locus-tag class description BAALB65_00005 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) BAALB65_00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BAALB65_00015 ENOG410848D S4 domain protein YaaA BAALB65_00020 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) BAALB65_00030 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BAALB65_00035 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BAALB65_00070 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BAALB65_00080 ENOG4105CD9 Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity) BAALB65_00085 ENOG4108UHX Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity) BAALB65_00090 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) BAALB65_00095 ENOG4105BZW Glycerate kinase BAALB65_00105 ENOG4105ZMH deoxynucleoside kinase BAALB65_00115 ENOG4105VRS hydrolase family 18 BAALB65_00120 ENOG4105GTG Isochorismatase BAALB65_00125 ENOG4108Z6B deaminase BAALB65_00135 ENOG4105C6E dna polymerase iii BAALB65_00140 ENOG410816I Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) BAALB65_00145 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) BAALB65_00155 ENOG41067KS pro-sigma K processing BAALB65_00195 ENOG4105CDW Resistance protein BAALB65_00200 ENOG4105CXN decarboxylase BAALB65_00205 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) BAALB65_00210 ENOG4105X0R protein from nitrogen regulatory protein P-II BAALB65_00215 ENOG4105XVJ Protein of unknown function (DUF327) BAALB65_00220 ENOG4105FA2 dna polymerase iii BAALB65_00225 ENOG4105MA4 psp1 domain protein BAALB65_00235 ENOG41060K3 Methyltransferase BAALB65_00240 ENOG4105VC4 domain protein BAALB65_00245 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BAALB65_00250 ENOG4105KRN Transcriptional regulator, abrb family BAALB65_00255 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BAALB65_00260 ENOG4105F8V Hydrolase, tatD family BAALB65_00265 ENOG41069ER domain protein BAALB65_00275 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) BAALB65_00280 ENOG4105XFA sporulation peptidase YabG BAALB65_00285 ENOG4105W42 Veg protein BAALB65_00290 ENOG4105XEW small acid-soluble spore protein BAALB65_00295 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) BAALB65_00300 ENOG4105DFT pur operon repressor BAALB65_00305 ENOG4105KME endoribonuclease L-psp BAALB65_00310 ENOG4105K4W Could be involved in septation (By similarity) BAALB65_00315 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) BAALB65_00320 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BAALB65_00325 ENOG4105KW6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) BAALB65_00340 ENOG4108JA2 transcriptioN-repair coupling factor BAALB65_00345 ENOG4108M14 stage v sporulation protein t BAALB65_00355 ENOG4108IY2 MazG family BAALB65_00360 ENOG41082I2 s4 domain protein BAALB65_00365 ENOG4105VYY sporulation protein yabp BAALB65_00380 ENOG41060GV RNA binding s1 domain protein BAALB65_00410 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BAALB65_00415 ENOG4108UGV hypoxanthine phosphoribosyltransferase BAALB65_00420 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BAALB65_00425 ENOG4105CGM Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity) BAALB65_00430 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) BAALB65_00435 ENOG4107U48 ppic-type peptidyL-prolyl cis-trans isomerase BAALB65_00440 ENOG4105C6T cysteine synthase BAALB65_00445 ENOG4105CRQ synthase (Component I) BAALB65_00450 ENOG4105DDQ anthranilate synthase BAALB65_00455 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BAALB65_00460 ENOG4105EEI dihydropteroate synthase BAALB65_00465 ENOG4105KRF dihydroneopterin aldolase BAALB65_00470 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BAALB65_00480 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BAALB65_00485 ENOG4105CRK lysyL-tRNA synthetase BAALB65_00570 ENOG4108Z0C Uvrb UvrC protein BAALB65_00575 ENOG41066A3 ATP guanido phosphotransferase BAALB65_00585 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BAALB65_00590 ENOG4105E59 Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity) BAALB65_00595 ENOG4105CTP PilT protein domain protein BAALB65_00600 ENOG4108QHG Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) BAALB65_00605 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) BAALB65_00610 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) BAALB65_00615 ENOG4105D7W serine acetyltransferase BAALB65_00625 ENOG4105KEB Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) BAALB65_00630 ENOG4105C2N RNA methyltransferase TrmH family group 3 BAALB65_00635 ENOG4105M0M Tetracycline resistance protein BAALB65_00655 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BAALB65_00660 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) BAALB65_00670 ENOG4108VZM 50s ribosomal protein L10 BAALB65_00675 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) BAALB65_00680 ENOG4107Y49 methyltransferase BAALB65_00685 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BAALB65_00690 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BAALB65_00695 ENOG4105XPM ribosomal protein BAALB65_00700 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) BAALB65_00705 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) BAALB65_00710 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) BAALB65_00715 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) BAALB65_00720 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BAALB65_00725 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) BAALB65_00730 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) BAALB65_00735 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) BAALB65_00740 ENOG41080UE One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) BAALB65_00745 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity BAALB65_00750 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) BAALB65_00755 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) BAALB65_00760 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) BAALB65_00765 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) BAALB65_00770 ENOG41082SA 50s ribosomal protein l29 BAALB65_00775 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal BAALB65_00790 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits BAALB65_00800 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) BAALB65_00805 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BAALB65_00810 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) BAALB65_00815 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) BAALB65_00820 ENOG4105VPB 50S ribosomal protein L30 BAALB65_00825 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) BAALB65_00830 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BAALB65_00835 ENOG4105CC8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) BAALB65_00840 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BAALB65_00850 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) BAALB65_00860 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits BAALB65_00865 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) BAALB65_00870 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BAALB65_00875 ENOG4108ZT0 50S ribosomal protein l17 BAALB65_00880 ENOG4108JJB ABC transporter BAALB65_00885 ENOG4108JJB ABC transporter BAALB65_00890 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BAALB65_00895 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BAALB65_00900 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) BAALB65_00905 ENOG4108UJD 30S ribosomal protein S9 BAALB65_00910 ENOG4108I0C methyltransferase BAALB65_00930 ENOG4105D1F ATP-binding protein BAALB65_00945 ENOG4108NMV polysaccharide deacetylase BAALB65_00975 ENOG4107T65 Integrase BAALB65_00980 ENOG410635T phage-like element pbsx protein BAALB65_00990 ENOG41067QW Transcriptional regulator BAALB65_01055 ENOG4105CDU Replicative dna helicase BAALB65_01065 ENOG4105QBX endodeoxyribonuclease RusA BAALB65_01160 ENOG4105IG6 Phage terminase, large subunit BAALB65_01165 ENOG4108MDF Phage Portal Protein BAALB65_01170 ENOG4106CGH Phage Mu protein F like protein BAALB65_01205 ENOG41060SN BAALB65_01220 ENOG4105PQS phage protein BAALB65_01225 ENOG4105FR7 XkdM protein, phage-like element PBSX BAALB65_01235 ENOG4105MTC XkdN-like protein BAALB65_01240 ENOG4108FKH Transglycosylase SLT domain BAALB65_01245 ENOG4108WZM domain protein BAALB65_01250 ENOG4105X7F BAALB65_01260 ENOG4105MFU Protein of unknown function (DUF2634) BAALB65_01265 ENOG41066EA baseplate J family protein BAALB65_01270 ENOG410906S phage-like element pbsx protein xkdt BAALB65_01310 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BAALB65_01390 ENOG4108JPW Aminotransferase BAALB65_01405 ENOG4105CHH sulfate transporter BAALB65_01415 ENOG4108SA1 esterase BAALB65_01435 ENOG410874W AraC family transcriptional regulator BAALB65_01440 ENOG4105EHZ conserved protein UCP016719 BAALB65_01445 ENOG4105D17 glycoside hydrolase, family 3 domain protein BAALB65_01460 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate BAALB65_01470 ENOG4105EWC Purine nucleoside phosphorylase BAALB65_01500 ENOG4105EMN RNA polymerase sigma factor BAALB65_01510 ENOG4105C8B TIGR00159 family BAALB65_01515 ENOG4107U5W ybbr family BAALB65_01520 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) BAALB65_01545 ENOG4106K80 BAALB65_01555 ENOG41067MG lrgb family BAALB65_01565 ENOG41061AU MarR family Transcriptional regulator BAALB65_01580 ENOG4105BZU Histidine kinase BAALB65_01585 ENOG4105WH1 Two component transcriptional regulator luxr family BAALB65_01590 ENOG4105CJ1 ABC, transporter BAALB65_01615 ENOG4106DDH Sporulation-specific SASP protein BAALB65_01630 ENOG4107QTZ amino acid BAALB65_01655 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BAALB65_01660 ENOG4105CXY transporter BAALB65_01700 ENOG4107SCQ Iron-containing alcohol dehydrogenase BAALB65_01705 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR BAALB65_01710 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BAALB65_01715 ENOG4107ZTW SNARE associated Golgi BAALB65_01730 ENOG4105C72 UPF0176 protein BAALB65_01740 ENOG4105CM2 brancheD-chain amino acid aminotransferase BAALB65_01745 ENOG4108IQI permease BAALB65_01750 ENOG4108J5H Homocysteine s-methyltransferase BAALB65_01760 ENOG4105CSV Glutaminase BAALB65_01805 ENOG4105DGI Alkaline phosphatase BAALB65_01810 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) BAALB65_01815 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BAALB65_01820 ENOG4108KN7 Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity) BAALB65_01825 ENOG4107EPV Aminotransferase class V BAALB65_01830 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAALB65_01835 ENOG4105J7D transcriptional regulator BAALB65_01840 ENOG4107RB3 L-asparaginase BAALB65_01845 ENOG4108KTS Acetyltransferase and hydrolase with the alpha beta hydrolase fold BAALB65_01850 ENOG41060AI SEC-C motif BAALB65_01855 ENOG4107SET aldo keto reductase BAALB65_01885 ENOG4105H9W Short-chain dehydrogenase reductase Sdr BAALB65_01895 ENOG4105DSE periplasmic solute binding protein BAALB65_01900 ENOG4105DIK (ABC) transporter BAALB65_01910 ENOG4105DEN Luciferase family BAALB65_01915 ENOG4108N0M stress protein BAALB65_01920 ENOG4106FN3 tellurium resistance protein BAALB65_01925 ENOG4106FN3 tellurium resistance protein BAALB65_01930 ENOG4107TS3 membrane protein, TerC BAALB65_01935 ENOG4108TTB tellurium resistance protein BAALB65_01945 ENOG41079KZ Major Facilitator Superfamily BAALB65_01950 ENOG4108IJ7 Glycine betaine BAALB65_01955 ENOG4107SQ8 Glycine betaine BAALB65_01985 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BAALB65_02015 ENOG4105EIG urea carboxylase-associated protein 1 BAALB65_02020 ENOG4107RA1 nh(3)-dependent nad( ) synthetase BAALB65_02030 ENOG4105I1F Resistance protein BAALB65_02040 ENOG4105DJB Major Facilitator Superfamily BAALB65_02045 ENOG4107Z3Y Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) BAALB65_02050 ENOG4105I82 acetyl xylan esterase BAALB65_02055 ENOG410756H nucleotidyltransferase BAALB65_02065 ENOG4105C26 Dehydrogenase BAALB65_02070 ENOG4105CK7 Sodium proline symporter BAALB65_02075 ENOG4107YHD transcriptional regulator BAALB65_02080 ENOG4105CAY ferredoxin--nadp reductase BAALB65_02085 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BAALB65_02090 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BAALB65_02095 ENOG4108IFG nitrite reductase, (NAD(P)H) BAALB65_02100 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BAALB65_02115 ENOG4105CKI cobalamin synthesis protein BAALB65_02120 ENOG4105E2A Dehydrogenase BAALB65_02125 ENOG4105HHM rdd domain containing protein BAALB65_02135 ENOG4105CS2 ec 3.2.1.21 BAALB65_02150 ENOG41080HJ 6-phospho 3-hexuloisomerase BAALB65_02155 ENOG4108VA3 3-hexulose-6-phosphate synthase BAALB65_02160 ENOG4105KVH Transcriptional regulator BAALB65_02170 ENOG4105CEY Amp-dependent synthetase and ligase BAALB65_02190 ENOG4105CAA catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) BAALB65_02205 ENOG4105CDA abc transporter atp-binding protein BAALB65_02210 ENOG4105DRP amino acid AbC transporter BAALB65_02220 ENOG4106P55 Transcriptional regulator BAALB65_02225 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase BAALB65_02230 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) BAALB65_02235 ENOG41069ZX BAALB65_02240 ENOG41069ZX BAALB65_02245 ENOG4105DUX Transporter BAALB65_02260 ENOG4105E1K spore germination protein BAALB65_02275 ENOG4105CPU Monooxygenase BAALB65_02280 ENOG4108XSB acetyltransferase, (GNAT) family BAALB65_02285 ENOG4105EAB amino acid AbC transporter BAALB65_02290 ENOG4108HW4 amino acid AbC transporter BAALB65_02300 ENOG4105CH2 amidohydrolase BAALB65_02305 ENOG4108PGP mmge prpd family protein BAALB65_02315 ENOG4107WD8 ABC transporter, permease BAALB65_02320 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAALB65_02325 ENOG4105BZU Histidine kinase BAALB65_02345 ENOG4105CFH Aspartokinase BAALB65_02350 ENOG4105DHS permease protein BAALB65_02355 ENOG4105CM4 permease protein BAALB65_02360 ENOG4108IPW abc transporter atp-binding protein BAALB65_02375 ENOG4105R8C Transcriptional regulator BAALB65_02380 ENOG4108DBC nitroreductase BAALB65_02385 ENOG41067V3 Antibiotic biosynthesis monooxygenase BAALB65_02390 ENOG4105YVS arsR family transcriptional regulator BAALB65_02400 ENOG4108JPW Aminotransferase BAALB65_02405 ENOG4105C26 Dehydrogenase BAALB65_02415 ENOG4105H9W Short-chain dehydrogenase reductase Sdr BAALB65_02420 ENOG4105KTB nuclear export factor GLE1 BAALB65_02425 ENOG4108T5E Copper resistance protein BAALB65_02430 ENOG4108ZYE Transcriptional regulator BAALB65_02450 ENOG4107SQ3 mannitol-1-phosphate 5-dehydrogenase BAALB65_02470 ENOG4105E7W lamb ycsf family protein BAALB65_02475 ENOG4105C5A transporter BAALB65_02480 ENOG4105CFM UPF0317 protein BAALB65_02485 ENOG4105P4J Allophanate hydrolase, subunit 1 BAALB65_02495 ENOG4107258 Transcriptional regulator BAALB65_02500 ENOG4105XJB lipolytic protein G-D-S-L family BAALB65_02510 ENOG41061CK Antibiotic biosynthesis monooxygenase BAALB65_02515 ENOG4107RVG penicillin-binding protein BAALB65_02520 ENOG4107QM2 Aldo Keto reductase BAALB65_02525 ENOG4105ETD TRANSCRIPTIONal BAALB65_02535 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BAALB65_02550 ENOG410606W general stress protein BAALB65_02560 ENOG4105VCH membrane BAALB65_02570 ENOG4105C9U ATP-dependent DNA helicase RecQ BAALB65_02585 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BAALB65_02590 ENOG4107R8N Glycosyl transferase, family 2 BAALB65_02600 ENOG4105C0X amino acid BAALB65_02615 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BAALB65_02670 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BAALB65_02685 