locus-tag	class	description
DDT09_00010	COG0592	DNA-directed DNA polymerase activity
DDT09_00015	COG2501	S4 domain
DDT09_00030	COG0187	DNA topoisomerase II activity
DDT09_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DDT09_00070	COG0517	IMP dehydrogenase activity
DDT09_00070	COG0516	GMP reductase activity
DDT09_00075	COG1686	Belongs to the peptidase S11 family
DDT09_00095	COG1929	Belongs to the glycerate kinase type-1 family
DDT09_00105	COG1428	Deoxynucleoside kinase
DDT09_00110	COG1428	Deoxynucleoside kinase
DDT09_00115	COG1388	LysM domain
DDT09_00115	COG3858	chitin binding
DDT09_00120	COG1335	isochorismatase
DDT09_00125	COG0590	tRNA wobble adenosine to inosine editing
DDT09_00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DDT09_00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DDT09_00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
DDT09_00195	COG3853	Toxic anion resistance protein (TelA)
DDT09_00200	COG1982	Orn Lys Arg decarboxylase major
DDT09_00210	COG3870	Protein conserved in bacteria
DDT09_00215	COG1728	Protein conserved in bacteria
DDT09_00220	COG0470	DNA polymerase III
DDT09_00225	COG1774	PSP1 C-terminal conserved region
DDT09_00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DDT09_00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DDT09_00250	COG2002	toxin-antitoxin pair type II binding
DDT09_00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DDT09_00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DDT09_00260	COG0084	hydrolase, TatD family'
DDT09_00265	COG3584	3D domain protein
DDT09_00265	COG3583	domain protein
DDT09_00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DDT09_00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DDT09_00285	COG4466	Protein conserved in bacteria
DDT09_00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DDT09_00305	COG0251	oxidation-reduction process
DDT09_00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DDT09_00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DDT09_00345	COG2002	toxin-antitoxin pair type II binding
DDT09_00350	COG2244	polysaccharide biosynthetic process
DDT09_00355	COG3956	TIGRFAM MazG family protein
DDT09_00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DDT09_00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DDT09_00380	COG1098	S1 RNA binding domain
DDT09_00395	COG2208	phosphoserine phosphatase activity
DDT09_00400	COG2304	oxidoreductase activity
DDT09_00405	COG0515	serine threonine protein kinase
DDT09_00410	COG0037	tRNA processing
DDT09_00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DDT09_00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DDT09_00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DDT09_00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DDT09_00450	COG0512	Glutamine amidotransferase of anthranilate synthase
DDT09_00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DDT09_00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DDT09_00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DDT09_00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DDT09_00475	COG1396	sequence-specific DNA binding
DDT09_00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DDT09_00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DDT09_00565	COG4463	regulation of RNA biosynthetic process
DDT09_00570	COG3880	PFAM UvrB UvrC protein
DDT09_00580	COG0542	response to heat
DDT09_00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DDT09_00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DDT09_00595	COG4956	integral membrane protein (PIN domain superfamily)
DDT09_00615	COG1045	serine acetyltransferase
DDT09_00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DDT09_00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DDT09_00635	COG3688	RNA-binding protein containing a PIN domain
DDT09_00640	COG1595	DNA-templated transcription, initiation
DDT09_00645	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DDT09_00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DDT09_00655	COG0250	Participates in transcription elongation, termination and antitermination
DDT09_00660	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DDT09_00675	COG0222	ribosome binding
DDT09_00680	COG2813	Specifically methylates the guanine in position
DDT09_00695	COG1358	cellular component organization or biogenesis
DDT09_00720	COG0596	Alpha beta hydrolase
DDT09_00725	COG0051	transcription antitermination factor activity, RNA binding
DDT09_00740	COG0089	rRNA binding
DDT09_00750	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DDT09_00755	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DDT09_00765	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DDT09_00770	COG0255	Belongs to the universal ribosomal protein uL29 family
DDT09_00820	COG1841	ribosomal large subunit assembly
DDT09_00830	COG0201	protein transport
DDT09_00840	COG0024	Methionine aminopeptidase
DDT09_00850	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DDT09_00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DDT09_00880	COG1122	ATPase activity
DDT09_00885	COG1122	ATPase activity
DDT09_00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DDT09_00910	COG2226	methyltransferase
DDT09_00915	COG2318	DinB family
DDT09_00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
DDT09_00930	COG0489	protein tyrosine kinase activity
DDT09_00940	COG2194	sulfuric ester hydrolase activity
DDT09_00945	COG0726	polysaccharide deacetylase
DDT09_01005	COG0738	Major facilitator superfamily
DDT09_01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DDT09_01025	COG0659	secondary active sulfate transmembrane transporter activity
DDT09_01030	COG0385	Bile acid
DDT09_01035	COG2819	hydrolase of the alpha beta superfamily
DDT09_01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDT09_01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDT09_01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DDT09_01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DDT09_01055	COG2207	Transcriptional regulator
DDT09_01060	COG3876	Protein conserved in bacteria
DDT09_01065	COG1472	Belongs to the glycosyl hydrolase 3 family
DDT09_01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DDT09_01075	COG1263	PTS System
DDT09_01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDT09_01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DDT09_01090	COG1683	Conserved Protein
DDT09_01120	COG1595	DNA-templated transcription, initiation
DDT09_01125	COG5662	AntiSigma factor
DDT09_01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DDT09_01135	COG4856	YbbR-like protein
DDT09_01175	COG1346	cytolysis
DDT09_01180	COG1380	Effector of murein hydrolase LrgA
DDT09_01185	COG1846	Transcriptional regulator
DDT09_01190	COG1113	amino acid transport
DDT09_01195	COG1011	Hydrolase
DDT09_01200	COG4585	Histidine kinase
DDT09_01205	COG2197	response regulator
DDT09_01210	COG1131	(ABC) transporter
DDT09_01250	COG0531	amino acid
DDT09_01255	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
DDT09_01270	COG0584	glycerophosphoryl diester phosphodiesterase
DDT09_01275	COG2271	Major facilitator Superfamily
DDT09_01290	COG2368	4-hydroxyphenylacetate
DDT09_01300	COG3409	Peptidoglycan-binding domain 1 protein
DDT09_01315	COG0371	Dehydrogenase
DDT09_01325	COG1183	phosphatidylcholine synthase activity
DDT09_01330	COG0586	Pfam SNARE associated Golgi protein
DDT09_01335	COG0688	phosphatidylethanolamine metabolic process
DDT09_01350	COG1301	dicarboxylic acid transport
DDT09_01355	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DDT09_01360	COG0833	amino acid
DDT09_01365	COG2040	homocysteine
DDT09_01370	COG1115	amino acid carrier protein
DDT09_01375	COG2066	Belongs to the glutaminase family
DDT09_01380	COG4191	Histidine kinase
DDT09_01385	COG0784	Response regulator, receiver
DDT09_01390	COG3173	Aminoglycoside phosphotransferase
DDT09_01410	COG3773	Cell wall hydrolase
DDT09_01420	COG3540	Alkaline phosphatase
DDT09_01425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DDT09_01430	COG0805	protein transport
DDT09_01440	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DDT09_01445	COG0477	Major facilitator Superfamily
DDT09_01450	COG1309	transcriptional regulator
DDT09_01455	COG0252	asparaginase activity
DDT09_01460	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DDT09_01465	COG3012	SEC-C Motif Domain Protein
DDT09_01465	COG1405	negative regulation of cell septum assembly
DDT09_01470	COG0667	Aldo Keto reductase
DDT09_01480	COG1595	DNA-templated transcription, initiation
DDT09_01485	COG1595	DNA-templated transcription, initiation
DDT09_01490	COG1876	peptidase activity
DDT09_01495	COG0457	Tetratricopeptide repeat
DDT09_01500	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_01515	COG0366	Alpha amylase catalytic
DDT09_01520	COG0803	Belongs to the bacterial solute-binding protein 9 family
DDT09_01525	COG1121	(ABC) transporter
DDT09_01530	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DDT09_01535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDT09_01540	COG2310	stress, protein
DDT09_01545	COG2310	stress, protein
DDT09_01550	COG2310	stress, protein
DDT09_01555	COG0861	Integral membrane protein TerC family
DDT09_01565	COG3853	Toxic anion resistance protein (TelA)
DDT09_01570	COG0477	Major facilitator Superfamily
DDT09_01575	COG4175	Glycine betaine
DDT09_01575	COG0517	IMP dehydrogenase activity
DDT09_01580	COG4176	ABC-type proline glycine betaine transport system permease component
DDT09_01585	COG2113	Glycine betaine
DDT09_01590	COG1473	amidohydrolase
DDT09_01595	COG1288	antiporter activity
DDT09_01605	COG0366	Alpha amylase catalytic
DDT09_01620	COG2814	Major facilitator Superfamily
DDT09_01625	COG1846	Transcriptional regulator
DDT09_01630	COG1280	lysine exporter protein (LysE YggA)
DDT09_01635	COG3403	YqcI/YcgG family
DDT09_01640	COG1113	amino acid transport
DDT09_01645	COG3665	Urea carboxylase-associated protein
DDT09_01660	COG1660	Displays ATPase and GTPase activities
DDT09_01670	COG2271	Major facilitator Superfamily
DDT09_01675	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DDT09_01680	COG3458	cephalosporin-C deacetylase activity
DDT09_01685	COG3541	Predicted nucleotidyltransferase
DDT09_01690	COG0506	proline dehydrogenase activity
DDT09_01695	COG1012	belongs to the aldehyde dehydrogenase family
DDT09_01700	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DDT09_01705	COG2508	Transcriptional regulator
DDT09_01715	COG1587	Uroporphyrinogen-III synthase
DDT09_01715	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DDT09_01720	COG2146	nitrite reductase [NAD(P)H] activity
DDT09_01725	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DDT09_01730	COG0243	molybdopterin cofactor binding
DDT09_01735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DDT09_01740	COG2223	nitrite transmembrane transporter activity
DDT09_01745	COG0523	cobalamin synthesis protein
DDT09_01750	COG1063	alcohol dehydrogenase
DDT09_01755	COG1714	RDD family
DDT09_01765	COG2723	6-phospho-beta-galactosidase activity
DDT09_01775	COG3209	COG3209 Rhs family protein
DDT09_01780	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DDT09_01785	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
DDT09_01790	COG1733	regulation of RNA biosynthetic process
DDT09_01800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDT09_01805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDT09_01810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDT09_01815	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
DDT09_01830	COG2364	Membrane
DDT09_01835	COG1126	abc transporter atp-binding protein
DDT09_01840	COG0765	amino acid transport
DDT09_01845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDT09_01850	COG0583	DNA-binding transcription factor activity
DDT09_01855	COG0163	prenyltransferase activity
DDT09_01860	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DDT09_01875	COG3104	oligopeptide transport
DDT09_01880	COG5434	Belongs to the glycosyl hydrolase 28 family
DDT09_01890	COG0697	spore germination
DDT09_01900	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DDT09_01915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDT09_01920	COG0765	amino acid transport
DDT09_01925	COG1126	abc transporter atp-binding protein
DDT09_01935	COG2079	MmgE PrpD family protein
DDT09_01940	COG1136	(ABC) transporter
DDT09_01945	COG0577	efflux transmembrane transporter activity
DDT09_01950	COG0745	RESPONSE REGULATOR receiver
DDT09_01955	COG3850	Histidine kinase
DDT09_01955	COG5002	protein histidine kinase activity
DDT09_01960	COG0457	Tetratricopeptide repeat
DDT09_01975	COG0527	aspartate kinase activity
DDT09_01980	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDT09_01985	COG4605	iron ion homeostasis
DDT09_01990	COG4604	ABC transporter, ATP-binding protein
DDT09_01995	COG4607	ABC-type enterochelin transport system periplasmic component
DDT09_02000	COG2814	Major facilitator Superfamily
DDT09_02005	COG1309	transcriptional regulator
DDT09_02010	COG0778	Nitroreductase
DDT09_02015	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DDT09_02020	COG0640	Transcriptional regulator
DDT09_02025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDT09_02030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DDT09_02035	COG1012	belongs to the aldehyde dehydrogenase family
DDT09_02040	COG4975	Glucose uptake
DDT09_02045	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_02050	COG4549	nuclear export factor GLE1
DDT09_02055	COG1276	copper resistance
DDT09_02055	COG2372	response to copper ion
DDT09_02060	COG1349	DNA-binding transcription factor activity
DDT09_02070	COG2213	PTS system mannitol-specific
DDT09_02075	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDT09_02085	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DDT09_02095	COG0561	phosphatase activity
DDT09_02105	COG1914	H( )-stimulated, divalent metal cation uptake system
DDT09_02115	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DDT09_02120	COG1984	allophanate hydrolase subunit 2
DDT09_02125	COG1414	Transcriptional regulator
DDT09_02130	COG2755	lipolytic protein G-D-S-L family
DDT09_02140	COG2329	Antibiotic biosynthesis monooxygenase
DDT09_02145	COG0768	penicillin binding
DDT09_02150	COG4989	oxidoreductase activity
DDT09_02155	COG3711	transcriptional antiterminator
DDT09_02160	COG0318	PFAM AMP-dependent synthetase and ligase
DDT09_02165	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_02170	COG1917	Cupin 2, conserved barrel domain protein
DDT09_02175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DDT09_02180	COG3871	stress protein (general stress protein 26)
DDT09_02190	COG2814	Major facilitator Superfamily
DDT09_02195	COG1522	sequence-specific DNA binding
DDT09_02200	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DDT09_02200	COG0551	DNA topoisomerase type I activity
DDT09_02205	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
DDT09_02210	COG3706	GGDEF domain
DDT09_02215	COG5298	Protein conserved in bacteria
DDT09_02220	COG1215	transferase activity, transferring glycosyl groups
DDT09_02230	COG0531	amino acid
DDT09_02235	COG0494	nUDIX hydrolase
DDT09_02240	COG0028	Belongs to the TPP enzyme family
DDT09_02260	COG4282	regulation of fungal-type cell wall biogenesis
DDT09_02270	COG0457	Tetratricopeptide repeat
DDT09_02300	COG1914	H( )-stimulated, divalent metal cation uptake system
DDT09_02315	COG4876	unkown
DDT09_02325	COG2076	Multidrug Resistance protein
DDT09_02330	COG2217	Heavy metal translocating P-type atpase
DDT09_02335	COG3729	General stress protein
DDT09_02340	COG0662	Cupin 2, conserved barrel domain protein
DDT09_02345	COG2329	Antibiotic biosynthesis monooxygenase
DDT09_02350	COG3546	catalase activity
DDT09_02355	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DDT09_02360	COG3290	protein histidine kinase activity
DDT09_02365	COG4565	transcriptional regulatory protein
DDT09_02370	COG1301	dicarboxylic acid transport
DDT09_02375	COG0628	permease
DDT09_02380	COG1131	(ABC) transporter
DDT09_02385	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DDT09_02395	COG1960	acyl-CoA dehydrogenase activity
DDT09_02410	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DDT09_02415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DDT09_02425	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DDT09_02430	COG0513	Belongs to the DEAD box helicase family
DDT09_02435	COG3402	PFAM membrane-flanked domain
DDT09_02440	COG3428	Bacterial PH domain
DDT09_02445	COG0705	Rhomboid family
DDT09_02455	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DDT09_02460	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DDT09_02465	COG0864	Transcriptional regulator
DDT09_02470	COG2337	Toxic component of a toxin-antitoxin (TA) module
DDT09_02475	COG1366	Belongs to the anti-sigma-factor antagonist family
DDT09_02480	COG1366	Belongs to the anti-sigma-factor antagonist family
DDT09_02485	COG2172	sigma factor antagonist activity
DDT09_02490	COG2208	phosphoserine phosphatase activity
DDT09_02495	COG1366	Belongs to the anti-sigma-factor antagonist family
DDT09_02505	COG1191	sigma factor activity
