synthetase
EQK04_10040	COG5353	protein conserved in bacteria
EQK04_10050	COG1199	ATP-dependent helicase activity
EQK04_10050	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EQK04_10055	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EQK04_10060	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EQK04_10065	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EQK04_10075	COG0617	tRNA 3'-terminal CCA addition
EQK04_10080	COG0438	transferase activity, transferring glycosyl groups
EQK04_10085	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EQK04_10090	COG1803	Methylglyoxal synthase
EQK04_10095	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EQK04_10100	COG1694	Mazg nucleotide pyrophosphohydrolase
EQK04_10105	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQK04_10115	COG4347	Protein of unknown function (DUF1405)
EQK04_10120	COG2010	Cytochrome c
EQK04_10120	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EQK04_10125	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EQK04_10130	COG0723	plastoquinol--plastocyanin reductase activity
EQK04_10140	COG5582	Belongs to the UPF0302 family
EQK04_10145	COG0457	Tetratricopeptide repeat
EQK04_10150	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EQK04_10155	COG0287	Prephenate dehydrogenase
EQK04_10160	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EQK04_10165	COG0159	tryptophan synthase activity
EQK04_10170	COG0133	tryptophan synthase activity
EQK04_10175	COG0135	phosphoribosylanthranilate isomerase activity
EQK04_10180	COG0134	indole-3-glycerol-phosphate synthase activity
EQK04_10185	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EQK04_10195	COG4401	Chorismate mutase type I
EQK04_10200	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EQK04_10205	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EQK04_10210	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EQK04_10215	COG0105	UTP biosynthetic process
EQK04_10220	COG0142	geranyltranstransferase activity
EQK04_10225	COG2226	methyltransferase
EQK04_10230	COG0142	geranyltranstransferase activity
EQK04_10240	COG0302	gtp cyclohydrolase
EQK04_10245	COG0776	regulation of translation
EQK04_10250	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EQK04_10265	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EQK04_10270	COG1160	GTP binding
EQK04_10300	COG1304	FMN binding
EQK04_10305	COG0539	negative regulation of cytoplasmic translation
EQK04_10310	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EQK04_10320	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EQK04_10325	COG2959	enzyme of heme biosynthesis
EQK04_10330	COG3409	Peptidoglycan-binding domain 1 protein
EQK04_10330	COG3773	Cell wall hydrolase
EQK04_10335	COG2339	peptidase activity
EQK04_10340	COG0492	ferredoxin-NADP+ reductase activity
EQK04_10345	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EQK04_10350	COG4862	establishment of competence for transformation
EQK04_10355	COG1408	metallophosphoesterase
EQK04_10365	COG1388	LysM domain
EQK04_10370	COG1266	CAAX protease self-immunity
EQK04_10375	COG0514	ATP-dependent DNA helicase (RecQ)
EQK04_10380	COG4955	Helix-turn-helix domain
EQK04_10385	COG1141	Ferredoxin
EQK04_10390	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EQK04_10395	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EQK04_10410	COG1595	DNA-templated transcription, initiation
EQK04_10415	COG5002	protein histidine kinase activity
EQK04_10420	COG0745	RESPONSE REGULATOR receiver
EQK04_10425	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EQK04_10430	COG1333	cytochrome c biogenesis protein
EQK04_10435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQK04_10440	COG1187	pseudouridine synthase activity
EQK04_10445	COG0700	Nucleoside recognition
EQK04_10450	COG2715	membrane protein required for spore maturation
EQK04_10455	COG1686	Belongs to the peptidase S11 family
EQK04_10465	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EQK04_10470	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EQK04_10480	COG1547	Domain of unknown function (DUF309)
EQK04_10490	COG0456	acetyltransferase
EQK04_10495	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EQK04_10500	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EQK04_10500	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EQK04_10505	COG0307	riboflavin synthase, alpha
EQK04_10530	COG2814	Major facilitator Superfamily
EQK04_10535	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EQK04_10540	COG4086	secreted protein
EQK04_10545	COG0019	diaminopimelate decarboxylase activity
EQK04_10550	COG0697	spore germination
EQK04_10565	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EQK04_10585	COG1191	sigma factor activity
EQK04_10590	COG2172	sigma factor antagonist activity
EQK04_10600	COG1686	Belongs to the peptidase S11 family
EQK04_10605	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EQK04_10610	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EQK04_10615	COG4974	Belongs to the 'phage' integrase family
EQK04_10625	COG0735	belongs to the Fur family
EQK04_10630	COG1300	Membrane
EQK04_10635	COG1404	Belongs to the peptidase S8 family
EQK04_10650	COG2153	protein acetylation
EQK04_10655	COG1379	DNA repair
EQK04_10660	COG0494	nUDIX hydrolase
EQK04_10665	COG0667	Aldo Keto reductase
EQK04_10675	COG1073	alpha beta
EQK04_10680	COG0457	Tetratricopeptide repeat
EQK04_10690	COG4918	Iron-sulphur cluster biosynthesis
EQK04_10695	COG4305	rare lipoprotein A
EQK04_10700	COG0456	acetyltransferase
EQK04_10700	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EQK04_10705	COG0456	acetyltransferase
EQK04_10715	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EQK04_10725	COG2211	Major facilitator Superfamily
EQK04_10730	COG1072	(Pantothenic acid kinase))
EQK04_10735	COG0446	pyridine nucleotide-disulphide oxidoreductase
EQK04_10745	COG0300	oxidoreductase activity
EQK04_10750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EQK04_10755	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EQK04_10770	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EQK04_10775	COG4187	Peptidase family M20/M25/M40
EQK04_10780	COG1902	pentaerythritol trinitrate reductase activity
EQK04_10785	COG0596	Alpha beta hydrolase
EQK04_10790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQK04_10800	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EQK04_10805	COG2188	Transcriptional regulator
EQK04_10810	COG2723	6-phospho-beta-galactosidase activity
EQK04_10815	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQK04_10820	COG1447	Phosphotransferase system cellobiose-specific component IIA
EQK04_10825	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQK04_10835	COG1028	Short-chain dehydrogenase reductase Sdr
EQK04_10845	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EQK04_10850	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EQK04_10860	COG0706	membrane insertase activity
EQK04_10865	COG0835	chemotaxis
EQK04_10870	COG2195	Cleaves the N-terminal amino acid of tripeptides
EQK04_10875	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EQK04_10880	COG0346	lactoylglutathione lyase activity
EQK04_10885	COG1376	ErfK ybiS ycfS ynhG family protein
EQK04_10890	COG4129	membrane
EQK04_10895	COG1126	abc transporter atp-binding protein
EQK04_10900	COG0765	amino acid transport
EQK04_10905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQK04_10915	COG1597	lipid kinase activity
EQK04_10925	COG0508	dehydrogenase complex catalyzes the overall conversion of
EQK04_10930	COG0022	dehydrogenase e1 component
EQK04_10935	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EQK04_10940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EQK04_10945	COG3426	butyrate kinase activity
EQK04_10950	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EQK04_10955	COG0280	phosphate acetyltransferase
EQK04_10960	COG3290	protein histidine kinase activity
EQK04_10960	COG3829	transcription factor binding
EQK04_10970	COG0584	glycerophosphoryl diester phosphodiesterase
EQK04_10975	COG0457	Tetratricopeptide repeat
EQK04_10980	COG0745	RESPONSE REGULATOR receiver
EQK04_10985	COG0750	zinc metalloprotease
EQK04_10990	COG0497	DNA recombination
EQK04_10995	COG1438	arginine binding
EQK04_11000	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EQK04_11005	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EQK04_11010	COG0142	geranyltranstransferase activity
EQK04_11015	COG1722	exodeoxyribonuclease VII activity
EQK04_11020	COG1570	exodeoxyribonuclease VII activity
EQK04_11025	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EQK04_11030	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EQK04_11035	COG1302	Protein conserved in bacteria
EQK04_11040	COG0439	Biotin carboxylase
EQK04_11045	COG0511	ligase activity, forming carbon-carbon bonds
EQK04_11085	COG3854	ATPases associated with a variety of cellular activities
EQK04_11095	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EQK04_11100	COG0006	proline dipeptidase activity
