locus-tag	class	description
M1M81_00010	COG0592	DNA-directed DNA polymerase activity
M1M81_00015	COG2501	S4 domain
M1M81_00030	COG0187	DNA topoisomerase II activity
M1M81_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
M1M81_00070	COG0516	GMP reductase activity
M1M81_00070	COG0517	IMP dehydrogenase activity
M1M81_00075	COG1686	Belongs to the peptidase S11 family
M1M81_00095	COG1929	Belongs to the glycerate kinase type-1 family
M1M81_00105	COG1428	Deoxynucleoside kinase
M1M81_00110	COG1428	Deoxynucleoside kinase
M1M81_00115	COG1388	LysM domain
M1M81_00115	COG3858	chitin binding
M1M81_00120	COG1335	isochorismatase
M1M81_00125	COG0590	tRNA wobble adenosine to inosine editing
M1M81_00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
M1M81_00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
M1M81_00145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
M1M81_00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
M1M81_00195	COG3853	Toxic anion resistance protein (TelA)
M1M81_00200	COG1982	Orn Lys Arg decarboxylase major
M1M81_00210	COG3870	Protein conserved in bacteria
M1M81_00215	COG1728	Protein conserved in bacteria
M1M81_00220	COG0470	DNA polymerase III
M1M81_00225	COG1774	PSP1 C-terminal conserved region
M1M81_00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
M1M81_00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
M1M81_00250	COG2002	toxin-antitoxin pair type II binding
M1M81_00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1M81_00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1M81_00260	COG0084	hydrolase, TatD family'
M1M81_00265	COG3584	3D domain protein
M1M81_00265	COG3583	domain protein
M1M81_00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
M1M81_00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
M1M81_00285	COG4466	Protein conserved in bacteria
M1M81_00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
M1M81_00305	COG0251	oxidation-reduction process
M1M81_00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
M1M81_00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
M1M81_00345	COG2002	toxin-antitoxin pair type II binding
M1M81_00350	COG2244	polysaccharide biosynthetic process
M1M81_00355	COG3956	TIGRFAM MazG family protein
M1M81_00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
M1M81_00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
M1M81_00380	COG1098	S1 RNA binding domain
M1M81_00395	COG2208	phosphoserine phosphatase activity
M1M81_00400	COG2304	oxidoreductase activity
M1M81_00405	COG0515	serine threonine protein kinase
M1M81_00410	COG0037	tRNA processing
M1M81_00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
M1M81_00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M1M81_00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M1M81_00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M1M81_00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
M1M81_00450	COG0512	Glutamine amidotransferase of anthranilate synthase
M1M81_00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M1M81_00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
M1M81_00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
M1M81_00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
M1M81_00475	COG1396	sequence-specific DNA binding
M1M81_00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M1M81_00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
M1M81_00565	COG4463	regulation of RNA biosynthetic process
M1M81_00570	COG3880	PFAM UvrB UvrC protein
M1M81_00580	COG0542	response to heat
M1M81_00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
M1M81_00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
M1M81_00595	COG4956	integral membrane protein (PIN domain superfamily)
M1M81_00615	COG1045	serine acetyltransferase
M1M81_00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
M1M81_00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M1M81_00635	COG3688	RNA-binding protein containing a PIN domain
M1M81_00640	COG1595	DNA-templated transcription, initiation
M1M81_00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
M1M81_00655	COG0250	Participates in transcription elongation, termination and antitermination
M1M81_00680	COG2813	Specifically methylates the guanine in position
M1M81_00695	COG1358	cellular component organization or biogenesis
M1M81_00720	COG0596	Alpha beta hydrolase
M1M81_00815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
M1M81_00830	COG0201	protein transport
M1M81_00840	COG0024	Methionine aminopeptidase
M1M81_00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
M1M81_00880	COG1122	ATPase activity
M1M81_00885	COG1122	ATPase activity
M1M81_00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
M1M81_00910	COG2226	methyltransferase
M1M81_00915	COG2318	DinB family
M1M81_00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
M1M81_00930	COG0489	protein tyrosine kinase activity
M1M81_00940	COG2194	sulfuric ester hydrolase activity
M1M81_00945	COG0726	polysaccharide deacetylase
M1M81_01005	COG0738	Major facilitator superfamily
M1M81_01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M1M81_01020	COG1063	alcohol dehydrogenase
M1M81_01025	COG0659	secondary active sulfate transmembrane transporter activity
M1M81_01030	COG0385	Bile acid
M1M81_01035	COG2819	hydrolase of the alpha beta superfamily
M1M81_01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1M81_01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1M81_01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M1M81_01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M1M81_01055	COG2207	Transcriptional regulator
M1M81_01060	COG3876	Protein conserved in bacteria
M1M81_01065	COG1472	Belongs to the glycosyl hydrolase 3 family
M1M81_01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1M81_01075	COG1263	PTS System
M1M81_01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M1M81_01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1M81_01090	COG1683	Conserved Protein
M1M81_01120	COG1595	DNA-templated transcription, initiation
M1M81_01125	COG5662	AntiSigma factor
M1M81_01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
M1M81_01135	COG4856	YbbR-like protein
M1M81_01170	COG5002	protein histidine kinase activity
M1M81_01175	COG1136	(ABC) transporter
M1M81_01180	COG0577	efflux transmembrane transporter activity
M1M81_01185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M1M81_01200	COG1346	cytolysis
M1M81_01205	COG1380	Effector of murein hydrolase LrgA
M1M81_01210	COG1846	Transcriptional regulator
M1M81_01215	COG1113	amino acid transport
M1M81_01220	COG1011	Hydrolase
M1M81_01225	COG4585	Histidine kinase
M1M81_01230	COG2197	response regulator
M1M81_01235	COG1131	(ABC) transporter
M1M81_01275	COG0531	amino acid
M1M81_01280	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
M1M81_01295	COG0584	glycerophosphoryl diester phosphodiesterase
M1M81_01300	COG2271	Major facilitator Superfamily
M1M81_01310	COG2368	4-hydroxyphenylacetate
M1M81_01320	COG3409	Peptidoglycan-binding domain 1 protein
M1M81_01335	COG1397	ADP-ribosylglycohydrolase
M1M81_01340	COG5444	nuclease activity
M1M81_01350	COG0371	Dehydrogenase
M1M81_01360	COG1183	phosphatidylcholine synthase activity
M1M81_01365	COG0586	Pfam SNARE associated Golgi protein
M1M81_01370	COG0688	phosphatidylethanolamine metabolic process
M1M81_01385	COG1301	dicarboxylic acid transport
M1M81_01390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M1M81_01395	COG0833	amino acid
M1M81_01400	COG2040	homocysteine
M1M81_01405	COG1115	amino acid carrier protein
M1M81_01410	COG2066	Belongs to the glutaminase family
M1M81_01415	COG4191	Histidine kinase
M1M81_01420	COG0784	Response regulator, receiver
M1M81_01440	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
M1M81_01445	COG0778	Nitroreductase
M1M81_01450	COG0346	lactoylglutathione lyase activity
M1M81_01455	COG2259	Doxx family
M1M81_01460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M1M81_01475	COG3773	Cell wall hydrolase
M1M81_01480	COG3540	Alkaline phosphatase
M1M81_01485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
M1M81_01490	COG0805	protein transport
M1M81_01500	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
M1M81_01505	COG0477	Major facilitator Superfamily
M1M81_01510	COG1309	transcriptional regulator
M1M81_01515	COG0252	asparaginase activity
M1M81_01520	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
M1M81_01525	COG3012	SEC-C Motif Domain Protein
M1M81_01525	COG1405	negative regulation of cell septum assembly
M1M81_01540	COG1595	DNA-templated transcription, initiation
M1M81_01545	COG1595	DNA-templated transcription, initiation
M1M81_01550	COG1876	peptidase activity
M1M81_01555	COG0457	Tetratricopeptide repeat
M1M81_01560	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_01565	COG0366	Alpha amylase catalytic
M1M81_01570	COG0803	Belongs to the bacterial solute-binding protein 9 family
M1M81_01575	COG1121	(ABC) transporter
M1M81_01580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M1M81_01585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1M81_01590	COG2310	stress, protein
M1M81_01595	COG2310	stress, protein
M1M81_01600	COG2310	stress, protein
M1M81_01605	COG0861	Integral membrane protein TerC family
M1M81_01615	COG3853	Toxic anion resistance protein (TelA)
M1M81_01620	COG0477	Major facilitator Superfamily
M1M81_01625	COG4175	Glycine betaine
M1M81_01625	COG0517	IMP dehydrogenase activity
M1M81_01630	COG4176	ABC-type proline glycine betaine transport system permease component
M1M81_01635	COG2113	Glycine betaine
M1M81_01640	COG1473	amidohydrolase
M1M81_01645	COG1288	antiporter activity
M1M81_01665	COG2814	Major facilitator Superfamily
M1M81_01670	COG1846	Transcriptional regulator
M1M81_01675	COG1280	lysine exporter protein (LysE YggA)
M1M81_01680	COG3403	YqcI/YcgG family
M1M81_01685	COG1113	amino acid transport
M1M81_01690	COG3665	Urea carboxylase-associated protein
M1M81_01705	COG1660	Displays ATPase and GTPase activities
M1M81_01710	COG1082	Xylose isomerase domain protein TIM barrel
M1M81_01715	COG2271	Major facilitator Superfamily
M1M81_01720	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
M1M81_01725	COG3458	cephalosporin-C deacetylase activity
M1M81_01730	COG3541	Predicted nucleotidyltransferase
M1M81_01735	COG0506	proline dehydrogenase activity
M1M81_01740	COG1012	belongs to the aldehyde dehydrogenase family
M1M81_01745	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M1M81_01750	COG2508	Transcriptional regulator
M1M81_01760	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
M1M81_01760	COG1587	Uroporphyrinogen-III synthase
M1M81_01765	COG2146	nitrite reductase [NAD(P)H] activity
M1M81_01770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1M81_01775	COG0243	molybdopterin cofactor binding
M1M81_01780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1M81_01785	COG2223	nitrite transmembrane transporter activity
M1M81_01790	COG0523	cobalamin synthesis protein
M1M81_01795	COG1063	alcohol dehydrogenase
M1M81_01800	COG1714	RDD family
M1M81_01820	COG3209	COG3209 Rhs family protein
M1M81_01825	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
M1M81_01830	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
M1M81_01835	COG1733	regulation of RNA biosynthetic process
M1M81_01840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1M81_01860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1M81_01865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1M81_01870	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
M1M81_01885	COG2364	Membrane
M1M81_01890	COG1126	abc transporter atp-binding protein
M1M81_01895	COG0765	amino acid transport
M1M81_01905	COG0583	DNA-binding transcription factor activity
M1M81_01910	COG0163	prenyltransferase activity
M1M81_01915	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
M1M81_01930	COG3104	oligopeptide transport
M1M81_01935	COG5434	Belongs to the glycosyl hydrolase 28 family
M1M81_01945	COG0697	spore germination
M1M81_01955	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
M1M81_01960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1M81_01965	COG0456	acetyltransferase
M1M81_01970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1M81_01975	COG0765	amino acid transport
M1M81_01980	COG1126	abc transporter atp-binding protein
M1M81_01985	COG1473	amidohydrolase
M1M81_01990	COG2079	MmgE PrpD family protein
M1M81_01995	COG1136	(ABC) transporter
M1M81_02000	COG0577	efflux transmembrane transporter activity
M1M81_02005	COG0745	RESPONSE REGULATOR receiver
M1M81_02010	COG5002	protein histidine kinase activity
M1M81_02010	COG3850	Histidine kinase
M1M81_02015	COG0457	Tetratricopeptide repeat
M1M81_02030	COG0527	aspartate kinase activity
M1M81_02035	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1M81_02040	COG4605	iron ion homeostasis
M1M81_02045	COG4604	ABC transporter, ATP-binding protein
M1M81_02050	COG4607	ABC-type enterochelin transport system periplasmic component
M1M81_02055	COG2814	Major facilitator Superfamily
M1M81_02060	COG1309	transcriptional regulator
M1M81_02065	COG0778	Nitroreductase
M1M81_02070	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
M1M81_02075	COG0640	Transcriptional regulator
M1M81_02080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1M81_02085	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M1M81_02090	COG1012	belongs to the aldehyde dehydrogenase family
M1M81_02095	COG4975	Glucose uptake
M1M81_02100	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_02105	COG4549	nuclear export factor GLE1
M1M81_02110	COG1276	copper resistance
M1M81_02110	COG2372	response to copper ion
M1M81_02115	COG1349	DNA-binding transcription factor activity
M1M81_02125	COG2213	PTS system mannitol-specific
M1M81_02130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
M1M81_02140	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
M1M81_02150	COG0561	phosphatase activity
M1M81_02160	COG1914	H( )-stimulated, divalent metal cation uptake system
M1M81_02170	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
M1M81_02175	COG1984	allophanate hydrolase subunit 2
M1M81_02180	COG1414	Transcriptional regulator
M1M81_02185	COG2755	lipolytic protein G-D-S-L family
M1M81_02195	COG2329	Antibiotic biosynthesis monooxygenase
M1M81_02200	COG0768	penicillin binding
M1M81_02205	COG4989	oxidoreductase activity
M1M81_02210	COG3711	transcriptional antiterminator
M1M81_02215	COG0318	PFAM AMP-dependent synthetase and ligase
M1M81_02220	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_02225	COG1917	Cupin 2, conserved barrel domain protein
M1M81_02230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1M81_02235	COG3871	stress protein (general stress protein 26)
M1M81_02245	COG2814	Major facilitator Superfamily
M1M81_02250	COG1522	sequence-specific DNA binding
M1M81_02255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M1M81_02255	COG0551	DNA topoisomerase type I activity
M1M81_02260	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
M1M81_02265	COG3706	GGDEF domain
M1M81_02270	COG5298	Protein conserved in bacteria
M1M81_02275	COG1215	transferase activity, transferring glycosyl groups
M1M81_02285	COG0531	amino acid
M1M81_02295	COG0028	Belongs to the TPP enzyme family
M1M81_02300	COG1388	LysM domain
M1M81_02300	COG3409	Peptidoglycan-binding domain 1 protein
M1M81_02300	COG5632	N-Acetylmuramoyl-L-alanine amidase
M1M81_02320	COG0457	Tetratricopeptide repeat
M1M81_02345	COG1914	H( )-stimulated, divalent metal cation uptake system
M1M81_02365	COG2076	Multidrug Resistance protein
M1M81_02370	COG2217	Heavy metal translocating P-type atpase
M1M81_02375	COG3729	General stress protein
M1M81_02380	COG0662	Cupin 2, conserved barrel domain protein
M1M81_02385	COG2329	Antibiotic biosynthesis monooxygenase
M1M81_02390	COG3546	catalase activity
M1M81_02395	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
M1M81_02400	COG3290	protein histidine kinase activity
M1M81_02405	COG4565	transcriptional regulatory protein
M1M81_02410	COG1301	dicarboxylic acid transport
M1M81_02415	COG0628	permease
M1M81_02420	COG1131	(ABC) transporter
M1M81_02425	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
M1M81_02435	COG1960	acyl-CoA dehydrogenase activity
M1M81_02450	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
M1M81_02455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M1M81_02465	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
M1M81_02470	COG0513	Belongs to the DEAD box helicase family
M1M81_02475	COG3402	PFAM membrane-flanked domain
M1M81_02480	COG3428	Bacterial PH domain
M1M81_02485	COG0705	Rhomboid family
M1M81_02495	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
M1M81_02500	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M1M81_02505	COG0864	Transcriptional regulator
M1M81_02510	COG2337	Toxic component of a toxin-antitoxin (TA) module
M1M81_02515	COG1366	Belongs to the anti-sigma-factor antagonist family