DDT09_02510	COG2208	phosphoserine phosphatase activity
DDT09_02515	COG2183	response to ionizing radiation
DDT09_02565	COG2249	NAD(P)H dehydrogenase (quinone) activity
DDT09_02580	COG0477	Major facilitator Superfamily
DDT09_02585	COG1846	Transcriptional regulator
DDT09_02595	COG2030	dehydratase
DDT09_02610	COG1959	2 iron, 2 sulfur cluster binding
DDT09_02615	COG2910	NAD(P)H-binding
DDT09_02625	COG1309	transcriptional regulator
DDT09_02630	COG3239	Fatty acid desaturase
DDT09_02640	COG1278	Cold shock
DDT09_02645	COG1329	Transcriptional regulator
DDT09_02650	COG1794	racemase activity, acting on amino acids and derivatives
DDT09_02665	COG0456	acetyltransferase
DDT09_02665	COG1846	Transcriptional regulator
DDT09_02670	COG2271	Major facilitator Superfamily
DDT09_02675	COG3621	Patatin-like phospholipase
DDT09_02685	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DDT09_02695	COG0251	oxidation-reduction process
DDT09_02700	COG0814	amino acid
DDT09_02705	COG1473	amidohydrolase
DDT09_02710	COG1917	Cupin 2, conserved barrel domain protein
DDT09_02710	COG2207	Transcriptional regulator
DDT09_02720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDT09_02725	COG0477	Major facilitator Superfamily
DDT09_02745	COG0277	FAD linked oxidase domain protein
DDT09_02775	COG2318	DinB family
DDT09_02780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DDT09_02800	COG1064	alcohol dehydrogenase
DDT09_02805	COG0789	Transcriptional regulator
DDT09_02815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDT09_02830	COG2814	Major facilitator Superfamily
DDT09_02835	COG1309	transcriptional regulator
DDT09_02840	COG0697	spore germination
DDT09_02845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDT09_02850	COG5577	PFAM Coat F domain
DDT09_02860	COG1063	alcohol dehydrogenase
DDT09_02865	COG5577	PFAM Coat F domain
DDT09_02880	COG4585	Histidine kinase
DDT09_02885	COG2197	response regulator
DDT09_02890	COG2409	Drug exporters of the RND superfamily
DDT09_02895	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DDT09_02905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DDT09_02910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DDT09_02920	COG2814	Major facilitator Superfamily
DDT09_02925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DDT09_02935	COG0730	response to heat
DDT09_02940	COG0456	acetyltransferase
DDT09_02945	COG0789	Transcriptional regulator
DDT09_02945	COG4978	Transcriptional regulator
DDT09_02950	COG0697	spore germination
DDT09_02955	COG1051	belongs to the nudix hydrolase family
DDT09_02960	COG2226	methyltransferase
DDT09_02965	COG0473	3-isopropylmalate dehydrogenase activity
DDT09_02970	COG1802	Transcriptional regulator
DDT09_02975	COG1819	glycosyl
DDT09_02990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DDT09_02995	COG1388	LysM domain
DDT09_03000	COG2814	Major facilitator Superfamily
DDT09_03005	COG2188	Transcriptional regulator
DDT09_03010	COG2186	Transcriptional regulator
DDT09_03015	COG2807	transmembrane transport
DDT09_03020	COG2076	Multidrug Resistance protein
DDT09_03025	COG2076	Multidrug Resistance protein
DDT09_03030	COG1309	transcriptional regulator
DDT09_03035	COG0531	amino acid
DDT09_03045	COG3832	glyoxalase III activity
DDT09_03050	COG0604	alcohol dehydrogenase
DDT09_03055	COG2814	Major facilitator Superfamily
DDT09_03095	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DDT09_03100	COG0802	atpase or kinase
DDT09_03105	COG1214	PFAM Peptidase M22, glycoprotease
DDT09_03110	COG0456	acetyltransferase
DDT09_03115	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DDT09_03120	COG0488	(ABC) transporter
DDT09_03135	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DDT09_03140	COG0805	protein transport
DDT09_03150	COG1266	CAAX protease self-immunity
DDT09_03155	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DDT09_03175	COG0457	Tetratricopeptide repeat
DDT09_03180	COG1063	alcohol dehydrogenase
DDT09_03185	COG2211	Major facilitator Superfamily
DDT09_03190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDT09_03200	COG1842	Phage shock protein A
DDT09_03205	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DDT09_03210	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DDT09_03215	COG4260	virion core protein, lumpy skin disease virus
DDT09_03220	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DDT09_03220	COG2755	lipolytic protein G-D-S-L family
DDT09_03230	COG1595	DNA-templated transcription, initiation
DDT09_03235	COG1063	alcohol dehydrogenase
DDT09_03240	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DDT09_03245	COG0823	Involved in the tonB-independent uptake of proteins
DDT09_03255	COG2132	Multicopper oxidase
DDT09_03260	COG1113	amino acid transport
DDT09_03265	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DDT09_03270	COG0714	Associated with various cellular activities
DDT09_03275	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
DDT09_03280	COG1305	Transglutaminase-like
DDT09_03310	COG2211	Major facilitator Superfamily
DDT09_03325	COG2252	PERMEase
DDT09_03330	COG3064	Membrane
DDT09_03350	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DDT09_03355	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DDT09_03360	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DDT09_03365	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DDT09_03370	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DDT09_03385	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DDT09_03395	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DDT09_03400	COG0138	bifunctional purine biosynthesis protein purh
DDT09_03405	COG0151	Belongs to the GarS family
DDT09_03415	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DDT09_03420	COG1470	cell adhesion involved in biofilm formation
DDT09_03425	COG4496	protein, YerC YecD
DDT09_03430	COG0069	glutamate synthase activity
DDT09_03445	COG0210	DNA helicase
DDT09_03455	COG4851	CamS sex pheromone cAM373 precursor
DDT09_03460	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DDT09_03465	COG1285	pathogenesis
DDT09_03470	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DDT09_03490	COG1309	transcriptional regulator
DDT09_03495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DDT09_03500	COG1597	lipid kinase activity
DDT09_03505	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DDT09_03510	COG1136	(ABC) transporter
DDT09_03520	COG1131	(ABC) transporter
DDT09_03550	COG5444	nuclease activity
DDT09_03580	COG3546	catalase activity
DDT09_03585	COG0454	-acetyltransferase
DDT09_03595	COG2323	membrane
DDT09_03600	COG2329	Antibiotic biosynthesis monooxygenase
DDT09_03605	COG0346	lactoylglutathione lyase activity
DDT09_03615	COG1366	Belongs to the anti-sigma-factor antagonist family
DDT09_03620	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DDT09_03625	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DDT09_03630	COG4208	sulfate ABC transporter
DDT09_03640	COG5583	Uncharacterized small protein (DUF2292)
DDT09_03645	COG0196	riboflavin kinase activity
DDT09_03650	COG0670	Belongs to the BI1 family
DDT09_03655	COG1846	Transcriptional regulator
DDT09_03660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DDT09_03670	COG2124	cytochrome p450
DDT09_03670	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DDT09_03685	COG1131	(ABC) transporter
DDT09_03700	COG1368	sulfuric ester hydrolase activity
DDT09_03705	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DDT09_03710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DDT09_03715	COG1442	glycosyl transferase family 8
DDT09_03720	COG1216	Glycosyl transferase, family 2
DDT09_03725	COG1442	glycosyl transferase family 8
DDT09_03730	COG2223	nitrite transmembrane transporter activity
DDT09_03735	COG0531	amino acid
DDT09_03740	COG1012	belongs to the aldehyde dehydrogenase family
DDT09_03745	COG0840	transmembrane signaling receptor activity
DDT09_03750	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_03755	COG0463	Glycosyl transferase, family 2
DDT09_03755	COG0457	Tetratricopeptide repeat
DDT09_03760	COG0488	(ABC) transporter
DDT09_03765	COG0789	Transcriptional regulator
DDT09_03770	COG2814	Major facilitator Superfamily
DDT09_03775	COG0488	(ABC) transporter
DDT09_03780	COG0513	Belongs to the DEAD box helicase family
DDT09_03790	COG2130	NADP-dependent
DDT09_03805	COG3866	Pectate lyase
DDT09_03810	COG0471	metal ion transport
DDT09_03830	COG2972	Histidine kinase
DDT09_03830	COG0745	RESPONSE REGULATOR receiver
DDT09_03845	COG3764	Sortase (surface protein transpeptidase)
DDT09_03850	COG3290	protein histidine kinase activity
DDT09_03855	COG4565	transcriptional regulatory protein
DDT09_03860	COG3181	Tripartite tricarboxylate transporter family receptor
DDT09_03865	COG2851	Citrate transporter
DDT09_03870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DDT09_03875	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
DDT09_03885	COG2258	MOSC domain
DDT09_03905	COG0024	Methionine aminopeptidase
DDT09_03910	COG1263	PTS System
DDT09_03910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDT09_03920	COG1368	sulfuric ester hydrolase activity
DDT09_03930	COG0071	Belongs to the small heat shock protein (HSP20) family
DDT09_03945	COG1263	PTS System
DDT09_03945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDT09_03950	COG0366	Alpha amylase catalytic
DDT09_03955	COG2188	Transcriptional regulator
DDT09_03960	COG0778	Nitroreductase
DDT09_03975	COG0737	Belongs to the 5'-nucleotidase family
DDT09_03980	COG0693	protein deglycase activity
DDT09_03985	COG1609	Transcriptional regulator
DDT09_03990	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DDT09_04000	COG2814	Major facilitator Superfamily
DDT09_04010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DDT09_04015	COG4980	gas vesicle protein
DDT09_04020	COG1295	ribonuclease BN
DDT09_04025	COG0477	Major facilitator Superfamily
DDT09_04030	COG0387	Pfam Sodium calcium exchanger
DDT09_04040	COG0668	transmembrane transport
DDT09_04045	COG0535	radical SAM domain protein
DDT09_04055	COG0726	polysaccharide deacetylase
DDT09_04060	COG2084	Dehydrogenase
DDT09_04070	COG0598	Magnesium transport protein CorA
DDT09_04075	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DDT09_04080	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DDT09_04100	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DDT09_04105	COG4637	Psort location Cytoplasmic, score
DDT09_04110	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DDT09_04115	COG0022	dehydrogenase e1 component
DDT09_04120	COG0508	dehydrogenase complex catalyzes the overall conversion of
DDT09_04125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DDT09_04130	COG3284	Transcriptional regulator
DDT09_04140	COG1486	melibiose metabolic process
DDT09_04145	COG1737	Transcriptional regulator
DDT09_04150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDT09_04150	COG1263	PTS System
DDT09_04155	COG1132	(ABC) transporter
DDT09_04160	COG1132	(ABC) transporter
DDT09_04165	COG2259	Doxx family
DDT09_04170	COG2514	catechol 2,3-dioxygenase activity
DDT09_04185	COG1695	Transcriptional regulator
DDT09_04190	COG2249	NAD(P)H dehydrogenase (quinone) activity
DDT09_04195	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
DDT09_04200	COG0574	Belongs to the PEP-utilizing enzyme family
DDT09_04200	COG3848	Pyruvate phosphate dikinase
DDT09_04205	COG2732	(Barnase) inhibitor
DDT09_04210	COG2318	DinB family
DDT09_04215	COG2814	Major facilitator Superfamily
DDT09_04220	COG1846	Transcriptional regulator
DDT09_04225	COG0392	lysyltransferase activity
DDT09_04225	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DDT09_04230	COG0384	phenazine biosynthesis protein PhzF
DDT09_04235	COG0778	Nitroreductase
DDT09_04250	COG1090	epimerase
DDT09_04265	COG2814	Major facilitator Superfamily
DDT09_04275	COG3591	Belongs to the peptidase S1B family
DDT09_04290	COG3103	Sh3 type 3 domain protein
DDT09_04295	COG5658	integral membrane protein
DDT09_04300	COG0596	Alpha beta hydrolase
DDT09_04305	COG0463	Glycosyl transferase, family 2
DDT09_04310	COG4485	Bacterial membrane protein, YfhO
DDT09_04315	COG1988	membrane-bound metal-dependent
DDT09_04320	COG1194	a g-specific adenine glycosylase
DDT09_04330	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_04350	COG1132	(ABC) transporter
DDT09_04355	COG4129	membrane
DDT09_04370	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DDT09_04375	COG0735	belongs to the Fur family
DDT09_04485	COG1757	Na H antiporter
DDT09_04490	COG3340	Belongs to the peptidase S51 family
DDT09_04500	COG0277	FAD linked oxidase domain protein
DDT09_04510	COG0747	negative chemotaxis
DDT09_04515	COG0601	transmembrane transport
DDT09_04520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DDT09_04525	COG0444	Belongs to the ABC transporter superfamily
DDT09_04530	COG4608	Belongs to the ABC transporter superfamily
DDT09_04535	COG0753	catalase activity
DDT09_04545	COG1116	anion transmembrane transporter activity
DDT09_04550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DDT09_04555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DDT09_04575	COG1476	TRANSCRIPTIONal
DDT09_04585	COG3382	B3 4 domain protein
DDT09_04590	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DDT09_04600	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DDT09_04605	COG0789	Transcriptional regulator
DDT09_04615	COG1664	Polymer-forming cytoskeletal
DDT09_04625	COG2766	serine protein kinase
DDT09_04640	COG1846	Transcriptional regulator
DDT09_04645	COG1566	PFAM secretion protein HlyD family protein
DDT09_04650	COG2814	Major facilitator Superfamily
DDT09_04655	COG0655	NAD(P)H dehydrogenase (quinone) activity
DDT09_04670	COG1725	Transcriptional regulator
DDT09_04675	COG1131	(ABC) transporter
DDT09_04680	COG1131	(ABC) transporter
DDT09_04685	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DDT09_04690	COG1278	Cold shock
DDT09_04700	COG1464	Belongs to the NlpA lipoprotein family
DDT09_04705	COG3706	GGDEF domain
DDT09_04710	COG1823	symporter activity
DDT09_04730	COG5577	PFAM Coat F domain
DDT09_04735	COG1525	nuclease
DDT09_04735	COG4085	toxin activity
DDT09_04735	COG0737	Belongs to the 5'-nucleotidase family
DDT09_04740	COG3764	Sortase (surface protein transpeptidase)
DDT09_04745	COG0564	pseudouridine synthase activity
DDT09_04755	COG0517	IMP dehydrogenase activity
DDT09_04760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DDT09_04765	COG3153	acetyltransferase
DDT09_04765	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DDT09_04770	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DDT09_04775	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DDT09_04780	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DDT09_04790	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DDT09_04795	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DDT09_04800	COG4585	Histidine kinase
DDT09_04800	COG2203	Gaf domain
DDT09_04805	COG2197	response regulator
DDT09_04810	COG0431	NADPH-dependent FMN reductase
DDT09_04825	COG0791	NLP P60 protein
DDT09_04825	COG1388	LysM domain
DDT09_04830	COG1959	2 iron, 2 sulfur cluster binding
DDT09_04835	COG0668	transmembrane transport
DDT09_04840	COG2719	SpoVR family
DDT09_04845	COG1785	Belongs to the alkaline phosphatase family
DDT09_04850	COG1388	LysM domain
DDT09_04850	COG0791	NLP P60 protein
DDT09_04855	COG0583	DNA-binding transcription factor activity
DDT09_04860	COG0372	Belongs to the citrate synthase family
DDT09_04865	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_04870	COG0531	amino acid
DDT09_04875	COG0733	neurotransmitter:sodium symporter activity
DDT09_04890	COG1595	DNA-templated transcription, initiation
DDT09_04895	COG0204	Acyl-transferase
DDT09_04900	COG1253	flavin adenine dinucleotide binding
DDT09_04905	COG0789	Transcriptional regulator
DDT09_04910	COG0436	Aminotransferase
DDT09_04915	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DDT09_04920	COG1253	flavin adenine dinucleotide binding
DDT09_04925	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DDT09_04930	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DDT09_04935	COG0584	glycerophosphoryl diester phosphodiesterase
DDT09_04945	COG0668	transmembrane transport
DDT09_04950	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DDT09_04955	COG0726	polysaccharide deacetylase
DDT09_04960	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DDT09_04965	COG3226	Transcriptional regulator
DDT09_04975	COG0589	response to stress
DDT09_04980	COG1132	(ABC) transporter
DDT09_04985	COG1132	(ABC) transporter
DDT09_04990	COG0702	epimerase
DDT09_05010	COG0189	ligase activity
DDT09_05015	COG0189	ligase activity
DDT09_05030	COG4335	DNA alkylation repair
DDT09_05035	COG0561	phosphatase activity
DDT09_05040	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DDT09_05050	COG0475	glutathione-regulated potassium exporter activity
DDT09_05055	COG0490	domain, Protein
DDT09_05065	COG1024	Enoyl-CoA hydratase
DDT09_05075	COG4152	abc transporter atp-binding protein
DDT09_05080	COG1668	transmembrane transport
DDT09_05085	COG0420	3'-5' exonuclease activity
DDT09_05090	COG4717	serine-type aminopeptidase activity