EQK04_11105	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EQK04_11115	COG3872	metal-dependent enzyme
EQK04_11125	COG1752	Esterase of the alpha-beta hydrolase superfamily
EQK04_11130	COG1321	iron dependent repressor
EQK04_11135	COG0095	Lipoate-protein ligase
EQK04_11140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EQK04_11145	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EQK04_11150	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EQK04_11155	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EQK04_11160	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EQK04_11185	COG0681	Belongs to the peptidase S26 family
EQK04_11220	COG4970	Tfp pilus assembly protein FimT
EQK04_11225	COG4537	Required for transformation and DNA binding
EQK04_11230	COG1459	type II secretion system
EQK04_11235	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EQK04_11240	COG1366	Belongs to the anti-sigma-factor antagonist family
EQK04_11250	COG1393	Belongs to the ArsC family
EQK04_11260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EQK04_11270	COG0011	TIGRFAM Protein of
EQK04_11275	COG2814	Major facilitator Superfamily
EQK04_11285	COG2866	Carboxypeptidase
EQK04_11290	COG1368	sulfuric ester hydrolase activity
EQK04_11295	COG1940	carbohydrate kinase activity
EQK04_11300	COG4483	Protein conserved in bacteria
EQK04_11305	COG0457	Tetratricopeptide repeat
EQK04_11305	COG0705	Rhomboid family
EQK04_11315	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EQK04_11320	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EQK04_11335	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EQK04_11340	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EQK04_11345	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EQK04_11350	COG0581	inorganic phosphate transmembrane transporter activity
EQK04_11355	COG0573	inorganic phosphate transmembrane transporter activity
EQK04_11360	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EQK04_11370	COG0477	Major facilitator Superfamily
EQK04_11375	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EQK04_11380	COG2839	Protein conserved in bacteria
EQK04_11385	COG5521	maltodextrose utilization protein MalA
EQK04_11390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EQK04_11395	COG1388	LysM domain
EQK04_11400	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EQK04_11405	COG4709	membrane
EQK04_11410	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
EQK04_11415	COG1940	carbohydrate kinase activity
EQK04_11420	COG0735	belongs to the Fur family
EQK04_11425	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EQK04_11430	COG1121	(ABC) transporter
EQK04_11435	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQK04_11450	COG0513	Belongs to the DEAD box helicase family
EQK04_11460	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EQK04_11465	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EQK04_11470	COG2384	SAM-dependent methyltransferase
EQK04_11475	COG2010	Cytochrome c
EQK04_11480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EQK04_11485	COG0358	DNA primase activity
EQK04_11490	COG1671	Belongs to the UPF0178 family
EQK04_11495	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EQK04_11500	COG0517	IMP dehydrogenase activity
EQK04_11505	COG0751	glycine-tRNA ligase activity
EQK04_11510	COG0752	glycyl-tRNA synthetase alpha subunit
EQK04_11515	COG1381	Involved in DNA repair and RecF pathway recombination
EQK04_11525	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EQK04_11530	COG0295	cytidine deaminase activity
EQK04_11535	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EQK04_11540	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EQK04_11545	COG1480	7TM receptor with intracellular HD hydrolase
EQK04_11550	COG1702	phosphate starvation-inducible protein PhoH
EQK04_11555	COG0561	phosphatase activity
EQK04_11570	COG4864	UPF0365 protein
EQK04_11575	COG1030	water channel activity
EQK04_11580	COG1610	YqeY-like protein
EQK04_11590	COG1283	sodium-dependent phosphate transmembrane transporter activity
EQK04_11595	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EQK04_11600	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EQK04_11605	COG2264	protein methyltransferase activity
EQK04_11610	COG0484	heat shock protein binding
EQK04_11615	COG0443	Heat shock 70 kDa protein
EQK04_11620	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EQK04_11625	COG1420	regulation of RNA biosynthetic process
EQK04_11630	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EQK04_11635	COG0481	GTPase activity
EQK04_11645	COG0860	N-Acetylmuramoyl-L-alanine amidase
EQK04_11650	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EQK04_11655	COG0268	Binds directly to 16S ribosomal RNA
EQK04_11660	COG1466	dna polymerase III delta subunit
EQK04_11670	COG2333	competence protein COMEC
EQK04_11670	COG0658	competence protein
EQK04_11675	COG2131	deaminase
EQK04_11680	COG1555	photosystem II stabilization
EQK04_11680	COG1596	polysaccharide export
EQK04_11685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EQK04_11690	COG2226	methyltransferase
EQK04_11695	COG0799	negative regulation of ribosome biogenesis
EQK04_11700	COG1713	HD superfamily hydrolase involved in NAD metabolism
EQK04_11705	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EQK04_11710	COG1534	Rna-binding protein
EQK04_11715	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EQK04_11720	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EQK04_11725	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EQK04_11735	COG2755	lipolytic protein G-D-S-L family
EQK04_11745	COG0457	Tetratricopeptide repeat
EQK04_11775	COG0726	polysaccharide deacetylase
EQK04_11810	COG1131	(ABC) transporter
EQK04_11840	COG2160	L-arabinose isomerase activity
EQK04_11855	COG1609	Transcriptional regulator
EQK04_11865	COG1846	Transcriptional regulator
EQK04_11875	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EQK04_11880	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EQK04_11885	COG1733	regulation of RNA biosynthetic process
EQK04_11955	COG2602	Beta-lactamase
EQK04_11960	COG1960	acyl-CoA dehydrogenase activity
EQK04_11965	COG1126	abc transporter atp-binding protein
EQK04_11970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQK04_11975	COG0765	amino acid transport
EQK04_11985	COG3546	catalase activity
EQK04_11990	COG1063	alcohol dehydrogenase
EQK04_12000	COG1028	Short-chain dehydrogenase reductase Sdr
EQK04_12010	COG1115	amino acid carrier protein
EQK04_12015	COG0583	DNA-binding transcription factor activity
EQK04_12020	COG0842	Transport permease protein
EQK04_12025	COG0842	Transport permease protein
EQK04_12025	COG1511	domain protein
EQK04_12030	COG1131	(ABC) transporter
EQK04_12035	COG1063	alcohol dehydrogenase
EQK04_12040	COG2226	methyltransferase
EQK04_12060	COG0626	cystathionine gamma-synthase activity
EQK04_12065	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EQK04_12070	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EQK04_12075	COG2226	methyltransferase
EQK04_12090	COG0768	penicillin binding
EQK04_12095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EQK04_12100	COG0572	uridine kinase
EQK04_12115	COG4122	O-methyltransferase activity
EQK04_12120	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EQK04_12125	COG0183	Belongs to the thiolase family
EQK04_12130	COG0318	PFAM AMP-dependent synthetase and ligase
EQK04_12135	COG1268	BioY protein
EQK04_12140	COG3906	Belongs to the UPF0473 family
EQK04_12145	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EQK04_12150	COG4472	Bacterial protein of unknown function (DUF965)
EQK04_12155	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EQK04_12160	COG0628	permease
EQK04_12165	COG1126	abc transporter atp-binding protein
EQK04_12170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQK04_12175	COG0765	amino acid transport
EQK04_12180	COG0765	amino acid transport
EQK04_12195	COG3881	PFAM PRC-barrel domain
EQK04_12200	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EQK04_12205	COG0457	Tetratricopeptide repeat
EQK04_12210	COG0482	sulfurtransferase activity
EQK04_12215	COG1104	cysteine desulfurase activity
EQK04_12220	COG1959	2 iron, 2 sulfur cluster binding
EQK04_12225	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EQK04_12230	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EQK04_12245	COG0124	histidyl-tRNA synthetase
EQK04_12250	COG3103	Sh3 type 3 domain protein
EQK04_12250	COG0860	N-Acetylmuramoyl-L-alanine amidase
EQK04_12250	COG4991	sh3 domain protein
EQK04_12255	COG1490	D-aminoacyl-tRNA deacylase activity
EQK04_12260	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EQK04_12265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EQK04_12270	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EQK04_12270	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EQK04_12275	COG5416	Lipopolysaccharide assembly protein A domain
EQK04_12280	COG0490	domain, Protein
EQK04_12285	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EQK04_12285	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EQK04_12295	COG2244	polysaccharide biosynthetic process