ENOG4105NRR Uncharacterized protein conserved in bacteria (DUF2188) BAALB65_02690 ENOG4105RXJ BAALB65_02695 ENOG4105KPY Small multidrug resistance protein BAALB65_02700 ENOG4105EU9 BAALB65_02705 ENOG4105QVS general stress protein BAALB65_02710 ENOG41082W1 Cupin 2, conserved barrel domain protein BAALB65_02725 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit BAALB65_02730 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BAALB65_02735 ENOG4108MRH transcriptional regulatory protein BAALB65_02740 ENOG4107QJT sodium dicarboxylate symporter BAALB65_02745 ENOG4106F5Q Membrane BAALB65_02750 ENOG4105CJ1 ABC, transporter BAALB65_02765 ENOG4105FDT acyl-CoA dehydrogenase BAALB65_02785 ENOG4105SZ6 Thioredoxin BAALB65_02790 ENOG4105CPF Cell wall formation (By similarity) BAALB65_02795 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BAALB65_02800 ENOG4105C1J atp-dependent rna helicase BAALB65_02805 ENOG410905X membrane-flanked domain protein BAALB65_02810 ENOG4105CKV Membrane BAALB65_02820 ENOG4107ZSJ Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) BAALB65_02825 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BAALB65_02830 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BAALB65_02840 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BAALB65_02845 ENOG4107MMM Anti-sigma-factor antagonist BAALB65_02850 ENOG4105FUA antagonist BAALB65_02855 ENOG4105QD0 anti-sigma regulatory factor serine threonine protein kinase BAALB65_02860 ENOG4107SGM protein serine threonine phosphatase BAALB65_02865 ENOG4105WN5 stage II sporulation protein BAALB65_02870 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) BAALB65_02880 ENOG41064BQ Phosphatase BAALB65_02895 ENOG410906U SprT-like BAALB65_02945 ENOG4106BHF BAALB65_02950 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BAALB65_02960 ENOG4105C94 Transporter BAALB65_02965 ENOG4105CSH Transporter BAALB65_02985 ENOG4108ZMQ domain protein BAALB65_03000 ENOG4108Z40 Transcriptional regulator BAALB65_03005 ENOG4108RYK Nad-dependent epimerase dehydratase BAALB65_03010 ENOG4105ECK Fatty Acid Desaturase BAALB65_03020 ENOG4105VEQ Cold shock protein BAALB65_03025 ENOG4108VJ1 Transcriptional regulator (CarD family BAALB65_03030 ENOG4105XTG Pfam:DUF156 BAALB65_03035 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BAALB65_03040 ENOG4105C72 UPF0176 protein BAALB65_03045 ENOG4105VFE sira family BAALB65_03050 ENOG4107TPS domain protein BAALB65_03055 ENOG4105VFE sira family BAALB65_03060 ENOG41087NI Sulfite exporter TauE/SafE BAALB65_03080 ENOG4105IRW patatin-like phospholipase family protein BAALB65_03090 ENOG4107RCH Diaminopropionate ammonia-lyase BAALB65_03095 ENOG4108WYP Transcriptional regulator BAALB65_03100 ENOG4105KME endoribonuclease L-psp BAALB65_03110 ENOG4105CH2 amidohydrolase BAALB65_03115 ENOG4108MCI Transcriptional regulator, ARAC family BAALB65_03120 ENOG4105CE7 Amidase, hydantoinase carbamoylase family BAALB65_03125 ENOG4107U9B transcriptional regulator BAALB65_03130 ENOG4105DXI Major Facilitator superfamily BAALB65_03145 ENOG4105PGM cation diffusion facilitator family transporter BAALB65_03150 ENOG4105H3G oxidoreductase BAALB65_03160 ENOG4108VK3 Cupin 2 Conserved Barrel Domain Protein BAALB65_03170 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BAALB65_03205 ENOG4105DWF phosphomethylpyrimidine kinase BAALB65_03220 ENOG4105DQ4 alcohol dehydrogenase BAALB65_03225 ENOG4105VUF Transcriptional regulator BAALB65_03235 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BAALB65_03250 ENOG4105EQ0 Major Facilitator superfamily BAALB65_03255 ENOG4108JGH Tetr family transcriptional regulator BAALB65_03260 ENOG4105T38 integral membrane protein BAALB65_03265 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BAALB65_03280 ENOG4105E2A Dehydrogenase BAALB65_03285 ENOG4105PGS Spore coat protein BAALB65_03295 ENOG4106UW1 Major Facilitator superfamily BAALB65_03320 ENOG4105ENE Histidine kinase BAALB65_03325 ENOG4108VB1 regulatoR BAALB65_03330 ENOG4105EYF MMPL domain protein BAALB65_03350 ENOG4108JYZ YitT family BAALB65_03360 ENOG4105C2C drug resistance transporter, Bcr CflA BAALB65_03365 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BAALB65_03385 ENOG41090E6 transcriptional regulator MERR family BAALB65_03400 ENOG4105F2W methyltransferase BAALB65_03405 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BAALB65_03410 ENOG4105DRR Transcriptional regulator, GntR family BAALB65_03430 ENOG4105FQP Beta-lactamase BAALB65_03435 ENOG41090UD (LipO)protein BAALB65_03440 ENOG4108SUT Major Facilitator Superfamily BAALB65_03445 ENOG4108TZY GntR Family Transcriptional Regulator BAALB65_03450 ENOG4105JXH GntR family transcriptional regulator BAALB65_03455 ENOG4105DJ2 Major Facilitator Superfamily BAALB65_03475 ENOG4107QTZ amino acid BAALB65_03495 ENOG4107QNK )-transporter BAALB65_03535 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) BAALB65_03540 ENOG4105K8N protein family UPF0079, ATPase BAALB65_03545 ENOG41072GX Peptidase M22 Glycoprotease BAALB65_03550 ENOG410801F ribosomal-protein-alanine acetyltransferase BAALB65_03555 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BAALB65_03560 ENOG4105C5H ABC transporter BAALB65_03565 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BAALB65_03570 ENOG4105FF6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity) BAALB65_03575 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) BAALB65_03580 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BAALB65_03590 ENOG4108TYN CAAX amino terminal protease family protein BAALB65_03595 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) BAALB65_03600 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) BAALB65_03605 ENOG4107QJE Chromosome Partitioning Protein BAALB65_03620 ENOG4105PGZ NB-ARC domain BAALB65_03625 ENOG4105CPQ Dehydrogenase BAALB65_03630 ENOG4105CT4 transporter BAALB65_03645 ENOG41087YS Phage shock protein A BAALB65_03650 ENOG4105DQX Zinc finger domain BAALB65_03655 ENOG4108WV1 Pfam:DUF477 BAALB65_03665 ENOG4105EXC Acyl-transferase BAALB65_03670 ENOG4108P49 AntiSigma factor BAALB65_03675 ENOG4105JVQ RNA Polymerase BAALB65_03700 ENOG4107STQ Multicopper oxidase BAALB65_03705 ENOG4105C85 amino acid BAALB65_03715 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BAALB65_03730 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BAALB65_03735 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain BAALB65_03755 ENOG4105E5W Transporter BAALB65_03770 ENOG4105C7N Xanthine uracil vitamin C permease BAALB65_03795 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BAALB65_03800 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BAALB65_03805 ENOG4105C83 adenylosuccinate lyase BAALB65_03810 ENOG4105C8V SAICAR synthetase BAALB65_03815 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BAALB65_03820 ENOG4105D21 Phosphoribosylformylglycinamidine synthase I BAALB65_03825 ENOG4108JIU phosphoribosylformylglycinamidine synthase ii BAALB65_03835 ENOG4105CXB phosphoribosylaminoimidazole synthetase BAALB65_03840 ENOG4108V3E phosphoribosylglycinamide formyltransferase BAALB65_03845 ENOG4105DC1 bifunctional purine biosynthesis protein purh BAALB65_03850 ENOG4105C12 Phosphoribosylglycinamide synthetase BAALB65_03865 ENOG4108R5T secreted protein BAALB65_03870 ENOG4105KGF protein, YerC YecD BAALB65_03875 ENOG4105CBC glutamate synthase BAALB65_03885 ENOG4105C4R Atp-dependent dna helicase BAALB65_03890 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) BAALB65_03900 ENOG4105CRN Aminoglycoside phosphotransferase BAALB65_03905 ENOG4105KT7 mgtC SapB transporter BAALB65_03910 ENOG4105CK7 Sodium proline symporter BAALB65_03915 ENOG4105VB5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) BAALB65_03920 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BAALB65_03925 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) BAALB65_03930 ENOG4108IG5 Transcriptional regulator BAALB65_03940 ENOG4105CBD Diacylglycerol kinase BAALB65_03945 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BAALB65_03960 ENOG4105CJ1 ABC, transporter BAALB65_04015 ENOG4106BHF BAALB65_04020 ENOG4105CDY transcriptional regulatory protein BAALB65_04030 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BAALB65_04045 ENOG4105WEF catalase BAALB65_04050 ENOG4105M18 -acetyltransferase BAALB65_04060 ENOG4105H67 Protein of unknown function (DUF421) BAALB65_04065 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BAALB65_04070 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BAALB65_04085 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein BAALB65_04090 ENOG4108I5D sulfate abc transporter BAALB65_04115 ENOG4106I4J membrane BAALB65_04120 ENOG41082F9 transcriptional regulator BAALB65_04130 ENOG4108R1P BAALB65_04135 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BAALB65_04140 ENOG4105E0M Sulfatase BAALB65_04145 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BAALB65_04155 ENOG41090R9 glycosyltransferase BAALB65_04160 ENOG4107R51 Glycosyl transferase, family 2 BAALB65_04165 ENOG41090R9 glycosyltransferase BAALB65_04170 ENOG4105EU0 Major facilitator Superfamily BAALB65_04175 ENOG4105CUB amino acid BAALB65_04180 ENOG4105C26 Dehydrogenase BAALB65_04185 ENOG4105FKZ Methyl-accepting chemotaxis BAALB65_04190 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BAALB65_04195 ENOG4106WTF Glycosyl transferase, family 2 BAALB65_04200 ENOG4105C5H ABC transporter BAALB65_04205 ENOG4107SWG transcriptional regulator MERR family BAALB65_04210 ENOG4105DXB Major Facilitator superfamily BAALB65_04215 ENOG4105C5H ABC transporter BAALB65_04220 ENOG4105FDU atp-dependent rna helicase BAALB65_04230 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein BAALB65_04245 ENOG4108J20 pectate lyase BAALB65_04250 ENOG4107QPK )-transporter BAALB65_04275 ENOG4108MRH transcriptional regulatory protein BAALB65_04300 ENOG41084X4 Acylphosphatase (EC 3.6.1.7) BAALB65_04305 ENOG4108RPX mosc domain containing protein BAALB65_04325 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BAALB65_04365 ENOG4105C5Y PTS System BAALB65_04370 ENOG4105CG3 alpha amylase, catalytic region BAALB65_04375 ENOG4107414 GntR family transcriptional regulator BAALB65_04380 ENOG4108RCM Nitroreductase BAALB65_04395 ENOG4105CGH 5'-nucleotidase BAALB65_04400 ENOG4107RKG DJ-1/PfpI family BAALB65_04405 ENOG4105ETE Transcriptional regulator (LacI family BAALB65_04410 ENOG4105E2X shikimate dehydrogenase BAALB65_04415 ENOG4105FF2 Type I DHQase BAALB65_04430 ENOG4105KJF protein tyrosine phosphatase BAALB65_04440 ENOG4107U9T Pfam:Ribonuclease_BN BAALB65_04445 ENOG4108ISG Major Facilitator BAALB65_04450 ENOG4105UPD Calcium Proton BAALB65_04460 ENOG4105D8X mechanosensitive ion channel BAALB65_04480 ENOG4106KE4 Dehydrogenase BAALB65_04490 ENOG4105D7N magnesium and cobalt transport protein CorA BAALB65_04500 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BAALB65_04525 ENOG4107RUY (E1 component), alpha subunit BAALB65_04535 ENOG4107QKR Dehydrogenase BAALB65_04545 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BAALB65_04555 ENOG4105F8D glycoside hydrolase family 4 BAALB65_04560 ENOG4108Q3X Transcriptional regulator BAALB65_04565 ENOG4105CI1 PTS System BAALB65_04575 ENOG4105BZ1 (ABC) transporter BAALB65_04580 ENOG4105BZ1 (ABC) transporter BAALB65_04590 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BAALB65_04600 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) BAALB65_04605 ENOG4105U3E Transcriptional regulator BAALB65_04610 ENOG4105DYS nad(p)h dehydrogenase (quinone) BAALB65_04615 ENOG4105H93 Acyltransferase family BAALB65_04630 ENOG4108YYS metal-dependent hydrolase (By similarity) BAALB65_04635 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAALB65_04640 ENOG410834F Transcriptional regulator BAALB65_04650 ENOG4105JAB phenazine biosynthesis protein, phzf family BAALB65_04655 ENOG4107Y03 Nitroreductase BAALB65_04670 ENOG4105ECP epimerase BAALB65_04675 ENOG410902V Modulates RecA activity (By similarity) BAALB65_04685 ENOG4105F27 Major Facilitator BAALB65_04695 ENOG4108TCS Glutamyl endopeptidase BAALB65_04715 ENOG4106AKJ BAALB65_04720 ENOG4105D74 hydrolase BAALB65_04725 ENOG4105CKK Glycosyl transferase, family 2 BAALB65_04730 ENOG4105EJV Membrane BAALB65_04735 ENOG41067AE Membrane-bound metal-dependent hydrolase BAALB65_04740 ENOG4105CEN a g-specific adenine glycosylase BAALB65_04745 ENOG4106BXE BAALB65_04750 ENOG4105CAN Short-chain dehydrogenase reductase Sdr BAALB65_04770 ENOG4105BZ1 (ABC) transporter BAALB65_04775 ENOG4107NBY Membrane BAALB65_04780 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase BAALB65_04785 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BAALB65_04790 ENOG4105G5W regulator Fur family BAALB65_04795 ENOG4105TUA UPF0295 protein BAALB65_04905 ENOG4105EC3 peptidase S51, dipeptidase E BAALB65_04910 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) BAALB65_04915 ENOG4105DNP FAD linked oxidase domain protein BAALB65_04925 ENOG4105DEF Extracellular solute-binding protein, family 5 BAALB65_04935 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAALB65_04940 ENOG4105C3U ABC transporter BAALB65_04945 ENOG4108JQ7 (ABC) transporter BAALB65_04960 ENOG4105E2Y ABC, transporter BAALB65_04965 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BAALB65_04970 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BAALB65_04980 ENOG41082QR Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) BAALB65_04985 ENOG4107D63 BAALB65_04990 ENOG4105VZ8 Transcriptional regulator BAALB65_05005 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BAALB65_05015 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BAALB65_05040 ENOG4105CYN Serine protein kinase BAALB65_05055 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes BAALB65_05060 ENOG4105CW7 secretion protein, HlyD family BAALB65_05065 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAALB65_05070 ENOG4105CS1 NAD(P)H quinone oxidoreductase BAALB65_05085 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BAALB65_05090 ENOG4105CZV ABC transporter BAALB65_05095 ENOG4105CJ1 ABC, transporter BAALB65_05100 ENOG4108TU7 Inherit from COG: (ABC) transporter BAALB65_05105 ENOG4105VEQ Cold shock protein BAALB65_05160 ENOG4108YBP pseudouridine synthase BAALB65_05170 ENOG41080XP Cbs domain BAALB65_05175 ENOG4107YBY Hydrolase BAALB65_05180 ENOG4105DGM nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BAALB65_05190 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BAALB65_05195 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BAALB65_05205 ENOG4108HMR Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) BAALB65_05210 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BAALB65_05220 ENOG4105BZU Histidine kinase BAALB65_05225 ENOG4105WH1 Two component transcriptional regulator luxr family BAALB65_05260 ENOG4105ED1 spovr family BAALB65_05265 ENOG4105G6Z alkaline phosphatase BAALB65_05280 ENOG4105BZN citrate synthase BAALB65_05285 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BAALB65_05290 ENOG4105CUB amino acid BAALB65_05295 ENOG4105C8J )-transporter BAALB65_05305 ENOG4105J37 BAALB65_05310 ENOG4108AEY RNA polymerase sigma factor BAALB65_05315 ENOG4105F6E Acyl-transferase BAALB65_05320 ENOG4105C37 (CBS) domain BAALB65_05330 ENOG4105CHM Aminotransferase BAALB65_05335 ENOG4108MH3 Polyketide beta-ketoacyl acyl carrier protein synthase BAALB65_05340 ENOG4105C37 (CBS) domain BAALB65_05350 ENOG4105WMR Protein CrcB homolog BAALB65_05355 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BAALB65_05365 ENOG4105D64 Mechanosensitive ion channel BAALB65_05370 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BAALB65_05375 ENOG4107VMI polysaccharide deacetylase BAALB65_05380 ENOG4105F0I Aminotransferase BAALB65_05385 