locus-tag	class	description
EXD81_00010	COG0646	methionine synthase
EXD81_00010	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXD81_00015	COG2153	protein acetylation
EXD81_00020	COG1357	PFAM Pentapeptide repeats (8 copies)
EXD81_00030	COG2318	DinB family
EXD81_00035	COG2207	Transcriptional regulator
EXD81_00035	COG1917	Cupin 2, conserved barrel domain protein
EXD81_00040	COG0534	Mate efflux family protein
EXD81_00045	COG1562	ergosterol biosynthetic process
EXD81_00070	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXD81_00110	COG1403	HNH endonuclease
EXD81_00135	COG2323	membrane
EXD81_00140	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXD81_00150	COG2814	Major facilitator Superfamily
EXD81_00155	COG3180	Ammonia monooxygenase
EXD81_00160	COG1846	Transcriptional regulator
EXD81_00165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXD81_00170	COG0681	Belongs to the peptidase S26 family
EXD81_00175	COG0398	Pfam SNARE associated Golgi protein
EXD81_00190	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXD81_00230	COG4903	ComK protein
EXD81_00240	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_00255	COG1268	BioY protein
EXD81_00265	COG0183	Belongs to the thiolase family
EXD81_00270	COG0406	alpha-ribazole phosphatase activity
EXD81_00305	COG0702	epimerase
EXD81_00310	COG0095	Lipoate-protein ligase
EXD81_00315	COG1234	tRNA 3'-trailer cleavage
EXD81_00325	COG1301	dicarboxylic acid transport
EXD81_00330	COG1363	Peptidase, m42
EXD81_00340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXD81_00345	COG1511	domain protein
EXD81_00350	COG1309	transcriptional regulator
EXD81_00370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXD81_00375	COG2329	Antibiotic biosynthesis monooxygenase
EXD81_00380	COG3069	C4-dicarboxylate transmembrane transporter activity
EXD81_00385	COG1473	amidohydrolase
EXD81_00395	COG4473	ABC transporter
EXD81_00400	COG1131	(ABC) transporter
EXD81_00405	COG0537	adenosine 5'-monophosphoramidase activity
EXD81_00410	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EXD81_00465	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXD81_00480	COG4717	serine-type aminopeptidase activity
EXD81_00485	COG0420	3'-5' exonuclease activity
EXD81_00490	COG1668	transmembrane transport
EXD81_00515	COG0490	domain, Protein
EXD81_00520	COG0475	glutathione-regulated potassium exporter activity
EXD81_00530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXD81_00535	COG0561	phosphatase activity
EXD81_00555	COG0189	ligase activity
EXD81_00580	COG0702	epimerase
EXD81_00585	COG1132	(ABC) transporter
EXD81_00590	COG1132	(ABC) transporter
EXD81_00595	COG0589	response to stress
EXD81_00610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXD81_00615	COG0726	polysaccharide deacetylase
EXD81_00620	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EXD81_00635	COG0584	glycerophosphoryl diester phosphodiesterase
EXD81_00640	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EXD81_00645	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EXD81_00650	COG1253	flavin adenine dinucleotide binding
EXD81_00655	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXD81_00660	COG0436	Aminotransferase
EXD81_00665	COG0789	Transcriptional regulator
EXD81_00670	COG1253	flavin adenine dinucleotide binding
EXD81_00675	COG0204	Acyl-transferase
EXD81_00680	COG1595	DNA-templated transcription, initiation
EXD81_00695	COG0733	neurotransmitter:sodium symporter activity
EXD81_00705	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_00710	COG0372	Belongs to the citrate synthase family
EXD81_00725	COG1785	Belongs to the alkaline phosphatase family
EXD81_00730	COG2719	SpoVR family
EXD81_00735	COG0668	transmembrane transport
EXD81_00745	COG1959	2 iron, 2 sulfur cluster binding
EXD81_00750	COG0791	NLP P60 protein
EXD81_00750	COG1388	LysM domain
EXD81_00765	COG0431	NADPH-dependent FMN reductase
EXD81_00770	COG2197	response regulator
EXD81_00775	COG2203	Gaf domain
EXD81_00775	COG4585	Histidine kinase
EXD81_00795	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXD81_00800	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXD81_00805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXD81_00810	COG3153	acetyltransferase
EXD81_00810	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXD81_00815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXD81_00820	COG0517	IMP dehydrogenase activity
EXD81_00830	COG0564	pseudouridine synthase activity
EXD81_00835	COG3764	Sortase (surface protein transpeptidase)
EXD81_00840	COG0737	Belongs to the 5'-nucleotidase family
EXD81_00840	COG1525	nuclease
EXD81_00840	COG4085	toxin activity
EXD81_00845	COG5577	PFAM Coat F domain
EXD81_00885	COG1278	Cold shock
EXD81_00890	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXD81_00895	COG1131	(ABC) transporter
EXD81_00900	COG1131	(ABC) transporter
EXD81_00905	COG1725	Transcriptional regulator
EXD81_00920	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXD81_00925	COG2814	Major facilitator Superfamily
EXD81_00930	COG1566	PFAM secretion protein HlyD family protein
EXD81_00935	COG1846	Transcriptional regulator
EXD81_00950	COG2766	serine protein kinase
EXD81_00955	COG1664	Polymer-forming cytoskeletal
EXD81_00960	COG1664	Polymer-forming cytoskeletal
EXD81_00965	COG0789	Transcriptional regulator
EXD81_00970	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXD81_00995	COG1476	TRANSCRIPTIONal
EXD81_01015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXD81_01020	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXD81_01025	COG1116	anion transmembrane transporter activity
EXD81_01040	COG0753	catalase activity
EXD81_01045	COG4608	Belongs to the ABC transporter superfamily
EXD81_01050	COG0444	Belongs to the ABC transporter superfamily
EXD81_01055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXD81_01060	COG0601	transmembrane transport
EXD81_01065	COG0747	negative chemotaxis
EXD81_01075	COG0277	FAD linked oxidase domain protein
EXD81_01085	COG3340	Belongs to the peptidase S51 family
EXD81_01090	COG1757	Na H antiporter
EXD81_01200	COG0735	belongs to the Fur family
EXD81_01205	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXD81_01215	COG4129	membrane
EXD81_01240	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_01255	COG1988	membrane-bound metal-dependent
EXD81_01260	COG4485	Bacterial membrane protein, YfhO
EXD81_01270	COG0596	Alpha beta hydrolase
EXD81_01275	COG5658	integral membrane protein
EXD81_01280	COG3103	Sh3 type 3 domain protein
EXD81_01295	COG3591	Belongs to the peptidase S1B family
EXD81_01320	COG1090	epimerase
EXD81_01335	COG0778	Nitroreductase
EXD81_01340	COG0384	phenazine biosynthesis protein PhzF
EXD81_01345	COG0392	lysyltransferase activity
EXD81_01345	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXD81_01350	COG1846	Transcriptional regulator
EXD81_01355	COG2814	Major facilitator Superfamily
EXD81_01360	COG2318	DinB family
EXD81_01365	COG2732	(Barnase) inhibitor
EXD81_01375	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EXD81_01385	COG1695	Transcriptional regulator
EXD81_01400	COG2514	catechol 2,3-dioxygenase activity
EXD81_01405	COG2259	Doxx family
EXD81_01410	COG1132	(ABC) transporter
EXD81_01415	COG1132	(ABC) transporter
EXD81_01420	COG5434	Belongs to the glycosyl hydrolase 28 family
EXD81_01430	COG1737	Transcriptional regulator
EXD81_01435	COG1486	melibiose metabolic process
EXD81_01445	COG3284	Transcriptional regulator
EXD81_01455	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXD81_01460	COG0022	dehydrogenase e1 component
EXD81_01465	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXD81_01470	COG4637	Psort location Cytoplasmic, score
EXD81_01475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXD81_01490	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EXD81_01495	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXD81_01500	COG0598	Magnesium transport protein CorA
EXD81_01510	COG2084	Dehydrogenase
EXD81_01515	COG0726	polysaccharide deacetylase
EXD81_01525	COG0535	radical SAM domain protein
EXD81_01540	COG0387	Pfam Sodium calcium exchanger
EXD81_01545	COG0477	Major facilitator Superfamily
EXD81_01550	COG1295	ribonuclease BN
EXD81_01555	COG4980	gas vesicle protein
EXD81_01560	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXD81_01570	COG2814	Major facilitator Superfamily
EXD81_01580	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXD81_01585	COG1609	Transcriptional regulator
EXD81_01590	COG0693	protein deglycase activity
EXD81_01610	COG0778	Nitroreductase
EXD81_01615	COG2188	Transcriptional regulator
EXD81_01620	COG0366	Alpha amylase catalytic
EXD81_01625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXD81_01625	COG1263	PTS System
EXD81_01640	COG0071	Belongs to the small heat shock protein (HSP20) family
EXD81_01650	COG1368	sulfuric ester hydrolase activity
EXD81_01660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXD81_01660	COG1263	PTS System
EXD81_01665	COG0024	Methionine aminopeptidase
EXD81_01685	COG2258	MOSC domain
EXD81_01695	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXD81_01700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXD81_01710	COG3181	Tripartite tricarboxylate transporter family receptor
EXD81_01715	COG4565	transcriptional regulatory protein
EXD81_01750	COG3866	Pectate lyase
EXD81_01770	COG0456	acetyltransferase
EXD81_01775	COG0513	Belongs to the DEAD box helicase family
EXD81_01785	COG2814	Major facilitator Superfamily
EXD81_01790	COG0789	Transcriptional regulator
EXD81_01795	COG0488	(ABC) transporter
EXD81_01800	COG0457	Tetratricopeptide repeat
EXD81_01800	COG0463	Glycosyl transferase, family 2
EXD81_01805	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_01810	COG0840	transmembrane signaling receptor activity
EXD81_01815	COG1012	belongs to the aldehyde dehydrogenase family
EXD81_01820	COG0531	amino acid
EXD81_01825	COG2223	nitrite transmembrane transporter activity
EXD81_01830	COG1442	glycosyl transferase family 8
EXD81_01835	COG1216	Glycosyl transferase, family 2
EXD81_01840	COG1442	glycosyl transferase family 8
EXD81_01845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXD81_01850	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXD81_01855	COG1368	sulfuric ester hydrolase activity
EXD81_01870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXD81_01875	COG1846	Transcriptional regulator
EXD81_01880	COG0670	Belongs to the BI1 family
EXD81_01885	COG0196	riboflavin kinase activity
EXD81_01890	COG5583	Uncharacterized small protein (DUF2292)
EXD81_01900	COG0346	lactoylglutathione lyase activity
EXD81_01905	COG2329	Antibiotic biosynthesis monooxygenase
EXD81_01910	COG2323	membrane
EXD81_01920	COG0454	-acetyltransferase
EXD81_01965	COG5444	nuclease activity
EXD81_02015	COG1131	(ABC) transporter
EXD81_02025	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EXD81_02030	COG1597	lipid kinase activity
EXD81_02035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXD81_02040	COG1309	transcriptional regulator
EXD81_02060	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXD81_02090	COG0210	DNA helicase
EXD81_02105	COG4496	protein, YerC YecD
EXD81_02110	COG1470	cell adhesion involved in biofilm formation
EXD81_02125	COG0151	Belongs to the GarS family
EXD81_02130	COG0138	bifunctional purine biosynthesis protein purh
EXD81_02135	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXD81_02145	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXD81_02160	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXD81_02170	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXD81_02175	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXD81_02180	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXD81_02205	COG2252	PERMEase
EXD81_02235	COG0714	Associated with various cellular activities
EXD81_02240	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXD81_02245	COG1113	amino acid transport
EXD81_02250	COG2132	Multicopper oxidase
EXD81_02260	COG0823	Involved in the tonB-independent uptake of proteins
EXD81_02265	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EXD81_02270	COG1063	alcohol dehydrogenase
EXD81_02275	COG1595	DNA-templated transcription, initiation
EXD81_02290	COG4260	virion core protein, lumpy skin disease virus
EXD81_02300	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXD81_02305	COG1842	Phage shock protein A
EXD81_02315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXD81_02325	COG1063	alcohol dehydrogenase
EXD81_02350	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXD81_02370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXD81_02385	COG0488	(ABC) transporter
EXD81_02395	COG0456	acetyltransferase
EXD81_02400	COG1214	PFAM Peptidase M22, glycoprotease
EXD81_02405	COG0802	atpase or kinase
EXD81_02450	COG2814	Major facilitator Superfamily
EXD81_02455	COG0604	alcohol dehydrogenase
EXD81_02460	COG3832	glyoxalase III activity
EXD81_02470	COG0531	amino acid
EXD81_02475	COG1309	transcriptional regulator