EQK04_12300	COG2323	membrane
EQK04_12310	COG1862	Preprotein translocase
EQK04_12315	COG0343	queuine tRNA-ribosyltransferase activity
EQK04_12320	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EQK04_12330	COG2255	four-way junction helicase activity
EQK04_12335	COG0632	four-way junction helicase activity
EQK04_12345	COG2112	serine threonine protein kinase
EQK04_12355	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EQK04_12370	COG1388	LysM domain
EQK04_12375	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EQK04_12380	COG0157	Belongs to the NadC ModD family
EQK04_12385	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EQK04_12390	COG1104	cysteine desulfurase activity
EQK04_12395	COG1827	regulation of RNA biosynthetic process
EQK04_12400	COG0077	Prephenate dehydratase
EQK04_12405	COG4492	Belongs to the UPF0735 family
EQK04_12410	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EQK04_12415	COG3290	protein histidine kinase activity
EQK04_12420	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EQK04_12425	COG2868	ribosomal protein
EQK04_12430	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EQK04_12435	COG1994	Peptidase M50
EQK04_12440	COG0739	heme binding
EQK04_12445	COG2894	cell division
EQK04_12450	COG0850	regulation of cytokinetic process
EQK04_12455	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EQK04_12465	COG1077	Cell shape determining protein MreB Mrl
EQK04_12470	COG2003	Belongs to the UPF0758 family
EQK04_12475	COG0424	maF-like protein
EQK04_12485	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EQK04_12490	COG0285	dihydrofolate synthase activity
EQK04_12495	COG0525	valine-tRNA ligase activity
EQK04_12505	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EQK04_12510	COG1388	LysM domain
EQK04_12515	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EQK04_12520	COG0113	porphobilinogen synthase activity
EQK04_12525	COG1587	Uroporphyrinogen-III synthase
EQK04_12530	COG0181	hydroxymethylbilane synthase activity
EQK04_12535	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EQK04_12540	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EQK04_12560	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EQK04_12565	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EQK04_12570	COG0470	DNA polymerase III
EQK04_12570	COG1067	ATP-dependent peptidase activity
EQK04_12575	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EQK04_12580	COG0544	peptidyl-prolyl cis-trans isomerase activity
EQK04_12585	COG0457	Tetratricopeptide repeat
EQK04_12585	COG1477	protein flavinylation
EQK04_12590	COG0066	3-isopropylmalate dehydratase activity
EQK04_12595	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EQK04_12600	COG0473	3-isopropylmalate dehydrogenase activity
EQK04_12605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EQK04_12610	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EQK04_12615	COG0440	acetolactate synthase activity
EQK04_12620	COG0028	Belongs to the TPP enzyme family
EQK04_12625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EQK04_12630	COG2706	6-phosphogluconolactonase activity
EQK04_12635	COG3339	Conserved Protein
EQK04_12640	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EQK04_12645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EQK04_12650	COG1696	Membrane protein involved in D-alanine export
EQK04_12655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EQK04_12690	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EQK04_12695	COG5444	nuclease activity
EQK04_12710	COG0622	Phosphoesterase
EQK04_12715	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EQK04_12720	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EQK04_12725	COG5401	PFAM Sporulation and spore germination
EQK04_12730	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EQK04_12735	COG1846	Transcriptional regulator
EQK04_12740	COG2197	response regulator
EQK04_12765	COG3409	Peptidoglycan-binding domain 1 protein
EQK04_12765	COG5632	N-Acetylmuramoyl-L-alanine amidase
EQK04_12770	COG4824	toxin secretion phage lysis holin
EQK04_12800	COG1705	Flagellar rod assembly protein muramidase FlgJ
EQK04_12880	COG1802	Transcriptional regulator
EQK04_12880	COG4626	Terminase
EQK04_12920	COG0582	viral genome integration into host DNA
EQK04_12925	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EQK04_13005	COG2197	response regulator
EQK04_13010	COG2851	Citrate transporter
EQK04_13015	COG0583	DNA-binding transcription factor activity
EQK04_13020	COG2828	Protein conserved in bacteria
EQK04_13030	COG0824	Thioesterase
EQK04_13035	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EQK04_13040	COG1053	succinate dehydrogenase
EQK04_13045	COG2009	succinate dehydrogenase
EQK04_13050	COG1719	4-vinyl reductase, 4VR
EQK04_13060	COG0527	aspartate kinase activity
EQK04_13065	COG0322	excinuclease ABC activity
EQK04_13070	COG3118	belongs to the thioredoxin family
EQK04_13075	COG3534	alpha-L-arabinofuranosidase
EQK04_13080	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EQK04_13085	COG2086	electron transfer activity
EQK04_13090	COG1024	Enoyl-CoA hydratase
EQK04_13095	COG1309	transcriptional regulator
EQK04_13100	COG0318	PFAM AMP-dependent synthetase and ligase
EQK04_13110	COG3766	membrane
EQK04_13115	COG1193	negative regulation of DNA recombination
EQK04_13120	COG1796	DNA polymerase
EQK04_13120	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EQK04_13125	COG1286	toxin biosynthetic process
EQK04_13130	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EQK04_13135	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EQK04_13140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQK04_13140	COG0072	phenylalanine-tRNA ligase activity
EQK04_13145	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EQK04_13150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EQK04_13160	COG1966	Carbon starvation protein
EQK04_13165	COG1363	Peptidase, m42
EQK04_13175	COG3326	Membrane
EQK04_13180	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EQK04_13185	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EQK04_13190	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EQK04_13200	COG1011	Hydrolase
EQK04_13210	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EQK04_13225	COG0398	Pfam SNARE associated Golgi protein
EQK04_13230	COG1484	DNA-dependent DNA replication
EQK04_13235	COG3611	Membrane attachment protein
EQK04_13240	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EQK04_13250	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EQK04_13255	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EQK04_13260	COG0237	dephospho-CoA kinase activity
EQK04_13265	COG1971	Probably functions as a manganese efflux pump
EQK04_13270	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EQK04_13275	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EQK04_13275	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EQK04_13280	COG5002	protein histidine kinase activity
EQK04_13285	COG0745	RESPONSE REGULATOR receiver
EQK04_13290	COG0039	L-malate dehydrogenase activity
EQK04_13295	COG0538	isocitrate dehydrogenase activity
EQK04_13300	COG0372	Belongs to the citrate synthase family
EQK04_13305	COG2707	UPF0756 membrane protein
EQK04_13310	COG0628	permease
EQK04_13315	COG3030	protein affecting phage T7 exclusion by the F plasmid
EQK04_13325	COG0205	6-phosphofructokinase activity
EQK04_13330	COG0825	malonyl-CoA metabolic process
EQK04_13335	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EQK04_13340	COG0281	malic enzyme
EQK04_13345	COG0587	DNA-directed DNA polymerase activity
EQK04_13365	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EQK04_13380	COG4109	DRTGG domain
EQK04_13385	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EQK04_13390	COG1028	Short-chain dehydrogenase reductase Sdr
EQK04_13400	COG0165	Argininosuccinate lyase
EQK04_13405	COG0137	argininosuccinate synthase activity
EQK04_13410	COG0521	Mo-molybdopterin cofactor biosynthetic process
EQK04_13415	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EQK04_13420	COG0827	DNA restriction-modification system
EQK04_13425	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EQK04_13430	COG3874	Sporulation protein YtfJ
EQK04_13440	COG1714	RDD family
EQK04_13445	COG0616	signal peptide processing
EQK04_13450	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EQK04_13460	COG3239	Fatty acid desaturase
EQK04_13465	COG4585	Histidine kinase
EQK04_13470	COG2197	response regulator
EQK04_13475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQK04_13480	COG0745	RESPONSE REGULATOR receiver
EQK04_13485	COG2205	protein histidine kinase activity
EQK04_13490	COG1136	(ABC) transporter
EQK04_13495	COG0577	efflux transmembrane transporter activity
EQK04_13500	COG0402	S-adenosylhomocysteine deaminase activity
EQK04_13505	COG2249	NAD(P)H dehydrogenase (quinone) activity
EQK04_13520	COG1279	arginine transmembrane transporter activity