DDT09_05105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DDT09_05145	COG4980	gas vesicle protein
DDT09_05160	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DDT09_05165	COG0537	adenosine 5'-monophosphoramidase activity
DDT09_05170	COG1131	(ABC) transporter
DDT09_05175	COG4473	ABC transporter
DDT09_05185	COG1473	amidohydrolase
DDT09_05190	COG3069	C4-dicarboxylate transmembrane transporter activity
DDT09_05195	COG2329	Antibiotic biosynthesis monooxygenase
DDT09_05200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DDT09_05220	COG1309	transcriptional regulator
DDT09_05225	COG1511	domain protein
DDT09_05230	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DDT09_05240	COG1363	Peptidase, m42
DDT09_05245	COG1301	dicarboxylic acid transport
DDT09_05255	COG1234	tRNA 3'-trailer cleavage
DDT09_05260	COG0095	Lipoate-protein ligase
DDT09_05265	COG0702	epimerase
DDT09_05270	COG0318	PFAM AMP-dependent synthetase and ligase
DDT09_05280	COG0501	Belongs to the peptidase M48B family
DDT09_05285	COG1404	Belongs to the peptidase S8 family
DDT09_05295	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DDT09_05300	COG0406	alpha-ribazole phosphatase activity
DDT09_05305	COG0183	Belongs to the thiolase family
DDT09_05310	COG0318	PFAM AMP-dependent synthetase and ligase
DDT09_05315	COG1268	BioY protein
DDT09_05320	COG0840	transmembrane signaling receptor activity
DDT09_05325	COG0723	plastoquinol--plastocyanin reductase activity
DDT09_05325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DDT09_05330	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_05340	COG4903	ComK protein
DDT09_05350	COG5646	InterPro IPR014922
DDT09_05375	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DDT09_05390	COG0398	Pfam SNARE associated Golgi protein
DDT09_05395	COG0681	Belongs to the peptidase S26 family
DDT09_05400	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DDT09_05405	COG1846	Transcriptional regulator
DDT09_05410	COG3180	Ammonia monooxygenase
DDT09_05415	COG2814	Major facilitator Superfamily
DDT09_05425	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
DDT09_05445	COG0420	3'-5' exonuclease activity
DDT09_05450	COG0419	ATPase involved in DNA repair
DDT09_05455	COG1403	HNH endonuclease
DDT09_05495	COG0179	Fumarylacetoacetate (FAA) hydrolase
DDT09_05510	COG0367	asparagine synthase
DDT09_05515	COG1562	ergosterol biosynthetic process
DDT09_05520	COG0534	Mate efflux family protein
DDT09_05525	COG1917	Cupin 2, conserved barrel domain protein
DDT09_05525	COG2207	Transcriptional regulator
DDT09_05530	COG1609	Transcriptional regulator
DDT09_05535	COG0673	inositol 2-dehydrogenase activity
DDT09_05540	COG2318	DinB family
DDT09_05550	COG1357	PFAM Pentapeptide repeats (8 copies)
DDT09_05555	COG2153	protein acetylation
DDT09_05560	COG0646	methionine synthase
DDT09_05560	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DDT09_05570	COG2996	Protein conserved in bacteria
DDT09_05580	COG0840	transmembrane signaling receptor activity
DDT09_05585	COG2124	cytochrome p450
DDT09_05595	COG1307	EDD domain protein, DegV family
DDT09_05600	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DDT09_05615	COG0561	phosphatase activity
DDT09_05620	COG1073	alpha beta
DDT09_05625	COG2151	metal-sulfur cluster biosynthetic enzyme
DDT09_05635	COG0277	FAD linked oxidase domain protein
DDT09_05640	COG2271	Major facilitator Superfamily
DDT09_05660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DDT09_05665	COG0505	Belongs to the CarA family
DDT09_05670	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DDT09_05675	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DDT09_05695	COG2267	carboxylic ester hydrolase activity
DDT09_05705	COG1744	ABC transporter substrate-binding protein PnrA-like
DDT09_05720	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DDT09_05725	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DDT09_05730	COG5504	Zn-dependent protease
DDT09_05735	COG0444	Belongs to the ABC transporter superfamily
DDT09_05740	COG4608	Belongs to the ABC transporter superfamily
DDT09_05750	COG0601	transmembrane transport
DDT09_05755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DDT09_05765	COG0180	Tryptophanyl-tRNA synthetase
DDT09_05770	COG4166	transmembrane transport
DDT09_05775	COG0601	transmembrane transport
DDT09_05780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DDT09_05785	COG0444	Belongs to the ABC transporter superfamily
DDT09_05790	COG4608	Belongs to the ABC transporter superfamily
DDT09_05800	COG0456	acetyltransferase
DDT09_05805	COG1393	Belongs to the ArsC family
DDT09_05810	COG0861	Integral membrane protein TerC family
DDT09_05815	COG4862	establishment of competence for transformation
DDT09_05820	COG4469	Competence protein
DDT09_05825	COG1164	Oligoendopeptidase f
DDT09_05835	COG2346	COG2346, Truncated hemoglobins
DDT09_05840	COG0741	lytic transglycosylase activity
DDT09_05845	COG4116	CYTH
DDT09_05855	COG2357	RelA SpoT domain protein
DDT09_05860	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DDT09_05865	COG0564	pseudouridine synthase activity
DDT09_05880	COG0569	domain protein
DDT09_05880	COG0475	glutathione-regulated potassium exporter activity
DDT09_05885	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DDT09_05890	COG0352	thiamine-phosphate diphosphorylase activity
DDT09_05895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DDT09_05900	COG2104	thiamine diphosphate biosynthetic process
DDT09_05910	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DDT09_05915	COG0351	phosphomethylpyrimidine kinase
DDT09_05920	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DDT09_05975	COG0210	DNA helicase
DDT09_05995	COG1131	(ABC) transporter
DDT09_06005	COG2153	protein acetylation
DDT09_06015	COG2382	esterase
DDT09_06020	COG0626	cystathionine gamma-synthase activity
DDT09_06025	COG0626	cystathionine gamma-synthase activity
DDT09_06085	COG1484	DNA-dependent DNA replication
DDT09_06115	COG3655	Transcriptional regulator
DDT09_06155	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DDT09_06155	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DDT09_06205	COG1780	Probably involved in ribonucleotide reductase function
DDT09_06210	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DDT09_06225	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DDT09_06230	COG0756	dUTP diphosphatase activity
DDT09_06245	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
DDT09_06275	COG1595	DNA-templated transcription, initiation
DDT09_06305	COG5434	Belongs to the glycosyl hydrolase 28 family
DDT09_06305	COG3420	alginic acid biosynthetic process
DDT09_06310	COG4195	phage-related replication protein
DDT09_06320	COG1216	Glycosyl transferase, family 2
DDT09_06340	COG0582	viral genome integration into host DNA
DDT09_06425	COG1705	Flagellar rod assembly protein muramidase FlgJ
DDT09_06435	COG5434	Belongs to the glycosyl hydrolase 28 family
DDT09_06460	COG5632	N-Acetylmuramoyl-L-alanine amidase
DDT09_06460	COG3409	Peptidoglycan-binding domain 1 protein
DDT09_06460	COG1388	LysM domain
DDT09_06515	COG5444	nuclease activity
DDT09_06535	COG0135	phosphoribosylanthranilate isomerase activity
DDT09_06550	COG0346	lactoylglutathione lyase activity
DDT09_06555	COG2367	Beta-lactamase
DDT09_06560	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DDT09_06565	COG0477	Major facilitator Superfamily
DDT09_06570	COG1846	Transcriptional regulator
DDT09_06580	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DDT09_06585	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DDT09_06590	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DDT09_06595	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDT09_06595	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDT09_06600	COG1447	Phosphotransferase system cellobiose-specific component IIA
DDT09_06630	COG1285	pathogenesis
DDT09_06645	COG2205	protein histidine kinase activity
DDT09_06655	COG3383	formate dehydrogenase (NAD+) activity
DDT09_06660	COG2427	Protein of unknown function (DUF1641)
DDT09_06665	COG2124	cytochrome p450
DDT09_06670	COG1819	glycosyl
DDT09_06680	COG1587	Uroporphyrinogen-III synthase
DDT09_06685	COG0390	transport system, permease component
DDT09_06690	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DDT09_06695	COG0697	spore germination
DDT09_06700	COG4297	protein containing double-stranded beta helix domain
DDT09_06710	COG1252	NADH dehydrogenase
DDT09_06720	COG2211	Major facilitator Superfamily
DDT09_06725	COG1609	Transcriptional regulator
DDT09_06730	COG0246	Mannitol dehydrogenase
DDT09_06735	COG2721	sulfolactate sulfo-lyase activity
DDT09_06740	COG0730	response to heat
DDT09_06745	COG2318	DinB family
DDT09_06750	COG0457	Tetratricopeptide repeat
DDT09_06755	COG1388	LysM domain
DDT09_06755	COG5632	N-Acetylmuramoyl-L-alanine amidase
DDT09_06755	COG3409	Peptidoglycan-binding domain 1 protein
DDT09_06765	COG4195	phage-related replication protein
DDT09_06770	COG2856	Zn peptidase
DDT09_06775	COG1396	sequence-specific DNA binding
DDT09_06785	COG1522	sequence-specific DNA binding
DDT09_06790	COG1484	DNA-dependent DNA replication
DDT09_06805	COG1595	DNA-templated transcription, initiation
DDT09_06810	COG5484	DNA packaging
DDT09_06810	COG3728	DNA packaging
DDT09_06815	COG1783	phage Terminase large subunit
DDT09_06820	COG5518	Phage portal protein
DDT09_06825	COG0338	D12 class N6 adenine-specific DNA methyltransferase
DDT09_06830	COG4653	Phage capsid family
DDT09_06880	COG5412	phage tail tape measure protein
DDT09_06880	COG3953	SLT domain
DDT09_06880	COG5412	phage tail tape measure protein
DDT09_06880	COG5412	phage tail tape measure protein
DDT09_06880	COG3953	SLT domain
DDT09_06880	COG3953	SLT domain
DDT09_06885	COG1652	LysM domain
DDT09_06890	COG4193	domain, Protein
DDT09_06900	COG3628	GPW Gp25 family protein
DDT09_06905	COG3299	homolog of phage Mu protein gp47
DDT09_06910	COG3778	Protein conserved in bacteria
DDT09_06950	COG5632	N-Acetylmuramoyl-L-alanine amidase
DDT09_06950	COG3409	Peptidoglycan-binding domain 1 protein
DDT09_06965	COG0306	phosphate transporter
DDT09_06970	COG1392	Phosphate transport regulator
DDT09_06975	COG0531	amino acid
DDT09_06980	COG0346	lactoylglutathione lyase activity
DDT09_06985	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DDT09_06990	COG0463	Glycosyl transferase, family 2
DDT09_07000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DDT09_07005	COG0477	Major facilitator Superfamily
DDT09_07010	COG2362	D-Aminopeptidase
DDT09_07015	COG0601	transmembrane transport
DDT09_07020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DDT09_07025	COG0444	Belongs to the ABC transporter superfamily
DDT09_07030	COG4166	transmembrane transport
DDT09_07035	COG1619	proteins homologs of microcin C7 resistance protein MccF
DDT09_07040	COG4948	Mandelate Racemase Muconate Lactonizing
DDT09_07045	COG0791	NLP P60 protein
DDT09_07050	COG4608	Belongs to the ABC transporter superfamily
DDT09_07055	COG2706	6-phosphogluconolactonase activity
DDT09_07060	COG1834	amidinotransferase
DDT09_07065	COG1607	acyl-coa hydrolase
DDT09_07070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DDT09_07075	COG2076	Multidrug Resistance protein
DDT09_07080	COG2076	Multidrug Resistance protein
DDT09_07085	COG0788	formyltetrahydrofolate deformylase activity
DDT09_07090	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DDT09_07100	COG1764	response to oxidative stress
DDT09_07105	COG1846	Transcriptional regulator
DDT09_07110	COG1764	response to oxidative stress
DDT09_07125	COG0457	Tetratricopeptide repeat
DDT09_07125	COG0463	Glycosyl transferase, family 2
DDT09_07135	COG2814	Major facilitator Superfamily
DDT09_07140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DDT09_07150	COG1404	Belongs to the peptidase S8 family
DDT09_07155	COG1366	Belongs to the anti-sigma-factor antagonist family
DDT09_07160	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DDT09_07165	COG1122	ATPase activity
DDT09_07170	COG4721	ABC-type cobalt transport system, permease component
DDT09_07175	COG1388	LysM domain
DDT09_07175	COG3858	chitin binding
DDT09_07195	COG2239	Acts as a magnesium transporter
DDT09_07200	COG0789	Transcriptional regulator
DDT09_07215	COG1846	Transcriptional regulator
DDT09_07220	COG0726	polysaccharide deacetylase
DDT09_07225	COG3285	dna ligase
DDT09_07225	COG1793	dna ligase
DDT09_07230	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DDT09_07240	COG0586	Pfam SNARE associated Golgi protein
DDT09_07245	COG0861	Integral membrane protein TerC family
DDT09_07250	COG1191	sigma factor activity
DDT09_07275	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DDT09_07280	COG2323	membrane
DDT09_07290	COG3594	Acyltransferase
DDT09_07295	COG5002	protein histidine kinase activity
DDT09_07300	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DDT09_07315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DDT09_07320	COG0436	Aminotransferase
DDT09_07350	COG3852	Histidine kinase
DDT09_07355	COG1846	Transcriptional regulator
DDT09_07360	COG1360	Flagellar Motor Protein
DDT09_07365	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DDT09_07370	COG0542	response to heat
DDT09_07380	COG3949	Membrane
DDT09_07395	COG0720	synthase
DDT09_07400	COG0602	queuosine metabolic process
DDT09_07405	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DDT09_07410	COG1733	regulation of RNA biosynthetic process
DDT09_07415	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_07435	COG4873	Protein conserved in bacteria
DDT09_07445	COG3773	Cell wall hydrolase
DDT09_07450	COG2244	polysaccharide biosynthetic process
DDT09_07455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DDT09_07460	COG2217	Heavy metal translocating P-type atpase
DDT09_07465	COG0006	proline dipeptidase activity
DDT09_07470	COG1609	Transcriptional regulator
DDT09_07475	COG3711	transcriptional antiterminator
DDT09_07480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDT09_07480	COG1263	PTS System
DDT09_07480	COG2190	(PTS) system
DDT09_07485	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDT09_07490	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DDT09_07500	COG1533	DNA photolyase activity
DDT09_07505	COG0840	transmembrane signaling receptor activity
DDT09_07510	COG2084	Dehydrogenase
DDT09_07520	COG0347	Belongs to the P(II) protein family
DDT09_07525	COG2340	Cysteine-rich secretory protein family
DDT09_07530	COG0768	penicillin binding
DDT09_07540	COG0436	Aminotransferase
DDT09_07550	COG0835	chemotaxis
DDT09_07550	COG0784	Response regulator, receiver
DDT09_07560	COG2814	Major facilitator Superfamily
DDT09_07565	COG1376	ErfK ybiS ycfS ynhG family protein
DDT09_07570	COG1408	metallophosphoesterase
DDT09_07575	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_07585	COG2200	EAL domain
DDT09_07590	COG4703	Protein of unknown function (DUF1797)
DDT09_07595	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
DDT09_07605	COG0517	IMP dehydrogenase activity
DDT09_07610	COG0583	DNA-binding transcription factor activity
DDT09_07615	COG0716	FMN binding
DDT09_07625	COG0716	FMN binding
DDT09_07645	COG0668	transmembrane transport
DDT09_07650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DDT09_07670	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DDT09_07675	COG0303	'Molybdopterin
DDT09_07680	COG1763	Mo-molybdopterin cofactor biosynthetic process
DDT09_07685	COG0314	molybdopterin synthase activity
DDT09_07690	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DDT09_07700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DDT09_07705	COG1136	(ABC) transporter
DDT09_07710	COG0577	efflux transmembrane transporter activity
DDT09_07715	COG1349	DNA-binding transcription factor activity
DDT09_07720	COG1105	Belongs to the carbohydrate kinase PfkB family
DDT09_07725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDT09_07725	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDT09_07725	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDT09_07730	COG0681	Belongs to the peptidase S26 family
DDT09_07740	COG0488	(ABC) transporter
DDT09_07745	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DDT09_07750	COG2309	aminopeptidase activity
DDT09_07760	COG1077	Cell shape determining protein MreB Mrl
DDT09_07770	COG2002	toxin-antitoxin pair type II binding
DDT09_07775	COG3852	Histidine kinase
DDT09_07780	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
DDT09_07780	COG2105	PFAM AIG2 family protein
DDT09_07785	COG0569	domain protein
DDT09_07795	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DDT09_07805	COG0561	phosphatase activity
DDT09_07810	COG0242	peptide deformylase activity
DDT09_07820	COG0497	DNA recombination
DDT09_07835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDT09_07835	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_07835	COG3321	synthase
DDT09_07835	COG4221	oxidoreductase activity
DDT09_07840	COG3321	synthase
DDT09_07840	COG0300	oxidoreductase activity
DDT09_07840	COG4221	oxidoreductase activity
DDT09_07840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDT09_07845	COG3321	synthase
DDT09_07845	COG4221	oxidoreductase activity