EXD81_02480	COG2076	Multidrug Resistance protein
EXD81_02485	COG2076	Multidrug Resistance protein
EXD81_02490	COG2807	transmembrane transport
EXD81_02495	COG2186	Transcriptional regulator
EXD81_02500	COG2188	Transcriptional regulator
EXD81_02505	COG2814	Major facilitator Superfamily
EXD81_02510	COG1388	LysM domain
EXD81_02515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXD81_02530	COG1819	glycosyl
EXD81_02550	COG1051	belongs to the nudix hydrolase family
EXD81_02560	COG0789	Transcriptional regulator
EXD81_02560	COG4978	Transcriptional regulator
EXD81_02565	COG0456	acetyltransferase
EXD81_02570	COG0730	response to heat
EXD81_02580	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXD81_02585	COG2814	Major facilitator Superfamily
EXD81_02595	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXD81_02600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXD81_02615	COG2409	Drug exporters of the RND superfamily
EXD81_02620	COG2197	response regulator
EXD81_02625	COG4585	Histidine kinase
EXD81_02635	COG5577	PFAM Coat F domain
EXD81_02640	COG1063	alcohol dehydrogenase
EXD81_02650	COG5577	PFAM Coat F domain
EXD81_02660	COG0697	spore germination
EXD81_02665	COG1309	transcriptional regulator
EXD81_02685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXD81_02695	COG0789	Transcriptional regulator
EXD81_02700	COG1064	alcohol dehydrogenase
EXD81_02725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXD81_02730	COG2318	DinB family
EXD81_02735	COG0662	Cupin 2, conserved barrel domain protein
EXD81_02760	COG0277	FAD linked oxidase domain protein
EXD81_02775	COG0662	Cupin 2, conserved barrel domain protein
EXD81_02785	COG3621	Patatin-like phospholipase
EXD81_02790	COG2271	Major facilitator Superfamily
EXD81_02815	COG0730	response to heat
EXD81_02820	COG0425	Belongs to the sulfur carrier protein TusA family
EXD81_02825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXD81_02825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXD81_02830	COG0425	Belongs to the sulfur carrier protein TusA family
EXD81_02830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXD81_02840	COG2210	Belongs to the sulfur carrier protein TusA family
EXD81_02845	COG1937	Protein conserved in bacteria
EXD81_02850	COG1329	Transcriptional regulator
EXD81_02855	COG1278	Cold shock
EXD81_02890	COG0351	phosphomethylpyrimidine kinase
EXD81_02925	COG1959	2 iron, 2 sulfur cluster binding
EXD81_02940	COG2030	dehydratase
EXD81_02950	COG1522	sequence-specific DNA binding
EXD81_02965	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXD81_02980	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EXD81_02995	COG1959	2 iron, 2 sulfur cluster binding
EXD81_03015	COG0604	alcohol dehydrogenase
EXD81_03080	COG0582	viral genome integration into host DNA
EXD81_03130	COG2183	response to ionizing radiation
EXD81_03135	COG2208	phosphoserine phosphatase activity
EXD81_03140	COG1191	sigma factor activity
EXD81_03150	COG1366	Belongs to the anti-sigma-factor antagonist family
EXD81_03160	COG2172	sigma factor antagonist activity
EXD81_03165	COG1366	Belongs to the anti-sigma-factor antagonist family
EXD81_03170	COG1366	Belongs to the anti-sigma-factor antagonist family
EXD81_03175	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXD81_03180	COG0864	Transcriptional regulator
EXD81_03185	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXD81_03190	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXD81_03200	COG0705	Rhomboid family
EXD81_03205	COG3428	Bacterial PH domain
EXD81_03210	COG3402	PFAM membrane-flanked domain
EXD81_03215	COG0513	Belongs to the DEAD box helicase family
EXD81_03220	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXD81_03230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXD81_03235	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXD81_03250	COG1960	acyl-CoA dehydrogenase activity
EXD81_03260	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXD81_03265	COG1131	(ABC) transporter
EXD81_03270	COG0628	permease
EXD81_03275	COG1301	dicarboxylic acid transport
EXD81_03280	COG4565	transcriptional regulatory protein
EXD81_03285	COG3290	protein histidine kinase activity
EXD81_03290	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EXD81_03295	COG3546	catalase activity
EXD81_03300	COG2329	Antibiotic biosynthesis monooxygenase
EXD81_03305	COG0662	Cupin 2, conserved barrel domain protein
EXD81_03310	COG3729	General stress protein
EXD81_03315	COG2217	Heavy metal translocating P-type atpase
EXD81_03320	COG2076	Multidrug Resistance protein
EXD81_03330	COG4876	unkown
EXD81_03345	COG1914	H( )-stimulated, divalent metal cation uptake system
EXD81_03385	COG0028	Belongs to the TPP enzyme family
EXD81_03390	COG0494	nUDIX hydrolase
EXD81_03395	COG0531	amino acid
EXD81_03405	COG1215	transferase activity, transferring glycosyl groups
EXD81_03415	COG3706	GGDEF domain
EXD81_03420	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXD81_03435	COG2814	Major facilitator Superfamily
EXD81_03445	COG3871	stress protein (general stress protein 26)
EXD81_03455	COG1917	Cupin 2, conserved barrel domain protein
EXD81_03460	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_03465	COG0318	PFAM AMP-dependent synthetase and ligase
EXD81_03470	COG3711	transcriptional antiterminator
EXD81_03475	COG4989	oxidoreductase activity
EXD81_03480	COG0768	penicillin binding
EXD81_03485	COG2329	Antibiotic biosynthesis monooxygenase
EXD81_03495	COG2755	lipolytic protein G-D-S-L family
EXD81_03500	COG1414	Transcriptional regulator
EXD81_03520	COG1914	H( )-stimulated, divalent metal cation uptake system
EXD81_03530	COG0561	phosphatase activity
EXD81_03540	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXD81_03550	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXD81_03565	COG1349	DNA-binding transcription factor activity
EXD81_03570	COG2372	response to copper ion
EXD81_03570	COG1276	copper resistance
EXD81_03575	COG4549	nuclear export factor GLE1
EXD81_03580	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_03585	COG4975	Glucose uptake
EXD81_03595	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXD81_03600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXD81_03605	COG0640	Transcriptional regulator
EXD81_03610	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EXD81_03615	COG0778	Nitroreductase
EXD81_03620	COG1309	transcriptional regulator
EXD81_03625	COG2814	Major facilitator Superfamily
EXD81_03635	COG4604	ABC transporter, ATP-binding protein
EXD81_03645	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXD81_03650	COG0527	aspartate kinase activity
EXD81_03665	COG0457	Tetratricopeptide repeat
EXD81_03680	COG0577	efflux transmembrane transporter activity
EXD81_03685	COG1136	(ABC) transporter
EXD81_03690	COG2079	MmgE PrpD family protein
EXD81_03700	COG1126	abc transporter atp-binding protein
EXD81_03705	COG0765	amino acid transport
EXD81_03710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXD81_03725	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EXD81_03735	COG0697	spore germination
EXD81_03745	COG5434	Belongs to the glycosyl hydrolase 28 family
EXD81_03750	COG3104	oligopeptide transport
EXD81_03765	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EXD81_03770	COG0163	prenyltransferase activity
EXD81_03775	COG0583	DNA-binding transcription factor activity
EXD81_03780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXD81_03785	COG0765	amino acid transport
EXD81_03790	COG1126	abc transporter atp-binding protein
EXD81_03800	COG2364	Membrane
EXD81_03815	COG0697	spore germination
EXD81_03825	COG2814	Major facilitator Superfamily
EXD81_03830	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EXD81_03835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXD81_03850	COG1733	regulation of RNA biosynthetic process
EXD81_03865	COG3209	COG3209 Rhs family protein
EXD81_03875	COG2723	6-phospho-beta-galactosidase activity
EXD81_03895	COG0523	cobalamin synthesis protein
EXD81_03900	COG2223	nitrite transmembrane transporter activity
EXD81_03905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXD81_03915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXD81_03920	COG2146	nitrite reductase [NAD(P)H] activity
EXD81_03935	COG2508	Transcriptional regulator
EXD81_03940	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXD81_03945	COG1012	belongs to the aldehyde dehydrogenase family
EXD81_03950	COG0506	proline dehydrogenase activity
EXD81_03955	COG3541	Predicted nucleotidyltransferase
EXD81_03960	COG3458	cephalosporin-C deacetylase activity
EXD81_03970	COG2271	Major facilitator Superfamily
EXD81_03975	COG1082	Xylose isomerase domain protein TIM barrel
EXD81_03980	COG1660	Displays ATPase and GTPase activities
EXD81_03995	COG3665	Urea carboxylase-associated protein
EXD81_04000	COG1113	amino acid transport
EXD81_04005	COG3403	YqcI/YcgG family
EXD81_04010	COG1280	lysine exporter protein (LysE YggA)
EXD81_04015	COG1846	Transcriptional regulator
EXD81_04020	COG2814	Major facilitator Superfamily
EXD81_04030	COG0366	Alpha amylase catalytic
EXD81_04040	COG1288	antiporter activity
EXD81_04045	COG1473	amidohydrolase
EXD81_04050	COG2113	Glycine betaine
EXD81_04055	COG4176	ABC-type proline glycine betaine transport system permease component
EXD81_04060	COG4175	Glycine betaine
EXD81_04060	COG0517	IMP dehydrogenase activity
EXD81_04065	COG0477	Major facilitator Superfamily
EXD81_04070	COG3853	Toxic anion resistance protein (TelA)
EXD81_04080	COG0861	Integral membrane protein TerC family
EXD81_04085	COG2310	stress, protein
EXD81_04090	COG2310	stress, protein
EXD81_04095	COG2310	stress, protein
EXD81_04100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXD81_04105	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXD81_04115	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXD81_04125	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_04130	COG0457	Tetratricopeptide repeat
EXD81_04135	COG1876	peptidase activity
EXD81_04140	COG1595	DNA-templated transcription, initiation
EXD81_04155	COG0667	Aldo Keto reductase
EXD81_04160	COG3012	SEC-C Motif Domain Protein
EXD81_04160	COG1405	negative regulation of cell septum assembly
EXD81_04165	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EXD81_04180	COG0477	Major facilitator Superfamily
EXD81_04185	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXD81_04195	COG0805	protein transport
EXD81_04200	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXD81_04205	COG3540	Alkaline phosphatase
EXD81_04215	COG3773	Cell wall hydrolase
EXD81_04230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXD81_04235	COG2259	Doxx family
EXD81_04240	COG0346	lactoylglutathione lyase activity
EXD81_04250	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXD81_04275	COG4191	Histidine kinase
EXD81_04280	COG2066	Belongs to the glutaminase family
EXD81_04285	COG1115	amino acid carrier protein
EXD81_04290	COG2040	homocysteine
EXD81_04305	COG1301	dicarboxylic acid transport
EXD81_04320	COG0688	phosphatidylethanolamine metabolic process
EXD81_04325	COG0586	Pfam SNARE associated Golgi protein
EXD81_04330	COG1183	phosphatidylcholine synthase activity
EXD81_04340	COG0371	Dehydrogenase
EXD81_04355	COG3409	Peptidoglycan-binding domain 1 protein
EXD81_04390	COG0584	glycerophosphoryl diester phosphodiesterase
EXD81_04405	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EXD81_04450	COG1131	(ABC) transporter
EXD81_04455	COG2197	response regulator
EXD81_04465	COG1011	Hydrolase
EXD81_04470	COG1113	amino acid transport
EXD81_04475	COG1846	Transcriptional regulator
EXD81_04480	COG1380	Effector of murein hydrolase LrgA
EXD81_04485	COG1346	cytolysis
EXD81_04530	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXD81_04540	COG1595	DNA-templated transcription, initiation
EXD81_04570	COG1683	Conserved Protein
EXD81_04575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXD81_04585	COG1263	PTS System
EXD81_04585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXD81_04600	COG3876	Protein conserved in bacteria
EXD81_04605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXD81_04605	COG2207	Transcriptional regulator
EXD81_04620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXD81_04625	COG2819	hydrolase of the alpha beta superfamily
EXD81_04630	COG0385	Bile acid
EXD81_04635	COG0659	secondary active sulfate transmembrane transporter activity
EXD81_04650	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXD81_04655	COG0738	Major facilitator superfamily
EXD81_04715	COG0726	polysaccharide deacetylase
EXD81_04720	COG2194	sulfuric ester hydrolase activity
EXD81_04730	COG0489	protein tyrosine kinase activity
EXD81_04735	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXD81_04750	COG2226	methyltransferase
EXD81_04775	COG1122	ATPase activity
EXD81_04780	COG1122	ATPase activity
EXD81_04805	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXD81_04810	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EXD81_04820	COG0024	Methionine aminopeptidase
EXD81_04840	COG1841	ribosomal large subunit assembly