ENOG4105W1N transcriptional regulator BAALB65_05390 ENOG4105IIP Membrane BAALB65_05400 ENOG4105BZ1 (ABC) transporter BAALB65_05405 ENOG4105BZ1 (ABC) transporter BAALB65_05430 ENOG410839P BAALB65_05440 ENOG4106MP8 UPF0754 membrane protein BAALB65_05445 ENOG4105WZB UPF0342 protein BAALB65_05450 ENOG4105F1N DNA alkylation repair BAALB65_05460 ENOG4105D4P Coproporphyrinogen iii oxidase BAALB65_05470 ENOG4107S91 Sodium hydrogen exchanger BAALB65_05475 ENOG4105NCW Trka-c domain protein BAALB65_05485 ENOG4105CGU Enoyl-CoA hydratase BAALB65_05495 ENOG4108IUX (ABC) transporter BAALB65_05500 ENOG4105RHA ABC transporter, permease BAALB65_05505 ENOG4107VRP DNA repair exonuclease BAALB65_05510 ENOG4106D4I domain protein BAALB65_05515 ENOG4105EQI Metal Dependent Phosphohydrolase BAALB65_05525 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BAALB65_05575 ENOG4105NBU tryptophan transport protein BAALB65_05580 ENOG4105DXJ Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) BAALB65_05585 ENOG4105K59 histidine triad (HIT) protein BAALB65_05615 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BAALB65_05620 ENOG4105BZ4 penicillin-binding protein BAALB65_05625 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) BAALB65_05630 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BAALB65_05635 ENOG4105C1Q protoporphyrinogen oxidase BAALB65_05645 ENOG4105ECB domain protein BAALB65_05660 ENOG4105DER m42 family BAALB65_05670 ENOG4106AXD BAALB65_05675 ENOG4108RQ5 Beta-lactamase domain-containing protein BAALB65_05680 ENOG4105DF9 Lipoate-protein, ligase BAALB65_05690 ENOG4105CEY Amp-dependent synthetase and ligase BAALB65_05700 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BAALB65_05715 ENOG4108HUF Transporter BAALB65_05720 ENOG4107TB6 phosphoglycerate mutase BAALB65_05730 ENOG4107F3J Amp-dependent synthetase and ligase BAALB65_05735 ENOG4107ZYJ bioY protein BAALB65_05740 ENOG4106YBV Methyl-accepting chemotaxis BAALB65_05760 ENOG4105XVF Competence transcription factor BAALB65_05765 ENOG4108ZMX Domain of unknown function (DU1801) BAALB65_05780 ENOG4105X3H Excalibur domain protein BAALB65_05785 ENOG4105K8R UPF0145 protein BAALB65_05790 ENOG4105E1V na solute symporter BAALB65_05795 ENOG4106CAD Protein of unknown function (DUF3311) BAALB65_05800 ENOG41060YP BAALB65_05815 ENOG4107SCK Monooxygenase BAALB65_05820 ENOG4108INS Transcriptional regulator BAALB65_05825 ENOG4108KK1 membrane protein AbrB duplication BAALB65_05835 ENOG4108IG5 Transcriptional regulator BAALB65_05845 ENOG4108QY0 Membrane BAALB65_05850 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination BAALB65_05855 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation BAALB65_05865 ENOG4105EYH Exonuclease BAALB65_05910 ENOG4105ERH Fumarylacetoacetate hydrolase BAALB65_05925 ENOG4105CAQ asparagine synthetase BAALB65_05935 ENOG4105UQX Mate efflux family protein BAALB65_05940 ENOG4106HBX Transcriptional Regulator AraC Family BAALB65_05945 ENOG4105ETE Transcriptional regulator (LacI family BAALB65_05950 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) BAALB65_05955 ENOG4105SF0 DinB family BAALB65_05965 ENOG4105MYW Pentapeptide repeat protein BAALB65_05970 ENOG4105MA6 gCN5-related N-acetyltransferase BAALB65_05980 ENOG4108VPT UPF0234 protein BAALB65_05985 ENOG4105QNR S1 RNA binding domain protein BAALB65_05990 ENOG4105DIH basic membrane BAALB65_05995 ENOG4105C8Q Methyl-accepting chemotaxis BAALB65_06000 ENOG4107E6A Cytochrome p-450 BAALB65_06010 ENOG4105EPR degv family BAALB65_06015 ENOG4107AYK membrAne BAALB65_06025 ENOG41073B9 BAALB65_06030 ENOG4108KP7 hydrolase BAALB65_06035 ENOG4108MXZ Esterase BAALB65_06040 ENOG4105VG1 fes assembly suf system protein BAALB65_06045 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BAALB65_06050 ENOG4105IQ5 FAD linked oxidase domain protein BAALB65_06060 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase BAALB65_06070 ENOG4105CAS nag kinase BAALB65_06075 ENOG4105C8Y Acetylornithine aminotransferase BAALB65_06080 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BAALB65_06090 ENOG4105DBV ornithine carbamoyltransferase BAALB65_06120 ENOG4107RMD Basic membrane lipoprotein BAALB65_06135 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BAALB65_06140 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BAALB65_06150 ENOG4105C3U ABC transporter BAALB65_06155 ENOG4108JQ7 (ABC) transporter BAALB65_06170 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAALB65_06180 ENOG4105C31 Tryptophanyl-tRNA synthetase BAALB65_06185 ENOG4108J59 Extracellular solute-binding protein, family 5 BAALB65_06190 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BAALB65_06195 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAALB65_06205 ENOG4108JQ7 (ABC) transporter BAALB65_06220 ENOG41090SU Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity) BAALB65_06225 ENOG4108ZCF integral membrane protein BAALB65_06230 ENOG4108SQ7 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis BAALB65_06240 ENOG4105DPN Oligoendopeptidase f BAALB65_06245 ENOG4105T58 Dithiol-disulfide isomerase BAALB65_06250 ENOG4108Z18 K06886 hemoglobin BAALB65_06255 ENOG4105E4C Lytic transglycosylase catalytic BAALB65_06260 ENOG4105MIX Adenylate cyclase BAALB65_06275 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BAALB65_06280 ENOG4105EMS pseudouridine synthase BAALB65_06285 ENOG4107S1Q Phosphatase BAALB65_06300 ENOG4105ETU transcriptional activator (TenA BAALB65_06305 ENOG4108VEU Thiamine monophosphate synthase BAALB65_06325 ENOG4105D06 uba thif-type nad fad binding protein BAALB65_06330 ENOG4105DWF phosphomethylpyrimidine kinase BAALB65_06335 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH BAALB65_06340 ENOG4107A88 BAALB65_06390 ENOG4105ENA helicase BAALB65_06410 ENOG4105CJ1 ABC, transporter BAALB65_06425 ENOG4108ZMI UPF0477 protein BAALB65_06435 ENOG4105C28 cystathionine BAALB65_06440 ENOG4105C28 cystathionine BAALB65_06470 ENOG4106BHF BAALB65_06490 ENOG410907G BAALB65_06545 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAALB65_06560 ENOG4105CKN UDP-glucose-hexose-1-phosphate uridylyltransferase BAALB65_06565 ENOG4105CMR udp-glucose 4-epimerase BAALB65_06570 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) BAALB65_06575 ENOG4105CK1 PTS System BAALB65_06580 ENOG4105VCP PTS System BAALB65_06615 ENOG4105KT7 mgtC SapB transporter BAALB65_06640 ENOG4108IEG Formate dehydrogenase Alpha subunit BAALB65_06650 ENOG4106A3M Cytochrome p-450 BAALB65_06655 ENOG41087PP glycosyltransferase MGT family BAALB65_06665 ENOG4105EXQ uroporphyrinogen iii synthase hem4 BAALB65_06670 ENOG4105C4B ABC transporter, permease BAALB65_06675 ENOG4108IXI (ABC) transporter BAALB65_06685 ENOG4105Q95 Cupin 2, conserved barrel domain protein BAALB65_06700 ENOG4105D2H Uronic isomerase BAALB65_06705 ENOG4105CT4 transporter BAALB65_06710 ENOG4107KJX Transcriptional regulator BAALB65_06715 ENOG4107QZW Altronate oxidoreductase BAALB65_06720 ENOG4105CTX dehydratase BAALB65_06725 ENOG4107TSN permease BAALB65_06740 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BAALB65_06745 ENOG4105KWG Pfam:DUF1696 BAALB65_06750 ENOG4105K7W phage-related replication protein BAALB65_06755 ENOG4105WEF catalase BAALB65_06760 ENOG410635T phage-like element pbsx protein BAALB65_06800 ENOG4108TFU terminase (Small subunit) BAALB65_06805 ENOG4105IG6 Phage terminase, large subunit BAALB65_06810 ENOG4108MDF Phage Portal Protein BAALB65_06835 ENOG41060SN BAALB65_06850 ENOG4105PQS phage protein BAALB65_06855 ENOG4105FR7 XkdM protein, phage-like element PBSX BAALB65_06860 ENOG4105MTC XkdN-like protein BAALB65_06870 ENOG4108FKH Transglycosylase SLT domain BAALB65_06870 ENOG4108FKH Transglycosylase SLT domain BAALB65_06870 ENOG4108FKH Transglycosylase SLT domain BAALB65_06875 ENOG4108WZM domain protein BAALB65_06880 ENOG4105X7F BAALB65_06890 ENOG4105MFU Protein of unknown function (DUF2634) BAALB65_06895 ENOG41066EA baseplate J family protein BAALB65_06900 ENOG410906S phage-like element pbsx protein xkdt BAALB65_06910 ENOG41068G1 BAALB65_06940 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BAALB65_06955 ENOG4105CJ3 phosphate transporter BAALB65_06960 ENOG4107GRR phosphate transport regulator BAALB65_06965 ENOG4107R7I amino acid BAALB65_06975 ENOG4105EDW glycosyl transferase, family 39 BAALB65_06980 ENOG4105CKK Glycosyl transferase, family 2 BAALB65_06985 ENOG4105C0H protease BAALB65_06995 ENOG4108ME1 Peptidase M55 D-aminopeptidase BAALB65_07000 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BAALB65_07005 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAALB65_07010 ENOG4105C3U ABC transporter BAALB65_07020 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BAALB65_07025 ENOG4105DTQ mandelate racemase muconate lactonizing BAALB65_07030 ENOG4107SN7 NLP P60 protein BAALB65_07035 ENOG4108JQ7 (ABC) transporter BAALB65_07040 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BAALB65_07045 ENOG4107TUM Amidinotransferase BAALB65_07050 ENOG4108S4H thioesterase Superfamily protein BAALB65_07055 ENOG4108428 Inherit from COG: -acetyltransferase BAALB65_07065 ENOG41080TC multidrug resistance protein BAALB65_07070 ENOG4105CIY formyltetrahydrofolate deformylase BAALB65_07075 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) BAALB65_07090 ENOG4105K56 Transcriptional regulator BAALB65_07095 ENOG4108ZHJ Organic hydroperoxide resistance protein BAALB65_07110 ENOG4107TVC Glycosyl transferase, family 2 BAALB65_07120 ENOG4105D8G Major Facilitator superfamily BAALB65_07125 ENOG4108Y4K DNA-binding transcriptional activator BAALB65_07130 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) BAALB65_07135 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BAALB65_07145 ENOG4108W7F transporter, permease BAALB65_07150 ENOG4108JJB ABC transporter BAALB65_07155 ENOG4105NSK ABC superfamily ATP binding cassette transporter membrane protein BAALB65_07160 ENOG4105VRS hydrolase family 18 BAALB65_07180 ENOG4105CJW magnesium transporter BAALB65_07185 ENOG4105V75 Transcriptional regulator BAALB65_07210 ENOG4105DQE DNA ligase BAALB65_07215 ENOG4105FDF Could be involved in DNA repair (By similarity) BAALB65_07220 ENOG4107T5V SNARE associated Golgi BAALB65_07225 ENOG4107TS3 membrane protein, TerC BAALB65_07230 ENOG4108WZW RNA polymerase sigma BAALB65_07240 ENOG410681C small acid-soluble spore protein BAALB65_07250 ENOG4105D0M Protease HtpX homolog BAALB65_07260 ENOG410900G Protein of unknown function (DUF421) BAALB65_07270 ENOG4108TGC Acyltransferase BAALB65_07275 ENOG4105BZU Histidine kinase BAALB65_07280 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BAALB65_07285 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) BAALB65_07295 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BAALB65_07305 ENOG4105DT1 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate BAALB65_07310 ENOG4105JAS Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity) BAALB65_07315 ENOG4107QY0 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BAALB65_07320 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) BAALB65_07330 ENOG4105BZU Histidine kinase BAALB65_07335 ENOG41090MY MarR family Transcriptional regulator BAALB65_07340 ENOG4105ER2 Ompa motb domain protein BAALB65_07345 ENOG4105E14 MotA TolQ exbB proton channel BAALB65_07360 ENOG4108K88 Membrane BAALB65_07370 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) BAALB65_07375 ENOG4107ZAE 6-carboxy-5,6,7,8-tetrahydropterin synthase BAALB65_07380 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BAALB65_07385 ENOG4105CSD Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) BAALB65_07395 ENOG4105CBZ Short-chain dehydrogenase reductase Sdr BAALB65_07420 ENOG4105F0V Cell wall hydrolase BAALB65_07435 ENOG4105C59 p-type ATPase BAALB65_07440 ENOG4105DC7 peptidase M24 BAALB65_07450 ENOG4105CID antiterminator BAALB65_07460 ENOG4105KRI phosphocarrier protein (HPr BAALB65_07465 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BAALB65_07475 ENOG4105F6S Spore photoproduct lyase BAALB65_07480 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BAALB65_07485 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BAALB65_07490 ENOG4105K4I Scp-like extracellular BAALB65_07500 ENOG4105BZU Histidine kinase BAALB65_07505 ENOG4105CHM Aminotransferase BAALB65_07515 ENOG4107R88 Chemotaxis protein (CheV) BAALB65_07520 ENOG4105UIN BAALB65_07530 ENOG4107Y2H ErfK ybiS ycfS ynhG family protein BAALB65_07540 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BAALB65_07550 ENOG4105EPM Diguanylate phosphodiesterase BAALB65_07555 ENOG4107IN1 Protein of unknown function (DUF1797) BAALB65_07560 ENOG4108XRC Protein of unknown function (DUF458) BAALB65_07590 ENOG4105NQC Flavodoxin BAALB65_07610 ENOG4105D8X mechanosensitive ion channel BAALB65_07615 ENOG4107R19 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BAALB65_07630 ENOG41082CS Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) BAALB65_07635 ENOG4105D06 uba thif-type nad fad binding protein BAALB65_07640 ENOG4105CVM Molybdenum cofactor synthesis domain protein BAALB65_07645 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BAALB65_07650 ENOG4108ZAF Molybdopterin BAALB65_07655 ENOG41067WU Molybdopterin converting factor (Subunit 1) BAALB65_07665 ENOG4107X8C Efflux transporter RND family MFP subunit BAALB65_07670 ENOG4105C19 ABC transporter BAALB65_07675 ENOG4107RBB ABC transporter, permease BAALB65_07680 ENOG4105E98 transcriptional regulator DeoR family BAALB65_07685 ENOG4105DE4 1-phosphofructokinase BAALB65_07690 ENOG4105DM4 PTS System BAALB65_07705 ENOG4105C5H ABC transporter BAALB65_07710 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BAALB65_07740 ENOG4105BZU Histidine kinase BAALB65_07750 ENOG4107ZYR domain protein BAALB65_07755 ENOG4105CPN adenine deaminase BAALB65_07760 ENOG4105CN5 Metallo-Beta-Lactamase BAALB65_07765 ENOG4106148 UPF0356 protein BAALB65_07770 ENOG4108X4Q Hydrolase BAALB65_07775 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BAALB65_07795 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BAALB65_07800 ENOG4105C0W non-ribosomal peptide synthetase BAALB65_07805 ENOG4107SQU synthase BAALB65_07810 ENOG4105C0W non-ribosomal peptide synthetase BAALB65_07815 ENOG4107SQU synthase BAALB65_07820 ENOG4107SQU synthase BAALB65_07825 ENOG4107SQU synthase BAALB65_07830 ENOG4105C0W non-ribosomal peptide synthetase BAALB65_07835 ENOG4105FQP Beta-lactamase BAALB65_07845 ENOG4105CPP Dehydrogenase, E1 component BAALB65_07850 ENOG4105C7S Dehydrogenase BAALB65_07855 ENOG4107QN2 dihydrolipoyl dehydrogenase BAALB65_07875 ENOG4105CXN decarboxylase BAALB65_07880 ENOG4105WBI UPF0223 protein BAALB65_07900 ENOG4105ECY inositol monophosphatase BAALB65_07910 ENOG4105D4Y metalloprotease BAALB65_07945 ENOG4105CI3 gtp-binding protein typa BAALB65_07950 ENOG4105QA2 BAALB65_07965 ENOG4108IAB Phoh family BAALB65_07975 ENOG4105CSV Glutaminase BAALB65_07985 ENOG4105CNI cell division protein FtsW BAALB65_07990 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BAALB65_08000 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) BAALB65_08010 ENOG4105BZ9 Cytochrome C oxidase, subunit I BAALB65_08015 ENOG4105CCU oxidase (Subunit III) BAALB65_08020 ENOG41064X9 cytochrome C oxidase subunit IV BAALB65_08035 ENOG41080XQ Signal transduction protein with cbs domains BAALB65_08040 ENOG4106UY4 Inherit from COG: Scp-like extracellular BAALB65_08070 ENOG4106H78 methyltransferase BAALB65_08075 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) BAALB65_08080 ENOG4105H20 Sporulation integral membrane protein YlbJ BAALB65_08085 ENOG4105D78 K07001 NTE family protein BAALB65_08090 ENOG41063PX domain protein BAALB65_08095 ENOG4105CDE UPF0348 protein BAALB65_08100 ENOG4105KNH Nucleic acid-binding protein BAALB65_08105 ENOG41067VY 50S ribosomal protein L32 BAALB65_08130 ENOG4108V6E Cell division protein mraZ BAALB65_08135 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) BAALB65_08145 ENOG4105CJN penicillin-binding protein BAALB65_08150 ENOG4105CJN penicillin-binding protein BAALB65_08155 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BAALB65_08160 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) BAALB65_08165 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) BAALB65_08170 ENOG4105CNI cell division protein FtsW BAALB65_08175 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BAALB65_08180 ENOG4105D4A Cell wall formation (By similarity) BAALB65_08185 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) BAALB65_08190 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BAALB65_08195 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BAALB65_08205 ENOG4105FFI sigma-e processing peptidase spoiiga BAALB65_08210 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAALB65_08220 ENOG4105DKW ABC transporter BAALB65_08230 ENOG4105WR5 sporulation protein, YlmC YmxH family BAALB65_08235 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BAALB65_08240 ENOG4105DFA alanine racemase domain protein BAALB65_08245 ENOG4105VR5 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity) BAALB65_08250 ENOG41067XK integral membrane protein BAALB65_08255 ENOG4105DBK s4 domain protein BAALB65_08270 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BAALB65_08280 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) BAALB65_08285 ENOG4105C34 Pseudouridine synthase BAALB65_08290 ENOG4108UK1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity) BAALB65_08300 ENOG4105CXT aspartate transcarbamylase BAALB65_08310 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BAALB65_08315 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain BAALB65_08320 ENOG4105DF0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity) BAALB65_08325 ENOG4107RY0 Catalyzes the conversion of dihydroorotate to orotate (By similarity) BAALB65_08330 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) BAALB65_08335 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) BAALB65_08350 ENOG4107RIQ Sulfate adenylate transferase BAALB65_08360 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BAALB65_08365 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BAALB65_08370 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BAALB65_08380 ENOG4105F23 Fibronectin-binding protein BAALB65_08390 ENOG4105DSJ YicC domain protein BAALB65_08395 ENOG4105KC4 UPF0296 protein BAALB65_08400 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) BAALB65_08410 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BAALB65_08415 ENOG4105C25 Primosomal protein n' BAALB65_08420 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BAALB65_08425 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) BAALB65_08430 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BAALB65_08435 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs BAALB65_08440 ENOG4108ZF3 Phosphatase BAALB65_08445 ENOG4105D9P serine threonine protein kinase BAALB65_08450 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BAALB65_08455 ENOG4105DJV ribulose-phosphate 3-epimerase BAALB65_08460 ENOG4105FJ0 thiamine BAALB65_08470 ENOG4105VB9 50S ribosomal protein l28 BAALB65_08475 ENOG4108ZAA Alkaline-shock protein BAALB65_08480 ENOG4105DP4 dak2 domain fusion protein ylov BAALB65_08490 ENOG4105EJQ L-serine dehydratase BAALB65_08495 ENOG4105CB5 ATP-dependent DNA helicase recG BAALB65_08500 ENOG4108VVV Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity) BAALB65_08505 ENOG4105C6B Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity) BAALB65_08510 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BAALB65_08515 ENOG4105CHR reductase BAALB65_08520 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) BAALB65_08525 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) BAALB65_08530 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BAALB65_08535 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BAALB65_08545 ENOG4105VBN Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity) BAALB65_08555 ENOG4105K5M 30s ribosomal protein S16 BAALB65_08560 ENOG4108BW8 UPF0109 protein BAALB65_08575 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) BAALB65_08580 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) BAALB65_08585 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BAALB65_08590 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) BAALB65_08600 ENOG4105VM1 flagellar BAALB65_08605 ENOG4105CMV Succinyl-CoA synthetase subunit beta BAALB65_08610 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BAALB65_08615 ENOG4105C79 DNA protecting protein DprA BAALB65_08620 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BAALB65_08625 ENOG4107QXI Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity) BAALB65_08630 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BAALB65_08635 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) BAALB65_08640 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) BAALB65_08650 ENOG4105Q75 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BAALB65_08655 ENOG4108ZC9 flagellar basal-body rod protein flgc BAALB65_08660 ENOG4105VQ0 flagellar hook-basal body complex protein fliE BAALB65_08665 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) BAALB65_08670 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BAALB65_08685 ENOG4106YF4 Flagellar biosynthesis chaperone BAALB65_08695 ENOG410696Y Flagellar hook-length control protein BAALB65_08700 ENOG410822I Flagellar hook capping protein BAALB65_08705 ENOG4108JQA flagellar BAALB65_08710 ENOG41068WV flagellar FlbD family protein BAALB65_08720 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BAALB65_08725 ENOG4105DD5 Flagellar motor switch protein BAALB65_08730 ENOG4107YTP response regulator receiver protein BAALB65_08740 ENOG4105CN7 Flagellar biosynthetic protein FliP BAALB65_08745 ENOG4105VS8 Flagellar biosynthetic protein fliq BAALB65_08750 ENOG4105D19 Role in flagellar biosynthesis (By similarity) BAALB65_08755 ENOG4105D00 flagellar biosynthetic protein flhB BAALB65_08760 ENOG4105D7B Flagellar biosynthesis protein flha BAALB65_08765 ENOG4105FZW flagellar biosynthesis regulator FlhF BAALB65_08775 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) BAALB65_08780 ENOG4105CBS Chea signal transduction histidine kinase BAALB65_08785 ENOG410807Z Modulation of CheA activity in response to attractants (Chemotaxis BAALB65_08795 ENOG4108Z4W Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity) BAALB65_08800 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAALB65_08810 ENOG4105CE9 30S ribosomal protein S2 BAALB65_08820 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BAALB65_08825 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) BAALB65_08830 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BAALB65_08835 ENOG4105KNE Phosphatidate cytidylyltransferase BAALB65_08845 ENOG4105DZP Membrane-associated zinc metalloprotease BAALB65_08850 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) BAALB65_08855 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BAALB65_08860 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) BAALB65_08865 ENOG4105CHV Transcription elongation factor NusA BAALB65_08870 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BAALB65_08875 ENOG4105VHM ribosomal protein BAALB65_08880 ENOG4107EEM One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) BAALB65_08885 ENOG4105W7A Protein of unknown function (DUF503) BAALB65_08890 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) BAALB65_08895 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) BAALB65_08900 ENOG4105DTN riboflavin biosynthesis protein ribF BAALB65_08905 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) BAALB65_08910 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) BAALB65_08920 ENOG4105C1V Peptidase, M16 BAALB65_08930 ENOG4105E35 Dipicolinate synthase subunit A BAALB65_08935 ENOG4108S0H Dipicolinic acid synthetase, b subunit BAALB65_08940 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BAALB65_08950 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BAALB65_08960 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BAALB65_08970 ENOG4105CNU cell division protein FtsK BAALB65_08975 ENOG4105FDP GntR family transcriptional regulator BAALB65_08990 ENOG4105EYF MMPL domain protein BAALB65_09005 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BAALB65_09010 ENOG4105XZV Protein of unknown function (DUF3243) BAALB65_09025 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BAALB65_09030 ENOG4105CEV competence damage-inducible protein BAALB65_09035 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) BAALB65_09040 ENOG4108A04 Beta-lactamase BAALB65_09050 ENOG4105D48 metallophosphoesterase BAALB65_09055 ENOG4105MCT stage V sporulation protein S BAALB65_09060 ENOG4105CPQ Dehydrogenase BAALB65_09065 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BAALB65_09070 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BAALB65_09090 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) BAALB65_09135 ENOG4108151 Beta-lactamase domain protein BAALB65_09140 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BAALB65_09145 ENOG4108JA1 polyketide synthase BAALB65_09150 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BAALB65_09155 ENOG41062T2 Acyl carrier protein BAALB65_09160 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase BAALB65_09165 ENOG4108MGH Enoyl-CoA hydratase BAALB65_09170 ENOG4108KQ6 Enoyl-CoA hydratase BAALB65_09175 ENOG4105C0W non-ribosomal peptide synthetase BAALB65_09180 ENOG4107SQU synthase BAALB65_09190 ENOG4105C0W non-ribosomal peptide synthetase BAALB65_09200 ENOG4106A3M Cytochrome p-450 BAALB65_09205 ENOG4105WFK nuclease BAALB65_09210 ENOG4105XPP Protein of unknown function (DUF1275) BAALB65_09220 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BAALB65_09230 ENOG4105K7W phage-related replication protein BAALB65_09235 ENOG4108X3M OsmC Ohr family protein BAALB65_09260 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) BAALB65_09285 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BAALB65_09290 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BAALB65_09295 ENOG4105U6W MutT NUDIX family protein BAALB65_09300 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BAALB65_09310 ENOG4106F1P AAA ATPase, central domain protein BAALB65_09315 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BAALB65_09320 ENOG4105CXI aluminum resistance protein BAALB65_09325 ENOG4105KV4 Transcriptional regulator BAALB65_09330 ENOG4105C5F glutamine synthetase BAALB65_09380 ENOG4105CT4 transporter BAALB65_09385 ENOG4105DSG hydrolase family 43 BAALB65_09395 ENOG4105C93 Xylose Isomerase BAALB65_09400 ENOG4105CMG Carbohydrate kinase BAALB65_09405 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BAALB65_09430 ENOG4105D29 Helix-turn-helix type 11 domain protein BAALB65_09435 ENOG4105SF0 DinB family BAALB65_09440 ENOG4105DQ4 alcohol dehydrogenase BAALB65_09470 ENOG4105EPI acetyltransferase, (GNAT) family BAALB65_09475 ENOG4106BHF BAALB65_09480 ENOG4106ANW SMI1_KNR4 BAALB65_09520 ENOG4108M1A Chitin-binding protein BAALB65_09545 ENOG4107YUK This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) BAALB65_09550 ENOG4105K7W phage-related replication protein BAALB65_09570 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) BAALB65_09580 ENOG4108SVB resolvase BAALB65_09585 ENOG4105VPS UPF0291 protein BAALB65_09590 ENOG4105CV1 Transketolase (EC 2.2.1.1) BAALB65_09600 ENOG4105VXM UPF0154 protein BAALB65_09610 ENOG4107QIV Cytochrome c biogenesis protein BAALB65_09645 ENOG4108I0Z Aconitate hydratase BAALB65_09650 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BAALB65_09665 ENOG41067CD Small, acid-soluble spore protein Tlp BAALB65_09675 ENOG4105MI2 BAALB65_09680 ENOG4105W8X HesB YadR YfhF-family protein BAALB65_09685 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BAALB65_09690 ENOG4105K4P CoA-binding domain protein BAALB65_09695 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BAALB65_09720 ENOG4105CPQ Dehydrogenase BAALB65_09725 ENOG4108UHU Aldolase BAALB65_09730 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) BAALB65_09735 ENOG4105DMW Dehydrogenase reductase BAALB65_09745 ENOG4108I5G Major Facilitator superfamily BAALB65_09760 ENOG4105FVX BAALB65_09770 ENOG4107R39 (ABC) transporter BAALB65_09805 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAALB65_09815 ENOG4107SYN Glycosyl hydrolases family 43 BAALB65_09845 ENOG4105DTD Dehydrogenase BAALB65_09850 ENOG4108IIH CoA-transferase subunit B BAALB65_09855 ENOG4105D6N CoA-transferase, subunit a BAALB65_09860 ENOG4105CY2 Citrate transporter BAALB65_09865 ENOG4106A3M Cytochrome p-450 BAALB65_09870 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) BAALB65_09875 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) BAALB65_09880 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BAALB65_09885 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BAALB65_09890 ENOG4108W8G Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP (By similarity) BAALB65_09900 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BAALB65_09905 ENOG4107T5V SNARE associated Golgi BAALB65_09910 ENOG4107QX3 carboxylase BAALB65_09915 ENOG4105E39 Enoyl-CoA hydratase BAALB65_09920 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BAALB65_09925 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BAALB65_09930 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BAALB65_09935 ENOG4105CEY Amp-dependent synthetase and ligase BAALB65_09940 ENOG4105C1G acyl-Coa dehydrogenase BAALB65_09945 ENOG4105F32 YngK protein BAALB65_09950 ENOG4106U2H Protein of unknown function (DUF1360) BAALB65_09960 ENOG4105CEY Amp-dependent synthetase and ligase BAALB65_09965 ENOG4105C0W non-ribosomal peptide synthetase BAALB65_09975 ENOG4105C0W non-ribosomal peptide synthetase BAALB65_09985 ENOG4107RVU D-Ala-D-Ala carboxypeptidase 3 (S13) family BAALB65_09990 ENOG4108N2V aldose 1-epimerase BAALB65_09995 ENOG4107QJQ Mate efflux family protein BAALB65_10020 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) BAALB65_10025 ENOG4108RWP Major Facilitator Superfamily protein BAALB65_10030 ENOG4105WAB arsR family transcriptional regulator BAALB65_10035 ENOG4105C22 threonyL-tRNA synthetase BAALB65_10040 ENOG4108KSA LysR family transcriptional regulator BAALB65_10045 ENOG4105CB2 alcohol dehydrogenase BAALB65_10055 ENOG4105BZ8 glutamate synthase BAALB65_10060 ENOG4105CBC glutamate synthase BAALB65_10065 ENOG4105C5Q Transcriptional regulator BAALB65_10070 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) BAALB65_10095 ENOG4108UB7 BAALB65_10100 ENOG4105IE8 Alpha-ketoglutarate permease BAALB65_10105 ENOG4107U6E carbohydrate kinase FGGY BAALB65_10110 ENOG4108M3J Dehydrogenase BAALB65_10115 ENOG4108J2R molybdopterin oxidoreductase BAALB65_10140 ENOG4106ANW SMI1_KNR4 BAALB65_10145 ENOG4106BHF BAALB65_10150 ENOG4108Z7R Chaperone CsaA BAALB65_10155 ENOG4105FTV AraC Family Transcriptional Regulator BAALB65_10165 ENOG4108W8B Beta-lactamase domain protein BAALB65_10175 ENOG4105KTU Transcriptional regulator, arsr family BAALB65_10185 ENOG4108SJC Membrane BAALB65_10210 ENOG41069ER domain protein BAALB65_10215 ENOG4105C9U ATP-dependent DNA helicase RecQ BAALB65_10225 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BAALB65_10230 ENOG4105SCY DNAK suppressor BAALB65_10275 ENOG4105C26 Dehydrogenase BAALB65_10280 ENOG4105EWU Squalene--hopene cyclase BAALB65_10285 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BAALB65_10290 ENOG4105C8J )-transporter BAALB65_10295 ENOG4105C09 Bile acid BAALB65_10305 ENOG4105C7S Dehydrogenase BAALB65_10310 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 BAALB65_10315 ENOG4107T89 von Willebrand factor, type A BAALB65_10320 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BAALB65_10330 ENOG4105K4H Nlp p60 protein BAALB65_10335 ENOG41087PP glycosyltransferase MGT family BAALB65_10345 ENOG4107QMU Mate efflux family protein BAALB65_10350 ENOG4106SCS STAS domain BAALB65_10370 ENOG4105FR1 rard protein BAALB65_10385 ENOG41090U3 tautomerase BAALB65_10405 ENOG4105FBA Phospholipase Carboxylesterase BAALB65_10420 ENOG4105E1V na solute symporter BAALB65_10430 ENOG4105CS2 ec 3.2.1.21 BAALB65_10435 ENOG4108S3Y transcriptional regulator BAALB65_10455 ENOG4108VXD carboxy-peptidase BAALB65_10460 ENOG4105D3A purine nucleoside phosphorylase DeoD-type BAALB65_10470 ENOG4106Z5R BAALB65_10475 ENOG410841Q phosphoesterase PA-phosphatase related protein BAALB65_10505 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BAALB65_10510 ENOG4108TSC N-acetyltransferase BAALB65_10515 ENOG4107S4Y M20 DapE family protein YgeY BAALB65_10530 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BAALB65_10535 ENOG4105FTQ Dna gyrase BAALB65_10585 ENOG4106Y37 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity) BAALB65_10615 ENOG410780I phosphoprotein phosphatase activity BAALB65_10640 ENOG4106ANW SMI1_KNR4 BAALB65_10695 ENOG4107NTZ BAALB65_10725 ENOG4106ANW SMI1_KNR4 BAALB65_10730 ENOG4106BHF BAALB65_10740 ENOG4107Y9E nuclease BAALB65_10770 ENOG4105E0X reductase BAALB65_10775 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BAALB65_10785 ENOG4105QZP Uncharacterized protein conserved in bacteria (DUF2140) BAALB65_10790 ENOG41090WU lipolytic protein G-D-S-L family BAALB65_10795 ENOG4108KF3 Electron transport protein SCO1 SenC BAALB65_10805 ENOG4105C7B Threonine dehydratase BAALB65_10815 ENOG4108UT2 hemolysin iii BAALB65_10830 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) BAALB65_10835 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) BAALB65_10845 ENOG4107YX5 Pfam:DUF548 BAALB65_10850 ENOG4108Y6J UPF0403 protein BAALB65_10855 ENOG4105C01 Dihydroxy-acid dehydratase BAALB65_10870 ENOG4108V06 Glutathione peroxidase BAALB65_10875 ENOG4105CVG Homoserine O-transsuccinylase BAALB65_10915 ENOG41081VK Ribonuclease BAALB65_10940 ENOG410890F Dynamin family BAALB65_10955 ENOG41065KQ synthase BAALB65_10995 ENOG4105C2W permease BAALB65_11000 ENOG4108UPS Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity) BAALB65_11005 ENOG4105CTD carboxy-peptidase BAALB65_11010 ENOG4105DVT helicase BAALB65_11025 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BAALB65_11035 ENOG4105XWG Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity) BAALB65_11040 ENOG4108UKS UPF0398 protein BAALB65_11050 ENOG4107X2U Inherit from COG: Exonuclease-like protein BAALB65_11055 ENOG4108I5C dEAD DEAH box helicase BAALB65_11100 ENOG4108UI2 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity) BAALB65_11105 ENOG4105BZ4 penicillin-binding protein BAALB65_11115 ENOG4105CSM endonuclease III BAALB65_11125 ENOG4105C5S asparaginyl-tRNA synthetase BAALB65_11130 ENOG4105CHM Aminotransferase BAALB65_11140 ENOG4105YAC BAALB65_11145 ENOG4105DVT helicase BAALB65_11150 ENOG4108Z2X Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity) BAALB65_11160 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) BAALB65_11170 ENOG4105D4J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate BAALB65_11175 ENOG4105CPK Glycosyl transferase (Group 1 BAALB65_11180 ENOG4105FJR Lmbe family BAALB65_11185 ENOG4108Z5K methylglyoxal synthase BAALB65_11190 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) BAALB65_11195 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BAALB65_11200 ENOG4108JYZ YitT family BAALB65_11205 ENOG4105F0F Oxalate decarboxylase BAALB65_11225 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BAALB65_11245 ENOG41068YB TPR repeat-containing protein BAALB65_11250 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase BAALB65_11260 ENOG4105CIH Imidazole acetol-phosphate transaminase BAALB65_11270 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) BAALB65_11275 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase BAALB65_11280 ENOG4105DK0 Indole-3-glycerol phosphate synthase BAALB65_11290 ENOG4105CRQ synthase (Component I) BAALB65_11295 ENOG4105KHN chorismate mutase BAALB65_11305 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BAALB65_11310 ENOG4105BZU Histidine kinase BAALB65_11315 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) BAALB65_11320 ENOG4105EAH synthase BAALB65_11325 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BAALB65_11330 ENOG4105XXQ heptaprenyl diphosphate synthase component I BAALB65_11335 ENOG4105WP2 Tryptophan RNA-binding attenuator protein BAALB65_11340 ENOG4105EUJ GTP cyclohydrolase i BAALB65_11345 ENOG4105K70 DNA-binding protein BAALB65_11350 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BAALB65_11365 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase BAALB65_11370 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) BAALB65_11390 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) BAALB65_11395 ENOG4105CAT Cytidine monophosphate kinase BAALB65_11405 ENOG4105MSI germination protein ypeb BAALB65_11415 ENOG4108PNU Involved in the degradation of specific anti-sigma factors (By similarity) BAALB65_11420 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BAALB65_11435 ENOG4107RGJ metallophosphoesterase BAALB65_11450 ENOG4105I7S Abortive infection protein BAALB65_11455 ENOG4105C9U ATP-dependent DNA helicase RecQ BAALB65_11460 ENOG4105T7X BAALB65_11470 ENOG4108SAX Membrane BAALB65_11475 ENOG4108JQ1 Dehydrogenase BAALB65_11490 ENOG4105BZU Histidine kinase BAALB65_11495 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAALB65_11500 ENOG4105CRE cytochrome C BAALB65_11505 ENOG4107TWT Cytochrome c biogenesis protein BAALB65_11515 ENOG4105FE9 pseudouridine synthase BAALB65_11525 ENOG4108JIC nucleoside recognition domain protein BAALB65_11530 ENOG4105DZ1 carboxypeptidase BAALB65_11540 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) BAALB65_11545 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) BAALB65_11570 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) BAALB65_11575 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) BAALB65_11580 ENOG4108R6K riboflavin synthase, subunit alpha BAALB65_11605 ENOG4107ZE5 PPIases accelerate the folding of proteins BAALB65_11610 ENOG4105PTM secreted protein BAALB65_11615 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BAALB65_11625 ENOG4105G6R Stage v sporulation protein ae BAALB65_11635 ENOG4105CZ3 stage V sporulation protein ad BAALB65_11640 ENOG41090VF Stage v sporulation protein ac BAALB65_11655 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAALB65_11660 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) BAALB65_11665 ENOG41082AN stage II sporulation protein BAALB65_11670 ENOG4105DZ1 carboxypeptidase BAALB65_11675 ENOG4105CB1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) BAALB65_11680 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) BAALB65_11685 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BAALB65_11695 ENOG4105I3K Ferric uptake regulator, Fur family BAALB65_11700 ENOG4105MZ9 stage II sporulation protein m BAALB65_11720 ENOG4105DFD Na H antiporter BAALB65_11725 ENOG4108IJ0 Aspartate ammonia-lyase BAALB65_11730 ENOG4105HDK L-asparaginase BAALB65_11735 ENOG4108IMY Transcriptional regulator BAALB65_11745 ENOG4108YZ4 nudix hydrolase BAALB65_11755 ENOG4105CPC Aldo Keto reductase BAALB65_11775 ENOG4106HZJ BAALB65_11780 ENOG4105RHY Pfam:UPF0157 BAALB65_11785 ENOG4105KAC Antibiotic biosynthesis monooxygenase BAALB65_11790 ENOG4108XET gCN5-related N-acetyltransferase BAALB65_11795 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BAALB65_11810 ENOG4105C02 permease BAALB65_11820 ENOG4105HRU Glyoxalase Bleomycin resistance protein (Dioxygenase BAALB65_11825 ENOG4105CS9 pantothenic acid kinase BAALB65_11835 ENOG4108IXY short-chain dehydrogenase reductase BAALB65_11840 ENOG41069FQ Metallo-beta-lactamase superfamily BAALB65_11845 ENOG4105II7 pyrroline-5-carboxylate reductase BAALB65_11850 ENOG4108KQ6 Enoyl-CoA hydratase BAALB65_11855 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase BAALB65_11875 ENOG4105C0W non-ribosomal peptide synthetase BAALB65_11880 ENOG4105C0W non-ribosomal peptide synthetase BAALB65_11890 ENOG4105C0W non-ribosomal peptide synthetase BAALB65_11900 ENOG4105CHR reductase BAALB65_11905 ENOG4105CEY Amp-dependent synthetase and ligase BAALB65_11920 ENOG4107QKG PfaD family BAALB65_11925 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BAALB65_11935 ENOG4108K70 Transcriptional regulator BAALB65_11945 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BAALB65_11955 ENOG410861F 50S ribosomal protein L33 BAALB65_11960 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BAALB65_11965 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BAALB65_11970 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BAALB65_11975 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BAALB65_11985 ENOG4107XQC Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity) BAALB65_11990 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BAALB65_11995 ENOG4108HNZ carboxyl transferase BAALB65_12000 ENOG4108ZVT methylmalonyl-coA epimerase BAALB65_12005 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BAALB65_12010 ENOG4108QEG Membrane BAALB65_12015 ENOG4105CDA abc transporter atp-binding protein BAALB65_12020 ENOG4105E5Q amino acid AbC transporter BAALB65_12025 ENOG4108HW3 (ABC) transporter BAALB65_12030 ENOG4108Y6J UPF0403 protein BAALB65_12035 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BAALB65_12040 ENOG4105C7S Dehydrogenase BAALB65_12045 ENOG4105CPP Dehydrogenase, E1 component BAALB65_12060 ENOG4105CKM Branched-chain carboxylic acid kinase BAALB65_12065 ENOG4107RDP Dehydrogenase BAALB65_12075 ENOG4108JUB Transcriptional regulator BAALB65_12080 ENOG4106CCJ Protein of unknown function (DUF2627) BAALB65_12085 ENOG4105CR4 methylisocitrate lyase BAALB65_12090 ENOG4105DXD 2-methylcitrate dehydratase BAALB65_12100 ENOG4105C1G acyl-Coa dehydrogenase BAALB65_12105 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BAALB65_12115 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BAALB65_12120 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BAALB65_12140 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BAALB65_12155 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BAALB65_12160 ENOG4107QQR Sporulation BAALB65_12165 ENOG4105S1Z Stage IV sporulation protein B BAALB65_12170 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BAALB65_12175 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) BAALB65_12180 ENOG4105DX0 Hemolysin A BAALB65_12185 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) BAALB65_12190 ENOG4105CTB Polyprenyl synthetase BAALB65_12195 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) BAALB65_12200 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) BAALB65_12205 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) BAALB65_12210 ENOG4105M7K Involved in the transcription termination process (By similarity) BAALB65_12215 ENOG4108ZSR alkaline shock protein BAALB65_12220 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BAALB65_12240 ENOG410644B Stage III sporulation protein af BAALB65_12250 ENOG4105KQ4 Stage iii sporulation protein ad BAALB65_12255 ENOG4108CQH stage III sporulation protein AC BAALB65_12260 ENOG4105KR5 Stage iii sporulation protein BAALB65_12265 ENOG4105CD2 stage iii sporulation protein aa BAALB65_12275 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) BAALB65_12280 ENOG4105DC7 peptidase M24 BAALB65_12290 ENOG4105CBJ Metal-dependent enzyme BAALB65_12310 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) BAALB65_12315 ENOG4105WZW rhodanese family BAALB65_12320 ENOG4107RGW The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor BAALB65_12330 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) BAALB65_12335 ENOG4105C0D helicase BAALB65_12350 ENOG4108IMY Transcriptional regulator BAALB65_12360 ENOG4105VFR signal peptidase BAALB65_12420 ENOG4105C37 (CBS) domain BAALB65_12445 ENOG4105C5X domain protein BAALB65_12490 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BAALB65_12495 ENOG4105WDJ 50S ribosomal protein L33 BAALB65_12505 ENOG41068DG YceG-like family BAALB65_12510 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BAALB65_12515 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BAALB65_12520 ENOG4105E2Z phosphate ABC transporter (Permease BAALB65_12525 ENOG4105C8U phosphate abc transporter BAALB65_12530 ENOG4105CVA phosphate BAALB65_12535 ENOG4107RF6 penicillin-binding protein BAALB65_12545 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BAALB65_12550 ENOG4105SXS Protein of unknown function (DUF456) BAALB65_12565 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) BAALB65_12570 ENOG41063Y9 BAALB65_12575 ENOG4108U5J '-nucleotidase BAALB65_12580 ENOG4105N80 Ferric uptake regulator, Fur family BAALB65_12585 ENOG4108JYZ YitT family BAALB65_12590 ENOG41069ZM Protein of unknown function (DUF2624) BAALB65_12595 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) BAALB65_12610 ENOG4108IUH Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) BAALB65_12615 ENOG4105EGD dinuclear metal center protein, YbgI family BAALB65_12630 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAALB65_12635 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BAALB65_12640 ENOG4108UPT UPF0178 protein BAALB65_12645 ENOG4105CF9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity) BAALB65_12655 ENOG4105C38 Glycyl-tRNA synthetase beta subunit BAALB65_12660 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit BAALB65_12665 ENOG4106DBE Involved in DNA repair and RecF pathway recombination (By similarity) BAALB65_12675 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BAALB65_12680 ENOG4105KG3 cytidine deaminase BAALB65_12685 ENOG4107YR5 Diacylglycerol kinase BAALB65_12690 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) BAALB65_12695 ENOG4105CTJ Metal Dependent Phosphohydrolase BAALB65_12700 ENOG4105C9A Phoh family BAALB65_12705 ENOG4105EI1 sporulation protein yqfd BAALB65_12710 ENOG41068P3 sporulation protein YqfC BAALB65_12720 ENOG4105DI5 UPF0365 protein BAALB65_12725 ENOG4105F7J membrane-bound serine protease BAALB65_12730 ENOG4105KTH gatB Yqey BAALB65_12745 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BAALB65_12750 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BAALB65_12755 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) BAALB65_12760 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) BAALB65_12765 ENOG4105CFG Acts as a chaperone (By similarity) BAALB65_12770 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ BAALB65_12775 ENOG4105CI8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity) BAALB65_12780 ENOG4105CSA Coproporphyrinogen iii oxidase BAALB65_12785 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) BAALB65_12795 ENOG4108ZRV stage ii sporulation protein p BAALB65_12800 ENOG4105CEF Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity) BAALB65_12805 ENOG4105KQV Binds directly to 16S ribosomal RNA (By similarity) BAALB65_12810 ENOG4105TQK DNA polymerase iii, delta' subunit BAALB65_12820 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BAALB65_12825 ENOG4108UK2 deaminase BAALB65_12830 ENOG4105KQC Competence protein BAALB65_12840 ENOG4108D32 Methyltransferase BAALB65_12850 