M1M81_02520	COG1366	Belongs to the anti-sigma-factor antagonist family
M1M81_02525	COG2172	sigma factor antagonist activity
M1M81_02530	COG2208	phosphoserine phosphatase activity
M1M81_02535	COG1366	Belongs to the anti-sigma-factor antagonist family
M1M81_02545	COG1191	sigma factor activity
M1M81_02550	COG2208	phosphoserine phosphatase activity
M1M81_02555	COG2183	response to ionizing radiation
M1M81_02620	COG5444	nuclease activity
M1M81_02640	COG0477	Major facilitator Superfamily
M1M81_02655	COG2030	dehydratase
M1M81_02665	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
M1M81_02670	COG1959	2 iron, 2 sulfur cluster binding
M1M81_02675	COG2910	NAD(P)H-binding
M1M81_02680	COG3239	Fatty acid desaturase
M1M81_02685	COG1278	Cold shock
M1M81_02690	COG1329	Transcriptional regulator
M1M81_02695	COG1937	Protein conserved in bacteria
M1M81_02700	COG2210	Belongs to the sulfur carrier protein TusA family
M1M81_02705	COG1054	Belongs to the UPF0176 family
M1M81_02710	COG0425	Belongs to the sulfur carrier protein TusA family
M1M81_02710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M1M81_02720	COG0425	Belongs to the sulfur carrier protein TusA family
M1M81_02725	COG0730	response to heat
M1M81_02730	COG1794	racemase activity, acting on amino acids and derivatives
M1M81_02745	COG3621	Patatin-like phospholipase
M1M81_02755	COG0662	Cupin 2, conserved barrel domain protein
M1M81_02770	COG0277	FAD linked oxidase domain protein
M1M81_02795	COG0662	Cupin 2, conserved barrel domain protein
M1M81_02800	COG2318	DinB family
M1M81_02830	COG1064	alcohol dehydrogenase
M1M81_02835	COG0789	Transcriptional regulator
M1M81_02845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1M81_02855	COG2814	Major facilitator Superfamily
M1M81_02860	COG1309	transcriptional regulator
M1M81_02865	COG0697	spore germination
M1M81_02870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1M81_02875	COG5577	PFAM Coat F domain
M1M81_02885	COG1063	alcohol dehydrogenase
M1M81_02890	COG5577	PFAM Coat F domain
M1M81_02900	COG4585	Histidine kinase
M1M81_02905	COG2197	response regulator
M1M81_02910	COG2409	Drug exporters of the RND superfamily
M1M81_02915	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
M1M81_02920	COG0488	(ABC) transporter
M1M81_02925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1M81_02930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1M81_02940	COG2814	Major facilitator Superfamily
M1M81_02945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M1M81_02955	COG0730	response to heat
M1M81_02960	COG0456	acetyltransferase
M1M81_02965	COG0789	Transcriptional regulator
M1M81_02965	COG4978	Transcriptional regulator
M1M81_02970	COG0697	spore germination
M1M81_02975	COG1051	belongs to the nudix hydrolase family
M1M81_02980	COG2226	methyltransferase
M1M81_02985	COG0473	3-isopropylmalate dehydrogenase activity
M1M81_02990	COG1802	Transcriptional regulator
M1M81_02995	COG1819	glycosyl
M1M81_03010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1M81_03020	COG1388	LysM domain
M1M81_03025	COG2814	Major facilitator Superfamily
M1M81_03030	COG2188	Transcriptional regulator
M1M81_03035	COG2186	Transcriptional regulator
M1M81_03040	COG2807	transmembrane transport
M1M81_03045	COG2076	Multidrug Resistance protein
M1M81_03050	COG2076	Multidrug Resistance protein
M1M81_03055	COG1309	transcriptional regulator
M1M81_03060	COG0531	amino acid
M1M81_03070	COG3832	glyoxalase III activity
M1M81_03075	COG0604	alcohol dehydrogenase
M1M81_03080	COG2814	Major facilitator Superfamily
M1M81_03120	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
M1M81_03125	COG0802	atpase or kinase
M1M81_03130	COG1214	PFAM Peptidase M22, glycoprotease
M1M81_03135	COG0456	acetyltransferase
M1M81_03140	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
M1M81_03145	COG0488	(ABC) transporter
M1M81_03160	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
M1M81_03165	COG0805	protein transport
M1M81_03175	COG1266	CAAX protease self-immunity
M1M81_03220	COG0457	Tetratricopeptide repeat
M1M81_03225	COG1063	alcohol dehydrogenase
M1M81_03230	COG2211	Major facilitator Superfamily
M1M81_03235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M1M81_03245	COG1842	Phage shock protein A
M1M81_03250	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
M1M81_03255	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
M1M81_03260	COG4260	virion core protein, lumpy skin disease virus
M1M81_03265	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
M1M81_03265	COG2755	lipolytic protein G-D-S-L family
M1M81_03275	COG1595	DNA-templated transcription, initiation
M1M81_03280	COG1063	alcohol dehydrogenase
M1M81_03285	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
M1M81_03290	COG0823	Involved in the tonB-independent uptake of proteins
M1M81_03300	COG2132	Multicopper oxidase
M1M81_03305	COG1113	amino acid transport
M1M81_03310	COG0714	Associated with various cellular activities
M1M81_03315	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
M1M81_03320	COG1305	Transglutaminase-like
M1M81_03345	COG2252	PERMEase
M1M81_03350	COG3064	Membrane
M1M81_03370	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
M1M81_03375	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
M1M81_03380	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
M1M81_03385	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
M1M81_03390	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
M1M81_03405	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
M1M81_03415	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
M1M81_03420	COG0138	bifunctional purine biosynthesis protein purh
M1M81_03425	COG0151	Belongs to the GarS family
M1M81_03435	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
M1M81_03440	COG1470	cell adhesion involved in biofilm formation
M1M81_03445	COG4496	protein, YerC YecD
M1M81_03450	COG0069	glutamate synthase activity
M1M81_03460	COG0210	DNA helicase
M1M81_03470	COG4851	CamS sex pheromone cAM373 precursor
M1M81_03475	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M1M81_03480	COG1285	pathogenesis
M1M81_03485	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M1M81_03505	COG1309	transcriptional regulator
M1M81_03510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M1M81_03515	COG1597	lipid kinase activity
M1M81_03520	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
M1M81_03530	COG1131	(ABC) transporter
M1M81_03570	COG5444	nuclease activity
M1M81_03600	COG3546	catalase activity
M1M81_03605	COG0454	-acetyltransferase
M1M81_03615	COG2323	membrane
M1M81_03620	COG2329	Antibiotic biosynthesis monooxygenase
M1M81_03625	COG0346	lactoylglutathione lyase activity
M1M81_03630	COG1366	Belongs to the anti-sigma-factor antagonist family
M1M81_03635	COG5583	Uncharacterized small protein (DUF2292)
M1M81_03640	COG0196	riboflavin kinase activity
M1M81_03645	COG0670	Belongs to the BI1 family
M1M81_03650	COG1846	Transcriptional regulator
M1M81_03655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1M81_03665	COG2124	cytochrome p450
M1M81_03665	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
M1M81_03670	COG1368	sulfuric ester hydrolase activity
M1M81_03675	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
M1M81_03680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M1M81_03685	COG1442	glycosyl transferase family 8
M1M81_03690	COG1216	Glycosyl transferase, family 2
M1M81_03695	COG1442	glycosyl transferase family 8
M1M81_03700	COG2223	nitrite transmembrane transporter activity
M1M81_03705	COG0531	amino acid
M1M81_03710	COG1012	belongs to the aldehyde dehydrogenase family
M1M81_03715	COG0840	transmembrane signaling receptor activity
M1M81_03720	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_03725	COG0463	Glycosyl transferase, family 2
M1M81_03725	COG0457	Tetratricopeptide repeat
M1M81_03730	COG0488	(ABC) transporter
M1M81_03735	COG0789	Transcriptional regulator
M1M81_03740	COG2814	Major facilitator Superfamily
M1M81_03745	COG0488	(ABC) transporter
M1M81_03750	COG0513	Belongs to the DEAD box helicase family
M1M81_03755	COG0456	acetyltransferase
M1M81_03760	COG2130	NADP-dependent
M1M81_03775	COG3866	Pectate lyase
M1M81_03780	COG0471	metal ion transport
M1M81_03810	COG3290	protein histidine kinase activity
M1M81_03815	COG4565	transcriptional regulatory protein
M1M81_03820	COG3181	Tripartite tricarboxylate transporter family receptor
M1M81_03825	COG2851	Citrate transporter
M1M81_03830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1M81_03835	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
M1M81_03845	COG2258	MOSC domain
M1M81_03865	COG0024	Methionine aminopeptidase
M1M81_03870	COG1263	PTS System
M1M81_03870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M1M81_03880	COG1368	sulfuric ester hydrolase activity
M1M81_03890	COG0071	Belongs to the small heat shock protein (HSP20) family
M1M81_03905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M1M81_03905	COG1263	PTS System
M1M81_03910	COG0366	Alpha amylase catalytic
M1M81_03915	COG2188	Transcriptional regulator
M1M81_03920	COG0778	Nitroreductase
M1M81_03935	COG0737	Belongs to the 5'-nucleotidase family
M1M81_03940	COG0693	protein deglycase activity
M1M81_03945	COG1609	Transcriptional regulator
M1M81_03960	COG2814	Major facilitator Superfamily
M1M81_03970	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
M1M81_03975	COG4980	gas vesicle protein
M1M81_03980	COG1295	ribonuclease BN
M1M81_03985	COG0477	Major facilitator Superfamily
M1M81_03990	COG0387	Pfam Sodium calcium exchanger
M1M81_04000	COG0668	transmembrane transport
M1M81_04005	COG0535	radical SAM domain protein
M1M81_04015	COG0726	polysaccharide deacetylase
M1M81_04035	COG0745	RESPONSE REGULATOR receiver
M1M81_04040	COG2205	protein histidine kinase activity
M1M81_04045	COG2084	Dehydrogenase
M1M81_04055	COG0598	Magnesium transport protein CorA
M1M81_04060	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
M1M81_04065	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
M1M81_04080	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M1M81_04085	COG4637	Psort location Cytoplasmic, score
M1M81_04090	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M1M81_04095	COG0022	dehydrogenase e1 component
M1M81_04100	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1M81_04105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M1M81_04110	COG3284	Transcriptional regulator
M1M81_04120	COG1486	melibiose metabolic process
M1M81_04125	COG1737	Transcriptional regulator
M1M81_04130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M1M81_04130	COG1263	PTS System
M1M81_04135	COG5434	Belongs to the glycosyl hydrolase 28 family
M1M81_04140	COG5434	Belongs to the glycosyl hydrolase 28 family
M1M81_04145	COG1132	(ABC) transporter
M1M81_04150	COG1132	(ABC) transporter
M1M81_04155	COG2259	Doxx family
M1M81_04160	COG2514	catechol 2,3-dioxygenase activity
M1M81_04175	COG1695	Transcriptional regulator
M1M81_04180	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1M81_04185	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
M1M81_04190	COG3848	Pyruvate phosphate dikinase
M1M81_04190	COG0574	Belongs to the PEP-utilizing enzyme family
M1M81_04195	COG2732	(Barnase) inhibitor
M1M81_04200	COG2318	DinB family
M1M81_04205	COG2814	Major facilitator Superfamily
M1M81_04210	COG1846	Transcriptional regulator
M1M81_04215	COG0392	lysyltransferase activity
M1M81_04215	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
M1M81_04220	COG0384	phenazine biosynthesis protein PhzF
M1M81_04225	COG0778	Nitroreductase
M1M81_04240	COG1090	epimerase
M1M81_04255	COG2814	Major facilitator Superfamily
M1M81_04265	COG3591	Belongs to the peptidase S1B family
M1M81_04280	COG3103	Sh3 type 3 domain protein
M1M81_04285	COG5658	integral membrane protein
M1M81_04290	COG0596	Alpha beta hydrolase
M1M81_04295	COG0463	Glycosyl transferase, family 2
M1M81_04300	COG4485	Bacterial membrane protein, YfhO
M1M81_04305	COG1988	membrane-bound metal-dependent
M1M81_04310	COG1194	a g-specific adenine glycosylase
M1M81_04320	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_04340	COG1132	(ABC) transporter
M1M81_04345	COG4129	membrane
M1M81_04355	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
M1M81_04360	COG0735	belongs to the Fur family
M1M81_04475	COG3340	Belongs to the peptidase S51 family
M1M81_04485	COG0277	FAD linked oxidase domain protein
M1M81_04495	COG0747	negative chemotaxis
M1M81_04500	COG0601	transmembrane transport
M1M81_04505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M1M81_04510	COG0444	Belongs to the ABC transporter superfamily
M1M81_04515	COG4608	Belongs to the ABC transporter superfamily
M1M81_04520	COG0753	catalase activity
M1M81_04530	COG1116	anion transmembrane transporter activity
M1M81_04535	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1M81_04540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1M81_04560	COG1476	TRANSCRIPTIONal
M1M81_04570	COG3382	B3 4 domain protein
M1M81_04575	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
M1M81_04585	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
M1M81_04590	COG0789	Transcriptional regulator
M1M81_04595	COG1664	Polymer-forming cytoskeletal
M1M81_04600	COG1664	Polymer-forming cytoskeletal
M1M81_04605	COG2766	serine protein kinase
M1M81_04615	COG1846	Transcriptional regulator
M1M81_04620	COG1566	PFAM secretion protein HlyD family protein
M1M81_04625	COG2814	Major facilitator Superfamily
M1M81_04630	COG0655	NAD(P)H dehydrogenase (quinone) activity
M1M81_04645	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
M1M81_04650	COG1278	Cold shock
M1M81_04655	COG1464	Belongs to the NlpA lipoprotein family
M1M81_04660	COG3706	GGDEF domain
M1M81_04665	COG1823	symporter activity
M1M81_04685	COG5577	PFAM Coat F domain
M1M81_04690	COG0737	Belongs to the 5'-nucleotidase family
M1M81_04690	COG1525	nuclease
M1M81_04690	COG4085	toxin activity
M1M81_04695	COG3764	Sortase (surface protein transpeptidase)
M1M81_04700	COG0564	pseudouridine synthase activity
M1M81_04710	COG0517	IMP dehydrogenase activity
M1M81_04715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M1M81_04720	COG3153	acetyltransferase
M1M81_04720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M1M81_04725	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
M1M81_04730	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
M1M81_04735	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
M1M81_04745	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
M1M81_04750	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M1M81_04755	COG4585	Histidine kinase
M1M81_04755	COG2203	Gaf domain
M1M81_04760	COG2197	response regulator
M1M81_04765	COG0431	NADPH-dependent FMN reductase
M1M81_04780	COG1388	LysM domain
M1M81_04780	COG0791	NLP P60 protein
M1M81_04785	COG1959	2 iron, 2 sulfur cluster binding
M1M81_04795	COG2719	SpoVR family
M1M81_04800	COG1785	Belongs to the alkaline phosphatase family
M1M81_04805	COG0791	NLP P60 protein
M1M81_04805	COG1388	LysM domain
M1M81_04810	COG0583	DNA-binding transcription factor activity
M1M81_04815	COG0372	Belongs to the citrate synthase family
M1M81_04820	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_04825	COG0531	amino acid
M1M81_04830	COG0733	neurotransmitter:sodium symporter activity
M1M81_04845	COG1595	DNA-templated transcription, initiation
M1M81_04850	COG0204	Acyl-transferase
M1M81_04855	COG1253	flavin adenine dinucleotide binding
M1M81_04860	COG0789	Transcriptional regulator
M1M81_04865	COG0436	Aminotransferase
M1M81_04870	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M1M81_04875	COG1253	flavin adenine dinucleotide binding
M1M81_04880	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M1M81_04885	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M1M81_04890	COG0584	glycerophosphoryl diester phosphodiesterase
M1M81_04900	COG0668	transmembrane transport
M1M81_04905	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
M1M81_04910	COG0726	polysaccharide deacetylase
M1M81_04915	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M1M81_04920	COG3226	Transcriptional regulator
M1M81_04930	COG0589	response to stress
M1M81_04935	COG1132	(ABC) transporter
M1M81_04940	COG1132	(ABC) transporter
M1M81_04945	COG0702	epimerase
M1M81_04965	COG0189	ligase activity
M1M81_04970	COG0189	ligase activity
M1M81_04985	COG4335	DNA alkylation repair
M1M81_04990	COG0561	phosphatase activity
M1M81_04995	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M1M81_05005	COG0475	glutathione-regulated potassium exporter activity
M1M81_05010	COG0490	domain, Protein
M1M81_05020	COG1024	Enoyl-CoA hydratase
M1M81_05030	COG4152	abc transporter atp-binding protein
M1M81_05035	COG1668	transmembrane transport
M1M81_05040	COG0420	3'-5' exonuclease activity
M1M81_05045	COG4717	serine-type aminopeptidase activity
M1M81_05060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M1M81_05095	COG4980	gas vesicle protein