EQK04_13525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EQK04_13535	COG0301	tRNA thio-modification
EQK04_13540	COG1104	cysteine desulfurase activity
EQK04_13545	COG1114	Component of the transport system for branched-chain amino acids
EQK04_13550	COG1114	Component of the transport system for branched-chain amino acids
EQK04_13555	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EQK04_13560	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EQK04_13565	COG1309	transcriptional regulator
EQK04_13570	COG1956	GAF domain-containing protein
EQK04_13575	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EQK04_13585	COG1335	isochorismatase
EQK04_13595	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EQK04_13600	COG2329	Antibiotic biosynthesis monooxygenase
EQK04_13605	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EQK04_13610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EQK04_13615	COG0454	-acetyltransferase
EQK04_13620	COG0517	IMP dehydrogenase activity
EQK04_13625	COG0123	including yeast histone deacetylase and acetoin utilization protein
EQK04_13630	COG1609	Transcriptional regulator
EQK04_13635	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EQK04_13635	COG1605	Chorismate mutase
EQK04_13640	COG3118	belongs to the thioredoxin family
EQK04_13645	COG4980	gas vesicle protein
EQK04_13650	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EQK04_13655	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EQK04_13660	COG1674	ftsk spoiiie
EQK04_13665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQK04_13670	COG4848	Belongs to the UPF0354 family
EQK04_13675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQK04_13690	COG1363	Peptidase, m42
EQK04_13695	COG5584	Small secreted protein
EQK04_13700	COG0281	malic enzyme
EQK04_13705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EQK04_13710	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EQK04_13720	COG0510	thiamine kinase activity
EQK04_13725	COG1597	lipid kinase activity
EQK04_13735	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EQK04_13740	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EQK04_13745	COG3340	Belongs to the peptidase S51 family
EQK04_13750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EQK04_13755	COG2252	PERMEase
EQK04_13760	COG1349	DNA-binding transcription factor activity
EQK04_13765	COG1187	pseudouridine synthase activity
EQK04_13770	COG2244	polysaccharide biosynthetic process
EQK04_13775	COG2081	HI0933 family
EQK04_13785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EQK04_13790	COG3196	Protein conserved in bacteria
EQK04_13800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EQK04_13805	COG5578	integral membrane protein
EQK04_13810	COG0673	inositol 2-dehydrogenase activity
EQK04_13815	COG1653	transport
EQK04_13820	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EQK04_13825	COG4209	transmembrane transport
EQK04_13830	COG2207	Transcriptional regulator
EQK04_13835	COG1733	regulation of RNA biosynthetic process
EQK04_13840	COG2814	Major facilitator Superfamily
EQK04_13845	COG0656	L-ascorbic acid biosynthetic process
EQK04_13850	COG1653	transport
EQK04_13855	COG0395	ABC-type sugar transport system, permease component
EQK04_13860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EQK04_13865	COG1073	alpha beta
EQK04_13870	COG0495	leucyl-tRNA aminoacylation
EQK04_13880	COG2202	Pas domain
EQK04_13880	COG1366	Belongs to the anti-sigma-factor antagonist family
EQK04_13885	COG2433	Pfam Transposase IS66
EQK04_13890	COG0577	efflux transmembrane transporter activity
EQK04_13895	COG1136	(ABC) transporter
EQK04_13905	COG1131	(ABC) transporter
EQK04_13910	COG1725	Transcriptional regulator
EQK04_13930	COG1242	4 iron, 4 sulfur cluster binding
EQK04_13935	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EQK04_13940	COG4326	sporulation control protein
EQK04_13950	COG2267	carboxylic ester hydrolase activity
EQK04_13955	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EQK04_13960	COG0367	asparagine synthase
EQK04_13965	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EQK04_13970	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EQK04_13980	COG1506	peptidase
EQK04_13985	COG1233	COG1233 Phytoene dehydrogenase and related
EQK04_14005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EQK04_14010	COG1116	anion transmembrane transporter activity
EQK04_14015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EQK04_14020	COG0494	nUDIX hydrolase
EQK04_14025	COG2310	stress, protein
EQK04_14040	COG4824	toxin secretion phage lysis holin
EQK04_14050	COG0783	Belongs to the Dps family
EQK04_14065	COG1854	S-ribosylhomocysteine lyase activity
EQK04_14070	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EQK04_14075	COG0288	reversible hydration of carbon dioxide
EQK04_14080	COG0803	Belongs to the bacterial solute-binding protein 9 family
EQK04_14080	COG3443	Belongs to the bacterial solute-binding protein 9 family
EQK04_14095	COG1271	oxidase subunit
EQK04_14100	COG1294	oxidase, subunit
EQK04_14115	COG4948	Mandelate Racemase Muconate Lactonizing
EQK04_14120	COG0318	PFAM AMP-dependent synthetase and ligase
EQK04_14125	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EQK04_14130	COG0596	Alpha beta hydrolase
EQK04_14135	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EQK04_14140	COG1169	isochorismate synthase
EQK04_14145	COG1575	Belongs to the MenA family. Type 1 subfamily
EQK04_14150	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EQK04_14280	COG3859	Proton-coupled thiamine transporter YuaJ
EQK04_14290	COG1247	-acetyltransferase
EQK04_14295	COG3339	Conserved Protein
EQK04_14300	COG0772	Belongs to the SEDS family
EQK04_14305	COG0772	Belongs to the SEDS family
EQK04_14310	COG2268	Band 7 protein
EQK04_14315	COG1585	Membrane protein implicated in regulation of membrane protease activity
EQK04_14320	COG2318	DinB family
EQK04_14325	COG1454	alcohol dehydrogenase
EQK04_14330	COG1012	belongs to the aldehyde dehydrogenase family
EQK04_14335	COG1510	regulation of RNA biosynthetic process
EQK04_14350	COG5632	N-Acetylmuramoyl-L-alanine amidase
EQK04_14350	COG3409	Peptidoglycan-binding domain 1 protein
EQK04_14405	COG3778	Protein conserved in bacteria
EQK04_14410	COG3299	homolog of phage Mu protein gp47
EQK04_14415	COG3628	GPW Gp25 family protein
EQK04_14425	COG4193	domain, Protein
EQK04_14430	COG1652	LysM domain
EQK04_14435	COG5280	Phage tail tape measure protein TP901
EQK04_14435	COG3953	SLT domain
EQK04_14435	COG3953	SLT domain
EQK04_14435	COG5280	Phage tail tape measure protein TP901
EQK04_14490	COG4653	Phage capsid family
EQK04_14495	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EQK04_14500	COG5518	Phage portal protein
EQK04_14505	COG1783	phage Terminase large subunit
EQK04_14510	COG5484	DNA packaging
EQK04_14515	COG1595	DNA-templated transcription, initiation
EQK04_14525	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
EQK04_14540	COG1396	sequence-specific DNA binding
EQK04_14550	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EQK04_14565	COG0628	permease
EQK04_14575	COG0673	inositol 2-dehydrogenase activity
EQK04_14580	COG0693	protein deglycase activity
EQK04_14585	COG0840	transmembrane signaling receptor activity
EQK04_14590	COG0840	transmembrane signaling receptor activity
EQK04_14595	COG0840	transmembrane signaling receptor activity
EQK04_14600	COG0840	transmembrane signaling receptor activity
EQK04_14615	COG2070	2-Nitropropane dioxygenase
EQK04_14620	COG0432	Pfam Uncharacterised protein family UPF0047
EQK04_14625	COG1253	flavin adenine dinucleotide binding
EQK04_14630	COG2738	Putative neutral zinc metallopeptidase
EQK04_14640	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EQK04_14655	COG0166	Belongs to the GPI family
EQK04_14660	COG1979	alcohol dehydrogenase
EQK04_14665	COG1979	alcohol dehydrogenase
EQK04_14670	COG2155	Conserved Protein
EQK04_14675	COG1098	S1 RNA binding domain
EQK04_14680	COG0436	Aminotransferase
EQK04_14685	COG1522	sequence-specific DNA binding
EQK04_14690	COG2267	carboxylic ester hydrolase activity
EQK04_14700	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EQK04_14705	COG2205	protein histidine kinase activity
EQK04_14715	COG5018	Exonuclease
EQK04_14720	COG2814	Major facilitator Superfamily
EQK04_14725	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EQK04_14730	COG3011	Protein conserved in bacteria
EQK04_14740	COG3290	protein histidine kinase activity
EQK04_14745	COG4565	transcriptional regulatory protein
EQK04_14770	COG3493	citrate carrier protein
EQK04_14780	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EQK04_14780	COG2111	Na H antiporter
EQK04_14785	COG2111	Na H antiporter
EQK04_14790	COG1006	Multisubunit Na H antiporter MnhC subunit
EQK04_14795	COG0651	ATP synthesis coupled electron transport
EQK04_14800	COG1863	multisubunit Na H antiporter MnhE subunit
EQK04_14805	COG2212	antiporter activity
EQK04_14810	COG1320	monovalent cation:proton antiporter activity
EQK04_14815	COG2050	protein possibly involved in aromatic compounds catabolism