EXD81_04890	COG0255	Belongs to the universal ribosomal protein uL29 family
EXD81_04895	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EXD81_04905	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXD81_04910	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXD81_04920	COG0089	rRNA binding
EXD81_04935	COG0051	transcription antitermination factor activity, RNA binding
EXD81_04940	COG0596	Alpha beta hydrolase
EXD81_04965	COG1358	cellular component organization or biogenesis
EXD81_04985	COG0222	ribosome binding
EXD81_05000	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXD81_05005	COG0250	Participates in transcription elongation, termination and antitermination
EXD81_05015	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXD81_05030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXD81_05035	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EXD81_05065	COG4956	integral membrane protein (PIN domain superfamily)
EXD81_05095	COG4463	regulation of RNA biosynthetic process
EXD81_05175	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EXD81_05185	COG1396	sequence-specific DNA binding
EXD81_05195	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXD81_05205	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXD81_05210	COG0512	Glutamine amidotransferase of anthranilate synthase
EXD81_05215	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXD81_05220	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXD81_05225	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXD81_05250	COG0037	tRNA processing
EXD81_05255	COG0515	serine threonine protein kinase
EXD81_05260	COG2304	oxidoreductase activity
EXD81_05280	COG1098	S1 RNA binding domain
EXD81_05285	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EXD81_05300	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXD81_05315	COG2002	toxin-antitoxin pair type II binding
EXD81_05320	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXD81_05340	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EXD81_05355	COG0251	oxidation-reduction process
EXD81_05360	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXD81_05375	COG4466	Protein conserved in bacteria
EXD81_05390	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXD81_05400	COG0084	hydrolase, TatD family'
EXD81_05410	COG2002	toxin-antitoxin pair type II binding
EXD81_05415	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXD81_05425	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXD81_05435	COG1774	PSP1 C-terminal conserved region
EXD81_05450	COG3870	Protein conserved in bacteria
EXD81_05460	COG1982	Orn Lys Arg decarboxylase major
EXD81_05465	COG3853	Toxic anion resistance protein (TelA)
EXD81_05470	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
EXD81_05525	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXD81_05535	COG0590	tRNA wobble adenosine to inosine editing
EXD81_05540	COG1335	isochorismatase
EXD81_05545	COG3858	chitin binding
EXD81_05545	COG1388	LysM domain
EXD81_05550	COG1428	Deoxynucleoside kinase
EXD81_05555	COG1428	Deoxynucleoside kinase
EXD81_05565	COG1929	Belongs to the glycerate kinase type-1 family
EXD81_05585	COG1686	Belongs to the peptidase S11 family
EXD81_05625	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXD81_05645	COG2501	S4 domain
EXD81_05650	COG0592	DNA-directed DNA polymerase activity
EXD81_05660	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXD81_05670	COG0706	membrane insertase activity
EXD81_05675	COG1847	R3H domain protein
EXD81_05700	COG1192	Involved in chromosome partitioning
EXD81_05720	COG3949	Membrane
EXD81_05725	COG4481	Protein conserved in bacteria
EXD81_05735	COG0012	GTP binding
EXD81_05745	COG0629	single-stranded DNA binding
EXD81_05755	COG2169	Transcriptional regulator
EXD81_05760	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXD81_05765	COG0708	Exodeoxyribonuclease III
EXD81_05770	COG1609	Transcriptional regulator
EXD81_05775	COG0346	lactoylglutathione lyase activity
EXD81_05785	COG1266	CAAX protease self-immunity
EXD81_05790	COG1331	Highly conserved protein containing a thioredoxin domain
EXD81_05795	COG0697	spore germination
EXD81_05805	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_05815	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXD81_05825	COG2153	protein acetylation
EXD81_05835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXD81_05840	COG1846	Transcriptional regulator
EXD81_05845	COG0778	Nitroreductase
EXD81_05855	COG0583	DNA-binding transcription factor activity
EXD81_05860	COG2814	Major facilitator Superfamily
EXD81_05870	COG0583	DNA-binding transcription factor activity
EXD81_05875	COG2211	Major facilitator Superfamily
EXD81_05885	COG1802	Transcriptional regulator
EXD81_05890	COG1621	beta-fructofuranosidase activity
EXD81_05915	COG5577	PFAM Coat F domain
EXD81_05930	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXD81_05950	COG0438	transferase activity, transferring glycosyl groups
EXD81_05965	COG0297	glycogen (starch) synthase activity
EXD81_05970	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EXD81_05975	COG3093	addiction module antidote protein HigA
EXD81_05995	COG0305	Participates in initiation and elongation during chromosome replication
EXD81_06000	COG0346	lactoylglutathione lyase activity
EXD81_06035	COG0745	RESPONSE REGULATOR receiver
EXD81_06040	COG5002	protein histidine kinase activity
EXD81_06045	COG4863	YycH protein
EXD81_06050	COG4853	Protein conserved in bacteria
EXD81_06055	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXD81_06070	COG5002	protein histidine kinase activity
EXD81_06070	COG3850	Histidine kinase
EXD81_06075	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXD81_06090	COG0488	(ABC) transporter
EXD81_06100	COG3829	transcription factor binding
EXD81_06105	COG0640	Transcriptional regulator
EXD81_06110	COG5658	integral membrane protein
EXD81_06115	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXD81_06120	COG0833	amino acid
EXD81_06125	COG0010	Belongs to the arginase family
EXD81_06130	COG0457	Tetratricopeptide repeat
EXD81_06135	COG0456	acetyltransferase
EXD81_06140	COG0667	Aldo Keto reductase
EXD81_06145	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EXD81_06240	COG2080	2 iron, 2 sulfur cluster binding
EXD81_06255	COG3634	alkyl hydroperoxide reductase activity
EXD81_06260	COG0450	alkyl hydroperoxide reductase
EXD81_06270	COG1714	RDD family
EXD81_06275	COG2814	Major facilitator Superfamily
EXD81_06280	COG0640	Transcriptional regulator
EXD81_06310	COG3239	Fatty acid desaturase
EXD81_06320	COG2197	response regulator
EXD81_06325	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_06340	COG2814	Major facilitator Superfamily
EXD81_06350	COG1349	DNA-binding transcription factor activity
EXD81_06390	COG1082	Xylose isomerase domain protein TIM barrel
EXD81_06420	COG0745	RESPONSE REGULATOR receiver
EXD81_06435	COG2205	protein histidine kinase activity
EXD81_06440	COG1136	(ABC) transporter
EXD81_06445	COG0577	efflux transmembrane transporter activity
EXD81_06450	COG5294	Protein conserved in bacteria
EXD81_06455	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXD81_06485	COG0561	phosphatase activity
EXD81_06490	COG2390	Transcriptional regulator
EXD81_06500	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXD81_06505	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXD81_06510	COG0833	amino acid
EXD81_06515	COG0010	Belongs to the arginase family
EXD81_06540	COG3507	Belongs to the glycosyl hydrolase 43 family
EXD81_06545	COG0494	nUDIX hydrolase
EXD81_06560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXD81_06560	COG1263	PTS System
EXD81_06560	COG2190	(PTS) system
EXD81_06565	COG2723	6-phospho-beta-galactosidase activity
EXD81_06570	COG0589	response to stress
EXD81_06625	COG0513	Belongs to the DEAD box helicase family
EXD81_06630	COG2270	Major facilitator Superfamily
EXD81_06635	COG3711	transcriptional antiterminator
EXD81_06640	COG2273	Hydrolase Family 16
EXD81_06670	COG0500	methyltransferase
EXD81_06675	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXD81_06680	COG4894	glucomannan catabolic process
EXD81_06690	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXD81_06700	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXD81_06705	COG2508	Transcriptional regulator
EXD81_06710	COG3842	ATPase activity
EXD81_06715	COG0726	polysaccharide deacetylase
EXD81_06720	COG3493	citrate carrier protein
EXD81_06725	COG1271	oxidase subunit
EXD81_06730	COG1294	oxidase, subunit
EXD81_06740	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXD81_06745	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EXD81_06755	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXD81_06760	COG0753	catalase activity
EXD81_06770	COG1482	cell wall glycoprotein biosynthetic process
EXD81_06775	COG1940	carbohydrate kinase activity
EXD81_06785	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXD81_06790	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXD81_06795	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXD81_06805	COG0640	Transcriptional regulator
EXD81_06815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXD81_06830	COG3711	transcriptional antiterminator
EXD81_06830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXD81_06835	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXD81_06840	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXD81_06850	COG1486	melibiose metabolic process
EXD81_06855	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXD81_06860	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXD81_06870	COG1696	Membrane protein involved in D-alanine export
EXD81_06890	COG1575	Belongs to the MenA family. Type 1 subfamily
EXD81_06895	COG2357	RelA SpoT domain protein
EXD81_06900	COG1442	glycosyl transferase family 8
EXD81_06905	COG1404	Belongs to the peptidase S8 family
EXD81_06910	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXD81_06915	COG0346	lactoylglutathione lyase activity
EXD81_06920	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXD81_06930	COG0789	Transcriptional regulator
EXD81_06935	COG4895	conserved protein (DUF2196)
EXD81_06940	COG1346	cytolysis
EXD81_06950	COG0583	DNA-binding transcription factor activity
EXD81_06965	COG2822	iron ion transport
EXD81_06970	COG2837	iron assimilation
EXD81_06975	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXD81_06995	COG1309	transcriptional regulator
EXD81_07000	COG2246	polysaccharide biosynthetic process
EXD81_07010	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EXD81_07015	COG2261	transglycosylase associated protein
EXD81_07020	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EXD81_07025	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXD81_07045	COG0454	-acetyltransferase
EXD81_07060	COG0778	Nitroreductase
EXD81_07065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXD81_07080	COG3711	transcriptional antiterminator
EXD81_07085	COG1263	PTS System
EXD81_07085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXD81_07090	COG1621	beta-fructofuranosidase activity
EXD81_07100	COG0351	phosphomethylpyrimidine kinase
EXD81_07105	COG1695	Transcriptional regulator
EXD81_07120	COG1216	Glycosyl transferase, family 2
EXD81_07140	COG2363	Small membrane protein
EXD81_07150	COG0463	Glycosyl transferase, family 2
EXD81_07160	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXD81_07165	COG0456	acetyltransferase
EXD81_07170	COG2089	acid synthase
EXD81_07175	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
EXD81_07180	COG3980	spore coat polysaccharide biosynthesis protein
EXD81_07185	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXD81_07190	COG1088	dTDP-glucose 4,6-dehydratase activity
EXD81_07195	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXD81_07200	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
EXD81_07210	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXD81_07215	COG1012	belongs to the aldehyde dehydrogenase family
EXD81_07225	COG0833	amino acid
EXD81_07265	COG0436	Aminotransferase
EXD81_07270	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_07280	COG0280	phosphate acetyltransferase
EXD81_07285	COG2855	membrane
EXD81_07290	COG0583	DNA-binding transcription factor activity
EXD81_07315	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXD81_07320	COG1131	(ABC) transporter
EXD81_07330	COG1695	Transcriptional regulator
EXD81_07345	COG1078	dGTPase activity
EXD81_07355	COG0531	amino acid
EXD81_07365	COG1846	Transcriptional regulator
EXD81_07370	COG1942	4-Oxalocrotonate Tautomerase
EXD81_07375	COG1994	Peptidase M50
EXD81_07390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXD81_07395	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXD81_07455	COG3391	amine dehydrogenase activity
EXD81_07460	COG3391	amine dehydrogenase activity
EXD81_07470	COG4506	Protein conserved in bacteria
EXD81_07480	COG2223	nitrite transmembrane transporter activity
EXD81_07495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXD81_07515	COG2181	nitrate reductase activity