M1M81_05110	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
M1M81_05115	COG0537	adenosine 5'-monophosphoramidase activity
M1M81_05120	COG1131	(ABC) transporter
M1M81_05125	COG4473	ABC transporter
M1M81_05135	COG1473	amidohydrolase
M1M81_05140	COG3069	C4-dicarboxylate transmembrane transporter activity
M1M81_05145	COG2329	Antibiotic biosynthesis monooxygenase
M1M81_05150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M1M81_05160	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
M1M81_05165	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
M1M81_05170	COG1309	transcriptional regulator
M1M81_05175	COG1511	domain protein
M1M81_05180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M1M81_05190	COG1363	Peptidase, m42
M1M81_05195	COG1301	dicarboxylic acid transport
M1M81_05205	COG1234	tRNA 3'-trailer cleavage
M1M81_05210	COG0095	Lipoate-protein ligase
M1M81_05215	COG0702	epimerase
M1M81_05220	COG0318	PFAM AMP-dependent synthetase and ligase
M1M81_05230	COG0501	Belongs to the peptidase M48B family
M1M81_05235	COG1404	Belongs to the peptidase S8 family
M1M81_05240	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
M1M81_05245	COG0406	alpha-ribazole phosphatase activity
M1M81_05250	COG0183	Belongs to the thiolase family
M1M81_05255	COG0318	PFAM AMP-dependent synthetase and ligase
M1M81_05260	COG1268	BioY protein
M1M81_05265	COG0840	transmembrane signaling receptor activity
M1M81_05270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1M81_05270	COG0723	plastoquinol--plastocyanin reductase activity
M1M81_05275	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_05285	COG4903	ComK protein
M1M81_05295	COG5646	InterPro IPR014922
M1M81_05315	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M1M81_05330	COG0398	Pfam SNARE associated Golgi protein
M1M81_05335	COG0681	Belongs to the peptidase S26 family
M1M81_05340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1M81_05345	COG1846	Transcriptional regulator
M1M81_05350	COG3180	Ammonia monooxygenase
M1M81_05355	COG2814	Major facilitator Superfamily
M1M81_05365	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
M1M81_05370	COG2323	membrane
M1M81_05385	COG0420	3'-5' exonuclease activity
M1M81_05390	COG0419	ATPase involved in DNA repair
M1M81_05395	COG1403	HNH endonuclease
M1M81_05435	COG0179	Fumarylacetoacetate (FAA) hydrolase
M1M81_05450	COG0367	asparagine synthase
M1M81_05455	COG1562	ergosterol biosynthetic process
M1M81_05460	COG0534	Mate efflux family protein
M1M81_05465	COG1917	Cupin 2, conserved barrel domain protein
M1M81_05465	COG2207	Transcriptional regulator
M1M81_05475	COG2318	DinB family
M1M81_05480	COG1279	arginine transmembrane transporter activity
M1M81_05485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1M81_05490	COG1357	PFAM Pentapeptide repeats (8 copies)
M1M81_05495	COG2153	protein acetylation
M1M81_05500	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
M1M81_05500	COG0646	methionine synthase
M1M81_05510	COG2996	Protein conserved in bacteria
M1M81_05515	COG1744	ABC transporter substrate-binding protein PnrA-like
M1M81_05520	COG0840	transmembrane signaling receptor activity
M1M81_05525	COG2124	cytochrome p450
M1M81_05535	COG1307	EDD domain protein, DegV family
M1M81_05540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1M81_05560	COG0561	phosphatase activity
M1M81_05565	COG1073	alpha beta
M1M81_05570	COG2151	metal-sulfur cluster biosynthetic enzyme
M1M81_05580	COG0277	FAD linked oxidase domain protein
M1M81_05585	COG2271	Major facilitator Superfamily
M1M81_05595	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
M1M81_05605	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M1M81_05610	COG0505	Belongs to the CarA family
M1M81_05615	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
M1M81_05620	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
M1M81_05635	COG2267	carboxylic ester hydrolase activity
M1M81_05645	COG1744	ABC transporter substrate-binding protein PnrA-like
M1M81_05660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M1M81_05665	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M1M81_05670	COG5504	Zn-dependent protease
M1M81_05675	COG0444	Belongs to the ABC transporter superfamily
M1M81_05680	COG4608	Belongs to the ABC transporter superfamily
M1M81_05690	COG0601	transmembrane transport
M1M81_05695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M1M81_05705	COG0180	Tryptophanyl-tRNA synthetase
M1M81_05710	COG4166	transmembrane transport
M1M81_05715	COG0601	transmembrane transport
M1M81_05720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M1M81_05725	COG0444	Belongs to the ABC transporter superfamily
M1M81_05730	COG4608	Belongs to the ABC transporter superfamily
M1M81_05740	COG0456	acetyltransferase
M1M81_05745	COG1393	Belongs to the ArsC family
M1M81_05750	COG0861	Integral membrane protein TerC family
M1M81_05760	COG4862	establishment of competence for transformation
M1M81_05765	COG4469	Competence protein
M1M81_05770	COG1164	Oligoendopeptidase f
M1M81_05780	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
M1M81_05785	COG2346	COG2346, Truncated hemoglobins
M1M81_05790	COG0741	lytic transglycosylase activity
M1M81_05795	COG4116	CYTH
M1M81_05805	COG2357	RelA SpoT domain protein
M1M81_05810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
M1M81_05815	COG0564	pseudouridine synthase activity
M1M81_05825	COG0475	glutathione-regulated potassium exporter activity
M1M81_05825	COG0569	domain protein
M1M81_05830	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
M1M81_05835	COG0352	thiamine-phosphate diphosphorylase activity
M1M81_05840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1M81_05845	COG2104	thiamine diphosphate biosynthetic process
M1M81_05855	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M1M81_05860	COG0351	phosphomethylpyrimidine kinase
M1M81_05865	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
M1M81_05920	COG0210	DNA helicase
M1M81_05940	COG1131	(ABC) transporter
M1M81_05950	COG2153	protein acetylation
M1M81_05960	COG2382	esterase
M1M81_05965	COG0626	cystathionine gamma-synthase activity
M1M81_05970	COG0626	cystathionine gamma-synthase activity
M1M81_06000	COG5444	nuclease activity
M1M81_06010	COG0346	lactoylglutathione lyase activity
M1M81_06015	COG2367	Beta-lactamase
M1M81_06020	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
M1M81_06025	COG0477	Major facilitator Superfamily
M1M81_06030	COG1846	Transcriptional regulator
M1M81_06040	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
M1M81_06045	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M1M81_06050	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
M1M81_06055	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M1M81_06055	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M1M81_06060	COG1447	Phosphotransferase system cellobiose-specific component IIA
M1M81_06070	COG1349	DNA-binding transcription factor activity
M1M81_06090	COG1285	pathogenesis
M1M81_06105	COG2205	protein histidine kinase activity
M1M81_06115	COG3383	formate dehydrogenase (NAD+) activity
M1M81_06120	COG2427	Protein of unknown function (DUF1641)
M1M81_06125	COG2124	cytochrome p450
M1M81_06130	COG1819	glycosyl
M1M81_06140	COG1587	Uroporphyrinogen-III synthase
M1M81_06145	COG0390	transport system, permease component
M1M81_06150	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
M1M81_06155	COG0697	spore germination
M1M81_06160	COG4297	protein containing double-stranded beta helix domain
M1M81_06170	COG1252	NADH dehydrogenase
M1M81_06180	COG2211	Major facilitator Superfamily
M1M81_06185	COG1609	Transcriptional regulator
M1M81_06190	COG0246	Mannitol dehydrogenase
M1M81_06195	COG2721	sulfolactate sulfo-lyase activity
M1M81_06200	COG0745	RESPONSE REGULATOR receiver
M1M81_06205	COG2205	protein histidine kinase activity
M1M81_06205	COG2770	Histidine kinase
M1M81_06225	COG4585	Histidine kinase
M1M81_06230	COG2197	response regulator
M1M81_06265	COG0730	response to heat
M1M81_06270	COG2318	DinB family
M1M81_06275	COG0457	Tetratricopeptide repeat
M1M81_06285	COG1388	LysM domain
M1M81_06285	COG5632	N-Acetylmuramoyl-L-alanine amidase
M1M81_06285	COG3409	Peptidoglycan-binding domain 1 protein
M1M81_06295	COG4195	phage-related replication protein
M1M81_06300	COG2856	Zn peptidase
M1M81_06305	COG1396	sequence-specific DNA binding
M1M81_06315	COG1522	sequence-specific DNA binding
M1M81_06320	COG1484	DNA-dependent DNA replication
M1M81_06340	COG1595	DNA-templated transcription, initiation
M1M81_06345	COG5484	DNA packaging
M1M81_06345	COG3728	DNA packaging
M1M81_06350	COG1783	phage Terminase large subunit
M1M81_06355	COG5518	Phage portal protein
M1M81_06360	COG0338	D12 class N6 adenine-specific DNA methyltransferase
M1M81_06365	COG4653	Phage capsid family
M1M81_06415	COG3953	SLT domain
M1M81_06415	COG5412	phage tail tape measure protein
M1M81_06415	COG3953	SLT domain
M1M81_06415	COG5412	phage tail tape measure protein
M1M81_06415	COG3953	SLT domain
M1M81_06415	COG5412	phage tail tape measure protein
M1M81_06420	COG1652	LysM domain
M1M81_06425	COG4193	domain, Protein
M1M81_06435	COG3628	GPW Gp25 family protein
M1M81_06440	COG3299	homolog of phage Mu protein gp47
M1M81_06445	COG3778	Protein conserved in bacteria
M1M81_06485	COG3409	Peptidoglycan-binding domain 1 protein
M1M81_06485	COG5632	N-Acetylmuramoyl-L-alanine amidase
M1M81_06505	COG0306	phosphate transporter
M1M81_06510	COG1392	Phosphate transport regulator
M1M81_06515	COG0531	amino acid
M1M81_06520	COG0346	lactoylglutathione lyase activity
M1M81_06525	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
M1M81_06530	COG0463	Glycosyl transferase, family 2
M1M81_06540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M1M81_06545	COG0477	Major facilitator Superfamily
M1M81_06550	COG2362	D-Aminopeptidase
M1M81_06555	COG0601	transmembrane transport
M1M81_06560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M1M81_06565	COG0444	Belongs to the ABC transporter superfamily
M1M81_06570	COG4166	transmembrane transport
M1M81_06575	COG1619	proteins homologs of microcin C7 resistance protein MccF
M1M81_06580	COG4948	Mandelate Racemase Muconate Lactonizing
M1M81_06585	COG0791	NLP P60 protein
M1M81_06590	COG4608	Belongs to the ABC transporter superfamily
M1M81_06595	COG2706	6-phosphogluconolactonase activity
M1M81_06600	COG1834	amidinotransferase
M1M81_06605	COG1607	acyl-coa hydrolase
M1M81_06610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1M81_06615	COG2076	Multidrug Resistance protein
M1M81_06620	COG2076	Multidrug Resistance protein
M1M81_06625	COG0788	formyltetrahydrofolate deformylase activity
M1M81_06630	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
M1M81_06640	COG1764	response to oxidative stress
M1M81_06645	COG1846	Transcriptional regulator
M1M81_06650	COG1764	response to oxidative stress
M1M81_06665	COG0463	Glycosyl transferase, family 2
M1M81_06665	COG0457	Tetratricopeptide repeat
M1M81_06690	COG1404	Belongs to the peptidase S8 family
M1M81_06695	COG1366	Belongs to the anti-sigma-factor antagonist family
M1M81_06700	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
M1M81_06705	COG1122	ATPase activity
M1M81_06710	COG4721	ABC-type cobalt transport system, permease component
M1M81_06715	COG3858	chitin binding
M1M81_06715	COG1388	LysM domain
M1M81_06725	COG2239	Acts as a magnesium transporter
M1M81_06730	COG0789	Transcriptional regulator
M1M81_06745	COG1846	Transcriptional regulator
M1M81_06750	COG0726	polysaccharide deacetylase
M1M81_06755	COG1793	dna ligase
M1M81_06755	COG3285	dna ligase
M1M81_06760	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
M1M81_06765	COG0586	Pfam SNARE associated Golgi protein
M1M81_06775	COG1191	sigma factor activity
M1M81_06800	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M1M81_06805	COG2323	membrane
M1M81_06815	COG3594	Acyltransferase
M1M81_06820	COG5002	protein histidine kinase activity
M1M81_06825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M1M81_06845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M1M81_06850	COG0436	Aminotransferase
M1M81_06880	COG3852	Histidine kinase
M1M81_06885	COG1846	Transcriptional regulator
M1M81_06890	COG1360	Flagellar Motor Protein
M1M81_06895	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
M1M81_06900	COG0542	response to heat
M1M81_06905	COG3949	Membrane
M1M81_06920	COG0720	synthase
M1M81_06925	COG0602	queuosine metabolic process
M1M81_06940	COG1733	regulation of RNA biosynthetic process
M1M81_06945	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_06960	COG4873	Protein conserved in bacteria
M1M81_06970	COG3773	Cell wall hydrolase
M1M81_06975	COG2244	polysaccharide biosynthetic process
M1M81_06980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M1M81_06985	COG2217	Heavy metal translocating P-type atpase
M1M81_06990	COG0006	proline dipeptidase activity
M1M81_06995	COG1609	Transcriptional regulator
M1M81_07000	COG3711	transcriptional antiterminator
M1M81_07005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M1M81_07005	COG2190	(PTS) system
M1M81_07005	COG1263	PTS System
M1M81_07010	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M1M81_07015	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
M1M81_07025	COG1533	DNA photolyase activity
M1M81_07030	COG0840	transmembrane signaling receptor activity
M1M81_07035	COG2084	Dehydrogenase
M1M81_07040	COG2340	Cysteine-rich secretory protein family
M1M81_07045	COG0768	penicillin binding
M1M81_07050	COG4191	Histidine kinase
M1M81_07055	COG0436	Aminotransferase
M1M81_07065	COG0784	Response regulator, receiver
M1M81_07065	COG0835	chemotaxis
M1M81_07075	COG2814	Major facilitator Superfamily
M1M81_07080	COG1376	ErfK ybiS ycfS ynhG family protein
M1M81_07085	COG1408	metallophosphoesterase
M1M81_07090	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_07100	COG2200	EAL domain
M1M81_07105	COG4703	Protein of unknown function (DUF1797)
M1M81_07110	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
M1M81_07120	COG0517	IMP dehydrogenase activity
M1M81_07125	COG0583	DNA-binding transcription factor activity
M1M81_07130	COG0716	FMN binding
M1M81_07140	COG0716	FMN binding
M1M81_07160	COG0668	transmembrane transport
M1M81_07165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M1M81_07185	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M1M81_07190	COG0303	'Molybdopterin
M1M81_07195	COG1763	Mo-molybdopterin cofactor biosynthetic process
M1M81_07200	COG0314	molybdopterin synthase activity
M1M81_07205	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
M1M81_07215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1M81_07220	COG1136	(ABC) transporter
M1M81_07225	COG0577	efflux transmembrane transporter activity
M1M81_07230	COG1349	DNA-binding transcription factor activity
M1M81_07235	COG1105	Belongs to the carbohydrate kinase PfkB family
M1M81_07240	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M1M81_07240	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M1M81_07240	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M1M81_07245	COG0681	Belongs to the peptidase S26 family
M1M81_07255	COG0488	(ABC) transporter
M1M81_07260	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
M1M81_07265	COG2309	aminopeptidase activity
M1M81_07275	COG1077	Cell shape determining protein MreB Mrl
M1M81_07280	COG2002	toxin-antitoxin pair type II binding
M1M81_07285	COG3852	Histidine kinase
M1M81_07290	COG2105	PFAM AIG2 family protein
M1M81_07290	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
M1M81_07295	COG0569	domain protein
M1M81_07305	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
M1M81_07315	COG0561	phosphatase activity
M1M81_07320	COG0242	peptide deformylase activity
M1M81_07330	COG0497	DNA recombination
M1M81_07335	COG2070	2-Nitropropane dioxygenase
M1M81_07335	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M1M81_07340	COG4221	oxidoreductase activity
M1M81_07340	COG3321	synthase
M1M81_07340	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_07340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1M81_07345	COG4221	oxidoreductase activity
M1M81_07345	COG0300	oxidoreductase activity
M1M81_07345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1M81_07345	COG3321	synthase
M1M81_07350	COG4221	oxidoreductase activity
M1M81_07350	COG3321	synthase
M1M81_07350	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_07350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1M81_07355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1M81_07355	COG3321	synthase
M1M81_07355	COG4221	oxidoreductase activity
M1M81_07355	COG0300	oxidoreductase activity
M1M81_07360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1M81_07360	COG0300	oxidoreductase activity
M1M81_07360	COG3321	synthase
M1M81_07360	COG4221	oxidoreductase activity
M1M81_07365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1M81_07365	COG3321	synthase
M1M81_07365	COG4221	oxidoreductase activity
M1M81_07365	COG0300	oxidoreductase activity