EQK04_14820	COG2197	response regulator
EQK04_14825	COG4585	Histidine kinase
EQK04_14835	COG0142	geranyltranstransferase activity
EQK04_14850	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EQK04_14855	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EQK04_14860	COG1335	isochorismatase
EQK04_14865	COG5506	Protein of unknown function (DUF1694)
EQK04_14885	COG0628	permease
EQK04_14900	COG1418	mRNA catabolic process
EQK04_14905	COG1028	Short-chain dehydrogenase reductase Sdr
EQK04_14915	COG1511	domain protein
EQK04_14920	COG1674	ftsk spoiiie
EQK04_14920	COG0433	COG0433 Predicted ATPase
EQK04_14925	COG4499	WXG100 protein secretion system (Wss), protein YukC
EQK04_14930	COG5417	Belongs to the EsaB family
EQK04_14935	COG4842	Belongs to the WXG100 family
EQK04_14940	COG2508	Transcriptional regulator
EQK04_14940	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EQK04_14945	COG0686	Belongs to the AlaDH PNT family
EQK04_14950	COG1268	BioY protein
EQK04_14955	COG2056	Na+-H+ antiporter family
EQK04_14960	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EQK04_14965	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EQK04_14970	COG3584	3D domain protein
EQK04_14980	COG1252	NADH dehydrogenase
EQK04_14985	COG0492	ferredoxin-NADP+ reductase activity
EQK04_15000	COG0789	Transcriptional regulator
EQK04_15005	COG5504	Zn-dependent protease
EQK04_15010	COG0316	Belongs to the HesB IscA family
EQK04_15015	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EQK04_15020	COG4844	belongs to the
EQK04_15025	COG1252	NADH dehydrogenase
EQK04_15035	COG4837	Protein of unknown function (DUF1462)
EQK04_15040	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EQK04_15045	COG0823	Involved in the tonB-independent uptake of proteins
EQK04_15045	COG4946	Tricorn protease homolog
EQK04_15045	COG1506	peptidase
EQK04_15050	COG0083	homoserine kinase activity
EQK04_15055	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EQK04_15060	COG0460	homoserine dehydrogenase
EQK04_15065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EQK04_15070	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EQK04_15075	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EQK04_15095	COG0647	UMP catabolic process
EQK04_15100	COG2445	Protein of unknown function DUF86
EQK04_15105	COG4470	Protein conserved in bacteria
EQK04_15115	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EQK04_15120	COG0739	heme binding
EQK04_15140	COG3377	Domain of unknown function (DUF1805)
EQK04_15145	COG0737	Belongs to the 5'-nucleotidase family
EQK04_15150	COG1801	Protein of unknown function DUF72
EQK04_15155	COG2508	Transcriptional regulator
EQK04_15160	COG2140	Oxalate decarboxylase
EQK04_15165	COG2814	Major facilitator Superfamily
EQK04_15170	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EQK04_15175	COG2356	endonuclease I
EQK04_15185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQK04_15190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQK04_15195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQK04_15215	COG0642	Histidine kinase
EQK04_15215	COG5002	protein histidine kinase activity
EQK04_15220	COG0745	RESPONSE REGULATOR receiver
EQK04_15225	COG2311	Membrane
EQK04_15235	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EQK04_15245	COG1309	transcriptional regulator
EQK04_15260	COG0719	Fe-S assembly protein
EQK04_15265	COG0822	iron-sulfur transferase activity
EQK04_15270	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EQK04_15275	COG0719	Fe-S assembly protein
EQK04_15280	COG0396	ATPase activity
EQK04_15285	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EQK04_15290	COG1464	Belongs to the NlpA lipoprotein family
EQK04_15295	COG2011	ABC-type metal ion transport system permease component
EQK04_15300	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EQK04_15310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQK04_15315	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EQK04_15325	COG0509	glycine decarboxylation via glycine cleavage system
EQK04_15330	COG1393	Belongs to the ArsC family
EQK04_15335	COG1960	acyl-CoA dehydrogenase activity
EQK04_15340	COG0183	Belongs to the thiolase family
EQK04_15345	COG1024	Enoyl-CoA hydratase
EQK04_15345	COG1250	3-hydroxyacyl-CoA dehydrogenase
EQK04_15360	COG5577	PFAM Coat F domain
EQK04_15370	COG1120	ATPase activity
EQK04_15380	COG1028	Short-chain dehydrogenase reductase Sdr
EQK04_15390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EQK04_15395	COG0745	RESPONSE REGULATOR receiver
EQK04_15400	COG2205	protein histidine kinase activity
EQK04_15400	COG2770	Histidine kinase
EQK04_15405	COG1309	transcriptional regulator
EQK04_15410	COG0114	fumarate hydratase activity
EQK04_15420	COG0697	spore germination
EQK04_15425	COG0814	amino acid
EQK04_15440	COG2197	response regulator
EQK04_15445	COG4585	Histidine kinase
EQK04_15450	COG4758	membrane
EQK04_15460	COG1842	Phage shock protein A
EQK04_15465	COG4758	membrane
EQK04_15470	COG2096	Adenosyltransferase
EQK04_15475	COG1028	Short-chain dehydrogenase reductase Sdr
EQK04_15480	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EQK04_15505	COG1454	alcohol dehydrogenase
EQK04_15510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EQK04_15515	COG1120	ATPase activity
EQK04_15520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQK04_15525	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQK04_15535	COG2721	sulfolactate sulfo-lyase activity
EQK04_15540	COG0246	Mannitol dehydrogenase
EQK04_15545	COG1609	Transcriptional regulator
EQK04_15550	COG1904	glucuronate isomerase
EQK04_15555	COG2205	protein histidine kinase activity
EQK04_15560	COG0745	RESPONSE REGULATOR receiver
EQK04_15565	COG1120	ATPase activity
EQK04_15570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQK04_15575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQK04_15580	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQK04_15585	COG0531	amino acid
EQK04_15605	COG1988	membrane-bound metal-dependent
EQK04_15610	COG1368	sulfuric ester hydrolase activity
EQK04_15615	COG0725	ABC transporter, periplasmic molybdate-binding protein
EQK04_15620	COG4149	molybdate abc transporter
EQK04_15625	COG0656	L-ascorbic acid biosynthetic process
EQK04_15630	COG1940	carbohydrate kinase activity
EQK04_15635	COG0025	NhaP-type Na H and K H
EQK04_15640	COG2860	membrane
EQK04_15645	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EQK04_15650	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EQK04_15655	COG2217	Heavy metal translocating P-type atpase
EQK04_15660	COG1121	(ABC) transporter
EQK04_15665	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EQK04_15670	COG0803	Belongs to the bacterial solute-binding protein 9 family
EQK04_15680	COG3226	Transcriptional regulator
EQK04_15685	COG0784	Response regulator, receiver
EQK04_15690	COG4191	Histidine kinase
EQK04_15695	COG1027	Aspartate ammonia-lyase
EQK04_15710	COG2217	Heavy metal translocating P-type atpase
EQK04_15715	COG2608	mercury ion transmembrane transporter activity
EQK04_15720	COG1937	Protein conserved in bacteria
EQK04_15755	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EQK04_15760	COG0557	exoribonuclease II activity
EQK04_15765	COG1647	Serine aminopeptidase, S33
EQK04_15770	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EQK04_15775	COG2002	toxin-antitoxin pair type II binding
EQK04_15780	COG1476	TRANSCRIPTIONal
EQK04_15785	COG1396	sequence-specific DNA binding
EQK04_15790	COG1396	sequence-specific DNA binding
EQK04_15795	COG1733	regulation of RNA biosynthetic process
EQK04_15800	COG1174	glycine betaine transport
EQK04_15805	COG1732	Glycine betaine
EQK04_15810	COG1174	glycine betaine transport
EQK04_15815	COG0517	IMP dehydrogenase activity
EQK04_15815	COG1125	glycine betaine transport
EQK04_15820	COG1510	regulation of RNA biosynthetic process
EQK04_15825	COG2095	MarC family integral membrane protein
EQK04_15835	COG0456	acetyltransferase
EQK04_15855	COG1131	(ABC) transporter
EQK04_15865	COG0148	phosphopyruvate hydratase activity
EQK04_15870	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EQK04_15875	COG0149	triose-phosphate isomerase activity
EQK04_15880	COG0126	phosphoglycerate kinase activity
EQK04_15885	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EQK04_15890	COG2390	Transcriptional regulator
EQK04_15895	COG0833	amino acid
EQK04_15900	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EQK04_15905	COG3829	transcription factor binding
EQK04_15910	COG2186	Transcriptional regulator
EQK04_15915	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EQK04_15925	COG0534	Mate efflux family protein
EQK04_15930	COG4608	Belongs to the ABC transporter superfamily
EQK04_15935	COG0444	Belongs to the ABC transporter superfamily
EQK04_15940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EQK04_15945	COG0601	transmembrane transport
EQK04_15950	COG0747	negative chemotaxis
EQK04_15955	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EQK04_15960	COG0110	maltose O-acetyltransferase activity