EXD81_07545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXD81_07550	COG2181	nitrate reductase activity
EXD81_07550	COG0247	lactate metabolic process
EXD81_07565	COG4821	SIS domain
EXD81_07570	COG2204	response regulator
EXD81_07575	COG0191	fructose-bisphosphate aldolase activity
EXD81_07585	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EXD81_07600	COG0254	rRNA binding
EXD81_07610	COG0281	malic enzyme
EXD81_07615	COG0679	Auxin Efflux Carrier
EXD81_07620	COG0789	Transcriptional regulator
EXD81_07625	COG0346	lactoylglutathione lyase activity
EXD81_07630	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXD81_07655	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EXD81_07660	COG0009	L-threonylcarbamoyladenylate synthase
EXD81_07670	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXD81_07675	COG0698	ribose 5-phosphate isomerase
EXD81_07705	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EXD81_07745	COG4836	Membrane
EXD81_07755	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EXD81_07760	COG2385	sporulation resulting in formation of a cellular spore
EXD81_07770	COG2304	oxidoreductase activity
EXD81_07775	COG2304	oxidoreductase activity
EXD81_07780	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXD81_07790	COG0457	Tetratricopeptide repeat
EXD81_07795	COG1994	Peptidase M50
EXD81_07800	COG3237	CsbD-like
EXD81_07805	COG0831	urea catabolic process
EXD81_07820	COG1959	2 iron, 2 sulfur cluster binding
EXD81_07830	COG0726	polysaccharide deacetylase
EXD81_07860	COG1247	-acetyltransferase
EXD81_07865	COG0739	heme binding
EXD81_07875	COG0671	phosphoesterase, PA-phosphatase related
EXD81_07880	COG0772	Belongs to the SEDS family
EXD81_07885	COG0347	Belongs to the P(II) protein family
EXD81_07890	COG0004	ammonium transporteR
EXD81_07895	COG1335	isochorismatase
EXD81_07905	COG1953	Uracil, thiamine, allantoin
EXD81_07910	COG2814	Major facilitator Superfamily
EXD81_07915	COG1846	Transcriptional regulator
EXD81_07920	COG1609	Transcriptional regulator
EXD81_07925	COG1077	Cell shape determining protein MreB Mrl
EXD81_07930	COG4786	Flagellar basal body rod
EXD81_07935	COG4786	Flagellar basal body rod
EXD81_07940	COG0457	Tetratricopeptide repeat
EXD81_07965	COG0629	single-stranded DNA binding
EXD81_07970	COG1349	DNA-binding transcription factor activity
EXD81_07975	COG0561	phosphatase activity
EXD81_07985	COG4715	Zinc finger, swim domain protein
EXD81_08000	COG3944	biosynthesis protein
EXD81_08005	COG0489	protein tyrosine kinase activity
EXD81_08015	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXD81_08020	COG3878	Protein conserved in bacteria
EXD81_08085	COG2059	Chromate
EXD81_08090	COG2059	Chromate
EXD81_08095	COG1522	sequence-specific DNA binding
EXD81_08100	COG0405	Gamma-glutamyltransferase
EXD81_08110	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXD81_08120	COG5337	Spore coat protein CotH
EXD81_08135	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXD81_08140	COG0583	DNA-binding transcription factor activity
EXD81_08145	COG0028	Belongs to the TPP enzyme family
EXD81_08150	COG3527	Alpha-acetolactate decarboxylase
EXD81_08155	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXD81_08160	COG3103	Sh3 type 3 domain protein
EXD81_08165	COG1879	ABC-type sugar transport system periplasmic component
EXD81_08170	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXD81_08175	COG1129	ABC transporter
EXD81_08190	COG1609	Transcriptional regulator
EXD81_08200	COG0697	spore germination
EXD81_08210	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXD81_08225	COG0791	NLP P60 protein
EXD81_08235	COG0561	phosphatase activity
EXD81_08240	COG1316	TRANSCRIPTIONal
EXD81_08245	COG2814	Major facilitator Superfamily
EXD81_08250	COG1215	transferase activity, transferring glycosyl groups
EXD81_08260	COG0814	amino acid
EXD81_08265	COG0697	spore germination
EXD81_08270	COG1482	cell wall glycoprotein biosynthetic process
EXD81_08275	COG4193	domain, Protein
EXD81_08285	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EXD81_08305	COG1682	transport, permease protein
EXD81_08310	COG1134	teichoic acid transport
EXD81_08350	COG2244	polysaccharide biosynthetic process
EXD81_08355	COG0297	glycogen (starch) synthase activity
EXD81_08355	COG0438	transferase activity, transferring glycosyl groups
EXD81_08360	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXD81_08365	COG3307	-O-antigen
EXD81_08370	COG3206	protein involved in exopolysaccharide biosynthesis
EXD81_08375	COG1215	transferase activity, transferring glycosyl groups
EXD81_08380	COG0438	transferase activity, transferring glycosyl groups
EXD81_08385	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXD81_08390	COG1316	TRANSCRIPTIONal
EXD81_08400	COG4585	Histidine kinase
EXD81_08405	COG2197	response regulator
EXD81_08410	COG1307	EDD domain protein, DegV family
EXD81_08415	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXD81_08425	COG1040	competence protein
EXD81_08440	COG3418	PFAM FlgN family protein
EXD81_08445	COG1256	bacterial-type flagellum assembly
EXD81_08445	COG4786	Flagellar basal body rod
EXD81_08450	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXD81_08470	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXD81_08475	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EXD81_08480	COG1516	flagellar protein fliS
EXD81_08495	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EXD81_08520	COG2884	Cell division ATP-binding protein ftsE
EXD81_08560	COG2814	Major facilitator Superfamily
EXD81_08565	COG1309	transcriptional regulator
EXD81_08570	COG3848	Pyruvate phosphate dikinase
EXD81_08570	COG0574	Belongs to the PEP-utilizing enzyme family
EXD81_08575	COG4897	Protein conserved in bacteria
EXD81_08585	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXD81_08600	COG3595	metallopeptidase activity
EXD81_08605	COG1983	PspC domain protein
EXD81_08610	COG1950	PFAM Membrane protein of
EXD81_08620	COG1309	transcriptional regulator
EXD81_08655	COG0110	maltose O-acetyltransferase activity
EXD81_08660	COG4990	cell redox homeostasis
EXD81_08675	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EXD81_08700	COG0140	phosphoribosyl-ATP diphosphatase activity
EXD81_08700	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EXD81_08705	COG1132	(ABC) transporter
EXD81_08710	COG0745	RESPONSE REGULATOR receiver
EXD81_08715	COG5002	protein histidine kinase activity
EXD81_08720	COG0457	Tetratricopeptide repeat
EXD81_08730	COG0492	ferredoxin-NADP+ reductase activity
EXD81_08745	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXD81_08755	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXD81_08760	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXD81_08765	COG4290	ribonuclease
EXD81_08770	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXD81_08780	COG0288	reversible hydration of carbon dioxide
EXD81_08785	COG0659	secondary active sulfate transmembrane transporter activity
EXD81_08795	COG1611	Belongs to the LOG family
EXD81_08800	COG1609	Transcriptional regulator
EXD81_08805	COG0366	Alpha amylase catalytic
EXD81_08810	COG2182	Extracellular solute-binding protein
EXD81_08815	COG1175	transmembrane transport
EXD81_08820	COG3833	ABC-type maltose transport systems, permease component
EXD81_08825	COG5521	maltodextrose utilization protein MalA
EXD81_08830	COG1554	hydrolase, family 65, central catalytic
EXD81_08840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXD81_08850	COG1609	Transcriptional regulator
EXD81_08855	COG2223	nitrite transmembrane transporter activity
EXD81_08905	COG3479	Phenolic acid decarboxylase
EXD81_08910	COG0456	acetyltransferase
EXD81_08915	COG2364	Membrane
EXD81_08920	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXD81_08925	COG2272	Belongs to the type-B carboxylesterase lipase family
EXD81_08930	COG1396	sequence-specific DNA binding
EXD81_08940	COG0489	protein tyrosine kinase activity
EXD81_08945	COG1086	Polysaccharide biosynthesis protein
EXD81_08950	COG0438	transferase activity, transferring glycosyl groups
EXD81_08955	COG1215	transferase activity, transferring glycosyl groups
EXD81_08960	COG0438	transferase activity, transferring glycosyl groups
EXD81_08970	COG1216	Glycosyl transferase, family 2
EXD81_08975	COG5039	Polysaccharide pyruvyl transferase
EXD81_08990	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXD81_08995	COG0110	maltose O-acetyltransferase activity
EXD81_09000	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXD81_09005	COG5039	Polysaccharide pyruvyl transferase
EXD81_09015	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXD81_09020	COG1620	l-lactate permease
EXD81_09025	COG2186	Transcriptional regulator
EXD81_09030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXD81_09055	COG1070	Carbohydrate kinase
EXD81_09060	COG1737	Transcriptional regulator
EXD81_09070	COG0697	spore germination
EXD81_09085	COG1609	Transcriptional regulator
EXD81_09095	COG2390	Transcriptional regulator
EXD81_09100	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXD81_09140	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXD81_09145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXD81_09165	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXD81_09190	COG3064	Membrane
EXD81_09195	COG2095	MarC family integral membrane protein
EXD81_09200	COG1510	regulation of RNA biosynthetic process
EXD81_09205	COG0517	IMP dehydrogenase activity
EXD81_09205	COG1125	glycine betaine transport
EXD81_09210	COG1174	glycine betaine transport
EXD81_09215	COG1732	Glycine betaine
EXD81_09220	COG1174	glycine betaine transport
EXD81_09225	COG1510	regulation of RNA biosynthetic process
EXD81_09230	COG0517	IMP dehydrogenase activity
EXD81_09230	COG1125	glycine betaine transport
EXD81_09235	COG1174	glycine betaine transport
EXD81_09240	COG1732	Glycine betaine
EXD81_09245	COG1174	glycine betaine transport
EXD81_09275	COG1733	regulation of RNA biosynthetic process
EXD81_09280	COG1396	sequence-specific DNA binding
EXD81_09285	COG1396	sequence-specific DNA binding
EXD81_09290	COG1476	TRANSCRIPTIONal
EXD81_09295	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXD81_09300	COG1647	Serine aminopeptidase, S33
EXD81_09305	COG0557	exoribonuclease II activity
EXD81_09320	COG2732	(Barnase) inhibitor
EXD81_09325	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_09330	COG0583	DNA-binding transcription factor activity
EXD81_09335	COG0454	-acetyltransferase
EXD81_09340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXD81_09355	COG0765	amino acid transport
EXD81_09360	COG1126	abc transporter atp-binding protein
EXD81_09365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXD81_09370	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EXD81_09375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXD81_09385	COG0673	inositol 2-dehydrogenase activity
EXD81_09390	COG1937	Protein conserved in bacteria
EXD81_09395	COG2608	mercury ion transmembrane transporter activity
EXD81_09410	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXD81_09415	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EXD81_09425	COG2860	membrane
EXD81_09435	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EXD81_09460	COG0656	L-ascorbic acid biosynthetic process
EXD81_09465	COG0842	Transport permease protein
EXD81_09475	COG1131	(ABC) transporter
EXD81_09480	COG3850	Histidine kinase
EXD81_09485	COG2197	response regulator
EXD81_09490	COG4149	molybdate abc transporter
EXD81_09495	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXD81_09500	COG1910	domain protein
EXD81_09510	COG1988	membrane-bound metal-dependent
EXD81_09525	COG0531	amino acid
EXD81_09530	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXD81_09535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXD81_09545	COG1120	ATPase activity
EXD81_09555	COG2140	Oxalate decarboxylase
EXD81_09565	COG1191	sigma factor activity
EXD81_09575	COG0745	RESPONSE REGULATOR receiver
EXD81_09585	COG3386	PFAM SMP-30 Gluconolaconase
EXD81_09590	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_09595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXD81_09600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXD81_09605	COG1120	ATPase activity
EXD81_09610	COG2096	Adenosyltransferase
EXD81_09615	COG2814	Major facilitator Superfamily
EXD81_09620	COG4758	membrane
EXD81_09625	COG1842	Phage shock protein A
EXD81_09630	COG3595	metallopeptidase activity
EXD81_09635	COG4758	membrane
EXD81_09640	COG4585	Histidine kinase
EXD81_09645	COG2197	response regulator
EXD81_09655	COG0814	amino acid
EXD81_09660	COG0697	spore germination
EXD81_09675	COG1309	transcriptional regulator
EXD81_09685	COG2770	Histidine kinase
EXD81_09685	COG2205	protein histidine kinase activity
EXD81_09690	COG0745	RESPONSE REGULATOR receiver
EXD81_09710	COG0783	Belongs to the Dps family
EXD81_09730	COG1120	ATPase activity
EXD81_09750	COG0583	DNA-binding transcription factor activity
EXD81_09760	COG1846	Transcriptional regulator