ENOG4108WF2 Metal Dependent Phosphohydrolase BAALB65_12855 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) BAALB65_12860 ENOG410812S Rna-binding protein BAALB65_12865 ENOG4105E2X shikimate dehydrogenase BAALB65_12870 ENOG4105CQW ribosome biogenesis GTPase YqeH BAALB65_12875 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BAALB65_12895 ENOG41080BT SNARE associated Golgi BAALB65_12915 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAALB65_12940 ENOG4106BHF BAALB65_12960 ENOG41086D8 Transcriptional regulator BAALB65_12980 ENOG4108SWU Histidine kinase BAALB65_12985 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAALB65_12990 ENOG4105DHF Membrane BAALB65_12995 ENOG4108UYN gCN5-related N-acetyltransferase BAALB65_13000 ENOG4105KR8 Inherit from COG: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) BAALB65_13010 ENOG4108J8C transporter major facilitator family protein BAALB65_13020 ENOG4108U7W acetyltransferase BAALB65_13035 ENOG4108HCJ Hydrolase BAALB65_13040 ENOG4108HCJ Hydrolase BAALB65_13050 ENOG4105DG6 mannose-6-phosphate isomerase BAALB65_13055 ENOG4105DM4 PTS System BAALB65_13070 ENOG4108Z66 YbaK ebsC protein BAALB65_13075 ENOG4107RSM transcriptional regulator BAALB65_13080 ENOG4105D94 Major Facilitator Superfamily BAALB65_13085 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BAALB65_13090 ENOG41082JN Transcriptional regulator BAALB65_13110 ENOG4105TMB Formate nitrite transporter BAALB65_13115 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BAALB65_13120 ENOG4108JB9 formate dehydrogenase BAALB65_13135 ENOG4105C28 cystathionine BAALB65_13165 ENOG4107XRG penicillin-binding protein BAALB65_13170 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) BAALB65_13180 ENOG4105CFP Peptidase U32 BAALB65_13185 ENOG4105XYU peptidase (U32 family) BAALB65_13190 ENOG4108VQJ O-methyltransferase BAALB65_13195 ENOG4105HHA aminodeoxychorismate lyase BAALB65_13205 ENOG4108Z08 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) BAALB65_13210 ENOG4105VBH UPF0297 protein BAALB65_13215 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BAALB65_13220 ENOG4105C02 permease BAALB65_13225 ENOG4105CDA abc transporter atp-binding protein BAALB65_13230 ENOG4105CT1 (ABC) transporter BAALB65_13235 ENOG4105EAD ABC transporter BAALB65_13240 ENOG4105DRP amino acid AbC transporter BAALB65_13250 ENOG41060CR BAALB65_13260 ENOG4105C7H Helicase, RecD TraA family BAALB65_13270 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) BAALB65_13275 ENOG4105C3J Cysteine desulfurase BAALB65_13285 ENOG4105D1H recombination factor protein RarA BAALB65_13290 ENOG4105CUZ uba thif-type nad fad binding protein BAALB65_13300 ENOG4105C9M aspartyl-trna synthetase BAALB65_13305 ENOG4105CUT histidyl-tRNA synthetase BAALB65_13310 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BAALB65_13315 ENOG4108YYA Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity) BAALB65_13320 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BAALB65_13330 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BAALB65_13335 ENOG41067VP Protein of unknown function (DUF1049) BAALB65_13340 ENOG4105NCW Trka-c domain protein BAALB65_13345 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BAALB65_13355 ENOG4105CKP Polysaccharide Biosynthesis Protein BAALB65_13360 ENOG4108QG2 Membrane BAALB65_13365 ENOG4105NAP BAALB65_13370 ENOG4105VIE preprotein translocase, subunit YajC BAALB65_13375 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) BAALB65_13380 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) BAALB65_13385 ENOG41061AI Protein of unknown function (DUF2905) BAALB65_13390 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) BAALB65_13395 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) BAALB65_13415 ENOG4106678 morphogenetic protein associated with SpoVID BAALB65_13420 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) BAALB65_13425 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BAALB65_13430 ENOG4108IYU L-aspartate oxidase BAALB65_13445 ENOG4105CQC Prephenate dehydratase BAALB65_13455 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control BAALB65_13465 ENOG4105K46 50S ribosomal protein l27 BAALB65_13470 ENOG4105X36 (ribosomal) protein BAALB65_13475 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) BAALB65_13490 ENOG4107QMS site-determining protein BAALB65_13495 ENOG4107YDG Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) BAALB65_13500 ENOG4105YHC Rod shape-determining protein MreD BAALB65_13505 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BAALB65_13510 ENOG4105DFF Rod shape-determining protein mreb BAALB65_13515 ENOG4105W5Q DNA repair protein (RadC BAALB65_13520 ENOG4108Z03 MAF-like protein BAALB65_13530 ENOG4106A3R peptidase BAALB65_13535 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BAALB65_13540 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BAALB65_13550 ENOG4106AR7 Spore coat protein BAALB65_13555 ENOG41068KH stage VI sporulation protein D BAALB65_13560 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase BAALB65_13565 ENOG4105D52 delta-aminolevulinic acid dehydratase BAALB65_13575 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) BAALB65_13585 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) BAALB65_13595 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) BAALB65_13600 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) BAALB65_13605 ENOG4108IUQ atp-dependent protease BAALB65_13610 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) BAALB65_13615 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation BAALB65_13625 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) BAALB65_13630 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) BAALB65_13635 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BAALB65_13645 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BAALB65_13650 ENOG4108ZP8 Acetolactate synthase small subunit BAALB65_13655 ENOG4105C7K acetolactate synthase BAALB65_13680 ENOG4105M59 Phosphodiesterase, mj0936 family BAALB65_13685 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BAALB65_13690 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) BAALB65_13695 ENOG4108XJQ germination protein BAALB65_13700 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BAALB65_13705 ENOG41067TZ transcriptional regulator, MarR family BAALB65_13710 ENOG4105PFC Transcriptional regulator BAALB65_13720 ENOG4105E33 succinate dehydrogenase BAALB65_13730 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BAALB65_13740 ENOG4105CFH Aspartokinase BAALB65_13750 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BAALB65_13755 ENOG4105K63 Thioredoxin BAALB65_13760 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) BAALB65_13765 ENOG4105C10 Electron transfer flavoprotein BAALB65_13770 ENOG4105BZJ Electron transfer flavoprotein BAALB65_13775 ENOG41060WC Enoyl-CoA hydratase BAALB65_13780 ENOG4107Z3H Transcriptional regulator, TetR family BAALB65_13785 ENOG4105CEY Amp-dependent synthetase and ligase BAALB65_13790 ENOG4108YV3 Protein of unknown function (DUF2711) BAALB65_13800 ENOG4105C98 muts2 protein BAALB65_13805 ENOG4105DCG PHP domain protein BAALB65_13820 ENOG4107FSS Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) BAALB65_13825 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BAALB65_13830 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) BAALB65_13835 ENOG4108RWN rrna methyltransferase BAALB65_13840 ENOG41067MF small acid-soluble spore protein BAALB65_13850 ENOG4105CQB FAD linked oxidase domain protein BAALB65_13855 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BAALB65_13865 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) BAALB65_13870 ENOG4105DRS transport system, permease BAALB65_13885 ENOG4108MDK Dehydrogenase BAALB65_13895 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase BAALB65_13900 ENOG4105EF1 ribulokinase BAALB65_13910 ENOG4107PMW Arabinan endo-1,5-alpha-L-arabinosidase BAALB65_13915 ENOG4105CN9 Peptidase m42 family protein BAALB65_13925 ENOG410696E Membrane BAALB65_13930 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) BAALB65_13935 ENOG4105VJV 50s ribosomal protein L35 BAALB65_13940 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BAALB65_13945 ENOG41067MG lrgb family BAALB65_13955 ENOG4105DY9 regulatoR BAALB65_13960 ENOG4108HRK Histidine kinase BAALB65_13970 ENOG4105U0R haloacid dehalogenase-like hydrolase BAALB65_13975 ENOG4105C22 threonyL-tRNA synthetase BAALB65_13980 ENOG4108TDW sporulation protein YtxC BAALB65_14005 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BAALB65_14010 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BAALB65_14015 ENOG4105KVH Transcriptional regulator BAALB65_14020 ENOG4105F27 Major Facilitator BAALB65_14025 ENOG4105CV8 reductase BAALB65_14030 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BAALB65_14040 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BAALB65_14045 ENOG4105C2M dna polymerase I BAALB65_14050 ENOG4105BZU Histidine kinase BAALB65_14055 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAALB65_14065 ENOG4108HMX isocitrate dehydrogenase (NADP) BAALB65_14070 ENOG4105BZN citrate synthase BAALB65_14085 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BAALB65_14090 ENOG4105G7B Protein of unknown function (DUF2992) BAALB65_14105 ENOG4108REF Sporulation integral membrane protein ytvi BAALB65_14110 ENOG4105FS0 cytoplasmic membrane protein BAALB65_14115 ENOG4105CA9 Pyruvate kinase BAALB65_14120 ENOG4105CTQ phosphohexokinase BAALB65_14125 ENOG4107QM9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity) BAALB65_14130 ENOG4107QTG Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity) BAALB65_14135 ENOG4105C6K Malic enzyme BAALB65_14140 ENOG4105C0B DNA polymerase III (alpha subunit) BAALB65_14145 ENOG4105VV2 BAALB65_14155 ENOG4106EVM BAALB65_14160 ENOG4105SFS phosphoesterase RecJ domain protein BAALB65_14175 ENOG4105E8R UPF0173 metal-dependent hydrolase BAALB65_14185 ENOG4105CH7 arginosuccinase BAALB65_14190 ENOG4105CDH Citrulline--aspartate ligase BAALB65_14195 ENOG4105EPU Molybdenum cofactor synthesis domain protein BAALB65_14200 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BAALB65_14210 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BAALB65_14215 ENOG4105KBJ sporulation protein ytfj BAALB65_14225 ENOG4105VK3 rdd domain containing protein BAALB65_14230 ENOG4105D07 Signal peptide peptidase, SppA BAALB65_14235 ENOG4108KKH Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BAALB65_14240 ENOG4105EFZ amidohydrolase BAALB65_14245 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BAALB65_14255 ENOG4105D8I Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity) BAALB65_14280 ENOG4105U5Y Transcriptional regulator BAALB65_14290 ENOG4105BZU Histidine kinase BAALB65_14300 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) BAALB65_14305 ENOG4105C26 Dehydrogenase BAALB65_14320 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BAALB65_14340 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BAALB65_14355 ENOG4108Z0Z intracellular protease Pfpi family BAALB65_14375 ENOG4108NGU Transcriptional regulator BAALB65_14390 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BAALB65_14405 ENOG4105F1V Acetoin utilization protein BAALB65_14410 ENOG4105W87 Cbs domain BAALB65_14415 ENOG4105DGU Histone deacetylase BAALB65_14420 ENOG4105ER2 Ompa motb domain protein BAALB65_14425 ENOG4107R0U MotA TolQ exbB proton channel BAALB65_14430 ENOG4105ETE Transcriptional regulator (LacI family BAALB65_14435 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BAALB65_14455 ENOG4105DFU Cell wall formation (By similarity) BAALB65_14465 ENOG4108VDD TRNA binding domain protein BAALB65_14480 ENOG4108V0E nucleoside 2-deoxyribosyltransferase YtoQ BAALB65_14495 ENOG4105C6K Malic enzyme BAALB65_14500 ENOG4105C8F Beta-lactamase domain protein BAALB65_14505 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) BAALB65_14515 ENOG4108V15 phosphotransferase enzyme family BAALB65_14530 ENOG4107F58 2'-5' rna ligase BAALB65_14535 ENOG4105C6T cysteine synthase BAALB65_14540 ENOG4107QSE Dipeptidase BAALB65_14545 ENOG4105C7N Xanthine uracil vitamin C permease BAALB65_14560 ENOG4105YW5 deoR family transcriptional regulator BAALB65_14575 ENOG4105CBX hi0933 family BAALB65_14580 ENOG4105C94 Transporter BAALB65_14605 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component BAALB65_14610 ENOG4105I1K ABC transporter BAALB65_14625 ENOG41085GJ domain protein BAALB65_14630 ENOG4105C8T Leucyl-tRNA synthetase BAALB65_14640 ENOG4105BZU Histidine kinase BAALB65_14645 ENOG410605W Major Facilitator BAALB65_14660 ENOG4105C19 ABC transporter BAALB65_14665 ENOG4105EWM Histidine kinase BAALB65_14675 ENOG4107R34 abc transporter permease protein BAALB65_14680 ENOG4105C19 ABC transporter BAALB65_14700 ENOG4105DVE abc transporter atp-binding protein BAALB65_14705 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BAALB65_14715 ENOG4105N5T Radical SAM Protein BAALB65_14730 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BAALB65_14740 ENOG4105E8V Alpha Beta Hydrolase Fold protein BAALB65_14745 ENOG4108Z0R Transferase BAALB65_14750 ENOG4105C85 amino acid BAALB65_14755 ENOG4105CAQ asparagine synthetase BAALB65_14760 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP BAALB65_14765 ENOG4105DJ1 Phosphoenolpyruvate Carboxylase BAALB65_14780 ENOG4105D2X ABC transporter substrate-binding protein BAALB65_14790 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BAALB65_14805 ENOG4108RMU ferritin dps family protein BAALB65_14820 ENOG4106762 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity) BAALB65_14825 ENOG4105VAS Could be involved in insertion of integral membrane proteins into the membrane (By similarity) BAALB65_14830 ENOG4108V2W Carbonate dehydratase BAALB65_14835 ENOG4105NRA 50s ribosomal protein l31 type b BAALB65_14855 ENOG4105CC5 ABC transporter BAALB65_14860 ENOG4105CC5 ABC transporter BAALB65_14865 ENOG4105DIK (ABC) transporter BAALB65_14870 ENOG4105DSE periplasmic solute binding protein BAALB65_14875 ENOG4105DTQ mandelate racemase muconate lactonizing BAALB65_14880 ENOG4105CEY Amp-dependent synthetase and ligase BAALB65_14885 ENOG4108IPT Naphthoate synthase BAALB65_14890 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BAALB65_14895 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) BAALB65_14900 ENOG4105E4F Isochorismate synthase BAALB65_15035 ENOG4105N67 Proton-coupled thiamine transporter YuaJ BAALB65_15040 ENOG4105DZ6 Band 7 protein BAALB65_15050 ENOG4106DF1 BAALB65_15055 ENOG4108VNY MOSC domain protein BAALB65_15060 ENOG4108JB8 alcohol dehydrogenase BAALB65_15065 ENOG4105C26 Dehydrogenase BAALB65_15070 ENOG4105TRT Transcriptional regulator BAALB65_15090 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj BAALB65_15095 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BAALB65_15115 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BAALB65_15125 ENOG4105EE0 oxidoreductase BAALB65_15130 ENOG4108Z0Z intracellular protease Pfpi family BAALB65_15135 ENOG4105C8Q Methyl-accepting chemotaxis BAALB65_15140 ENOG4105C8Q Methyl-accepting chemotaxis BAALB65_15145 ENOG4105C8Q Methyl-accepting chemotaxis BAALB65_15150 ENOG4105C8Q Methyl-accepting chemotaxis BAALB65_15165 ENOG4105EA8 2-Nitropropane dioxygenase BAALB65_15170 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme BAALB65_15180 ENOG4105C37 (CBS) domain BAALB65_15195 ENOG4107PBV potassium channel BAALB65_15200 ENOG4107PBV potassium channel BAALB65_15215 ENOG4107QYV phosphohexose isomerase BAALB65_15230 ENOG4105CHJ isochorismatase hydrolase BAALB65_15240 ENOG4107QW4 alcohol dehydrogenase BAALB65_15245 ENOG4105WG9 Conserved Protein