DDT09_07845	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_07845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDT09_07850	COG0300	oxidoreductase activity
DDT09_07850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDT09_07850	COG3321	synthase
DDT09_07850	COG4221	oxidoreductase activity
DDT09_07855	COG4221	oxidoreductase activity
DDT09_07855	COG3321	synthase
DDT09_07855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDT09_07855	COG0300	oxidoreductase activity
DDT09_07860	COG3321	synthase
DDT09_07860	COG0300	oxidoreductase activity
DDT09_07860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDT09_07860	COG4221	oxidoreductase activity
DDT09_07865	COG4221	oxidoreductase activity
DDT09_07865	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_07865	COG3321	synthase
DDT09_07865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDT09_07870	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DDT09_07875	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DDT09_07880	COG0022	dehydrogenase e1 component
DDT09_07885	COG0508	dehydrogenase complex catalyzes the overall conversion of
DDT09_07890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DDT09_07895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DDT09_07910	COG1982	Orn Lys Arg decarboxylase major
DDT09_07935	COG0483	inositol monophosphate 1-phosphatase activity
DDT09_07945	COG3227	Zinc metalloprotease (Elastase)
DDT09_07960	COG1595	DNA-templated transcription, initiation
DDT09_07990	COG4896	Protein conserved in bacteria
DDT09_08000	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DDT09_08005	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DDT09_08010	COG2066	Belongs to the glutaminase family
DDT09_08020	COG0772	Belongs to the SEDS family
DDT09_08025	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DDT09_08040	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DDT09_08040	COG2010	Cytochrome c
DDT09_08045	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DDT09_08050	COG1845	cytochrome c oxidase, subunit III
DDT09_08055	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DDT09_08060	COG3336	cytochrome c oxidase
DDT09_08070	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
DDT09_08075	COG2340	Cysteine-rich secretory protein family
DDT09_08090	COG3679	Belongs to the UPF0342 family
DDT09_08105	COG0742	ribosomal rna small subunit methyltransferase
DDT09_08115	COG3314	Sporulation integral membrane protein YlbJ
DDT09_08120	COG1752	Esterase of the alpha-beta hydrolase superfamily
DDT09_08125	COG3480	Lon protease (S16) C-terminal proteolytic domain
DDT09_08140	COG1399	metal-binding, possibly nucleic acid-binding protein
DDT09_08145	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DDT09_08160	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DDT09_08180	COG4839	cell division protein FtsL
DDT09_08190	COG0768	penicillin binding
DDT09_08210	COG0772	Belongs to the SEDS family
DDT09_08225	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DDT09_08230	COG0849	cell division
DDT09_08235	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DDT09_08240	COG1404	Belongs to the peptidase S8 family
DDT09_08240	COG4412	M6 family metalloprotease domain protein
DDT09_08250	COG1191	sigma factor activity
DDT09_08255	COG1191	sigma factor activity
DDT09_08260	COG1119	ATPase activity
DDT09_08265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DDT09_08270	COG1873	PFAM PRC-barrel domain
DDT09_08280	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DDT09_08290	COG0762	integral membrane protein
DDT09_08295	COG2302	S4 RNA-binding domain
DDT09_08300	COG3599	regulation of cell shape
DDT09_08310	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DDT09_08315	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DDT09_08325	COG0564	pseudouridine synthase activity
DDT09_08335	COG2233	PERMEase
DDT09_08345	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DDT09_08350	COG0505	Belongs to the CarA family
DDT09_08355	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DDT09_08370	COG0284	orotidine-5'-phosphate decarboxylase activity
DDT09_08375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DDT09_08385	COG0306	phosphate transporter
DDT09_08400	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DDT09_08405	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
DDT09_08410	COG1648	precorrin-2 dehydrogenase activity
DDT09_08425	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DDT09_08430	COG1561	YicC-like family, N-terminal region
DDT09_08435	COG2052	Domain of unknown function (DUF370)
DDT09_08440	COG0194	GDP metabolic process
DDT09_08450	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DDT09_08455	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DDT09_08460	COG0242	peptide deformylase activity
DDT09_08470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DDT09_08470	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DDT09_08480	COG0631	protein serine/threonine phosphatase activity
DDT09_08485	COG0515	serine threonine protein kinase
DDT09_08485	COG2815	serine threonine protein kinase
DDT09_08495	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DDT09_08500	COG1564	THIamine pyrophosphokinase
DDT09_08515	COG1302	Protein conserved in bacteria
DDT09_08520	COG1461	Dihydroxyacetone kinase
DDT09_08525	COG1760	l-serine dehydratase
DDT09_08530	COG1760	l-serine dehydratase
DDT09_08535	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DDT09_08550	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DDT09_08555	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_08560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDT09_08570	COG1196	nuclear chromosome segregation
DDT09_08575	COG0552	protein localization to endoplasmic reticulum
DDT09_08590	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DDT09_08600	COG1837	Belongs to the UPF0109 family
DDT09_08625	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DDT09_08640	COG2257	FlhB HrpN YscU SpaS Family
DDT09_08650	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DDT09_08655	COG0758	DNA mediated transformation
DDT09_08660	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DDT09_08670	COG4974	Belongs to the 'phage' integrase family
DDT09_08690	COG1815	bacterial-type flagellum-dependent cell motility
DDT09_08695	COG1558	bacterial-type flagellum-dependent cell motility
DDT09_08700	COG1677	Flagellar hook-basal body complex protein FliE
DDT09_08705	COG1766	The M ring may be actively involved in energy transduction
DDT09_08710	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DDT09_08715	COG1317	bacterial-type flagellum organization
DDT09_08720	COG1157	protein secretion by the type III secretion system
DDT09_08725	COG2882	bacterial-type flagellum organization
DDT09_08730	COG3334	PFAM MgtE intracellular
DDT09_08735	COG3144	bacterial-type flagellum assembly
DDT09_08740	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DDT09_08745	COG4786	Flagellar basal body rod
DDT09_08750	COG1582	Flagellar protein (FlbD)
DDT09_08755	COG1580	Controls the rotational direction of flagella during chemotaxis
DDT09_08760	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DDT09_08765	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DDT09_08765	COG1776	CheC inhibitor of MCP methylation
DDT09_08770	COG2201	protein-glutamate methylesterase activity
DDT09_08775	COG3190	flagellar
DDT09_08780	COG1338	Plays a role in the flagellum-specific transport system
DDT09_08785	COG1987	bacterial-type flagellum assembly
DDT09_08790	COG1684	flagellar biosynthetic protein fliR
DDT09_08795	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DDT09_08800	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DDT09_08805	COG1419	protein localization to endoplasmic reticulum
DDT09_08810	COG0455	bacterial-type flagellum organization
DDT09_08815	COG2201	protein-glutamate methylesterase activity
DDT09_08820	COG0643	Histidine kinase
DDT09_08820	COG2198	Histidine kinase
DDT09_08825	COG0835	chemotaxis
DDT09_08830	COG1776	CheC inhibitor of MCP methylation
DDT09_08840	COG1191	sigma factor activity
DDT09_08870	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DDT09_08875	COG4589	Belongs to the CDS family
DDT09_08885	COG0750	zinc metalloprotease
DDT09_08895	COG2176	DNA-directed DNA polymerase activity
DDT09_08905	COG0195	Participates in both transcription termination and antitermination
DDT09_08910	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DDT09_08915	COG1358	cellular component organization or biogenesis
DDT09_08925	COG1550	Protein conserved in bacteria
DDT09_08940	COG0196	riboflavin kinase activity
DDT09_08955	COG0726	polysaccharide deacetylase
DDT09_08960	COG0612	Peptidase, M16
DDT09_08965	COG1873	PFAM PRC-barrel domain
DDT09_08970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DDT09_08975	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DDT09_08980	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DDT09_08985	COG0527	aspartate kinase activity
DDT09_08995	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DDT09_09000	COG0740	serine-type endopeptidase activity
DDT09_09010	COG4980	gas vesicle protein
DDT09_09010	COG1674	ftsk spoiiie
DDT09_09015	COG2188	Transcriptional regulator
DDT09_09020	COG2814	Major facilitator Superfamily
DDT09_09025	COG1846	Transcriptional regulator
DDT09_09030	COG1033	growth of symbiont in host cell
DDT09_09030	COG2409	Drug exporters of the RND superfamily
DDT09_09035	COG0612	Peptidase, M16
DDT09_09040	COG0612	Peptidase, M16
DDT09_09045	COG0300	oxidoreductase activity
DDT09_09060	COG1426	Protein conserved in bacteria
DDT09_09065	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DDT09_09080	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DDT09_09090	COG1692	metallophosphoesterase
DDT09_09095	COG2359	stage V sporulation protein S
DDT09_09115	COG4550	Control of competence regulator ComK, YlbF/YmcA
DDT09_09205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDT09_09210	COG3425	synthase
DDT09_09215	COG1024	Enoyl-CoA hydratase
DDT09_09220	COG1024	Enoyl-CoA hydratase
DDT09_09225	COG0318	PFAM AMP-dependent synthetase and ligase
DDT09_09225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDT09_09225	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_09225	COG3321	synthase
DDT09_09225	COG0300	oxidoreductase activity
DDT09_09230	COG3321	synthase
DDT09_09230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDT09_09230	COG0300	oxidoreductase activity
DDT09_09230	COG4221	oxidoreductase activity
DDT09_09235	COG3321	synthase
DDT09_09235	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_09235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDT09_09235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDT09_09235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDT09_09235	COG3321	synthase
DDT09_09235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DDT09_09235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDT09_09235	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_09235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DDT09_09240	COG4221	oxidoreductase activity
DDT09_09240	COG3321	synthase
DDT09_09240	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_09240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDT09_09245	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DDT09_09245	COG3321	synthase
DDT09_09245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDT09_09245	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DDT09_09250	COG2124	cytochrome p450
DDT09_09255	COG3209	COG3209 Rhs family protein
DDT09_09260	COG3619	membrane
DDT09_09270	COG1404	Belongs to the peptidase S8 family
DDT09_09280	COG4195	phage-related replication protein
DDT09_09285	COG1764	response to oxidative stress
DDT09_09295	COG2076	Multidrug Resistance protein
DDT09_09335	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DDT09_09340	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DDT09_09345	COG4112	unkown
DDT09_09350	COG0860	N-Acetylmuramoyl-L-alanine amidase
DDT09_09360	COG0464	growth
DDT09_09365	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DDT09_09370	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
DDT09_09375	COG0789	Transcriptional regulator
DDT09_09380	COG0174	glutamine synthetase
DDT09_09415	COG2211	Major facilitator Superfamily
DDT09_09420	COG3507	Belongs to the glycosyl hydrolase 43 family
DDT09_09435	COG1070	Carbohydrate kinase
DDT09_09440	COG3848	Pyruvate phosphate dikinase
DDT09_09440	COG0574	Belongs to the PEP-utilizing enzyme family
DDT09_09465	COG2378	regulation of single-species biofilm formation
DDT09_09470	COG2318	DinB family
DDT09_09475	COG1064	alcohol dehydrogenase
DDT09_09510	COG5444	nuclease activity
DDT09_09565	COG3397	chitin binding
DDT09_09580	COG5434	Belongs to the glycosyl hydrolase 28 family
DDT09_09590	COG0756	dUTP diphosphatase activity
DDT09_09600	COG4195	phage-related replication protein
DDT09_09630	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DDT09_09640	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DDT09_09660	COG0785	Cytochrome C biogenesis protein
DDT09_09665	COG2201	protein-glutamate methylesterase activity
DDT09_09670	COG4846	Membrane protein involved in cytochrome C biogenesis
DDT09_09680	COG0071	Belongs to the small heat shock protein (HSP20) family
DDT09_09695	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DDT09_09700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DDT09_09720	COG0824	Thioesterase
DDT09_09730	COG4841	protein insertion into membrane
DDT09_09740	COG1832	CoA-binding protein
DDT09_09745	COG0187	DNA topoisomerase II activity
DDT09_09750	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DDT09_09760	COG1115	amino acid carrier protein
DDT09_09770	COG1063	alcohol dehydrogenase
DDT09_09775	COG0800	Aldolase
DDT09_09780	COG1312	Catalyzes the dehydration of D-mannonate
DDT09_09785	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_09790	COG1609	Transcriptional regulator
DDT09_09795	COG2271	Major facilitator Superfamily
DDT09_09820	COG0577	efflux transmembrane transporter activity
DDT09_09820	COG1136	(ABC) transporter
DDT09_09845	COG2205	protein histidine kinase activity
DDT09_09850	COG0745	RESPONSE REGULATOR receiver
DDT09_09860	COG3507	Belongs to the glycosyl hydrolase 43 family
DDT09_09890	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_09895	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DDT09_09900	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DDT09_09905	COG2610	gluconate transmembrane transporter activity
DDT09_09910	COG2124	cytochrome p450
DDT09_09915	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DDT09_09930	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DDT09_09940	COG2246	polysaccharide biosynthetic process
DDT09_09945	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DDT09_09950	COG0586	Pfam SNARE associated Golgi protein
DDT09_09955	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DDT09_09960	COG1024	Enoyl-CoA hydratase
DDT09_09965	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DDT09_09970	COG0511	ligase activity, forming carbon-carbon bonds
DDT09_09975	COG0439	Biotin carboxylase
DDT09_09980	COG0318	PFAM AMP-dependent synthetase and ligase
DDT09_09985	COG1960	acyl-CoA dehydrogenase activity
DDT09_09990	COG1649	PFAM Uncharacterised BCR, COG1649
DDT09_10000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDT09_10000	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DDT09_10005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDT09_10010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDT09_10015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDT09_10020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDT09_10030	COG2027	D-alanyl-D-alanine carboxypeptidase
DDT09_10035	COG2017	converts alpha-aldose to the beta-anomer
DDT09_10040	COG0534	Mate efflux family protein
DDT09_10055	COG0582	viral genome integration into host DNA
DDT09_10060	COG0166	Belongs to the GPI family
DDT09_10065	COG0405	Gamma-glutamyltransferase
DDT09_10070	COG2814	Major facilitator Superfamily
DDT09_10075	COG0640	Transcriptional regulator
DDT09_10080	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DDT09_10090	COG0604	alcohol dehydrogenase
DDT09_10100	COG0493	'glutamate synthase
DDT09_10105	COG0070	glutamate synthase
DDT09_10105	COG0067	glutamate synthase
DDT09_10105	COG0069	glutamate synthase activity
DDT09_10110	COG0583	DNA-binding transcription factor activity
DDT09_10115	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DDT09_10130	COG0300	oxidoreductase activity
DDT09_10135	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DDT09_10145	COG2814	Major facilitator Superfamily
DDT09_10150	COG1070	Carbohydrate kinase
DDT09_10155	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DDT09_10160	COG0243	molybdopterin cofactor binding
DDT09_10190	COG5444	nuclease activity
DDT09_10195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DDT09_10200	COG0662	Cupin 2, conserved barrel domain protein
DDT09_10200	COG2207	Transcriptional regulator
DDT09_10205	COG1309	transcriptional regulator