M1M81_07370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1M81_07370	COG3321	synthase
M1M81_07370	COG4221	oxidoreductase activity
M1M81_07370	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_07375	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1M81_07380	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M1M81_07385	COG0022	dehydrogenase e1 component
M1M81_07390	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1M81_07395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M1M81_07400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M1M81_07415	COG1982	Orn Lys Arg decarboxylase major
M1M81_07435	COG0483	inositol monophosphate 1-phosphatase activity
M1M81_07445	COG3227	Zinc metalloprotease (Elastase)
M1M81_07450	COG1595	DNA-templated transcription, initiation
M1M81_07470	COG1217	gtp-binding protein TYPA
M1M81_07480	COG4896	Protein conserved in bacteria
M1M81_07490	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
M1M81_07495	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
M1M81_07500	COG2066	Belongs to the glutaminase family
M1M81_07510	COG0772	Belongs to the SEDS family
M1M81_07515	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
M1M81_07530	COG2010	Cytochrome c
M1M81_07530	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
M1M81_07535	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
M1M81_07540	COG1845	cytochrome c oxidase, subunit III
M1M81_07545	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
M1M81_07550	COG3336	cytochrome c oxidase
M1M81_07560	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
M1M81_07565	COG2340	Cysteine-rich secretory protein family
M1M81_07580	COG3679	Belongs to the UPF0342 family
M1M81_07590	COG0742	ribosomal rna small subunit methyltransferase
M1M81_07600	COG3314	Sporulation integral membrane protein YlbJ
M1M81_07605	COG1752	Esterase of the alpha-beta hydrolase superfamily
M1M81_07610	COG3480	Lon protease (S16) C-terminal proteolytic domain
M1M81_07620	COG1399	metal-binding, possibly nucleic acid-binding protein
M1M81_07640	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
M1M81_07660	COG4839	cell division protein FtsL
M1M81_07665	COG0768	penicillin binding
M1M81_07670	COG0768	penicillin binding
M1M81_07690	COG0772	Belongs to the SEDS family
M1M81_07705	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
M1M81_07710	COG0849	cell division
M1M81_07715	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
M1M81_07720	COG4412	M6 family metalloprotease domain protein
M1M81_07720	COG1404	Belongs to the peptidase S8 family
M1M81_07730	COG1191	sigma factor activity
M1M81_07735	COG1191	sigma factor activity
M1M81_07740	COG1119	ATPase activity
M1M81_07745	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M1M81_07750	COG1873	PFAM PRC-barrel domain
M1M81_07755	COG1496	oxidoreductase activity
M1M81_07760	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
M1M81_07770	COG0762	integral membrane protein
M1M81_07775	COG2302	S4 RNA-binding domain
M1M81_07780	COG3599	regulation of cell shape
M1M81_07785	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
M1M81_07790	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
M1M81_07800	COG0564	pseudouridine synthase activity
M1M81_07810	COG2233	PERMEase
M1M81_07820	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
M1M81_07825	COG0505	Belongs to the CarA family
M1M81_07830	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
M1M81_07845	COG0284	orotidine-5'-phosphate decarboxylase activity
M1M81_07850	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
M1M81_07860	COG0306	phosphate transporter
M1M81_07875	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
M1M81_07880	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
M1M81_07885	COG1648	precorrin-2 dehydrogenase activity
M1M81_07895	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
M1M81_07900	COG1561	YicC-like family, N-terminal region
M1M81_07910	COG0194	GDP metabolic process
M1M81_07920	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M1M81_07925	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
M1M81_07930	COG0242	peptide deformylase activity
M1M81_07940	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
M1M81_07940	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
M1M81_07950	COG0631	protein serine/threonine phosphatase activity
M1M81_07955	COG2815	serine threonine protein kinase
M1M81_07955	COG0515	serine threonine protein kinase
M1M81_07965	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
M1M81_07970	COG1564	THIamine pyrophosphokinase
M1M81_07985	COG1302	Protein conserved in bacteria
M1M81_07990	COG1461	Dihydroxyacetone kinase
M1M81_07995	COG1760	l-serine dehydratase
M1M81_08000	COG1760	l-serine dehydratase
M1M81_08005	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
M1M81_08020	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M1M81_08025	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_08040	COG1196	nuclear chromosome segregation
M1M81_08045	COG0552	protein localization to endoplasmic reticulum
M1M81_08060	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
M1M81_08070	COG1837	Belongs to the UPF0109 family
M1M81_08095	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
M1M81_08110	COG2257	FlhB HrpN YscU SpaS Family
M1M81_08120	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
M1M81_08125	COG0758	DNA mediated transformation
M1M81_08130	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M1M81_08140	COG4974	Belongs to the 'phage' integrase family
M1M81_08160	COG1815	bacterial-type flagellum-dependent cell motility
M1M81_08165	COG1558	bacterial-type flagellum-dependent cell motility
M1M81_08170	COG1677	Flagellar hook-basal body complex protein FliE
M1M81_08175	COG1766	The M ring may be actively involved in energy transduction
M1M81_08180	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M1M81_08185	COG1317	bacterial-type flagellum organization
M1M81_08190	COG1157	protein secretion by the type III secretion system
M1M81_08195	COG2882	bacterial-type flagellum organization
M1M81_08200	COG3334	PFAM MgtE intracellular
M1M81_08205	COG3144	bacterial-type flagellum assembly
M1M81_08210	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
M1M81_08215	COG4786	Flagellar basal body rod
M1M81_08220	COG1582	Flagellar protein (FlbD)
M1M81_08225	COG1580	Controls the rotational direction of flagella during chemotaxis
M1M81_08230	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M1M81_08235	COG1776	CheC inhibitor of MCP methylation
M1M81_08235	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M1M81_08240	COG2201	protein-glutamate methylesterase activity
M1M81_08245	COG3190	flagellar
M1M81_08250	COG1338	Plays a role in the flagellum-specific transport system
M1M81_08255	COG1987	bacterial-type flagellum assembly
M1M81_08260	COG1684	flagellar biosynthetic protein fliR
M1M81_08265	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M1M81_08270	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M1M81_08275	COG1419	protein localization to endoplasmic reticulum
M1M81_08280	COG0455	bacterial-type flagellum organization
M1M81_08285	COG2201	protein-glutamate methylesterase activity
M1M81_08290	COG0643	Histidine kinase
M1M81_08290	COG2198	Histidine kinase
M1M81_08295	COG0835	chemotaxis
M1M81_08300	COG1776	CheC inhibitor of MCP methylation
M1M81_08310	COG1191	sigma factor activity
M1M81_08340	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
M1M81_08345	COG4589	Belongs to the CDS family
M1M81_08355	COG0750	zinc metalloprotease
M1M81_08375	COG0195	Participates in both transcription termination and antitermination
M1M81_08380	COG2740	Nucleic-acid-binding protein implicated in transcription termination
M1M81_08385	COG1358	cellular component organization or biogenesis
M1M81_08395	COG1550	Protein conserved in bacteria
M1M81_08410	COG0196	riboflavin kinase activity
M1M81_08425	COG0726	polysaccharide deacetylase
M1M81_08430	COG0612	Peptidase, M16
M1M81_08435	COG1873	PFAM PRC-barrel domain
M1M81_08440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M1M81_08445	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M1M81_08450	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
M1M81_08455	COG0527	aspartate kinase activity
M1M81_08465	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
M1M81_08470	COG0740	serine-type endopeptidase activity
M1M81_08480	COG1674	ftsk spoiiie
M1M81_08480	COG4980	gas vesicle protein
M1M81_08485	COG2188	Transcriptional regulator
M1M81_08490	COG2814	Major facilitator Superfamily
M1M81_08495	COG1846	Transcriptional regulator
M1M81_08500	COG1033	growth of symbiont in host cell
M1M81_08500	COG2409	Drug exporters of the RND superfamily
M1M81_08505	COG0612	Peptidase, M16
M1M81_08510	COG0612	Peptidase, M16
M1M81_08515	COG0300	oxidoreductase activity
M1M81_08530	COG1426	Protein conserved in bacteria
M1M81_08535	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
M1M81_08550	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1M81_08560	COG1692	metallophosphoesterase
M1M81_08565	COG2359	stage V sporulation protein S
M1M81_08585	COG4550	Control of competence regulator ComK, YlbF/YmcA
M1M81_08630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1M81_08635	COG3425	synthase
M1M81_08640	COG1024	Enoyl-CoA hydratase
M1M81_08645	COG1024	Enoyl-CoA hydratase
M1M81_08650	COG0300	oxidoreductase activity
M1M81_08650	COG0318	PFAM AMP-dependent synthetase and ligase
M1M81_08650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1M81_08650	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_08650	COG3321	synthase
M1M81_08655	COG3321	synthase
M1M81_08655	COG0300	oxidoreductase activity
M1M81_08655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1M81_08655	COG4221	oxidoreductase activity
M1M81_08660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1M81_08660	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_08660	COG3321	synthase
M1M81_08660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1M81_08660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1M81_08660	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_08660	COG3321	synthase
M1M81_08660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M1M81_08660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1M81_08660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M1M81_08665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1M81_08665	COG4221	oxidoreductase activity
M1M81_08665	COG3321	synthase
M1M81_08665	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_08670	COG3321	synthase
M1M81_08670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1M81_08670	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
M1M81_08670	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
M1M81_08675	COG2124	cytochrome p450
M1M81_08680	COG3209	COG3209 Rhs family protein
M1M81_08685	COG3619	membrane
M1M81_08695	COG1404	Belongs to the peptidase S8 family
M1M81_08705	COG4195	phage-related replication protein
M1M81_08710	COG1764	response to oxidative stress
M1M81_08720	COG2076	Multidrug Resistance protein
M1M81_08760	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M1M81_08765	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M1M81_08770	COG4112	unkown
M1M81_08775	COG0860	N-Acetylmuramoyl-L-alanine amidase
M1M81_08780	COG0464	growth
M1M81_08785	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
M1M81_08790	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
M1M81_08795	COG0789	Transcriptional regulator
M1M81_08800	COG0174	glutamine synthetase
M1M81_08845	COG2211	Major facilitator Superfamily
M1M81_08850	COG3507	Belongs to the glycosyl hydrolase 43 family
M1M81_08865	COG1070	Carbohydrate kinase
M1M81_08870	COG0574	Belongs to the PEP-utilizing enzyme family
M1M81_08870	COG3848	Pyruvate phosphate dikinase
M1M81_08890	COG2318	DinB family
M1M81_08895	COG1064	alcohol dehydrogenase
M1M81_08900	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
M1M81_08900	COG4451	ribulose bisphosphate carboxylase, small
M1M81_08945	COG3397	chitin binding
M1M81_08965	COG5434	Belongs to the glycosyl hydrolase 28 family
M1M81_08970	COG0756	dUTP diphosphatase activity
M1M81_08980	COG4195	phage-related replication protein
M1M81_09015	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
M1M81_09025	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
M1M81_09045	COG0785	Cytochrome C biogenesis protein
M1M81_09050	COG2201	protein-glutamate methylesterase activity
M1M81_09055	COG4846	Membrane protein involved in cytochrome C biogenesis
M1M81_09065	COG0071	Belongs to the small heat shock protein (HSP20) family
M1M81_09080	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
M1M81_09085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M1M81_09105	COG0824	Thioesterase
M1M81_09115	COG4841	protein insertion into membrane
M1M81_09125	COG1832	CoA-binding protein
M1M81_09130	COG0187	DNA topoisomerase II activity
M1M81_09135	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
M1M81_09145	COG1115	amino acid carrier protein
M1M81_09155	COG1063	alcohol dehydrogenase
M1M81_09160	COG0800	Aldolase
M1M81_09165	COG1312	Catalyzes the dehydration of D-mannonate
M1M81_09170	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_09175	COG1609	Transcriptional regulator
M1M81_09180	COG2271	Major facilitator Superfamily
M1M81_09225	COG2205	protein histidine kinase activity
M1M81_09230	COG0745	RESPONSE REGULATOR receiver
M1M81_09240	COG3507	Belongs to the glycosyl hydrolase 43 family
M1M81_09265	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_09270	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M1M81_09275	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M1M81_09280	COG2610	gluconate transmembrane transporter activity
M1M81_09285	COG2124	cytochrome p450
M1M81_09305	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
M1M81_09315	COG2246	polysaccharide biosynthetic process
M1M81_09325	COG0586	Pfam SNARE associated Golgi protein
M1M81_09330	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
M1M81_09335	COG1024	Enoyl-CoA hydratase
M1M81_09340	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
M1M81_09345	COG0511	ligase activity, forming carbon-carbon bonds
M1M81_09350	COG0439	Biotin carboxylase
M1M81_09355	COG0318	PFAM AMP-dependent synthetase and ligase
M1M81_09360	COG1960	acyl-CoA dehydrogenase activity
M1M81_09365	COG1649	PFAM Uncharacterised BCR, COG1649
M1M81_09375	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
M1M81_09375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1M81_09380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1M81_09385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1M81_09390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1M81_09395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1M81_09400	COG2027	D-alanyl-D-alanine carboxypeptidase
M1M81_09405	COG2017	converts alpha-aldose to the beta-anomer
M1M81_09410	COG0534	Mate efflux family protein
M1M81_09425	COG0582	viral genome integration into host DNA
M1M81_09430	COG0166	Belongs to the GPI family
M1M81_09435	COG0405	Gamma-glutamyltransferase
M1M81_09440	COG2814	Major facilitator Superfamily
M1M81_09445	COG0640	Transcriptional regulator
M1M81_09450	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
M1M81_09460	COG0604	alcohol dehydrogenase
M1M81_09465	COG0493	'glutamate synthase
M1M81_09470	COG0067	glutamate synthase
M1M81_09470	COG0070	glutamate synthase
M1M81_09470	COG0069	glutamate synthase activity
M1M81_09475	COG0583	DNA-binding transcription factor activity
M1M81_09480	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
M1M81_09495	COG0300	oxidoreductase activity
M1M81_09500	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
M1M81_09510	COG2814	Major facilitator Superfamily
M1M81_09515	COG1070	Carbohydrate kinase
M1M81_09520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M1M81_09525	COG0243	molybdopterin cofactor binding
M1M81_09555	COG5444	nuclease activity
M1M81_09560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1M81_09565	COG2207	Transcriptional regulator
M1M81_09565	COG0662	Cupin 2, conserved barrel domain protein
M1M81_09570	COG1309	transcriptional regulator
M1M81_09575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1M81_09585	COG0640	Transcriptional regulator
M1M81_09590	COG0741	lytic transglycosylase activity
M1M81_09595	COG2322	membrane
M1M81_09610	COG1619	proteins homologs of microcin C7 resistance protein MccF
M1M81_09620	COG1388	LysM domain
M1M81_09620	COG3584	3D domain protein
M1M81_09625	COG0514	ATP-dependent DNA helicase (RecQ)
M1M81_09635	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
M1M81_09640	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
M1M81_09655	COG0071	Belongs to the small heat shock protein (HSP20) family
M1M81_09685	COG1012	belongs to the aldehyde dehydrogenase family
M1M81_09690	COG1657	PFAM Prenyltransferase squalene oxidase
M1M81_09695	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M1M81_09700	COG0733	neurotransmitter:sodium symporter activity
M1M81_09705	COG0385	Bile acid
M1M81_09710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1M81_09715	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1M81_09725	COG4548	von Willebrand factor, type A
M1M81_09730	COG0714	Associated with various cellular activities
M1M81_09735	COG2032	superoxide dismutase activity
M1M81_09740	COG0791	NLP P60 protein
M1M81_09740	COG1388	LysM domain
M1M81_09745	COG1819	glycosyl
M1M81_09750	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
M1M81_09755	COG0534	Mate efflux family protein
M1M81_09760	COG1366	Belongs to the anti-sigma-factor antagonist family
M1M81_09765	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M1M81_09770	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M1M81_09780	COG2962	Rard protein
M1M81_09795	COG1942	4-Oxalocrotonate Tautomerase
M1M81_09805	COG1733	regulation of RNA biosynthetic process
M1M81_09810	COG0778	Nitroreductase
M1M81_09815	COG0400	carboxylic ester hydrolase activity
M1M81_09820	COG0346	lactoylglutathione lyase activity
M1M81_09830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M1M81_09840	COG2723	6-phospho-beta-galactosidase activity
M1M81_09845	COG2188	Transcriptional regulator
M1M81_09850	COG0793	Belongs to the peptidase S41A family
M1M81_09850	COG3409	Peptidoglycan-binding domain 1 protein
M1M81_09855	COG2226	methyltransferase
M1M81_09865	COG1876	peptidase activity
M1M81_09885	COG0671	phosphoesterase, PA-phosphatase related
M1M81_09915	COG1509	lysine 2,3-aminomutase activity
M1M81_09920	COG0456	acetyltransferase
M1M81_09925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M1M81_09930	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M1M81_09935	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M1M81_09940	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
M1M81_09945	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
M1M81_09955	COG0456	acetyltransferase
M1M81_09960	COG0463	Glycosyl transferase, family 2
M1M81_09975	COG4641	Protein conserved in bacteria
M1M81_09985	COG1086	Polysaccharide biosynthesis protein
M1M81_10020	COG0457	Tetratricopeptide repeat
M1M81_10030	COG3391	amine dehydrogenase activity
M1M81_10050	COG5444	nuclease activity
M1M81_10055	COG4282	regulation of fungal-type cell wall biogenesis
M1M81_10060	COG1525	nuclease
M1M81_10085	COG1846	Transcriptional regulator
M1M81_10090	COG4698	Protein conserved in bacteria
M1M81_10095	COG2755	lipolytic protein G-D-S-L family
M1M81_10100	COG1999	signal sequence binding
M1M81_10110	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
M1M81_10115	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
M1M81_10120	COG1272	protein, Hemolysin III
M1M81_10125	COG0204	Acyl-transferase
M1M81_10130	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M1M81_10145	COG2136	Putative SAM-dependent methyltransferase
M1M81_10145	COG2521	methyltransferase
M1M81_10160	COG1413	lyase activity
M1M81_10165	COG1418	mRNA catabolic process
M1M81_10170	COG0386	Belongs to the glutathione peroxidase family
M1M81_10180	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
M1M81_10190	COG1278	Cold shock
M1M81_10210	COG0328	RNA-DNA hybrid ribonuclease activity
M1M81_10215	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
M1M81_10220	COG0328	RNA-DNA hybrid ribonuclease activity
M1M81_10230	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M1M81_10245	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
M1M81_10255	COG1755	Isoprenylcysteine carboxyl methyltransferase
M1M81_10260	COG3424	synthase
M1M81_10285	COG1335	isochorismatase
M1M81_10295	COG2233	PERMEase
M1M81_10305	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
M1M81_10310	COG1199	ATP-dependent helicase activity
M1M81_10325	COG0116	Belongs to the methyltransferase superfamily
M1M81_10355	COG3359	exonuclease
M1M81_10360	COG1205	dead DEAH box helicase
M1M81_10360	COG1111	helicase
M1M81_10365	COG2190	(PTS) system
M1M81_10370	COG0071	Belongs to the small heat shock protein (HSP20) family
M1M81_10410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M1M81_10410	COG4499	WXG100 protein secretion system (Wss), protein YukC
M1M81_10420	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
M1M81_10425	COG3935	DnaD domain protein
M1M81_10435	COG0436	Aminotransferase
M1M81_10440	COG5353	protein conserved in bacteria
M1M81_10450	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M1M81_10450	COG1199	ATP-dependent helicase activity
M1M81_10480	COG0438	transferase activity, transferring glycosyl groups
M1M81_10485	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M1M81_10500	COG1694	Mazg nucleotide pyrophosphohydrolase
M1M81_10505	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1M81_10520	COG4347	Protein of unknown function (DUF1405)
M1M81_10525	COG2010	Cytochrome c
M1M81_10525	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
M1M81_10530	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
M1M81_10535	COG0723	plastoquinol--plastocyanin reductase activity
M1M81_10550	COG0457	Tetratricopeptide repeat
M1M81_10560	COG0287	Prephenate dehydrogenase
M1M81_10595	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
M1M81_10600	COG4401	Chorismate mutase type I
M1M81_10615	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
M1M81_10620	COG0105	UTP biosynthetic process
M1M81_10625	COG0142	geranyltranstransferase activity
M1M81_10635	COG0142	geranyltranstransferase activity
M1M81_10650	COG0776	regulation of translation
M1M81_10655	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
M1M81_10695	COG0539	negative regulation of cytoplasmic translation
M1M81_10710	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
M1M81_10715	COG2959	enzyme of heme biosynthesis
M1M81_10720	COG3409	Peptidoglycan-binding domain 1 protein
M1M81_10720	COG3773	Cell wall hydrolase
M1M81_10725	COG2339	peptidase activity
M1M81_10730	COG0492	ferredoxin-NADP+ reductase activity
M1M81_10735	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M1M81_10740	COG4862	establishment of competence for transformation
M1M81_10745	COG1408	metallophosphoesterase
M1M81_10755	COG1388	LysM domain
M1M81_10760	COG1266	CAAX protease self-immunity
M1M81_10765	COG0514	ATP-dependent DNA helicase (RecQ)
M1M81_10770	COG4955	Helix-turn-helix domain
M1M81_10775	COG1141	Ferredoxin
M1M81_10780	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
M1M81_10785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M1M81_10795	COG1595	DNA-templated transcription, initiation
M1M81_10800	COG5002	protein histidine kinase activity
M1M81_10805	COG0745	RESPONSE REGULATOR receiver
M1M81_10810	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M1M81_10815	COG1333	cytochrome c biogenesis protein
M1M81_10820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M1M81_10825	COG1187	pseudouridine synthase activity
M1M81_10830	COG0700	Nucleoside recognition
M1M81_10835	COG2715	membrane protein required for spore maturation
M1M81_10840	COG1686	Belongs to the peptidase S11 family
M1M81_10865	COG1547	Domain of unknown function (DUF309)
M1M81_10870	COG0456	acetyltransferase
M1M81_10885	COG0307	riboflavin synthase, alpha
M1M81_10890	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M1M81_10890	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M1M81_10900	COG0681	Belongs to the peptidase S26 family
M1M81_10910	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
M1M81_10915	COG4086	secreted protein
M1M81_10920	COG0019	diaminopimelate decarboxylase activity
M1M81_10925	COG0697	spore germination
M1M81_10940	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M1M81_10960	COG1191	sigma factor activity
M1M81_10970	COG1366	Belongs to the anti-sigma-factor antagonist family
M1M81_10975	COG1686	Belongs to the peptidase S11 family
M1M81_10980	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
M1M81_10985	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
M1M81_10990	COG4974	Belongs to the 'phage' integrase family
M1M81_11000	COG0735	belongs to the Fur family
M1M81_11005	COG1300	Membrane
M1M81_11020	COG0281	malic enzyme
M1M81_11025	COG1757	Na H antiporter
M1M81_11030	COG1027	Aspartate ammonia-lyase
M1M81_11035	COG0252	asparaginase activity
M1M81_11040	COG1396	sequence-specific DNA binding
M1M81_11045	COG1379	DNA repair
M1M81_11050	COG0494	nUDIX hydrolase
M1M81_11060	COG0667	Aldo Keto reductase
M1M81_11070	COG1073	alpha beta
M1M81_11080	COG4918	Iron-sulphur cluster biosynthesis
M1M81_11085	COG0456	acetyltransferase
M1M81_11085	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
M1M81_11090	COG2329	Antibiotic biosynthesis monooxygenase
M1M81_11095	COG0456	acetyltransferase
M1M81_11100	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
M1M81_11115	COG0628	permease
M1M81_11125	COG0346	lactoylglutathione lyase activity
M1M81_11135	COG3048	D-serine ammonia-lyase activity
M1M81_11140	COG0300	oxidoreductase activity
M1M81_11145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1M81_11150	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M1M81_11155	COG1024	Enoyl-CoA hydratase
M1M81_11160	COG3425	synthase
M1M81_11165	COG2124	cytochrome p450
M1M81_11170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1M81_11170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1M81_11170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M1M81_11170	COG3321	synthase
M1M81_11170	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_11175	COG3321	synthase
M1M81_11175	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_11175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1M81_11175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M1M81_11175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1M81_11180	COG3321	synthase
M1M81_11180	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_11180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1M81_11180	COG0300	oxidoreductase activity
M1M81_11180	COG0318	PFAM AMP-dependent synthetase and ligase
M1M81_11185	COG3321	synthase
M1M81_11185	COG0318	PFAM AMP-dependent synthetase and ligase
M1M81_11185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1M81_11185	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_11185	COG0300	oxidoreductase activity
M1M81_11190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1M81_11190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M1M81_11190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1M81_11190	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_11190	COG3321	synthase
M1M81_11195	COG0300	oxidoreductase activity
M1M81_11195	COG3321	synthase
M1M81_11195	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_11195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1M81_11195	COG0318	PFAM AMP-dependent synthetase and ligase
M1M81_11200	COG3321	synthase
M1M81_11200	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_11200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1M81_11200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M1M81_11200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1M81_11205	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_11210	COG0318	PFAM AMP-dependent synthetase and ligase
M1M81_11225	COG2070	2-Nitropropane dioxygenase
M1M81_11225	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M1M81_11230	COG0250	Participates in transcription elongation, termination and antitermination
M1M81_11250	COG0596	Alpha beta hydrolase
M1M81_11265	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
M1M81_11270	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
M1M81_11285	COG0706	membrane insertase activity
M1M81_11290	COG2195	Cleaves the N-terminal amino acid of tripeptides
M1M81_11295	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
M1M81_11300	COG0346	lactoylglutathione lyase activity
M1M81_11315	COG4129	membrane
M1M81_11320	COG1126	abc transporter atp-binding protein
M1M81_11325	COG0765	amino acid transport
M1M81_11330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1M81_11340	COG1597	lipid kinase activity
M1M81_11345	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1M81_11350	COG0022	dehydrogenase e1 component
M1M81_11355	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M1M81_11360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M1M81_11365	COG3426	butyrate kinase activity
M1M81_11370	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M1M81_11375	COG0280	phosphate acetyltransferase
M1M81_11380	COG3829	transcription factor binding
M1M81_11380	COG3290	protein histidine kinase activity
M1M81_11390	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
M1M81_11395	COG2079	MmgE PrpD family protein
M1M81_11400	COG0372	Belongs to the citrate synthase family
M1M81_11405	COG1960	acyl-CoA dehydrogenase activity
M1M81_11410	COG1250	3-hydroxyacyl-CoA dehydrogenase
M1M81_11415	COG0183	Belongs to the thiolase family
M1M81_11420	COG0584	glycerophosphoryl diester phosphodiesterase
M1M81_11425	COG0860	N-Acetylmuramoyl-L-alanine amidase
M1M81_11450	COG1902	pentaerythritol trinitrate reductase activity
M1M81_11465	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M1M81_11470	COG0745	RESPONSE REGULATOR receiver
M1M81_11475	COG0750	zinc metalloprotease
M1M81_11480	COG0497	DNA recombination
M1M81_11490	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
M1M81_11500	COG0142	geranyltranstransferase activity
M1M81_11510	COG1570	exodeoxyribonuclease VII activity
M1M81_11525	COG1302	Protein conserved in bacteria
M1M81_11530	COG0439	Biotin carboxylase
M1M81_11535	COG0511	ligase activity, forming carbon-carbon bonds
M1M81_11575	COG3854	ATPases associated with a variety of cellular activities
M1M81_11590	COG0006	proline dipeptidase activity
M1M81_11600	COG3872	metal-dependent enzyme
M1M81_11610	COG1752	Esterase of the alpha-beta hydrolase superfamily
M1M81_11625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M1M81_11645	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
M1M81_11660	COG1396	sequence-specific DNA binding
M1M81_11670	COG0681	Belongs to the peptidase S26 family
M1M81_11695	COG4940	Competence protein ComGF
M1M81_11705	COG4970	Tfp pilus assembly protein FimT
M1M81_11710	COG4537	Required for transformation and DNA binding
M1M81_11715	COG1459	type II secretion system
M1M81_11720	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
M1M81_11725	COG0598	Magnesium transport protein CorA
M1M81_11730	COG1253	flavin adenine dinucleotide binding
M1M81_11735	COG1366	Belongs to the anti-sigma-factor antagonist family
M1M81_11745	COG1393	Belongs to the ArsC family
M1M81_11755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1M81_11765	COG0011	TIGRFAM Protein of
M1M81_11775	COG2866	Carboxypeptidase
M1M81_11780	COG1940	carbohydrate kinase activity
M1M81_11785	COG4483	Protein conserved in bacteria
M1M81_11790	COG1757	Na H antiporter
M1M81_11800	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
M1M81_11815	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
M1M81_11820	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
M1M81_11825	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
M1M81_11830	COG0581	inorganic phosphate transmembrane transporter activity
M1M81_11835	COG0573	inorganic phosphate transmembrane transporter activity
M1M81_11840	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M1M81_11845	COG0768	penicillin binding
M1M81_11850	COG0477	Major facilitator Superfamily
M1M81_11855	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M1M81_11860	COG2839	Protein conserved in bacteria
M1M81_11865	COG5521	maltodextrose utilization protein MalA
M1M81_11870	COG1388	LysM domain
M1M81_11880	COG4709	membrane
M1M81_11885	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
M1M81_11890	COG0735	belongs to the Fur family
M1M81_11895	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1M81_11910	COG0513	Belongs to the DEAD box helicase family
M1M81_11925	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
M1M81_11930	COG2384	SAM-dependent methyltransferase
M1M81_11935	COG2010	Cytochrome c
M1M81_11940	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
M1M81_11945	COG0358	DNA primase activity
M1M81_11960	COG0517	IMP dehydrogenase activity
M1M81_11965	COG0751	glycine-tRNA ligase activity
M1M81_11985	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
M1M81_11990	COG0295	cytidine deaminase activity
M1M81_11995	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
M1M81_12005	COG1480	7TM receptor with intracellular HD hydrolase
M1M81_12010	COG1702	phosphate starvation-inducible protein PhoH
M1M81_12015	COG0561	phosphatase activity
M1M81_12030	COG4864	UPF0365 protein
M1M81_12035	COG1030	water channel activity
M1M81_12040	COG1610	YqeY-like protein
M1M81_12050	COG1283	sodium-dependent phosphate transmembrane transporter activity
M1M81_12055	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