BAALB65_15255 ENOG4105CHM Aminotransferase BAALB65_15260 ENOG4108ZB6 transcriptional regulator AsnC family BAALB65_15265 ENOG4108MUZ hydrolase BAALB65_15275 ENOG4105C87 Aminotransferase class I and II BAALB65_15280 ENOG4108HGU Histidine kinase BAALB65_15285 ENOG4105Y38 Kinase-associated protein B BAALB65_15300 ENOG4105BZ4 penicillin-binding protein BAALB65_15305 ENOG4105KIR Thiol-disulfide oxidoreductase dcc BAALB65_15320 ENOG4108MRH transcriptional regulatory protein BAALB65_15325 ENOG4105DIH basic membrane BAALB65_15330 ENOG4108JQ9 ABC transporter BAALB65_15335 ENOG4105UIB (ABC) transporter BAALB65_15350 ENOG4105D65 subunit l BAALB65_15355 ENOG4105HC0 Na H antiporter BAALB65_15360 ENOG4108ZE9 Monovalent cation H antiporter subunit C BAALB65_15365 ENOG4108JPZ Monovalent cation H antiporter subunit D BAALB65_15370 ENOG4105SC1 monovalent cation H antiporter subunit E BAALB65_15380 ENOG4105KJM monovalent cation h antiporter subunit g BAALB65_15385 ENOG4105KA0 thioesterase Superfamily protein BAALB65_15395 ENOG4105BZU Histidine kinase BAALB65_15430 ENOG4105DAP Nicotinate phosphoribosyltransferase BAALB65_15455 ENOG4105C02 permease BAALB65_15470 ENOG410904N short-chain dehydrogenase reductase BAALB65_15505 ENOG4108K8K Transcriptional regulator BAALB65_15510 ENOG4105DCF alanine dehydrogenase BAALB65_15520 ENOG4105WQT MbtH domain protein BAALB65_15525 ENOG4105CEY Amp-dependent synthetase and ligase BAALB65_15530 ENOG4105WQI isochorismatase BAALB65_15535 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BAALB65_15540 ENOG4105E4F Isochorismate synthase BAALB65_15545 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BAALB65_15550 ENOG4105NIV Esterase BAALB65_15570 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) BAALB65_15580 ENOG41069ER domain protein BAALB65_15595 ENOG4105CEP NADH dehydrogenase BAALB65_15610 ENOG4107SJ1 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity) BAALB65_15625 ENOG4105CJ1 ABC, transporter BAALB65_15650 ENOG4108VHC Short-chain dehydrogenase reductase Sdr BAALB65_15655 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BAALB65_15660 ENOG4105E4Z Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity) BAALB65_15670 ENOG4105ZKE UPF0349 protein BAALB65_15685 ENOG41083MR nifu domain-containing protein BAALB65_15690 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein BAALB65_15695 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) BAALB65_15700 ENOG4108IYI Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity) BAALB65_15705 ENOG4105D6E homoserine dehydrogenase BAALB65_15715 ENOG4108W5N phosphatidylglycerophosphatase a BAALB65_15720 ENOG4105D4U had-superfamily hydrolase, subfamily iia BAALB65_15730 ENOG4105MMD transcriptional regulator BAALB65_15740 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) BAALB65_15745 ENOG4105FAA peptidase M23 BAALB65_15750 ENOG4108YTE sporulation protein YunB BAALB65_15755 ENOG4107R8B 5'-nucleotidase BAALB65_15765 ENOG4105I3N Conserved Protein BAALB65_15775 ENOG4105CD3 dihydroorotase BAALB65_15780 ENOG4105G9B Transcriptional regulator BAALB65_15805 ENOG4105C5R Aminotransferase BAALB65_15815 ENOG4108K8S endonuclease I BAALB65_15820 ENOG4108IJ9 (ABC) transporter BAALB65_15825 ENOG4105FDP GntR family transcriptional regulator BAALB65_15830 ENOG4108KPW sugar kinase BAALB65_15835 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component BAALB65_15840 ENOG4105F0P binding-protein-dependent transport systems inner membrane Component BAALB65_15845 ENOG4105XN3 extracellular solute-binding protein family 1 BAALB65_15850 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine BAALB65_15880 ENOG4105PKS Excinuclease abc c subunit domain protein BAALB65_15885 ENOG4107VFR oxidoreductase BAALB65_15910 ENOG41083Q9 chitosanase BAALB65_15915 ENOG4105DIW FeS assembly protein SUFB BAALB65_15920 ENOG4108UNV SUF system FeS assembly protein, NifU family BAALB65_15925 ENOG4105C9B Cysteine desulfurase BAALB65_15930 ENOG4105JRK feS assembly protein SufD BAALB65_15935 ENOG4105C3K feS assembly ATPase SufC BAALB65_15950 ENOG4105D01 (LipO)protein BAALB65_15955 ENOG4108UMI ABC transporter, permease BAALB65_15960 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BAALB65_15985 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) BAALB65_15990 ENOG41080E8 Transcriptional regulator, Spx MgsR family BAALB65_15995 ENOG4105C1G acyl-Coa dehydrogenase BAALB65_16000 ENOG4105CHU acetyl-coa acetyltransferase BAALB65_16030 ENOG41067TZ transcriptional regulator, MarR family BAALB65_16035 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAALB65_16040 ENOG4105C5Q Transcriptional regulator BAALB65_16060 ENOG4105E0A ABC, transporter BAALB65_16075 ENOG4105E1F short-chain dehydrogenase reductase BAALB65_16080 ENOG4105HUF DNA protection during starvation protein BAALB65_16085 ENOG4105C0H protease BAALB65_16095 ENOG4105F3H Histidine kinase BAALB65_16105 ENOG41067SE Tetr family transcriptional regulator BAALB65_16110 ENOG4105C9Q fumarate hydratase class II BAALB65_16135 ENOG4105WH1 Two component transcriptional regulator luxr family BAALB65_16140 ENOG4105ENE Histidine kinase BAALB65_16155 ENOG41087YS Phage shock protein A BAALB65_16170 ENOG4108WBT adenosyltransferase BAALB65_16175 ENOG4105E0A ABC, transporter BAALB65_16180 ENOG4105EHG Permease protein BAALB65_16185 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) BAALB65_16190 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BAALB65_16195 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein BAALB65_16205 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAALB65_16215 ENOG4106DF4 Sigma-70, region 4 BAALB65_16225 ENOG4105F0F Oxalate decarboxylase BAALB65_16235 ENOG4105E0A ABC, transporter BAALB65_16240 ENOG4105EHG Permease protein BAALB65_16245 ENOG4105DQ5 transport system permease protein BAALB65_16255 ENOG4105JQZ Methyltransferase BAALB65_16260 ENOG4105D5Q Arginine ornithine antiporter BAALB65_16275 ENOG4107K5X Membrane-bound metal-dependent hydrolase BAALB65_16280 ENOG4107QZ2 Sulfatase BAALB65_16285 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BAALB65_16290 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BAALB65_16295 ENOG4105E0C molybdate abc transporter BAALB65_16300 ENOG4105WH1 Two component transcriptional regulator luxr family BAALB65_16305 ENOG4105BZU Histidine kinase BAALB65_16310 ENOG4105CJ1 ABC, transporter BAALB65_16320 ENOG4108KYE ABC-2 type transporter BAALB65_16335 ENOG4105EEQ Na H antiporter BAALB65_16345 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BAALB65_16350 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BAALB65_16355 ENOG4105EEM helicase BAALB65_16360 ENOG4105EN6 Membrane BAALB65_16375 ENOG4107ZQN disulfide bond BAALB65_16380 ENOG4105C59 p-type ATPase BAALB65_16385 ENOG4105C59 p-type ATPase BAALB65_16390 ENOG410681U heavy metal transport detoxification protein BAALB65_16395 ENOG4105VPX protein, conserved in bacteria BAALB65_16400 ENOG4105D9R oxidoreductase BAALB65_16405 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BAALB65_16420 ENOG4105DEN Luciferase family BAALB65_16425 ENOG4105CDA abc transporter atp-binding protein BAALB65_16450 ENOG4108XSB acetyltransferase, (GNAT) family BAALB65_16455 ENOG4108KSA LysR family transcriptional regulator BAALB65_16460 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BAALB65_16465 ENOG41067XF inhibitor BAALB65_16485 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) BAALB65_16490 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BAALB65_16500 ENOG4105XZU Preprotein translocase, subunit SecG BAALB65_16520 ENOG4105KVH Transcriptional regulator BAALB65_16545 ENOG4105DA5 (ABC) transporter BAALB65_16550 ENOG4105R40 Glycine betaine carnitine choline BAALB65_16555 ENOG4108HQR Glycine betaine BAALB65_16560 ENOG4105E90 ABC transporter BAALB65_16565 ENOG4108IJ8 ABC transporter BAALB65_16570 ENOG4107HG4 Transcriptional regulator BAALB65_16575 ENOG4105R40 Glycine betaine carnitine choline BAALB65_16580 ENOG4108HQR Glycine betaine BAALB65_16585 ENOG4105E90 ABC transporter BAALB65_16590 ENOG4108IJ8 ABC transporter BAALB65_16595 ENOG4107HG4 Transcriptional regulator BAALB65_16600 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein BAALB65_16615 ENOG4105T65 Membrane-associated protein BAALB65_16620 ENOG4108W0I acetyltransferase BAALB65_16625 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) BAALB65_16630 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BAALB65_16635 ENOG4105CP7 Triose-phosphate isomerase BAALB65_16640 ENOG4105BZA Phosphoglycerate kinase BAALB65_16650 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BAALB65_16665 ENOG4105CMD Transcriptional regulator, GntR family BAALB65_16670 ENOG4105DEN Luciferase family BAALB65_16675 ENOG4105GZI Transcriptional regulator BAALB65_16680 ENOG4107RT3 EamA-like transporter family BAALB65_16690 ENOG4106KNT transcriptional regulator BAALB65_16695 ENOG4105CMG Carbohydrate kinase BAALB65_16700 ENOG4105C6Z Gluconate BAALB65_16720 ENOG4107QR9 Iron-sulfur cluster binding protein BAALB65_16725 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BAALB65_16730 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BAALB65_16735 ENOG4105JXH GntR family transcriptional regulator BAALB65_16740 ENOG4105DAA L-lactate BAALB65_16745 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAALB65_16755 ENOG4108ZPC Polysaccharide pyruvyl transferase BAALB65_16760 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BAALB65_16765 ENOG4105MME Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family BAALB65_16770 ENOG4105D3Q Sugar transferase BAALB65_16780 ENOG4105K64 Glycosyl transferase, family 2 BAALB65_16790 ENOG4107QRS glycosyltransferase group 2 family protein BAALB65_16795 ENOG41068W6 Capsular polysaccharide biosynthesis protein BAALB65_16800 ENOG4108KMV Glycosyl transferase (Group 1 BAALB65_16805 ENOG4105K64 Glycosyl transferase, family 2 BAALB65_16810 ENOG4108PQP glycosyl transferase group 1 BAALB65_16820 ENOG4108QV3 biosynthesis protein BAALB65_16825 ENOG4105HTX biosynthesis protein BAALB65_16835 ENOG4105EBR Carboxylesterase BAALB65_16845 ENOG4105NAE bifunctional deaminase-reductase domain protein BAALB65_16855 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BAALB65_16865 ENOG4105PY6 Phenolic acid decarboxylase BAALB65_16870 ENOG4105NI3 Protein of unknown function (DUF3237) BAALB65_16900 ENOG4108HKT sucrose-6-phosphate hydrolase BAALB65_16905 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) BAALB65_16910 ENOG4105ETE Transcriptional regulator (LacI family BAALB65_16915 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BAALB65_16920 ENOG4107URF beta-phospho-glucomutase BAALB65_16925 ENOG4105CG3 alpha amylase, catalytic region BAALB65_16940 ENOG4105EG2 ABC transporter, permease BAALB65_16945 ENOG4105D56 permease protein BAALB65_16950 ENOG4107FKK extracellular solute-binding protein family 1 BAALB65_16955 ENOG4108IUK alpha amylase, catalytic BAALB65_16960 ENOG4105FKQ transcriptional regulator BAALB65_16965 ENOG4108URH decarboxylase BAALB65_16970 ENOG4105TPC MazG nucleotide pyrophosphohydrolase domain BAALB65_16975 ENOG4105CHH sulfate transporter BAALB65_16980 ENOG4108V2W Carbonate dehydratase BAALB65_16990 ENOG4105C5I Dehydrogenase BAALB65_16995 ENOG4105GGE ribonuclease BAALB65_17000 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BAALB65_17005 ENOG4105KRI phosphocarrier protein (HPr BAALB65_17010 ENOG4105CIE May be required for sporulation (By similarity) BAALB65_17015 ENOG4105CHW UPF0052 protein BAALB65_17020 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) BAALB65_17025 ENOG4108Z4K mutator MutT protein BAALB65_17030 ENOG4105C3M thioredoxin reductase BAALB65_17045 ENOG4105BZU Histidine kinase BAALB65_17050 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAALB65_17055 ENOG4105GIG BAALB65_17060 ENOG4105BZ1 (ABC) transporter BAALB65_17065 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase BAALB65_17070 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) BAALB65_17075 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase BAALB65_17080 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) BAALB65_17085 ENOG4105ECC imidazole-glycerol-phosphate dehydratase BAALB65_17090 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BAALB65_17095 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) BAALB65_17100 ENOG4108IQ6 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity) BAALB65_17110 ENOG4108S4C acetyltransferase BAALB65_17115 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BAALB65_17125 ENOG4105D1C Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity) BAALB65_17130 ENOG4105CE4 GlcNAc 6-P deacetylase BAALB65_17135 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) BAALB65_17140 ENOG4105FDP GntR family transcriptional regulator BAALB65_17145 ENOG4105J7D transcriptional regulator BAALB65_17150 ENOG41088CQ domain protein BAALB65_17155 ENOG41086DT Membrane protein of unknown function BAALB65_17160 ENOG41067S9 phage shock protein C, PspC BAALB65_17165 ENOG4108PY7 BAALB65_17180 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BAALB65_17185 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BAALB65_17200 ENOG4105MKU Transcriptional regulator BAALB65_17240 ENOG4105CHR reductase BAALB65_17265 ENOG4105CN1 protease BAALB65_17270 ENOG4108M26 parallel beta-helix repeat protein BAALB65_17275 ENOG4105CRP Part of the ABC transporter FtsEX involved in BAALB65_17280 ENOG4105CAK Cell division ATP-binding protein ftsE BAALB65_17300 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving BAALB65_17305 ENOG4105MS2 ribosomal subunit Interface protein BAALB65_17320 ENOG4105MQ3 flagellar protein FliS BAALB65_17325 ENOG4107RT6 flagellar hook-associated BAALB65_17330 ENOG4105I03 Flagellin BAALB65_17335 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) BAALB65_17340 ENOG4105W5T Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity) BAALB65_17350 ENOG4105DTJ flagellar hook-associated protein BAALB65_17355 ENOG4105E1Q flagellar hook-associated protein BAALB65_17370 ENOG4105RU3 BAALB65_17375 ENOG41081UC Inherit from COG: Competence protein BAALB65_17395 ENOG4105WH1 Two component transcriptional regulator luxr family BAALB65_17400 ENOG4105BZU Histidine kinase BAALB65_17405 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BAALB65_17410 ENOG4108KGH TRANSCRIPTIONal BAALB65_17415 ENOG4105ESV Glycosyl transferase, family 4 BAALB65_17420 ENOG4107EF8 Glycosyl transferase (Group 1 BAALB65_17435 ENOG4105QZI O-Antigen Polymerase BAALB65_17440 ENOG4105C6Y Udp-glucose 6-dehydrogenase BAALB65_17445 ENOG4107RA4 Glycosyl transferase (Group 1 BAALB65_17450 ENOG4105PSV Polysaccharide Biosynthesis Protein BAALB65_17455 ENOG4105D3Q Sugar transferase BAALB65_17460 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BAALB65_17465 ENOG4105JFG SpoIID LytB domain protein BAALB65_17475 ENOG4108KGH TRANSCRIPTIONal BAALB65_17480 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BAALB65_17485 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BAALB65_17490 ENOG4105EY8 ABC transporter BAALB65_17505 ENOG4107SJB teichoic acid biosynthesis BAALB65_17510 ENOG4108NMT An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity) BAALB65_17515 ENOG4107ZIC Glycerol-3-phosphate cytidylyltransferase BAALB65_17525 ENOG4107RZX Teichoic acid biosynthesis protein BAALB65_17535 ENOG4105DG6 mannose-6-phosphate isomerase BAALB65_17550 ENOG4108NHD germination protein BAALB65_17555 ENOG4107R8N Glycosyl transferase, family 2 BAALB65_17560 ENOG4105C54 Major Facilitator superfamily BAALB65_17565 ENOG4108KGH TRANSCRIPTIONal BAALB65_17570 ENOG4105J7I hydrolase BAALB65_17575 ENOG4106UBQ BAALB65_17580 ENOG4105K4H Nlp p60 protein BAALB65_17590 