DDT09_10210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DDT09_10220	COG0640	Transcriptional regulator
DDT09_10225	COG0741	lytic transglycosylase activity
DDT09_10230	COG2322	membrane
DDT09_10245	COG1619	proteins homologs of microcin C7 resistance protein MccF
DDT09_10255	COG3584	3D domain protein
DDT09_10255	COG1388	LysM domain
DDT09_10260	COG0514	ATP-dependent DNA helicase (RecQ)
DDT09_10270	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DDT09_10275	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DDT09_10290	COG0071	Belongs to the small heat shock protein (HSP20) family
DDT09_10320	COG1012	belongs to the aldehyde dehydrogenase family
DDT09_10325	COG1657	PFAM Prenyltransferase squalene oxidase
DDT09_10330	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DDT09_10335	COG0733	neurotransmitter:sodium symporter activity
DDT09_10340	COG0385	Bile acid
DDT09_10345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DDT09_10350	COG0508	dehydrogenase complex catalyzes the overall conversion of
DDT09_10360	COG4548	von Willebrand factor, type A
DDT09_10365	COG0714	Associated with various cellular activities
DDT09_10370	COG2032	superoxide dismutase activity
DDT09_10375	COG1388	LysM domain
DDT09_10375	COG0791	NLP P60 protein
DDT09_10380	COG1819	glycosyl
DDT09_10385	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DDT09_10390	COG0534	Mate efflux family protein
DDT09_10395	COG1366	Belongs to the anti-sigma-factor antagonist family
DDT09_10400	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DDT09_10405	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DDT09_10415	COG2962	Rard protein
DDT09_10430	COG1942	4-Oxalocrotonate Tautomerase
DDT09_10440	COG1733	regulation of RNA biosynthetic process
DDT09_10445	COG0778	Nitroreductase
DDT09_10450	COG0400	carboxylic ester hydrolase activity
DDT09_10455	COG0346	lactoylglutathione lyase activity
DDT09_10465	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DDT09_10475	COG2723	6-phospho-beta-galactosidase activity
DDT09_10480	COG2188	Transcriptional regulator
DDT09_10485	COG3409	Peptidoglycan-binding domain 1 protein
DDT09_10485	COG0793	Belongs to the peptidase S41A family
DDT09_10490	COG2226	methyltransferase
DDT09_10500	COG1876	peptidase activity
DDT09_10520	COG0671	phosphoesterase, PA-phosphatase related
DDT09_10550	COG1509	lysine 2,3-aminomutase activity
DDT09_10555	COG0456	acetyltransferase
DDT09_10560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DDT09_10565	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DDT09_10570	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DDT09_10575	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DDT09_10580	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
DDT09_10590	COG0456	acetyltransferase
DDT09_10595	COG0463	Glycosyl transferase, family 2
DDT09_10610	COG4641	Protein conserved in bacteria
DDT09_10620	COG1086	Polysaccharide biosynthesis protein
DDT09_10635	COG1846	Transcriptional regulator
DDT09_10640	COG4698	Protein conserved in bacteria
DDT09_10645	COG2755	lipolytic protein G-D-S-L family
DDT09_10650	COG1999	signal sequence binding
DDT09_10660	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DDT09_10665	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DDT09_10670	COG1272	protein, Hemolysin III
DDT09_10675	COG0204	Acyl-transferase
DDT09_10680	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DDT09_10695	COG2521	methyltransferase
DDT09_10695	COG2136	Putative SAM-dependent methyltransferase
DDT09_10710	COG1413	lyase activity
DDT09_10715	COG1418	mRNA catabolic process
DDT09_10720	COG0386	Belongs to the glutathione peroxidase family
DDT09_10730	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DDT09_10735	COG1278	Cold shock
DDT09_10755	COG0328	RNA-DNA hybrid ribonuclease activity
DDT09_10760	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DDT09_10765	COG0328	RNA-DNA hybrid ribonuclease activity
DDT09_10775	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DDT09_10790	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DDT09_10800	COG1755	Isoprenylcysteine carboxyl methyltransferase
DDT09_10805	COG3424	synthase
DDT09_10835	COG1335	isochorismatase
DDT09_10845	COG2233	PERMEase
DDT09_10855	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DDT09_10860	COG1199	ATP-dependent helicase activity
DDT09_10875	COG0116	Belongs to the methyltransferase superfamily
DDT09_10900	COG3359	exonuclease
DDT09_10905	COG1111	helicase
DDT09_10905	COG1205	dead DEAH box helicase
DDT09_10910	COG2190	(PTS) system
DDT09_10915	COG0071	Belongs to the small heat shock protein (HSP20) family
DDT09_10955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DDT09_10955	COG4499	WXG100 protein secretion system (Wss), protein YukC
DDT09_10965	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DDT09_10970	COG3935	DnaD domain protein
DDT09_10980	COG0436	Aminotransferase
DDT09_10985	COG5353	protein conserved in bacteria
DDT09_10995	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DDT09_10995	COG1199	ATP-dependent helicase activity
DDT09_11025	COG0438	transferase activity, transferring glycosyl groups
DDT09_11030	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DDT09_11045	COG1694	Mazg nucleotide pyrophosphohydrolase
DDT09_11050	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DDT09_11055	COG2140	Oxalate decarboxylase
DDT09_11065	COG4347	Protein of unknown function (DUF1405)
DDT09_11070	COG2010	Cytochrome c
DDT09_11070	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DDT09_11075	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DDT09_11080	COG0723	plastoquinol--plastocyanin reductase activity
DDT09_11095	COG0457	Tetratricopeptide repeat
DDT09_11105	COG0287	Prephenate dehydrogenase
DDT09_11140	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DDT09_11145	COG4401	Chorismate mutase type I
DDT09_11160	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DDT09_11165	COG0105	UTP biosynthetic process
DDT09_11170	COG0142	geranyltranstransferase activity
DDT09_11180	COG0142	geranyltranstransferase activity
DDT09_11195	COG0776	regulation of translation
DDT09_11200	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DDT09_11240	COG0539	negative regulation of cytoplasmic translation
DDT09_11250	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
DDT09_11255	COG2959	enzyme of heme biosynthesis
DDT09_11260	COG3773	Cell wall hydrolase
DDT09_11260	COG3409	Peptidoglycan-binding domain 1 protein
DDT09_11265	COG2339	peptidase activity
DDT09_11270	COG0492	ferredoxin-NADP+ reductase activity
DDT09_11275	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DDT09_11280	COG4862	establishment of competence for transformation
DDT09_11285	COG1408	metallophosphoesterase
DDT09_11295	COG1388	LysM domain
DDT09_11300	COG1266	CAAX protease self-immunity
DDT09_11305	COG0514	ATP-dependent DNA helicase (RecQ)
DDT09_11310	COG4955	Helix-turn-helix domain
DDT09_11315	COG1141	Ferredoxin
DDT09_11320	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DDT09_11325	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DDT09_11335	COG1595	DNA-templated transcription, initiation
DDT09_11340	COG5002	protein histidine kinase activity
DDT09_11345	COG0745	RESPONSE REGULATOR receiver
DDT09_11350	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DDT09_11355	COG1333	cytochrome c biogenesis protein
DDT09_11360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DDT09_11365	COG1187	pseudouridine synthase activity
DDT09_11370	COG0700	Nucleoside recognition
DDT09_11375	COG2715	membrane protein required for spore maturation
DDT09_11380	COG1686	Belongs to the peptidase S11 family
DDT09_11405	COG1547	Domain of unknown function (DUF309)
DDT09_11415	COG0456	acetyltransferase
DDT09_11430	COG0307	riboflavin synthase, alpha
DDT09_11435	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DDT09_11435	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DDT09_11445	COG0681	Belongs to the peptidase S26 family
DDT09_11455	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DDT09_11460	COG4086	secreted protein
DDT09_11465	COG0019	diaminopimelate decarboxylase activity
DDT09_11470	COG0697	spore germination
DDT09_11485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DDT09_11505	COG1191	sigma factor activity
DDT09_11515	COG1366	Belongs to the anti-sigma-factor antagonist family
DDT09_11520	COG1686	Belongs to the peptidase S11 family
DDT09_11525	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DDT09_11530	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DDT09_11535	COG4974	Belongs to the 'phage' integrase family
DDT09_11545	COG0735	belongs to the Fur family
DDT09_11550	COG1300	Membrane
DDT09_11565	COG0281	malic enzyme
DDT09_11570	COG1757	Na H antiporter
DDT09_11575	COG1027	Aspartate ammonia-lyase
DDT09_11580	COG0252	asparaginase activity
DDT09_11585	COG1396	sequence-specific DNA binding
DDT09_11590	COG1379	DNA repair
DDT09_11595	COG0494	nUDIX hydrolase
DDT09_11605	COG0667	Aldo Keto reductase
DDT09_11615	COG1073	alpha beta
DDT09_11625	COG4918	Iron-sulphur cluster biosynthesis
DDT09_11630	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DDT09_11630	COG0456	acetyltransferase
DDT09_11635	COG2329	Antibiotic biosynthesis monooxygenase
DDT09_11640	COG0456	acetyltransferase
DDT09_11645	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DDT09_11660	COG0628	permease
DDT09_11670	COG0346	lactoylglutathione lyase activity
DDT09_11680	COG3048	D-serine ammonia-lyase activity
DDT09_11685	COG0300	oxidoreductase activity
DDT09_11690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DDT09_11695	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DDT09_11700	COG1024	Enoyl-CoA hydratase
DDT09_11705	COG3425	synthase
DDT09_11710	COG2124	cytochrome p450
DDT09_11715	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_11715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DDT09_11715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDT09_11715	COG3321	synthase
DDT09_11715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDT09_11720	COG3321	synthase
DDT09_11720	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_11720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDT09_11720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DDT09_11720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDT09_11725	COG0318	PFAM AMP-dependent synthetase and ligase
DDT09_11725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDT09_11725	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_11725	COG0300	oxidoreductase activity
DDT09_11725	COG3321	synthase
DDT09_11730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDT09_11730	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_11730	COG0300	oxidoreductase activity
DDT09_11730	COG3321	synthase
DDT09_11730	COG0318	PFAM AMP-dependent synthetase and ligase
DDT09_11735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DDT09_11735	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_11735	COG3321	synthase
DDT09_11735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDT09_11735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDT09_11740	COG3321	synthase
DDT09_11740	COG0300	oxidoreductase activity
DDT09_11740	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_11740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDT09_11740	COG0318	PFAM AMP-dependent synthetase and ligase
DDT09_11745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDT09_11745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DDT09_11745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDT09_11745	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_11745	COG3321	synthase
DDT09_11750	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_11755	COG0318	PFAM AMP-dependent synthetase and ligase
DDT09_11770	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DDT09_11770	COG2070	2-Nitropropane dioxygenase
DDT09_11780	COG0250	Participates in transcription elongation, termination and antitermination
DDT09_11805	COG0596	Alpha beta hydrolase
DDT09_11820	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DDT09_11825	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DDT09_11840	COG0706	membrane insertase activity
DDT09_11845	COG2195	Cleaves the N-terminal amino acid of tripeptides
DDT09_11850	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DDT09_11855	COG0346	lactoylglutathione lyase activity
DDT09_11860	COG1376	ErfK ybiS ycfS ynhG family protein
DDT09_11865	COG4129	membrane
DDT09_11870	COG1126	abc transporter atp-binding protein
DDT09_11875	COG0765	amino acid transport
DDT09_11880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDT09_11890	COG1597	lipid kinase activity
DDT09_11895	COG0508	dehydrogenase complex catalyzes the overall conversion of
DDT09_11900	COG0022	dehydrogenase e1 component
DDT09_11905	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DDT09_11910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DDT09_11915	COG3426	butyrate kinase activity
DDT09_11920	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DDT09_11925	COG0280	phosphate acetyltransferase
DDT09_11930	COG3290	protein histidine kinase activity
DDT09_11930	COG3829	transcription factor binding
DDT09_11940	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DDT09_11945	COG2079	MmgE PrpD family protein
DDT09_11950	COG0372	Belongs to the citrate synthase family
DDT09_11955	COG1960	acyl-CoA dehydrogenase activity
DDT09_11960	COG1250	3-hydroxyacyl-CoA dehydrogenase
DDT09_11965	COG0183	Belongs to the thiolase family
DDT09_11970	COG0584	glycerophosphoryl diester phosphodiesterase
DDT09_11975	COG0860	N-Acetylmuramoyl-L-alanine amidase
DDT09_11995	COG1902	pentaerythritol trinitrate reductase activity
DDT09_12010	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DDT09_12015	COG0745	RESPONSE REGULATOR receiver
DDT09_12020	COG0750	zinc metalloprotease
DDT09_12025	COG0497	DNA recombination
DDT09_12035	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DDT09_12045	COG0142	geranyltranstransferase activity
DDT09_12055	COG1570	exodeoxyribonuclease VII activity
DDT09_12070	COG1302	Protein conserved in bacteria
DDT09_12075	COG0439	Biotin carboxylase
DDT09_12080	COG0511	ligase activity, forming carbon-carbon bonds
DDT09_12120	COG3854	ATPases associated with a variety of cellular activities
DDT09_12135	COG0006	proline dipeptidase activity
DDT09_12145	COG3872	metal-dependent enzyme
DDT09_12155	COG1752	Esterase of the alpha-beta hydrolase superfamily
DDT09_12170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DDT09_12190	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DDT09_12205	COG1396	sequence-specific DNA binding
DDT09_12215	COG0681	Belongs to the peptidase S26 family
DDT09_12240	COG4940	Competence protein ComGF
DDT09_12250	COG4970	Tfp pilus assembly protein FimT
DDT09_12255	COG4537	Required for transformation and DNA binding
DDT09_12260	COG1459	type II secretion system
DDT09_12265	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DDT09_12270	COG0598	Magnesium transport protein CorA
DDT09_12275	COG1253	flavin adenine dinucleotide binding
DDT09_12280	COG1366	Belongs to the anti-sigma-factor antagonist family
DDT09_12290	COG1393	Belongs to the ArsC family
DDT09_12300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DDT09_12310	COG0011	TIGRFAM Protein of
DDT09_12320	COG2866	Carboxypeptidase
DDT09_12325	COG1940	carbohydrate kinase activity
DDT09_12330	COG4483	Protein conserved in bacteria
DDT09_12335	COG1757	Na H antiporter
DDT09_12345	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DDT09_12350	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DDT09_12360	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DDT09_12365	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DDT09_12370	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DDT09_12375	COG0581	inorganic phosphate transmembrane transporter activity
DDT09_12380	COG0573	inorganic phosphate transmembrane transporter activity
DDT09_12385	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DDT09_12395	COG0477	Major facilitator Superfamily
DDT09_12400	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DDT09_12405	COG2839	Protein conserved in bacteria
DDT09_12410	COG5521	maltodextrose utilization protein MalA
DDT09_12415	COG1388	LysM domain
DDT09_12425	COG4709	membrane
DDT09_12430	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
DDT09_12435	COG0735	belongs to the Fur family
DDT09_12440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DDT09_12455	COG0513	Belongs to the DEAD box helicase family
DDT09_12470	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DDT09_12475	COG2384	SAM-dependent methyltransferase
DDT09_12480	COG2010	Cytochrome c
DDT09_12485	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DDT09_12490	COG0358	DNA primase activity
DDT09_12505	COG0517	IMP dehydrogenase activity
DDT09_12510	COG0751	glycine-tRNA ligase activity
DDT09_12530	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DDT09_12535	COG0295	cytidine deaminase activity
DDT09_12540	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DDT09_12550	COG1480	7TM receptor with intracellular HD hydrolase