EQK04_15965	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EQK04_15970	COG2244	polysaccharide biosynthetic process
EQK04_15975	COG5039	Polysaccharide pyruvyl transferase
EQK04_15980	COG1216	Glycosyl transferase, family 2
EQK04_15990	COG0438	transferase activity, transferring glycosyl groups
EQK04_15995	COG1215	transferase activity, transferring glycosyl groups
EQK04_16000	COG0438	transferase activity, transferring glycosyl groups
EQK04_16005	COG1086	Polysaccharide biosynthesis protein
EQK04_16010	COG0489	protein tyrosine kinase activity
EQK04_16015	COG3944	biosynthesis protein
EQK04_16020	COG1396	sequence-specific DNA binding
EQK04_16030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQK04_16035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQK04_16040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQK04_16045	COG0726	polysaccharide deacetylase
EQK04_16055	COG4608	Belongs to the ABC transporter superfamily
EQK04_16070	COG0601	transmembrane transport
EQK04_16075	COG0747	negative chemotaxis
EQK04_16085	COG1819	glycosyl
EQK04_16105	COG0740	serine-type endopeptidase activity
EQK04_16110	COG1611	Belongs to the LOG family
EQK04_16115	COG1694	Mazg nucleotide pyrophosphohydrolase
EQK04_16120	COG0659	secondary active sulfate transmembrane transporter activity
EQK04_16125	COG0288	reversible hydration of carbon dioxide
EQK04_16130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EQK04_16145	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EQK04_16150	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQK04_16155	COG1481	regulation of sporulation
EQK04_16160	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EQK04_16165	COG1660	Displays ATPase and GTPase activities
EQK04_16170	COG1051	belongs to the nudix hydrolase family
EQK04_16175	COG0492	ferredoxin-NADP+ reductase activity
EQK04_16180	COG3883	PFAM NLP P60 protein
EQK04_16180	COG0791	NLP P60 protein
EQK04_16185	COG0457	Tetratricopeptide repeat
EQK04_16190	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EQK04_16190	COG0140	phosphoribosyl-ATP diphosphatase activity
EQK04_16195	COG0107	imidazoleglycerol-phosphate synthase activity
EQK04_16200	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EQK04_16205	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EQK04_16210	COG0131	Imidazoleglycerol-phosphate dehydratase
EQK04_16215	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EQK04_16220	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EQK04_16225	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EQK04_16230	COG4990	cell redox homeostasis
EQK04_16240	COG2910	NAD(P)H-binding
EQK04_16245	COG1959	2 iron, 2 sulfur cluster binding
EQK04_16250	COG0110	maltose O-acetyltransferase activity
EQK04_16255	COG0546	phosphoglycolate phosphatase activity
EQK04_16260	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EQK04_16270	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EQK04_16275	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EQK04_16280	COG0363	glucosamine-6-phosphate deaminase activity
EQK04_16285	COG2188	Transcriptional regulator
EQK04_16290	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EQK04_16295	COG1950	PFAM Membrane protein of
EQK04_16300	COG1983	PspC domain protein
EQK04_16305	COG3595	metallopeptidase activity
EQK04_16320	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EQK04_16330	COG4897	Protein conserved in bacteria
EQK04_16335	COG0574	Belongs to the PEP-utilizing enzyme family
EQK04_16335	COG3848	Pyruvate phosphate dikinase
EQK04_16340	COG1309	transcriptional regulator
EQK04_16345	COG2814	Major facilitator Superfamily
EQK04_16355	COG0745	RESPONSE REGULATOR receiver
EQK04_16360	COG5002	protein histidine kinase activity
EQK04_16365	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EQK04_16370	COG0463	Glycosyl transferase, family 2
EQK04_16375	COG1113	amino acid transport
EQK04_16380	COG0778	Nitroreductase
EQK04_16385	COG1733	regulation of RNA biosynthetic process
EQK04_16390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EQK04_16400	COG0793	Belongs to the peptidase S41A family
EQK04_16400	COG3409	Peptidoglycan-binding domain 1 protein
EQK04_16405	COG0730	response to heat
EQK04_16410	COG0791	NLP P60 protein
EQK04_16410	COG3883	PFAM NLP P60 protein
EQK04_16415	COG2177	Part of the ABC transporter FtsEX involved in
EQK04_16420	COG2884	Cell division ATP-binding protein ftsE
EQK04_16425	COG2010	Cytochrome c
EQK04_16430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQK04_16450	COG0653	protein targeting
EQK04_16455	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EQK04_16460	COG0840	transmembrane signaling receptor activity
EQK04_16475	COG1516	flagellar protein fliS
EQK04_16480	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EQK04_16485	COG1334	flagellar protein FlaG
EQK04_16490	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EQK04_16495	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
EQK04_16505	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EQK04_16510	COG4786	Flagellar basal body rod
EQK04_16510	COG1256	bacterial-type flagellum assembly
EQK04_16515	COG3418	PFAM FlgN family protein
EQK04_16530	COG1040	competence protein
EQK04_16540	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EQK04_16545	COG1307	EDD domain protein, DegV family
EQK04_16550	COG2197	response regulator
EQK04_16555	COG4585	Histidine kinase
EQK04_16560	COG1739	Uncharacterized protein family UPF0029
EQK04_16565	COG1316	TRANSCRIPTIONal
EQK04_16570	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EQK04_16575	COG0438	transferase activity, transferring glycosyl groups
EQK04_16580	COG1215	transferase activity, transferring glycosyl groups
EQK04_16585	COG3206	protein involved in exopolysaccharide biosynthesis
EQK04_16590	COG3307	-O-antigen
EQK04_16595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EQK04_16600	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EQK04_16605	COG0297	glycogen (starch) synthase activity
EQK04_16605	COG0438	transferase activity, transferring glycosyl groups
EQK04_16610	COG2244	polysaccharide biosynthetic process
EQK04_16625	COG2247	cell wall binding repeat
EQK04_16625	COG0860	N-Acetylmuramoyl-L-alanine amidase
EQK04_16630	COG0860	N-Acetylmuramoyl-L-alanine amidase
EQK04_16630	COG2247	cell wall binding repeat
EQK04_16635	COG2385	sporulation resulting in formation of a cellular spore
EQK04_16635	COG2247	cell wall binding repeat
EQK04_16645	COG1316	TRANSCRIPTIONal
EQK04_16650	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EQK04_16655	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EQK04_16660	COG1134	teichoic acid transport
EQK04_16665	COG1682	transport, permease protein
EQK04_16670	COG0463	Glycosyl transferase, family 2
EQK04_16670	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EQK04_16675	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EQK04_16685	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EQK04_16690	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EQK04_16695	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EQK04_16700	COG4193	domain, Protein
EQK04_16705	COG1482	cell wall glycoprotein biosynthetic process
EQK04_16715	COG1175	transmembrane transport
EQK04_16720	COG1653	transport
EQK04_16725	COG2197	response regulator
EQK04_16730	COG2972	Histidine kinase
EQK04_16740	COG0454	-acetyltransferase
EQK04_16745	COG0800	Aldolase
EQK04_16750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EQK04_16755	COG1609	Transcriptional regulator
EQK04_16760	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
EQK04_16765	COG1028	Short-chain dehydrogenase reductase Sdr
EQK04_16770	COG0697	spore germination
EQK04_16775	COG0814	amino acid
EQK04_16790	COG2814	Major facilitator Superfamily
EQK04_16795	COG1316	TRANSCRIPTIONal
EQK04_16800	COG0561	phosphatase activity
EQK04_16805	COG0791	NLP P60 protein
EQK04_16810	COG2843	Capsule synthesis protein
EQK04_16820	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EQK04_16825	COG0697	spore germination
EQK04_16840	COG1609	Transcriptional regulator
EQK04_16845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EQK04_16850	COG1869	D-ribose catabolic process
EQK04_16855	COG1129	ABC transporter
EQK04_16860	COG1172	Belongs to the binding-protein-dependent transport system permease family
EQK04_16865	COG1879	ABC-type sugar transport system periplasmic component
EQK04_16870	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EQK04_16875	COG0583	DNA-binding transcription factor activity
EQK04_16880	COG0028	Belongs to the TPP enzyme family
EQK04_16885	COG3527	Alpha-acetolactate decarboxylase
EQK04_16890	COG1522	sequence-specific DNA binding
EQK04_16895	COG2059	Chromate
EQK04_16900	COG2059	Chromate
EQK04_16905	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EQK04_16910	COG4715	Zinc finger, swim domain protein
EQK04_16915	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EQK04_16920	COG1366	Belongs to the anti-sigma-factor antagonist family
EQK04_16920	COG2202	Pas domain
EQK04_16925	COG0561	phosphatase activity