ENOG4105PNM synthesis protein BAALB65_17600 ENOG4105N98 Capsule biosynthesis protein capB BAALB65_17610 ENOG4105E1K spore germination protein BAALB65_17625 ENOG4105ETE Transcriptional regulator (LacI family BAALB65_17630 ENOG4108RVA ribokinase BAALB65_17635 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) BAALB65_17640 ENOG4105C2J ABC transporter BAALB65_17645 ENOG4105CNN ABC, transporter BAALB65_17650 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BAALB65_17660 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BAALB65_17665 ENOG4107FQX Alpha-acetolactate decarboxylase BAALB65_17675 ENOG4107RSM transcriptional regulator BAALB65_17690 ENOG4106UIA BAALB65_17705 ENOG4107XC4 flavin reductase domain protein, FMN-binding BAALB65_17715 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) BAALB65_17725 ENOG4105CAH Chromate BAALB65_17730 ENOG4105FGV Chromate BAALB65_17740 ENOG4108WS4 fmn reductase BAALB65_17745 ENOG4107V2S Transcriptional regulator BAALB65_17750 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) BAALB65_17775 ENOG4108XI2 Domain of unknown function (DUF1963) BAALB65_17780 ENOG4105C6Y Udp-glucose 6-dehydrogenase BAALB65_17785 ENOG4108RB3 Capsular polysaccharide biosynthesis protein BAALB65_17790 ENOG4107YJ4 chain length determinant protein BAALB65_17795 ENOG4105HTX biosynthesis protein BAALB65_17810 ENOG4105KBK Zinc finger, swim domain protein BAALB65_17815 ENOG4105C0D helicase BAALB65_17820 ENOG410667J hydrolase BAALB65_17825 ENOG4105E98 transcriptional regulator DeoR family BAALB65_17830 ENOG4105Z8H single-stranded DNA-binding protein BAALB65_17845 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) BAALB65_17850 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) BAALB65_17860 ENOG4105CGA flagellar basal-body rod protein FlgG BAALB65_17870 ENOG4105DFF Rod shape-determining protein mreb BAALB65_17875 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BAALB65_17880 ENOG4107MII Sugar-specific transcriptional regulator TrmB BAALB65_17885 ENOG4105CZM Major Facilitator BAALB65_17890 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease BAALB65_17895 ENOG41080V3 Major Facilitator superfamily BAALB65_17900 ENOG4105D3W isochorismatase BAALB65_17905 ENOG4105BZU Histidine kinase BAALB65_17915 ENOG4105CNI cell division protein FtsW BAALB65_17920 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BAALB65_17930 ENOG4105FRN stage II sporulation protein BAALB65_17935 ENOG4107TCE N-acetyltransferase BAALB65_17950 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BAALB65_17955 ENOG4106BRK BAALB65_17960 ENOG4107T94 Endo-14-beta-xylanase BAALB65_17965 ENOG4108Z40 Transcriptional regulator BAALB65_17970 ENOG4105CQM Urea amidohydrolase subunit alpha BAALB65_17975 ENOG4105KI2 Urea amidohydrolase subunit beta BAALB65_17980 ENOG4108YZ9 Urea amidohydrolase subunit gamma BAALB65_18000 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BAALB65_18005 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BAALB65_18010 ENOG4108TF4 von Willebrand factor, type A BAALB65_18025 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BAALB65_18035 ENOG4106778 Protein of unknown function (DUF1146) BAALB65_18045 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) BAALB65_18050 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) BAALB65_18055 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) BAALB65_18060 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) BAALB65_18065 ENOG4107YZM F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) BAALB65_18080 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BAALB65_18090 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) BAALB65_18095 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) BAALB65_18100 ENOG4108UIC UPF0340 protein BAALB65_18105 ENOG4108YZG isomerase BAALB65_18110 ENOG4107WAU Protein tyrosine phosphatase BAALB65_18115 ENOG410815N Probably functions as a manganese efflux pump (By similarity) BAALB65_18120 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BAALB65_18130 ENOG4108ZXQ stage ii sporulation protein r BAALB65_18145 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BAALB65_18150 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BAALB65_18155 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BAALB65_18165 ENOG4107TT2 Auxin Efflux Carrier BAALB65_18170 ENOG4105C6K Malic enzyme BAALB65_18175 ENOG4107104 thymidine kinase BAALB65_18180 ENOG41082DI 50s ribosomal protein l31 BAALB65_18185 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BAALB65_18190 ENOG4105CBT Fructose-1,6-bisphosphatase BAALB65_18195 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BAALB65_18205 ENOG4105D2N Aldolase BAALB65_18210 ENOG410812K response regulator receiver protein BAALB65_18220 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) BAALB65_18230 ENOG4105DF6 Fe-S oxidoreductase BAALB65_18240 ENOG4105E5J UV damage endonuclease BAALB65_18250 ENOG4105BZ1 (ABC) transporter BAALB65_18255 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BAALB65_18270 ENOG4105R3A Nitrate reductase BAALB65_18275 ENOG4108IUE nitrate reductase beta subunit BAALB65_18295 ENOG4107V6Q Cyclic nucleotide-binding domain BAALB65_18305 ENOG4105C75 arginyL-tRNA synthetase BAALB65_18310 ENOG410684U Domain of unknown function (DUF1934) BAALB65_18315 ENOG4107JM4 Tetratricopeptide repeat BAALB65_18360 ENOG4105CYW agmatinase BAALB65_18365 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BAALB65_18370 ENOG4105BZ4 penicillin-binding protein BAALB65_18380 ENOG4108XFG YwhD family BAALB65_18385 ENOG4108Z4T Peptidase M50 BAALB65_18390 ENOG41069HH 4-oxalocrotonate tautomerase BAALB65_18395 ENOG41067TZ transcriptional regulator, MarR family BAALB65_18405 ENOG4105CUB amino acid BAALB65_18415 ENOG4105DCI Phosphohydrolase BAALB65_18425 ENOG4108VCI transcription factor, rsfa family BAALB65_18430 ENOG4105K7K Transcriptional regulator BAALB65_18440 ENOG4105CJ1 ABC, transporter BAALB65_18445 ENOG4108TU7 Inherit from COG: (ABC) transporter BAALB65_18470 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) BAALB65_18475 ENOG4105DUM transcriptional regulator, lysR family BAALB65_18480 ENOG4105HMI Membrane BAALB65_18485 ENOG4108IJ2 phosphate acetyltransferase BAALB65_18490 ENOG4107JTW chlorite dismutase BAALB65_18500 ENOG4105CHM Aminotransferase BAALB65_18530 ENOG4105FCW Major Facilitator superfamily BAALB65_18535 ENOG4105C2C drug resistance transporter, Bcr CflA BAALB65_18550 ENOG4105C26 Dehydrogenase BAALB65_18555 ENOG4105D82 Glutamate dehydrogenase BAALB65_18565 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAALB65_18585 ENOG4107ZIM Dtdp-4-dehydrorhamnose 3,5-epimerase BAALB65_18590 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BAALB65_18595 ENOG4105C1B dTDP-glucose 4-6-dehydratase BAALB65_18600 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BAALB65_18605 ENOG4107P9E Inherit from COG: pseudaminic acid biosynthesis-associated protein PseG BAALB65_18610 ENOG4107TY6 Acylneuraminate cytidylyltransferase BAALB65_18620 ENOG41067MN Spore coat polysaccharide biosynthesis protein spsD BAALB65_18625 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BAALB65_18660 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) BAALB65_18665 ENOG4108RJ9 Glycosyl transferase, family 2 BAALB65_18685 ENOG4105DWF phosphomethylpyrimidine kinase BAALB65_18700 ENOG4105C5Y PTS System BAALB65_18715 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BAALB65_18720 ENOG4105DEN Luciferase family BAALB65_18730 ENOG4108DBC nitroreductase BAALB65_18740 ENOG4105I4A GCN5-related N-acetyltransferase BAALB65_18760 ENOG4105BZ9 Cytochrome C oxidase, subunit I BAALB65_18765 ENOG4105E2S oxidase) subunit II BAALB65_18770 ENOG4107BMA Transglycosylase associated protein BAALB65_18785 ENOG4105WH5 Teichoic acid glycosylation protein BAALB65_18810 ENOG4107ZXU DSBA oxidoreductase BAALB65_18815 ENOG4105DBE peroxidase BAALB65_18820 ENOG410650H (LipO)protein BAALB65_18825 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) BAALB65_18830 ENOG4105C4U 4-methyl-5-beta-hydroxyethylthiazole kinase BAALB65_18835 ENOG4105CMU LysR family (Transcriptional regulator BAALB65_18840 ENOG4105VAW lrga family BAALB65_18845 ENOG41067MG lrgb family BAALB65_18855 ENOG4107TXC Transcriptional regulator BAALB65_18865 ENOG4105DR4 Methyltransferase BAALB65_18875 ENOG4105CK1 PTS System BAALB65_18880 ENOG4105J8Z peptidase S8 and S53, subtilisin, kexin, sedolisin BAALB65_18885 ENOG4105X1N Glycosyl transferase family 8 BAALB65_18890 ENOG4105GVJ transcriptional regulator BAALB65_18895 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BAALB65_18905 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BAALB65_18920 ENOG4108IQD Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity) BAALB65_18925 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BAALB65_18930 ENOG4105X96 Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity) BAALB65_18935 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BAALB65_18940 ENOG4105CM2 brancheD-chain amino acid aminotransferase BAALB65_18945 ENOG4105F8D glycoside hydrolase family 4 BAALB65_18950 ENOG4105VCP PTS System BAALB65_18955 ENOG4105CK1 PTS System BAALB65_18960 ENOG4105VZJ PTS System BAALB65_18965 ENOG4105EMD TRANSCRIPTIONal BAALB65_18980 ENOG4105DQ5 transport system permease protein BAALB65_18985 ENOG4105EHG Permease protein BAALB65_18995 ENOG41082YX Transcriptional regulator, arsr family BAALB65_19000 ENOG4107R5R arsenical pump membrane protein BAALB65_19005 ENOG4105VZJ PTS System BAALB65_19010 ENOG4105VCP PTS System BAALB65_19015 ENOG4105CK1 PTS System BAALB65_19020 ENOG4105CS2 ec 3.2.1.21 BAALB65_19025 ENOG4105EVU fructokinase BAALB65_19030 ENOG4105DG6 mannose-6-phosphate isomerase BAALB65_19040 ENOG4105CH6 catalase BAALB65_19045 ENOG4107QHE Choloylglycine hydrolase BAALB65_19050 ENOG4105ETS cytosine purines uracil thiamine allantoin BAALB65_19055 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) BAALB65_19060 ENOG4108JJ8 (ABC) transporter BAALB65_19065 ENOG4108JJ9 ABC, transporter BAALB65_19070 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BAALB65_19075 ENOG4105C4M (Ubiquinol oxidase) subunit I BAALB65_19080 ENOG4105D2K citrate carrier protein BAALB65_19085 ENOG4107BJW polysaccharide deacetylase BAALB65_19100 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BAALB65_19110 ENOG4105CMR udp-glucose 4-epimerase BAALB65_19115 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BAALB65_19130 ENOG4105DHI Methyltransferase BAALB65_19155 ENOG4105CH6 catalase BAALB65_19160 ENOG4105D4T Citrate transporter BAALB65_19165 ENOG4108RZ2 Glycoside hydrolase family 16 BAALB65_19175 ENOG4105DEU major facilitator superfamily BAALB65_19180 ENOG4105C1J atp-dependent rna helicase BAALB65_19275 ENOG4108NR7 pectate lyase BAALB65_19285 ENOG4107YZX Universal stress protein BAALB65_19300 ENOG4105M6F mutator MutT protein BAALB65_19305 ENOG4106Z5D Glycoside Hydrolase Family 43 BAALB65_19315 ENOG4105C84 Histidine ammonia-lyase BAALB65_19320 ENOG4105CGP Urocanate hydratase BAALB65_19325 ENOG4105CI2 imidazolone-5-propionate hydrolase BAALB65_19330 ENOG4107W25 arginase agmatinase formiminoglutamase BAALB65_19340 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BAALB65_19345 ENOG4105D9N nucleoside BAALB65_19350 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) BAALB65_19355 ENOG4107RHR regulatoR BAALB65_19360 ENOG410667J hydrolase BAALB65_19390 ENOG4108V5C ABC transporter BAALB65_19425 ENOG4105WZ4 isomerase BAALB65_19430 ENOG4105F0H myo-inositol catabolism protein BAALB65_19435 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) BAALB65_19445 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) BAALB65_19455 ENOG4105EDK PfkB domain protein BAALB65_19465 ENOG4105C26 Dehydrogenase BAALB65_19475 ENOG4105CPC Aldo Keto reductase BAALB65_19480 ENOG4107QNK )-transporter BAALB65_19485 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) BAALB65_19495 ENOG41061TZ Short-chain dehydrogenase reductase Sdr BAALB65_19500 ENOG4108S01 response regulator BAALB65_19505 ENOG4108ZGX Histidine kinase BAALB65_19510 ENOG4105ECK Fatty Acid Desaturase BAALB65_19520 ENOG4105ST3 Transcriptional regulator BAALB65_19525 ENOG4105C26 Dehydrogenase BAALB65_19530 ENOG4108ITS PQQ enzyme repeat BAALB65_19540 ENOG4105WAB arsR family transcriptional regulator BAALB65_19545 ENOG4105F27 Major Facilitator BAALB65_19550 ENOG41085PJ rdd domain containing protein BAALB65_19560 ENOG4105D0M Protease HtpX homolog BAALB65_19570 ENOG4105D3R alkyl hydroperoxide reductase BAALB65_19575 ENOG4108JU3 Alkyl hydroperoxide reductase BAALB65_19590 ENOG4105C85 amino acid BAALB65_19595 ENOG4105DMC D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 BAALB65_19600 ENOG4108XHQ (2Fe-2S)-binding domain protein BAALB65_19620 ENOG4105XRQ Xanthine dehydrogenase accessory factor BAALB65_19645 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) BAALB65_19665 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) BAALB65_19670 ENOG4105CPC Aldo Keto reductase BAALB65_19675 ENOG4105WQG acetyltransferase BAALB65_19685 ENOG41066UZ arginase EC 3.5.3.1 BAALB65_19690 ENOG4108IQI permease BAALB65_19695 ENOG4105C8Y Acetylornithine aminotransferase BAALB65_19700 ENOG4108JUB Transcriptional regulator BAALB65_19710 ENOG4105C5H ABC transporter BAALB65_19725 ENOG4105D06 uba thif-type nad fad binding protein BAALB65_19730 ENOG41062D9 Histidine kinase BAALB65_19745 ENOG4105C0H protease BAALB65_19750 ENOG4105Q2H domain protein BAALB65_19765 ENOG4105BZU Histidine kinase BAALB65_19770 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAALB65_19800 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis BAALB65_19805 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BAALB65_19810 ENOG4105CDU Replicative dna helicase BAALB65_19830 ENOG4105EDW glycosyl transferase, family 39 BAALB65_19835 ENOG4107QPH glycogen) synthase BAALB65_19845 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR BAALB65_19850 ENOG4105CPK Glycosyl transferase (Group 1 BAALB65_19870 ENOG4105BZR domain protein BAALB65_19875 ENOG4108XMW Membrane BAALB65_19890 ENOG4105KVH Transcriptional regulator BAALB65_19895 ENOG4105E2M Manganese-dependent inorganic pyrophosphatase BAALB65_19905 ENOG4108UZ3 Transporter BAALB65_19910 ENOG4105EDQ levansucrase EC 2.4.1.10 BAALB65_19915 ENOG4108HKT sucrose-6-phosphate hydrolase BAALB65_19920 ENOG4107XBN GntR Family Transcriptional Regulator BAALB65_19945 ENOG4108TVJ Nitroreductase BAALB65_19950 ENOG4105FS7 Transcriptional regulator BAALB65_19960 ENOG4108U05 Transcriptional regulator BAALB65_19965 ENOG41082BV acetyltransferase BAALB65_19975 ENOG4107XGZ Hydrolase BAALB65_20020 ENOG4107Y9U Membrane BAALB65_20025 ENOG4105C7Z Conserved Protein BAALB65_20030 ENOG4107FCW Abortive infection protein BAALB65_20040 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BAALB65_20050 ENOG4105CGK Exodeoxyribonuclease III BAALB65_20055 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BAALB65_20065 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) BAALB65_20070 ENOG4108UUM single-stranded DNA-binding protein BAALB65_20075 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) BAALB65_20080 ENOG4105C3G gtp-binding protein BAALB65_20085 ENOG4108J2R molybdopterin oxidoreductase BAALB65_20090 ENOG4105VDK protein, conserved in bacteria BAALB65_20105 ENOG4108ZDA Sporulation protein YyaC BAALB65_20110 ENOG4105FA0 parb-like partition protein BAALB65_20115 ENOG4107QJE Chromosome Partitioning Protein BAALB65_20130 ENOG4105CWE NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) BAALB65_20135 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) BAALB65_20150 ENOG4105M7T RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)