DDT09_12555	COG1702	phosphate starvation-inducible protein PhoH
DDT09_12560	COG0561	phosphatase activity
DDT09_12575	COG4864	UPF0365 protein
DDT09_12580	COG1030	water channel activity
DDT09_12585	COG1610	YqeY-like protein
DDT09_12590	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DDT09_12595	COG1283	sodium-dependent phosphate transmembrane transporter activity
DDT09_12600	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DDT09_12605	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DDT09_12635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DDT09_12650	COG0860	N-Acetylmuramoyl-L-alanine amidase
DDT09_12665	COG1466	dna polymerase III delta subunit
DDT09_12675	COG2333	competence protein COMEC
DDT09_12675	COG0658	competence protein
DDT09_12680	COG2131	deaminase
DDT09_12685	COG1596	polysaccharide export
DDT09_12685	COG1555	photosystem II stabilization
DDT09_12690	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DDT09_12695	COG2226	methyltransferase
DDT09_12700	COG0799	negative regulation of ribosome biogenesis
DDT09_12705	COG1713	HD superfamily hydrolase involved in NAD metabolism
DDT09_12715	COG1534	Rna-binding protein
DDT09_12720	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DDT09_12725	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DDT09_12730	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DDT09_12740	COG2755	lipolytic protein G-D-S-L family
DDT09_12745	COG0726	polysaccharide deacetylase
DDT09_12750	COG0398	Pfam SNARE associated Golgi protein
DDT09_12785	COG2207	Transcriptional regulator
DDT09_12785	COG3708	Transcriptional regulator
DDT09_12790	COG0583	DNA-binding transcription factor activity
DDT09_12805	COG2814	Major facilitator Superfamily
DDT09_12815	COG0456	acetyltransferase
DDT09_12820	COG2318	DinB family
DDT09_12830	COG0561	phosphatase activity
DDT09_12845	COG1482	cell wall glycoprotein biosynthetic process
DDT09_12850	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDT09_12850	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDT09_12850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDT09_12855	COG3711	transcriptional antiterminator
DDT09_12855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDT09_12865	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DDT09_12870	COG0583	DNA-binding transcription factor activity
DDT09_12875	COG2814	Major facilitator Superfamily
DDT09_12880	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DDT09_12880	COG2124	cytochrome p450
DDT09_12885	COG1309	transcriptional regulator
DDT09_12890	COG2226	methyltransferase
DDT09_12905	COG2116	formate transmembrane transporter activity
DDT09_12910	COG5609	conserved protein (DUF2294)
DDT09_12915	COG3383	formate dehydrogenase (NAD+) activity
DDT09_12920	COG2427	Protein of unknown function (DUF1641)
DDT09_12930	COG0626	cystathionine gamma-synthase activity
DDT09_12935	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DDT09_12960	COG0768	penicillin binding
DDT09_12990	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DDT09_13005	COG4472	Bacterial protein of unknown function (DUF965)
DDT09_13015	COG0628	permease
DDT09_13020	COG1126	abc transporter atp-binding protein
DDT09_13025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDT09_13030	COG0765	amino acid transport
DDT09_13050	COG3881	PFAM PRC-barrel domain
DDT09_13055	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DDT09_13060	COG0457	Tetratricopeptide repeat
DDT09_13070	COG1104	cysteine desulfurase activity
DDT09_13075	COG1959	2 iron, 2 sulfur cluster binding
DDT09_13080	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DDT09_13085	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DDT09_13105	COG3103	Sh3 type 3 domain protein
DDT09_13105	COG0860	N-Acetylmuramoyl-L-alanine amidase
DDT09_13105	COG4991	sh3 domain protein
DDT09_13115	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DDT09_13125	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DDT09_13125	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DDT09_13130	COG5416	Lipopolysaccharide assembly protein A domain
DDT09_13135	COG0490	domain, Protein
DDT09_13140	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DDT09_13140	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DDT09_13150	COG2244	polysaccharide biosynthetic process
DDT09_13155	COG2323	membrane
DDT09_13165	COG1862	Preprotein translocase
DDT09_13210	COG1388	LysM domain
DDT09_13220	COG0157	Belongs to the NadC ModD family
DDT09_13225	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DDT09_13230	COG1104	cysteine desulfurase activity
DDT09_13235	COG1827	regulation of RNA biosynthetic process
DDT09_13240	COG0077	Prephenate dehydratase
DDT09_13255	COG3290	protein histidine kinase activity
DDT09_13260	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DDT09_13265	COG2868	ribosomal protein
DDT09_13275	COG1994	Peptidase M50
DDT09_13280	COG0739	heme binding
DDT09_13285	COG2894	cell division
DDT09_13295	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DDT09_13300	COG1792	Involved in formation and maintenance of cell shape
DDT09_13305	COG1077	Cell shape determining protein MreB Mrl
DDT09_13325	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DDT09_13330	COG0285	dihydrofolate synthase activity
DDT09_13335	COG0525	valine-tRNA ligase activity
DDT09_13345	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DDT09_13350	COG1388	LysM domain
DDT09_13360	COG0113	porphobilinogen synthase activity
DDT09_13365	COG1587	Uroporphyrinogen-III synthase
DDT09_13375	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DDT09_13395	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DDT09_13400	COG0470	DNA polymerase III
DDT09_13400	COG1067	ATP-dependent peptidase activity
DDT09_13415	COG0457	Tetratricopeptide repeat
DDT09_13415	COG1477	protein flavinylation
DDT09_13430	COG0473	3-isopropylmalate dehydrogenase activity
DDT09_13445	COG0440	acetolactate synthase activity
DDT09_13450	COG0028	Belongs to the TPP enzyme family
DDT09_13480	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
DDT09_13505	COG0622	Phosphoesterase
DDT09_13510	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DDT09_13520	COG5401	PFAM Sporulation and spore germination
DDT09_13530	COG1846	Transcriptional regulator
DDT09_13535	COG2197	response regulator
DDT09_13540	COG0824	Thioesterase
DDT09_13545	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DDT09_13550	COG1053	succinate dehydrogenase
DDT09_13555	COG2009	succinate dehydrogenase
DDT09_13560	COG1719	4-vinyl reductase, 4VR
DDT09_13565	COG0527	aspartate kinase activity
DDT09_13580	COG3118	belongs to the thioredoxin family
DDT09_13585	COG3534	alpha-L-arabinofuranosidase
DDT09_13590	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DDT09_13595	COG2086	electron transfer activity
DDT09_13600	COG1024	Enoyl-CoA hydratase
DDT09_13605	COG1309	transcriptional regulator
DDT09_13610	COG0318	PFAM AMP-dependent synthetase and ligase
DDT09_13625	COG3766	membrane
DDT09_13635	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DDT09_13635	COG1796	DNA polymerase
DDT09_13640	COG1286	toxin biosynthetic process
DDT09_13655	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DDT09_13655	COG0072	phenylalanine-tRNA ligase activity
DDT09_13660	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DDT09_13665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DDT09_13675	COG3835	regulator
DDT09_13680	COG0277	FAD linked oxidase domain protein
DDT09_13685	COG0247	lactate metabolic process
DDT09_13690	COG1966	Carbon starvation protein
DDT09_13695	COG3534	alpha-L-arabinofuranosidase
DDT09_13700	COG0395	ABC-type sugar transport system, permease component
DDT09_13705	COG1175	transmembrane transport
DDT09_13710	COG1653	transport
DDT09_13720	COG0647	UMP catabolic process
DDT09_13725	COG0235	Class ii aldolase
DDT09_13730	COG1069	ribulokinase activity
DDT09_13735	COG2160	L-arabinose isomerase activity
DDT09_13740	COG3507	Belongs to the glycosyl hydrolase 43 family
DDT09_13745	COG1363	Peptidase, m42
DDT09_13755	COG3326	Membrane
DDT09_13770	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DDT09_13775	COG1346	cytolysis
DDT09_13780	COG1380	Effector of murein hydrolase LrgA
DDT09_13785	COG3279	Response regulator of the LytR AlgR family
DDT09_13790	COG3275	phosphorelay sensor kinase activity
DDT09_13815	COG0398	Pfam SNARE associated Golgi protein
DDT09_13820	COG1484	DNA-dependent DNA replication
DDT09_13825	COG3611	Membrane attachment protein
DDT09_13840	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DDT09_13845	COG1733	regulation of RNA biosynthetic process
DDT09_13850	COG2814	Major facilitator Superfamily
DDT09_13855	COG0656	L-ascorbic acid biosynthetic process
DDT09_13860	COG0237	dephospho-CoA kinase activity
DDT09_13865	COG1971	Probably functions as a manganese efflux pump
DDT09_13870	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DDT09_13875	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DDT09_13875	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DDT09_13880	COG5002	protein histidine kinase activity
DDT09_13885	COG0745	RESPONSE REGULATOR receiver
DDT09_13895	COG0538	isocitrate dehydrogenase activity
DDT09_13900	COG0372	Belongs to the citrate synthase family
DDT09_13905	COG0457	Tetratricopeptide repeat
DDT09_13935	COG0628	permease
DDT09_13940	COG3030	protein affecting phage T7 exclusion by the F plasmid
DDT09_13945	COG0469	pyruvate kinase activity
DDT09_13965	COG0281	malic enzyme
DDT09_13970	COG0587	DNA-directed DNA polymerase activity
DDT09_13990	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DDT09_14000	COG4109	DRTGG domain
DDT09_14010	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_14025	COG0521	Mo-molybdopterin cofactor biosynthetic process
DDT09_14035	COG0827	DNA restriction-modification system
DDT09_14040	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DDT09_14045	COG3874	Sporulation protein YtfJ
DDT09_14055	COG1714	RDD family
DDT09_14060	COG0616	signal peptide processing
DDT09_14065	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DDT09_14070	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DDT09_14075	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DDT09_14090	COG1104	cysteine desulfurase activity
DDT09_14095	COG1114	Component of the transport system for branched-chain amino acids
DDT09_14105	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DDT09_14110	COG1309	transcriptional regulator
DDT09_14115	COG1956	GAF domain-containing protein
DDT09_14120	COG2203	Gaf domain
DDT09_14120	COG2199	diguanylate cyclase activity
DDT09_14135	COG1012	belongs to the aldehyde dehydrogenase family
DDT09_14140	COG4282	regulation of fungal-type cell wall biogenesis
DDT09_14195	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DDT09_14195	COG1017	nitric oxide dioxygenase activity
DDT09_14210	COG0693	protein deglycase activity
DDT09_14225	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DDT09_14230	COG1378	Sugar-specific transcriptional regulator TrmB
DDT09_14255	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DDT09_14260	COG0454	-acetyltransferase
DDT09_14265	COG0517	IMP dehydrogenase activity
DDT09_14270	COG0123	including yeast histone deacetylase and acetoin utilization protein
DDT09_14275	COG1360	Flagellar Motor Protein
DDT09_14280	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DDT09_14285	COG1609	Transcriptional regulator
DDT09_14290	COG1605	Chorismate mutase
DDT09_14290	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DDT09_14295	COG3118	belongs to the thioredoxin family
DDT09_14300	COG4980	gas vesicle protein
DDT09_14305	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DDT09_14315	COG1674	ftsk spoiiie
DDT09_14320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DDT09_14330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DDT09_14340	COG1363	Peptidase, m42
DDT09_14345	COG5584	Small secreted protein
DDT09_14350	COG0281	malic enzyme
DDT09_14355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DDT09_14370	COG0510	thiamine kinase activity
DDT09_14375	COG1597	lipid kinase activity
DDT09_14385	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DDT09_14390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DDT09_14395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DDT09_14400	COG2252	PERMEase
DDT09_14405	COG4473	ABC transporter
DDT09_14410	COG1131	(ABC) transporter
DDT09_14415	COG1349	DNA-binding transcription factor activity
DDT09_14420	COG1187	pseudouridine synthase activity
DDT09_14425	COG2244	polysaccharide biosynthetic process
DDT09_14430	COG2081	HI0933 family
DDT09_14435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DDT09_14465	COG1486	melibiose metabolic process
DDT09_14475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DDT09_14490	COG1366	Belongs to the anti-sigma-factor antagonist family
DDT09_14490	COG2202	Pas domain
DDT09_14495	COG2814	Major facilitator Superfamily
DDT09_14500	COG5522	Integral membrane protein (intg_mem_TP0381)
DDT09_14505	COG0577	efflux transmembrane transporter activity
DDT09_14510	COG1136	(ABC) transporter
DDT09_14515	COG2205	protein histidine kinase activity
DDT09_14520	COG0745	RESPONSE REGULATOR receiver
DDT09_14525	COG0577	efflux transmembrane transporter activity
DDT09_14530	COG1136	(ABC) transporter
DDT09_14550	COG1131	(ABC) transporter
DDT09_14555	COG1725	Transcriptional regulator
DDT09_14565	COG1242	4 iron, 4 sulfur cluster binding
DDT09_14570	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DDT09_14580	COG0584	glycerophosphoryl diester phosphodiesterase
DDT09_14590	COG2267	carboxylic ester hydrolase activity
DDT09_14595	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DDT09_14600	COG1113	amino acid transport
DDT09_14605	COG0367	asparagine synthase
DDT09_14625	COG1506	peptidase
DDT09_14630	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DDT09_14635	COG1116	anion transmembrane transporter activity
DDT09_14640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DDT09_14645	COG0494	nUDIX hydrolase
DDT09_14650	COG4824	toxin secretion phage lysis holin
DDT09_14655	COG0783	Belongs to the Dps family
DDT09_14680	COG0288	reversible hydration of carbon dioxide
DDT09_14690	COG1271	oxidase subunit
DDT09_14695	COG1294	oxidase, subunit
DDT09_14705	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DDT09_14710	COG1321	iron dependent repressor
DDT09_14710	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DDT09_14715	COG1121	(ABC) transporter
DDT09_14720	COG0803	Belongs to the bacterial solute-binding protein 9 family
DDT09_14725	COG4948	Mandelate Racemase Muconate Lactonizing
DDT09_14735	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DDT09_14740	COG0596	Alpha beta hydrolase
DDT09_14750	COG1169	isochorismate synthase
DDT09_14755	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DDT09_14760	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
DDT09_14885	COG3859	Proton-coupled thiamine transporter YuaJ
DDT09_14890	COG2268	Band 7 protein
DDT09_14895	COG1585	Membrane protein implicated in regulation of membrane protease activity
DDT09_14900	COG2318	DinB family
DDT09_14910	COG1454	alcohol dehydrogenase
DDT09_14920	COG1510	regulation of RNA biosynthetic process
DDT09_14930	COG0569	domain protein
DDT09_14935	COG1705	Flagellar rod assembly protein muramidase FlgJ
DDT09_14940	COG1017	nitric oxide dioxygenase activity
DDT09_14940	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DDT09_14965	COG0628	permease
DDT09_14970	COG0673	inositol 2-dehydrogenase activity
DDT09_14975	COG0693	protein deglycase activity
DDT09_14980	COG0840	transmembrane signaling receptor activity
DDT09_14985	COG0840	transmembrane signaling receptor activity
DDT09_14990	COG0840	transmembrane signaling receptor activity
DDT09_14995	COG0840	transmembrane signaling receptor activity
DDT09_15010	COG2070	2-Nitropropane dioxygenase
DDT09_15015	COG0432	Pfam Uncharacterised protein family UPF0047
DDT09_15020	COG0366	Alpha amylase catalytic
DDT09_15025	COG1253	flavin adenine dinucleotide binding
DDT09_15030	COG2738	Putative neutral zinc metallopeptidase
DDT09_15045	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DDT09_15075	COG1335	isochorismatase
DDT09_15080	COG1979	alcohol dehydrogenase
DDT09_15085	COG1979	alcohol dehydrogenase
DDT09_15090	COG2155	Conserved Protein
DDT09_15095	COG1098	S1 RNA binding domain
DDT09_15100	COG0436	Aminotransferase
DDT09_15105	COG1522	sequence-specific DNA binding
DDT09_15110	COG2267	carboxylic ester hydrolase activity
DDT09_15120	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DDT09_15125	COG2205	protein histidine kinase activity
DDT09_15135	COG5018	Exonuclease
DDT09_15140	COG2814	Major facilitator Superfamily
DDT09_15145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DDT09_15150	COG3011	Protein conserved in bacteria
DDT09_15160	COG3290	protein histidine kinase activity
DDT09_15165	COG4565	transcriptional regulatory protein
DDT09_15195	COG2111	Na H antiporter
DDT09_15195	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DDT09_15200	COG2111	Na H antiporter
DDT09_15205	COG1006	Multisubunit Na H antiporter MnhC subunit
DDT09_15210	COG0651	ATP synthesis coupled electron transport
DDT09_15215	COG1863	multisubunit Na H antiporter MnhE subunit
DDT09_15220	COG2212	antiporter activity
DDT09_15225	COG1320	monovalent cation:proton antiporter activity
DDT09_15230	COG2050	protein possibly involved in aromatic compounds catabolism
DDT09_15235	COG2197	response regulator
DDT09_15240	COG4585	Histidine kinase
DDT09_15250	COG0142	geranyltranstransferase activity
DDT09_15270	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DDT09_15275	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DDT09_15280	COG1335	isochorismatase
DDT09_15285	COG5506	Protein of unknown function (DUF1694)
DDT09_15300	COG0628	permease
DDT09_15310	COG1418	mRNA catabolic process
DDT09_15315	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_15325	COG1511	domain protein
DDT09_15330	COG1674	ftsk spoiiie
DDT09_15330	COG0433	COG0433 Predicted ATPase
DDT09_15335	COG4499	WXG100 protein secretion system (Wss), protein YukC
DDT09_15340	COG5417	Belongs to the EsaB family
DDT09_15345	COG4842	Belongs to the WXG100 family
DDT09_15350	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DDT09_15350	COG2508	Transcriptional regulator
DDT09_15355	COG0686	Belongs to the AlaDH PNT family
DDT09_15360	COG5634	Uncharacterized conserved protein (DUF2278)
DDT09_15365	COG3251	PFAM MbtH domain protein
DDT09_15370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDT09_15375	COG1535	isochorismatase
DDT09_15375	COG3433	isochorismatase activity
DDT09_15380	COG1021	2,3-dihydroxybenzoate-AMP ligase
DDT09_15385	COG1169	isochorismate synthase
DDT09_15390	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_15395	COG2819	hydrolase of the alpha beta superfamily
DDT09_15400	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DDT09_15405	COG1268	BioY protein
DDT09_15410	COG2056	Na+-H+ antiporter family
DDT09_15420	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
DDT09_15425	COG3584	3D domain protein
DDT09_15440	COG1252	NADH dehydrogenase
DDT09_15470	COG1131	(ABC) transporter
DDT09_15490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DDT09_15495	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
DDT09_15500	COG0316	Belongs to the HesB IscA family
DDT09_15510	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DDT09_15520	COG1252	NADH dehydrogenase
DDT09_15525	COG4837	Protein of unknown function (DUF1462)
DDT09_15530	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DDT09_15535	COG0823	Involved in the tonB-independent uptake of proteins
DDT09_15535	COG1506	peptidase
DDT09_15535	COG4946	Tricorn protease homolog
DDT09_15545	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DDT09_15550	COG0460	homoserine dehydrogenase
DDT09_15555	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DDT09_15560	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DDT09_15565	COG0647	UMP catabolic process
DDT09_15570	COG2445	Protein of unknown function DUF86
DDT09_15575	COG4470	Protein conserved in bacteria
DDT09_15590	COG0739	heme binding
DDT09_15600	COG0737	Belongs to the 5'-nucleotidase family
DDT09_15605	COG0730	response to heat
DDT09_15610	COG1801	Protein of unknown function DUF72
DDT09_15625	COG2508	Transcriptional regulator
DDT09_15645	COG2814	Major facilitator Superfamily
DDT09_15650	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DDT09_15655	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DDT09_15660	COG2356	endonuclease I
DDT09_15665	COG3842	ATPase activity
DDT09_15670	COG2188	Transcriptional regulator
DDT09_15675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDT09_15680	COG0395	ABC-type sugar transport system, permease component
DDT09_15685	COG1175	transmembrane transport
DDT09_15690	COG1653	transport
DDT09_15695	COG2222	sugar isomerase
DDT09_15700	COG0789	Transcriptional regulator
DDT09_15725	COG0322	excinuclease ABC activity
DDT09_15730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DDT09_15750	COG3409	Peptidoglycan-binding domain 1 protein
DDT09_15755	COG0719	Fe-S assembly protein
DDT09_15760	COG0822	iron-sulfur transferase activity
DDT09_15765	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DDT09_15770	COG0719	Fe-S assembly protein
DDT09_15775	COG0396	ATPase activity
DDT09_15785	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DDT09_15790	COG1464	Belongs to the NlpA lipoprotein family
DDT09_15795	COG2011	ABC-type metal ion transport system permease component
DDT09_15800	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DDT09_15810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DDT09_15815	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DDT09_15830	COG1393	Belongs to the ArsC family
DDT09_15835	COG1960	acyl-CoA dehydrogenase activity
DDT09_15840	COG0183	Belongs to the thiolase family
DDT09_15845	COG1250	3-hydroxyacyl-CoA dehydrogenase
DDT09_15845	COG1024	Enoyl-CoA hydratase
DDT09_15865	COG5577	PFAM Coat F domain
DDT09_15870	COG1846	Transcriptional regulator
DDT09_15875	COG0477	Major facilitator Superfamily
DDT09_15880	COG0583	DNA-binding transcription factor activity
DDT09_15900	COG1120	ATPase activity
DDT09_15915	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_15920	COG0783	Belongs to the Dps family
DDT09_15925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DDT09_15930	COG0745	RESPONSE REGULATOR receiver
DDT09_15935	COG2770	Histidine kinase
DDT09_15935	COG2205	protein histidine kinase activity
DDT09_15945	COG1309	transcriptional regulator
DDT09_15950	COG0114	fumarate hydratase activity
DDT09_15960	COG0697	spore germination
DDT09_15965	COG0814	amino acid
DDT09_15975	COG2197	response regulator
DDT09_15980	COG4585	Histidine kinase
DDT09_15985	COG4758	membrane
DDT09_15990	COG3595	metallopeptidase activity
DDT09_15995	COG1842	Phage shock protein A
DDT09_16000	COG4758	membrane
DDT09_16005	COG2814	Major facilitator Superfamily
DDT09_16010	COG2096	Adenosyltransferase
DDT09_16015	COG1120	ATPase activity
DDT09_16020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDT09_16025	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DDT09_16030	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_16035	COG3386	PFAM SMP-30 Gluconolaconase
DDT09_16040	COG2205	protein histidine kinase activity
DDT09_16045	COG0745	RESPONSE REGULATOR receiver
DDT09_16055	COG1191	sigma factor activity
DDT09_16065	COG2140	Oxalate decarboxylase
DDT09_16075	COG1120	ATPase activity
DDT09_16080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDT09_16085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDT09_16090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DDT09_16095	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DDT09_16100	COG0531	amino acid
DDT09_16115	COG1988	membrane-bound metal-dependent
DDT09_16120	COG1368	sulfuric ester hydrolase activity
DDT09_16125	COG1910	domain protein
DDT09_16130	COG0725	ABC transporter, periplasmic molybdate-binding protein
DDT09_16135	COG4149	molybdate abc transporter
DDT09_16140	COG2197	response regulator
DDT09_16145	COG3850	Histidine kinase
DDT09_16150	COG1131	(ABC) transporter
DDT09_16160	COG0842	Transport permease protein
DDT09_16165	COG0656	L-ascorbic acid biosynthetic process
DDT09_16190	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DDT09_16195	COG3973	AAA domain
DDT09_16200	COG2860	membrane
DDT09_16210	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DDT09_16215	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DDT09_16220	COG2217	Heavy metal translocating P-type atpase
DDT09_16225	COG2217	Heavy metal translocating P-type atpase
DDT09_16230	COG2608	mercury ion transmembrane transporter activity
DDT09_16235	COG1937	Protein conserved in bacteria
DDT09_16240	COG0673	inositol 2-dehydrogenase activity
DDT09_16250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDT09_16255	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DDT09_16260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDT09_16265	COG1126	abc transporter atp-binding protein
DDT09_16270	COG0765	amino acid transport
DDT09_16275	COG0765	amino acid transport
DDT09_16280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDT09_16285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDT09_16290	COG0454	-acetyltransferase
DDT09_16295	COG0583	DNA-binding transcription factor activity
DDT09_16300	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_16305	COG2732	(Barnase) inhibitor
DDT09_16320	COG0557	exoribonuclease II activity
DDT09_16325	COG1647	Serine aminopeptidase, S33
DDT09_16330	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DDT09_16335	COG1476	TRANSCRIPTIONal
DDT09_16340	COG1396	sequence-specific DNA binding
DDT09_16345	COG1396	sequence-specific DNA binding
DDT09_16350	COG1733	regulation of RNA biosynthetic process
DDT09_16380	COG1174	glycine betaine transport
DDT09_16385	COG1732	Glycine betaine
DDT09_16390	COG1174	glycine betaine transport
DDT09_16395	COG0517	IMP dehydrogenase activity
DDT09_16395	COG1125	glycine betaine transport
DDT09_16400	COG1510	regulation of RNA biosynthetic process
DDT09_16405	COG1174	glycine betaine transport
DDT09_16410	COG1732	Glycine betaine
DDT09_16415	COG1174	glycine betaine transport
DDT09_16420	COG0517	IMP dehydrogenase activity
DDT09_16420	COG1125	glycine betaine transport
DDT09_16425	COG1510	regulation of RNA biosynthetic process
DDT09_16430	COG2095	MarC family integral membrane protein
DDT09_16440	COG3064	Membrane
DDT09_16445	COG4640	response to antibiotic
DDT09_16450	COG0456	acetyltransferase
DDT09_16470	COG0126	phosphoglycerate kinase activity
DDT09_16480	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DDT09_16485	COG2390	Transcriptional regulator
DDT09_16490	COG2814	Major facilitator Superfamily
DDT09_16495	COG1609	Transcriptional regulator
DDT09_16500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDT09_16505	COG0583	DNA-binding transcription factor activity
DDT09_16510	COG0697	spore germination
DDT09_16515	COG1113	amino acid transport
DDT09_16520	COG1737	Transcriptional regulator
DDT09_16525	COG1070	Carbohydrate kinase
DDT09_16560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDT09_16565	COG2186	Transcriptional regulator
DDT09_16570	COG1620	l-lactate permease
DDT09_16575	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DDT09_16585	COG5039	Polysaccharide pyruvyl transferase
DDT09_16590	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DDT09_16595	COG0110	maltose O-acetyltransferase activity
DDT09_16600	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DDT09_16605	COG2244	polysaccharide biosynthetic process
DDT09_16610	COG1216	Glycosyl transferase, family 2
DDT09_16615	COG5039	Polysaccharide pyruvyl transferase
DDT09_16620	COG1216	Glycosyl transferase, family 2
DDT09_16630	COG0438	transferase activity, transferring glycosyl groups
DDT09_16635	COG1215	transferase activity, transferring glycosyl groups
DDT09_16640	COG0438	transferase activity, transferring glycosyl groups
DDT09_16645	COG1086	Polysaccharide biosynthesis protein
DDT09_16650	COG0489	protein tyrosine kinase activity
DDT09_16655	COG3944	biosynthesis protein
DDT09_16660	COG1396	sequence-specific DNA binding
DDT09_16665	COG2272	Belongs to the type-B carboxylesterase lipase family
DDT09_16675	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DDT09_16680	COG2364	Membrane
DDT09_16685	COG0456	acetyltransferase
DDT09_16690	COG3479	Phenolic acid decarboxylase
DDT09_16750	COG2223	nitrite transmembrane transporter activity
DDT09_16755	COG1609	Transcriptional regulator
DDT09_16765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DDT09_16770	COG0366	Alpha amylase catalytic
DDT09_16775	COG1554	hydrolase, family 65, central catalytic
DDT09_16780	COG5521	maltodextrose utilization protein MalA
DDT09_16785	COG3833	ABC-type maltose transport systems, permease component
DDT09_16790	COG1175	transmembrane transport
DDT09_16795	COG2182	Extracellular solute-binding protein
DDT09_16800	COG0366	Alpha amylase catalytic
DDT09_16805	COG1609	Transcriptional regulator
DDT09_16810	COG1611	Belongs to the LOG family
DDT09_16815	COG1694	Mazg nucleotide pyrophosphohydrolase
DDT09_16820	COG0659	secondary active sulfate transmembrane transporter activity
DDT09_16825	COG0288	reversible hydration of carbon dioxide
DDT09_16835	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DDT09_16840	COG4290	ribonuclease
DDT09_16845	COG2162	N-hydroxyarylamine O-acetyltransferase activity
DDT09_16850	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDT09_16855	COG1481	regulation of sporulation
DDT09_16860	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DDT09_16870	COG1051	belongs to the nudix hydrolase family
DDT09_16875	COG0492	ferredoxin-NADP+ reductase activity
DDT09_16880	COG3883	PFAM NLP P60 protein
DDT09_16880	COG0791	NLP P60 protein
DDT09_16885	COG0457	Tetratricopeptide repeat
DDT09_16890	COG5002	protein histidine kinase activity
DDT09_16895	COG0745	RESPONSE REGULATOR receiver
DDT09_16900	COG1132	(ABC) transporter
DDT09_16905	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DDT09_16905	COG0140	phosphoribosyl-ATP diphosphatase activity
DDT09_16930	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DDT09_16945	COG4990	cell redox homeostasis
DDT09_16950	COG0110	maltose O-acetyltransferase activity
DDT09_16970	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DDT09_16985	COG1309	transcriptional regulator
DDT09_16990	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DDT09_16995	COG1950	PFAM Membrane protein of
DDT09_17000	COG1983	PspC domain protein
DDT09_17005	COG3595	metallopeptidase activity
DDT09_17020	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DDT09_17030	COG4897	Protein conserved in bacteria
DDT09_17035	COG0574	Belongs to the PEP-utilizing enzyme family
DDT09_17035	COG3848	Pyruvate phosphate dikinase
DDT09_17040	COG1309	transcriptional regulator
DDT09_17045	COG2814	Major facilitator Superfamily
DDT09_17090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DDT09_17100	COG0793	Belongs to the peptidase S41A family
DDT09_17100	COG3409	Peptidoglycan-binding domain 1 protein
DDT09_17105	COG3420	alginic acid biosynthetic process
DDT09_17110	COG2177	Part of the ABC transporter FtsEX involved in
DDT09_17115	COG2884	Cell division ATP-binding protein ftsE
DDT09_17120	COG2010	Cytochrome c
DDT09_17125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DDT09_17140	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DDT09_17155	COG1516	flagellar protein fliS
DDT09_17160	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DDT09_17165	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DDT09_17185	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DDT09_17190	COG4786	Flagellar basal body rod
DDT09_17190	COG1256	bacterial-type flagellum assembly
DDT09_17195	COG3418	PFAM FlgN family protein
DDT09_17200	COG2747	anti-sigma28 factor FlgM
DDT09_17210	COG1040	competence protein
DDT09_17220	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DDT09_17225	COG1307	EDD domain protein, DegV family
DDT09_17230	COG2197	response regulator
DDT09_17235	COG4585	Histidine kinase
DDT09_17240	COG1739	Uncharacterized protein family UPF0029
DDT09_17245	COG1316	TRANSCRIPTIONal
DDT09_17250	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DDT09_17255	COG0438	transferase activity, transferring glycosyl groups
DDT09_17260	COG1215	transferase activity, transferring glycosyl groups
DDT09_17265	COG3206	protein involved in exopolysaccharide biosynthesis
DDT09_17270	COG3307	-O-antigen
DDT09_17275	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DDT09_17280	COG0297	glycogen (starch) synthase activity
DDT09_17280	COG0438	transferase activity, transferring glycosyl groups
DDT09_17285	COG2244	polysaccharide biosynthetic process
DDT09_17295	COG0860	N-Acetylmuramoyl-L-alanine amidase
DDT09_17295	COG2247	cell wall binding repeat
DDT09_17300	COG2247	cell wall binding repeat
DDT09_17300	COG2385	sporulation resulting in formation of a cellular spore
DDT09_17310	COG1316	TRANSCRIPTIONal
DDT09_17315	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DDT09_17320	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DDT09_17325	COG1134	teichoic acid transport
DDT09_17330	COG1682	transport, permease protein
DDT09_17335	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DDT09_17345	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DDT09_17350	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
DDT09_17355	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DDT09_17360	COG4193	domain, Protein
DDT09_17365	COG1482	cell wall glycoprotein biosynthetic process
DDT09_17370	COG0697	spore germination
DDT09_17375	COG0814	amino acid
DDT09_17385	COG1215	transferase activity, transferring glycosyl groups
DDT09_17390	COG2814	Major facilitator Superfamily
DDT09_17395	COG1316	TRANSCRIPTIONal
DDT09_17400	COG0561	phosphatase activity
DDT09_17405	COG2433	Pfam Transposase IS66
DDT09_17410	COG0791	NLP P60 protein
DDT09_17420	COG2843	Capsule synthesis protein
DDT09_17430	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DDT09_17440	COG0697	spore germination
DDT09_17445	COG0814	amino acid
DDT09_17455	COG1609	Transcriptional regulator