EQK04_16940	COG1970	mechanosensitive ion channel activity
EQK04_16945	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EQK04_16950	COG0457	Tetratricopeptide repeat
EQK04_16955	COG4786	Flagellar basal body rod
EQK04_16960	COG4786	Flagellar basal body rod
EQK04_16965	COG1077	Cell shape determining protein MreB Mrl
EQK04_16970	COG1609	Transcriptional regulator
EQK04_16975	COG1846	Transcriptional regulator
EQK04_16980	COG2814	Major facilitator Superfamily
EQK04_16985	COG0671	phosphoesterase, PA-phosphatase related
EQK04_16990	COG0477	Major facilitator Superfamily
EQK04_16995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQK04_17000	COG0765	amino acid transport
EQK04_17005	COG1126	abc transporter atp-binding protein
EQK04_17010	COG0004	ammonium transporteR
EQK04_17015	COG0347	Belongs to the P(II) protein family
EQK04_17020	COG0739	heme binding
EQK04_17025	COG1247	-acetyltransferase
EQK04_17070	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EQK04_17075	COG0523	cobalamin synthesis protein
EQK04_17080	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EQK04_17085	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EQK04_17090	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EQK04_17095	COG2223	nitrite transmembrane transporter activity
EQK04_17105	COG2304	oxidoreductase activity
EQK04_17110	COG2304	oxidoreductase activity
EQK04_17115	COG2385	sporulation resulting in formation of a cellular spore
EQK04_17120	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EQK04_17130	COG4836	Membrane
EQK04_17140	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EQK04_17145	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EQK04_17150	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EQK04_17155	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EQK04_17160	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EQK04_17165	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EQK04_17170	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EQK04_17175	COG0356	it plays a direct role in the translocation of protons across the membrane
EQK04_17185	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EQK04_17190	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EQK04_17195	COG4475	Protein of unknown function (DUF436)
EQK04_17200	COG0698	ribose 5-phosphate isomerase
EQK04_17205	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EQK04_17210	COG1971	Probably functions as a manganese efflux pump
EQK04_17215	COG0009	L-threonylcarbamoyladenylate synthase
EQK04_17220	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EQK04_17235	COG2890	protein-(glutamine-N5) methyltransferase activity
EQK04_17240	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EQK04_17245	COG0789	Transcriptional regulator
EQK04_17250	COG0679	Auxin Efflux Carrier
EQK04_17255	COG0281	malic enzyme
EQK04_17260	COG1435	thymidine kinase activity
EQK04_17265	COG0254	rRNA binding
EQK04_17270	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EQK04_17275	COG1494	fructose-1,6-bisphosphatase
EQK04_17280	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EQK04_17285	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EQK04_17290	COG0191	fructose-bisphosphate aldolase activity
EQK04_17295	COG2204	response regulator
EQK04_17300	COG4821	SIS domain
EQK04_17305	COG0504	CTP synthase activity
EQK04_17310	COG3343	RNA polymerase activity
EQK04_17325	COG1960	acyl-CoA dehydrogenase activity
EQK04_17330	COG1960	acyl-CoA dehydrogenase activity
EQK04_17335	COG1250	3-hydroxyacyl-CoA dehydrogenase
EQK04_17340	COG0183	Belongs to the thiolase family
EQK04_17345	COG2181	nitrate reductase activity
EQK04_17345	COG0247	lactate metabolic process
EQK04_17350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EQK04_17355	COG4294	response to UV
EQK04_17365	COG1619	proteins homologs of microcin C7 resistance protein MccF
EQK04_17375	COG1132	(ABC) transporter
EQK04_17380	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EQK04_17385	COG1619	proteins homologs of microcin C7 resistance protein MccF
EQK04_17390	COG0018	arginyl-trna synthetase
EQK04_17395	COG4506	Protein conserved in bacteria
EQK04_17405	COG0010	Belongs to the arginase family
EQK04_17410	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EQK04_17415	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EQK04_17425	COG1994	Peptidase M50
EQK04_17430	COG1942	4-Oxalocrotonate Tautomerase
EQK04_17440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQK04_17445	COG0583	DNA-binding transcription factor activity
EQK04_17450	COG0431	NADPH-dependent FMN reductase
EQK04_17455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQK04_17460	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EQK04_17465	COG0454	-acetyltransferase
EQK04_17470	COG0765	amino acid transport
EQK04_17480	COG0765	amino acid transport
EQK04_17485	COG1126	abc transporter atp-binding protein
EQK04_17490	COG3465	dGTPase activity
EQK04_17495	COG1078	dGTPase activity
EQK04_17500	COG4844	belongs to the
EQK04_17550	COG5444	nuclease activity
EQK04_17580	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EQK04_17590	COG0280	phosphate acetyltransferase
EQK04_17600	COG2814	Major facilitator Superfamily
EQK04_17605	COG1522	sequence-specific DNA binding
EQK04_17610	COG2814	Major facilitator Superfamily
EQK04_17615	COG0077	Prephenate dehydratase
EQK04_17620	COG1917	Cupin 2, conserved barrel domain protein
EQK04_17625	COG1028	Short-chain dehydrogenase reductase Sdr
EQK04_17630	COG0151	Belongs to the GarS family
EQK04_17635	COG0436	Aminotransferase
EQK04_17640	COG1028	Short-chain dehydrogenase reductase Sdr
EQK04_17645	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
EQK04_17650	COG1091	dTDP-4-dehydrorhamnose reductase activity
EQK04_17655	COG1088	dTDP-glucose 4,6-dehydratase activity
EQK04_17660	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EQK04_17665	COG3980	spore coat polysaccharide biosynthesis protein
EQK04_17670	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
EQK04_17675	COG2089	acid synthase
EQK04_17680	COG0456	acetyltransferase
EQK04_17685	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EQK04_17690	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EQK04_17695	COG0463	Glycosyl transferase, family 2
EQK04_17715	COG2363	Small membrane protein
EQK04_17720	COG2233	PERMEase
EQK04_17730	COG1012	belongs to the aldehyde dehydrogenase family
EQK04_17735	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EQK04_17740	COG1216	Glycosyl transferase, family 2
EQK04_17750	COG0351	phosphomethylpyrimidine kinase
EQK04_17765	COG1621	beta-fructofuranosidase activity
EQK04_17770	COG1263	PTS System
EQK04_17770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQK04_17775	COG3711	transcriptional antiterminator
EQK04_17785	COG1404	Belongs to the peptidase S8 family
EQK04_17795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQK04_17800	COG0778	Nitroreductase
EQK04_17805	COG0772	Belongs to the SEDS family
EQK04_17815	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EQK04_17820	COG1845	cytochrome c oxidase, subunit III
EQK04_17825	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EQK04_17830	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EQK04_17840	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EQK04_17845	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EQK04_17850	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EQK04_17865	COG2246	polysaccharide biosynthetic process
EQK04_17895	COG0457	Tetratricopeptide repeat
EQK04_17910	COG3162	membrane
EQK04_17915	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EQK04_17935	COG0352	thiamine-phosphate diphosphorylase activity
EQK04_17940	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EQK04_17945	COG0583	DNA-binding transcription factor activity
EQK04_17950	COG1380	Effector of murein hydrolase LrgA
EQK04_17955	COG1346	cytolysis
EQK04_17960	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EQK04_17965	COG0346	lactoylglutathione lyase activity
EQK04_17975	COG0765	amino acid transport
EQK04_17980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQK04_17985	COG0457	Tetratricopeptide repeat
EQK04_17990	COG2357	RelA SpoT domain protein
EQK04_17995	COG1172	Belongs to the binding-protein-dependent transport system permease family
EQK04_18000	COG1129	ABC transporter
EQK04_18010	COG3420	alginic acid biosynthetic process
EQK04_18015	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EQK04_18030	COG1486	melibiose metabolic process
EQK04_18035	COG1447	Phosphotransferase system cellobiose-specific component IIA
EQK04_18040	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQK04_18045	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQK04_18050	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQK04_18050	COG3711	transcriptional antiterminator
EQK04_18065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EQK04_18080	COG1595	DNA-templated transcription, initiation
EQK04_18090	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EQK04_18095	COG4988	ABC transporter