M1M81_12060	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M1M81_12090	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M1M81_12105	COG0860	N-Acetylmuramoyl-L-alanine amidase
M1M81_12135	COG0658	competence protein
M1M81_12135	COG2333	competence protein COMEC
M1M81_12140	COG2131	deaminase
M1M81_12145	COG1596	polysaccharide export
M1M81_12145	COG1555	photosystem II stabilization
M1M81_12150	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M1M81_12155	COG2226	methyltransferase
M1M81_12160	COG0799	negative regulation of ribosome biogenesis
M1M81_12165	COG1713	HD superfamily hydrolase involved in NAD metabolism
M1M81_12175	COG1534	Rna-binding protein
M1M81_12180	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
M1M81_12185	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
M1M81_12190	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
M1M81_12200	COG2755	lipolytic protein G-D-S-L family
M1M81_12210	COG0398	Pfam SNARE associated Golgi protein
M1M81_12235	COG1794	racemase activity, acting on amino acids and derivatives
M1M81_12255	COG0656	L-ascorbic acid biosynthetic process
M1M81_12285	COG3677	Transposase
M1M81_12325	COG0642	Histidine kinase
M1M81_12325	COG5002	protein histidine kinase activity
M1M81_12330	COG0745	RESPONSE REGULATOR receiver
M1M81_12335	COG2311	Membrane
M1M81_12345	COG0454	-acetyltransferase
M1M81_12350	COG0563	adenylate kinase activity
M1M81_12360	COG2814	Major facilitator Superfamily
M1M81_12365	COG0456	acetyltransferase
M1M81_12370	COG2318	DinB family
M1M81_12380	COG0561	phosphatase activity
M1M81_12385	COG0561	phosphatase activity
M1M81_12395	COG1482	cell wall glycoprotein biosynthetic process
M1M81_12400	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M1M81_12400	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M1M81_12400	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M1M81_12405	COG3711	transcriptional antiterminator
M1M81_12405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M1M81_12415	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
M1M81_12420	COG0583	DNA-binding transcription factor activity
M1M81_12425	COG2814	Major facilitator Superfamily
M1M81_12430	COG2124	cytochrome p450
M1M81_12430	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
M1M81_12435	COG1309	transcriptional regulator
M1M81_12440	COG2226	methyltransferase
M1M81_12455	COG2116	formate transmembrane transporter activity
M1M81_12460	COG5609	conserved protein (DUF2294)
M1M81_12465	COG3383	formate dehydrogenase (NAD+) activity
M1M81_12470	COG2427	Protein of unknown function (DUF1641)
M1M81_12480	COG0626	cystathionine gamma-synthase activity
M1M81_12485	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M1M81_12510	COG0768	penicillin binding
M1M81_12525	COG0826	peptidase U32
M1M81_12530	COG0826	peptidase U32
M1M81_12535	COG4122	O-methyltransferase activity
M1M81_12540	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
M1M81_12565	COG0628	permease
M1M81_12570	COG1126	abc transporter atp-binding protein
M1M81_12575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1M81_12580	COG0765	amino acid transport
M1M81_12585	COG0765	amino acid transport
M1M81_12600	COG3881	PFAM PRC-barrel domain
M1M81_12605	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M1M81_12610	COG0457	Tetratricopeptide repeat
M1M81_12620	COG1104	cysteine desulfurase activity
M1M81_12625	COG1959	2 iron, 2 sulfur cluster binding
M1M81_12630	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
M1M81_12635	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
M1M81_12660	COG0860	N-Acetylmuramoyl-L-alanine amidase
M1M81_12660	COG3103	Sh3 type 3 domain protein
M1M81_12660	COG4991	sh3 domain protein
M1M81_12670	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M1M81_12680	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
M1M81_12680	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
M1M81_12685	COG5416	Lipopolysaccharide assembly protein A domain
M1M81_12690	COG0490	domain, Protein
M1M81_12695	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M1M81_12695	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M1M81_12705	COG2244	polysaccharide biosynthetic process
M1M81_12710	COG2323	membrane
M1M81_12720	COG1862	Preprotein translocase
M1M81_12760	COG1388	LysM domain
M1M81_12770	COG0157	Belongs to the NadC ModD family
M1M81_12775	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
M1M81_12780	COG1104	cysteine desulfurase activity
M1M81_12785	COG1827	regulation of RNA biosynthetic process
M1M81_12790	COG0077	Prephenate dehydratase
M1M81_12805	COG3290	protein histidine kinase activity
M1M81_12810	COG0211	Belongs to the bacterial ribosomal protein bL27 family
M1M81_12815	COG2868	ribosomal protein
M1M81_12825	COG1994	Peptidase M50
M1M81_12830	COG0739	heme binding
M1M81_12835	COG2894	cell division
M1M81_12840	COG0850	regulation of cytokinetic process
M1M81_12845	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
M1M81_12855	COG1077	Cell shape determining protein MreB Mrl
M1M81_12875	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
M1M81_12880	COG0285	dihydrofolate synthase activity
M1M81_12885	COG0525	valine-tRNA ligase activity
M1M81_12895	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M1M81_12900	COG1388	LysM domain
M1M81_12910	COG0113	porphobilinogen synthase activity
M1M81_12915	COG1587	Uroporphyrinogen-III synthase
M1M81_12925	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M1M81_12945	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
M1M81_12950	COG0470	DNA polymerase III
M1M81_12950	COG1067	ATP-dependent peptidase activity
M1M81_12965	COG0457	Tetratricopeptide repeat
M1M81_12965	COG1477	protein flavinylation
M1M81_12980	COG0473	3-isopropylmalate dehydrogenase activity
M1M81_12995	COG0440	acetolactate synthase activity
M1M81_13000	COG0028	Belongs to the TPP enzyme family
M1M81_13025	COG0622	Phosphoesterase
M1M81_13030	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
M1M81_13040	COG5401	PFAM Sporulation and spore germination
M1M81_13050	COG1846	Transcriptional regulator
M1M81_13055	COG2197	response regulator
M1M81_13060	COG0824	Thioesterase
M1M81_13065	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
M1M81_13070	COG1053	succinate dehydrogenase
M1M81_13075	COG2009	succinate dehydrogenase
M1M81_13080	COG1719	4-vinyl reductase, 4VR
M1M81_13085	COG0527	aspartate kinase activity
M1M81_13095	COG3118	belongs to the thioredoxin family
M1M81_13100	COG3534	alpha-L-arabinofuranosidase
M1M81_13105	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
M1M81_13110	COG2086	electron transfer activity
M1M81_13115	COG1024	Enoyl-CoA hydratase
M1M81_13120	COG1309	transcriptional regulator
M1M81_13125	COG0318	PFAM AMP-dependent synthetase and ligase
M1M81_13135	COG3766	membrane
M1M81_13145	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
M1M81_13145	COG1796	DNA polymerase
M1M81_13150	COG1286	toxin biosynthetic process
M1M81_13165	COG0072	phenylalanine-tRNA ligase activity
M1M81_13165	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1M81_13170	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
M1M81_13175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M1M81_13185	COG3835	regulator
M1M81_13190	COG0277	FAD linked oxidase domain protein
M1M81_13195	COG0247	lactate metabolic process
M1M81_13200	COG1966	Carbon starvation protein
M1M81_13205	COG3534	alpha-L-arabinofuranosidase
M1M81_13210	COG0395	ABC-type sugar transport system, permease component
M1M81_13215	COG1175	transmembrane transport
M1M81_13220	COG1653	transport
M1M81_13230	COG0647	UMP catabolic process
M1M81_13235	COG0235	Class ii aldolase
M1M81_13240	COG1069	ribulokinase activity
M1M81_13245	COG2160	L-arabinose isomerase activity
M1M81_13250	COG3507	Belongs to the glycosyl hydrolase 43 family
M1M81_13255	COG1363	Peptidase, m42
M1M81_13265	COG3326	Membrane
M1M81_13280	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
M1M81_13285	COG1346	cytolysis
M1M81_13290	COG1380	Effector of murein hydrolase LrgA
M1M81_13295	COG3279	Response regulator of the LytR AlgR family
M1M81_13300	COG3275	phosphorelay sensor kinase activity
M1M81_13305	COG1011	Hydrolase
M1M81_13320	COG0398	Pfam SNARE associated Golgi protein
M1M81_13325	COG1484	DNA-dependent DNA replication
M1M81_13330	COG3611	Membrane attachment protein
M1M81_13345	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
M1M81_13350	COG1733	regulation of RNA biosynthetic process
M1M81_13355	COG2814	Major facilitator Superfamily
M1M81_13360	COG0656	L-ascorbic acid biosynthetic process
M1M81_13365	COG0237	dephospho-CoA kinase activity
M1M81_13370	COG1971	Probably functions as a manganese efflux pump
M1M81_13375	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
M1M81_13380	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M1M81_13380	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M1M81_13385	COG5002	protein histidine kinase activity
M1M81_13390	COG0745	RESPONSE REGULATOR receiver
M1M81_13400	COG0538	isocitrate dehydrogenase activity
M1M81_13405	COG0372	Belongs to the citrate synthase family
M1M81_13435	COG0628	permease
M1M81_13440	COG3030	protein affecting phage T7 exclusion by the F plasmid
M1M81_13445	COG0469	pyruvate kinase activity
M1M81_13465	COG0281	malic enzyme
M1M81_13470	COG0587	DNA-directed DNA polymerase activity
M1M81_13490	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
M1M81_13500	COG4109	DRTGG domain
M1M81_13510	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_13525	COG0521	Mo-molybdopterin cofactor biosynthetic process
M1M81_13535	COG0827	DNA restriction-modification system
M1M81_13540	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
M1M81_13545	COG3874	Sporulation protein YtfJ
M1M81_13555	COG1714	RDD family
M1M81_13560	COG0616	signal peptide processing
M1M81_13565	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
M1M81_13570	COG1574	metal-dependent hydrolase with the TIM-barrel fold
M1M81_13575	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M1M81_13590	COG1104	cysteine desulfurase activity
M1M81_13595	COG1114	Component of the transport system for branched-chain amino acids
M1M81_13605	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
M1M81_13610	COG1309	transcriptional regulator
M1M81_13615	COG1956	GAF domain-containing protein
M1M81_13620	COG2203	Gaf domain
M1M81_13620	COG2199	diguanylate cyclase activity
M1M81_13630	COG1012	belongs to the aldehyde dehydrogenase family
M1M81_13635	COG4282	regulation of fungal-type cell wall biogenesis
M1M81_13680	COG1017	nitric oxide dioxygenase activity
M1M81_13680	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M1M81_13690	COG0693	protein deglycase activity
M1M81_13705	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
M1M81_13710	COG1378	Sugar-specific transcriptional regulator TrmB
M1M81_13730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M1M81_13735	COG0454	-acetyltransferase
M1M81_13740	COG0517	IMP dehydrogenase activity
M1M81_13745	COG0123	including yeast histone deacetylase and acetoin utilization protein
M1M81_13750	COG1360	Flagellar Motor Protein
M1M81_13755	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
M1M81_13760	COG1609	Transcriptional regulator
M1M81_13765	COG1605	Chorismate mutase
M1M81_13765	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
M1M81_13770	COG3118	belongs to the thioredoxin family
M1M81_13775	COG4980	gas vesicle protein
M1M81_13780	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
M1M81_13790	COG1674	ftsk spoiiie
M1M81_13795	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1M81_13805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M1M81_13815	COG1363	Peptidase, m42
M1M81_13820	COG5584	Small secreted protein
M1M81_13825	COG0281	malic enzyme
M1M81_13830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1M81_13845	COG0510	thiamine kinase activity
M1M81_13850	COG1597	lipid kinase activity
M1M81_13860	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
M1M81_13865	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M1M81_13870	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M1M81_13875	COG2252	PERMEase
M1M81_13880	COG4473	ABC transporter
M1M81_13885	COG1131	(ABC) transporter
M1M81_13890	COG1349	DNA-binding transcription factor activity
M1M81_13895	COG1187	pseudouridine synthase activity
M1M81_13900	COG2244	polysaccharide biosynthetic process
M1M81_13905	COG2081	HI0933 family
M1M81_13910	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1M81_13920	COG1609	Transcriptional regulator
M1M81_13925	COG1653	transport
M1M81_13930	COG1175	transmembrane transport
M1M81_13935	COG0395	ABC-type sugar transport system, permease component
M1M81_13940	COG1486	melibiose metabolic process
M1M81_13950	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M1M81_13965	COG2202	Pas domain
M1M81_13965	COG1366	Belongs to the anti-sigma-factor antagonist family
M1M81_13970	COG2814	Major facilitator Superfamily
M1M81_13975	COG5522	Integral membrane protein (intg_mem_TP0381)
M1M81_13980	COG0577	efflux transmembrane transporter activity
M1M81_13985	COG1136	(ABC) transporter
M1M81_13990	COG2205	protein histidine kinase activity
M1M81_13995	COG0745	RESPONSE REGULATOR receiver
M1M81_14000	COG0577	efflux transmembrane transporter activity
M1M81_14005	COG1136	(ABC) transporter
M1M81_14025	COG1131	(ABC) transporter
M1M81_14030	COG1725	Transcriptional regulator
M1M81_14045	COG1242	4 iron, 4 sulfur cluster binding
M1M81_14050	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
M1M81_14060	COG0584	glycerophosphoryl diester phosphodiesterase
M1M81_14070	COG2267	carboxylic ester hydrolase activity
M1M81_14075	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
M1M81_14080	COG1113	amino acid transport
M1M81_14085	COG0367	asparagine synthase
M1M81_14105	COG1506	peptidase
M1M81_14110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1M81_14115	COG1116	anion transmembrane transporter activity
M1M81_14120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1M81_14125	COG0494	nUDIX hydrolase
M1M81_14130	COG4824	toxin secretion phage lysis holin
M1M81_14135	COG0783	Belongs to the Dps family
M1M81_14160	COG0288	reversible hydration of carbon dioxide
M1M81_14170	COG1271	oxidase subunit
M1M81_14175	COG1294	oxidase, subunit
M1M81_14190	COG4948	Mandelate Racemase Muconate Lactonizing
M1M81_14200	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
M1M81_14205	COG0596	Alpha beta hydrolase
M1M81_14215	COG1169	isochorismate synthase
M1M81_14220	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
M1M81_14225	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
M1M81_14350	COG3859	Proton-coupled thiamine transporter YuaJ
M1M81_14355	COG2268	Band 7 protein
M1M81_14360	COG1585	Membrane protein implicated in regulation of membrane protease activity
M1M81_14365	COG2318	DinB family
M1M81_14375	COG1454	alcohol dehydrogenase
M1M81_14380	COG1012	belongs to the aldehyde dehydrogenase family
M1M81_14385	COG1510	regulation of RNA biosynthetic process
M1M81_14395	COG0569	domain protein
M1M81_14400	COG1705	Flagellar rod assembly protein muramidase FlgJ
M1M81_14405	COG1017	nitric oxide dioxygenase activity
M1M81_14405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M1M81_14430	COG0628	permease
M1M81_14435	COG0673	inositol 2-dehydrogenase activity
M1M81_14440	COG0693	protein deglycase activity
M1M81_14445	COG0840	transmembrane signaling receptor activity
M1M81_14450	COG0840	transmembrane signaling receptor activity
M1M81_14455	COG0840	transmembrane signaling receptor activity
M1M81_14460	COG0840	transmembrane signaling receptor activity
M1M81_14475	COG2070	2-Nitropropane dioxygenase
M1M81_14480	COG0432	Pfam Uncharacterised protein family UPF0047
M1M81_14485	COG0366	Alpha amylase catalytic
M1M81_14490	COG1253	flavin adenine dinucleotide binding
M1M81_14495	COG2738	Putative neutral zinc metallopeptidase
M1M81_14510	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M1M81_14535	COG1335	isochorismatase
M1M81_14540	COG1979	alcohol dehydrogenase
M1M81_14545	COG1979	alcohol dehydrogenase
M1M81_14550	COG2155	Conserved Protein
M1M81_14555	COG1098	S1 RNA binding domain
M1M81_14560	COG0436	Aminotransferase
M1M81_14565	COG1522	sequence-specific DNA binding
M1M81_14570	COG2267	carboxylic ester hydrolase activity
M1M81_14580	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
M1M81_14585	COG2205	protein histidine kinase activity
M1M81_14595	COG5018	Exonuclease
M1M81_14600	COG2814	Major facilitator Superfamily
M1M81_14605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M1M81_14610	COG3011	Protein conserved in bacteria
M1M81_14620	COG3290	protein histidine kinase activity
M1M81_14625	COG4565	transcriptional regulatory protein
M1M81_14630	COG1744	ABC transporter substrate-binding protein PnrA-like
M1M81_14635	COG3845	ABC transporter
M1M81_14640	COG4603	Belongs to the binding-protein-dependent transport system permease family
M1M81_14645	COG1079	Belongs to the binding-protein-dependent transport system permease family
M1M81_14655	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M1M81_14655	COG2111	Na H antiporter
M1M81_14660	COG2111	Na H antiporter
M1M81_14665	COG1006	Multisubunit Na H antiporter MnhC subunit
M1M81_14670	COG0651	ATP synthesis coupled electron transport
M1M81_14675	COG1863	multisubunit Na H antiporter MnhE subunit
M1M81_14680	COG2212	antiporter activity
M1M81_14685	COG1320	monovalent cation:proton antiporter activity
M1M81_14690	COG2050	protein possibly involved in aromatic compounds catabolism
M1M81_14695	COG2197	response regulator
M1M81_14700	COG4585	Histidine kinase
M1M81_14725	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
M1M81_14730	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
M1M81_14735	COG1335	isochorismatase
M1M81_14740	COG5506	Protein of unknown function (DUF1694)
M1M81_14755	COG0628	permease
M1M81_14765	COG1418	mRNA catabolic process
M1M81_14770	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_14780	COG1511	domain protein
M1M81_14785	COG1674	ftsk spoiiie
M1M81_14785	COG0433	COG0433 Predicted ATPase
M1M81_14790	COG4499	WXG100 protein secretion system (Wss), protein YukC
M1M81_14795	COG5417	Belongs to the EsaB family
M1M81_14800	COG4842	Belongs to the WXG100 family
M1M81_14805	COG2508	Transcriptional regulator
M1M81_14805	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
M1M81_14810	COG0686	Belongs to the AlaDH PNT family
M1M81_14815	COG5634	Uncharacterized conserved protein (DUF2278)
M1M81_14820	COG3251	PFAM MbtH domain protein
M1M81_14825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1M81_14830	COG1535	isochorismatase
M1M81_14830	COG3433	isochorismatase activity
M1M81_14835	COG1021	2,3-dihydroxybenzoate-AMP ligase
M1M81_14840	COG1169	isochorismate synthase
M1M81_14845	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_14850	COG2819	hydrolase of the alpha beta superfamily
M1M81_14855	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
M1M81_14860	COG1268	BioY protein
M1M81_14865	COG2056	Na+-H+ antiporter family
M1M81_14875	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
M1M81_14880	COG3584	3D domain protein
M1M81_14895	COG1252	NADH dehydrogenase
M1M81_14925	COG1131	(ABC) transporter
M1M81_14945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1M81_14950	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
M1M81_14955	COG0316	Belongs to the HesB IscA family
M1M81_14965	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M1M81_14975	COG1252	NADH dehydrogenase
M1M81_14980	COG4837	Protein of unknown function (DUF1462)
M1M81_14985	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
M1M81_14990	COG0823	Involved in the tonB-independent uptake of proteins
M1M81_14990	COG1506	peptidase
M1M81_14990	COG4946	Tricorn protease homolog
M1M81_15000	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
M1M81_15005	COG0460	homoserine dehydrogenase
M1M81_15010	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M1M81_15015	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
M1M81_15020	COG0647	UMP catabolic process
M1M81_15025	COG2445	Protein of unknown function DUF86
M1M81_15030	COG4470	Protein conserved in bacteria
M1M81_15040	COG0739	heme binding
M1M81_15050	COG0737	Belongs to the 5'-nucleotidase family
M1M81_15055	COG0730	response to heat
M1M81_15060	COG1801	Protein of unknown function DUF72
M1M81_15075	COG2508	Transcriptional regulator
M1M81_15100	COG2814	Major facilitator Superfamily
M1M81_15105	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
M1M81_15110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M1M81_15115	COG2356	endonuclease I
M1M81_15120	COG3842	ATPase activity
M1M81_15125	COG2188	Transcriptional regulator
M1M81_15130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M1M81_15135	COG0395	ABC-type sugar transport system, permease component
M1M81_15140	COG1175	transmembrane transport
M1M81_15145	COG1653	transport
M1M81_15150	COG2222	sugar isomerase
M1M81_15155	COG0789	Transcriptional regulator
M1M81_15180	COG0322	excinuclease ABC activity
M1M81_15185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1M81_15205	COG3409	Peptidoglycan-binding domain 1 protein
M1M81_15210	COG0719	Fe-S assembly protein
M1M81_15215	COG0822	iron-sulfur transferase activity
M1M81_15220	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
M1M81_15225	COG0719	Fe-S assembly protein
M1M81_15230	COG0396	ATPase activity
M1M81_15240	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M1M81_15245	COG1464	Belongs to the NlpA lipoprotein family
M1M81_15250	COG2011	ABC-type metal ion transport system permease component
M1M81_15255	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M1M81_15265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M1M81_15270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
M1M81_15285	COG1393	Belongs to the ArsC family
M1M81_15290	COG1960	acyl-CoA dehydrogenase activity
M1M81_15295	COG0183	Belongs to the thiolase family
M1M81_15300	COG1024	Enoyl-CoA hydratase
M1M81_15300	COG1250	3-hydroxyacyl-CoA dehydrogenase
M1M81_15320	COG5577	PFAM Coat F domain
M1M81_15325	COG1846	Transcriptional regulator
M1M81_15330	COG0477	Major facilitator Superfamily
M1M81_15335	COG1942	4-Oxalocrotonate Tautomerase
M1M81_15340	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_15345	COG0583	DNA-binding transcription factor activity
M1M81_15355	COG0583	DNA-binding transcription factor activity
M1M81_15375	COG1120	ATPase activity
M1M81_15390	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_15395	COG0783	Belongs to the Dps family
M1M81_15400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M1M81_15405	COG0745	RESPONSE REGULATOR receiver
M1M81_15410	COG2205	protein histidine kinase activity
M1M81_15410	COG2770	Histidine kinase
M1M81_15420	COG1309	transcriptional regulator
M1M81_15425	COG0114	fumarate hydratase activity
M1M81_15435	COG0697	spore germination
M1M81_15440	COG0814	amino acid
M1M81_15450	COG2197	response regulator
M1M81_15455	COG4585	Histidine kinase
M1M81_15460	COG4758	membrane
M1M81_15465	COG3595	metallopeptidase activity
M1M81_15470	COG1842	Phage shock protein A
M1M81_15475	COG4758	membrane
M1M81_15480	COG2814	Major facilitator Superfamily
M1M81_15485	COG2096	Adenosyltransferase
M1M81_15490	COG1120	ATPase activity
M1M81_15495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1M81_15500	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M1M81_15505	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_15510	COG3386	PFAM SMP-30 Gluconolaconase
M1M81_15515	COG2205	protein histidine kinase activity
M1M81_15520	COG0745	RESPONSE REGULATOR receiver
M1M81_15530	COG1191	sigma factor activity
M1M81_15540	COG2140	Oxalate decarboxylase
M1M81_15550	COG1120	ATPase activity
M1M81_15555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1M81_15560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1M81_15565	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M1M81_15570	COG0531	amino acid
M1M81_15580	COG1988	membrane-bound metal-dependent
M1M81_15585	COG1368	sulfuric ester hydrolase activity
M1M81_15590	COG1910	domain protein
M1M81_15595	COG0725	ABC transporter, periplasmic molybdate-binding protein
M1M81_15600	COG4149	molybdate abc transporter
M1M81_15605	COG2197	response regulator
M1M81_15610	COG3850	Histidine kinase
M1M81_15615	COG1131	(ABC) transporter
M1M81_15625	COG0842	Transport permease protein
M1M81_15630	COG0656	L-ascorbic acid biosynthetic process
M1M81_15650	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
M1M81_15655	COG3973	AAA domain
M1M81_15660	COG2860	membrane
M1M81_15670	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
M1M81_15675	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M1M81_15680	COG2217	Heavy metal translocating P-type atpase
M1M81_15685	COG2217	Heavy metal translocating P-type atpase
M1M81_15690	COG2608	mercury ion transmembrane transporter activity
M1M81_15695	COG1937	Protein conserved in bacteria
M1M81_15700	COG0673	inositol 2-dehydrogenase activity
M1M81_15710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1M81_15715	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
M1M81_15720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1M81_15725	COG1126	abc transporter atp-binding protein
M1M81_15730	COG0765	amino acid transport
M1M81_15735	COG0765	amino acid transport
M1M81_15740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1M81_15745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1M81_15750	COG0454	-acetyltransferase
M1M81_15755	COG0583	DNA-binding transcription factor activity
M1M81_15760	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_15805	COG0557	exoribonuclease II activity
M1M81_15810	COG1647	Serine aminopeptidase, S33
M1M81_15815	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
M1M81_15820	COG1476	TRANSCRIPTIONal
M1M81_15825	COG1396	sequence-specific DNA binding
M1M81_15830	COG1396	sequence-specific DNA binding
M1M81_15835	COG1733	regulation of RNA biosynthetic process
M1M81_15860	COG1131	(ABC) transporter
M1M81_15865	COG1174	glycine betaine transport
M1M81_15870	COG1732	Glycine betaine
M1M81_15875	COG1174	glycine betaine transport
M1M81_15880	COG0517	IMP dehydrogenase activity
M1M81_15880	COG1125	glycine betaine transport
M1M81_15885	COG1510	regulation of RNA biosynthetic process
M1M81_15890	COG1174	glycine betaine transport
M1M81_15895	COG1732	Glycine betaine
M1M81_15900	COG1174	glycine betaine transport
M1M81_15905	COG0517	IMP dehydrogenase activity
M1M81_15905	COG1125	glycine betaine transport
M1M81_15910	COG1510	regulation of RNA biosynthetic process
M1M81_15915	COG2095	MarC family integral membrane protein
M1M81_15920	COG3064	Membrane
M1M81_15925	COG4640	response to antibiotic
M1M81_15930	COG0456	acetyltransferase
M1M81_15945	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M1M81_15965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M1M81_15970	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
M1M81_15980	COG2234	aminopeptidase activity
M1M81_16000	COG0126	phosphoglycerate kinase activity
M1M81_16005	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
M1M81_16010	COG2390	Transcriptional regulator
M1M81_16015	COG2814	Major facilitator Superfamily
M1M81_16020	COG1609	Transcriptional regulator
M1M81_16025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1M81_16035	COG0583	DNA-binding transcription factor activity
M1M81_16040	COG0697	spore germination
M1M81_16045	COG1113	amino acid transport
M1M81_16050	COG1609	Transcriptional regulator
M1M81_16060	COG0561	phosphatase activity
M1M81_16065	COG1737	Transcriptional regulator
M1M81_16070	COG1070	Carbohydrate kinase
M1M81_16110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1M81_16115	COG2186	Transcriptional regulator
M1M81_16120	COG1620	l-lactate permease
M1M81_16125	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
M1M81_16135	COG5039	Polysaccharide pyruvyl transferase
M1M81_16140	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
M1M81_16145	COG0110	maltose O-acetyltransferase activity
M1M81_16150	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
M1M81_16155	COG2244	polysaccharide biosynthetic process
M1M81_16160	COG1216	Glycosyl transferase, family 2
M1M81_16165	COG5039	Polysaccharide pyruvyl transferase
M1M81_16170	COG1216	Glycosyl transferase, family 2
M1M81_16180	COG0438	transferase activity, transferring glycosyl groups
M1M81_16185	COG1215	transferase activity, transferring glycosyl groups
M1M81_16190	COG0438	transferase activity, transferring glycosyl groups
M1M81_16195	COG1086	Polysaccharide biosynthesis protein
M1M81_16200	COG0489	protein tyrosine kinase activity
M1M81_16205	COG3944	biosynthesis protein
M1M81_16210	COG1396	sequence-specific DNA binding
M1M81_16215	COG2272	Belongs to the type-B carboxylesterase lipase family
M1M81_16220	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M1M81_16225	COG2364	Membrane
M1M81_16230	COG0456	acetyltransferase
M1M81_16235	COG3479	Phenolic acid decarboxylase
M1M81_16290	COG2223	nitrite transmembrane transporter activity
M1M81_16295	COG1609	Transcriptional regulator
M1M81_16305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M1M81_16310	COG0366	Alpha amylase catalytic
M1M81_16315	COG1554	hydrolase, family 65, central catalytic
M1M81_16320	COG5521	maltodextrose utilization protein MalA
M1M81_16325	COG3833	ABC-type maltose transport systems, permease component
M1M81_16330	COG1175	transmembrane transport
M1M81_16335	COG2182	Extracellular solute-binding protein
M1M81_16340	COG0366	Alpha amylase catalytic
M1M81_16345	COG1609	Transcriptional regulator
M1M81_16350	COG1611	Belongs to the LOG family
M1M81_16355	COG1694	Mazg nucleotide pyrophosphohydrolase
M1M81_16360	COG0659	secondary active sulfate transmembrane transporter activity
M1M81_16365	COG0288	reversible hydration of carbon dioxide
M1M81_16370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M1M81_16375	COG4290	ribonuclease
M1M81_16380	COG2162	N-hydroxyarylamine O-acetyltransferase activity
M1M81_16385	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M1M81_16395	COG0391	Required for morphogenesis under gluconeogenic growth conditions
M1M81_16405	COG1051	belongs to the nudix hydrolase family
M1M81_16410	COG0492	ferredoxin-NADP+ reductase activity
M1M81_16415	COG0791	NLP P60 protein
M1M81_16415	COG3883	PFAM NLP P60 protein
M1M81_16420	COG0457	Tetratricopeptide repeat
M1M81_16425	COG5002	protein histidine kinase activity
M1M81_16430	COG0745	RESPONSE REGULATOR receiver
M1M81_16435	COG1132	(ABC) transporter
M1M81_16440	COG0140	phosphoribosyl-ATP diphosphatase activity
M1M81_16440	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
M1M81_16465	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
M1M81_16480	COG4990	cell redox homeostasis
M1M81_16485	COG0110	maltose O-acetyltransferase activity
M1M81_16505	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
M1M81_16515	COG2188	Transcriptional regulator
M1M81_16520	COG1309	transcriptional regulator
M1M81_16525	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
M1M81_16530	COG1950	PFAM Membrane protein of
M1M81_16535	COG1983	PspC domain protein
M1M81_16540	COG3595	metallopeptidase activity
M1M81_16555	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M1M81_16565	COG4897	Protein conserved in bacteria
M1M81_16570	COG3848	Pyruvate phosphate dikinase
M1M81_16570	COG0574	Belongs to the PEP-utilizing enzyme family
M1M81_16575	COG1309	transcriptional regulator
M1M81_16580	COG2814	Major facilitator Superfamily
M1M81_16595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M1M81_16605	COG0793	Belongs to the peptidase S41A family
M1M81_16605	COG3409	Peptidoglycan-binding domain 1 protein
M1M81_16610	COG3420	alginic acid biosynthetic process
M1M81_16615	COG2177	Part of the ABC transporter FtsEX involved in
M1M81_16620	COG2884	Cell division ATP-binding protein ftsE
M1M81_16625	COG2010	Cytochrome c
M1M81_16630	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1M81_16645	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
M1M81_16660	COG1516	flagellar protein fliS
M1M81_16665	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
M1M81_16670	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
M1M81_16690	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
M1M81_16695	COG1256	bacterial-type flagellum assembly
M1M81_16695	COG4786	Flagellar basal body rod
M1M81_16700	COG3418	PFAM FlgN family protein
M1M81_16705	COG2747	anti-sigma28 factor FlgM
M1M81_16715	COG1040	competence protein
M1M81_16725	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
M1M81_16730	COG1307	EDD domain protein, DegV family
M1M81_16735	COG2197	response regulator
M1M81_16740	COG4585	Histidine kinase
M1M81_16745	COG1739	Uncharacterized protein family UPF0029
M1M81_16750	COG1316	TRANSCRIPTIONal
M1M81_16755	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
M1M81_16760	COG0438	transferase activity, transferring glycosyl groups
M1M81_16765	COG1215	transferase activity, transferring glycosyl groups
M1M81_16770	COG3206	protein involved in exopolysaccharide biosynthesis
M1M81_16775	COG3307	-O-antigen
M1M81_16780	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
M1M81_16785	COG0438	transferase activity, transferring glycosyl groups
M1M81_16785	COG0297	glycogen (starch) synthase activity
M1M81_16790	COG2244	polysaccharide biosynthetic process
M1M81_16800	COG2247	cell wall binding repeat
M1M81_16800	COG0860	N-Acetylmuramoyl-L-alanine amidase
M1M81_16805	COG2247	cell wall binding repeat
M1M81_16805	COG2385	sporulation resulting in formation of a cellular spore
M1M81_16815	COG1316	TRANSCRIPTIONal
M1M81_16820	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
M1M81_16825	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M1M81_16830	COG1134	teichoic acid transport
M1M81_16835	COG1682	transport, permease protein
M1M81_16840	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
M1M81_16850	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
M1M81_16855	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
M1M81_16860	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
M1M81_16865	COG4193	domain, Protein
M1M81_16870	COG1482	cell wall glycoprotein biosynthetic process
M1M81_16875	COG0697	spore germination
M1M81_16880	COG0814	amino acid
M1M81_16890	COG1215	transferase activity, transferring glycosyl groups
M1M81_16895	COG2814	Major facilitator Superfamily
M1M81_16900	COG1316	TRANSCRIPTIONal
M1M81_16905	COG0561	phosphatase activity
M1M81_16910	COG2433	Pfam Transposase IS66
M1M81_16915	COG0791	NLP P60 protein
M1M81_16925	COG2843	Capsule synthesis protein
M1M81_16935	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
M1M81_16940	COG0697	spore germination
M1M81_16945	COG0814	amino acid
M1M81_16955	COG1609	Transcriptional regulator
M1M81_16960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M1M81_16970	COG1129	ABC transporter
M1M81_16975	COG1172	Belongs to the binding-protein-dependent transport system permease family
M1M81_16980	COG1879	ABC-type sugar transport system periplasmic component
M1M81_16985	COG3103	Sh3 type 3 domain protein
M1M81_16990	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1M81_16995	COG3527	Alpha-acetolactate decarboxylase
M1M81_17000	COG0028	Belongs to the TPP enzyme family
M1M81_17005	COG0583	DNA-binding transcription factor activity
M1M81_17010	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
M1M81_17025	COG5337	Spore coat protein CotH
M1M81_17035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1M81_17045	COG0405	Gamma-glutamyltransferase
M1M81_17050	COG1522	sequence-specific DNA binding
M1M81_17055	COG2059	Chromate
M1M81_17060	COG2059	Chromate
M1M81_17070	COG0655	NAD(P)H dehydrogenase (quinone) activity
M1M81_17075	COG0583	DNA-binding transcription factor activity
M1M81_17105	COG5444	nuclease activity
M1M81_17120	COG3878	Protein conserved in bacteria
M1M81_17125	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
M1M81_17130	COG4464	protein tyrosine phosphatase activity
M1M81_17135	COG0489	protein tyrosine kinase activity
M1M81_17140	COG3944	biosynthesis protein
M1M81_17150	COG4715	Zinc finger, swim domain protein
M1M81_17155	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
M1M81_17160	COG0561	phosphatase activity
M1M81_17165	COG1349	DNA-binding transcription factor activity
M1M81_17170	COG0629	single-stranded DNA binding
M1M81_17195	COG0457	Tetratricopeptide repeat
M1M81_17200	COG4786	Flagellar basal body rod
M1M81_17205	COG4786	Flagellar basal body rod
M1M81_17210	COG1077	Cell shape determining protein MreB Mrl
M1M81_17215	COG1609	Transcriptional regulator
M1M81_17220	COG1846	Transcriptional regulator
M1M81_17225	COG2814	Major facilitator Superfamily
M1M81_17230	COG1953	Uracil, thiamine, allantoin
M1M81_17235	COG0477	Major facilitator Superfamily
M1M81_17240	COG1335	isochorismatase
M1M81_17245	COG0004	ammonium transporteR
M1M81_17250	COG0347	Belongs to the P(II) protein family
M1M81_17255	COG0772	Belongs to the SEDS family
M1M81_17260	COG0671	phosphoesterase, PA-phosphatase related
M1M81_17270	COG0739	heme binding
M1M81_17275	COG1247	-acetyltransferase
M1M81_17290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M1M81_17300	COG0726	polysaccharide deacetylase
M1M81_17310	COG1959	2 iron, 2 sulfur cluster binding
M1M81_17325	COG0831	urea catabolic process
M1M81_17330	COG3237	CsbD-like
M1M81_17335	COG1994	Peptidase M50
M1M81_17340	COG0457	Tetratricopeptide repeat
M1M81_17350	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
M1M81_17360	COG2304	oxidoreductase activity
M1M81_17365	COG2304	oxidoreductase activity
M1M81_17370	COG2385	sporulation resulting in formation of a cellular spore
M1M81_17375	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
M1M81_17385	COG4836	Membrane
M1M81_17455	COG0698	ribose 5-phosphate isomerase
M1M81_17460	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
M1M81_17470	COG0009	L-threonylcarbamoyladenylate synthase
M1M81_17475	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
M1M81_17495	COG2890	protein-(glutamine-N5) methyltransferase activity
M1M81_17500	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
M1M81_17505	COG0346	lactoylglutathione lyase activity
M1M81_17510	COG0789	Transcriptional regulator
M1M81_17515	COG0679	Auxin Efflux Carrier
M1M81_17520	COG0281	malic enzyme
M1M81_17535	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
M1M81_17545	COG1494	fructose-1,6-bisphosphatase
M1M81_17550	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
M1M81_17560	COG0191	fructose-bisphosphate aldolase activity
M1M81_17565	COG2204	response regulator
M1M81_17570	COG4821	SIS domain
M1M81_17585	COG0247	lactate metabolic process
M1M81_17585	COG2181	nitrate reductase activity
M1M81_17590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M1M81_17605	COG1132	(ABC) transporter
M1M81_17610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M1M81_17620	COG2181	nitrate reductase activity
M1M81_17625	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
M1M81_17630	COG1140	nitrate reductase beta subunit
M1M81_17635	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
M1M81_17640	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M1M81_17650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M1M81_17655	COG2223	nitrite transmembrane transporter activity
M1M81_17665	COG4506	Protein conserved in bacteria
M1M81_17675	COG3391	amine dehydrogenase activity
M1M81_17680	COG3391	amine dehydrogenase activity
M1M81_17685	COG0457	Tetratricopeptide repeat
M1M81_17695	COG0010	Belongs to the arginase family
M1M81_17700	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
M1M81_17705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M1M81_17720	COG1994	Peptidase M50
M1M81_17725	COG1942	4-Oxalocrotonate Tautomerase
M1M81_17730	COG1846	Transcriptional regulator
M1M81_17735	COG0531	amino acid
M1M81_17740	COG3465	dGTPase activity
M1M81_17745	COG1078	dGTPase activity
M1M81_17760	COG1695	Transcriptional regulator
M1M81_17770	COG1131	(ABC) transporter
M1M81_17775	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
M1M81_17805	COG0583	DNA-binding transcription factor activity
M1M81_17810	COG2855	membrane
M1M81_17815	COG0280	phosphate acetyltransferase
M1M81_17825	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_17830	COG0436	Aminotransferase
M1M81_17860	COG2814	Major facilitator Superfamily
M1M81_17865	COG2814	Major facilitator Superfamily
M1M81_17870	COG0833	amino acid
M1M81_17875	COG4187	Peptidase family M20/M25/M40
M1M81_17880	COG1012	belongs to the aldehyde dehydrogenase family
M1M81_17885	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M1M81_17890	COG2205	protein histidine kinase activity
M1M81_17895	COG0745	RESPONSE REGULATOR receiver
M1M81_17910	COG1131	(ABC) transporter
M1M81_17915	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
M1M81_17920	COG1091	dTDP-4-dehydrorhamnose reductase activity
M1M81_17925	COG1088	dTDP-glucose 4,6-dehydratase activity
M1M81_17930	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
M1M81_17935	COG3980	spore coat polysaccharide biosynthesis protein
M1M81_17940	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
M1M81_17945	COG2089	acid synthase
M1M81_17950	COG0456	acetyltransferase
M1M81_17955	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
M1M81_17960	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
M1M81_17965	COG0463	Glycosyl transferase, family 2
M1M81_17975	COG2363	Small membrane protein
M1M81_17980	COG2233	PERMEase
M1M81_17995	COG1216	Glycosyl transferase, family 2
M1M81_18010	COG1695	Transcriptional regulator
M1M81_18015	COG0351	phosphomethylpyrimidine kinase
M1M81_18025	COG1621	beta-fructofuranosidase activity
M1M81_18030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M1M81_18030	COG1263	PTS System
M1M81_18035	COG3711	transcriptional antiterminator
M1M81_18045	COG1404	Belongs to the peptidase S8 family
M1M81_18050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1M81_18055	COG0778	Nitroreductase
M1M81_18060	COG0772	Belongs to the SEDS family
M1M81_18065	COG0454	-acetyltransferase
M1M81_18085	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
M1M81_18090	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
M1M81_18095	COG2261	transglycosylase associated protein
M1M81_18100	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
M1M81_18105	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
M1M81_18110	COG2246	polysaccharide biosynthetic process
M1M81_18115	COG1309	transcriptional regulator
M1M81_18135	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
M1M81_18140	COG2837	iron assimilation
M1M81_18160	COG0583	DNA-binding transcription factor activity
M1M81_18170	COG1346	cytolysis
M1M81_18175	COG4895	conserved protein (DUF2196)
M1M81_18180	COG0789	Transcriptional regulator
M1M81_18185	COG5504	Zn-dependent protease
M1M81_18190	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
M1M81_18195	COG0346	lactoylglutathione lyase activity
M1M81_18200	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M1M81_18205	COG1404	Belongs to the peptidase S8 family
M1M81_18210	COG1442	glycosyl transferase family 8
M1M81_18215	COG2357	RelA SpoT domain protein
M1M81_18220	COG1575	Belongs to the MenA family. Type 1 subfamily
M1M81_18235	COG1696	Membrane protein involved in D-alanine export
M1M81_18245	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
M1M81_18250	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M1M81_18255	COG1486	melibiose metabolic process
M1M81_18260	COG1447	Phosphotransferase system cellobiose-specific component IIA
M1M81_18265	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M1M81_18270	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M1M81_18275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M1M81_18275	COG3711	transcriptional antiterminator
M1M81_18285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1M81_18290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1M81_18300	COG0640	Transcriptional regulator
M1M81_18305	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
M1M81_18310	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M1M81_18315	COG1447	Phosphotransferase system cellobiose-specific component IIA
M1M81_18320	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M1M81_18325	COG2723	6-phospho-beta-galactosidase activity
M1M81_18335	COG1482	cell wall glycoprotein biosynthetic process
M1M81_18345	COG0753	catalase activity
M1M81_18350	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
M1M81_18355	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
M1M81_18375	COG3279	Response regulator of the LytR AlgR family
M1M81_18395	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
M1M81_18400	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
M1M81_18405	COG4988	ABC transporter
M1M81_18410	COG1294	oxidase, subunit
M1M81_18415	COG1271	oxidase subunit
M1M81_18420	COG3493	citrate carrier protein
M1M81_18425	COG0726	polysaccharide deacetylase
M1M81_18430	COG3842	ATPase activity
M1M81_18435	COG2508	Transcriptional regulator
M1M81_18440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1M81_18450	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M1M81_18465	COG4894	glucomannan catabolic process
M1M81_18470	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
M1M81_18475	COG0500	methyltransferase
M1M81_18480	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M1M81_18495	COG0753	catalase activity
M1M81_18495	COG0693	protein deglycase activity
M1M81_18500	COG2851	Citrate transporter
M1M81_18505	COG2273	Hydrolase Family 16
M1M81_18515	COG2270	Major facilitator Superfamily
M1M81_18520	COG0513	Belongs to the DEAD box helicase family
M1M81_18530	COG0697	spore germination
M1M81_18535	COG0589	response to stress
M1M81_18595	COG3507	Belongs to the glycosyl hydrolase 43 family
M1M81_18620	COG0010	Belongs to the arginase family
M1M81_18625	COG0833	amino acid
M1M81_18630	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
M1M81_18635	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M1M81_18645	COG2390	Transcriptional regulator
M1M81_18650	COG0561	phosphatase activity
M1M81_18680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M1M81_18685	COG5294	Protein conserved in bacteria
M1M81_18690	COG0577	efflux transmembrane transporter activity
M1M81_18695	COG1136	(ABC) transporter
M1M81_18700	COG2205	protein histidine kinase activity
M1M81_18705	COG0745	RESPONSE REGULATOR receiver
M1M81_18710	COG2205	protein histidine kinase activity
M1M81_18715	COG0745	RESPONSE REGULATOR receiver
M1M81_18745	COG1082	Xylose isomerase domain protein TIM barrel
M1M81_18755	COG2814	Major facilitator Superfamily
M1M81_18785	COG1349	DNA-binding transcription factor activity
M1M81_18790	COG0667	Aldo Keto reductase
M1M81_18795	COG2814	Major facilitator Superfamily
M1M81_18810	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_18815	COG2197	response regulator
M1M81_18820	COG4585	Histidine kinase
M1M81_18825	COG3239	Fatty acid desaturase
M1M81_18830	COG1309	transcriptional regulator
M1M81_18835	COG1012	belongs to the aldehyde dehydrogenase family
M1M81_18840	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
M1M81_18850	COG0640	Transcriptional regulator
M1M81_18855	COG2814	Major facilitator Superfamily
M1M81_18860	COG1714	RDD family
M1M81_18870	COG0450	alkyl hydroperoxide reductase
M1M81_18875	COG3634	alkyl hydroperoxide reductase activity
M1M81_18880	COG3177	Filamentation induced by cAMP protein fic
M1M81_18885	COG1113	amino acid transport
M1M81_18895	COG2080	2 iron, 2 sulfur cluster binding
M1M81_18910	COG2068	MobA-Related Protein
M1M81_18915	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
M1M81_18970	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
M1M81_18975	COG0667	Aldo Keto reductase
M1M81_18980	COG0456	acetyltransferase
M1M81_18985	COG0457	Tetratricopeptide repeat
M1M81_18990	COG0010	Belongs to the arginase family
M1M81_18995	COG0833	amino acid
M1M81_19000	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M1M81_19005	COG5658	integral membrane protein
M1M81_19010	COG0640	Transcriptional regulator
M1M81_19015	COG3829	transcription factor binding
M1M81_19025	COG0488	(ABC) transporter
M1M81_19040	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M1M81_19045	COG5002	protein histidine kinase activity
M1M81_19045	COG3850	Histidine kinase
M1M81_19055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M1M81_19060	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
M1M81_19065	COG4853	Protein conserved in bacteria
M1M81_19070	COG4863	YycH protein
M1M81_19075	COG5002	protein histidine kinase activity
M1M81_19080	COG0745	RESPONSE REGULATOR receiver
M1M81_19110	COG0346	lactoylglutathione lyase activity
M1M81_19115	COG0305	Participates in initiation and elongation during chromosome replication
M1M81_19130	COG3093	addiction module antidote protein HigA
M1M81_19135	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
M1M81_19140	COG0297	glycogen (starch) synthase activity
M1M81_19150	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
M1M81_19155	COG0438	transferase activity, transferring glycosyl groups
M1M81_19175	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
M1M81_19180	COG4241	membrane
M1M81_19190	COG5577	PFAM Coat F domain
M1M81_19195	COG1733	regulation of RNA biosynthetic process
M1M81_19205	COG0697	spore germination
M1M81_19210	COG1621	beta-fructofuranosidase activity
M1M81_19215	COG1621	beta-fructofuranosidase activity
M1M81_19225	COG2318	DinB family
M1M81_19230	COG2211	Major facilitator Superfamily
M1M81_19240	COG0778	Nitroreductase
M1M81_19250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1M81_19255	COG1846	Transcriptional regulator
M1M81_19260	COG2153	protein acetylation
M1M81_19270	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M1M81_19275	COG0583	DNA-binding transcription factor activity
M1M81_19280	COG1028	Short-chain dehydrogenase reductase Sdr
M1M81_19285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1M81_19290	COG0697	spore germination
M1M81_19320	COG1331	Highly conserved protein containing a thioredoxin domain
M1M81_19325	COG1266	CAAX protease self-immunity
M1M81_19330	COG0477	Major facilitator Superfamily
M1M81_19330	COG2814	Major facilitator Superfamily
M1M81_19335	COG0346	lactoylglutathione lyase activity
M1M81_19340	COG1609	Transcriptional regulator
M1M81_19345	COG0708	Exodeoxyribonuclease III
M1M81_19350	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M1M81_19355	COG2169	Transcriptional regulator
M1M81_19365	COG0629	single-stranded DNA binding
M1M81_19375	COG0012	GTP binding
M1M81_19380	COG0243	molybdopterin cofactor binding
M1M81_19385	COG4481	Protein conserved in bacteria
M1M81_19390	COG3949	Membrane
M1M81_19405	COG1475	DNA binding
M1M81_19410	COG1192	Involved in chromosome partitioning
M1M81_19435	COG1847	R3H domain protein
M1M81_19440	COG0706	membrane insertase activity