DDT09_17460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDT09_17470	COG1129	ABC transporter
DDT09_17475	COG1172	Belongs to the binding-protein-dependent transport system permease family
DDT09_17480	COG1879	ABC-type sugar transport system periplasmic component
DDT09_17485	COG3103	Sh3 type 3 domain protein
DDT09_17490	COG2249	NAD(P)H dehydrogenase (quinone) activity
DDT09_17495	COG3527	Alpha-acetolactate decarboxylase
DDT09_17500	COG0028	Belongs to the TPP enzyme family
DDT09_17505	COG0583	DNA-binding transcription factor activity
DDT09_17510	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DDT09_17525	COG5337	Spore coat protein CotH
DDT09_17535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DDT09_17545	COG0405	Gamma-glutamyltransferase
DDT09_17550	COG1522	sequence-specific DNA binding
DDT09_17555	COG2059	Chromate
DDT09_17560	COG2059	Chromate
DDT09_17570	COG0655	NAD(P)H dehydrogenase (quinone) activity
DDT09_17575	COG0583	DNA-binding transcription factor activity
DDT09_17625	COG5444	nuclease activity
DDT09_17645	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DDT09_17650	COG4464	protein tyrosine phosphatase activity
DDT09_17655	COG0489	protein tyrosine kinase activity
DDT09_17660	COG3944	biosynthesis protein
DDT09_17675	COG4715	Zinc finger, swim domain protein
DDT09_17680	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DDT09_17685	COG0561	phosphatase activity
DDT09_17690	COG1349	DNA-binding transcription factor activity
DDT09_17695	COG0629	single-stranded DNA binding
DDT09_17720	COG0457	Tetratricopeptide repeat
DDT09_17725	COG4786	Flagellar basal body rod
DDT09_17730	COG4786	Flagellar basal body rod
DDT09_17735	COG1077	Cell shape determining protein MreB Mrl
DDT09_17740	COG1609	Transcriptional regulator
DDT09_17745	COG1846	Transcriptional regulator
DDT09_17750	COG2814	Major facilitator Superfamily
DDT09_17755	COG1953	Uracil, thiamine, allantoin
DDT09_17760	COG0477	Major facilitator Superfamily
DDT09_17765	COG1335	isochorismatase
DDT09_17770	COG0004	ammonium transporteR
DDT09_17775	COG0347	Belongs to the P(II) protein family
DDT09_17780	COG0772	Belongs to the SEDS family
DDT09_17785	COG0671	phosphoesterase, PA-phosphatase related
DDT09_17795	COG0739	heme binding
DDT09_17800	COG1247	-acetyltransferase
DDT09_17815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DDT09_17825	COG0726	polysaccharide deacetylase
DDT09_17835	COG1959	2 iron, 2 sulfur cluster binding
DDT09_17850	COG0831	urea catabolic process
DDT09_17860	COG1994	Peptidase M50
DDT09_17865	COG0457	Tetratricopeptide repeat
DDT09_17875	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DDT09_17880	COG2304	oxidoreductase activity
DDT09_17885	COG2304	oxidoreductase activity
DDT09_17890	COG2385	sporulation resulting in formation of a cellular spore
DDT09_17895	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DDT09_17905	COG4836	Membrane
DDT09_17945	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DDT09_17975	COG0698	ribose 5-phosphate isomerase
DDT09_17980	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DDT09_17990	COG0009	L-threonylcarbamoyladenylate synthase
DDT09_17995	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DDT09_18015	COG2890	protein-(glutamine-N5) methyltransferase activity
DDT09_18020	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DDT09_18025	COG0346	lactoylglutathione lyase activity
DDT09_18030	COG0789	Transcriptional regulator
DDT09_18035	COG0679	Auxin Efflux Carrier
DDT09_18040	COG0281	malic enzyme
DDT09_18050	COG0254	rRNA binding
DDT09_18055	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DDT09_18060	COG1494	fructose-1,6-bisphosphatase
DDT09_18065	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DDT09_18075	COG0191	fructose-bisphosphate aldolase activity
DDT09_18080	COG2204	response regulator
DDT09_18085	COG4821	SIS domain
DDT09_18100	COG0247	lactate metabolic process
DDT09_18100	COG2181	nitrate reductase activity
DDT09_18105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DDT09_18120	COG1132	(ABC) transporter
DDT09_18125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DDT09_18135	COG2181	nitrate reductase activity
DDT09_18140	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DDT09_18145	COG1140	nitrate reductase beta subunit
DDT09_18150	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DDT09_18155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DDT09_18165	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DDT09_18170	COG2223	nitrite transmembrane transporter activity
DDT09_18180	COG4506	Protein conserved in bacteria
DDT09_18185	COG0457	Tetratricopeptide repeat
DDT09_18230	COG0010	Belongs to the arginase family
DDT09_18235	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DDT09_18240	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DDT09_18255	COG1994	Peptidase M50
DDT09_18260	COG1942	4-Oxalocrotonate Tautomerase
DDT09_18265	COG1846	Transcriptional regulator
DDT09_18275	COG0531	amino acid
DDT09_18280	COG3465	dGTPase activity
DDT09_18285	COG1078	dGTPase activity
DDT09_18300	COG1695	Transcriptional regulator
DDT09_18310	COG1131	(ABC) transporter
DDT09_18315	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DDT09_18345	COG0583	DNA-binding transcription factor activity
DDT09_18350	COG2855	membrane
DDT09_18355	COG0280	phosphate acetyltransferase
DDT09_18365	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_18370	COG0436	Aminotransferase
DDT09_18400	COG2814	Major facilitator Superfamily
DDT09_18405	COG2814	Major facilitator Superfamily
DDT09_18410	COG0833	amino acid
DDT09_18415	COG4187	Peptidase family M20/M25/M40
DDT09_18420	COG1012	belongs to the aldehyde dehydrogenase family
DDT09_18425	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DDT09_18430	COG2205	protein histidine kinase activity
DDT09_18450	COG1131	(ABC) transporter
DDT09_18455	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
DDT09_18460	COG1091	dTDP-4-dehydrorhamnose reductase activity
DDT09_18465	COG1088	dTDP-glucose 4,6-dehydratase activity
DDT09_18470	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DDT09_18475	COG3980	spore coat polysaccharide biosynthesis protein
DDT09_18480	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
DDT09_18485	COG2089	acid synthase
DDT09_18490	COG0456	acetyltransferase
DDT09_18495	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DDT09_18500	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DDT09_18505	COG0463	Glycosyl transferase, family 2
DDT09_18515	COG2363	Small membrane protein
DDT09_18520	COG2233	PERMEase
DDT09_18535	COG1216	Glycosyl transferase, family 2
DDT09_18550	COG1695	Transcriptional regulator
DDT09_18555	COG0351	phosphomethylpyrimidine kinase
DDT09_18565	COG1621	beta-fructofuranosidase activity
DDT09_18570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDT09_18570	COG1263	PTS System
DDT09_18575	COG3711	transcriptional antiterminator
DDT09_18585	COG1404	Belongs to the peptidase S8 family
DDT09_18590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDT09_18595	COG0778	Nitroreductase
DDT09_18600	COG0772	Belongs to the SEDS family
DDT09_18605	COG0454	-acetyltransferase
DDT09_18625	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DDT09_18630	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DDT09_18635	COG2261	transglycosylase associated protein
DDT09_18640	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DDT09_18645	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DDT09_18650	COG2246	polysaccharide biosynthetic process
DDT09_18655	COG1309	transcriptional regulator
DDT09_18675	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DDT09_18680	COG2837	iron assimilation
DDT09_18685	COG2822	iron ion transport
DDT09_18700	COG0583	DNA-binding transcription factor activity
DDT09_18710	COG1346	cytolysis
DDT09_18715	COG4895	conserved protein (DUF2196)
DDT09_18720	COG0789	Transcriptional regulator
DDT09_18725	COG5504	Zn-dependent protease
DDT09_18730	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DDT09_18735	COG0346	lactoylglutathione lyase activity
DDT09_18740	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDT09_18745	COG1404	Belongs to the peptidase S8 family
DDT09_18750	COG1442	glycosyl transferase family 8
DDT09_18755	COG1846	Transcriptional regulator
DDT09_18760	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DDT09_18765	COG2357	RelA SpoT domain protein
DDT09_18770	COG1575	Belongs to the MenA family. Type 1 subfamily
DDT09_18790	COG1696	Membrane protein involved in D-alanine export
DDT09_18800	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DDT09_18805	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DDT09_18810	COG1486	melibiose metabolic process
DDT09_18815	COG1447	Phosphotransferase system cellobiose-specific component IIA
DDT09_18820	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDT09_18825	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDT09_18830	COG3711	transcriptional antiterminator
DDT09_18830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDT09_18845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDT09_18850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDT09_18860	COG0640	Transcriptional regulator
DDT09_18865	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DDT09_18870	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDT09_18875	COG1447	Phosphotransferase system cellobiose-specific component IIA
DDT09_18880	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDT09_18885	COG2723	6-phospho-beta-galactosidase activity
DDT09_18890	COG1940	carbohydrate kinase activity
DDT09_18895	COG1482	cell wall glycoprotein biosynthetic process
DDT09_18905	COG0753	catalase activity
DDT09_18910	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
DDT09_18915	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DDT09_18920	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DDT09_18925	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DDT09_18930	COG4988	ABC transporter
DDT09_18935	COG1294	oxidase, subunit
DDT09_18940	COG1271	oxidase subunit
DDT09_18945	COG3493	citrate carrier protein
DDT09_18950	COG0726	polysaccharide deacetylase
DDT09_18955	COG3842	ATPase activity
DDT09_18960	COG2508	Transcriptional regulator
DDT09_18965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DDT09_18975	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DDT09_18985	COG4894	glucomannan catabolic process
DDT09_18990	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DDT09_18995	COG0500	methyltransferase
DDT09_19000	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DDT09_19020	COG0753	catalase activity
DDT09_19020	COG0693	protein deglycase activity
DDT09_19025	COG2851	Citrate transporter
DDT09_19030	COG2273	Hydrolase Family 16
DDT09_19035	COG3711	transcriptional antiterminator
DDT09_19040	COG2270	Major facilitator Superfamily
DDT09_19045	COG0513	Belongs to the DEAD box helicase family
DDT09_19055	COG0697	spore germination
DDT09_19060	COG0589	response to stress
DDT09_19070	COG0494	nUDIX hydrolase
DDT09_19075	COG3507	Belongs to the glycosyl hydrolase 43 family
DDT09_19100	COG0010	Belongs to the arginase family
DDT09_19105	COG0833	amino acid
DDT09_19110	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DDT09_19115	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DDT09_19125	COG2390	Transcriptional regulator
DDT09_19130	COG0561	phosphatase activity
DDT09_19160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DDT09_19165	COG5294	Protein conserved in bacteria
DDT09_19170	COG0577	efflux transmembrane transporter activity
DDT09_19175	COG1136	(ABC) transporter
DDT09_19180	COG2205	protein histidine kinase activity
DDT09_19185	COG0745	RESPONSE REGULATOR receiver
DDT09_19190	COG2205	protein histidine kinase activity
DDT09_19195	COG0745	RESPONSE REGULATOR receiver
DDT09_19225	COG1082	Xylose isomerase domain protein TIM barrel
DDT09_19235	COG2814	Major facilitator Superfamily
DDT09_19270	COG1349	DNA-binding transcription factor activity
DDT09_19275	COG0667	Aldo Keto reductase
DDT09_19280	COG2814	Major facilitator Superfamily
DDT09_19295	COG1028	Short-chain dehydrogenase reductase Sdr
DDT09_19300	COG2197	response regulator
DDT09_19305	COG4585	Histidine kinase
DDT09_19310	COG3239	Fatty acid desaturase
DDT09_19315	COG1309	transcriptional regulator
DDT09_19320	COG1012	belongs to the aldehyde dehydrogenase family
DDT09_19325	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DDT09_19335	COG0640	Transcriptional regulator
DDT09_19340	COG2814	Major facilitator Superfamily
DDT09_19345	COG1714	RDD family
DDT09_19355	COG0501	Belongs to the peptidase M48B family
DDT09_19360	COG1715	Restriction endonuclease
DDT09_19365	COG0450	alkyl hydroperoxide reductase
DDT09_19370	COG3634	alkyl hydroperoxide reductase activity
DDT09_19375	COG3177	Filamentation induced by cAMP protein fic
DDT09_19380	COG1113	amino acid transport
DDT09_19390	COG2080	2 iron, 2 sulfur cluster binding
DDT09_19405	COG2068	MobA-Related Protein
DDT09_19410	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DDT09_19465	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
DDT09_19470	COG0667	Aldo Keto reductase
DDT09_19475	COG0456	acetyltransferase
DDT09_19480	COG0457	Tetratricopeptide repeat
DDT09_19485	COG0010	Belongs to the arginase family
DDT09_19490	COG0833	amino acid
DDT09_19495	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DDT09_19500	COG3829	transcription factor binding
DDT09_19510	COG0488	(ABC) transporter
DDT09_19525	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DDT09_19530	COG5002	protein histidine kinase activity
DDT09_19530	COG3850	Histidine kinase
DDT09_19545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DDT09_19550	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DDT09_19555	COG4853	Protein conserved in bacteria
DDT09_19560	COG4863	YycH protein
DDT09_19565	COG5002	protein histidine kinase activity
DDT09_19570	COG0745	RESPONSE REGULATOR receiver
DDT09_19605	COG0346	lactoylglutathione lyase activity
DDT09_19610	COG0305	Participates in initiation and elongation during chromosome replication
DDT09_19630	COG3093	addiction module antidote protein HigA
DDT09_19635	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DDT09_19640	COG0297	glycogen (starch) synthase activity
DDT09_19650	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DDT09_19655	COG0438	transferase activity, transferring glycosyl groups
DDT09_19665	COG2112	serine threonine protein kinase
DDT09_19675	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
DDT09_19680	COG4241	membrane
DDT09_19690	COG5577	PFAM Coat F domain
DDT09_19695	COG1733	regulation of RNA biosynthetic process
DDT09_19705	COG0697	spore germination
DDT09_19710	COG1621	beta-fructofuranosidase activity
DDT09_19715	COG1621	beta-fructofuranosidase activity
DDT09_19720	COG1802	Transcriptional regulator
DDT09_19725	COG2318	DinB family
DDT09_19730	COG2211	Major facilitator Superfamily
DDT09_19735	COG0697	spore germination
DDT09_19740	COG0789	Transcriptional regulator
DDT09_19745	COG0583	DNA-binding transcription factor activity
DDT09_19755	COG2814	Major facilitator Superfamily
DDT09_19760	COG0583	DNA-binding transcription factor activity
DDT09_19770	COG0778	Nitroreductase
DDT09_19775	COG1846	Transcriptional regulator
DDT09_19780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DDT09_19785	COG1846	Transcriptional regulator
DDT09_19790	COG2153	protein acetylation
DDT09_19800	COG0546	phosphoglycolate phosphatase activity
DDT09_19810	COG0492	ferredoxin-NADP+ reductase activity
DDT09_19815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDT09_19820	COG0697	spore germination
DDT09_19855	COG1331	Highly conserved protein containing a thioredoxin domain
DDT09_19865	COG0457	Tetratricopeptide repeat
DDT09_19890	COG0741	lytic transglycosylase activity
DDT09_19890	COG0791	NLP P60 protein
DDT09_19895	COG5644	endopeptidase inhibitor activity
DDT09_19905	COG0433	COG0433 Predicted ATPase
DDT09_19955	COG2946	Replication initiation factor
DDT09_19960	COG1674	ftsk spoiiie
DDT09_19990	COG1396	sequence-specific DNA binding
DDT09_19995	COG2856	Zn peptidase
DDT09_20010	COG1331	Highly conserved protein containing a thioredoxin domain
DDT09_20015	COG1331	Highly conserved protein containing a thioredoxin domain
DDT09_20020	COG1266	CAAX protease self-immunity
DDT09_20025	COG0477	Major facilitator Superfamily
DDT09_20025	COG2814	Major facilitator Superfamily
DDT09_20030	COG0346	lactoylglutathione lyase activity
DDT09_20035	COG1609	Transcriptional regulator
DDT09_20040	COG0708	Exodeoxyribonuclease III
DDT09_20045	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DDT09_20050	COG2169	Transcriptional regulator
DDT09_20060	COG0629	single-stranded DNA binding
DDT09_20070	COG0012	GTP binding
DDT09_20075	COG0243	molybdopterin cofactor binding
DDT09_20080	COG4481	Protein conserved in bacteria
DDT09_20085	COG3949	Membrane
DDT09_20100	COG1475	DNA binding
DDT09_20105	COG1192	Involved in chromosome partitioning
DDT09_20130	COG1847	R3H domain protein
DDT09_20135	COG0706	membrane insertase activity
DDT09_20145	COG0230	Belongs to the bacterial ribosomal protein bL34 family