EXD81_09765	COG5577	PFAM Coat F domain
EXD81_09790	COG0183	Belongs to the thiolase family
EXD81_09795	COG1960	acyl-CoA dehydrogenase activity
EXD81_09800	COG1393	Belongs to the ArsC family
EXD81_09820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXD81_09830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EXD81_09835	COG2011	ABC-type metal ion transport system permease component
EXD81_09840	COG1464	Belongs to the NlpA lipoprotein family
EXD81_09845	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXD81_09855	COG0396	ATPase activity
EXD81_09860	COG0719	Fe-S assembly protein
EXD81_09865	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXD81_09870	COG0822	iron-sulfur transferase activity
EXD81_09875	COG0719	Fe-S assembly protein
EXD81_09880	COG3409	Peptidoglycan-binding domain 1 protein
EXD81_09895	COG2226	methyltransferase
EXD81_09900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXD81_09905	COG0322	excinuclease ABC activity
EXD81_09915	COG2222	sugar isomerase
EXD81_09925	COG1175	transmembrane transport
EXD81_09930	COG0395	ABC-type sugar transport system, permease component
EXD81_09935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXD81_09940	COG2188	Transcriptional regulator
EXD81_09950	COG2356	endonuclease I
EXD81_09955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXD81_09960	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXD81_09965	COG2814	Major facilitator Superfamily
EXD81_09970	COG2369	cell adhesion
EXD81_09990	COG2508	Transcriptional regulator
EXD81_10005	COG1801	Protein of unknown function DUF72
EXD81_10015	COG0737	Belongs to the 5'-nucleotidase family
EXD81_10025	COG0739	heme binding
EXD81_10040	COG4470	Protein conserved in bacteria
EXD81_10045	COG2445	Protein of unknown function DUF86
EXD81_10050	COG0647	UMP catabolic process
EXD81_10060	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXD81_10065	COG0460	homoserine dehydrogenase
EXD81_10070	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EXD81_10080	COG0823	Involved in the tonB-independent uptake of proteins
EXD81_10080	COG1506	peptidase
EXD81_10080	COG4946	Tricorn protease homolog
EXD81_10085	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXD81_10090	COG4837	Protein of unknown function (DUF1462)
EXD81_10095	COG1252	NADH dehydrogenase
EXD81_10115	COG0316	Belongs to the HesB IscA family
EXD81_10175	COG1252	NADH dehydrogenase
EXD81_10190	COG3584	3D domain protein
EXD81_10205	COG2056	Na+-H+ antiporter family
EXD81_10215	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXD81_10220	COG2819	hydrolase of the alpha beta superfamily
EXD81_10225	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_10230	COG1169	isochorismate synthase
EXD81_10235	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXD81_10240	COG1535	isochorismatase
EXD81_10240	COG3433	isochorismatase activity
EXD81_10250	COG3251	PFAM MbtH domain protein
EXD81_10255	COG5634	Uncharacterized conserved protein (DUF2278)
EXD81_10260	COG0686	Belongs to the AlaDH PNT family
EXD81_10265	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXD81_10265	COG2508	Transcriptional regulator
EXD81_10270	COG4842	Belongs to the WXG100 family
EXD81_10275	COG5417	Belongs to the EsaB family
EXD81_10285	COG1674	ftsk spoiiie
EXD81_10285	COG0433	COG0433 Predicted ATPase
EXD81_10300	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_10305	COG1418	mRNA catabolic process
EXD81_10330	COG5506	Protein of unknown function (DUF1694)
EXD81_10335	COG1335	isochorismatase
EXD81_10380	COG2197	response regulator
EXD81_10385	COG2050	protein possibly involved in aromatic compounds catabolism
EXD81_10390	COG1320	monovalent cation:proton antiporter activity
EXD81_10395	COG2212	antiporter activity
EXD81_10400	COG1863	multisubunit Na H antiporter MnhE subunit
EXD81_10405	COG0651	ATP synthesis coupled electron transport
EXD81_10415	COG2111	Na H antiporter
EXD81_10420	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXD81_10420	COG2111	Na H antiporter
EXD81_10450	COG4565	transcriptional regulatory protein
EXD81_10455	COG3290	protein histidine kinase activity
EXD81_10465	COG3011	Protein conserved in bacteria
EXD81_10470	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXD81_10480	COG5018	Exonuclease
EXD81_10505	COG2267	carboxylic ester hydrolase activity
EXD81_10510	COG1522	sequence-specific DNA binding
EXD81_10515	COG0436	Aminotransferase
EXD81_10520	COG1098	S1 RNA binding domain
EXD81_10525	COG2155	Conserved Protein
EXD81_10530	COG1979	alcohol dehydrogenase
EXD81_10570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXD81_10585	COG2738	Putative neutral zinc metallopeptidase
EXD81_10590	COG1253	flavin adenine dinucleotide binding
EXD81_10595	COG0366	Alpha amylase catalytic
EXD81_10600	COG0432	Pfam Uncharacterised protein family UPF0047
EXD81_10605	COG2070	2-Nitropropane dioxygenase
EXD81_10625	COG0840	transmembrane signaling receptor activity
EXD81_10630	COG0840	transmembrane signaling receptor activity
EXD81_10635	COG0840	transmembrane signaling receptor activity
EXD81_10640	COG0693	protein deglycase activity
EXD81_10645	COG0673	inositol 2-dehydrogenase activity
EXD81_10650	COG0628	permease
EXD81_10665	COG0582	viral genome integration into host DNA
EXD81_10670	COG2856	Zn peptidase
EXD81_10680	COG3620	sequence-specific DNA binding
EXD81_10735	COG3935	DnaD domain protein
EXD81_10740	COG1484	DNA-dependent DNA replication
EXD81_10745	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
EXD81_10795	COG1595	DNA-templated transcription, initiation
EXD81_10945	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXD81_10945	COG3409	Peptidoglycan-binding domain 1 protein
EXD81_10945	COG1388	LysM domain
EXD81_10995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EXD81_10995	COG1017	nitric oxide dioxygenase activity
EXD81_11000	COG1705	Flagellar rod assembly protein muramidase FlgJ
EXD81_11005	COG0569	domain protein
EXD81_11015	COG1510	regulation of RNA biosynthetic process
EXD81_11035	COG2318	DinB family
EXD81_11040	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXD81_11050	COG3859	Proton-coupled thiamine transporter YuaJ
EXD81_11175	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
EXD81_11180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXD81_11200	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXD81_11225	COG1294	oxidase, subunit
EXD81_11230	COG1271	oxidase subunit
EXD81_11240	COG0288	reversible hydration of carbon dioxide
EXD81_11265	COG0783	Belongs to the Dps family
EXD81_11275	COG0494	nUDIX hydrolase
EXD81_11280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXD81_11285	COG1116	anion transmembrane transporter activity
EXD81_11290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXD81_11315	COG0367	asparagine synthase
EXD81_11330	COG2267	carboxylic ester hydrolase activity
EXD81_11345	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXD81_11360	COG1725	Transcriptional regulator
EXD81_11365	COG1131	(ABC) transporter
EXD81_11380	COG1136	(ABC) transporter
EXD81_11385	COG0577	efflux transmembrane transporter activity
EXD81_11390	COG0745	RESPONSE REGULATOR receiver
EXD81_11395	COG2205	protein histidine kinase activity
EXD81_11400	COG1136	(ABC) transporter
EXD81_11405	COG0577	efflux transmembrane transporter activity
EXD81_11415	COG2814	Major facilitator Superfamily
EXD81_11420	COG2202	Pas domain
EXD81_11420	COG1366	Belongs to the anti-sigma-factor antagonist family
EXD81_11435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXD81_11445	COG1486	melibiose metabolic process
EXD81_11470	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXD81_11480	COG2244	polysaccharide biosynthetic process
EXD81_11485	COG1187	pseudouridine synthase activity
EXD81_11490	COG1349	DNA-binding transcription factor activity
EXD81_11495	COG1131	(ABC) transporter
EXD81_11500	COG4473	ABC transporter
EXD81_11515	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXD81_11520	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXD81_11530	COG1597	lipid kinase activity
EXD81_11535	COG0510	thiamine kinase activity
EXD81_11550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXD81_11555	COG0281	malic enzyme
EXD81_11560	COG5584	Small secreted protein
EXD81_11565	COG1363	Peptidase, m42
EXD81_11575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXD81_11585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXD81_11590	COG1674	ftsk spoiiie
EXD81_11600	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EXD81_11610	COG3118	belongs to the thioredoxin family
EXD81_11615	COG1605	Chorismate mutase
EXD81_11615	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXD81_11620	COG1609	Transcriptional regulator
EXD81_11625	COG1609	Transcriptional regulator
EXD81_11630	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXD81_11635	COG1360	Flagellar Motor Protein
EXD81_11640	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXD81_11645	COG0517	IMP dehydrogenase activity
EXD81_11650	COG0454	-acetyltransferase
EXD81_11655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXD81_11680	COG1378	Sugar-specific transcriptional regulator TrmB
EXD81_11700	COG0693	protein deglycase activity
EXD81_11710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EXD81_11710	COG1017	nitric oxide dioxygenase activity
EXD81_11735	COG1595	DNA-templated transcription, initiation
EXD81_11775	COG1012	belongs to the aldehyde dehydrogenase family
EXD81_11795	COG1956	GAF domain-containing protein
EXD81_11800	COG1309	transcriptional regulator
EXD81_11815	COG1114	Component of the transport system for branched-chain amino acids
EXD81_11820	COG1104	cysteine desulfurase activity
EXD81_11835	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXD81_11840	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXD81_11845	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EXD81_11850	COG0616	signal peptide processing
EXD81_11855	COG1714	RDD family
EXD81_11870	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXD81_11875	COG0827	DNA restriction-modification system
EXD81_11885	COG0521	Mo-molybdopterin cofactor biosynthetic process
EXD81_11945	COG0281	malic enzyme
EXD81_11970	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXD81_11975	COG0628	permease
EXD81_11990	COG0372	Belongs to the citrate synthase family
EXD81_11995	COG0538	isocitrate dehydrogenase activity
EXD81_12005	COG0745	RESPONSE REGULATOR receiver
EXD81_12015	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXD81_12015	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXD81_12020	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EXD81_12025	COG1971	Probably functions as a manganese efflux pump
EXD81_12030	COG0237	dephospho-CoA kinase activity
EXD81_12035	COG0656	L-ascorbic acid biosynthetic process
EXD81_12040	COG2814	Major facilitator Superfamily
EXD81_12045	COG1733	regulation of RNA biosynthetic process
EXD81_12050	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXD81_12070	COG1484	DNA-dependent DNA replication
EXD81_12075	COG0398	Pfam SNARE associated Golgi protein
EXD81_12095	COG3275	phosphorelay sensor kinase activity
EXD81_12100	COG3279	Response regulator of the LytR AlgR family
EXD81_12110	COG1346	cytolysis
EXD81_12115	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EXD81_12125	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXD81_12130	COG3326	Membrane
EXD81_12140	COG1363	Peptidase, m42
EXD81_12145	COG3507	Belongs to the glycosyl hydrolase 43 family
EXD81_12150	COG2160	L-arabinose isomerase activity
EXD81_12160	COG0235	Class ii aldolase
EXD81_12175	COG1653	transport
EXD81_12180	COG1175	transmembrane transport
EXD81_12190	COG3534	alpha-L-arabinofuranosidase
EXD81_12195	COG1966	Carbon starvation protein
EXD81_12200	COG0247	lactate metabolic process
EXD81_12205	COG0277	FAD linked oxidase domain protein
EXD81_12210	COG3835	regulator
EXD81_12245	COG1286	toxin biosynthetic process
EXD81_12250	COG1796	DNA polymerase
EXD81_12250	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXD81_12260	COG3766	membrane
EXD81_12270	COG0318	PFAM AMP-dependent synthetase and ligase
EXD81_12280	COG1024	Enoyl-CoA hydratase
EXD81_12285	COG2086	electron transfer activity
EXD81_12290	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXD81_12295	COG3534	alpha-L-arabinofuranosidase
EXD81_12300	COG3118	belongs to the thioredoxin family
EXD81_12315	COG0527	aspartate kinase activity
EXD81_12325	COG2009	succinate dehydrogenase
EXD81_12335	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXD81_12340	COG0824	Thioesterase
EXD81_12350	COG2856	Zn peptidase
EXD81_12360	COG3620	sequence-specific DNA binding
EXD81_12365	COG1476	TRANSCRIPTIONal
EXD81_12370	COG3617	BRO family, N-terminal domain
EXD81_12400	COG5377	YqaJ viral recombinase family
EXD81_12405	COG3723	Recombinational DNA repair protein, rece pathway
EXD81_12415	COG1484	DNA-dependent DNA replication
EXD81_12520	COG3677	Transposase
EXD81_12715	COG0457	Tetratricopeptide repeat
EXD81_12730	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXD81_12735	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXD81_12740	COG2197	response regulator
EXD81_12755	COG5401	PFAM Sporulation and spore germination
EXD81_12765	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EXD81_12770	COG0622	Phosphoesterase
EXD81_12800	COG0440	acetolactate synthase activity
EXD81_12815	COG0473	3-isopropylmalate dehydrogenase activity
EXD81_12830	COG1477	protein flavinylation
EXD81_12830	COG0457	Tetratricopeptide repeat
EXD81_12850	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EXD81_12870	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXD81_12880	COG1587	Uroporphyrinogen-III synthase
EXD81_12885	COG0113	porphobilinogen synthase activity
EXD81_12895	COG1388	LysM domain
EXD81_12910	COG0525	valine-tRNA ligase activity
EXD81_12915	COG0285	dihydrofolate synthase activity
EXD81_12950	COG1396	sequence-specific DNA binding
EXD81_12970	COG3645	SOS response
EXD81_12970	COG3646	Phage regulatory protein
EXD81_12995	COG0305	Participates in initiation and elongation during chromosome replication
EXD81_13020	COG1595	DNA-templated transcription, initiation
EXD81_13170	COG4824	toxin secretion phage lysis holin
EXD81_13175	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXD81_13175	COG3409	Peptidoglycan-binding domain 1 protein
EXD81_13175	COG1388	LysM domain
EXD81_13200	COG1077	Cell shape determining protein MreB Mrl
EXD81_13205	COG1792	Involved in formation and maintenance of cell shape
EXD81_13210	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EXD81_13220	COG2894	cell division
EXD81_13225	COG0739	heme binding
EXD81_13240	COG2868	ribosomal protein
EXD81_13245	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EXD81_13250	COG3290	protein histidine kinase activity
EXD81_13265	COG0077	Prephenate dehydratase
EXD81_13270	COG1827	regulation of RNA biosynthetic process
EXD81_13275	COG1104	cysteine desulfurase activity
EXD81_13280	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXD81_13295	COG1388	LysM domain
EXD81_13340	COG1862	Preprotein translocase
EXD81_13365	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXD81_13365	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXD81_13370	COG0490	domain, Protein
EXD81_13375	COG5416	Lipopolysaccharide assembly protein A domain
EXD81_13390	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXD81_13400	COG4991	sh3 domain protein
EXD81_13400	COG3103	Sh3 type 3 domain protein
EXD81_13400	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXD81_13420	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXD81_13435	COG1104	cysteine desulfurase activity
EXD81_13445	COG0457	Tetratricopeptide repeat
EXD81_13450	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXD81_13455	COG3881	PFAM PRC-barrel domain
EXD81_13470	COG0765	amino acid transport
EXD81_13475	COG0765	amino acid transport
EXD81_13485	COG1126	abc transporter atp-binding protein
EXD81_13545	COG0768	penicillin binding
EXD81_13570	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXD81_13575	COG0626	cystathionine gamma-synthase activity
EXD81_13585	COG2427	Protein of unknown function (DUF1641)
EXD81_13590	COG3383	formate dehydrogenase (NAD+) activity
EXD81_13595	COG5609	conserved protein (DUF2294)
EXD81_13615	COG2226	methyltransferase
EXD81_13620	COG1309	transcriptional regulator
EXD81_13625	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EXD81_13625	COG2124	cytochrome p450
EXD81_13635	COG0583	DNA-binding transcription factor activity
EXD81_13640	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXD81_13650	COG3711	transcriptional antiterminator
EXD81_13650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXD81_13655	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXD81_13655	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXD81_13655	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXD81_13660	COG1482	cell wall glycoprotein biosynthetic process
EXD81_13685	COG2318	DinB family
EXD81_13705	COG0563	adenylate kinase activity
EXD81_13755	COG0398	Pfam SNARE associated Golgi protein
EXD81_13760	COG0726	polysaccharide deacetylase
EXD81_13765	COG2755	lipolytic protein G-D-S-L family
EXD81_13775	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXD81_13780	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXD81_13785	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXD81_13790	COG1534	Rna-binding protein
EXD81_13800	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXD81_13805	COG0799	negative regulation of ribosome biogenesis
EXD81_13810	COG2226	methyltransferase
EXD81_13815	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXD81_13820	COG1596	polysaccharide export
EXD81_13820	COG1555	photosystem II stabilization
EXD81_13825	COG2131	deaminase
EXD81_13870	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXD81_13900	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXD81_13905	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXD81_13910	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXD81_13915	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXD81_13920	COG1610	YqeY-like protein
EXD81_13925	COG1030	water channel activity
EXD81_13930	COG4864	UPF0365 protein
EXD81_13950	COG1702	phosphate starvation-inducible protein PhoH
EXD81_13955	COG1480	7TM receptor with intracellular HD hydrolase
EXD81_13965	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXD81_13970	COG0295	cytidine deaminase activity
EXD81_13995	COG0751	glycine-tRNA ligase activity
EXD81_14000	COG0517	IMP dehydrogenase activity
EXD81_14015	COG0358	DNA primase activity
EXD81_14020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXD81_14025	COG2010	Cytochrome c
EXD81_14030	COG2384	SAM-dependent methyltransferase
EXD81_14035	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXD81_14065	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXD81_14070	COG0735	belongs to the Fur family
EXD81_14075	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
EXD81_14080	COG4709	membrane
EXD81_14090	COG1388	LysM domain
EXD81_14095	COG5521	maltodextrose utilization protein MalA
EXD81_14100	COG2839	Protein conserved in bacteria
EXD81_14105	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXD81_14110	COG0477	Major facilitator Superfamily
EXD81_14125	COG0573	inorganic phosphate transmembrane transporter activity
EXD81_14130	COG0581	inorganic phosphate transmembrane transporter activity
EXD81_14135	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EXD81_14145	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXD81_14155	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXD81_14160	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXD81_14170	COG1757	Na H antiporter
EXD81_14175	COG4483	Protein conserved in bacteria
EXD81_14180	COG1940	carbohydrate kinase activity
EXD81_14195	COG0011	TIGRFAM Protein of
EXD81_14205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXD81_14215	COG1393	Belongs to the ArsC family
EXD81_14225	COG1366	Belongs to the anti-sigma-factor antagonist family
EXD81_14235	COG0598	Magnesium transport protein CorA
EXD81_14250	COG4537	Required for transformation and DNA binding
EXD81_14255	COG4970	Tfp pilus assembly protein FimT
EXD81_14265	COG4940	Competence protein ComGF
EXD81_14290	COG0681	Belongs to the peptidase S26 family
EXD81_14300	COG1396	sequence-specific DNA binding
EXD81_14335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXD81_14360	COG3872	metal-dependent enzyme
EXD81_14370	COG0006	proline dipeptidase activity
EXD81_14385	COG3854	ATPases associated with a variety of cellular activities
EXD81_14435	COG1302	Protein conserved in bacteria
EXD81_14450	COG1570	exodeoxyribonuclease VII activity
EXD81_14460	COG0142	geranyltranstransferase activity
EXD81_14470	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXD81_14490	COG0745	RESPONSE REGULATOR receiver
EXD81_14500	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXD81_14515	COG1902	pentaerythritol trinitrate reductase activity
EXD81_14535	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXD81_14545	COG0183	Belongs to the thiolase family
EXD81_14550	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXD81_14560	COG0372	Belongs to the citrate synthase family
EXD81_14565	COG2079	MmgE PrpD family protein
EXD81_14570	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXD81_14580	COG3829	transcription factor binding
EXD81_14580	COG3290	protein histidine kinase activity
EXD81_14585	COG0280	phosphate acetyltransferase
EXD81_14590	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXD81_14600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXD81_14605	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXD81_14610	COG0022	dehydrogenase e1 component
EXD81_14615	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXD81_14620	COG1597	lipid kinase activity
EXD81_14630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXD81_14635	COG0765	amino acid transport
EXD81_14640	COG1126	abc transporter atp-binding protein
EXD81_14645	COG4129	membrane
EXD81_14650	COG1376	ErfK ybiS ycfS ynhG family protein
EXD81_14665	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXD81_14685	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EXD81_14690	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EXD81_14705	COG0596	Alpha beta hydrolase
EXD81_14730	COG0250	Participates in transcription elongation, termination and antitermination
EXD81_14760	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_14770	COG0318	PFAM AMP-dependent synthetase and ligase
EXD81_14770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXD81_14770	COG0300	oxidoreductase activity
EXD81_14770	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_14770	COG3321	synthase
EXD81_14800	COG2124	cytochrome p450
EXD81_14810	COG1024	Enoyl-CoA hydratase
EXD81_14815	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXD81_14830	COG3048	D-serine ammonia-lyase activity
EXD81_14840	COG0346	lactoylglutathione lyase activity
EXD81_14865	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXD81_14870	COG0456	acetyltransferase
EXD81_14875	COG2329	Antibiotic biosynthesis monooxygenase
EXD81_14880	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXD81_14880	COG0456	acetyltransferase
EXD81_14885	COG4918	Iron-sulphur cluster biosynthesis
EXD81_14895	COG1073	alpha beta
EXD81_14905	COG0667	Aldo Keto reductase
EXD81_14920	COG1379	DNA repair
EXD81_14925	COG1396	sequence-specific DNA binding
EXD81_14930	COG0252	asparaginase activity
EXD81_14935	COG1027	Aspartate ammonia-lyase
EXD81_14960	COG1300	Membrane
EXD81_14965	COG0735	belongs to the Fur family
EXD81_14980	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXD81_14985	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EXD81_14995	COG1366	Belongs to the anti-sigma-factor antagonist family
EXD81_15040	COG0697	spore germination
EXD81_15050	COG4086	secreted protein
EXD81_15055	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXD81_15065	COG0681	Belongs to the peptidase S26 family
EXD81_15075	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXD81_15075	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXD81_15080	COG0307	riboflavin synthase, alpha
EXD81_15095	COG0456	acetyltransferase
EXD81_15130	COG2715	membrane protein required for spore maturation
EXD81_15135	COG0700	Nucleoside recognition
EXD81_15140	COG1187	pseudouridine synthase activity
EXD81_15145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXD81_15150	COG1333	cytochrome c biogenesis protein
EXD81_15155	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXD81_15160	COG0745	RESPONSE REGULATOR receiver
EXD81_15170	COG1595	DNA-templated transcription, initiation
EXD81_15190	COG1141	Ferredoxin
EXD81_15205	COG1266	CAAX protease self-immunity
EXD81_15220	COG1408	metallophosphoesterase
EXD81_15225	COG4862	establishment of competence for transformation
EXD81_15230	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXD81_15235	COG0492	ferredoxin-NADP+ reductase activity
EXD81_15245	COG3409	Peptidoglycan-binding domain 1 protein
EXD81_15245	COG3773	Cell wall hydrolase
EXD81_15255	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EXD81_15305	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXD81_15310	COG0776	regulation of translation
EXD81_15325	COG0142	geranyltranstransferase activity
EXD81_15335	COG0142	geranyltranstransferase activity
EXD81_15340	COG0105	UTP biosynthetic process
EXD81_15345	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXD81_15360	COG4401	Chorismate mutase type I
EXD81_15365	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXD81_15410	COG0457	Tetratricopeptide repeat
EXD81_15430	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXD81_15440	COG4347	Protein of unknown function (DUF1405)
EXD81_15450	COG2140	Oxalate decarboxylase
EXD81_15455	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXD81_15460	COG1694	Mazg nucleotide pyrophosphohydrolase
EXD81_15475	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXD81_15480	COG0438	transferase activity, transferring glycosyl groups
EXD81_15525	COG0436	Aminotransferase
EXD81_15535	COG3935	DnaD domain protein
EXD81_15540	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXD81_15550	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXD81_15550	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXD81_15590	COG0071	Belongs to the small heat shock protein (HSP20) family
EXD81_15595	COG2190	(PTS) system
EXD81_15600	COG1111	helicase
EXD81_15600	COG1205	dead DEAH box helicase
EXD81_15635	COG0116	Belongs to the methyltransferase superfamily
EXD81_15650	COG1199	ATP-dependent helicase activity
EXD81_15665	COG2233	PERMEase
EXD81_15675	COG1335	isochorismatase
EXD81_15725	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXD81_15735	COG0328	RNA-DNA hybrid ribonuclease activity
EXD81_15740	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EXD81_15745	COG0328	RNA-DNA hybrid ribonuclease activity
EXD81_15765	COG1278	Cold shock
EXD81_15775	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXD81_15785	COG0386	Belongs to the glutathione peroxidase family
EXD81_15790	COG1418	mRNA catabolic process
EXD81_15795	COG1413	lyase activity
EXD81_15810	COG2136	Putative SAM-dependent methyltransferase
EXD81_15810	COG2521	methyltransferase
EXD81_15825	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXD81_15830	COG0204	Acyl-transferase
EXD81_15835	COG1272	protein, Hemolysin III
EXD81_15840	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXD81_15845	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXD81_15860	COG2755	lipolytic protein G-D-S-L family
EXD81_15865	COG4698	Protein conserved in bacteria
EXD81_15885	COG1086	Polysaccharide biosynthesis protein
EXD81_15895	COG4641	Protein conserved in bacteria
EXD81_15910	COG0463	Glycosyl transferase, family 2
EXD81_15915	COG0456	acetyltransferase
EXD81_15925	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EXD81_15930	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXD81_15935	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXD81_15940	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXD81_15945	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXD81_15950	COG0456	acetyltransferase
EXD81_15955	COG1509	lysine 2,3-aminomutase activity
EXD81_15985	COG0671	phosphoesterase, PA-phosphatase related
EXD81_16015	COG2226	methyltransferase
EXD81_16020	COG3409	Peptidoglycan-binding domain 1 protein
EXD81_16020	COG0793	Belongs to the peptidase S41A family
EXD81_16055	COG0346	lactoylglutathione lyase activity
EXD81_16060	COG0400	carboxylic ester hydrolase activity
EXD81_16065	COG0778	Nitroreductase
EXD81_16070	COG1733	regulation of RNA biosynthetic process
EXD81_16080	COG1942	4-Oxalocrotonate Tautomerase
EXD81_16105	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXD81_16110	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXD81_16115	COG1366	Belongs to the anti-sigma-factor antagonist family
EXD81_16120	COG0534	Mate efflux family protein
EXD81_16125	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXD81_16130	COG1819	glycosyl
EXD81_16140	COG2032	superoxide dismutase activity
EXD81_16145	COG0714	Associated with various cellular activities
EXD81_16160	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXD81_16165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXD81_16170	COG0385	Bile acid
EXD81_16185	COG1657	PFAM Prenyltransferase squalene oxidase
EXD81_16235	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXD81_16240	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EXD81_16250	COG0514	ATP-dependent DNA helicase (RecQ)
EXD81_16255	COG3584	3D domain protein
EXD81_16255	COG1388	LysM domain
EXD81_16265	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXD81_16285	COG0741	lytic transglycosylase activity
EXD81_16290	COG0640	Transcriptional regulator
EXD81_16300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXD81_16305	COG1309	transcriptional regulator
EXD81_16310	COG2207	Transcriptional regulator
EXD81_16310	COG0662	Cupin 2, conserved barrel domain protein
EXD81_16315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXD81_16355	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXD81_16360	COG1070	Carbohydrate kinase
EXD81_16375	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EXD81_16380	COG0300	oxidoreductase activity
EXD81_16405	COG0583	DNA-binding transcription factor activity
EXD81_16415	COG0493	'glutamate synthase
EXD81_16425	COG0604	alcohol dehydrogenase
EXD81_16435	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXD81_16440	COG0640	Transcriptional regulator
EXD81_16445	COG2814	Major facilitator Superfamily
EXD81_16450	COG0405	Gamma-glutamyltransferase
EXD81_16455	COG0166	Belongs to the GPI family
EXD81_16460	COG0582	viral genome integration into host DNA
EXD81_16475	COG0534	Mate efflux family protein
EXD81_16480	COG2017	converts alpha-aldose to the beta-anomer
EXD81_16485	COG2027	D-alanyl-D-alanine carboxypeptidase
EXD81_16500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXD81_16505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXD81_16515	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EXD81_16515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXD81_16525	COG1649	PFAM Uncharacterised BCR, COG1649
EXD81_16530	COG1960	acyl-CoA dehydrogenase activity
EXD81_16535	COG0318	PFAM AMP-dependent synthetase and ligase
EXD81_16540	COG0439	Biotin carboxylase
EXD81_16545	COG0511	ligase activity, forming carbon-carbon bonds
EXD81_16550	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXD81_16555	COG1024	Enoyl-CoA hydratase
EXD81_16560	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXD81_16565	COG0586	Pfam SNARE associated Golgi protein
EXD81_16570	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXD81_16575	COG2246	polysaccharide biosynthetic process
EXD81_16585	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXD81_16600	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXD81_16610	COG2610	gluconate transmembrane transporter activity
EXD81_16615	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXD81_16620	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXD81_16625	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_16650	COG3507	Belongs to the glycosyl hydrolase 43 family
EXD81_16665	COG2205	protein histidine kinase activity
EXD81_16695	COG0577	efflux transmembrane transporter activity
EXD81_16695	COG1136	(ABC) transporter
EXD81_16725	COG2271	Major facilitator Superfamily
EXD81_16730	COG1609	Transcriptional regulator
EXD81_16735	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_16740	COG1312	Catalyzes the dehydration of D-mannonate
EXD81_16745	COG0800	Aldolase
EXD81_16750	COG1063	alcohol dehydrogenase
EXD81_16760	COG1115	amino acid carrier protein
EXD81_16770	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXD81_16780	COG1832	CoA-binding protein
EXD81_16790	COG4841	protein insertion into membrane
EXD81_16800	COG0824	Thioesterase
EXD81_16820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXD81_16825	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXD81_16840	COG0071	Belongs to the small heat shock protein (HSP20) family
EXD81_16850	COG4846	Membrane protein involved in cytochrome C biogenesis
EXD81_16855	COG2201	protein-glutamate methylesterase activity
EXD81_16860	COG0785	Cytochrome C biogenesis protein
EXD81_16890	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXD81_16920	COG4195	phage-related replication protein
EXD81_16930	COG0756	dUTP diphosphatase activity
EXD81_16935	COG5434	Belongs to the glycosyl hydrolase 28 family
EXD81_16960	COG3397	chitin binding
EXD81_16995	COG0456	acetyltransferase
EXD81_17015	COG1064	alcohol dehydrogenase
EXD81_17050	COG3848	Pyruvate phosphate dikinase
EXD81_17050	COG0574	Belongs to the PEP-utilizing enzyme family
EXD81_17055	COG1070	Carbohydrate kinase
EXD81_17075	COG2211	Major facilitator Superfamily
EXD81_17085	COG0174	glutamine synthetase
EXD81_17095	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXD81_17100	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXD81_17105	COG0464	growth
EXD81_17115	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXD81_17120	COG4112	unkown
EXD81_17170	COG2076	Multidrug Resistance protein
EXD81_17180	COG1764	response to oxidative stress
EXD81_17185	COG4195	phage-related replication protein
EXD81_17195	COG1404	Belongs to the peptidase S8 family
EXD81_17215	COG2124	cytochrome p450
EXD81_17220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXD81_17220	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXD81_17220	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EXD81_17220	COG3321	synthase
EXD81_17250	COG1024	Enoyl-CoA hydratase
EXD81_17255	COG3425	synthase
EXD81_17260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXD81_17330	COG2359	stage V sporulation protein S
EXD81_17335	COG1692	metallophosphoesterase
EXD81_17345	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXD81_17360	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXD81_17365	COG1426	Protein conserved in bacteria
EXD81_17380	COG0300	oxidoreductase activity
EXD81_17390	COG0612	Peptidase, M16
EXD81_17400	COG1846	Transcriptional regulator
EXD81_17405	COG2814	Major facilitator Superfamily
EXD81_17410	COG2188	Transcriptional regulator
EXD81_17425	COG0740	serine-type endopeptidase activity
EXD81_17430	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXD81_17440	COG0527	aspartate kinase activity
EXD81_17445	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXD81_17455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXD81_17460	COG1873	PFAM PRC-barrel domain
EXD81_17465	COG0612	Peptidase, M16
EXD81_17470	COG0726	polysaccharide deacetylase
EXD81_17485	COG0196	riboflavin kinase activity
EXD81_17500	COG1550	Protein conserved in bacteria
EXD81_17510	COG1358	cellular component organization or biogenesis
EXD81_17515	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXD81_17520	COG0195	Participates in both transcription termination and antitermination
EXD81_17540	COG0750	zinc metalloprotease
EXD81_17555	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EXD81_17585	COG1191	sigma factor activity
EXD81_17595	COG1776	CheC inhibitor of MCP methylation
EXD81_17600	COG0835	chemotaxis
EXD81_17605	COG0643	Histidine kinase
EXD81_17605	COG2198	Histidine kinase
EXD81_17610	COG2201	protein-glutamate methylesterase activity
EXD81_17615	COG0455	bacterial-type flagellum organization
EXD81_17620	COG1419	protein localization to endoplasmic reticulum
EXD81_17640	COG1987	bacterial-type flagellum assembly
EXD81_17645	COG1338	Plays a role in the flagellum-specific transport system
EXD81_17655	COG2201	protein-glutamate methylesterase activity
EXD81_17660	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXD81_17660	COG1776	CheC inhibitor of MCP methylation
EXD81_17670	COG1580	Controls the rotational direction of flagella during chemotaxis
EXD81_17675	COG1582	Flagellar protein (FlbD)
EXD81_17680	COG4786	Flagellar basal body rod
EXD81_17685	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EXD81_17690	COG3144	bacterial-type flagellum assembly
EXD81_17700	COG2882	bacterial-type flagellum organization
EXD81_17705	COG1157	protein secretion by the type III secretion system
EXD81_17710	COG1317	bacterial-type flagellum organization
EXD81_17715	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXD81_17720	COG1766	The M ring may be actively involved in energy transduction
EXD81_17725	COG1677	Flagellar hook-basal body complex protein FliE
EXD81_17730	COG1558	bacterial-type flagellum-dependent cell motility
EXD81_17735	COG1815	bacterial-type flagellum-dependent cell motility
EXD81_17765	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXD81_17775	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXD81_17785	COG2257	FlhB HrpN YscU SpaS Family
EXD81_17800	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXD81_17825	COG1837	Belongs to the UPF0109 family
EXD81_17865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXD81_17870	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_17875	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXD81_17895	COG1760	l-serine dehydratase
EXD81_17900	COG1760	l-serine dehydratase
EXD81_17905	COG1461	Dihydroxyacetone kinase
EXD81_17910	COG1302	Protein conserved in bacteria
EXD81_17925	COG1564	THIamine pyrophosphokinase
EXD81_17930	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXD81_17940	COG2815	serine threonine protein kinase
EXD81_17940	COG0515	serine threonine protein kinase
EXD81_17945	COG0631	protein serine/threonine phosphatase activity
EXD81_17955	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXD81_17955	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXD81_17965	COG0242	peptide deformylase activity
EXD81_17975	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXD81_17985	COG0194	GDP metabolic process
EXD81_17990	COG2052	Domain of unknown function (DUF370)
EXD81_17995	COG1561	YicC-like family, N-terminal region
EXD81_18015	COG1648	precorrin-2 dehydrogenase activity
EXD81_18020	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
EXD81_18025	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXD81_18040	COG0306	phosphate transporter
EXD81_18055	COG0284	orotidine-5'-phosphate decarboxylase activity
EXD81_18075	COG0505	Belongs to the CarA family
EXD81_18090	COG2233	PERMEase
EXD81_18100	COG0564	pseudouridine synthase activity
EXD81_18110	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXD81_18115	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EXD81_18125	COG3599	regulation of cell shape
EXD81_18130	COG2302	S4 RNA-binding domain
EXD81_18135	COG0762	integral membrane protein
EXD81_18145	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXD81_18155	COG1873	PFAM PRC-barrel domain
EXD81_18160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXD81_18170	COG1191	sigma factor activity
EXD81_18175	COG1191	sigma factor activity
EXD81_18190	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXD81_18200	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXD81_18215	COG0772	Belongs to the SEDS family
EXD81_18245	COG4839	cell division protein FtsL
EXD81_18265	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXD81_18280	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXD81_18285	COG1399	metal-binding, possibly nucleic acid-binding protein
EXD81_18300	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXD81_18305	COG3314	Sporulation integral membrane protein YlbJ
EXD81_18315	COG0742	ribosomal rna small subunit methyltransferase
EXD81_18325	COG3679	Belongs to the UPF0342 family
EXD81_18340	COG2340	Cysteine-rich secretory protein family
EXD81_18345	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXD81_18355	COG3336	cytochrome c oxidase
EXD81_18360	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EXD81_18365	COG1845	cytochrome c oxidase, subunit III
EXD81_18425	COG4896	Protein conserved in bacteria
EXD81_18460	COG3227	Zinc metalloprotease (Elastase)
EXD81_18470	COG0483	inositol monophosphate 1-phosphatase activity
EXD81_18495	COG1982	Orn Lys Arg decarboxylase major
EXD81_18510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXD81_18515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXD81_18520	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXD81_18525	COG0022	dehydrogenase e1 component
EXD81_18530	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXD81_18535	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXD81_18545	COG3321	synthase
EXD81_18545	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_18545	COG0300	oxidoreductase activity
EXD81_18545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXD81_18545	COG0318	PFAM AMP-dependent synthetase and ligase
EXD81_18595	COG0242	peptide deformylase activity
EXD81_18600	COG0561	phosphatase activity
EXD81_18610	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXD81_18620	COG0569	domain protein
EXD81_18625	COG2105	PFAM AIG2 family protein
EXD81_18625	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EXD81_18630	COG3852	Histidine kinase
EXD81_18635	COG2002	toxin-antitoxin pair type II binding
EXD81_18645	COG1077	Cell shape determining protein MreB Mrl
EXD81_18655	COG2309	aminopeptidase activity
EXD81_18660	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXD81_18665	COG0488	(ABC) transporter
EXD81_18680	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXD81_18680	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXD81_18680	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXD81_18690	COG1349	DNA-binding transcription factor activity
EXD81_18700	COG1136	(ABC) transporter
EXD81_18715	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EXD81_18720	COG0314	molybdopterin synthase activity
EXD81_18725	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXD81_18735	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXD81_18755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXD81_18760	COG0668	transmembrane transport
EXD81_18780	COG0716	FMN binding
EXD81_18795	COG0583	DNA-binding transcription factor activity
EXD81_18800	COG0517	IMP dehydrogenase activity
EXD81_18810	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXD81_18815	COG4703	Protein of unknown function (DUF1797)
EXD81_18835	COG1408	metallophosphoesterase
EXD81_18840	COG1376	ErfK ybiS ycfS ynhG family protein
EXD81_18845	COG2814	Major facilitator Superfamily
EXD81_18855	COG0835	chemotaxis
EXD81_18855	COG0784	Response regulator, receiver
EXD81_18875	COG0768	penicillin binding
EXD81_18880	COG2340	Cysteine-rich secretory protein family
EXD81_18900	COG2084	Dehydrogenase
EXD81_18905	COG0840	transmembrane signaling receptor activity
EXD81_18910	COG1533	DNA photolyase activity
EXD81_18920	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EXD81_18925	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXD81_18930	COG2190	(PTS) system
EXD81_18930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXD81_18930	COG1263	PTS System
EXD81_18935	COG3711	transcriptional antiterminator
EXD81_18940	COG1609	Transcriptional regulator
EXD81_18945	COG0006	proline dipeptidase activity
EXD81_18950	COG2217	Heavy metal translocating P-type atpase
EXD81_18955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXD81_18960	COG2244	polysaccharide biosynthetic process
EXD81_18965	COG3773	Cell wall hydrolase
EXD81_18975	COG4873	Protein conserved in bacteria
EXD81_18990	COG1028	Short-chain dehydrogenase reductase Sdr
EXD81_18995	COG1733	regulation of RNA biosynthetic process
EXD81_19005	COG0602	queuosine metabolic process
EXD81_19010	COG0720	synthase
EXD81_19025	COG3949	Membrane
EXD81_19035	COG0542	response to heat
EXD81_19040	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXD81_19050	COG1846	Transcriptional regulator
EXD81_19055	COG3852	Histidine kinase
EXD81_19085	COG0436	Aminotransferase
EXD81_19090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXD81_19105	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXD81_19110	COG5002	protein histidine kinase activity
EXD81_19115	COG3594	Acyltransferase
EXD81_19125	COG2323	membrane
EXD81_19130	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXD81_19155	COG1191	sigma factor activity
EXD81_19160	COG0861	Integral membrane protein TerC family
EXD81_19165	COG0586	Pfam SNARE associated Golgi protein
EXD81_19170	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EXD81_19185	COG1846	Transcriptional regulator
EXD81_19200	COG0789	Transcriptional regulator
EXD81_19205	COG2239	Acts as a magnesium transporter
EXD81_19225	COG1388	LysM domain
EXD81_19225	COG3858	chitin binding
EXD81_19230	COG4721	ABC-type cobalt transport system, permease component
EXD81_19235	COG1122	ATPase activity
EXD81_19240	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXD81_19245	COG1366	Belongs to the anti-sigma-factor antagonist family
EXD81_19250	COG1404	Belongs to the peptidase S8 family
EXD81_19260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXD81_19265	COG2814	Major facilitator Superfamily
EXD81_19275	COG0457	Tetratricopeptide repeat
EXD81_19275	COG0463	Glycosyl transferase, family 2
EXD81_19290	COG1764	response to oxidative stress
EXD81_19295	COG1846	Transcriptional regulator
EXD81_19300	COG1764	response to oxidative stress
EXD81_19310	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXD81_19315	COG0788	formyltetrahydrofolate deformylase activity
EXD81_19320	COG2076	Multidrug Resistance protein
EXD81_19325	COG2076	Multidrug Resistance protein
EXD81_19330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXD81_19335	COG1607	acyl-coa hydrolase
EXD81_19340	COG1834	amidinotransferase
EXD81_19345	COG2706	6-phosphogluconolactonase activity
EXD81_19350	COG4608	Belongs to the ABC transporter superfamily
EXD81_19365	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXD81_19370	COG4166	transmembrane transport
EXD81_19375	COG0444	Belongs to the ABC transporter superfamily
EXD81_19380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXD81_19385	COG0601	transmembrane transport
EXD81_19390	COG2362	D-Aminopeptidase
EXD81_19395	COG0477	Major facilitator Superfamily
EXD81_19400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXD81_19405	COG0463	Glycosyl transferase, family 2
EXD81_19415	COG0346	lactoylglutathione lyase activity
EXD81_19420	COG0531	amino acid
EXD81_19425	COG1392	Phosphate transport regulator
EXD81_19430	COG0306	phosphate transporter
EXD81_19445	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXD81_19445	COG3409	Peptidoglycan-binding domain 1 protein
EXD81_19485	COG3778	Protein conserved in bacteria
EXD81_19490	COG3299	homolog of phage Mu protein gp47
EXD81_19495	COG3628	GPW Gp25 family protein
EXD81_19505	COG4193	domain, Protein
EXD81_19510	COG1652	LysM domain
EXD81_19565	COG4653	Phage capsid family
EXD81_19570	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EXD81_19575	COG5518	Phage portal protein
EXD81_19580	COG1783	phage Terminase large subunit
EXD81_19585	COG3728	DNA packaging
EXD81_19585	COG5484	DNA packaging
EXD81_19590	COG1595	DNA-templated transcription, initiation
EXD81_19605	COG1484	DNA-dependent DNA replication
EXD81_19610	COG1522	sequence-specific DNA binding
EXD81_19620	COG1396	sequence-specific DNA binding
EXD81_19625	COG2856	Zn peptidase
EXD81_19635	COG4195	phage-related replication protein
EXD81_19650	COG0457	Tetratricopeptide repeat
EXD81_19655	COG2318	DinB family
EXD81_19660	COG0730	response to heat
EXD81_19685	COG2197	response regulator
EXD81_19690	COG4585	Histidine kinase
EXD81_19710	COG2205	protein histidine kinase activity
EXD81_19710	COG2770	Histidine kinase
EXD81_19715	COG0745	RESPONSE REGULATOR receiver
EXD81_19720	COG2721	sulfolactate sulfo-lyase activity
EXD81_19725	COG0246	Mannitol dehydrogenase
EXD81_19730	COG1609	Transcriptional regulator
EXD81_19735	COG2211	Major facilitator Superfamily
EXD81_19745	COG1252	NADH dehydrogenase
EXD81_19755	COG4297	protein containing double-stranded beta helix domain
EXD81_19760	COG0697	spore germination
EXD81_19765	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EXD81_19770	COG0390	transport system, permease component
EXD81_19775	COG1587	Uroporphyrinogen-III synthase
EXD81_19785	COG1819	glycosyl
EXD81_19795	COG2427	Protein of unknown function (DUF1641)
EXD81_19810	COG2205	protein histidine kinase activity
EXD81_19825	COG1285	pathogenesis
EXD81_19855	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXD81_19870	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXD81_19885	COG1846	Transcriptional regulator
EXD81_19895	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EXD81_19900	COG2367	Beta-lactamase
EXD81_19930	COG0626	cystathionine gamma-synthase activity
EXD81_19935	COG0626	cystathionine gamma-synthase activity
EXD81_19940	COG2382	esterase
EXD81_19950	COG2153	protein acetylation
EXD81_19980	COG0210	DNA helicase
EXD81_20035	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EXD81_20040	COG0351	phosphomethylpyrimidine kinase
EXD81_20045	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXD81_20065	COG0352	thiamine-phosphate diphosphorylase activity
EXD81_20075	COG0569	domain protein
EXD81_20075	COG0475	glutathione-regulated potassium exporter activity
EXD81_20090	COG0564	pseudouridine synthase activity
EXD81_20100	COG2357	RelA SpoT domain protein
EXD81_20115	COG0741	lytic transglycosylase activity
EXD81_20120	COG2346	COG2346, Truncated hemoglobins
EXD81_20130	COG1164	Oligoendopeptidase f
EXD81_20140	COG4862	establishment of competence for transformation
EXD81_20145	COG0861	Integral membrane protein TerC family
EXD81_20150	COG1393	Belongs to the ArsC family
EXD81_20155	COG0456	acetyltransferase
EXD81_20165	COG4608	Belongs to the ABC transporter superfamily
EXD81_20170	COG0444	Belongs to the ABC transporter superfamily
EXD81_20175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXD81_20180	COG0601	transmembrane transport
EXD81_20190	COG0180	Tryptophanyl-tRNA synthetase
EXD81_20200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXD81_20205	COG0601	transmembrane transport
EXD81_20220	COG0444	Belongs to the ABC transporter superfamily
EXD81_20225	COG5504	Zn-dependent protease
EXD81_20235	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXD81_20250	COG1744	ABC transporter substrate-binding protein PnrA-like
EXD81_20260	COG2267	carboxylic ester hydrolase activity
EXD81_20280	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EXD81_20285	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXD81_20290	COG0505	Belongs to the CarA family
EXD81_20295	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXD81_20315	COG2271	Major facilitator Superfamily
EXD81_20330	COG2151	metal-sulfur cluster biosynthetic enzyme
EXD81_20335	COG1073	alpha beta
EXD81_20340	COG0561	phosphatase activity
EXD81_20355	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXD81_20360	COG1307	EDD domain protein, DegV family
EXD81_20370	COG2124	cytochrome p450
EXD81_20375	COG0840	transmembrane signaling receptor activity
EXD81_20385	COG2996	Protein conserved in bacteria