EQK04_18100	COG1294	oxidase, subunit
EQK04_18105	COG1271	oxidase subunit
EQK04_18110	COG1120	ATPase activity
EQK04_18115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQK04_18120	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EQK04_18125	COG4509	Sortase family
EQK04_18150	COG5386	Cell surface protein
EQK04_18155	COG5386	Cell surface protein
EQK04_18160	COG1733	regulation of RNA biosynthetic process
EQK04_18165	COG2514	catechol 2,3-dioxygenase activity
EQK04_18170	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EQK04_18170	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EQK04_18175	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EQK04_18175	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EQK04_18185	COG0726	polysaccharide deacetylase
EQK04_18190	COG1447	Phosphotransferase system cellobiose-specific component IIA
EQK04_18195	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQK04_18200	COG2723	6-phospho-beta-galactosidase activity
EQK04_18210	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQK04_18215	COG3711	transcriptional antiterminator
EQK04_18215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQK04_18240	COG1757	Na H antiporter
EQK04_18245	COG1027	Aspartate ammonia-lyase
EQK04_18250	COG0252	asparaginase activity
EQK04_18255	COG1396	sequence-specific DNA binding
EQK04_18280	COG4842	Belongs to the WXG100 family
EQK04_18285	COG2195	Cleaves the N-terminal amino acid of tripeptides
EQK04_18300	COG1737	Transcriptional regulator
EQK04_18305	COG2084	Dehydrogenase
EQK04_18315	COG2610	gluconate transmembrane transporter activity
EQK04_18320	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EQK04_18345	COG2723	6-phospho-beta-galactosidase activity
EQK04_18350	COG1263	PTS System
EQK04_18350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQK04_18350	COG2190	(PTS) system
EQK04_18355	COG3711	transcriptional antiterminator
EQK04_18360	COG3878	Protein conserved in bacteria
EQK04_18370	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EQK04_18375	COG1122	ATPase activity
EQK04_18380	COG4721	ABC-type cobalt transport system, permease component
EQK04_18385	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EQK04_18420	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EQK04_18425	COG0778	Nitroreductase
EQK04_18430	COG1846	Transcriptional regulator
EQK04_18435	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EQK04_18440	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EQK04_18445	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EQK04_18450	COG2390	Transcriptional regulator
EQK04_18460	COG2755	lipolytic protein G-D-S-L family
EQK04_18460	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EQK04_18465	COG0477	Major facilitator Superfamily
EQK04_18470	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EQK04_18475	COG2226	methyltransferase
EQK04_18485	COG0561	phosphatase activity
EQK04_18490	COG0789	Transcriptional regulator
EQK04_18495	COG0673	inositol 2-dehydrogenase activity
EQK04_18500	COG0840	transmembrane signaling receptor activity
EQK04_18505	COG1113	amino acid transport
EQK04_18510	COG4335	DNA alkylation repair
EQK04_18520	COG1070	Carbohydrate kinase
EQK04_18525	COG1737	Transcriptional regulator
EQK04_18565	COG0583	DNA-binding transcription factor activity
EQK04_18570	COG1609	Transcriptional regulator
EQK04_18575	COG2182	Extracellular solute-binding protein
EQK04_18580	COG1175	transmembrane transport
EQK04_18585	COG3833	ABC-type maltose transport systems, permease component
EQK04_18595	COG1874	Beta-galactosidase
EQK04_18600	COG2851	Citrate transporter
EQK04_18610	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EQK04_18615	COG1131	(ABC) transporter
EQK04_18620	COG2824	Alkylphosphonate utilization operon protein PhnA
EQK04_18625	COG1929	Belongs to the glycerate kinase type-1 family
EQK04_18630	COG2610	gluconate transmembrane transporter activity
EQK04_18635	COG3835	regulator
EQK04_18640	COG1309	transcriptional regulator
EQK04_18655	COG1136	(ABC) transporter
EQK04_18665	COG0457	Tetratricopeptide repeat
EQK04_18670	COG3711	transcriptional antiterminator
EQK04_18675	COG2723	6-phospho-beta-galactosidase activity
EQK04_18680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQK04_18680	COG2190	(PTS) system
EQK04_18680	COG1263	PTS System
EQK04_18705	COG0494	nUDIX hydrolase
EQK04_18720	COG1113	amino acid transport
EQK04_18735	COG2814	Major facilitator Superfamily
EQK04_18740	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EQK04_18745	COG2814	Major facilitator Superfamily
EQK04_18770	COG5444	nuclease activity
EQK04_18785	COG2723	6-phospho-beta-galactosidase activity
EQK04_18795	COG2188	Transcriptional regulator
EQK04_18810	COG0384	phenazine biosynthesis protein PhzF
EQK04_18815	COG0583	DNA-binding transcription factor activity
EQK04_18835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EQK04_18840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EQK04_18865	COG0210	DNA helicase
EQK04_18870	COG0210	DNA helicase
EQK04_18880	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EQK04_18890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EQK04_18900	COG4720	Psort location CytoplasmicMembrane, score
EQK04_18920	COG0456	acetyltransferase
EQK04_18925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EQK04_18930	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EQK04_18935	COG4853	Protein conserved in bacteria
EQK04_18940	COG4863	YycH protein
EQK04_18945	COG5002	protein histidine kinase activity
EQK04_18950	COG0745	RESPONSE REGULATOR receiver
EQK04_18975	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EQK04_18985	COG2311	Membrane
EQK04_18990	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EQK04_18995	COG1309	transcriptional regulator
EQK04_19000	COG2124	cytochrome p450
EQK04_19005	COG0346	lactoylglutathione lyase activity
EQK04_19010	COG0305	Participates in initiation and elongation during chromosome replication
EQK04_19025	COG2819	hydrolase of the alpha beta superfamily
EQK04_19030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQK04_19030	COG2207	Transcriptional regulator
EQK04_19035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQK04_19040	COG2819	hydrolase of the alpha beta superfamily
EQK04_19045	COG3093	addiction module antidote protein HigA
EQK04_19050	COG2807	transmembrane transport
EQK04_19055	COG0359	binds to the 23S rRNA
EQK04_19060	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EQK04_19065	COG4241	membrane
EQK04_19070	COG1227	inorganic diphosphatase activity
EQK04_19080	COG1595	DNA-templated transcription, initiation
EQK04_19090	COG0753	catalase activity
EQK04_19095	COG0655	NAD(P)H dehydrogenase (quinone) activity
EQK04_19100	COG0400	carboxylic ester hydrolase activity
EQK04_19105	COG0346	lactoylglutathione lyase activity
EQK04_19110	COG1174	glycine betaine transport
EQK04_19115	COG1125	glycine betaine transport
EQK04_19115	COG0517	IMP dehydrogenase activity
EQK04_19120	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EQK04_19125	COG0629	single-stranded DNA binding
EQK04_19130	COG0360	Binds together with S18 to 16S ribosomal RNA
EQK04_19135	COG0012	GTP binding
EQK04_19140	COG4481	Protein conserved in bacteria
EQK04_19155	COG3949	Membrane
EQK04_19165	COG1475	DNA binding
EQK04_19170	COG1192	Involved in chromosome partitioning
EQK04_19180	COG1475	DNA binding
EQK04_19185	COG0357	Ribosomal RNA small subunit methyltransferase G
EQK04_19190	COG0445	tRNA wobble uridine modification
EQK04_19195	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EQK04_19200	COG1847	R3H domain protein
EQK04_19205	COG0706	membrane insertase activity
EQK04_19210	COG0594	ribonuclease P activity
EQK04_19215	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EQK04_19220	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EQK04_19225	COG0592	DNA-directed DNA polymerase activity
EQK04_19230	COG2501	S4 domain
EQK04_19235	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EQK04_19245	COG0187	DNA topoisomerase II activity
EQK04_19250	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EQK04_19285	COG0517	IMP dehydrogenase activity
EQK04_19285	COG0516	GMP reductase activity
EQK04_19290	COG1686	Belongs to the peptidase S11 family
EQK04_19295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQK04_19300	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EQK04_19305	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EQK04_19310	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EQK04_19315	COG0840	transmembrane signaling receptor activity
EQK04_19325	COG1428	Deoxynucleoside kinase
EQK04_19330	COG1428	Deoxynucleoside kinase
EQK04_19335	COG3858	chitin binding
EQK04_19335	COG1388	LysM domain
EQK04_19340	COG1335	isochorismatase
EQK04_19345	COG0590	tRNA wobble adenosine to inosine editing
EQK04_19355	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EQK04_19360	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EQK04_19365	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO